Autonomic Denervation: The removal or interruption of some part of the autonomic nervous system for therapeutic or research purposes.Autonomic Nervous System Diseases: Diseases of the parasympathetic or sympathetic divisions of the AUTONOMIC NERVOUS SYSTEM; which has components located in the CENTRAL NERVOUS SYSTEM and PERIPHERAL NERVOUS SYSTEM. Autonomic dysfunction may be associated with HYPOTHALAMIC DISEASES; BRAIN STEM disorders; SPINAL CORD DISEASES; and PERIPHERAL NERVOUS SYSTEM DISEASES. Manifestations include impairments of vegetative functions including the maintenance of BLOOD PRESSURE; HEART RATE; pupil function; SWEATING; REPRODUCTIVE AND URINARY PHYSIOLOGY; and DIGESTION.Denervation: The resection or removal of the nerve to an organ or part. (Dorland, 28th ed)Muscle Denervation: The resection or removal of the innervation of a muscle or muscle tissue.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)Water-Electrolyte Imbalance: Disturbances in the body's WATER-ELECTROLYTE BALANCE.Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Cardio-Renal Syndrome: Condition where a primary dysfunction of either heart or kidney results in failure of the other organ (e.g., HEART FAILURE with worsening RENAL INSUFFICIENCY).Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Stellate Ganglion: A paravertebral sympathetic ganglion formed by the fusion of the inferior cervical and first thoracic ganglia.Anti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Rest: Freedom from activity.Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Apathy: Lack of emotion or emotional expression; a disorder of motivation that persists over time.Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.Sympathectomy: The removal or interruption of some part of the sympathetic nervous system for therapeutic or research purposes.Blood Pressure Monitoring, Ambulatory: Method in which repeated blood pressure readings are made while the patient undergoes normal daily activities. It allows quantitative analysis of the high blood pressure load over time, can help distinguish between types of HYPERTENSION, and can assess the effectiveness of antihypertensive therapy.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Electric Stimulation: Use of electric potential or currents to elicit biological responses.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Blood Pressure Determination: Techniques for measuring blood pressure.Antihypertensive Agents: Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.Receptors, Neuropeptide Y: Cell surface proteins that bind neuropeptide Y with high affinity and trigger intracellular changes which influence the behavior of cells.Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Dexamethasone: An anti-inflammatory 9-fluoro-glucocorticoid.Neuropeptide Y: A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has vasoconstrictor and natriuretic activity and regulates local blood flow, glandular secretion, and smooth muscle activity. The peptide also stimulates feeding and drinking behavior and influences secretion of pituitary hormones.Glucose Clamp Technique: Maintenance of a constant blood glucose level by perfusion or infusion with glucose or insulin. It is used for the study of metabolic rates (e.g., in glucose, lipid, amino acid metabolism) at constant glucose concentration.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.JapanAwards and PrizesSocieties, Medical: Societies whose membership is limited to physicians.Chemistry, Analytic: The branch of chemistry dealing with detection (qualitative) and determination (quantitative) of substances. (Grant & Hackh's Chemical Dictionary, 5th ed)United StatesTh2 Cells: Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.Food Hypersensitivity: Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food.Gastroenterology: A subspecialty of internal medicine concerned with the study of the physiology and diseases of the digestive system and related structures (esophagus, liver, gallbladder, and pancreas).Yogurt: A slightly acid milk food produced by fermentation due to the combined action of Lactobacillus acidophilus and Streptococcus thermophilus.Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.Wine: Fermented juice of fresh grapes or of other fruit or plant products used as a beverage.Onions: Herbaceous biennial plants and their edible bulbs, belonging to the Liliaceae.

Sino-aortic denervation augments the increase in blood pressure seen during paradoxical sleep in the rat. (1/71)

Using a computer assisted telemetric system, we have re-examined the effect of sino-aortic denervation (SAD) on the changes in arterial blood pressure (AP) and heart rate (HR) during sleep in the rat suitably recovered from the operation. Eight 1 hourly polygraphic recordings were performed 4 weeks after the initial SAD surgery. In the SAD rats, the increase in AP during paradoxical sleep (PS) was much larger than that in sham-operated rats. HR in the SAD rats increased on-going from slow-wave sleep to PS, but it showed no change in sham-operated rats. The present study suggests that chronic SAD causes the enhanced AP increase during PS concomitantly with the persistent hypertension and tachycardia across sleep-wake states.  (+info)

Autonomic control of skeletal muscle blood flow at the onset of exercise. (2/71)

The purpose of this study was to determine whether the autonomic nervous system is involved in skeletal muscle vasodilation at the onset of exercise. Mongrel dogs (n = 7) were instrumented with flow probes on both external iliac arteries. Before treadmill exercise at 3 miles/h, 0% grade, hexamethonium (10 mg/kg) and atropine (0.2 mg/kg) or saline was infused intravenously. Ganglionic blockade increased resting heart rate from 87 +/- 5 to 145 +/- 8 beats/min (P < 0.01) and reduced mean arterial pressure from 100 +/- 4 to 88 +/- 5 mmHg (P < 0.01). During steady-state exercise, heart rate was unaffected by ganglionic blockade (from 145 +/- 8 to 152 +/- 5 beats/min), whereas mean arterial pressure was reduced (from 115 +/- 4 to 72 +/- 4 mmHg; P < 0.01). Immediate and rapid increases in iliac blood flow and conductance occurred with initiation of exercise with or without ganglionic blockade. Statistical analyses of hindlimb conductance at 5-s intervals over the first 30 s of exercise revealed a statistically significant difference between the control and ganglionic blockade conditions at 20, 25, and 30 s (P < 0.01) but not at 5, 10, and 15 s of exercise. Hindlimb conductance at 1 min of exercise was 9.21 +/- 0.68 and 11.82 +/- 1.32 ml. min(-1). mmHg(-1) for the control and ganglionic blockade conditions, respectively. Because ganglionic blockade did not affect the initial rise in iliac conductance, we concluded that the autonomic nervous system is not essential for the rapid vasodilation in active skeletal muscle at the onset of exercise in dogs. Autonomic control of skeletal muscle blood flow during exercise is manifested through vasoconstriction and not vasodilation.  (+info)

The influence of acute hypoxia and carotid body denervation on thermoregulation during non-rapid eye movement sleep in the developing lamb. (3/71)

We investigated the influence of ambient temperature on the thermoregulatory response to hypoxia in developing lambs before (at 4 and 14 days of age) and after (17 and 30 days of age) carotid body denervation (CBD). Lambs were studied during non-rapid eye movement sleep at thermoneutral (23-15 C) and cool (10-5 C) ambient temperatures, during normoxia and acute hypoxia (inspired oxygen content of 13 %). Measurements of oxygen consumption, arterial partial pressures of O2 and CO2, colonic temperature, incidence of shivering and plasma concentrations of thyroid hormones, cortisol, insulin and glucose were made under each condition. Oxygen consumption was higher at cool compared with thermoneutral ambient temperatures and decreased during hypoxia during cooling at all stages. At 4 days of age, only one lamb shivered during cooling in normoxia, but 4 out of 12 lambs shivered during hypoxia and colonic temperature fell, significantly, by 0.2 C. At 14 days, 8 out of 12 lambs shivered during cooling, of which 6 continued to shiver during hypoxia but colonic temperature did not change significantly. Plasma triiodothyronine concentrations increased on cooling at 4 and 14 days, an affect that was inhibited by hypoxia at 4, but not 14 days of age. At 17 days of age, i.e. post-CBD, plasma thyroid hormone concentrations and oxygen consumption were lower during cold exposure compared with intact lambs at 14 days of age. In CBD lambs, imposing further hypoxia resulted in colonic temperature falling 0. 6 C during cooling, with only 2 out of 10 lambs shivering. Plasma glucose and insulin, but not cortisol, concentrations decreased during hypoxia, irrespective of age or CBD. It is concluded that hypoxia has an important influence on metabolism and thermoregulation, which is modulated by age and environmental conditions. Compromised carotid body function, in lambs older than 2 weeks of age, can result in severe hypoxia and thermoregulatory dysfunction even with modest environmental cooling.  (+info)

Ileal short-chain fatty acids inhibit gastric motility by a humoral pathway. (4/71)

The aim of this study was to evaluate the nervous and humoral pathways involved in short-chain fatty acid (SCFA)-induced ileal brake in conscious pigs. The role of extrinsic ileal innervation was evaluated after SCFA infusion in innervated and denervated Babkin's ileal loops, and gastric motility was measured with strain gauges. Peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) concentrations were evaluated in both situations. The possible involvement of absorbed SCFA was tested by using intravenous infusion of acetate. Ileal SCFA infusion in the intact terminal ileum decreased the amplitude of distal and terminal antral contractions (33 +/- 1.2 vs. 49 +/- 1.2% of the maximal amplitude recorded before infusion) and increased their frequency (1.5 +/- 0.11 vs. 1.3 +/- 0.10/min). Similar effects were observed during SCFA infusion in ileal innervated and denervated loops (amplitude, 35 +/- 1.0 and 34 +/- 0. 8 vs. 47 +/- 1.3 and 43 +/- 1.2%; frequency, 1.4 +/- 0.07 and 1.6 +/- 0.06 vs. 1.1 +/- 0.14 and 1.0 +/- 0.12/min). Intravenous acetate did not modify the amplitude and frequency of antral contractions. PYY but not GLP-1 concentrations were increased during SCFA infusion in innervated and denervated loops. In conclusion, ileal SCFA inhibit distal gastric motility by a humoral pathway involving the release of an inhibiting factor, which is likely PYY.  (+info)

c-Fos expression in the midbrain periaqueductal gray during static muscle contraction. (5/71)

The periaqueductal gray (PAG) of the midbrain is involved in the autonomic regulation of the cardiovascular system. The purpose of this study was to determine if static contraction of the skeletal muscle, which increases arterial blood pressure and heart rate, activates neuronal cells in the PAG by examining Fos-like immunoreactivity (FLI). Muscle contraction was induced by electrical stimulation of the L7 and S1 ventral roots of the spinal cord in anesthetized cats. An intravenous infusion of phenylephrine (PE) was used to selectively activate arterial baroreceptors. Extensive FLI was observed within the ventromedial region (VM) of the rostral PAG, the dorsolateral (DL), lateral (L), and ventrolateral (VL) regions of the middle and caudal PAG in barointact animals with muscle contractions, and in barointact animals with PE infusion. However, muscle contraction caused a lesser number of FLI in the VM region of the rostral PAG, the DL, L, and VL regions of the middle PAG and the L and VL regions of the caudal PAG after barodenervation compared with barointact animals. Additionally, the number of FLI in the DL and L regions of the middle PAG was greater in barodenervated animals with muscle contraction than in barodenervated control animals. Thus these results indicated that both muscle receptor and baroreceptor afferent inputs activate neuronal cells in regions of the PAG during muscle contraction. Furthermore, afferents from skeletal muscle activate neurons in specific regions of the PAG independent of arterial baroreceptor input. Therefore, neuronal cells in the PAG may play a role in determining the cardiovascular responses during the exercise pressor reflex.  (+info)

