Autonomic Nervous System
Autonomic Nervous System Diseases
Central Nervous System
Parasympathetic Nervous System
Sympathetic Nervous System
Nervous System
Ganglionic Blockers
Autonomic Denervation
Vagus Nerve
Autonomic Pathways
Autonomic Agents
Galvanic Skin Response
Autonomic Nerve Block
Arrhythmia, Sinus
Cardiovascular Physiological Processes
Electrocardiography
Electrocardiography, Ambulatory
Central Nervous System Diseases
Enteric Nervous System
Atropine
Trimethaphan
Peripheral Nervous System
Dysautonomia, Familial
Propranolol
Cardiovascular System
Baroreflex
Cardiovascular Physiological Phenomena
Brain
Hexamethonium
Parasympatholytics
Circadian Rhythm
Muscarinic Antagonists
Parasympathectomy
Central Nervous System Neoplasms
Ganglia, Autonomic
Norepinephrine
Glycopyrrolate
Chlorisondamine
Massage
Arrhythmias, Cardiac
Neurons
Pancreatic Polypeptide
Adrenergic Agents
Oxymetazoline
Nervous System Physiological Phenomena
Shy-Drager Syndrome
Bradycardia
Cardiography, Impedance
Dogs
Neurosecretory Systems
Adrenergic beta-Antagonists
Tilt-Table Test
Peripheral Nerves
Vagus Nerve Stimulation
Central Nervous System Infections
Respiration
Signal Processing, Computer-Assisted
Hemodynamics
Neuroimmunomodulation
Magnetocardiography
Telemetry
Epinephrine
Head-Down Tilt
Pressoreceptors
Sympathectomy
Arousal
Heart Rate, Fetal
Nervous System Diseases
Nervous System Neoplasms
Analysis of Variance
Respiratory Rate
Heart Conduction System
Hypotension, Orthostatic
Reflex
Adrenergic Antagonists
Ganglia, Sympathetic
Hexamethonium Compounds
Hypothalamus
Ganglionic Stimulants
Rats, Wistar
Sympathetic Fibers, Postganglionic
Electroacupuncture
Reflex, Abnormal
Splanchnic Nerves
Rats, Sprague-Dawley
Disease Models, Animal
Sympathomimetics
Refractory Period, Electrophysiological
Saliva
Hypertension
Hydrocortisone
Phentolamine
Respiratory Mechanics
Brain Stem
Cholinergic Agents
Central Nervous System Viral Diseases
Stress, Physiological
Paraganglioma
Respiratory Physiological Phenomena
Adrenergic alpha-Antagonists
Immunohistochemistry
Receptors, Adrenergic
Isoflurane
Spinal Cord
Cardiac Output
Skin Physiological Phenomena
Vagotomy
Hypothalamo-Hypophyseal System
Diabetic Neuropathies
Sleep
Anxiety
Hypoglycemia
Neurotransmitter Agents
Case-Control Studies
Pituitary-Adrenal System
alpha-Amylases
Death, Sudden
Vasculitis, Central Nervous System
Anesthesia
Tachycardia
Urinary Bladder
Death, Sudden, Cardiac
Gastrointestinal Tract
Neuroglia
Hypotension
Hormones
Syncope, Vasovagal
Atrial Fibrillation
Fourier Analysis
3-Iodobenzylguanidine
Neuropeptide Y
Central Nervous System Agents
Wakefulness
Insulin
Isoproterenol
Electroencephalography
Dose-Response Relationship, Drug
Irritable Bowel Syndrome
Trauma, Nervous System
Homeostasis
Myelin Sheath
Gene Expression Regulation, Developmental
Halothane
Mice, Transgenic
Sinoatrial Node
Central Nervous System Fungal Infections
Electrophysiology
Glucagon
Phenylephrine
Aging
Vibration
Receptors, Nicotinic
Acetylcholine
Adaptation, Physiological
Signal Transduction
Electrophysiologic Techniques, Cardiac
Exercise
Sex Characteristics
In Situ Hybridization
Models, Biological
Receptors, Muscarinic
Molecular Sequence Data
Reference Values
Myocardial Ischemia
Emotions
Pain
Skin
Electromyography
Nonlinear Dynamics
Astrocytes
Central autonomic activation by intracisternal TRH analogue excites gastric splanchnic afferent neurons. (1/2230)
Intracisternal (ic) injection of thyrotropin-releasing hormone (TRH) or its stable analogue RX 77368 influences gastric function via stimulation of vagal muscarinic pathways. In rats, the increase in gastric mucosal blood flow evoked by a low ic dose of RX 77368 occurs via release of calcitonin gene-related peptide from capsaicin-sensitive afferent neurons, most probably of spinal origin. In this study, the effect of low ic doses of RX 77368 on afferent impulse activity in splanchnic single fibers was investigated. The cisterna magna of overnight-fasted, urethan-anesthetized Sprague-Dawley rats was acutely cannulated, and fine splanchnic nerve twigs containing at least one fiber responsive to mechanical probing of the stomach were isolated at a site immediately distal to the left suprarenal ganglion. Unit mechanoreceptive fields were encountered in all portions of the stomach, both superficially and in deeper layers. Splanchnic afferent unit impulse activity was recorded continuously during basal conditions and in response to consecutive ic injections of saline and RX 77368 (15-30 min later; 1.5 or 3 ng). Basal discharge rates ranged from 0 to 154 impulses/min (median = 10.2 impulses/min). A majority of splanchnic single units with ongoing activity increased their mean discharge rate by >/=20% after ic injection of RX 77368 at either 1.5 ng (6/10 units; median increase 63%) or 3 ng (19/24 units; median increase 175%). Five units lacking impulse activity in the 5-min before ic RX 77368 (3 ng) were also excited, with the onset of discharge occurring within 1.0-5.0 min postinjection. In units excited by ic RX 77368, peak discharge occurred 15.6 +/- 1.3 min after injection and was followed by a decline to stable activity levels +info)Pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2-(3H)-furylidene]-1,3-cyclopentanedione (oudenone). (2/2230)
The pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2(3H)-furylidene]-1,3-cyclopentanedione (oudenone) were studied in both anesthetized animals and isolated organs. Oudenone (10--40 mg/kg i.v.) induced an initial rise in blood pressure followed by a prolonged hypotension in the anesthetized rats. In unanesthetized spontaneously hypertensive rats (SHR), oudenone (5--200 mg/kg p.o.) caused a dose-related decrease in the systolic blood pressure. The initial pressor effect was diminished by pretreatments with phentolamine, guanethidine, hexamethonium and was abolished in the pithed rats. In addition, intracisternal administrations of oudenone (100--600 mug/kg) showed a marked increase in blood pressure in the anesthetized rats, suggesting that the pressor effect may be due to centrally mediated actions. Oudenone, given intra-arterially into the femoral artery (400--800 mug/kg), caused a long-lasting vasodilation in anesthetized dogs. At a relatively high dose (40 mg/kg i.v.), oudenone antagonized all pressor responses to autonomic agents and central vagus nerve stimulation in anesthetized rats and dogs, however, oudenone showed no anti-cholinergic,-histaminergic, beta-adrenergic and adrenergic neuron blocking properties. (+info)Differences in heart rate variability between young and elderly normal men during graded head up tilt. (3/2230)
An autoregressive spectral analysis of heart rate variability (HRV) was used to analyze the differences in autonomic functions during graded head up tilt (HUT) between young and elderly men. After recording at the 0 degree position, the table was rotated to an upright position. The incline of the table was increased progressively to 15 degrees, 30 degrees and 60 degrees. The data obtained from seven young subjects (mean age of 20.0 years) and nine elderly subjects (mean age of 63.3 years) were analyzed. The high frequency components expressed by normalized units (HFnu) were used as the parasympathetic indicators, and HFnu decreased with tilt angle in both age groups. These results suggested that parasympathetic withdrawal have an important role in adaptation to an upright posture in both age groups. However, mean HF amplitude at the 0 degree position in elderly men was not significantly different from that of young men at 60 degrees tilt. A significant interaction effect (age group x tilt angle) was found for mean HF amplitude. The increase of the low frequency components expressed by normalized units (LFnu) and the LF-to-HF ratio in elderly subjects from 0 degree to 15 degrees seemed to be larger than that in young subjects. Sympathetic activities may be sensitive to lower levels of orthostatic stress in the elderly, and the elderly workers are easily affected by a change in workload. Therefore, keeping the workload lower and constant may be recommended to avoid excessive sympathetic activation among the elderly. (+info)Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea. (4/2230)
BACKGROUND: The chemoreflexes are an important mechanism for regulation of both breathing and autonomic cardiovascular function. Abnormalities in chemoreflex mechanisms may be implicated in increased cardiovascular stress in patients with obstructive sleep apnea (OSA). We tested the hypothesis that chemoreflex function is altered in patients with OSA. METHODS AND RESULTS: We compared ventilatory, sympathetic, heart rate, and blood pressure responses to hypoxia, hypercapnia, and the cold pressor test in 16 untreated normotensive patients with OSA and 12 normal control subjects matched for age and body mass index. Baseline muscle sympathetic nerve activity (MSNA) was higher in the patients with OSA than in the control subjects (43+/-4 versus 21+/-3 bursts per minute; P<0. 001). During hypoxia, patients with OSA had greater increases in minute ventilation (5.8+/-0.8 versus 3.2+/-0.7 L/min; P=0.02), heart rate (10+/-1 versus 7+/-1 bpm; P=0.03), and mean arterial pressure (7+/-2 versus 0+/-2 mm Hg; P=0.001) than control subjects. Despite higher ventilation and blood pressure (both of which inhibit sympathetic activity) in OSA patients, the MSNA increase during hypoxia was similar in OSA patients and control subjects. When the sympathetic-inhibitory influence of breathing was eliminated by apnea during hypoxia, the increase in MSNA in OSA patients (106+/-20%) was greater than in control subjects (52+/-23%; P=0.04). Prolongation of R-R interval with apnea during hypoxia was also greater in OSA patients (24+/-6%) than in control subjects (7+/-5%) (P=0.04). Autonomic, ventilatory, and blood pressure responses to hypercapnia and the cold pressor test in OSA patients were not different from those observed in control subjects. CONCLUSIONS: OSA is associated with a selective potentiation of autonomic, hemodynamic, and ventilatory responses to peripheral chemoreceptor activation by hypoxia. (+info)Differential effects of defibrillation on systemic and cardiac sympathetic activity. (5/2230)
