Transplant comprised of an individual's own tissue, transferred from one part of the body to another.
Transplantation of an individual's own tissue from one site to another site.
The grafting of bone from a donor site to a recipient site.
A valve situated at the entrance to the pulmonary trunk from the right ventricle.
Procedures used to reconstruct, restore, or improve defective, damaged, or missing structures.
The largest of three bones that make up each half of the pelvic girdle.
An abnormal triangular fold of membrane in the interpalpebral fissure, extending from the conjunctiva to the cornea, being immovably united to the cornea at its apex, firmly attached to the sclera throughout its middle portion, and merged with the conjunctiva at its base. (Dorland, 27th ed)
A strong ligament of the knee that originates from the posteromedial portion of the lateral condyle of the femur, passes anteriorly and inferiorly between the condyles, and attaches to the depression in front of the intercondylar eminence of the tibia.
Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.
Fixation of the ANTERIOR CRUCIATE LIGAMENT, during surgical reconstruction, by the use of a bone-patellar tendon graft.
A band of fibrous tissue that attaches the apex of the PATELLA to the lower part of the tubercle of the TIBIA. The ligament is actually the caudal continuation of the common tendon of the QUADRICEPS FEMORIS. The patella is embedded in that tendon. As such, the patellar ligament can be thought of as connecting the quadriceps femoris tendon to the tibia, and therefore it is sometimes called the patellar tendon.
Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.
Operative immobilization or ankylosis of two or more vertebrae by fusion of the vertebral bodies with a short bone graft or often with diskectomy or laminectomy. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p236; Dorland, 28th ed)
Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.
Rebuilding of the ANTERIOR CRUCIATE LIGAMENT to restore functional stability of the knee. AUTOGRAFTING or ALLOGRAFTING of tissues is often used.
The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.
Injuries to the knee or the knee joint.
The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball.
The bone of the lower leg lateral to and smaller than the tibia. In proportion to its length, it is the most slender of the long bones.
Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.
Techniques for the removal of subpopulations of cells (usually residual tumor cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic BONE MARROW TRANSPLANTATION.
Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Endoscopic examination, therapy and surgery of the joint.
The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
The body location or part from which tissue is taken for TRANSPLANTATION.
The flat, triangular bone situated at the anterior part of the KNEE.
Procedures used to treat and correct deformities, diseases, and injuries to the MUSCULOSKELETAL SYSTEM, its articulations, and associated structures.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.
Cartilage of the EAR AURICLE and the EXTERNAL EAR CANAL.
The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).
Surgical procedure by which a tendon is incised at its insertion and placed at an anatomical site distant from the original insertion. The tendon remains attached at the point of origin and takes over the function of a muscle inactivated by trauma or disease.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.
Lack of stability of a joint or joint prosthesis. Factors involved are intra-articular disease and integrity of extra-articular structures such as joint capsule, ligaments, and muscles.
Tissues, cells, or organs transplanted between genetically different individuals of the same species.
A type of osteochondritis in which articular cartilage and associated bone becomes partially or totally detached to form joint loose bodies. Affects mainly the knee, ankle, and elbow joints.
The longest and largest bone of the skeleton, it is situated between the hip and the knee.
A fracture in which union fails to occur, the ends of the bone becoming rounded and eburnated, and a false joint occurs. (Stedman, 25th ed)
The second longest bone of the skeleton. It is located on the medial side of the lower leg, articulating with the FIBULA laterally, the TALUS distally, and the FEMUR proximally.
VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.
An annular transitional zone, approximately 1 mm wide, between the cornea and the bulbar conjunctiva and sclera. It is highly vascular and is involved in the metabolism of the cornea. It is ophthalmologically significant in that it appears on the outer surface of the eyeball as a slight furrow, marking the line between the clear cornea and the sclera. (Dictionary of Visual Science, 3d ed)
A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.
Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.
An absorbable suture material used also as ligating clips, as pins for internal fixation of broken bones, and as ligament reinforcement for surgically managed ligament injuries. Its promising characteristics are elasticity, complete biodegradability, and lack of side effects such as infections.
Restoration of an organ or other structure to its original site.
Forcible or traumatic tear or break of an organ or other soft part of the body.
A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.
A carpal bone located between the CAPITATE BONE and the TRIQUETRUM BONE. The hamate has a prominent process that projects anteriorly.
Procedures for enhancing and directing tissue repair and renewal processes, such as BONE REGENERATION; NERVE REGENERATION; etc. They involve surgically implanting growth conducive tracks or conduits (TISSUE SCAFFOLDING) at the damaged site to stimulate and control the location of cell repopulation. The tracks or conduits are made from synthetic and/or natural materials and may include support cells and induction factors for CELL GROWTH PROCESSES; or CELL MIGRATION.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.
Transplantation of tissue typical of one area to a different recipient site. The tissue may be autologous, heterologous, or homologous.
Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.
Surgery performed on the external, middle, or internal ear.
The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.
Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
Devices used to hold tissue structures together for repair, reconstruction or to close wounds. They may consist of adsorbable or non-adsorbable, natural or synthetic materials. They include tissue adhesives, skin tape, sutures, buttons, staples, clips, screws, etc., each designed to conform to various tissue geometries.
The process by which a tissue or aggregate of cells is kept alive outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
The physiological restoration of bone tissue and function after a fracture. It includes BONY CALLUS formation and normal replacement of bone tissue.
The process of bone formation. Histogenesis of bone including ossification.
Thin outer membrane that surrounds a bone. It contains CONNECTIVE TISSUE, CAPILLARIES, nerves, and a number of cell types.
Restoration of integrity to traumatized tissue.