Hepatic parasympathetic (HISS) control of insulin sensitivity determined by feeding and fasting. (6/71)

In response to insulin, a hormone [hepatic insulin sensitizing substance (HISS)] is released from the liver to stimulate glucose uptake in skeletal muscle but not liver or gut. The aim was to characterize dynamic control of HISS action in response to insulin and regulation of release by hepatic parasympathetic nerves. Insulin action was assessed by the rapid insulin sensitivity test, where the index is the glucose required (mg/kg) to maintain euglycemia after a bolus of insulin. Blocking HISS release by interruption of the hepatic parasympathetic nerves by surgical denervation, atropine, or blockade of hepatic nitric oxide synthase produced similar degrees of insulin resistance and revealed a similar dynamic pattern of hormone action that began 3--4 min after, and continued for 9--10 min beyond, insulin action (50 mU/kg). HISS action accounted for 56.5 +/- 3.5% of insulin action at insulin doses from 5 to 100 mU/kg (fed). We also tested the hypothesis that HISS release is controlled by the feed/fast status. Feeding resulted in maximal HISS action, which decreased progressively with the duration of fasting.  (+info)

Nitric oxide-dependent in vitro secretion of amylase from innervated or chronically denervated parotid glands of the rat in response to isoprenaline and vasoactive intestinal peptide. (7/71)

The basal in vitro release of amylase was similar from rat parotid lobules of innervated and chronically denervated glands and was unaffected by the inhibitors used in this study. The secretion of amylase induced by isoprenaline or vasoactive intestinal peptide (VIP) was reduced by one-third to one-half from the lobules of the innervated glands and even more so from the lobules of the denervated glands by ODQ, an inhibitor of soluble guanyl cyclase which is activated by nitric oxide (NO) and catalyses the cGMP production. The use of N (omega)-propyl-L-arginine (N-PLA) revealed that the evoked secretion of amylase in the denervated glands depended on the activity of neuronal type NO synthase to synthesize NO. Since the denervated gland is virtually devoid of NO synthase-containing nerve fibres, the neuronal type NO synthase was most probably of a non-neuronal source. NO-dependent amylase secretion was agonist related, since amylase secretion evoked by bethanechol and neuropeptide Y was not reduced by ODQ or N-PLA. Hence, under physiological conditions, activation of beta-adrenoceptors (sympathetic activity) and VIP receptors (parasympathetic activity) is likely to cause secretion of parotid amylase partly through a NO/cGMP-dependent intracellular pathway involving the activity of neuronal type NO synthase, possibly of acinar origin.  (+info)

Heartbeat control in leeches. II. Fictive motor pattern. (8/71)

The rhythmic beating of the tube-like hearts in the medicinal leech is driven and coordinated by rhythmic activity in segmental heart motor neurons. The motor neurons are controlled by rhythmic inhibitory input from a network of heart interneurons that compose the heartbeat central pattern generator. In the preceding paper, we described the constriction pattern of the hearts in quiescent intact animals and showed that one heart constricts in a rear-to-front wave (peristaltic coordination mode), while the other heart constricts in near unison over its length (synchronous coordination mode) and that they regularly switch coordination modes. Here we analyze intersegmental and side-to-side-coordination of the fictive motor pattern for heartbeat in denervated nerve cords. We show that the intersegmental phase relations among heart motor neurons in both coordination modes are independent of heartbeat period. This finding enables us to combine data from different experiments to form a detailed analysis of the relative phases, duty cycle, and intraburst spike frequency of the bursts of the segmental heart motor neurons. The fictive motor pattern and the constriction pattern seen in intact leeches closely match in their intersegmental and side-to-side coordination, indicating that sensory feedback is not necessary for properly phased intersegmental coordination. Moreover, the regular switches in coordination mode of the fictive motor pattern mimic those seen in intact animals indicating that these switches likely arise by a central mechanism.  (+info)

*Familial amyloid neuropathy

July 2006). "Impact of liver transplantation on cardiac autonomic denervation in familial amyloid polyneuropathy". Medicine ( ... The aggregation of one precursor protein leads to peripheral neuropathy and/or autonomic nervous system dysfunction. These ... are a rare group of autosomal dominant diseases wherein the autonomic nervous system and/or other nerves are compromised by ... wild type and different mutant subunits against amyloidogenesis halting the progression of peripheral neuropathy and autonomic ...

*Neural top-down control of physiology

"Autonomic Renal Denervation Ameliorates Experimental Glomerulonephritis". Journal of the American Society of Nephrology. 19 (7 ... Love, J. A.; Yi, E.; Smith, T. G. (2007). "Autonomic pathways regulating pancreatic exocrine secretion". Autonomic Neuroscience ... Edwards, A. V.; Jones, C. T. (1993). "Autonomic control of adrenal function". Journal of Anatomy. 183 (Pt 2): 291-307. PMC ... Nance, D. M.; Sanders, V. M. (2007). "Autonomic innervation and regulation of the immune system (1987-2007)". Brain, Behavior, ...

*List of MeSH codes (E04)

... denervation MeSH E04.525.210.080 --- autonomic denervation MeSH E04.525.210.080.600 --- parasympathectomy MeSH E04.525.210.080. ... muscle denervation MeSH E04.525.210.550 --- nerve block MeSH E04.525.210.560 --- nerve crush MeSH E04.525.210.700 --- rhizotomy ...

*Nerve injury

Denervation changes recorded by EMG are the same as those seen with axonotmetic injury. There is a complete loss of motor, ... This type of nerve damage may cause paralysis of the motor, sensory, and autonomic. Mainly seen in crush injury. If the force ... There is frequently greater involvement of motor than sensory function with autonomic function being retained. In ... Electromyography ( EMG ) performed 2 to 4 weeks later shows fibrillations and denervation potentials in musculature distal to ...

*Medullipin

This hypotensive response depends on an intact renal medulla and is not altered by renal denervation or the inhibition of the ... renin-angiotensin system (RAS) or autonomic nervous function Gothberg, 1994 - Gothberg G. Physiology of the renomedullary ...

*Paroxysmal sympathetic hyperactivity

At the time, her episodes were termed 'diencephalic autonomic epilepsy'. It was believed that both her sympathetic and ... The future may hold non-pharmacologic solutions such as renal sympathetic denervation. Perkes, Iain; Baguley, Ian J.; Nott, ... doi:10.1007/s10286-012-0184-4. Singh, DK; Singh, N (September 2011). "Paroxysmal Autonomic Instability with Dystonia in a Child ... Blackman, James A.; Patrick, Peter D.; Buck, Marcia L.; Rust, Jr, Robert S. (2004). "Paroxysmal Autonomic Instability With ...

*Fritz Köberle

Köberle and his group of collaborators were able to prove that they were caused also by an extensive denervation of the ... by extensively quantifying the number of neurons of the autonomic nervous system in the Auerbach's plexus, that: 1) they were ... characterizing it as a disease of the autonomic nervous system, which establishes itself during the acute phase and provokes ... long term and slowly installing denervation. Since the trypanosoma does not seem to damage neurons directly, Köberle and other ...

*Orthostatic hypotension

It is also present in many patients with Parkinson's disease resulting from sympathetic denervation of the heart or as a side- ... This rarely leads to fainting unless the person has developed true autonomic failure or has an unrelated heart problem.[ ... There are numerous possible causes for orthostatic hypotension, such as certain medications (e.g. alpha blockers), autonomic ... ISBN 978-0-07-180215-4. Idiopathic Orthostatic Hypotension and other Autonomic Failure Syndromes at eMedicine "What Causes ...

*Endoscopic thoracic sympathectomy

The autonomic nervous system is not anatomically exact and connections might exist which are unpredictably affected when the ... Goebel, F.-D.; Füessl, H.S. (1983). "Mönckeberg's sclerosis after sympathetic denervation in diabetic and non-diabetic subjects ... The autonomic nervous system. [Amsterdam, Netherlands]: Elsevier Science Publishers. p. 110. ISBN 0-444-82812-5. Bassenge, E; ... ETS patients are being studied using the autonomic failure protocol headed by David Goldstein, M.D. Ph.D., senior investigator ...

*Diabetic cardiomyopathy

Therefore, the diabetic heart shows clear denervation as the pathology progresses. This denervation correlates with ... The autonomic innervations of the myocardium in diabetic cardiomyopathy are altered and contribute to myocardial dysfunction. ... While the heart can function without help from the nervous system, it is highly innervated with autonomic nerves, regulating ... Other causes of denervation are ischemia from microvascular disease and thus appear following the development of ...

*Postural orthostatic tachycardia syndrome

A variety of autonomic tests are employed to exclude autonomic disorders that could underlie symptoms, while endocrine testing ... Another subtype, neuropathic POTS, is associated with denervation of sympathetic nerves in the lower limbs. In this subtype, it ... Sandroni, P; Low, PA (12 March 2009). "Other autonomic neuropathies associated with ganglionic antibody". Autonomic ... In cases where a particular associated condition or complicating factor are suspected, other non-autonomic tests may be used: ...

*Adie syndrome

Additionally, patients with Holmes-Adie Syndrome can also experience problems with autonomic control of the body. This second ... pilocarpine may constrict the tonic pupil due to cholinergic denervation supersensitivity. A normal pupil will not constrict ... and affects the pupil of the eye and the autonomic nervous system. Adie syndrome presents with three hallmark symptoms, namely ...

*Spinal shock

Autonomic dysreflexia is permanent, and occurs from Phase 4 onwards. It is characterized by unchecked sympathetic stimulation ... The reason reflexes return is the hypersensitivity of reflex muscles following denervation - more receptors for ... In spinal cord injuries above T6, neurogenic shock may occur, from the loss of autonomic innervation from the brain. ...

