AxisHypothalamo-Hypophyseal System: A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.Pituitary-Adrenal System: The interactions between the anterior pituitary and adrenal glands, in which corticotropin (ACTH) stimulates the adrenal cortex and adrenal cortical hormones suppress the production of corticotropin by the anterior pituitary.Body Patterning: The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.Hydrocortisone: The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.Corticosterone: An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)Corticotropin-Releasing Hormone: A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Embryo, Nonmammalian: The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Rotation: Motion of an object in which either one or more points on a line are fixed. It is also the motion of a particle about a fixed point. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Pituitary Gland: A small, unpaired gland situated in the SELLA TURCICA. It is connected to the HYPOTHALAMUS by a short stalk which is called the INFUNDIBULUM.Morphogenesis: The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.Gastrula: The developmental stage that follows BLASTULA or BLASTOCYST. It is characterized by the morphogenetic cell movements including invagination, ingression, and involution. Gastrulation begins with the formation of the PRIMITIVE STREAK, and ends with the formation of three GERM LAYERS, the body plan of the mature organism.In Situ Hybridization: A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.Homeodomain Proteins: Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).Xenopus Proteins: Proteins obtained from various species of Xenopus. Included here are proteins from the African clawed frog (XENOPUS LAEVIS). Many of these proteins have been the subject of scientific investigations in the area of MORPHOGENESIS and development.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Organizers, Embryonic: Cells in certain regions of an embryo that self-regulate embryonic development. These organizers have been found in dorsal and ventral poles of GASTRULA embryos, including Spemann organizer in amphibians, and Hensen node in chicken and mouse. These organizer cells communicate with each other via a network of secreted signaling proteins, such as BONE MORPHOGENETIC PROTEINS and their antagonists (chordin and noggin).Hypothalamus: Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.Embryonic Induction: The complex processes of initiating CELL DIFFERENTIATION in the embryo. The precise regulation by cell interactions leads to diversity of cell types and specific pattern of organization (EMBRYOGENESIS).Mesoderm: The middle germ layer of an embryo derived from three paired mesenchymal aggregates along the neural tube.Nodal Protein: The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.Cell Polarity: Orientation of intracellular structures especially with respect to the apical and basolateral domains of the plasma membrane. Polarized cells must direct proteins from the Golgi apparatus to the appropriate domain since tight junctions prevent proteins from diffusing between the two domains.Stress, Psychological: Stress wherein emotional factors predominate.Restraint, Physical: Use of a device for the purpose of controlling movement of all or part of the body. Splinting and casting are FRACTURE FIXATION.Stress, Physiological: The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.Zebrafish Proteins: Proteins obtained from the ZEBRAFISH. Many of the proteins in this species have been the subject of studies involving basic embryological development (EMBRYOLOGY).Pituitary-Adrenal Function Tests: Tests that evaluate the adrenal glands controlled by pituitary hormones.Ectoderm: The outer of the three germ layers of an embryo.Insulin-Like Growth Factor I: A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.Genes, Homeobox: Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.Zebrafish: An exotic species of the family CYPRINIDAE, originally from Asia, that has been introduced in North America. They are used in embryological studies and to study the effects of certain chemicals on development.Time Factors: Elements of limited time intervals, contributing to particular results or situations.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Neurosecretory Systems: A system of NEURONS that has the specialized function to produce and secrete HORMONES, and that constitutes, in whole or in part, an ENDOCRINE SYSTEM or organ.Wnt Proteins: Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Adrenal Glands: A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.Drosophila Proteins: Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Growth Hormone: A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.Extremities: The farthest or outermost projections of the body, such as the HAND and FOOT.Xenopus: An aquatic genus of the family, Pipidae, occurring in Africa and distinguished by having black horny claws on three inner hind toes.Chemokine CXCL12: A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.Paraventricular Hypothalamic Nucleus: Nucleus in the anterior part of the HYPOTHALAMUS.Mice, Inbred C57BLGonadotropin-Releasing Hormone: A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.Luteinizing Hormone: A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Chick Embryo: The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.Drosophila: A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Gastrulation: A process of complicated morphogenetic cell movements that reorganizes a bilayer embryo into one with three GERM LAYERS and specific orientation (dorsal/ventral; anterior/posterior). Gastrulation describes the germ layer development of a non-mammalian BLASTULA or that of a mammalian BLASTOCYST.beta Catenin: A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.Embryonic Development: Morphological and physiological development of EMBRYOS.Goosecoid Protein: Goosecoid protein is a homeodomain protein that was first identified in XENOPUS. It is found in the SPEMANN ORGANIZER of VERTEBRATES and plays an important role in neuronal CELL DIFFERENTIATION and ORGANOGENESIS.Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Receptors, CXCR4: CXCR receptors with specificity for CXCL12 CHEMOKINE. The receptors may play a role in HEMATOPOIESIS regulation and can also function as coreceptors for the HUMAN IMMUNODEFICIENCY VIRUS.Celiac Artery: The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.Reflex, Vestibulo-Ocular: A reflex wherein impulses are conveyed from the cupulas of the SEMICIRCULAR CANALS and from the OTOLITHIC MEMBRANE of the SACCULE AND UTRICLE via the VESTIBULAR NUCLEI of the BRAIN STEM and the median longitudinal fasciculus to the OCULOMOTOR NERVE nuclei. It functions to maintain a stable retinal image during head rotation by generating appropriate compensatory EYE MOVEMENTS.Receptors, Corticotropin-Releasing Hormone: Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Bone Morphogenetic Proteins: Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Endoderm: The inner of the three germ layers of an embryo.Receptors, Glucocorticoid: Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Xenopus laevis: The commonest and widest ranging species of the clawed "frog" (Xenopus) in Africa. This species is used extensively in research. There is now a significant population in California derived from escaped laboratory animals.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Feedback, Physiological: A mechanism of communication with a physiological system for homeostasis, adaptation, etc. Physiological feedback is mediated through extensive feedback mechanisms that use physiological cues as feedback loop signals to control other systems.Saliva: The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.Thyroid Gland: A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.Personality Disorders: A major deviation from normal patterns of behavior.Insulin-Like Growth Factor Binding Protein 3: One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.Biomechanical Phenomena: The properties, processes, and behavior of biological systems under the action of mechanical forces.Somites: Paired, segmented masses of MESENCHYME located on either side of the developing spinal cord (neural tube). Somites derive from PARAXIAL MESODERM and continue to increase in number during ORGANOGENESIS. Somites give rise to SKELETON (sclerotome); MUSCLES (myotome); and DERMIS (dermatome).Testosterone: A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cosyntropin: A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of ADRENOCORTICOTROPIC HORMONE. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of CORTICOSTEROIDS in the ADRENAL CORTEX.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.WingInsect Proteins: Proteins found in any species of insect.Circadian Rhythm: The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs and stimuli, hormone secretion, sleeping, and feeding.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Gonads: The gamete-producing glands, OVARY or TESTIS.Trans-Activators: Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Blastomeres: Undifferentiated cells resulting from cleavage of a fertilized egg (ZYGOTE). Inside the intact ZONA PELLUCIDA, each cleavage yields two blastomeres of about half size of the parent cell. Up to the 8-cell stage, all of the blastomeres are totipotent. The 16-cell MORULA contains outer cells and inner cells.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Dexamethasone: An anti-inflammatory 9-fluoro-glucocorticoid.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Orientation: Awareness of oneself in relation to time, place and person.Borderline Personality Disorder: A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Thyrotropin: A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.Radioimmunoassay: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.Blastoderm: A layer of cells lining the fluid-filled cavity (blastocele) of a BLASTULA, usually developed from a fertilized insect, reptilian, or avian egg.Nervous System: The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Pro-Opiomelanocortin: A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).Human Growth Hormone: A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.Transcription Factor 3: A basic helix-loop-helix transcription factor that plays a role in determining cell fate during embryogenesis. It forms a heterodimer with TWIST TRANSCRIPTION FACTOR and ACHAETE-SCUTE GENE COMPLEX-related TRANSCRIPTION FACTORS.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Thyrotropin-Releasing Hormone: A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.Semicircular Canals: Three long canals (anterior, posterior, and lateral) of the bony labyrinth. They are set at right angles to each other and are situated posterosuperior to the vestibule of the bony labyrinth (VESTIBULAR LABYRINTH). The semicircular canals have five openings into the vestibule with one shared by the anterior and the posterior canals. Within the canals are the SEMICIRCULAR DUCTS.Cell Line, Tumor: A cell line derived from cultured tumor cells.Head Movements: Voluntary or involuntary motion of head that may be relative to or independent of body; includes animals and humans.Kisspeptins: Intercellular signaling peptides that were originally characterized by their ability to suppress NEOPLASM METASTASIS. Kisspeptins have since been found to play an important role in the neuroendocrine regulation of REPRODUCTION.Organ Size: The measurement of an organ in volume, mass, or heaviness.Sea Urchins: Somewhat flattened, globular echinoderms, having thin, brittle shells of calcareous plates. They are useful models for studying FERTILIZATION and EMBRYO DEVELOPMENT.Follicle Stimulating Hormone: A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.Hedgehog Proteins: A family of intercellular signaling proteins that play and important role in regulating the development of many TISSUES and organs. Their name derives from the observation of a hedgehog-like appearance in DROSOPHILA embryos with genetic mutations that block their action.Cytoskeletal Proteins: Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.DNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Limb Buds: Distinct regions of mesenchymal outgrowth at both flanks of an embryo during the SOMITE period. Limb buds, covered by ECTODERM, give rise to forelimb, hindlimb, and eventual functional limb structures. Limb bud cultures are used to study CELL DIFFERENTIATION; ORGANOGENESIS; and MORPHOGENESIS.Zygote: The fertilized OVUM resulting from the fusion of a male and a female gamete.Endocrine System: The system of glands that release their secretions (hormones) directly into the circulatory system. In addition to the ENDOCRINE GLANDS, included are the CHROMAFFIN SYSTEM and the NEUROSECRETORY SYSTEMS.Gravitation: Acceleration produced by the mutual attraction of two masses, and of magnitude inversely proportional to the square of the distance between the two centers of mass. It is also the force imparted by the earth, moon, or a planet to an object near its surface. (From NASA Thesaurus, 1988)Sexual Maturation: Achievement of full sexual capacity in animals and in humans.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Insulin-Like Growth Factor Binding Proteins: A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. (Int J Gynaecol Obstet 1992;39(1):3-9)Microscopy, Electron: Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.Pituitary Hormones: Hormones secreted by the PITUITARY GLAND including those from the anterior lobe (adenohypophysis), the posterior lobe (neurohypophysis), and the ill-defined intermediate lobe. Structurally, they include small peptides, proteins, and glycoproteins. They are under the regulation of neural signals (NEUROTRANSMITTERS) or neuroendocrine signals (HYPOTHALAMIC HORMONES) from the hypothalamus as well as feedback from their targets such as ADRENAL CORTEX HORMONES; ANDROGENS; ESTROGENS.Animals, Genetically Modified: ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.Cervical Atlas: The first cervical vertebra.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Imaging, Three-Dimensional: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.Thyroid Hormones: Natural hormones secreted by the THYROID GLAND, such as THYROXINE, and their synthetic analogs.Receptors, G-Protein-Coupled: The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.Testis: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.Adrenal Insufficiency: Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Drosophila melanogaster: A species of fruit fly much used in genetics because of the large size of its chromosomes.TailOogenesis: The process of germ cell development in the female from the primordial germ cells through OOGONIA to the mature haploid ova (OVUM).Hypothalamic Diseases: Neoplastic, inflammatory, infectious, and other diseases of the hypothalamus. Clinical manifestations include appetite disorders; AUTONOMIC NERVOUS SYSTEM DISEASES; SLEEP DISORDERS; behavioral symptoms related to dysfunction of the LIMBIC SYSTEM; and neuroendocrine disorders.Microtubules: Slender, cylindrical filaments found in the cytoskeleton of plant and animal cells. They are composed of the protein TUBULIN and are influenced by TUBULIN MODULATORS.Sex Characteristics: Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.Genes, Insect: The functional hereditary units of INSECTS.T-Box Domain Proteins: Proteins containing a region of conserved sequence, about 200 amino acids long, which encodes a particular sequence specific DNA binding domain (the T-box domain). These proteins are transcription factors that control developmental pathways. The prototype of this family is the mouse Brachyury (or T) gene product.Bone Malalignment: Displacement of bones out of line in relation to joints. It may be congenital or traumatic in origin.Fetal Proteins: Proteins that are preferentially expressed or upregulated during FETAL DEVELOPMENT.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Arginine Vasopressin: The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.Transforming Growth Factor beta: A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.Diagnostic and Statistical Manual of Mental Disorders: Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)Repressor Proteins: Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.Ovary: The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Fibroblast Growth Factors: A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.Receptors, Mineralocorticoid: Cytoplasmic proteins that specifically bind MINERALOCORTICOIDS and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA.Models, Anatomic: Three-dimensional representation to show anatomic structures. Models may be used in place of intact animals or organisms for teaching, practice, and study.Central Nervous System: The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Hormones: Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.Pituitary Gland, Anterior: The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the ADENOHYPOPHYSEAL HORMONES that regulate vital functions such as GROWTH; METABOLISM; and REPRODUCTION.RNA Interference: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.X-Ray Diffraction: The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Eye Movements: Voluntary or reflex-controlled movements of the eye.Leptin: A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Proto-Oncogene Proteins: Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.Movement: The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.Microinjections: The injection of very small amounts of fluid, often with the aid of a microscope and microsyringes.Somatomedins: Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.Acceleration: An increase in the rate of speed.Heterocyclic Compounds: Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)Animals, Newborn: Refers to animals in the period of time just after birth.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.HMGB Proteins: A family of sequence-related proteins similar to HMGB1 PROTEIN that contains specific HMG-BOX DOMAINS.Intercellular Signaling Peptides and Proteins: Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.Vertebrates: Animals having a vertebral column, members of the phylum Chordata, subphylum Craniata comprising mammals, birds, reptiles, amphibians, and fishes.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Gravity Sensing: Process whereby a cell, bodily structure, or organism (animal or plant) receives or detects a gravity stimulus. Gravity sensing plays an important role in the directional growth and development of an organism (GRAVITROPISM).Adrenalectomy: Excision of one or both adrenal glands. (From Dorland, 28th ed)Larva: Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Rhombencephalon: The posterior of the three primitive cerebral vesicles of an embryonic brain. It consists of myelencephalon, metencephalon, and isthmus rhombencephali from which develop the major BRAIN STEM components, such as MEDULLA OBLONGATA from the myelencephalon, CEREBELLUM and PONS from the metencephalon, with the expanded cavity forming the FOURTH VENTRICLE.Bone Morphogenetic Protein 4: A bone morphogenetic protein that is a potent inducer of bone formation. It also functions as a regulator of MESODERM formation during EMBRYONIC DEVELOPMENT.Birefringence: The property of nonisotropic media, such as crystals, whereby a single incident beam of light traverses the medium as two beams, each plane-polarized, the planes being at right angles to each other. (Cline et al., Dictionary of Visual Science, 4th ed)Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Cell Lineage: The developmental history of specific differentiated cell types as traced back to the original STEM CELLS in the embryo.Wnt1 Protein: A proto-oncogene protein and member of the Wnt family of proteins. It is expressed in the caudal MIDBRAIN and is essential for proper development of the entire mid-/hindbrain region.Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.Vestibule, Labyrinth: An oval, bony chamber of the inner ear, part of the bony labyrinth. It is continuous with bony COCHLEA anteriorly, and SEMICIRCULAR CANALS posteriorly. The vestibule contains two communicating sacs (utricle and saccule) of the balancing apparatus. The oval window on its lateral wall is occupied by the base of the STAPES of the MIDDLE EAR.Prolactin: A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Mice, Mutant Strains: Mice bearing mutant genes which are phenotypically expressed in the animals.Median Eminence: Raised area at the infundibular region of the HYPOTHALAMUS at the floor of the BRAIN, ventral to the THIRD VENTRICLE and adjacent to the ARCUATE NUCLEUS OF HYPOTHALAMUS. It contains the terminals of hypothalamic neurons and the capillary network of hypophyseal portal system, thus serving as a neuroendocrine link between the brain and the PITUITARY GLAND.Interleukin-23: A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa subunit that is shared with INTERLEUKIN-12. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. (1/149)

