Avian leukosis virus
Uterine Cervical Incompetence
Incompetent UTERINE CERVIX is usually diagnosed in the second trimester of PREGNANCY. It is characterized by passive painless cervical dilation in the absence of UTERINE CONTRACTION; BLEEDING; INFECTION; and sometimes with the amniotic sac (AMNIOTIC MEMBRANE) bulging through the partially dilated cervix. Left untreated, this condition may lead to premature pregnancy loss, such as HABITUAL ABORTION.
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Herpesvirus 2, Gallid
Nucleic Acid Amplification Techniques
Sensitivity and Specificity
Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Change in the surface ANTIGEN of a microorganism. There are two different types. One is a phenomenon, especially associated with INFLUENZA VIRUSES, where they undergo spontaneous variation both as slow antigenic drift and sudden emergence of new strains (antigenic shift). The second type is when certain PARASITES, especially trypanosomes, PLASMODIUM, and BORRELIA, survive the immune response of the host by changing the surface coat (antigen switching). (From Herbert et al., The Dictionary of Immunology, 4th ed)
Bursa of Fabricius
Identification of key residues in subgroup A avian leukosis virus envelope determining receptor binding affinity and infectivity of cells expressing chicken or quail Tva receptor. (1/162)To better understand retroviral entry, we have characterized the interactions between subgroup A avian leukosis virus [ALV(A)] envelope glycoproteins and Tva, the receptor for ALV(A), that result in receptor interference. We have recently shown that soluble forms of the chicken and quail Tva receptor (sTva), expressed from genes delivered by retroviral vectors, block ALV(A) infection of cultured chicken cells ( approximately 200-fold antiviral effect) and chickens (>98% of the birds were not infected). We hypothesized that inhibition of viral replication by sTva would select virus variants with mutations in the surface glycoprotein (SU) that altered the binding affinity of the subgroup A SU for the sTva protein and/or altered the normal receptor usage of the virus. Virus propagation in the presence of quail sTva-mIgG, the quail Tva extracellular region fused to the constant region of the mouse immunoglobulin G (IgG) protein, identified viruses with three mutations in the subgroup A hr1 region of SU, E149K, Y142N, and Y142N/E149K. These mutations reduced the binding affinity of the subgroup A envelope glycoproteins for quail sTva-mIgG (32-, 324-, and 4,739-fold, respectively) but did not alter their binding affinity for chicken sTva-mIgG. The ALV(A) mutants efficiently infected cells expressing the chicken Tva receptor but were 2-fold (E149K), 10-fold (Y142N), and 600-fold (Y142N/E149K) less efficient at infecting cells expressing the quail Tva receptor. These mutations identify key determinants of the interaction between the ALV(A) glycoproteins and the Tva receptor. We also conclude from these results that, at least for the wild-type and variant ALV(A)s tested, the receptor binding affinity was directly related to infection efficiency. (+info)
Role of calcium in protein folding and function of Tva, the receptor of subgroup A avian sarcoma and leukosis virus. (2/162)Tva is the cellular receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A). The viral receptor function of Tva is determined by a 40-residue cysteine-rich motif called the LDL-A module. In this study, we expressed and purified the wild-type (wt) Tva LDL-A module as well as several mutants and examined their in vitro folding properties. We found that, as for other LDL-A modules, correct folding and structure of the Tva LDL-A module is Ca2+ dependent. When calcium was present during in vitro protein folding, the wt module was eluted as a single peak by reverse-phase high-pressure liquid chromatography. Furthermore, two-dimensional nuclear magnetic resonance (NMR) spectroscopy gave well-dispersed spectra in the presence of calcium. In contrast, the same protein folded in vitro in the absence of calcium was eluted as multiple broad peaks and gave a poorly dispersed NMR spectrum in the presence of calcium. The calcium affinity (Kd) of the Tva LDL-A module, determined by isothermal titration calorimetry, is approximately 40 microM. Characterization of several Tva mutants provided further evidence that calcium is important in protein folding and function of Tva. Mutations of the Ca2+-binding residues (D46A and E47A) completely abrogated the Ca2+-binding ability of Tva, and the proteins were not correctly folded. Interestingly, mutations of two non-calcium-binding residues (W48A and L34A) also exerted adverse effect on Ca2+-dependent folding, albeit to a much less extent. Our results provide new insights regarding the structure and function of Tva in ASLV-A entry. (+info)
Isolation and characterization of nuclear RNA polymerase II from chicken myeloblastosis cells. (3/162)Nuclear RNA polymerases of chicken myeloblastosis cells were solubilized and fractionated by diethylaminoethyl-Sephades A25 column chromatography. Both alpha-amanitin-insenstitive (polymerase I) and- sensitive (polymerase II) species were isolated. Polymerase activity, contained two peaks of enzyme (IIa and IIb), which were further purified by glycerol gradient centrifugation. The partially purified enzymes were characterized by their requirement of four nucleoside triphosphates and metal ions and by their sensitivity to several inhibitors. The enzymes were compared with RNA polymearases derived from normal chickent bone marrow cells,and the total extractable myeloblastosis than in bone marrow cells. Polymearse II from both cell types was shown to be sensitive to cytosine arabinoside triphosphate inhibiton. (+info)
Avian erythroleukemia: a model for corepressor function in cancer. (4/162)Transcriptional regulation at the level of chromatin plays crucial roles during eukaryotic development and differentiation. A plethora of studies revealed that the acetylation status of histones is controlled by multi-protein complexes containing (de)acetylase activities. In the current model, histone deacetylases and acetyltransferases are recruited to chromatin by DNA-bound repressors and activators, respectively. Shifting the balance between deacetylation, i.e. repressive chromatin and acetylation, i.e. active chromatin can lead to aberrant gene transcription and cancer. In human acute promyelocytic leukemia (APL) and avian erythroleukemia (AEL), chromosomal translocations and/or mutations in nuclear hormone receptors, RARalpha [NR1B1] and TRalpha [NR1A1], yielded oncoproteins that deregulate transcription and alter chromatin structure. The oncogenic receptors are locked in their 'off' mode thereby constitutively repressing transcription of genes that are critical for differentiation of hematopoietic cells. AEL involves an oncogenic version of the chicken TRalpha, v-ErbA. Apart from repression by v-ErbA via recruitment of corepressor complexes, other repressors and corepressors appear to be involved in repression of v-ErbA target genes, such as carbonic anhydrase II (CAII). Reactivation of repressed genes in APL and AEL by chromatin modifying agents such as inhibitors of histone deacetylase or of methylation provides new therapeutic strategies in the treatment of acute myeloid leukemia. (+info)
Heterophil function and resistance to staphylococcal challenge in broiler chickens naturally infected with avian leukosis virus subgroup J. (5/162)Avian leukosis virus subgroup J has a high tropism for myeloid lineage cells and frequently induces neoplastic transformation of myelocytes. The impact of congenital avian leukosis virus subgroup J infection on the function of circulating heterophils and susceptibility to staphylococcal infection was investigated. Six-week-old broiler chickens negative for exogenous avian leukosis viruses or congenitally infected with avian leukosis virus subgroup J were inoculated intravenously with 10(6) colony-forming units of Staphylococcus aureus, and pre- and postinoculation heterophil function was assessed. All chickens developed a leukocytosis with heterophilia after inoculation, but total leukocyte and heterophil counts were significantly higher in leukosis-negative chickens than in virus-infected chickens. Tenosynovitis was more severe in leukosis-negative chickens, and 2/10 (20%) of the virus-infected chickens had no histologic evidence of tenosynovitis. Osteomyelitis in the tibiotarsus or tarsometatarsus developed in 5/10 (50%) of the chickens in each group. S. aureus was recovered from the hock joint of 6/10 (60%) of the chickens in each group. Heterophils from all chickens exhibited similar phagocytic ability pre- and postinoculation. Heterophils from virus-infected chickens exhibited less bactericidal ability preinoculation than did heterophils from leukosis-negative chickens. However, postinoculation bactericidal ability was similar in both groups. Avian leukosis virus subgroup J provirus was present in heterophils isolated from congenitally infected chickens. Heterophils isolated from broiler chickens congenitally infected with avian leukosis virus subgroup J exhibit no significant functional deficits, and infected and uninfected chickens exhibit similar susceptibility to staphylococcal infection. (+info)
Localization of avian leukosis virus subgroup J in naturally infected chickens by RNA in situ hybridization. (6/162)The novel subgroup J of avian leukosis virus (ALV-J) has emerged as a significant cause of myeloid neoplasia and weight suppression in broiler chickens. We investigated viral tropism using RNA in situ hybridization (ISH) in naturally infected chickens. Formalin-fixed tissues were collected from 12-day-old embryos (seven infected, two control) and from 0-week-old (four infected, one control), 3-week-old (five infected, one control), 6-week-old (five infected, one control), and 9-week-old (10 infected, two control) chickens naturally infected with ALV-J in ovo. A 636-base antisense riboprobe complementary to the 3' and 5' ends of the pol and env viral genes, respectively, was constructed. Strong positive staining was present in cardiac myocytes, Purkinje fibers, vascular and pulmonary smooth muscle, renal glomeruli, distal tubules, and pituitary glands. Light staining was present in gastrointestinal smooth muscle, thyroid and adrenal glands, and follicular medullae in the cloacal bursa. Staining was not present in any hematopoietic precursors. Tissues from newly hatched chicks exhibited the strongest and most consistent staining, whereas staining in embryos was minimal. RNA ISH confirmed the presence of ALV-J-specific nucleic acid within cytoplasmic inclusions in cardiac myocytes, Purkinje fibers, pituitary glands, and renal glomeruli. Viral tropism for cardiac myocytes and Purkinje fibers may relate pathogenetically to the cardiomyopathy and congestive heart failure described in index chicken flocks infected with ALV-J. Viral tropism for endocrine organs may relate pathogenetically to the weight suppression associated with infection. (+info)
Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis. (7/162)bic is a novel gene identified at a common retroviral integration site in avian leukosis virus-induced lymphomas and has been implicated as a collaborator with c-myc in B lymphomagenesis. It lacks an extensive open reading frame and is believed to function as an untranslated RNA (W. Tam, Gene 274:157-167, 2001; W. Tam, D. Ben-Yehuda, and W. S. Hayward, Mol. Cell. Biol. 17:1490-1502, 1997). The oncogenic potential of bic, particularly its ability to cooperate with c-myc in oncogenesis, was tested directly by expressing c-myc and bic, either singly or in pairwise combination, in cultured chicken embryo fibroblasts (CEFs) and in chickens using replication-competent retrovirus vectors. Coexpression of c-myc and bic in CEFs caused growth enhancement of cells. Most importantly, chick oncogenicity assays demonstrated that bic can cooperate with c-myc in lymphomagenesis and erythroleukemogenesis. The present study provides direct evidence for the involvement of untranslated RNAs in oncogenesis and provides further support for the role of noncoding RNAs as riboregulators. (+info)
Cardiomyopathy in broiler chickens congenitally infected with avian leukosis virus subgroup J. (8/162)Dilated cardiomyopathy and ascites in broiler chickens are frequently associated with rapid growth and pulmonary hypertension, but can be associated with some avian leukosis virus (ALV) infections. The novel subgroup J of ALV has a high cardiac tropism, but dilated cardiomyopathy has not been reported previously. We report a dilated cardiomyopathy incidence of 11.1% in broiler chickens congenitally infected with ALV subgroup J (ALV-J). Gross lesions included severe body weight suppression, cardiomegaly with biventricular dilation, right ventricular hypertrophy, visceral congestion, and ascites. Cardiac myocytes and Purkinje fibers contained 2- to 10-microm intracytoplasmic magenta inclusions that contained ALV-J-specific nucleic acid. Ultrastructurally, inclusions contained ribosomes and immature virions and were associated with myofibril disruption and disarray. Peracute centrilobular hepatic necrosis was present in most cases. ALV-J-associated cardiomyopathy may involve a direct viral effect on cardiac myocytes and Purkinje fibers. (+info)
Incidence of avian leukosis virus infection in broiler stocks...
