Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.PhenylpropionatesSafety: Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.Inpatients: Persons admitted to health facilities which provide board and room, for the purpose of observation, care, diagnosis or treatment.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Food, Genetically Modified: Food derived from genetically modified organisms (ORGANISMS, GENETICALLY MODIFIED).Neurology: A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.Depression: Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.History, 20th Century: Time period from 1901 through 2000 of the common era.History, 19th Century: Time period from 1801 through 1900 of the common era.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Lateral Ventricles: Cavity in each of the CEREBRAL HEMISPHERES derived from the cavity of the embryonic NEURAL TUBE. They are separated from each other by the SEPTUM PELLUCIDUM, and each communicates with the THIRD VENTRICLE by the foramen of Monro, through which also the choroid plexuses (CHOROID PLEXUS) of the lateral ventricles become continuous with that of the third ventricle.Nerve Fibers, Myelinated: A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.Cerebral Ventricles: Four CSF-filled (see CEREBROSPINAL FLUID) cavities within the cerebral hemispheres (LATERAL VENTRICLES), in the midline (THIRD VENTRICLE) and within the PONS and MEDULLA OBLONGATA (FOURTH VENTRICLE).Leukomalacia, Periventricular: Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)Nystagmus, Physiologic: Involuntary rhythmical movements of the eyes in the normal person. These can be naturally occurring as in end-position (end-point, end-stage, or deviational) nystagmus or induced by the optokinetic drum (NYSTAGMUS, OPTOKINETIC), caloric test, or a rotating chair.Nystagmus, Pathologic: Involuntary movements of the eye that are divided into two types, jerk and pendular. Jerk nystagmus has a slow phase in one direction followed by a corrective fast phase in the opposite direction, and is usually caused by central or peripheral vestibular dysfunction. Pendular nystagmus features oscillations that are of equal velocity in both directions and this condition is often associated with visual loss early in life. (Adams et al., Principles of Neurology, 6th ed, p272)Nystagmus, Congenital: Nystagmus present at birth or caused by lesions sustained in utero or at the time of birth. It is usually pendular, and is associated with ALBINISM and conditions characterized by early loss of central vision. Inheritance patterns may be X-linked, autosomal dominant, or recessive. (Adams et al., Principles of Neurology, 6th ed, p275)Electronystagmography: Recording of nystagmus based on changes in the electrical field surrounding the eye produced by the difference in potential between the cornea and the retina.Fixation, Ocular: The positioning and accommodation of eyes that allows the image to be brought into place on the FOVEA CENTRALIS of each eye.Vestibular Diseases: Pathological processes of the VESTIBULAR LABYRINTH which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls.Postural Balance: A POSTURE in which an ideal body mass distribution is achieved. Postural balance provides the body carriage stability and conditions for normal functions in stationary position or in movement, such as sitting, standing, or walking.World War I: Global conflict primarily fought on European continent, that occurred between 1914 and 1918.Famous PersonsPeriodicals as Topic: A publication issued at stated, more or less regular, intervals.VermontNew HampshireJournal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Serial Publications: Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)Self-Help Groups: Organizations which provide an environment encouraging social interactions through group activities or individual relationships especially for the purpose of rehabilitating or supporting patients, individuals with common health problems, or the elderly. They include therapeutic social clubs.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Environmental Illness: A polysymptomatic condition believed by clinical ecologists to result from immune dysregulation induced by common foods, allergens, and chemicals, resulting in various physical and mental disorders. The medical community has remained largely skeptical of the existence of this "disease", given the plethora of symptoms attributed to environmental illness, the lack of reproducible laboratory abnormalities, and the use of unproven therapies to treat the condition. (From Segen, Dictionary of Modern Medicine, 1992)Multiple Chemical Sensitivity: An acquired disorder characterized by recurrent symptoms, referable to multiple organ systems, occurring in response to demonstrable exposure to many chemically unrelated compounds at doses below those established in the general population to cause harmful effects. (Cullen MR. The worker with multiple chemical sensitivities: an overview. Occup Med 1987;2(4):655-61)United StatesReferral and Consultation: The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.Accreditation: Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Joint Commission on Accreditation of Healthcare Organizations: A private, voluntary, not-for-profit organization which establishes standards for the operation of health facilities and services, conducts surveys, and awards accreditation.MarylandConsumer Health Information: Information intended for potential users of medical and healthcare services. There is an emphasis on self-care and preventive approaches as well as information for community-wide dissemination and use.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.

*Frequency following response

Evoked potential Auditory brainstem response Burkard, R., Don, M., & Eggermont, J. J. Auditory evoked potentials: Basic ... is an evoked potential generated by periodic or nearly-periodic auditory stimuli. Part of the auditory brainstem response (ABR ... Moore EJ (1983). Bases of auditory brain-stem evoked responses. Grune & Stratton, Inc. Skoe, E; Kraus, N (June 2010). "Auditory ... "Auditory nonlinearities measured with auditory-evoked potentials". The Journal of the Acoustical Society of America. 87 (3): ...

*Cortical deafness

Brainstem auditory evoked potentials (BAEP), also referred to as brainstem auditory evoked responses (BAER) show the neuronal ... His auditory nerve was tested by evoking responses with normal auditory nerve potentials at 10 dB bilaterally. The results of ... Cortical deafness requires demonstration that brainstem auditory responses are normal, but cortical evoked potentials are ... Auditory middle latency and cortical evoked potentials were grossly abnormal, consistent with the central nature of cortical ...

*Auditory brainstem response

Auditory steady state response is an auditory evoked potential, elicited with modulated tones that can be used to predict ... The auditory brainstem response (ABR) is an auditory evoked potential extracted from ongoing electrical activity in the brain ... Auditory system Bone conduction auditory brainstem response Cochlea EEG Evoked potential Otoacoustic emission Eggermont, Jos J ... Both are auditory evoked potentials. Both use acoustic stimuli delivered through inserts (preferably). Both can be used to ...

*Audiogram

For example when performing the brainstem auditory evoked potentials the patient's brainstem responses are being measured when ... The test varies for children, their response to the sound can be a head turn or using a toy. The child learns what they can do ... Clinical Audiology Lippen-Cott Williams and Wilkins Rubel, E. Popper, A. Fay, R (1998) Development of the Auditory System New ... The most commonly employed measure of auditory status is conventional audiometry (0.5-8 kHz). Conn, P. Michael (2011). Handbook ...

*Clinical neurophysiology

May include visual, auditory, or somatosensory evoked potentials. These record the electrical responses of the brain and spinal ... EMG and evoked potentials, and electrodiagnostic physician focuses mainly on nerve conduction studies, needle EMG, and evoked ... Evoked potentials: Diagnostic test evaluating specific tracts of the central and peripheral nervous system. ... Physiologists perform the majority of EEGs, evoked potentials and a portion of the nerve conduction studies. They are then ...

*Slow vertex response

... is associated with electrophysiological recordings of the auditory system, specifically Auditory evoked potentials (AEPs). The ...

*Audiometry

Audio steady state response (ASSR) audiometry Vestibular evoked myogenic potential (VEMP) test, a variant of ABR that tests the ... audiometry Auditory brainstem response (ABR) is a neurologic tests of auditory brainstem function in response to auditory ( ... wide-band absorbance audiometry also called 3D tympanometry Evoked potential audiometry N1-P2 cortical audio evoked potential ( ... Electrocochleography a variant of ABR, tests the impulse transmission function of the cochlea in response to auditory (click) ...

*Brainstem auditory evoked potential

... also called brainstem auditory evoked responses (BAERs), are very small auditory evoked potentials in response to an auditory ... Long, KJ; Allen, N (October 1984). "Abnormal brain-stem auditory evoked potentials following Ondine's curse". Archives of ... In human neuroanatomy, brainstem auditory evoked potentials (BAEPs), ... Although it is possible to obtain a BAEP to a pure tone stimulus in the hearing range a more effective auditory stimulus ...

*ASSR

... a Swedish trade union of professional workers Auditory steady-state response, a steady-state evoked potential of the brainstem ...

*Music-related memory

An incoming auditory stimulus evokes responses measured in the form of an Event-related potential (ERP), measured brain ... This expert used auditory and motor memory along with conceptual memory. Together the auditory and motor representations allow ... Therefore, there is potential that one's ability to understand and remember will be compromised if one studies with the ... This is indicated by N400, a negative spike at 400ms, as measured by an "event related potential". Musical aptitude Music and ...

*Auditory cortex

An evoked response study of congenitally deaf kittens by Klinke et al. utilized local field potentials to measure cortical ... The auditory cortex has distinct responses to sounds in the gamma band. When subjects are exposed to three or four cycles of a ... The evoked responses during the sixth and seventh omitted notes are assumed to be imagined, and were characteristically ... The right auditory cortex has long been shown to be more sensitive to tonality, while the left auditory cortex has been shown ...

*Intraoperative neurophysiological monitoring

... transcranial electrical motor evoked potentials (TCeMEP), EEG, EMG, and auditory brainstem response (ABR). For a given surgery ... Motor evoked potentials have also been used in surgery for Thoracic aortic aneurysm. Intraoperative monitoring is used to : to ... Since the 1970s, SSEP (somatosensory evoked potentials) have been used to monitor spinal cord function by stimulating a nerve ... More recently, transcranial electric motor evoked potentials (TCeMEP) have also been used for spinal cord monitoring. This is ...

*Evoked potential

Auditory evoked potentials (AEPs) are a subclass of event-related potentials (ERP)s. ERPs are brain responses that are time- ... evoked potential Stereo-elicited visual evoked potential Steady state visually evoked potential Auditory evoked potential can ... visual evoked potential Chromatic visual evoked potential Hemi-field visual evoked potential Flash visual evoked potential LED ... visual evoked potential Motion visual evoked potential Multifocal visual evoked potential Multi-channel visual evoked potential ...

*N100

The Mismatch negativity (MMN) is an evoked potential that occurs at roughly the same time as N100 in response to rare auditory ... The N100 is a slow-developing evoked potential. From one to four years of age, a positive evoked potential, P100, is the ... Older children start to develop a negative evoked potential at 200 ms that dominates evoked potentials until adolescence; this ... "the amplitude of the self-evoked response actually exceeded that of the machine-evoked potential". Being warned about an ...

*Stimulus modality

The ABR, also known as the brainstem auditory evoked response (BAER) test or auditory brainstem evoked potential (ABEP) test ... Otoacoustic emissions test (OAE) and auditory brainstem response (ABR) testing measures the brain's response to sounds. The OAE ... Tactual perception is achieved through the response of mechanoreceptors in the skin that detect physical stimuli. The response ... test and auditory brainstem response (ABR) test. During a whispered speech test, the participant is asked to cover the opening ...

*Vestibular evoked myogenic potential

... system Electrophysiology Evoked potential Auditory evoked potential Visual evoked potential Auditory brainstem response ... angular vestibular evoked potentials (VsEPA) and linear vestibular evoked potentials (VsEPL). VsEPA stimuli needs to be a brief ... the response was small (although large compared to many evoked potentials) and required averaging, and only the initial ... The vestibular evoked myogenic potential (VEMP or VsEP) is a neurophysiological assessment technique used to determine the ...

*Ear-EEG

Auditory evoked responses from Ear-EEG recordings. EMBC 2012. San Diego, Cal. Bleichner, Martin (6 April 2015). "Exploring ... Other potential use cases which are known to have been explored are driver drowsiness detection, BCI and biometric ... "Auditory evoked responses from Ear-EEG recordings". Since then, it has grown to be an endeavor spread across multiple research ... Ear-EEG Allows Extraction of Neural Responses in Challenging Listening Scenarios - A Future Technology for Hearing Aids?. EMBC ...

*Electrocochleography

The auditory nerve action potential is the most widely studied component in ECochG. The AP represents the summed response of ... Moore EJ (1983). Bases of auditory brain-stem evoked responses. Grune & Stratton, Inc. Fromm B, et al. (1934-1935). "Studies in ... Auditory evoked potential Cochlea EEG Electrophysiology Ferraro, John A. (November 15, 2000). "Clinical Electrocochleography: ... When a certain threshold potential is reached, the spiral ganglion neuron fires an action potential, which enters the auditory ...

*Brainwave entrainment

Burkard, R., Don, M., and Eggermont, J. J., Auditory evoked potentials: Basic principles and clinical application. Philadelphia ... The Frequency following response (FFR), also referred to as Frequency Following Potential (FFP), is a specific response to ... Worden FG, Marsh JT (1968). "Frequency-following (microphonic-like) neural responses evoked by sound". Electroencephalography ... in response to an auditory stimuli, such as a piece of music with a consistent rhythm. Furthermore, motor synchronization to ...

