Avian leukosis virus: The type species of ALPHARETROVIRUS producing latent or manifest lymphoid leukosis in fowl.Avian Leukosis: A group of transmissible viral diseases of chickens and turkeys. Liver tumors are found in most forms, but tumors can be found elsewhere.Alpharetrovirus: A genus of the family RETROVIRIDAE with type C morphology, that causes malignant and other diseases in wild birds and domestic fowl.Chickens: Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.Avian Sarcoma Viruses: Group of alpharetroviruses (ALPHARETROVIRUS) producing sarcomata and other tumors in chickens and other fowl and also in pigeons, ducks, and RATS.Bursa of Fabricius: An epithelial outgrowth of the cloaca in birds similar to the thymus in mammals. It atrophies within 6 months after birth and remains as a fibrous remnant in adult birds. It is composed of lymphoid tissue and prior to involution, is the site of B-lymphocyte maturation.Avian Proteins: Proteins obtained from species of BIRDS.Chick Embryo: The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.Poultry Diseases: Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.Receptors, Virus: Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response.Reticuloendotheliosis virus: A species in the group RETICULOENDOTHELIOSIS VIRUSES, AVIAN of the genus GAMMARETROVIRUS that causes a chronic neoplastic and a more acute immunosuppressive disease in fowl.Sarcoma, Avian: Connective tissue tumors, affecting primarily fowl, that are usually caused by avian sarcoma viruses.Quail: Common name for two distinct groups of BIRDS in the order GALLIFORMES: the New World or American quails of the family Odontophoridae and the Old World quails in the genus COTURNIX, family Phasianidae.Genes, pol: DNA sequences that form the coding region for retroviral enzymes including reverse transcriptase, protease, and endonuclease/integrase. "pol" is short for polymerase, the enzyme class of reverse transcriptase.Coturnix: A genus of BIRDS in the family Phasianidae, order GALLIFORMES, containing the common European and other Old World QUAIL.DNA, Viral: Deoxyribonucleic acid that makes up the genetic material of viruses.Genes, env: DNA sequences that form the coding region for the viral envelope (env) proteins in retroviruses. The env genes contain a cis-acting RNA target sequence for the rev protein (= GENE PRODUCTS, REV), termed the rev-responsive element (RRE).Proviruses: Duplex DNA sequences in eukaryotic chromosomes, corresponding to the genome of a virus, that are transmitted from one cell generation to the next without causing lysis of the host. Proviruses are often associated with neoplastic cell transformation and are key features of retrovirus biology.Genes, gag: DNA sequences that form the coding region for proteins associated with the viral core in retroviruses. gag is short for group-specific antigen.Avian myeloblastosis virus: A species of ALPHARETROVIRUS causing anemia in fowl.Virus Replication: The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.Hemangioma: A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)Defective Viruses: Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.Herpesvirus 2, Gallid: The type species of the genus MARDIVIRUS in the family HERPESVIRIDAE. It is the etiologic agent of MAREK DISEASE, infecting domestic fowl and wild birds.RNA, Viral: Ribonucleic acid that makes up the genetic material of viruses.Marek Disease: A transmissible viral disease of birds caused by avian herpesvirus 2 (HERPESVIRUS 2, GALLID) and other MARDIVIRUS. There is lymphoid cell infiltration or lymphomatous tumor formation in the peripheral nerves and gonads, but may also involve visceral organs, skin, muscle, and the eye.Genes, Viral: The functional hereditary units of VIRUSES.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.Endogenous Retroviruses: Retroviruses that have integrated into the germline (PROVIRUSES) that have lost infectious capability but retained the capability to transpose.Repetitive Sequences, Nucleic Acid: Sequences of DNA or RNA that occur in multiple copies. There are several types: INTERSPERSED REPETITIVE SEQUENCES are copies of transposable elements (DNA TRANSPOSABLE ELEMENTS or RETROELEMENTS) dispersed throughout the genome. TERMINAL REPEAT SEQUENCES flank both ends of another sequence, for example, the long terminal repeats (LTRs) on RETROVIRUSES. Variations may be direct repeats, those occurring in the same direction, or inverted repeats, those opposite to each other in direction. TANDEM REPEAT SEQUENCES are copies which lie adjacent to each other, direct or inverted (INVERTED REPEAT SEQUENCES).RNA-Directed DNA Polymerase: An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.Viral Interference: A phenomenon in which infection by a first virus results in resistance of cells or tissues to infection by a second, unrelated virus.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Tenosynovitis: Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.Culture Techniques: Methods of maintaining or growing biological materials in controlled laboratory conditions. These include the cultures of CELLS; TISSUES; organs; or embryo in vitro. Both animal and plant tissues may be cultured by a variety of methods. Cultures may derive from normal or abnormal tissues, and consist of a single cell type or mixed cell types.Enzootic Bovine Leukosis: A lymphoid neoplastic disease in cattle caused by the bovine leukemia virus. Enzootic bovine leukosis may take the form of lymphosarcoma, malignant lymphoma, or leukemia but the presence of malignant cells in the blood is not a consistent finding.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Recombination, Genetic: Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.Virus Integration: Insertion of viral DNA into host-cell DNA. This includes integration of phage DNA into bacterial DNA; (LYSOGENY); to form a PROPHAGE or integration of retroviral DNA into cellular DNA to form a PROVIRUS.Retroviridae: Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES).Oncogenes: Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.Cytopathogenic Effect, Viral: Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.Birds: Warm-blooded VERTEBRATES possessing FEATHERS and belonging to the class Aves.Retroviridae Proteins: Proteins from the family Retroviridae. The most frequently encountered member of this family is the Rous sarcoma virus protein.Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.Antigens, Viral: Substances elaborated by viruses that have antigenic activity.Viral Envelope Proteins: Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Genetic Vectors: DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.Nucleic Acid Hybridization: Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)RNA Viruses: Viruses whose genetic material is RNA.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Viral Proteins: Proteins found in any species of virus.Helper Viruses: Viruses which enable defective viruses to replicate or to form a protein coat by complementing the missing gene function of the defective (satellite) virus. Helper and satellite may be of the same or different genus.Vaccinia virus: The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Genome, Viral: The complete genetic complement contained in a DNA or RNA molecule in a virus.Virus Cultivation: Process of growing viruses in live animals, plants, or cultured cells.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Sequence Homology, Nucleic Acid: The sequential correspondence of nucleotides in one nucleic acid molecule with those of another nucleic acid molecule. Sequence homology is an indication of the genetic relatedness of different organisms and gene function.Histiocytic Sarcoma: Malignant neoplasms composed of MACROPHAGES or DENDRITIC CELLS. Most histiocytic sarcomas present as localized tumor masses without a leukemic phase. Though the biological behavior of these neoplasms resemble lymphomas, their cell lineage is histiocytic not lymphoid.

Genome structure and expression of the ev/J family of avian endogenous viruses. (1/808)

We recently reported the identification of sequences in the chicken genome that show over 95% identity to the novel envelope gene of the subgroup J avian leukosis virus (S. J. Benson, B. L. Ruis, A. M. Fadly, and K. F. Conklin, J. Virol. 72:10157-10164, 1998). Based on the fact that the endogenous subgroup J-related env genes were associated with long terminal repeats (LTRs), we concluded that these LTR-env sequences defined a new family of avian endogenous viruses that we designated the ev/J family. In this report, we have further characterized the content and expression of the ev/J proviruses. The data obtained indicate that there are between 6 and 11 copies of ev/J proviruses in all chicken cells examined and that these proviruses fall into six classes. Of the 18 proviruses examined, all share a high degree of sequence identity and all contain an internal deletion that removes all of the pol gene and various amounts of gag and env gene sequences. Sequencing of the gag genes, LTRs, and untranslated regions of several ev/J proviruses revealed a high level of identity between isolates, indicating that they have not undergone significant sequence variation since their introduction into the avian germ line. Although the ev/J gag gene showed a relatively weak relationship (46% identity and 61% similarity at the amino acid level) to that of the avian leukosis-sarcoma virus family, it retains several sequences of demonstrated importance for virus assembly, budding, and/or infectivity. Finally, evidence was obtained that at least some members of the ev/J family are expressed and, if translated, could encode Gag- and Env-related polypeptides.  (+info)

Evidence of avian leukosis virus subgroup E and endogenous avian virus in measles and mumps vaccines derived from chicken cells: investigation of transmission to vaccine recipients. (2/808)

Reverse transcriptase (RT) activity has been detected recently in all chicken cell-derived measles and mumps vaccines. A study of a vaccine manufactured in Europe indicated that the RT is associated with particles containing endogenous avian retrovirus (EAV-0) RNA and originates from the chicken embryonic fibroblasts (CEF) used as a substrate for propagation of the vaccine. We investigated the origin of RT in measles and mumps vaccines from a U.S. manufacturer and confirm the presence of RT and EAV RNA. Additionally, we provide new evidence for the presence of avian leukosis virus (ALV) in both CEF supernatants and vaccines. ALV pol sequences were first identified in particle-associated RNA by amplification with degenerate retroviral pol primers. ALV RNA sequences from both the gag and env regions were also detected. Analysis of hypervariable region 2 of env revealed a subgroup E sequence, an endogenous-type ALV. Both CEF- and vaccine-derived RT activity could be blocked by antibodies to ALV RT. Release of ALV-like virus particles from uninoculated CEF was also documented by electron microscopy. Nonetheless, infectivity studies on susceptible 15B1 chicken cells gave no evidence of infectious ALV, which is consistent with the phenotypes of the ev loci identified in the CEF. PCR analysis of ALV and EAV proviral sequences in peripheral blood mononuclear cells from 33 children after measles and mumps vaccination yielded negative results. Our data indicate that the sources of RT activity in all RT-positive measles and mumps vaccines may not be similar and depend on the particular endogenous retroviral loci present in the chicken cell substrate used. The present data do not support transmission of either ALV or EAV to recipients of the U.S.-made vaccine and provide reassurance for current immunization policies.  (+info)

An avian sarcoma/leukosis virus-based gene trap vector for mammalian cells. (3/808)

RCASBP-M2C is a retroviral vector derived from an avian sarcoma/leukosis virus which has been modified so that it uses the envelope gene from an amphotropic murine leukemia virus (E. V. Barsov and S. H. Hughes, J. Virol. 70:3922-3929, 1996). The vector replicates efficiently in avian cells and infects, but does not replicate in, mammalian cells. This makes the vector useful for gene delivery, mutagenesis, and other applications in mammalian systems. Here we describe the development of a derivative of RCASBP-M2C, pGT-GFP, that can be used in gene trap experiments in mammalian cells. The gene trap vector pGT-GFP contains a green fluorescent protein (GFP) reporter gene. Appropriate insertion of the vector into genes causes GFP expression; this facilitates the rapid enrichment and cloning of the trapped cells and provides an opportunity to select subpopulations of trapped cells based on the subcellular localization of GFP. With this vector, we have generated about 90 gene-trapped lines using D17 and NIH 3T3 cells. Five trapped NIH 3T3 lines were selected based on the distribution of GFP in cells. The cellular genes disrupted by viral integration have been identified in four of these lines by using a 5' rapid amplification of cDNA ends protocol.  (+info)

Studies of the genomic RNA of leukosis viruses: implications for RNA dimerization. (4/808)

Retroviral particles contain two positive-strand genomic RNAs linked together by noncovalent bonds that can be dissociated under mild conditions. We studied genomic RNAs of wild-type and mutant avian leukosis viruses (ALVs) in an attempt to (i) better understand the site(s) of RNA dimerization, (ii) examine whether the primer binding site (PBS) and tRNA primer are involved in dimerization, and (iii) determine the structure of genomic RNA in protease-deficient (PR(-)) mutants. We showed that extensively nicked wild-type ALV genomic RNAs melt cooperatively. This implies a complex secondary and/or tertiary structure for these RNAs that extends well beyond the 5' dimerization site. To investigate the role of the PBS-tRNA complex in dimerization, we analyzed genomic RNAs from mutant viruses in which the tRNA(Trp) PBS had been replaced with sequences homologous to the 3' end of six other chicken tRNAs. We found the genomic RNAs of these viruses are dimers that dissociate at the same temperature as wild-type viral RNA, which suggests that the identity of the PBS and the tRNA primer do not affect dimer stability. We studied two ALV PR(-) mutants: one containing a large (>1.9-kb) inversion spanning the 3' end of gag and much of pol, rendering it deficient in PR, reverse transcriptase, and integrase, and another with a point mutation in PR. In both of these mutant viruses, the genomic RNA appears to be either primarily or exclusively monomeric. These data suggest that ALV can package its RNA as monomers that subsequently dimerize.  (+info)

Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect. (5/808)

The 3' untranslated region (3' UTR) between the 3' end of env and the long terminal repeat is well conserved among avian retroviruses and is essential for efficient replication. Deletion of the dr1 element within the 3' UTR has been reported to have various effects, including reduced levels of unspliced RNA in the cytoplasm, decreased stability of unspliced RNA, decreased particle production, and decreased genomic RNA packaging. To probe the role of specific sequences within dr1 in virus replication, site-directed mutagenesis was utilized to perturb parts of the predicted secondary structure of dr1. Seven of thirteen mutations had no significant effect; the others resulted in an approximately 10- to 20-fold reduction in replication. These mutants were further characterized and found to impair cytoplasmic accumulation of unspliced RNA only slightly. Furthermore, no decreases were observed in the stability of the unspliced RNA or in the production of virus particles. Genomic RNA packaging, however, was reduced by about 10-fold. Similar amounts of particles were produced by cells containing the mutant and wild-type DNA, and all particles contained similar levels of reverse transcriptase activity. The results suggest that the region of the dr1 disrupted by the mutations plays a role in genomic RNA packaging, although that packaging may not be the only role for dr1.  (+info)

Retroviral vectors preloaded with a viral receptor-ligand bridge protein are targeted to specific cell types. (6/808)

Successful targeting methods represent a major hurdle to the use of retroviral vectors in cell-specific gene-delivery applications. We recently described an approach for retroviral targeting with a retroviral receptor-ligand bridge protein that was bound to the cognate cell-surface ligand receptors before viral challenge. We now report a significant improvement made to this viral targeting method by using a related bridge protein, designated TVB-EGF, comprised of the extracellular domain of the TVB receptor for subgroup B avian leukosis virus fused to epidermal growth factor (EGF). The most important activity of TVB-EGF was that it allowed specific viral entry when preloaded onto virions. Furthermore, virions preloaded with TVB-EGF were thermostable and could be produced directly from virus- packaging cells. These data suggest an approach for targeting retroviral vectors to specific cell types by using virions preloaded with a retroviral receptor-ligand bridge protein and indicate that these types of bridge proteins may be useful reagents for studying the normal mechanism of retroviral entry.  (+info)

Production and design of more effective avian replication-incompetent retroviral vectors. (7/808)

Retroviral vectors have been invaluable tools for studies of development in vertebrates. Their use has been somewhat constrained, however, by the low viral titers typically obtained with replication-incompetent vectors, particularly of the avian type. We have addressed this problem in several ways. We optimized the transient production of avian replication-incompetent viruses in a series of cell lines. One of the optimal cell lines was the mammalian line 293T, which was surprising in light of previous reports that avian viral replication was not supported by mammalian cells. We also greatly increased the efficiency of viral infection. Pseudotyping with the vesicular stomatitus virus G (VSV-G) protein led to an over 350-fold increase in the efficiency of infection in ovo relative to infection with virus particles bearing an avian retroviral envelope protein. To further increase the utility of the system, we developed new Rous sarcoma virus (RSV)-based replication-incompetent vectors, designed to express a histochemical marker gene, human placental alkaline phosphatase, as well as an additional gene. These modified retroviral vectors and the VSV-G pseudotyping technique constitute significant improvements that allow for expanded use of avian replication-incompetent viral vectors in ovo.  (+info)

A genetically engineered cell line resistant to subgroup J avian leukosis virus infection (C/J). (8/808)

A cell line (DF-1 inverted question markJ) expressing the envelope protein isolated from the ADOL-Hc1 strain of the avian leukosis virus subgroup J (ALV-J) was used to analyze receptor interference to six different isolates of ALV-J as well as ALV subgroups A-D. The traditional gag-specific enzyme-linked immunosorbent assay (ELISA) as well as flow cytometry was used to evaluate viral infection. The parental cell line (DF-1) was susceptible to all ALV subgroups tested while the DF-1 inverted question markJ cell line was selectively resistant to the subgroup J isolates. The DF-1 inverted question markJ cell line was resistant to infection by all six ALV-J isolates as determined using the gag-specific ELISA. There was no interference with the other ALV subgroups (A-D) induced by the expression of the ADOL-Hcl envelope. The ALV-J isolates used in this analysis are serologically distinct when analyzed by flow cytometry. Convalescent sera to ADOL-Hcl cross-reacts with all of the ALV-J isolates tested; however, sera to HPRS-103 did not bind to four of the six isolates. Based on the intensity and differential binding of these antisera using flow cytometry, the six ALV-J isolates used can be grouped into four categories. Thus the DF-1 inverted question markJ cell line is resistant to infection by a serologically and genetically diverse group of ALV-J isolates and should be useful as a diagnostic tool.  (+info)

*Retrovirus

Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ... Genus Betaretrovirus; type species: Mouse mammary tumour virus. *Genus Gammaretrovirus; type species: Murine leukemia virus; ... "Virus Taxonomy: 2018b Release" (html). International Committee on Taxonomy of Viruses (ICTV). March 2019. Retrieved 16 March ... Group VII viruses[edit]. Both families in Group VII have DNA genomes contained within the invading virus particles. The DNA ...

*Peter K. Vogt

Rubin, H; Vogt PK (1962). "An avian leukosis virus associated with stocks of Rous sarcoma virus". Virology. 17: 184-94. doi: ... "Criteria for the classification of avian tumor viruses". Viruses Inducing Cancer. Salt Lake City: University of Utah Press: 71- ... Maki, Y; Bos TJ; Davis C; Starbuck M; Vogt PK (1987). "Avian sarcoma virus 17 carries the jun oncogene". Proc Natl Acad Sci U S ... "Nobel Prize 1989". Duesberg, PH; Bister K; Vogt PK (1977). "The RNA of avian acute leukemia virus MC29". Proc Natl Acad Sci U S ...

*Specific-pathogen-free

Lymphoid Leukosis A, B; Avian Lymphoid Leukosis Virus; Lymphoid Leukosis Viruses A,B,C,D,E,J; Marek's Disease (Serotypes 1,2, 3 ... Avian Nephritis Virus, Avian Paramyxovirus Type 2, Avian Reovirus S 1133, Avian Rhinotracheitis Virus; Avian Rotavirus; Avian ... Avian Adenovirus Group II (HEV), Avian Adenovirus Group III (EDS), Avian Encephalomyelitis, Avian Influenza (Type A), ... For SPF eggs the specific pathogens are: Avian Adenovirus Group I, ...

*Alpharetrovirus

Species include the Rous sarcoma virus, avian leukosis virus, and avian myeloblastosis virus. Alpharetrovirus at the US ...

*Lymphoid leucosis

... caused by the retrovirus Avian leukosis virus. It is a neoplastic disease caused by a virus, which may take the form of a tumor ...

*NFKBIE

Curristin SM, Bird KJ, Tubbs RJ, Ruddell A (1997). "VBP and RelA regulate avian leukosis virus long terminal repeat-enhanced ...

*Retrovirus direct repeat 1 (dr1)

Rous sarcoma and Avian leukosis viruses (Alpharetroviruses and Avian type C retroviruses). dr1 is required for efficient viral ... Aschoff, JM; Foster D; Coffin JM (1999). "Point Mutations in the Avian Sarcoma/Leukosis Virus 3′ Untranslated Region Result in ... The direct repeat 1 (dr1) element is an RNA element commonly found in the 3' UTR of Avian sarcoma, ...

*Insertional mutagenesis

Avian leukosis virus is an example of a virus that causes a disease by insertional mutagenesis. Newly hatched chicks infected ... with Avian leukosis virus will begin to form tumours that will begin to appear in their bursa of fabricus (like the human ... Virus insertional mutagenesis is possible with both replication competent virus and the self-inactivating vectors that are ... The virus inserts a gene (known as a viral onocogene) normally near the cellular myc (c-myc)gene. The c-myc gene is normally ...

*Env (gene)

The Env proteins of the Avian Sarcoma and Leukosis virus (ASLV) and the Murine Leukemia Virus (MLV) are both trimers of SU-TM ... Avian Sarcoma and Leukosis Viruses (ASLV) have ten subgroups (A through J). The envelope glycoprotein of subgroup A is called ... Balliet JW, Gendron K, Bates P (April 2000). "Mutational analysis of the subgroup A avian sarcoma and leukosis virus putative ... "Low pH is required for avian sarcoma and leukosis virus Env-dependent viral penetration into the cytosol and not for viral ...

*Syndemic

... for instance between Avian sarcoma leukosis virus and Marek's disease virus (MDV) in domestic fowl.[citation needed] Both ... In coinfected cells, the retroviral DNA of the avian leukosis virus can integrate into the MDV genome, producing altered ... The drop in HIV virus levels may be due to a lack of target CD4+ T cells in which they replicate, or measles virus may ... Bini Edmund; Perumalswami Ponni (2010). "Hepatitis B Virus Infection Among American Patients with Chronic Hepatitis C Virus ...

*Endogenous viral element

Ancient DNA Avian sarcoma leukosis virus (ASLV) Endogenous retrovirus ERV3 HERV-FRD Jaagsiekte sheep retrovirus (JSRV) Koala ... Murine leukemia virus (MLV), and xenotropic murine leukemia virus-related virus (XMRV) Paleovirology Polydnavirus Viral ... An endogenous viral element (EVE) is a DNA sequence derived from a virus, and present within the germline of a non-viral ... For most non-retroviral viruses, germline integration appears to be a rare, anomalous event, and the resulting EVEs are often ...

*Retrovirus

Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ... Such viruses are either single stranded RNA (e.g. HIV) or double stranded DNA (e.g. Hepatitis B virus) viruses. ... Genus Betaretrovirus; type species: Mouse mammary tumour virus. *Genus Gammaretrovirus; type species: Murine leukemia virus; ... "Virus Taxonomy: 2018b Release" (html). International Committee on Taxonomy of Viruses (ICTV). March 2019. Retrieved 16 March ...

*Oncovirus

1908: Vilhelm Ellerman and Olaf Bang, University of Copenhagen, first demonstrated that avian sarcoma leukosis virus could be ... DNA virus. HBV (B). RNA virus. CBV. HAV (A). HCV (C). HDV (D). HEV (E). HGV (G). ... RNA viruses[edit]. Not all oncoviruses are DNA viruses. Some RNA viruses have also been associated such as the hepatitis C ... DNA viruses[edit]. *Human papilloma virus (HPV), a DNA virus, causes transformation in cells through interfering with tumor ...

*Reticuloendotheliosis virus

... after Marek's disease and avian leukosis virus. The various syndromes caused by REV resemble both Marek's and avian leukosis. ... Reticuloendotheliosis virus represents a third distinct etiological group of avian viral neoplasms, ... MI is the primary laboratory for research in REV and other tumor viruses. The American Association of Avian Pathologists ... "Avian Diagnostic and Oncology Laboratory". "Frequently Asked Questions on Viral Tumor Diseases - Compiled by the AAAP Tumor ...

*Leucosis

... horses Leucosis in sheep Feline leucosis Feline leukemia virus Avian leucosis and related diseases Avian sarcoma leukosis virus ... ISBN 0-7020-0718-8. H. Graham Purchase and L.N. Payne, Leukosis/sarcoma Group, in Diseases of poultry, ed. by M.S. Hofstad, ... Bovine leucosis Enzootic bovine leucosis, caused by bovine leukemia virus. Sporadic bovine leucosis Calf lymphosarcoma Leucosis ... "Bovine leukemia virus". The dictionary of virology (4th ed.). Amsterdam: Elsevier/Academic Press. pp. 61-62. ISBN 9780080920368 ...

