Animal Rights
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Man-Machine Systems
Regulation of chamber-specific gene expression in the developing heart by Irx4. (1/1107)
The vertebrate heart consists of two types of chambers, the atria and the ventricles, which differ in their contractile and electrophysiological properties. Little is known of the molecular mechanisms by which these chambers are specified during embryogenesis. Here a chicken iroquois-related homeobox gene, Irx4, was identified that has a ventricle-restricted expression pattern at all stages of heart development. Irx4 protein was shown to regulate the chamber-specific expression of myosin isoforms by activating the expression of the ventricle myosin heavy chain-1 (VMHC1) and suppressing the expression of the atrial myosin heavy chain-1 (AMHC1) in the ventricles. Thus, Irx4 may play a critical role in establishing chamber-specific gene expression in the developing heart. (+info)MENT, a heterochromatin protein that mediates higher order chromatin folding, is a new serpin family member. (2/1107)
Terminal cell differentiation is correlated with the extensive sequestering of previously active genes into compact transcriptionally inert heterochromatin. In vertebrate blood cells, these changes can be traced to the accumulation of a developmentally regulated heterochromatin protein, MENT. Cryoelectron microscopy of chicken granulocyte chromatin, which is highly enriched with MENT, reveals exceptionally compact polynucleosomes, which maintain a level of higher order folding above that imposed by linker histones. The amino acid sequence of MENT reveals a close structural relationship with serpins, a large family of proteins known for their ability to undergo dramatic conformational transitions. Conservation of the "hinge region" consensus in MENT indicates that this ability is retained by the protein. MENT is distinguished from the other serpins by being a basic protein, containing several positively charged surface clusters, which are likely to be involved in ionic interactions with DNA. One of the positively charged domains bears a significant similarity to the chromatin binding region of nuclear lamina proteins and with the A.T-rich DNA-binding motif, which may account for the targeting of MENT to peripheral heterochromatin. MENT ectopically expressed in a mammalian cell line is transported into nuclei and is associated with intranuclear foci of condensed chromatin. (+info)Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. (3/1107)
Pitx1 is a Bicoid-related homeodomain factor that exhibits preferential expression in the hindlimb, as well as expression in the developing anterior pituitary gland and first branchial arch. Here, we report that Pitx1 gene-deleted mice exhibit striking abnormalities in morphogenesis and growth of the hindlimb, resulting in a limb that exhibits structural changes in tibia and fibula as well as patterning alterations in patella and proximal tarsus, to more closely resemble the corresponding forelimb structures. Deletion of the Pitx1 locus results in decreased distal expression of the hindlimb-specific marker, the T-box factor, Tbx4. On the basis of similar expression patterns in chick, targeted misexpression of chick Pitx1 in the developing wing bud causes the resulting limb to assume altered digit number and morphogenesis, with Tbx4 induction. We hypothesize that Pitx1 serves to critically modulate morphogenesis, growth, and potential patterning of a specific hindlimb region, serving as a component of the morphological and growth distinctions in forelimb and hindlimb identity. Pitx1 gene-deleted mice also exhibit reciprocal abnormalities of two ventral and one dorsal anterior pituitary cell types, presumably on the basis of its synergistic functions with other transcription factors, and defects in the derivatives of the first branchial arch, including cleft palate, suggesting a proliferative defect in these organs analogous to that observed in the hindlimb. (+info)Dynamic expression of lunatic fringe suggests a link between notch signaling and an autonomous cellular oscillator driving somite segmentation. (4/1107)
The metameric organization of the vertebrate trunk is a characteristic feature of all members of this phylum. The origin of this metamerism can be traced to the division of paraxial mesoderm into individual units, termed somites, during embryonic development. Despite the identification of somites as the first overt sign of segmentation in vertebrates well over 100 years ago, the mechanism(s) underlying somite formation remain poorly understood. Recently, however, several genes have been identified which play prominent roles in orchestrating segmentation, including the novel secreted factor lunatic fringe. To gain further insight into the mechanism by which lunatic fringe controls somite development, we have conducted a thorough analysis of lunatic fringe expression in the unsegmented paraxial mesoderm of chick embryos. Here we report that lunatic fringe is expressed predominantly in somite -II, where somite I corresponds to the most recently formed somite and somite -I corresponds to the group of cells which will form the next somite. In addition, we show that lunatic fringe is expressed in a highly dynamic manner in the chick segmental plate prior to somite formation and that lunatic fringe expression cycles autonomously with a periodicity of somite formation. Moreover, the murine ortholog of lunatic fringe undergoes a similar cycling expression pattern in the presomitic mesoderm of somite stage mouse embryos. The demonstration of a dynamic periodic expression pattern suggests that lunatic fringe may function to integrate notch signaling to a cellular oscillator controlling somite segmentation. (+info)Characterization of prethymic progenitors within the chicken embryo. (5/1107)
The thymic primordium in both birds and mammals is first colonized by cells emerging from the intra-embryonic mesenchyme but the nature of these precursors is poorly understood. We demonstrate here an early embryonic day 7 prethymic population with T lymphoid potential. Our work is a phenotypic analysis of, to date, the earliest embryonic prethymic progenitors arising in the avian para-aortic area during ontogeny. The phenotype of these cells, expressing the cell surface molecules alpha2beta1 integrin, c-kit, thrombomucin/MEP21, HEMCAM and chL12, reflects functional properties required for cell adhesion, migration and growth factor responsiveness. Importantly, the presence of these antigens was found to correlate with the recolonization of the recipient thymus following intrathymic cell transfers. These intra-embryonic cells were also found to express the Ikaros transcription factor, the molecular function of which is considered to be prerequisite for embryonic lymphoid development. (+info)Expression of Zkrml2, a homologue of the Krml1/val segmentation gene, during embryonic patterning of the zebrafish (Danio rerio). (6/1107)