OBJECTIVE: To assess the effect of defibrillation shocks on cardiac and circulating catecholamines. DESIGN: Prospective examination of myocardial catecholamine balance during dc shock by simultaneous determination of arterial and coronary sinus plasma concentrations. Internal countershocks (10-34 J) were applied in 30 patients after initiation of ventricular fibrillation for a routine implantable cardioverter defibrillator test. Another 10 patients were externally cardioverted (50-360 J) for atrial fibrillation. MAIN OUTCOME MEASURES: Transcardiac noradrenaline, adrenaline, and lactate gradients immediately after the shock. RESULTS: After internal shock, arterial noradrenaline increased from a mean (SD) of 263 (128) pg/ml at baseline to 370 (148) pg/ml (p = 0.001), while coronary sinus noradrenaline fell from 448 (292) to 363 (216) pg/ml (p = 0.01), reflecting a shift from cardiac net release to net uptake. After external shock delivery, there was a similar increase in arterial noradrenaline, from 260 (112) to 459 (200) pg/ml (p = 0.03), while coronary sinus noradrenaline remained unchanged. Systemic adrenaline increased 11-fold after external shock (p = 0.01), outlasting the threefold rise following internal shock (p = 0.001). In both groups, a negative transmyocardial adrenaline gradient at baseline decreased further, indicating enhanced myocardial uptake. Cardiac lactate production occurred after ventricular fibrillation and internal shock, but not after external cardioversion, so the neurohumoral changes resulted from the defibrillation process and not from alterations in oxidative metabolism. CONCLUSIONS: A dc shock induces marked systemic sympathoadrenal and sympathoneuronal activation, but attenuates cardiac sympathetic activity. This might promote the transient myocardial depression observed after electrical discharge to the heart. (+info)Lateralized effects of medial prefrontal cortex lesions on neuroendocrine and autonomic stress responses in rats. (6/2230)
The medial prefrontal cortex (mPFC) is highly activated by stress and modulates neuroendocrine and autonomic function. Dopaminergic inputs to mPFC facilitate coping ability and demonstrate considerable hemispheric functional lateralization. The present study investigated the potentially lateralized regulation of stress responses at the level of mPFC output neurons, using ibotenic acid lesions. Neuroendocrine function was assessed by plasma corticosterone increases in response to acute or repeated 20 min restraint stress. The primary index of autonomic activation was gastric ulcer development during a separate cold restraint stress. Restraint-induced defecation was also monitored. Plasma corticosterone levels were markedly lower in response to repeated versus acute restraint stress. In acutely restrained animals, right or bilateral, but not left mPFC lesions, decreased prestress corticosterone levels, whereas in repeatedly restrained rats, the same lesions significantly reduced the peak stress-induced corticosterone response. Stress ulcer development (after a single cold restraint stress) was greatly reduced by either right or bilateral mPFC lesions but was unaffected by left lesions. Restraint-induced defecation was elevated in animals with left mPFC lesions. Finally, a left-biased asymmetry in adrenal gland weights was observed across animals, which was unaffected by mPFC lesions. The results suggest that mPFC output neurons demonstrate an intrinsic right brain specialization in both neuroendocrine and autonomic activation. Such findings may be particularly relevant to clinical depression which is associated with both disturbances in stress regulatory systems and hemispheric imbalances in prefrontal function. (+info)Noninvasive exploration of cardiac autonomic neuropathy. Four reliable methods for diabetes? (7/2230)
OBJECTIVE: The purpose of this work was to assess relevant information that could be provided by various mathematical analyses of spontaneous blood pressure (BP) and heart rate (HR) variabilities in diabetic cardiovascular neuropathy. RESEARCH DESIGN AND METHODS: There were 10 healthy volunteers and 11 diabetic subjects included in the study. Diabetic patients were selected for nonsymptomatic orthostatic hypotension in an assessment of their cardiovascular autonomic impairment. Cardiac autonomic function was scored according to Ewing's methodology adapted to the use of a Finapres device. The spontaneous beat-to-beat BP and HR variabilities were then analyzed on a 1-h recording in supine subjects. The global variabilities were assessed by standard deviation, fractal dimension, and spectral power. The cardiac baroreflex function was estimated by cross-spectral sequences and Z analyses. RESULTS: In diabetic patients, Ewing's scores ranged from 1 to 4.5, confirming cardiovascular autonomic dysfunction. In these diabetic patients, global indices of variabilities were consistently lower than in healthy subjects. Furthermore, some of them (standard deviation and fractal dimension of HR, spectral power of systolic blood pressure and HR) were significantly correlated with the Ewing's scores. The Z methods and the spectral analysis found that the cardiac baroreflex was less effective in diabetic subjects. However, the baroreflex sensitivity could not be reliably assessed in all the patients. The sequence method pointed out a decreased number of baroreflex sequences in diabetic subjects that was correlated to the Ewing's score. CONCLUSIONS: Indices of HR spontaneous beat-to-beat variability are consistently related to the degree of cardiac autonomic dysfunction, according to Ewing's methodology. The Z method and spectral analysis confirmed that the cardiac baroreflex was impaired in diabetic patients. These methods might be clinically relevant for use in detecting incipient neuropathy in diabetic patients. (+info)Detection of autonomic sympathetic dysfunction in diabetic patients. A study using laser Doppler imaging. (8/2230)
OBJECTIVE: To study signs of the disturbed reflex autonomic sympathetic nerve function in type 1 and type 2 diabetic patients. RESEARCH DESIGN AND METHODS: Measurements were made on 15 type 1 (duration 13-32 years) and on 50 recently diagnosed type 2 diabetic patients (duration 3-4 years). The vasoconstrictor responses in the distal phalanx of the middle finger (locally heated to 40 degrees C) to the cooling of the contralateral arm were measured using Laser Doppler Imaging (LDI). A vasoconstriction index (VAC) was calculated taking age into account and was compared with reference values obtained in 80 control subjects. The diabetic patients were also studied with deep-breathing tests (i.e., the heart-rate variation expressed as the expiration-to-inspiration [E/I] ratio, a test of parasympathetic nerve function). RESULTS: The vasoconstrictor responses to indirect cooling (VAC) were significantly reduced in the fingers of the diabetic patients, both type 2 (0.77 +/- 0.02 V; P < 0.01) and type 1 (0.83 +/- 0.04 V; P < 0.001), compared with the healthy control subjects (0.65 +/- 0.01); the age-corrected VAC (VACz) was slightly more impaired in type 1 than in type 2 diabetic patients. The frequency of an abnormal VACz corresponded well to the frequency of an abnormal E/I ratio in type 1 diabetic patients (approximately 50%), whereas the frequency of an abnormal VACz was significantly higher than an abnormal E/I ratio among type 2 diabetic patients (11/50 vs. 4/50; P < 0.05). CONCLUSIONS: Both type 1 and type 2 diabetic patients have impaired cutaneous blood flow regulation. The VAC index seems to be a promising tool for detection of subclinical changes in autonomic sympathetic function. (+info)There are many different types of ANS diseases, including:
1. Dysautonomia: a general term that refers to dysfunction of the autonomic nervous system.
2. Postural orthostatic tachycardia syndrome (POTS): a condition characterized by rapid heart rate and other symptoms that occur upon standing.
3. Neurocardiogenic syncope: a form of fainting caused by a sudden drop in blood pressure.
4. Multiple system atrophy (MSA): a progressive neurodegenerative disorder that affects the autonomic nervous system and other parts of the brain.
5. Parkinson's disease: a neurodegenerative disorder that can cause autonomic dysfunction, including constipation, urinary incontinence, and erectile dysfunction.
6. Dopamine deficiency: a condition characterized by low levels of the neurotransmitter dopamine, which can affect the ANS and other body systems.
7. Autonomic nervous system disorders associated with autoimmune diseases, such as Guillain-Barré syndrome and lupus.
8. Trauma: physical or emotional trauma can sometimes cause dysfunction of the autonomic nervous system.
9. Infections: certain infections, such as Lyme disease, can affect the autonomic nervous system.
10. Genetic mutations: some genetic mutations can affect the functioning of the autonomic nervous system.
Treatment for ANS diseases depends on the specific condition and its underlying cause. In some cases, medication may be prescribed to regulate heart rate, blood pressure, or other bodily functions. Lifestyle changes, such as regular exercise and stress management techniques, can also be helpful in managing symptoms. In severe cases, surgery may be necessary to correct anatomical abnormalities or repair damaged nerves.
When the sinus node is not functioning properly, it can lead to an arrhythmia, or irregular heartbeat. This can cause a variety of symptoms, including palpitations, shortness of breath, fatigue, and dizziness. In some cases, sinus arrhythmia can be caused by underlying medical conditions such as coronary artery disease, high blood pressure, or cardiomyopathy.
There are several types of sinus arrhythmia, including:
* Sinus tachycardia: a rapid heart rate due to an overactive sinus node. This can be caused by stress, anxiety, or physical exertion.
* Sinus bradycardia: a slow heart rate due to a decreased activity in the sinus node. This can be caused by certain medications, age, or underlying medical conditions.
* Sinus arrest: a complete cessation of sinus node activity, leading to a stop in the heartbeat. This is a rare condition and can be caused by a variety of factors, including electrolyte imbalances or certain medications.
Treatment for sinus arrhythmia depends on the underlying cause and the severity of symptoms. In some cases, no treatment may be necessary, while in other cases, medication or procedures such as cardioversion or catheter ablation may be required. It is important to seek medical attention if symptoms persist or worsen over time, as untreated sinus arrhythmia can lead to more serious complications such as stroke or heart failure.
1. Neurodegenerative diseases: These are diseases that cause progressive loss of brain cells, leading to cognitive decline and motor dysfunction. Examples include Alzheimer's disease, Parkinson's disease, and Huntington's disease.
2. Stroke: A stroke occurs when blood flow to the brain is interrupted, leading to cell death and potential long-term disability.
3. Traumatic brain injury: This type of injury occurs when the brain is subjected to a sudden and forceful impact, such as in a car accident or fall.
4. Infections: Bacterial, viral, and fungal infections can all cause CNS diseases, such as meningitis and encephalitis.
5. Autoimmune disorders: These are conditions in which the immune system mistakenly attacks healthy cells in the brain, leading to inflammation and damage. Examples include multiple sclerosis and lupus.