*ALV

Avian leukosis virus Autoliv (ticker symbol). ...

*Endogenous retrovirus

Viruses portal Avian sarcoma leukosis virus (ASLV) Endogenous viral element ERV3 HERV-FRD Horizontal gene transfer Jaagsiekte ... "Reactivated Virus May Contribute to ALS". Yolken R (June 2004). "Viruses and schizophrenia: a focus on herpes simplex virus". ... Murine leukemia virus (MLV) and xenotropic murine leukemia virus-related virus (XMRV) Paleovirology Belshaw R, Pereira V, ... On viruses, sex, and motherhood (1997). "On viruses, sex, and motherhood". J Virol. 71 (2): 859-865. PMC 191132 . PMID 8995601 ...

*Poultry disease

Chicken anaemia virus Lymphoid leucosis caused by avian sarcoma leukosis virus Marek's disease Newcastle disease Viral ... arthritis Turkeypox virus Scaly leg, caused by the mite Knemidocoptes mutans Infestions: Dermanyssus gallinae, the red poultry ...

*List of MeSH codes (C04)

... avian leukosis MeSH C04.619.935.313 --- epstein-barr virus infections MeSH C04.619.935.313.165 --- burkitt lymphoma MeSH ... enzootic bovine leukosis MeSH C04.557.337.372 --- leukemia, experimental MeSH C04.557.337.372.216 --- avian leukosis MeSH ... avian leukosis MeSH C04.619.531.594 --- leukemia l1210 MeSH C04.619.531.602 --- leukemia l5178 MeSH C04.619.531.782 --- ... avian MeSH C04.557.450.795.830.850 --- sarcoma, yoshida MeSH C04.557.450.795.840 --- sarcoma, granulocytic MeSH C04.557.450.795 ...

*Oncovirus

1908: Vilhelm Ellerman and Olaf Bang, University of Copenhagen, first demonstrated that avian sarcoma leukosis virus could be ... Tumor viruses come in a variety of forms: Viruses with a DNA genome, such as adenovirus, and viruses with an RNA genome, like ... It now refers to any virus with a DNA or RNA genome causing cancer and is synonymous with "tumor virus" or "cancer virus". The ... The main viruses associated with human cancers are human papillomavirus, hepatitis B and hepatitis C virus, Epstein-Barr virus ...

*Avian immune system

The most common immunosuppressive viruses are Infectious Bursal Disease Virus (IBDV), Avian Leukosis, Marek's Disease (MD) and ... "Development of the Avian Immune System." Avian Immunology. 4:51-66. Masteller EL, Pharr GT, Funk PE, Thompson CB (1997). "Avian ... Infectious bursal disease virus and chicken anemia are ubiquitous and have increased interest in combatting avian pathogens. ... Jenkins KA, Bean AG, Lowenthal JW (2007). "Avian genomics and the innate immune response to viruses." Cytogenet. Genome Res. ...

*Avian sarcoma leukosis virus

"Avian sarcoma and leukosis virus-receptor interactions: from classical genetics to novel insights into virus-cell membrane ... Avian sarcoma leukosis virus is characterized by a wide range of tumors, the most common of which are lymphomas. Lymphoid ... Avian sarcoma leukosis virus (ASLV) is an endogenous retrovirus that infects and can lead to cancer in chickens; experimentally ... ISBN 978-1-118-71973-2. Riddell, C. (May-June 1999). "The current problem with Avian Leukosis J Virus". California Poultry ...

*Sex link

Avian influenza. *Avian sarcoma leukosis virus. *Histomoniasis (blackhead disease). *Botulism. *Campylobacteriosis. * ...

*Feather pecking

Avian influenza. *Avian sarcoma leukosis virus. *Histomoniasis (blackhead disease). *Botulism. *Campylobacteriosis. * ... Avian Biology Research, 1: 73-87 *^ Dixon, L.M., Duncan, I.J.H. and Mason, G.J., 2010. The effects of four types of enrichment ... G., (2010). Avian magnetoreception: Elaborate iron mineral containing dendrites in the upper beak seem to be a common feature ...

*Transporter Classification Database

Family 1.G.12 The Avian Leukosis Virus gp95 Fusion Protein (ALV-gp95) Family 1.G.13 The Orthoreovirus Fusion-associated Small ... 1.A.39 Type C influenza virus CM2 channel family 1.A.40 Human immunodeficiency virus type I Vpu channel family 1.A.41 Avian ... 1.A.58 The Type B Influenza Virus Matrix Protein 2 (BM2-C) Family 1.A.59 The Bursal Disease Virus Pore-Forming Peptide, Pep46 ( ... Family 1.G.16 The Human Immunodeficiency Virus Type 1 (HIV-1) Fusion Peptide (HIV-FP) Family 1.G.17 The Bovine Leukemia Virus ...

*dsDNA-RT virus

ssRNA-RT virus. Retroviridae. Alpharetrovirus. *Avian sarcoma leukosis virus. *Rous sarcoma virus ... dsDNA-RT viruses are the seventh group in the Baltimore virus classification. They are not considered DNA viruses (class I of ... Khan, Jawaid A.; Dijkstra, Jeanne (2002). Plant viruses as molecular pathogens. Psychology Press. pp. 317-. ISBN 978-1-56022- ... Retrieved from "https://en.wikipedia.org/w/index.php?title=DsDNA-RT_virus&oldid=748922731" ...

*Category:Low-importance virus articles

Talk:Avian reovirus. *Talk:Avian reovirus (version 2). *Talk:Avian sarcoma leukosis virus ... Pages in category "Low-importance virus articles". The following 200 pages are in this category, out of approximately 1,493 ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Category:Low-importance_virus_articles&oldid=388350164" ...

*List of MeSH codes (B04)

