Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Drug Discovery: The process of finding chemicals for potential therapeutic use.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Drug Design: The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.Mice, Inbred C57BLModels, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Cell Line, Tumor: A cell line derived from cultured tumor cells.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Molecular Targeted Therapy: Treatments with drugs which interact with or block synthesis of specific cellular components characteristic of the individual's disease in order to stop or interrupt the specific biochemical dysfunction involved in progression of the disease.Nanostructures: Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Small Molecule Libraries: Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening analysis of the gene function, protein interaction, cellular processing, biochemical pathways, or other chemical interactions.Schizonts: Multinucleate cells or a stage in the development of sporozoan protozoa. It is exemplified by the life cycle of PLASMODIUM FALCIPARUM in the MALARIA infection cycle.Proteomics: The systematic study of the complete complement of proteins (PROTEOME) of organisms.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.MicroRNAs: Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.Host-Pathogen Interactions: The interactions between a host and a pathogen, usually resulting in disease.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Bioengineering: The application of engineering principles and methods to living organisms or biological systems.Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.Biological Evolution: The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.RNA Interference: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Forecasting: The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Proteome: The protein complement of an organism coded for by its genome.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.HEK293 Cells: A cell line generated from human embryonic kidney cells that were transformed with human adenovirus type 5.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Oxidative Stress: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.High-Throughput Screening Assays: Rapid methods of measuring the effects of an agent in a biological or chemical assay. The assay usually involves some form of automation or a way to conduct multiple assays at the same time using sample arrays.Systems Biology: Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Epigenomics: The systematic study of the global gene expression changes due to EPIGENETIC PROCESSES and not due to DNA base sequence changes.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.Genetic Therapy: Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.Stem Cells: Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.Metabolic Networks and Pathways: Complex sets of enzymatic reactions connected to each other via their product and substrate metabolites.Microscopy, Fluorescence: Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.Epigenesis, Genetic: A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.Graphite: An allotropic form of carbon that is used in pencils, as a lubricant, and in matches and explosives. It is obtained by mining and its dust can cause lung irritation.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Gene Regulatory Networks: Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.Peptides: Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Protein Transport: The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport.Transcriptome: The pattern of GENE EXPRESSION at the level of genetic transcription in a specific organism or under specific circumstances in specific cells.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cell Death: The termination of the cell's ability to carry out vital functions such as metabolism, growth, reproduction, responsiveness, and adaptability.Nuclear Magnetic Resonance, Biomolecular: NMR spectroscopy on small- to medium-size biological macromolecules. This is often used for structural investigation of proteins and nucleic acids, and often involves more than one isotope.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Life Cycle Stages: The continuous sequence of changes undergone by living organisms during the post-embryonic developmental process, such as metamorphosis in insects and amphibians. This includes the developmental stages of apicomplexans such as the malarial parasite, PLASMODIUM FALCIPARUM.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.Ligands: A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)Cell Membrane: The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Nanotubes, Carbon: Nanometer-sized tubes composed mainly of CARBON. Such nanotubes are used as probes for high-resolution structural and chemical imaging of biomolecules with ATOMIC FORCE MICROSCOPY.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Microscopy, Atomic Force: A type of scanning probe microscopy in which a probe systematically rides across the surface of a sample being scanned in a raster pattern. The vertical position is recorded as a spring attached to the probe rises and falls in response to peaks and valleys on the surface. These deflections produce a topographic map of the sample.Breast Neoplasms: Tumors or cancer of the human BREAST.Nanotechnology: The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Translational Medical Research: The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Bacterial Physiological Phenomena: Physiological processes and properties of BACTERIA.Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Green Fluorescent Proteins: Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.Receptors, G-Protein-Coupled: The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.Central Nervous System: The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.History, 20th Century: Time period from 1901 through 2000 of the common era.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Down-Regulation: A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Gastrointestinal Tract: Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Regenerative Medicine: A field of medicine concerned with developing and using strategies aimed at repair or replacement of damaged, diseased, or metabolically deficient organs, tissues, and cells via TISSUE ENGINEERING; CELL TRANSPLANTATION; and ARTIFICIAL ORGANS and BIOARTIFICIAL ORGANS and tissues.Epithelial Cells: Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.Environment: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.Transplantation, Heterologous: Transplantation between animals of different species.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Induced Pluripotent Stem Cells: Cells from adult organisms that have been reprogrammed into a pluripotential state similar to that of EMBRYONIC STEM CELLS.Gene Knockdown Techniques: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.Protein Interaction Maps: Graphs representing sets of measurable, non-covalent physical contacts with specific PROTEINS in living organisms or in cells.Genetic Engineering: Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc.Protein Engineering: Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.Public Policy: A course or method of action selected, usually by a government, from among alternatives to guide and determine present and future decisions.Protein Folding: Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Gene Knockout Techniques: Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.Recombinant Fusion Proteins: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Sirtuin 1: A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Mass Spectrometry: An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.Gene Targeting: The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.Reactive Oxygen Species: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.Neovascularization, Pathologic: A pathologic process consisting of the proliferation of blood vessels in abnormal tissues or in abnormal positions.Crystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.Immune System: The body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components.Cluster Analysis: A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.Genome-Wide Association Study: An analysis comparing the allele frequencies of all available (or a whole GENOME representative set of) polymorphic markers in unrelated patients with a specific symptom or disease condition, and those of healthy controls to identify markers associated with a specific disease or condition.Protein Processing, Post-Translational: Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.Stem Cell Transplantation: The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.Amyloid beta-Peptides: Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Animals, Genetically Modified: ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.Tumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.United StatesMyelin Sheath: The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Protein Multimerization: The assembly of the QUATERNARY PROTEIN STRUCTURE of multimeric proteins (MULTIPROTEIN COMPLEXES) from their composite PROTEIN SUBUNITS.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.Host-Parasite Interactions: The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.Immunity, Innate: The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.Nerve Tissue ProteinsRecombinant Proteins: Proteins prepared by recombinant DNA technology.Homeostasis: The processes whereby the internal environment of an organism tends to remain balanced and stable.Immunotherapy: Manipulation of the host's immune system in treatment of disease. It includes both active and passive immunization as well as immunosuppressive therapy to prevent graft rejection.Intercellular Signaling Peptides and Proteins: Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.Autophagy: The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.Gene Silencing: Interruption or suppression of the expression of a gene at transcriptional or translational levels.Neuronal Plasticity: The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.Drug Evaluation, Preclinical: Preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications.Bacterial Proteins: Proteins found in any species of bacterium.Protein Interaction Mapping: Methods for determining interaction between PROTEINS.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Stress, Physiological: The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Cell Culture Techniques: Methods for maintaining or growing CELLS in vitro.Regeneration: The physiological renewal, repair, or replacement of tissue.Genetic Vectors: DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.Tandem Mass Spectrometry: A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.T-Lymphocytes: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Cricetulus: A genus of the family Muridae consisting of eleven species. C. migratorius, the grey or Armenian hamster, and C. griseus, the Chinese hamster, are the two species used in biomedical research.Health Promotion: Encouraging consumer behaviors most likely to optimize health potentials (physical and psychosocial) through health information, preventive programs, and access to medical care.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Genetic Variation: Genotypic differences observed among individuals in a population.Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Cell Lineage: The developmental history of specific differentiated cell types as traced back to the original STEM CELLS in the embryo.Models, Immunological: Theoretical representations that simulate the behavior or activity of immune system, processes, or phenomena. They include the use of mathematical equations, computers, and other electrical equipment.Ecosystem: A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Polymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.Retinal Pigment Epithelium: The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.Extracellular Matrix: A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.Tissue Engineering: Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.Plants: Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.Microarray Analysis: The simultaneous analysis, on a microchip, of multiple samples or targets arranged in an array format.Behavior, Animal: The observable response an animal makes to any situation.Mice, Inbred BALB CMicroscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Neoplastic Stem Cells: Highly proliferative, self-renewing, and colony-forming stem cells which give rise to NEOPLASMS.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Microscopy, Electron, Transmission: Electron microscopy in which the ELECTRONS or their reaction products that pass down through the specimen are imaged below the plane of the specimen.