Union of the fragments of a fractured bone in a faulty or abnormal position. If two bones parallel to one another unite by osseous tissue, the result is a crossunion. (From Manual of Orthopaedic Terminology, 4th ed)
The innermost membranous sac that surrounds and protects the developing embryo which is bathed in the AMNIOTIC FLUID. Amnion cells are secretory EPITHELIAL CELLS and contribute to the amniotic fluid.
Internal devices used in osteosynthesis to hold the position of the fracture in proper alignment. By applying the principles of biomedical engineering, the surgeon uses metal plates, nails, rods, etc., for the correction of skeletal defects.
A type of CARTILAGE characterized by a homogenous amorphous matrix containing predominately TYPE II COLLAGEN and ground substance. Hyaline cartilage is found in ARTICULAR CARTILAGE; COSTAL CARTILAGE; LARYNGEAL CARTILAGES; and the NASAL SEPTUM.
The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor.
The inner and longer bone of the FOREARM.
Elements of limited time intervals, contributing to particular results or situations.
The return of a sign, symptom, or disease after a remission.
Fractures of the larger bone of the forearm.
Surgical reconstruction of a joint to relieve pain or restore motion.
A type II keratin that is found associated with the KERATIN-12 in the CORNEA and is regarded as a marker for corneal-type epithelial differentiation. Mutations in the gene for keratin-3 have been associated with MEESMANN CORNEAL EPITHELIAL DYSTROPHY.
A followup operation to examine the outcome of the previous surgery and other treatments, such as chemotherapy or radiation therapy.
Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)
Specialized devices used in ORTHOPEDIC SURGERY to repair bone fractures.
Human or animal tissue used as temporary wound coverings.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
Renewal or physiological repair of damaged nerve tissue.
A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation.
Injury to any part of the eye by extreme heat, chemical agents, or ultraviolet radiation.
A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.
Tumors or cancer located in bone tissue or specific BONES.
The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.
Removal of mineral constituents or salts from bone or bone tissue. Demineralization is used as a method of studying bone strength and bone chemistry.
Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.
Partial or total replacement of the CORNEA from one human or animal to another.
Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis.
Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Carbodiimide cross-linking reagent.
Surgery performed on the heart or blood vessels.
Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).
Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.
Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Devices which are used in the treatment of orthopedic injuries and diseases.
Pathological processes consisting of the union of the opposing surfaces of a wound.
A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into OSTEOBLASTS.
Breaks in CARTILAGE.
Surgical insertion of synthetic material to repair injured or diseased heart valves.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
In horses, cattle, and other quadrupeds, the joint between the femur and the tibia, corresponding to the human knee.
The outer part of the hearing system of the body. It includes the shell-like EAR AURICLE which collects sound, and the EXTERNAL EAR CANAL, the TYMPANIC MEMBRANE, and the EXTERNAL EAR CARTILAGES.
Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)
The shaft of long bones.
The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed)
Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Transference of tissue within an individual, between individuals of the same species, or between individuals of different species.
The procedure of removing TISSUES, organs, or specimens from DONORS for reuse, such as TRANSPLANTATION.
Excision, in part or whole, of an INTERVERTEBRAL DISC. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.
The first seven VERTEBRAE of the SPINAL COLUMN, which correspond to the VERTEBRAE of the NECK.
The surgical cutting of a bone. (Dorland, 28th ed)
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Implantable fracture fixation devices attached to bone fragments with screws to bridge the fracture gap and shield the fracture site from stress as bone heals. (UMDNS, 1999)
The release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell transplantation. Hematopoietic growth factors or chemotherapeutic agents often are used to stimulate the mobilization.
Forward displacement of a superior vertebral body over the vertebral body below.
Organs, tissues, or cells taken from the body for grafting into another area of the same body or into another individual.
A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)
The bony deposit formed between and around the broken ends of BONE FRACTURES during normal healing.
The articulation between a metatarsal bone (METATARSAL BONES) and a phalanx.
Irradiation of the whole body with ionizing or non-ionizing radiation. It is applicable to humans or animals but not to microorganisms.
An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.
Bones that constitute each half of the pelvic girdle in VERTEBRATES, formed by fusion of the ILIUM; ISCHIUM; and PUBIC BONE.
The portion of the leg in humans and other animals found between the HIP and KNEE.
Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.
Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.
Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.
An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.
The physical state of supporting an applied load. This often refers to the weight-bearing bones or joints that support the body's weight, especially those in the spine, hip, knee, and foot.
A hinge joint connecting the FOREARM to the ARM.
An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.
The outer shorter of the two bones of the FOREARM, lying parallel to the ULNA and partially revolving around it.
Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.
A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)
Preparative treatment of transplant recipient with various conditioning regimens including radiation, immune sera, chemotherapy, and/or immunosuppressive agents, prior to transplantation. Transplantation conditioning is very common before bone marrow transplantation.
A strong ligament of the knee that originates from the anterolateral surface of the medial condyle of the femur, passes posteriorly and inferiorly between the condyles, and attaches to the posterior intercondylar area of the tibia.
Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.
A protective layer of firm, flexible cartilage over the articulating ends of bones. It provides a smooth surface for joint movement, protecting the ends of long bones from wear at points of contact.
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
The hemispheric articular surface at the upper extremity of the thigh bone. (Stedman, 26th ed)
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)
The interarticular fibrocartilages of the superior surface of the tibia.
Liquids transforming into solids by the removal of heat.
The destroying of all forms of life, especially microorganisms, by heat, chemical, or other means.
Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.
The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)
Fractures of the femur.
Rods of bone, metal, or other material used for fixation of the fragments or ends of fractured bones.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Surgery performed on the heart.
A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)
Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
The part of the pelvis that comprises the pelvic socket where the head of FEMUR joins to form HIP JOINT (acetabulofemoral joint).
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Glycoproteins found on immature hematopoietic cells and endothelial cells. They are the only molecules to date whose expression within the blood system is restricted to a small number of progenitor cells in the bone marrow.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.