... avian MeSH B04.820.650.070.500 --- leukosis virus, avian MeSH B04.820.650.070.550 --- myeloblastosis virus, avian MeSH B04.820. ... avian MeSH B04.909.574.807.070.500 --- leukosis virus, avian MeSH B04.909.574.807.070.550 --- myeloblastosis virus, avian MeSH ... avian MeSH B04.909.777.731.070.500 --- leukosis virus, avian MeSH B04.909.777.731.070.550 --- myeloblastosis virus, avian MeSH ... yellow fever virus MeSH B04.820.250.400 --- gb virus a MeSH B04.820.250.405 --- gb virus b MeSH B04.820.250.410 --- GB virus C ...
The host ranges of the Rous sarcoma virus (RSV) pseudotype RSV(HPRS-103) of a novel avian leukosis virus (ALV), strain HPRS-103, and representative RSV pseudotypes of subgroups A to F, have been determined in embryo fibroblasts from 12 avian species. Domestic fowl, red jungle fowl, Sonnerat's jungle fowl and turkey were susceptible to infection by RSV(HPRS-103); ring-necked pheasant, Japanese green pheasant, golden pheasant, Japanese quail, guinea-fowl, Peking duck, Muscovy duck and goose were resistant. The host range pattern of RSV(HPRS-103) differs from those of viruses of subgroups A to G and I, and provides support for placing the HPRS-103 strain of ALV in a new envelope subgroup, designated J.
We have previously described avian leukosis virus-based packaging cell lines that express gag, pol, and env proteins from two transcomplementing genomes and produce helper-free stocks of retroviral vectors with different host ranges. In this report, we demonstrated that (i) despite the deletion of the psi packaging sequence, the packaging-defective transcomplementing retroviral transcripts were packaged into virions at a level that could reach 2.3% of a wild-type virus packaging level and (ii) despite deletion of the 3 LTR, these genomes were transferred along with the vector to target cells. As these genomes were also bearing a selectable gene, titers of the resulting contaminant particles could be estimated, depending on the cell line to be between 0 and 6 infectious particles/ml of supernatant.
Traditionally, virus isolates have been named most commonly for the disease from which they were isolated - e.g. influenza, poliomyelitis, visna, foot-and-mouth disease, and the like. A smaller number are named for the place of isolation - Coxsackie, Sindbis, and Sendai viruses are a few examples, and a mercifully small number are named for their discoverers - alone or in combination with other features - such as Epstein-Barr virus, Rous sarcoma virus, etc. With retroviruses, it is also usual to append the species of origin to the name - avian leukosis virus, human T-cell lymphoma virus, baboon endogenous virus, etc. Unlike most other organisms, the naming of new virus isolates has usually been a trivial prerogative of the isolator, and not subject to review by other workers in the field . This has, in general, caused little difficulty so long as the names chosen were novel and did not presuppose unproven relationships. Significant confusion has been created in the past, however, by injudicious ...
Induction of lymphomas in the bursa of Fabricius of chickens by replication competent, non-transforming avian retroviruses (Avian Leukosis Virus, ALV) is both an economically significant, naturally...
A team led by Xin Li, Ph.D., assistant professor in the departments of Biochemistry and Biophysics and Urology at the University of Rochester School of Medicine and Dentistry, analyzed rooster testes to find out.. Chickens acquire and harbor a wide variety of viruses. When a virus infects a host, like a chicken, it does everything it can to survive. One method of survival is inserting its genetic material into the chickens genome. Over generations, the inserted virus accumulates mutations and eventually becomes harmless to the animal, but its still a part of the chickens genetic material.. Lis team focused on avian leukosis virus, which commonly infects and can lead to cancer in domestic chickens. Through molecular and genetic analysis, they discovered that chickens turn these old, existing viruses into piRNA-producing machines. When faced with a new avian leucosis virus (there are many different viruses in the family), the old viruses pump out piRNAs that defend the germ cells, ensuring the ...
The avian acute leukemia virus (E26) induces a mixed erythroidmyeloid leukemia in chickens and carries two distinct oncogenes, v-myb and v-ets. The viral protein responsible for transformation is a gag-myb-ets fusion protein that is located in the nucleus of the transformed cells. The cellular homologue of v-ets (c-ets-1) is highly expressed in lymphoid cells and differs from the v-ets gene at its carboxy terminal region. Here, we show that both the c-ets-1 and v-ets gene products are DNA-binding proteins and their DNA-binding activity is located in the carboxy terminal (46 amino acid residues) region. It appears that this DNA-binding activity is modulated by the extreme carboxy terminal region. The amino acid sequences of the putative ets DNA-binding domain at its carboxy terminal region showed a helix-turn-helix secondary structure. Exchanging the nonhomologous extreme carboxy terminal regions of c-ets-1 with v-ets gene sequences showed differences in DNA-binding affinity, indicating that ...
ETS1 (phospho Thr38) antibody (E26 avian leukemia oncogene 1, 5 domain) for ICC/IF, IHC-P, WB. Anti-ETS1 (phospho Thr38) pAb (GTX55307) is tested in Human, Mouse samples. 100% Ab-Assurance.
... the new chromosomal fragment do- nated to a merozygote (q.v.). exogenous DNA DNA that originates outside an organism (e.g., from another cell or virus). exogenous virus a virus ...
/PRNewswire/ -- Autoliv, Inc., the worldwide leader in automotive safety systems, (NYSE: ALV and SSE: ALIVsdb) today announced the results of its annual...
Incidence of avian leukosis virus infection in broiler stocks and its effect on early growth.: Twenty-eight broiler breeder flocks were tested for avian leukosi
Subgroups A, B, E and J are the major subgroups of avian leukosis virus (ALV) infecting chickens. ALV infection has become endemic in China and has a significant negative effect on the poultry industry. Consequently, there is an urgent need for a specific, sensitive and rapid method for diagnosis and eradication of ALV. Therefore, we developed a simple and rapid real-time loop-mediated isothermal amplification (LAMP) reaction for the timely detection of the common ALV subgroups, whereby the amplification can be obtained in 35 min under isothermal conditions at 63 °C, ability to specific, sensitive and rapid detect all the common ALV subgroups. A set of four specific primers was designed to target the sequences of the pol gene of ALV, and the loop-mediated isothermal amplification (LAMP) assay were developed and compared with PCR and virus isolation methods. The results from specificity of the LAMP assay showed that only target ALVs DNA was amplified. The LAMP assay demonstrated a sensitivity of 20
Chicken endogenous viruses, ALVE (Avian Leukosis Virus subgroup E), are inherited as LTR (long terminal repeat) retrotransposons, which are negatively correlated with disease resistance, and any changes in DNA methylation may contribute to the susceptibility to neoplastic disease. The relationship between ALVE methylation status and neoplastic disease in the chicken is undefined. White Leghorn inbred lines 72 and 63 at the ADOL have been respectively selected for resistance and susceptibility to tumors that are induced by avian viruses. In this study, the DNA methylation patterns of 3∼6 CpG sites of four conserved regions in ALVE, including one unique region in ALVE1, the promoter region in the TVB (tumor virus receptor of ALV subgroup B, D and E) locus, were analyzed in the two lines using pyrosequencing methods in four tissues, i.e., liver, spleen, blood and hypothalamus. A significant CpG hypermethylation level was seen in line 72 in all four tissues, e.g., 91.86±1.63% for ALVE region2 in blood,
Morbidity is low but mortality high. Mortality tends to be chronically higher than normal for a prolonged period. Egg production is somewhat reduced. There may be increased susceptibility to other infectious diseases due to damage to the immune system. Vertical transmission is most important by infection of the egg white in infected breeders (who are long-term carriers), lateral transmission is poor but infection may occur by the faecal-oral route, especially in young birds. In lymphoid leukosis the incubation period is about 4-6 months; it may be as short as 6 weeks for some of the other manifestations. The causative viruses are rapidly inactivated at ambient temperature and on exposure to most disinfectants ...
Avian leukosis virus (ALV)-induced osteopetrosis is a proliferative disorder of the bone affecting the growth and differentiation of osteoblasts. Osteopetrosis is a polyclonal disease in which cells of the bone contain, on average, multiple viral DNA copies. Osteopetrotic bone is also characterized by the accumulation of unintegrated viral DNA, suggesting an atypical life cycle of the virus in the infected osteoblasts. To better understand virus-host interactions in the induction of osteopetrosis by ALVs, infected chick osteoblast cultures and osteopetrotic bone were examined for aspects of the virus life cycle and effects of infection on osteoblast function. Levels of infection and virus expression were compared in cultured osteoblasts and osteopetrotic bone. Osteopetrotic bone contained higher levels of viral DNA and correspondingly higher levels of viral proteins than infected osteoblast cultures, suggesting a higher viral load in the diseased bone. A significant level of mature Gag protein was
In addition to neoplasias caused in chickens by helper viruses of the avian myeloblastosis virus (AMV) complex, acute myeloblastic leukemia is induced by a defective leukemogenic component. To...
Avian myeloblastosis ATCC ® VR-1542AS-Gt™ Designation: antiserum against AMV RT [NCI HE 599] Application: goat antiserum against the Avian Myeloblastosis Virus (AMV) Reverse Transcriptase (RT)
TY - JOUR. T1 - Disease tropism of c-erbB. T2 - Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation. AU - Pelley, R. J.. AU - Maihle, Nita Jane. AU - Boerkoel, C.. AU - Shu, H. K.. AU - Carter, T. H.. AU - Moscovici, C.. AU - Kung, H. J.. PY - 1989/1/1. Y1 - 1989/1/1. N2 - Avian leukosis virus induces erythroleukemia in chickens by proviral insertional mutation of the proto-oncogene c-erbB. The product of the insertionally activated c-erbB locus lacks the extracellular ligand-binding domain and is strictly leukemogenic. It has previously been demonstrated that the disease spectrum associated with aberrant c-erbB expression can be expanded by structural perturbation of the cytoplasmic domain of this protein. In this report, we use mutagenesis and retroviral vectors to identify specific mutations in the carboxyl-terminal domain of the insertionally activated c-erbB product that are sufficient to activate the sarcomagenic potential of this protein. ...
Its another beautiful day on the Old McDonald|farm, and having fed and watered the horses, cows, sheep, and other assorted barnyard animals, you decide...
Summary Peripheral blood lymphocytes of chickens bearing tumours induced by avian sarcoma virus can be specifically stimulated to divide by the crude culture fluids of virus-infected cells. In this communication, we show that relevant antigenic activity apparently resides in each of the internal virus proteins p15 and p27. The ability of infectious culture fluids to be mitogenic for sensitized lymphocytes is greatly reduced following treatment with antibodies specific for either total avian myeloblastosis virus (AMV) protein or for p27.
Primers 1 and 2 were designed from the mRNA of a guinea pig BK B2 receptor (GenBank accession no. AJ003243) to amplify a 500-base pair fragment. Primers 3 and 4 were a pair of degenerate primers used to amplify a 401-base pair fragment for the guinea pig BK B1 receptor. Primers 3 and 4 were made from the conserved region between mouse BK B1 receptor (GenBank accession no. NM_007539) and rat BK B1 receptor (GenBank accession no. U66107). Amplification was done with an iCycler (Bio-Rad, Hercules, CA). PCR cycles consisted of denaturation for 1 min at 94°C, annealing at 56°C for 90 s, and extension at 72°C for 90 s. A total of 30 cycles was followed by completion of extension for 7 min at 72°C. PCR product (12 μl) was analyzed by electrophoresis on 2% agarose gel. Sequencing was done with an ABI 373XL DNA sequencer after the PCR product was purified with Qiaquick PCR purification kit (QIAGEN, Valencia, CA). RT-PCR without avian myeloblastosis virus reverse transcriptase was used as a negative ...
RT Components: 1U/mL RNase inhibitor, 0.625U/mL reverse transcriptase (avian myeloblastosis virus, Boehringer), 1microM G1 primer, 1.75mM dNTPs ...
The KOMP Repository is located at the University of California Davis and Childrens Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at [email protected], US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors [email protected] or +1-510-450-7917 ...
The KOMP Repository is located at the University of California Davis and Childrens Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at [email protected], US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors [email protected] or +1-510-450-7917 ...
In reply to your comment, or should I say link since you did not add any thoughts on the matter I would like to say that "HIV" was observed in laboratory test under artificial stress and its appearance was endogenous. There is to date no picture of this virus observed by electron microscopy in the blood of a patient whose said they have a "high viral load" . More HIV is not an exogenous virus as people who make these claims seem to suggest , but a retrovirus, it is an important difference because our DNA contains 1% of endogenous retroviruses that may under certain conditions trigger diseases ... especially as those found in AIDS. But the question is , what makes the sick cell , why are these scientists able to identify this retro virus in a test tube , but never in humans ...
Hello,. Sometime because of large data or output users set the program to execute in background process.. Once the background job is get completed, they execute the SM37 T-code to view the information, but that information is in list view,. their they does not an option like, sorting, filtering and all.. Its a program, where user are getting the same functionality, but the output will display in ALV format, there they will get the all necessary option to format the data.. Basically the program is created based on the Z* programs, so it will be execute in only for the ALV grid output data.. ...
Indicator values are prone to statistical error (the difference between an estimated value and the true value). The statistical error associated with an indicator depends on the population subgroup (e.g. the population of a county or LGD) that it refers to. Such differences in levels of statistical error can distort what we see in maps and charts. They can make some relationships involving indicators and attributes appear "real" (practically meaningful or statistically significant) when they are in fact spurious; other relationships that are "real" can be masked. These differences in statistical error can even distort the shape of plots or the colour patterns we see in maps. For example, ...
Indicator values are prone to statistical error (the difference between an estimated value and the true value). The statistical error associated with an indicator depends on the population subgroup (e.g. the population of a county or LGD) that it refers to. Such differences in levels of statistical error can distort what we see in maps and charts. They can make some relationships involving indicators and attributes appear "real" (practically meaningful or statistically significant) when they are in fact spurious; other relationships that are "real" can be masked. These differences in statistical error can even distort the shape of plots or the colour patterns we see in maps. For example, ...
