Agents affecting the function of, or mimicking the actions of, the autonomic nervous system and thereby having an effect on such processes as respiration, circulation, digestion, body temperature regulation, certain endocrine gland secretions, etc.
A naturally occurring dipeptide neuropeptide found in muscles.
An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
Any substances taken in by the body that provide nourishment.
The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
EXOPEPTIDASES that specifically act on dipeptides. EC 3.4.13.
The branch of applied psychology concerned with psychological aspects of selection, assignment, training, morale, etc., of Armed Forces personnel.
Refusal to admit the truth or reality of a situation or experience.
Based on known statistical data, the number of years which any person of a given age may reasonably expected to live.
A system containing any combination of computers, computer terminals, printers, audio or visual display devices, or telephones interconnected by telecommunications equipment or cables: used to transmit or receive information. (Random House Unabridged Dictionary, 2d ed)
A type of nuclear polyploidization in which multiple cycles of DNA REPLICATION occur in the absence of CELL DIVISION and result in a POLYPLOID CELL.
An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.
A plant genus of the family BRASSICACEAE. The common name of white mustard sometimes refers to other plants (MUSTARD PLANT).
A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes.
Biphasic dose responses of cells or organisms (including microorganisms) to an exogenous or intrinsic factor, in which the factor induces stimulatory or beneficial effects at low doses and inhibitory or adverse effects at high doses.
A plant genus, in the family AMARANTHACEAE, best known as a source of high-protein grain crops and of Red Dye No. 2 (AMARANTH DYE). Tumbleweed sometimes refers to Amaranthus but more often refers to SALSOLA.
(11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.
(9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (PGF(2 alpha)); (5Z,9 alpha,11 alpha,13E,15S,17Z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (PGF(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring PGF have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics.
Procedure in which arterial blood pressure is intentionally reduced in order to control blood loss during surgery. This procedure is performed either pharmacologically or by pre-surgical removal of blood.
A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)
Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)
A parathyroid hormone receptor subtype found in the BRAIN and the PANCREAS. It is a G-protein-coupled receptor with a ligand specificity that varies between homologs from different species.
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
Preparation for electron microscopy of minute replicas of exposed surfaces of the cell which have been ruptured in the frozen state. The specimen is frozen, then cleaved under high vacuum at the same temperature. The exposed surface is shadowed with carbon and platinum and coated with carbon to obtain a carbon replica.
Middle portion of the hypothalamus containing the arcuate, dorsomedial, ventromedial nuclei, the TUBER CINEREUM and the PITUITARY GLAND.
The science and technology dealing with the procurement, breeding, care, health, and selection of animals used in biomedical research and testing.
A scanning microscope-based, cytofluorimetry technique for making fluorescence measurements and topographic analysis on individual cells. Lasers are used to excite fluorochromes in labeled cellular specimens. Fluorescence is detected in multiple discrete wavelengths and the locational data is processed to quantitatively assess APOPTOSIS; PLOIDIES; cell proliferation; GENE EXPRESSION; PROTEIN TRANSPORT; and other cellular processes.
The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.
A thiosemicarbazone that is used in association with other antimycobacterial agents in the initial and continuation phases of antituberculosis regimens. Thiacetazone containing regimens are less effective than the short-course regimen recommended by the International Union Against Tuberculosis and are used in some developing countries to reduce drug costs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p217)
Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.
Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).
A specialized agency of the United Nations designed as a coordinating authority on international health work; its aim is to promote the attainment of the highest possible level of health by all peoples.
A cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.
Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc.
A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants.
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than CURARE but has less effect on the circulatory system and on histamine release.
Monoquaternary homolog of PANCURONIUM. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.
A large plant family in the order Apiales, also known as Umbelliferae. Most are aromatic herbs with alternate, feather-divided leaves that are sheathed at the base. The flowers often form a conspicuous flat-topped umbel. Each small individual flower is usually bisexual, with five sepals, five petals, and an enlarged disk at the base of the style. The fruits are ridged and are composed of two parts that split open at maturity.
A plant genus of the family ACORACEAE, order Arales, subclass Arecidae most notable for Acorus calamus L. root which contains asarone and has been used in TRADITIONAL MEDICINE.
A plant genus in the family MYRTACEAE, order Myrtales, subclass Rosidae. It is best known for allspice from the dried berry of Pimenta diocia.
A plant species in the PIPERACEAE plant family. It is a common spice on foods and is used medicinally to increase gastrointestinal assimilation of other supplements and drugs. Piperine is a key component. Black pepper is picked unripe and heaped for a few days to ferment. White Pepper is the ripe fruit dehulled by maceration in water.
The myrtle plant family of the order Myrtales. It includes several aromatic medicinal plants such as EUCALYPTUS.
A plant family of the order Arales, subclass Arecidae, class Liliopsida (monocot).
A common spice from fruit of PIPER NIGRUM. Black pepper is picked unripe and heaped for a few days to ferment. White Pepper is the ripe fruit dehulled by maceration in water. Piperine is a key component used medicinally to increase gastrointestinal assimilation of other supplements and drugs.

Effect of physiological mechanical perturbations on intact human myocardial repolarization. (1/69)

OBJECTIVE: The objective of this study was to investigate the relationship between acute decreases in right ventricular volume during Valsalva strain (with resultant changes in autonomic neural tone) and measures of local endocardial repolarization time independent of heart rate and autonomic neural tone. METHODS: Patients implanted with a stimulus to T wave (Stim-T) sensing pacemaker specially adapted to output a validate measure of beat to beat local repolarization (n = 9) performed Valsalva manoeuvers (40 mmHg for 15 s) while paced at a cycle length of 500 ms. Stim-T intervals were measured before and after autonomic blockade (Block: 0.03 mg/kg i.v. atropine +/- 0.15 mg/kg propranolol). Right ventricular end diastolic volume was estimated by simultaneous 2D-echocardiography. RESULTS: Without autonomic blockade, compared to baseline, repolarization significantly prolonged during Valsalva strain (1.1 +/- 0.7%) and shortened during release (-1.4 +/- 1.0%). After block, strain related repolarization prolongation was also observed (1.0 +/- 0.6%), with significantly less release related repolarization shortening (-0.8 +/- 0.8%) compared to pre-block (P < 0.05). Right ventricular end diastolic volume decreased during strain by 11 +/- 10 and 9 +/- 16% from baseline, pre- and post-block respectively (P < 0.05). CONCLUSION: In a chronically instrumented human model, an acute physiologic volume reduction modestly prolongs right ventricular repolarization independent of changes in rate or autonomic tone.  (+info)

Human ejaculatory duct: parameters of smooth muscle motor activity and modulatory role of autonomic drugs. (2/69)

The contractile behaviour and effects of several autonomic drugs on the motor activity of human isolated ejaculatory ducts were investigated. Ejaculatory ducts exhibited spontaneous contractions characterised by an amplitude of 2.35 +/- 0.28 mN, a duration of 62. 9 +/- 3.72 s and a frequency of 0.64 +/- 0.014 waves min-1. Acetylcholine (10-5-10-4 m) induced a slight increase in basal tone and in the frequency of the contraction waves. These effects were suppressed by atropine (10-4 m). Noradrenaline (norepinephrine) increased the basal tone and frequency of spontaneous contractions in a dose-dependent manner. These responses were competitively inhibited by HEAT, a selective a1-adrenoceptor antagonist. These preliminary functional findings, indicating the presence of spontaneous motor activity of human ejaculatory ducts and its possible control by adrenergic agonists, suggests a physiological role for human ejaculatory duct in the propulsion of semen from the seminal vesicle towards the urethra.  (+info)

Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. (3/69)

Flow-mediated dilatation (FMD) of conduit arteries is dependent on an intact endothelium, although the mechanisms are not fully understood. Using high-resolution ultrasound, we examined the role of endothelial mediators in radial artery dilatation in response to transient (short period of reactive hyperemia) and sustained (prolonged period of reactive hyperemia, hand warming, or an incremental infusion of acetylcholine into the distal radial artery) hyperemia. After short episodes of reactive hyperemia, FMD was abolished by local infusion of the nitric oxide synthesis inhibitor N:(G)monomethyl-L-arginine (5.3+/-1.2% versus 0.7+/-0.7%, P:<0.001). In contrast, basal vessel diameter and dilatation after prolonged episodes of reactive hyperemia, hand warming, and distal infusion of acetylcholine were not attenuated by nitric oxide synthesis inhibition. Inhibition of cyclooxygenase or local autonomic nervous system blockade also had no effect on FMD. Patients with hypercholesterolemia exhibited reduced FMD in response to transient hyperemia, but the response to sustained hyperemia was normal. These data suggest heterogeneity of endothelial responses to blood flow that are dependent on the characteristics of the flow stimulus. Dilatation after brief episodes of hyperemia is mediated by release of nitric oxide, whereas dilatation during sustained hyperemia is unaffected by NO synthesis inhibition. Hypercholesterolemia seems to differentially affect these pathways with impairment of the nitric oxide-dependent pathway and preservation of non nitric oxide-mediated dilatation to sustained flow stimuli.  (+info)

Inhibition of salivary secretion by lipopolysaccharide: possible role of prostaglandins. (4/69)