*Spinocerebellar ataxia type 1

Individuals with SCA1 often exhibit abnormal brainstem auditory evoked potential, including prolonged latency and absent or ... using electrodes on the scalp to detect changes in electric potential within the brain in response to sensations or movements. ... The same study also found abnormalities in visual evoked potential and median somatosensory evoked potential in some SCA1 ... Chandran V, Jhunjhunwala K, Purushottam M, Jain S, Pal PK (July 2014). "Multimodal evoked potentials in spinocerebellar ataxia ...

*P200

Like other evoked-response potentials, the presence of the P2 is revealed in the waveform of the EEG recorded by time-locking ... 2003, Enhancement of Neuroplastic P2 and N1c Auditory Evoked Potentials in Musicians, Journal of Neuroscience, 2 July 2003, 23( ... Researchers recorded visual evoked potentials in response to non-stereoscopic two-dimensional and three-dimensional images in ... The component is evoked as part of the normal response to visual stimuli, but the amplitude and latency (delay between stimulus ...

*Steady state topography

The sinusoidal flicker elicits an oscillatory brain electrical response known as the Steady State Visually Evoked Potential ( ... Steady State Visually Evoked Potential Correlates of Auditory Hallucinations in Schizophrenia. Neuroimage. 1998;.8:370-376. ... Regan, D., (1989). Human Brain Electrophysiology: Evoked Potentials and Evoked Magnetic Fields in Science and Medicine. ... Srinivasan, R., Bibi, F.A., Nunez, P.L., (2006) Steady-state visual evoked potentials: distributed local sources and wave-like ...

*Cochlear nucleus

Electrical stimuli to the auditory nerve evoke a graded excitatory postsynaptic potential in the octopus cells. These EPSPs are ... Octopus cells produce an "Onset Response" to simple tonal stimuli. That is, they respond only at the onset of a broad-band ... Auditory nerve fibers, fibers that travel through the auditory nerve (also known as the cochlear nerve or eighth cranial nerve ... Briefly, there are around 30,000 auditory nerve fibres in each of the two auditory nerves. Each fiber is an axon of a spiral ...

*Lüder Deecke

... and as a third project the alterations of the auditory evoked potentials under respiratory stress. In 1978 a further Citation ... Latency changes of the human auditory evoked response during hyperventilation, hypoxia, asphyxia, and hypercapnia. Aerospace ... directed attention potential, and relaxation potential. Anticipatory activity of the limbic and frontal cortex. In: Karrer R, ... readiness potential and reafferent potentials". Pflugers Archiv: European Journal of Physiology. 468 (7): 1115-24. doi:10.1007/ ...