Incidence of avian leukosis virus infection in broiler stocks and its effect on early growth.: Twenty-eight broiler breeder flocks were tested for avian leukosi
Rapid detection of the common avian leukosis virus subgroups by real-time loop-mediated isothermal amplification | Virology...
Subgroups A, B, E and J are the major subgroups of avian leukosis virus (ALV) infecting chickens. ALV infection has become endemic in China and has a significant negative effect on the poultry industry. Consequently, there is an urgent need for a specific, sensitive and rapid method for diagnosis and eradication of ALV. Therefore, we developed a simple and rapid real-time loop-mediated isothermal amplification (LAMP) reaction for the timely detection of the common ALV subgroups, whereby the amplification can be obtained in 35 min under isothermal conditions at 63 °C, ability to specific, sensitive and rapid detect all the common ALV subgroups. A set of four specific primers was designed to target the sequences of the pol gene of ALV, and the loop-mediated isothermal amplification (LAMP) assay were developed and compared with PCR and virus isolation methods. The results from specificity of the LAMP assay showed that only target ALVs DNA was amplified. The LAMP assay demonstrated a sensitivity of 20
Avian Leukosis, Lymphoid Leukosis, Leukosis/Sarkoma Group - El Sitio Avicola
Morbidity is low but mortality high. Mortality tends to be chronically higher than normal for a prolonged period. Egg production is somewhat reduced. There may be increased susceptibility to other infectious diseases due to damage to the immune system. Vertical transmission is most important by infection of the egg white in infected breeders (who are long-term carriers), lateral transmission is poor but infection may occur by the faecal-oral route, especially in young birds. In lymphoid leukosis the incubation period is about 4-6 months; it may be as short as 6 weeks for some of the other manifestations. The causative viruses are rapidly inactivated at ambient temperature and on exposure to most disinfectants ...
Quantitative Evaluation of DNA Methylation Patterns for ALVE and TVB Genes in a Neoplastic Disease Susceptible and Resistant...
Chicken endogenous viruses, ALVE (Avian Leukosis Virus subgroup E), are inherited as LTR (long terminal repeat) retrotransposons, which are negatively correlated with disease resistance, and any changes in DNA methylation may contribute to the susceptibility to neoplastic disease. The relationship between ALVE methylation status and neoplastic disease in the chicken is undefined. White Leghorn inbred lines 72 and 63 at the ADOL have been respectively selected for resistance and susceptibility to tumors that are induced by avian viruses. In this study, the DNA methylation patterns of 3∼6 CpG sites of four conserved regions in ALVE, including one unique region in ALVE1, the promoter region in the TVB (tumor virus receptor of ALV subgroup B, D and E) locus, were analyzed in the two lines using pyrosequencing methods in four tissues, i.e., liver, spleen, blood and hypothalamus. A significant CpG hypermethylation level was seen in line 72 in all four tissues, e.g., 91.86±1.63% for ALVE region2 in blood,
Orthodox life: E ELEMENTS IN OUR NUTRITION
It is important for us to know that the more chemical additives are contained in food, the less beneficial it is for our health. These chemical additives are used to add flavour, colour or aroma to the food and even a longer shelf life. The E code has been instituted by the European Union to indicate the presence of an approved particular chemical additive. Independent of whether the E trace elements are approved by the European Union, the more products we use that contain the E elements, the more we burden our health, especially if we consume them on a daily basis. The catalogue below is indicative and we hope that it will make us all more careful us consumers: we need to look very carefully at the ingredients of the products to be sure that they do not contain E elements ...
Lymphoid leukosis discovered in Legbar chicken - Texas A&M Veterinary Medical Diagnostic Laboratory
By Martin Ficken, DVM, PhD. Recently, one dead, female, Cream Legbar chicken was presented to the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) in Gonzales for necropsy. The bird had excellent feathering, was in good post-mortem condition, and weighed 1.06 kilograms.. Upon gross examination, mild breast muscle atrophy was present.The liver was enlarged approximately five times normal size and contained small white coalescing foci interpreted as neoplastic cells (Figure 1). The spleen was of normal size, but contained similar white foci.The kidney contained a nodular mass in the middle of the right renal chain that measured approximately 2 cm in diameter (Figure 2).The bursa contained a nodular mass that measured approximately 1 cm in diameter (Figure 3).The right lung was diffusely congested and edematous.All other systems contained no significant lesions.. Microscopic sections of liver were characterized by numerous coalescing foci of a uniform population of lymphoblasts that had ...
Leukosis mathematical model - Saint Petersburg State University
TY - JOUR. T1 - Leukosis mathematical model. AU - Kolpak, Eugeny Petrovich. AU - Abuzyarova, Raisa Tagirovna. AU - Kabrits, Sergey Alexandrovich. PY - 2018/1/1. Y1 - 2018/1/1. N2 - Aim and Scope: The present study is about developing the mathematical model of leukosis according to modern data on hematopoiesis among mammals. Materials and Methods: Three types of cells are considered in the model, one of which is represented by leukemic ones. The interaction of cells is considered as the competition for the functional space of dividing cells. For leukemia cells are the cells dividing at a higher speed as compared to all the others. Results and Discussion: The model of leukemic cells replacement with donor cells is considered as the introduction of more active cells than leukemic ones. The model is represented by the Cauchy problem for the system of ordinary differential equations. Conclusion: The violation of hematopoiesis functions is compared with a leading parameter change, which transfers the ...
Avian Leukosis - Everything2.com
Its another beautiful day on the Old McDonald|farm, and having fed and watered the horses, cows, sheep, and other assorted barnyard animals, you decide...
Group-specific-antigen dictionary definition | group-specific-antigen defined
group-specific-antigen definition: Noun (plural group specific antigens) 1. The genetic material that codes for the structural protein of a retrovirus...
28 | 日本U
Ꭺt the time of the MMA match, it is very important tһat you know everything about the activity. Make certain that you are educated on all the kinds of combating concerned in MMA. You ought to be aware tһat each fighter has its own specialty аnd adｖаntagе in the game while placing your bets. Think about examining the past fights to determine out which fighter won with what bеnefit. How it is carried out? Nicely, initial you will juѕt need to get all the info on all elements such as specific benefits, peгform ѕtyles ᧐r aⅼl theѕe elements that have offered an upper hand to the fighter throughout the match.. Beyond records, changes, and scratches, how can you choose the correct picks in horseraсing? Cеrtainlｙ not by choosing the horse because yߋu like his name-thatѕ never great, unless the horsеs title is Wingnut-for ѕоme rｅason we liкe that name!. The ⲟnline Dress up gameѕ haѕ stuffеd new craze in the younger girls and they all want to play them. They are ...
An immunochemotherapeutic system for the treatment of a transplanted m by J P. Glynn, B L. Halpern et al.
Glynn, J P.; Halpern, B L.; and Fefer, A, An immunochemotherapeutic system for the treatment of a transplanted moloney virus-induced lymphoma in mice. (1969). Subject Strain Bibliography 1969. 913 ...
Anti avian leukosis virus P27 protein monoclonal antibody / clone # 5E1-1F1 - Antibodymall
Avian sarcoma leukosis virus (ASLV) is an endogenous retrovirus that infects and can lead to cancer in chickens; experimentally it can infect other species of birds and mammals. ASLV replicates in chicken embryo fibroblasts, the cells that contribute to the formation of connective tissues. Lymphoid leukosis is the most common form of this disease and with typical presentation of gradual onset, persistent low mortality, and neoplasia of the bursa. Subgroups A, B, E and J are the major subgroups of avian leukosis virus (ALV) infecting chickens. ALV infection has become endemic in many countries and has a significant negative effect on the poultry industry.. ...
Antigenic variants of J subgroup avian leukosis virus: sequence analysis reveals multiple changes in the env gene. |...
HPRS-103, the prototype of avian leukosis virus (ALV) subgroup J, was isolated in 1989 from meat-type chickens from commercial flocks where it induces myelocytic myeloid leukosis (ML). The HPRS-103 env gene differs considerably from other ALV subgroups but shows high identity (75-97%) to env-like sequences of the different members of the EAV family of endogenous avian retroviruses. Recently, we have isolated several viruses related to HPRS-103 from cases of ML. Although these isolates showed properties of ALV subgroup J, the majority of them resisted neutralization by HPRS-103-specific serum, suggesting antigenic variation. The nucleotide sequence of the env gene of the variant viruses showed several substitutions resulting in amino acid changes especially clustered in the variable regions hr1, hr2 and vr3. Analysis of the data suggests that selection pressure, probably from the immune response, is driving the antigenic variation among the isolates. Phylogenetic analysis of the sequences showed the
Leukosis & BVD - Minnesota Dairy Herd Improvement Association
Bovine Leukosis is a disease caused by the Bovine Leukosis virus (BLV). This is a blood borne disease that dwells in the lymphocytes (white blood cells) in cattle. Only 5% of infected animals will exhibit the clinical symptoms of developing tumors in lymphatic tissue. The prevalence ofleukosis is wide spread. It is fairly common to find herds with a prevalence of 80-90%, however not very common to find herds that are completely free of leukosis. According to the NAHMS 96 study, 88.5% of dairy herds and 38.7% of beef herds are infected. Transmission occurs by the transfer of bodily fluids that contain infected white cells (blood, colostrum, milk). Anything from reusing without sanitizing contaminated needles, syringes, breeding sleeves, dehorners, or balling guns can transmit leukosis. Transmission can also occur through colostrum or to a fetus in utero. ...