6. Brain tumors: Tumors can occur in any part of the brain and can be benign or malignant.
7. Cerebrovascular diseases: These are conditions that affect the blood vessels in the brain, such as aneurysms and arteriovenous malformations (AVMs).
8. Neurodevelopmental disorders: These are conditions that affect the development of the brain and nervous system, such as autism spectrum disorder and attention deficit hyperactivity disorder (ADHD).
CNS diseases can have a significant impact on quality of life, and some can be fatal. Treatment options vary depending on the specific diagnosis and severity of the disease. Some CNS diseases can be managed with medication, while others may require surgery or other interventions.
Some of the symptoms of familial dysautonomia are similar to those found in other types of dysautonomia, such as difficulty regulating body temperature, blood pressure changes, and gastrointestinal disturbances. However, people with familial dysautonomia may also experience additional signs and symptoms that are unique to the condition.
Research has identified several genetic mutations or variations that can cause familial dysautonomia. These include:
1. Mutations in the EDNRB gene, which codes for the dopamine receptor beta subunit. This gene is important for regulating the activity of the autonomic nervous system.
2. Variations in the THAP11 gene, which codes for a protein that plays a role in the development and function of the autonomic nervous system.
3. Mutations in the KCNQ2 and KCNQ3 genes, which code for potassium channels that are important for regulating the activity of the autonomic nervous system.
Familial dysautonomia is a rare condition, and it can be difficult to diagnose because its symptoms can be similar to those of other conditions. However, a diagnosis may be made based on a combination of clinical findings, genetic testing, and the exclusion of other potential causes of the symptoms.
There is no cure for familial dysautonomia, but treatment options are available to help manage the symptoms. These may include medications to regulate blood pressure or heart rate, therapies to improve gastrointestinal function, and measures to prevent complications such as dehydration or heat stroke. In addition, individuals with familial dysautonomia may need to make lifestyle adjustments to accommodate their condition, such as avoiding extreme temperatures or taking regular breaks to rest.
Familial dysautonomia is a rare and complex condition that can have a significant impact on quality of life. However, with proper management and support, individuals with this condition can lead fulfilling lives.
Benign CNS neoplasms include:
1. Meningiomas: These are the most common type of benign CNS tumor, arising from the meninges (the membranes covering the brain and spinal cord).
2. Acoustic neuromas: These tumors arise from the nerve cells that connect the inner ear to the brain.
3. Pineal gland tumors: These are rare tumors that occur in the pineal gland, a small gland located in the brain.
4. Craniopharyngiomas: These are rare tumors that arise from the remnants of the embryonic pituitary gland and can cause a variety of symptoms including headaches, vision loss, and hormonal imbalances.
Malignant CNS neoplasms include:
1. Gliomas: These are the most common type of malignant CNS tumor and arise from the supporting cells of the brain called glial cells. Examples of gliomas include astrocytomas, oligodendrogliomas, and medulloblastomas.
2. Lymphomas: These are cancers of the immune system that can occur in the CNS.
3. Melanomas: These are rare tumors that arise from the pigment-producing cells of the skin and can spread to other parts of the body, including the CNS.
4. Metastatic tumors: These are tumors that have spread to the CNS from other parts of the body, such as the breast, lung, or colon.
The diagnosis and treatment of central nervous system neoplasms depend on the type, size, location, and severity of the tumor, as well as the patient's overall health and medical history. Treatment options can include surgery, radiation therapy, chemotherapy, targeted therapy, and immunotherapy.
The prognosis for CNS neoplasms varies depending on the type of tumor and the effectiveness of treatment. In general, gliomas have a poorer prognosis than other types of CNS tumors, with five-year survival rates ranging from 30% to 60%. Lymphomas and melanomas have better prognoses, with five-year survival rates of up to 80%. Metastatic tumors have a more guarded prognosis, with five-year survival rates depending on the primary site of the cancer.
In summary, central nervous system neoplasms are abnormal growths of tissue in the brain and spinal cord that can cause a variety of symptoms and can be benign or malignant. The diagnosis and treatment of these tumors depend on the type, size, location, and severity of the tumor, as well as the patient's overall health and medical history. The prognosis for CNS neoplasms varies depending on the type of tumor and the effectiveness of treatment, but in general, gliomas have a poorer prognosis than other types of CNS tumors.
There are many different types of cardiac arrhythmias, including:
1. Tachycardias: These are fast heart rhythms that can be too fast for the body's needs. Examples include atrial fibrillation and ventricular tachycardia.
2. Bradycardias: These are slow heart rhythms that can cause symptoms like fatigue, dizziness, and fainting. Examples include sinus bradycardia and heart block.
3. Premature beats: These are extra beats that occur before the next regular beat should come in. They can be benign but can also indicate an underlying arrhythmia.
4. Supraventricular arrhythmias: These are arrhythmias that originate above the ventricles, such as atrial fibrillation and paroxysmal atrial tachycardia.
5. Ventricular arrhythmias: These are arrhythmias that originate in the ventricles, such as ventricular tachycardia and ventricular fibrillation.
Cardiac arrhythmias can be diagnosed through a variety of tests including electrocardiograms (ECGs), stress tests, and holter monitors. Treatment options for cardiac arrhythmias vary depending on the type and severity of the condition and may include medications, cardioversion, catheter ablation, or implantable devices like pacemakers or defibrillators.
There are several possible causes of hypoventilation, including:
1. Respiratory muscle weakness or paralysis: This can be due to a variety of conditions, such as muscular dystrophy, amyotrophic lateral sclerosis (ALS), or spinal cord injury.
2. Chronic respiratory failure: This can be caused by conditions such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, or pulmonary fibrosis.
3. Sleep apnea: Hypoventilation can occur during sleep due to the loss of muscle tone in the diaphragm and other respiratory muscles.
4. Anesthesia-induced hypoventilation: Some anesthetics can suppress the respiratory drive, leading to hypoventilation.
5. Drug overdose or intoxication: Certain drugs, such as opioids and benzodiazepines, can depress the central nervous system and lead to hypoventilation.
6. Trauma: Hypoventilation can occur in patients with severe injuries to the chest or abdomen that impair breathing.
7. Sepsis: Severe infections can cause hypoventilation by suppressing the respiratory drive.
8. Metabolic disorders: Certain metabolic disorders, such as diabetic ketoacidosis, can lead to hypoventilation.
Treatment of hypoventilation depends on the underlying cause and may include oxygen therapy, mechanical ventilation, and addressing any underlying conditions or complications. In some cases, hypoventilation may be a sign of a more severe condition that requires prompt medical attention to prevent further complications and improve outcomes.
The symptoms of Shy-Drager Syndrome can vary widely among individuals and may include:
* Cognitive decline
* Memory loss
* Difficulty with speech and language
* Loss of coordination and balance
* Dysphagia (difficulty swallowing)
* Weakness or paralysis of the limbs
* Bladder and bowel dysfunction
* Sleep disturbances
The exact cause of Shy-Drager Syndrome is not yet fully understood, but it is believed to be related to an autoimmune response, in which the body's immune system mistakenly attacks healthy cells in the brain. Genetic factors may also play a role in the development of the disorder.
There is no cure for Shy-Drager Syndrome, but various medications and therapies can help manage its symptoms. These may include:
* Cholinesterase inhibitors to improve cognitive function and slow the progression of dementia
* Anticholinergic drugs to reduce muscle rigidity and tremors
* Physical therapy to maintain mobility and strength
* Speech and language therapy to improve communication skills
* Occupational therapy to support daily living activities
The prognosis for Shy-Drager Syndrome is generally poor, with a median survival time of around 10-15 years after onset of symptoms. However, the rate of progression can vary widely among individuals, and some may experience a more gradual decline over several decades.
Overall, Shy-Drager Syndrome is a rare and complex disorder that requires careful management by a multidisciplinary team of healthcare professionals. While there is no cure for the condition, various therapies can help manage its symptoms and improve the quality of life for affected individuals.
* Heart block: A condition where the electrical signals that control the heart's rhythm are blocked or delayed, leading to a slow heart rate.
* Sinus node dysfunction: A condition where the sinus node, which is responsible for setting the heart's rhythm, is not functioning properly, leading to a slow heart rate.
* Medications: Certain medications, such as beta blockers, can slow down the heart rate.
* Heart failure: In severe cases of heart failure, the heart may become so weak that it cannot pump blood effectively, leading to a slow heart rate.
* Electrolyte imbalance: An imbalance of electrolytes, such as potassium or magnesium, can affect the heart's ability to function properly and cause a slow heart rate.
* Other medical conditions: Certain medical conditions, such as hypothyroidism (an underactive thyroid) or anemia, can cause bradycardia.
Bradycardia can cause symptoms such as:
* Fatigue
* Weakness
* Dizziness or lightheadedness
* Shortness of breath
* Chest pain or discomfort
In some cases, bradycardia may not cause any noticeable symptoms at all.
If you suspect you have bradycardia, it is important to consult with a healthcare professional for proper diagnosis and treatment. They may perform tests such as an electrocardiogram (ECG) or stress test to determine the cause of your slow heart rate and develop an appropriate treatment plan. Treatment options for bradycardia may include:
* Medications: Such as atropine or digoxin, to increase the heart rate.
* Pacemakers: A small device that is implanted in the chest to help regulate the heart's rhythm and increase the heart rate.
* Cardiac resynchronization therapy (CRT): A procedure that involves implanting a device that helps both ventricles of the heart beat together, improving the heart's pumping function.
It is important to note that bradycardia can be a symptom of an underlying condition, so it is important to address the underlying cause in order to effectively treat the bradycardia.
The most common types of CNS infections include:
1. Meningitis: Inflammation of the protective membranes (meninges) that cover the brain and spinal cord, often caused by bacteria or viruses.
2. Encephalitis: Inflammation of the brain tissue itself, usually caused by a virus.
3. Abscesses: Pockets of pus that form in the brain or spinal cord, typically caused by bacterial infections.
4. Cryptococcal infections: Caused by a fungus called Cryptococcus neoformans, often affecting people with weakened immune systems.
5. Toxoplasmosis: A parasitic infection caused by the Toxoplasma gondii parasite, which can affect the CNS in people with compromised immune systems.
Symptoms of CNS infections can vary depending on the specific type and severity of the infection, but may include fever, headache, confusion, seizures, weakness, and stiff neck. Diagnosis is typically made through a combination of physical examination, laboratory tests, and imaging studies such as CT or MRI scans.