Inducible (calcium-independent) nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) are important in the regulation of the function of different organs during infection. A single dose of lipopolysaccharide (LPS; 5 mg/kg ip) within 6 h increased NOS activity (20%) and prostaglandin E (PGE) content (100%) in submandibular glands (SMG) and blocked stimulated salivary secretion in adult male rats. The administration of an iNOS synthesis inhibitor, aminoguanidine (AG), with LPS decreased NOS activity and PGE content. Furthermore, the administration of meloxicam (MLX), an inhibitor of COX-2, blocked the increase in PGE and the production of NO. The incubation of slices of SMG in the presence of 3-morpholinosydnonimine, a donor of NO, increased the release of PGE highly significantly. The incubation of SMG in the presence of a PGE(1) analog (alprostadil) increased the production of NO. These results indicate that LPS activates NOS, leading to NO release, which activates COX, generating PGEs that act back to further activate NOS, causing further generation of PGEs by activation of COX. Because the alprostadil administration inhibited stimulated salivation, LPS-induced inhibition of salivation appears to be caused by increased PGE production. Diminished salivary secretion produces poor oral health; thus the use of COX-2 inhibitors to counteract the effects of inhibited salivation should be considered.  (+info)

Effects of autonomic blockers on linear and nonlinear indexes of blood pressure and heart rate in SHR. (5/69)

Recent results in normotensive Wistar-Kyoto (WKY) rats show that nonlinear method may be more specific to quantify sympathetic and parasympathetic activities than the low (LF) and high frequencies (HF) spectral powers of blood pressure (BP) and R-R interval (RR). The present study extends this conclusion to spontaneously hypertensive rats (SHR). Blood pressure was recorded for 30 min before and after intravenous injection of saline, hexamethonium, atropine, atenolol, or prazosin. Mean level, standard deviation (SD), spectral LF and HF components, and three nonlinear indexes (percentage of recurrence, percentage of determinism, and length index of the recurrence plot method) were used to analyze the BP and RR signals. In conscious SHR, sympathetic but not parasympathetic blockade reduced BP level and LF-BP, and increased nonlinear indexes of BP. RR increased after beta-sympathetic and ganglionic blockade, decreased after parasympathetic blockade, and remained unchanged after alpha(1)-sympathetic blockade. SD-RR decreased after ganglionic and alpha(1) blockade, whereas HF-RR increased after beta-sympathetic blockade. The effects on nonlinear indexes of RR are clear and consistent: only alpha(1)-blockade increased the indexes. Our nonlinear indexes may be useful to investigate cardiovascular functions in normotension and hypertension.  (+info)

Innervation both of peri-orbital structures and of the heart by the cervical sympathetic nerves in mouse, rat, guinea-pig, rabbit and cat. (6/69)

1 In anaesthetized rats electrical stimulation of the intact cervical sympathetic nerve produced frequency-dependent lower eyelid contractions and tachycardia. 2 The tachycardia was caused by excitation of efferent fibres since it was equally evident in the pithed rat preparation, and the right nerve was more effective than the left. By contrast, no differences were seen between the responses to right and left vagal stimulation in either rats or rabbits. 3 Guanethidine inhibited both cardiac and eyelid responses, propranolol only the former and phentolamine only the latter, therby revealing the adrenergic nature of the nerves. Hexamethonium caused partial inhibition and the block was intensified by atropine. 4 The inferior eyelid of mice, guinea-pigs and rabbits as well as the nictitating membrane of rabbits and cats were contracted by cervical sympathetic nerve stimulation. In these species too, tachycardia occurred; this was more pronounced with the right than the left sympathetic nerve. The order of cardiac responsiveness was mouse greater than rat greater than guinea-pig greater than rabbit greater than cat. 5 In guinea-pigs histamine-induced bronchoconstriction was reduced by cervical sympathetic nerve stimulation. 6 That discrete cardiac pathways exist in the cervical sympathetic nerves is suggested by the reproducibility of the effects within any one species. The accessibility of the nerves greatly simplifies the examination of drugs in vivo on two different structures innervated by the sympathetic nervous system.  (+info)

The autonomic nervous system and the bladder during spinal shock--an experimental study. (7/69)

During experimental spinal shock, the urethral muscle responded to drugs earlier than the detrusor muscle. Stimulation with parasympathomimetic drugs caused some rise in intravesical pressure, but an unexpected and much greater rise of intraurethral pressure. Bladder evacuation was achieved with the Crede manoeuvre during spinal shock with the combined effect of alpha adrenergic blockade and beta adrenergic stimulation.  (+info)

Electrophysiology and arrhythmogenic activity of single cardiomyocytes from canine superior vena cava. (8/69)

BACKGROUND: The superior vena cava (SVC) has been proved to be a focal point in the initiation of paroxysmal atrial fibrillation. The autonomic nervous system plays an important role in the genesis of atrial fibrillation. However, the arrhythmogenic potentials of SVC and its responses to autonomic agents are not clear. The purpose of this study was to isolate single SVC cardiomyocytes and to investigate their electrophysiological characteristics, as well as the direct effects of autonomic agents. METHODS AND RESULTS: Canine SVC cardiomyocytes were isolated by perfusion with digestive enzymes. The action potentials and ionic currents were investigated in single SVC cardiomyocytes using the whole-cell clamp technique. Dissociation of the SVC yielded rod-shaped single cardiomyocytes with (n=74, 51%) or without (n=71, 49%) pacemaker activities. There were similar densities of inward Ca2+, delayed rectifier K+, transient inward, inward rectifier K+, and pacemaker currents between SVC cardiomyocytes with and without pacemaker activity. SVC cardiomyocytes with pacemaker activity have, however, greater transient outward currents than those without pacemaker activity. In SVC cardiomyocytes, acetylcholine (5.5 micromol/L) abolished the spontaneous activities, but isoproterenol (10 nmol/L), atropine (10 micromol/L), and phenylephrine (10 micromol/L) accelerated the spontaneous activity and induced the occurrences of early or delayed afterdepolarizations. CONCLUSIONS: These findings suggest that SVC cardiomyocytes have distinct action potentials and ionic current profiles that may be responsible for the arrhythmogenic activity of the SVC.  (+info)