The condition of an anatomical structure's being dilated beyond normal dimensions.
Congenital dislocation of the hip generally includes subluxation of the femoral head, acetabular dysplasia, and complete dislocation of the femoral head from the true acetabulum. This condition occurs in approximately 1 in 1000 live births and is more common in females than in males.
Injuries to the PERIPHERAL NERVES.
Progenitor cells from which all blood cells derive.
Therapeutic act or process that initiates a response to a complete or partial remission level.
Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
A fibrous cord that connects the muscles in the back of the calf to the HEEL BONE.
Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.
A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.
Diseases of the cornea.
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
The use of internal devices (metal plates, nails, rods, etc.) to hold the position of a fracture in proper alignment.
The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.

Allografts with autogenous platelet-rich plasma for tibial defect reconstruction: a rabbit study. (1/24)

PURPOSE: To evaluate the effect of autogenous platelet-rich plasma (PRP) for fresh-frozen allografts in tibial defect reconstruction in rabbits. METHODS: 40 adult New Zealand white rabbits underwent tibial defect reconstruction with autografts (n=12), allografts without PRP (n=12), or allografts with PRP (n=12) and were observed for 12, 16, and 24 weeks (4 for each period). Tibias of the remaining 4 rabbits were used as donor allografts, and the remaining allografts were procured from recipient rabbits. A 1.5- cm cortical segment of the tibia was osteotomised, and then fixed with a 9-hole mini-compression plate and 2 cerclage wires. Allografts were stripped off the periosteum and soft tissues and medullary contents, and then stored in a freezer at -80 masculineC. All allografts were deep frozen for at least 4 weeks before transplantation. 7 ml of whole blood was drawn to prepare 1 ml of PRP. The PRP was then mixed with 1.0 ml of human thrombin to form a platelet gel. The PRP gel was then packed into the medullary canal of the allograft and applied on the cortical surface before tibial defect reconstruction. Rabbits were sacrificed at 12, 16, and 24 weeks. The specimens were assessed for bone union at host-graft junctions and for bone resorption, new bone formation, callus encasement, and viable osteocyte counts. RESULTS: There were 4 specimens in each group at each observation period. Osteoid bridging the gap at host-graft junctions was noted in all specimens in the autograft and allograft-with-PRP groups at week 12 and in the allograft-without-PRP group at week 24. Bone union in allografts without PRP was delayed. All indices for biological incorporation (resorption index, new bone formation index, callus encasement index, and viable osteocyte count) were significantly greater in the autograft than allograft-without-PRP groups, except for the resorption index at week 24, whereas the differences were not significant between the autograft and allograft-with-PRP groups. The differences between the 2 allograft groups were usually not significant, except for the resorption index. CONCLUSION: PRP-augmented allografts behaved similarly to autografts for tibial defect reconstruction in rabbits. PRP increased bone union and bone resorption.  (+info)

Distal fibular lengthening after premature growth arrest: a case report. (2/24)

Post-traumatic premature closure of the distal fibular growth plate is a rare entity leading to shortening of the lateral malleolus. We report on a 14-year old boy who presented with a 4-year history of worsening, diffuse discomfort and swelling of his left ankle, as well as fibular shortening and talar malreduction. He had sustained a distal tibial fracture 4 years earlier and had been treated with closed reduction. He reported instability of the ankle and difficulty with running. There was 1-cm shortening of the left fibula, 1-cm shortening of the proximal fibula, and slight widening of the medial clear space. Both tibial and fibular growth plates were already closed and the left ankle joint space was slightly narrowed. He was treated with late fibular lengthening and autogenous iliac crest tricortical bone grafting and achieved anatomic restoration of the distal tibiofibular relationship. At one-year follow-up, the ankle-hindfoot score had improved from 69 to 100.  (+info)

A pilot study of tandem high-dose chemotherapy with stem cell rescue as consolidation for high-risk neuroblastoma: Children's Oncology Group study ANBL00P1. (3/24)

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Combination of orthodontic movement and periodontal therapy for full root coverage in a Miller class III recession: a case report with 12 years of follow-up. (4/24)

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Clinical results of auto-iliac cancellous bone grafts combined with implantation of autologous bone marrow cells for osteonecrosis of the femoral head: a minimum 5-year follow-up. (5/24)

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Renal autotransplant in patients with complex hilar renal artery aneurysms. (6/24)

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Esthetic-functional recovery of permanent posterior tooth using autogenous biological restoration. (7/24)

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Verification of the feasibility of autogenous testis implant in omentum and abdominal wall in mice. (8/24)

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Tetrahydrozoline is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). Tetrahydrozoline nasal (for the nose) is for temporary relief of nasal congestion (stuffy nose) caused by allergies or the common cold. Tetrahydrozoline nasal may also be...
Tetrahydrozoline is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). Tetrahydrozoline nasal (for the nose) is for temporary relief of nasal congestion (stuffy nose) caused by allergies or the common cold. Tetrahydrozoline nasal may also be...
Tetrahydrozoline is a vasoconstrictor. It works by narrowing swollen blood vessels in the eyes to reduce eye redness. Tetrahydrozoline ophthalmic (for the eyes) is for temporary relief of minor eye redness, swelling, or draining caused by minor irritants. Tetrahydrozoline ophthalmic may also be used for purposes not...
Tetrahydrozoline is a vasoconstrictor. It works by narrowing swollen blood vessels in the eyes to reduce eye redness. Tetrahydrozoline ophthalmic (for the eyes) is for temporary relief of minor eye redness, swelling, or draining caused by minor irritants. Tetrahydrozoline ophthalmic may also be used for purposes not...