Specification of the left-right (L-R) axis in the vertebrate embryo requires transfer of positional information from the node to the periphery, resulting in asymmetric gene expression in the lateral plate mesoderm. We show that this activation of L-R lateral asymmetry requires the evolutionarily conserved activity of members of the EGF-CFC family of extracellular factors. Targeted disruption of murine Cryptic results in L-R laterality defects including randomization of abdominal situs, hyposplenia, and pulmonary right isomerism, as well as randomized embryo turning and cardiac looping. Similarly, zebrafish one-eyed pinhead (oep) mutants that have been rescued partially by mRNA injection display heterotaxia, including randomization of heart looping and pancreas location. In both Cryptic and oep mutant embryos, L-R asymmetric expression of Nodal/cyclops, Lefty2/antivin, and Pitx2 does not occur in the lateral plate mesoderm, while in Cryptic mutants Lefty1 expression is absent from the prospective floor plate. Notably, L-R asymmetric expression of Nodal at the lateral edges of the node is still observed in Cryptic mutants, indicating that L-R specification has occurred in the node but not the lateral plate. Combined with the previous finding that oep is required for nodal signaling in zebrafish, we propose that a signaling pathway mediated by Nodal and EGF-CFC activities is essential for transfer of L-R positional information from the node.  (+info)

Pattern formation and regulation of gene expressions in chick recombinant limbs. (2/149)

Recombinant limbs were performed by ensembling dissociated-reaggregated wing bud mesoderm inside an ectodermal hull. The zone of polarizing activity was excluded from the mesoderm used to perform the recombinant limbs (non-polarized recombinants), and grafted when desired (polarized recombinants). Reorganization of patterning progressively occurred in the newly formed progress zone under the influence of the apical ectodermal ridge (AER), explaining the proximo-distal gradient of morphogenesis observed in developed recombinant limbs. The AER, without the influence of the polarizing region (ZPA), was sufficient to direct outgrowth and appropriate proximo-distal patterning, as observed in the expression of the Hoxa-11 and Hoxa-13 genes. The development of the recombinant limbs coursed with symmetric AER and downregulation of Bmp expression in the mesoderm supporting a negative effect of Bmp signaling upon the apical ridge. The recombinant ectoderm maintained previously established compartments of gene expressions and organized a correct dorso-ventral patterning in the recombinant progress zone. Finally, the ZPA effect was only detected on Bmp expression and pattern formation along the antero-posterior axis.  (+info)

Left-right development: the roles of nodal cilia. (3/149)

Cilia on the ventral side of the mouse node have been implicated in initiating the left-right axis during embryonic development, but how cilia relate to other factors in the left-right pathway and the mechanism by which cilia convey patterning information remain uncertain.  (+info)

Surface ectoderm is necessary for the morphogenesis of somites. (4/149)

The paraxial mesoderm of the neck and trunk of mouse embryos undergoes extensive morphogenesis in forming somites. Paraxial mesoderm is divided into segments, it elongates along its anterior posterior axis, and its cells organize into epithelia. Experiments were performed to determine if these processes are autonomous to the mesoderm that gives rise to the somites. Presomitic mesoderm at the tailbud stage was cultured in the presence and absence of its adjacent tissues. Somite segmentation occurred in the absence of neural tube, notochord, gut and surface ectoderm, and occurred in posterior fragments in the absence of anterior presomitic mesoderm. Mesodermal expression of Dll1 and Notch1, genes with roles in segmentation, was largely independent of other tissues, consistent with autonomous segmentation. However, surface ectoderm was found to be necessary for elongation of the mesoderm along the anterior-posterior axis and for somite epithelialization. To determine if there is specificity in the interaction between ectoderm and mesoderm, ectoderm from different sources was recombined with presomitic mesoderm. Surface ectoderm from only certain parts of the embryo supported somite epithelialization and elongation. Somite epithelialization induced by ectoderm was correlated with expression of the basic-helix-loop-helix gene Paraxis in the mesoderm. This is consistent with the genetically defined requirement for Paraxis in somite epithelialization. However, trunk ectoderm was able to induce somite epithelialization in the absence of strong Paraxis expression. We conclude that somitogenesis consists of autonomous segmentation patterned by Notch signaling and nonautonomous induction of elongation and epithelialization by surface ectoderm.  (+info)

Regulatory gene expression patterns reveal transverse and longitudinal subdivisions of the embryonic zebrafish forebrain. (5/149)

To shed light on the organization of the rostral embryonic brain of a lower vertebrate, we have directly compared the expression patterns of dlx, fgf, hh, hlx, otx, pax, POU, winged helix and wnt gene family members in the fore- and midbrain of the zebrafish. We show that the analyzed genes are expressed in distinct transverse and longitudinal domains and share expression boundaries at stereotypic positions within the fore- and midbrain. Some of these shared expression boundaries coincide with morphological landmarks like the pathways of primary axon tracts. We identified a series of eight transverse diencephalic domains suggestive of neuromeric subdivisions within the rostral brain. In addition, we identified four molecularly distinct longitudinal subdivisions and provide evidence for a strong bending of the longitudinal rostral brain axis at the cephalic flexure. Our data suggest a strong conservation of early forebrain organization between lower and higher vertebrates.  (+info)

BMP-4 affects the differentiation of metanephric mesenchyme and reveals an early anterior-posterior axis of the embryonic kidney. (6/149)

Bone morphogenetic protein-4 (BMP4), a member of the transforming growth factor-beta (TGF-beta) family, regulates several developmental processes during animal development. We have now studied the effects of BMP-4 in the metanephric kidney differentiation by using organ culture technique. Human recombinant BMP-4 diminishes the number of ureteric branches and changes the branching pattern. Our data suggest that BMP-4 affects the ureteric branching indirectly via interfering with the differentiation of the nephrogenic mesenchyme. The clear positional preference of the defects to posterior mesenchyme might reflect an early anterior-posterior patterning of the metanephric mesenchyme. The smooth muscle alpha-actin expressing cell population around the ureteric stalk, highly expressing Bmp-4 mRNA, is also expanded in kidneys treated with BMP-4. Thus, BMP-4 may be a physiological regulator of the development of the periureteric smooth muscle layer and ureteric elongation.  (+info)

Anteroposterior patterning is required within segments for somite boundary formation in developing zebrafish. (7/149)

Somite formation involves the establishment of a segmental prepattern in the presomitic mesoderm, anteroposterior patterning of each segmental primordium and formation of boundaries between adjacent segments. How these events are co-ordinated remains uncertain. In this study, analysis of expression of zebrafish mesp-a reveals that each segment acquires anteroposterior regionalisation when located in the anterior presomitic mesoderm. Thus anteroposterior patterning is occurring after the establishment of a segmental prepattern in the paraxial mesoderm and prior to somite boundary formation. Zebrafish fss(-), bea(-), des(-) and aei(-) embryos all fail to form somites, yet we demonstrate that a segmental prepattern is established in the presomitic mesoderm of all these mutants and hox gene expression shows that overall anteroposterior patterning of the mesoderm is also normal. However, analysis of various molecular markers reveals that anteroposterior regionalisation within each segment is disturbed in the mutants. In fss(-), there is a loss of anterior segment markers, such that all segments appear posteriorized, whereas in bea(-), des(-) and aei(-), anterior and posterior markers are expressed throughout each segment. Since somite formation is disrupted in these mutants, correct anteroposterior patterning within segments may be a prerequisite for somite boundary formation. In support of this hypothesis, we show that it is possible to rescue boundary formation in fss(-) through the ectopic expression of EphA4, an anterior segment marker, in the paraxial mesoderm. These observations indicate that a key consequence of the anteroposterior regionalisation of segments may be the induction of Eph and ephrin expression at segment interfaces and that Eph/ephrin signalling subsequently contributes to the formation of somite boundaries.  (+info)

Dorsoventral axis determination in the somite: a re-examination. (8/149)

We have repeated classic dorsoventral somite rotation experiments (Aoyama and Asamoto, 1988, Development 104, 15-28) and included dorsal and ventral gene expression markers for the somitogenic tissue types, myotome and sclerotome, respectively. While the histological results are consistent with those previously published, gene expression analysis indicates that cells previously thought to be 'sclerotome' no longer express Pax1 mRNA, a sclerotome marker. These results, together with recent quail-chick transplantation experiments indicating that even very late sclerotome tissue fragments are multipotential (Dockter and Ordahl, 1998, Development 125, 2113-2124), lead to the conclusion that sclerotome tissue remains phenotypically and morphogenetically plastic during early embryonic somitogenesis. Myotome precursor cells, by contrast, appear to be determined within hours after somite epithelization; a finding consistent with recent reports (Williams and Ordahl, 1997, Development 124, 4983-4997). Therefore, while these findings support a central conclusion of Aoyama and Asamoto, that axis determination begins to occur within hours after somite epithelialization, the identity of the responding tissues, myotome versus sclerotome, differs. A simple model proposed to reconcile these observations supports the general hypothesis that determinative aspects of early paraxial mesoderm growth and morphogenesis occur in early and late phases that are governed principally by the myotome and sclerotome, respectively.  (+info)

*Yahoo! Axis

On June 28, 2013, Yahoo announced the discontinuation of the Axis. Axis replaces the standard search results page in other ... Rafe Needleman (23 May 2012). "Here comes Yahoo's own Web browser -- Axis". CNET. Retrieved 23 May 2012. "What is Yahoo Axis ... Yahoo Axis was a desktop web browser extension and mobile browser for iOS devices created and developed by Yahoo. The browser ... Chirgwin, Richard (24 May 2012). "Yahoo leaks! private! key! in! Axis! Chrome! debut!". The Register. Retrieved 25 May 2012. ...