We have identified Zkrml2, a novel homologue of the segmentation gene Krml/val in zebrafish (Danio rerio). Zkrml2 shows 72% and 92% identity in its basic leucine zipper domain with mouse Krml1 and zebrafish val, respectively. Zkrml2 is expressed coincident with MyoD throughout the somites starting at the three somite stage, becomes restricted to the dermomyotome, and subsequently disappears. Transient expression is also detected in the reticulospinal and oculomotor neurons. Zkrml2 maps to the Oregon linkage group 11 (Boston Linkage group 14) with no mapped zebrafish mutations nearby. (+info)Role of Pitx1 upstream of Tbx4 in specification of hindlimb identity. (7/1107)
In spite of recent breakthroughs in understanding limb patterning, the genetic factors determining the differences between the forelimb and the hindlimb have not been understood. The genes Pitx1 and Tbx4 encode transcription factors that are expressed throughout the developing hindlimb but not forelimb buds. Misexpression of Pitx1 in the chick wing bud induced distal expression of Tbx4, as well as HoxC10 and HoxC11, which are normally restricted to hindlimb expression domains. Wing buds in which Pitx1 was misexpressed developed into limbs with some morphological characteristics of hindlimbs: the flexure was altered to that normally observed in legs, the digits were more toe-like in their relative size and shape, and the muscle pattern was transformed to that of a leg. (+info)Production and characterization of a soluble, active form of Tva, the subgroup A avian sarcoma and leukosis virus receptor. (8/1107)
The receptor for the subgroup A avian sarcoma and leukosis viruses [ASLV(A)] is the cellular glycoprotein Tva. A soluble form of Tva, sTva, was produced and purified with a baculovirus expression system. Using this system, 7 to 10 mg of purified sTva per liter of cultured Sf9 cells was obtained. Characterization of the carbohydrate modification of sTva revealed that the three N glycosylation sites in sTva were differentially utilized; however, the O glycosylation common to Tva produced in mammalian and avian cells was not observed. Purified sTva demonstrates significant biological activity, specifically blocking infection of avian cells by ASLV(A) with a 90% inhibitory concentration of approximately 25 pM. A quantitative enzyme-linked immunosorbent assay, developed to assess the binding of sTva to ASLV envelope glycoprotein, demonstrates that sTva has a high affinity for EnvA, with an apparent dissociation constant of approximately 0.3 nM. Once they are bound, a very stable complex is formed between EnvA and sTva, with an estimated complex half-life of 6 h. The soluble receptor protein described here represents a valuable tool for analysis of the receptor-envelope glycoprotein interaction and for structural analysis of Tva. (+info)Avian proteins are proteins derived from birds that may have potential medical applications, such as in the development of vaccines or therapeutic drugs.
Avian proteins refer to proteins that are derived from birds. In the medical field, avian proteins are often used as a source of therapeutic agents, such as antibodies and growth factors, for the treatment of various diseases. For example, chicken egg white lysozyme is used as an antibiotic in ophthalmology, and chicken serum albumin is used as a plasma expander in surgery. Additionally, avian proteins are also used in the development of vaccines and diagnostic tests.
Feed ban
... and avian) proteins.[citation needed] In July 2003 Will Hueston, who was then the director of the University of Minnesota ... The term Feed ban is usually a reference to the regulations that have prohibited the feeding of most mammalian-derived proteins ...
Glossary of bird terms
ISBN 978-0-643-10293-4. Klasing, Kirk C. (1999). "Avian gastrointestinal anatomy and physiology". Seminars in Avian and Exotic ... It is extremely high in protein and fat, containing higher levels than cow or human milk and has been shown to also contain ... ISBN 978-1-60342-561-2. Lucas, Alfred M. (1972). Avian Anatomy - integument. East Lansing, Michigan: USDA Avian Anatomy Project ... In Avian Flight (2005), the author notes that "most birds open and close their wings during every wing beat cycle", and ...
Eggshell
Romanoff, A.L., A.J. Romanoff (1949) The avian egg. New York, Wiley. Burley, R.W., D.V. Vadehra (1989) The Avian Egg: Chemistry ... These proteins affect crystallization, which in turn affects the eggshell structure. The concentration of eggshell proteins ... Without the protein, the crystal structure would be too brittle to keep its form and the organic matrix is thought to have a ... While the bulk of eggshell is made of calcium carbonate, it is now thought that the protein matrix has an important role to ...
Coraciidae
Sibley, Charles G (1960). "The electrophoretic patterns of avian egg-white proteins as taxonomic characters". Ibis. 102 (2): ... Bock, Walter J. (1994). History and Nomenclature of Avian Family-Group Names. Bulletin of the American Museum of Natural ...
Bird fancier's lung
Avian proteins include mucins and antibodies, which stimulate a significant immune response from the body. The lungs become ... BFL is diagnosed based on symptoms, and how these get worse on exposure to avian proteins. Radiology can show damage to the ... However, corticosteroids tend not to have a long-term effect if avian protein is not also removed from the environment. Dosage ... Symptoms worsen upon skin exposure to avian proteins in 85% of patients. Symptoms tend to occur or worsen within 4-8 hours ...
Intrastructural help
"Localization of a T-cell epitope within the nucleocapsid protein of avian coronavirus". Immunology. 74 (1): 8-13. ISSN 0019- ... These particles contain Gag protein and HIV-Env surface protein. These particles can be recognized by B cells and subsequently ... Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV ...
Glucokinase regulatory protein
Polakof S, Míguez JM, Soengas JL (July 2009). "A hepatic protein modulates glucokinase activity in fish and avian liver: a ... The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in ... CS1: long volume value, Protein pages needing a picture, Genes on human chromosome 2, Proteins). ... GKRP is a 68 kD protein of 626 amino acids. It is coded for by a 19 exon gene, GCKR, on the short arm of chromosome 2 (2p23). ...
FKBP5
Smith DF, Albers MW, Schreiber SL, Leach KL, Deibel MR (November 1993). "FKBP54, a novel FK506-binding protein in avian ... FK506 binding protein 5, also known as FKBP5, is a protein which in humans is encoded by the FKBP5 gene. The protein encoded by ... March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human ... along with the 90 kDa heat shock protein and PTGES3 (P23 protein). As an Hsp90-associated co-chaperone that regulates the ...