Table - Lack of Evidence of Endogenous Avian Leukosis Virus and Endogenous Avian Retrovirus Transmission to Measles Mumps...
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Bursal Stem Cells as Targets for myc-Induced Preneoplastic Proliferation and Maturation Arrest | SpringerLink
Induction of lymphomas in the bursa of Fabricius of chickens by replication competent, non-transforming avian retroviruses (Avian Leukosis Virus, ALV) is both an economically significant, naturally...
Kaspersky Anti-Virus 2010 (1 User) - HardwareZone.com
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Reconstitution of retroviral fusion and uncoating in a cell- 2020
Edited by John M. Coffin, Tufts University School of Medicine, Boston, MA (received for review February 24, 2004) ArticleFigures SIInfo gt;5 kDa in size are required. Furthermore, later steps of avian sarcoma and leukosis virus reverse tran
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I was out at the Topeka Zoological Garden trying out a new combination: K 3 + Pentax 16 - 85 mm zoom + focal 2x mc converter. (I just bought the used
Virus-Host Interactions in the Development of Avian Leukosis Virus-Ind by Rosalinda Gram Foster
Avian leukosis virus (ALV)-induced osteopetrosis is a proliferative disorder of the bone affecting the growth and differentiation of osteoblasts. Osteopetrosis is a polyclonal disease in which cells of the bone contain, on average, multiple viral DNA copies. Osteopetrotic bone is also characterized by the accumulation of unintegrated viral DNA, suggesting an atypical life cycle of the virus in the infected osteoblasts. To better understand virus-host interactions in the induction of osteopetrosis by ALVs, infected chick osteoblast cultures and osteopetrotic bone were examined for aspects of the virus life cycle and effects of infection on osteoblast function. Levels of infection and virus expression were compared in cultured osteoblasts and osteopetrotic bone. Osteopetrotic bone contained higher levels of viral DNA and correspondingly higher levels of viral proteins than infected osteoblast cultures, suggesting a higher viral load in the diseased bone. A significant level of mature Gag protein was
Disease tropism of c-erbB: Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation<...
TY - JOUR. T1 - Disease tropism of c-erbB. T2 - Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation. AU - Pelley, R. J.. AU - Maihle, Nita Jane. AU - Boerkoel, C.. AU - Shu, H. K.. AU - Carter, T. H.. AU - Moscovici, C.. AU - Kung, H. J.. PY - 1989/1/1. Y1 - 1989/1/1. N2 - Avian leukosis virus induces erythroleukemia in chickens by proviral insertional mutation of the proto-oncogene c-erbB. The product of the insertionally activated c-erbB locus lacks the extracellular ligand-binding domain and is strictly leukemogenic. It has previously been demonstrated that the disease spectrum associated with aberrant c-erbB expression can be expanded by structural perturbation of the cytoplasmic domain of this protein. In this report, we use mutagenesis and retroviral vectors to identify specific mutations in the carboxyl-terminal domain of the insertionally activated c-erbB product that are sufficient to activate the sarcomagenic potential of this protein. ...
Identification of the Avian Myeloblastosis Virus Genome | Springer for Research & Development
In addition to neoplasias caused in chickens by helper viruses of the avian myeloblastosis virus (AMV) complex, acute myeloblastic leukemia is induced by a defective leukemogenic component. To...
On the Nomenclature of Viruses Associated with AIDS 
Traditionally, virus isolates have been named most commonly for the disease from which they were isolated - e.g. influenza, poliomyelitis, visna, foot-and-mouth disease, and the like. A smaller number are named for the place of isolation - Coxsackie, Sindbis, and Sendai viruses are a few examples, and a mercifully small number are named for their discoverers - alone or in combination with other features - such as Epstein-Barr virus, Rous sarcoma virus, etc. With retroviruses, it is also usual to append the species of origin to the name - avian leukosis virus, human T-cell lymphoma virus, baboon endogenous virus, etc. Unlike most other organisms, the naming of new virus isolates has usually been a trivial prerogative of the isolator, and not subject to review by other workers in the field . This has, in general, caused little difficulty so long as the names chosen were novel and did not presuppose unproven relationships. Significant confusion has been created in the past, however, by injudicious ...
[email protected] Blog - University of Rochester Medical Center
A team led by Xin Li, Ph.D., assistant professor in the departments of Biochemistry and Biophysics and Urology at the University of Rochester School of Medicine and Dentistry, analyzed rooster testes to find out.. Chickens acquire and harbor a wide variety of viruses. When a virus infects a host, like a chicken, it does everything it can to survive. One method of survival is inserting its genetic material into the chickens genome. Over generations, the inserted virus accumulates mutations and eventually becomes harmless to the animal, but its still a part of the chickens genetic material.. Lis team focused on avian leukosis virus, which commonly infects and can lead to cancer in domestic chickens. Through molecular and genetic analysis, they discovered that chickens turn these old, existing viruses into piRNA-producing machines. When faced with a new avian leucosis virus (there are many different viruses in the family), the old viruses pump out piRNAs that defend the germ cells, ensuring the ...
Erythroblastosis faetalis | Article about Erythroblastosis faetalis by The Free Dictionary
Looking for Erythroblastosis faetalis? Find out information about Erythroblastosis faetalis. a disease manifested at birth or shortly thereafter and generally caused by incompatibility of the mothers blood with that of the fetus with respect to the... Explanation of Erythroblastosis faetalis
Avian myeloblastosis ATCC ® VR-1542AS-Gt™
Avian myeloblastosis ATCC ® VR-1542AS-Gt™ Designation: antiserum against AMV RT [NCI HE 599] Application: goat antiserum against the Avian Myeloblastosis Virus (AMV) Reverse Transcriptase (RT)
Successful heterotransplantation of l1210 mouse leukosis into un- trea by C A. Apffel and J H. Peters
Apffel, C A. and Peters, J H., Successful heterotransplantation of l1210 mouse leukosis into un- treated adult hamsters. Abstr. (1968). Subject Strain Bibliography 1968. 45 ...
BOVINE LEUKOSIS VIRUS PATHOGENESIS - UC Davis
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Erythroblastoses | Article about erythroblastoses by The Free Dictionary
Looking for erythroblastoses? Find out information about erythroblastoses. The abnormal presence of erythroblasts in the blood. A virus disease of birds; considered to be part of the avian leukosis complex in which there is an... Explanation of erythroblastoses
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used to derive intake values did not include consideration for other applications. However, with the increasing globalization of information and the identification of a variety of factors specific to different population subgroups (e.g ...
This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission. ...
Detection of reticuloendotheliosis virus by immunohistochemistry and in situ hybridization in experimentally infected Japanese...
TY - JOUR. T1 - Detection of reticuloendotheliosis virus by immunohistochemistry and in situ hybridization in experimentally infected Japanese quail embryos and archived formalin-fixed and paraffin-embedded tumours. AU - Santos, Vitor L S L. AU - Williams, Susan M.. AU - Zavala, Guillermo. AU - Barbosa, Taylor. AU - Zhang, Jian. AU - Cheng, Sunny. AU - Shivaprasad, H L. AU - Hafner, Scott. AU - Fadly, Aly. AU - Santos, Renato L.. AU - Brown, Corrie C.. PY - 2008/8. Y1 - 2008/8. N2 - Reticuloendotheliosis virus (REV) infection can result in immunosuppression, a runting syndrome, high mortality, acute reticulum cell neoplasia, or T-cell and/or B-cell lymphomas, in a variety of domestic and wild birds. Histopathological changes in REV infection are not sufficient to differentiate it from avian lymphoid leukosis and Mareks disease, and currently there are no available in situ diagnostic methods for detection of active REV presence in pathologic specimens. To develop immunohistochemistry and in situ ...
Occupational exposure to poultry and prevalence of antibodies against Mareks disease virus and avian leukosis retroviruses. |...
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Erythroblastosis fetalis. Causes, symptoms, treatment Erythroblastosis fetalis
Description of disease Erythroblastosis fetalis. Treatment Erythroblastosis fetalis. Symptoms and causes Erythroblastosis fetalis Prophylaxis Erythroblastosis fetalis
Penggunaan teknik reaksi rantai polimerase (PCR) DNA proviral dari virus enzootic bovine leukosis | Hemera Zoa
A polymerase chain reaction was developed to detect the proviral DNA of bovine leukimia virus in bovine lymphocytes. Milk and blood samples from infected and uninfected cows were tested. None of the bovine leukosis free animals gave a positive response and 58% of the infected cows showed positive signals. When the DNAs 25ul of blood. 25.000 lymphocytes or 1.000 lymphocytes were amplified. positive results were recorded more frequently in cows with persistent lymphocytes than in cows with normal lymphocyte counts ...
Search Results | Journal of Experimental Medicine | Rockefeller University Press
Previous reports have shown that spleen cells from nonimmune adult mice of certain strains do regularly kill Moloney leukemia virus-induced lymphomas in short-term 51Cr release assays. This naturally occuring killer (NK) cell had low adherent properties and had the morphological appearance of a lymphocyte. Still it lacked surface characteristics of mature T or B lymphocytes. In the present report a functional study was carried out, comparing in parallel the NK system, the T-cell killing across an H-2 barrier (anti-P815), and the antibody-dependent cell-mediated chicken red blood cell (CRBC) system. In contrast to the effector cells in the CRBC system, the NK cells were insensitive to erythrocyte antibody complement (EAC) rosette depletion and would pass through nylon wool columns. NK activity was not inhibited by the presence of heat-aggregated human or mouse gamma globulin, in contrast to the strong inhibition noted in the CRBC system. Sensitivity to trypsin pretreatment was noted in the NK ...
erythroblastosis fetalis - Page 2 - Biology-Online
At the first baby, there are no antibodies against Rh+, while birth, blood of the baby and the mother mixes and there are some antibodies produced, And those antibodies make the second baby die or born with some abnormalities. IgG can pass through placenta. Actually erythroblastosis fetalis can also be defined as the lysis of fetal RBCs by maternal IgGs ...
Erythroblastosis Fetalis - Causes, Symptoms, Diagnosis, Treatment & Prevention
Erythroblastosis fetalis occurs due to Rh incompatibility between the mother and the fetus, resulting in severe anemia and sometimes death of the fetus.