The band has spawned other groups such as Copperfield...Avenue...Agatha Brooke....PW Blues Band ...Sorge Brothers Band...and ...
Ulmann, E.F. (July 2010). "Between the Covers". Avenue. Retrieved September 2, 2016. Official website. ...
870 Park Avenue, altered in 1976-with John S. Hagmann Bel Air, California Residence RAMSA's residential practice has expanded ... Hawthorne, Christopher (October 2, 2013). "Grand Avenue Project: Uncertainty Could be a Good Thing". Los Angeles Times. Kim, ... Stephens, Suzanne (December 1989). "The Architectural Mouseketeers". Avenue. Miller, Ross. "Euro Disneyland and the Image of ... completed in 2012 and 520 Park Avenue, currently under construction. Tribeca Park, 400 Chambers Street, New York City ( ...
"Avenue". The Skyscraper Center. CTBUH. Retrieved July 15, 2017. "Avenue". Emporis. Retrieved July 15, 2017. "Avenue". ... Along with Avenue. Along with Ascent Uptown. Any buildings that have been topped out but are not completed are also included. ...
Mineo, Mike (November 1, 2006). "Luke Haines returns with Off My Rocker at the Art School Bop". Avenue. Retrieved January 30, ...
Menachem Av) - [the Hebrew month of] Menachem Av מנחת חינוך, מנ״ח (Minchat Chinuch) - lit. Meal-Offering of Education; a ... See also א״א אב בית דין, אב״ד (av beit din) - leader of the court; lit. father of the house of judgment. See also ב״ד אב בית ... The Beginning of Wisdom (Psalms 111:10) רחוב, רח׳ (rechov) - (Modern Hebrew) street; road; avenue; drive; way; boulevard רב ... the ninth of Av; the anniversary of the destruction of the first and second Temples in Jerusalem י״ג] תיקוני דיקנא, [י״ג] ת״ד ...
The neighbourhood is bordered by the Bow River to the north and east, 16 Avenue to the south, and Stoney Trail to the west. The ... His parents opened riding stables on Chinook (now 34th.) Avenue. Of note also was the use of a large field near the park, the ...
Bridge Lions Moving to West LRT". Avenue. Archived from the original on 7 April 2014. Retrieved 1 April 2014. "Centre Street ... The lower deck connects Riverfront Avenue in Chinatown with Memorial Drive, while the upper elevated deck crosses Memorial ...
"Alumni news" (PDF). Avenue. University of Glasgow (50): 18. June 2011. Retrieved 14 January 2017. Evans, Rebecca (24 October ...
Russell agreed to buy the collection and represent Kieselstein-Cord at Jensen's U.S. flagship store on Madison Avenue in New ... Avenue. January 1999. Missing or empty ,title= (help) "Search the Collections: Barry Kieselstein-Cord". The Metropolitan Museum ... Saks Fifth Avenue, Henri Bendel, and Bonwit Teller among others). Among these retailers was Lou Lattimore in Dallas, TX, where ...
"AVENUE". Official Charts Company. Retrieved 14 April 2010. "LEONA LEWIS". Official Charts Company. Retrieved 14 April 2010. ...
ISBN 1-895086-16-7. Olafson, Karin (February 2016). "The Life and Legacy of Katie Ohe and Harry Kiyooka". Avenue. Retrieved 27 ...
"Avenue". Retrieved 2007-12-27. "Avenue". Retrieved 2007-12-31. "400 South Tryon". ...
Avenue". The Washington Post. p. B5 ; Hsu, Spencer S. (March 22, 2001). "Pennsylvania Avenue Opening Gets New Push". The ... It supported a 1995 plan by Mayor Marion Barry to spend $2 billion improving New York Avenue NE, efforts to build a local ... White, Jean (June 16, 1964). "Aquarium Goes to Potomac Park, With Span Planned to Maine Ave". The Washington Post. p. B1. "D.C ... Fehr, Stephen C. (July 31, 1995). "N.Y. Avenue's Future Faces a Rough Road". The Washington Post. p. C1 ; Fehr, Stephen C. ( ...
... which the Army referred to as the VZ-9-AV (with AV standing for "Avro," an unusual departure from normal U.S. Army nomenclature ... Avro VZ-9-AV Avrocar at the Paul E. Garber Preservation, Restoration and Storage Facility, National Air and Space Museum c.1984 ... The first Avrocar, S/N 58-7055 (marked AV-7055), after tethered testing, became the "wind tunnel" test model at NASA Ames, ... The Avrocar S/N 58-7055 (marked AV-7055) on its rollout. ...