*Oddball paradigm

2007). EVENT-RELATED POTENTIALS DURING AUDITORY ODDBALL, AND COMBINED AUDITORY ODDBALL-VISUAL PARADIGMS. International Journal ... The classic auditory oddball paradigm can be modified to produce different neural responses and can therefore be used to ... 1975) Two varieties of long-latency positive waves evoked by unpredictable auditory stimuli in man. Electroencephalogr Clin ... G.A. Book, M.C. Stevens, G. Pearlson, K.A. Kiehl - Fusion of fMRI and the Pupil Response During an Auditory Oddball Task - ...
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Phone: 778-317-4952. Many factors, both genetic and environmental, have been blamed for increasing the risk of a diagnosis of schizophrenia. Some, such as a family history of schizophrenia, are widely accepted. Others, such as infection with Toxoplasma gondii, a parasite transmitted by soil, undercooked meat and cat feces, are still viewed with skepticism.. A new study by Gary Smith, professor of population biology and epidemiology at the University of Pennsylvanias School of Veterinary Medicine, used epidemiological modeling methods to determine the proportion of schizophrenia cases that may be attributable to T. gondii infection. The work, published in the journal Preventive Veterinary Medicine, suggests that about one-fifth of cases may involve the parasite.. "Infection with Toxoplasma is very common, so, even if only a small percentage of people suffer adverse consequences, we could be talking about problems that affect thousands and thousands of people," Smith said.. In the United States, ...
TY - JOUR. T1 - Decreased BDNF in patients with antipsychotic naïve first episode schizophrenia. AU - Jindal, Ripu D.. AU - Pillai, Anilkumar R. AU - Mahadik, Sahebrao P.. AU - Eklund, Kevin. AU - Montrose, Debra M.. AU - Keshavan, Matcheri S.. PY - 2010/6/1. Y1 - 2010/6/1. N2 - Objective: Brain-derived neurotrophic factor (BDNF) is a key factor known to mediate neuronal proliferation, differentiation, survival and response to stress. Decreases in BDNF levels have been reported in schizophrenia, but studies in treatment naïve patients are few. Herein we report on serum BDNF levels in a series of patients with first-episode treatment naïve psychoses in comparison to age matched healthy controls. Method: Fasting serum BDNF levels were measured in 41 patients with treatment naive first episode psychosis (24 with schizophrenia, schizoaffective disorder or schizophreniform disorder, and 17 with non-schizophrenia psychotic disorders) and 41 age-matched healthy controls. Results: A three group ...
The neurodevelopmental hypothesis. This theory attempts to link together a number of different research findings on the development of Schizophrenia. It is more common for people with Schizophrenia to have had a viral illness early in their foetal development. It has also been found that babies who experience difficulties at birth resulting in lack of oxygen to the brain have an increased risk of developing Schizophrenia. In addition, brain scans of people with Schizophrenia show that compared to the rest of the population, there are differences in their brains. These studies have established that people with Schizophrenia have higher levels of structural brain abnormalities. Together these findings suggest a link between damage to the developing brain and development of Schizophrenia in later life.. The use of drugs. The role of specific street-drugs in the development of Schizophrenia has become a topic of increasing interest in recent years. Research suggests that use of cannabis increases ...
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The Schizophrenia Research Forum, (SRF) is recognized in the community of researchers in psychiatric disease as a reliable and respected resource for rapid news, discussion and information. Their Mission is to help researchers in their quest for causes, improved treatments, and better understanding of schizophrenia. The Schizophrenia Research Forum has recently launched a monthly podcast. Click here to listen and subscribe.. Visit the Schizophrenia Research Forum website: www.schizophreniaforum.org. ...
Teenage schizophrenia is connected with formation of a pathological mental state in perception of environment. At first there are nervous breakdowns, tearfulness, temper tantrum and loss of strength. The first signs of teenager schizophrenia can be distinguished in the early childhood.. The main signs of malignant teenager schizophrenia are: fast forcing of negative emotions, intellect disorder with the expressed autism, mobility decrease, loss of strength and emotions. Childrens schizophrenia proceeds more severe than teenage, with emphasis on oligophrenia.. Schizophrenia is very widespread. From 5 mentally sick teenagers 1-2 are schizophrenics. Nevertheless between adult and teenage schizophrenia there are serious differences. There are some types of teenager schizophrenia.. Process schizophrenia. This kind is detected in early childhood. At teenage the illness progresses. The first clinical signs are noticeable by 3 years. The child becomes flaccid, badly perceives reality, aloofness from ...
In the past ten years, major developments in scientific research have drastically changed the way schizophrenia is viewed. Neuroscience, in particular, has enabled researchers to frame different questions when investigating this illness and we are now coming to a deeper understanding of it.In this much-needed book, Michael Green, an expert in the neurocognition of schizophrenia, presents an integrated overview of schizophrenia covering a wide range of topics in lively, understandable prose. He outlines a neurodevelopmental model of schizophrenia, discusses neurocognitive indicators of genetic vulnerability, the introduction of a new generation of medications, recent findings from brain imaging, cognitive remediation, and the determinants of functional outcome. He presents a modern view of schizophrenia based on neuroscience that goes far beyond the symptoms of the illness.Schizophrenia Revealed gives the reader an important overview of the most recent developments in our understanding of schizophrenia.
21 Jan 2009 All Content, Article Title, Abstract, Keywords, Authors, Article Title, Abstract Many people with schizophrenia experience stigma caused by other peoples survey in 27 countries, in centres affiliated to the INDIGO Research Network, Anticipated discrimination affected 469 (64%) in applying for work, BibSonomy :: Publikation :: IT Development and Management of a Live e-Research System - Experiences with the Australian Schizophrenia Research Bank. Schizophrenia Research Papers Brain mapping confirms patients with schizophrenia have impaired ability to imitate. by David Salisbury , Mar. 14, 2014, 12:00 AM , Want The latest round of projects to be funded by the Institute was announced yesterday, which will partly inform the direction of the Institutes research in the coming title for romeo and juliet essay yahoo title for rosa parks essay title for schizophrenia research paper title for segregation essay title for smoking 24 Feb 2016 Isee essay topics Geography dissertation examples ...
Metabolic profile at first-time schizophrenia diagnosis: a population-based cross-sectional study Henriette Thisted Horsdal,1,2 Michael Eriksen Benros,2,3 Ole Köhler-Forsberg,2–4 Jesper Krogh,3 Christiane Gasse1,2,5 1National Centre for Register-based Research, Department of Economics and Business Economics, Aarhus BSS, Aarhus University, Aarhus, 2The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 3Faculty of Health Sciences, Mental Health Centre Copenhagen, University of Copenhagen, Copenhagen, 4Psychosis Research Unit, Aarhus University Hospital, Risskov, 5Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark Objective: Schizophrenia and/or antipsychotic drug use are associated with metabolic abnormalities; however, knowledge regarding metabolic status and physician’s monitoring of metabolic status at first schizophrenia diagnosis is sparse. We assessed the prevalence of monitoring for metabolic blood abnormalities
Effects Of CBD On Schizophrenia,This is precisely for both the endocannabinoids - anandamide and 2-AG - and also for plant cannabinoids such as THC.
1. What is schizophrenia?. Schizophrenia is a chronic, incurable (but treatable) mental disorder affecting 1% of Americans, causing them to hallucinate, or have paranoid or disturbed thoughts. These symptoms can be pretty terrifying, and often cause sufferers to act irrationally and strangely. A combination of therapy and medication can alleviate the symptoms, and help those with schizophrenia to live normal lives. 2. How does schizophrenia affect the mind?. Symptoms of schizophrenia can include hallucinations, paranoid thoughts and behavior, and depression. People suffering from the disorder often make statements that are nonsensical, reflecting their disturbed thought process. Sufferers may experience difficulty organizing or filtering their thoughts and statements. Contrary to popular belief, schizophrenia is a different disorder than dissociative identity disorder (multiple personalities).. 3. How does schizophrenia affect behavior?. Schizophrenia and the scary chaos it causes in a persons ...
Schizophrenia is a severe mental illness with a lifetime morbidity risk close to 1 %, involving both genetic and environmental risk factors. Prospective studies have shown that heavy use of cannabis in adolescence moderately increases the risk of developing schizophrenia. Many data have also suggested that the co-occurrence of cannabis abuse in patients with schizophrenia has a deleterious impact on the clinical outcome of schizophrenia. Cannabis abuse by schizophrenic patients is a significant public health problem for which there is no empirically validated treatment. We are presently studying the efficiency of motivational therapy on cannabis consumption in patients with schizophrenia.. 330 patients with schizophrenia and cannabis abuse or dependence (according to DSM-IV criteria) are randomly assigned to 4 motivational interview during one month or usual intensive treatment. Treatment is conducted in outpatient which are evaluated at the inclusion and at 6 month with Time-Line Follow Bach ...
The past decade has seen renewed interest in the neuropathology of schizophrenia. The advent of new postmortem techniques and functional imaging, along with a greater understanding of the neuropsychology of schizophrenia, have provided many new clues to the nature of the underlying brain dysfunction in this disorder. There has also been a greater understanding of the presence of severe cognitive dysfunction among many elderly persons with schizophrenia. In this article, a series of investigations are described that seek to answer basic questions about the neuropathology of schizophrenia, in particular as it pertains to cognitive impairment. The first study describes neuropathological findings in 100 consecutively autopsied persons with schizophrenia, the majority of whom had had detailed antemortem assessments. Results from this first study prompted the conclusion that schizophrenia is not characterized by classical, histologically identifiable neuropathology. Moreover, most cases of dementia in ...
There have been a number of recent anouncements (see earlier stories in our Daily Schizophrenia News blog - in May, if I remember correctly) that research teams in the UK and at Yale University - have developed the ability (with a high degree of accuracy - of 95% or higher) to identify the key brain changes that result in schizophrenia, well before (up to years before) the person shows outward signs or symptoms of schizophrenia (which it is now confirmed only become noticeable to most people well after the disease and the brain damage has progressed. This early diagnosis offers the opportunity to intervene in the disease process well-before it gets to the point of being full-blown schizophrenia - with the potential to prevent the development of the disease.. Today another news story comes out - that seems to be a duplicate of these earlier stories - and states that:. "Using imaging software, doctors at the Royal Edinburgh Hospital and Edinburgh University have identified changes in the brain ...
The public radio program "Speaking of Faith" is currently broadcasting a program called "Room for J: One Familys Struggle with Schizophrenia." Js diagnosis of schizophrenia causes him to believe that he is God. The program host speaks with Js parents and brother, shares excerpts from Js writing, and speaks with other experts about schizophrenia as a biologically-based brain disease.. Delusions are a common positive symptom of schizophrenia, and they can often become intensely religious in nature.. Tune into the program live from July 15-20, 2005 on your local radio station , or listen to a streaming audio file online from the program archives.. Information about this program was sent to us by a schizophrenia.com member, who learned of it from NAMI. Thank you for sharing this information!. ...
TY - JOUR. T1 - The impact of genome-wide supported schizophrenia risk variants in the neurogranin gene on brain structure and function. AU - Walton, Esther. AU - Geisler, Daniel. AU - Hass, Johanna. AU - Liu, Jingyu. AU - Turner, Jessica. AU - Yendiki, Anastasia. AU - Smolka, Michael N. AU - Ho, Beng-Choon. AU - Manoach, Dara S. AU - Gollub, Randy L. AU - Roessner, Veit. AU - Calhoun, Vince D. AU - Ehrlich, Stefan. PY - 2013. Y1 - 2013. N2 - The neural mechanisms underlying genetic risk for schizophrenia, a highly heritable psychiatric condition, are still under investigation. New schizophrenia risk genes discovered through genome-wide association studies (GWAS), such as neurogranin (NRGN), can be used to identify these mechanisms. In this study we examined the association of two common NRGN risk single nucleotide polymorphisms (SNPs) with functional and structural brain-based intermediate phenotypes for schizophrenia. We obtained structural, functional MRI and genotype data of 92 schizophrenia ...
Background: The majority (about 75%) of patients with childhood onset schizophrenia still have impairing cognitive and psychotic symptoms after drug treatment optimization. Recent studies with transcranial magnetic stimulation (TMS) indicate moderate efficacy in symptom reduction in adult patients with schizophrenia. Transcranial direct current stimulation (TDCS) may be a safe and effective additional treatment of residual symptoms of schizophrenia in medication stable patients. Recent research into adult-onset schizophrenia established both safety and efficacy in 20-minute daily DC polarization (TDSC).. Objective: To establish whether bilateral DC polarization (using TDCS) of either dorsolateral prefrontal cortex or superior temporal cortex is safe in patients with childhood onset schizophrenia and whether it is associated with improvement in cognitive performance or reduction in auditory hallucination (psychotic symptoms) respectively.. Study population: Up to 40 patients ...
TY - JOUR. T1 - An association between autumn birth and clozapine treatment in patients with schizophrenia: A population-based analysis. AU - Sørensen, Holger Jelling. AU - Foldager, Leslie. AU - Røge, Rasmus. AU - Pristed, Sofie Gry. AU - Andreasen, Jesper T.. AU - Nielsen, Jimmi. PY - 2014. Y1 - 2014. N2 - Background: Numerous studies on seasonality of birth and schizophrenia risk have been published but it is uncertain whether, among those with schizophrenia, refractory illness exhibits any predilection for birth month. We hypothesized and examined whether a season of birth effect was present in patients with schizophrenia with a history of clozapine treatment. Method: Using record linkage with Danish registers, we examined patients with schizophrenia born between 1950 and 1970, and between 1995 and 2009 and Cox regression analysis was used to examine season of birth in relation to history of clozapine treatment. Results: In a study population corresponding to 60,062 person-years from 5328 ...
Pimozide is a high potency antipsychotic medication which has been used in many countries since the 1970s for the treatment of schizophrenia and other psychoses. In the US, it was licensed in the past decade as an "orphan drug" for the treatment of Tourettes syndrome.. Sultana and McMonagle have identified randomised controlled trials of pimozide for the treatment of schizophrenia. Not surprisingly, pimozide was found to be more effective than placebo for preventing relapse and was similar to other typical antipsychotic drugs in efficacy and side effect profile.. Several unanswered questions remain. It has been claimed that pimozide is more effective than other typical antipsychotic drugs for treating negative symptoms of schizophrenia.1 None of the studies included in the review specifically reported on negative symptoms as an outcome, so the review was unable to support or refute this claim. In addition, the efficacy of pimozide relative to the newer atypical antipsychotic drugs is unknown ...
INTRODUCTION: There is converging evidence supporting hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis in schizophrenia spectrum disorders (SSD), such as schizotypal personality disorder (SPD), first-episode schizophrenia (FESZ) and chronic schizophrenia (CHSZ). Such an aberrant HPA activity might have volumetric consequences on the pituitary gland. However, previous magnetic resonance imaging (MRI) studies assessing pituitary volume (PV) in SSD are conflicting. The main objective of this study was to examine further PV in SSD. METHODS: PV were manually traced on structural MRIs in 137 subjects, including subjects with SPD (n = 40), FESZ (n = 15), CHSZ (n = 15), and HC (n = 67). We used an ANCOVA to test PV between groups and gender while controlling for inter-subject variability in age, years of education, socioeconomic status, and whole brain volume. RESULTS: Overall, women had larger PV than men, and within the male sample all SSD subjects had smaller PV than HC, statistically ...
LETTERS TO EDITOR. Functional psychosis in childhood and adolescence Dear Editors,. We read with great interest the Supplement 2 of the Jornal de Pediatria about Mental Health, especially the paper entitled "Functional Psychosis in Childhood and Adolescence" by Tengan & Maia.1 They discussed in this text an important issue in child psychiatry, the distinction between childhood-onset schizophrenia and autism.. Since the works of Kolvin & Rutter,2 autism was reliably separated from early-onset schizophrenia, becoming one of the best-validated distinctions in child psychiatry, but a striking feature of childhood-onset schizophrenia samples relative to adult-onset schizophrenia is the higher rate of early language, social, and motor developmental abnormalities. Pre-morbid social impairment was the most common feature, present in 50-87% of childhood-onset schizophrenia cases across five independent research centers.3. The full syndromes of schizophrenia and autism seem to be distinct, however it is ...