Bovine Leukosis is a disease caused by the Bovine Leukosis virus (BLV). This is a blood borne disease that dwells in the lymphocytes (white blood cells) in cattle. Only 5% of infected animals will exhibit the clinical symptoms of developing tumors in lymphatic tissue. The prevalence ofleukosis is wide spread. It is fairly common to find herds with a prevalence of 80-90%, however not very common to find herds that are completely free of leukosis. According to the NAHMS 96 study, 88.5% of dairy herds and 38.7% of beef herds are infected. Transmission occurs by the transfer of bodily fluids that contain infected white cells (blood, colostrum, milk). Anything from reusing without sanitizing contaminated needles, syringes, breeding sleeves, dehorners, or balling guns can transmit leukosis. Transmission can also occur through colostrum or to a fetus in utero. ...
Rosok, Mae Joanne, "Dissociation and isolation of the subunits of avian myeloblastosis virus RNA-directed DNA polymerase" (1977). Graduate Student Theses, Dissertations, & Professional Papers. 6828 ...
hypothetical protein, transcription factor protein, A306_09622, anon-WO03040301.171, avian myelocytomatosis viral oncogene homolog, avian myelocytomatosis viral (v-myc) oncogene homolog, bHLHe39, bHLHe57, cellular myelocytomatosis oncogene, CG10798 gene product from transcript CG10798-RB, CG10798-PA, CG10798-PB, class E basic helix-loop-helix protein 39, cmyc, c-MYC, c-myc20, c-Myc-a, c-Myc-b, c-myc-like protein, c-myc proto-oncogene, diminuitive, diminutive, DM, dm/dMyc, Dmel_CG10798, dm/myc, d-myc, dMYC, dmyc1, EG:BACN5I9.1, EGK_19271, lethal (1) G0354, lethal (1) G0359, MDA_GLEAN10014535, mMyc, MRTL, Myc2, myc-a, myc-b, MYCC, Myc-PA, Myc-PB, myc proto-oncogene protein, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, N303_07797, N307_12984, N309_06569, Niard, Nird, oncoprotein myc, PAL_GLEAN10003365, Proto-oncogene c-Myc, RNCMYC, transcription factor Myc, transcription factor p64, TREES_T100017263, uncharacterized ...
The avian myeloblastosis virus (AMV) is an alpha retrovirus responsible for acute myeloblastic leukemia (AML) when injected in ovo, or in newly hatched chickens [10]. Early in vitro dose response experiments indicated that the production of virion with leukemogenic potential required a double infection with AMV and a helper virus [11]. The AMV strains that are used and commercially available, are derived from the orignal BAI strain A purified from chicken leukemic plasma [12]. Leukemic plasma containing the BAI strain has been widely distributed for many years by Life Sciences Inc., in Florida which has been the official provider of national agencies in the USA. The Standard AMV-S BAI strain is a complex mixture of viruses that also includes two helper viruses in addition to AMV. The helper viruses Myeoloblastosis Associated Virus (MAV) contained in AMV-S belong to two different serological subgoups (type1 and type2, also called A and B). Both of them are oncogenic [13].. Both MAV-1 and MAV-2 ...
ERG antibody, Internal (v-ets avian erythroblastosis virus E26 oncogene homolog) for WB. Anti-ERG pAb (GTX77743) is tested in Human samples. 100% Ab-Assurance.
A testi és szellemi egészség szempontjából fontos a megfelelő éjszakai alvás. Az óra segítségével nyomon követheti az alvását, és figyelheti, hogy átlagosan hány órát alszik.. Ha az órát alvás közben is viseli, a Suunto Spartan Trainer Wrist HR a gyorsulásmérő adatai alapján nyomon követi az alvását. Amikor lefekszik, az órát leteheti az ágy mellé, de javasoljuk, hogy hagyja a karján, mivel így pontosabb adatokat kap az alvásáról.. Az alvás nyomon követéséhez: ...
Glynn, J P.; Halpern, B L.; and Fefer, A, "An immunochemotherapeutic system for the treatment of a transplanted moloney virus-induced lymphoma in mice." (1969). Subject Strain Bibliography 1969. 913 ...
Terms Related to the Moving Wall Fixed walls: Journals with no new volumes being added to the archive. During an 8-year period, we retrospectively collected data on all travelers hospitalized in our department for a CMI occurring during travel or in the month after their return. During an 8‐year period, we retrospectively collected data on all travelers hospitalized in our department for a CMI occurring during travel or in the month after their return. The sensitivity and versatility of this technique (immunofixation can be applied to the detection of any antigen) should permit its extension to other biological fluids with a low protein content. Exogenous viruses including bacteriophage and human herpes viruses-4, -5 and -6 were detected variably in autopsied brains from both clinical groups. This case highlights the challenges of early recognition, accurate diagnosis, appropriate treatment and follow-up of such patients. A small number of children have CP as the result of brain damage in the ...
n miben szokott aludni? T len pizsam ban, ny ron h l ingben vagy als nadr gban? B rmelyik legyen is a v lasz, tudnia kell, hogy rosszul teszi. me hat meglep ok, ami rt rdemes lenne meztelen l aludnia.
Здравсвуйте пользователи форума amv.at.ua, вчера пользователь под ником Olechkalype просила меня выложить супермодные новинки Компьютерные аксессуары/Графические планшеты в 2014, а так же сотовые бренда Intuos Pro Special Ed., так вот наконецто нашла время для этого, админы прошу не удалять, а перенести в соответствующий раздел, если я ошиблась например Компьютерные аксессуары/Графические планшеты ))) всех обнимаю ...
Пожалуй, самым разочаровывающим итогом 2013 года стало сползание в экономический застой. На протяжении года снижались как темпы роста промышленности, так и ВВП. Если в начале года еще казалось, что экономика вот-вот разгонится и из состояния «технической рецессии» войдет в фазу роста, то уже весной тональность заявлений финансовых властей смен ...
Vendredi 22 mars 2013 à 11h30 , Amélie Peres, ENS Paris. Titre : Etude de lévolution fonctionnelle des génomes ancestraux de vertébrés par duplication de gènes. Résumé Létude scientifique des processus biologiques sappuie généralement sur lobservation de résultats expérimentaux réalisés sur des modèles vivants. Cette évidence masque le fait que lensemble des organismes vivants est le fruit de centaines de millions dannées dévolution qui elles sont inaccessibles aux expériences, car situées dans le passé. Pour contribuer à rendre à la biologie cette dimension historique, notre laboratoire a entrepris de reconstruire une succession de génomes ancestraux, chez les vertébrés. Ici, nous exploitons à grande échelle les reconstitutions de génomes de vertébrés, afin de mettre en évidence, quantifier et dater les duplications de gènes au sein de différentes lignées de vertébrés. Ces duplications, en autorisant un relachement de la pression de sélection, ...
Looking for online definition of leukosis-sarcoma neoplastic diseases in the Medical Dictionary? leukosis-sarcoma neoplastic diseases explanation free. What is leukosis-sarcoma neoplastic diseases? Meaning of leukosis-sarcoma neoplastic diseases medical term. What does leukosis-sarcoma neoplastic diseases mean?
2Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4472 USA. Wnt1 signaling has been implicated as one factor involved in neural crest-derived melanocyte (NC-M) development. Mice deficient for both Wnt1 and Wnt3a have a marked deficiency in trunk neural crest derivatives including NC-Ms (1). We have used cell lineage-directed gene targeting of Wnt signaling genes to examine the effects of Wnt signaling in mouse neural crest development. Gene expression was directed to cell-lineages by infection with subgroup A avian leukosis virus vectors (RCAS) (2) in lines of transgenic mice that express the retrovirus receptor tv-a (2). Transgenic mice with tva in either nestin expressing neural precuror cells (line Ntva) or dopachrome tautomerase (DCT) expressing melanoblasts (line DCTtva) were analyzed. We over-stimulated Wnt signaling in two ways: directed gene transfer of Wnt1 to Ntva+ cells and transfer of b-catenin to DCTtva+ NC-M precursor ...
Cobalt increases the red cell mass in both man and animals by increasing the production of erythropoietin. Since meat-type chickens can develop pulmonary hypertension from increased erythropoiesis and polycythaemia, two trials were conducted to inves
Looking for Erythroblastosis faetalis? Find out information about Erythroblastosis faetalis. a disease manifested at birth or shortly thereafter and generally caused by incompatibility of the mothers blood with that of the fetus with respect to the... Explanation of Erythroblastosis faetalis
The diversity and polymorphisms in the ToMV population present in one ToMV-positive plant per genotype was further assessed. Total RNAs were isolated from the upper leaf of plants at 21 and 48 d.p.i. The complete ToMV ORF4 sequence was amplified using a two-step reverse-transcriptase polymerase chain reaction (RT-PCR) protocol. The first-strand cDNA was synthesized by reverse transcription of total RNAs using random hexamer primers and the Avian myeloblastosis virus reverse transcriptase (Promega Corp., Madison, WI, USA). A 480-bp fragment (corresponding to positions 5703-6182 of the complete ToMV reference sequence, NC_002692) was amplified using primer pair ToMV-F (5′-ATGTCTTACTCAATCACTTC-3′, sense) and ToMV-R (5′-TTAAGATGCAGGTGCAGAGG-3′, antisense) and the TaKaRa LA Taq polymerase (TaKaRa, Bio Inc., Shiga, Japan). PCR amplification was performed under the following cycling conditions: initial denaturation at 94°C for 5 min; 25 cycles of 94°C for 45 s, 54°C for 30 s, and 72°C for ...
Apffel, C A. and Peters, J H., "Successful heterotransplantation of l1210 mouse leukosis into un- treated adult hamsters. Abstr." (1968). Subject Strain Bibliography 1968. 45 ...
Compare v-myb myeloblastosis viral oncogene homolog (avian)-like 2 ELISA Kits from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more.
Looking for erythroblastoses? Find out information about erythroblastoses. The abnormal presence of erythroblasts in the blood. A virus disease of birds; considered to be part of the avian leukosis complex in which there is an... Explanation of erythroblastoses
During the late 1960s and early 1970s, cell tumor biology researchers determined that synthetic RNA and feline leukaemia virus (FELV) "template" added to "human type C" viruses--those associated with cancers of the lymph nodes increased the rate of DNA production (and subsequent provirus and virus reproduction) as much as thirty times.(1) Such hybrid viruses, these researchers reported, may cause many cancers besides leukaemias and lymphomas, including sarcomas. Other NCI and Litton Bionetics teams reported modifying the fortieth discovered simian virus (SV40) by infusing it with nucleic acids from other species including FELV RNA, avian (i.e., chicken) myeloblastosis virus (AMV) RNA, associated with leukemia and sarcoma development, and mouse sarcoma RNA to: 1) make them carcinogenic, 2) prompt extreme immunosuppression in primates,(2,4,11) and 3) study RNA-dependent DNA polymerase (i.e., reverse transcriptase) and its relationship to human carcinogenesis,(6,11-14) For example, early work in ...
An oncogenic virus (or oncovirus) is a virus that causes cancer. These include HIV, HPV (Human Papilloma Viruses), herpes viruses, hepatitis B and C viruses, Epstein Barr Virus and retroviruses. In the case of HPV and hepatitis, there are vaccines available to prevent infection with these viruses.
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The proto- oncogene c- erbB- 1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v- erbB which was isolated from an avian erythroblastosis virus ( AEV) where it was contained as a fragment of the chicken c- ErbB- 1 gene lacking the amino- terminal ligand- binding domain. Overexpression of erbB- 1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c- erbB- 1 gene is located in the chromosomal region 7p14 and 7p12 ...
Improved meat quality and greater muscle yield are highly sought after in high-quality chicken breeding programs. Past studies indicated that polymorphisms of the Perilipin gene (PLIN1) are highly associated with adiposity in mammals and are potential molecular markers for improving meat quality and carcass traits in chickens. In the present study, we screened single nucleotide polymorphisms (SNPs) in all exons of the PLIN1 gene with a direct sequencing method in six populations with different genetic backgrounds (total 240 individuals). We evaluated the association between the polymorphisms and carcass and meat quality traits. We identified three SNPs, located on the 5′ flanking region and exon 1 of PLIN1 on chromosome 10 (rs315831750, rs313726543, and rs80724063, respectively). Eight main haplotypes were constructed based on these SNPs. We calculated the allelic and genotypic frequencies, and genetic diversity parameters of the three SNPs. The polymorphism information content (PIC) ranged ...
At the first baby, there are no antibodies against Rh+, while birth, blood of the baby and the mother mixes and there are some antibodies produced, And those antibodies make the second baby die or born with some abnormalities. IgG can pass through placenta. Actually erythroblastosis fetalis can also be defined as the lysis of fetal RBCs by maternal IgGs ...
Erythroblastosis fetalis occurs due to Rh incompatibility between the mother and the fetus, resulting in severe anemia and sometimes death of the fetus.
Over the last 60 yr, the selection of economically important traits has been the main focus of breeding programs and significant genetic improvements have been achieved thus far (Dong et al. 2015). Genetic selection for an enhanced growth rate in meat-type chickens (Gallus gallus domesticus) is usually accompanied by excessive adiposity that has a negative impact on both feed efficiency and carcass quality (Resnyk et al. 2015). Genetic improvement of abdominal fat by standard selection has been minimal for two reasons: (1) the intensity of selection has declined because of the difficulty and cost to measure these phenotypes, and (2) genetic evaluations have been less accurate because they are based on information from relatives only (Demeure et al. 2013). Exploration of the molecular regulatory mechanisms of fat deposition in broilers is beneficial for optimal breeding.. Many studies have been conducted to analyze the mechanisms of adipogenesis in the chicken at the genome-wide mRNA expression ...
A survey of Czech regions saw the capital still on top, Moving to a new country is an exciting process! Prague.TVs relocation section offers expats all the information you need to make your move to Prague as smooth as possible.
MYB overexpression lysate, 0.1 mg. Transient overexpression lysate of v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2
Looking for online definition of oncornavirus in the Medical Dictionary? oncornavirus explanation free. What is oncornavirus? Meaning of oncornavirus medical term. What does oncornavirus mean?
DDC classification: 1604,T Dissertation note: Now a days pets, dogs & cats form an important part of society and their health care have gain much popularity among owners. The hazardous radiations, along with other ailments cause different cancers in them which are the most fatal diseases. This increase in cancer prevalence is also related to animals living to increasingly older ages due to better nutrition, vaccination and health care provided to them. In order to provide proper treatment and care to these animal cancer patients, it is important to gather knowledge about the genes involve in causing them. There are many genes which regulate the cell cycle progression, cell proliferation and cell differentiation. Here in this study we have tried to understand this dreadful disease at molecular level. And hoping the knowledge gain through this would help in providing better treatment in future, not only to pets but also to humans. Dogs and humans share anatomical and physiological similarities, ...