Anticancer gene
Apoptin: Apoptin, a protein produced from avian viruses, causes p53-deficient tumor-specific apoptosis manner. After attaching ... This protein binds to anti-apoptotic proteins resulting in these proteins' inhibition. As a p53 inducible gene, NOXA is ... NS1 is considered a regulatory protein due to its activity in transcription, translation, and protein-protein interactions, ... This protein, also known as viral protein 3 (VP3) was isolated from chickens, and has been shown to cause PCD in transformed ...
Plant defense against herbivory
Witmer, M.C. (1998). "Ecological and evolutionary implications of energy and protein requirements of avian frugivores eating ... The bacterium produces proteins that, when ingested, kill lepidopteran caterpillars. The gene encoding for these highly toxic ... Certain alkaloids bind to nucleic acids and can inhibit synthesis of proteins and affect DNA repair mechanisms. Alkaloids can ... Finally, some plants can also produce plant defensive proteins, which upon ingestion, end up poisoning the herbivore. Plants ...
Vaccine resistance
"Avian metapneumovirus (AMPV) attachment protein involvement in probable virus evolution concurrent with mass live vaccine ... "Avian metapneumovirus SH gene end and G protein mutations influence the level of protection of live-vaccine candidates". ... Berg, Thierry P. Van Den (2000-06-01). "Acute infectious bursal disease in poultry: A review". Avian Pathology. 29 (3): 175-194 ... Witter, R. L. (1997). "Increased Virulence of Marek's Disease Virus Field Isolates". Avian Diseases. 41 (1): 149-163. doi: ...
Telomeric repeat-binding factor 2
This region gets its name from a viral protein called Myb derived from the avian myeloblastosis virus. Specifically, the ... There are 4 domain categories on the TERF2 protein that allow it to bind to both other proteins in the shelterin protein ... TERF2 is also known to recruit certain client proteins, also known as accessory factors. These client proteins are often ... Two other domains also work to bind and influence the activity of proteins associated with the TERF2 protein. Both are unique ...
Lck
"Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein". Cell. 15 ... Lymphoid protein tyrosine phosphatase (lyp), is one of the suppressor of lck activity and mutations in this protein are ... Lck (or lymphocyte-specific protein tyrosine kinase) is a 56 kDa protein that is found inside specialized cells of the immune ... "Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase". The ...
Ovomucin
v t e (Protein pages needing a picture, Eggs, Mucins, Avian proteins, All stub articles, Biochemistry stubs). ... The protein makes up around 2-4% of the protein content of egg whites; like other members of the mucin protein family, ovomucin ...
Beta-keratin
"Beta-keratins of differentiating epidermis of snake comprise glycine-proline-serine-rich proteins with an avian-like gene ... The hydrogen on the amide of one protein chain is hydrogen bonded to the amide oxygen of the neighboring protein chain. The ... In this structure, individual protein chains are aligned side-by-side with every other protein chain aligned in an opposite ... "corneous beta-proteins" or "keratin-associated beta-proteins." β-keratins add much more rigidity to reptilian skin than alpha- ...
HSP90B1
... properties and homology with mammalian and avian stress proteins". Biochemistry. 29 (21): 5138-44. doi:10.1021/bi00473a020. ... Heat shock protein 90kDa beta member 1 (HSP90B1), known also as endoplasmin, gp96, grp94, or ERp99, is a chaperone protein that ... GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma Bloch O, Crane CA, ... Li Z, Dai J, Zheng H, Liu B, Caudill M (March 2002). "An integrated view of the roles and mechanisms of heat shock protein gp96 ...
Common raven physiology
Glucose, calcium and proteins are other components of avian blood's chemical properties. Blood glucose levels range from 200 to ... "Avian thermoregulation in the heat: Phylogenetic variation among avian orders in evaporative cooling capacity and heat ... Avian kidneys do not send urine to a bladder. Instead it is sent via the ureters to the cloaca to be deposited into the lower ... Avian blood possesses a more alkaline pH ranging from 7.5 to 7.6, and blood bicarbonate values are between 16 and 32 mmol/L. In ...
Domestic pigeon
A form of hypersensitivity pneumonitis, pigeon lung is caused by the inhalation of the avian proteins found in feathers and ... Journal of Avian Medicine and Surgery. Association of Avian Veterinarians. 23 (1): 1-5. doi:10.1647/2007-049R.1. JSTOR 27670700 ... Pigeon meat, both from squabs and from adult birds, are still a source of protein for people worldwide. Breeds of pigeons ... Hagstrum, Jonathan T. (September 2001). "Infrasound and the Avian Navigational Map". Journal of Navigation. 54 (3): 377-391. ...
National Centre for Foreign Animal Disease
The lab has diagnostic capabilities for a large number of FADs including, but not limited to: avian influenza, foot-and-mouth ... These services involve the production and characterization of: 1) monoclonal antibodies 2) recombinant proteins and 3) ... In addition to OIE Reference Laboratory status for classical swine fever and avian influenza, this Section is also the National ... This unit is involved in assays for the determination of pathogenicity indices for avian viruses, the production of serum ...
MYB (gene)
"Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by ... Myb proto-oncogene protein is a member of the MYB (myeloblastosis) family of transcription factors. The protein contains three ... MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain. Plants contain a MYB-protein ... "Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role ...
CDKN2C
... a component of the lamin B receptor complex and a new integral membrane protein of the avian erythrocyte nuclear envelope". J. ... The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ... Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. CDKN2C has ...
Spanish flu research
In avian virus the HA protein preferentially binds to alpha-2,3 sialic acid, which is the major form in the avian enteric tract ... Kou Z, Lei FM, Yu J, Fan ZJ, Yin ZH, Jia CX, Xiong KJ, Sun YH, Zhang XW, Wu XM, Gao XB, Li TX (2005). "New genotype of avian ... Such mutations in avian H5N1 viruses can change virus strains from being inefficient at infecting human cells to being as ... Altogether, only a handful of mutations may need to take place in order for H5N1 avian flu to become a pandemic virus like the ...
NEO1
Vielmetter J, Kayyem JF, Roman JM, Dreyer WJ (1995). "Neogenin, an avian cell surface protein expressed during terminal ... Neogenin is a protein that in humans is encoded by the NEO1 gene. NEO1 has been shown to interact with PTK2. Also Neogenin ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 15, Human proteins, All ... a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3-q23". Genomics. 41 (3): 414-21. doi: ...