TY - JOUR. T1 - Critical review of antipsychotic polypharmacy in the treatment of schizophrenia. AU - Fleischhacker, W. Wolfgang. AU - Uchida, Hiroyuki. PY - 2014. Y1 - 2014. N2 - Antipsychotic polypharmacy remains prevalent; it has probably increased for the treatment of schizophrenia in real-world clinical settings. The current evidence suggests some clinical benefits of antipsychotic polypharmacy, such as better symptom control with clozapine plus another antipsychotic, and a reversal of metabolic side-effects with a concomitant use of aripiprazole. On the other hand, the interpretation of findings in the literature should be made conservatively in light of the paucity of good studies and potentially serious side-effects. Also, although the available data are still limited, two smaller-scale clinical trials provide preliminary evidence that converting antipsychotic polypharmacy to monotherapy could be a valid and reasonable treatment option. Several studies have explored strategies to change ...
The Scariest Word in the English Language - a public lecture on schizophrenia. Presented by the H.C. Coombs Creative Arts Fellow, Dr Gabrielle Carey, in collaboration with Dr. Julia Brown What did Nobel Prize winner Josh Nash, Fleetwood Macs Peter Green and James Joyces daughter all have in common? Schizophrenia.
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Background Childhood-onset schizophrenia is a severe form of psychotic disorder that occurs at age 12 years or younger and is often chronic and persistently debilitating. The definition of childhood schizophrenia has evolved over time and is now believed to be a virulent childhood version of the same disorder exhibited in adolescents and adults. The American Psychiatric Associations Diagnostic Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) cautions that although the essential features of schizophrenia are the same in childhood, it is harder to diagnose. Children may experience less elaborate delusions and hallucinations than adults. Visual hallucinations are more common in child schizophrenics and should be distinguished from normal fantasy play. Symptoms such as disorganized speech and behavior, which are typically present in schizophrenia, also occur in many disorders of childhood onset (e.g., autism spectrum disorder and attention-deficit hyperactivity disorder). It is ...
Types of schizophrenia include paranoid schizophrenia, disorganized schizophrenia, Catatonic Schizophrenia, Residual Schizophrenia etc
The latest report by IMARC Group titled, "Rice Bran Oil Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2017-2022", finds that the global rice bran oil market has grown at a CAGR of 3% during 2009-2016, reaching a production volume of around 1.5 Million Tons in 2016. Rice bran oil is extracted from the germ and the husk of rice kernels, and contains a unique anti-oxidant known as gamma-oryzanol. It is also a great source of natural bioactive phytoceuticals such as γ-oryzanol, tocotrienols (tocols), tocopherols, etc. Although rice bran oil is similar in composition to peanut butter, it has some advantages over it and is the most preferred oil type in many regions, especially in the Asian cultures. The market for rice bran oil is gaining momentum in other parts of the globe owing to its relatively low price and various health benefits.. Request a free sample copy of the report: http://www.imarcgroup.com/request?type=report&id=651&flag=B. The major factors which have ...
In schizophrenia, subtle aberrations in the brain cause functional disturbances like psychotic symptoms and social disability. There are, however, also disturbances outside the CNS indicating a systemic manifestation in the disease. The aim of the present thesis was to gain deeper understanding of the pathophysiological mechanisms underlying schizophrenia with a particular interest in peripheral and systemic manifestations with relevance for the increased risk of obesity and metabolic complications seen in the disease. Therefore, resting energy expenditure (REE), physical capacity, and relevant body composition variables were measured in patients with schizophrenia and in healthy controls. Also niacin skin flush response and electrodermal activity (EDA) were studied.. Patients with schizophrenia exhibited significantly lower REE expressed as kJ/kg, and also lower values compared with predicted levels than the controls. The difference could not be attributed to medication or variations in body ...
The present study was an attempt to examine the relationship between personality variables and neuropsychological deficits in chronic schizophrenic subjects. The groups were composed of 73 chronic schizophrenic subjects with measureable cortical atrophy on CAT-Scan and 118 chronic schizophrenic subjects without identifiable brain damage. The relationship between neuropsychological deficit and personality variables was tested by means of discriminant analysis. As hypothesized, the brain-damaged group was found to have a stronger relationship between the neuropsychological deficits and the personality variables than the nonbrain-damaged group. Canonical correlation was used to demonstrate the underlying neuropsychological pattern which was found related to the personality profile of the MMPI for the entire sample of chronic schizophrenics. A frontal and anterior temporal lobe neuropsychological profile was found related to a particular personality profile.
Dissociation in schizophrenia and borderline personality disorder Ondrej Pec,1,2 Petr Bob,1,3 Jiri Raboch1 1Center for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry, First Faculty of Medicine, Charles University, Prague, 2Psychotherapeutic and Psychosomatic Clinic ESET, Prague, 3Central European Institute of Technology, Faculty of Medicine, Masaryk University, Brno, Czech Republic Background: Dissociation likely plays a key role in schizophrenia and borderline personality disorder (BPD), although empirical studies that compare specific manifestations of these symptoms in schizophrenia and BPD are rare. In this context, the purpose of this study was to compare the occurrence of dissociative and other psychopathological symptoms in these disorders, and to assess the possible influence of antipsychotic medication on the dissociative symptoms. Methods: We assessed 31 patients with schizophrenia and 36 patients with BPD. Dissociative symptoms were measured by the Dissociative
Michelle Hammer wants to draw attention to the 3.5 million Americans living with schizophrenia.. Although schizophrenia affects roughly 1.1 percent of the worlds population, its rarely talked about openly. Fortunately, graphic designer Michelle Hammer is hoping to change that.. Hammer, whos the founder of Schizophrenic NYC, wants to draw attention to the 3.5 million Americans living with this disorder. She plans on doing that through visually unique and beautiful merchandise inspired by several facets of schizophrenia.. For instance, one of her designs is based on a Rorschach test. This common inkblot test is often given to people during psychological testing. People who are schizophrenic tend to view this test from a very different perspective than the average person. (Its important to note that though the test has long been used to diagnose schizophrenia, some experts today question the accuracy of the test.) Using vibrant colors and unique patterns, Michelles designs mimic these ...
Objectives Endophenotypes in schizophrenia research is a contemporary approach to studying this heterogeneous mental illness, and several candidate neurophysiological markers (e.g. P50 sensory gating) and neuropsychological tests (e.g. Continuous Performance Test (CPT) and Wisconsin Card Sorting Test (WCST)) have been proposed. However, the clinical utility of a single marker appears to be limited. In the present study, we aimed to construct a diagnostic model incorporating P50 sensory gating with other neuropsychological tests in order to improve the clinical utility. Methods We recruited clinically stable outpatients meeting DSM-IV criteria of schizophrenia and age- and gender-matched healthy controls. Participants underwent P50 sensory gating experimental sessions and batteries of neuropsychological tests, including CPT, WCST and Wechsler Adult Intelligence Scale Third Edition (WAIS-III). Results A total of 106 schizophrenia patients and 74 healthy controls were enrolled. Compared with healthy
OBJECTIVE: The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study examined the comparative effectiveness of antipsychotic treatments for individuals with chronic schizophrenia. Patients who had discontinued antipsychotic treatment in phases 1 and 2 were eligible for phase 3, in which they selected one of nine antipsychotic regimens with the help of their
TY - JOUR. T1 - Mirror neuron function, psychosis, and empathy in schizophrenia. AU - McCormick, Laurie M.. AU - Brumm, Michael C.. AU - Beadle, Janelle N.. AU - Paradiso, Sergio. AU - Yamada, Thoru. AU - Andreasen, Nancy. PY - 2012/3/31. Y1 - 2012/3/31. N2 - Processing of social and emotional information has been shown to be disturbed in schizophrenia. The biological underpinnings of these abnormalities may be explained by an abnormally functioning mirror neuron system. Yet the relationship between mirror neuron system activity in schizophrenia, as measured using an electroencephalography (EEG) paradigm, and socio-emotional functioning has not been assessed. The present research measured empathy and mirror neuron activity using an established EEG paradigm assessing the integrity of the Mu rhythm (8-13. Hz) suppression over the sensorimotor cortex during observed and actual hand movement in 16 schizophrenia-spectrum disorder (SSD) participants (n= 8 actively psychotic and n= 8 in residual ...
TY - JOUR. T1 - Second-generation antipsychotic medications in the treatment of mood disorders. T2 - Focus on aripiprazole. AU - Buckley, Peter F.. PY - 2005/1/1. Y1 - 2005/1/1. N2 - Second-generation antipsychotic medications offer a broader range of therapeutic efficacies than first-generation agents. Consequently, our field has witnessed a rapid expansion of the use of second-generation antipsychotic drugs for several conditions beyond psychosis. The use of second-generation antipsychotic medications has been most pronounced in mood disorders, especially in bipolar disorders. Information about the agents clozapine, risperidone, olanzapine, quetiapine, ziprasidone and aripiprazole in terms of their efficacy and tolerability in bipolar disorder is now available. Aripiprazole, a new agent whose proposed mechanism(s) of action differs from that of other agents, has been shown in placebo-controlled comparative trials in bipolar patients to be an effective and well tolerated treatment option for ...
Common single-nucleotide polymorphisms (SNPs) account for a large proportion of the heritability of obsessive-compulsive disorder (OCD). Co-ocurrence of OCD and schizophrenia is commoner than expected based on their respective prevalences, complicating the clinical management of patients. This study addresses two main objectives: to identify particular genes associated with OCD by SNP-based and gene-based tests; and to test the existence of a polygenic risk shared with schizophrenia. The primary analysis was an exon-focused genome-wide association study of 370 OCD cases and 443 controls from Spain. A polygenic risk model based on the Psychiatric Genetics Consortium schizophrenia data set (PGC-SCZ2) was tested in our OCD data. A polygenic risk model based on our OCD data was tested on previous data of schizophrenia from our group. The most significant association at the gene-based test was found at DNM3 (P=7.9 × 10(-5)), a gene involved in synaptic vesicle endocytosis. The polygenic risk model ...
The dopamine hypothesis continues to provide the principal conceptual gateway into the mysteries of schizophrenia. Therefore the measurement and dynamic assessment of HVA, the major metabolite of dopamine, offer opportunities for obtaining substantial understanding of dopamines role in many diseases, of which schizophrenia is but one. Here in one convenient book, clinician and researcher alike can finally find the facts about plasma HVA and its central importance in the biology of schizophrenia. In this book, a compendium of contributions from many of the worlds experts in biological psychiatry, the reader will find the most definitive, authoritative, and clearly written descriptions of the latest research on the usefulness of plasma HVA. These include treatment response to neuroleptics, the relation of this dopamine metabolite to the waxing and waning of positive symptoms and to schizophrenia-related conditions like schizotypal personality disorder, and carefully crafted critiques of current ...
This multisite study was conducted to compare the efficacy and tolerability of combination treatment with clozapine plus aripiprazole versus combination treatment with clozapine plus haloperidol in patients with schizophrenia who do not have an optimal response to clozapine. Patients continued to take clozapine and were randomly assigned to receive daily augmentation with aripiprazole or haloperidol. Physicians prescribed the allocated treatments according to usual clinical care. Withdrawal from allocated treatment within 3 months was the primary outcome. Secondary outcomes included severity of symptoms on the Brief Psychiatric Rating Scale and antipsychotic subjective tolerability on the Liverpool University Neuroleptic Side Effect Rating Scale. A total of 106 patients with schizophrenia were randomly assigned to treatment. After 3 months, we found no difference in the proportion of patients who discontinued treatment between the aripiprazole and haloperidol groups (13.2% vs 15.1%, P = 0.780). The 3
In psychotic disorders, early intervention with antipsychotic medications increases the likelihood of favourable long-term course. However, the pharmacologic management especially with conventional antipsychotic medications is complicated by a high rate of adverse effects including sexual dysfunction. This study aims to determine the demographic and clinical factors associated with sexual dysfunction among male psychiatric outpatients on conventional antipsychotic medications in South-western Nigeria. Two hundred and seventy five consecutive male outpatients with psychotic disorders on conventional antipsychotic medications were interviewed. Data was collected on demographic characteristics, illness-related and medication-related variables. Illness severity was assessed with the Brief psychiatric rating scale. The International Index of Erectile Function questionnaire was used to assess for sexual dysfunctions. A total of 111 (40.4%) respondents had one or more forms of sexual dysfunction. Sexual desire
BACKGROUND: Recent literature documents a stronger association between nonfasting triglycerides (TG) and cardiovascular risk compared to fasting TG. Given concerns over antipsychotic effects on serum TG, this analysis explored changes in nonfasting TG in phase 1 of the CATIE Schizophrenia Trial.METHODS: Change in nonfasting TG, adjusted for baseline value, was compared between
Dr. Carrie Bearden received her Ph.D. in Clinical Psychology from the University of Pennsylvania and joined the UCLA faculty as Assistant Professor in the Department of Psychiatry & Biobehavioral Sciences at UCLA in 2003. She hold a secondary appointment in the Department of Psychology. She has received numerous awards and honors, including Young Investigator Awards from the International Congress for Schizophrenia Research and the National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD), and the American College of Neuropsychopharmacology (ACNP), the A.E. Bennett Neuropsychiatric Research Award for Clinical Science in Biological Psychiatry, and the Samuel Gershon Junior Investigator Award from the International Society for Bipolar Disorders. Dr. Beardens research aims to understand genetic influences on brain structure in the development of psychosis, using converging methods to study cognition and neuroanatomy in clinical high-risk samples (e.g., adolescents at ...
Machine generated contents note: 1. Classification in Psychiatry -- 2. Psychiatric Interview, History, and Mental Status Examination -- 3. Medical Assessment and Laboratory Testing in Psychiatry -- 4. Schizophrenia Spectrum and Other Psychotic Disorders -- 4.1. Schizophrenia -- 4.2. Schizoaffective Disorder -- 4.3. Schizophreniform Disorder -- 4.4. Delusional Disorder and Shared Psychotic Disorder -- 4.5. Brief Psychotic Disorder, Other Disorders, and Catatonia -- 5. Mood Disorders -- 5.1. Major Depression and Bipolar Disorder -- 5.2. Dysthymia and Cyclothymia -- 6. Anxiety Disorders -- 6.1. Overview -- 6.2. Panic Disorder -- 6.3. Agoraphobia -- 6.4. Specific Phobia -- 6.5. Social Anxiety Disorder (Social Phobia) -- 6.6. Generalized Anxiety Disorder -- 6.7. Other Anxiety Disorders -- 7. Obsessive-Compulsive and Related Disorders -- 7.1. Obsessive-Compulsive Disorder -- 7.2. Body Dysmorphic Disorder -- 7.3. Hoarding Disorder -- 7.4. Hair-Pulling Disorder (Trichotillomania) -- 7.5. Excoriation ...
The aim of this study was to test whether personality traits of impulsivity, sensitivity to punishment and reward, and sensation seeking were associated with adults with ADHD and to test whether these measured traits were aspects of the clinical phenotype or instead predisposing personality risk factors for ADHD. Our results suggest that high impulsivity traits, hypersensitivity to reward and susceptibility to boredom are part of the clinical phenotype of adults with ADHD, rather than personality traits harbouring an increased risk for the disorder, as unaffected first-degree relatives did not show a similar pattern of traits. Moreover, results also show that in this study adults with ADHD are not more indifferent to punishment or more sensation seekers than their relatives and controls. These results could not be explained by nonspecific confounds such as age since it was not statistically different between groups. A limitation of the study may be the difference in IQ between ADHD and control ...
Brief psychotic disorder is a period of psychosis whose duration is generally shorter, is not always non-recurring, but can be, and is not caused by another condition. The disorder is characterized by a sudden onset of psychotic symptoms, which may include delusions, hallucinations, disorganized speech or behavior, or catatonic behavior. The symptoms must not be caused by schizophrenia, schizoaffective disorder, delusional disorder or mania in bipolar disorder. They must also not be caused by a drug (such as amphetamines) or medical condition (such as a brain tumor). The term bouffée délirante describes an acute nonaffective and nonschizophrenic psychotic disorder, which is largely similar to DSM-III-R and DSM-IV brief psychotic and schizophreniform disorders. Symptoms generally last at least a day, but not more than a month, and there is an eventual return to full baseline functioning. It may occur in response to a significant stressor in ones life, or in other situations where a stressor is ...
A decision-tree simulation model is used to examine the costs associated with olanzapine versus haloperidol in the treatment of patients with schizophrenia in the UK. Parameter values and outcome scores were derived mainly from an international clinical trial. Resource consequences were examined on the basis of assumed service delivery and actual unit costs specific to the UK. While olanzapine is more expensive to prescribe than haloperidol, it generates savings by reducing utilisation of medical services. As a result, a comparison of the 2 drugs is approximately cost neutral. Model uncertainties are examined using extensive sensitivity analysis; in most scenarios, cost-neutral results are maintained. Olanzapine is more effective than haloperidol as measured by Brief Psychiatric Rating Scale scores and non-relapse rates. With such gains in effectiveness and near equivalence in terms of costs, olanzapine, in comparison with haloperidol, may represent a cost-effective treatment option.. ...
