Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.
Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.
Parasympathetic Nervous System
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Autonomic Nervous System
The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.
Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.
An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage.
Dose-Response Relationship, Drug
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Optic Nerve Injuries
Injuries to the optic nerve induced by a trauma to the face or head. These may occur with closed or penetrating injuries. Relatively minor compression of the superior aspect of orbit may also result in trauma to the optic nerve. Clinical manifestations may include visual loss, PAPILLEDEMA, and an afferent pupillary defect.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Neoplasms, Ductal, Lobular, and Medullary
The decrease in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Vasoactive Intestinal Peptide
An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.
The amount of a substance secreted by cells or by a specific organ or organism over a given period of time; usually applies to those substances which are formed by glandular tissues and are released by them into biological fluids, e.g., secretory rate of corticosteroids by the adrenal cortex, secretory rate of gastric acid by the gastric mucosa.
Receptor, Muscarinic M2
Receptor, Muscarinic M1
A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING.
Sympathetic Nervous System
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
The major nerves supplying sympathetic innervation to the abdomen. The greater, lesser, and lowest (or smallest) splanchnic nerves are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses. The lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia.
Metrifonate increases neuronal excitability in CA1 pyramidal neurons from both young and aging rabbit hippocampus. (1/2794)The effects of metrifonate, a second generation cholinesterase inhibitor, were examined on CA1 pyramidal neurons from hippocampal slices of young and aging rabbits using current-clamp, intracellular recording techniques. Bath perfusion of metrifonate (10-200 microM) dose-dependently decreased both postburst afterhyperpolarization (AHP) and spike frequency adaptation (accommodation) in neurons from young and aging rabbits (AHP: p < 0.002, young; p < 0.050, aging; accommodation: p < 0.024, young; p < 0.001, aging). These reductions were mediated by muscarinic cholinergic transmission, because they were blocked by addition of atropine (1 microM) to the perfusate. The effects of chronic metrifonate treatment (12 mg/kg for 3 weeks) on CA1 neurons of aging rabbits were also examined ex vivo. Neurons from aging rabbits chronically treated with metrifonate had significantly reduced spike frequency accommodation, compared with vehicle-treated rabbits. Chronic metrifonate treatment did not result in a desensitization to metrifonate ex vivo, because bath perfusion of metrifonate (50 microM) significantly decreased the AHP and accommodation in neurons from both chronically metrifonate- and vehicle-treated aging rabbits. We propose that the facilitating effect of chronic metrifonate treatment on acquisition of hippocampus-dependent tasks such as trace eyeblink conditioning by aging subjects may be caused by this increased excitability of CA1 pyramidal neurons. (+info)
Indirect evidence for cholinergic inhibition of intestinal bicarbonate absorption in humans. (2/2794)BACKGROUND: The aim of the study was to test the hypothesis that in the fasting state, proximal intestinal HCO3- absorption, which depends on villus Na+/H+ exchanger activity, is tonically inhibited by a cholinergic atropine sensitive mechanism. SUBJECTS: The experiments were performed in 34 healthy volunteers and in eight patients with intestinal villus atrophy. METHODS: HCO3- absorption was measured with a modified triple lumen perfusion technique in the distal duodenum, the most proximal portion of the small intestine. The study was designed to compensate for the inhibitory effects of atropine on intestinal motor activity. RESULTS: Atropine had three effects on HCO3- transport: it reduced HCO3- concentration at the proximal aspiration site, it displaced the relation between HCO3- concentration and HCO3- absorption to the left, and it induced a significant acidification of the perfusate at the distal aspiration site. The magnitude of the stimulatory effect on HCO3- absorption was similar to the difference between patients with intestinal villus atrophy and healthy controls. CONCLUSION: The data suggest that, in the fasting state, duodenal HCO3- absorption, which depends on villus Na+/H+ exchanger activity, may be tonically inhibited by an atropine sensitive cholinergic mechanism. (+info)
Intestinal prokinesia by two esters of 4-amino-5-chloro-2- methoxybenzoic acid: involvement of 5-hydroxytryptamine-4 receptors and dissociation from cardiac effects in vivo. (3/2794)In five fasting, conscious dogs, we compared the prokinetic action of two selective 5-hydroxytryptamine-4 (5-HT4) receptor agonists with low affinity for 5-HT3 receptors ML10302 (2-piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate) and SR59768 (2-[(3S)-3-hydroxypiperidino]ethyl 4-amino-5-chloro-2-methoxybenzoate) in the duodenum and jejunum, using cisapride as a reference compound. Heart rate and rate-corrected QT (QTc) also were monitored to assess whether or not the cardiac effects of cisapride are shared by other 5-HT4 receptor agonists. Both ML10302 and SR59768 dose-dependently stimulated spike activity in the duodenum with similar potencies (dose range, 3-300 nmol/kg i.v.; ED50 values: 24 and 23 nmol/kg i.v., respectively), mimicking the effect of cisapride (30-3000 nmol/kg i.v.). The maximal effect was achieved with the dose of 100 nmol/kg i.v. for both compounds. Similar findings were obtained in the jejunum. Atropine and GR125487 (1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate, selective 5-HT4 receptor antagonist), at doses having no effect per se, antagonized intestinal prokinesia by maximal doses of ML10302 and SR59768. Neither ML10302 nor SR59768 had any effect on heart rate or QTc at any of the doses tested, whereas cisapride, at the highest dose (3000 nmol/kg), induced tachycardia and lengthened the QTC (p <.01). In conclusion, ML10302 and SR59768 share with cisapride a similar prokinetic action in the canine duodenum and jejunum in vivo. This effect is mediated by pathways involving activation of 5-HT4 and muscarinic receptors. Unlike cisapride, which induces tachycardia and prolongs the QTc by a mechanism probably unrelated to 5-HT4 receptor activation, ML10302 and SR59768 are devoid of cardiac effects in this model. (+info)