*Minimaze procedure

The autonomic nerves (ganglionated plexi) that may cause AF may be eliminated as well. Subsequently the left side of the chest ... "Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation". ... A concept gaining support is that paroxysmal AF is mediated in part by the autonomic nervous system and that the intrinsic ... Supporting this is the finding that targeting these autonomic sites improves the likelihood of successful elimination of AF by ...

*Substance P

This, ultimately, leads to a condition known as denervation supersensitivity as the post-synaptic nerves will become ... and general autonomic discharge. The actions of aprepitant are said to be entirely central, thus requiring passage of the drug ...

*Facial feedback hypothesis

"Effects of Nonverbal Dissimulation on Emotional Experience and Autonomic Arousal". Journal of Personality and Social Psychology ... Facial Feedback and Neural Activity within Central Circuitries of Emotion-New Insights from Botulinum Toxin-Induced Denervation ...

*Ciliary ganglion

Both of these muscles are involuntary - they are controlled by the autonomic nervous system. It is one of four parasympathetic ... 4) Denervation supersensitivity. Like any denervated muscle, the iris becomes supersensitive to its normal neurotransmitter (in ...

*Neuromuscular junction

Examples of autonomic dysfunction caused by LEMS include erectile dysfunction in men, constipation, and, most commonly, dry ... By doing so, it induces a transient flaccid paralysis and chemical denervation localized to the striated muscle that it has ... This rare disease can be marked by a unique triad of symptoms: proximal muscle weakness, autonomic dysfunction, and areflexia. ...

*Neuromodulation (medicine)

In 1973, Hosbuchi reported alleviating the denervation facial pain of anesthesia dolorosa through ongoing electrical ... the global pharmaceutical company GlaxoSmithKline announced an initiative in bioelectric medicine in which the autonomic ...

*Urination

The muscles controlling micturition are controlled by the autonomic and somatic nervous systems. During the storage phase the ... The hyperactive state in the former condition suggests the development of denervation hypersensitization even though the ... Physiologically, urination involves coordination between the central, autonomic, and somatic nervous systems. Brain centers ...

*Chronaxie

... "long-term denervation stage" of the rat model, i.e., denervation time longer than six months). In 3 out of 36 leg muscles, ... the physiological factors responsible for this change being under the influence of the autonomic nervous system. This example ... Chronaxie from 0.1-0.2 ms in innervated muscle changed to 0.5-1 ms within one to two days after denervation (i.e., after ... Chronaxie remained at this level up to 6 months postsciatectomy (Mid-term denervation stage in the rat model: from 2 to 6 ...

*Hyperhidrosis

Reisfeld, Rafael (2006). "Sympathectomy for hyperhidrosis: Should we place the clamps at T2-T3 or T3-T4?". Clinical Autonomic ... Some patients have experienced cardiac sympathetic denervation, which can result in a 10% decrease in heart rate both at rest ... In people with a past history of spinal cord injuries Autonomic dysreflexia Orthostatic hypotension Posttraumatic syringomyelia ... Associated with peripheral neuropathies Familial dysautonomia (Riley-Day syndrome) Congenital autonomic dysfunction with ...

*Epigenetics of neurodegenerative diseases

The main group of sensory neuron diseases are hereditary sensory and autonomic neuropathies (HSAN) such as HSAN I, HSAN II, and ... it did not increase lifespan or prevent denervation (Rouaux et al., 2007). Human trials of valproic acid in ALS patients did ... and motor neuron loss and denervation were halted (Riessland et al., 2010). No human trials have been conducted. Main Wiki ... nourishment in early onset mouse SMA models resulted in improved motor function and survival and delays progressive denervation ...

*History of catecholamine research

I find that even after … complete denervation, whether of three days' or ten months' duration, the plain muscle of the ... ISBN 0-387-05517-7. H. H. Dale (1934). "Nomenclature of fibres in the autonomic system and their effectsle". The Journal of ... Clinical Autonomic Research. 9 (3): 145-149. doi:10.1007/BF02281628. PMID 10454061. Josef Donnerer, Fred Lembeck: Adrenaline, ... the so-called myoneural junctions connected with the true sympathetic or thoracic-lumbar division of the autonomic nervous ...