Press conference at the 22nd Congress of the European College of Neuropsychopharmacology, Sept. 14, 2009, Istanbul, Turkey. Schizophrenia is a major public health problem. Affecting almost 1% of the worlds population, it takes an enormous economic and social toll in addition to the distress, dysfunction, disability and mortality for those afflicted with this disease. Elements of the disease are present from birth, other aspects emerge during developmental years, and the illness becomes fully expressed in early adulthood with long-lasting implications for most patients.. Schizophrenia, which is seen as the paradigmatic psychiatric illness, presents different symptoms in multiple domains, whereby positive and negative phenomena can be separated (Falkai et al., 2005): Positive (psychotic) symptoms in a broader sense include delusions or delusional ideation, hallucinations, disturbance of association, catatonic symptoms, agitations as well as feelings of alien influence and suspiciousness. Negative ...
By Dan Hoeweler. This article makes multiple false and misleading assumptions, one of which is the claim that people suffering from Schizophrenia and psychotic disorders are incapable of producing quality poetry due to the nature of their illness. I am a Certified Peer Specialist that suffers from Schizoaffective disorder and have written poetry that has been published in multiple magazines, psychology websites and street papers. If Dr Rothenbergs were correct in this highly prejudiced and inaccurate article then this would have never been the case. The author is selectively using examples of people writing poetry under psychotic duress in an attempt to prove his false claim. While it may be impossible to produce sensible poetry during a psychotic episode, there are times when a patient is lucid and able to rationalize their thoughts and ideas. During these times it is possible to produce poetry based upon the psychotic thought process. In fact I personally have found it therapeutic to do so, ...
TY - JOUR. T1 - Association of DNA methylation differences with schizophrenia in an epigenome-wide association study. AU - Montano, Carolina. AU - Taub, Margaret Anne. AU - Jaffe, Andrew. AU - Briem, Eirikur. AU - Feinberg, Jason I.. AU - Trygvadottir, Rakel. AU - Idrizi, Adrian. AU - Runarsson, Arni. AU - Berndsen, Birna. AU - Gur, Ruben C.. AU - Moore, Tyler M.. AU - Perry, Rodney T.. AU - Fugman, Doug. AU - Sabunciyan, Sarven. AU - Yolken, Robert H. AU - Hyde, Thomas. AU - Kleinman, Joel. AU - Sobell, Janet L.. AU - Pato, Carlos N.. AU - Pato, Michele T.. AU - Go, Rodney C.. AU - Nimgaonkar, Vishwajit. AU - Weinberger, Daniel. AU - Braff, David. AU - Gur, Raquel E.. AU - Fallin, Daniele Daniele. AU - Feinberg, Andrew P. PY - 2016/5/1. Y1 - 2016/5/1. N2 - Importance: DNA methylation may play an important role in schizophrenia (SZ), either directly as a mechanism of pathogenesis or as a biomarker of risk. O. Objective: To scan genome-wide DNA methylation data to identify differentially ...
In recent decades the community mental health movement has achieved a dramatic reduction in the census of state and county mental hospitals in the United States, and hundreds of federally-funded community mental health centers have been established nationwide. At the same time, national controversy has arisen in response to what in places has seemed the haphazard process of implementing "deinstitutionalization" and the fate of many chronically mentally ill persons who are without needed social services and psychological care. Despite the widespread attention that this contemporary program has received, theoretical analysis of the complex social, scientific, intellectual, and political origins of Americas community mental health policy remains deficient. This article examines the background and development of the Community Mental Health Centers Act of 1963, tracing how an important shift in national policy toward the mentally ill grew out of changing perceptions-among policymakers, professional ...
JL13 [5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5] benzoxazepine fumarate] is a substance with a close structural resemblance to clozapine. However, it is less sensitive to oxidation and may therefore have less hematological side effects. In the present study, JL13 was compared with clozapine and haloperidol in several animal models for schizophrenia. The paw test represents a screening model for antipsychotic drugs that can discriminate between drugs with extrapyramidal side effects and drugs without. Haloperidol increased both forelimb retraction time and hindlimb retraction time (HRT), whereas both clozapine and JL13 increased only HRT. In the prepulse inhibition paradigm, all three drugs reversed the apomorphine- and the amphetamine-induced disruption of prepulse inhibition. However, whereas haloperidol was equally effective against both dopaminergic drugs, JL13 and clozapine were more effective against amphetamine. Finally, only JL13 was able to increase prepulse inhibition in ...
Abstract [Full Text] [PDF]. Abstract [Article in Dutch]. In the Netherlands it has recently become possible for transsexual patients to receive hormonal treatment from the onset of puberty. Until the age of 16, pubertal development can be prevented with luteinizing hormone-releasing hormone (LHRH) agonists. From 16 years of age onwards, gender adjustment can be initiated by administration of hormones of the opposite sex. Surgical treatment can be offered once the patient reaches 18 years of age.. Although such treatment will only be initiated with reticence and after a long phase of intense diagnostic screening, the question arises whether a clear differentiation can be made between pure gender identity disorders and secondary transsexual feelings that are part of an ongoing psychopathological development, such as schizophrenia.. The potential diagnostic confusion is illustrated by a case history of a male schizophrenic patient. This patient had been treated hormonally for transsexualism for ...
title:Post Marketing Surveillance Study on Risperidone in Patients Suffering from Schizophrenia. Author:J R Zaveri, Vipul Chaudhari. Keywords:Post Marketing Surveillance, Risperidone, Schizophrenia. Type:Original Article. Abstract:Schizophrenia is one of the commonest psychiatric ailments. It has been estimated that approximately 1% of the population and 15% of the adults suffers from this disease. Risperidone, atypical antipsychotic, acts mainly by 5HT2 blockade action. Produce virtually no extra pyramidal side effects at low dose, has a broad efficacy. But extra pyramidal dysfunction can appear at higher doses. We conducted a post marketing surveillance study on risperidone in 40 patients suffering from schizophrenia at Psychiatric department of Civil Hospital, Ahmedabad. In this study we specially studied its efficacy and safety. The results of this study are consistent with phase III clinical studies on risperidone carried out in Indian patients except its effects on food intake. As far as ...
Dont go it alone. If youre an adult suffering with mental illness, change your future with help from the caring professionals at Appleseed Community Mental Health Center.. Mental health recover services. At Appleseed Community Mental Health Center, our caring professionals are invested in your success. We offer the following services and steps to recovery:. Mental Health Assessment: The first step in getting treatment for mental health involves an accurate assessment. Our clinicians will walk you through a thorough evaluation to determine what course of treatment is necessary and will best promote your success. Well look for areas of concern, set small goals that will move you forward on the recovery road, and get you functioning and able to enjoy life again, while emphasizing the strengths you have and positive things to come out of your growth.. Crisis Intervention: At any time during your treatment should you need immediate access to a counselor, you can call our crisis intervention ...
Sarasota, FL - (PRESS RELEASE JET) - 10/20/2017 - Global Tardive Dyskinesia (TD) Treatment Market: Overview. Tardive dyskinesia (TD) is a neurological disorder that has the involvement of the involuntary movements. The terms can be described as tardive which means delayed and dyskinesia which means abnormal movement. The symptoms of tardive dyskinesia include finger movement, facial grimacing, jaw swinging, repetitive chewing, continuous blinking of the eyes, tongue thrusting, and others. The side effect of the neuroleptics medicines is tardive dyskinesia. These medicines are also known as major tranquilizers or antipsychotics. These medicines are mainly used for treating mental issues. Tardive dyskinesia occurs when you are on the medication for many months or years. As the drug that can be used for the treatment of tardive dyskinesia is not approved and method of treatment is also yet not confirmed thus the treatment of the disease is a difficult task. The tardive dyskinesia treatment affects ...
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Persons with schizophrenia and related disorders may be particularly sensitive to a number of determinants of service use, including those related with illness, socio-demographic characteristics and organizational factors. The objective of this study is to identify factors associated with outpatient contacts at community mental health services of patients with schizophrenia or related disorders. This cross-sectional study analyzed 1097 patients. The main outcome measure was the total number of outpatient consultations during one year. Independent variables were related to socio-demographic, clinical and use of service factors. Data were collected from clinical records. The multilevel linear regression model explained 46.35% of the variance. Patients with significantly more contacts with ambulatory services were not working and were receiving welfare benefits (p = 0.02), had no formal education (p = 0.02), had a global level of severity of two or three (four being the most severe) (p < 0.001), with one
Diagnostic assessment of alcohol-induced psychotic disorders and delirium followed the guidelines of DSM-IV: a diagnosis of primary psychotic disorder was given if there was no evidence of heavy substance use or withdrawal, or if the psychotic symptoms were established before heavy substance use, or if the symptoms persisted for more than a month during a substance-free period. Alcohol-induced psychotic disorder was diagnosed only if a primary psychotic disorder had been ruled out. In alcohol-induced psychotic disorder, prominent psychotic symptoms occurred during or shortly after periods of heavy alcohol use. During these periods the psychotic symptoms were in excess of those usually associated with alcohol intoxication or withdrawal with perceptual disturbances, and severe enough to warrant clinical attention. To improve reliability the psychotic symptoms had to last at least 1 day, which is the minimum duration of brief psychotic disorder. The minimum duration of psychotic symptoms in ...
Question - How good is Homeopathy in treating Paranoid Schizophrenia very early stage? . Ask a Doctor about when and why Homeopathy is advised, Ask a Homeopath
Antipsychotics have at best small positive effects on cognitive performance. There is a lack of knowledge regarding the effects of antidepressants on cognitive functioning in these disorders. In the present study cognitive performance was investigated in relation to serum levels of antidepressants in persons with bipolar disorder and schizophrenia. Serum concentrations of escitalopram, citalopram and venlafaxine plus O-desmethylvenlafaxine were measured in a total of 187 participants with bipolar disorder (N = 74) or schizophrenia spectrum disorders (N = 113), and analyzed in relation to neuropsychological tests performance of verbal learning, verbal memory, attention, working memory, executive functioning and processing speed. Analyses were performed using linear regression adjusting for a range of confounders.. There was a significant positive association between the serum level of venlafaxine plus O-desmethylvenlafaxine and verbal memory (immediate recall: Logical Memory Test immediate recall ...
The major finding of this study is that inverse agonism at the h5-HT2C-INI receptor is not a reliable predictor of atypical antipsychotic activity. Additionally, several potent 5-HT2-family antagonists with equivocal (e.g., M100907, ritanserin) or no (isoclozapine, mianserin, amitriptyline) antipsychotic activity were found to be potent and effective inverse agonists at the h5-HT2C-INI receptor. These results indicate that inverse agonist activity at the h5-HT2C-INI receptor does not, by itself, reliably distinguish between typical and atypical antipsychotic drugs.. Several prior studies have described inverse agonist actions of typical and atypical antipsychotic drugs at 5-HT2C and 5-HT2A receptors (Barker et al., 1994; Westphal and Sanders-Bush, 1994; Labrecque et al., 1995; Egan et al., 1998;Herrick-Davis et al., 2000). Thus, Egan et al. (1998) were the first to systematically evaluate a large series of typical and atypical antipsychotic drugs for their inverse agonist actions at h5-HT2A ...
... James H. Johnson, Ph.D., ABPP University of Florida Pervasive Developmental Disorders: Old and New Labels • The current DSM IV category of Pervasive Developmental Disorders includes several more severe forms of child psychopathology. • Historically disorders of this type have been referred to by a variety of labels such as - - - - - atypical psychosis, child psychosis, symbiotic psychosis, childhood schizophrenia, and infantile autism Evolution in the Classification of PDD • Prior to 1980 and the development of DSM III. there was no adequate classification system for the diagnosis of these disorders. • In DSM II there was no category appropriate for more severe forms of child psychopathology apart from "Childhood Schizophrenia". • This category was very general and not sufficient for the diagnosis of the full range problems now considered under the heading of PDD DSM II Criteria for Childhood Schizophrenia • Symptoms appear before puberty. • The ...
Define tardive dyskinesia. tardive dyskinesia synonyms, tardive dyskinesia pronunciation, tardive dyskinesia translation, English dictionary definition of tardive dyskinesia. n. A chronic disorder of the nervous system characterized by involuntary jerky movements of the face, tongue, jaws, trunk, and limbs, usually caused by...
198 APPROACH TO THE PATIENT WITH PSYCHIATRIC SYMPTOMS Harrisons Manual of Medicine 198 APPROACH TO THE PATIENT WITH PSYCHIATRIC SYMPTOMS Major Psychiatric Disorders (Axis I Diagnoses) Mood Disorders (Major Affective Disorders) Schizophrenia and Other Psychotic Disorders Anxiety Disorders Personality Disorders (Axis Ii Diagnoses) Cluster A Personality Disorders Cluster B Personality Disorders Cluster C Personality Disorders…
BACKGROUND: The concept of dose equivalence is important for many purposes. The classical approach published by Davis in 1974 subsequently dominated textbooks for several decades. It was based on the assumption that the mean doses found in flexible-dose trials reflect the average optimum dose which can be used for the calculation of dose equivalence. We are the first to apply the method to second-generation antipsychotics. METHODS: We searched for randomized, double-blind, flexible-dose trials in acutely ill patients with schizophrenia that examined 13 oral second-generation antipsychotics, haloperidol, and chlorpromazine (last search June 2014). We calculated the mean doses of each drug weighted by sample size and divided them by the weighted mean olanzapine dose to obtain olanzapine equivalents. RESULTS: We included 75 studies with 16 555 participants. The doses equivalent to 1 mg/d olanzapine were: amisulpride 38.3 mg/d, aripiprazole 1.4 mg/d, asenapine 0.9 mg/d, chlorpromazine 38.9 mg/d, clozapine
Objective: To model the cost effectiveness of paliperidone palmitate (paliperidone long-Acting injectable; PLAI), a new once-monthly long-Acting antipsychotic therapy, compared with risperidone long-Acting injectable (RLAI) and olanzapine pamoate (OLAI), in multi-episode patients (two or more relapses) with schizophrenia in Sweden. Methods: A Markov decision analytic model was developed to simulate the history of a cohort of multi-episode patients transitioning through different health states on a monthly basis over a 5-year time horizon from the perspective of the Swedish healthcare system. Therapeutic strategies consisted of starting treatment with RLAI (mean dose 37.5mg every 2 weeks), PLAI (mean dose 75mg equivalent (eq.) every month) or OLAI (150mg every 2 weeks or 300mg every 4 weeks). Probability of relapse, level of adherence, side-effects (extrapyramidal symptoms, tardive dyskinesia, weight gain and diabetes) and treatment discontinuation (switch) were derived from long-term ...
What Is RFC?. When schizophrenia is not severe enough to meet or equal a listing at Step 3 of the Sequential Evaluation Process, the Social Security Administration will need to determine residual functional capacity (RFC) to decide whether the claimant is disabled at Step 4 and Step 5 of the Sequential Evaluation Process. RFC is a claimants ability to perform work-related activities. In other words, it is what you can still do despite your limitations.. Mental RFC. An RFC for mental impairments is expressed in terms of whether Social Security Administration believes the claimant can do skilled, semi-skilled, or unskilled work in spite of impairments, or whether the claimant cannot even do unskilled work.. Denial Is Likely for RFCs for Unskilled Work or Better. Claimants with a mental RFC for the ability to perform unskilled work who have no physical impairments will almost always be denied Social Security disability benefits. Rare exceptions are claimants with no more than a limited education, ...
What Is RFC?. When schizophrenia is not severe enough to meet or equal a listing at Step 3 of the Sequential Evaluation Process, the Social Security Administration will need to determine residual functional capacity (RFC) to decide whether the claimant is disabled at Step 4 and Step 5 of the Sequential Evaluation Process. RFC is a claimants ability to perform work-related activities. In other words, it is what you can still do despite your limitations.. Mental RFC. An RFC for mental impairments is expressed in terms of whether Social Security Administration believes the claimant can do skilled, semi-skilled, or unskilled work in spite of impairments, or whether the claimant cannot even do unskilled work.. Denial Is Likely for RFCs for Unskilled Work or Better. Claimants with a mental RFC for the ability to perform unskilled work who have no physical impairments will almost always be denied Social Security disability benefits. Rare exceptions are claimants with no more than a limited education, ...