In the near future, the U.S. DoD will activate a newly created Global Information Grid (GIG) providing an agile, robust, interoperable and collaborative communication network. This GIG is viewed as the single most important contributor to combat power and protection [1]. The GIG can be characterized as a globally interconnected, end-to-end set of disparate information and processing capabilities available on-demand to warfighters, policymakers and support personnel. Management of the GIG resources and operation will be, of necessity, intrinsic to the architecture and transparent to the user. The development an architecture that is secure against malicious exploitation, data or service denial and data corruption is a principal focus. Introduction of mobile, ad-hoc network elements having intermittent network connectivity and limited life exacerbates this problem. In this paper we explore the GIG and present an innovative application of Autonomic Agent technology currently in development that has ...
Immersed, isolated turtle ventricles were allowed to beat when filling only by suction. Obstruction of ejection at various volumes showed an inverse relationship between residual volume and volume aspirated. Diastolic aspiration occurred even with residual volumes of at least 0.55 ml. Ventricles, filling by suction only, maintained continuous output of up to 3 ml./min. working against pressures of 16 to 22 cm. H2O. In these circumstances ejection was diminished or abolished by acetylcholine and usually increased by epinephrine. This work amplifies and further quantitates recent work showing ventricular diastolic suction in a variety of species.. ...
TY - JOUR. T1 - Oita International Electrocardiology Symposium 2000 Electrophysiology and Management of Lethal Arrhythmias in the New Millennium: From Genes to Bedside. AU - Chen, Yi-Jen. AU - Chen, Yao-Chang. AU - Chen, Shih-Ann. AU - Chan, Paul. AU - Lin, Cheng-I. PY - 2000. Y1 - 2000. N2 - Recent clinical studies show that pulmonary veins (PVs) are important foci of atrial tachyarrhythmias. Autonomic nervous system was known to play a role in the genesis of atrial tachyarrhythmias. The present experiments aimed to investigate the actions of autonomic agents in dog PVs and to explore the arrhythmogenic activity in these tissues. Transmembrane action potentials were recorded with the conventional microelectrode techniques and tension was detected by a transducer. In PV driven electrically, isoproterenol (Isop, 1μM) increased while ACh (1-10μM) depressed twitch force but elevated resting tension. In PV active spontaneously, Isop increased the automatic rate and induced high frequency ...
View Notes - ch%2013%20drugs2 from PHPR 202 at Purdue. PHPR 202 Chapter 13 Autonomic nervous system Koh-Knox January 28, 2011 Learning objectives Describe the four classifications of autonomic drugs
The following is an abbreviated curriculum outline for CTBS (and is subject to change in response to curricular changs at the SOM):. Cardiovascular Physiology: anatomy; cardiac muscle physiology and mechanics; cardiac cycle; ventricular function; cardiac electrophysiology; regulation of cardiac output, vascular physiology.. Physiology of the Autonomic Nervous System: anatomy; neurotransmitters and receptors; autonomic control of cardiovascular function; mechanism of action and physiologic effects of major autonomic drugs. Immunology: cells and organs of the immune system; innate immunity and inflammation; antigen presentation to lymphocytes; molecular basis of immunologic diversity; B-cell and T-cell activation and clonal expansion; antibody- and cell-mediated immune responses. Molecular Biology: DNA structure and synthesis; mutations and DNA repair; molecular genetics techniques; RNA synthesis and processing; protein synthesis and localization; regulation of gene expression.. Anatomy and ...
Additional supportive treatment must be given, which could include light anaesthesia ordeep sedation and fluid therapy until the dog has eliminated the poison. References1. Aaron C K, Howland M A1994 Insecticides: Organophosphates and carbamates. In Goldfranks Toxicologic Emergencies 5th Edition Goldfrank L R, Florenbaum N E,Lewin N A, Weisman R S Howland M A, Hoffman R S (ed) Appleton & Lange,Norwalk 1105 - 1114 2. Adams H R 1988 Cholinergic pharmacology. Autonomic drugs. In Veterinary Pharmacology and Therapeutics Booth N H, McDonald L E (ed) Iowa StateUniversity Press, Iowa 117 - 123 3. Barret D S, Oehme F W, Kruckenberg S M 1985 A review of organophosphorus ester-induced delayed neurotoxicity. Veterinary and Human Toxicology 27(1): 22 -37 4. Beasley V R, Dorman D C 1990 Management of toxicoses. The Veterinary Clinics of North America: Small Animal Practice 20(2): 307 - 337 5. Blakley B R, Yole M J 2002 Species differences in normal brain cholinesterase activities of animals and birds. ...
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The defining characteristics of the specialty of veterinary clinical pharmacology reside in an advanced knowledge of the many complex factors that constitute rational drug therapy in animal patients.. Graduate work in the pharmacology concentration area of the Comparative Biomedical Sciences (CBS) degree includes research at the molecular and cellular level in pharmacology, pharmacokinetics, drug interactions, drug residues and metabolites, anesthetics and autonomic drugs, pulmonary biology, oncology, ophthalmology, gastroenterology, reproductive endocrinology, and lipid-, peptide-, and oxygen-derived mediators of inflammation. Research approaches employ a wide variety of molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell culture and whole organisms. Students selecting pharmacology will focus on one or more of these areas.. A highly individualized curriculum of study is designed to meet the needs and interests of the student while satisfying selected requirements ...
Spanish jasmine, or Jasminum grandiflorum, is one of the most fragrant of the jasmine plants. Primrose jasmine, or Jasminum mesnyi, is another very fragrant plant in the jasmine family. The star...
Senecioylcholine (β,β-dimethylacrylylcholine, SCh) was synthesized from choline bromide and senecioyl chloride.. Senecioylcholine was found to be a ganglion stimulant. A number of its actions are described: 1. SCh produced a pressor response in the absence of atropine. This effect was partially blocked by adrenalectomy and almost completely abolished by ganglionic blockade. 2. The pressor response to SCh was reversed by adrenergic blockade. 3. SCh produced a contraction of the nictitating membrane. This action was antagonized by ganglionic blockade. 4. SCh produced contractions of the isolated frog rectus abdominis.. The results are discussed in terms of known structure-activity relationships.. ...
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Another twiner or scrambler for the warmer zones (8 -10), Jasminum x stephanense is a hybrid of Bee s jasmine & Poet s jasmine (to bee or not to bee. . .) with fragrant, light pink flowers throughout summer. Like its parents, it is a vigorous plant where happy and can take up a lot of room. In our case we have it confined to a large display pot which we can scoot into protection during the coldest nights of winter. That also allows us to restrain its enthusiastic growing. Deciduous.
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However, last year the family, was hit by a new blow - Jasmines kidneys had begun to fail. It appeared they had been affected by the drugs Jasmine was taking to prevent her body rejecting her fathers liver.. The prospect of having to wait months, or possibly years, for a suitable organ to be donated led her husband to put himself forward again as a candidate to donate an organ.. But after tests, doctors told him that his kidneys were not suitable. His wife then stepped forward and was accepted as a potential donor.. Jasmine was able to return to North Farnborough Infant School in January.. The only sign of her illness now is a feeding tube through her nose, which her parents hope can be removed shortly.. Doctors treating her say they have never come across a case of a child receiving living organ donations from both parents.. The NHS Blood and Transplant agency said it was very, very rare for anyone to receive transplants from their mother and father. The couple said Jasmines treatment ...
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Jasmine Hill Garden was a labor of love created by Mary and Ben Fitzpatrick. They moved into a modest 1830 era cottage in the early 1930s and it was there this wonderful garden was concieved and brought to life. The Fitzpatricks made over twenty trips to Greece to purchase the art objects used in the garden. This beautiful creation grew to twenty acres and is a true treasure to behold. Ive lived here for eighteen years, less than twenty minutes away and I cant believe it took me this long to make my first trip ...
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I had intended to review some of the chocolates from the British chocolatier Artisan du Chocolat, as I was in London recently and had previously enjoyed (and written about) them after a visit in 2007. Some businesses in high-end food succeed in respecting customers, others choose to be rigid and deliberately unhelpful. Artisan du Chocolat seems on the face of it to fall into a more positive category, but on this visit I was disappointed.. Unable to make it to their Chelsea shop, I visited the outlet in Selfridges department store. Artisan du Chocolat staff are refreshingly generous with samples when a customer is exploring what to purchase (the range is large and the flavours are at times very interesting). My first sample was, I believe, a jasmine tea chocolate. Alas I found the flavour to be on the barely-present side of fleeting and I mentioned that the flavour was too mild for me. I was disappointed to receive in reply a vacuous We only use natural ingredients, so the flavours are often ...
|p|So Im new to the whole testing thing (Ive been one of those people who has said I should write unit tests... but never ended up ever doing it :-p). Im now writing unit tests for this project. Im using testacular + Jasmine, with browserify to compile things. I was having no problems until I started trying to do a lot angular-injection-stuff.|/p| |p|Right now Im simply trying to do a test of ng-model to get my head around all of it.|/p| |p|I have a testacular.conf file which includes everything necessary:|/p| |pre||code|files = [ ../lib/jquery.js, ../lib/angular.js, ./lib/jasmine.js, ./lib/angular-mocks.js, JASMINE_ADAPTER, ./tests.js //compiled by browserify ]; |/code||/pre| |p|I have my controller defined (MainCtrl.coffee)|/p| |pre||code|MainCtrl = ($scope, $rootScope) -> $scope.hello = initial module.exports = (angularModule) -> angularModule.controller MainCtrl, [$scope, $rootScope, MainCtrl] return MainCtrl |/code||/pre|