Env (gene)
The Env proteins of the Avian Sarcoma and Leukosis virus (ASLV) and the Murine Leukemia Virus (MLV) are both trimers of SU-TM ... the surface protein (SU) and the transmembrane protein (TM). The tropism of the virus is determined by the SU protein domain ... The protein is called syncytin in mammals. Viral structural protein Gene+Products,+env at the U.S. National Library of Medicine ... This precursor is cleaved by host cell enzymes to yield the surface protein subunit, gp85, and the transmembrane protein ...
Vitellin
Avian proteins, Phosphoproteins, All stub articles, Protein stubs). ... Vitellin is a protein found in the egg yolk. It is a phosphoprotein. Vitellin is a generic name for major of many yolk proteins ... Vitellin is an umbrella term for many vitellin sub proteins and some of these sub proteins are linked with egg allergies. Egg ... "Characterization of vitellin, egg-specific protein and 30 kDa protein from Bombyx eggs, and their fates during oogenesis and ...
Teratohyla midas
The avian species would capture the frog in its bill, and glass frogs would serve as a source of protein for tropical avians. T ... The twenty-five frogs were then observed based on four different visual models: tetrachromatic avian, trichromatic snake, ... Predators of glass frogs are avian species and other reptilian species. Recorded cases of crested quetzal preying on glass ...
SKI protein
Specifically, avian fibroblasts depend on the SKI protein as a transcription co-regulator inducing transformation. The ... The SKI protein and the CPB protein compete for binding with the Smad proteins, specifically competing with the Smad-3 and CReB ... The SnoN protein was identified as a similar protein and is often discussed in conjugation with the Ski protein in publications ... TGF- β is a protein which regulates cell growth. Signaling is regulated by a family of proteins called the Smad proteins. SKI ...
Avian adenovirus
The genome codes for 40 proteins. Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral ... Avian Adenoviruses, reviewed and published by WikiVet at http://en.wikivet.net/Avian_Adenoviruses, accessed 18/08/2011. ... Avian adenoviruses have a worldwide distribution and it is common to find multiple species on a single farm. The most common ...
Fungal immunomodulatory protein
Avian Pathology. 42 (3): 235-247. doi:10.1080/03079457.2013.780121. PMID 23627727. S2CID 24714876. Lin WH, Hung CH, Hsu CI, Lin ... Protein Data Bank Accession number 3KCW_A) from G. microsporum FIP-tve (NCBI DNA Accession number XM_008037967; Protein ... Hsu HC, Hsu CI, Lin RH, Kao CL, Lin JY (April 1997). "Fip-vvo, a new fungal immunomodulatory protein isolated from Volvariella ... Fungal immunomodulatory proteins (FIPs) are a type of functional compound (other compounds include polysaccharides and ...
Ovomucoid
Protein pages needing a picture, Protease inhibitors, Avian proteins, All stub articles, Protein stubs). ... Ovomucoid is a protein found in egg whites. It is a trypsin inhibitor with three protein domains of the Kazal domain family. ... "Structure and energetics of protein-protein interactions: the role of conformational heterogeneity in OMTKY3 binding to serine ... It is the protein most often causing egg allergy. At least four IgE epitopes have been identified. Three other egg white ...
Pathology of Hypersensitivity Pneumonitis: Definition, Epidemiology, Etiology
Classification of Avian Anemia and Interpretation of Avian Protein Fractions - Clinical Avian Pathology Services
how the avian patient responds to anemia and the effects of anemia on red blood cell morphology. In addition, the avian protein ... Classification of Avian Anemia and Interpretation of Avian Protein Fractions. Module 3 provides classification and etiologies ... Providing the highest quality of education in hematology and clinical pathology for avian and reptiles. Contact Me ...
Structures of influenza A virus RNA polymerase offer insight into viral genome replication | Nature
Structures of RNA polymerase of human and avian influenza A viruses reveal that the interface of the RNA polymerase dimer ... and avian influenza A/duck/Fujian/01/2002 (H5N1) viruses at a resolution of 3.0-4.3 Å, in the presence or absence of ... there are no complete structures available for human and avian FluPolA. Furthermore, the molecular mechanisms of genomic viral ... Mutations in the PA protein of avian H5N1 influenza viruses affect polymerase activity and mouse virulence. J. Virol. 92, ...
Orthovisc, Synvisc (hyaluronic-acid-and-derivatives) dosing, indications, interactions, adverse effects, and more
Questions and Answers | Pandemic Influenza (Flu) | CDC
... a new influenza A virus with a hemagglutinin protein or both a hemagglutinin protein and a neuraminidase protein from an avian ... and avian influenza A (H7N9) viruses. These two different avian influenza A viruses have caused sporadic human infections, some ... Any novel influenza A virus, such as those of avian or swine origin, has the potential to cause an influenza pandemic. Some ... Influenza A viruses are divided into subtypes based on two proteins on the surface of the virus: the hemagglutinin (H) and the ...
Publication : USDA ARS
The HA protein revealed a Q226L mutation when compared with the putative parental avian HA protein, indicating a preferential ... Pigs have been suggested to be the mixing vessel for avian and human influenza viruses because the porcine trachea contains ... Molecular and phylogenetic analyses of these viruses revealed that the HA segment is similar to an avian influenza virus (AIV) ... In the pig, genetic reassortment to create novel influenza subtypes by mixing avian, human and swine influenza viruses is ...
New biological route for swine flu to human infections - ScienceBlog.com
Earlier work by Doudna and Mehle with avian influenza had shown that a mutation in the viral protein PB2 - whereby glutamic ... they introduced the mutation into the PB2 protein of the avian influenza. As with swine influenza, the polymerase activity and ... In their investigation, Mehle and Doudna found that the 2009 H1N1 virus has acquired the SR polymorphism in its PB2 protein ... The influenza polymerase consists of three proteins dubbed PB1, PB2 and PA, that work with viral RNA and nucleoprotein to ...
