Azides: Organic or inorganic compounds that contain the -N3 group.Sodium Azide: A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed)Click Chemistry: Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.Alkynes: Hydrocarbons with at least one triple bond in the linear portion, of the general formula Cn-H2n-2.Cyanides: Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.Cyclization: Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Dinitrophenols: Organic compounds that contain two nitro groups attached to a phenol.Ascorbate Oxidase: An enzyme that converts ascorbic acid to dehydroascorbic acid. EC 1.10.3.3.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.PhotochemistryKinetics: The rate dynamics in chemical or physical systems.PeroxidasesHydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Cycloaddition Reaction: Synthetic organic reactions that use reactions between unsaturated molecules to form cyclical products.Copper: A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.Fluorides: Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.Hydrogen Peroxide: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.Catalysis: The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.Catalase: An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA.Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.Explosive Agents: Substances that are energetically unstable and can produce a sudden expansion of the material, called an explosion, which is accompanied by heat, pressure and noise. Other things which have been described as explosive that are not included here are explosive action of laser heating, human performance, sudden epidemiological outbreaks, or fast cell growth.Sanitary Engineering: A branch of engineering concerned with the design, construction, and maintenance of environmental facilities conducive to public health, such as water supply and waste disposal.Newspapers: Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)Mutagenicity Tests: Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Dictionaries, ChemicalTerminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Affinity Labels: Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.Vinyl CompoundsVinyl Chloride: A gas that has been used as an aerosol propellant and is the starting material for polyvinyl resins. Toxicity studies have shown various adverse effects, particularly the occurrence of liver neoplasms.Micropore Filters: A membrane or barrier with micrometer sized pores used for separation purification processes.Filtration: A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Anura: An order of the class Amphibia, which includes several families of frogs and toads. They are characterized by well developed hind limbs adapted for jumping, fused head and trunk and webbed toes. The term "toad" is ambiguous and is properly applied only to the family Bufonidae.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Water Microbiology: The presence of bacteria, viruses, and fungi in water. This term is not restricted to pathogenic organisms.Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.Firefly Luciferin: A benzothaizole which is oxidized by LUCIFERASES, FIREFLY to cause emission of light (LUMINESCENCE).Biotin: A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.Oximes: Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.Aequorin: A photoprotein isolated from the bioluminescent jellyfish Aequorea. It emits visible light by an intramolecular reaction when a trace amount of calcium ion is added. The light-emitting moiety in the bioluminescence reaction is believed to be 2-amino-3-benzyl-5-(p-hydroxyphenyl)pyrazine (AF-350).Allergy and Immunology: A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Antibody Specificity: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.Antibodies, Viral: Immunoglobulins produced in response to VIRAL ANTIGENS.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Autophagy: The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.Phagosomes: Membrane-bound cytoplasmic vesicles formed by invagination of phagocytized material. They fuse with lysosomes to form phagolysosomes in which the hydrolytic enzymes of the lysosome digest the phagocytized material.Microtubule-Associated Proteins: High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules.Yttrium: An element of the rare earth family of metals. It has the atomic symbol Y, atomic number 39, and atomic weight 88.91. In conjunction with other rare earths, yttrium is used as a phosphor in television receivers and is a component of the yttrium-aluminum garnet (YAG) lasers.Commerce: The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)Silicon Compounds: Inorganic compounds that contain silicon as an integral part of the molecule.International Cooperation: The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.Macau: Special Administrative Region of the People's Republic of China since December 20, 1999 with its own constitution. The island of Macau and adjacent islands are located off the southeast coast of China.Intellectual Property: Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)

Cross-linking of two beta subunits in the closed conformation in F1-ATPase. (1/2265)

In the crystal structure of mitochondrial F1-ATPase, two beta subunits with a bound Mg-nucleotide are in "closed" conformations, whereas the third beta subunit without bound nucleotide is in an "open" conformation. In this "CCO" (beta-closed beta-closed beta-open) conformational state, Ile-390s of the two closed beta subunits, even though they are separated by an intervening alpha subunit, have a direct contact. We replaced the equivalent Ile of the alpha3beta3gamma subcomplex of thermophilic F1-ATPase with Cys and observed the formation of the beta-beta cross-link through a disulfide bond. The analysis of conditions required for the cross-link formation indicates that: (i) F1-ATPase takes the CCO conformation when two catalytic sites are filled with Mg-nucleotide, (ii) intermediate(s) with the CCO conformation are generated during catalytic cycle, (iii) the Mg-ADP inhibited form is in the CCO conformation, and (iv) F1-ATPase dwells in conformational state(s) other than CCO when only one (or none) of catalytic sites is filled by Mg-nucleotide or when catalytic sites are filled by Mg2+-free nucleotide. The alpha3beta3gamma subcomplex containing the beta-beta cross-link retained the activity of uni-site catalysis but lost that of multiple catalytic turnover, suggesting that open-closed transition of beta subunits is required for the rotation of gamma subunit but not for hydrolysis of a single ATP.  (+info)

Activation of Go-proteins by membrane depolarization traced by in situ photoaffinity labeling of galphao-proteins with [alpha32P]GTP-azidoanilide. (2/2265)

Evidence for depolarization-induced activation of G-proteins in membranes of rat brain synaptoneurosomes has been previously reported (Cohen-Armon, M., and Sokolovsky, M. (1991) J. Biol. Chem. 266, 2595-2605; Cohen-Armon, M., and Sokolovsky, M. (1993) J. Biol. Chem. 268, 9824-9838). In the present work we identify the activated G-proteins as Go-proteins by tracing their depolarization-induced in situ photoaffinity labeling with [alpha32P]GTP-azidoanilide (GTPAA). Labeled GTPAA was introduced into transiently permeabilized rat brain-stem synaptoneurosomes. The resealed synaptoneurosomes, while being UV-irradiated, were depolarized. Relative to synaptoneurosomes at resting potential, the covalent binding of [alpha32P]GTPAA to Galphao1- and Galphao3-proteins, but not to Galphao2- isoforms, was enhanced by 5- to 7-fold in depolarized synaptoneurosomes, thereby implying an accelerated exchange of GDP for [alpha32P]GTPAA. Their depolarization-induced photoaffinity labeling was independent of stimulation of Go-protein-coupled receptors and could be reversed by membrane repolarization, thus excluding induction by transmitters release. It was, however, dependent on depolarization-induced activation of the voltage-gated sodium channels (VGSC), regardless of Na+ current. The alpha subunit of VGSC was cross-linked and co-immunoprecipitated with Galphao-proteins in depolarized brain-stem and cortical synaptoneurosomes. VGSC alpha subunit most efficiently cross-linked with guanosine 5'-O-2-thiodiphosphate-bound rather than to guanosine 5'-O-(3-thiotriphosphate)-bound Galphao-proteins in isolated synaptoneurosomal membranes. These findings support a possible involvement of VGSC in depolarization-induced activation of Go-proteins.  (+info)

Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity. (3/2265)

G protein-coupled receptors are commonly thought to bind their cognate ligands and elicit functional responses primarily as monomeric receptors. In studying the recombinant gamma-aminobutyric acid, type B (GABAB) receptor (gb1a) and a GABAB-like orphan receptor (gb2), we observed that both receptors are functionally inactive when expressed individually in multiple heterologous systems. Characterization of the tissue distribution of each of the receptors by in situ hybridization histochemistry in rat brain revealed co-localization of gb1 and gb2 transcripts in many brain regions, suggesting the hypothesis that gb1 and gb2 may interact in vivo. In three established functional systems (inwardly rectifying K+ channel currents in Xenopus oocytes, melanophore pigment aggregation, and direct cAMP measurements in HEK-293 cells), GABA mediated a functional response in cells coexpressing gb1a and gb2 but not in cells expressing either receptor individually. This GABA activity could be blocked with the GABAB receptor antagonist CGP71872. In COS-7 cells coexpressing gb1a and gb2 receptors, co-immunoprecipitation of gb1a and gb2 receptors was demonstrated, indicating that gb1a and gb2 act as subunits in the formation of a functional GABAB receptor.  (+info)

Resolution of the paradox of red cell shape changes in low and high pH. (4/2265)

The molecular basis of cell shape regulation in acidic pH was investigated in human erythrocytes. Intact erythrocytes maintain normal shape in the cell pH range 6.3-7.9, but invaginate at lower pH values. However, consistent with predicted pH-dependent changes in the erythrocyte membrane skeleton, isolated erythrocyte membranes evaginate in acidic pH. Moreover, intact cells evaginate at pH greater than 7.9, but isolated membranes invaginate in this condition. Labeling with the hydrophobic, photoactivatable probe 5-[125I]iodonaphthyl-1-azide demonstrated pH-dependent hydrophobic insertion of an amphitropic protein into membranes of intact cells but not into isolated membranes. Based on molecular weight and on reconstitution experiments using stripped inside-out vesicles, the most likely candidate for the variably labeled protein is glyceraldehyde-3-phosphate dehydrogenase. Resealing of isolated membranes reconstituted both the shape changes and the hydrophobic labeling profile seen in intact cells. This observation appears to resolve the paradox of the contradictory pH dependence of shape changes of intact cells and isolated membranes. In intact erythrocytes, the demonstrated protein-membrane interaction would oppose pH-dependent shape effects of the spectrin membrane skeleton, stabilizing cell shape in moderately abnormal pH. Stabilization of erythrocyte shape in moderately acidic pH may prevent inappropriate red cell destruction in the spleen.  (+info)

Analysis of the membrane-interacting domains of myelin basic protein by hydrophobic photolabeling. (5/2265)

Myelin basic protein is a water soluble membrane protein which interacts with acidic lipids through some type of hydrophobic interaction in addition to electrostatic interactions. Here we show that it can be labeled from within the lipid bilayer when bound to acidic lipids with the hydrophobic photolabel 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine (TID) and by two lipid photolabels. The latter included one with the reactive group near the apolar/polar interface and one with the reactive group linked to an acyl chain to position it deeper in the bilayer. The regions of the protein which interact hydrophobically with lipid to the greatest extent were determined by cleaving the TID-labeled myelin basic protein (MBP) with cathepsin D into peptides 1-43, 44-89, and 90-170. All three peptides from lipid-bound protein were labeled much more than peptides from the protein labeled in solution. However, the peptide labeling pattern was similar for both environments. The two peptides in the N-terminal half were labeled similarly and about twice as much as the C-terminal peptide indicating that the N-terminal half interacts hydrophobically with lipid more than the C-terminal half. MBP can be modified post-translationally in vivo, including by deamidation, which may alter its interactions with lipid. However, deamidation had no effect on the TID labeling of MBP or on the labeling pattern of the cathepsin D peptides. The site of deamidation has been reported to be in the C-terminal half, and its lack of effect on hydrophobic interactions of MBP with lipid are consistent with the conclusion that the N-terminal half interacts hydrophobically more than the C-terminal half. Since other studies of the interaction of isolated N-terminal and C-terminal peptides with lipid also indicate that the N-terminal half interacts hydrophobically with lipid more than the C-terminal half, these results from photolabeling of the intact protein suggest that the N-terminal half of the intact protein interacts with lipid in a similar way as the isolated peptide. The similar behavior of the intact protein to that of its isolated peptides suggests that when the purified protein binds to acidic lipids, it is in a conformation which allows both halves of the protein to interact independently with the lipid bilayer. That is, it does not form a hydrophobic domain made up from different parts of the protein.  (+info)