Literatur:. 1 Michele Cavo, et al. Intensification Therapy with Bortezomib-Melphalan-Prednison Versus Autologous Stem Cell Transplantation for Newly Diagnosed Multiple Myeloma: An Intergroup, Multicenter, Phase III Study of the European Myeloma Network (EMN02/HO95 MM Trial) Oral Abstract 6739; Session 731; ASH 2016 (https://ash.confex.com/ash/2016/webprogram/ Paper91284.html). 2 Pieter Sonneveld, et al. Consolidation Followed By Maintenance Therapy Versus Maintenance Alone in Newly Diagnosed, Transplant Eligible Patients with Multiple Myeloma (MM): A Randomized Phase 3 Study of the European Myeloma Network (EMN02/HO95 MM Trial) Oral Abstract 242; Session 653; ASH 2016 (https://ash.confex.com/ash/2016/webprogram/Paper91988.html). 3 Thierry Facon ,et al. Final Analysis of Overall Survival from the First Trial. Oral Abstract 241; Session 653; ASH 2016 (https://ash.confex.com/ash/2016/webprogram/Paper91328.html). 4 Asher A. Chanan-Khan, et al. Daratumumab, Bortezomib and Dexamethasone Versus ...
High-dose therapy followed by autologous transplantation has improved survival in MM, however all patients eventually relapse, indicating the need for consolidation. Activation of idiotype-specific T cells by vaccination with autologous tumorprotein-loaded dendritic cells has been demonstrated. So-called Vaccibodies (consisting of two scFv (single chain Fragment variable) specific for surface molecules on APC (MHCII, CD40) linked to two exchangeable scFv from the mouse M315 myeloma protein and a Cγ3 dimerizing domain) elicit anti-Id antibodies in mice even in the absence of adjuvant, and stimulate Id-specific CD4+ T cells in vitro ...
In the abnormal myeloma cells several specific translocations have been described that facilitate cell survival. t(4;14) involves expression of the Fibroblast Growth Factor Receptor 3 (FGFR3) in most cases, activation of which initiates intra cellular signalling and activation of anti-apoptotic genes in the myeloma cells. t(11;14) activates the cyclin D1 gene, which promotes the initiation of the cell cycle, enabling myeloma cells to divide and proliferate. Loss of tumour suppressor genes such as Retinoblastoma-1 gene through deletion of chromosome 13q, ongoing p53 mutations and activation of the proto-oncogenes c-Maf through the t(14;16) and C-myc, as well as activation of the anti-apoptosis genes bcl-2 and Mcl1 all result in improved survival advantages for abnormal myeloma cells. ...
Physician reviewed tetrahydrozoline ophthalmic patient information - includes tetrahydrozoline ophthalmic description, dosage and directions.
The primary objective for this study is to evaluate the use of immunosuppressive drugs such as Campath -1H or h-ATG, fludarabine, and sirolimus in conjunction with a novel busulfan-based conditioning regimen with or without the addition of radia ...
The primary objective for this study is to evaluate the use of immunosuppressive drugs such as Campath -1H or h-ATG, fludarabine, and sirolimus in conjunction with a novel busulfan-based conditioning regimen with or without the addition of radia ...
FML - Prescribed for Eye Redness/Itching, Eyelash Hypotrichosis, Eye Redness. tetrahydrozoline ophthalmic - Prescribed for Eye Redness.
Multiple myeloma management has undergone profound changes in the past thanks to advances in our understanding of the disease biology and improvements in treatment and supportive care approaches. This article presents recommendations of the European Myeloma Network for newly diagnosed patients based on the GRADE system for level of evidence. All patients with symptomatic disease should undergo risk stratification to classify patients for International Staging System stage (level of evidence: 1A) and for cytogenetically defined high-versus standard-risk groups (2B). Novel-agent-based induction and up-front autologous stem cell transplantation in medically fit patients remains the standard of care (1A). Induction therapy should include a triple combination of bortezomib, with either adriamycin or thalidomide and dexamethasone (1A), or with cyclophosphamide and dexamethasone (2B). Currently, allogeneic stem cell transplantation may be considered for young patients with high-risk disease and ...
Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Manual outside of North America.. ...
ABSTRACT Introduction. Combinations of fibrous materials with therapeutic agents as a drug delivery system are currently studied. A new direction has appeared in reconstructive surgery - tissue engineering, which aims to restore biological functions, i.e. tissue regeneration, not only to replace it with synthetic material.. The objective of the study was to evaluate the antibiotic-sorbing ability of the three-dimensional non-woven matrices we created for reconstructing bone defects, made of polycaprolactone, and the possibility of releasing the impregnated antibiotic from the matrix material.. Materials and methods. The study was conducted in the Department of Surgical Dentistry of Ivano-Frankivsk National Medical University, Ukraine, between September 12, 2019 - October 3, 2019. We used samples of three-dimensional micro-fibrous non-woven matrix for the defects reconstruction of the bone tissue made of polycaprolactone according to the developed technique. Collagen fragments were used as ...
The OCT scan shows a neurosensorial detachment and a bilaminar structure schisis-like between external and internal retinal layers associated to an optic disc pit, in a 10-year-old male patient. He reported loss of vision starting 3 weeks ago ...
The best 8 synonyms for autograft, including: allograft, xenograft, autoplasty, excisional, arthroscopic, orthotopic, jejunal, incisional and more... Find another word for autograft at YourDictionary.
Looking for online definition of tetrahydrozoline hydrochloride in the Medical Dictionary? tetrahydrozoline hydrochloride explanation free. What is tetrahydrozoline hydrochloride? Meaning of tetrahydrozoline hydrochloride medical term. What does tetrahydrozoline hydrochloride mean?