SMART: LIM domain annotation
Mammalian and avian cysteine-rich protein (CRP), a 192 amino-acid protein of unknown function. Seems to interact with zyxin. ... LIM kinases and other proteins. LIM domains are protein-protein interaction motifs, can inhibit binding of LIM-HD proteins to ... LIM domains mediate protein-protein interactions and, within LIM-homeodomain proteins, act as negative regulators of the ... alpha-actinin and the cysteine-rich protein (CRP), to examine the involvement of LIM domains in protein-protein interactions. ...
NIOSHTIC-2 Search Results - Full View
Search Results | AVMA
Avian veterinarians should cautiously interpret results from plasma EPH assays for these protein fractions. (Am J Vet Res 2005; ... and γ-globulin concentrations may not be a reliable tool for assessing avian health. Small amounts of these proteins in birds ... To determine the reliability (agreement between duplicate samples) of total protein, albumin, prealbumin, α1-, α2-, β-, and γ- ... Objective-To determine agreement for total protein (TP) and albumin concentrations measured by a point-of-care biochemical ...
GPR74/NPFFR2 Proteins: Novus Biologicals
Browse our GPR74/NPFFR2 Protein catalog backed by our Guarantee+. ... Avian. Ll. =. Llama. Bb. =. Baboon. Ma. =. Mammal. Ba. =. ... GPR74/NPFFR2 protein, NPFFR2 protein, G-protein coupled receptor 74 protein, GPR74G protein-coupled receptor 74 protein, ... neuropeptide FF 2 protein, neuropeptide FF receptor 2 protein, Neuropeptide G-protein coupled receptor protein, NPFF2G-protein ... GPR74/NPFFR2 Proteins. We offer GPR74/NPFFR2 Peptides and GPR74/NPFFR2 Proteins for use in common research applications: ...
The 5 Best Pigeon Wormers - NE Pigeon Supplies
Frontiers | Poultry Response to Heat Stress: Its Physiological, Metabolic, and Genetic Implications on Meat Production and...
... and heat-shock proteins. The focus of this article is in 3-fold: (1) to identify the mechanism of heat stress that causes meat ... and heat-shock proteins. The focus of this article is in threefold: (1) to identify the mechanism of heat stress that causes ... HS causes poor meat quality by impairing protein synthesis and augmenting undesirable fat in meat. Studies previously conducted ... HS causes poor meat quality by impairing protein synthesis and augmenting undesirable fat in meat. Studies previously conducted ...
Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015 | Scientific Reports
The causative agent behind this outbreak was identified as H5N1 highly pathogenic avian influenza virus (HPAIV). Genetic and ... Phylogenetics of varied subtypes of avian influenza viruses in China: potential threat to humans. Protein Cell 5, 253-257 (2014 ... even though they possess the avian adaptation residues with Q591, E627 and D701 on the PB2 protein. ... How to cite this article: Bi, Y. et al. Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015 ...
PRIME PubMed | A pseudotype baculovirus-mediated vaccine confers protective immunity against lethal challenge with H5N1 avian...
A pseudotype baculovirus-mediated vaccine confers protective immunity against lethal challenge with H5N1 avian influenza virus ... protein of highly pathogenic H5N1 avian influenza virus, A/Chicken/Hubei/327/2004 (HB/327). The resultant recombinant ... protein of highly pathogenic H5N1 avian influenza virus, A/Chicken/Hubei/327/2004 (HB/327). The resultant recombinant ... Enhanced protective efficacy of H5 subtype avian influenza DNA vaccine with codon optimized HA gene in a pCAGGS plasmid vector. ...
Cofilin Polyclonal Antibody (10960-1-AP)
Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus ... Cofilin Fusion Protein Ag1399 (1-166 aa encoded by BC012318) View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;} ... protein phosphorylation protein import into nucleus actin filament organization establishment of cell polarity cell projection ... Protein Aliases: 18 kDa phosphoprotein; CFL-1; COF1; cofilin 1 (non-muscle); Cofilin, non-muscle isoform; Cofilin-1; Cofilin1; ...
Related GMR Articles | Page 4 | GMR | Genetics and Molecular Research | The Original by FUNPEC-RP
Animals; Avian Proteins; Chickens; Female; Genetic association studies; Genotype; Insulin-like growth factor I; Phenotype; ... Plant Proteins; Proteome; Sapindaceae; seeds Paullinia cupana Kunth var. sorbilis (Mart.) Ducke, the cultivated guarana plant, ... Plant Proteins; seeds; Strobilurins; Triazoles; Zea mays ... Proteins ... more A.L. Souza; J.L. Lopez-Losano; P.C.S. Angelo ...
Pesquisa | Portal Regional da BVS
We have analyzed protein-coding sequence divergence among avian species. The intracellular tyrosine kinase domain of CSF1R was ... The contact amino acids in both CSF1 and CSF1R diverged among avian species. Ligand-binding domain swaps between chicken and ... The rapid evolution in the extracellular domain of avian CSF1R suggests that at least in birds this ligand-receptor interaction ... we identified amino acids involved in avian receptor-ligand interactions. ...
Angelito Inocencio Nepomuceno - Citation Index - NCSU Libraries
MeSH headings : Animals; Avian Proteins / analysis; Avian Proteins / chemistry; Chickens; Chromatography, Liquid; Female; Laser ... Plant Proteins / analysis; Plant Proteins / chemistry; Plant Proteins / immunology; Proteomics; Seeds / chemistry; Seeds / ... Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Proteolysis; Ubiquitin-Protein Ligases / genetics; Ubiquitin- ... MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / genetics; CCAAT-Enhancer-Binding Protein-alpha / metabolism; ...
WHO EMRO | Pandemic influenza | Programmes | Egypt
Avian influenza, commonly called bird flu, is an infectious viral disease of birds. Not all avian influenza viruses infect ... and primarily avian influenza, is a serious concern for Egypt. ... large dependence on poultry as the main form of animal protein ... Avian influenza, commonly called bird flu, is an infectious viral disease of birds. Not all avian influenza viruses infect ... WHO and FAO have established a platform for joint risk assessment on avian influenza where both epidemiological and virological ...
CDC-Authored Genomics and Precision Health Publications Database|Home|PHGKB
The molecular characterizations of surface proteins hemagglutinin and neuraminidase from recent H5Nx avian influenza viruses. ... Highly Pathogenic Avian Influenza A(H5N1) Viruses at the Animal-Human Interface in Vietnam, 2003-2010. Creanga Adrian, Hang ... Antiviral susceptibility of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses isolated from birds and mammals in ... Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins. Gubareva Larisa V ...