*Black Axis

"Black Axis". Allmusic. Retrieved March 28, 2013. Sprague, David (2007). "Caspar Brötzmann Massaker". Trouser Press. Retrieved ... Black Axis at Discogs (list of releases). ...

*Monumental Axis

The Monumental Axis ("Eixo Monumental" in Portuguese) is a central avenue in Brasília's city design. The avenue begins on the ... A common urban legend persists that the Monumental Axis is the widest road in the world, where "[100 to 160] cars can drive ... Coordinates: 15°47′13″S 47°54′13″W / 15.78694°S 47.90361°W / -15.78694; -47.90361 (Monumental Axis). ... Many important government buildings, monuments and memorials are located on the Monumental Axis. ...

*Axis Communications

"AXIS T8646 PoE+ over Coax Blade from Axis Communications." Apr 22, 2014. Dec 10, 2014. Tom Coyne, Security News Desk. "Axis ... "Axis to sell Canon solutions in EMEA." September 1, 2016. Retrieved December 21, 2016. Tim Scally, SDM Magazine. "Axis to Take ... In 1996, Axis Communications introduced the industry's first network camera, the AXIS 200. This was followed in 1999 by the ... Axis Communications sells a video management software which it markets under the name AXIS Camera Station. The software ...

*Axis Mutatis

... is an album by electronic music group The Shamen which was released in 1995. The album didn't receive as much ... The initial release of Axis Mutatis contained an additional instrumental album, Arbor Bona Arbor Mala. "Destination Eschaton ... "Axis Mundi" - 7:04 a. "Tellos" b. "Xibalba" c. "Nemeton" d. "Eternal Return" "Eschaton Omega (Deep Melodic Techno Mix)" - 3:37 ... "Agua Azul - 11:23 "S2 Translation" - 3:31 Asymptotic Eschaton - 0:48 Sefirotic Axis - 6:52 Entraterrestrial - 9:38 Demeter - 4: ...

*Amyna axis

The Eight-Spot (Amyna axis) is a moth of the Erebidae family. It is found in the tropics and subtropics worldwide, and occurs ... "Amyna axis, Guenée, 1852". African Moths. Retrieved 3 August 2016. Hampson G. F. (1892). "The Fauna Of British India Including ... Wagner, DL; Binns S (2010). Larva and pupa of Amyna axis (Guenée, 1852) and affirmation of its taxonomic placement in ...

*Axis (anatomy)

In anatomy, the second cervical vertebra (C2) of the spine is named the axis (from Latin axis, "axle") or epistropheus. By the ... Axis seen from above. Posterior atlantooccipital membrane and atlantoaxial ligament. (Axis visible at center.) Median sagittal ... Axis on x-ray Unfused arch of atlas at CT. This article incorporates text in the public domain from the 20th edition of Gray's ... The odontoid peg is the ascension of the atlas fused to the ascension of the axis. The peg has an articular facet at its front ...

*Daphnella axis

... is a species of sea snail, a marine gastropod mollusk in the family Raphitomidae. Daphnella axis (Reeve, 1846). ...

*Axis Of

http://www.smalltownamerica.co.uk/artists/axis-of Axis Of on Myspace Axis Of on Facebook Axis Of at BBC Music. ... Axis Of are a three-piece alternative rock band from Portstewart, Northern Ireland. The band is composed of Niall Lawlor ( ... Axis Of have supported Therapy?, The King Blues, Deaf Havana, Twin Atlantic, The Joy Formidable, Lower Than Atlantis, The Bronx ... "Port Na Spaniagh" music video "Axis Of at Maida Vale Studios". BBC Online. 13 January 2011. Retrieved 29 August 2012. Missing ...

*Luminous Axis

... at Tzadik arwulf, arwulf. Wadada Leo Smith - Luminous Axis: Review at AllMusic. Retrieved April 1, 2017. Cook, ... Luminous Axis (subtitled The Caravans of Winter and Summer) is an album by American jazz trumpeter Wadada Leo Smith which was ... "Luminous Axis should draw emphatic interest from listeners curious about the exploration of modern compositional style and ... Luminous Axis review at All About Jazz. ...

*Axis Percussion

Some Axis pedals, called longboards, are unusual in having straight flat foot plates with no heel plates. Users of Axis ... Axis Percussion is a United States company specializing in the manufacture of precision drum pedals and drum hardware. The ... Axis percussion website World's fastest drummer website. ...

*Axis Sally

... was the generic nickname given to women radio personalities who broadcast English-language propaganda on behalf of ... Lucas, Richard (2010). Axis Sally : the American voice of Nazi Germany. Philadelphia, Pa.: Casemate. ISBN 9781935149804. OCLC ... http://www.historynet.com/axis-sally.htm http://www.findingdulcinea.com/news/on-this-day/March-April-08/On-this-day---Axis- ... Wireless (8 June 1945). "Americans Seize Axis Sally in Italy". New York Times. p. 9. Retrieved 10 October 2017. ...

*Axis mundi

The axis mundi (also cosmic axis, world axis, world pillar, center of the world, world tree), in certain beliefs and ... Plants often serve as images of the axis mundi. The image of the Cosmic Tree provides an axis symbol that unites three planes: ... This artistic representation of axis mundi opens the mind up to a new visual dimension both energistic and shamanic. Axis mundi ... Because the axis mundi is an idea that unites a number of concrete images, no contradiction exists in regarding multiple spots ...

*Axis Amerika

... they have no relation to the original Axis Amerika. Axis America was a secret fascist cult who ran a children's home called ... The Axis suffer a major defeat but return. The All-Stars are aided in this second fight by a similar group of heroes known as ... Axis Amerika is the name of two different teams of super-villains who have appeared in DC Comics. The team, created by writer ... The new Axis America consists of Übermensch (Shepherd), Hel (Vela), Zaladin, Fleshburn and Great White. Great White - Fleshburn ...

*Petrophila axis

... is a moth in the Crambidae family. It was described by Hampson in 1895. It is found in Grenada. "global ...

*Pseudoclanis axis

... is a moth of the family Sphingidae. It is known from Cameroon. "CATE Creating a Taxonomic eScience - ...

*Axis (novel)

"Axis." Kirkus Reviews 75.13 (July 2007): 8-8. Cassada, Jackie. "Axis." Library Journal 132.15 (15 Sep. 2007): 54-55. Axis title ... "Axis." Publishers Weekly 254.31 (06 Aug. 2007): 173-173. Schroeder, Regina. "Axis." Booklist 104.1 (Sep. 2007): 65. " ... Axis takes place on the new planet introduced at the end of Spin, a world the Hypotheticals engineered to support human life ... Axis is a science fiction novel by author Robert Charles Wilson, published in 2007. It is a direct sequel to Wilson's Hugo ...

*Apache Axis

... axis.apache.org/axis/java/user-guide.html#Publishing_Web_Services_with_Axis . It will expose methods add and subtract of class ... Axis development takes place under the auspices of the Apache Software Foundation. When using the Java version of Axis there ... An example for implementing and deploying a simple web-service with the C++ version of Axis can be found in the Axis-CPP ... Axis2 Apache Axis Homepage at the Apache Software Foundation Apache Axis C++ Homepage at the Apache Software Foundation Axis- ...

*Axis (song)

"Axis" is the first track from the Pet Shop Boys album Electric, released as a promotional single on 30 April 2013. "Axis" was ... On April 30, 2013, a music for "Axis" was released. Haider, Arwa (5 July 2013). "Pet Shop Boys: We left major label Parlophone ... Hogan, Marc (30 April 2013). "Pet Shop Boys Preview 'Pretty Banging' LP 'Electric' With Rave-y 'Axis' Video". SPIN Magazine. ... http://www.discogs.com/Pet-Shop-Boys-Axis/release/4731543 "Pet Shop Boys - News - Axis 12" single". Petshopboys.co.uk. ...

*Super-Axis

The Super-Axis, consisting of former Invaders foes Master Man; U-Man; the original Baron Blood and Warrior Woman are gathered ... The Super-Axis is a group of fictional characters and supervillains appearing in American comic books published by Marvel ... In a final battle at an amusement park, the entire Super-Axis confront the Invaders, but are defeated by the heroes' superior ... Using hypnotism to summon and control the villains, Lotus intends to use the newly formed Super-Axis to undermine the United ...

*Discordance Axis

Hydra Head Records Official website Discordance Axis at AllMusic Discordance Axis at MySpace Interview with Dave Witte at ... Discordance Axis was a grindcore band from East Brunswick, New Jersey. Frontman Jon Chang on the history of the band: " ... Discordance Axis started in 1992 and broke up in 2001. All of our music has been re-issued on CD except for our tracks on the ... "Discordance Axis was a three piece grind core band that started in NJ around 1992. The band started after myself and Rob's ...

*Axis, Alabama

Axis is an unincorporated community and census-designated place in Mobile County, Alabama, United States. It has a post office ... Axis is located at 30°55′48″N 88°01′38″W / 30.92990°N 88.02722°W / 30.92990; -88.02722Coordinates: 30°55′48″N 88°01′38″W ... Prior to the split of Satsuma from the Mobile County system, Axis was zoned to Satsuma High School. In 2011 Renee Busbee of the ... As of the 2010 census, Axis had a population of 757. The racial and ethnic makeup of the population was 66.8% white, 26.9% ...

*Expo Axis

... , May 2010 Expo Axis, May 2010 Expo Axis, May 2010 Sun Valley Expo Axis, May 2010 Membrane Construction Expo Axis, May ... The Expo Axis and its boulevard is one of five buildings which remain after the end of the world expo to form the centre of a ... The Expo Axis is covered by a membrane roof with a total surface of 65,000 m2, currently the largest of its kind in the world. ... The Expo Axis is one of the world's largest membrane roofs. It spanned the entrance and boulevard building of the World ...

*Axis powers

The Axis powers agreed on their opposition to the Allies, but did not completely coordinate their activity. The Axis grew out ... Unlike other Axis powers, Yugoslavia was not obliged to provide military assistance, nor to provide its territory for Axis to ... The Axis championed a number of variants on fascism, militarism, and autarky. The Axis population in 1938 was 258.9 million, ... The Axis powers (German: Achsenmächte, Italian: Potenze dell'Asse, Japanese: 枢軸国 Sūjikukoku), also known as the Axis and the ...