Živa - Sociální chování a komunikace nosorožců tuponosých a nosorožců Cottonových (Ivana Cinková)
The Northern and Southern White Rhinos (Ceratotherium cottoni and C. simum) have the most developed social system among all the rhinoceros species. Until recently, little has been known about their communication and social behaviour. This paper presents the results of four recent studies involving research into the social behaviour and vocal and olfactory communication of these species both in the wildlife reserves in South Africa and in zoological gardens. ...
Subject: Caracal caracal / Publication Year: 2012 / Subject: 4 selected - PubAg Search Results
In July 2009, a 14-yr-old male caracal (Caracal caracal) at the National Zoological Gardens of South Africa was found, on abdominal ultrasound, to have a single large cystolith. The cystolith was removed, and the composition was determined to be 100% cystine. Blood and urine samples were also collected from three other apparently healthy caracals at the zoo and were submitted, together with the sa ...
BMS treats pupils to the zoo | News24
A TOTAL of 64 pupils and four teachers from Khwezi Primary in Sobantu were treated to an outing to the Natal Zoological Gardens last week, courtesy of Bluff Meat Supply.
Evaluation of genetic variation within and between different chicken lines by DNA fingerprinting. Genetic similarity using DNA...
Evaluation of genetic variation within and between different chicken lines by DNA fingerprinting. Genetic similarity using DNA fingerprinting in cattle to determine relationship coefficient
02 Февраля 2014 - AMV by Uchiha-style
Здравсвуйте пользователи форума amv.at.ua, вчера пользователь под ником Olechkalype просила меня выложить супермодные новинки Компьютерные аксессуары/Графические планшеты в 2014, а так же сотовые бренда Intuos Pro Special Ed., так вот наконецто нашла время для этого, админы прошу не удалять, а перенести в соответствующий раздел, если я ошиблась например Компьютерные аксессуары/Графические планшеты ))) всех обнимаю ...
08 Февраля 2014 - AMV by Uchiha-style
Пожалуй, самым разочаровывающим итогом 2013 года стало сползание в экономический застой. На протяжении года снижались как темпы роста промышленности, так и ВВП. Если в начале года еще казалось, что экономика вот-вот разгонится и из состояния «технической рецессии» войдет в фазу роста, то уже весной тональность заявлений финансовых властей смен ...
Proper processing of avian sarcoma/leukosis virus capsid proteins is required for infectivity<...
TY - JOUR. T1 - Proper processing of avian sarcoma/leukosis virus capsid proteins is required for infectivity. AU - Xiang, Y.. AU - Thorick, R.. AU - Vana, M. L.. AU - Craven, R.. AU - Leis, J.. N1 - Copyright: Copyright 2007 Elsevier B.V., All rights reserved.. PY - 2001. Y1 - 2001. N2 - The formation of the mature carboxyl terminus of CA in avian sarcoma/leukemia virus is the result of a sequence of cleavage events at three PR sites that lie between CA and NC in the Gag polyprotein. The initial cleavage forms the amino terminus of the NC protein and releases an immature CA, named CA1, with a spacer peptide at its carboxyl terminus. Cleavage of either 9 or 12 amino acids from the carboxyl terminus creates two mature CA species, named CA2 and CA3, that can be detected in avian sarcoma/leukemia virus (R. B. Pepinsky, I. A. Papayannopoulos, E. P. Chow, N. K. Krishna, R. C. Craven, and V. M. Vogt, J. Virol. 69:6430-6438, 1995). To study the importance of each of the three CA proteins, we introduced ...
Host range of Rous sarcoma virus pseudotype RSV(HPRS-103) in 12 avian species: support for a new avian retrovirus envelope...
The host ranges of the Rous sarcoma virus (RSV) pseudotype RSV(HPRS-103) of a novel avian leukosis virus (ALV), strain HPRS-103, and representative RSV pseudotypes of subgroups A to F, have been determined in embryo fibroblasts from 12 avian species. Domestic fowl, red jungle fowl, Sonnerat's jungle fowl and turkey were susceptible to infection by RSV(HPRS-103); ring-necked pheasant, Japanese green pheasant, golden pheasant, Japanese quail, guinea-fowl, Peking duck, Muscovy duck and goose were resistant. The host range pattern of RSV(HPRS-103) differs from those of viruses of subgroups A to G and I, and provides support for placing the HPRS-103 strain of ALV in a new envelope subgroup, designated J.
14th International Mouse Genome Conference (2000)
2Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4472 USA. Wnt1 signaling has been implicated as one factor involved in neural crest-derived melanocyte (NC-M) development. Mice deficient for both Wnt1 and Wnt3a have a marked deficiency in trunk neural crest derivatives including NC-Ms (1). We have used cell lineage-directed gene targeting of Wnt signaling genes to examine the effects of Wnt signaling in mouse neural crest development. Gene expression was directed to cell-lineages by infection with subgroup A avian leukosis virus vectors (RCAS) (2) in lines of transgenic mice that express the retrovirus receptor tv-a (2). Transgenic mice with tva in either nestin expressing neural precuror cells (line Ntva) or dopachrome tautomerase (DCT) expressing melanoblasts (line DCTtva) were analyzed. We over-stimulated Wnt signaling in two ways: directed gene transfer of Wnt1 to Ntva+ cells and transfer of b-catenin to DCTtva+ NC-M precursor ...
Content of squalene and sterols in tissues of the hemopoietic system in normal rats and in experimental leukemia
Abstract: Contents of scvalene, sterols and their derivatives were studied in lymphoid tissues as well as in liver and kidney tissues of normal rats and the animals with Shvetz experimental leukosis. Amount of cholesterol and of its precursor scvalene was distinctly decreased simultaneously with an increase in total content of nonsaponified substances in thymus, spleen, bone marrow and liver tissue of rats with experimental leukosis. Scvalene was increased in kidney tissue. Simultaneous accumulation of hydroxycholesterol derivatives, among which 7-beta-hydroxycholesterol was identified, was observed in these tissues under conditions of leukosis. Role of cholesterol hydroxyderivatives in biosynthesis of sterols is discussed ...
Veterinary Tests | RINGBIO
All products about animal diseas diagnosis and animal research use. From African swine fever, PRRSV, PCV to swine pregnancy, from avian influenza to avian leukosis, from foot-and-mouth disease to brucella testing. What you need is our direction of development and research.
Dissociation and isolation of the subunits of avian myeloblastosis vir by Mae Joanne Rosok
Rosok, Mae Joanne, Dissociation and isolation of the subunits of avian myeloblastosis virus RNA-directed DNA polymerase (1977). Graduate Student Theses, Dissertations, & Professional Papers. 6828 ...
Kolkata Zoo, Zoological Garden Alipure, Kolkata
BEHAVIOUR AND FOOD HABIT : Eastern grey kangaroos are gregarious and form open-membership groups. The groups are made up of 2-3 females and their offspring with the same number of males of which one is dominant. They exist in a dominance hierarchy and the dominant individuals gain access to better sources of food and areas of shade. However, kangaroos are not territorial and usually fight only when females are in estrous. Females may form strong kinship bonds with their female relatives. Females with living female relatives have a greater chance of reproducing. They are predominantly grazing animal. They are herbivores, but will eat a range of plants including fungi in some cases. With the grasses they prefer to eat young green shoots. ...
Download Agents Transmissible from Simians to Man by Manfred Brack PDF - Vlog E-books
By Manfred Brack. The contacts among guy and nonhuman primates permit the transmission of mic- roorganisms from one species to the opposite. Such touch may perhaps take place at particularly range- ent degrees: guy and nonhuman primates may possibly percentage an identical surroundings together with the presence of vectors within the international locations of origins of monkeys and apes; the animals are captured to be bought or used for nutrients; box researchers need to remain close to the ani- mals within the wild; an out of control human inhabitants will get shut adequate to nearly contact the animals in zoological gardens world wide; puppy proprietors identify physically touch and eventually researchers doing surgical procedure or necropsies are uncovered to an elevated variety of pathogens liberated from the organs and physique fluids. frequently monkeys and apes are extra threatened with catching the microorgan- isms indigenous to guy than vice versa, yet however outbreaks of precise ...
Zoo News Digest: October 2015
Obesity has been identified as a life-threatening condition among human beings. But as officials in the Delhi zoo have realised over the last year, it can stall life in the animal kingdom too. Thats why they are returning Salman, a 12-year-old jaguar, to Kerala with this stinging verdict: hes too fat to breed. Salman was borrowed on a breeding loan from the Thiruvananthapuram Zoological Garden last October, but has since shown complete disinterest in pairing up with the lone female jaguar in the National Zoological Park here, say Delhi zoo officials. They say Salman has reached out for its meals more keenly than for Kalpana, the female jaguar. He was brought on a breeding loan but it has been over a year and Salman has shown no interest in mating. In fact, the female is seen trying to entice him but he lies in a corner and refuses to respond. He is too fat to breed, Delhi zoo curator Riaz Khan told The Indian Express. Now we know for sure nothing is going to happen. So it is best ...
Subject: Caracal caracal / Subject: South Africa / Text Availability: Citation in PubAg - PubAg Search Results
In July 2009, a 14-yr-old male caracal (Caracal caracal) at the National Zoological Gardens of South Africa was found, on abdominal ultrasound, to have a single large cystolith. The cystolith was removed, and the composition was determined to be 100% cystine. Blood and urine samples were also collected from three other apparently healthy caracals at the zoo and were submitted, together with the sa ...
Zoologischer Garten in Krefeld, Niederrhein, Nordrhein-Westfalen
D-Krefeld, Rhein, Niederrhein, Rheinland, Nordrhein-Westfalen, NRW, D-Krefeld-Bockum, Krefelder Zoo, Spitzmaulnashorn, Schwarzes Nashorn, Diceros bicornis, D-Krefeld, Rhine, Lower Rhine, Rhineland, North Rhine-Westphalia, NRW, D-Krefeld-Bockum, zoological garden Krefeld, black rhinoceros, hook-lipped rhinoceros, Diceros bicornis *** Local Caption *** D-Krefeld, Rhine, Lower...
This family now includes the following genera: Subfamily Orthoretrovirinae: Genus Alpharetrovirus; type species: Avian leukosis ...
"The Poultry Guide - Avian Lymphoid Leukosis". Archived from the original on 2017-12-11. Retrieved 2007-12-12. v t e. ... Lymphoid leucosis is a disease that affects chickens, caused by the retrovirus Avian leukosis virus. It is a neoplastic disease ...