Selective inhibition of MDR1 P-glycoprotein-mediated transport by the acridone carboxamide derivative GG918. (6/2265)

The acridone carboxamide derivative GG918 (N-{4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)-ethyl]-pheny l}-9,10dihydro-5-methoxy-9-oxo-4-acridine carboxamide) is a potent inhibitor of MDR1 P-glycoprotein-mediated multidrug resistance. Direct measurements of ATP-dependent MDR1 P-glycoprotein-mediated transport in plasma membrane vesicles from human and rat hepatocyte canalicular membranes indicated 50% inhibition at GG918 concentrations between 8 nM and 80 nM using N-pentyl-[3H]quinidinium, ['4C]doxorubicin and [3H]daunorubicin as substrates. The inhibition constant K for GG918 was 35 nM in rat hepatocyte canalicular membrane vesicles with [3H]daunorubicin as the substrate. Photoaffinity labelling of canalicular and recombinant rat Mdr1b P-glycoprotein by [3H]azidopine was suppressed by 10 muM and 40 muM GG918. The high selectivity of GG918-induced inhibition was demonstrated in canalicular membrane vesicles and by analysis of the hepatobiliary elimination in rats using [3H]daunorubicin, [3H]taurocholate and [3H]cysteinyl leukotrienes as substrates for three distinct ATP-dependent export pumps. Almost complete inhibition of [3H]daunorubicin transport was observed at GG918 concentrations that did not affect the other hepatocyte canalicular export pumps. The high potency and selectivity of GG918 for the inhibition of human MDR1 and rat Mdr1b P-glycoprotein may serve to interfere with this type of multidrug resistance and provides a tool for studies on the function of these ATP-dependent transport proteins.  (+info)

Influence of bioenergetic stress on heat shock protein gene expression in nucleated red blood cells of fish. (7/2265)

The physiological and biochemical signals that induce stress protein (HSP) synthesis remain conjectural. In this study, we used the nucleated red blood cells from rainbow trout, Oncorhynchus mykiss, to address the interaction between energy status and HSP gene expression. Heat shock (25 degrees C) did not significantly affect ATP levels but resulted in an increase in HSP70 mRNA. Hypoxia alone did not induce HSP transcription in these cells despite a significant depression in ATP. Inhibition of oxidative phosphorylation with azide, in the absence of thermal stress, decreased ATP by 56% and increased lactate production by 62% but did not induce HSP gene transcription. Inhibition of oxidative phosphorylation and glycolysis with azide and iodoacetic acid respectively, decreased ATP by 79% and prevented lactate production, but did not induce either HSP70 or HSP30 gene transcription in these cells. This study demonstrates that a reduction in the cellular energy status will not induce stress protein gene transcription in rainbow trout red blood cells and may, in fact, limit induction during extreme metabolic inhibition.  (+info)

Influence of different types of effectors on the kinetic parameters of suicide inactivation of catalase by hydrogen peroxide. (8/2265)

The effects of cyanide and azide ions (class A), sodium-n-dodecyl sulphate (SDS) and 2-mercaptoethanol (class B), 3-aminotriazole (class C) and NADPH (class D) on the initial activity (ai), inactivation rate constant (ki) and the partition ratio (r) of bovine liver catalase reaction with its suicide substrate, hydrogen peroxide, were studied in 50 mM sodium phosphate buffer, pH 7.0 at 27 degrees C. The above kinetic parameters were determined by processing the progress curve data. In class A, which contains fast and reversible inhibitors of catalase, a proportional decrease in ai and ki was observed by inhibitors, so that the r remained constant. In class B, which contains slow and irreversible inactivators, a decrease in ai and constancy of ki and r were observed when catalase was incubated in the presence of such inactivators for a determined time. In class C, containing effector which can combine with intermediate compound I, ai was relatively unchanged but an increase in ki and a decrease in r were observed. In class D, containing effector which reduces compound I to ferricatalase, ai was not affected significantly but some decrease in ki was detected which was linked with an increase in r. These results demonstrate that different classes of effectors affect the determined kinetic parameters of catalase in various ways. Thus, determination of such parameters by simple kinetic experiments can be carried out for classification of the agents which have an effect on the kinetics of catalase.  (+info)

*Azide

Heavy metal azides, such as lead azide are primary high explosives detonable when heated or shaken. Heavy-metal azides are ... Aryl azides may be prepared by displacement of the appropriate diazonium salt with sodium azide, or trimethylsilyl azide; ... Some azides are valuable as bioorthogonal chemical reporters. Azides are explosophores and toxins. Sodium azide is toxic (LD50 ... The principal source of the azide moiety is sodium azide. As a pseudohalogen compound, sodium azide generally displaces an ...

*Sodium azide

... is a versatile precursor to other inorganic azide compounds, e.g., lead azide and silver azide, which are used in ... The azide anion is very similar in each form, being centrosymmetric with N-N distances of 1.18 Å. The Na+ ion has octahedral ... Sodium azide has caused deaths for decades. It is a severe poison. It possesses the NFPA 704's highest rating of 4 on the heath ... Each azide is linked to six Na+ centers, with three Na-N bonds to each terminal nitrogen center. The common synthesis method is ...

*Trimethylsilyl azide

... ((CH3)3SiN3) is a chemical compound used as a reagent in organic chemistry. Trimethylsilyl azide is ... Trimethylsilyl azide is incompatible with moisture, strong oxidizing agents, and strong acids. L. Birkofer and P. Wegner (1988 ... "Trimethylsilyl azide". Organic Syntheses. ; Collective Volume, 6, p. 1030 Jafarzadeh, Mohammad (2007). "Trimethylsilyl Azide ( ... It may be prepared by the reaction of trimethylsilyl chloride and sodium azide: TMSCl + NaN3 → TMSN3 + NaCl (TMS = (CH3)3Si) It ...

*Cyanogen azide

... , N3CN or CN4, is an azide compound of carbon and nitrogen which is an oily, colourless liquid at room ... "Cycloaddition of sulfonyl azides and cyanogen azide to enamines. Quantum-chemical calculations concerning the spontaneous ... It can be synthesised at below room temperature from the reaction of sodium azide with either cyanogen chloride or cyanogen ... Extremely dangerous outside dilute solution, cyanogen azide has nonetheless been prepared in situ for use in the synthesis of ...

*Phenyl azide

For example, phenyl azide and phenylacetylene give diphenyl triazole. As with many other azides, phenyl azide poses a risk of ... Phenyl azide is an organic compound with the formula C6H5N3. It is one of the prototypical organic azides. It has a pungent ... Phenyl azide and its analogues undergo the azide alkyne Huisgen cycloaddition, a classic example of click chemistry. ... The structure consists of a linear azide substituent bound to a phenyl group. The C−N=N angle is approximately 120°. Phenyl ...

*Methyl azide

... is a covalent molecule related to hydrazoic acid and other alkyl azides. It can be prepared by a methylation of ... Methyl azide is stable at ambient temperature but may explode when heated. Presence of mercury increases the sensitivity to ... Quinto-Hernandez, A.; Wodtke, A. M.; Bennett, C. J.; Kim, Y. S.; Kaiser, R. I. (2011). "On the Interaction of Methyl Azide ( ... Graner, G.; Hirota, E.; Iijima, T.; Kuchitsu, K.; Ramsay, D. A.; Vogt, J.; Vogt, N. "CH3N3 Methyl azide". In Kuchitsu, K. Group ...

*Acyl azide

Acyl azides are used as chemical reagents. On Curtius rearrangement acyl azides yield isocyanates. Acyl azides are also formed ... Alkyl or aryl acyl chlorides react with sodium azide to give acyl azides. They can also be synthesized from various carboxylic ... Another route starts with aliphatic and aromatic aldehydes reacting with iodine azide which is formed from sodium azide and ... Hydrazide und Azide organischer Säuren I. Abhandlung". J. Prakt. Chem. (in German). 50 (1): 275-294. doi:10.1002/prac. ...

*Chlorine azide

Frierson, W. J.; Browne, A. W. (1943). "Chlorine Azide. II. Interaction of Chlorine Azide and Silver Azide. Azino Silver ... Chlorine azide is prepared by passing chlorine gas over silver azide, or by an addition of acetic acid to a solution of sodium ... Chlorine azide reacts explosively with 1,3-butadiene, ethane, ethene, methane, propane, phosphorus, silver azide, and sodium. ... Chlorine azide (ClN3) is an inorganic compound that was discovered in 1908 by Friedrich Raschig. Concentrated ClN 3 is ...

*Diphenylphosphoryl azide

Tosyl azide Trifluoromethanesulfonyl azide R. J. W. Cremlyn (1973). "Some Reactions of O,O-Diphenylphosporyl Azide". Australian ... Diphenylphosphoryl azide (DPPA; alternative, more precise name: diphenoxyphosphoryl azide; IUPAC name: diphenyl phosphorazidate ... with expulsion of the azide ion. The latter then attacks the carbonyl carbon atom, to give the acyl azide and loss of the ... Finally, the acyl azide reacts in the normal manner to give the urethane. Studies show that DPPA reacts with amines giving the ...

*Trifluoromethanesulfonyl azide

... or triflyl azide is an organic azide used as a reagent in organic synthesis. ... Tosyl azide Diphenylphosphoryl azide C. J. Cavender & V. J. Shiner (1972). "Trifluoromethanesulfonyl azide. Its reaction with ... Trifluoromethanesulfonyl azide generally converts amines to azides. Trifluoromethanesulfonyl azide may be formed in situ from ... Trifluoromethanesulfonyl azide is not commercially available. It is prepared before use by reacting trifluoromethanesulfonic ...

*Calcium azide

... is sensitive to impact, in which it may detonate and ignite. Calcium azide at Chemister. ... Calcium azide is a chemical compound with the formula CaN6. It can be obtained from a distilled reaction between hydrazoic acid ...