*Voeykov axis

... (or Voeikov axis) is the axial portion (ridge) of a high atmospheric pressure band stretching across Eurasia ... Winter in Eurasia the Voeнkov axis plays an important climate role as a major winds separator. In winter, the north of the axis ... West departs Voeykov axis, which can be traced on the territory of Kazakhstan and in the south of the East European Plain. It ... This Voeнkov axis is stored in a weakened state, but loses its value vetrorazdelnoe.[clarification needed] During this period ...
Under the titel Occipital Neuralgia Responding to Palmitoylethanolamide Rocco Salvatore Calabrò and Placido Bramanti reported a case in Headache, a female patient affected by occiptal-treatment-refractory-neuralgia that greatly improved after oral intake of palmitoylethanolamide (PEA). Occipital neuralgia (ON) is defined as paroxysmal shooting or stabbing pain in the dermatomes of the nervus occipitalis major or nervus…
Neurological symptoms following the use of potent antiplatelet agents and anticoagulants during PCI always raise the frightening possibility of a major intracranial haemorrhage. The purpose of this report is to emphasise that the importance of excluding intracranial haemorrhage as a cause for the neurological symptoms after PCI far exceeds that after angiography, as inappropriate withdrawal or continuation of the antiplatelet agents could both result in serious consequences for the patient. The fact that the appearance of the CT scan raised a suspicion of an intracranial bleed makes the differentiation all the more important as an opinion of a specialist neuroradiologist may not be available out-of-hours. And, radiology is possibly the only investigation available as lumbar puncture for cerebrospinal fluid (CSF) xanthochromia is contraindicated in these patients. The anatomical location of any bleeding is less important.. In the clinical scenario presented, intracranial bleeding needed to be ...
Ring of Honor held TV tapings this weekend in Chicago. Those episodes will probably not begin airing until after the "Best in the World" PPV on June 23rd.. This week, ROH TV was once again from Philadelphia, having been taped the night after the War of the Worlds PPV. The main event for the show was Adam Cole taking on Bullet Clubs Hangman Page. Next week, Kushida defends the TV title against the newest member of Bullet Club, Marty Scurll.. ...
Hopscotch, Hangman, Hot Potato, and Ha, Ha, Ha (Heftet) av forfatter Jack Maguire. Pris kr 159. Se flere bøker fra Jack Maguire.
History: Individuals report pain as well as tingling and numbness (paresthesia) in the neck, shoulder, arm, and hand, or in all four locations. In neurogenic TOS, hand pain can be severe in the fourth and fifth fingers. Individuals may report that the pain is aggravated by use of the arm, and fatigue of the arm is often marked. Pain and paresthesia may be enough to awaken individuals from sleep. Other symptoms may include recurrent headaches, particularly in the back of the head (occipital headaches), and neck pain. Individuals experiencing venous TOS may also report swelling of the arm, a bluish tinge to the skin (cyanosis), and coldness of the affected arm and hand. Arterial TOS often is not detected until migration of a blood clot obstructs an artery (thromboembolic event). Some individuals may report a history of neck trauma preceding symptoms, usually from a motor vehicle accident or repetitive work activity.. Physical exam: True neurogenic and vascular TOS are uncommon, and such a ...
I may think its an occipital headaches but I could be wrong. I am 31 years old female who loves to exercise to the extreme. I am very into fitness and as a matter of fact Im considering joining a fit...
Synonyms for C2 in Free Thesaurus. Antonyms for C2. 8 synonyms for axis: pivot, shaft, axle, spindle, centre line, bloc, axis vertebra, axis of rotation. What are synonyms for C2?
Chiu CK, Chan CYW, Saw LB, Kwan MK. 2010. Scarf related Hangmans fracture: a case report. European Journal of Trauma and Emergency Surgery 36 (2):180-182. (SCOPUS-Cited Publication) Chan CYW, Kwan MK, Saw LB. 2010. Safety of thoracic pedicle screw application using the funnel technique in Asian: a cadaveric evaluation. European Spine Journal 19(1):78-84. (ISI/SCOPUS Cited […]. ...
Hi Nancyapplg8, I have a double curve scoliosis discovered at 13. In 1978, I had Harrington rod surgery to stabilize things. In 1996, because of more pain, I had a single fusion, then single fusions every year for 5 years. Then in 2003, the doctor fused remaining vertibra, so I am totally fused to middle of my neck. Then in 2010, I fell out of bathtub and broke my C2, a hangmans fracture, so now I am really totally fused! All this to say even tho I have chronic pain between my shoulder blades and my entire neck, I am glad I had the surgerys done, because I would be in even worse shape if I had done nothing. My lungs and heart would be involved because of the top curve twisting too. The only advise I can give is to find a doctor with a lots of experience, cause their patients have better outcomes. And expect there to still be pain. Be as active as possible after you heal. I am pretty sedentary and so part of my pain is of my own doing. I am 68 years old, and go regularly to a pain clinic. I am ...
Headsman On this date in 1908, John Boyd managed six fitful hours of sleep, had a breakfast of toast, poached eggs and tea, and then went to the Don Jail gallows for murdering his paramours rival suitor.. Canada had long before ceased public executions. Prior to Boyds execution, Don Jail hangings had occurred in a jail yard - technically behind prison walls, but easily peeped upon by curiosity-seekers willing to obtain higher ground. Boyds execution introduced a new privacy measure: it was the first of 26 hangings to occur in an interior chamber completely away from public eyes, the same place where Canada eventually held its last hangings in 1962.. But apart from this minor milestone, we notice on this date the hurried and disturbed departure of prolific hangman John Radclive. "Another poor soul gone," he was overheard to say as he left.. Radclive is the subject of an empathetic Toronto Star profile thats well worth the read.. He was Canadas first professional hangman, with 69 recorded ...
Would that I could be the peacemaker in your soul that I might turn the discord and the rivalry of your elements into oneness and melody ...
Would that I could be the peacemaker in your soul that I might turn the discord and the rivalry of your elements into oneness and melody ...
As a biologist, I firmly believe that when youre dead, youre dead. Except for what you live behind in history. Thats the only afterlife - J. Craig ...
Following the assassination of Nazi Heydrich, Masha Novotny, a professors daughter, hides the culprit in her parents apartment. When the Gestapo take 400 p
Free flashcards to help memorize facts about Muscles of Respiration and Muscles of the Spine. Other activities to help include hangman, crossword, word scramble, games, matching, quizes, and tests.
Free flashcards to help memorize facts about Anatomy & Physiology Fall 2016 FINAL EXAM Review: 1/Atlas, 3, 5, 6, 7 and 8. Other activities to help include hangman, crossword, word scramble, games, matching, quizes, and tests.
Nice to see you popping by the Diverticular team. It has been pretty quiet over there, and I didnt get notified about your wall post. Please do pop by again, and maybe join our hangman game? It would be lovely to see you there. I think KP must be getting fed up with playing on her own ...
J:176262 Giros A, Grgur K, Gossler A, Costell M, alpha5beta1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice. PLoS One. 2011;6(7):e22002 ...
Traumatic injuries of the upper cervical spine are often encountered, and may be associated to severe neurological outcome. This is a retrospective study of 70 patients, admitted over a 14 years period (1996 to 2010), for management of upper cervical spine injuries. Data concerning epidemiology, radiopathology and treatment was reviewed, and clinical and radiological evaluation was conducted. Men are more affected than women, with traffic accidents being the major traumatic cause. A cervical spine syndrome of varied intensity was found in about 90% of patients; neurological deficit was noted in 10 patients (21%). Radiological analysis discovered varied and many combined lesions: C1-C2 dislocation (7 cases), C2-C3 dislocation (9 cases), C1 fracture (10 cases) and C2 fracture (44 cases) including 28 odontoid fractures. Orthopedic treatment was carried out exclusively for 31 patients, and surgical treatment for 38 patients. One patient died before surgery because of a polytraumatisme. Posterior approach
Atlantoaxial instability implies excessive movement between the first cervical vertebra or atlas, and second cervical vertebra or axis.
Read "Feasibility and outcome of stand-alone trans-articular screw fixation in atlantoaxial instability in children less than 8years of age, European Spine Journal" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
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The application of laminar screws is an alternative fixation for the first thoracic vertebra (T1). This paper is to determine the anatomical characteristics for adequate laminar screw fixation, and present a modified method of sagittal reconstruction of T1 to provide more accurate measurements. Computed tomography (CT) images of 62 patients (32 males, 30 females) were used for the analysis. The following parameters of the T-1 lamina were measured using Mimics software: lamina length, axis angle, minimal outer cortical width, cancellous width, minimal outer cortical height, cancellous height, and spinous process height. Right or left modified sagittal reconstructions (parallel to right or left screws) were innovatively used for measurement. There were no significant differences between the left and right sides for each measurement performed (P | 0.05), but significant differences were detected between males and females (P | 0.05). The mean length of the T1 lamina was 32.8 mm of the T1 minimal outer
Diagnosis Code S12.100B information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
1]3,415 words. Part 2 of 3. "Here Punch does a mean trick, very unworthy of his Satanic character. He tells the hangman that he has never been hanged before; and though he would be only too glad to be hanged he does not know which way to put his head into the loop, and asks the hangman to show him, which he does. And Punch suddenly fools the rope, and the hangman, who is the sole representative of legal vindication, is himself hanged! Hangman hanged, all law and authority defied, and every restraint annulled, Punch bursts out into triumphant song." - Count Eric Stenbock, The Myth of Punch, edited by David Tibet (London: Durtro Press, 1999). "American politics used to be fun. Powerful men making decisions. Now its just who has the most money and avoiding decisions." - Comment at Classic Film and TV Café, February 2, 2012. In Part One of this essay ("Mad Men [2] Jumps the Gefilte Fish [2]"), we suggested that just as long-running pop culture items, especially television series, will eventually ...
Release dates for Cognition: An Erica Reed Thriller - Episode 1: The Hangman (iPad) database containing game description & game shots, cover art, credits, groups, press, forums, reviews and more.
OBQ09.111) An 11-year-old male complains of one year duration of neck pain. He denies any recent trauma. He has noticed intermittent episodes of gait imbalance and difficulty with buttoning his shirt over the past 3 months. Physical exam shows normal strength in all four extremities and hyper-reflexic patellar tendons. Neutral and flexion radiographs are shown in Figures A and B. A sagittal CT scan is shown in Figure C with a coronal reconstruction shown in Figure D. What is the most appropriate treatment? Review Topic , Tested Concept ...
For Cognition: An Erica Reed Thriller Episode 1 - The Hangman on the PC, GameRankings hosts box shots and game information and articles.
Auto Collision Differential Assessment, Whiplash trauma, post concussion syndrome, headaches, sinus infection, skull fracture, menigeal nerve damage, cervical nerve stimulating spinal nucleus of cranial nerve 5, greater occipital nerve compression, post trauma migraine, temporal mandibular joint dysfunction, sub occipital headaches, facet joint pain as a referring source, brain and brain stem related symptoms, concussive memory loss, lobe of brain disorders, vertebral artery trauma, carotid artery trauma. Daniel P. Dock., D.A.C.A.N., D.A.B.C.O., F.A.C.O., Boise, ID, 2012. Documentation and Triage in Trauma, ICD-9 and CPT requirements in coding for the traumatically injured including integrating electronic health records including informed consent, evaluation and management, testing orders. The utilization of research in medical reports for both the trauma and non-trauma patients. Clinical coordination of care and reporting to healthcare and legal providers. Federation of Chiropractic Licensure ...
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This is one of many cross sections from a CT (computed tomography) scan in a person who sustained a severe fracture of C2 (second cervical vertebrae). Bone in this CT image is the white density in the middle of the image. The fracture of C2 is seen as a disruption of this white density. - Stock Image M330/1254
From this, you can easily duplicate my algorithm by determining which letter to choose based on which word appears in the most candidate words (highest probability of being right) and break ties by using the highest overall density. You should however be able to do so much more. There are a couple of main approaches that I can think of. First, a 1 size fits all algorithm that weighs various different pieces of data to produce an overall score. The advantage here is that you should be able to tune these weights without touching code to produce the best results for a given "dictionary". The second approach would be to have multiple algorithms already fine tuned for a given set of conditions and dispatch to that algorithm based on initial conditions. For instance, it may be ok to take a risk of guessing wrong if the remaining wrong guesses is still high or perhaps utilize the "simple" algorithm already presented unless the probabilities and candidates remaining (if right or wrong) is beyond some ...
BATON ROUGE -- Trying to intimidate someone with a hangmans noose, a symbol of racial lynchings in the Old South, will be a crime in Louisiana if Gov. Bobby Jindal goes along with legislation unanimously passed by the House and Senate. House Bill 726 by Rep. Rickey Hardy, D-Lafayette, will make it a crime for a person to place a hangmans noose, or a picture of one, on another persons property or on public property with "the intent to intimidate." Conviction could bring fines up to $5,000 and up to a year in prison. A 37-0 vote in the Senate late Monday, following a 97-0 House vote earlier in the legislative session, sent the measure to Jindal for his signature. His office did not immediately respond Tuesday to a request for comment on the bill, which is modeled after an existing law outlawing cross burning. There was little discussion in either chamber but Hardy, during a committee hearing on the bill in May, noted the nooses history as a symbol of racial lynchings. - The ...
Where available, study the preparation material through the Info Page, flash cards, hangman, multiple-choice and match the column formats. Then, test your recall of the material through the fill in the blanks format. In some activities, reverse quiz is available where questions become the answers, and answers become the questions. ...
Edifying, controversial (Poz Normal, but no Stooges, no Roxy? Nearly God, not Maxinquaye?! Diamond Day rather than Hangmans Daughter?!?!?!) and scan-tastic: Woebot picks his top 100 records of all time (part one, part two, part three, part four, part five ...
List of 5 disease causes of Atlantoaxial instability causing neck stiffness and torticollis, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or symptoms for Atlantoaxial instability causing neck stiffness and torticollis.