We are proposing to amend the National Poultry Improvement Plan (NPIP, the Plan) and its auxiliary provisions by removing the descriptions of specific tests and sanitation procedures from the regulations. Instead, we would require tests to be performed and sanitation to be maintained in a manner approved by the Administrator. Approved procedures would be listed in an NPIP Program Standards document, which we would make available on the NPIP Web site. In addition, we are proposing to establish new compartment classifications for defined subpopulations of primary breeding turkeys, primary egg-type chickens, and primary meat-type chickens. We would also provide new or modified sampling and testing procedures for Plan participants and participating flocks. The proposed changes were voted on and approved by the voting delegates at the Plan's 2010 and 2012 National Plan Conferences. These changes would streamline the provisions of the Plan, keep those provisions current with changes in the ...
Citation: N/A Interpretive Summary: Technical Abstract: The effect of continuous vs pulsatile cGH administration on tissue IGF-1 protein and IGF-1 mRNA levels were examined in 8 wk old meat-type chickens. Birds were infused via infusion pumps with either cGH or saline. In both regimes the birds received 123 ug/kg bwt/day. IGF-1 protein concentration (pg/mg protein) were determined by RIA and the relative levels of IGF-1 mRNA by a solution hybridization nuclease protection assay in liver, kidney, spleen, heart, muscle (gastrocnemius and pectoralis major) and growth plate cartilage. Continuous infusion elicited a two fold increase in IGF-1 concentrations in the kidney, while all other tissue concentrations were not altered. Pulsatile infusion caused a two-fold increase in IGF-1 concentrations in the liver, gastrocnemius and pectoralis muscles. IGF-1 levels in other tissues surveyed remained unchanged. With continuous infusion there was a 2-fold increase in the levels of IGF-1 mRNA in the liver and ...
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Hi! My chick is about 3 weeks old and I was wondering if anyone could help identify what type of chicken he is, along with the gender? When we got him, he was in a box with a bunch of white leghorn chickens but he was the only tan one. They said he was a leghorn but I wasnt sure if there was a ...
or... what a lot of luck and a fantastic medical care system can do for you! , If youre planning on staying in Prague for any length of time, it makes sense to familiarize yourself with the healthcare options available in the city. Nothing is more important than your health!
Tento oživující tělový peeling s rozemletou pemzou a bambusovým stvolem probudí tělo i duši aromatickou vůní jedle, borovice, šalvěje a hřebíčku. Ideální pro hloubkovou očistu pleti nebo před holením či depilací voskem, aby se zabránilo zarůstání chloupků.
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Define erythroblastosis fetalis. erythroblastosis fetalis synonyms, erythroblastosis fetalis pronunciation, erythroblastosis fetalis translation, English dictionary definition of erythroblastosis fetalis. n. A severe hemolytic disease of a fetus or newborn infant caused by the production of maternal antibodies against the fetal red blood cells, usually...
The effect of negative stain, freeze-fracture, and thin-sectioning procedures on the size of several oncornaviruses has been determined. After negative staining, the average outer dimensions measured over several experiments for the C-type avian viruses, avian myeloblastosis virus (AMV) and Rous sarcoma virus, Prague strain, were about 1370 and 1340 Å, respectively. These values were substantially smaller than the outer dimensions of the C-type murine viruses, Friend leukemia virus (FLV), namely, 1470 Å, and Moloney leukemia virus, namely, 1460 Å. The avian viruses were similar in size to the B-type murine virus, mouse mammary tumor virus, which measured about 1290 Å. All experimental values were obtained after glutaraldehyde (1.5%) fixation and uranyl acetate (2%, pH 4.2) staining. Other negative stains, such as sodium phosphotungstate (1%, pH 6.6), lead to disruption of the outer envelope and a concomitant diminution in size. Freeze-fractured preparations of AMV showed particles with or ...
Chicken erythroblasts transformed with avian erythroblastosis virus or S13 virus provide suitable model systems with which to analyze the maturation of immature erythroblasts into erythrocytes. The transformed cells are blocked in differentiation at around the colony-forming unit-erythroid stage of development but can be induced to differentiate in vitro. Analysis of the expression and assembly of components of the membrane skeleton indicates that these cells simultaneously synthesize alpha-spectrin, beta-spectrin, ankyrin, and protein 4.1 at levels that are comparable to those of mature erythroblasts. However, they do not express any detectable amounts of anion transporter. The peripheral membrane skeleton components assemble transiently and are subsequently rapidly catabolized, resulting in 20-40-fold lower steady-state levels than are found in maturing erythrocytes. Upon spontaneous or chemically induced terminal differentiation of these cells expression of the anion transporter is initiated ...
Menu, hours, photos, and more for Leghorn Chicken located at 959 N Western Ave, Chicago, IL, 60622-4619, offering Dinner, Chicken, Sandwiches and Lunch Specials. View the menu for Leghorn Chicken on MenuPages and find your next meal ...
Abstract: Contents of scvalene, sterols and their derivatives were studied in lymphoid tissues as well as in liver and kidney tissues of normal rats and the animals with Shvetz experimental leukosis. Amount of cholesterol and of its precursor scvalene was distinctly decreased simultaneously with an increase in total content of nonsaponified substances in thymus, spleen, bone marrow and liver tissue of rats with experimental leukosis. Scvalene was increased in kidney tissue. Simultaneous accumulation of hydroxycholesterol derivatives, among which 7-beta-hydroxycholesterol was identified, was observed in these tissues under conditions of leukosis. Role of cholesterol hydroxyderivatives in biosynthesis of sterols is discussed ...
PRIMARY OBJECTIVES:. I. To prospectively analyze the factors that are currently used for risk-group assignment (v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog [MYCN] copy number by fluorescent in situ hybridization [FISH], deoxyribonucleic acid [DNA] content by flow cytometry, and tumor histology using the International Neuroblastoma Pathologic Classification System) in neuroblastoma tumors at the time of diagnosis.. II. To maintain a reference bank containing clinically and genetically characterized frozen tumor tissue, tumor DNA and ribonucleic acid (RNA), histology slides and paraffin blocks, neuroblastoma-derived cell lines, patient serum and paired normal DNA obtained at the time of diagnosis, at the time of second-look surgery and at the time of relapse for future research studies.. III. To prospectively analyze 1p, 11q, 14q and 17q allelic status, MYCN copy number by quantitative polymerase chain reaction (PCR); and the expression pattern of neurotrophin-related ...
Austin, John Holcombe, "Erythroblastosis fetalis: Pathogenesis and prognosis. A study of clinical obstetrical data" (1965). Yale Medicine Thesis Digital Library. 2367 ...
One possible strategy to optimize breeding programmes in terms of feed costs is selecting animals based on their genetic performance over protein levels (PL). A genotype and environment (G×E) interaction in which the gradual environmental changes are represented by the respective PL is such a...
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This app supports the AMI Prague Conference at the Hilton Prague 17th-18th February 2017. It offers many features including: · Personalised agendas· Hotel information· Meeting bookin
The news about cancer to which reputable specialists pay attention is not wild announcements of a sure cure for all types of the disease, but sober reports of cancer facts dug up in laboratories and...
Read the U Krále Karla, Prague hotel review on Telegraph Travel. See great photos, full ratings, facilities, expert advice and book the best hotel deals.
Fly from Prague to Tunis in April 2018 from as little as CZK 3229* ✈✈✈ PRG-TUN in April 2018 ✓Eurowings - book here at eurowings.com ✓ No hidden costs ✓
Ujerumani imefanikiwa kusonga mbele kugombea nafasi katika mashindano ya kandanda ya Ubingwa wa Ulaya mwaka 2008 baada ya kuikandika Jamhuri ya Czech mabao 2-1 mjini Prague.Mabao yote mawili yalitiwa na Kevin Kuranyi.Timu ya Ujerumani haikushindwa katika kundi lake,baada ya michezo mitano na sasa inaongoza kwa pointi tatu katika kundi D.. ...
ZTE had a pretty strong presence at MWC 2015 and brought a few phones to the venue. Few among them were actually new. So we decided to go ahead and skip...
La Bodeguita Del Medio Praga - bar de cócteles y un restaurante cubano de música. Especialidades de América Latina y de la cocina internacional. Platos tradicionales criollos.
A bárdok remegve reménykednek, hogy nem megy el a Nouvelle Secheux (Dezheuxiana, a Misishayaux-mente) eisteddfodra OlTiby a Sajó-deltáből, ahol lassan folyik a víz és lassan jön a szó…... ...
LOS ANGELES - The Laboratory for Developmental Genetics at USC has confirmed cytomegalovirus (CMV) as a cause of the most common salivary gland cancers. CMV joins a group of fewer than 10 identified oncoviruses - cancer-causing viruses - including HPV.. The findings, published online in the journal Experimental and Molecular Pathology over the weekend, are the latest in a series of studies by USC researchers that together demonstrate CMVs role as an oncovirus, a virus that can either trigger cancer in healthy cells or exploit mutant cell weaknesses to enhance tumor formation. Lead author Michael Melnick, professor of developmental genetics in the Ostrow School of Dentistry of USC and Co-Director of the Laboratory for Developmental Genetics, said the conclusion that CMV is an oncovirus came after rigorous study of both human salivary gland tumors and salivary glands of postnatal mice. CMVs classification as an oncovirus has important implications for human health. The virus, which has an ...
Abstract: Amount of cholesterol was distinctly decreased but content of scvalene, lanosterol, 7-dehydrocholesterol and 7-beta-hydroxycholesterol--increased in erythrocyte membranes of rats with Shvetz experimental leukosis. At the same time, osmotic stability of erythrocytes and a pattern of acidic erythrogramms were altered. After UV irradiation of rats amount of cholesterol was increased as well as other unidentified substances appeared in erythrocyte membranes. These alterations appear to be one of factors responsible for development of body resistance to leukosis ...
Retrovirus- associated DNA sequences ( v- myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto- oncogene c- myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22- 23 on the short arm of chromosome 6. This is the point of break in translocations involved in T- cell acute lymphatic leukemia and in some ovarian cancers and melanomas. ( From Ibelgaufts, Dictionary of Cytokines, 1995 ...
In the 1990s, scientists in Kenya noticed an alarming development. The traditional African leafy vegetables (ALV) they had eaten as children were rapidly disappearing from farmers fields and peoples tables. ALVs contain vitamins and minerals that are lacking in many of the major staple foods consumed in sub-Saharan Africa but the vegetables had been neglected by researchers, growers and consumers for decades. Many people considered ALVs to be inferior to, and less fashionable than, introduced vegetables such as cabbage and kale. This dietary shift was not only placing the genetic diversity of these vegetables at risk, but also the nutrition security of vulnerable groups. ...
As the year 2011 is almost over, lets go through a quick overview of the dramas that were released this year. This year dramas, as recorded, have the lowest ratings comparing to the previous years. I blame TVB for this as it chose the wrong series to air. We see the same faces on screen all year round!! I also blame the scripts, and as people are saying how the scripts are getting worse and worse every year, yes I can see that. This year, there are also many good artistes leaving TVB, including my favorite Charmaine:( To those who left, I wish them good luck. To TVB, I hope it can make better drama next year as there are now competing TV stations in HK. Now back to 2011 series, I can say that I watch almost all of them. Yes, almost! Some were too boring or illogical to capture my attention so I skipped them. And I also skipped sitcoms and mini series. ...
Evaluation of genetic variation within and between different chicken lines by DNA fingerprinting. Genetic similarity using DNA fingerprinting in cattle to determine relationship coefficient
Prague has fifteen numbered districts: Praha 1 through to Praha 15. Praha 1 is the oldest part of the city, and has by far the densest number of attractions. It can be further subdivided into these quarters: *Castle (Hradčany) -- the highest point in Prague *Lesser Town (Malá Strana) -- the settlement around the castle *Old Town (Staré Město) -- the nucleus of the right bank *New Town (Nove Město) -- the fourteenth century district south of Old Town *Jewish Town (Josefov) -- the old Jewish ghetto
Boscolo Prague, Autograph Collection: The swimming pool was awesome as well - See 2,805 traveller reviews, 1,364 candid photos, and great deals for Boscolo Prague, Autograph Collection at TripAdvisor.
... : Prague, aka Alessandro Viccaro, musica alti_sonante e che crogiola nel dopo sbornia Pavement e Pedro the Lion, pubblica sulla webzine Movimenta un Ep ...
Looking for the definition of ASLV? Find out what is the full meaning of ASLV on Abbreviations.com! Augumented Satellite Launch Vehicle is one option -- get in to view more @ The Webs largest and most authoritative acronyms and abbreviations resource.
A tiny Lesser Mouse-Deer was born on November 1 at the Prague Zoo. This species is the smallest of all known hoofed mammals. Adults have bodies about the same size as rabbits, have legs the size of pencils, and weigh...
A tiny Lesser Mouse-Deer was born on November 1 at the Prague Zoo. This species is the smallest of all known hoofed mammals. Adults have bodies about the same size as rabbits, have legs the size of pencils, and weigh...
Un centre de R&D au sein de la plateforme Technocampus CompositesCest en 2009, quaux côtés dAirbus et dEADS IW, au sein du GIE CMII, le Cetim sest installé dans Technocampus Composites (alors EMC2), partageant ainsi lambition de créer un pôle de référence et de développer le tissu industriel, notamment autour des matériaux composites et des structures multimatériaux. Cette dynamique a été renforcée avec la création en 2011 de lIRT Jules Verne.
The sequence of the human epidermal growth factor (EGF) receptor shows great homology with the avian erythroblastosis virus v-erb B oncogene, raising the possibility that the receptor gene is identical to the c-erb B protooncogene. Human A431 epidermoid carcinoma cells, which have an unusually high number of EGF receptors, were examined to determine whether elevated EGF receptor levels correlate with gene amplification. Southern blots of genomic DNAs from A431 and other human cell lines were probed with either a v-erb B gene fragment or a human EGF receptor complementary DNA clone (pE7), previously isolated from an A431 complementary DNA library. When either probe was used to analyze Eco RI- or Hind III-generated DNA fragments, EGF receptor DNA sequences were amplified about 30-fold in A431. Differences in the banding pattern of A431 DNA fragments relative to normal fibroblast DNA indicate the occurrence of a rearrangement in the region of the receptor gene. Furthermore, A431 cells contain a ...
The Naming of Prague Salt by Eben van Tonder 8 May 2016 For a booklet version of this article, visit: https://thenamingofpraguesalt.pressbooks.com/ PDF version: The Naming of Prague Salt INDEX INTRODUCTION MEAT CURING: 1600 - 1910 QUESTIONS ABOUT THE ORIGIN OF PRAGUE SALT EARLY EXPERIMENTS WITH SODIUM NITRITE EARLY PUBLIC PERCEPTION ABOUT NITRITE PRAGUE 1800 - 1920…