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we got our waterproof mattress pad at TJMaxx - its not only waterproof, it has a thick layer over the waterproof layer (not all of them do) Any store with a baby department will have them of course, and stores with well stocked junior/toddler bedding sections have them too. They get really hot though, because no air gets through, so we have a regular one on top of the waterproof one and its noticeably more comfortable that way. Some are also very noisy, so thats something to take into account. Ruby is spay incontinent, and she sleeps in bed with us, so this is old had for me ...
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Interestingly, Jasmine was never the least afraid of me, even at the beginning when I didnt know better and used corrections a lot, because thats what I was told I needed to do. I was trying to intimidate her and she just looked at me, aha, youre very scary, mom, but I know you dont mean it, so why dont you just cut it out.. Delete ...
Baby Roshan is one week old today and what a week its been it was hard being late, then a long labor and c section, but the body is amazing at healing itself and I am getting back to normal slowly. Its been such a blessing having Mum and Dad here to help I dont think I could have done it without them especially grateful to Mum for caring for Jasmine while I was in labor then in the hospital. Little Roshan is amazing feeding and growing well, content and gorgeous. Breast feeding was hard for a few days but to all new mums stick with it, gets better ...
His popularity with women has waned in recent months after he split with wife of 21 years Cassandra Thorburn only to get together with the much younger Jasmine Yarbrough.
Jasmine Whitney says they were peacefully protesting when one protester, Kwame Rose, was allegedly arrested for asking a question.
Baseball will eventually be back at Re/Max Field, and when it returns, the downtown ballpark will feature a new team and a new league.
1599-. ISBN 978-0-412-46630-4. Milne GW (1 January 2001). Ashgate Handbook of Autonomic Nervous System Agents. Wiley. ISBN 978- ... Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. ...
ISBN 0-7817-3639-0. Hibbs, Ryan E.; Zambon, Alexander C. (2011). "Agents Acting at the Neuromuscular Junction and Autonomic ... Fleming, David G.; Hall, James L. (1959). "Autonomic Innervation of the Ciliary Body: A Modified Theory of Accommodation". ...
Hughes R, Chapple DJ (1976). "Effects of Non-Depolarizing Neuromuscular Blocking Agents on Peripheral Autonomic Mechanisms in ... Alcuronium chloride is a neuromuscular blocking (NMB) agent, alternatively referred to as a skeletal muscle relaxant. It is a ... a very long acting neuromuscular blocking agent For a formal definition of the durations of actions associated with NMB agents ... and at one time marketed as the proprietary agent called Alloferin). Inclusion of the allylic functions presented an enhanced ...
Application domains have included robot soccer, autonomous bidding agents, autonomous vehicles, autonomic computing, and social ... He has also developed agents that have won auction trading agents competitions (2000, 2001, 2003, 2005, 2006, 2008, 2009, 2010 ... The RoboCup Synthetic Agent Challenge 97. In Proceedings of the Fifteenth International Joint Conference on Artificial ... The RoboCup Physical Agent Challenge: Phase-I. Applied Artificial Intelligence, 12:251-263, 1998". "Publications by Peter Stone ...
... peripheral nervous system agents MeSH D27.505.696.663.050 - autonomic agents MeSH D27.505.696.663.050.030 - antiemetics MeSH ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Agents used include paralytic agents such as botox used on extraocular muscles, topical autonomic nervous system agents to ... Some agents (e.g., botulinum toxin) can be injected at the insertional end of a muscle under visual guidance, using special ... and for some agents, under light general anesthesia. In the former case, it is possible to bring the injection needle to an ... alter the refractive index in the eyes, and agents that act in the central nervous system to correct amblyopia. Strabismus is a ...
Some autonomic systems involve mobile agents interacting via loosely coupled communication mechanisms. Autonomy-oriented ... Autonomic Computing by Richard Murch published by IBM Press Autonomic Computing articles and tutorials Practical Autonomic ... An autonomic computing framework is composed of autonomic components (AC) interacting with each other. An AC can be modeled in ... The Autonomic Computing Initiative (ACI) aims at providing the foundation for autonomic systems. It is inspired by the ...
They may be caused by motor neurone diseases, sensory neuronopathies, toxins, or autonomic dysfunction. Neurotoxins such as ... chemotherapy agents may cause neuronopathies. Among the signs/symptoms of polyneuropathy, which can be divided (into sensory ... hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic ...
... and other vasopressor agents. However, often a patient with pure autonomic failure can mitigate his or her symptoms with far ... indicate possible autoimmune autonomic ganglionopathy or multiple system atrophy. The pathology of pure autonomic failure is ... Pure autonomic failure". Handbook of Clinical Neurology. Autonomic Nervous System. Elsevier. 117: 243-257. doi:10.1016/b978-0- ... now grouped as primary autonomic disorders (also called primary dysautonomia), including Pure Autonomic Failure, Multiple ...
... the autonomic nervous system 972 Poisoning by agents primarily affecting the cardiovascular system 973 Poisoning by agents ... 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system 976 Poisoning by agents ... 962 Poisoning by hormones and synthetic substitutes 963 Poisoning by primarily systemic agents 964 Poisoning by agents ... by psychostimulants 969.8 Poisoning by other specified psychotropic agents 969.9 Poisoning by unspecified psychotropic agent ...
Whitestein Series in Software Agent Technologies and Autonomic Computing, published by Springer Science+Business Media Group ... Typically multi-agent systems research refers to software agents. However, the agents in a multi-agent system could equally ... A multi-agent system may contain combined human-agent teams.. Agents can be divided into different types ranging from simple to ... "Agent-based Computing from Multi-agent Systems to Agent-Based Models: A Visual Survey" (PDF). Scientometrics. Springer. 89 (2 ...
... of fracture which initiate a systemic response that transport repairing agents to the fracture site thereby promoting autonomic ... To demonstrate the use of micro-vascular networks for autonomic healing, researchers developed a microvascular coating- ...
... the agents are transported to their biochemical sites of action in the central and autonomic nervous systems. Most general ... Clonidine premedication reduces the need for anaesthetic induction agents, for volatile agents to maintain general anaesthesia ... Other commonly used premedication agents include opioids such as fentanyl or sufentanil, gastrokinetic agents such as ... Despite newer anaesthetic agents and delivery techniques, which have led to more rapid onset of-and recovery from-anaesthesia ( ...
Whitestein Series in Software Agent Technologies and Autonomic Computing, published by Springer Science+Business Media Group ... Typically multi-agent systems research refers to software agents. However, the agents in a multi-agent system could equally ... Agents can be divided into types spanning simple to complex. Categories include: *Passive agents[6] or "agent without goals" ( ... Autonomous Agents and Multi-Agent Systems. 14 (1): 5-30. doi:10.1007/s10458-006-0012-0. Retrieved 2013-05-31.. [permanent dead ...
Tardive dyskinesia may reverse upon discontinuation of the offending agent or it may be irreversible, withdrawal may also make ... NMS is characterized by fever, muscle rigidity, autonomic dysfunction, and altered mental status. Treatment includes ... have largely supplanted the use of typical antipsychotics as first-line agents due to the higher risk of movement disorders in ... Adverse effects vary among the various agents in this class of medications, but common effects include: dry mouth, muscle ...
Also, contraction, as well as relaxation, can be induced by a number of physiochemical agents (e.g., hormones, drugs, ... neurotransmitters - particularly from the autonomic nervous system). Smooth muscle in various regions of the vascular tree, the ... A number of growth factors and neurohumoral agents influence smooth muscle growth and differentiation. The Notch receptor and ... various adrenergic receptors that explains the difference in why blood vessels from different areas respond to the same agent ...
E854 Accidental poisoning by other psychotropic agents E855 Accidental poisoning by other drugs acting on central and autonomic ... use E941 Drugs primarily affecting the autonomic nervous system causing adverse effects in therapeutic use E942 Agents ... adverse effects in therapeutic use E933 Primarily systemic agents causing adverse effects in therapeutic use E934 Agents ... in therapeutic use E944 Water mineral and uric acid metabolism drugs causing adverse effects in therapeutic use E945 Agents ...
With the advent of biologically inspired, pervasive, and autonomic computing, the advantages of, and necessity of, agent-based ... by focusing on the use of agents, and organizations (communities) of agents as the main abstractions. The field of Software ... and enhancing agent technology in such a way that it is more industrially applicable. Multiagent Systems Product Lines (MAS-PL ... Agent-Oriented Software Engineering (AOSE) is a new software engineering paradigm that arose to apply best practice in the ...
... and Dynamically Adaptable Services Diet Agents: Indefinitely scalable hosting for systems of autonomic interacting processes ... Autonomic Computing Autonomic system (computing) Cognitive networks Network Compartment The Autonomic Network Architecture (ANA ... Realising autonomics for Future Networks Autonomic Networking Wiki: A wiki dedicated to Autonomic Networking Autonomic ... Autonomic Networking follows the concept of Autonomic Computing, an initiative started by IBM in 2001. Its ultimate aim is to ...
... immunosuppressive agents like rituximab, myophenolate mofetil (Cellcept), or azathioprine (Imuran) or plasmapheresis. ... Vernino, Steven; Low, Phillip A. (2012). "Autoimmune Autonomic Ganglionopathy". Primer on the Autonomic Nervous System. pp. 489 ... Paola Sandroni & Phillip A. Low (2009). "Other Autonomic Neuropathies Associated with Ganglionic Antibody". Autonomic ... "Autonomic ganglia, acetylcholine receptor antibodies, and autoimmune ganglionopathy". Autonomic Neuroscience. 146 (1-2): 3-7. ...
... a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis". ... a new antihypertensive agent. I. Action on blood pressure and heart rate". Arzneimittel-Forschung 25 (10): 1557-1561. PMID ... a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute ...