A podium was built at the end of the 700-metre (0.43-mile) avenue. On the podium were slogans, "Russia will be free" and "This ... The resulting large attendance at the protest was not expected, and resulted in a traffic jam in a nearby Kutozovsky Avenue.[9] ... The two largest protest actions in December 2011 took place on Bolotnaya Square (10 December) and Academician Sakharov Avenue ( ... There were large follow-up demonstrations 24 December including a rally "For Fair Elections" at Academician Sakharov Avenue in ...
Audio and video (AV) equipment connections historically were analog one-way, single-purpose and point-to-point. Even digital AV ... IEEE 802.1Qav - Traffic shaping for AV streams[edit]. In order to provide professional AV services, the AVB architecture ... 2.2 IEEE 802.1Qav - Traffic shaping for AV streams *2.2.1 Tagging requirements at the stream source and the bridge ... This bounded buffer size is a key attribute that enables bounded delay and eliminates network congestion for admitted AV ...
Woodson Ave., Sacramento[74]. Sacramento 28. Thursday, November 10, 1977. 3:00 a.m. La Riviera Dr. near Watt Ave., Sacramento[ ... Madison and Main Ave., Orangevale. Sacramento 18. Friday, April 15, 1977. 2:30 a.m. Madison and Manzanita Avenues, Crestview[66 ... Robertson and Whitney Ave., Sacramento[63]. Sacramento 16. Friday, March 18, 1977. 10:45 p.m. Rancho Cordova[64][65]. ... Winding Way, east of Walnut Ave., Sacramento[78][79]. Sacramento 31. Thursday, February 2, 1978. 9:00 p.m. Rancho Cordova[80][ ...
Garland Avenue house[edit]. Ossian H. Sweet House at 2905 Garland. Dr. Sweet was more educated than many white men in the ...
The project plan of the Nezalezhnastci Avenue ensemble is a good example. The layout provided for the main features of the town ... The urban architectural ensemble of Nezalezhnastci Avenue in Minsk is an example of the integrated approach in organizing a ... At present buildings which form the Nezalezhnastci Avenue ensemble are inscribed on the State List of Historical and Cultural ... "Architectural ensemble of Francysk Scaryna avenue in Minsk (1940's −1950's) - UNESCO World Heritage Centre". ...
Severe bradycardia or advanced AV block[edit]. Unless a pacemaker is present, beta-blockers can severely depress conduction in ... the AV node, resulting in reduction of heart rate and cardiac output. Usage of beta-blockers in tachycardic patients with Wolff ...
Park Avenue Elementary School[edit]. On February 9, 2000, the Los Angeles Weekly published an article about the environmental ... troubles of Park Avenue Elementary School.[73] Ellen Ochoa Learning Center[edit]. This list is incomplete; you can help by ...
... and Hamid Dabashi (March 2009). "Sal-e No Mobarak!". Tehran Avenue. Archived from the original on 2 February 2014 ...
"First Avenue". First Avenue. "Soundcloud". Soundcloud. Desoplex Records. Bennet, Tony. "Duluth Tribune". Duluth Tribune. Duluth ...
"Top 10 Holdings, Third Avenue Focused Credit Fund". Third Avenue. May 31, 2015. "U.S. Energy Secretary Speaks On Clean Energy ... and Third Avenue.[dead link] SNL Financial reported April 21, 2016, on Longview's 155 days of continuous operation during which ...
The original Georgia Avenue was the road now named Potomac Avenue in Southwest and Southeast. Current-day Georgia Avenue was ... 1908 appropriations bill ended up changing the name of Georgia Avenue to Potomac Avenue and Brightwood Avenue to Georgia Avenue ... Georgia Avenue begins north of Florida Avenue, which was the boundary of the Old City, and is a continuation of 7th Street. ... Seventh Street Pike was built as a plank road from Boundary Avenue (now Florida Avenue) to the District Line in 1852.[2] Being ...
... is a team of children, parents, staff and community members who are respectfully challenged to achieve ...
Second Avenue Subway Newsletter. February 2013. Retrieved June 9, 2013.. *^ a b c d e f g h "Second Avenue Subway Final ... T train continues down Second Avenue (Phase 3) 55th Street 55th Street & 2nd Avenue 3 4 ​6 ,6, ​ E ​M trains via proposed ... 23rd Street & 2nd Avenue 3 M15 SBS (southbound only), M23 SBS East Village 14th Street 14th Street & 2nd Avenue 3 L train via ... Houston-3rd Streets & 2nd Avenue 3 F ,F, ​ trains via proposed transfer at Second Avenue[note 3]. M15 (southbound only). ...
Temporary Bus Stop Closure: Mt Vernon Ave at Executive Ave, Jan 15 ... Minnesota Avenue. In accordance with WMATAs Joint Development Policies and Guidelines, a local jurisdiction may purchase ... In the case of WMATA property near the Minnesota Avenue Metro Station (Orange Line), the Government of the District of Columbia ... to develop a mixed-use development on a WMATA parking lot located at the intersection of Minnesota Avenue NE and Benning Road ...
Public Comments on Canoga Avenue Facility Documents. How to Submit Comments. Comments on Canoga Avenue Facility Documents can ... Special Exposure Cohort Petition Evaluation Report for Canoga Avenue Facility * Canoga Avenue Facility SEC Petition Evaluation ... the Canoga Avenue Facility (Vanowen Building), the Downey Facility, and the De Soto Avenue Facility (these are sometimes ... Canoga Avenue Facility SEC Petition Evaluation Report, Rev. 0 (January 1, 1955 to December 31, 1960) pdf icon[1 MB (97 pages)] ...
... this school was renamed Thurgood Marshall Elementary School instead of its original name Station Avenue School. It is scheduled ... Station Avenue School--Ashtabula, Ohio Due to its location in a highly black area of town, this school was renamed Thurgood ... Marshall Elementary School instead of its original name Station Avenue School. It is scheduled to be closed and razed soon. ...
See an archive of all second avenue stories published on the New York Media network, which includes NYMag, The Cut, Vulture, ... As the Second Avenue Subway Opens, a Look at What We Didnt BuildA new book, Never Built New York, contains great ideas and ... First and Second Avenue Bus Lanes to Create Surface SubwayJanette Sadik-Khan announce big changes on the East Side yesterday. ...