Treatment of CNS infections depends on the underlying cause, but may involve antibiotics, antiviral medications, or antifungal drugs. In severe cases, hospitalization and supportive care such as intravenous fluids, oxygen therapy, and respiratory support may be necessary.
Prevention of CNS infections includes good hygiene practices such as frequent handwashing, avoiding close contact with people who are sick, and getting vaccinated against certain viruses that can cause CNS infections. Early diagnosis and prompt treatment are critical to preventing long-term complications of CNS infections and improving outcomes for patients.
Examples of Nervous System Diseases include:
1. Alzheimer's disease: A progressive neurological disorder that affects memory and cognitive function.
2. Parkinson's disease: A degenerative disorder that affects movement, balance and coordination.
3. Multiple sclerosis: An autoimmune disease that affects the protective covering of nerve fibers.
4. Stroke: A condition where blood flow to the brain is interrupted, leading to brain cell death.
5. Brain tumors: Abnormal growth of tissue in the brain.
6. Neuropathy: Damage to peripheral nerves that can cause pain, numbness and weakness in hands and feet.
7. Epilepsy: A disorder characterized by recurrent seizures.
8. Motor neuron disease: Diseases that affect the nerve cells responsible for controlling voluntary muscle movement.
9. Chronic pain syndrome: Persistent pain that lasts more than 3 months.
10. Neurodevelopmental disorders: Conditions such as autism, ADHD and learning disabilities that affect the development of the brain and nervous system.
These diseases can be caused by a variety of factors such as genetics, infections, injuries, toxins and ageing. Treatment options for Nervous System Diseases range from medications, surgery, rehabilitation therapy to lifestyle changes.
Some common types of nervous system neoplasms include:
1. Brain tumors: These are abnormal growths that develop in the brain, including gliomas (such as glioblastoma), meningiomas, and acoustic neuromas.
2. Spinal cord tumors: These are abnormal growths that develop in the spinal cord, including astrocytomas, oligodendrogliomas, and metastatic tumors.
3. Nerve sheath tumors: These are abnormal growths that develop in the covering of nerves, such as neurofibromas and schwannomas.
4. Pineal gland tumors: These are abnormal growths that develop in the pineal gland, a small endocrine gland located in the brain.
Symptoms of nervous system neoplasms can vary depending on their location and size, but may include headaches, seizures, weakness or numbness in the arms or legs, and changes in vision, speech, or balance. Diagnosis is typically made through a combination of imaging studies (such as MRI or CT scans) and tissue biopsy. Treatment options vary depending on the type and location of the tumor, but may include surgery, radiation therapy, and chemotherapy.
In summary, nervous system neoplasms are abnormal growths that can develop in the brain, spinal cord, and nerves, and can have a significant impact on the body. Diagnosis and treatment require a comprehensive approach, involving a team of medical professionals with expertise in neurology, neurosurgery, radiation oncology, and other related specialties.
There are several possible causes of orthostatic hypotension, including:
1. Deconditioning: This is a common cause of orthostatic hypotension in older adults who have been bedridden or hospitalized for prolonged periods.
2. Medication side effects: Certain medications, such as beta blockers and vasodilators, can cause orthostatic hypotension as a side effect.
3. Heart conditions: Conditions such as heart failure, arrhythmias, and structural heart defects can lead to orthostatic hypotension.
4. Neurological disorders: Certain neurological disorders, such as Parkinson's disease, multiple sclerosis, and stroke, can cause orthostatic hypotension.
5. Vasomotor instability: This is a condition where the blood vessels constrict or dilate rapidly, leading to a drop in blood pressure.
6. Anemia: A low red blood cell count can lead to a decrease in oxygen delivery to the body's tissues, causing orthostatic hypotension.
7. Dehydration: Dehydration can cause a drop in blood volume and lead to orthostatic hypotension.
8. Hypovolemia: This is a condition where there is a low volume of blood in the body, leading to a drop in blood pressure.
9. Sepsis: Sepsis can cause vasodilation and lead to orthostatic hypotension.
10. Other causes: Other causes of orthostatic hypotension include adrenal insufficiency, thyroid disorders, and certain genetic conditions.
Symptoms of orthostatic hypotension may include:
* Dizziness or lightheadedness
* Fainting
* Blurred vision
* Nausea and vomiting
* Headaches
* Fatigue
* Weakness
* Confusion
If you experience any of these symptoms, it is important to seek medical attention as soon as possible. Your healthcare provider can perform a physical examination and order diagnostic tests to determine the underlying cause of your orthostatic hypotension. Treatment will depend on the specific cause, but may include medications to raise blood pressure, fluid replacement, and addressing any underlying conditions.
Examples of abnormal reflexes include:
1. Overactive reflexes: Reflexes that are too strong or exaggerated, such as an oversensitive knee jerk reflex.
2. Underactive reflexes: Reflexes that are too weak or diminished, such as a decreased tendon reflex in the arm.
3. Delayed reflexes: Reflexes that take longer than expected to occur, such as a delayed deep tendon reflex.
4. Abnormal reflex arc: A reflex arc that is not normal or expected for the situation, such as a spastic reflex arc.
5. Reflexes that are out of proportion to the stimulus: Such as an excessive or exaggerated reflex response to a mild stimulus.
6. Reflexes that occur in the absence of a stimulus: Such as a spontaneous reflex.
7. Reflexes that do not resolve: Such as a persistent reflex.
8. Reflexes that are painful or uncomfortable: Such as an abnormal rectal reflex.
It's important to note that not all abnormal reflexes are necessarily indicative of a serious medical condition, but they should be evaluated by a healthcare professional to determine the underlying cause and appropriate treatment.
1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.
2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.
3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.
4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.
5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.
6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.
7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.
8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.
9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.
10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.
There are two types of hypertension:
1. Primary Hypertension: This type of hypertension has no identifiable cause and is also known as essential hypertension. It accounts for about 90% of all cases of hypertension.
2. Secondary Hypertension: This type of hypertension is caused by an underlying medical condition or medication. It accounts for about 10% of all cases of hypertension.
Some common causes of secondary hypertension include:
* Kidney disease
* Adrenal gland disorders
* Hormonal imbalances
* Certain medications
* Sleep apnea
* Cocaine use
There are also several risk factors for hypertension, including:
* Age (the risk increases with age)
* Family history of hypertension
* Obesity
* Lack of exercise
* High sodium intake
* Low potassium intake
* Stress
Hypertension is often asymptomatic, and it can cause damage to the blood vessels and organs over time. Some potential complications of hypertension include:
* Heart disease (e.g., heart attacks, heart failure)
* Stroke
* Kidney disease (e.g., chronic kidney disease, end-stage renal disease)
* Vision loss (e.g., retinopathy)
* Peripheral artery disease
Hypertension is typically diagnosed through blood pressure readings taken over a period of time. Treatment for hypertension may include lifestyle changes (e.g., diet, exercise, stress management), medications, or a combination of both. The goal of treatment is to reduce the risk of complications and improve quality of life.
Some common examples of CNSVD include:
1. Herpes simplex virus (HSV) encephalitis: This is an inflammation of the brain caused by the herpes simplex virus. It can cause fever, headache, confusion, and seizures.
2. West Nile virus (WNV) encephalitis: This is an infection of the brain caused by the West Nile virus, which is transmitted through the bite of an infected mosquito. Symptoms can include fever, headache, muscle weakness, and confusion.
3. Japanese encephalitis (JE): This is a viral infection that affects the brain and is transmitted through the bite of an infected mosquito. Symptoms can include fever, headache, seizures, and changes in behavior or cognitive function.
4. Rabies: This is a viral infection that affects the brain and is transmitted through the bite of an infected animal, usually a dog, bat, or raccoon. Symptoms can include fever, headache, agitation, and changes in behavior or cognitive function.
5. Enteroviral encephalitis: This is an infection of the brain caused by enteroviruses, which are common viruses that affect the gastrointestinal tract. Symptoms can include fever, vomiting, diarrhea, and changes in behavior or cognitive function.
The diagnosis of CNSVD typically involves a combination of physical examination, laboratory tests (such as blood tests or lumbar puncture), and imaging studies (such as CT or MRI scans). Treatment options vary depending on the specific disease and may include antiviral medications, supportive care, and rehabilitation.
Prevention of CNSVD includes avoiding exposure to mosquitoes and other vectors that can transmit disease, maintaining good hygiene practices (such as washing hands frequently), and getting vaccinated against diseases such as rabies and measles. In addition, taking steps to prevent head trauma and using protective equipment when engaging in activities that involve risk of head injury can help reduce the risk of CNSVD.
Overall, while central nervous system viral diseases can be serious and potentially life-threatening, early diagnosis and treatment can improve outcomes and prevent long-term complications. It is important to seek medical attention promptly if symptoms persist or worsen over time.
Paragangliomas are rare, accounting for less than 1% of all tumors diagnosed in adults. They can occur at any age but are more common in young adults and middle-aged individuals. These tumors are more common in males than females, and their incidence is higher in certain families with inherited syndromes, such as neurofibromatosis type 1 (NF1) or familial paraganglioma.
The symptoms of paraganglioma depend on their location and size. Small tumors may not cause any symptoms, while larger tumors can press on nearby organs and structures, causing a variety of symptoms such as:
* Pain in the abdomen or pelvis
* Swelling or lump in the neck or abdomen
* High blood pressure
* Headaches
* Blurred vision
* Confusion or seizures (in cases of malignant paraganglioma)
Paragangliomas are difficult to diagnose, as they can be mistaken for other conditions such as appendicitis or pancreatitis. Imaging studies such as CT or MRI scans are often used to help identify the location and size of the tumor, while laboratory tests may be used to evaluate hormone levels and other factors that can help differentiate paraganglioma from other conditions.
Treatment for paraganglioma depends on the type, size, and location of the tumor, as well as the patient's overall health status. Small, benign tumors may not require treatment, while larger or malignant tumors may be treated with surgery, chemotherapy, or radiation therapy. In some cases, a combination of these treatments may be used.
The prognosis for paraganglioma is generally good if the tumor is diagnosed and treated early, but it can be poor if the tumor is large or has spread to other parts of the body. With surgical removal of the tumor, the 5-year survival rate is approximately 90% for patients with benign paraganglioma and 30-50% for those with malignant paraganglioma. However, the overall prognosis can vary depending on individual factors such as the size and location of the tumor, the effectiveness of treatment, and the patient's underlying health status.