Purpose Mucins are vital to keep the ocular surface hydrated. Genes encoding for mucins contain a glucocorticoid response element. The purpose of this study was to evaluate the effect of fluorometholone, a glucocorticoid receptor agonist used in the management of dry eye, on the gene expression of conjunctival and corneal epithelial cell mucins. Methods Stratified cultures of human conjunctival and corneal epithelial cells were exposed to 25, 50 and 100 nM of fluorometholone alone or in presence of mifepristone, a glucocorticoid receptor antagonist. The mRNA was isolated from the cells and reverse transcribed to cDNA. The cDNA was used for quantification of gene expression of mucin (MUC) 1, 4, 16 and 19 using real‐time PCR. Results Fluorometholone caused a dose‐ and time‐dependent increase in the gene expression of MUC1, MUC4, MUC16 and MUC19 in the conjunctival as well as corneal epithelial cells. Mifepristone, a glucocorticoid receptor antagonist, inhibited fluorometholone‐mediated increase
OBJECTIVES. This study was performed at the Clinic of Surgery and Ophthalmology of the Faculty of Veterinary Sciences between years of 1998 and 2001.. Deep melting and uncomplicated corneal ulcers are common in dogs. Only medical treatment is not effective in the therapy. There are numerous methods for the surgical management of corneal ulcers. We wanted to answer the next questions:. 1. If the free island graft method effective enough in the healing of deep ulcers?. 2. If the free graft remains vital after transplantation?. 3. Is the graft able to integrate into the tissue of the cornea?. 4. If the vision is affected after the complete healing?. MATERIALS. Fifty canine eyes (of 49 dogs; 42 pure breed dogs, 7 mixed) with deep corneal ulcers were operated with the free conjunctival graft transplantation method during the examination period. Detailed physical eye examination were performed regularly in each dogs prior and after to surgery with slit lamp biomicroscope, applanation tonometer and ...
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MURINE PLUS REDNESS RELIEF (Polyvinyl alcohol,Povidone,Tetrahydrozoline) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
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Purpose : In a recent clinical trial (Pinto-Fraga, Ophthalmology 2015) we concluded that topical 0.1% fluorometholone therapy reduced ocular signs in dry-eye (DE) patients and prevented exacerbation caused by exposure to desiccating stress (DS). We now identify severity, activity (i.e. response to DS) and therapeutic tear biomarkers (tBM) in these patients using linear mixed effect statistical models. Methods : 41 DE patients were recruited (visit 1, V1) and randomized to receive either topical 0.1% fluorometholone or its vehicle polyvinyl alcohol, 4 times daily for 21 days (V2). Immediately after, patients were exposed to DS in a controlled environment laboratory for 2h (V3) which increases DE activity as previously reported (Lopez-Miguel, Am J Ophthalmol 2014). Clinical evaluation and tear collection were performed at each visit. A panel of 18 potential tBM (EGF, IFNγ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-13, IL-1RA, IL-17A, IP-10, RANTES, TNFα, MIP-1α, MMP-9, MCP-1) was ...
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Fingerprint Dive into the research topics of Old Age Lower Lip Cancer Defects Reconstruction by Abbe-Estlander Flap. Together they form a unique fingerprint. ...
Coarctation of the aorta. Sem Thor Card Surg. Coarctation of the aorta and aortic arch interruption. Cardiac Surgery, 2nd ed. New York: Churchill-Livingstone; Role of Extended aortoplasty related to the definition of coarctation of the aorta. Ann Thorac Surg. Coarctation of the aorta and interrupted aortic arch. Baltimore: Williams and Wilkins; Beekman RH. Moss and Adams. W Baltimore: Williams and Wilkins; Naranjo A. World Medical Association.. Stark J. En Stark J, de Leval M, eds. Surgery for congenital heart defects, 2nd ed. Philadelphia: Saunders; Prediction of recurrent coarctation by early postopera-tive blood pressure gradient. J Thorac Cardiovasc Surg. Am J Cardiol. Aortoplasty the operation of choice for infant aortic co-arctation?. Extended resection and end-to-end anastomosis for aortic coarctation in infants: results of a tailored surgical approach. Percutaneous interventions on se-vere coarctation of the aorta: a year experience. Pe-diatr Cardiol. Severe aortic coarctation in infants ...
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Get quotes fast and Choose from 2 clinic(s) offering Pterygium Excision with Graft treatment in Spain Get quotes fast & choose the best with phone numbers, reviews, prices, maps and pictures. | Page 0
PURPOSE: To identify the incidence, presenting features, treatment, and clinical course of optic disc pit maculopathy (ODPM) in the United Kingdom (UK). DESIGN: A 2-year nationwide prospective population-based study. SUBJECTS: All new incident cases of ODPM presenting to UK ophthalmologists using the British Ophthalmic Surveillance Unit monthly reporting system. METHODS: All reporting ophthalmologists were sent an initial questionnaire requesting data on previous medical and ophthalmic history, presentation details, investigation findings, and management. A further questionnaire was sent at 12 months post diagnosis to ascertain further outcome data. MAIN OUTCOME MEASURES: Visual acuity at initial presentation, at 1 year, and after any intervention. Foveal involvement and optical coherence tomography (OCT) findings, including retinal layers affected, and the location and size of the optic disc pit. Management, including observation, vitrectomy, and associated procedures. RESULTS: There were 74 ...
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Visine Eye Drops is used for blockage of nasal passages, ear inflammation, irritation in the eye, excessive ingrowth of blood vessels in cornea of eye and other conditions. Visine Eye Drops contains the following active ingredients: Tetrahydrozoline Hcl.