Lymphoid Leukosis A, B; Avian Lymphoid Leukosis Virus; Lymphoid Leukosis Viruses A,B,C,D,E,J; Marek's Disease (Serotypes 1,2, 3 ... Avian Nephritis Virus, Avian Paramyxovirus Type 2, Avian Reovirus S 1133, Avian Rhinotracheitis Virus; Avian Rotavirus; Avian ... Avian Adenovirus Group II (HEV), Avian Adenovirus Group III (EDS), Avian Encephalomyelitis, Avian Influenza (Type A), ... For SPF eggs the specific pathogens are: Avian Adenovirus Group I, ...
Peter K. Vogt
Rubin, H; Vogt PK (1962). "An avian leukosis virus associated with stocks of Rous sarcoma virus". Virology. 17: 184-94. doi: ... Cite journal requires ,journal= (help) Vogt, PK; Ishizaki R (1966). "Patterns of viral interference in the avian leukosis and ... Maki, Y; Bos TJ; Davis C; Starbuck M; Vogt PK (1987). "Avian sarcoma virus 17 carries the jun oncogene". Proc Natl Acad Sci U S ... "Nobel Prize 1989". Duesberg, PH; Bister K; Vogt PK (1977). "The RNA of avian acute leukemia virus MC29". Proc Natl Acad Sci U S ...
Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ...
Species include the Rous sarcoma virus, avian leukosis virus, and avian myeloblastosis virus. Not all animals that can infect ...
Curristin SM, Bird KJ, Tubbs RJ, Ruddell A (1997). "VBP and RelA regulate avian leukosis virus long terminal repeat-enhanced ...
Avian Sarcoma and Leukosis Viruses (ASLV) have ten subgroups (A through J). The envelope glycoprotein of subgroup A is called ... The Env proteins of the Avian Sarcoma and Leukosis virus (ASLV) and the Murine Leukemia Virus (MLV) are both trimers of SU-TM ... Barnard RJ, Narayan S, Dornadula G, Miller MD, Young JA (October 2004). "Low pH is required for avian sarcoma and leukosis ... Balliet JW, Gendron K, Bates P (April 2000). "Mutational analysis of the subgroup A avian sarcoma and leukosis virus putative ...
Retrovirus direct repeat 1 (dr1)
Rous sarcoma and Avian leukosis viruses (Alpharetroviruses and Avian type C retroviruses). dr1 is required for efficient viral ... Aschoff JM, Foster D, Coffin JM (September 1999). "Point mutations in the avian sarcoma/leukosis virus 3' untranslated region ... The direct repeat 1 (dr1) element is an RNA element commonly found in the 3' UTR of Avian sarcoma, ...
Anna Marie Skalka
Her initial focus used the avian sarcoma leukosis viruses (ASV) of chickens as a model system. With Bill McClements and others ... the laboratory cloned part of the avian endogenous provirus ev-1 as well as its integration site; the results suggested ...
Newly hatched chicks infected with Avian leukosis virus will begin to form tumours that will begin to appear in their bursa of ... These tumours are normally derived from one mutated/transformed cell (clonal in origin). Avian leukosis virus is an example of ...
Olive Griffith Stull
She was later employed as an agent of the USDA to investigate the diseases of poultry and avian leukosis. The abbreviation ...
... after Marek's disease and avian leukosis virus. The various syndromes caused by REV resemble both Marek's and avian leukosis. ... The Avian Diagnostic and Oncology Laboratory, in East Lansing, MI is the primary laboratory for research in REV and other tumor ... The American Association of Avian Pathologists maintains a fact sheet on viral tumor diseases. Swayne, David E.; Glisson, John ... Reticuloendotheliosis virus represents a third distinct etiological group of avian viral neoplasms, ...
KOREC, E., & HLOŽÁNEK, I. Detection of avian leukosis virus group-specific antigens in feather pulp of chickens by Elisa. Folia ... KOREC, E., HLOŽÁNEK, I., & BENDA, V. A rapid detection of avian oncovirus group-specific antigens in feather pulp by the enzyme ...
Bang and Ellerman demonstrated that avian sarcoma leukosis virus could be transmitted between chickens after cell-free ... Rous, Peyton (1910). "A Transmissible Avian Neoplasm (Sarcoma of the Common Fowl)". Journal of Experimental Medicine. 12 (5): ...
In coinfected cells, the retroviral DNA of the avian leukosis virus can integrate into the MDV genome, producing altered ... for instance between Avian sarcoma leukosis virus and Marek's disease virus (MDV) in domestic fowl. Both ...
... in horses Leucosis in sheep Feline leucosis Feline leukemia virus Avian leucosis and related diseases Avian sarcoma leukosis ... ISBN 0-7020-0718-8. H. Graham Purchase and L.N. Payne, Leukosis/sarcoma Group, in Diseases of poultry, ed. by M.S. Hofstad, ...
American Literary Version Avian leukosis virus Autoliv (ticker symbol) This disambiguation page lists articles associated with ...
List of MeSH codes (C04)
... avian MeSH C04.619.857.822 - sarcoma, yoshida MeSH C04.619.935.120 - avian leukosis MeSH C04.619.935.313 - epstein-barr virus ... enzootic bovine leukosis MeSH C04.557.337.372 - leukemia, experimental MeSH C04.557.337.372.216 - avian leukosis MeSH C04.557. ... avian leukosis MeSH C04.619.531.594 - leukemia L1210 MeSH C04.619.531.602 - leukemia L5178 MeSH C04.619.531.782 - leukemia p388 ... avian MeSH C04.651.600.500 - multiple endocrine neoplasia type 1 MeSH C04.651.600.505 - multiple endocrine neoplasia type 2a ...
Transporter Classification Database
Family 1.G.12 The Avian Leukosis Virus gp95 Fusion Protein (ALV-gp95) Family 1.G.13 The Orthoreovirus Fusion-associated Small ... 1.A.39 Type C influenza virus CM2 channel family 1.A.40 Human immunodeficiency virus type I Vpu channel family 1.A.41 Avian ...
List of MeSH codes (C22)
... avian leukosis MeSH C22.131.321 - fowlpox MeSH C22.131.450 - influenza in birds MeSH C22.131.498 - malaria, avian MeSH C22.131. ... avian MeSH C22.131.921 - tuberculosis, avian MeSH C22.180.350 - feline acquired immunodeficiency syndrome MeSH C22.180.440 - ... enzootic bovine leukosis MeSH C22.196.274 - ephemeral fever MeSH C22.196.339 - freemartinism MeSH C22.196.400 - hemorrhagic ...
Viruses portal Avian sarcoma leukosis virus (ASLV) Endogenous viral element ERV3 HERV-FRD Horizontal gene transfer Jaagsiekte ...
List of MeSH codes (C02)
... avian leukosis MeSH C02.782.815.200 - deltaretrovirus infections MeSH C02.782.815.200.260 - enzootic bovine leukosis MeSH ... avian MeSH C02.782.930.100 - alphavirus infections MeSH C02.782.930.100.370 - encephalomyelitis, equine MeSH C02.782.930.100. ...
... avian sarcoma leukosis virus Marek's disease Newcastle disease Viral arthritis Avian influenza Fowl pox Epidemic tremor Avian ... caused by Histomonas meleagridis Coccidiosis Ergotism Aspergillosis Sour crop Ringworm Avian Influenza Fowl Pox Gallid or Avian ... Chicken anaemia virus Infectious bursal disease also known as IBD or Gumboro disease Lymphoid leukosis caused by ... Gumboro Lymphoid Leukosis Marek's Disease Newcastle Disease Poultry. ...
List of MeSH codes (B04)
... avian MeSH B04.820.650.070.500 - leukosis virus, avian MeSH B04.820.650.070.550 - myeloblastosis virus, avian MeSH B04.820. ... avian MeSH B04.909.574.807.070.500 - leukosis virus, avian MeSH B04.909.574.807.070.550 - myeloblastosis virus, avian MeSH ... avian MeSH B04.909.777.731.070.500 - leukosis virus, avian MeSH B04.909.777.731.070.550 - myeloblastosis virus, avian MeSH ... avian MeSH B04.820.565.400.410 - hepatitis a virus MeSH B04.820.565.400.410.500 - hepatitis a virus, human MeSH B04.820.565.700 ...
Avian immune system
The most common immunosuppressive viruses are Infectious Bursal Disease Virus (IBDV), Avian Leukosis, Marek's Disease (MD) and ... "Development of the Avian Immune System." Avian Immunology. 4:51-66. Masteller EL, Pharr GT, Funk PE, Thompson CB (1997). "Avian ... Viertlboeck B, Göbel TWF (2008). "Avian T cells: antigen recognition and lineages." Avian Immunol. 6:91-105. Kaiser P, Rothwell ... avian influenza, giardiasis and cryptosporidiosis. These zoonotic diseases can be transmitted to humans. In the case of avian ...
1908: Vilhelm Ellerman and Olaf Bang, University of Copenhagen, first demonstrated that avian sarcoma leukosis virus could be ... "A Transmissible Avian Neoplasm (Sarcoma of the Common Fowl)". Journal of Experimental Medicine. 12 (5): 696-705. doi:10.1084/ ... could be caused by a virus began with the experiments of Oluf Bang and Vilhelm Ellerman in 1908 who first show that avian ...
Avian sarcoma leukosis virus
... is characterized by a wide range of tumors, the most common of which are lymphomas. Lymphoid ... Avian sarcoma leukosis virus (ASLV) is an endogenous retrovirus that infects and can lead to cancer in chickens; experimentally ... The American Association of Avian Pathologists maintains a fact sheet on viral tumor diseases. "Leukosis/Sarcoma Group". The ... ISBN 978-1-118-71973-2. Riddell, C. (May-June 1999). "The current problem with Avian Leukosis J Virus". California Poultry ...
List of virus species
Avian carcinoma Mill Hill virus 2 Avian coronavirus Avian coronavirus 9203 Avian dependoparvovirus 1 Avian leukosis virus Avian ... 11 Avian metaavulavirus 14 Avian metaavulavirus 15 Avian metaavulavirus 2 Avian metaavulavirus 20 Avian metaavulavirus 5 Avian ... 18 Avian orthoavulavirus 19 Avian orthoavulavirus 21 Avian orthoavulavirus 9 Avian orthoreovirus Avian paraavulavirus 3 Avian ... metaavulavirus 6 Avian metaavulavirus 7 Avian metaavulavirus 8 Avian metapneumovirus Avian myeloblastosis virus Avian ...
Endogenous viral element
Ancient DNA Avian sarcoma leukosis virus (ASLV) Endogenous retrovirus ERV3 HERV-FRD Jaagsiekte sheep retrovirus (JSRV) Koala ...