*Thallium azide

... can be prepared treating an aqueous solution of thallium(I) sulfate with sodium azide. Thallium azide will ... The azide is bound to eight cations in an eclipsed orientation. The cations are bound to eight terminal N centers. All thallium ... Thallium azide, TlN3, is a yellow-brown crystalline solid poorly soluble in water. Although it is not nearly as sensitive to ... Mauer F.A.; Hubbard C.R.; Hahn T.A. (1973). "Thermal expansion and low temperature phase transition of thallous azide". J. Chem ...

*Ammonium azide

... contains about 93% nitrogen by weight as ammonium cation and azide anion. It is a structural isomer of tetrazene ... It was first obtained by Theodor Curtius in 1890, along with other azides. Ammonium azide is ionic. It is scarcely soluble in ... Ammonium azide is the chemical compound with the formula NH4N3, being the salt of ammonia and hydrazoic acid. Like other ... Salim de Amorim, Helio; do Amaral, M. R.; Pattison P.; Ludka I. P.; Mendes, J. C. (2002). "Ammonium azide: A Commented Example ...

*Lithium azide

... sodium azide (NaN3), and lead azide [Pb(N3)2]". International Journal of Quantum Chemistry. 63 (3): 615. doi:10.1002/(SICI)1097 ... Lithium azide is the lithium salt of hydrazoic acid. It is an unstable and toxic compound that decomposes into lithium and ... It can be prepared by metathesis reaction between sodium azide and lithium nitrate: NaN3 + LiNO3 → LiN3 + NaNO3 or lithium ... Younk, Edward H.; Kunz, A. Barry (1997). "An ab initio investigation of the electronic structure of lithium azide (LiN3), ...

*Barium azide

... Ba(N3)2 is an inorganic azide, is explosive, but less sensitive to mechanical shock than lead azide. Can be used ... 1977). Physics and Chemistry of the Inorganic Azides. Energetic Materials. 1. New York and London: Plenum Press. doi:10.1002/ ... Tiede, Erich (1916). "Die Zersetzung der Alkali- und Erdalkali-azide im Hochvakuum zur Reindarstellung von Stickstoff". Ber. ... to make azides of magnesium (but its hydrolytic tendency frustrated efforts to isolate it), sodium, potassium, lithium, ...

*Bromine azide

... may be prepared by the reaction of sodium azide with Br2. This reaction forms bromine azide and sodium bromide: ... Similar samples with azide molecules did not show such an effect. This shows bromine azide's unstable tendencies in that even ... Photochemistry experiments with bromine azide have found that UV photolysis of a small sample of bromine azide resulted in ... Bromine azide is an explosive inorganic compound with the formula BrN3. It has been described as a crystal or a red liquid at ...

*Beryllium azide

... , Be(N3)2, is an inorganic compound. Beryllium azide has been synthesised by the reaction of beryllium chloride ... Wiberg, E.; Horst, M. (1954). "Beryllium azide, Be(N3)2". Zeitschrift für Naturforschung B. 9: 502. "NIOSH Pocket Guide to ... 2CH4 Beryllium azide is predicted to consist of infinite chains, with tetrahedrally coordinated Be2+ ions linked by end-on ... "Synthesis and spectroscopic characterization of beryllium azide and two derivatives". Main Group Metal Chemistry. 22 (6): 357- ...

*Ethyl azide

Molecular Structure and Ionization Energies of Azides: An ab initio Study of Hydrazoic Acid, Methyl Azide and Ethyl Azide". ... Ethyl azide is used for organic synthesis. Campbell, H. C.; Rice, O. K. (1935). "The Explosion of Ethyl Azide". Journal of the ... Ethyl azide (C2H5N3) is an explosive compound sensitive to rapid heating, shock or impact. It has exploded when heated to room ... Rice, O. K.; Campbell, H. C. (1939). "The Explosion of Ethyl Azide in the Presence of Diethyl Ether". The Journal of Chemical ...

*Potassium azide

Like sodium azide, potassium azide is very toxic. The TLV of the related sodium azide is 0.07 ppm. The toxicity of azides arise ... Potassium azide is the inorganic compound having the formula KN 3. It is a white, water-soluble salt. It is used as a reagent ... The azide is bound to eight cations in an eclipsed orientation. The cations are bound to eight terminal N centers. KN3 is ... The decomposition temperatures of the alkali metal azides are: NaN3 (275 °C), KN3 (355 °C), RbN3 (395 °C), CsN3 (390 °C). ...

*Tributyltin azide

... tributyltin azide has been replaced by the less toxic trioctyltin azide and organoaluminium azides. Lower alkyl tin compounds ... Tributyltin azide is an organotin compound. It is usually synthesized from tributyltin chloride and sodium azide. Tributyltin ... Tri-higher alkyl tin azide and its use, United States Patent 5484955 Saito, S (1989). "Highly nucleophilic tributyltin azide in ... Tributyltin azide has a penetrating odor, which is readily absorbed by other materials, for example, clothes of workers, ...

*Silver azide

... can be prepared by treating an aqueous solution of silver nitrate with sodium azide. The silver azide precipitates ... Pure silver azide explodes at 340 °C, but the presence of impurities lowers this down to 270 °C. This reaction has a lower ... Silver azide is the chemical compound with the formula AgN3. This colorless solid is a well-known explosive. ... Correspondingly, each end of each azide ligand is connected to a pair of Ag+ centers. The structure consists of two-dimensional ...

*Tosyl azide

... can be prepared by the reaction of tosyl chloride with sodium azide in aqueous acetone. Tosyl Azide is one of the ... Tosyl azide is a reagent used in organic synthesis. Tosyl azide is used for the introduction of azide and diazo functional ... Diphenylphosphoryl azide Trifluoromethanesulfonyl azide Heydt, H.; Regitz, M.; Mapp, A. K.; Chen, B. (2008). "p-Toluenesulfonyl ... Curphey, T. J. (1981). "Preparation of p-Toluenesulfonyl Azide. A Cautionary Note". Organic Preparations and Procedures ...

*N-Propyl azide

... is a covalent molecule related to hydrazoic acid and other alkyl azides. n-Propyl azide has been used in the ... Edward J. Kaufmann, Richard C. Thompson (1977). "Reduction of organic azides by chromium(II) in aqueous solution". JACS. 99 (6 ... Stefan Bräse (Editor), Klaus Banert (Co-Editor); Organic Azides: Syntheses and Applications; 2010 John Wiley and Sons; ISBN 978 ...

*Lead(II) azide

Lead azide reacts with copper, zinc, cadmium, or alloys containing these metals to form other azides. For example, copper azide ... Lead azide (Pb(N3)2) is an inorganic compound. More so than other azides, Pb(N 3) 2 is explosive. It is used in detonators to ... Lead azide is prepared by metathesis between sodium azide and lead nitrate. Dextrin can be added to the solution to stabilize ... RD-1333 lead azide (MIL-DTL-46225), a version of lead azide with sodium carboxymethylcellulose as a precipitating agent, was ...