Rapid detection of the common avian leukosis virus subgroups by real-time loop-mediated isothermal amplification | Virology...Rapid detection of the common avian leukosis virus subgroups by real-time loop-mediated isothermal amplification | Virology...

The results verify that the LAMP method was more sensitive than the conventional PCR and virus isolation method. In conclusion ... assay were developed and compared with PCR and virus isolation methods. The results from specificity of the LAMP assay showed ... E and J are the major subgroups of avian leukosis virus (ALV) infecting chickens. ALV infection has become endemic in China and ... Avian Pathol. 2009;38(6):443-8.Google Scholar. *. Zavala G, Cheng S. Detection and characterization of avian leukosis virus in ...
more infohttps://virologyj.biomedcentral.com/articles/10.1186/s12985-015-0430-1

Incidence of avian leukosis virus infection in broiler stocks...Incidence of avian leukosis virus infection in broiler stocks...

Twenty-eight broiler breeder flocks were tested for avian leukosi ... Incidence of avian leukosis virus infection in broiler stocks ... Incidence of avian leukosis virus infection in broiler stocks and its effect on early growth.. Authors * Crittenden, L B ... Twenty-eight broiler breeder flocks were tested for avian leukosis virus (ALV) group-specific (gs) antigen shedding into the ... Progeny of positive dams or chicks having virus in their meconia weighed 1 to 3% less at 4 and 7 weeks than progeny of negative ...
more infohttps://www.mysciencework.com/publication/show/incidence-avian-leukosis-virus-infection-broiler-stocks-its-effect-early-growth-d127ef90

Creation and expression of myristylated forms of Rous sarcoma virus Gag protein in mammalian cells<...Creation and expression of myristylated forms of Rous sarcoma virus Gag protein in mammalian cells<...

Rous sarcoma virus (RSV), a member of the avian sarcoma and leukosis family of retroviruses, has long been known to be capable ... N2 - Rous sarcoma virus (RSV), a member of the avian sarcoma and leukosis family of retroviruses, has long been known to be ... AB - Rous sarcoma virus (RSV), a member of the avian sarcoma and leukosis family of retroviruses, has long been known to be ... abstract = "Rous sarcoma virus (RSV), a member of the avian sarcoma and leukosis family of retroviruses, has long been known to ...
more infohttps://pennstate.pure.elsevier.com/en/publications/creation-and-expression-of-myristylated-forms-of-rous-sarcoma-vir

Reticuloendotheliosis, X-Linked disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsReticuloendotheliosis, X-Linked disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Reticuloendotheliosis virus and avian leukosis virus subgroup J synergistically increase the accumulation of exosomal miRNAs. ... Histologic findings and viral antigen distribution in natural coinfection of layer hens with subgroup J avian leukosis virus, ... Isolation and characterization of subgroup J Avian Leukosis virus associated with hemangioma in commercial Hy-Line chickens. 61 ... Epidemiological investigation of the novel genotype avian hepatitis E virus and co-infected immunosuppressive viruses in farms ...
more infohttps://www.malacards.org/card/reticuloendotheliosis_x_linked

Avian Leukosis, Lymphoid Leukosis, Leukosis/Sarkoma Group - El Sitio AvicolaAvian Leukosis, Lymphoid Leukosis, Leukosis/Sarkoma Group - El Sitio Avicola

The causative viruses are rapidly inactivated at ambient temperature and on exposure to most disinfectants. Signs. *Depression ... Avian Leukosis, Lymphoid Leukosis, Leukosis/Sarkoma Group Extracted From: A Pocket Guide to ... In lymphoid leukosis the incubation period is about 4-6 months; it may be as short as 6 weeks for some of the other ... A complex of viral diseases with various manifestations such as lymphoid leukosis, myeloblastosis (see Sero-type J), ...
more infohttp://www.elsitioavicola.com/diseaseinfo/11/avian-leukosis-lymphoid-leukosis-leukosis-sarkoma-group/

Avian sarcoma leukosis virus - WikipediaAvian sarcoma leukosis virus - Wikipedia

"Avian sarcoma and leukosis virus-receptor interactions: from classical genetics to novel insights into virus-cell membrane ... Avian sarcoma leukosis virus is characterized by a wide range of tumors, the most common of which are lymphomas. Lymphoid ... Avian sarcoma leukosis virus (ASLV) is an endogenous retrovirus that infects and can lead to cancer in chickens; experimentally ... ISBN 978-1-118-71973-2. Riddell, C. (May-June 1999). "The current problem with Avian Leukosis J Virus". California Poultry ...
more infohttps://en.wikipedia.org/wiki/Avian_sarcoma_leukosis_virus

The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV of...The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV of...

The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV of ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/4287699?dopt=Abstract

Occupational exposure to poultry and prevalence of antibodies against Mareks disease virus and avian leukosis retroviruses. |...Occupational exposure to poultry and prevalence of antibodies against Marek's disease virus and avian leukosis retroviruses. |...

Occupational exposure to poultry and prevalence of antibodies against Mareks disease virus and avian leukosis retroviruses. ... Occupational exposure to poultry and prevalence of antibodies against Mareks disease virus and avian leukosis retroviruses. ... Occupational exposure to poultry and prevalence of antibodies against Mareks disease virus and avian leukosis retroviruses. ...
more infohttps://oem.bmj.com/content/53/6/403.info

Integration Targeting by Avian Sarcoma-Leukosis Virus and Human Immunodeficiency Virus in the Chicken Genome | Journal of...Integration Targeting by Avian Sarcoma-Leukosis Virus and Human Immunodeficiency Virus in the Chicken Genome | Journal of...

Virus-Cell Interactions. Integration Targeting by Avian Sarcoma-Leukosis Virus and Human Immunodeficiency Virus in the Chicken ... Integration Targeting by Avian Sarcoma-Leukosis Virus and Human Immunodeficiency Virus in the Chicken Genome ... Integration Targeting by Avian Sarcoma-Leukosis Virus and Human Immunodeficiency Virus in the Chicken Genome ... Integration Targeting by Avian Sarcoma-Leukosis Virus and Human Immunodeficiency Virus in the Chicken Genome ...
more infohttps://jvi.asm.org/content/79/18/12035?ijkey=7074b66c315059c02f10dd021ec47022aae2d4d1&keytype2=tf_ipsecsha

Isolation and characterization of subgroup J Avian Leukosis virus associated with hemangioma in commercial Hy-Line chickens,...Isolation and characterization of subgroup J Avian Leukosis virus associated with hemangioma in commercial Hy-Line chickens,...

"Isolation and characterization of subgroup J Avian Leukosis virus associated with hemangioma in commercial Hy-Line chickens, ... Occurrence of avian leukosis virus subgroup J in commercial layer flocks in China . Avian Pathol. 33 : 13 - 17 . Google Scholar ... Occurrence of avian leukosis virus subgroup J in commercial layer flocks in China . Avian Pathol. 33 : 13 - 17 . Google Scholar ... Avian sarcoma and leukosis virus-receptor interactions: from classical genetics to novel insights into virus-cell membrane ...
more infohttps://www.deepdyve.com/lp/ou_press/isolation-and-characterization-of-subgroup-j-avian-leukosis-virus-LppSAwsCk7

Identification of a linear B-cell epitope on the avian leukosis virus P27 protein using monoclonal antibodies, Archives of...Identification of a linear B-cell epitope on the avian leukosis virus P27 protein using monoclonal antibodies, Archives of...

"Identification of a linear B-cell epitope on the avian leukosis virus P27 protein using monoclonal antibodies, Archives of ... Recovery of acutely transforming viruses from myeloid leukosis induced by the HPRS-103 strain of avian leukosis virus ... Avian leukosis virus (ALV) is an avian oncogenic retrovirus that can induce various clinical tumors. The capsid protein P27 is ... Isolation and some characteristics of a subgroup J-like avian leukosis virus associated with myeloid leukosis in meat-type ...
more infohttps://www.deepdyve.com/lp/springer_journal/identification-of-a-linear-b-cell-epitope-on-the-avian-leukosis-virus-6WZYR6RPIc

Conformation Change of the Loop Adenine of Avian Leukosis Virus RNA Upon Antibiotic Binding Revealed by 2-Aminopurine...Conformation Change of the Loop Adenine of Avian Leukosis Virus RNA Upon Antibiotic Binding Revealed by 2-Aminopurine...

Structural dynamics and local changes in the dimerization site of avian retroviral RNA were studied. Our task was to identify ... To this end we replaced the unpaired adenine in the hairpin loop of avian leukosis virus RNA with a fluorescent probe 2- ... Conformation Change of the Loop Adenine of Avian Leukosis Virus RNA Upon Antibiotic Binding Revealed by 2-Aminopurine ... Structural dynamics and local changes in the dimerization site of avian retroviral RNA were studied. Our task was to identify ...
more infohttp://www.jbsdonline.com/c3034/c4265/conformation-change-loop-adenine-of-avian-leukosis-virus-rna-upon-antibiotic-binding-revealed-2-aminopurine-fluorescence-p17300.html

Conformation Change of the Loop Adenine of Avian Leukosis Virus RNA Upon Antibiotic Binding Revealed by 2-Aminopurine...Conformation Change of the Loop Adenine of Avian Leukosis Virus RNA Upon Antibiotic Binding Revealed by 2-Aminopurine...

Structural dynamics and local changes in the dimerization site of avian retroviral RNA were studied. Our task was to identify ... To this end we replaced the unpaired adenine in the hairpin loop of avian leukosis virus RNA with a fluorescent probe 2- ... Conformation Change of the Loop Adenine of Avian Leukosis Virus RNA Upon Antibiotic Binding Revealed by 2-Aminopurine ... Structural dynamics and local changes in the dimerization site of avian retroviral RNA were studied. Our task was to identify ...
more infohttps://www.jbsdonline.com/conformation-change-loop-adenine-of-avian-leukosis-virus-rna-upon-antibiotic-binding-revealed-2-aminopurine-fluorescence-p17300.html

Role of basic residues in the subgroup-determining region of the subgroup A avian sarcoma and leukosis virus envelope in...Role of basic residues in the subgroup-determining region of the subgroup A avian sarcoma and leukosis virus envelope in...