Madison Avenue, Moscow. "Mikhail Gorbachev came to Geneva to field test the weaponry of pub-lic relations instead of the ... Madison Avenue Moscows queer idea that they could court the West with pub-lic forums was suddenly beginning to look insane. ... More:1980s1985Cold WarGeneva (Switzerland)Iron CurtainMadison AvenueMikhail GorbachevRonald ReaganSoviet UnionSummit ... For three days Kunst stood with a banner in the gray Geneva cold outside Madison Ave-nue Moscow, waiting patiently for a ...
Whole Foods Market Florida Avenue is your organic grocery store. Shop weekly sales and Amazon Prime member deals. Get delivery ... Florida Avenue Guests 60+, at high risk or with disabilities can shop in-store from 7 - 8 am on Mon, Wed and Fri. Face ... Events at Florida Avenue. Demos, happy hours and more: Theres always something new happening at your store. ...
Georgia Avenue took a step toward revitalization yesterday with the groundbreaking of a $28 million residential and retail ... Two other mixed-use projects - Georgia Commons at 3910 Georgia Ave. NW and Park Place being built over the Georgia Avenue- ... the Residences at Georgia Avenue would be one of the largest mixed-used projects on Georgia Avenue in the past two decades, ... The Georgia Avenue corridor is one of 20 neighborhoods Mr. Fenty and the D.C. Office of Planning have targeted for attracting ...
College Avenue Santa Rosa, CA $50 Per Month ... includes MULTIPLE SCOOPS. Multiple Facebook Page postings. Content upgraded ...
... problem is that the house I am renting is on Avenue, right by the polo fields (very close to the Outdoor Stage). If the map is ... Walking on Avenue 50.. So according to the Map, avenue 50 will be blocked off, problem is that the house I am renting is on ... Re: Walking on Avenue 50.. well you see where that ada parking is, find a way to hop a wall or get out close to that. ... Re: Walking on Avenue 50.. you can bike/walk north up Monroe to 49th no problem. The much dumber thing is no longer allowing ...
J Avenue. Owned and developed by Siam Future Development, J Avenue, at 88,000 square feet, is one of Thailands most ... Owned and developed by Siam Future Development, J Avenue, at 88,000 square feet, is one of Thailands most comprehensive ...
The Buick Park Avenue was redesigned for the 1997 model year and was discontinued after the 2005 model year. ... 1999 Buick Park Avenue moderate overlap test. Applies to 1997-2005 models ...
He kindly agreed to write up an introduction to Empire Avenue for Buzzfeed readers which Ive published below (modified ... My friend Alan from the social media stock market Empire Avenue has recently published an eBook introduction to the game. ... Walking Down Empire Avenue My friend Alan from the social media stock market Empire Avenue has recently published an eBook ... Have you been walking down Empire Avenue yet?. Empire Avenue is a popular web site that is part stock market game, part social ...
THE THIRD-AVENUE RAILROAD. Order Reprints, Todays Paper,Subscribe ...
Advisory Board and NIOSH Discussions on Battelle Laboratories - King Avenue. The Battelle Laboratories - King Avenue discussion ... Document Archive for Battelle Laboratories - King Avenue. Technical Documents. * Site Profile:. * Revised: March 26, 2010 pdf ... Site Profile for Battelle Memorial Institute, King Avenue and West Jefferson Sites, Columbus, Ohio, Rev. 01 pdf icon[5.6 MB ( ... 1090 Tusculum Avenue. Cincinnati, OH 45226. Please include the Site Profile/Docket Number (206) on all comments. ...
Book now at Avenue Grill - Denver in Denver, CO. Explore menu, see photos and read 1532 reviews: We havent been here in a ... The Avenue Grill offers free parking. Our private lot is located directly across the street from The Avenue Grill on the ... The Avenue Grill is the go to place for a nice lunch to a fancy dinner...I also appreciate that it is open all afternoon, if ... Hadnt been to Avenue Grill in years & its as good as I remember. Nice brunch menu & since we went early (10 am), it wasnt ...
Amityville residents should expect delays on Bayview Avenue today while new asphalt is laid, according to the village website. ... The repaving of the section of Bayview Avenue between Merrick Road and Oak Street is the villages second such project in 20 ... Amityville residents should expect delays on Bayview Avenue today while new asphalt is laid, according to the village website. ... years, after work was done on South Bayview Avenue last year.. Get the Newsday Now newsletter!. The best of Newsday every day ...
22 Acacia Avenue é uma canção da banda de heavy metal britânica Iron Maiden, presente no álbum The Number of the Beast.[1] A ... "Phantom of the Opera" · "Wrathchild" · "22 Acacia Avenue" · "Where Eagles Dare" · "Revelations" · "Powerslave" · "Rime of the ... Obtida de "" ...
This Business is not BBB Accredited. BUSINESS SERVICES (GENERAL) in Swanton, VT. See business rating, customer reviews, contact information and more.
ibis Nanjing Avenue General Hotel. Economy hotel for business and leisure Kita Katsuta West Commercial Street, West by General ...
Discover genuine guest reviews for Park Avenue Changi along with the latest prices and availability - book now. ... Book the Park Avenue Changi - Stay at this 3.5-star business-friendly hotel in Singapore. Enjoy free WiFi, an outdoor pool, and ... Can I cancel my reservation for free at Park Avenue Changi and receive a full refund? Yes, Park Avenue Changi offers free ... Where is Park Avenue Changi located? Situated in Singapore, this hotel is within a 10-minute walk of Singapore Expo and Changi ...
Lobbyists representing Avenue Solutions, 2008:. Year: 2008. ") 2007. ") 2006. ") 2004. ") Total number of lobbyists: 1. Total ...
Online marketing firm Avenue A is gearing up to go head-to-head against the big players in online advertising, through a new ... Avenue A Gunning for Industry Leaders. By Christopher Saunders , April 23, 2001 Page 1 of 1 ... For instance, Avenue As president and chief executive Brian McAndrews said a lack of tools for planning, automated buying, ... Its new operating division, Atlas DMT, aims to license Seattle-based Avenue As software to ad agencies and in-house media ...