There are several types of diabetic neuropathies, including:
1. Peripheral neuropathy: This is the most common type of diabetic neuropathy and affects the nerves in the hands and feet. It can cause numbness, tingling, and pain in these areas.
2. Autonomic neuropathy: This type of neuropathy affects the nerves that control involuntary functions, such as digestion, bladder function, and blood pressure. It can cause a range of symptoms, including constipation, diarrhea, urinary incontinence, and sexual dysfunction.
3. Proximal neuropathy: This type of neuropathy affects the nerves in the legs and hips. It can cause weakness, pain, and stiffness in these areas.
4. Focal neuropathy: This type of neuropathy affects a single nerve, often causing sudden and severe pain.
The exact cause of diabetic neuropathies is not fully understood, but it is thought to be related to high blood sugar levels over time. Other risk factors include poor blood sugar control, obesity, smoking, and alcohol consumption. There is no cure for diabetic neuropathy, but there are several treatments available to manage the symptoms and prevent further nerve damage. These treatments may include medications, physical therapy, and lifestyle changes such as regular exercise and a healthy diet.
In extreme cases, hypoglycemia can lead to seizures, loss of consciousness, and even coma. It is important to recognize the symptoms of hypoglycemia early on and seek medical attention if they persist or worsen over time. Treatment typically involves raising blood sugar levels through the consumption of quick-acting carbohydrates such as glucose tablets, fruit juice, or hard candy.
If left untreated, hypoglycemia can have serious consequences, including long-term damage to the brain, heart, and other organs. It is important for individuals with diabetes to monitor their blood sugar levels regularly and work with their healthcare provider to manage their condition effectively.
www.medicinenet.com/sudden_death/article.htm
Sudden death is death that occurs unexpectedly and without warning, often due to a cardiac arrest or other underlying medical condition.
In the medical field, sudden death is defined as death that occurs within one hour of the onset of symptoms, with no prior knowledge of any serious medical condition. It is often caused by a cardiac arrhythmia, such as ventricular fibrillation or tachycardia, which can lead to cardiac arrest and sudden death if not treated promptly.
Other possible causes of sudden death include:
1. Heart disease: Coronary artery disease, heart failure, and other heart conditions can increase the risk of sudden death.
2. Stroke: A stroke can cause sudden death by disrupting blood flow to the brain or other vital organs.
3. Pulmonary embolism: A blood clot in the lungs can block blood flow and cause sudden death.
4. Trauma: Sudden death can occur as a result of injuries sustained in an accident or other traumatic event.
5. Drug overdose: Taking too much of certain medications or drugs can cause sudden death due to cardiac arrest or respiratory failure.
6. Infections: Sepsis, meningitis, and other severe infections can lead to sudden death if left untreated.
7. Genetic conditions: Certain inherited disorders, such as Long QT syndrome, can increase the risk of sudden death due to cardiac arrhythmias.
The diagnosis of sudden death often requires an autopsy and a thorough investigation into the individual's medical history and circumstances surrounding their death. Treatment and prevention strategies may include defibrillation, CPR, medications to regulate heart rhythm, and lifestyle modifications to reduce risk factors such as obesity, smoking, and high blood pressure.
The exact cause of CNS vasculitis is not fully understood, but it is believed to be an autoimmune disorder, meaning that the immune system mistakenly attacks healthy tissues in the CNS. The condition can occur at any age, but it most commonly affects adults between the ages of 40 and 60.
Symptoms of CNS vasculitis can vary depending on the location and severity of the inflammation, but may include:
* Headaches
* Confusion
* Memory loss
* Seizures
* Weakness or numbness in the limbs
* Vision problems
* Speech difficulties
Diagnosis of CNS vasculitis typically involves a combination of physical examination, medical history, and diagnostic tests such as MRI or CT scans, lumbar puncture, and blood tests. Treatment options for CNS vasculitis vary depending on the severity of the condition and may include corticosteroids, immunosuppressive drugs, and plasmapheresis. In severe cases, surgery may be necessary to relieve pressure on the brain or spinal cord.
Overall, CNS vasculitis is a serious condition that can have significant neurological consequences if left untreated. Early diagnosis and aggressive treatment are critical to prevent long-term damage and improve outcomes for patients with this condition.
Examples of syndromes include:
1. Down syndrome: A genetic disorder caused by an extra copy of chromosome 21 that affects intellectual and physical development.
2. Turner syndrome: A genetic disorder caused by a missing or partially deleted X chromosome that affects physical growth and development in females.
3. Marfan syndrome: A genetic disorder affecting the body's connective tissue, causing tall stature, long limbs, and cardiovascular problems.
4. Alzheimer's disease: A neurodegenerative disorder characterized by memory loss, confusion, and changes in personality and behavior.
5. Parkinson's disease: A neurological disorder characterized by tremors, rigidity, and difficulty with movement.
6. Klinefelter syndrome: A genetic disorder caused by an extra X chromosome in males, leading to infertility and other physical characteristics.
7. Williams syndrome: A rare genetic disorder caused by a deletion of genetic material on chromosome 7, characterized by cardiovascular problems, developmental delays, and a distinctive facial appearance.
8. Fragile X syndrome: The most common form of inherited intellectual disability, caused by an expansion of a specific gene on the X chromosome.
9. Prader-Willi syndrome: A genetic disorder caused by a defect in the hypothalamus, leading to problems with appetite regulation and obesity.
10. Sjogren's syndrome: An autoimmune disorder that affects the glands that produce tears and saliva, causing dry eyes and mouth.
Syndromes can be diagnosed through a combination of physical examination, medical history, laboratory tests, and imaging studies. Treatment for a syndrome depends on the underlying cause and the specific symptoms and signs presented by the patient.
There are several types of tachycardia, including:
1. Sinus tachycardia: This is the most common type and is caused by an increase in the rate of the normal sinus node. It is often seen in response to physical activity or stress.
2. Atrial fibrillation: This is a type of arrhythmia where the heart's upper chambers (atria) contract irregularly and rapidly, leading to a rapid heart rate.
3. Ventricular tachycardia: This is a type of arrhythmia where the heart's lower chambers (ventricles) contract rapidly, often with a rate above 100 bpm.
4. Premature ventricular contractions (PVCs): These are early or extra beats that originate in the ventricles, causing a rapid heart rate.
Tachycardia can cause a range of symptoms, including palpitations, shortness of breath, chest pain, and dizziness. In severe cases, it can lead to cardiac arrhythmias, heart failure, and even death.
Diagnosis of tachycardia typically involves a physical examination, electrocardiogram (ECG), and other tests such as stress tests or echocardiography. Treatment options vary depending on the underlying cause, but may include medications to regulate the heart rate, cardioversion to restore a normal heart rhythm, or in severe cases, implantation of a pacemaker or defibrillator.
Some examples of the use of 'Death, Sudden, Cardiac' in medical contexts include:
1. Sudden cardiac death (SCD) is a major public health concern, affecting thousands of people each year in the United States alone. It is often caused by inherited heart conditions, such as hypertrophic cardiomyopathy or long QT syndrome.
2. The risk of sudden cardiac death is higher for individuals with a family history of heart disease or other pre-existing cardiovascular conditions.
3. Sudden cardiac death can be prevented by prompt recognition and treatment of underlying heart conditions, as well as by avoiding certain risk factors such as smoking, physical inactivity, and an unhealthy diet.
4. Cardiopulmonary resuscitation (CPR) and automated external defibrillators (AEDs) can be effective in restoring a normal heart rhythm during sudden cardiac death, especially when used promptly after the onset of symptoms.
There are several causes of hypotension, including:
1. Dehydration: Loss of fluids and electrolytes can cause a drop in blood pressure.
2. Blood loss: Losing too much blood can lead to hypotension.
3. Medications: Certain medications, such as diuretics and beta-blockers, can lower blood pressure.
4. Heart conditions: Heart failure, cardiac tamponade, and arrhythmias can all cause hypotension.
5. Endocrine disorders: Hypothyroidism (underactive thyroid) and adrenal insufficiency can cause low blood pressure.
6. Vasodilation: A condition where the blood vessels are dilated, leading to low blood pressure.
7. Sepsis: Severe infection can cause hypotension.
Symptoms of hypotension can include:
1. Dizziness and lightheadedness
2. Fainting or passing out
3. Weakness and fatigue
4. Confusion and disorientation
5. Pale, cool, or clammy skin
6. Fast or weak pulse
7. Shortness of breath
8. Nausea and vomiting
If you suspect that you or someone else is experiencing hypotension, it is important to seek medical attention immediately. Treatment will depend on the underlying cause of the condition, but may include fluids, electrolytes, and medication to raise blood pressure. In severe cases, hospitalization may be necessary.
The exact cause of vasovagal syncope is not fully understood, but it is thought to be related to an imbalance in the autonomic nervous system (which controls involuntary functions such as heart rate and blood pressure). It can be triggered by a variety of factors, including:
* Strong emotions such as fear or anxiety
* Pain or discomfort
* Intense physical activity
* Dehydration or low blood sugar
* Certain medications
During a vasovagal syncope episode, the person may experience symptoms such as:
* Dizziness or lightheadedness
* Blurred vision
* Nausea or vomiting
* Sweating
* Feeling of impending doom or loss of control
* Eventually, fainting or falling to the ground
Diagnosis of vasovagal syncope is typically made based on a combination of symptoms and physical examination findings. Tests such as an electrocardiogram (ECG) or blood tests may be ordered to rule out other conditions that may be causing the symptoms. Treatment for vasovagal syncope usually involves addressing any underlying triggers, such as managing stress or avoiding certain stimuli that may cause the episodes. In some cases, medications such as beta blockers or antidepressants may be prescribed to help regulate the heart rate and blood pressure.
There are several risk factors for developing AF, including:
1. Age: The risk of developing AF increases with age, with the majority of cases occurring in people over the age of 65.
2. Hypertension (high blood pressure): High blood pressure can damage the heart and increase the risk of developing AF.
3. Heart disease: People with heart disease, such as coronary artery disease or heart failure, are at higher risk of developing AF.
4. Diabetes mellitus: Diabetes can increase the risk of developing AF.
5. Sleep apnea: Sleep apnea can increase the risk of developing AF.
6. Certain medications: Certain medications, such as thyroid medications and asthma medications, can increase the risk of developing AF.