Zhou Z, Nath R, Cerny J, Wang HL, Zhang MJ, Abdel-Azim H, Agrawal V, Ahmed G, Al-Homsi AS, Aljurf M, Alkhateeb HB, Assal A, Bacher U, Bajel A, Bashir Q, Battiwalla M, Bhatt VR, Byrne M, Cahn JY, Cairo M, Choe H, Copelan E, Cutler C, Damlaj MB, DeFilipp Z, De Lima M, Diaz MA, Farhadfar N, Foran J, Freytes CO, Gerds AT, Gergis U, Grunwald MR, Gul Z, Hamadani M, Hashmi S, Hertzberg M, Hildebrandt GC, Hossain N, Inamoto Y, Isola L, Jain T, Kamble RT, Khan MW, Kharfan-Dabaja MA, Kebriaei P, Kekre N, Khera N, Lazarus HM, Liesveld JL, Litzow M, Liu H, Marks DI, Martino R, Mathews V, Mishra A, Murthy HS, Nagler A, Nakamura R, Nathan S, Nishihori T, Olin R, Olsson RF, Palmisiano N, Patel SS, Patnaik MM, Pawarode A, Perales MA, Politikos I, Popat U, Rizzieri D, Sandmaier BM, Savani BN, Seo S, Shah NN, Uy GL, Valcárcel D, Verdonck LF, Waller EK, Wang Y, Weisdorf D, Wirk B, Wong E, Yared JA, Saber W. Reduced intensity conditioning for acute myeloid leukemia using melphalan- vs busulfan-based regimens: a ...
The ultrasonic scissors work better than other modalities for this dissection. In chronic cases of subepithelial infiltrates, judicious use of a mild topical cor- ticosteroid such as fluorometholone 0. Freeze-dry the Buy Scifil California. 2872 Sertaconazole nitrate.
VPS, which stands for virtual private server, is a happy middle ground between the casual dating of shared hosting and the commitment of a dedicated server. The server is divided into virtual machines, which act as independent dedicated servers. VPS customers still share a server, but they each have much larger portions and greater control than those with a shared hosting plan.. Because you can add or remove additional computing resources as needed, VPS hosting plans are akin to dating around - you might have a relatively serious relationship with your main server squeeze, but that doesnt mean you cant have someone else on standby for when you have an itch you need scratching.. Our favorite VPS hosts usually include storage with high-speed SSDs, or solid-state drives, along with managed services for software updates and patches. Depending on your comfort level with the technical side of things, youll want to look for a free cPanel license or full root access. You will also see top VPS hosts ...
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Donor mobilization : Donor will be mobilized with G-CSF (Granocyte) sub-cutaneous 10 µg/kg/day during 5 to 6 days. Hematopoïetic Stem Ce
HOUSTON {AP}— A New York woman who traveled to Houston last year for a rare surgery in which her heart was removed from her body and three tumors were cut out of the organ has died of cancer.
TY - JOUR. T1 - Therapeutic effects of concurrent autologous bone marrow cell infusion and metabolic intervention in ischemia-induced angiogenesis in the hypercholesterolemic mouse hindlimb. AU - de Nigris, Filomena. AU - Williams-Ignarro, Sharon. AU - Sica, Vincenzo. AU - DArmiento, Francesco P.. AU - Lerman, Lilach O.. AU - Byrns, Russell E.. AU - Sica, Giacomo. AU - Fiorito, Carmela. AU - Ignarro, Louis J.. AU - Napoli, Claudio. PY - 2007/4/25. Y1 - 2007/4/25. N2 - Lower-limb ischemia is a major health problem especially when associated to hypercholesterolemia. Because of the absence of effective treatment in the advanced stages of the disease, amputation is undertaken to alleviate unbearable symptoms. Since tissue ischemia and hypercholesterolemia are associated with an overwhelming generation of oxygen radicals, metabolic intervention with antioxidants and l-arginine can induce beneficial effects beyond those achieved by a novel therapeutic approach represented by the use of autologous ...
and corticosteroid eye drops such as dexamethasone (Maxidex), fluorometholone (FML), hydrocortisone (in Cortisporin), loteprednol (Alrex, Lotemax), medrysone ...
TY - JOUR. T1 - Optimizing Bone Defect Reconstruction - Balanced Cable Transport with Circular External Fixation. AU - Quinnan, Stephen. AU - Lawrie, Charles. PY - 2017/10/1. Y1 - 2017/10/1. N2 - Distraction osteogenesis has proven effective in the management of tibial bone loss from severe trauma and infection. Unfortunately, pain and scarring from wires and half pins dragging through the skin and the required prolonged time in the external fixator make treatment difficult. Cable bone transport has been shown to improve cosmesis and decrease pain during transport. However, the published methods have limitations in that they have poor control of transport segment alignment, do not allow for lengthening of the limb, and do not permit weight bearing during the treatment process. We describe a novel method of cable bone transport that addresses each of these limitations with excellent control of alignment including the transport segment, easy conversion to allow limb lengthening, and full weight ...
A pterygium is a wedge-shaped piece of abnormal tissue that grows out of the cornea. Whether or not surgical removal of a pterygium is recommended depends on its size and extent, as well as its tendency for recurrent inflammation. If a pterygium is small but becomes intermittently inflamed, the ophthalmologist may recommend the use of a nonsteroidal or a mild steroid eye drop when the inflammation develops. Removal is typically recommended if the pterygium grows far enough onto the cornea to impair vision, if it causes chronic inflammation and irritation, or if it interferes with contact lens wear.. Surgical removal of a pterygium is an outpatient procedure that takes less than an hour to perform. The risk of recurrence of the pterygium after surgery can be reduced with the use of a conjunctival graft taken from under the upper eyelid that is placed over the site where the pterygium was located. The graft may be secured with sutures or with human fibrin tissue glue (sutureless pterygium ...