  • GENEVA - The Russians called their Mission in Geneva "Madison Avenue, Moscow" and won-dered aloud if an American Express card in Raisa Gorbachev's hand would change the world. (
  • If you asked the typical HR leader how the flashy glitz of Madison Avenue and the world of consumer advertising fit into their job function, you'd probably get more than a few raised eyebrows. (
  • To improve communications targeting health issues, a bit of perspective from Madison Avenue can help. (
  • Primary Sources at Gagosian, Madison Avenue embraces Artschwager's challenge to viewers. (
  • This website explores the complex relationships between modern medicine and modern advertising, or 'Madison Avenue,' as the latter is colloquially termed. (
  • The Medicine and Madison Avenue Project presents images and database information for approximately 600 health-related advertisements printed in newspapers and magazines. (
  • With bus rapid transit coming to Penn Avenue in 2016, community partners are hoping to leverage public investment to bring economic development to a north Minneapolis corridor sprinkled with vacant properties. (
  • The Buick Park Avenue was redesigned for the 1997 model year and was discontinued after the 2005 model year. (
  • In the case of WMATA property near the Minnesota Avenue Metro Station (Orange Line), the Government of the District of Columbia purchased approximately 7.8 acres of land in 2002. (
  • Two other mixed-use projects - Georgia Commons at 3910 Georgia Ave. NW and Park Place being built over the Georgia Avenue-Petworth Metrorail Station - are key components of the city's redevelopment plans for Georgia Avenue. (
  • Members of the Minneapolis City Council's Transportation and Public Works Committee disagreed with the decision to route bikes off of Penn Avenue because bike lanes are included there in the city's long-term bike plan. (
  • But questions about the city's two largest shopping centers and the Rainier Avenue cross-town connector revealed differences. (
  • St. Paul's annual first rite of summer takes place along the city's historic Grand Avenue. (
  • Elizabeth's rich authentic cultural vibe draws its residents and tourists to the city's' heart of its local businesses and entertainment districts like Elizabeth Avenue. (
  • A 25-year-old Glenview man was arrested on the 4500 block of Lilac Avenue on Jan. 9 at 5 p.m. and charged with criminal damage to property over $300 after an investigation into an incident that occurred on Nov. 19 on the 800 block of Milwaukee Avenue. (
  • The original Georgia Avenue was the road now named Potomac Avenue in Southwest and Southeast. (
  • The 1908 appropriations bill ended up changing the name of Georgia Avenue to Potomac Avenue and Brightwood Avenue to Georgia Avenue. (
  • A few years later, he got his wish: Georgia became Potomac Avenue, and Brightwood Avenue-stretching from the northern boundary of the L'Enfant City through the old plantations of Petworth and the Civil War battlegrounds of Fort Stevens up to the Maryland border-became Georgia. (
  • WHDH interviews the owner of the M&R convenience store on Shawmut Avenue, where his employee, a recent immigrant from Bangladesh, who came here in search of an education was shot in the head Tuesday night. (
  • The Washington Evening Star also editorialized against the bill again, saying that changing the name of Brightwood Avenue "would remove all local significance from the name" and confuse those living in the neighborhood around what was then Georgia Avenue. (
  • This project will bring much-needed affordable housing, healthy shopping alternatives and jobs to the Georgia Avenue-Petworth neighborhood," said Adrian G. Washington , principal in the Neighborhood Development Co., which is the developer and is headquartered across the street from the Residences at Georgia Avenue. (
  • The Avenue is a favored lunch and dinner destination among the uptown Denver business crowd, as well as a popular neighborhood bar and grill. (
  • Grandville Avenue Arts and Humanities (GAAH) provides two safe havens for learning: the Cook Library Center (formerly the Grandville Avenue Neighborhood Library) and the Cook Arts Center (formerly the Grandville Avenue Academy for the Arts. (
  • Administering the programs of the Cook Arts Center and the Cook Library Center, our mission of transforming lives in the Grandville Avenue neighborhood through reading and the arts and by celebrating the community's cultural richness is played out every day through the programs and services that we offer. (
  • Endeavoring to address the needs in the Grandville Avenue neighborhood surrounding gang-activity, housing, and inadequate municipal services on behalf of the materially poor and marginalized, GAAH invested with other community organizations, churches, and businesses to build and staff a Neighborhood Library, and an Arts Academy, to assist children and adults of the Grandville Avenue neighborhood in having a safe environment in which to pursue reading, study, and the arts. (
  • The Grandville Avenue Neighborhood Library, located at 1260 Grandville Avenue SW, opened its doors in the fall of 1996. (
  • Since the original library opened more than 4,000 library cards have been issued to youth and adults of the Grandville Avenue neighborhood. (
  • Children who reside or attend school in the Grandville Avenue neighborhood are able to take classes for free. (
  • Major intersections are Lyell Avenue , Emerson Street , Lexington Avenue , Driving Park Avenue , Seneca Parkway , Ridgeway Avenue , and Ridge Road West . (
  • If you are using social media to drive traffic to your content, why not try Empire Avenue now? (
  • Æthelwold , sønn av Alfreds eldre bror Æthelred , og således berettiget til tronen, gjorde et forsøk på å ta makten, men ble drept i slaget ved Holme i 902 . (
  • I 1679 kom Titus Oates ' avsløringer av en påstått katolsk sammensvergelse, pavekonspirasjonen , som utløste etterfølgerkrisen da det ble avslørt at Karls bror og antatte arving, Jakob Stuart, hertug av York , var katolikk. (
  • Krisen førte til dannelsen av to politiske partier, whigene , «jordbrukspartiet», som kjempet for at kongens bror som katolikk ikke kunne arve tronen, og toryene , «hoffpartiet», som var imot å utelukke kongens bror selv om han var katolikk. (
  • Kongen var på linje med toryene og som følge av avsløringen om Rye House-komplottet om å myrde både Karl og hans bror i 1683 ble en del ledere hos whigene enten drept eller tvunget til å rømme til utlandet. (
  • Agencies are expressing a strong interest in a complete digital marketing management system that can help them successfully navigate the complexity of digital marketing," said Atlas DMT's new president, Tom Sperry, who joined Avenue A in 1999, after serving as managing partner for Bozell Worldwide and CF2GS. (