*Copper(II) azide

... is a medium density explosive with the molecular formula Cu(N3)2. Copper azide is very explosive and is too ... Copper azide can be prepared by a metathesis reaction between water-soluble sources of Cu2+ and azide ions. (Spectator ions ...
New redox labelling of DNA by an azido group which can be chemically transformed to nitrophenyltriazole or silenced to phenyltriazole was developed and applied to the electrochemical detection of DNA-protein interactions. 5-(4-Azidophenyl)-2-deoxycytidine and 7-(4-azidophenyl)-7-deaza-2-deoxyadenosine nucleosides were prepared by aqueous-phase Suzuki cross-coupling and converted to nucleoside triphosphates (dNTPs) which served as substrates for incorporation into DNA by DNA polymerase. The azidophenyl-modified nucleotides and azidophenyl-modified DNA gave a strong signal in voltammetric studies, at -0.9 V, due to reduction of the azido function. The Cu-catalyzed click reaction of azidophenyl-modified nucleosides or azidophenyl-modified DNA with 4-nitrophenylacetylene gave nitrophenyl-substituted triazoles, exerting a reduction peak at -0.4 V under voltammetry, whereas the click reaction with phenylacetylene gave electrochemically silent phenyltriazoles. The transformation of the azidophenyl ...
Originally reported by Staudinger and Meyer, azides react readily with triarylphosphines to form the corresponding iminophophoranes. The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method.
Smolinsky, G. and Pryde, G. A. (1971) The chemistry of vinyl azides, in The Azido Group (1971) (ed S. Patai), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470771266.ch10 ...
Define azide. azide synonyms, azide pronunciation, azide translation, English dictionary definition of azide. n. Chemistry The univalent linear group N3, or any compound that contains this group, many of which are explosive. az′i·do′ adj. n 1. any compound...
76444-18-3 - HZEKZNNVGVLXHW-UYYQOESLSA-N - beta-(4-Azidophenyl)adenylyl-(3-5)-uridine 5-diphosphate - Similar structures search, synonyms, formulas, resource links, and other chemical information.
The PEG Azide can potentially be reacted with an acetylene moiety (Click reaction) or an arylphosphinederivative, as part of several Staudinger ligation options (see references). It can also be used as a precursor to the amine function in which it can be transformed via reduction with P(Ph)3 ...
cd80 mouse anti human cd80 azide free | order cd80 mouse anti human cd80 azide free | How to use: cd80 mouse anti human cd80 azide free | support help for cd80 mouse
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A two-stage microreactor continuous flow system allows the handling organic azides safely in small hold-up volumes with immediate conversion in the 2nd microreactor. In the 1st microreactor the azide intermediate is formed by nucleophilic substitution.1 The azide intermediate is submitted to Staudinger hydration with triphenylphosphine in a subsequent 2nd microreactor. Notably, it is possible to work with biphasic systems in microreactors. A phase transfer catalyst moderates the initial reaction with efficient mixing by the microreactor. Production capacity of o-Xylylenediamine (711462) in two subsequent glass microreactors exceeds 1 kg per day with an overall yield of 60%. Work-up and isolation of the potentially hazardous intermediate is completely avoided between reaction steps, saving time, money and offering scale-independent safety levels. back to top ...
How to remove azide from antibody - posted in Immunology: Does anybody know how to remove sodium azide from the comercial antiboy solutions? I know there are two ways: dialyzing or exchanging over a column. Could anyone provide more detailed information? Thank you all!
3-Isoxazolecarbonyl azide,5-(fluoromethyl)-/ACM625120083 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
Gentaur molecular products has all kinds of products like :search , Accu \ Mouse TCR gamma_delta, Clone GL_3, Hamster Mab anti_, azide_free \ ACL7201NA for more molecular products just contact us
Rabbit recombinant monoclonal FOXG1 antibody [EPR18987] - BSA and Azide free. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human.
Rabbit recombinant monoclonal Moesin (phospho T558) antibody [EPR2371(2)] - BSA and Azide free. Validated in WB, IHC and tested in Mouse, Rat, Human.
2-Butenoyl azide, 4-(4-morpholinyl)-4-oxo-3-phenyl- | C14H14N4O3 | CID 71392707 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Anti-Human IL-8 Azide Free: Suitable for Flow Cytometry intra-cytoplamic. Blocks IL-8 induced chemotaxis of human neutrophils
Rabbit Polyclonal Anti-LC3A Antibody - Azide Free. Autophagosome Marker. Validated: WB, IHC-P. Tested Reactivity: Human, Mouse, Rat, and more. 100% Guaranteed.
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14343-69-2 - IVRMZWNICZWHMI-UHFFFAOYSA-N - Azide - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Exinon Black Phenyl Bottile Label - Brandzcoin- phenyl label design ,Exinon Black Phenyl Bottile Label design by BrandzSelective in vivo metabolic cell-labeling-mediated cancer ,Herein we report the design of sugars that can selectively label cancer cells both in vitro and in vivo Specifically, we inhibit the cell-labeling activity of tetraacetyl- N -azidoacetylmannosamine (Ac 4 ManAz) by converting its anomeric acetyl group to a caged ether bond that can be selectively cleaved by cancer-overexpressed enzymes and thus enables the overexpression of azido groups on the . ...
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高い抗原親和性、特異性と安定した品質を兼ね備えたアブカムのウサギ・モノクローナル抗体 RabMAb® ab248287 交差種: Ms,Rat,Hu 適用: WB
3-Azido-3-deoxy-myo-inositol (3-AMI) is a D-3-deoxy-3-substituted myo-inositol derivative and intracellular phosphatidinylinositol signal inhibitor. It was
Evaluation of biofilm formation on novel copper-catalyzed azide-alkyne cycloaddition (CuAAC)-based resins for dental restoratives Journal Article ...
TY - JOUR. T1 - The traceless Staudinger ligation for indirect 18F- radiolabelling. AU - Carroll, Laurence. AU - Boldon, Sophie. AU - Bejot, Romain. AU - Moore, Jane E.. AU - Declerck, Jérôme. AU - Gouverneur, Véronique. PY - 2011/1/1. Y1 - 2011/1/1. N2 - The Staudinger ligation of phosphine-substituted thioesters with 18F-fluoroethylazide has been successfully applied to access 18F-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated.. AB - The Staudinger ligation of phosphine-substituted thioesters with 18F-fluoroethylazide has been successfully applied to access 18F-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated.. UR - http://www.scopus.com/inward/record.url?scp=78650098745&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=78650098745&partnerID=8YFLogxK. U2 - 10.1039/c0ob00564a. DO - ...
Looking for online definition of Azides in the Medical Dictionary? Azides explanation free. What is Azides? Meaning of Azides medical term. What does Azides mean?
Photo-activation of the hydrophobic membrane probe 1, 5 iodonaphthylazide (INA) by irradiation with UV light (310-380 nm) results in the covalent modification of transmembrane anchors of membrane proteins. This unique selectivity of INA towards the transmembrane anchor has been exploited to specifically label proteins inserted in membranes. Previously, we have demonstrated that photo-activation of INA in enveloped viruses resulted in the inhibition of viral membrane protein-induced membrane fusion and viral entry into cells. In this study we show that photo-activation of INA in various cell lines, including those over-expressing the multi-drug resistance transporters MRP1 or Pgp, leads to cell death. We analyzed mechanisms of cell killing by INA-UV treatment. The effects of INA-UV treatment on signaling via various cell surface receptors, on the activity of the multi-drug resistance transporter MRP1 and on membrane protein lateral mobility were also investigated. INA treatment of various cell lines
Alfa Aesar™ BLOTTO in PBS, with 0.02% sodium azide 250mL Alfa Aesar™ BLOTTO in PBS, with 0.02% sodium azide Blocking Buffers for Protein Methods
Severn Biotech, Limited PBS (1X) With sodium 0.1% Azide - Phosphate Buffered Saline 1x PBS with 0.1%w/v Sodium Azide. (1X PBS with Azide)This ubiquitous buffer is supplied with the preservative sodium azide already incorporated into the solution. Supplied 0.2 micron filtered in a ready to use format.For use in immunology, molecular biology and other life science techniques as a storage
Find and Shop the largest selection of Click-&-Go Dde Protein Enrichment Kit for Capture and Release of Azide-modified Proteins here at Click Chemistry Tools. Order Now!
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Pegylation using heterotelechelic poly(ethylene glycol) (PEG) offers many possibilities to create high-performance molecules and materials. A versatile route is proposed to synthesize heterobifunctional PEG containing diverse combinations of azide, amine, thioacetate, thiol, pyridyl disulfide, as well as activated hydroxyl end groups. Asymmetric activation of one hydroxyl end group enables the heterobifunctionalization while applying selective monotosylation of linear, symmetrical PEG as a key step. The azide function is introduced by reacting monotosyl PEG with sodium azide. A thiol end group is obtained by reaction with sodium hydrosulfide. The activation of the hydroxyl end group and subsequent reaction with potassium carbonate/thioacetic acid yields a thioacetate end group. The hydrolysis of the thioester end group by ammonia in presence of 2,2′-dipyridyl disulfide provides PEG pyridyl disulfide. Amine terminated PEG is prepared either by reduction of the azide or by nucleophilic substitution of
Thanks Nick, this is exactly the kind of thing we should get from the safety officer, so that we can use these compounds safely. Rather than dopy comments like 1ml of 0.02% sodium azide is an explosive hazard. Mike. On Wed, 18 Jul 2001, Nick Theodorakis wrote: , In , ,Pine.SGI.4.33.0107182118570.2615940-100000 at mole.bio.cam.ac.uk,, , Michael Witty wrote: , , , ,On Wed, 18 Jul 2001, Warren Gallin wrote: , ,, So if you are flushing azide down a sink with metal plumbing, over a , ,, period of time a nasty explosive will build up in the traps. The poor , ,, plumber who cracks one of them can have a small grenade going off , in , ,, his/her face. This has actually happened, so not a theoretical , ,, consideration at all. , , , ,Dear Warren, , , please let me know about the paper or news report that has , ,described these two kinds of accident. I really am interested in , ,collecting examples of this kind of thing happening. , ,Mike. , , , , This is the closest thing I could find: , , ...
AIM: To investigate the neuroprotective effects of hyperoside (Hyp) on PC12 cells apoptosis induced by sodium azide and the mechanism of action. METHODS: To induce apoptosis, cultured PC12 cells was incubated with sodium azide 20 mmol·L⁻¹ for 3-24 h. Pretreatment with Hyp (0.01, 0.1 or 1 μmol·L⁻¹) for 4 h before sodium azide treatment. Cell viability was measured by MTT assay. The chromatin-specif ...
sample_1: JARID1C, [U-100% 15N], 1 mM; sodium phosphate 50 mM; sodium chloride 50 mM; sodium azide 0.02%; DTT 5 mM. sample_2: JARID1C, [U-13C; U-15N], 1 mM; sodium phosphate 50 mM; sodium chloride 50 mM; sodium azide 0.02%; DTT 5 mM. sample_3: JARID1C, [U-100% 15N], 1 mM; sodium phosphate 50 mM; sodium chloride 50 mM; sodium azide 0.02%; DTT 5 mM. sample_4: JARID1C, [U-13C; U-15N], 1 mM; sodium phosphate 50 mM; sodium chloride 50 mM; sodium azide 0.02%; DTT 5 mM. sample_conditions_1: pH: 6.0; pressure: 1 atm; temperature: 297 K. sample_conditions_2: pH*: 6.0; pressure: 1 atm; temperature: 297 K ...
sample_1: Get5 1 mM; Sgt2, [U-100% 13C; U-100% 15N], 2 mM; Bis-Tris 10 mM; L-arginine 50 mM; L-glutamic acid 50 mM; sodium azide 0.02%; H2O 90%; D2O 10%. sample_2: Get5 1 mM; Sgt2, [U-100% 13C; U-100% 15N], 2 mM; Bis-Tris 10 mM; L-arginine 50 mM; L-glutamic acid 50 mM; sodium azide 0.02%; polyacrylamide 3.5%; H2O 90%; D2O 10%. sample_3: Get5, [U-100% 13C; U-100% 15N], 1 mM; Sgt2 2 mM; Bis-Tris 10 mM; L-arginine 50 mM; L-glutamic acid 50 mM; sodium azide 0.02%; H2O 90%; D2O 10%. sample_4: Get5, [U-100% 13C; U-100% 15N], 1 mM; Sgt2 2 mM; Bis-Tris 10 mM; L-arginine 50 mM; L-glutamic acid 50 mM; sodium azide 0.02%; polyacrylamide 3.5%; H2O 90%; D2O 10%. sample_conditions_1: ionic strength: 0 mM; pH: 6.1; pressure: 1 atm; temperature: 310 K ...
[65 Pages Report] Check for Discount on Sodium azide Global Market and Forecast Research report by ChemReport. DescriptionWe provide independent and unbiased information on manufacturers, prices, production...
Azido azetikoa konposatu organiko bat da. Formula kimiko hau du: CH3-COOH (C2H4O2).. Kolorerik gabeko likidoa da. Azido azetikoa ozpinaren osagai nagusia da. Azido ahultzat sailkatzen den arren, kontzentrazio altuetan korrosiboa da, eta gizakiaren larruazalari kalte egin diezaioke.. Azido azetiko sinpleena azido karboxilikoa da. Konposatu garrantzitsua da erreaktiboetan eta industria kimikoan, batez ere zeluloide azetatoa, argazki filma eta polibinil azetatoa ekoizteko. Zuntz sintetikoetan ere erabil daiteke. Etxebizitzetan, diluituta erabiltzen da. Kaltzioa kentzeko (E260) azidotasun erregulatzailetzat eta ongailutzat erabiltzen da.. ...