*Physical exercise

Carter, JB; Banister, EW; Blaber, AP (2003). "Effect of endurance exercise on autonomic control of heart rate". Sports Medicine ... and NF-κB-dependent gene transcription during muscle atrophy that is induced by fasting or denervation; thus, PGC-1α may be a ...
After obtaining informed consent patients will undergo to basal electrophysiological study (EPS) to record AH interval, HV interval, Wenckebach cycle length, sinus node recovery time (SNRT) and correct sinus node recovery time (cSNRT); the same parameters will be recorded immediately after ablation. Following basal EPS an accurate (200 valid points at least) electroanatomic right atrium mapping (CARTO 3™ Biosense Webster, Inc) will be performed and subsequently radiofrequency delivered at right atrial anatomic sites where the underlying presence of ganglionated plexi (GPs) clusters was regarded as highly probable, on the basis of anatomical studies [8-11]: the supero-posterior area (superior right atrial GP, adjacent to the junction of the superior vena cava and the posterior surface of RA), the middleposterior area (posterior right atrial GP, posterior surface of the RA adjacent the interatrial groove), the infero-posterior area (inferior right GP placed between the inferior vena cava, ...
This is a clinical study looking at the effectiveness and safety of a new device call The Paradise System to use for renal denervation in patients who have mild to resistant hypertension. The study is divided into two groups, those on one to two anti hypertensive medications and those on three or more. For those only taking one or two medications, they will stop their current blood pressure medication while monitoring their blood pressure. Those who are taking 3 or more blood pressure medications will stop their current medication regime and be given one of two combination medications while monitoring their blood pressure. In each of the groups have the patients, if and when they continue to meet study inclusion criteria, will be randomized to undergo a renal denervation procedure using the new system vs no procedure. Their assignment will not be made known to them. All groups will be follow up to 3 years but for patients who did not initially have the procedure will be allowed to do so after ...
In SPYRAL HTN OFF-MED renal denervation patients, the 24-hour systolic ambulatory blood pressure (ABPM) declined 5.5mmHg, resulting in a 5mmHg difference from the sham control arm (p=0.041), and the diastolic AMBP declined 4.8mmHg, resulting in a 4.4mmHg difference from the sham control arm (p=0.002). Additionally, there were no reported cases of new or worsening renal failure, vascular complications, or other major adverse events, confirming the safety of the renal denervation procedure - even with a revised procedural approach that extended ablations into the kidneys branch arteries and an increase in total number of ablations compared with previous trials.. "After SYMPLICITY HTN-3, we learned a lot about the procedure itself, medication adherence and which patients may have less response to the renal denervation procedure-these insights have been incorporated into the revised clinical approach in the SPYRAL HTN program," said co-principal investigator David Kandzari, director of ...
The results of the present study support the conclusion that in rats, the arterial baroreceptor reflex largely mediates the stress-induced increases in Mayer waves and associated RSNA oscillations. In rats with chronic SAD, stress enhances fluctuations of MAP and RSNA in the frequency band containing Mayer waves but does not unmask any predominant rhythmicity at Mayer waves frequency.. In baroreceptor-intact and SAD rats, a continuous jet of air blown into the cage increased RSNA and MAP, which is characteristic of the defense reaction in rats.26,27 In SAD rats, although the stress-induced increase in RSNA was similar to that observed in control rats, the increase in MAP was larger. The latter finding accords with a previous report.22 These differential effects of stress on MAP were not related to cardiac factors because the autonomic innervation of the heart had been blocked. Stress did not markedly alter the gain of the transfer function between RSNA and MAP in SAD rats, which suggests that ...
Used for soft tissue core biopsy. Facilitates one-handed operation during procedural use. Etched tip enhances visualization during ultrasound imaging. Precise, rapid firing spring mechanism provides intact core tissue sample. Bevelled point stylet permits easy penetration into the specimen with less trauma to surrounding tissue.
I would like to build my own reservoir using Lexan or Plexi from my local home depot. Would any of you with any experience be able to recommend a good method or guide...
Endometriosis" describes deposits of ectopic endometrium outside the uterus. Traditionally, gynaecologists believe that these "deposits" of endometrium bleed during your period and cause pain. A better view is that the pain is caused by injuries to your pelvic nerves. These injuries are caused by difficult first labours, straining on the loo, and, gynaecological surgery (GS Atwal, 2005).. "Endometriosis" was first described in 1860 though it has had many reincarnations since that date. The theory associated with deposits of ectopic endometrium has, therefore, had 150 years to cement itself into medical minds and habits. Injured nerves were discovered in 2005 ! So it is going to take a little while to change hearts and minds ? And it is not going to be easy because many doctors make enormous sums of money ablating, or excising, ectopic endometrium.. What is the evidence that ectopic endometrium causes "cyclical, premenstrual pain" ? There is NONE. But that does not stop muti-disciplinary teams of ...
A renal denervation system includes an ablation catheter and an inflation balloon. The renal denervation catheter is insertable into a renal artery to perform a renal denervation procedure. The inflation balloon is inflatable within the renal artery, wherein one of a blood pressure condition in the renal artery resulting from operation of the inflation balloon and a performance characteristic of the inflation balloon indicates efficacy of the renal denervation procedure.
Despite large reductions in blood pressure seen in early studies of renal denervation, the SYMPLICITY HTN-3 randomized trial failed to show a reduction in systolic blood pressure with renal denervation when compared to medical therapy alone. As a result, interest in renal denervation as a treatment for resistant hypertension has waned. In the DENERHTN trial, Azizi and colleagues assessed the incremental benefit of adding renal denervation to standardized stepped-care antihypertensive treatment (SSAHT) for patients with resistant hypertension in an open-label, randomized-controlled trial with blinded endpoint evaluation. After four weeks of a standardized anti-hypertensive regimen to confirm resistant hypertension, patients were randomized to renal denervation in addition to SSAHT versus SSAHT alone. The primary endpoint was the mean change in daytime systolic blood pressure after six months as assessed by ambulatory monitoring. Of the 106 patients randomized (53 in each group), 101 had endpoints ...
LAGUNA HILLS, Calif., Jan. 18, 2012 /PRNewswire/ -- Vessix Vascular, Inc., a developer of novel percutaneous radiofrequency (RF) balloon catheter technology, announced today that the first public presentation of its new percutaneous V2 Renal Denervation System™ for the treatment of medication-resistant hypertension will be made at LINC 2012 in Leipzig, Germany on Thursday, January 26, 2012. Renal denervation is a new percutaneous catheter-based technique for the treatment of medication resistant or uncontrolled hypertension. The new V2 Renal Denervation System is designed to be faster, easier to deploy and less invasive for the patient than the alternatives available today in the market.. The presentation, titled "Radiofrequency balloon-mediated renal denervation: The V2 Catheter by Vessix Vascular," will be made by Prof. med. Horst Sievert during a session for new emerging technologies for renal denervation chaired by Krishna Rocha-Singh, M.D.. Dr. Sievert, a globally recognized ...
Renal denervation with ultrasound after performed after prior denervation with radiofrequency seems to be safe. After an initial decrease of blood pressure after one month, we observed an increase in blood pressure in this small number of patients, a finding which has not been seen in other denervation studies," said Sievert.. RETREAT is a physician-initiated prospective, multicentre study with no industry funding in which 30 patients will be enrolled. Its purpose is to evaluate the effect of renal denervation using ultrasound energy (with Recors Paradise system) after failed denervation with radiofrequency (with Medtronics Symplicity system).. Sievert said: "Enrolment in the RETREAT study coincided with the publication of the SYMPLICITY HTN-3 study results following which the reimbursement for renal denervation was stopped in Germany. There was a decline in referrals for renal denervation and new treatment modalities for hypertension began to be explored. This resulted in enrolment becoming ...
Covidien [1] plc has announced it will exit its OneShot Renal Denervation program. This voluntary action is primarily in response to slower than expected development of the renal denervation market.. The OneShot system is an over-the-wire balloon-based irrigated catheter technology for the treatment of hypertension. The system received CE Mark in February 2012 and is not approved for sale in the United States.. This decision resulted from Covidiens regular review of strategic programs and growth potential for various aspects of its product portfolio.. As a result of this decision the company will not proceed with its RAPID II randomized study. Additionally, Covidien expects to record after-tax charges in the range of $20 to $25 million as a result of exiting the OneShot program.. Over the next several weeks, the company will collaborate with physicians and the renal denervation community to ensure existing OneShot patients are informed and the currently enrolling clinical trials are ...
The Symplicity HTN-3 study is a, multi-center, prospective, single-blind, randomized, controlled study of the safety and effectiveness of renal denervation in subjects with uncontrolled hypertension. Bilateral renal denervation will be performed using the Symplicity Catheter - a percutaneous system that delivers radiofrequency (RF)energy through the luminal surface of the renal artery ...
Renal Denervation in CKD Hypertensive Patients: Would it be Possible to Prevent the Development of Risk Factors Responsible for Sudden Cardiac Death in this Population?
This site is meant for educational purposes only no medical advice is given or implied. Renal denervation is still an experimental treatment in many parts of the world, including the United States.. If you are already registered,please enter your email here.. ...
Since Alger Hiss was convicted at his second trial for perjury in 1950, most of the books on the Hiss-Chambers case have been written by partisans of Hiss who believe he was framed; and most have largely rehashed the very evidence available at the trials, using it to attack Chamberss defense of himself in his book Witness. Important new evidence on the case has now become available-not only from FBI and other government files that were previously classified but from the defense records that Hiss himself has opened to me and to other researchers, including John Chabot Smith, the author of Alger Hiss: The True Story.. Unfortunately, Smiths book follows the familiar pattern. He uses little of the new material released by the government. What is worse, he fails even to mention many of the documents in Hisss own files that undermine Hisss claims to have told the truth. Smith tells us that he covered the two Hiss trials for the New York Herald Tribune and has believed ever since that Hiss was the ...
PISS" is my memory aid for remembering, Parasympathetics make you Pee from S2 - S4 segments. (Two Ss in piss, so S2). So the opposite, sympathetic L1 and L2, allow urine to collect and are inhibitory to the detrusor muscle. Thats all ...
Unfortunately, the HarrisвBenedict equations have been used to predict energy requirements in diverse groups of patients.inadequate mucosal stimulation, altered djelov anje production, inhibitors to neurotransmission) can result in diminished gut motility. Super kamagra djelovanje observation implies a close theoretical connection between the computation of distance from motion and distance from binocular disparity.
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Clinical trial for Diabetes and Hypertension | High Blood Pressure (Hypertension - Pediatric) | Vascular Diseases | High Blood Pressure (Hypertension) | Cardiovascular Disease | Hypertension , Renal Denervation on Quality of 24-hr BP Control by Ultrasound In Resistant Hypertension
The effect of supradiaphragmatic splanchnicectomy on the blood pressure of 294 hypertensive patients followed for 10 to 18 months after surgery is compared with the effects of nonspecific medical management in a control group of 79 patients similarly studied. The data are presented in simple graphic form. It is concluded that 29 per cent of the hypertensive patients had reductions in blood pressure outside the range of spontaneous variation, that the vascular complications of hypertension decreased the likelihood of a good result, and that extension of the sympathetic ganglionectomy upward appeared to increase the frequency of good results without requiring a two-stage operation or producing significant postoperative orthostatic hypotension.. ...
The CE mark enables Vessix to market its patented V2 System throughout the European Union. The CE certification was issued to Vessix by its notified body, BSI Group, also known as the British Standards Institution.. "Vessix offers a unique approach to treating uncontrolled hypertension that provides excellent clinical results and is faster, easier to use and less painful for patients than any renal denervation system currently available in the market," said CEO Raymond W Cohen. "After eight years optimising radiofrequency balloon catheter and bipolar radiofrequency generator technologies, it is rewarding to see the V2 System working effectively in clinical practice to safely reduce patient blood pressures. As part of our commercialisation strategy, Vessix has initiated a post-market approval surveillance study during which we plan to treat 120 patients at up to 20 international centers located across Western Europe.". Renal denervation has shown in published clinical studies to be safe, durable ...
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Costello, J.P., Wilson, J.K., Louis, C., Peer, S.M., Zurakowski, D. et al. (2015). Surgical cardiac denervation therapy for treatment of congenital ion channelopathies in pediatric patients: a contemporary, single institutional experience. World Journal of Pediatric and Congenital Heart Surgery, 6(1), 33-38.. ...
Renal sympathetic denervation (RSDN), or renal denervation (RDN), is a minimally invasive, endovascular catheter based procedure using radiofrequency ablation or ultrasound ablation aimed at treating resistant hypertension (high blood pressure not controlled by medication).
Results Systolic blood pressure after catheter-based renal denervation decreased by 35.52 ± 17.65, 36.63 ± 18.54 mmHgat 6 months and 1 year, respectively (P , 0.001). Diastolic blood pressure decreased by 15.19 ± 15.44, 16.13 ± 15.51 mmHg, at 6 months, and 1 year, respectively (P , 0.001). Meanwhile, there is a clear positive correlation between NE and the BP reduction (r2 = 0.82, P , 0.001), and a similar correlation between rennin (r2 = 0.72, P , 0.001), AngII (r2 = 0.75, P , 0.001), ALD (r2 = 0.71, P , 0.001), ET-1 (r2 = 0.72, P , 0.001) and the BP reduction was observed in our study. In addition, there is a significantly decline in NE, renin, AngII, ALD and ET-1 (all P , 0.01).. ...
Looking for online definition of Hiss stain in the Medical Dictionary? Hiss stain explanation free. What is Hiss stain? Meaning of Hiss stain medical term. What does Hiss stain mean?
why do cats hiss - 28 images - pet safety tips st patricks day, hissing cat www imgkid the image kid has it, cat behavior why cats hiss, all about cat hissing why do cats hiss catster, why do cats hiss 1 800 petmeds cares