  • Æthelstan var en av de mest fromme av de vestsaksiske konger, og var kjent for å samle relikvier og grunnlegge kirker. (
  • Mellom 2 to18 prosent av amerikanske barn antas å bli berørt av ADHD og Ritalin, et sentralstimulerende lik amfetamin og kokain, er fortsatt en av de mest forskrevne medisiner for de atferdsmessige lidelse. (
  • Fairview Avenue is one of Goleta's main thoroughfares today. (
  • Located directly on 5th Avenue South (the main street in Olde Naples) and only 1-1/2 blocks from the beach! (
  • OTTAWA - Kaladar Avenue has been shut indefinitely between Gregg Street and Heron Road to fix a broken water main. (
  • Durango Fire Protection District firefighters responded to a report of smoke at the Old Post Office building about 1:30 p.m. Thursday in the 1000 block of Main Avenue. (
  • The 1000 block of Main Avenue was closed early Thursday afternoon while Durango Fire Protection District firefighters looked for the cause of smoke in the Old Post Office building. (
  • La Plata County employees were evacuated for about an hour Thursday afternoon as Durango Fire Protection District firefighters looked for the cause of smoke in the Old Post Office building in the 1000 block of Main Avenue. (
  • Vestsakserne greide å kjempe tilbake under Alfred (som siden fikk tilnavnet «den store»), og han oppnådde en avgjørende seier i slaget ved Edington . (
  • På 890-tallet ble nye vikingangrep med hell slått tilbake av Alfred, støttet av hans sønn (og Æthelstans far) Edvard og Æthelred , herre av mercianerne. (
  • En ting var klart: 3 måneder etter at rottene sluttet å motta Ritalin, dyrenes neurochemistry stor grad hadde besluttet tilbake til forbehandling tilstand. (
  • En politisk krise kom etter Cromwells død i 1658 som resulterte i at monarkiet til sist ble gjeninnført, og Karl ble invitert til å komme tilbake til Storbritannia. (
  • [ trenger referanse ] Karl lovte å gjeninnføre religiøs frihet for katolikker og protestantiske dissentere med hans kongelige erklæring om overbærenhet ( Declaration of Indulgence ) av 1672 , men det engelske parlament tvang ham til å trekke den tilbake. (
  • The Government of the District of Columbia solicited a developer, Donatelli Development and Blue Skye Development, to develop a mixed-use development on a WMATA parking lot located at the intersection of Minnesota Avenue NE and Benning Road NE. (
  • Paradise Road provides access to McCarran International Airport (south of the Tropicana Avenue and Paradise Road intersection) and SR 593 serves as the southern end of the University of Nevada, Las Vegas campus (including the Thomas & Mack Center). (
  • MAP OF THE AVENUE This map provides address numbers at each intersection, guiding you to locate businesses found in the following directory. (
  • Crossing the intersection at University Ave. and Queen is like looking at two sides of a coin at once. (
  • For the subway station at Houston Street, see Second Avenue (IND Sixth Avenue Line) . (
  • The Second Avenue Subway (internally referred to as the IND Second Avenue Line by the MTA and abbreviated to SAS ) is a New York City Subway line that runs under Second Avenue on the East Side of Manhattan . (
  • In anticipation of the Second Avenue Subway being built to replace them, parallel elevated lines along Second Avenue and Third Avenue were demolished in 1942 and 1955, respectively, despite several factors causing plans for the Second Avenue Subway to be cancelled. (
  • As the Second Avenue Subway Opens, a Look at What We Didn't Build A new book, Never Built New York , contains great ideas and awful ones. (
  • Trains on the CTA Blue Line were stopped this afternoon after smoke was reported in the tunnel of the Milwaukee Avenue subway near Division. (
  • WASHINGTON , Feb. 5, 2019 /PRNewswire/ -- Fannie Mae (FNMA/OTCQB) priced its first credit risk transfer transaction of the year, Connecticut Avenue Securities ® (CAS) Series 2019-R01, a $960 million note offering that represents Fannie Mae's second CAS REMIC™ transaction. (
  • Kong Håkon fikk en kristen oppdragelse av sin formynder, og forsøkte forgjeves å innføre kristendommen i Norge. (
  • Ingen annen vestsaksisk konge spilte en slik aktiv rolle i europeisk politikk som Æthelstan, til og med i Norge , og sørget for ekteskap for flere av sine søstre til herskere i europeiske stater. (
  • Han var sønn av kong Edvard den eldre og hans første hustru Ecgwynn. (
  • Karls hustru, Katarina av Braganza , fødte ingen barn, men Karl anerkjente minst 12, kanskje 14, uektefødte barn med flere forskjellige kvinner. (
  • Where it crosses Colesville Road a mile into Maryland , Georgia Avenue splits off U.S. Route 29 and becomes Maryland State Highway 97 . (
  • Owned and developed by Siam Future Development, J Avenue, at 88,000 square feet, is one of Thailand's most comprehensive lifestyle centers. (
  • Present landmarks along the avenue include the equestrian statue of Frederick II the Great (1851), the State Library, the State Opera House, several new ministries, the Russian embassy (1951), and the Humboldt University of Berlin (formerly Berlin University). (
  • The project at 4100 Georgia Ave. NW results from a decade of planning and legal wrangling to redevelop the area along the street, which consists now of primarily low- and middle-income residences and small stores. (
  • Grab a seat on the patio at the new restaurant at 3301 Georgia Ave. NW, order a few small plates and a drink, and take in your surroundings. (
  • The house is situated sideways on the lot because it was designed originally for a lot in downtown St. Paul, the site of the current Roy Wilkins Auditorium, and when Dr. Cornelius Williams decided to build on Summit Avenue instead, in what previously had been part of an apple orchard, he turned the house sideways rather than having the architect redesign it to better fit the lot. (
  • Current-day Georgia Avenue was originally named 7th Street Extended and Brightwood Avenue. (
  • While Senator Bacon's proposal did not come to fruition, Wisconsin's senator John Coit Spooner offered the same proposal again in 1907, which also included changing the name of 16th Street to Washington Avenue. (
  • The full Second Avenue Line, if and when it is funded, will be built in three more phases to eventually connect Harlem-125th Street in Harlem to Hanover Square in Lower Manhattan. (
  • The repaving of the section of Bayview Avenue between Merrick Road and Oak Street is the village's second such project in 20 years, after work was done on South Bayview Avenue last year. (
  • Welcome to Georgia Avenue, the street that's eternally on the cusp. (
  • The beach, 5th Avenue South, 3rd Street and the world famous Naples Pier are the most popular attractions in Olde Naples. (
  • Easy walking distance from all of the shops and restaurants on both 5th Avenue South and 3rd Street as well as the pier (where you can see dolphins swimming idly by while fishermen cast their lines from several stories above the water's surface). (