Receptor specificity in avian sarcoma and leukosis viruses (ASLV) maps to the central region of the envelope surface protein, ... of the ASLV envelope sequences revealed a cluster of basic residues within hr2 that is unique to the subgroup A viruses, ... Receptor-induced conformational changes in the subgroup A avian leukosis and sarcoma virus envelope glycoprotein.. *J M Gilbert ... Receptor specificity in avian sarcoma and leukosis viruses (ASLV) maps to the central region of the envelope surface protein, ...
more infohttps://www.semanticscholar.org/paper/Role-of-basic-residues-in-the-subgroup-determining-Rong-Edinger/79740a5ff894eb6e9904933e8c50a020116d48ed

Reply to commentary by D. Elleder and J. Hejnar on the article Avian sarcoma and leukosis virus gag gene in the Anser anser...Reply to commentary by D. Elleder and J. Hejnar on the article "Avian sarcoma and leukosis virus gag gene in the Anser anser...

Actually, endogenous avian sarcoma and leukosis virus (enASLV) sequences are variable in the Galliformes birds, and geese have ... Reply to commentary by D. Elleder and J. Hejnar on the article "Avian sarcoma and leukosis virus gag gene in the Anser anser ... Actually, endogenous avian sarcoma and leukosis virus (enASLV) sequences are variable in the Galliformes birds, and geese have ... Actually, endogenous avian sarcoma and leukosis virus (enASLV) sequences are variable in the Galliformes birds, and geese have ...
more infohttps://www.geneticsmr.com/articles/5973

Frontiers | MicroRNAs in the Host Response to Viral Infections of Veterinary Importance | Veterinary ScienceFrontiers | MicroRNAs in the Host Response to Viral Infections of Veterinary Importance | Veterinary Science

Avian Leukosis Virus. Avian leukosis virus (ALV) belongs to the genus Alpharetrovirus of the Retroviridae family. This virus is ... influenza A virus (IAV); infectious bursal disease virus (IBDV); Mareks disease virus (MDV); avian leukosis virus (ALV); ... Role of gga-miR-221 and gga-miR-222 during tumour formation in chickens infected by subgroup J avian leukosis virus. Viruses ( ... Aberrant expression of liver microRNA in chickens infected with subgroup J avian leukosis virus. Virus Res (2012) 169(1):268-71 ...
more infohttps://www.frontiersin.org/articles/10.3389/fvets.2016.00086/full

Vaccine Contamination with other viruses - Avian Leukosis Virus - ClinicalNews.OrgVaccine Contamination with other viruses - Avian Leukosis Virus - ClinicalNews.Org

PMCID: PMC112645 Evidence of Avian Leukosis Virus Subgroup E and Endogenous Avian Virus in Measles and Mumps Vaccines Derived ... Evidence of Avian Leukosis Virus Subgroup E and Endogenous Avian Virus in Measles and Mumps Vaccines Derived from Chicken Cells ... Vaccine Contamination with other viruses - Avian Leukosis Virus. May 5, 2015. Vaccine 0 Comments ... Lack of evidence of endogenous avian leukosis virus and endogenous avian retrovirus transmission to measles, mumps, and rubella ...
more infohttps://clinicalnews.org/2015/05/05/vaccine-contamination-with-other-viruses-avian-leukosis-virus/?shared=email&msg=fail

ALV (ag) - Avian Leukosis Virus Antigen - BioChek, smart veterinary diagnosticsALV (ag) - Avian Leukosis Virus Antigen - BioChek, smart veterinary diagnostics

The Avian Leukosis Virus p27 Antigen test kit will determine the presence of the p27 antigen of the Avian Leukosis Virus in ... To detect antigen (P27) of Avian Leukosis Virus. Kit format:. Plates per kit: 5. Maximum sample size: 460. Run at room ... A highly specific ELISA for detection of Avian Leukosis Virus antigen, used in eradication programs. ... The Avian Leukosis Virus Antigen test kit is used for:. *Screening flocks for presence or absence of Avian Leukosis Virus ...
more infohttps://www.biochek.com/poultry-elisa/avian-leukosis-virus-antigen-test-kit/

Avian leukosis virus (ALV) infection, shedding, and tumors in maternal ALV antibody-positive and -negative chickens exposed to...Avian leukosis virus (ALV) infection, shedding, and tumors in maternal ALV antibody-positive and -negative chickens exposed to...

... negative chickens exposed to virus at hatching. , Avian diseases , 7/27/1988 ... Avian leukosis virus (ALV) infection, shedding, and tumors in maternal ALV antibody-positive and - ... Avian Dis. 1988;32(1):89-95. Chickens highly susceptible to avian leukosis virus (ALV) infection and tumors, with and without ... Avian diseases PubMedID: 2838017. Fadly AM. Avian leukosis virus (ALV) infection, shedding, and tumors in maternal ALV antibody ...
more infohttps://www.docphin.com/research/article-detail/14791987/PubMedID-2838017/Avian-leukosis-virus-ALV-infection-shedding-and-tumors-in-maternal-ALV-antibody-positive-and-negative-chickens-exposed-to-virus-at-hatching

What is Avian sarcoma leukosis virus?, Explain Avian sarcoma leukosis virus - Virology HubWhat is Avian sarcoma leukosis virus?, Explain Avian sarcoma leukosis virus - Virology Hub

Avian sarcoma leukosis virus ~~~ Title: What is Avian sarcoma leukosis virus?, Explain Avian sarcoma leukosis virus Created on ... What is Avian sarcoma leukosis virus?, Explain Avian sarcoma leukosis virus. by admin · April 14, 2019. ...
more infohttp://achengula.com/2019/04/14/what-is-avian-sarcoma-leukosis-virus-explain-avian-sarcoma-leukosis-virus/

Retrovirus - WikipediaRetrovirus - Wikipedia

Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ... Such viruses are either single stranded RNA (e.g. HIV) or double stranded DNA (e.g. Hepatitis B virus) viruses. ... Genus Betaretrovirus; type species: Mouse mammary tumour virus. *Genus Gammaretrovirus; type species: Murine leukemia virus; ... "Virus Taxonomy: 2018b Release" (html). International Committee on Taxonomy of Viruses (ICTV). March 2019. Retrieved 16 March ...
more infohttps://en.wikipedia.org/wiki/SsRNA-RT_virus

Retrovirus - WikipediaRetrovirus - Wikipedia

Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ... Genus Betaretrovirus; type species: Mouse mammary tumour virus. *Genus Gammaretrovirus; type species: Murine leukemia virus; ... "Virus Taxonomy: 2018b Release" (html). International Committee on Taxonomy of Viruses (ICTV). March 2019. Retrieved 16 March ... Group VII viruses[edit]. Both families in Group VII have DNA genomes contained within the invading virus particles. The DNA ...
more infohttps://en.wikipedia.org/wiki/Retrovirus

Avian leukosis virus subgroup J induces its receptor--chNHE1 up-regulation | Virology Journal | Full TextAvian leukosis virus subgroup J induces its receptor--chNHE1 up-regulation | Virology Journal | Full Text

The result showed that the mRNA level of chNHE1 was up-regulated after virus shedding, especially in continuous viremic ... Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus which causes immunosuppression and neoplasia in meat-type ... From: Avian leukosis virus subgroup J induces its receptor--chNHE1 up-regulation ...
more infohttps://virologyj.biomedcentral.com/articles/10.1186/s12985-016-0517-3/tables/2

Virus-Host Interactions in the Development of Avian Leukosis Virus-Ind by Rosalinda Gram Foster"Virus-Host Interactions in the Development of Avian Leukosis Virus-Ind" by Rosalinda Gram Foster

... suggesting an atypical life cycle of the virus in the infected osteoblasts. To better understand virus-host interactions in the ... The effect of virus infection on osteoblast function was examined in the diseased bone and in osteoblast cultures. In infected ... In culture, virus infection had no apparent effect on either the proliferation or differentiation of osteoblasts. This ... It is possible that the accumulation of virus could facilitate the high levels of infection observed in the diseased bone. The ...
more infohttp://escholarship.umassmed.edu/gsbs_diss/180/

Enhanced inhibition of Avian leukosis virus subgroup J replication by multi-target miRNAs - pdf descargarEnhanced inhibition of Avian leukosis virus subgroup J replication by multi-target miRNAs - pdf descargar

Enhanced inhibition of Avian leukosis virus subgroup J replication by multi-target miRNAs. . Biblioteca virtual para leer y ... Enhanced inhibition of Avian leukosis virus subgroup J replication by multi-target miRNAs - Descarga este documento en PDF. ... ResultsIn this study, the avian leukosis virus subgroup J ALV-J proviral genome, including the gag genes, were treated as ... Enhanced inhibition of Avian leukosis virus subgroup J replication by multi-target miRNAs. ...
more infohttp://libros.duhnnae.com/2017/aug/150157863835-Enhanced-inhibition-of-Avian-leukosis-virus-subgroup-J-replication-by-multi-target-miRNAs.php
  • Twenty-eight broiler breeder flocks were tested for avian leukosis virus (ALV) group-specific (gs) antigen shedding into the albumen. (mysciencework.com)
  • A set of four specific primers was designed to target the sequences of the pol gene of ALV, and the loop-mediated isothermal amplification (LAMP) assay were developed and compared with PCR and virus isolation methods. (biomedcentral.com)
  • The results verify that the LAMP method was more sensitive than the conventional PCR and virus isolation method. (biomedcentral.com)
  • In all aspects examined, the behavior of myristylated Pr76 was identical to that of the authentic product produced in avian cells. (elsevier.com)
  • For this virus group, it is possible to compare the placement of de novo sites of integration generated experimentally to the preexisting distribution of ERVK sequences, allowing the forces dictating the accumulation of ERVs to be specified more precisely. (asm.org)
  • A set of four specific primers was designed to target the sequences of the pol gene of ALV, and the loop-mediated isothermal amplification (LAMP) assay were developed and compared with PCR and virus isolation methods. (biomedcentral.com)
  • The avian leukosis virus sequences found in the measles vaccine are in intact virions, as DNA treatment of the vaccines did not prevent their detection by polymerase chain reaction (PCR). (clinicalnews.org)
  • A detailed understanding of retroviral cell entry may lead to the discovery of ways in which to block the viruses from entering cells. (wikipedia.org)
  • Structural dynamics and local changes in the dimerization site of avian retroviral RNA were studied. (jbsdonline.com)
  • Hence, it is an enveloped virus with a condensed, central core, and has barely visible envelope spikes, or proteins. (wikipedia.org)
  • A retrovirus is a type of RNA virus that inserts a copy of its genome into the DNA of a host cell that it invades, thus changing the genome of that cell. (wikipedia.org)
  • Once inside the host cell's cytoplasm , the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus retro (backwards). (wikipedia.org)
  • ResultsIn this study, the avian leukosis virus subgroup J ALV-J proviral genome, including the gag genes, were treated as targets for RNAi. (duhnnae.com)
  • The results verify that the LAMP method was more sensitive than the conventional PCR and virus isolation method. (biomedcentral.com)
  • Studies of several thousand sites of human immunodeficiency virus (HIV) integration in human cells indicated that transcription units (TUs) are favored for integration, and comparison to transcriptional profiles from target cells indicates that active TUs are particularly favored ( 19 , 26 , 31 ). (asm.org)
  • Lymphoid leukosis is the most common form of this disease and with typical presentation of gradual onset, persistent low mortality, and neoplasia of the bursa. (wikipedia.org)
  • Because both porcine circovirus 1 and 2 are common in healthy pigs, it's likely that humans are frequently exposed to these viruses by eating pork or when workers at swine farms inhale pig feces. (clinicalnews.org)
  • Increase of 1.3 per cent in the total number of avian diagnostic submissions to AHVLA and SAC during Q3-2013 compared with Q3-2012. (thepoultrysite.com)
  • Lymphoid leukosis was eradicated in primary breeders in the 1980s and 1990s which dramatically reduced the incidence of the disease in commercial laying hens. (wikipedia.org)
  • Commercial broilers are still struggling with ALV-J virus in many countries. (wikipedia.org)
  • Murine leukemia virus (MLV), in contrast, showed an integration bias in favor of CpG islands and transcription start sites ( 31 ) and a weaker preference for transcription units. (asm.org)