This is mine. The basking spot itself is a piece of ceramic tile cut to size to rest on the rim of the tank, and his floating dock acts as a ramp for him to climb up on. The rest is just a box that fits down around the outside of the tank with stops at the corners to hold it in place. Im not sure how the plexiglass is done in the front, my dad got creative with that part, and it looks like he somehow built that part around the plexi. Im sure you could just glue or screw a piece of plexi in place ...
This is mine. The basking spot itself is a piece of ceramic tile cut to size to rest on the rim of the tank, and his floating dock acts as a ramp for him to climb up on. The rest is just a box that fits down around the outside of the tank with stops at the corners to hold it in place. Im not sure how the plexiglass is done in the front, my dad got creative with that part, and it looks like he somehow built that part around the plexi. Im sure you could just glue or screw a piece of plexi in place ...
Introduction: Esophageal injury is a potential complication after catheter ablation of the posterior left atrium (LA). Therefore, we describe a new approach for complete isolation of the posterior LA including all pulmonary veins (PVs) without vertical lesions along the esophageal aspect of the posterior LA, namely Box isolation.. Methods and Results: Ninety-one patients with paroxysmal atrial fibrillation (AF) underwent Box isolation. Continuous lesions at the anterior portions of the ipsilateral PVs were initially created and then linear ablation of LA roof and bottom was performed to isolate the posterior LA. Continuous vertical lesions at the posterior portions of PVs along the esophageal aspect of the posterior LA were not created. Ablation was performed with an 8-mm-tip catheter. The endpoint was the absence of electrical activity and the inability to pace the posterior LA and all PVs in sinus rhythm. Complete isolation of the posterior LA was achieved in 82 patients (90%). Ablation ...
Renal nerve ablation has been shown to elicit a chronic, anti-hypertensive effect in drug-resistant hypertensive patients. Precise understanding of the mechanisms underlying the clinical success of renal denervation is currently unknown, and as a consequence, it is predicted the technology will be under-utilized until such information is uncovered. Retrospective multivariate analyses of responders suggest treatment with a central sympatholytic may correlate with a successful response to renal denervation. However, this hypothesis remains untested. This study tested the hypothesis that pretreatment with a central sympatholytic would augment the response to renal denervation (RDX) in the spontaneously hypertensive rat. In rats pre-treated for 1 week with clonidine (125ug/kg/day), MAP was significantly reduced from baseline but there was no difference in response to clonidine between groups (Sham(n=7): -21.3±0.8 vs RDX(n=7): -22.8±1.3mmHg, p,0.05). During clonidine treatment RDX significantly ...
OBJECTIVE We have previously demonstrated the effectiveness of renal denervation (RDN) to lower blood pressure (BP) at least partially via the reduction of sympathetic stimulation to the kidney. Obesity also contributes to hypertension. A number of adipocyte-derived factors (collectively termed adipokines) have been implicated in BP control. The aim of this study was to examine the effect of RDN on adipokines. In particular, whether BP reduction, associated with RDN treatment, has a favourable outcome on adipokine profile in patients with resistant hypertension (RH). DESIGN AND METHOD Fifty seven patients with RH undergoing RDN have been recruited for the study (65% males, age 60.8 ± 1.5 years, BMI 32.6 ± 0.7 kg/m, mean ± SEM). At recruitment the patients were on an average of 4.8 ± 2.1 antihypertensive drugs and were asked to refrain from changing their medication regimen for the duration of the study. Automated seated office BP measurements were taken with an Omron HEM-705 monitor at baseline
Vasovagal syncope is a benign condition. According to the recent recommendations of the ESC Guidelines on Syncope (3) the patients who seek medical advice after having experienced a vasovagal faint require principally reassurance and education regarding the nature of the condition. In general, initial treatment of all forms of neurally-mediated reflex syncope comprises education regarding avoidance of triggering events (e.g., hot crowded environments, volume depletion, effects of cough, tight collars, etc.), recognition of premonitory symptoms, and manoeuvers to abort the episode. Non-pharmacological "physical" treatments are arising as a new first choice treatment of vasovagal syncope in patients who have vasovagal syncope preceded by prodromal symptoms and age ,65 years. This approach seems to be very helpful in real life. In 2 follow-up studies (1,2), the manoevres were self-administered by these patients in ,95% of cases and were able to abort syncope in ,95% of patients. No patients had ...
The prevalence of resistant hypertension in this primary care setting is 8.8%. This is lower than that reported in secondary care [8, 32, 33] but is similar to another primary care study [18].. Our findings also show that hypertensive patients with CKD had 2.9 odds of having resistant hypertension compared to those without CKD. This is consistent with findings in other studies [12, 14]. One possible reason is that in patients with CKD, there is increased sensitivity to salt resulting in sodium and fluid retention, thus making BP more difficult to control [34]. Another possible explanation is that in CKD, the RAS system is up regulated resulting in difficult to control BP [35].. Our study sample is made up of older patients as seen from the mean age of 66.9 years. That resistant hypertension is negatively associated with age could be due to the survival effect of fitter patients, whereby those with resistant hypertension had already succumbed to the complications of uncontrolled or resistant ...
Posted By Marie on November 17, 1998 at 10:32:40: In Reply to: Re: Vasovagal syncope posted by CCF CARDIO MD - MTR on November 17, 1998 at 01:34:12: I wrote on October 7th, 1998, and re...
We found that the lengths of all sarcomeres spontaneously oscillated in an isolated skeletal myofibril, when both ends were fixed, submillimolar to millimolar concentrations of ATP, ADP and inorganic...
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Visit Healthgrades for information on Dr. Paul Hiss, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
I open the door and shes waiting, but usually greats me with a hiss. She will approach me, but Im not allowed to approach her. I have to be careful when I set down the food because shell come over to get it, but scratch me at the same time. So, shes kind of used to people. Normally ferals wont come close and will hide until the food is set out. This all leads me to believe she probably was socialized with humans early in her life and then abandoned and became feral. Her contact with humans was probably only for a short period of time, but long enough that she isnt totally freaked out around them. However, she has taught her kittens well. Whenever she hisses they run and hide. I might have tried to catch and tame them when I realized the gray and white one was coming around, but that was during the time I was taking Reid down for radiation every day and it just wasnt possible. So, well just try and give them the best life possible ...
Mario you sound like my brother! I feel I do have symptoms tho bc I have all the twitching and now 4 limbs with denervation. I think the neuro didnt give details bc he wanted me to move on and feel well even if down the road things got worse. I ruined that by pushing questions on him and now I have details I wish I didnt ...
About hypertension. Hypertension is a chronic medical condition in which blood pressure in the arteries is elevated. Blood pressure is expressed by two measurements, systolic and diastolic pressures, which are the maximum and minimum pressures, respectively, in the arterial system. Normal blood pressure at rest is within the range of 100-140 mmHg systolic and 60-90 mmHg diastolic. Hypertension is present if the blood pressure is persistently at or above 140/90 mmHg for adults. Sustained hypertension over time is a major risk factor for heart disease, coronary artery disease, stroke, aortic aneurysm, peripheral artery disease and chronic kidney disease. Hypertension affects over 1 billion people worldwide.. About renal denervation. Renal denervation is an interventional approach for the treatment of high blood pressure. A minimally-invasive, endovascular-catheter-based procedure, it uses radiofrequency or ultrasound ablation to treat resistant hypertension. Nerves in the wall of the renal artery ...
Treatment of Syncope (commonly referred to as fainting) is a loss of consciousness that occurs when you experience a significant reduction of blood flow to your brain. Fainting is often caused by a significant drop in blood pressure or from a very slow heart rate. The result is a sudden reduction of blood flow to your brain, causing you to lose consciousness, The most common cause of fainting is due to vasovagal syncope. Vasovagal syncope is triggered by a stimulus that results in an exaggerated and inappropriate response in the part of your nervous system that regulates involuntary body functions, including heart rate and blood flow (autonomic nervous system). When some sort of stimulus triggers this exaggerated response, both your heart rate and blood pressure drop, quickly reducing blood flow to your brain and leading to loss of consciousness. A person who has fainted due to vasovagal syncope recovers quickly, usually within seconds or a few minutes, Common triggers of vasovagal syncope include
... is a condition that is characterized by a temporary loss of consciousness. The condition occurs when an individual is exposed to stressful or overwhelming experiences. (i.e. sight of blood, fear, overheated, etc.) The vagus nerve is responsible for sending messages from the brain to the heart and digestive tract. When this nerve becomes over stimulated, the body encounters a sudden drop in blood pressure, and consequently there is reduced blood flow to the brain and ultimately loss of consciousness.. Common symptoms of vasovagal syncope may include light-headedness, temporary loss of color vision, dizziness, weakness, and fainting. Generally, individuals who suffer from a single episode of vasovagal syncope do not have any underlining heart problems. However, if the fainting occurs frequently, it is necessary to contact a doctor to examine your personal situation further. Although there is no cure for vasovagal syncope, there are many treatment options to prevent future ...
A method is provided for rapid firing at low temperatures to remove impurities from the semiconductor surface prior to deposition in situ. Advantageously, the short time low temperature process consumes very little thermal expense, making the process suitable for modern high density circuits with shallow junctions. In addition, the throughput is greatly improved by low temperature firing, especially in combination with low temperature plasma cleaning and low temperature wafer loading prior to firing, and deposition at lower temperatures than conventional epitaxial deposition after firing. The process enables epitaxial deposition of a silicon containing layer on a semiconductor surface, in particular epitaxial deposition on a silicon germanium base layer. By using low temperature firing, the silicon germanium base layer can be cleaned to facilitate further epitaxial deposition without relaxing the strained crystal structure of silicon germanium. Semiconductor Substrates, Silicon
How can you boost brain power? It s an important question to ask, especially with the rise of dementia and Alzheimer s diseases. Is there really anything that can be done to achieve optimal brain health in an effort to ward off these debilitating diseases? Indeed there is! Reuters recently reported on a study that found more and more physical exercises are proving useful for brain health. Tai Chi seems to dominate the cognitive function category. But they re definitely not alone which is great news for people who like activities that are more energetic. A variety of strength training and aerobic exercises have been shown to slow cognitive decline in adults over the age of 50. Neurons in the brain fire whenever people are engaged in a form of physical activity. Even something like walking regularly can have a profound effect on brain function. The neurons in the brain fire whenever people have to balance and contract their muscles. Not only does the rapid firing help the body to perform these ...
The management of hypertension remains a significant challenge and requires a multi-faceted approach that includes addressing lifestyle factors, prescribing anti-hypertensives and ruling out secondary causes. However despite the availability, efficacy and safety of anti-hypertensive medications, a significant proportion of hypertensive patients do not meet blood pressure (BP) targets recommended in national guidelines [2]. Patients in whom BP is elevated despite three anti-hypertensive medications of different classes are described as having resistant hypertension . These patients represent over 10% of the hypertensive population and are 50% more likely to experience a cardiovascular event than the general hypertensive population [2, 3]. It is therefore not difficult to understand why there has been significant interest in interventional procedures, such as renal denervation, in BP management.. Renal denervation: The concept. Experimental studies in animals and humans with hypertension have ...
my mom is 80 years old and she has a pacer maker since 7 years ago. She is hypertensive and arrythmic. she fainted some 3 months ago due to vasovagal syncope. she is monitored to have very low blood pr...
3. Compare and contrast these action potentials, in terms of ionic changes, the various ion channels and the effect of autonomic innervation on electrical changes ...
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i noticed on a boat similar to mine they have a solar vent in their forward hatch - old style bomar with tinted plexi - already have a leak to repair at caulking between plexi and alum frame. can
Increased sympathetic activity is a well-known pathophysiological mechanism in insulin resistance (IR) and hypertension (HT). The carotid bodies (CB) are peripheral chemoreceptors that classically respond to hypoxia by increasing chemosensory activity in the carotid sinus nerve (CSN), causing hyperventilation and activation of the sympathoadrenal system. Besides its role in the control of ventilation, the CB has been proposed as a glucose sensor implicated in the control of energy homeostasis. However, to date no studies have anticipated its role in the development of IR. Herein, we propose that CB overstimulation is involved in the etiology of IR and HT, core metabolic and hemodynamic disturbances of highly prevalent diseases like the metabolic syndrome, type 2 diabetes, and obstructive sleep apnoea. We demonstrate that CB activity is increased in IR animal models and that CSN resection prevents CB overactivation and diet-induced IR and HT. Moreover, we show that insulin triggers CB, ...
TY - JOUR. T1 - Treating resistant hypertension now and in the future. AU - Sata, Yusuke. AU - Xu, Jianzhong. AU - Hering, Dagmara. AU - Schlaich, Markus. PY - 2013. Y1 - 2013. N2 - Treatment of resistant hypertension is a priority because patients with nonoptimal blood pressure are at high risk for major cardiovascular events. Pharmacological advances include the use of aldosterone antagonists and the development of several new strategies. Device-based therapies such as catheter-based renal denervation and electrical stimulation of baroreceptors are showing promising results.. AB - Treatment of resistant hypertension is a priority because patients with nonoptimal blood pressure are at high risk for major cardiovascular events. Pharmacological advances include the use of aldosterone antagonists and the development of several new strategies. Device-based therapies such as catheter-based renal denervation and electrical stimulation of baroreceptors are showing promising results.. UR - ...