Avian sarcoma leukosis virus - Wikipedia
Avian sarcoma leukosis virus is characterized by a wide range of tumors, the most common of which are lymphomas. Lymphoid ... Avian sarcoma leukosis virus (ASLV) is an endogenous retrovirus that infects and can lead to cancer in chickens; experimentally ... The American Association of Avian Pathologists maintains a fact sheet on viral tumor diseases. "Leukosis/Sarcoma Group". The ... ISBN 978-1-118-71973-2. Riddell, C. (May-June 1999). "The current problem with Avian Leukosis J Virus". California Poultry ...
Retrovirus - Wikipedia
Backyard Poultry Forum • View topic - A blood test for Avian Leukosis ? Vet question
Eradication of avian leukosis virus from primary breeding stocks is the most effective means to control avian leukosis virus ... subgroup E avian leukosis virus have also been used. PCR has been used to detect and characterize avian leukosis virus strains ... subgroup E avian leukosis virus have also been used. PCR has been used to detect and characterize avian leukosis virus strains ... Ive been searching online for information about Avian Leukosis and what to do if your bird might have it. So far it seems only ...
A genetically engineered commercial chicken line is resistant to highly pathogenic avian leukosis virus subgroup J | The...
In chickens, avian leukosis virus subgroup J (ALV-J) represents an important pathogen that causes severe economic loss. Until ... In chickens, avian leukosis virus subgroup J (ALV-J) represents an important pathogen that causes severe economic loss. Until ... Home » Publications » A genetically engineered commercial chicken line is resistant to highly pathogenic avian leukosis virus ... A genetically engineered commercial chicken line is resistant to highly pathogenic avian leukosis virus subgroup J. ...
Table - Lack of Evidence of Endogenous Avian Leukosis Virus and Endogenous Avian Retrovirus Transmission to Measles Mumps...
Lack of Evidence of Endogenous Avian Leukosis Virus and Endogenous Avian Retrovirus Transmission to Measles Mumps Rubella ... Lack of Evidence of Endogenous Avian Leukosis Virus and Endogenous Avian Retrovirus Transmission to Measles Mumps Rubella ... Western blot antibody reactivity to the p27 gag protein of the endogenous avian leukosis virus (ALV) in vaccine recipients and ... Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Avian Disease and Oncology Laboratory ...
Regulatory Archives - Washington Report
Viral Oncogenesis | Page 4 | The Pirbright Institute
A major challenge for this comes from a plethora of diseases, particularly those caused by a number of major avian viral ... Among the avian diseases, neoplastic diseases (cancers) induced by pathogens such as ... Avian oncogenic viruses such as avian leukosis and Mareks disease viruses are major causes of cancer in chickens worldwide. ... Among the avian diseases, neoplastic diseases (cancers) induced by pathogens such as Mareks disease, avian leukosis and ...
Search Results - ScienceBase - ScienceBase-Catalog
Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly ... avian leukosis virus, endogenous, All tags... enhancers, hybrids, long terminal repeat, upstream enhancer sequences, virus, ... avian leukosis virus, c-myc gene, chickens, All tags... genes, integration, lymphoma, orientation, relationship, restriction ... avian leukosis virus, deletion mutant, genes, All tags... nucleotide sequence, oncogenes, restriction endonuclease mapping, v- ...
B-lymphoma induction by reticuloendotheliosis virus: Characterization of a mutated chicken syncytial virus provirus involved in...
Nondefective reticuloendotheliosis virus induces chicken bursal lymphoma in a manner similar to that of avian leukosis virus. ... N2 - Nondefective reticuloendotheliosis virus induces chicken bursal lymphoma in a manner similar to that of avian leukosis ... AB - Nondefective reticuloendotheliosis virus induces chicken bursal lymphoma in a manner similar to that of avian leukosis ... "Nondefective reticuloendotheliosis virus induces chicken bursal lymphoma in a manner similar to that of avian leukosis virus. ...
Results On Cells - Blog
Part 4 - Critical thinking and future food
Iranian Journal of Veterinary Research - Articles List
Food Safety Modernization Act
Tests? | IMMABLOG
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Search Results - ScienceBase - ScienceBase-Catalog
... avian leukosis virus, deletion mutant, genes, All tags... nucleotide sequence, oncogenes, restriction endonuclease mapping, v- ... avian myelocytomatosis virus MC29, genes, genomes, All tags... man, nucleotide sequence, onc gene, relationship, Fewer tags ... Nucleotide sequence of the full-length DNA copy of the avian influenza A virus neuraminidase gene belonging to N7 antigenic ... On the relationship between the transforming onc genes of avian Rous sarcoma and MC29 viruses and homologous loci of the ...
Agriculture, Dairy & Animal Science
genome | The Inquisitive Biologist
State of Oregon: Animal Health Lab - Laboratory Information
Ask the Expert June/July 2020 - Backyard Poultry
Some may be caused by a virus such as leukosis, or it may be more of a spontaneous cancer. I suppose she could have some other ... As always, taking a chicken or two to a veterinary diagnostic lab, or an avian veterinarian would be best, to get a firm ... It might be good to contact an avian veterinarian, or your state veterinary diagnostic lab, to try to get a firm diagnosis with ...
Common Cow Diseases to Watch Out For
Enzootic Bovine Leukosis This disease, commonly referred to as EBL since its quite a mouthful, usually occurs in adult cattle ... Australia has been free of some of the worlds most serious animal diseases like foot-and-mouth disease and avian influenza. ... who are infected with the bovine leukosis virus. Cattle over three years of age usually develop persistent lymphocytosis and ...
Animal health | Sub-topic | GOV.WALES
Avian influenza (bird flu): advice for pet owners. How to prevent pet birds, cats and other animals catching avian influenza ( ... Enzootic bovine leukosis. Clinical signs and what to do if you suspect infection ... Revocation of the Avian Influenza Prevention Zone. The Avian Influenza Prevention Zone (AIPZ), which has been in place since 11 ... Avian influenza (bird flu). Avian influenza is a highly contagious viral disease. It affects the respiratory, digestive or ...
Egg drop syndrome (or EDS)
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ChickensVirusesMyeloidRetrovirusesTumorsLymphoidSubgroup B avian leukoFlocksReceptorRecombinantEndogenous avian leukoResistance to avian leukoViralQuailNeoplastic diseasePoultrySubgroupsSpeciesRetrovirus that can induceExogenousReticuloendotheliosis virusDiseasesGeneSarcoma virusAntigenBirdsGenomeLymphomasStrainsDiseaseLeucosis virusDetectionSequenceELISA
- In recent years, cases of avian leukosis virus subgroup J (ALV-J) infection and tumors in commercial layer chickens and breeders of egg-type chickens have been emerging in the People's Republic of China. (cdc.gov)
- ALV-J was first isolated from meat-type chickens with myeloid leukosis in 1988. (cdc.gov)
- In chickens, endogenous Avian Leukosis Virus subgroup E (ALVE) expression has been associated with reductions in muscle growth rate and egg production, as well as providing the potential for novel recombinant viruses. (unboundmedicine.com)
- In chickens, however, there is a large class of endogenous retroviruses, members of the ERVK group, that are related to the replication-competent avian sarcoma-leukosis viruses (ASLV). (asm.org)
- Meng, Fanfeng;Li, Qiuchen;Zhang, Yubiao;Cui, Zhizhong;Chang, Shuang;Zhao, Peng 2018-07-11 00:00:00 Abstract There was an outbreak of hemangioma associated with avian leukosis virus subgroup J (ALV-J) between 2006 and 2010 in China in commercial layer chickens. (deepdyve.com)
- Subgroups A, B, E and J are the major subgroups of avian leukosis virus (ALV) infecting chickens. (biomedcentral.com)
- Avian leukosis virus (ALV) is an economically important poultry pathogen and its infection may result in low productivity and tumor mortality in chickens. (biomedcentral.com)
- HPRS-103, the prototype of avian leukosis virus (ALV) subgroup J, was isolated in 1989 from meat-type chickens from commercial flocks where it induces myelocytic myeloid leukosis (ML). The HPRS-103 env gene differs considerably from other ALV subgroups but shows high identity (75-97%) to env-like sequences of the different members of the EAV family of endogenous avian retroviruses. (microbiologyresearch.org)
- Avian leukosis virus (ALV) is a retrovirus which causes the development of several different kinds of benign and malignant neoplasms (tumors) in chickens worldwide. (poultrydvm.com)
- Lymphoid leukosis is caused by an avian retrovirus that induces a lymphoblastic lymphosarcoma in susceptible chickens, four months of age or older. (poultrydvm.com)
- There is no treatment for Avian Leukosis and affected chickens are best put to sleep. (chickenvet.co.uk)
- You will find other associated issues surrounding Avian Leukosis as infected birds often act as a reservoir for other diseases, such as Respiratory Disease, which can go on to infect other chickens who have not transmitted Avian Leukosis. (chickenvet.co.uk)
- This research includes tissue tropism of avian leukosis virus subgroup J (ALV-J) in congenitally infected broiler chickens using an immunohistochemistry (IHC) technique detecting gp85 viral glycoprotein. (uga.edu)
- Under natural conditions, lymphoid leukosis has been the most common form of the leukosis/sarcoma group of diseases seen in chicken flocks, although in the 1990s myeloid leukosis become prevalent in meat-type chickens. (merckvetmanual.com)
- Lymphoid leukosis occurs naturally only in chickens. (merckvetmanual.com)
- Isolates that can induce lymphoid leukosis in chickens are commonly called avian leukosis viruses and are divided into subgroups A, B, C, D, and J, on the basis of differences in their viral envelope glycoproteins, which determine antigenicity, viral interference patterns with members of the same and different subgroups, and host range. (merckvetmanual.com)
- The Avian Leukosis Virus p27 Antigen test kit will determine the presence of the p27 antigen of the Avian Leukosis Virus in chickens. (biochek.com)
- It affects chickens worldwide with susceptibility varying considerably among different strains and types of stock - egg layers are generally more susceptible to lymphoid leukosis. (elsitioavicola.com)
- Avian leukosis virus (ALV) infection, shedding, and tumors in maternal ALV antibody-positive and -negative chickens exposed to virus at hatching. (docphin.com)
- Chickens highly susceptible to avian leukosis virus (ALV) infection and tumors, with and without ALV subgroup A maternal antibody (MAB), were infected with a field strain of ALV subgroup A at hatching. (docphin.com)
- Multicentric histiocytosis related to avian leukosis virus subgroup J (ALV-J)-infection in meat-type local chickens. (omicsdi.org)