WikiGenes - fabZ - (3R)-hydroxymyristol acyl carrier protein...
Avian Dis. (2006) [Pubmed] ... wikigene or wiki gene protein drug chemical gene disease author ... Modulations in lipid A and phospholipid biosynthesis pathways influence outer membrane protein assembly in Escherichia coli K- ... tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs ...
DeCS
The name derives from viral oncogene-derived protein oncogene protein v-ets of the AVIAN ERYTHROBLASTOSIS VIRUS. ... c ets Protein c ets Proto Oncogene Protein c ets Proto Oncogene Proteins c-ets Protein c-ets Proto-Oncogene Protein c-ets Proto ... c ets Protein. c ets Proto Oncogene Protein. c ets Proto Oncogene Proteins. c-ets Protein. c-ets Proto-Oncogene Protein. c-ets ... Protein, c-ets Proto-Oncogene Protein, ets Proto-Oncogene Proto Oncogene Protein ets Proto Oncogene Proteins c ets Proto- ...
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Eggs as Functional Foods and Nutraceuticals for Human Health | Books Gateway | Royal Society of Chemistry
Open the PDF Link PDF for CHAPTER 12: Innate Antimicrobial Proteins and Peptides of Avian Egg in another window ... Open the PDF Link PDF for CHAPTER 17: Advances in the Separation of Functional Egg Proteins - Egg White Proteins in another ... Open the PDF Link PDF for CHAPTER 18: Advances in the Separation of Functional Egg Proteins - Egg Yolk Proteins in another ... CHAPTER 12: Innate Antimicrobial Proteins and Peptides of Avian Egg p211-222 ...
Avian flu pandemic - SourceWatch
New research shows that this bird flu currently lacks the protein key to unlock certain cells in the human upper respiratory ... Avian Influenza, CIDRAP website.. *H5N1 and "Avian influenza" in the Wikipedia (also posted on "Avian Bird Flu Information Zone ... UN report: avian flu & factory farms. According to a United Nations (UN) report, avian flu can be traced to filthy, crowded, ... Avian influenza, World Health Organization website: Avian influenza - fact sheet, February 15, 2004, and "Geographical spread ...
H5N1HemagglutininViralVirusesNeuraminidase proteinsSubtypesPeptidesGenesPandemicChickensH7N9BirdsInfectionKinasesInfectiousInfect humansVirusHumansClinicalReceptorAntiviralGeneticAmino acidPoultryHaemagglutininLipidMammalianHuman casesTranscriptionInsulinNormalCommonSurfaceMeatFunctionShownAnalysisRiskActivity
H5N112
- Avian influenza H5N1 has shown high mortality rate in human. (tokushima-u.ac.jp)
- Non-structural protein 1 (NS1) is a virulence factor of H5N1. (tokushima-u.ac.jp)
- Here, using crystallography and cryo-electron microscopy, we determine the structures of FluPol A from human influenza A/NT/60/1968 (H3N2) and avian influenza A/duck/Fujian/01/2002 (H5N1) viruses at a resolution of 3.0-4.3 Å, in the presence or absence of a cRNA or vRNA template. (nature.com)
- Fig. 1: Structures of human H3N2 and avian H5N1 FluPol A . (nature.com)
- The causative agent behind this outbreak was identified as H5N1 highly pathogenic avian influenza virus (HPAIV). (nature.com)
- The Qinghai-like Clade 2.2 virus was found to possess a high genetic relationship with viruses isolated from other countries on the migratory flyway of wild birds 4 , suggesting that the migration of wild birds played an important role in circulating H5N1 HPAIV viruses between the different avian populations. (nature.com)
- 2. With the confirmation of avian influenza in some countries of the African Region early this year, the risk of human infection due to the highly pathogenic avian influenza virus H5N1 will persist, as will the threats of occurrence of an influenza pandemic. (who.int)
- In this study, baculovirus pseudotyped with vesicular stomatitis virus glycoprotein was used as a vector to express the hemagglutinin (HA) protein of highly pathogenic H5N1 avian influenza virus, A/Chicken/Hubei/327/2004 (HB/327). (unboundmedicine.com)
- Highly Pathogenic Avian Influenza A(H5N1) Viruses at the Animal-Human Interface in Vietnam, 2003-2010. (cdc.gov)
- Since the first confirmed human infection with avian influenza A(H5N1) virus was reported in Hong Kong Special Administrative Region in 1997, sporadic zoonotic avian influenza viruses causing illness in humans have been identified globally, with the WHO Western Pacific Region as one of the hotspots. (who.int)
- From November 2003, when a resurgence of H5N1 virus activity in humans and animals occurred, through September 2017, 1,838 human infections with avian influenza viruses in the region were reported to WHO. (who.int)
- Update: isolation of avian influenza A(H5N1) viruses from humans--Hong Kong, 1997-1998. (who.int)
Hemagglutinin4
- Influenza A viruses are divided into subtypes based on two proteins on the surface of the virus: the hemagglutinin (H) and the neuraminidase (N). There are 18 different hemagglutinin subtypes and 11 different neuraminidase subtypes (H1 through H18 and N1 through N11). (cdc.gov)
- For example, an exchange of genes between a human influenza A virus and an avian influenza A virus can create a new influenza A virus with a hemagglutinin protein or both a hemagglutinin protein and a neuraminidase protein from an avian influenza A virus. (cdc.gov)
- Avian influenza viral nucleocapsid and hemagglutinin proteins induce chicken CD8 + memory T lymphocytes. (southernbiotech.com)
- The molecular characterizations of surface proteins hemagglutinin and neuraminidase from recent H5Nx avian influenza viruses. (cdc.gov)
Viral8
- When a host is infected with an influenza virus, the polymerase enables the virus to multiply in the host's cells by making copies of the viral genome and directing production of its proteins. (scienceblog.com)
- The influenza polymerase consists of three proteins dubbed PB1, PB2 and PA, that work with viral RNA and nucleoprotein to transcribe and replicate the influenza genome in a host cell. (scienceblog.com)
- Earlier work by Doudna and Mehle with avian influenza had shown that a mutation in the viral protein PB2 - whereby glutamic acid is replaced at a certain position on the amino acid chain with lysine - enables the virus to jump from birds to humans. (scienceblog.com)
- As with swine influenza, the polymerase activity and viral replication of the avian virus became enhanced in humans. (scienceblog.com)
