Axinella
Porifera
Girolline, an antitumor compound isolated from a sponge, induces G2/M cell cycle arrest and accumulation of polyubiquitinated p53. (1/5)
Girolline, an antitumor compound isolated from a sponge, has been reported to inhibit the termination step of protein synthesis in vivo. In this study, we found that girolline induced G2/M cell cycle arrest in several tumor cell lines. Immunochemical analysis revealed that polyubiquitinated p53 was accumulated in girolline-treated cells, while other polyubiquitinated cellular proteins were not accumulated, indicating that the effect of girolline is specific for p53. On the other hand, girolline did not inhibit proteasome activity in vitro, and accumulation of polyubiquitinated p53 was scarcely detected in the presence of leptomycin B, an inhibitor of nuclear export. Based on the above findings, we propose that girolline affects the step of recruitment of polyubiquitinated p53 to the proteasome. (+info)Streptomyces axinellae sp. nov., isolated from the Mediterranean sponge Axinella polypoides (Porifera). (2/5)
(+info)Bromopyrrole alkaloids as lead compounds against protozoan parasites. (3/5)
(+info)New tetromycin derivatives with anti-trypanosomal and protease inhibitory activities. (4/5)
(+info)Further investigation of the Mediterranean sponge Axinella polypoides: isolation of a new cyclonucleoside and a new betaine. (5/5)
(+info)"Axinella" is a genus of demosponges, also known as marine sponges, that belong to the family Axinellidae. These sponges are commonly found in various parts of the world's oceans, particularly in tropical and temperate waters. They can be recognized by their characteristic skeletal structure, which is made up of spicules (small, needle-like structures) made of calcium carbonate or silica.
Axinella species are known for their ability to filter water and feed on plankton and other small particles. Some species have been found to contain bioactive compounds with potential medicinal applications, such as antimicrobial, anti-inflammatory, and anticancer properties. However, more research is needed to fully understand the potential benefits of these compounds and their safety for human use.
It's worth noting that "Axinella" is a scientific name used in taxonomy, which is the study of naming, classifying, and identifying organisms. It does not have a direct medical definition or application, but rather refers to a specific group of marine sponges with certain shared characteristics.
Porifera, also known as sponges, is a phylum of multicellular aquatic organisms characterized by having pores in their bodies. These pores allow water to circulate through the body, bringing in food and oxygen while expelling waste products. Sponges do not have true tissues or organs; instead, they are composed of specialized cells that perform specific functions. They are generally sessile (non-mobile) and live attached to rocks, coral reefs, or other underwater structures. Some species can be quite large, while others are microscopic in size. Sponges have a long fossil record dating back over 500 million years and play important roles in marine ecosystems as filter feeders and habitat providers for many other marine organisms.
Axinella
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Streptomyces axinellae
Krunoslav Babić
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Caballeraxine
Archaea
Cenarchaeum
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Oroidin
John Hooper (marine biologist)
Discovery and development of tubulin inhibitors
List of sponges of Ireland
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List of MeSH codes (B01)
Axinellidae
Henry John Carter
Axinella - Wikipedia
WoRMS - World Register of Marine Species - Axinella infundibuliformis (Linnaeus, 1759)
WoRMS - World Register of Marine Species - Axinella cannabina (Esper, 1794)
Description and molecular phylogeny of Axinella nayaritensis n. sp. (Porifera: Axinellida) from East Pacific and remarks about...
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African Register of Marine Species (AfReMaS) - Homaxinella arborescens (Ridley & Dendy, 1886)
African Register of Marine Species (AfReMaS)
MaNaPro 2019 - Navdeep Kaur poster presentation
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Sponges4
- Axinella is a genus of sponges in the family Axinellidae first described in 1862 by Eduard Oscar Schmidt. (wikipedia.org)
- Nuevas especies de esponjas encontradas en Cuba (new species of sponges from Cuba). (invemar.org.co)
- Axinellid cup sponges (Axinella infundibuliformis) are common on the bedrock and stony reef at depth ranges of 70m to over 100m. (jncc.gov.uk)
- Axinella polypoides, Dysidea avara, and Oscarella lobularis) were compared to those associated with the mesohyl of sponges and other animate or inanimate reference surfaces as well as with those from bulk seawater. (kit.edu)
Species1
- Species of Axinella occur in the Indian and Pacific Oceans. (wikipedia.org)
Infundibuliformis2
- The edge of the cup/fan is sharp, not neatly rounded as in Axinella infundibuliformis . (habitas.org.uk)
- Similar to Axinella infundibuliformis but often larger and more brittle, with a sharp edge to the cup (rounded in A. infundibuliformis ). (habitas.org.uk)
Corrugata1
- Axinella corrugata, Dragmacidon alvarezae, Dragmacidon reticulatum, Ptilocaulis walpersi, Myrmekioderma rea and one sponge belonging to the order Scopalinida: Scopalina ruetzleri were analyzed to assess their fatty acid composition in the phospholipid fraction. (usp.br)
Sponge2
- Axinella red tree sponge (Ptilocaulis sp. (saltyrevolution.co.uk)
- 2S*,5S*,6Z)-2,5-epoxydocosan-6-en-21-ynoic acid, new fatty acid from the marine sponge Haliclona fascigera Natural Products Chemistry & Research, 6(5), 19-22. (usp.br)
Source1
- additional source (of Axinella nanaspiculata Hartman, 1955 ) Green, G. (1977). (marinespecies.org)
Description3
- Description and molecular phylogeny of Axinella nayaritensis n. sp. (gbif.org)
- This dataset contains the digitized treatments in Plazi based on the original journal article Carballo, Jose Luis, Bautista-Guerrero, Eric, Cruz-Barraza, Jose Antonio (2018): Description and molecular phylogeny of Axinella nayaritensis n. sp. (gbif.org)
- original description (of Axinella nanaspiculata Hartman, 1955 ) Hartman, W.D. (1955). (marinespecies.org)
Genus1
- Axinella is a genus of sponges in the family Axinellidae first described in 1862 by Eduard Oscar Schmidt. (wikipedia.org)
Polypoides2
- The type species is Axinella polypoides. (nih.gov)
- La especie tipo es Axinella polypoides. (bvsalud.org)
Axinellidae1
- Género de ESPONJAS de la familia Axinellidae, que tienen un esqueleto coanosomático diferenciado en la región axial y extraaxial. (bvsalud.org)