... autonomic signalling, K+ channel subspecies, and molecular targets related to Ca2+ homeostasis. It now introduces new classes ... Class II agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers. Class III agents ... Class IV agents affect calcium channels and the AV node. Class V agents work by other or unknown mechanisms. With regard to ... Class I agents are called membrane-stabilizing agents, "stabilizing" referring to the decrease of excitogenicity of the plasma ...
... rather than by an external agent changing the setpoint of the controller. PCT also applies to nonliving autonomic systems. ...
"Dysautonomia , Autonomic Nervous System Disorders , MedlinePlus". NIH. Retrieved 2 January 2018.. *^ a b c d e f g h i j k l m ... anticholinergic agents such as trihexyphenidyl or scopolamine can be used, also intracutaneous injection of botulinum toxin ... Dysautonomia or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does not work properly. This ... autonomic failure, postural orthostatic tachycardia syndrome, and autonomic neuropathy.[citation needed] ...
Other anticholinergic agents that have tried to include propantheline bromide and benztropine.[citation needed] Injections of ... Reisfeld, Rafael (2006). "Sympathectomy for hyperhidrosis: Should we place the clamps at T2-T3 or T3-T4?". Clinical Autonomic ... In people with a past history of spinal cord injuries Autonomic dysreflexia Orthostatic hypotension Posttraumatic syringomyelia ... which cannot be managed by topical agents.[when?] A microwave-based device has been tried for excessive underarm perspiration ...
There are six main agent groups found in chemotherapy treatment that damage the sensory, motor, and autonomic neurons and ... These agents can damage dorsal root ganglia neurons by forming adducts with nuclear and mitochondrial DNA. This damage can ... Motor and autonomic symptoms are less frequent but possible. Symptoms may start days after the patient receives their first ... Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy ...
"Autonomic Dysreflexia in Spinal Cord Injury". eMedicine. Retrieved 14 July 2011. Flenady V, Wojcieszek AM, Papatsonis DN, Stock ... Nifedipine has been used frequently as a tocolytic (agent that delays premature labor). A Cochrane review has concluded that it ... to the avoidance of this practice is in the use of nifedipine for the treatment of hypertension associated with autonomic ...
Confirmation of a diagnosis of ACNES is warranted using an abdominal wall infiltration with a local anesthetic agent near the ... Patients frequently experience 'pseudovisceral' phenomena or symptoms of altered autonomic nervous system function including ... with the exception of some neuroleptic agents. ...
... autonomic, and sleep). Anticholinergic and dopaminergic agents can have adverse effects or result in psychosis in individuals ... Dysautonomia (autonomic dysfunction) occurs when Lewy pathology affects the peripheral autonomic nervous system (the nerves ... Lewy pathology affects the peripheral autonomic nervous system; autonomic dysfunction is observed less often in AD, ... Autonomic dysfunction resulting from damage to nerves in the heart in patients with DLB is associated with lower cardiac uptake ...
Autonomic Cardiovascular Damage during Post-menopause: the Role of Physical Training. Aging and Disease. 2013, 4 (6): 320-28. ... The STAR Trial: Evidence for Raloxifene as a Breast Cancer Risk Reduction Agent for Postmenopausal Women. J Natl Compr Canc ...
"CDC - The Emergency Response Safety and Health Database: Systemic Agent: BENZENE - NIOSH". www.cdc.gov. Archived from the ... Peripherally, the autonomic nervous system, especially the sympathetic nervous system, mediates many of the symptoms. Increased ... Anxiety disorder appears to be a genetically inherited neurochemical dysfunction that may involve autonomic imbalance; ...
Geoffrey Burnstock (1929-): Australian neurobiologist and President of the Autonomic Neuroscience Centre of the UCL Medical ... remembered for his identification of the bacterium Mycobacterium leprae in 1873 as the causative agent of leprosy.[147][148] ...
Other anticholinergic agents that have tried to include propantheline bromide and benztropine.[citation needed] ... Congenital autonomic dysfunction with universal pain loss. *Exposure to cold, notably associated with cold-induced sweating ... Reisfeld, Rafael (2006). "Sympathectomy for hyperhidrosis: Should we place the clamps at T2-T3 or T3-T4?". Clinical Autonomic ... which cannot be managed by topical agents.[when?][19][20] ...
Autonomic nervous system). . ഇത് കേന്ദ്രനാഡീ വ്യൂഹത്തിൽ നിന്നും പൂർണമായും സ്വതന്ത്രമല്ല. ഈ വ്യൂഹത്തിൽ പ്രധാനമായും രണ്ട് ...
Several classes of antihypertensive agents are recommended, with the choice depending on the cause of the hypertensive crisis, ... Other common causes of hypertensive crises are autonomic hyperactivity such as pheochromocytoma, collagen-vascular diseases, ... Other intravenous agents like nitroglycerine, nicardipine, labetalol, fenoldopam or phentolamine can also be used, but all have ... the blood pressure should be slowly lowered over a period of minutes to hours with an antihypertensive agent. ...
Selectivity of antidepressant agents are based on the neurotransmitters that are thought to influence symptoms of depression.[ ... autonomic instability with fluctuating vital signs, and mental status changes that include extreme agitation progressing to ... Agents with dual serotonin and norepinephrine reuptake inhibition (SNRIs) are sometimes called non-tricyclic serotonin and ... Combination of mechanisms of action in a single active agent is an important development in psychopharmacology.[28] ...
In such cases it may be helpful to use thickening agents for liquid intake and an upright posture when eating, both measures ... Alterations in the autonomic nervous system can lead to orthostatic hypotension (low blood pressure upon standing), oily skin ... Hornykiewicz O (2002). "L-DOPA: from a biologically inactive amino acid to a successful therapeutic agent". Amino Acids. 23 (1- ... Agents currently under investigation include anti-apoptotics (omigapil, CEP-1347), antiglutamatergics, monoamine oxidase ...
It may be used as a nasal/sinus decongestant, as a stimulant,[119] or as a wakefulness-promoting agent.[120] ... that is they stimulate the sympathetic branch of the autonomic nervous system. This leads to effects such as mydriasis, ... Tashkin, D. P. (1 March 2001). "Airway effects of marijuana, cocaine, and other inhaled illicit agents". Current Opinion in ... and anorectic agent.[112] It is commonly used in prescription and over-the-counter cough and cold preparations. In veterinary ...
Available agents[edit]. Main article: List of antineoplastic agents. There is an extensive list of antineoplastic agents. ... Though the symptoms are mainly sensory, in some cases motor nerves and the autonomic nervous system are affected.[99] CIPN ... Alkylating agents[edit]. Main article: Alkylating antineoplastic agent. Alkylating agents are the oldest group of ... Siddik ZH (2005). Mechanisms of Action of Cancer Chemotherapeutic Agents: DNA-Interactive Alkylating Agents and Antitumour ...
Bennett MR (June 1999). "One hundred years of adrenaline: the discovery of autoreceptors". Clinical Autonomic Research. 9 (3): ... "Part 6: Advanced Cardiovascular Life Support Section 6: Pharmacology II: Agents to Optimize Cardiac Output and Blood Pressure ... contrast agents, medicines or people with a history of anaphylactic reactions to known triggers. A single dose is recommended ... prolong the action of the anesthetic agent. Due to epinephrine's vasoconstricting abilities, the use of epinephrine in ...
These are geared towards lay readers, not readers who are technically proficient. Do not replace easy to understand lay variants (e.g. "smell") with difficult variants lay readers will not understand (e.g. "olfaction ...
Recent reports on recombinant PYY 3-36 suggest that this agent may contribute to weight loss by suppressing appetite. ... and both the central and autonomic nervous systems.[5] The circulating gut hormones that regulate many pathways in the body can ... the activity of the parasympathetic autonomic nervous system), stimulation of the thyroid (thyroxine regulates the metabolic ...
Examples of endogenous factors include the autonomic nervous system, circulating hormones, and intrinsic mechanisms inherent to ... thereby safely concentrating the anesthetic agent for an extended duration, as well as reducing hemorrhage.[3] ... "Vasoconstrictor agents for local anesthesia". Anesth Prog. 42 (3-4): 116-20. PMC 2148913. PMID 8934977 ...
The autonomic nervous system's physiological state (see below) leading to loss of consciousness may persist for several minutes ... Central agents. *Mechanical device. *Discontinuation of medications known to lower blood pressure may be helpful, but stopping ...
M1 and M4 subtypes are more abundant in brain and autonomic ganglia. M1, M3 and M5 interact with Gq proteins to stimulate ... Muscarinic antagonists are often called parasympatholytics because they have the same effect as agents that block ... The M2 and M3 subtypes mediate muscarinic responses at peripheral autonomic tissues. ...
This changes the blood flow to downstream organs, and is determined by the autonomic nervous system. Vasodilation and ... It is regulated by vasoconstrictors (agents that cause vasoconstriction). These include paracrine factors (e.g. prostaglandins ...
Contact with certain chemicals, including pulmonary agents (such as phosgene) and blood agents (such as hydrogen cyanide) ... Congenital central hypoventilation syndrome, or primary alveolar hypoventilation, a disorder of the autonomic nervous system in ...
In practice, each individual's autonomic nervous system and other systems regulating blood pressure, notably the kidney,[65] ... also contributes to changing the caliber of small blood vessels and influencing resistance and reactivity to vasoactive agents. ... However, this varies with the individual and is highly dependent on autonomic nervous system response and the renin-angiotensin ... Normally this is compensated for by multiple mechanisms, including activation of the autonomic nervous system which increases ...
Triggle, David J. (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.. ... Buccafusco JJ, Shuster LC, Terry AV (2007). „Disconnection between activation and desensitization of autonomic nicotinic ...
Vanderbilt Autonomic Dysfunction Cente. "Multiple System Atrophy / Shy Drager Syndrome". Retrieved May 29, 2010.. ... A study in 2018 suggests a post-translationally modified form of the protein called alpha-synuclein may be a causal agent for ... Autonomic Dysfunction Center at Vanderbilt University. *The European MSA Study Group, an Innsbruck-based European MSA Study ... Autonomic nervous system dysfunction (impaired automatic body functions) including:. *postural or orthostatic hypotension, ...
Monforte R, Estruch R, Valls-Solé J, Nicolás J, Villalta J, Urbano-Marquez A (1995). "Autonomic and peripheral neuropathies in ... "Use of anesthetic agents in neonates and young children.". Anesth Analg 104 (3): 509-20. doi:10.1213/01.ane.0000255729.96438. ...