The authors identified two randomized controlled trials, one observational study with a control group, and nine observational studies without a control group. A total of five different catheters were used across these trials. In controlled studies, there was a reduction in mean systolic (-28.9 mm Hg; 95% confidence interval [CI], -37.2 to -20.6; p < 0.0001) and diastolic (-11.0 mm Hg; 95% CI, -16.4 to -5.7; p < 0.0001) blood pressure (BP) at 6 months compared to medically treated patients. In uncontrolled studies, there was a similar reduction in mean systolic (-25.0 mm Hg; 95% CI, -29.9 to -20.1) and diastolic (-10.0 mm Hg; 95% CI, -12.5 to -7.5) blood pressure at 6 months compared to pre-RDN values. There was no difference in the effect of RDN according to the type of the device used. Reported procedural complications included one renal artery dissection and four femoral pseudoaneurysms.. ...
List of causes of Headache and Vasovagal syncope, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
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Study of US veterans found that patients with resistant hypertension had higher risks of myocardial infarction, stroke, and end-stage renal disease.
MIAMI -- Renal denervation aimed at reducing refractory blood pressure provides some patients with an additional benefit -- a reduction in heart rate.
KNOWN HISTORY: Zoro was brought in as a stray, so we cannot speak to his behavior in his previous home. MEDICAL BEHAVIOR: Growling but allowed handling ENRICHMENT NOTES: 06/04/17 Lying in back of kennel with a low body, ears flattened. He hisses when spoken to and tolerates petting while lowering his body. Turns head and hisses as the bear-claw passes along his back, body very tense. Needs more time to adjust. 06/05/17 Lying in back of kennel with a low body, head resting on ground. He flits his head when I open the kennel door and gives one hard hiss, making eye contact. He hisses and tenses his body as the bear-claw comes forward. He relaxes a bit when I place a treat in front of him - ears come forward and he sniffs and eats the treat in front of me. Hes not read to be touched yet but I spend some time using the clicker and giving him treats so he can associate the sound with something good. He will come to the front to eat treats but will hiss at me when hes finished. Needs more time to ...
Disc denervation is used to treat chronic disc-related or discogenic pain using radiofrequency ablation to destroy affected nerves causing pain.
Facet Denervation is available in Charlottesville VA. Facet Joints are the joints between the vertebrae in your spine that allow flexibility in the back.
Hey, With upgrade that introduced Albatros there came a wire hiss sound in biplanes with wire braced wings. Some people claim to not notice it, to most, its harmless. Unfortunately, I am oversensitive to it and it causes headache, nausea, irritation, problems concentrating etc. I have verified (b...
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Since 2012, several cases of renal stenosis after renal denervation have been reported, demonstrating a wide spectrum of clinical presentation, but presenting recurrent hypertension as most relevant finding (1).. In the previous trials HTN-1 (Symplicity Renal Denervation in Patient With Refractory Hypertension) (2) and EnligHTN-I (Safety and Efficacy of Study of Renal Artery Ablation in Resistant Hypertension Patients) (3), renal artery stenosis had been attributed mainly to pre-existing artery stenosis worsening and not to a de novo procedure-related adverse event. The increasing reports of the last call into question the safety of this procedure and point to this complication as a possible cause of therapy ineffectiveness. ...
Latest urology and nephrology news, research and treatment articles for urologists and nephrologists to stay updated. Clinical reviews on renal and urology treatments.
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The role of the sinoaortic reflexes in the regulation of ventilation during exercise was evaluated in seven awake dogs prepared with chronic tracheostomies and arterial catheters. Each dog ran on a treadmill at several work loads before and after sin
To the extent that the patient remembers it, how do they describe the event?. A prodrome is an early, sometimes subtle set of symptoms that warn of a problem developing. Prodromes are our friend, because although they can be very brief or non-obvious, when present they can help indicate what happened. So, ask! Its the O in OPQRST, and its the E in SAMPLE, so its the beginning and end of our patient history-no excuses!. Vasovagal syncope is one of the most common causes of syncope, involving a transient drop in blood pressure, and vasovagal syncope is usually preceded by a prodrome. If youve never had the experience of standing up too fast and getting briefly faint, heres the gist: you become light-headed, your vision blurs or darkens, you feel weak, you may stumble, and finally you go down. There may also be broad neurological symptoms, such as visual disturbances ("seeing spots"), strange sensations, shaking, and more. (Basically, your brain isnt getting enough oxygen, so odd stuff ...
I first listened to the Eleven Rack on a pair of Sony MDR-7506 headphones, playing my Erisa Custom Strat (hand made in Auroville) with Lindy Fralin single-coils. The Fralins are pretty low-output pickups with outstanding clarity. Used first a Planet Waves circuit-breaker and then a Monster Rock cable.. Having used a Guru Plexi tube head (also hand-made in Auroville) for a while, I naturally gravitated to the Marshall Plexi models first, and was immediately surprised by the Eleven Racks single-focus approach: the controls on this model are exactly the same as on the original amp - with no Master Volume, which is the sound of a Plexi. On any POD, for example, youll have a generic set of drive/bass/mid/treb/presence/vol controls that work on ALL models - NOT the way the original amps are. On the Eleven Rack, if the original amp has just a drive cut and bass control, thats exactly what you get on the model. This, I found, made it much easier to get a good sound from an amp model, fast. Dial ...
Psychiatry healthcare professionals gain a thorough knowledge base of psychiatric disorder information to offer the best patient care. Get our FREE app now.
BACKGROUND: Treatment of hypertension in the elderly people reduces the risk of cardiovascular and cerebrovascular events. Effective treatment often will require the use of two or more antihypertensive agents. Elderly people are at increased risk of
I would ask any potential person to ask many questions before having spermatic cord denervation. Especially regarding stats that make this look like a better treatment then is stated. Almost everyone will likely feel b…
After I posted about the issue on gearslutz, a kind forum member pointed to me that I was not alone with this hiss problem either . Others had seen the same problem using some MXL 990 and 991 microphones on the M-Audio 2626 .The M-audio forum members suspected that it had to do with phantom power on the M-audio 2626. But one of them said their other phantom-powered mikes, AKG C3000B, did not show the hiss. I own these mikes as well, and they did not show the hiss on my 2626 either. My conclusion was that this is an issue with the preamps built-in to the 2626 that only shows with certain microphones, for some reason. This is an issue that many others have seen with multiple microphones, but not at all. It is once again, an issue for which M-Audio does not have a fix. What makes it really unforgivable is the fact this this issue exists between M-Audios own Pulsar II microphones and Profire 2626 preamp . I contacted M-Audio support about this second issue on May 16. I asked them to test their ...
Hey, all, I know it might seem a bit pointless to favorite tracks on Tape Hiss shows, since they arent archived -- but please do so anyhow, if you feel so inspired. My marathon premium this year will feature a lot of tracks that aired on Tape Hiss shows, so knowing what people like will help me decide what to include ...
Unlike a lot of my posts which tend to be somewhat technical, this is actually rather straightforward an approach. For this study we were able to obtain the somatic organs and the associated nerve plexi from a number of patients that had FXTAS during life during autopsy. We sent the tissues to the hospitals central…
My cat is 14 and immediately after hissing he starts to cough/wheeze. I rub his back, but what is going on. He hisses infrequently (thank goodness),
TWEETS from #ACEP17 LLSA readings reviews. 2017 LLSA review with Lovata at #ACEP17 https://t.co/dOTCNOLga5. ACEP clincial policy on aortic dissection for 1st #LLSA #ACEP17. Are there clincial decision rules for low risk pts for aortic dissection? NO #LLSA #ACEP17. Is D Dimer adequate to ID low risk aortic dissection? NO #LLSA #ACEP17. Is CTA equivalent to MRI or TEE for dx of aortic dissection? YES. #LLSA #ACEP17 level B. Can transthoracic echo rule out aortic dissection? NO #LLSA #ACEP17. When we decrease SBP and HR for aortic dissection is morbidity and mortality reduced? Not great evidence level C #LLSA #ACEP17. Angioedema up next #LLSA #ACEP17 rapid firing. Types are Histamine with and without anaphylaxis, ACE inhib and hereditary angioedema #LLSA #ACEP17. Most widely available agent for hereditary angioedema is FFP (not beat but most available) #LLSA #ACEP17. Upper airway angioedema; lower too? Direct visualization to assess. #LLSA #ACEP17. CCB overdose with literature review article. ...
If these tests are normal, you may have a tilt table test. For this test, you lie down on a platform. Your heart rate and blood pressure are measured while you are lying down. The platform is then tilted upright. Your heart rate and blood pressure are measured again. If you have vasovagal syncope, you may faint during the upward tilt. Sometimes medicines that increase heart rate and the force of heart contractions are used to try and provoke a syncopal episode.. There are many causes of syncope. Some causes are not dangerous. In older persons, unexplained syncope can be a sign of a serious infection or a heart attack. Call 911 or seek immediate medical attention to be evaluated, especially if there has been a fall and injury with the syncope. You should not drive yourself to the hospital or emergency department after a syncopal episode for the safety of yourself or other drivers and passengers. Have someone drive you. Your provider may restrict your driving until the cause of the syncope is ...
A total of 38 patients were included in this analysis. The patient characteristics were as follows: median age, 60 years (range, 22 to 72); male/female, 26/12; PS 0/1, 22/16; UICC-TNM stage III/IV, 12/26; primary site head/body-tail, 16/22; biliary intervention yes/no, 10/28; UGT genetic polymorphisms wild type/UGT1A1*6 or *28 heterozygote, 26/12. The median number of cycles administered was 6 (range, 1 to 22). During the first 2 cycles of treatment, FN occurred in 23.6% of the patients. There were no treatment-related deaths. A multivariate logistic regression analysis showed that the pretreatment platelet count ≦15*104 /&mgr;L (OR: 8.07, 95% CI: 1.03 to 63.2, p = 0.047) and heterozygous UGT1A1*6 or *28 (OR: 8.60, 95% CI: 1.36 to 54.2, p = 0.022) were significantly associated with higher risk of FN. ...
Objective A clinical trial (REQUIRE) was started to investigate the use of an ultrasound renal denervation system in the treatment of resistant hypertension (RHT). We analyzed the prevalence of patients who were eligible for inclusion in this cross-sectional study at the time of screening. Methods Nine-hundred ninety-nine consecutive hypertension (HT) patients who were treated in our hospital as outpatients were classified into the following categories: patients treated with at least 3 types of antihypertensive drugs including diuretic agents who were eligible for enrolment in SYMPLICITY HTN-Japan (SH-J) with an office systolic blood pressure (SBP) of ≥160 mmHg, who were ≤80 years of age, and an eGFR of ≥45 mL/min/1 ...
Physician assistants and nurse practitioners use Clinical Advisor for updated medical guidance to diagnose and treat common medical conditions in daily practice.
Methods and apparatus are provided for selective denervation of conduction pathways in the heart for the treatment of dysrhythmias, including one or more ablation or electroporation catheters having electrodes for stimulating, targeting, and ablating fat pad tissue and other cardiac tissue to selectively denervate heart tissue.
Nephrology Now is an editorially independent and free service to help you stay up to date with new developments in Nephrology ...
If you are facing any type of problem on this portal. We are here to help you.. Kindly take the print screen of the issue which you are facing and mail us on the following id :. [email protected], or fill the following form with the required information: ...
Find online guide about Womens Autonomic Nervous System, Visit now for useful articles like What Occurs While Your Lifestyles Adjustments
maropice.com Page 40: Lovely Testicle Anatomy Fresh Veins In the Arm Lovely Vasovagal Syncope New C7 Vertebrae Lovely Human Anatomy Muscle pig testicle anatomy testicular anatomy on ultrasound testicular us anatomy turkey testicle anatomy testicular anatomy on ultrasound - Human Anatomy
We measured glucose metabolism in five dogs before and 3 weeks after cardiac denervation; after this time myocardial norepinephrine is depleted. The discharge by the myocardium, of 14CO2 from infused 14C-D-glucose (U), decreased following denervation (P = 0.05). The ratio of 14CO2 to total CO2 production, which measured the proportion of glucose to total substrate oxidized, also decreased following denervation (P = 0.05). The inhibition of glucose oxidation by denervation was not due to an increase in arterial lactate concentration. There was an associated increase in myocardial content of fructose-6-phosphate in an additional seven dogs (P , 0.01). We postulate that myocardial tissue norepinephrine is one of the controllers of the activity of phosphofructokinase. ...
Author: Sulochana Sakthivel, K.Y.Manjunath. Category: Anatomy. [Download PDF]. Abstract:. Background: Thoracic splanchnicectomy is an important surgical procedure for the management of upper abdominal pain especially in cases of chronic pancreatitis or pancreatic cancer. The pattern of the thoracic splanchnic nerves is highly variable and the outcome of the surgical procedure depends on awareness of the variant anatomy of thoracic splanchnic nerves. This study was undertaken to find out the variations in the formation, course and termination of greater splanchnic nerve in South Indian population.. Materials & Methods: Thirty five human cadavers of either sex (female- 12, male -23), between 45 and 70 years of age, embalmed by conventional method for undergraduate Anatomy classes were bilaterally dissected. Greater splanchnic nerve was studied with regard to its formation, course and termination.. Results: Greater Splanchnic nerve was present in all the specimens. In 41.4%, the highest root of ...
Left vagus nerve aka Nervus vagus sinister in the latin terminology and part of autonomic innervation of the esophagus. Learn more now!
Early trials of renal denervation, the innovative new catheter-based blood pressure lowering technology, have resulted in extremely impressive drops in systolic blood pressure in the range of 30 mm Hg. These results have sparked a great deal of excitement in the hypertension community and stirred the interest of a multitude [...]
Radiofrequency denervation is a treatment for some kinds of lower back and neck pain. It uses an electrical current created by radio waves.
Autonomic nervous system: Autonomic nervous system, in vertebrates, the part of the nervous system that controls and regulates the internal organs without conscious effort.
Autonomic Nervous System Regulation Lessons and Activities GRADES 5 12 Section IV EG HQ, Education Standards, Grades 5 8, Introduction Autonomic Nervous System Regulation TOPIC How
WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms Chills, Diarrhea, Excessive sweating and Fainting and including Fainting (vasovagal syncope), Medication reaction or side-effect and Drug overdose.