7. Alcohol consumption: Excessive alcohol consumption has been linked to an increased risk of developing AF.
8. Smoking: Smoking is a risk factor for many cardiovascular conditions, including AF.
9. Obesity: Obesity is a risk factor for many cardiovascular conditions, including AF.
Symptoms of AF can include:
1. Palpitations (rapid or irregular heartbeat)
2. Shortness of breath
3. Fatigue
4. Dizziness or lightheadedness
5. Chest pain or discomfort
AF can be diagnosed with the help of several tests, including:
1. Electrocardiogram (ECG): This is a non-invasive test that measures the electrical activity of the heart.
2. Holter monitor: This is a portable device that records the heart's rhythm over a 24-hour period.
3. Event monitor: This is a portable device that records the heart's rhythm over a longer period of time, usually 1-2 weeks.
4. Echocardiogram: This is an imaging test that uses sound waves to create pictures of the heart.
5. Cardiac MRI: This is an imaging test that uses magnetic fields and radio waves to create detailed pictures of the heart.
Treatment for AF depends on the underlying cause and may include medications, such as:
1. Beta blockers: These medications slow the heart rate and reduce the force of the heart's contractions.
2. Antiarrhythmics: These medications help regulate the heart's rhythm.
3. Blood thinners: These medications prevent blood clots from forming and can help reduce the risk of stroke.
4. Calcium channel blockers: These medications slow the entry of calcium into the heart muscle cells, which can help slow the heart rate and reduce the force of the heart's contractions.
In some cases, catheter ablation may be recommended to destroy the abnormal electrical pathway causing AF. This is a minimally invasive procedure that involves inserting a catheter through a vein in the leg and guiding it to the heart using x-ray imaging. Once the catheter is in place, energy is applied to the abnormal electrical pathway to destroy it and restore a normal heart rhythm.
It's important to note that AF can increase the risk of stroke, so anticoagulation therapy may be recommended to reduce this risk. This can include medications such as warfarin or aspirin, or in some cases, implantable devices such as a left atrial appendage closure device.
In conclusion, atrial fibrillation is a common heart rhythm disorder that can increase the risk of stroke and heart failure. Treatment options depend on the underlying cause and may include medications, cardioversion, catheter ablation, or anticoagulation therapy. It's important to work closely with a healthcare provider to determine the best course of treatment for AF.
There are several subtypes of IBS, including:
* IBS-C (constipation-predominant)
* IBS-D (diarrhea-predominant)
* IBS-M (mixed)
The symptoms of IBS can vary in severity and frequency from person to person, and may include:
* Abdominal pain or cramping
* Bloating
* Gas
* Diarrhea or constipation
* Mucus in the stool
* Feeling of incomplete evacuation after bowel movements
There is no cure for IBS, but symptoms can be managed with dietary changes, stress management techniques, and medications such as fiber supplements, antispasmodics, and antidepressants. It is important to seek medical advice if symptoms persist or worsen over time, as IBS can have a significant impact on quality of life and may be associated with other conditions such as anxiety or depression.
Trauma to the nervous system can have a profound impact on an individual's quality of life, and can lead to a range of symptoms including:
* Headaches
* Dizziness and vertigo
* Memory loss and difficulty concentrating
* Mood changes such as anxiety, depression, or irritability
* Sleep disturbances
* Changes in sensation, such as numbness or tingling
* Weakness or paralysis of certain muscle groups
Trauma to the nervous system can also have long-lasting effects, and may lead to chronic conditions such as post-traumatic stress disorder (PTSD), chronic pain, and fibromyalgia.
Treatment for trauma to the nervous system will depend on the specific nature of the injury and the severity of the symptoms. Some common treatments include:
* Medication to manage symptoms such as pain, anxiety, or depression
* Physical therapy to help regain strength and mobility
* Occupational therapy to help with daily activities and improve function
* Cognitive-behavioral therapy (CBT) to address any emotional or psychological issues
* Alternative therapies such as acupuncture, massage, or meditation to help manage symptoms and promote relaxation.
It's important to seek medical attention if you experience any symptoms of trauma to the nervous system, as prompt treatment can help reduce the risk of long-term complications and improve outcomes.
The most common types of CNS fungal infections include:
1. Meningitis: An inflammation of the membranes that cover the brain and spinal cord, caused by fungi such as Candida, Aspergillus, or Cryptococcus.
2. Encephalitis: An inflammation of the brain tissue itself, caused by fungi such as Histoplasma or Coccidioides.
3. Abscesses: Pocket of pus that form in the brain or spinal cord, caused by bacteria or fungi.
4. Opportunistic infections: Infections that occur in people with compromised immune systems, such as HIV/AIDS patients or those taking immunosuppressive drugs after an organ transplant.
CNS fungal infections can cause a wide range of symptoms, including headache, fever, confusion, seizures, and loss of coordination. They are typically diagnosed through a combination of physical examination, laboratory tests, and imaging studies such as CT or MRI scans.
Treatment of CNS fungal infections usually involves the use of antifungal medications, which can be administered intravenously or orally. The choice of treatment depends on the severity and location of the infection, as well as the patient's overall health status. In some cases, surgery may be necessary to drain abscesses or relieve pressure on the brain.
Prevention of CNS fungal infections is important for individuals at risk, such as those with compromised immune systems or underlying medical conditions. This includes taking antifungal medications prophylactically, avoiding exposure to fungal spores, and practicing good hygiene.
Overall, CNS fungal infections are serious and potentially life-threatening conditions that require prompt diagnosis and treatment. With appropriate management, many patients can recover fully, but delays in diagnosis and treatment can lead to poor outcomes.
Myocardial ischemia can be caused by a variety of factors, including coronary artery disease, high blood pressure, diabetes, and smoking. It can also be triggered by physical exertion or stress.
There are several types of myocardial ischemia, including:
1. Stable angina: This is the most common type of myocardial ischemia, and it is characterized by a predictable pattern of chest pain that occurs during physical activity or emotional stress.
2. Unstable angina: This is a more severe type of myocardial ischemia that can occur without any identifiable trigger, and can be accompanied by other symptoms such as shortness of breath or vomiting.
3. Acute coronary syndrome (ACS): This is a condition that includes both stable angina and unstable angina, and it is characterized by a sudden reduction in blood flow to the heart muscle.
4. Heart attack (myocardial infarction): This is a type of myocardial ischemia that occurs when the blood flow to the heart muscle is completely blocked, resulting in damage or death of the cardiac tissue.
Myocardial ischemia can be diagnosed through a variety of tests, including electrocardiograms (ECGs), stress tests, and imaging studies such as echocardiography or cardiac magnetic resonance imaging (MRI). Treatment options for myocardial ischemia include medications such as nitrates, beta blockers, and calcium channel blockers, as well as lifestyle changes such as quitting smoking, losing weight, and exercising regularly. In severe cases, surgical procedures such as coronary artery bypass grafting or angioplasty may be necessary.
There are several different types of pain, including:
1. Acute pain: This type of pain is sudden and severe, and it usually lasts for a short period of time. It can be caused by injuries, surgery, or other forms of tissue damage.
2. Chronic pain: This type of pain persists over a long period of time, often lasting more than 3 months. It can be caused by conditions such as arthritis, fibromyalgia, or nerve damage.
3. Neuropathic pain: This type of pain results from damage to the nervous system, and it can be characterized by burning, shooting, or stabbing sensations.
4. Visceral pain: This type of pain originates in the internal organs, and it can be difficult to localize.
5. Psychogenic pain: This type of pain is caused by psychological factors such as stress, anxiety, or depression.
The medical field uses a range of methods to assess and manage pain, including:
1. Pain rating scales: These are numerical scales that patients use to rate the intensity of their pain.
2. Pain diaries: These are records that patients keep to track their pain over time.
3. Clinical interviews: Healthcare providers use these to gather information about the patient's pain experience and other relevant symptoms.
4. Physical examination: This can help healthcare providers identify any underlying causes of pain, such as injuries or inflammation.
5. Imaging studies: These can be used to visualize the body and identify any structural abnormalities that may be contributing to the patient's pain.
6. Medications: There are a wide range of medications available to treat pain, including analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), and muscle relaxants.
7. Alternative therapies: These can include acupuncture, massage, and physical therapy.
8. Interventional procedures: These are minimally invasive procedures that can be used to treat pain, such as nerve blocks and spinal cord stimulation.
It is important for healthcare providers to approach pain management with a multi-modal approach, using a combination of these methods to address the physical, emotional, and social aspects of pain. By doing so, they can help improve the patient's quality of life and reduce their suffering.
CNS bacterial infections can cause a wide range of symptoms, including fever, headache, confusion, seizures, and loss of consciousness. In severe cases, these infections can lead to meningitis, encephalitis, or abscesses in the brain or spinal cord.
The diagnosis of CNS bacterial infections is based on a combination of clinical findings, laboratory tests, and imaging studies. Laboratory tests may include blood cultures, cerebrospinal fluid (CSF) cultures, and polymerase chain reaction (PCR) tests to identify the causative bacteria. Imaging studies, such as computed tomography (CT) or magnetic resonance imaging (MRI), may be used to visualize the extent of the infection.
Treatment of CNS bacterial infections typically involves the use of antibiotics, which can help to clear the infection and prevent further complications. In some cases, surgical intervention may be necessary to drain abscesses or relieve pressure on the brain or spinal cord.
Preventive measures for CNS bacterial infections include vaccination against certain types of bacteria, such as Streptococcus pneumoniae and Haemophilus influenzae, good hygiene practices, and appropriate use of antibiotics. Early diagnosis and treatment are critical to preventing long-term neurological damage or death.
In conclusion, CNS bacterial infections can be serious and potentially life-threatening conditions that require prompt diagnosis and treatment. Understanding the causes, symptoms, diagnosis, treatment, and prevention of these infections is essential for effective management and optimal outcomes for patients affected by them.
There are several key features of inflammation:
1. Increased blood flow: Blood vessels in the affected area dilate, allowing more blood to flow into the tissue and bringing with it immune cells, nutrients, and other signaling molecules.
2. Leukocyte migration: White blood cells, such as neutrophils and monocytes, migrate towards the site of inflammation in response to chemical signals.
3. Release of mediators: Inflammatory mediators, such as cytokines and chemokines, are released by immune cells and other cells in the affected tissue. These molecules help to coordinate the immune response and attract more immune cells to the site of inflammation.