- Avian leukosis virus subgroup J (ALV-J) was first isolated from meat-type chickens in 1988. (omicsdi.org)
- Avian leukosis virus (ALV) is an oncogenic virus causing a variety of neoplasms in chickens. (usda.gov)
- The group of avian leukosis virus in chickens contains six closely related subgroups, A to E and J. The prevalence of ALVs in hosts may have imposed strong selection pressure toward resistance to ALV infection, and chickens have evolved resistance to infection by the ALVs. (usda.gov)
- Methods: 140-day-old female chickens of White Recessive Rock (WRR) were confirmed as J subgroup avian leukosis virus (ALV-J) infection. (omicsdi.org)
- The E26 avian retrovirus causes an acute leukemia in chickens and transforms both myeloid and erythroid cells. (nih.gov)
- The presence of endogenous viruses may reduce the immune response to related pathogenic exogenous retroviruses, increasing the likelihood of disease, as demonstrated in chickens with avian leukosis or sarcoma virus infection ( 53 ). (asm.org)
- Induction of lymphomas in the bursa of Fabricius of chickens by replication competent, non-transforming avian retroviruses (Avian Leukosis Virus, ALV) is both an economically significant, naturally occurring disease and an experimental model system which has provided seminal insights into the role of the myc oncogene in B-cell neoplasia. (springer.com)
- Enrietto PJ, Payne LN, Hayman MJ (1983) A recovered avian myelocytomatosis virus that induces lymphomas in chickens: Pathogenic properties and their molecular basis. (springer.com)
- Previous studies of Eastern equine encephalitis virus in Ring-necked Pheasants (Phasianus colchicus) and avian leucosis virus in domestic chickens (Gallus gallus) found virus in feather pulp up to 7 days beyond detection in blood (10-12). (thefreedictionary.com)
- Characterization of endogenous avian leukosis viruses in chicken embryonic fibroblast substrates used in production of measles and mumps vaccines. (greenmedinfo.com)
- Receptor specificity in avian sarcoma and leukosis viruses (ASLV) maps to the central region of the envelope surface protein, SU. (semanticscholar.org)
- The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily. (semanticscholar.org)
- A soluble form of a receptor for subgroup A avian leukosis and sarcoma viruses (ALSV-A) blocks infection and binds directly to ALSV-A. (semanticscholar.org)
- The receptor for the subgroup A avian leukosis-sarcoma viruses binds to subgroup A but not to subgroup C envelope glycoprotein. (semanticscholar.org)
- The avian leukosis viruses (ALVs) are a major group of retroviruses associated with neoplastic diseases in poultry. (pirbright.ac.uk)
- Avian leukosis virus belongs to a family of viruses called retroviruses. (chickenvet.co.uk)
- In this family of viruses are bovine leukosis (affecting cattle), feline leukosis (affecting cats) and HIV. (chickenvet.co.uk)
- The International Committee on Taxonomy of Viruses has designated avian leukosis virus as the type species within the Alpharetrovirus genus of the family Retroviridae . (merckvetmanual.com)
- Detection of the major antigen (p27) present in the core of leukosis/sarcoma viruses forms the basis of several diagnostic tests. (merckvetmanual.com)
- these viruses have not been isolated from other avian species except pheasants, partridges, and quail. (merckvetmanual.com)
- Endogenous leukosis viruses are part of the chicken genome and are transmitted genetically. (hendrix-genetics.com)
- Exogenous leukosis viruses are transmitted as infectious virus particles. (hendrix-genetics.com)
- Low freqeuncy production of recombinant subgroup E avian leukosis viruses by uninfected V-15B chicken cells. (fhcrc.org)
- Three new erbB transducing viruses generated during avian leukosis virus-induced erythroblastosis have been cloned and sequenced, and their transforming abilities have been analyzed. (elsevier.com)
- The subgroup J avian leukosis viruses (ALV-J), which induce erythroblastosis and myelocytomatosis, have the greatest pathogenicity and transmission ability within this class of viruses. (beds.ac.uk)
- The subgroup J avian leukosis viruses (ALV-J), which induce erythroblastosis and myelocytomatosis, have a greater pathogenicity and transmission ability than the other subgroups. (beds.ac.uk)
- Pigs have long been considered potential intermediate hosts in which avian influenza viruses can adapt to humans. (cdc.gov)
- No infected pig had influenza-like symptoms, indicating that influenza A (H5N1) viruses can replicate undetected for prolonged periods, facilitating avian virus adaptation to mammalian hosts. (cdc.gov)
- Although wild birds, the natural hosts, seldom become sick when infected, avian influenza viruses can cause disease in domestic poultry and, rarely, in human beings. (thefreedictionary.com)
- Upon expression of TVA, these cells are capable of binding viruses with the envelope protein of avian sarcoma/leukosis virus subtype A ( ASLV-A ). These cTVA mice may be useful for infection by retroviruses, rabies virus, and other viruses with ASLV-A glycoproteins. (jax.org)
- Differential host gene expression in cells infected with highly pathogenic H5N1 avian influenza viruses. (semanticscholar.org)
- Avian genomics and the innate immune response to viruses. (semanticscholar.org)
- Neiman P, Payne LN, Weiss RA (1980b) Viral DNA in bursal lymphomas induced by avian leukosis viruses. (springer.com)
- INTRODUCTION Avian leukosis virus (ALV) is an oncogenic retrovirus causing neoplastic diseases, such as lymphocytoma, myeloid leukosis, and hemangioma, as well as immunosuppression (Fadly and Smith, 1999). (deepdyve.com)
- Since the initial isolation of subgroup J avian leukosis virus in England, the virus has been isolated from broiler-breeder stocks that experience myeloid neoplasms (myelocytoma) in many other countries. (merckvetmanual.com)
- Myeloid leukosis diagnosed in a backyard flock, with ALV 'J strain' isolated. (thepoultrysite.com)
- We are using avian leukosis virus (ALV) receptor interactions as a model system to understand how retroviruses enter their host cells. (pnas.org)
- Occupational exposure to poultry and prevalence of antibodies against Marek's disease virus and avian leukosis retroviruses. (bmj.com)
- We have analyzed the placement of sites of integration of avian sarcoma-leukosis virus (ASLV) and human immunodeficiency virus (HIV) DNA in the draft chicken genome sequence, with the goals of assessing species-specific effects on integration and allowing comparison to the distribution of chicken endogenous retroviruses (ERVs). (asm.org)
- Phylogenetic analysis of the sequences showed the evolutionary relationships of the isolates with HPRS-103 and the EAV family of endogenous avian retroviruses. (microbiologyresearch.org)
- Lymphoid leukosis is caused by certain members of the leukosis/sarcoma group of avian retroviruses. (merckvetmanual.com)
- The U3 sequences of 84.2% (16/19) of the ALV-J layer isolates displayed less than 92.5% sequence homology to those of the ALV-J broiler isolates, although the transcriptional regulatory elements that are typical of avian retroviruses were highly conserved. (omicsdi.org)
- The entry process of the avian sarcoma and leukosis virus (ASLV) family of retroviruses requires first a specific interaction between the viral surface (SU) glycoproteins and a receptor on the cell surface at a neutral pH, triggering conformational changes in the viral SU and transmembrane (TM) glycoproteins, followed by exposure to low pH to complete fusion. (mendeley.com)
- Avian sarcoma leukosis virus is characterized by a wide range of tumors, the most common of which are lymphomas. (wikipedia.org)
- Wang, Xiaomei 2016-07-20 00:00:00 Avian leukosis virus (ALV) is an avian oncogenic retrovirus that can induce various clinical tumors. (deepdyve.com)
- Avian leukosis virus (ALV) is an oncogenic virus, an infectious disease causing tumors in poultry. (hendrix-genetics.com)
- Histopathology, immunohistochemistry or fluorescent antibody tests to detect viral antigen in the tumors are needed to differentiate between Marek's disease virus (MDV), reticuloendotheliosis virus (REV) and avian leucosis virus. (hendrix-genetics.com)
- Avian leukosis virus (ALV) is a retrovirus that causes tumors in avian species, and its vertical and horizontal transmission in poultry flocks results in enormous economic losses. (biomedcentral.com)
- Lymphoid leukosis is the most common form of this disease and with typical presentation of gradual onset, persistent low mortality, and neoplasia of the bursa. (wikipedia.org)
- Lymphoid leukosis has a worldwide distribution, and is most commonly found in birds 16 weeks or older. (wikipedia.org)
- Lymphoid leukosis was eradicated in primary breeders in the 1980s and 1990s which dramatically reduced the incidence of the disease in commercial laying hens. (wikipedia.org)
- In Lymphoid Leukosis, especially, there may be abdominal enlargement. (barnhealth.com)
- Lymphoid leukosis is a neoplastic disease of poultry caused by avian leukosis virus. (merckvetmanual.com)
- Hayward WS, Neel B, Astrin SM (1981) Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. (springer.com)
Subgroup B avian leuko1
- We now report a significant improvement made to this viral targeting method by using a related bridge protein, designated TVB-EGF, comprised of the extracellular domain of the TVB receptor for subgroup B avian leukosis virus fused to epidermal growth factor (EGF). (pnas.org)
- However, the movement was unsuccessful in maintaining leukosis-free flocks. (wikipedia.org)
- Whilst we are all very familiar with Mareks disease causing tumours in chicken flocks, Avian Leukosis is another tumour causing virus that can have equally devastating effects. (chickenvet.co.uk)
- As much as 1.5% excess mortality per week has been reported in commercial broiler-breeder flocks naturally infected with subgroup J avian leukosis virus. (merckvetmanual.com)
- Twenty-eight broiler breeder flocks were tested for avian leukosis virus (ALV) group-specific (gs) antigen shedding into the albumen. (mysciencework.com)
- Approximately 25 per cent of Q3 avian diagnostic submissions were from game bird flocks and two-thirds from chicken flocks. (thepoultrysite.com)
- Molecular epidemiology of avian leukosis virus subgroup J in layer flocks in China. (omicsdi.org)
- The solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virus. (nih.gov)
- The cellular receptor for subgroup A avian leukosis and sarcoma virus (ALSV-A) is Tva, which contains a motif related to repeats in the low density lipoprotein receptor (LDLR) ligand binding repeat (LBr) and which is necessary for viral entry. (nih.gov)
- Role of basic residues in the subgroup-determining region of the subgroup A avian sarcoma and leukosis virus envelope in receptor binding and infection. (semanticscholar.org)
- Evolutionary pressure of a receptor competitor selects different subgroup a avian leukosis virus escape variants with altered receptor interactions. (semanticscholar.org)
- Novel monoclonal antibody directed at the receptor binding site on the avian sarcoma and leukosis virus Env complex. (semanticscholar.org)