TY - JOUR. T1 - A longitudinal study of correlations among tardive dyskinesia, drug- induced parkinsonism, and psychosis. AU - Hansen, Thomas. AU - Weigel, R. M.. AU - Brown, W. L.. AU - Hoffman, W. F.. AU - Casey, Daniel. PY - 1992. Y1 - 1992. N2 - Tardive dyskinesia (TD) and drug-induced parkinsonism (DIP) have been hypothesized to reflect opposing states of dopamine (DA) function. In this longitudinal study, 57 psychotic inpatients were rated repeatedly for TD, DIP, and psychosis while receiving neuroleptic medication. Cross-sectional correlations among TD, DIP, and psychosis were weak or nonexistent. Factor and cluster analyses found that 13 patients (23%) were classified into groups characterized by the expected negative correlations. Thus, only partial support was found for the hypothesis that TD and DIP represent opposing states of DA function.. AB - Tardive dyskinesia (TD) and drug-induced parkinsonism (DIP) have been hypothesized to reflect opposing states of dopamine (DA) function. In ...
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Purpose: Clozapine is a well-known antipsychotic medication licensed for treatment-resistant schizophrenia, but there is limited research available to suggest its efficacy in the context of personality disorder and intellectual disabilities presenting with high-risk behaviour with or without psychotic symptoms. The purpose of this paper is to raise awareness of the benefits of using clozapine in patients with intellectual disabilities and personality disorder that present with a complex picture of serious risk of harm to both their life and the lives of others. Design/methodology/approach: The authors present five patients with intellectual disabilities and serious life-threatening challenging behaviour whom were started on clozapine as part of their multidisciplinary treatment plan to manage their presentation. The authors completed baseline assessment of five main symptom domains and then repeated this assessment following treatment with clozapine. Findings: In all five cases use of clozapine ...
This study examined the roles of posttraumatic stress (PTS) symptoms and dissociation in the relationship between childhood trauma and two different types of psychosis-like experience, including persecutory ideation and aberrant experience, in non-psychotic psychiatric patients. From August 2015 to August 2016, among psychiatric out patients seeking treatment at the Department of Psychiatry at a major teaching medical hospital in Seoul, Korea, 169 patients who had never been diagnosed with a psychotic disorder, including schizophrenia spectrum disorder, bipolar disorder, and/or depressive disorder with psychotic features, completed the Korean Childhood Trauma Questionnaire, the Korean version of the Impact of Event Scale-Revised, the modified Korean version of the Peritraumatic Dissociation Experiences Questionnaire, and the Korean Minnesota Multiphasic Personality Inventory-2 (MMPI-2 ...
Thioridazine (Mellaril or Melleril) is a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis. The branded product was withdrawn worldwide in 2005 because it caused severe cardiac arrhythmias. However, generic versions are still available in the US. Thioridazine was voluntarily discontinued by its manufacturer, Novartis, worldwide because it caused severe cardiac arrhythmias. Its primary use in medicine was the treatment of schizophrenia. It was also tried with some success as a treatment for various psychiatric symptoms seen in people with dementia, but chronic use of thioridazine and other anti-psychotics in people with dementia is not recommended. For further information see: Phenothiazine Thioridazine prolongs the QTc interval in a dose-dependent manner. It produces significantly less extrapyramidal side effects than most first-generation antipsychotics. Its use, along with the use of ...
Aims To assess if cannabis use is a risk factor for future psychotic symptoms, and vice versa, in adolescents and young adults from the general population.. Design Cohort study.. Setting/participants Zuid Holland study, a 14-year follow-up study of 1580 initially 4-16-year-olds who were drawn randomly from the Dutch general population. Because cannabis use is generally condoned in the Netherlands, false-negative reports of cannabis use may occur less frequently than in countries with stricter drug policies, which supports the value of the present study.. Measurements Life-time cannabis use and psychotic symptoms, assessed with the Composite International Diagnostic Interview (CIDI).. Findings Cannabis use, in individuals who did not have psychotic symptoms before they began using cannabis, predicted future psychotic symptoms (hazard ratio = 2.81; 95% confidence interval = 1.79-4.43). However, psychotic symptoms in those who had never used cannabis before the onset of psychotic symptoms also ...
Clinical obervations indicate that antipsychotic action starts early and increases in magnitude with repeated treatment. Animal models that faithfully capture this time course of action are few. Inhibition of hyperlocomotion induced by amphetamine or phencyclidine has been widely used as a screening tool for the antipsychotic activity of a drug. We thus investigated whether repeated antipsychotic treatment could produce an early-onset and progressively increased antagonistic effect on amphetamine or phencyclidine-induced hyperlocomotion as a way of assessing the validity of such models in capturing time course of antipsychotic action. One each of the five consecutive test days, different groups of rats (n = 6-7/group) received an initial injection of either haloperidol (0.01-0.10 mg/kg, sc), clozapine (5-20.0 mg/kg, sc), olanzapine (1.0 mg/kg, sc), chlordiazepoxide (10.0 mg/kg, ip) or vehicle (sterile water, sc) 30 min prior to a second injection of either amphetamine (1.5 mg/kg, sc) or phencyclidine (3
The new Metabolic Monitoring for Children and Adolescents on Antipsychotics (APM) HEDIS measure calculates the percentage of children ages 1-17 who have had two or more antipsychotic prescriptions filled and at least one metabolic test for blood glucose HbA1c, and at least one test for low-density lipoprotein cholesterol (LCL-C) or total cholesterol each year. Examples of first and second-generation antipsychotic medications included in this measure are chlorpromazine, aripiprazole, clozapine, olanzapine, risperidone, haloperidol, and trifluoperazine. As you know, while antipsychotic medications are effective in treating certain mental illnesses in children, their side effects can lead to or exacerbate other health problems. Children taking antipsychotics are prone to significant weight gain and obesity-related complications such as cardiovascular issues, hypertension, hypercholesterolemia, and insulin-resistant type 2 diabetes. Consequently, it is important that patients on antipsychotic ...
Rob Wolf Bruce Neben Ryan Melton http://www.iepa.org.au  Dropping Schizophrenia subtypes    Adding Psychosis Risk Syndromes    Includes shared psychotic disorder Adds catatonia specifier Attenuated Psychotic Symptoms Syndrome Moving away from "prodrome". http://www.dsm5.org/Pages/Default.aspx  Aims  Rule out past and current psychosis  POPS (presence of psychotic symptoms at 6 on SOPS- scale of psychosis risk syndromes.  Rule in one or more of 3 types of At risk syndromes  BIPS (Brief Intermittent Psychotic State)  Attenuated Positive Symptom State (APSS)  Genetic Risk & Deterioration (GRD) Rate severity of current at risk syndromes.  Major changes   Rule out criteria emphasized  Emphasis on more objective GAF.    1 year RCT of 10 sites with 1268 individuals (China). Tx group received meds, family psychoeducation (not mfg), skills training, CBT. Outcomes:   Tx group lower drop out Tx group greater improvement in insight, social ...
Despite advances in the treatment of severe, prolonged psychotic illnesses such as schizophrenia, many if not most patients continue to suffer from residual symptoms, episodic relapses, and significant deficits in psychosocial functioning and well-being.. While mindfulness-based interventions (MBIs) have been of some proven value in the treatment of affective and anxiety disorders, clinicians are often reluctant to employ MBIs for patients with psychotic disorders due to fear that focusing awareness in the context of hallucinations and delusions might exacerbate symptoms of the illness.. Chien and Thompson [British Journal of Psychiatry] conducted a randomized, controlled multisite trial of an MBI with 107 Chinese schizophrenic outpatients in Hong Kong. Patients were assigned to either a Mindfulness-Based Psychoeducation Program (MBPP), a conventional psychoeducation program (CPP), or treatment as usual (TAU) that consisted of monthly psychiatric outpatient clinic visits and access to a variety ...
Behavioral evidence indicates that working memory (WM) in schizophrenia is already impaired at the encoding stage. However, the neurophysiological basis of this primary deficit remains poorly understood. Using event-related fMRI, we assessed differences in brain activation and functional connectivity during the encoding, maintenance and retrieval stages of a visual WM task with 3 levels of memory load in 17 adolescents with early-onset schizophrenia (EOS) and 17 matched controls. The amount of information patients could store in WM was reduced at all memory load levels. During encoding, activation in left ventrolateral prefrontal cortex (VLPFC) and extrastriate visual cortex, which in controls positively correlated with the amount of stored information, was reduced in patients. Additionally, patients showed disturbed functional connectivity between prefrontal and visual areas. During retrieval, right inferior VLPFC hyperactivation was correlated with hypoactivation of left VLPFC in patients ...
The purposes of this study were to evaluate patients with low-back pain (LBP) and leg pain due to magnetic resonance imaging-confirmed disc herniation who are treated with high-velocity, low-amplitude spinal manipulation in terms of their short-, medium-, and long-term outcomes of self-reported global impression of change and pain levels at various time points up to 1 year and to determine if outcomes differ between acute and chronic patients using a prospective, cohort design. A large percentage of acute and importantly chronic lumbar disc herniation patients treated with chiropractic spinal manipulation reported clinically relevant improvement. Significant improvement for all outcomes at all time points was reported. At 3 months, 90.5% of patients were "improved" with 88.0% "improved" at 1 year. Although acute patients improved faster by 3 months, 81.8% of chronic patients reported "improvement" with 89.2% "improved" at 1 year. There were no adverse events reported.. The specific lumbar spinal ...
article{7086173, abstract = {Background: Pharmacological cognitive enhancement, using chemicals to change cellular processes in the brain in order to enhance ones cognitive capacities, is an often discussed phenomenon. The prevalence among Dutch university students is unknown. Methods: The study set out to achieve the following goals: (1) give an overview of different methods in order to assess the prevalence of use of prescription, illicit and lifestyle drugs for cognitive enhancement (2) investigate whether polydrug use and stress have a relationship with cognitive enhancement substance use (3) assessing opinions about cognitive enhancement prescription drug use. A nationwide survey was conducted among 1572 student respondents of all government supported Dutch universities. Results: The most detailed level of analysis use of specific substances without a prescription and with the intention of cognitive enhancement shows that prescription drugs, illicit drugs and lifestyle drugs are ...
Persecutory delusions are one of the most common and distressing symptoms of psychosis. Many studies indicate an association of persecutory delusions with depression. A direct role for depression-related cognitive factors in the maintenance of persecutory delusions has not been systematically examined, despite such processes being implicated in a cognitive model. To determine whether depression in people with persecutory delusions is associated with the same cognitive factors implicated in major depressive disorder, and to examine these factors as predictors of the persistence of persecutory delusions over time. A systematic literature review formed the basis of two linked studies: one cross-sectional and one longitudinal. In the first study, 60 participants with persecutory delusions and schizophrenia spectrum diagnoses were classified into two groups, according to whether or not they met ICD-10 criteria for major depression. Assessments were made of delusions, depression and key cognitive ...
Endophenotypes (intermediate phenotypes) are objective, heritable, quantitative traits hypothesized to represent genetic risk for polygenic disorders at more biologically tractable levels than distal behavioural and clinical phenotypes. It is theorized that endophenotype models of disease will help to clarify both diagnostic classification and aetiological understanding of complex brain disorders such as obsessive-compulsive disorder (OCD). To investigate endophenotypes in OCD, we measured brain structure using magnetic resonance imaging (MRI), and behavioural performance on a response inhibition task (Stop-Signal) in 31 OCD patients, 31 of their unaffected first-degree relatives, and 31 unrelated matched controls. Both patients and relatives had delayed response inhibition on the Stop-Signal task compared with healthy controls. We used a multivoxel analysis method (partial least squares) to identify large-scale brain systems in which anatomical variation was associated with variation in ...
On August 22, 2007, Risperdal was approved as the only drug agent available for treatment of schizophrenia in youth ages 13 17; it was also approved that same day for treatment of bipolar disorder in youth and children ages 10 17, joining lithium. Risperidone contains the functional groups of benzisoxazole and piperidine as part of its molecular structure. In 2003 the FDA approved risperidone for the short-term treatment of the mixed and manic states associated with bipolar disorder. In 2006 the FDA approved risperidone for the treatment of irritability in children and adolescents with autism. The FDA`s decision was based in part on a study of autistic children with severe and enduring problems of violent meltdowns, aggression, and self-injury; risperidone is not recommended for autistic children with mild aggression and explosive behavior without an enduring pattern. Like other atypical antipsychotics, risperidone has also been used off-label for the treatment of anxiety disorders, such as ...
On August 22, 2007, Risperdal was approved as the only drug agent available for treatment of schizophrenia in youth ages 13 17; it was also approved that same day for treatment of bipolar disorder in youth and children ages 10 17, joining lithium. Risperidone contains the functional groups of benzisoxazole and piperidine as part of its molecular structure. In 2003 the FDA approved risperidone for the short-term treatment of the mixed and manic states associated with bipolar disorder. In 2006 the FDA approved risperidone for the treatment of irritability in children and adolescents with autism. The FDA`s decision was based in part on a study of autistic children with severe and enduring problems of violent meltdowns, aggression, and self-injury; risperidone is not recommended for autistic children with mild aggression and explosive behavior without an enduring pattern. Like other atypical antipsychotics, risperidone has also been used off-label for the treatment of anxiety disorders, such as ...
0041] In a preferred embodiment the compounds of the present invention may be useful for the treatment, prevention or alleviation of a cognitive disorder, learning deficit, memory deficits and dysfunction, Downs syndrome, Alzheimers disease, attention deficit, attention deficit hyperactivity disorder (ADHD), Tourettes syndrome, psychosis, depression, Bipolar Disorder, mania, manic depression, schizophrenia, cognitive or attention deficits related to schizophrenia, obsessive compulsive disorders (OCD), panic disorders, eating disorders such as anorexia nervosa, bulimia and obesity, narcolepsy, nociception, AIDS-dementia, senile dementia, autism, Parkinsons disease, Huntingtons disease, Amyotrophic Lateral Sclerosis, anxiety, non-OCD anxiety disorders, convulsive disorders, epilepsy, neurodegenerative disorders, transient anoxia, induced neuro-degeneration, neuropathy, diabetic neuropathy, peripheral dyslexia, tardive dyskinesia, hyperkinesia, mild pain, moderate or severe pain, pain of ...
New York, New York (PRWEB) August 19, 2014 -- As Risperdal lawsuits (www.risperdallawsuitcenter.com) mount in U.S. courts, Bernstein Liebhard LLP notes the
It is indicated for the treatment of schizophrenia; acute manic or mixed episodes in bipolar I disorder. Lupin has launched Quetiapine Fumarate extended-release tablets, 50 mg, 150 mg, 200 mg, 300 mg and 400 mg having received an approval from the United States Food and Drug Administration (FDA) earlier.. Lupins Quetiapine Fumarate extended-release tablets, 50 mg, 150 mg, 200 mg, 300 mg and 400 mg are the AB rated generic equivalent of AstraZeneca Pharmaceuticals LPs Seroquel XR Tablets, 50 mg, 150 mg, 200 mg, 300 mg and 400 mg. It is indicated for the treatment of schizophrenia; acute manic or mixed episodes in bipolar I disorder alone or as an adjunct to lithium or divalproex; acute depressive episodes in bipolar disorder; maintenance treatment of bipolar I disorder, as an adjunct to lithium or divalproex and as an adjunctive therapy to antidepressants for the treatment of major depressive disorder. ...
BACKGROUND: Psychosis onset is characterized by white matter and electrophysiologic abnormalities. The relation between these factors in the development of illness is almost unknown. We studied the relation between white matter volumes and P300 in prodromal psychosis. METHODS: We assessed white matter volume (detected using magnetic resonance imaging) and electrophysiologic response during an oddball task (P300) in healthy controls and individuals at high clinical risk for psychosis (with an at-risk mental state [ARMS]). RESULTS: We included 41 controls and 39 patients with an ARMS in our study. A psychotic disorder developed in 26% of the ARMS group within the follow-up period of 2 years. The P300 amplitude was significantly lower in the ARMS group than in the control group. The ARMS group showed reduced volume of white matter underlying the left superior temporal gyrus and the left superior frontal gyrus and increased volume of white matter underlying the right insula and the right angular gyrus
In a study published in online journal npj Schizophrenia, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of subjects with schizophrenia or bipolar disorder than in those without these disorders.. The researchers caution that their findings do not establish a cause-and-effect relationship between mental illness and yeast infections, but may support a more detailed examination into the role of lifestyle, immune system weaknesses and gut-brain connections as contributing factors to the risk of psychiatric disorders. "Its far too early to single out Candida infection as a cause of mental illness or vice versa," says Emily Severance, assistant professor of pediatrics and member of the Stanley Division of Developmental Neurovirology at the Johns Hopkins University School of Medicine.. Candida albicans is a yeast-like fungus naturally found in small amounts in human digestive tracts, but its overgrowth in warm, moist environments causes burning, ...