Tetranitrogen is a neutrally charged polynitrogen allotrope of the chemical formula N 4 and consists of four nitrogen atoms. The tetranitrogen cation is the positively charged ion, N+ 4, which is more stable than the neutral tetranitrogen and is thus more studied. The structure, stability and properties of these molecules have been of great interest to research scientists in the last ten years.[when?] Polynitrogen compounds have been well known and characterized by chemists for many years. Molecular nitrogen (N 2) was first isolated by Daniel Rutherford in 1772 and the azide ion (N− 3) was discovered by Theodor Curtius in 1890. Discoveries of other related nitrogenous allotypes during the twentieth century include the aromatic molecule pentazole and the radical molecule N• 3. However, none of these complexes could be isolated or synthesized on a macroscopic scale like N 2 and azide; it was not until 1999 that a large scale synthesis was devised for a third nitrogen allotrope, the pentazenium ...
The synthesis and full characterisation of bifunctional β -amino acids that have side chains functionalised with terminal azides (S)-4 and (R)-4 or acetylenes 5 and 6 is reported for the first time. The building blocks incorporate a turn-inducing β -segment and a side chain that can be functionalised further, for example, through copper-catalysed Huisgen cycloaddition. Moreover, the corresponding α-amino acids 1 and 3 have been synthesised and characterised. All amino acid building blocks were of high optical purity as demonstrated by derivatisation and subsequent NMR analysis ...
Nota lepid. 36 (1): The status of Satyrus abramovi var. korlana Staudinger, 1901 (Nymphalidae) StaniSlav K. Korb a/ya 97, Nizhny Novgorod Russia; Received 14 August
Benzoyl azide solution/AFI582616 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
EXPERIMENTAL. The above experiments was conducted on a C80 at a heating rate of 0,5 K/min between room temperature and 280 °C. 76 mg of sample where placed inside a glass liner perfectly fitting the C80 high pressure measurement cell. The C80 was then cooled down, and the permanent decomposition gases were sent to a gas analyzer cell (FTIR).. RESULTS AND CONCLUSIONS. The complex two-step decomposition of o-trifluoromethyl phenyl azide was studied thanks to a combination of calorimetric, pressure, and evolved gas analysis data. Not only thermal and pressure hazards can be assessed, but also the risks linked with the formation of toxic gases - or straightforward information about decomposition mechanisms. For example, the strange silane - based gas detected by the FTIR was assigned to a reaction between the sample and the glass liner.. ...
Mouse Monoclonal Anti-Mucin 5AC Antibody (45M1) - Azide and BSA Free. Validated: WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP, CyTOF-ready. Tested Reactivity: Human, Mouse, Rat, and more. 100% Guaranteed.
TIM-3 antibody [RMT3-23] (Low endotoxin, azide free) (hepatitis A virus cellular receptor 2) for FACS, ICC/IF, IHC-Fr, IHC-P, Functional Assay. Anti-TIM-3 mAb (GTX54054) is tested in Mouse samples. 100% Ab-Assurance.
PMA is a high affinity photoreactive DNA binding dye developed by Biotium. The dye is weakly fluorescent by itself but becomes highly fluorescent upon binding to nucleic acids. It preferentially binds to dsDNA with high affinity. Upon photolysis, the photoreactive azido group on the dye is converted to a highly reactive nitrene radical, which readily reacts with any hydrocarbon moiety at the binding site to form a stable covalent nitrogen-carbon bond, thus resulting in permanent DNA modification. The dye is cell membrane-impermeable and thus can be used to selectively modify DNA from dead cells with compromised membrane integrity, while leaving DNA from viable cells intact. PMA inhibits PCR amplification of modified DNA templates by a combination of removal of modified DNA during purification and inhibition of template amplification by DNA polymerases (see Reference 1 under the references tab). Consequently the dye is useful in the selective detection of viable pathogenic cells by quantitative ...
Azido maliko (HO2CCH2CHOHCO2H) landare eta fruitu ugaritan -sagar berdeetan, batik bat- izaten den bi azidodun alkohola da. Landareen eta animalien zelulen metabolismoan parte hartzen du. 100 °C-tan urtzen diren kristalak eratzen ditu, eta uretan eta alkoholean urtzen da. Sintesiz ere lor daiteke, azido maleikoa berotuz, edo azido tartarikotik, sukzinikotik eta aspartikotik.. ...
Rabbit ,200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.AB2, 36-3502
Mouse ,200µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.,AB2
The lead that is a worry at shooting ranges is lead azide. Azides are shock-sensitive explosives that are used in primers, the little round bit of the cartridge that the firing pin hits. They set fire to the gunpowder. Theres various formulas for the things; one of them includes lead. In burning, of course, a lot of it winds up as smoke, which can be inhaled. Then your body winds up dealing with it the same way it does with any other heavy-metal toxin: it will damage pretty much everything. Yall have to breathe in a lot of the crap to do this, though. I only know of a single lead azide fatality, a State Police firing range instructor back in the nineties who went to bed one night and didnt wake up in the morning. Since then pretty much every indoor shooting range has put in much larger exhaust fans ...
The lead that is a worry at shooting ranges is lead azide. Azides are shock-sensitive explosives that are used in primers, the little round bit of the cartridge that the firing pin hits. They set fire to the gunpowder. Theres various formulas for the things; one of them includes lead. In burning, of course, a lot of it winds up as smoke, which can be inhaled. Then your body winds up dealing with it the same way it does with any other heavy-metal toxin: it will damage pretty much everything. Yall have to breathe in a lot of the crap to do this, though. I only know of a single lead azide fatality, a State Police firing range instructor back in the nineties who went to bed one night and didnt wake up in the morning. Since then pretty much every indoor shooting range has put in much larger exhaust fans ...
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Guannan East Chemical Co., Ltd. (the original Yizheng East Chemical Co., Ltd.) is a comprehensive chemical enterprise engaged in researching, developing, manufacturing, and marketing pesticide, pharmaceutical and electronic intermediates.
Concentration Unitmg/mLConcentration1Quantity0.1 mgVolume0.1ImmunogenHuman Acute Lymphocytic Leukemia (ALL) T cellsBackground InformationCD46 (MCP;...
Concentration Unitmg/mLConcentration1Quantity0.1 mgVolume0.1ImmunogenRaji cells and spleen cells fused with NS1 cellsBackground InformationCD54 (IC...
Bio-Rad Antibodies (formerly AbD Serotec) is the research antibody division of Bio-Rad, the worlds leading life science company.
The IUPHAR/BPS Guide to Pharmacology. [125I]7-azido-8-iodoketanserine ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs.
Browse many computed properties for this monoclinic H9CN9 compound, including formation energy from the elements, energy of decomposition into the set of most stable materials at this chemical composition, bulk crystalline density, and band gap. Also known as: Triaminoguanidinium azide. Cite this material using DOI 10.17188/1202729.
100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use ...
200 µl purified IgY, lyophilized. Ovalbumin and azide was added for stabilization. For reconstitution add 200 µl H2O. Then aliquot and store at -20°C until use. Before storing at -20°C add 1 vol of glycerol. ...
for b) and c) you want to provide everything but the missing gene, so only those that have acquired the gene will grow, but you need to select against the donor too, so you need to use an antimicrobial to kill it too (ie str or azide ...
for b) and c) you want to provide everything but the missing gene, so only those that have acquired the gene will grow, but you need to select against the donor too, so you need to use an antimicrobial to kill it too (ie str or azide ...
LI-COR now offers a portfolio of Click Chemistry reagents for copper-catalyzed and copper-free methods. These products offer researchers flexibility to choose the correct reagent for a diverse array of applications. LI-COR Click Chemistry reagents include IRDye® 800CW, IRDye 680RD, and IRDye 650 infrared fluorescent dyes labeled with DBCO, azide, or alkyne groups. Click Chemistry utilizes pairs of reagents that exclusively react with each other and are effectively inert to naturally-occurring functional groups such as amines. Unlike affinity interactions such as streptavidin-biotin, Click Chemistry forges covalent bonds between the reacting partners to deliver stable bioconjugates.. Click Chemistry reactions can be categorized into two separate groups, copper-catalyzed or copper-free. Copper-catalyzed Click Chemistry is used for initiating reactions between azides and alkynes. These reactions are also known as Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC). Although they initiate and ...
LI-COR now offers a portfolio of Click Chemistry reagents for copper-catalyzed and copper-free methods. These products offer researchers flexibility to choose the correct reagent for a diverse array of applications. LI-COR Click Chemistry reagents include IRDye® 800CW, IRDye 680RD, and IRDye 650 infrared fluorescent dyes labeled with DBCO, azide, or alkyne groups. Click Chemistry utilizes pairs of reagents that exclusively react with each other and are effectively inert to naturally-occurring functional groups such as amines. Unlike affinity interactions such as streptavidin-biotin, Click Chemistry forges covalent bonds between the reacting partners to deliver stable bioconjugates.. Click Chemistry reactions can be categorized into two separate groups, copper-catalyzed or copper-free. Copper-catalyzed Click Chemistry is used for initiating reactions between azides and alkynes. These reactions are also known as Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC). Although they initiate and ...
0018] Compounds of formula (I) and (III) wherein the vector is a peptide or protein may be prepared by standard methods of peptide synthesis, for example, solid-phase peptide synthesis, for example, as described in Atherton, E. and Sheppard, R. C.; "Solid Phase Synthesis"; IRL Press: Oxford, 1989. Incorporation of the alkyne or azide group in a compound of formula (I) or (III) may be achieved by reaction of the N or C-terminus of the peptide or with some other functional group contained within the peptide sequence, modification of which does not affect the binding characteristics of the vector. The alkyne or azide groups are preferably introduced to a compound of formula (I) or (III) by formation of a stable amide bond, for example formed by reaction of a peptide amine function with an activated acid or alternatively reaction of a peptide acid function with an amine function and introduced either during or following the peptide synthesis. Methods for incorporation of the alkyne or azide group ...
Biomedical sciences, and in particular biomarker research, demand efficient glycoprotein enrichment platforms. In this paper, a facile and efficient approach combining distillation-precipitation polymerization (DPP) and click chemistry was developed to synthesize boronic acid ligand-modified magnetic nanoparticles for the enrichment of glycoproteins. Due to the relatively large amount of benzyl chloride groups introduced by DPP on the magnetic core, which easily can be transferred into azide groups, the alkyne-phenylboronic acid ligands were immobilized onto the surface of Fe3O4 with high efficiency via the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click reaction. The morphology, structure and composition of the resulting core-shell [email protected](4-vinylbenylchloride)@amidophenylboronic acid ([email protected]@APBA) nanocomposites were characterized by transmission electron microscopy, X-ray powder diffraction, vibrating sample magnetometry, Fourier transform infrared spectroscopy, ...
A. C. Cardiel, M. C. Benson, L. M. Bishop, K. M. Louis, J. C. Yeager, Y. Tan, R. J. Hamers. "Chemically Directed Assembly of Photoactive Metal Oxide Nanoparticle Heterojunctions via the Copper-Catalyzed Azide-Alkyne Cycloaddition "Click" Reaction." ACS Nano 2012, 6, 310-318. This article was also featured in C&EN on Jan. 23, 2012 in the News of the Week section (Volume 90, Issue 4, p. 8).. ...