In the present study, we investigated bone geometry, microstructure, and volumetric bone mineral density (vBMD) in a cohort of patients with nonradiographic axial spondyloarthritis (nr-axSpA) in order to define the early bone changes occurring in axial spondyloarthritis (axSpA) and to define potential factors for deterioration of bone microstructure. Patients with axSpA (n = 107) and healthy control subjects (n = 50) of similar age and sex were assessed for geometric, volumetric, and microstructural parameters of bone using high-resolution peripheral quantitative computed tomography (HR-pQCT) at the radius. Additionally, demographic and disease-specific characteristics of patients with axSpA were recorded. Patients with nr-axSpA and control subjects were comparable in age, sex, and body mass index. Geometric and microstructural analysis by HR-pQCT revealed a significantly reduced cortical area (p = 0.022) and cortical thickness (p = 0.006) in patients with nr-axSpA compared with control subjects. Total
This is the first case report of a traumatic odontoid process synchondrosis fracture in a calf. Neurological examination was useful for early and correct neuroanatomical localisation. Radiography was easy to perform and allowed an initial diagnosis. MRI and CT examination (although performed post-mortem for scientific interest) were helpful for sub-classifying the fracture type, excluding additional (traumatic or congenital) cervical lesions and, potentially, allowing better planning of potential surgical interventions. However, as evident in our case, transportation to the advanced diagnostic imaging site incurred the risk of further displacement and neurological deterioration, suggesting that the benefits versus risks of any procedure and transport should be carefully considered.. So far, detailed classification systems of atlantoaxial fractures are lacking in veterinary medicine. In humans, several classification systems for odontoid process fractures have been established but are still a ...
Non-radiographic axial spondyloarthritis causes inflammation in the spine, which can lead to back pain. Learn what causes this type of arthritis, how its treated, and what to expect.
A post treatment MRI showed significantly less fluid accumulation on McMahons brain. McMahon commented that the procedure "kept me from having bad pains and suicidal thoughts, and having me function fairly normally.". Following the chiropractic upper cervical spine adjustment, in July 2016, Jim McMahon was participating in the Tahoe South Celebrity-Am golf event when a Sacramento Bee sports reporter caught up with him for a story (6). The interview mentions that McMahon was one of the original plaintiffs in the concussion lawsuit that former players filed against the NFL. When questioned about his pain, fatigue, and brain function, McMahon replied:. "Ive got my good days and bad. As long as I keep my neck and head in alignment, Im fairly normal.". The article notes that McMahon visits a chiropractor in New York every two or three months to keep everything lined up, stating:. "It keeps the spinal fluid flowing properly. When it gets out of whack, all I want to do is lay down in a dark ...
Advanced Nondestructive Evaluation I: Moment Prediction for Evaluating Stability of the Upper Cervical Spine Fixed with Wires Using Finite Element Analysis
orthosis, 2 with a Minerva brace, and 1 with a halo. Two patients required cervical surgery; an occipital cervical fusion for a type 2 odontoid fracture and one atlantoaxial fusion for atlantoaxial instability was performed. At the follow up appointments, none of the patients were found to have delayed instability based on clinical examination, upright x-rays or flexion-extension x-rays. Conclusion: All isolated OCF are likely stable injuries. Our data suggests all isolated OCF may be treated conservatively with any type of cervical orthosis and minimal follow up. ...
The TMJ moves due to the contraction of the masseter, temporalis and pterygoid muscles. Their tone is controlled by the brain-stem housed by the ATLAS. TMJ is highly correlated to the upper cervical spine injury. The muscles of mastication are controlled by the fifth cranial nerve.
ABSTRACT. Extradural vertebral artery dissection is a condition with a generally good prognosis if it is promptly recognized and treated. Diagnosis and consequently therapy delay may cause extensive ischemia with catastrophic consequences, due to embolism from the thrombus in the vessel wall or its extension. Considering these aspects and also its low incidence, the identification and treatment of this condition must be immediate, all the more, so as its onset is deceitful by occipital headache and neck pain. The association between vertebral artery dissection and dental procedures has been previously noticed. This paper aims to describe the etiopathogenesis and clinical recognition of dental chair vertebral artery dissection for a prompt neurosurgical intervention, in order to have a good prognosis. ...
Head pain at base of skull - Daily occipital headaches, pulse in head, pain at base of skull rt side, muffled hearing, dizzy looking. Causes Headaches. The cause of the headaches are variable. Inflammation if the occipital nerve, a pinched nerve in the cervical spine, TMJ disorder, and mastoiditis are leading contenders. See a headache expert to determine the type of headache and to develop a course of treatment.
As with the two above, Id be more worried about the neck, and more specifically damage to the vertebral artery. From that article: The typical presentation of vertebral artery dissection (VAD) is a young person with severe occipital headache and posterior nuchal pain following a recent, relatively minor, head or neck injury. The trauma is generally from a trivial mechanism but is associated with some degree of cervical distortion ...
A 43-year-old man presented with acute-onset hemianesthesia involving the right arm, the right leg, and the right side of the face. Six weeks earlier, he had a moderate occipital headache that lasted for 3 days. Diffusion-weighted magnetic resonance imaging (MRI) of the brain showed a thalamic lesion of restricted diffusion on the left side (Panel A, arrow), which was consistent with acute posterior choroidal-artery infarction. T2-weighted MRI scans, a magnetic resonance angiogram, and a computed tomographic angiogram (Panels B, C, and D, respectively) revealed a dilatation of the left posterior cerebral artery, with a double lumen - that is, a true circulating lumen (Panels B, C, and D, lower arrows) and a false noncirculating lumen (Panels B, C, and D, upper arrows), divided by an intimal flap (Panel B, arrowheads), suggesting a dissecting aneurysm. Angiography confirmed an aneurysm of the posterior cerebral artery (Panel E, arrows). The patient reported no specific risk factor (e.g., trauma) ...
A 43-year-old man presented with acute-onset hemianesthesia involving the right arm, the right leg, and the right side of the face. Six weeks earlier, he had a moderate occipital headache that lasted for 3 days. Diffusion-weighted magnetic resonance imaging (MRI) of the brain showed a thalamic lesion of restricted diffusion on the left side (Panel A, arrow), which was consistent with acute posterior choroidal-artery infarction. T2-weighted MRI scans, a magnetic resonance angiogram, and a computed tomographic angiogram (Panels B, C, and D, respectively) revealed a dilatation of the left posterior cerebral artery, with a double lumen - that is, a true circulating lumen (Panels B, C, and D, lower arrows) and a false noncirculating lumen (Panels B, C, and D, upper arrows), divided by an intimal flap (Panel B, arrowheads), suggesting a dissecting aneurysm. Angiography confirmed an aneurysm of the posterior cerebral artery (Panel E, arrows). The patient reported no specific risk factor (e.g., trauma) ...
NTOS is induced by compression of the BP in any of 3 parts of the superior thoracic outlet: the interscalene triangle, costoclavicular space, or retropectoralis minor space.7 Paresthesia is the most common symptom,3 mostly evident in the ring and little finger.5,7 Pain is usually distributed in the shoulder region and radiates along the inner aspect of the arm. In severe cases, there may be atrophy of the thenar eminence, ulnar intrinsic hand musculature, and forearm muscles.10 Patients may present with symptoms of upper plexus compression (C5-C7), like pain on the ipsilateral aspect of the neck or mastoid area or even occipital headaches.6,7 Pain may also radiate to the deltoid region, trapezius, and the rhomboid muscles; the upper pectoral region; and down the lateral aspect of the arm. In most cases, however, patients present with involvement of the lower plexus (C8-T1). Symptoms are usually aggravated by continuous elevation of the arm.5,7,13 However, because 99% of patients with NTOS lack ...
Male and female patients with axial spondyloarthritis experience the disease differently, researchers say. In a cross-sectional study of 466 patients from the ongoing observational Groningen Leeuwarden Axial Spondyloarthritis cohort patient reported measures of disease activity, physical function and quality of life were significantly worse for females. Writing in Rheumatology the researchers said the gender differences could […]
Overweight and obesity in axial spondyloarthritis is common and has a negative impact on disease activity, registry data shows. Lead author and rheumatology registrar Gillian Fitzgerald, from the St Jamess hospital in Dublin, Ireland, told ACR 2017 delegates there was a general perception that people with axial spondyloarthritis (axSpA) had a normal BMI. But her […]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
A prosthetic replacement for a posterior element of a vertebra comprising portions that replace the natural lamina and the four natural facets. The prosthetic replacement may also include portions that replace one or more of the natural spinous process and the two natural transverse processes. If desired, the prosthesis replacement may also replace the natural pedicles. A method for replacing a posterior element of a vertebra is also provided.
A prosthetic replacement for a posterior element of a vertebra comprising portions that replace the natural lamina and the four natural facets. The prosthetic replacement may also include portions that replace one or more of the natural spinous process and the two natural transverse processes. If desired, the prosthesis replacement may also replace the natural pedicles. A method for replacing a posterior element of a vertebra is also provided.
The obliquus capitis inferior is a fleshy, thick muscle located in the neck. It is the bigger and longer of the two oblique muscles in the neck. This muscle originates from the outer part of the spinous process of the second cervical vertebra, also called the axis.
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HENRIQUES Thomas , CUNNINGHAM Bryan W. , OLERUD Claes , SHIMAMOTO Norimichi , LEE Guy A. , LARSSON Sune , MCAFEE Paul A. Spine 25(22), 2877-2883, 2000-11-15 DOI 参考文献31件 被引用文献20件 ...
Heres the set-up, such as it is: The couldnt-be-more-British Berry - a whiskey-loving scoundrel with a rapist wit (no, really) and a silky smooth baritone vox - is employed as High Executioner to the King of England. He also may or may not be a direct descendant of Jack the Ripper. Fulcher - a moon-faced, socially awkward American with poor hand-eye coordination and a penchant for profoundly inappropriate bursts of surreal profanity - has somehow weaseled his way into a position as Berrys assistant, not to mention adjunct membership in the posh Hangman Gentlemans Club where much of the series takes place ...
For my dear brothers from the Group of the 75. They snatched me from the arms of Yolanda, from the heart of the family, and from the social environment. I am a hostage of intolerance, of repression, and of cynicism. Castro-ism and its hangmen, felony, demagoguery, and infamy all incriminate me. I am attacked by…
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TY - JOUR. T1 - Smoking does not protect patients with axial spondyloarthritis from attacks of uveitis. AU - Zhao, Sizheng Steven. AU - Macfarlane, Gary J. AU - Jones, Gareth T. AU - Gaffney, Karl. AU - Hughes, David M. AU - Moots, Robert J. AU - Goodson, Nicola J. N1 - The BSRBR-AS is funded by the British Society for Rheumatology (BSR) who have received funding for this from Pfizer, AbbVie and UCB.. PY - 2019/9. Y1 - 2019/9. N2 - Acute anterior uveitis (AAU) is the the most common extra-axial manifestation in axial spondyloarthritis (axSpA) and can lead to visual impairment if untreated. Cross-sectional axSpA studies have consistently reported lower odds of AAU in current smokers than ex or never smokers,1 2 which is in contrast to higher AAU risk among smokers in the general population.3 One explanation for this apparent paradox is behaviour change; those with AAU may be more likely to quit smoking. However, this does not explain the higher odds of AAU in never smokers. Another possibility is ...
Looking for online definition of atlantoaxial membrane in the Medical Dictionary? atlantoaxial membrane explanation free. What is atlantoaxial membrane? Meaning of atlantoaxial membrane medical term. What does atlantoaxial membrane mean?
Excessive movement between atlas and axis characterizes anterior atlantoaxial instability. At present, dynamic plain radiographs are the criterion standard in diagnosing AAA subluxation. The atlas slips abnormally forward during flexion because of laxity or rupture of the transverse and alar ligaments. The atlas slips backward when the cervical spine is in the neutral or extension positions. A few studies have reported MR imaging findings of AAA subluxation,8,9 but none has focused on the diagnostic implications of abnormalities in the associated structures or suggested a method to improve the false-negative diagnostic rate in nAAA subluxation patients. To our knowledge, this study is the first attempt to do so.. Routinely cervical spine MR imaging is performed with supine and neutral positioning. With this positioning, gravity pulls the subluxated atlas backward and downgrades the severity of disease on MR images. In our study, x-ray radiographs with neutral positioning yielded a 28% (11 of 40) ...
In this study, 39 % of patients referred to rheumatology clinics with CLBP met the ASAS criteria for IBP. Further, 29 % of patients with IBP met the criteria for nr-axSpA. The proportion of axial SpA patients with nr-axSpA was within the range (23-80 %) reported in the literature [4, 8], though on the lower end of prior estimates.. Our data suggest a higher percentage of males among patients with nr-axSpA (64 %) relative to the percentages in other published noninterventional studies (34-50 %) [9, 10] and most clinical trials (48-64 %) [11-16]. There were a number of methodological differences across these studies (e.g., inclusion and exclusion criteria, country), but it is unclear which of these factors would help to explain the differences in results. Further research is necessary.. We found that patients with nr-axSpA were the youngest, and they experienced CLBP for the shortest duration at slightly over 6 years compared with nearly 11 years for patients with AS. Although no age differences ...
TY - JOUR. T1 - Wnt3a links left-right determination with segmentation and anteroposterior axis elongation. AU - Nakaya, Masa Aki. AU - Biris, Kristin. AU - Tsukiyama, Tadasuke. AU - Jaime, Shaulan. AU - Rawls, J. Alan. AU - Yamaguchi, Terry P.. PY - 2005/12. Y1 - 2005/12. N2 - The alignment of the left-right (LR) body axis relative to the anteroposterior (AP) and dorsoventral (DV) axes is central to the organization of the vertebrate body plan and is controlled by the node/organizer. Somitogenesis plays a key role in embryo morphogenesis as a principal component of AP elongation. How morphogenesis is coupled to axis specification is not well understood. We demonstrate that Wnt3a is required for LR asymmetry. Wnt3a activates the Delta/Notch pathway to regulate perinodal expression of the left determinant Nodal, while simultaneously controlling the segmentation clock and the molecular oscillations of the Wnt/β-catenin and Notch pathways. We provide evidence that Wnt3a, expressed in the primitive ...
From the eMedicine site: The typical presentation of VAD is a young person with severe occipital headache and posterior nuchal pain following a recent, relatively minor, head or neck injury. The trauma is generally from a trivial mechanism but is associated with some degree of cervical distortion. Focal neurologic signs attributable to ischemia of the…
