Intentionally using oneself as a research subject.

Live attenuated vaccine trials in medically informed volunteers: a special case? (1/7)

A group of activist clinicians have offered to volunteer for clinical trials of live attenuated HIV vaccines. This has provided an important conceptual challenge to medical ethics, and to work on the development of HIV vaccines. In exploring these issues, this article highlights how the HIV field has altered the content as well as the tone of ethical discourse. The balance of expertise and authority between research subjects and triallists is profoundly changed, raising questions about the limits of voluntarism and differing perspectives on risk-benefit analysis. Care is needed to ensure that the novelty of the situation does not confuse the central ethical and scientific issues.  (+info)

The case for a new system for oversight of research on human subjects. (2/7)

The increasing emphasis on evidence-based clinical practice has thrown into sharp focus multiple deficiencies in current systems of ethical review. This paper argues that a complete overhaul of systems for ethical oversight of studies involving human subjects is now required as developments in medical, epidemiological and genetic research have outstripped existing structures for ethical supervision. It shows that many problems are now evident and concludes that sequential and piecemeal amendments to present arrangements are inadequate to address these. At their core present systems of ethical review still rely on the integrity and judgment of individual investigators. One possible alternative is to train and license research investigators, make explicit their responsibilities and have ethics committees devote much more of their time to monitoring research activity in order to detect those infringing the rules.  (+info)

Homeopathic pathogenetic trials produce specific symptoms different from placebo. (3/7)

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The unreasonable effectiveness of my self-experimentation. (4/7)

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N of 1, two contemporary arm, randomised controlled clinical trial for bilateral epicondylitis: a new study design. (5/7)

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Limits on risks for healthy volunteers in biomedical research. (6/7)

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Self-experimentation and its role in medical research. (7/7)

Although experimentation involving human volunteers has attracted intense study, the matter of self-experimentation among medical researchers has received much less attention. Many questions have been answered only in part, or have been left unanswered. How common is this practice? Is it more common among certain nationalities? What have been the predominant medical fields in which self-experimentation has occurred? How dangerous an act has this proved to be? What have been the trends over time? What is the future likely to bring?From the available literature, I identified and analyzed 465 documented instances of this practice, performed over the course of the past 2 centuries. Most instances occurred in the United States. The peak of self-experimentation occurred in the first half of the 20th century. Eight deaths were recorded. A number of the investigators enjoyed successful careers, including the receipt of Nobel Prizes. Although self-experimentation by physicians and other biological scientists appears to be in decline, the courage of those involved and the benefits to society cannot be denied.  (+info)

Autoexperimentation is a term used to describe the practice of self-administering medical treatments, drugs, or procedures on oneself. It is often performed by healthcare professionals, researchers, or individuals with medical knowledge who are seeking to test the safety and efficacy of new treatments or to gain personal experience with a particular medical condition or therapy.

Autoexperimentation can be dangerous and unethical if not conducted properly, as it may expose the individual to unnecessary risks and harm. Therefore, it is generally discouraged in the medical community unless it is done under strict guidelines and supervision, and with appropriate safeguards in place to protect the individual's health and well-being.

... autoexperimentation MeSH H01.770.644.145.500.750 - nontherapeutic human experimentation MeSH H01.770.644.145.500.875 - ...
Altman, Lawrence K. (1972) "Auto-Experimentation - An Unappreciated Tradition in Medical Science." N Engl J Med 1972; 286:346- ...
... autoexperimentation MeSH H01.770.644.145.500.750 - nontherapeutic human experimentation MeSH H01.770.644.145.500.875 - ...
Autoexperimentation.. 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM. Topical term or geographic name as entry element. Human ...
autoexperimentation Intentionally using oneself as a research subject. * idiosyncrasy State of abnormal sensitivity, of ...
Autoexperimentation *. Informed Consent: III. Consent Issues in Human Research *. The Belmont Report ...
A lifetime of auto-experimentation has made him powerful, but his vastly enhanced metabolism means he must feed constantly to ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
The latter has been known as the negative way which, by the eye of the soul directed inwardly, can still conduct auto-experimentation ...
Autoexperimentation 48. A case of double pulmonic murmur, with diastolic thrill Author(s): Hall, J. N. (Josiah Newhall), 1859- ...
Tarini BA, Goldenberg A, Singer D, Clark SJ, Butchart A, Davis MM. Not without my permission: parents willingness to permit use of newborn screening samples for research. Public Health Genomics. 2010; 13(3):125-30 ...
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AUTOEXPERIMENTATION. BLOOD BANKS. CIRCUMCISION. COMPUTER COMMUNICATION NETWORKS. CONTINUING EDUCATION. DOMESTIC VIOLENCE. ...
Autoexperimentation--ethics. Ethics, Research. Research Subjects Publication Types: Lecture. Webcast NLM Classification: W ...
Our findings suggest that, following ingestion, some infective larvae of A. caninum develop directly into adult worms in the human gut (as they do in dogs). While the percutaneous route might be the most common means of human exposure to canine hookworm larvae, leading generally to subclinical infec …
Autoexperimentation Preferred Concept UI. M0010648. Scope Note. Intentionally using oneself as a research subject.. Terms. ... Autoexperimentation Preferred Term Term UI T020564. Date02/03/1998. LexicalTag NON. ThesaurusID ... Autoexperimentation. Tree Number(s). E05.445.100. H01.770.644.145.365.100. Unique ID. D032762. RDF Unique Identifier. http://id ...
Autoexperimentation Preferred Concept UI. M0010648. Scope Note. Intentionally using oneself as a research subject.. Terms. ... Autoexperimentation Preferred Term Term UI T020564. Date02/03/1998. LexicalTag NON. ThesaurusID ... Autoexperimentation. Tree Number(s). E05.445.100. H01.770.644.145.365.100. Unique ID. D032762. RDF Unique Identifier. http://id ...
Roberts, R. D., Lizardo, M. M., Reed, D. R., Hingorani, P., Glover, J., Allen-Rhoades, W., Fan, T., Khanna, C., Sweet-Cordero, E. A., Cash, T., Bishop, M. W., Hegde, M., Sertil, A. R., Koelsche, C., Mirabello, L., Malkin, D., Sorensen, P. H., Meltzer, P. S., Janeway, K. A., Gorlick, R., & 1 othersCrompton, B. D., Oct 15 2019, In: Cancer. 125, 20, p. 3514-3525 12 p.. Research output: Contribution to journal › Review article › peer-review ...
Autoexperimentation - Preferred Concept UI. M0010648. Scope note. Intentionally using oneself as a research subject. ...
Autoexperimentation 4. Radioactive fallout and shelter Publication: [Atlanta, GA] : Public Health Service, Audiovisual Facility ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation H1.770.644.302.100 Autogenic Training F4.754.103 F4.754.424.386 Autonomic Fibers, Preganglionic A8.675. ...
Autoexperimentation Autogenic Training Autografts Autoimmune Diseases Autoimmune Diseases of the Nervous System Autoimmune ...
addictions adverse effects anxiété auto experimentation ayahuasca cannabidiol cannabinoïde cannabinoïdes cannabis cannabis ... addictions adverse effects anxiété auto experimentation ayahuasca cannabidiol cannabinoïde cannabinoïdes cannabis cannabis ...
addictions adverse effects anxiété auto experimentation ayahuasca cannabidiol cannabinoïde cannabinoïdes cannabis cannabis ... addictions adverse effects anxiété auto experimentation ayahuasca cannabidiol cannabinoïde cannabinoïdes cannabis cannabis ...

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