The National Institute for Occupational Safety and Health (NIOSH) is alerting you to an explosive hazard which may exist in hospital and clinical laboratory plumbing systems due to sodium azide formulated into diluents used in conjunction with automatic blood cell counters. These counters are found in over 15,000 hospitals and clinical laboratories throughout the United States.. NIOSH has recently learned of violent sodium azide-related explosions associated with automatic blood cell counters at a number of hospitals in the United States and Canada. In addition, we are aware of a violent azide explosion occurring while a constant temperature water bath in which sodium azide had been used as a preservative was being repaired. These explosions have the propensity to propel metallic fragments over a wide area and the potential for causing serious injury to exposed workers and others in the vicinity.. Sodium azide is a common preservative in many in vitro diagnostic products and is found in ...
Buy Photoaffinity Labels from Santa Cruz. View and select products within our Photoaffinity Labels category available for immediate purchase.
sample_15N_H2O: Fyn SH3 A39V/N53P/V55L, [U-15N], 0.7 mM; EDTA 0.2 mM; sodium azide 0.05%; potassium phosphate 50 mM; H2O 90%; D2O 10%. sample_15N2H_H2O: Fyn SH3 A39V/N53P/V55L, [U-15N; U-2H], 1.0 mM; EDTA 0.2 mM; sodium azide 0.05%; potassium phosphate 50 mM; H2O 90%; D2O 10%. sample_15N2H_H2O_Pf1: Fyn SH3 A39V/N53P/V55L, [U-15N; U-2H], 0.8 mM; EDTA 0.2 mM; sodium azide 0.05%; potassium phosphate 50 mM; Pf1 phage 24 mg/ml; H2O 90%; D2O 10%. sample_15N2H_H2O_PEG: Fyn SH3 A39V/N53P/V55L, [U-15N; U-2H], 0.5 mM; EDTA 0.2 mM; sodium azide 0.05%; potassium phosphate 50 mM; PEG/hexanol uncertain v/v; H2O 90%; D2O 10%. sample_13C15N2H_H2O: Fyn SH3 A39V/N53P/V55L, [U-13C; U-15N; U-2H], 1.2 mM; EDTA 0.2 mM; sodium azide 0.05%; potassium phosphate 50 mM; H2O 90%; D2O 10%. sample_13C15N2H_H2O_Pf1: Fyn SH3 A39V/N53P/V55L, [U-13C; U-15N; U-2H], 0.8 mM; EDTA 0.2 mM; sodium azide 0.05%; potassium phosphate 50 mM; Pf1 phage 36 mg/ml; H2O 90%; D2O 10%. sample_13C15N50%2H_H2O: Fyn SH3 A39V/N53P/V55L, [U-13C; ...
Green-emitting, azide activated fluorescent probes used for detection alkyne-containing targers via a copper-catalyzed click reaction (CuAAC).
en] Oligonucleotides (ONs) and more particularly siRNAs are promising drugs but their pharmacokinetics and biodistribution are widely unknown. Positron Emission Tomography (PET) using fluorine-18 is a suitable technique to quantify these biological processes. Click chemistry (Huisgen cycloaddition) is the current method for labeling siRNA. In order to study the influence of a linker bearing by [18F]labeled ONs, on the in vivo pharmacokinetic and metabolism, we have developed two modified ONs by two news linkers. Here we report the synthesis of two alkyne-bearing linkers, the incorporation onto a ONs and the conjugation by click chemistry with a [18F]prosthetic group ...
2′-Deoxynucleoside conjugates of 13α-estrone were synthesized by applying the copper-catalyzed alkyne-azide click reaction (CuAAC). For the introduction of the azido group the 5′-position of the nucleosides and a propargyl ether functional group on the 3-hydroxy group of 13α-estrone were chosen. The best yields were realized in our hands when the 3′-hydroxy groups of the nucleosides were protected by acetyl groups and the 5′-hydroxy groups were modified by the tosyl-azide exchange method. The commonly used conditions for click reaction between the protected-5′-azidonucleosides and the steroid alkyne was slightly modified by using 1.5 equivalent of Cu(I) catalyst. All the prepared conjugates were evaluated in vitro by means of MTT assays for antiproliferative activity against a panel of human adherent cell lines (HeLa, MCF-7 and A2780) and the potential inhibitory activity of the new conjugates on human 17β-hydroxysteroid dehydrogenase 1 (17β-HSD1) was investigated via in vitro
Conference Paper: Ruthenium(IV) Porphyrin Catalyzed Nitrene Insertion to sp3 and sp2 C‐H Bond Using Phosphoryl Azides as Nitrene ...
Research Topics, Species, Genomes and Genes, Research Grants, Publications about Recombinant and Chemo-/Bio-Orthogonal Synthesis of Liposomal Thrombomodulin
QUINOLINE-5-CARBONYL AZIDE,CCD编号:CCD03496255,分子式:C10 H6 N4 O,分子量:198.184,同义词:QUINOLINE-5-CARBONYL AZIDE; 分子结构,化学云数据库
For CF® dye, cyanine dye, FITC, biotin, DNP, and dig Mix-n-Stain™ kits, sodium azide, EDTA, small sugars, and ,10% glycerol have no effect on the labeling. Higher levels of glycerol, or any level of DTT, 2-mercaptoethanol or free amino acids (such as glycine) should be removed using the ultrafiltration vial provided in the kit. See the Product Protocol for more information.. Note that Mix-n-Stain™ Maxi 1 mg Scale Kits, Mix-n-Stain™ Fluorescent Protein Labeling Kits (R-PE, APC, PerCP, or tandem dye), Mix-n-Stain™ Enzyme Labeling Kits (AP, HRP, GOx) have different compatibility requirements and labeling protocols. Check the protocol for your kit to verify that your antibody is compatible with labeling, then choose a kit size that matches your the amount of antibody you wish to label.. Category: Mix-n-Stain™ Antibody Labeling Kits ...
Close The Infona portal uses cookies, i.e. strings of text saved by a browser on the users device. The portal can access those files and use them to remember the users data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser. ...
Cyclooctyne-based modifications offers the ease of copper-free click reagents. These are simple to use and has excellent click performance in 17 hours or less at room temperature. Gene Link offers 5-DBCO-TEG for preparing oligos with 5 -DBCO and a 15 tom triethylene glycol spacer arm, DBCO-dT for inserting a DBCO group at any position within the oligonucleotide and DBCO-sulfo-NHS Ester is also offered for post-synthesis conjugation reactions. DBCO-modified oligos may be conjugated with azides in organic solvents, such as DMSO, or aqeous buffers. Depending on the azide used, the reaction will go to completion in 4-17 hours at room temperature.. ...
Water-soluble fluorescent dye reacting with alkyne groups. The slight red shift in absorption spectrum makes Fluorescent Dye 647-I Azide an optimal match to filters designed Cy5 dyes.Besides, their fluorescence is pH-independent from pH 3 to 11. (U0252) - Products - Abnova
MUC1 / EMA / CD227 (Epithelial Marker) Antibody - With BSA and Azide, Mouse Monoclonal Antibody [Clone HMPV ] validated in IHC-P, IF, FC (AH11857-20), Abgent
Mitochondria (Marker for Human Cells) Antibody - With BSA and Azide, Purified Mouse Monoclonal Antibody validated in WB, IHC, IF, FC, IP (AH10280-20), Abgent
IL2 Receptor alpha antibody [PC61.5.3] (Low endotoxin, azide free) (interleukin 2 receptor, alpha chain) for FACS, IHC-Fr, IP, Functional Assay. Anti-IL2 Receptor alpha mAb (GTX42209) is tested in Mouse samples. 100% Ab-Assurance.
a Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology, College of Chemistry and Food Science of Yulin Normal University, Yulin 537000 ...
Thermosensitive polymers are a class of "smart" materials that have the ability to respond to a change in temperature. SPECIFIC POLYMERS synthesize a broad array of monomers and polymers of interest in this area ...
|p|The mouse monoclonal antibody recognizes human IL-21, a member of the commongamma chain family of cytokines with immunoregulatory activity. IL-21 plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferati
We are pleased to welcome you to our new website. As a thank you for your continued customer loyalty, all newly registered accounts will receive a complimentary 5% discount.. ...
3-[(6-azido-9H-purin-9-yl)methyl]phenylformamide - chemical structural formula, chemical names, chemical properties, synthesis references
Hopefully the series of posts on the linear algebra underlying the postulates of QM were of some use. They certainly took a lot longer to write than I initially thought. As high school freshmen we read the Canterbury Tales (in translation). My mother, an English major, had to learn old English in order to read…
Description PHF13 Polyclonal Antibody. Unconjugated. Raised in Rabbit. Formulation Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity Human, Mouse, Rat Isotype IgG Uniprot ID Q86YI8 Purification Affinity...
F(ab)2-Rabbit anti-Goat IgG (H+L) Secondary Antibody, TRITC conjugate from Invitrogen for Immunofluorescence applications.This antibody is cross-adsorbed against human, mouse and rat igg. Supplied as 500 µg purified secondary antibody in PBS with 1% BSA and 0.05% sodium azide; pH 7.2.
... Secondary Antibody from Invitrogen for ELISA applications. Supplied as 1 mg purified secondary antibody (4.4 mg/ml) in PBS with 0.09% sodium azide; pH 7.4.
Or, How I Learned to Stop Worrying and Love Sodium Azide. Never eat anything you cant pronounce. - Some sperg on an anti-vaccination, anti-...
Can you pick the numbers from 1-100 described by the clues? Test your knowledge on this miscellaneous quiz to see how you do and compare your score to others. Quiz by wiggytitch
Find more than 1700 high purity PEG linkers with a broad selection of funcitonal groups (amine, azide, maleimide, NHS ester, bromide, etc) to inspire your PEGylation. Order now!
We prepared 1-(4′-azido-2′-deoxy-2′-fluoro-D-arabinofuranosyl)cytosine (10) and its hydrochloride sodium (11) while potential antiviral real estate agents based on the good antiviral information of 4′-substituted nucleosides. (10) (Fig. 1) like a novel potent NRTI that couldovercome drug -resistanceproblems [ 19-21]. Fig. 1 Structures of 1-(4′-Azido-2′-deoxy-2′-fluoro-D-arabinofuranosyl)cytosine (10) and Its Design Lead 4′-Azido-thymidine. 2 Chemistry The synthesis of 10 …Read More. ...
Photo-mediated copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) "click" reactions for forming polymer networks as shape memory materials Journal Article ...
In this work, we confirmed that the copper-catalysed azide-alkyne cycloaddition (CuAAC) reaction is an effective method for the organic-functionalization of polyoxometalates (POMs). Herein, for the first time, four novel 1,2,3-triazole functionalized polyoxovanadate (POV) organic-inorganic hybrids, (Bu4N)2[V6O13{(O
Interdisciplinary Nanoscience Center - INANO-Fysik, iNANO-huset, Interdisciplinary Nanoscience Center, Science and Technology, Aarhus ...
Herein, four new H-shaped triphenylene discotic liquid crystal tetramers have been designed and synthesized using a copper-free [3+2] cycloaddition reaction between the triphenylene dimer and diazide compounds. To probe the molecular self-assembly and mesophase properties, the length and rigid spacers in diazide have been tailored.
In this study, a novel approach was developed to synthesize aminophenylboronic acid functionalized magnetic nanoparticles (NPs) via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry. Firstly, azide-functional Fe3O4 NPs were obtained by a two-step chemical modification process. Then, an alkyne-phenylboronic acid molecule was connected onto the surface of magnetite by the CuAAC reaction. The morphology, structure and composition of the synthesized nanocomposites were characterized by transmission electron microscopy (TEM), X-ray powder diffraction (XRD), vibrating sample magnetometer (VSM), Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectrometry (XPS). Five proteins, including ovalbumin (OB), transferrin (Trf), as glycoprotein templates and lysozyme (Lyz), bovine serum albumin (BSA), horse heart cytochrome c (Cyt C) as nonglycoprotein templates are chosen as target proteins. The as-prepared [email protected] NPs with a mean diameter of 23.2 nm showed a ...
Several studies have demonstrated that the intrinsic catalytic activity of cell surface glucose transporters is highly regulated in 3T3-L1 adipocytes expressing GLUT1 (erythrocyte/brain) and GLUT4 (adipocyte/skeletal muscle) glucose transporter isoforms. For example, inhibition of protein synthesis in these cells by anisomycin or cycloheximide leads to marked increases in hexose transport without a change in the levels of cell surface glucose transporter proteins (Clancy, B. M., Harrison, S. A., Buxton, J. M., and Czech, M. P. (1991) J. Biol. Chem. 266, 10122-10130). In the present work the exofacial hexose binding sites on GLUT1 and GLUT4 in anisomycin-treated 3T3-L1 adipocytes were labeled with the cell-impermeant photoaffinity reagent [2-3H]2-N-[4-(1-azitrifluoroethyl)benzoyl]-1,3-bis- (D-mannos-4-yloxy)-2-propylamine [( 2-3H] ATB-BMPA) to determine which isoform is activated by protein synthetic blockade. As expected, a 15-fold increase in 2-deoxyglucose uptake in response to insulin was associated
TY - JOUR. T1 - Carbene and silicon routes as methods for the generation and dipolar cycloaddition reactions of methyl nitrile ylide. AU - Padwa, Albert. AU - Gasdaska, John R.. AU - Tomas, Miguel. AU - Turro, Nicholas J.. AU - Cha, Yuan. AU - Gould, Ian. PY - 1986. Y1 - 1986. N2 - Methyl nitrile ylide was generated by both a photochemical and desilylation route and has been characterized by UV spectroscopy and by its kinetic and cycloaddition behavior. The dipole is formed by the addition of singlet methylene to acetonitrile and shows a strong transient absorption at 280 nm which is quenched by the addition of standard dipolarophiles. The relative rates of formation of 1,3-dipolar adducts and the relative rates of quenching of the transient absorption are in excellent agreement. Generation of the dipole from a silylthioimidate followed by dipolar cycloaddition also gave rise to related cycloadducts. The ratio of cycloadducts obtained from an unsymmetrically substituted dipolarophile was found ...