Rosette-forming glioneuronal tumor (RGNT) is a rare variety of slow growing mixed glioneuronal tumor involving primarily fourth ventricular region and occurring predominantly in young adults. We present a case of a 16-year-old boy who presented with dizziness and occipital headache. On radiological evaluation, a fairly large hypodense posterior fossa mass lesion in relation to the left side of the vermis, with a large cystic component was found. Surgical resection of the tumor was performed. Histopathological examination showed a biphasic tumor composed of bland neurocytic cells, arranged in the form of neurocytic rosettes along with glial areas resembling low-grade glioma ...
This pattern exhibits the following symptoms: fever, chills (these are worse than the fever), inability to get warm, nasal or sinus congestion with clear mucus, cough with clear mucus, stiff neck and shoulders, occipital headache (back of head), and a slower-than-normal pulse that is more easily felt at the surface.. Diaphoretic (sweating) therapy is especially helpful in this condition, since it warms the body and pushes the pathogen out through the pores. In the very early stages of this pattern, an effective remedy is miso soup with the white part of spring onion (cong bai) and fresh ginger (sheng jiang). For more severe or advanced cases, there is a full range of therapies, depending on the combination of symptoms.. When the wind-cold symptoms include strong chills, inability to sweat, wheezing, and stiff neck, the classic and ancient remedy is Ephedra Decoction (Ma Huang Tang). The chief herb in this formula is Ephedra (ma huang), a powerful stimulant that opens the bronchial passages, ...
To the editor: In 1960 Vogt (1) called attention to the possible presence of elevated alkaline phosphatase levels in thyroiditis. Since the report of Dalovisio (2) last year, a number of letters confirming their finding have appeared.. We wish to report one case of subacute thyroiditis with serum levels of alkaline phosphatase only minimally raised, but in which the thermoestable fraction was markedly elevated, indicating a hepatobiliary origin.. A 35-year-old woman began to feel nervousness, tremor, occipital headache and pain in the anterior aspect of the neck around 3 March 1979. By 1 month later, she had developed fever (temperature ...
The Berlin modification of the ASspiMRI-a is a scoring system with a concentration on Short-Tau-Inversion Recovery (STIR) sequences without other fat saturation techniques. It quantifies changes in 23 Vertebral Units (VU) of the spine. A VU is defined as the region between 2 virtual lines through the middle of each vertebra. Active inflammation is scored by grading the degree of bone marrow edema from 0 to 3 in 1 dimension on 1 or more consecutive slices that represent the highest level of inflammation in a particular VU. Total spine ASspiMRI-a score in the Berlin modification can range from 0 to 69 with higher scores indicating higher disease activity. A negative value in total spine ASspiMRI-a score change from Baseline indicates an improvement from Baseline. The higher the negative value the higher the reduction of inflammation ...
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Conclusions This study has allowed to analyze the areas that are more often damaged in AS patients as it increases the degree of structural damage. The most affected are those belonging to the middle of the cervical and lumbar region (C5 and L4). The mSASSS index was higher in men than in women, a fact already known. The mobility according UCOASMI was decreasing as structural damage increases. The ASDAS index was similar in all groups (although statistical differences between men and women were found). Following a logical structure (sclerosis, quadrature, syndesmophyte and bone bridge) the vertebrae most commonly affected should have a greater presence of spinal fusion, however, according to the ratio of severity, are not the central but the extreme vertebrae which have a higher severity ratio. Especially in those vertebrae that have less mobility, bone bridges appear earlier. This can highlight the idea of the need of increased physical activity and exercise adequate flexibility in these ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
The Author(s). 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated ...
The suppleness of the poll is in direct relation to the suppleness of the back. You cannot have one without the other. Many times the horse has learned to be "obedient" to the bridle but the rider may feel a resistance in the horses hindquarters or the shoulders, when actually the cause of the problem is in the horses mouth. In dressage horses, for instance, if the jaw is locked the horse will be inclined to give at the first/second cervical vertebrae giving a "false bend" to relieve the pressure on his jaw. This restricts his ability to fully engage the rest of his body and limbs. In speed events such as racing, barrel racing or even cutting, if there is any pain or restriction in the mouth and jaw area, it can cause head tossing, lack of concentration, shortening of stride and weakened hocks. Weakened hocks may cause front leg injuries because the horse is more inclined to pull himself along with the front legs rather than to push himself from the hind legs. Jumpers and hunters need to have ...
You could say that form is learning. you can see form take shape. at the coronal sutures first arcade. its explaining its appearing. its unestranged from enormitys. prick of a spiny plant like a rose as. experimenting its bursting and. usually its repeating why is form. a dog as a horse as a deer as a. fish and a bramble a grater rapacious. the second cervical vertebrae is. repeating is a question we can. ask with our bodies and what is. a tooth coccyx is the beak of an ancient. dove below the sacrum the tip of. the sacrum places in the person a. sensation of slow form repeating it. doesnt require its own skin to repeat. fox a foxtail a lizard as psoas. a small flask of modern oil at the throat. the repeat carries between bodies. whats made in this space are theories. and thymus a rising of beneficial. smoke as thorax as guitar the hairs. exact and between bodies forms not. ever without a stupendous body so. the repetition is never exact. this is why form is always learning. how as it ...
Dr. The primary afferent nociceptor. Recently, tezars etal demonstrated that the procedure for screening sidebending t to t. Vaginalis, so additional doses may be allowed to rise to the transverse colon fig. Though a patient for evidence of atlantoaxial instability may develop. The emergency management of pain, if a bat in the form of nonparametric or parametric statistical tests available.
Old Anderson II fracture with dorsal dislocation of the dens axis and subluxation of the atlanto-axial joints. The spinal cord is not affected. ...
There are no berths for yachts at the fish quay.. New Grimsby Sound Anchor between Hangman Island and the quay. Good shelter except in NW winds.. There are 22 visitors buoys here.. Close to the quay, there is a public toilet and a water tap by the shed.. There is a pub and cafe/restaurant on the island.. NOTE There is no garbage disposal on this island, but there is on Tresco.. Last updated February 2016. ...
In the midst of them, the hangman, ever busy and ever worse than useless, was in constant requisition; now, stringing up long rows of miscellaneous criminals; now, hanging a housebreaker on Saturday who had been taken on Tuesday; now, burning people in the hand at Newgate by the dozen, and now burning pamphlets at the door of Westminster Hall; to-day, taking the life of an atrocious murderer, and to-morrow of a wretched pilferer who had robbed a farmers boy of sixpence ...
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AXIS BANK RAYAGADA IFSC Code: IFSC Code for AXIS BANK RAYAGADA on The Economic Times. Find AXIS BANK RAYAGADA MICR Code, AXIS BANK RAYAGADA IFSC Code, Branch Address for all AXIS BANK Branches across RAYAGADA.
Background Based on ASAS axial spondyloarthritis (SpA) criteria, the presence of structural changes of sacroiliac (SI) joints such as sclerosis, bone erosion, joint space widening or ankyloses dose not meet the definition of active sacroiliitis on magnetic resonance imaging (MRI), if there is no bone marrow edema (BME). However only less than half Asian patients with SpA were characterized by BME. Neither serum inflammatory markers such as c reactive protein (CRP) nor erythrocyte sedimentation rate (ESR) is able to be useful as diagnostic markers in the early phase of SpA. HLA-B27 is associated with early diagnosis of SpA and axial inflammation of SI joints on MRI. Nonetheless, HLA-B27 is not associated with structural lesions of SI joints. All factors contribute to difficult defining early Asian SpA patients in the absence of serum HLA-B27 and active imaging inflammation. ...
1. Which statement about the cervical spine and its injuries is true?. a. Less than one half of spinal cord injuries result from cervical spine fractures.. b. The upper cervical spine isdefined as extending from C1 through C3.. c. Seventy-five percent (75%) of cervical spine injuries occur in the upper cervical spine.. d. The most common area of cervical injury is C3 to C7.. 2. Which statement best reflects current thinking about imaging studies for cervical spine evaluation?. a. Radiographic films should always be performed initially.. b. Computed tomography (CT) scans should always be first-line studies.. c. There is controversy whether radiography or CT scan should be performed first.. d. Magnetic resonance imaging (MRI) is not needed to examine cervical spine injuries.. 3. The teardrop fracture. a. is a stable fracture.. b. involves disruption of all 3 spinal columns.. c. results from forceful flexion with compression.. d. is difficult to visualize on plain radiographs.. 4. Management of a ...
Methods and Findings: A 51-year-old woman with a history of neck pain, hyperlipidemia, headaches, and fibromyalgia presented to a local emergency department with new occipital headache radiating to the face 1 week after a cervical epidural steroid injection on 31 August 2012 (Chen L, Lyons JL. Personal communication.). She had not received injections previously, had no history of immune compromise or trauma, and was not taking any long-term medications. Physical examination and unenhanced head computed tomography were normal, and she was discharged. No lumbar puncture was performed. She returned the next day with diplopia, vertigo, nausea, and ataxia and was hospitalized. Physical examination was notable only for hoarseness and decreased tendon reflexes; routine serum chemistry and blood counts were normal, and she had no fever. Magnetic resonance imaging (MRI) of the brain on hospital day 1 was normal. By day 3, she remained afebrile but developed slurred speech, right hemiparesis, left facial ...
Definition of epistropheus in US English - The axis (second cervical vertebra). In early use also: †the atlas (first cervical vertebra) (obsolete).
Description of disease C1 (cervical vertebra). Treatment C1 (cervical vertebra). Symptoms and causes C1 (cervical vertebra) Prophylaxis C1 (cervical vertebra)
Spinous process C3 aka Processus spinosus C3 in the latin terminology and part of axial ct at the level of the second cervical vertebra (axis). Learn more now!
In THE HATEFUL EIGHT, set six or eight or twelve years after the Civil War, a stagecoach hurtles through the wintry Wyoming landscape. The passengers, bounty hunter John Ruth (Russell) and his fugitive Daisy Domergue (Leigh), race towards the town of Red Rock where Ruth, known in these parts as "The Hangman," will bring Domergue to justice. Along the road, they encounter two strangers: Major Marquis Warren (Jackson), a black former union soldier turned infamous bounty hunter, and Chris Mannix (Goggins), a southern renegade who claims to be the towns new Sheriff. Losing their lead on the blizzard, Ruth, Domergue, Warren and Mannix seek refuge at Minnies Haberdashery, a stagecoach stopover on a mountain pass. When they arrive at Minnies, they are greeted not by the proprietor but by four unfamiliar faces. Bob (Bichir), whos taking care of Minnies while shes visiting her mother, is holed up with Oswaldo Mobray (Roth), the hangman of Red Rock, cow-puncher Joe Gage (Madsen), and Confederate ...
Cervical Collar (Boneless) - RH109 - We are manufacturer and suppliers of RH109 Cervical Collar (Boneless) and other Cervical Support.. Product Details & video of this product .. Narang Medical Limited, New Delhi, India
SOMI Brace - Sternal-Occipital-Mandibular-Immobilizer, a brace for the cervical thoracic spine. It provides greatest immobilization for the mid and lower cervical spine. It immobilizes the upper cervical spine to a lesser degree.. ...
Its time to give your neck a break! Not literally of course! But after a long day of work and stress you will want to have one of these absolutely amazing cervical collars. Our fast paced world can take a toll on our bodies and our neck will be one of the first areas where you feel the wear and tear of poor posture, physical tension, and even emotional stress.
Balego & Associates Inc. - BalegoOnline.org Cervical Collar, PED 2-7 yrs Fits Neck: 10 - 12 [11-121] - Soft foam treated with Microban® Anti-Microbial Protection for a fresher, more hygienic productLow contour maintains head in neutral positionSimple application with hook and loop closuresHCPCS Code: L0120Series Sizes Approx.Age FitsNeck CollarWxL 11-121 PED 2-7 yrs 10 - 12 2 1/2 x 15
Medikabazaar is Indias largest B2B marketplace for Medical Devices and Medical Supplies. Buy Flamingo Cervical Collar OC-2003 (Small) at best price and get doorstep delivery. Shop now and get best deals on all products.
We confirmed a similar burden of disease (as determined by self-reported disease activity, impaired function, and quality of life) in patients with nonradiographic axial SpA (n = 232) and those with radiographic axial SpA (n = 838). Patients with radiographic axial SpA had higher median levels of acute-phase reactants and higher median AS Disease Activity Scores (ASDAS; 3.2 versus 3.0). Anti-TNF treatment was initiated in 363 patients with radiographic axial SpA and 102 patients with nonradiographic axial SpA, preferentially in those with sacroiliitis on magnetic resonance imaging, peripheral arthritis, a higher C-reactive protein (CRP) level, a higher ASDAS, and a higher Bath Ankylosing Spondylitis Disease Activity Index level. The ASAS criteria for 40% improvement responses at 1 year were higher in patients with radiographic axial SpA compared with those with nonradiographic axial SpA (48.1% versus 29.6%; odds ratio [OR] 2.2, 95% confidence interval [95% CI] 1.12-4.46, P = 0.02). The ...
spine glossary craniocervical junction craniocervical junction. this is aplex region where the skull and upper cervical spine connect. the connection between the brain and the spinal cord is at the base of the brainstem in the region of the craniocervical junction.cervical spine anatomy overview gross anatomy the cervical spine is m up of 7 vertebrae. the first 2 c1 and c2 are highly specialized and are given unique names atlas and axis respectively. c3c7 are more classic vertebrae having a body pedicles laminae spinous processes and facet joints. c1 and c2 form a unique set of articulationsupper cervical spine disors anatomy of the head and upper cervical spine disors anatomy of the head and upper neck a quick lesson to help you learn more about your craniovertebral junction condition.craniocervical junction disors brain spinal cord the craniocervical junction consists of the bone that forms the base of the skull occipital bone and the first two bones in the spine which are in the neck the ...
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China Posterior Cervical Vertebra Fixation, Find details about China Posterior Cervical Vertebra Fixation, Spine Fixer from Posterior Cervical Vertebra Fixation - Suzhou Gemmed Medical Instrument Co., Ltd.
Hooch, Chances are the chiropractor you were seeing before practiced a full spine technique. Even with him being a full spine chiropractor there is no reason why he shouldnt have adjusted your neck just because you were diagnosed with RA. ...

Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA...Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA...

Swap70b morphants exhibited broader and shorter body axis but cell fate specification appeared normal. While ectopic Swap70b ...
more infohttp://eprints.nottingham.ac.uk/2917/

Kisspeptins (KiSS-1): Essential Players in Suppressing Tumor Metastasis
				-Asian Pacific Journal of Cancer Prevention
			
...Kisspeptins (KiSS-1): Essential Players in Suppressing Tumor Metastasis -Asian Pacific Journal of Cancer Prevention ...

Dhillo WS, Chaudhri OB, Patterson M, et al (2005a). Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human ... Smith JT, Clifton DK, Steiner RA (2006). Regulation of the neuroendocrine reproductive axis by Kisspeptin-GPR54 signaling. ... comparative aspects and roles in the control of female gonadotropic axis in mammals. Gen Comp Endocrinol, 153, 132-40. https:// ...
more infohttp://koreascience.or.kr/article/JAKO201305981338335.page

Borderline Personality Disorder | CMHA Cariboo Chilcotin BranchBorderline Personality Disorder | CMHA Cariboo Chilcotin Branch

1998). Axis I comorbidity of borderline personality disorder. American Journal of Psychiatry, 155(12), 1733-1739. ...
more infohttp://cariboo.cmha.bc.ca/documents/borderline-personality-disorder-2/

Traumatic odontoid process synchondrosis fracture with atlantoaxial instability in a calf: clinical presentation and imaging...Traumatic odontoid process synchondrosis fracture with atlantoaxial instability in a calf: clinical presentation and imaging...

Repair of fractured dens of the axis in a foal. J Am Vet Med Assoc. 1978;173(7):854-6.PubMedGoogle Scholar. ... Axis fractures: a comprehensive review of management and treatment in 107 cases. Neurosurgery. 1985;17(2):281-90.View Article ... Fractures of the odontoid process of the axis. J Bone Joint Surg Am. 1974;56(8):1663-74.PubMedGoogle Scholar. ... Gygax D, Furst A, Picek S, Kummer M. Internal fixation of a fractured axis in an adult horse. Vet Surg. 2011;40(5):636-40.View ...
more infohttps://irishvetjournal.biomedcentral.com/articles/10.1186/s13620-015-0034-5

Talk:Blood Axis - WikipediaTalk:Blood Axis - Wikipedia

Blood Axis is a controversial music group founded by Michael Moynihan in 1989. Blood Axis have been depicted as fascists, and ... I plan on totally revising this article so that it retains those aspects of Blood Axis that have raised the ire of specific ... Musically, Blood Axiss amalgamation of classical music, folk and industrial owes a debt to Boyd Rice, Wagner and Prokiev. ... It is merely an overview of Blood Axis and their significance to the traditional folk music scene. ...
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Gut-brain axis - WikipediaGut-brain axis - Wikipedia

HPA axis). That term has been expanded to include the role of the gut flora as part of the "microbiome-gut-brain axis", a ... including the hypothalamic-pituitary-adrenal axis (HPA axis), sympathetic and parasympathetic arms of the autonomic nervous ... As of October 2016, most of the work that had been done on the role of gut flora in the gut-brain axis had been conducted in ... That said, most of the work that has been done on the role of gut flora in the gut-brain axis has been conducted in animals, ...
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axis mundi  - Lulu.comaxis mundi - Lulu.com

The Elemental Horses - Axis Mundi By Diana Huang Paperback: List Price: $17.50 $12.25 , You Save: 30% ... The Advent of Dionysus: The Axis Mundi By Dennis Hamilton Paperback: List Price: $20.28 $14.20 , You Save: 30% ... The Mythology of the World Axis; Exploring the Role of Plasma in World Mythology By Marinus Anthony Van der Sluijs Paperback: $ ... The World Axis as an Atmospheric Phenomenon By Marinus Anthony Van der Sluijs Paperback: $6.30 ...
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axis of rotation | Encyclopedia.comaxis of rotation | Encyclopedia.com

The Earths axis of rotation is the line between the North and South geographic Poles, which precesses (see CHANDLER WOBBLE). ... Source for information on axis of rotation: A Dictionary of Earth Sciences dictionary. ... axis of rotation The line about which rotation occurs. ... axis of rotation A Dictionary of Earth Sciences © A Dictionary ... axis of rotation The line about which rotation occurs. The Earths axis of rotation is the line between the North and South ...
more infohttps://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/axis-rotation

Planes & axesPlanes & axes

... axis- X-Axis - Sagittal or (anterioposterior) axis- Z-Axis - Longitudinal axis- Y-Axis Movement, both whole body and segmental ... Anatomical Reference Axes(Axes is plural for axis)• An imaginary axis of rotation that passes through a joint to which it is ... Summary ofPlanes & Axes * 29. The cardinal axes lie at the Y Axisintersection of the cardinalplanes. Center of Gravity X Axis Z ... themovement takes place.Axis is the singular and axes are the plural noun.Any movement occurs in a plane around an axis.Axis of ...
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Jessica Kinni - Axis RadiusJessica Kinni - Axis Radius

... Profile , portfolio , Jessica Kinnis Photos Report this image. Email to a friend. Add to list. ...
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China axis camera wholesale 🇨🇳 - AlibabaChina axis camera wholesale 🇨🇳 - Alibaba

Source a Large Selection of Axis Camera Products at 3 axis gimbal ,6 axis robot ,5 axis cnc machine from China Alibaba.com ... China Axis Camera, China Axis Camera Suppliers and Manufacturers Directory - ... Related Searches for axis camera: 3 axis gimbal 6 axis robot 5 axis cnc machine cnc 5 axis axis ip camera cctv security camera ... A wide variety of axis camera options are available to you, such as paid samples, free samples. There are 18,586 axis camera ...
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Gut-brain Axis and PsychobioticsGut-brain Axis and Psychobiotics

www.dovepress.com/psychobiotics-and-the-gutndashbrain-axis-in-the-pursuit-of-happiness-peer-reviewed-fulltext-article-NDT ... forming in turn the gut-brain interaction called the gut-brain axis. This has given rise to the term psychobiotic, which ...
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Axis & Allies (2004) CheatsAxis & Allies (2004) Cheats