Am old enough to understand the difference between the Bay of Pigs - and roasting a pig at a epicurian feast. Been thru the hippy, yippie and yuppie years - always remaining who I am. Very much believe in Sing your own song - weave your own tapestry Am young enough to still know the thrill of new discoveries, the beauty of the evening, to celebrate the joy of another tommorow. Survived these many decades with a severe medical problems. Sorting out the maze of now having two lymphomas and all their nasty little companions, but I continue. Besides, being a simple iconoclastic eclectic, have been called many things. An incurable romanticist - with a strong touch of reality. Thinker, intellectual (God, how I hate that term) - been told I am a lion with the heart of the poet. Know how to wage war and conquer my foes - but would rather be known as one who brings hope and life. To bring hope into anothers life is the ultimate of joys. Life should be about bringing hope, peace, vision... a sense of ...
We report a case of ocular chronic GVHD diagnosed and clasified as mild/moderate with GVHD consensus group test and severity index. Before evaluation and initial good response to treatment, the patient appear at urgency room with poor clinic manifestations. But at slit lamp examination it reveal a corneal perforation on right eye that needed conjunctival graft. We closely follow up the patient and we found a corneal melting on his left eye a month later that needed contact lens, systemic and topical treatment ...
This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the tube to your eye, fingertips, or other surface. Squeeze the end of the tube and apply a thin layer of the ointment to the inside of the lower eyelid. Close the eye gently to spread the ointment. Your vision may blur for a few minutes. Use your doses at regular intervals. Do not use more often than directed. Do not stop using except on the advice of your doctor or health care professional.. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this medicine may be prescribed for children as young as 2 years, precautions do apply.. ...
Looking for online definition of autograft in the Medical Dictionary? autograft explanation free. What is autograft? Meaning of autograft medical term. What does autograft mean?
My doc excised two pterygium from the same eye (one located toward the inner part nasal and one located toward the outer part tempor
You remember how the plan was to have an autograft?. Forget that.. It seems Im not much good at getting my stem cells going, as the bone marrow harvest the other day didnt provide nearly enough for the autograft… Its unlikely that further harvests would suddenly garner big results, and without enough stem cells for the rescue I cant have the high-dose chemotherapy and radiotherapy, so the autograft is no longer a possibility. Naturally this is a bit frustrating, as Id got my mind set on it and was looking forward to potentially finishing my treatment in the next couple of months and being back to full strength by, say, September.. Instead, Ill now be having the long-term chemotherapy option, which of course has its advantages. Although Ill still be having some radiotherapy, itll just be cranial this time, so hopefully the side effects will be less. The treatment is less intense than the autograft, and there will not be the 5-10% risk of picking up an infection that would prove fatal. ...
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We welcome members of IOSS and other non-members to submit abstracts to cover the research data of pathogenesis or a comprehensive study (see Abstract Form). The selection criteria are based on the subjects to be covered (see above). We also solicit video presentation (see above Critical Appraisals), each video clip for 1-2 min to cover a key step of the above three major procedures. Taking conjunctival autograft as an example, the key steps include anesthesia, fixation, head removal, removal of subconjunctival tissue, muscle isolation, preparation of graft, suturing technique, etc. For video presentation, the abstract may mention as many key steps as one would like for one or three procedures. Naturally, we also welcome new surgical procedures.. Also see Web site www.ioss.org for more information about the meeting including how to become a member of IOSS, registration and submission of abstract for this meeting.. :::::::::::::::::::::::::::::::: Dear Colleagues: It is exciting for me to ...
Autograft[edit]. An accessory hamstring or part of the patellar ligament are the most common donor tissues used in autografts. ... folded and used as an autograft (1). It appears through the remnant of the injured original ACL (3). The autograft then courses ... Autografts (employing bone or tissue harvested from the patient's body). *Allografts (using bone or tissue from another body, ... Hamstring autografts are made with the semitendinosus tendon, either alone or accompanied by the gracilis tendon for a stronger ...
"Nerve Autografts." Strategies in Regenerative Medicine: Integrating Biology with Materials Design. New York: Springer, 2009. ...
AutograftEdit. Main article: Autotransplantation. Autografts are the transplant of tissue to the same person. Sometimes this is ... 1869: First skin autograft-transplantation by Carl Bunger, who documented the first modern successful skin graft on a person. ... Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently ... Skin, including face replant (autograft) and face transplant (extremely rare). *Islets of Langerhans (pancreas islet cells) ( ...
This can either be from the person (autograft) or from a donor (allograft). People undergoing a joint transplant (osteochondral ... "Osteochondral Autograft & Allograft". Washington University Orthopedics. Retrieved 2020-01-26. Favinger, Jennifer L.; Ha, Alice ... Autologous articular cartilage transfer from a non-weight-bearing area to the damaged area, called osteochondral autograft ...
Hardy, M. H., Fraser, A. S. and Short, B. F. (1952). Spread of Pigment in Sheep Skin Autografts. Nature. 170(4333): 849. Hardy ...
"Intraoral paratrichosis after autograft". Cir y Cir. 83 (4): 309-11. doi:10.1016/j.circir.2015.05.017. PMID 26118782. Reamy, BV ...
... autografting and homografting techniques; sheet method and postage stamp method of grafting (21 min; color). PMF 5321 (1959) - ...
Orentreich, Norman (1959). "Autografts in Alopecia and Other Selected Dermatologic Conditions". Annals of the New York Academy ...
Autograft: graft taken from one part of the body of an individual and transplanted onto another site in the same individual, e. ... Autografts and isografts are usually not considered as foreign and, therefore, do not elicit rejection. Allografts and ...
Mark Ruzmetov, Karl F. Welke, Dale M. Geiss, Klay Buckley and Randall S. Fortuna (2014). "Failed Autograft After the Ross ... Yacoub modified the operation by planning remodelling of the autograft root, the Ross-Yacoub procedure, performed in carefully ... Torres, Enrique Garcia (11 July 2012). "Ross Procedure With Pulmonary Autograft Reinforcement". CTSNet. ... "The Ross-Yacoub procedure for aneurysmal autograft roots: a strategy to preserve autologous pulmonary valves". The Journal of ...