CDC | Facts About Sodium AzideCDC | Facts About Sodium Azide

How you could be exposed to sodium azide *Following release of sodium azide into water, you could be exposed to sodium azide by ... Where sodium azide is found and how it is used *Sodium azide is best known as the chemical found in automobile airbags. An ... How sodium azide works *The seriousness of poisoning caused by sodium azide depends on the amount, route, and length of time of ... What sodium azide is *Sodium azide is a rapidly acting, potentially deadly chemical that exists as an odorless white solid. ...
more infohttps://emergency.cdc.gov/agent/sodiumazide/basics/facts.asp

hydrogen azide (CHEBI:29449)hydrogen azide (CHEBI:29449)

... is a nitrogen hydride (CHEBI:35106) hydrogen azide (CHEBI:29449) is conjugate acid of azide anion ... azide anion (CHEBI:40910) is conjugate base of hydrogen azide (CHEBI:29449). ... CHEBI:29449 - hydrogen azide. Main. ChEBI Ontology. Automatic Xrefs. Reactions. Pathways. Models. ...
more infohttps://www.ebi.ac.uk/chebi/searchId.do?chebiId=29449

SODIUM AZIDESODIUM AZIDE

... MSDS Number: S2906 --- Effective Date: 03/18/98. 1. Product Identification. Synonyms: Azide; Azium; Smite CAS No ... Proper Shipping Name: SODIUM AZIDE Hazard Class: 6.1 UN/NA: UN1687 Packing Group: II Information reported for product/size: 5KG ... Proper Shipping Name: SODIUM AZIDE Hazard Class: 6.1 UN/NA: UN1687 Packing Group: II Information reported for product/size: 5KG ... Sodium Azide (26628-22-8) Yes Yes No Yes --------\Federal, State & International Regulations - Part 1\---------------- -SARA ...
more infohttps://hazard.com/msds/mf/baker/baker/files/s2906.htm

sodium azidesodium azide

... leschnitzrd at buvax1.baylor.edu leschnitzrd at buvax1.baylor.edu Wed Mar 17 10:03:11 EST 1993 *Previous message ... We are having some arguments about the concentration of sodium azide to use in sandwich box reservoirs containing PEG or in ...
more infohttp://www.bio.net/bionet/mm/xtal-log/1993-March/000196.html

CDC | Case Definition: Sodium AzideCDC | Case Definition: Sodium Azide

The majority of exposures to sodium azide occur by inhalation. Signs and symptoms of sodium azide poisoning include lethargy or ... Biologic: A case in which sodium azide in serum is detected, as determined by a commercial laboratory. ... Environmental: Detection of sodium azide in environmental samples, as determined by FDA. ... exists for sodium azide exposure, or an epidemiologic link exists between this case and a laboratory-confirmed case. ...
more infohttps://emergency.cdc.gov/agent/sodiumazide/basics/casedef.asp

Federal Register
       :: 
      Sodium Azide From JapanFederal Register :: Sodium Azide From Japan

... the Department of Commerce published notice of the suspension of its antidumping investigation on sodium azide from Japan (62 ... Sodium Azide From Japan. A Notice by the International Trade Commission on 01/15/1997. ...
more infohttps://www.federalregister.gov/documents/1997/01/15/97-970/sodium-azide-from-japan

FltPlan.com NavAid Info AZIDEFltPlan.com NavAid Info AZIDE

Identifier: AZIDE. Lat/Long: 33-12-09.820N / 097-07-19.220W. State Name: TEXAS. Fix Category: Civil. Fix Use: RNAV-WP. ARTCC: ZFW. Pitch: No. Catch: No. Charts: SID. ...
more infohttp://www.fltplan.com/fix/AZIDE.htm

Ames test: Ethidium bromide: azideAmes test: Ethidium bromide: azide

These incidents seem to happen with relatively large amounts of azide in , use. , , Note also, however, that even sodium azide ... Ames test: Ethidium bromide: azide. Michael Witty mw132 at mole.bio.cam.ac.uk Thu Jul 19 06:38:29 EST 2001 *Previous message: ... So if you are flushing azide down a sink with metal plumbing, over a , ,, period of time a nasty explosive will build up in the ... see: , , http://pubs.acs.org/cen/safety/ , , and a report of a large drum of azide waste exploding: , , http://enquirer.com/ ...
more infohttp://www.bio.net/bionet/mm/methods/2001-July/089719.html

Azide - definition of azide by The Free DictionaryAzide - definition of azide by The Free Dictionary

azide synonyms, azide pronunciation, azide translation, English dictionary definition of azide. n. Chemistry The univalent ... Related to azide: azine, alkyne, Lead azide, Sodium azide az·ide. (ăz′īd, ā′zīd). n. Chemistry The univalent linear group N3, ... az•ide. (ˈæz aɪd, -ɪd, ˈeɪ zaɪd, ˈeɪ zɪd) n. any compound containing the univalent group NH3, as sodium azide. ... Energetic binders that appear to offer such promising characteristics include azide functional polymers like glycidyl azide ...
more infohttp://www.thefreedictionary.com/azide

NIOSHTIC-2  Publications Search - 00177552 - Information Profile. Sodium Azide.NIOSHTIC-2 Publications Search - 00177552 - Information Profile. Sodium Azide.

Sodium-azide (26628228) (NA) was described in terms of general properties and uses, toxicity, and occupational exposures. NA ... Some inorganic azides and HA were highly explosive. HA and NA were found to be strong hypotensive agents which dilate blood ... Sodium-azide (26628228) (NA) was described in terms of general properties and uses, toxicity, and occupational exposures. NA ... Azide stimulated cardiac muscle and dilated coronary vessels directly, and stimulated the central nervous system, causing ...
more infohttps://www.cdc.gov/niosh/nioshtic-2/00177552.html

CDC - NIOSH Pocket Guide to Chemical Hazards -
Sodium azideCDC - NIOSH Pocket Guide to Chemical Hazards - Sodium azide

... or solder in plumbing systems to form an accumulation of the HIGHLY EXPLOSIVE compounds of lead azide & copper azide.] ... Acids, metals, water [Note: Over a period of time, sodium azide may react with copper, lead, brass, ...
more infohttp://www.cdc.gov/niosh/npg/npgd0560.html

Azides | definition of Azides by Medical dictionaryAzides | definition of Azides by Medical dictionary

Azides explanation free. What is Azides? Meaning of Azides medical term. What does Azides mean? ... Looking for online definition of Azides in the Medical Dictionary? ... azide. (redirected from Azides). Also found in: Dictionary, Thesaurus, Encyclopedia. az·ide. (azīd), A compound that contains ... Sodium azide (car air bags), zidovudine.. azide. inhibitor of cytochrome c oxidase (or complex IV) of the respiratory electron- ...
more infohttp://medical-dictionary.thefreedictionary.com/Azides

Barium azide - Substance Information - ECHABarium azide - Substance Information - ECHA