- The A56 protein is capable of binding two viral proteins, a serine protease inhibitor (K2) and the vaccinia virus complement control protein (VCP), and anchoring them to the surface of infected cells. (microbiologyresearch.org)
- The name derives from viral oncogene-derived protein oncogene protein v-ets of the AVIAN ERYTHROBLASTOSIS VIRUS. (bvsalud.org)
- Avian influenza, commonly called bird flu, is an infectious viral disease of birds. (who.int)
- Overview of Viral Infections A virus is composed of nucleic acid, either DNA or RNA, surrounded by a protein coat. (msdmanuals.com)
Viruses12
- Antigenic shift also can happen when a non-human influenza A virus (for example an avian influenza virus) exchanges genetic information with other influenza A viruses in a process called genetic reassortment, and the resultant new virus is able to infect people. (cdc.gov)
- The federal government has created a stockpile of some vaccines against select influenza A viruses with pandemic potential that could be used in the event of a pandemic, including vaccines against certain avian influenza A (e.g. (cdc.gov)
- Pigs have been suggested to be the mixing vessel for avian and human influenza viruses because the porcine trachea contains binding receptors with preferences for human and avian influenza viruses. (usda.gov)
- In the pig, genetic reassortment to create novel influenza subtypes by mixing avian, human and swine influenza viruses is possible. (usda.gov)
- Molecular and phylogenetic analyses of these viruses revealed that the HA segment is similar to an avian influenza virus (AIV) H2N3 isolated from mallards and the NA sequence is similar to an AIV H4N3 isolated from blue-winged teal. (usda.gov)
- Here we characterize genetically similar reassortant H2N3 viruses isolated from pigs from two farms in the U.S. Molecular and phylogenetic analysis revealed that the HA, NA, and PA gene segments are similar to those of avian influenza viruses of the American lineage, whereas other segments are similar to those of contemporary swine influenza viruses. (usda.gov)
- In addition, since the gene encoding the A56 protein is non-essential, it can be used as an insertion point for foreign genes and has been deleted in some viruses that are in clinical development as oncolytic agents. (microbiologyresearch.org)
- Sometimes cats can get infected with avian viruses because they're eating infected bird meat, where they might be exposed to feces or even water that might be contaminated with feces from birds. (cdc.gov)
- But in the United States, and especially in the Northeastern United States, back in the late 1990s and early 2000s, there were quite a bit of these avian influenza viruses, known as the H7N2 subtype. (cdc.gov)
- Horimoto T, Kawaoka Y. Pandemic threat posed by avian influenza A viruses. (who.int)
- 1. What is the likelihood that additional human cases of infection with avian influenza A(H5) viruses will occur? (who.int)
- 2. What is the likelihood of human-to-human transmission of avian influenza A(H5) viruses? (who.int)
Neuraminidase proteins2
- Theoretically, any combination of the 18 hemagglutinins and 11 neuraminidase proteins are possible, but not all have been found in animals and even fewer have been found to infect humans. (cdc.gov)
- Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins. (cdc.gov)
Subtypes1
- Regional analyses of human infections with avian influenza subtypes revealed distinct patterns and variations in epidemiology across countries, age, and time. (who.int)
Peptides4
- We offer GPR74/NPFFR2 Peptides and GPR74/NPFFR2 Proteins for use in common research applications: Blocking/Neutralizing, Control. (novusbio.com)
- Our GPR74/NPFFR2 Peptides and GPR74/NPFFR2 Proteins can be used in a variety of model species: Human. (novusbio.com)
- Choose from our GPR74/NPFFR2 Peptides and Proteins. (novusbio.com)
- Peptides presented by MHC-I molecules are mainly intracellular and those presented by MHC-II molecules originate mainly from or extracellular proteins. (biomedcentral.com)
Genes4
- All internal genes except PA were similar to influenza virus gene segments found in contemporary triple reassortant (human, swine, avian) SIVs in the United States. (usda.gov)
- Rhombotin 1 (RBTN1 or TTG-1) and rhombotin-2 (RBTN2 or TTG-2) are proteins of about 160 amino acids whose genes are disrupted by chromosomal translocations in T-cell leukemia. (embl.de)
- The MYCN protein regulates the activity of other genes by attaching (binding) to specific regions of DNA and controlling the first step of protein production (transcription). (medlineplus.gov)
- As a result, only half the normal amount of this protein is available to control the activity of specific genes during development. (medlineplus.gov)
Pandemic3
- 3. Preparedness and response in regard to avian influenza and threats of influenza pandemic require concerted action under government leadership with increased urgency and participation of all stakeholders and partners. (who.int)
- Pandemic influenza, and primarily avian influenza, is a serious concern for Egypt. (who.int)
- WHO offers technical support to the NIPEC and participated in the development of the Integrated National Plan for avian and pandemic influenza in response to the rapid spread of avian influenza and pandemic influenza, in collaboration with the Ministry of Agriculture and the Food and Agriculture Organization of the United Nations (FAO). (who.int)
Chickens2
- In addition, genome-edited chickens have been bred which are resistant to the avian leukosis virus. (feedstuffs.com)
- The variant of a certain protein leading to resistance to the avian leukosis virus does not occur in chickens, but is found, for example, in quails. (feedstuffs.com)
H7N91
- In 2013, an outbreak of the avian flu strain H7N9 began in southeastern China. (msdmanuals.com)
Birds3
- In the United States, the most common are avian antigens (derived from birds), mycobacterial antigens (in aerosols derived from hot tub water), and bacteria (derived from moldy hay). (medscape.com)
- Avian influenza is an infectious disease of birds caused by type A strains of the influenza virus. (who.int)
- In birds, highly pathogenic avian influenza is an extremely contagious and aggressive disease that causes rapid systemic illness and death in susceptible birds. (who.int)
Infection2