4. Activation of immune cells: Immune cells, such as macrophages and T cells, become activated and start to phagocytose (engulf) pathogens or damaged tissue.
5. Increased heat production: Inflammation can cause an increase in metabolic activity in the affected tissue, leading to increased heat production.
6. Redness and swelling: Increased blood flow and leakiness of blood vessels can cause redness and swelling in the affected area.
7. Pain: Inflammation can cause pain through the activation of nociceptors (pain-sensing neurons) and the release of pro-inflammatory mediators.
Inflammation can be acute or chronic. Acute inflammation is a short-term response to injury or infection, which helps to resolve the issue quickly. Chronic inflammation is a long-term response that can cause ongoing damage and diseases such as arthritis, asthma, and cancer.
There are several types of inflammation, including:
1. Acute inflammation: A short-term response to injury or infection.
2. Chronic inflammation: A long-term response that can cause ongoing damage and diseases.
3. Autoimmune inflammation: An inappropriate immune response against the body's own tissues.
4. Allergic inflammation: An immune response to a harmless substance, such as pollen or dust mites.
5. Parasitic inflammation: An immune response to parasites, such as worms or fungi.
6. Bacterial inflammation: An immune response to bacteria.
7. Viral inflammation: An immune response to viruses.
8. Fungal inflammation: An immune response to fungi.
There are several ways to reduce inflammation, including:
1. Medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying anti-rheumatic drugs (DMARDs).
2. Lifestyle changes, such as a healthy diet, regular exercise, stress management, and getting enough sleep.
3. Alternative therapies, such as acupuncture, herbal supplements, and mind-body practices.
4. Addressing underlying conditions, such as hormonal imbalances, gut health issues, and chronic infections.
5. Using anti-inflammatory compounds found in certain foods, such as omega-3 fatty acids, turmeric, and ginger.
It's important to note that chronic inflammation can lead to a range of health problems, including:
1. Arthritis
2. Diabetes
3. Heart disease
4. Cancer
5. Alzheimer's disease
6. Parkinson's disease
7. Autoimmune disorders, such as lupus and rheumatoid arthritis.
Therefore, it's important to manage inflammation effectively to prevent these complications and improve overall health and well-being.
Autonomic nervous system
ROHHAD
Harlequin syndrome
Pure autonomic failure
Fight-or-flight response
John Newport Langley
Norepinephrine
Julio Licinio
Endoscopic thoracic sympathectomy
Postprandial somnolence
Thoracic splanchnic nerves
Peripheral Arterial Tone
Joshua Harold Burn
Sudomotor
Head and neck anatomy
Splanchnic nerves
Nicotine
Acetylcholinesterase
Heart rate variability
Neuron doctrine
PPP1R1B
Acetylcholinesterase inhibitor
Flourishing
Sympathetic ganglia
Transcendental Meditation technique
Thapsigargin
Digitalis
Phosphodiesterase inhibitor
NISCH
Neural top-down control of physiology
Multiple system atrophy
Janina Hurynowicz
Striated muscle tissue
Sympathoadrenal system
Dementia with Lewy bodies
Marcello Costa
Negativity bias
Chronic cerebrospinal venous insufficiency controversy
American Autonomic Society
Peripheral neuropathy
American Meditation Institute
Wilder Penfield
James A. Pawelczyk
Bovine spongiform encephalopathy
Brain-body interaction
Human penis
Platostoma menthoides
Norepinephrine transporter
Spinal cord injury
Overflow incontinence
Neuroscience of aging
Pain
Babinski-Nageotte syndrome
Internal spermatic fascia
Zung Self-Rating Anxiety Scale
David Sheffield Bell
Accelerans nerve
Primary autonomic failure
Electrochemical skin conductance
Cardiac pacemaker
Dysautonomia | Autonomic Nervous System Disorders | MedlinePlus
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Yoga and the Autonomic Nervous System
Parasympathetic25
- The neurotransmitter for preganglionic sympathetic and parasympathetic nervous system (PNS) as well as postganglionic parasympathetic nervous system is acetylcholine (ACh). (medscape.com)
- Although new techniques in neuroscience and molecular genetics are being used to elucidate the neuroanatomy and function of the ANS, much remains unknown regarding the contribution of the parasympathetic and sympathetic nervous systems in the regulation of glucose and lipid homeostasis. (nih.gov)
- Overall, the role of the parasympathetic and sympathetic nervous systems in the etiology and pathophysiology of metabolic diseases remains a scientific area ripe for development. (nih.gov)
- Its main components are its sensory system, motor system (comprised of the parasympathetic nervous system and sympathetic nervous system ), and the enteric nervous system . (wikidoc.org)
- The preganglionic cell bodies of the parasympathetic system are located in the brain stem and sacral portion of the spinal cord. (msdmanuals.com)
- Understand the antagonism between the sympathetic and parasympathetic divisions of the autonomic nervous systems. (mhmedical.com)
- See how the sympathetic and parasympathetic divisions of the autonomic nervous system operate at the spinal cord level. (mhmedical.com)
- The autonomic nervous system consists of sympathetic and parasympathetic branches that generally have opposite effects on organs such as the heart and lungs. (mhmedical.com)
- The sympathetic system activates the fight-or-flight response, whereas parasympathetic activity promotes homeostatic functions such as digestion and the immune system. (mhmedical.com)
- It is a positive feedback loop and without conditioning your parasympathetic system to take over, your body begins to be in a constant state of stress. (masteringhealthandfitness.com)
- Our lives throw so much stress our way, that our brains never activate the "relax" or parasympathetic nervous system. (masteringhealthandfitness.com)
- Yoga Trains our bodies to use the sympathetic system when needed, and retrains our parasympathetic system to take over when we aren't actually in fight or flight. (masteringhealthandfitness.com)
- Yoga creates a battle field between your sympathetic nervous system and parasympathetic system. (masteringhealthandfitness.com)
- Breathing activates the parasympathetic system so you start and end activating your "relax" system. (masteringhealthandfitness.com)
- Stretching also activates the parasympathetic system. (masteringhealthandfitness.com)
- After making it through a Bikram yoga class where your Autonomic Nervous System Battles between Sympathetic and Parasympathetic for 90 min we begin to condition ourselves to handle sympathetic responses better and shut them off quickly by activating our parasympathetic system. (masteringhealthandfitness.com)
- It is composed of sympathetic and parasympathetic systems which work in opposition to each other. (abcbooksllc.com)
- This classic chart ofThe Autonomic Nervous System shows the pathways of both the parasympathetic and the sympathetic systems. (abcbooksllc.com)
- Sweating is the one exception that acts just like the parasympathetic nervous system in its organization of the neurotransmitters and target receptors. (byui.edu)
- One thing that you'll come to realize is that the high frequency of the spectral power of heart rate variability is associated with the parasympathetic system, whereas the low frequency is associated with both the parasympathetic and the sympathetic nervous system. (labfront.com)
- So the parasympathetic nervous system involves the acetylcholine coming from the post ganglion of the power to set the sympathetic nervous system binding to the amp to the muscarinic receptor, activating the G protein, which then subsequently activates this potassium-associated acetylcholine channel. (labfront.com)
- So if there was no intervention from either the sympathetic or the vagal system or the parasympathetic system, you would have this type of automaticity of the electrical potential. (labfront.com)
- Together, these parameters can aid the physician to obtain detailed insights in the dynamics of sympathetic and parasympathetic innervation of the human cardiovascular system. (medtach.com)
- Physiologists have discovered two divisions of the autonomic nervous system, i.e., sympathetic division and parasympathetic division. (sweducarebd.com)
- The parasympathetic system is responsible for regulating sleep and digestion. (doxyva.com)
Dysfunction9
- Investigating the possible mechanisms of autonomic dysfunction post-COVID-19. (nih.gov)
- Autonomic Dysfunction Related to Postacute SARS-CoV-2 Syndrome. (nih.gov)
- The etiology of autonomic dysfunction can be primary or idiopathic and secondary causes. (medscape.com)
- In addition, autonomic dysfunction is associated with various medications. (medscape.com)
- Clinical research in this area is severely hampered by a paucity of tools and/or methodologies available to assess tissue-specific autonomic function or dysfunction. (nih.gov)
- Autonomic nervous system dysfunction in mild traumatic brain injury: a review of related pathophysiology and symptoms. (iasp-pain.org)
- NAS usually appears within 48-72 hours of birth with a constellation of clinical signs, including central nervous system irritability (e.g., tremors), gastrointestinal dysfunction (e.g., feeding difficulties), and temperature instability ( 1 ) ( Box 1 ). (cdc.gov)
- Understand the organs controlled by the autonomic nervous system and notable disorders associated with autonomic nervous system dysfunction. (mhmedical.com)
- People may also experience disturbances of the autonomic nervous system that manifest as problems with digestion, respiration, salivation as well as excessive sweating, bladder dysfunction, or sexual dysfunction. (nih.gov)
Neurotransmitters6
- See how the neurotransmitters acetylcholine (ACh) and norepinephrine mediate autonomic nervous system control. (mhmedical.com)
- Another drug mechanism that can affect the autonomic nervous system involves inhibition of enzymes that break down the normally secreted neurotransmitters. (byui.edu)
- The autonomic nervous system works alongside your body's neurotransmitters and hormones in order to ensure that your body is working correctly. (doxyva.com)
- In order to communicate with one another, the two branches of the autonomic nervous system use special chemical hormones, called neurotransmitters. (doxyva.com)
- If something goes wrong with these neurotransmitters, messages from the body to the autonomic nervous system can easily be confused. (doxyva.com)
- Along with neurotransmitters, your autonomic nervous system also relies on hormones in order to stimulate certain bodily functions. (doxyva.com)
Physiology1
- To serve as a case-based, interactive auto-tutorial on the anatomy, physiology, and pharmacology of the autonomic nervous system (ANS). (bvsalud.org)
Disorders6
- Autonomic nervous system disorders can occur alone or as the result of another disease, such as Parkinson's disease , alcoholism and diabetes. (medlineplus.gov)
- Some autonomic nervous system disorders get better when an underlying disease is treated. (medlineplus.gov)
- Given the complex nature of this system, a stepwise approach to autonomic disorders is required for proper understanding. (medscape.com)
- Because the autonomic nervous system maintains internal physiologic homeostasis, disorders of this system can be present with both central as well as peripheral nervous system localization. (medscape.com)