Heart rate of the dog following autonomic denervation.Heart rate of the dog following autonomic denervation.

... код для вставки. код для вставки на сайт или в блог. Ширина: (. aвто. ) ... HEART R A T E O F THE DOG FOLLOWING AUTONOMIC D E N E R V A T I O N 1). 12.1. TJONG, R. C . TRUEX, K. R. FRTEI)MAK, 4ND A. K. ... 78 79 CARDIAC: DENERVATION 12ESLr I i TS Thct iritriiisic nerves t o tlie caiiiiit. lit1ai.t 1i:ivc 1 ) ~ ~iiitlicatccl ii hy ... 89 CARDIAC DENERVATION MURPHY,Q. 1942 The influence of the accelerator nerves on the basal heart rate of the dog. Am. J. ...
more infohttps://www.docme.ru/doc/2175312/heart-rate-of-the-dog-following-autonomic-denervation

REMINDER: ORLive Presents: Reality EP: Epicardial Ablation for Atrial Fibrillation -- Minimally Invasive Pulmonary Vein...REMINDER: ORLive Presents: Reality EP: Epicardial Ablation for Atrial Fibrillation -- Minimally Invasive Pulmonary Vein...

Minimally Invasive Pulmonary Vein Isolation and Partial Autonomic Denervation Procedure. Live Webcast February 26, 2008 5:00 PM ... live webcast will feature a panel discussion of a minimally invasive pulmonary vein isolation and partial autonomic denervation ...
more infohttp://www.marketwired.com/press-release/reminder-orlive-presents-reality-ep-epicardial-ablation-atrial-fibrillation-minimally-825400.htm

Vagal Reactions during Cryoballoon-Based Pulmonary Vein Isolation: A Clue for Autonomic Nervous System Modulation?Vagal Reactions during Cryoballoon-Based Pulmonary Vein Isolation: A Clue for Autonomic Nervous System Modulation?

3. Cardiac Autonomic Denervation during Cryoballoon-Based Pulmonary Vein Ablation. The CB technique targets the PVs and ... Y. Zhang, Z. Wang, Y. Zhang et al., "Efficacy of cardiac autonomic denervation for atrial fibrillation: a meta-analysis," ... 2. Cardiac Autonomic Denervation during Radiofrequency Pulmonary Vein Ablation. Ganglionated plexi ablation aiming for ... D. G. Katritsis, E. Pokushalov, A. Romanov et al., "Autonomic denervation added to pulmonary vein isolation for paroxysmal ...
more infohttps://www.hindawi.com/journals/bmri/2016/7286074/

Sudden Cardiac Death | CirculationSudden Cardiac Death | Circulation

Autonomic denervation after myocardial infarction. Extent of cardiac hydroxyephedrine (11C-HED, sympathetic neurotransmitter ... Autonomic Nervous System. Abnormalities of the autonomic nervous system appear to be involved in the genesis of sudden cardiac ... which is taken as a surrogate for autonomic actions at the ventricular level. Autonomic effects at the sinus node and ventricle ... Myocardial hypertrophy, congestive heart failure, and cardiac dilation,31 32 as well as regional autonomic dysfunction,33 34 ...
more infohttp://circ.ahajournals.org/content/98/21/2334.long

Fight Aging! Newsletter, May 23rd 2016 - Fight Aging!Fight Aging! Newsletter, May 23rd 2016 - Fight Aging!

... during autonomic denervation in vivo; and (iii) ex vivo, in the intact isolated SAN tissue (i.e. in which the autonomic neural ... in the absence of autonomic receptor stimulation, drives many of the same cell mechanisms that are modulated by autonomic ... We analyzed BI dynamics in mice of varying ages: (i) in vivo, when the autonomic input to the sinoatrial node is intact; (ii) ... In contrast to the preservation of the average basal BI, the average intrinsic BI, that is, in the absence of autonomic neural ...
more infohttps://www.fightaging.org/archives/2016/05/fight-aging-newsletter-may-23rd-2016/

Impacts of Renal Sympathetic Activation on Atrial Fibrillation: The Potential Role of the Autonomic Cross Talk Between Kidney...Impacts of Renal Sympathetic Activation on Atrial Fibrillation: The Potential Role of the Autonomic Cross Talk Between Kidney...

Recently, RSN denervation has been shown to protect against AF in both animal models and humans. However, the optimal ablation ... Cardiac autonomic nervous system: a tug of war between the big brain and little brain-friends or foes? Heart Rhythm. 2009;6: ... Changes of autonomic neural function by RSS in 4 groups. A, Sinus rate (SR) change induced by superior left ganglionated plexus ... The importance of autonomic nerve disorder in the genesis and maintenance of AF has been well recognized.1 Recently, there has ...
more infohttp://jaha.ahajournals.org/content/6/3/e004716

Familial Dysautonomia
      - Riley Day Syndrome
     Summary Report | CureHunterFamilial Dysautonomia - Riley Day Syndrome Summary Report | CureHunter

Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From ... An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. ... caused by chronic autonomic denervation.". 10/14/1967 - "Evidence for autonomic denervation in familial dysautonomia, the Riley ... Autonomic Denervation 12/01/2010 - "Studies in patients with familial dysautonomia have shown that abnormal cardiac autonomic ...
more infohttp://www.curehunter.com/public/keywordSummaryD004402-Familial-Dysautonomia-Riley-Day-Syndrome.do

Renal Nerve Stimulation-Induced Blood Pressure Changes Predict Ambulatory Blood Pressure Response After Renal...Renal Nerve Stimulation-Induced Blood Pressure Changes Predict Ambulatory Blood Pressure Response After Renal...