Bevers TB (September 2007). "The STAR trial: evidence for raloxifene as a breast cancer risk reduction agent for postmenopausal ... "Autonomic Cardiovascular Damage during Post-menopause: the Role of Physical Training". Aging and Disease. 4 (6): 320-8. doi ...
The movement and the flow of chemicals into the stomach are controlled by both the autonomic nervous system and by the various ... and bacterial agents.[22] ...
"Antimicrob Agents Chemother. 42 (12): 3245-50. PMC 106029. PMID 9835521.. *^ Dubner S, Schapachnik E, Riera AR, Valero E (2008 ... Autonomic disease imparted by Chagas may eventually result in megaesophagus, megacolon and accelerated dilated cardiomyopathy. ... "Antimicrob Agents Chemother. 49 (4): 1521-8. doi:10.1128/AAC.49.4.1521-1528.2005. PMC 1068607. PMID 15793134.. ... Agents Chemother. 56 (1): 115-123. doi:10.1128/AAC.05135-11. PMC 3256028. PMID 22037852. Archived from the original on 6 April ...
"Wall Paint, Perfumes and Cleaning Agents Are Polluting Our Air". Npr.org. Retrieved 12 March 2019.. ... Other mechanisms such as autonomic nervous system imbalance have also been suggested.[60][61] ...
... has been recognized as a potential agent for use in bioterrorism.[79] It can be absorbed through the eyes, ... he concluded that the toxin acts by interrupting signal transmission in the somatic and autonomic motor systems, without ... University-based ophthalmologists in the US and Canada further refined the use of botulinum toxin as a therapeutic agent. By ... The effects of botulinum toxin are different from those of nerve agents involved insofar in that botulism symptoms develop ...
PMA acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters. However ... Effects of 3,4-methylenedioxymethamphetamine and related amphetamines on autonomic and behavioral thermoregulation. ...
I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer ... the activation of superior salivary nucleus in the brainstem is used to stimulate the trigeminal autonomic reflex arc, causing ... Indometacin is an effective tocolytic agent,[14] able to delay premature labor by reducing uterine contractions through ... "Indomethacin: A New Non-steroid Anti-inflammatory Agent". British Medical Journal. 2 (5363): 965-70. doi:10.1136/bmj.2.5363. ...
"Autoantibodies to autonomic nerves associated with cardiac and peripheral autonomic neuropathy". Diabetes Care. 28 (8): 1959-64 ... Cyclosporine A, an immunosuppressive agent, has apparently halted destruction of beta cells (on the basis of reduced insulin ... an antineoplastic agent, is selectively toxic to the beta cells of the pancreatic islets. It is used in research for inducing ... Environmental triggers and protective factors under research include dietary agents such as proteins in gluten,[27] time of ...
0009] A therapeutic agent (U.S. Pat No. 2,777,908) for pancreatitis having a zinc salt of carnosine as an active ingredient has ... Since the autonomic nervous system is responsible for the control of blood glucose level, the control of blood pressure, the ... Therapeutic Agents For Overactive Bladder. February, 2008. Horie et al.. 20050009868. Retinoid receptor pan-antagonists for ... Previous Patent: Agent for diagnosing and treating malignant tumors. Next Patent: Glucagon antagonists/inverse agonists ...
Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery. *Carpal Tunnel Syndrome ...
Application of Autonomic Agents for Global Information Grid Management and Security. Donald Cox, Youssif Al-Nashif and Salim ... In this paper we explore the GIG and present an innovative application of Autonomic Agent technology currently in development ... is proving useful in simulating GIG operation at the node level for the analysis of agent-based detection and neutralization of ...
Study Autonomic Agents flashcards from Mary Potkonjak ... Autonomic Agents Flashcards Preview Random First Aid Sections ...
An unsatisfactory Alice exchange may lead to self-destruction of the anonymous autonomous agent for self-protection. ... In another embodiment an asynchronous Alice signal (Autonomic license) requiring valid credentials of an anonymous autonomous ... Systems, methods and apparatus are provided through which in some embodiments an autonomic entity manages a system by ... a messenger autonomic agent for facilitating communication between the coordinating autonomic agent, plurality of autonomic ...
Antihypertensive Agents. Ganglionic Blockers. Autonomic Agents. Peripheral Nervous System Agents. Physiological Effects of ... an autonomic dysfunction questionnaire, a physical examination (including an autonomic assessment and specialty SCI exam), ... Mecamylamine for Autonomic Dysreflexia Prophylaxis. The safety and scientific validity of this study is the responsibility of ... Autonomic Dysreflexia. Spinal Cord Diseases. Central Nervous System Diseases. Nervous System Diseases. Trauma, Nervous System. ...
Autonomic Agents. LinkOut - more resources. Full Text Sources. *Taylor & Francis. Medical. *Anxiety - MedlinePlus Health ... Psychological and autonomic effects of art making in college-aged students.. Sandmire DA1, Rankin NE2, Gorham SR3, Eggleston DT ... Anxiety; State-Trait Anxiety Inventory; art making; autonomic nervous system; heart rate variability ...
Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of Pharmacological Action. Physiological Effects of Drugs. ... Pure Autonomic Failure. Pathological Conditions, Anatomical. Primary Dysautonomias. Autonomic Nervous System Diseases. Nervous ... Norepinephrine Transporter Blockade, Autonomic Failure. The safety and scientific validity of this study is the responsibility ... associated with impaired autonomic reflexes as assessed by autonomic function tests. ...
... and development toolsPlanning for and implementing autonomic technologyCurrent autonomic solutions from IBM and other leading ... automaticallyUsing autonomic computing to reduce costs, improve services, and enhance agilityAutonomic components, ... Software Agents. Autonomic Agent Technology. Summary and Conclusions. Note. 13. Independent Software Vendors. Challenging Times ... AUTONOMIC COMPUTING-MORE DETAIL. 8. AC Architectures. Introduction. Control Loops. Autonomic Component Description. Autonomic ...
Autonomic Agents / immunology* * Drug-Related Side Effects and Adverse Reactions / etiology* * Drug-Related Side Effects and ... Autonomic dysfunction and HPV immunization: an overview Immunol Res. 2018 Dec;66(6):744-754. doi: 10.1007/s12026-018-9036-1. ... Keywords: Autoimmunity; Autonomic dysfunction; Chronic fatigue syndrome; Chronic regional pain syndrome; Fibromyalgia; HPV ... This article proposes that vaccine-triggered, immune-mediated autonomic dysfunction could lead to the development of de novo ...
While high dose results in seizure and death, low dose exposure may lead to autonomic imbalance and chronic cardiac pathologies ... Results also indicate altered stress responsiveness of HPA indicating autonomic imbalance. The role of low-dose sarin/ ... organophosphate exposure needs to be considered in military and civilian population who suffer from autonomic imbalance and/or ... a lethal chemical nerve agent, may be a causative factor in multifactorial syndrome implicated in the Gulf War and Tokyo ...
Nicotine is classified as a stimulant of autonomic ganglia. Nicorette Absorption Absorption of nicotine through the buccal ... Nicotine, the primary alkaloid in tobacco products binds stereo-selectively to nicotinic-cholinergic receptors on autonomic ...
Reproductive Control Agents. Physiological Effects of Drugs. Contraceptive Agents, Female. Mineralocorticoid Receptor ... Assessment of Autonomic Tone in Normotensive Women Using Combined Hormonal Oral Contraceptive Containing Drospirenone. The ... Contraceptive Affecting the Autonomic Nervous System Contraceptive Affecting Blood Pressure Drug: Contraceptives, Oral, ... It is possible that changes in autonomic nervous system are involved. The objective of these study was to evaluate the effect ...
... book constitutes the thoroughly refereed post-conference proceedings of the thirs International ICST conference on Autonomic ... A-OSGi Host autonomic computing autonomic systems business applications cognitive agents communication communication system ... Integrating Autonomic Grid Components and Process-Driven Business Applications Thomas Weigold, Marco Aldinucci, Marco Danelutto ... Autonomic Computing and Communications Systems. Third International ICST Conference, Autonomics 2009, Limassol, Cyprus, ...
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Autonomic Agents. *Cholinergic Agents. *Cholinergic Agonists. *Cholinergic Receptor Agonist. *Cytochrome P-450 CYP2A6 ...
A Dynamically Adjustable Autonomic Agent Framework. Pages 631-642. Mostafa, Salama A. (et al.) ... Improving Public Transport Management: A Simulation Based on the Context of Software Multi-agents ...
AUTONOMIC NERVOUS SYSTEM AGENTS; BODY; CARBOHYDRATES; CARBOXYLIC ACIDS; CARDIOTONICS; CARDIOVASCULAR AGENTS; CENTRAL NERVOUS ...
Autonomic nerve regulating agent. US20050032720 *. 6 Ago 2003. 10 Feb 2005. Regenacorp, Inc.. Method and composition for ... External skin treatment agent composition containing isocarbacyclins as active ingredient. US5714482 *. 5 Jun 1995. 3 Feb 1998 ... Enhancing tissue penetration of physiologically active agents with dmso. US4061670 *. 19 Jul 1976. 6 Dic 1977. American ... Protective prostaglandins for use in conjunction with chemotherapeutic agents. US5656663 *. 3 Feb 1994. 12 Ago 1997. Teijin ...
ANTI-INFECTIVE AGENTS; ANTIBIOTICS; ANTINEOPLASTIC DRUGS; AROMATICS; AUTONOMIC NERVOUS SYSTEM AGENTS; BODY; BRAIN; ... CARBOHYDRATES; CARDIAC GLYCOSIDES; CARDIOTONICS; CARDIOVASCULAR AGENTS; CELL CONSTITUENTS; CENTRAL NERVOUS SYSTEM; CHARGED ...
Autonomic Agents - Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018 - Autonomic Agents Drug ...
"Agents Acting at the Neuromuscular Junction and Autonomic Ganglia." Goodman and Gilmans Manual of Pharmacology and ... Agents Acting at the Neuromuscular Junction and Autonomic Ganglia. In: Hilal-Dandan R, Brunton LL. Hilal-Dandan R, & Brunton L. ... Agents acting at the neuromuscular junction and autonomic ganglia. Hilal-Dandan R, Brunton LL. Hilal-Dandan R, & Brunton L.L.( ... receptor mediates neurotransmission postsynaptically at the neuromuscular junction and peripheral autonomic ganglia; in the CNS ...
Chapter 11: Nicotine and Agents Acting at the Neuromuscular Junction and Autonomic Ganglia ... "Nicotine and Agents Acting at the Neuromuscular Junction and Autonomic Ganglia." Goodman & Gilmans: The Pharmacological Basis ... Nicotine and Agents Acting at the Neuromuscular Junction and Autonomic Ganglia. In: Brunton LL, Hilal-Dandan R, Knollmann BC. ... Nicotine and agents acting at the neuromuscular junction and autonomic ganglia. Brunton LL, Hilal-Dandan R, Knollmann BC. ...
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Agents to control autonomic nervous system instability may be required. Initiate active immunization concurrently with ... Seizures may occur, and the autonomic nervous system may also be affected. ...