- In addition to the acquired causes, inherited disorders like hereditary sensory-autonomic neuropathy (HSAN), familial amyloid polyneuropathy (FAP), Tangier disease, and Fabry disease also exist. (medscape.com)
- Disorders of the autonomic nervous system cause autonomic insufficiency or failure and can affect any system of the body. (msdmanuals.com)
Acetylcholine2
- The neurotransmitter for the postganglionic sympathetic nervous system (innervating sweat glands) is also acetylcholine, whereas that for the remaining postganglionic sympathetic nervous system is norepinephrine (NE). (medscape.com)
- But, that is because general sweating is the one exception in the sympathetic nervous system that has acetylcholine in the second synapse between neuron and target organ. (byui.edu)
Peripheral8
- Updates on the Diagnosis and Treatment of Peripheral Autonomic Neuropathies. (nih.gov)
- Besides nerve localization in the peripheral nervous system, it occurs in diseases of the presynaptic neuromuscular junction such as botulism and myasthenic syndrome. (medscape.com)
- Afferent fibers relay sensory and metabolic information to the central nervous system, while efferent fibers provide the major neural pathway from the brain to peripheral tissues. (nih.gov)
- The autonomic nervous system ( ANS ) (or visceral nervous system ) is the part of the peripheral nervous system that acts as a control system, maintaining homeostasis in the body. (wikidoc.org)
- The sensory arm is made of " primary visceral sensory neurons" found in the peripheral nervous system (PNS), in "cranial sensory ganglia": the geniculate , petrosal and nodose ganglia, appended respectively to cranial nerves VII, IX and X. These sensory neurons monitor the levels of carbon dioxide, oxygen and sugar in the blood, arterial pressure and the chemical composition of the stomach and gut content. (wikidoc.org)
- This Funding Opportunity Announcement (FOA) will be published under a new FOA Number, PAR-18-898 , Elucidating the Role of the Autonomic Nervous System in Peripheral Metabolism and Metabolic Disease through the Application of Novel Tools and Methodologies (RC2 Clinical Trial Optional). (nih.gov)
- The visceral system of the Peripheral Nervous System is known as the Autonomic Nervous System. (sweducarebd.com)
- The sensory (afferent) and motor (efferent) nerves connecting the body's surface with the central nervous system constitute the peripheral nervous system. (sweducarebd.com)
Multiple System1
- Autonomic failure is seen in multiple system atrophy, pure or progressive autonomic failure, Parkinson and other neurodegenerative diseases, metabolic diseases such as Wernicke and cobalamin deficiency, diabetes mellitus, hyperlipidemia, trauma, vascular diseases, neoplastic diseases, and multiple sclerosis . (medscape.com)
Norepinephrine3
- Acetylcholinesterase inhibitors do affect the sympathetic nervous system in the first synapse but not the second synapse where norepinephrine is released. (byui.edu)
- The sympathetic nervous system, on the other hand, operates through norepinephrine or epinephrine that binds to the beta one receptors. (labfront.com)
- Norepinephrine is a hormone released by your adrenal gland and controlled by your sympathetic nervous system. (doxyva.com)
Cardiac2
- The autonomic nervous system receives inputs from receptors in glands and cardiac and smooth muscle and sends motor commands to those areas. (mhmedical.com)
- Together the two systems control cardiac muscles, smooth muscles, and glands. (abcbooksllc.com)
Responses3
- Autonomic and Vascular Responses during Reactive Hyperemia in Healthy Individuals and Patients with Sickle Cell Anemia. (nih.gov)
- Imagery contents influence autonomic responses, thus making it comparable to real activity. (nih.gov)
- The autonomic nervous system (ANS) plays a critical role in the regulation of physiological responses required for maintaining metabolic homeostasis. (nih.gov)
Enteric nervou1
- The enteric nervous system is the nervous system of digestion. (mhmedical.com)
Sweat glands1
- The autonomic actions energising sweat glands lead to perspiration, which produces changes in the electrical properties of the skin. (sweducarebd.com)
Physiologic2
- The autonomic nervous system (ANS) is a very complex, multifaceted neural network that maintains internal physiologic homeostasis. (medscape.com)
- The autonomic nervous system regulates physiologic processes. (msdmanuals.com)
Arousal1
- The researchers measured changes in skin conductance (how fast the skin conducts electricity), a known indicator of autonomic arousal. (nih.gov)
Fibers2
- Small myelinated fibers transmit preganglionic autonomic efferents (B fibers) and somatic afferents (A delta fibers). (medscape.com)
- Unmyelinated (C) fibers transmit postganglionic autonomic efferents as well as somatic and autonomic afferents. (medscape.com)
Regulation1
- Short- and long-term effects of massage on autonomic regulation differed significantly among the three groups. (jcimjournal.com)
Ganglia1
- Vertebrate ganglia are the control centers for the autonomic and enteric nervous systems. (mhmedical.com)
Receptors2
- Having an understanding of the ANS and its particular receptors located on effectors and the drugs that activate or block these receptors will assist your understanding of the actions of this system. (byui.edu)
- The eye has multiple autonomic functions controlled by several autonomic receptors. (byui.edu)
Regulates1
- The ANS is the part of the nervous system that regulates processes in the body that we do not consciously control, such as our breathing, heartbeat, and digestion. (nih.gov)
Pharmacology1
- Autonomic and autacoid pharmacology. (who.int)
Tissues2
- In this workshop, we will use movement, touch, consciousness, and dialogue to explore basic processes stored in our tissues and autonomic nervous system. (bodymindcentering.com)
- For some reason, the autonomic nervous system doesn't trigger the release of enough growth hormone to help repair muscles and tissues. (doxyva.com)
Nerves1
- Autonomic nerves are attractive targets for medical therapies using electroceutical devices because of the potential for selective control and few side effects. (nih.gov)
Search1
- Results of search for 'su:{Autonomic nervous system. (who.int)
Anatomy1
- The goal for this article remains focused at step III on the anatomy of the autonomic nervous system, as follows. (medscape.com)
Involuntary2
- Your autonomic nervous system is the part of your nervous system that controls involuntary actions, such as the beating of your heart and the widening or narrowing of your blood vessels. (medlineplus.gov)
- The Autonomic Nervous System is the involuntary functioning part of the nervous system that controls the internal organs of the body. (abcbooksllc.com)
System's3
- How a person perceives and evaluates stimuli involving actual or prospective pain is an important component in the autonomic nervous system's (ANS) response to such stimuli, according to a study conducted by researchers in the Intramural Program of the National Center for Complementary and Integrative Health (NCCIH). (nih.gov)
- The ANS is part of the response to pain, which also includes "nociception"-the nervous system's encoding and processing of a "noxious" (an actually or potentially harmful) stimulus, such as a hot stove or freezing water. (nih.gov)
- your nervous system's conductor. (trptwellness.com)
Processes2
- The autonomic nervous system (ANS) plays a vital role in maintaining and regulating homeostatic processes. (iasp-pain.org)
- The brain also interacts with an extended nervous system outside the brain that controls body metabolic processes such as respiration, heart rate, temperature, and digestion. (mhmedical.com)
Preganglionic2
- The activity of autonomic ganglionic neurons is modulated by "preganglionic neurons" (also called improperly but classically "visceral motoneurons") located in the central nervous system. (wikidoc.org)
- The preganglionic cell bodies of the sympathetic system are located in the intermediolateral horn of the spinal cord between T1 and L2 or L3. (msdmanuals.com)
Receives1
- The autonomic nervous system receives input from parts of the central nervous system (CNS) that process and integrate stimuli from the body and external environment. (msdmanuals.com)
Body's1
- The autonomic nervous system is an important part of your body's central nervous system (CNS). (doxyva.com)
Organization1
- Understand the organization and projections of the cephalic portion of the autonomic nervous system. (mhmedical.com)
Central5
- This explains that when the central nervous system (CNS) is damaged experimentally or by accident above that level, a vegetative life is still possible, whereby cardiovascular, digestive and respiratory functions are adequately regulated. (wikidoc.org)
- Fluphenazine hydrochloride has activity at all levels of the central nervous system as well as on multiple organ systems. (nih.gov)
- These systems interact with the central nervous system (CNS) in the brainstem and hypothalamus. (mhmedical.com)
- The synapse of the system is situated outside of both the spinal column and central nervous system. (sweducarebd.com)
- PD's effects on the central nervous system are both chronic (meaning they persist) and progressive (meaning the symptoms grow worse over time). (nih.gov)
Branches1
- There are two parts to your autonomic nervous system, which are referred to as branches. (doxyva.com)
Intervention1
- Les patients ont été répartis aléatoirement en deux groupes, le premier bénéficiant d'une intervention basée sur le yoga contrairement au second. (who.int)
Spinal cord1
- Marca Sipski is serving as president of the American Spinal Cord Injury Association (ASIA) and is active in the development of standards for autonomic nervous system function in spinal cord injury (SCI). (nih.gov)
Cardiovascular system1
- The authors aimed to investigate the physiological action of RMT on the cardiovascular system by analysing heart rate variability (HRV). (jcimjournal.com)
Body2
- The nervous system is responsible for communicating vital messages to various parts of your body, helping you to act and react, see, touch, taste, and feel. (doxyva.com)
- It helps to control a variety of different organs in your body as well as numerous bodily systems. (doxyva.com)
Heart4
- On one hand, you are exercising: increasing your heart rate, blood pressure, and breathing rate activating your sympathetic system. (masteringhealthandfitness.com)
- The Autonomic Testing (AT) software application enables the Baroreceptor Sensitivity (BRS) and various Heart Rate Variability (HRV) parameters on a Finapres ® NOVA Plus with an ECG module. (medtach.com)
- Heart rate and cardiovascular function are regulated by the autonomic nervous system. (cdc.gov)
- Heart rate variability (HRV) as a marker reflects the activity of autonomic nervous system. (cdc.gov)
Stimulate1
- We still face situations that stimulate our Sympathetic Nervous System (the fight or flight system), they just aren't in animal form. (masteringhealthandfitness.com)
Fight-or-fli1
- Once upon a time, our autonomic nervous systems sent us into fight-or-flight mode when we perceived danger - often before our conscious minds were even aware of a predator. (wellbodymindheartspirit.com)
Functions1
- New findings related to autonomic nervous system (ANS) functions may reveal some brain functions, since they can be observed by real time analysis. (nih.gov)