Right ventricular infarction causes heterogeneous autonomic denervation of the viable peri-infarct area. Circulation. 1998;97: ... European Network COordinating research on Renal Denervation (ENCOReD). Blood pressure changes after renal denervation at 10 ... Impact of renal denervation on 24-hour ambulatory blood pressure: results from SYMPLICITY HTN-3. J Am Coll Cardiol. 2014;64: ... Renal denervation after Symplicity HTN-3: an update. Curr Hypertens Rep. 2014;16:460. doi: 10.1007/s11906-014-0460-x. ...
more infohttp://hyper.ahajournals.org/content/68/3/707

Glucocorticoid Signaling in the Arcuate Nucleus Modulates Hepatic Insulin Sensitivity | DiabetesGlucocorticoid Signaling in the Arcuate Nucleus Modulates Hepatic Insulin Sensitivity | Diabetes

Effects of thyrotoxicosis and selective hepatic autonomic denervation on hepatic glucose metabolism in rats. Am J Physiol ... HSX, hepatic sympathetic denervation; HPX, hepatic parasympathetic denervation; ShamX, sham denervation. #P , 0.05 vs. basal ... Hepatic sympathetic, parasympathetic, or sham denervation per se had no effects on basal plasma glucose or EGP (Fig. 3A and B ... Differences in surgical denervation protocols and acute versus chronic study design may account for some of the discordance ...
more infohttp://diabetes.diabetesjournals.org/content/61/2/339.full

123)I-Labelled metaiodobenzylguanidine for the evaluation of cardiac sympathetic denervation in early stage amyloidosis.123)I-Labelled metaiodobenzylguanidine for the evaluation of cardiac sympathetic denervation in early stage amyloidosis.

Impact of liver transplantation on cardiac autonomic denervation in familial amyloid polyneuropathyMedicineYear: ... This may imply a differential autonomic neuropathy, which means that cardiac autonomic dysfunction cannot be ruled out in those ... PET in cardiac denervation Various PET analogues of NE are also under investigation [18]. These are even more similar to NE ... Cardiac denervation-heart rate variability relationship There was no difference in SDNN among the three patient groups, nor in ...
more infohttp://www.biomedsearch.com/nih/123I-Labelled-metaiodobenzylguanidine-evaluation-cardiac/22806059.html

Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment |...Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment |...

Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial. . J. ... Autonomic dysfunction. Atrial function is tightly regulated by the autonomic nervous system, which in turn can be an important ... Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation. . Heart Rhythm 2, 624-631 (2005). ... Autonomic trigger patterns and anti-arrhythmic treatment of paroxysmal atrial fibrillation: data from the Euro Heart Survey. . ...
more infohttps://www.nature.com/articles/nrcardio.2015.194?error=cookies_not_supported&code=910f5566-1d4c-4f43-bc30-ebab15cee6af

Imaging the Vesicular Acetylcholine Transporter Using 18F-FEOBV PET in Parkinsons Disease - Full Text View - ClinicalTrials.govImaging the Vesicular Acetylcholine Transporter Using 18F-FEOBV PET in Parkinsons Disease - Full Text View - ClinicalTrials.gov

Density of vesicular acetylcholine transporter will be correlated to symptoms of gastrointestinal autonomic denervation ( ... The aim is to validate 18F-FEOBV PET/CT as a clinical imaging modality to diagnose parasympathetic denervation in PD. ... Patients with Parkinsons disease (PD) often display symptoms, such as constipation, due to denervation of the cholinergic ... Furthermore, findings are correlated to validated clinical tests of the autonomic nervous system. ...
more infohttps://clinicaltrials.gov/ct2/show/NCT03554551?term=molecular+imaging&sfpd_d=30

Natural Hyperhidrosis Cure and Treatment - Diabetes AidNatural Hyperhidrosis Cure and Treatment - Diabetes Aid

Peripheral Autonomic Denervation Last Updated on Sun, 02 Sep 2018 , Type 1 Diabetes ... Peripheral autonomic denervation can have many clinical manifestations and contributes to changes to the skin texture, edema, ... The effects of autonomic stimulation of end-organs such as the heart and sweat glands underlie the typical auto-nomic symptoms ... Evidence cited usually emanate from surgical lesions (77). In diabetic autonomic neuropathy, the sympathetic denervation that ...
more infohttps://www.diabetesaid.com/hyperhidrosis.html

Neuroanatomical correlates of behavioural disorders in dementiaNeuroanatomical correlates of behavioural disorders in dementia

Changes in cerebral morphology consequent to peripheral autonomic denervation. Neuroimage. 2003;18:908-16. [PubMed] ... the SGC has been implicated in autonomic function (Devinsky et al., 1995) and tracking of reward value (Rolls, 2000, 2004). ... and activity in this region has also been associated with fluctuations in basal peripheral autonomic activity (Critchley et al ...
more infohttp://pubmedcentralcanada.ca/pmcc/articles/PMC1820861/?lang=en-ca

Association of Left Atrial Booster-Pump Function with Heart Failure Symptoms in Patients with Severe Aortic Stenosis and...Association of Left Atrial Booster-Pump Function with Heart Failure Symptoms in Patients with Severe Aortic Stenosis and...

19880076 - Heart rate, autonomic markers, and cardiac mortality.. 10665906 - Cardiac autonomic denervation in congestive heart ... 11872106 - The short-term effects of myofascial trigger point massage therapy on cardiac autonomic.... 16199056 - Impaired ...
more infohttp://www.biomedsearch.com/nih/Association-Left-Atrial-Booster-Pump/25230926.html

Plus itPlus it

Cahill M, Eustace P, de Jesus V: Pupillary autonomic denervation with increasing duration of diabetes mellitus. Br J Ophthalmol ... 22), who in 2001 reported that pupillary autonomic denervation increases with increasing duration of diabetes mellitus. ...
more infohttp://care.diabetesjournals.org/content/28/10/2448

CiNii Articles - 早川 直和CiNii Articles - 早川 直和

Effect of upper abdominal autonomic denervation on glucagon secretion after intraduodenal glucose administration in dogs. (1988 ...
more infohttps://ci.nii.ac.jp/author?q=%E6%97%A9%E5%B7%9D+%E7%9B%B4%E5%92%8C

British Society of Gastroenterology guidelines for the management of the irritable bowel syndrome | GutBritish Society of Gastroenterology guidelines for the management of the irritable bowel syndrome | Gut

1990) Idiopathic autonomic denervation in eight patients presenting with functional gastrointestinal disease. A causal ... 5.5 ABNORMAL AUTONOMIC REACTIVITY IN IBS. Altered autonomic reactivity has been noted in IBS, with decreased vagal tone ... 1999) Evidence for autonomic nervous system imbalance in women with irritable bowel syndrome. Dig Dis Sci 43:2093-2098. ... The potential role of autonomic dysfunction in IBS is made more plausible by the report from the Mayo Clinic of eight patients ...
more infohttp://gut.bmj.com/content/47/suppl_2/ii1.full

Professor John CammProfessor John Camm

Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomised clinical trial. J Am ...
more infohttps://sgul.ac.uk/research-profiles-a-z/john-camm

Familial amyloid neuropathy - WikipediaFamilial amyloid neuropathy - Wikipedia

July 2006). "Impact of liver transplantation on cardiac autonomic denervation in familial amyloid polyneuropathy". Medicine ( ... The aggregation of one precursor protein leads to peripheral neuropathy and/or autonomic nervous system dysfunction. These ... are a rare group of autosomal dominant diseases wherein the autonomic nervous system and/or other nerves are compromised by ... wild type and different mutant subunits against amyloidogenesis halting the progression of peripheral neuropathy and autonomic ...
more infohttps://en.wikipedia.org/wiki/Familial_amyloid_neuropathy

Plus itPlus it

2007) Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease. J ...
more infohttps://www.jneurosci.org/content/31/10/3610

Evaluation of Novel Dry Eye Model: Preganglionic Parasympathetic Denervation in Rabbit | IOVS | ARVO JournalsEvaluation of Novel Dry Eye Model: Preganglionic Parasympathetic Denervation in Rabbit | IOVS | ARVO Journals

Changes in nerve terminals and acini of the lacrimal gland and changes in secretion induced by autonomic denervation. Z ... Sensory denervation of the rabbit cornea affects epithelial properties. Exp Neurol. 1980;69(1)196-201. [CrossRef] [PubMed] ... Ocular autonomic nerve function in Lambert-Eaton myasthenic syndrome. Eye. 1990;4(pt 3)473-481. [CrossRef] [PubMed] ... The distribution of autonomic post-ganglionic nerve fibres to the lacrimal gland in monkeys. J Anat. 1971;109(pt 2)229-242. [ ...
more infohttps://iovs.arvojournals.org/article.aspx?articleid=2183081

Sympathectomy - a stress response attenuation: no chance for nerve regeneration as early as 10 days after clippingSympathectomy - a stress response attenuation: no chance for nerve regeneration as early as 10 days after clipping

Absent peripheral autonomic arousal, in patients with autonomic denervation, was associated with decreased conditioning-related ... decreased conditioning-related activity in insula and amygdala after autonomic denervation. The degree to which perceptual ... We used functional magnetic neuroimaging (fMRI) to study healthy subjects and patients with peripheral autonomic denervation to ... Other causes of autonomic dysfunction without neurological signs include medications, acute autonomic failure, endocrine ...
more infohttp://sympathectomy.blogspot.com/2012/08/no-chance-for-nerve-regeneration-as.html

sympathectomy - controversy: 10/28/12 - 11/4/12sympathectomy - controversy: 10/28/12 - 11/4/12

Absent peripheral autonomic arousal, in patients with autonomic denervation, was associated with decreased conditioning-related ... decreased conditioning-related activity in insula and amygdala after autonomic denervation. The degree to which perceptual ... We used functional magnetic neuroimaging (fMRI) to study healthy subjects and patients with peripheral autonomic denervation to ... Thermal image showing autonomic dysfunction following ETS surgery. major effects on local blood flow and temperature are elicited ...
more infohttp://sympathectomy-controversy.blogspot.com/2012_10_28_archive.html
  • 58 ] recently reported an association between dermal alpha-synuclein deposition and reduced autonomic innervation, using an alpha-synuclein-antibody that is not specific to the phosphorylated form. (springer.com)
  • H/M ratio) was verified by clinical diagnosis of PD, MSA, and ET based on a two-stage clinical assessment: comprehensive baseline (including autonomic testing and additional neuroimaging) and confirmatory clinical follow-up. (frontiersin.org)
  • Heart rate of the dog following autonomic denervation. (docme.ru)
  • Parameters that evaluate global cardiac autonomic activity (total power, SD of normal R-R intervals, SD of average normal R-R intervals) and vagal activity (rhythm corresponding to percentage of normal R-R intervals with cycle greater than 50 ms relative to previous interval, square root of mean squared differences of successive normal R-R intervals, high-frequency power, high-frequency power in normalized units) were statistically significantly increased after sympathectomy. (blogspot.com)