autonomic nervous system. *parasympathetic nervous system. *autonomic agents. *exercise physiology. *BNP, brain natriuretic ... Modulation of cardiac autonomic activity during and immediately after exercise. Am J Physiol1989;256:H132-41. ... Autonomic contribution to heart rate recovery from exercise in humans. J Appl Physiol1982;53:1572-5. ... Exercise and autonomic function in health and cardiovascular disease. Cardiol Clin2001;19:369-87. ...
Whitestein Series in Software Agent Technologies and Autonomic Computing. Copyright. 2010. Publisher. Birkhäuser Basel. ...
... , Neuromuscular Blockade, Non-depolarizing Neuromuscular Blocking Agent, Depolarizing Neuromuscular Blocking ... Paralytic Agent. Neurology Book * Pharmacology Chapter Autonomic Nervous System Disorders * Adrenergic Receptor ... Paralytic Agent. Aka: Paralytic Agent, Neuromuscular Blockade, Non-depolarizing Neuromuscular Blocking Agent, Depolarizing ... Non-depolarizing agents (Acetylcholine antagonists). *Prototype: Curare. *Agents used clinically. *Rocuronium (Rapid Sequence ...
Autonomic Agents / pharmacology*. Diagnostic Techniques, Urological. Efferent Pathways / drug effects*, physiology. Electric ... 0/Autonomic Agents; 0/Enzyme Inhibitors; 0/Nicotinic Antagonists; 19216-56-9/Prazosin; 50903-99-6/NG-Nitroarginine Methyl Ester ...
Anti-Mycobacterial Agents (0) see Anti-Bacterial Agents. Anti-Obesity Agents (24) • Agents that increase energy expenditure and ... Antithrombotic Agents (0) see Fibrinolytic Agents. Antithyroid Agents (10) • Agents that are used to treat hyperthyroidism by ... Antifibrillatory Agents (0) see Anti-Arrhythmia Agents. Antifibrinolytic Agents (7) • Agents that prevent fibrinolysis or lysis ... Antitrichomonal Agents (6) • Agents used to treat trichomonas infections. MeSH. Antitubercular Agents (33) • Drugs used in the ...
  • Nicotine, the primary alkaloid in tobacco products binds stereo-selectively to nicotinic-cholinergic receptors on autonomic ganglia, the adrenal medulla, neuromuscular junctions and in the brain. (pharmacycode.com)
  • Nicotine is classified as a stimulant of autonomic ganglia. (pharmacycode.com)
  • Distinct subtypes of nicotinic receptors exist at the neuromuscular junction (N m ), in autonomic ganglia, and in the CNS (the neuronal form, N n ). (mhmedical.com)
  • These cells migrate and eventually evolve into sensory and autonomic ganglia as well as the adrenal chromaffin cells. (aappublications.org)
  • A substance that blocks nerve impulses in autonomic ganglia. (dictionary.com)
  • After signing the informed consent form, at visit 1, subjects will complete an interview to evaluate past medical history, an autonomic dysfunction questionnaire, a physical examination (including an autonomic assessment and specialty SCI exam), vital signs measurement, and baseline testing of the electrical activity of the heart (electrocardiography or ECG testing). (clinicaltrials.gov)
  • This article proposes that vaccine-triggered, immune-mediated autonomic dysfunction could lead to the development of de novo post-HPV vaccination syndrome possibly in genetically susceptible individuals. (nih.gov)
  • To illustrate further the breadth and complexities of autonomic dysfunction, some pediatric disorders are described, concentrating on those that present at birth or appear in early childhood. (aappublications.org)
  • Now, more than 20 years later, investigators are beginning to appreciate the value of genetic autonomic disorders as models to advance the understanding of pathophysiologic mechanisms involved in autonomic dysfunction. (aappublications.org)
  • 6 , 7 In fact, the original description of FD in 1949 8 preceded the description by Shy and Drager 9 of the adult neurodegenerative syndrome characterized by central autonomic dysfunction by 11 years. (aappublications.org)
  • 2 , 3 We provide an overview of the ANS and stress the extent of its influence, discuss the protean symptoms and manifestations caused by autonomic perturbations, and emphasize the expanding number of pediatric disorders that feature autonomic dysfunction. (aappublications.org)
  • Major anesthetic concerns in these patients include respiratory compromise, bulbar and autonomic dysfunction, and an increased risk of thromboembolism. (renalandurologynews.com)
  • 8 Considering that this disease reflects degenerative autonomic dysfunction, restoration of normal blood pressure responses is not a realistic treatment goal. (ajmc.com)
  • First-Generation Agents - block autonomic receptors. (nmmra.org)
  • It is possible that changes in autonomic nervous system are involved. (clinicaltrials.gov)
  • To compare changes in autonomic nervous activity in healthy senior individuals while walking with and without a dog, and during routine activities at home and periods of interacting with the dog at home. (mja.com.au)
  • Atomoxetine could be a new therapeutic alternative for the treatment of NOH in patients with autonomic failure, particularly those with multiple system atrophy (MSA). (clinicaltrials.gov)
  • 1,2 In comparison, neurogenic orthostatic hypotension (NOH) is a rare disorder that occurs primarily in patients already given a diagnosis of a degenerative disease such as Parkinson's disease (PD), diffuse Lewy body disease, pure autonomic failure, or multiple system atrophy (MSA). (ajmc.com)
  • ganglionic blocking agent one that blocks nerve impulses at autonomic ganglionic synapses. (thefreedictionary.com)
  • Dexmedetomidine, an α2-agonist, serves as a potential adjunctive agent through management of associated autonomic symptoms. (nih.gov)
  • Acetylcholinesterase inhibitors increase parasympathetic neurotransmission through inhibition of the enzymatic breakdown of acetylcholine at cholinergic receptor sites in the autonomic nervous system. (bmj.com)
  • cholinergic blocking agent one that blocks or inactivates acetylcholine . (thefreedictionary.com)
  • cholinergic and parasympathomimetic agents can be divided into three groups, 1. (scribd.com)
  • To reverse neuromuscular blockade, administer a cholinesterase inhibitor (e.g., neostigmine, pyridostigmine, edrophonium) in conjunction with an anticholinergic agent such as atropine or glycopyrrolate to block adverse muscarinic effects of the cholinesterase inhibitor. (drugs.com)
  • adrenergic blocking agent one that inhibits response to sympathetic impulses by blocking the alpha (alpha-adrenergic blocking a.) or beta (beta-adrenergic blocking a.) receptor sites of effector organs. (thefreedictionary.com)
  • 1 Among the major manifestations of neuroendocrine dysregulation are profound abnormalities in autonomic control, characterised by sympathetic overactivity and parasympathetic withdrawal. (bmj.com)
  • Since CHF is characterised by withdrawal of parasympathetic tone, cholinesterase inhibition may restore autonomic balance with augmentation of parasympathetic neurotransmission. (bmj.com)
  • As variability in the autonomic nervous system plays a crucial role in almost every vital function, 10 analysing the oscillations of parasympathetic neural activity, equated with cardiac vagal tone, would conceivably shed light on the physiological effects a pet dog might have on a person walking the dog or patting the dog. (mja.com.au)
  • Animal data suggest that nitric oxide (NO) acts as a neuromodulator not only within the central nervous system but also within peripheral autonomic pathways controlling cardiac function to provide a net enhancement of parasympathetic and inhibition of sympathetic control. (ahajournals.org)
  • 10 The NO generated at these peripheral cardiac autonomic sites appears to enhance not only the heart rate response to vagus (parasympathetic) nerve stimulation 11-14 (although not in all species 11 ) but also parasympathetic antagonism of cardiac sympathetic responses (indirect activity). (ahajournals.org)
  • Appreciation of the breadth of autonomic disorders has increased since Langley 1 originally proposed the generic term "autonomic nervous system" (ANS) and designated its division into the sympathetic, parasympathetic, and enteric nervous systems. (aappublications.org)
  • We tested the hypotheses that the glucagon response to hypoglycemia is reduced in patients who are approaching the insulin-deficient end of the spectrum of type 2 diabetes and that recent antecedent hypoglycemia shifts the glycemic thresholds for autonomic (including adrenomedullary epinephrine) and symptomatic responses to hypoglycemia to lower plasma glucose concentrations in type 2 diabetes. (diabetesjournals.org)
  • Reduced autonomic (including adrenomedullary epinephrine) and symptomatic responses also cause the clinical syndrome of hypoglycemia unawareness ( 1 ). (diabetesjournals.org)
  • The concept of hypoglycemia-associated autonomic failure in type 1 diabetes ( 7 , 10 , 11 ) posits that recent antecedent iatrogenic hypoglycemia causes both defective glucose counterregulation (by reducing the epinephrine response in the setting of an absent glucagon response) and hypoglycemia unawareness (by reducing the autonomic and thus the neurogenic symptom response). (diabetesjournals.org)
  • This chapter reviews different approaches for the development of new models, architectures and real applications of physical agents. (springer.com)
  • The chapter starts by identifying this kind of agents and their main requirements. (springer.com)
  • While high dose results in seizure and death, low dose exposure may lead to autonomic imbalance and chronic cardiac pathologies. (wright.edu)
  • The voluntary nervous system governs the striated or skeletal muscles, whereas the autonomic nervous system governs the glands, cardiac muscle, and smooth muscles such as those of the digestive system, respiratory system, and skin. (thefreedictionary.com)
  • positive inotropic agents increase, and negative inotropic agents decrease the force of cardiac muscle contraction. (thefreedictionary.com)
  • Autonomic regulation of the heart has an important influence on prognosis in cardiac disease. (ahajournals.org)
  • 3. The composition according to claim 2 wherein said disease conditions resulting from disturbances in the autonomic nervous system are hypertension or high blood sugar symptoms caused due to the enhancement of the activity of the sympathetic nerve system. (freepatentsonline.com)
  • This is a preliminary study of the antihypertensive drug mecamylamine, used in the specific circumstance of hypertension caused by autonomic dysreflexia (AD), a condition that affects people with spinal cord injury (SCI). (clinicaltrials.gov)
  • We speculate that these agents may be effective because of the inhibitory effect of carbamazepine and diphenylhydantoin on brainstem activity, although the actual level of the reflex arc affected by these drugs is not known [2, 3] . (annals.org)
  • Sedation - common effect ?Effect: oSufficiently prominent with some agents to make them useful as "sleep aids" and unsuitable for daytime use oResembles that of some antimuscarinic drugs and is considered very different from the disinhibited sedation produced by sedative-hypnotic drugs. (nmmra.org)