- Analysis of the subgroup A avian sarcoma and leukosis virus receptor: the 40-residue, cysteine-rich, low-density lipoprotein receptor repeat motif of Tva is sufficient to mediate viral entry. (semanticscholar.org)
- Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor. (semanticscholar.org)
- Receptor-induced conformational changes in the subgroup A avian leukosis and sarcoma virus envelope glycoprotein. (semanticscholar.org)
- The bridge protein tested was comprised of the low density lipoprotein receptor-related extracellular domain of the TVA receptor for subgroup A avian leukosis virus (ALV-A) fused to human epidermal growth factor (EGF). (pnas.org)
- Despite the discovery of specific host receptors that are critical for ALV entry, there has been only one report on the acquisition of resistance to ALV subgroup C in avian species via genome editing of host receptor genes. (biomedcentral.com)
- Avian leukosis virus (ALV) has been used as a model system to understand the mechanism of pH-independent viral entry involving receptor-induced conformational changes in the viral envelope (Env) glycoprotein that lead to membrane fusion. (nih.gov)
- COMMA-1D cells were engineered to express the avian leukosis subtype A receptor, tv-a, to permit infection by recombinant avian leukosis virus produced by the replication-competent avian splice vector, RCAS. (aacrjournals.org)
- The cTVA transgene contains the human ubiquitin C ( UBC ) promoter driving expression of a loxP -flanked destabilized green fluorescent protein (GFP) and polyadenylation sequence, followed by an avian specific retroviral receptor (TVA) gene derived from quail. (jax.org)
- The cTVA transgene in this strain carries the human ubiquitin C ( UBC ) promoter/enhancer elements driving expression of a loxP -flanked destabilized green fluorescent protein (GFP) and polyadenylation sequence, followed by an avian specific retroviral receptor (TVA) gene derived from quail. (jax.org)
- Transgenic avians having a recombinant ovomucoid gene expression controlling region operably linked to one or more useful amino acid coding sequences. (google.com)
Endogenous avian leuko2
- Lack of evidence of endogenous avian leukosis virus and endogenous avian retrovirus transmission to measles, mumps, and rubella vaccine recipients. (clinicalnews.org)
- Western blot antibody reactivity of chicken sera to endogenous avian leukosis virus (ALV) (Rous-associated virus 0) antigen. (cdc.gov)
Resistance to avian leuko1
- Maas HJL, Debber GF, Groenend JE (1982) Age-related resistance to avian-leukosis virus. (springer.com)
- The subgroups evolved to utilize difference cellular receptors to gain entry into avian cells due to the host developing resistance to viral entry. (wikipedia.org)
- These results suggest that CRISPR/Cas9-mediated genome editing can be used to efficiently modify avian cells and establish novel chicken cell lines with resistance to viral infection. (biomedcentral.com)
- 5. The transgenic avian of claim 4 , wherein the vector is selected from the group consisting of a plasmid, a viral vector, and an artificial chromosome. (google.com)
- Burmester BR, Fontes AK, Walter WG (1960) Pathogenicity of a viral strain (RPL 12) causing avian visceral lymphomatosis and related neoplasms. (springer.com)
- 9. The transgenic avian of claim 1 , wherein the transgenic avian is a chicken or a quail. (google.com)
- Avian Leukosis is a neoplastic disease caused by the (aptly named) Avian Leukosis virus (ALV). (everything2.com)
- 2011). From 2007 to 2010, hemangioma was the most hazardous neoplastic disease associated with ALV-J, which caused a massive pandemic and became a major avian health concern. (deepdyve.com)
- BackgroundAvian leukosis virus ALV is a major infectious disease that impacts the poultry industry worldwide. (duhnnae.com)
- The very mention of the words Avian Influenza (AI) or Bird Flu strikes fear into the hearts of poultry keepers and the general public alike. (poultrykeeper.com)
- Avian leukosis virus (ALV) is one of the main causes of tumour development within the poultry industry in China. (beds.ac.uk)
- Avian leukosis virus (ALV) is one of the major causes of disease in poultry, and commonly produces tumours in those infected. (beds.ac.uk)
- The Avian Health Program offers diagnostic testing, consultation and extension services for commercial and backyard poultry producers. (cornell.edu)
- Dr. Jarra Jagne , head of the Avian Health program and veterinarian specializing in poultry, a diplomate of the American College of Poultry Veterinarians, is available for disease, nutrition, health, and management consultation. (cornell.edu)
- The Avian Health Program also provides support for meeting the requirements of the National Poultry Improvement Program (NPIP) and for exports. (cornell.edu)
- This invention relates to the construction of a genetically engineered vector which would be useful as a vaccine against poultry diseases or for ferrying desirable genes into the avian system. (patentgenius.com)
- Recombination between two different subgroups of avian leukosis virus can occur in field conditions and cause economic losses. (merckvetmanual.com)
- Cleavage of either 9 or 12 amino acids from the carboxyl terminus creates two mature CA species, named CA2 and CA3, that can be detected in avian sarcoma/leukemia virus (R. B. Pepinsky, I. A. Papayannopoulos, E. P. Chow, N. K. Krishna, R. C. Craven, and V. M. Vogt, J. Virol. (uthscsa.edu)
- Historically, close contact of fowl with humans has been shown epidemiologically to foster cross-species jump (avian to human) of new influenza strains (e.g. (thefreedictionary.com)
Retrovirus that can induce1
- Avian leukosis virus subgroup J (ALV-J) is an avian retrovirus that can induce myelocytomas. (bvsalud.org)
- By inoculation of blood samples in DF-1 (C/E) cell culture, an exogenous avian leukosis virus (ALV) strain SDAU09C2 was isolated from a breeder farm of Chinese native breed 'Luhua' in Shandong province. (bvsalud.org)
- Avian leukosis virus (ALV) subgroup J is thought to have emerged through a recombination event between an unknown exogenous ALV and the endogenous retrovirus elements designated EAV-HP. (omicsdi.org)
- Avian leukosis virus subgroup J was identified by an immunofluorescence assay with monoclonal antibody JE9, whereas Marek's disease virus or reticuloendotheliosis virus was not detected. (deepdyve.com)
- Antigenic variants of J subgroup avian leukosis virus: sequence analysis reveals multiple changes in the env gene. (microbiologyresearch.org)
- Reply to commentary by D. Elleder and J. Hejnar on the article "Avian sarcoma and leukosis virus gag gene in the Anser anser domesticus genome" published in Genetics and Molecular Research 14 (4): 14379-14386 to the letter published in Genet. (geneticsmr.com)
- Some of them contained antigens of avian leukosis virus (ALV) by immunohistochemistry,and the env gene of ALV subgroup J was detected from the spleens by polymerase chain reaction (PCR). (omicsdi.org)
- Selection of reference genes for gene expression analysis by real-time qPCR in avian cells infected with infectious bronchitis virus. (semanticscholar.org)
- 9. The DNA of claim 5 wherein said foreign DNA sequence is an avian gene capable of being amplified concurrent with formation of concatemers by said amplicon. (patentgenius.com)
- The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. (nih.gov)
- A highly specific ELISA for detection of Avian Leukosis Virus antigen, used in eradication programs. (biochek.com)
- Actually, endogenous avian sarcoma and leukosis virus (enASLV) sequences are variable in the Galliformes birds, and geese have split with chicken for a long time. (geneticsmr.com)
- If you suspect any of your birds have Avian Leukosis disease then seek veterinary help immediately. (chickenvet.co.uk)
- The only means of control when avian influenza has been observed in a flock of domestic fowl is destruction of infected birds and disinfection of the farm. (thefreedictionary.com)
- 2000. Cospeciation and horizontal transmission of avian sarcoma and leukosis virus gag genes in galliform birds. (tolweb.org)
- ResultsIn this study, the avian leukosis virus subgroup J ALV-J proviral genome, including the gag genes, were treated as targets for RNAi. (duhnnae.com)
- In addition to piRNAs that protect the germ-line genome from transposon activation, mammals and avian produce a distinct and abundant set of non-repetitive piRNA sequences whose function is unknown. (rochester.edu)
- Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events. (asm.org)
- Like Mareks disease Avian Leukosis infects the white blood cells, these are the cells that the body uses to fight infections, which leads to two main affects. (chickenvet.co.uk)
- However, it is important to note, that unlike Mareks disease Avian Leukosis never causes nervous signs as the virus will never causes tumours in the nervous system. (chickenvet.co.uk)
- Newcastle disease was first found in Newcastle-upon-Tyne in 1926.The disease is caused by a virus called Avian Paramyxovirus Type 1. (poultrykeeper.com)
- Newcastle disease together with Avian Influenza (Bird Flu) is a notifiable disease in the UK. (poultrykeeper.com)
- Polymerase chain reaction for detection of avian leucosis virus subgroup J in feather pulp. (thefreedictionary.com)
- The avian leukosis virus sequences found in the measles vaccine are in intact virions, as DNA treatment of the vaccines did not prevent their detection by polymerase chain reaction (PCR). (clinicalnews.org)
- The retrovirus avian leukosis virus was found in the measles vaccine, but at a very low level (700 nucleotides from 4 sequence reads). (clinicalnews.org)
- The formation of the mature carboxyl terminus of CA in avian sarcoma/leukemia virus is the result of a sequence of cleavage events at three PR sites that lie between CA and NC in the Gag polyprotein. (uthscsa.edu)
- 1. A transgenic avian comprising a nucleic acid sequence encoding a heterologous protein operably linked to an ovomucoid promoter that is at least 95% identical to the nucleotide sequence of about 34,473 to about 36,248 of SEQ ID NO: 36, wherein the heterologous protein is produced in an oviduct cell of the avian. (google.com)
- 2. The transgenic avian of claim 1 , wherein the nucleic acid sequence comprises a signal sequence coding region. (google.com)
- 3. The transgenic avian of claim 1 , wherein the nucleic acid sequence comprises an IRES. (google.com)
- 4. The transgenic avian of claim 1 , wherein the nucleic acid sequence further comprises a vector. (google.com)
- 6. The transgenic avian of claim 1 , wherein the nucleic acid sequence further comprises a retrovirus vector. (google.com)
- 7. The transgenic avian of claim 1 , wherein the ovomucoid promoter comprises a nucleotide sequence that is at least 99% identical to the nucleotide sequence of about 34,473 to about 36,248 of SEQ ID NO: 36. (google.com)
- Diagnosis of bovine leukosis: ELISA, a new technique. (springer.com)