  • When we found this place right on 5th Avenue South, within easy walking distance of all of the shops and restaurants on both 5th Avenue South and Third Street and less than a 2 minute walk from the beach we knew that we ***had*** to have it. (
  • Motorists should follow posted detour onto Flushing Avenue westbound, make a right onto Navy Street, take a left onto Sands Street and follow to the BQE on-ramp. (
  • WALK Grand Avenue can be accessed from any street on foot. (
  • On-street parking is available along Grand Avenue at no charge - be mindful of signage indicating parking guidelines. (
  • Boston firefighters are at 300 Shawmut Ave., at Waltham Street, for a fire on the fifth floor. (
  • The victim was found unconscious inside a convenience store at 718 Shawmut Ave. at Williams Street around 9:10 p.m. (
  • A car crashed into several other cars on Shawmut Avenue near Lenox Street shortly after 10 p.m. (
  • Shortly before 2 p.m. on West Springfield Street between Shawmut Avenue and Washington Street. (
  • Boston Police report arresting a woman they say used a broken bottle to slash two people at Shawmut Avenue and Ball Street around 9:35 p.m. (
  • To avoid Lake, take St. Paul Street from downtown to Driving Park Avenue Bridge and cross over to Dewey Avenue. (
  • From Lyell Avenue north to Emerson Street it forms the border between Lyell-Otis and Edgerton , then becomes Edgerton entirely. (
  • Edgerton Park - Bordered by Backus Street, Bloss Street, and Dewey Ave. (
  • Dewey Avenue enters the Town of Greece at Eastland Road and Studley Street. (
  • The whole team at the ibis Paris Avenue d'Italie wishes you a warm welcome to their hotel located at the heart of a vibrant area, on Place d'Italie in the 13th district. (
  • The ibis Paris Avenue d'Italie 13ème hotel is located 6.2 miles (10 km) from Orly and 109 yards (100 m) from Place d'Italie, where 3 metro lines connect you to the whole of Paris, from the Eiffel Tower to La Défense, and the Italie Deux shopping center is just a short walk from the hotel. (
  • Close to the Austerlitz, Montparnasse and Gare de Lyon train stations, the ibis Paris Avenue d'Italie enjoys a privileged and easy-to-access location. (
  • The mixed-use development called Residences at Georgia Avenue is one of three real estate projects the D.C. Council hopes will attract new business and housing to the corridor between downtown Washington and the Maryland suburbs. (
  • When completed near the end of 2008, the Residences at Georgia Avenue would be one of the largest mixed-used projects on Georgia Avenue in the past two decades, covering 94,443 square feet. (
  • From 311 this morning comes two reports of yellow Stars of David being spraypainted on front doors of residences on Shawmut Avenue between West Newton and West Concord streets. (
  • Starting just north of the Silver Spring station, the Washington Metro Red Line runs roughly parallel to Georgia Avenue. (
  • This part runs parallel to Lake Avenue and is connected to it by many small side streets. (
  • A new grocery store, a large thrift shop, self-storage facilities and renovations to a hotel and restaurant all were approved along Milwaukee Avenue in Glenview - the latest steps forward in a plan to improve the major thoroughfare. (
  • Fifteen years later, in 1889, the county of Santa Barbara officially dedicated the thoroughfare as a public county road, named Fairview Avenue. (
  • Dewey Avenue is the major thoroughfare of several city neighborhoods. (
  • Residents and travelers alike enjoy strolling with family, shopping, dining at our unique restaurants, meeting their friends for coffee, or simply spending an afternoon running errands along the avenue. (
  • NBC Boston reports officials shut a polling place at the Haynes House, 735 Shawmut Ave. this afternoon after white powder spilled out of an absentee ballot. (
  • Og i 'forhøyede-plus labyrint' og 'åpne felt' tester, undersøkte rotter i voksen alder tre måneder etter seponering av medikamentet viste færre tegn på angst i forhold til ubehandlet gnagere. (
  • I så fall er det mulig at kronisk bruk av stoffet ville endre hjernens kjemi og atferd godt inn i voksen alder. (
  • Within the District of Columbia and a short distance in Silver Spring, Maryland , Georgia Avenue is also U.S. Route 29 . (
  • Dewey Avenue in the city is a dense, urban, mixed commercial-residential route. (
  • The Georgia Avenue corridor is one of 20 neighborhoods Mr. Fenty and the D.C. Office of Planning have targeted for attracting more retail business to Washington , instead of letting suburbs get the shoppers and their sales tax revenue. (
  • Seven years ago, the village of Glenview adopted the Milwaukee Avenue Corridor Plan, a vision of Milwaukee Avenue as a gateway into Glenview. (
  • Decades before it was a corporate corridor, a restaurant mecca or automobile dealership row, Milwaukee Avenue from Wheeling north was a ribbon of quiet country road. (
  • So according to the Map, avenue 50 will be blocked off, problem is that the house I am renting is on Avenue, right by the polo fields (very close to the Outdoor Stage). (
  • Park Avenue Fertility goes out of their way to establish close connections with their patients, providing not only comprehensive fertility care, but also much-needed emotional support. (
  • But sources close to the brawls have told us that there is simply no where else to brawl in the city of Edmonton, so Whyte Ave has just become a default brawl zone. (
  • The plan called for a tree-lined avenue, easy to navigate on bike or foot and with a mix of land uses. (
  • PEDAL Over 140 new bike parking spaces have been installed along Grand Avenue! (
  • The Business Men's Association also opposed the bill, saying it opposed the renaming of any avenue that was named in the original plan of the city. (
  • For the bus line that runs on Second Avenue, see M15 (New York City bus) . (
  • We're sorry, but Courtyard by Marriott Philadelphia City Avenue is temporarily unavailable. (
  • Bruk av oppmerksomhet Deficit / Hyperactivity Disorder (ADHD) stoffet Ritalin med små barn kan føre til langsiktige endringer i utviklingen av hjernen, antyder en ny studie av svært unge rotter av et forskerteam ved Weill Cornell Medical College i New York City. (
  • Avenue Calgary is a city lifestyle magazine that brings readers the best of the city. (
  • Beginning the morning of Monday, April 29th, 2013, the City of Fort Walton Beach began a project to remove and replace failing corrugated metal stormwater pipe within the right of way in-between 332 and 335 Victoria Avenue NW. (
  • The project calls for widening Milwaukee Avenue in Libertyville, and has been underway for almost a year. (