  • Alkylamines - widely use drugs in the USA and the second-generation nonsedating agents. (nmmra.org)
  • Topics include autonomic and central nervous system agents, anti-inflammatory agents, and anti-infective drugs. (vgcc.edu)
  • Most cases occur in patients receiving multiple agents that effect serotonin activity or from significant exposure to certain serotonergic drugs. (renalandurologynews.com)
  • The composition preferably has an effect of controlling the autonomic nervous system, and more specifically it has an effect of preventing, improving or alleviating disturbances in the autonomic nervous system and disease conditions resulting therefrom. (freepatentsonline.com)
  • 2. A composition having an effect of controlling the autonomic nervous system that prevents, improves or alleviates disturbances in the autonomic nervous system and disease conditions resulting therefrom, said composition comprising carnosine in an amount to provide 0.7 μg/kg to 0.09 mg/kg of carnosine per ingestion. (freepatentsonline.com)
  • 7. A method of preventing, improving or alleviating disturbances in the autonomic nervous system, and disease conditions resulting therefrom, comprising ingesting carnosine in an amount to provide 0.7 μg/kg to 0.09 mg/kg per ingestion. (freepatentsonline.com)
  • 11. The use of carnosine for producing a composition that prevents, improves or alleviates disturbances in the autonomic nervous system, and disease conditions resulting therefrom, by allowing carnosine to be ingested so that the amount ingested is 0.7 μg/kg to 0.09 mg/kg per ingestion. (freepatentsonline.com)
  • However, autonomic disturbances then become a major problem. (bmj.com)
  • 2- 5 Inhibition of sympathetic overactivity with β adrenergic receptor blocking agents improved survival in clinical trials in patients with CHF but there are few previous clinical investigations of parasympathomimetic agents in heart failure populations. (bmj.com)
  • Circumstances that can trigger autonomic dysreflexia are often related to stimulation of the bladder, bowel, and skin of the patient. (thefreedictionary.com)
  • Once the symptoms of autonomic dysreflexia are manifest, emergency care is indicated. (thefreedictionary.com)
  • this prevents increasing the stimulus to autonomic dysreflexia. (thefreedictionary.com)
  • Because the glucagon response to falling plasma glucose levels is virtually absent and the glycemic thresholds for autonomic and symptomatic responses to hypoglycemia are shifted to lower glucose concentrations by recent antecedent hypoglycemia, patients with advanced type 2 diabetes, like those with type 1 diabetes, are at risk for hypoglycemia-associated autonomic failure and the resultant vicious cycle of recurrent iatrogenic hypoglycemia. (diabetesjournals.org)
  • Sarin, a lethal chemical nerve agent, may be a causative factor in multifactorial syndrome implicated in the Gulf War and Tokyo terrorist attacks. (wright.edu)
  • A review of nerve agent exposure for the critical care physician. (cdc.gov)
  • Somani SM, Husain K. Low-level nerve agent toxicity under normal and stressful conditions. (cdc.gov)
  • Chronic neurobehavioral and central and autonomic nervous system effects of Tokyo subway sarin poisoning. (cdc.gov)
  • The clinical findings form a triad of mental status changes, autonomic instability and neuromuscular hyperactivity. (renalandurologynews.com)
  • The diagnosis of serotonin syndrome is a clinical diagnosis based on mental status changes, neuromuscular hyperactivity, and autonomic instability in a patient with serotonergic drug exposure. (renalandurologynews.com)
  • oxidizing agent a substance capable of accepting electrons from another substance, thereby oxidizing the second substance and itself becoming reduced. (thefreedictionary.com)
  • psychoactive agent , psychotropic agent psychoactive substance . (thefreedictionary.com)
  • reducing agent a substance that acts as an electron donor in a chemical redox reaction . (thefreedictionary.com)
  • surface-active agent a substance that exerts a change on the surface properties of a liquid, especially one that reduces its surface tension, as a detergent. (thefreedictionary.com)
  • wetting agent a substance that lowers the surface tension of water to promote wetting. (thefreedictionary.com)
  • Second-generation antipsychotic agents may occasionally induce an increase in blood pressure even in the absence of overweight. (aappublications.org)
  • Despite escalating doses of benzodiazepines, published literature indicates that some patient's alcohol withdrawal syndrome symptoms do not respond, and that the use of adjunctive agents may be beneficial in these patients. (nih.gov)
  • This book introduces Autonomic Computing. (informit.com)
  • This concept is a cornerstone of IBM's strategic initiative, and it offers great promise because autonomic computing systems have the ability to manage themselves and dynamically adapt to change in accordance with evolving or dynamic business policies and objectives. (informit.com)
  • Autonomic Computing-Why Now? (informit.com)
  • Is Autonomic Computing New? (informit.com)
  • Is Autonomic Computing Working Today? (informit.com)
  • Autonomic Computing: One Answer to Complexity. (informit.com)
  • Skills Management for Autonomic Computing. (informit.com)
  • 9. Autonomic Computing and Open Standards. (informit.com)
  • Important Standards for Autonomic Computing. (informit.com)
  • This book constitutes the thoroughly refereed post-conference proceedings of the thirs International ICST conference on Autonomic Computing and Communication Systems, Autonomics 2009, held in Cyprus Univesity of Technology, Limassol, Cyprus, in September 2009. (springer.com)
  • The 11 revised full papers out of 26 submitted and hosted 5 invited talks, covering various aspects of autonomic computing including application, middelware, networking protocols and evaluation. (springer.com)
  • Autonomic computing (AC) refers to the self-managing characteristics of distributed computing resources, adapting to unpredictable changes while hiding intrinsic complexity to operators and users. (wikipedia.org)
  • An autonomic computing framework is composed of autonomic components (AC) interacting with each other. (wikipedia.org)
  • They state the essence of autonomic computing is system self-management, freeing administrators from low-level task management while delivering better system behavior. (wikipedia.org)
  • The Autonomic Computing Initiative (ACI) aims at providing the foundation for autonomic systems. (wikipedia.org)
  • Typically multi-agent systems research refers to software agents . (wikipedia.org)
  • Benefits of autonomous agent approach to manufacturing systems control. (springer.com)
  • however, a neuromuscular blocking agent with a rapid onset of action (e.g., succinylcholine, rocuronium) generally preferred in emergency situations when rapid intubation is required. (drugs.com)
  • neuromuscular blocking agent a compound that causes paralysis of skeletal muscle by blocking neural transmission at the neuromuscular junction . (thefreedictionary.com)
  • Multi-agent systems can manifest self-organisation as well as self-steering and other control paradigms and related complex behaviors even when the individual strategies of all their agents are simple. (wikipedia.org)
  • Both substances are key stimulatory components of the sympathetic nervous system (part of the autonomic nervous system ), hence their pharmacological classification as sympathomimetic agents. (britannica.com)
  • The most universally respected and read medical text in all of pharmacology, Goodman & Gilman?s The Pharmacological Basis of Therapeutics represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. (abebooks.co.uk)
  • Propranolol is a nonselective, beta-adrenergic receptor-blocking agent possessing no other autonomic nervous system activity. (drugs.com)
  • It specifically competes with beta-adrenergic receptor-stimulating agents for available receptor sites. (drugs.com)
  • INDERAL XL contains propranolol hydrochloride, a nonselective, beta-adrenergic receptor-blocking agent for oral administration, as an extended- release product. (rxlist.com)
  • The active ingredient in INDERAL XL is a synthetic beta-adrenergic receptor-blocking agent chemically described as 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride. (rxlist.com)
  • blocking agent an agent that inhibits a biological action, such as movement of an ion across the cell membrane, passage of a neural impulse, or interaction with a specific receptor. (thefreedictionary.com)
  • Purpose: Dextofisopam is a non-serotonergic agent thought to modulate autonomic function via a novel hypothalamic receptor, resulting in decreased stimulated autonomic activity. (rti.org)
  • However, the estimated prevalence of asymptomatic vCJD in populations exposed to the BSE agent is uncertain ( 4 ). (cdc.gov)
  • Therefore, one could postulate that an early genetic error affecting initial migration would cause profound decreases in both sensory and autonomic populations, whereas a later genetic error might only affect cell survival to one or both populations, causing more erratic and varied clinical expression. (aappublications.org)
  • Enriched by a new full-color presentation and updated to reflect all critical new developments in drug action and drug-disease interaction, the twelfth edition includes more than 440 color illustrations depicting key principles and actions of specific pathways and therapeutic agents. (abebooks.co.uk)
  • an autonomic reflex. (thefreedictionary.com)
  • The exact mechanism by which these agents suppress the autonomic reflex involving syncope is unknown. (annals.org)
  • Dimercaprol (BAL), which chelates mercury, was quickly introduced as a therapeutic agent in 1948 but has given variable results. (nap.edu)
  • Driven by such vision, a variety of architectural frameworks based on "self-regulating" autonomic components has been recently proposed. (wikipedia.org)
  • Despite the presence of regulatory components from both arms of the autonomic nervous system, at day 12 [60% of the incubation period (60%I)] embryonic white leghorn chickens ( Gallus gallus ) possess only a tonic adrenergic stimulation of the cardiovascular system ( Crossley and Altimiras, 2000 ). (biologists.org)
  • The goal of this review is to increase awareness of the expanding spectrum of pediatric autonomic disorders by providing an overview of the autonomic nervous system, including the roles of its various components and its pervasive influence, as well as its intimate relationship with sensory function. (aappublications.org)
  • The role of low-dose sarin/organophosphate exposure needs to be considered in military and civilian population who suffer from autonomic imbalance and/or cardiomyopathies of indeterminate origin. (wright.edu)
  • Some autonomic systems involve mobile agents interacting via loosely coupled communication mechanisms. (wikipedia.org)
  • All subjects were screened with a medical history, physical examination, and standard battery of autonomic tests ( 12 ). (diabetesjournals.org)