Allografts are done by creating bone grafts from a donor bone bank, while autografts are bone grafts from other bones in a ... This is accomplished through the use of Allografts and Autografts. ...
Autografts, or autologous grafts, are body tissues taken from the patient. The first successful cranioplasty using an autograft ... The use of autograft is also associated with a high rate of bone resorption. Synthetic materials are used for paediatric ... Succeeding operations involved autografts taken from different parts of the patient's body, such as the tibia (leg bone), ... It is less commonly used than autografts due to its brittle nature, high infection rate, and poor ability to integrate with the ...
... living-donor and autograft) Blood transfusion/Blood Parts Transfusion (living-donor and autograft) Blood vessels (autograft and ... Autografts are the transplant of tissue to the same person. Sometimes this is done with surplus tissue, tissue that can ... The first reasonable account is of the Indian surgeon Sushruta in the 2nd century BC, who used autografted skin transplantation ... Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently ...
Artificial skin can be made from autografts, allografts, and xenografts. Autografted skin comes from a patient's own skin, ...
Pulmonary autograft replacement of the aortic valve is the operation of choice in infants and children, but its use in adults ... The results of the pulmonary autograft procedure are likely to be superior with the use of fresh homograft valves. Today, ... The Ross-Yacoub procedure (or pulmonary autograft) is a cardiac surgery operation where a diseased aortic valve is replaced ... Chambers J, Somerville J, Stone S, Ross D (1997). "Pulmonary autograft procedure for aortic valve disease: long-term results of ...
Autografts are taken from the recipient. If absent or deficient of natural tissue, alternatives can be cultured sheets of ...
Kiser, J. C.; Farley, H. H.; Mueller, G. F.; Strobel, C. J.; Hitchcock, C. R. (1960). "Successful renal autografts in the dog ... "Immunologic injury induced by ex vivo perfusion of canine renal autografts". Surgery. 76 (1): 88-100. ISSN 0039-6060. PMID ...
Furthermore, autografted bones are avascular and hence are dependent on diffusion for nutrients, which affects their viability ... Currently, the standard treatment is autografting which involves obtaining the donor bone from a non-significant and easily ... Betz RR (May 2002). "Limitations of autograft and allograft: new synthetic solutions". Orthopedics. 25 (5 Suppl): s561-70. doi: ...
Currently, autograft bone harvested from the iliac crest is considered the 'gold standard' due to its superior osteogenic ... Allograft bone is a logical alternative to autograft. However, it must be rigorously processed and terminally sterilized prior ...
Higgins, RM; Richardson, AJ (1991). "Total parathyroidectomy alone or with autograft for renal hyperparathyroidism?". QJM. 79 ( ...
A pulmonary autograft, also known as the Ross procedure is where the aortic valve is removed and replaced with the patient's ... aortic homografts and pulmonary autografts. An aortic homograft is an aortic valve from a human donor, retrieved either after ...
Nakayama K, Yamamoto K, Tamiya T, Makino H, Odaka M, Ohwada M, Takahashi H (1964). "Experience With Free Autografts Of The ...
In humans, artificially made columella may be produced as autografts from cortical bone. These prostheses are used as ...
"Open Microsurgical Autograft of Adrenal Medulla to the Right Caudate Nucleus in Two Patients with Intractable Parkinson's ... "Transplantation Techniques and the Survival of Adrenal Medulla Autografts in the Primate Brain". Annals of the New York Academy ... these cells have been investigated as an intrastriatal autograft therapy for patients with Parkinson's disease. A clinical ...
The pulmonary autograft, now widely known as the Ross procedure, first performed in 1967, was the logical development of the ... More significantly, he developed the pulmonary autograft, known as the Ross procedure, for treatment of aortic valve disease. ... or pulmonary autograft for aortic valve disease. He has said that his interest had lain "particularly with the valves- ... "Replacement of aortic and mitral valves with a pulmonary autograft". Lancet. 2: 956. doi:10.1016/s0140-6736(67)90794-5. 1968: ...
March 2007). "A comparison of allografting with autografting for newly diagnosed myeloma". The New England Journal of Medicine ...
Tardy, M. Eugene; Denneny, James; Fritsch, Michael H. (1985). "The Versatile Cartilage Autograft in Reconstruction of the Nose ...
An autograft is a graft that comes from the patient) Hamstring tendon autograft Quadriceps tendon autograft Allograft (taken ... Nedeff DD, Bach BR (2001). "Arthroscopic anterior cruciate ligament reconstruction using patellar tendon autografts: a ... A typical surgery for a blown knee includes: Patellar tendon autograft ( ...
Jia ZY, Zhang C, Cao SQ, Xue CC, Liu TZ, Huang X, Xu WD (July 2017). "Comparison of artificial graft versus autograft in ... LARS ligaments demonstrate higher stability and lower morbidity rate compared to autograft in short term research and in a 9- ... Liu ZT, Zhang XL, Jiang Y, Zeng BF (February 2010). "Four-strand hamstring tendon autograft versus LARS artificial ligament for ... Currently, the LARS ligament is the most comparable to both autografts and other synthetic grafts. Complications that commonly ...
Instruments that enable the surgeon to pack additional autograft through portals in the implant after it has been implanted and ...
Ligafix 60 for ACL reconstruction with a doubled semitendinosus/gracilis autograft - soft tissue), and in degenerative or ...
An interesting case of autografting ». Whats this?. You are currently reading SurgeXperiences 112 - Call for submissions at ...
A: Autograft - Magic Stick (Chill Remix). A: 50 Cent Ft. Nate Dogg - 21 Questions. A: G-Unit - P.I.M.P (Remix) ...

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