Influence of Auditory Stimulation Rates on Evoked Potentials during General Anesthesia:Relation between the Transient Auditory...Influence of Auditory Stimulation Rates on Evoked Potentials during General Anesthesia:Relation between the Transient Auditory...

... the auditory middle-latency response and (2) the 40-Hz auditory steady state response (ASSR). (1) The auditory middle-latency ... AUDITORY evoked potentials consist of electrical activity in the brain that is linked to (or evoked from) auditory stimuli. Two ... Influence of Auditory Stimulation Rates on Evoked Potentials during General Anesthesia: Relation between the Transient Auditory ... Influence of Auditory Stimulation Rates on Evoked Potentials during General Anesthesia: Relation between the Transient Auditory ...
more infohttps://anesthesiology.pubs.asahq.org/article.aspx?articleid=1923799

Role of cervical vestibular evoked myogenic potentials (cVEMP) and auditory brainstem response (ABR) in the evaluation of...Role of cervical vestibular evoked myogenic potentials (cVEMP) and auditory brainstem response (ABR) in the evaluation of...

Role of cervical vestibular evoked myogenic potentials (cVEMP) and auditory brainstem response (ABR) in the evaluation of ... Role of cervical vestibular evoked myogenic potentials (cVEMP) and auditory brainstem response (ABR) in the evaluation of ... Clinical study of vestibular-evoked myogenic potentials and auditory brainstem responses in patients with brainstem lesions ... May - June 2017 Role of cervical vestibular evoked myogenic potentials (cVEMP) and auditory brai... ...
more infohttp://rborl.org.br/en-role-cervical-vestibular-evoked-myogenic-articulo-S1808869416300672

Plus itPlus it

Auditory evoked response potentials.. Mice were presented with a continuous stimulus train consisting of 6 kHz tones (0.5 s ... leading to a reduction in the amplitude of auditory evoked response potentials (ERPs). One hypothesis is that this process, ... 2012) Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials. PLoS One 7:e39775. doi:10.1371 ... 2009) Engaging in an auditory task suppresses responses in auditory cortex. Nat Neurosci 12:646-654. doi:10.1038/nn.2306 pmid: ...
more infohttp://www.jneurosci.org/content/38/10/2569

Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia - Full Text View - ClinicalTrials.govSafety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia - Full Text View - ClinicalTrials.gov

P50 auditory evoked potential response (amplitude measured in microvolts) using sensory gating paradigm. Measured by EEG as ... P300 auditory evoked potential response (amplitude in microvolts) using orienting paradigm. Measured by EEG and calculated as ... N100 auditory evoked potential response (amplitude measured in microvolts) using the sensory gating paradigm. Measured by ... Mismatch negativity (MMN) auditory evoked potential response (amplitude in microvolts) using orienting paradigm. Measured by ...
more infohttps://clinicaltrials.gov/ct2/show/NCT01556763

Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia - Tabular View - ClinicalTrials.govSafety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia - Tabular View - ClinicalTrials.gov

P50 auditory evoked potential response (amplitude measured in microvolts) using sensory gating paradigm. Measured by EEG as ... P300 auditory evoked potential response (amplitude in microvolts) using orienting paradigm. Measured by EEG and calculated as ... N100 auditory evoked potential response (amplitude measured in microvolts) using the sensory gating paradigm. Measured by ... Mismatch negativity (MMN) auditory evoked potential response (amplitude in microvolts) using orienting paradigm. Measured by ...
more infohttps://clinicaltrials.gov/ct2/show/record/NCT01556763?term=evp-6124&rank=8

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His visual and brain stem auditory evoked response potentials were abnormal. Other laboratory studies, including serum amino ... His auditory and visual somatosensory evoked potentials were normal, as were his laboratory results for serum amino acids and ... His auditory and visual somatosensory evoked potentials were normal. Laboratory results for serum amino acids were normal, ...
more infohttp://www.ajnr.org/content/24/8/1683

Human Rabies --- Minnesota, 2007Human Rabies --- Minnesota, 2007

Auditory evoked potential testing indicated absent responses. With the presumptive diagnosis of idiopathic transverse myelitis ... Once rabies was suspected, the patients family was interviewed on October 16 for a history of potential exposure. According to ... Health and CDC and the ensuing public health response. The findings underscore the need for early inclusion of rabies in the ... potential exposures. Prompt diagnosis of rabies can enable rapid case investigation, implementation of appropriate infection- ...
more infohttps://www.cdc.gov/mmwr/preview/mmwrhtml/mm5717a3.htm

Muthusamy A[au] - PubMed - NCBIMuthusamy A[au] - PubMed - NCBI

Mid-latency auditory evoked potential response revealed as an evidence of neural plasticity in blinnd individuals. ... In vitro culture responses, callus growth and organogenetic potential of brinjal (Solanum melongena L.) to He-Ne laser ... Responses of He-Ne laser irradiation on agronomical characters and chlorogenic acid content of brinjal (Solanum melongena L.) ... Responses to mechanically and visually cued water waves in the nervous system of the medicinal leech. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Muthusamy+A%5Bau%5D&dispmax=50

Recovery from prior stimulation. I: Relationship to spontaneous firing rates of primary auditory neurons - Semantic ScholarRecovery from prior stimulation. I: Relationship to spontaneous firing rates of primary auditory neurons - Semantic Scholar

We find that for low spontaneous-rate neurons, peak onset responses increase in magnitude over a longer range of interstimulus ... Recovery of neural thresholds following a forward masker was measured for auditory neurons in anesthetized chinchillas. We find ... Computational modeling of the human auditory periphery: Auditory-nerve responses, evoked potentials and hearing loss. *Sarah ... Basic response properties of auditory nerve fibers: a review. *Peter Heil, Adam J. Peterson ...
more infohttps://www.semanticscholar.org/paper/Recovery-from-prior-stimulation.-I%3A-Relationship-to-Relkin-Doucet/fb51aaee58af92f6e3dcc520458a445c2e2c5886

The Open Biomedical Engineering Journal - Home PageThe Open Biomedical Engineering Journal - Home Page

Auditory Evoked Potential Response and Hearing Loss: A Review M. P Paulraj, Kamalraj Subramaniam , Sazali Bin Yaccob , Abdul H ... exhibiting mainly nonlinear hyperelastic type of response. The mechanical response of arteries depends on the health of tissues ... Natural Sensations Evoked in Distal Extremities Using Surface Electrical Stimulation Julia P. Slopsema, John M. Boss, Lane A. ... The Effect of Strain Hardening on the Dynamic Response of Human Artery Segments. When subjected to time-dependent blood ...
more infohttps://openbiomedicalengineeringjournal.com/