... * PC , Submitted by GamesRadar Various Cheats ...
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Discordance Axis - The Inalienable Dreamless (FULL) - YouTubeDiscordance Axis - The Inalienable Dreamless (FULL) - YouTube

... by Discordance Axis. Released on Hydra Head Records. One of the best grindcore albums out there. Its 24 minutes ... ... Mix - Discordance Axis - The Inalienable Dreamless (FULL)YouTube. * Discordance Axis ‎- Jouhou FULL ALBUM (1997 - Grindcore) - ... Discordance Axis ‎- Ulterior FULL ALBUM (1995 - Grindcore) - Duration: 17:43. Grind n Gore 23,407 views ... DISCORDANCE AXIS - 6/04/00 @ CBGBs, New York City, NY - Duration: 25:43. KILLTHATCATarchives 7,309 views ...
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Successful FDA Inspection at AXIS Clinicals USASuccessful FDA Inspection at AXIS Clinicals USA

AXIS Mexico (Est. 2010) and AXIS India (Headquarters, Est. 2004). AXIS USA offers the conveniences of a purpose-built 120,000 ... About AXIS Clinicals AXIS Clinicals USA, a full-service Contract Research Organization (CRO), is joined by other global sites, ... AXIS has completed 19 successful FDA inspections at our Hyderabad, India and Dilworth, MN sites for USFDA submission studies, ... The most recent audit focused on Dermatology which has been a business focus for AXIS since our inception and we have invested ...
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Overview | Axis CommunicationsOverview | Axis Communications

by visiting the Axis Experience Center in our Chicago, Illinois office. The Axis Experience Center is designed to provide an ... Each visit is unique to deliver the best possible Axis Experience for you. You will not only learn the value that Axis products ... The Axis Experience Center-Chicago is located on the border of Rosemont & Chicago, Illinois. We are within a 10 minute drive of ... The Axis Experience Center has a variety of features and opportunities available to complement your meeting. Some features ...
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Finland | Axis CommunicationsFinland | Axis Communications

For Axis corporate rates, please refer to Axis Communications Academy when you book your stay. ... The Axis Communications Academy trainings are held at Axis Headquarters in Lund, Sweden. ... Note: Axis reserves the right to cancel any event up to 10 calendar days prior to the start date. Notification of cancelled ... Axis Video Management Software training (Academy course description flyer)107 KB * Designing Network Video Solutiosn (Academy ...
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Axis Bank News - India Real Time - WSJAxis Bank News - India Real Time - WSJ

Enams the Prize for Axis Bank. *. Nov 18, 2010 1:32 pm IST. ...
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Decrepit Birth - Axis Mundi | Musicians FriendDecrepit Birth - Axis Mundi | Musician's Friend

Axis Mundi at Musicians Friend. Get a low price and free shipping on thousands of items. ... Alliance Decrepit Birth - Axis Mundi. Release Date:07/21/2017;Notes:Limited edition blue and yellow colored vinyl LP pressing. ... Alliance Decrepit Birth - Axis Mundi. Skip to main content Skip to footer /*#janrain-paypal { display:none; }*/ # ... Axis Mundi was recorded at 3 different studios over the course of a year. The clarity, the power, the musicianship, and the ...
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What is the Gut-Brain Axis?What is the Gut-Brain Axis?

This is also known as the gut-brain axis. ... Gut-Brain Axis and Neurodegenerative Disorders. *Gut-Brain Axis ... Lyte M. Microbial Endocrinology and the Microbiota-Gut-Brain Axis. In: Lyte M, Cryan JF, editors. Microbial Endocrinology: The ... through the neuroanatomical pathway of the gut-brain axis), but also through the immune system, endocrine system and metabolic ... Microbiota-Gut-Brain Axis in Health and Disease. Springer, 2014; pp. 3-24. ...
more infohttps://www.news-medical.net/health/What-is-the-gut-brain-axis.aspx

Axis Traction with Ordinary Forceps | The BMJAxis Traction with Ordinary Forceps | The BMJ

Axis Traction with Ordinary Forceps. Br Med J 1898; 2 doi: https://doi.org/10.1136/bmj.2.1982.1869 (Published 24 December 1898) ...
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Funeral industry axes ombudsman - TelegraphFuneral industry axes ombudsman - Telegraph

The consistent failure by the Office of Fair Trading to impose stricter controls on a clutch of troublesome service industries was highlighted last week by news that the funerals ombudsman service had been quietly axed at the end of September.
more infohttps://www.telegraph.co.uk/finance/personalfinance/2832576/Funeral-industry-axes-ombudsman.html?fbclid=IwAR16N5Jsydr5sQTuZwY_-dda5d48s23HxB7qZVxKX3T5wmy6hXfehL3EXXs

Italy-UK: Frattini, strong defence axisItaly-UK: Frattini, strong defence axis

In the sector of European defence "the Italo-British axis is certainly very strong. Italy has much to offer". This was the ...
more infohttps://www.esteri.it/mae/en/sala_stampa/archivionotizie/approfondimenti/20100721_italia_granbretagna.html

Automation Alley - Axis SystemsAutomation Alley - Axis Systems

Axis Systems is a part of Automation Alleys MASC program.. To learn more about how MASC can help your company, click here. ... Axis Systems is a stocking supplier of quality automation components. We specialize in Motion, Safety, Sensor and Vision ...
more infohttps://www.automationalley.com/Programs/MASC/Directory/Axis-Systems.aspx

What I taught today: Axis specification | ScienceBlogsWhat I taught today: Axis specification | ScienceBlogs

Next week I promised to start going into more detail, when we start talking about early fly development and axis decisions. The ...
more infohttps://scienceblogs.com/pharyngula/2013/02/04/what-i-taught-today-axis-specification
  • Cultural anthropologists often use the term 'axis mundi' in a looser sense than the strict astronomical one. (lulu.com)
  • By contrast, the mythological phenomenon loosely identified as the axis mundi dates back to the earliest stages of civilisation and is described by the most diverse cultures in remarkably similar terms. (lulu.com)
  • Axis Mundi was recorded at 3 different studios over the course of a year. (musiciansfriend.com)
  • 3. IntroductionThe plane : is the surface on which themovement occurs or takes place.The axis : is the line around which themovement takes place.Axis is the singular and axes are the plural noun.Any movement occurs in a plane around an axis.Axis of the same plane makes an angleperpendicular to that plane. (slideshare.net)
  • AXIS T93E05 Protective Housing is perfect for both indoor and outdoor cost-sensitive installations and wide-ranging applications, such as office buildings, gate surveillance, retail stores and service stations. (cdw.com)
  • US - FDA has recently completed its third inspection of AXIS Clinicals' USA for dermatology studies site with no 483 observations. (prweb.com)
  • The most recent audit focused on Dermatology which has been a business focus for AXIS since our inception and we have invested heavily to build our capabilities and serve our customer's needs. (prweb.com)
  • You will not only learn the value that Axis products offer, but also gain a better understanding of what it means to do business with Axis. (axis.com)
  • Because there is no factual evidence to link Blood Axis to white supremacist or racist ideologies, it is superfluous to cite that Mr. Moynihan has denied allegations that he is a Fascist and a White Supremacist. (wikipedia.org)
  • The term "gut-brain axis" is occasionally used to refer to the role of the gut flora in the interplay as well, whereas the term "microbiome-gut-brain axis" explicitly includes the role of gut flora in the biochemical signaling events that take place between the GI tract and CNS. (wikipedia.org)
  • That term has been expanded to include the role of the gut flora as part of the "microbiome-gut-brain axis", a linkage of functions including the gut flora. (wikipedia.org)
  • that part of the optic axis from the midpoint of anterior surface of the cornea to the posterior surface of the posterior pole of the external surface of the sclera. (drugs.com)
  • The gut-brain axis, a bidirectional neurohumoral communication system, is important for maintaining homeostasis and is regulated through the central and enteric nervous systems and the neural, endocrine, immune, and metabolic pathways, and especially including the hypothalamic-pituitary-adrenal axis (HPA axis). (wikipedia.org)
  • Axis Systems takes pride in Customer Service. (automationalley.com)
  • Axis Systems is a part of Automation Alley's MASC program. (automationalley.com)
  • The Axis Experience Center is designed to provide an exclusive experience with a hands-on, customized demonstration of Axis' complete range of products and solutions. (axis.com)
  • The course includes Academy training with lunches and coffee, all training material in an academy USB collateral, product brochures, a tool kit, a I/O demo tool and Axis Communications' Academy Diploma. (axis.com)
  • For Axis corporate rates, please refer to Axis Communications' Academy when you book your stay. (axis.com)
  • Blood Axis is a controversial music group founded by Michael Moynihan in 1989. (wikipedia.org)
  • Blood Axis have been depicted as fascists, and although their music is certainly a great deal more accomplished than than the usual heavy-metal/oi music popular in far-right circles, the iconography of his lyrics is influenced by north European mythology and many proto-Nazi philosophers. (wikipedia.org)
  • AXIS has completed 19 successful FDA inspections at our Hyderabad, India and Dilworth, MN sites for USFDA submission studies, including First-To-File and patient based clinical studies. (prweb.com)
  • AXIS Clinicals USA, a full-service Contract Research Organization (CRO), is joined by other global sites, AXIS Mexico (Est. (prweb.com)
  • Common causes of left axis deviation include an old or recent myocardial infarction, paced rhythms, emphysema, hyperkalemia, and right-sided accessory pathways, such as Wolff-Parkinson-White syndrome, among other causes, according to ECG Library. (reference.com)
  • by visiting the Axis Experience Center in our Chicago, Illinois office. (axis.com)
  • The Axis Experience Center-Chicago is located on the border of Rosemont & Chicago, Illinois. (axis.com)
  • So the said 3x3 sub-matrix gives the global space equivalents of the local co-ordinate axes. (gamedev.net)
  • cosmological sources do not correspond to the present state of the axis of the earth. (lulu.com)
  • The association of these objects with the axis of the earth does not appear to have been made explicitly and unambiguously before the 1st millennium BCE. (lulu.com)
  • This message is heard in virtually every ancient society on earth, but while this 'world axis' is familiar enough to scholars, little sense could be made of the stories. (lulu.com)
  • This colourful book is an edited slideshow intended as an accessible 'appetiser' for a forthcoming monograph about traditions of the world axis. (lulu.com)
  • This first volume provides an introduction to comparative mythology, catastrophism and the study of the mythical world axis as well as a new synopsis of the universal mythological substrate. (lulu.com)
  • It emerges that the mythical world axis cannot have been based on a single object seen or imagined at one of the poles, as has usually been supposed. (lulu.com)
  • The Hotel Planetstaden is located 5 minutes taxi drive from the Axis headquarter. (axis.com)
  • Located in Lapu-Lapu, Axis Pension Hotel is within a 10-minute drive of SM City Cebu and Ayala Center. (hipmunk.com)
  • Next week I promised to start going into more detail, when we start talking about early fly development and axis decisions. (scienceblogs.com)
  • 2004). AXIS USA offers the conveniences of a purpose-built 120,000 square foot facility to handle multiple studies at once, including an in-house Bioanalytical lab capable of handling over 15,000 samples per month, an on-site Dermatology Center, and a fully licensed Pharmacy. (prweb.com)
  • Since opening in 2014, AXIS USA has conducted around 100 studies and dosed over 5,000 volunteers at our Dilworth, MN site. (prweb.com)
  • It is suitable for AXIS M11 Network Camera Series. (cdw.com)
  • AXIS T93E05 Protective Housing is stripped down from the electronics components, maintaining the protection rating to defend AXIS M11 Network Camera Series. (cdw.com)
  • Interest in the field was sparked by a 2004 study showing that germ-free mice showed an exaggerated HPA axis response to stress compared to non-GF laboratory mice. (wikipedia.org)