  • Therefore, it comes as no surprise that this year Dr. Levi and his Park Avenue Fertility clinic, established in 2005 in Connecticut, have earned the highest recognition for demonstrating superior outcomes in treating patients struggling with infertility. (
  • Hispanic Heritage Month in the Elizabeth Avenue Partnership Special Improvement District runs from September 15th to October 15th each year. (
  • This Study Guide consists of approximately 21 pages of chapter summaries, quotes, character analysis, themes, and more - everything you need to sharpen your knowledge of The Prisoner of Second Avenue. (
  • Sheridan Morley, in his review of the play for Spectator , writes that The Prisoner of Second Avenue deals with a moment in history when not only the central character but Manhattan itself was on the brink of a total nervous collapse. (
  • More summaries and resources for teaching or studying The Prisoner of Second Avenue . (
  • The Prisoner of Second Avenue from BookRags . (
  • Georgia Avenue ends at the boundary with Howard County , where it becomes Roxbury Mills Road. (
  • The Elizabeth Avenue Partnership (EAP) will host a Hispanic Heritage Month Lunchtime Concert Series sponsored, in part by a HEART Grant (History, Arts, Education Reaching Thousands), working with local restaurants to promote the cultural diversity and authentic Hispanic heritage of the area. (
  • RIDE The 63 line Metro Transit buses stop at most corners along Grand Avenue heading east and west. (
  • Due to its location in a highly black area of town, this school was renamed Thurgood Marshall Elementary School instead of its original name Station Avenue School. (
  • In addition to their office in Trumbull, CT Park Avenue Fertility has recently opened another convenient location in Fairfield to accommodate the growing demand for their services. (
  • More than half of the most influential small business people on Twitter (as determined by Dun & Bradstreet) have Empire Avenue accounts - most of them also have the highest Klout scores on that list . (
  • When run, Trojan:BAT/Killav.AV opens the banking trojan that it is bundled with in the RAR file. (
  • Intelligent, funny, and heartfelt, Primates of Park Avenue lifts a veil on a secret, elite world within a world-the exotic, fascinating, and strangely familiar culture of privileged Manhattan motherhood. (
  • Park Avenue Fertility and Dr. Andrew Levi of Connecticut were selected as a Fertility Center of Excellence for 2011 in recognition of outstanding results achieved in the fertility field. (
  • Park Avenue Fertility provides a wide spectrum of fertility services and treatments, ranging from In Vitro Fertilization , Surrogacy and Egg Donation to less common procedures. (
  • More information about Park Avenue Fertility can be obtained on their website at , or by calling Dr. Andrew Levi's offices in Fairfield (203-254-6000) and Trumbull (203-372-6700). (
  • The Park Avenue is large and luxurious, Buick's flagship. (
  • Though the Park Avenue is dated, it is a solid sedan, offering some of the latest technology for safety, convenience and communication from General Motors. (
  • Equipped with a supercharged V6 engine, the top-level Park Avenue Ultra is fast, stable and satisfying to drive. (
  • Two models are available: Park Avenue and Park Avenue Ultra. (
  • Park Avenue ($33,590) comes with a 205-horsepower 3.8-liter V6 engine. (
  • Park Avenue Ultra ($38,100) really moves with a 240-horsepower supercharged version of the 3.8-liter V6. (
  • A Prestige Package ($1692) adds many Ultra luxuries (but not the supercharger) to the base Park Avenue. (
  • StabiliTrak ($495) and OnStar are also available as options on the base Park Avenue. (
  • It enters Maplewood at Driving Park Avenue . (
  • The Grandville Avenue Academy for the Arts, located at 644 Grandville Avenue SW, opened in June of 2001 and was renamed the Cook Arts Center in December of 2008. (
  • The village has hired a team of consultants and appointed a committee made up of officials, business owners and residents to focus on making improvements along Milwaukee Avenue in southwest Glenview. (
  • Æthelstan beseiret dem i det avgjørende slaget ved Brunanburh , en seier som ga ham stor prestisje både på De britiske øyer og på det europeiske fastlandet. (
  • Every June, Washington holds the D.C. Caribbean Carnival, which includes a parade down the lower portion of Georgia Avenue, an area that is home to many Caribbean immigrants. (
  • Planners hope that pedestrians and bikers in Libertyville will have an easier time crossing Milwaukee Avenue and accessing other path networks in the area as part of a $23 million project by the Illinois Department of Transportation on the road. (
  • Last May's tornado in north Minneapolis may have accelerated the redevelopment already occurring at Penn Avenue North and West Broadway Avenue - a blighted area that officials hope could someday become like 50th and France or other key Minneapolis retail hubs. (
  • Tropicana Avenue is a major east-west section line arterial in the Las Vegas area. (
  • Alfred og den norrøne høvdingen Guthrum inngikk en fredsoverenskomst hvor Alfred tok vestlige Mercia mens østlige Mercia ble en del av norrøne East Anglia. (
  • Cromwell ble den ubestridte enehersker av England, Skottland og Irland mens Karl tilbrakte de ni neste årene i landflyktighet i Frankrike , De forente Nederlandene og i spanske Nederlandene. (
  • In 1906, Georgia's senator Augustus Octavius Bacon was so dismayed that Georgia Avenue had become so neglected that he proposed to rename it Navy Yard Avenue and at the same time change the name of Brightwood Avenue to Georgia Avenue. (
  • Please inform 5 Liamina Avenue Apartment in advance of your expected arrival time. (
  • Tiffany is embarking on a dramatic renovation of its Michigan Avenue store in an effort to keep the iconic jewelry brand shining. (
  • 939 ) var konge av angelsakserne fra 924 til 927 , en tittel etablert av Alfred den store , og konge av englenderne fra 927 til 939 . (
  • På midten av århundret kom England under et økende antall angrep fra norrøne vikinger , kulminert med invasjonen av den store hedenske hæren i 865 . (
  • A Lynn man already behind bars for a violent armed robbery in Brockton now faces charges for a shooting inside a Shawmut Avenue convenience store on July 14 in which the clerk was shot in the head even after handing money from the register, the Suffolk County District Attorney's office reports. (
  • The article " Great Ocean Explorers, Tobacco, Locomation And A Good Sign For AV Progress " discussed the positive implications of using the convoying concept for logistics. (
  • Empire Avenue is a popular web site that is part stock market game, part social network and all about meeting and connecting with some really great people. (
  • These communities are now part of the 35th Avenue Site. (
  • The avenue was the site of mass rallies during the East German period. (