CG-MED-49 Auditory Brainstem Responses (ABRs) and Evoked Otoacoustic Emissions (OAEs) for Hearing DisordersCG-MED-49 Auditory Brainstem Responses (ABRs) and Evoked Otoacoustic Emissions (OAEs) for Hearing Disorders

Auditory Evoked Potential (AEP). Brainstem Auditory Evoked Potential (BAEP). Brainstem Auditory Evoked Response (BAER). ... ABR is also referred to as auditory evoked response (AER), auditory evoked potential (AEP), evoked auditory potential (EAP), ... ABR is also referred to as auditory evoked response (AER) auditory evoked potential (AEP), brainstem evoked auditory potential ... EAP), brainstem auditory evoked potential (BAEP), brainstem auditory evoked response (BAER), and evoked response audiometry. ...
more infohttps://www.unicare.com/medicalpolicies/guidelines/gl_pw_c160719.htm

suction screeningsuction screening

A Portable Auditory Steady-State Response Evoked Potentials…. The screening of stranded or rehabilitated aquatic mammals ... auditory ... by skin-contact using a polyurethane suction cup or an acoustically transparent cushion... ...
more infohttp://www.migracion-ue-alc.eu/crusher/7049/suction-screening.html

Plus itPlus it

We thus examined whether the auditory responses (evoked-potentials associated with stimulus onset) were predictive of the ... Auditory stimuli in REM sleep also evoked archetypal potentials: a positivity ∼200 ms followed by a negativity ∼500 ms (Fig. 7a ... Auditory evoked potentials are predictive of motor preparation in REM sleep. We applied the same approach to REM sleep. ... In NREM sleep, brain responses to stimuli were characterized by strong evoked potentials, such as the P200 and the N550 (Fig. 6 ...
more infohttp://www.jneurosci.org/content/36/24/6583

Combination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral RetinoblastomaCombination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral Retinoblastoma

Recording of evoked potentials by auditory brain stem response. PRIOR CONCURRENT THERAPY:. Biologic therapy. - Not specified. ... Meets 1 of the following auditory criteria:. - Normal audiogram. - At least normal responses to speech by audiogram. - ...
more infohttp://www.knowcancer.com/cancer-trials/NCT00110110/

Publications List (L-M)Publications List (L-M)

... apparent source of the auditory p300 evoked response potential. Alcohol, 7(5), 471-477. (02.11). Lutfy, K., & Weber, E. (1998 ...
more infohttp://uclaisap.org/publications/pubs-l-m.html

Can anyone explain this?  - Neurology - MedHelpCan anyone explain this? - Neurology - MedHelp

These are visual evoked potentials, brain stem auditory evoked response, and somatosensory evoked potential. Slower nerve ... These are visual evoked potentials, brain stem auditory evoked response, and somatosensory evoked potential. Slower nerve ... auditory, or sensory experience. Mine was...you guessed it: headaches. The epilepsy doesnt factor into my life anymore, but ... auditory, or sensory experience. Mine was...you guessed it: headaches. The epilepsy doesnt factor into my life anymore, but ...
more infohttp://www.medhelp.org/posts/Neurology/Can-anyone-explain-this-/show/1186081

Brain mri - Neurology - MedHelpBrain mri - Neurology - MedHelp

These are visual evoked potentials, brain stem auditory evoked response, and somatosensory evoked potential. Slower nerve ... These are visual evoked potentials, brain stem auditory evoked response, and somatosensory evoked potential. Slower nerve ... responses in any one of these is not confirmatory of MS but can be used to complement diagnosis along with a neurological ... responses in any one of these is not confirmatory of MS but can be used to complement diagnosis along with a neurological ...
more infohttp://www.medhelp.org/posts/Neurology/Brain-mri/show/1480875

Stent-Assisted Coiling Versus Balloon Remodeling of Wide-Neck Aneurysms: Comparison of Angiographic Outcomes | American Journal...Stent-Assisted Coiling Versus Balloon Remodeling of Wide-Neck Aneurysms: Comparison of Angiographic Outcomes | American Journal...

... continuous neurophysiologic monitoring including somatosensory evoked potentials, brain stem auditory-evoked responses, and ... Because of the potential flow-remodeling effects of self-expanding stents, we may tend to achieve lower packing densities in ... Because of this potential flow-remodeling effect of self-expanding stents, we generally avoid overpacking stented aneurysms and ... Flow diversion and flow disruption are potential alternatives in the treatment of wide-neck intracranial aneurysms. In a large ...
more infohttp://www.ajnr.org/node/12649.full.print

The Fixation Suppression Test in ENG Evaluation Kamran Barin Vestibular Issues and Balance Disorders Electrophysiology 949The Fixation Suppression Test in ENG Evaluation Kamran Barin Vestibular Issues and Balance Disorders Electrophysiology 949

Evoked Potentials Part 3: Auditory Steady State Response. Presented by Wendy Crumley, MS, CCC-A. ... www.audiologyonline.com/audiology-ceus/course/evoked-potentials-part-3-auditory-878 Evoked Potentials Part 3: Auditory Steady ... ocular vestibular evoked myogenic potential, and subjective visual vertical as tests of saccular and utricular function. ... ocular vestibular evoked myogenic potential, and subjective visual vertical as tests of saccular and utricular function. ...
more infohttps://www.audiologyonline.com/articles/fixation-suppression-test-in-eng-949

Basis of Intraoperative Neurophysiological Monitoring | Springer for Research & DevelopmentBasis of Intraoperative Neurophysiological Monitoring | Springer for Research & Development

Deep Brain Stimulation Visual Evoke Potential Auditory Brainstem Response Compound Action Potential Surgical Manipulation These ... Grundy B (1983) Intraoperative monitoring of sensory evoked potentials. Anesthesiology 58:72-87.CrossRefPubMedGoogle Scholar ... Raudzens PA (1982) Intraoperative monitoring of evoked potentials. Ann. N. Y. Acad. Sci. 388:308-26.CrossRefPubMedGoogle ... Grundy B (1985) Evoked potentials monitoring, in Monitoring in Anesthesia and Critical Care Medicine, C Blitt, Editor. ...
more infohttps://rd.springer.com/chapter/10.1007/978-1-4419-7436-5_2

Professor Robert Allen | Engineering | University of SouthamptonProfessor Robert Allen | Engineering | University of Southampton

Recording the middle latency response of the auditory evoked potential as a measure of depth of anaesthesia. A technical note. ... Bell, S. L., Smith, D. C., Allen, R., & Lutman, M. E. (2006). The auditory middle latency response, evoked using maximum length ... Particular interests include: cooperative behaviour, echolocation, the efficient estimation of auditory evoked potentials for ... Bell, S. L., Allen, R., & Lutman, M. E. (2001). The use of band-limited chirp stimuli to elicit the Auditory Brainstem Response ...
more infohttps://www.southampton.ac.uk/engineering/about/staff/ra.page

DE3821970C1 -  - Google PatentsDE3821970C1 - - Google Patents

Cortical, auditory, evoked potentials in response to changes of spectrum and amplitude. ... Excitatory and inhibitory response areas of auditory neurons in the cochlear nucleus. ... Auditory prosthesis CA2740877C (en) * 2008-10-15. 2015-02-03. Med-El Elektromedizinische Geraete Gmbh. Inner ear drug delivery ... Auditory stimulation using CW and pulsed signals Family Cites Families (12). * Cited by examiner, † Cited by third party. ...
more infohttps://patents.google.com/patent/DE3821970C1/en

The AMEDEO Literature GuideThe AMEDEO Literature Guide

Auditory brain stem response and cortical evoked potentials in children with type 1 diabetes mellitus.. Acta Otolaryngol. 2016. ... Speech-evoked auditory brainstem response with ipsilateral noise in adults with unilateral hearing loss.. Acta Otolaryngol. ... Revision of a furosemide-loading vestibular-evoked myogenic potential protocol for detecting endolymphatic hydrops.. Acta ... Pathological eye movements influence on the recordings of ocular vestibular-evoked myogenic potential.. Acta Otolaryngol. 2017; ...
more infohttp://amedeo.com/medicine/orl/actaolar.htm

PET Scanning in Autism Spectrum Disorders: Overview, Evaluation of Autism Spectrum Disorders, Screening for PET ScanningPET Scanning in Autism Spectrum Disorders: Overview, Evaluation of Autism Spectrum Disorders, Screening for PET Scanning

Auditory cognitive evoked potentials recorded in response to common and rare tones (P300) of an 8-year-old boy with autistic ... visual evoked potentials (VEPS), cortical auditory evoked potentials (CAEPs), auditory cognitive evoked potentials (P300), and ... Auditory cognitive evoked potentials recorded in response to common and rare tones (P300) of an 8-year-old boy with autistic ... The image below illustrates the same childs normal auditory cognitive evoked potentials recorded in response to common and ...
more infohttps://emedicine.medscape.com/article/1155568-overview
  • 21 This prediction discrepancy during anesthesia has lead to several hypotheses evoking a stimulation rate-dependent property of anesthetic action 21 or an adaptation of the auditory apparatus. (asahq.org)
  • These modulations are tracked using classic event-related potential analyses complemented by Lempel-Ziv complexity (LZc), a measure shown to track arousal in sleep and anesthesia. (jneurosci.org)
  • Grundy B (1985) Evoked potentials monitoring, in Monitoring in Anesthesia and Critical Care Medicine , C Blitt, Editor. (springer.com)
  • Awake craniotomy for assisting placement of auditory brainstem implant in NF2 patients. (amedeo.com)
  • Alteration of auditory function in type 2 diabetic and pre-diabetic patients. (amedeo.com)
  • This study will evaluate the safety of a potential new treatment for patients with certain IMDs known to benefit from HSCT using allogeneic UCB donor cells. (clinicaltrials.gov)
  • Although patients appear and feel completely deaf, they can still exhibit some reflex responses such as turning their head towards a loud sound. (wikipedia.org)
  • Patients with auditory agnosia can be unaware of their deficit, and insist that they are not deaf. (wikipedia.org)
  • The potential effect of human chorionic gonadotropin on vasoproliferative disorders of the immature retina. (nih.gov)
  • Caloric responses usually reach their peak approximately 30 seconds after the irrigation ends (60-90 seconds from the onset of the irrigation depending on whether water or air irrigations are used). (audiologyonline.com)
  • The FFR can be evoked to sinusoids, complex tones, steady-state vowels, tonal sweeps, or consonant-vowel syllables. (wikipedia.org)
  • Most of these tests are already in wide use for assessing cognitive functions in children, including a standard intelligence test, several tests of auditory processing, and a number of standard neuropsychological tests. (cdc.gov)
  • Specific tests such as Auditory Evoked Response Potential (AERP) testing and SPECT brain scans have shown significant changes in people suffering Multiple chemical sensitivities, and these changes are consistent with neurotoxic brain damage. (ozemail.com.au)
  • If the patient fixates long after the response reaches its peak, the nystagmus intensity may not be sufficient to produce a valid test of fixation. (audiologyonline.com)
  • However, mPFC inhibition, which eliminates task engagement-induced auditory ERP suppression, did not prevent mice from making decisions based on auditory cues. (jneurosci.org)
  • This will ensure that the nystagmus intensity just before fixation is still strong enough to produce a valid test of fixation suppression while at the same time, preserving the peak of caloric responses. (audiologyonline.com)
  • The common protocol requires testing fixation suppression for at least one right-beating and one left-beating caloric response. (audiologyonline.com)
  • We hope to develop methods that can tell if people are awake in operations using either the brain response to sound, or the patterns of connection in the brain. (southampton.ac.uk)
  • During caloric irrigations, shortly after the peak of the response, the patient is instructed to fixate on a small stationary target. (audiologyonline.com)
  • Here, we instructed human volunteers to classify words with lateralized hand responses while falling asleep. (jneurosci.org)
  • Particular interests include: cooperative behaviour, echolocation, the efficient estimation of auditory evoked potentials for assessment of hearing and of depth of anaesthesia, cerebral hydrodynamic modelling and non-invasive assessment of intracranial complicance, and processing of fluoroscopic images for measurement of spine kinematics. (southampton.ac.uk)
  • OAE measures the preneural status of the peripheral auditory system to the outer hair cells of the inner ear (cochlea). (unicare.com)
  • This is known as a stimulus artifact, and researchers and clinicians seek to avoid it, as it is a contamination of the true recorded response of the nervous system. (wikipedia.org)
  • Advances in imaging techniques, such as MRI, greatly improved the diagnosis and localization of cerebral infarcts that coincide with primary or secondary auditory centers. (wikipedia.org)
  • The ascending auditory pathways are damaged, causing a loss of perception of sound. (wikipedia.org)
  • He exhibited a response towards the occasional sudden, loud sound, however, by turning his head. (wikipedia.org)