This is unique source of information on the chemicals manufactured and imported in Europe. It covers their hazardous properties, classification and labelling, and information on how to use them safely.. REACH. ...
more infohttps://echa.europa.eu/substance-information/-/substanceinfo/100.038.706

Hydrogen azide - Substance Information - ECHAHydrogen azide - Substance Information - ECHA

This is unique source of information on the chemicals manufactured and imported in Europe. It covers their hazardous properties, classification and labelling, and information on how to use them safely.. REACH. ...
more infohttps://echa.europa.eu/substance-information/-/substanceinfo/100.029.059

sodium azide data sheetsodium azide data sheet

... , from the Compendium of Pesticide Common Names, including IUPAC and CAS systematic names, molecular ...
more infohttp://www.alanwood.net/pesticides/sodium%20azide.html

Sodium azide | NaN3 - PubChemSodium azide | NaN3 - PubChem

Sodium azide , NaN3 or N3Na , CID 33557 - structure, chemical names, physical and chemical properties, classification, patents ...
more infohttps://pubchem.ncbi.nlm.nih.gov/compound/sodium_azide

Sodium-azide dictionary definition | sodium-azide definedSodium-azide dictionary definition | sodium-azide defined

... plural sodium azides) 1. (chemistry) a white, crystalline salt, NaN3; it is explosive, and is used in automobile airbags... ... plural sodium azides) 1. (chemistry) a white, crystalline salt, NaN3; it is explosive, and is used in automobile airbags... ... sodium-azide. Noun (plural sodium azides). *(chemistry) a white, crystalline salt, NaN3; it is explosive, and is used in ... "sodium-azide." YourDictionary, n.d. Web. 11 November 2018. ,https://www.yourdictionary.com/sodium-azide,. ...
more infohttp://www.yourdictionary.com/sodium-azide

Copper-catalysed ligation of azides and acetylenes - The Scripps Research InstituteCopper-catalysed ligation of azides and acetylenes - The Scripps Research Institute

In many instances, the reaction sequence regiospecifically ligates azides and t ... A metal catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to give triazoles. ... At 100 mM azide and 200 mM acetylene, the reaction is complete in 12-14 hours. At 2 mM azide and 4 mM acetylene, the reaction ... Then, the product of the first step is ligated with an azide containing molecule by addition of the azide containing molecule ...
more infohttp://www.freepatentsonline.com/7375234.html

Sodium Azide, 99%, Alfa AesarSodium Azide, 99%, Alfa Aesar

sodium azide, azide, sodium, natriumazid, nemazyd, smite, kazoe, azoture de sodium, sodium azide na n3, hydrazoic acid, sodium ... sodium azide, azide, sodium, natriumazid, nemazyd, smite, kazoe, azoture de sodium, sodium azide na n3, hydrazoic acid, sodium ...
more infohttps://www.fishersci.ca/shop/products/sodium-azide-99-alfa-aesar/AA1431422

The chemistry of vinyl azides - The Azido Group (1971) - Smolinsky - Wiley Online LibraryThe chemistry of vinyl azides - The Azido Group (1971) - Smolinsky - Wiley Online Library

Smolinsky, G. and Pryde, G. A. (1971) The chemistry of vinyl azides, in The Azido Group (1971) (ed S. Patai), John Wiley & Sons ...
more infohttp://onlinelibrary.wiley.com/doi/10.1002/9780470771266.ch10/summary

Sulfo-Cyanine3 azide 95% purity (ab146483) |AbcamSulfo-Cyanine3 azide 95% purity (ab146483) |Abcam

Yellow emitting fluorescent dye azide, with ,95% purity. Water soluble compound. Join researchers using our high quality ... Water soluble yellow emitting fluorescent dye azide for click chemistry. Brightness and photostability of fluorophore, together ...
more infohttps://www.abcam.com/sulfo-cyanine3-azide-yellow-emitting-fluorescent-dye-azide-ab146483.html

Your Metal Azide Worries Are Over  |  In the PipelineYour Metal Azide Worries Are Over | In the Pipeline

Personally, my metal azide requirements are minimal, and very easily satisfied. I can get ... You may not have felt the need for a better synthesis of metal azides. ... This is an interesting one, I wont say near or dear to my heart, but having used silver azide as a prep for lead azide, silver ... You may not have felt the need for a better synthesis of metal azides. Personally, my metal azide requirements are minimal, and ...
more infohttps://blogs.sciencemag.org/pipeline/archives/2014/06/16/your_metal_azide_worries_are_over

Azide - WikipediaAzide - Wikipedia

Heavy metal azides, such as lead azide are primary high explosives detonable when heated or shaken. Heavy-metal azides are ... Aryl azides may be prepared by displacement of the appropriate diazonium salt with sodium azide, or trimethylsilyl azide; ... Some azides are valuable as bioorthogonal chemical reporters. Azides are explosophores and toxins. Sodium azide is toxic (LD50 ... The principal source of the azide moiety is sodium azide. As a pseudohalogen compound, sodium azide generally displaces an ...
more infohttps://en.wikipedia.org/wiki/Azide
  • Signs and symptoms of sodium azide poisoning include lethargy or coma (possibly sudden collapse), dyspnea, tachypnea, tachycardia, and hypotension. (cdc.gov)
  • Steric Effects on the Regioselectivity of an Azide-Alkyne Dipolar Cycloaddition Reaction: The Synthesis of Human Leukocyte Elastase Inhibitors", J. Org. (freepatentsonline.com)
  • 1. A Cu(I) catalyzed process for preparing a 1,4-disubstituted 1,2,3-triazole comprising: contacting an organic azide and a terminal alkyne with a catalytic quantity of Cu(I) ion for a time sufficient to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole. (freepatentsonline.com)
  • Biotin picolyl azide reacts with alkyne to form 1,2,3-triazole by 1,3-dipolar Huisgen cycloaddition through the use of a much lower copper (I) concentration without sacrificing reaction efficiency. (biotium.com)
  • CF® dye azide reacts with alkyne to form 1,2,3-triazole by copper(I) catalyzed 1,3-dipolar Huisgen cycloaddition. (biotium.com)
  • This reaction allows azides to serve as protected -NH2 synthons, as illustrated by the synthesis of 1,1,1-tris(aminomethyl)ethane: 3 H2 + CH3C(CH2N3)3 → CH3C(CH2NH2)3 + 3 N2 In the azide alkyne Huisgen cycloaddition, organic azides react as 1,3-dipoles, reacting with alkynes to give substituted 1,2,3-triazoles. (wikipedia.org)
  • You may not have felt the need for a better synthesis of metal azides. (sciencemag.org)
  • They react with amines to give the corresponding azides: RNH2 → RN3 A classic method for the synthesis of azides is the Dutt-Wormall reaction in which a diazonium salt reacts with a sulfonamide first to a diazoaminosulfinate and then on hydrolysis the azide and a sulfinic acid. (wikipedia.org)
  • Some of copper azide complexes do sound interesting and I would like to try some of these if I can find a decent synthesis for them. (sciencemadness.org)
  • I am certain I have seen patents for rimfire primer compositions that deliberately used copper azide so it would seem that under precise conditions for synthesis it is possible to make a form of copper azide that has predictable properties. (sciencemadness.org)
  • In the laboratory, it is used in organic synthesis to introduce the azide functional group by displacement of halides. (wikipedia.org)
  • Azides can be used as precursors of the metal nitrido complexes. (wikipedia.org)
  • I have made the material but it has been 40 years ago and I observed the same low solubility that produces a colloidal precipitate similarly as for lead azide when strong solutions of precursors are reacted. (sciencemadness.org)
  • Zanirato, P. "Reactivity of Aryl and Heteroaryl Azides with Vinylsilane and Alkynylsilane. (freepatentsonline.com)
  • Azide complexes thus is induced to release N2, generating a metal complex in unusual oxidation states (see high-valent iron). (wikipedia.org)
  • so some transition metals azide may form (probably because of the pseudohalegen behaviour) such complexes as hexacyanoferrate/-ite. (sciencemadness.org)
  • a leader in cancer metabolism-based therapeutics, today announced encouraging results of a preclinical toxicity study of azide drug-loaded Emulsiphan nano emulsions conducted with the National Cancer Institute (NCI) under a Collaboration Agreement. (thefreedictionary.com)
  • Sodium-azide (26628228) (NA) was described in terms of general properties and uses, toxicity, and occupational exposures. (cdc.gov)
  • Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation", Proc. (freepatentsonline.com)
  • Azides may be reduced to amines by hydrogenolysis or with a phosphine (e.g., triphenylphosphine) in the Staudinger reaction. (wikipedia.org)
  • An electrical charge triggered by automobile impact causes sodium azide to explode and convert to nitrogen gas inside the airbag. (cdc.gov)
  • In many instances, the reaction sequence regiospecifically ligates azides and terminal acetylenes to give only 1,4-disubstituted [1,2,triazoles. (freepatentsonline.com)
  • A case in which sodium azide in serum is detected, as determined by a commercial laboratory. (cdc.gov)
  • A clinically compatible case in which a high index of suspicion (credible threat or patient history regarding location and time) exists for sodium azide exposure, or an epidemiologic link exists between this case and a laboratory-confirmed case. (cdc.gov)
  • The seriousness of poisoning caused by sodium azide depends on the amount, route, and length of time of exposure, as well as the age and preexisting medical condition of the person exposed. (cdc.gov)
  • Moving to an area with fresh air is a good way to reduce the possibility of death from exposure to sodium azide. (cdc.gov)
  • Sodium azide is a rapidly acting, potentially deadly chemical that exists as an odorless white solid. (cdc.gov)
  • Energetic binders that appear to offer such promising characteristics include azide functional polymers like glycidyl azide polymer (GAP), poly(3, 3-bisazidomethyloxe-tane) (PBAMO), and poly-(3-azidomethyl-3-methyloxetane) (PAMMO), nitrato polyethers like poly-((3-nitrato methyl)-3-methyl oxetane) (PNIMMO), poly-(glycidyl nitrate) (PGLYN)), poly(vinyl nitrate)s, fluoro-polymers, etc. (thefreedictionary.com)
  • Surface modifiers currently offered include titanates, sulfonyl azide , ester-based wetting agents, and proprietary coatings. (thefreedictionary.com)
  • Personally, my metal azide requirements are minimal, and very easily satisfied. (sciencemag.org)
  • This will surely happen to everything in which you heat up samples of metal azides, and believe me, many of these items will be less sturdy than a corundum crucible. (sciencemag.org)
  • And before making the metal azide in the first place, naturally, you need to ask "Do I want to blow myself to pieces? (sciencemag.org)