- Therefore, because of the lack of Avian infectious bronchitis virus (IBV), a member of a vaccine against endemic strains of IBV in China, IBV family Coronaviridae, order Nidovirales, causes a infection has remained a problem in the Chinese poultry highly contagious respiratory and sometimes urogenital industry. (cdc.gov)
- Other strains of the avian flu virus have also caused sporadic outbreaks of infection in people. (msdmanuals.com)
Kinases1
- Vertebrate protein kinases LIMK-1 and LIMK-2. (embl.de)
Infectious1
- A virulent avian infectious bronchitis virus (IBV) was programs in many countries ( 1 - 5 ). (cdc.gov)
Infect humans1
- To confirm that the SR polymorphism was a new pathway for the virus to infect humans, they introduced the mutation into the PB2 protein of the avian influenza. (scienceblog.com)
Virus6
- In their investigation, Mehle and Doudna found that the 2009 H1N1 virus has acquired the SR polymorphism in its PB2 protein that enhances polymerase activity in human cells. (scienceblog.com)
- The avian leukosis virus can lead to severe diseases and severe growth and laying depression in poultry," said Schusser. (feedstuffs.com)
- The vaccinia virus A56 protein was one of the earliest-described poxvirus proteins with an identifiable activity. (microbiologyresearch.org)
- Hepatitis E virus (HEV) ORF1 protein (pORF1) contains methyltransferase (MetT), papain-like cysteine protease (PCP), RNA helicase (Hel) and RNA-dependent RNA polymerase (RdRp) domains. (microbiologyresearch.org)
- And in this case, the New York State Department was able to demonstrate that the clinical specimen from the veterinarian was infected with an avian H7N2 virus, and then the sample was sent to CDC for some confirmatory testing. (cdc.gov)
- All human infections caused by a new influenza subtype are required to be reported under the International Health Regulations (IHR, 2005).4 This includes any influenza A virus that has demonstrated the capacity to infect a human and its haemagglutinin gene (or protein) is not a mutated form of those, i.e. (who.int)
Humans1
- The poultry sector is noted to make a considerable contribution to global nutrition and food security, which helps in the provision of cheap protein, essential micronutrients, and energy to humans ( 1 ). (frontiersin.org)
Clinical1
- Providing the highest quality of education in hematology and clinical pathology for avian and reptiles. (clinicalavianpathologyservices.com)
Receptor2
- The HA protein revealed a Q226L mutation when compared with the putative parental avian HA protein, indicating a preferential binding to SA'2,6Gal, the mammalian influenza receptor. (usda.gov)
- a protein required for the differentiation of the set of six touch receptor neurons in this nematode. (embl.de)
Antiviral1
- MetT-PCP carried out deISGylation of the ISG15-conjugated cellular proteins, suggesting a possible role in combating cellular antiviral pathways. (microbiologyresearch.org)
Genetic1
- These genetic changes prevent one copy of the gene in each cell from producing any functional MYCN protein. (medlineplus.gov)
Amino acid1
- Mammalian and avian cysteine-rich protein (CRP), a 192 amino-acid protein of unknown function. (embl.de)
Poultry1
- A large dependence on poultry as the main form of animal protein consumption in the normal diet means that highly pathogenic avian influenza also poses a significant threat to food security. (who.int)
Haemagglutinin1
- While originally characterized as a haemagglutinin protein, A56 has other functions as well. (microbiologyresearch.org)
Lipid1
- Modulations in lipid A and phospholipid biosynthesis pathways influence outer membrane protein assembly in Escherichia coli K-12. (wikigenes.org)
Mammalian2
- Mammalian LH-2, a transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types. (embl.de)
- Mammalian cysteine-rich intestinal protein (CRIP), a small protein which seems to have a role in zinc absorption and may function as an intracellular zinc transport protein. (embl.de)
Human cases1
- WHO supports the implementation of the National Plan through building capacity in surveillance and monitoring of human cases of avian influenza and ensuring a rapid response. (who.int)
Transcription1
- On the basis of this action, this protein is called a transcription factor. (medlineplus.gov)
Insulin3
- Vertebrate insulin gene enhancer binding protein isl-1. (embl.de)
- Isl-1 binds to one of the two cis-acting protein-binding domains of the insulin gene. (embl.de)
- Studies previously conducted show that HS negatively affects the skeletal muscle growth and development by changing its effects on myogenic regulatory factors, insulin growth factor-1, and heat-shock proteins. (frontiersin.org)
Normal2
- Drosophila melanogaster (Fruit fly) protein apterous, required for the normal development of the wing and halter imaginal discs. (embl.de)
- Studies in animals suggest that this protein is necessary for normal development of the limbs, heart, kidneys, lungs, nervous system, and digestive system. (medlineplus.gov)
Common1
- Helianthus annuus (Common sunflower) pollen specific protein SF3. (embl.de)
Surface1
- while both proteins have biologically relevant functions at the cell surface, neither one can locate there on its own. (microbiologyresearch.org)
Meat1
- HS causes poor meat quality by impairing protein synthesis and augmenting undesirable fat in meat. (frontiersin.org)
Function1
- 5. Koskinen R, Göbel TW, Tregaskes CA, Young JR, Vainio O. The structure of avian CD5 implies a conserved function. (southernbiotech.com)
Shown1
- Zyxin is a low-abundance adhesion plaque protein which has been shown to interact with CRP. (embl.de)
Analysis1
- Analysis of structural models of the RBD proteins with S42 and P42 suggested remarkable difference in the structure of the dsRNA-binding interface, whereas structural analysis by analytical gel filtration and CD measurements did not indicate difference between those RBD proteins. (tokushima-u.ac.jp)
Risk1
- WHO and FAO have established a platform for joint risk assessment on avian influenza where both epidemiological and virological surveillance data are shared regularly and a risk assessment report is developed. (who.int)
Activity1
- The protein encompassing the predicted MetT-PCP domains of HEV ORF1 was tested for deubiquitinating activity using fluorogenic substrates - ubiquitin-7-amino-4-methylcoumarin (AMC), IFN-stimulated gene 15 (ISG15)-AMC, Nedd8-AMC and SUMO-AMC. (microbiologyresearch.org)