Neuroregulation by vasoactive intestinal peptide (VIP) of mucus secretion in ferret trachea: activation of BK(Ca) channels and inhibition of neurotransmitter release. (4/2794)1. The aims of this study were to determine: (1) whether vasoactive intestinal peptide (VIP) regulates cholinergic and 'sensory-efferent' (tachykininergic) 35SO4 labelled mucus output in ferret trachea in vitro, using a VIP antibody, (2) the class of potassium (K+) channel involved in VIP-regulation of cholinergic neural secretion using glibenclamide (an ATP-sensitive K+ (K(ATP)) channel inhibitor), iberiotoxin (a large conductance calcium activated K+ (BK(ca)) channel blocker), and apamin (a small conductance K(ca) (SK(ca)) channel blocker), and (3) the effect of VIP on cholinergic neurotransmission using [3H]-choline overflow as a marker for acetylcholine (ACh) release. 2. Exogenous VIP (1 and 10 microM) alone increased 35SO4 output by up to 53% above baseline, but suppressed (by up to 80% at 1 microM) cholinergic and tachykininergic neural secretion without altering secretion induced by ACh or substance P (1 microM each). Endogenous VIP accounted for the minor increase in non-adrenergic, non-cholinergic (NANC), non-tachykininergic neural secretion, which was compatible with the secretory response of exogenous VIP. 3. Iberiotoxin (3 microM), but not apamin (1 microM) or glibenclamide (0.1 microM), reversed the inhibition by VIP (10 nM) of cholinergic neural secretion. 4. Both endogenous VIP (by use of the VIP antibody; 1:500 dilution) and exogenous VIP (0.1 microM), the latter by 34%, inhibited ACh release from cholinergic nerve terminals and this suppression was completely reversed by iberiotoxin (0.1 microM). 5. We conclude that, in ferret trachea in vitro, endogenous VIP has dual activity whereby its small direct stimulatory action on mucus secretion is secondary to its marked regulation of cholinergic and tachykininergic neurogenic mucus secretion. Regulation is via inhibition of neurotransmitter release, consequent upon opening of BK(Ca) channels. In the context of neurogenic mucus secretion, we propose that VIP joins NO as a neurotransmitter of i-NANC nerves in ferret trachea. (+info)
Anaphylactic bronchoconstriction in BP2 mice: interactions between serotonin and acetylcholine. (5/2794)1. Immunized BP2 mice developed an acute bronchoconstriction in vivo and airway muscle contraction in vitro in response to ovalbumin (OA) and these contractions were dose dependent. 2. Methysergide or atropine inhibited OA-induced bronchoconstriction in vivo and airway muscle contraction in vitro. 3. Neostigmine potentiated the OA-induced bronchoconstriction in vivo and airway muscle contraction in vitro of BP2 mice. This potentiation was markedly reduced by the administration of methysergide or atropine and when the two antagonists were administered together, the responses were completely inhibited. 4. Neostigmine also potentiated the serotonin (5-HT)- and acetylcholine (ACh)-induced bronchoconstriction and this potentiation was significantly reversed by atropine. 5. These results indicate that OA provokes a bronchoconstriction in immunized BP2 mice by stimulating the release of 5-HT, which in turn acts via the cholinergic mediator, ACh. (+info)
Mixed agonist-antagonist properties of clozapine at different human cloned muscarinic receptor subtypes expressed in Chinese hamster ovary cells. (6/2794)We recently reported that clozapine behaves as a partial agonist at the cloned human m4 muscarinic receptor subtype. In the present study, we investigated whether the drug could elicit similar effects at the cloned human m1, m2, and m3 muscarinic receptor subtypes expressed in the Chinese hamster ovary (CHO) cells. Clozapine elicited a concentration-dependent stimulation of [3H]inositol phosphates accumulation in CHO cells expressing either the m1 or the m3 receptor subtype. Moreover, clozapine inhibited forskolin-stimulated cyclic AMP accumulation and enhanced [35S] GTP gamma S binding to membrane G proteins in CHO cells expressing the m2 receptor. These agonist effects of clozapine were antagonized by atropine. The intrinsic activity of clozapine was lower than that of the full cholinergic agonist carbachol, and, when the compounds were combined, clozapine potently reduced the receptor responses to carbachol. These data indicate that clozapine behaves as a partial agonist at different muscarinic receptor subtypes and may provide new hints for understanding the receptor mechanisms underlying the antipsychotic efficacy of the drug. (+info)
Wavelet transform to quantify heart rate variability and to assess its instantaneous changes. (7/2794)Heart rate variability is a recognized parameter for assessing autonomous nervous system activity. Fourier transform, the most commonly used method to analyze variability, does not offer an easy assessment of its dynamics because of limitations inherent in its stationary hypothesis. Conversely, wavelet transform allows analysis of nonstationary signals. We compared the respective yields of Fourier and wavelet transforms in analyzing heart rate variability during dynamic changes in autonomous nervous system balance induced by atropine and propranolol. Fourier and wavelet transforms were applied to sequences of heart rate intervals in six subjects receiving increasing doses of atropine and propranolol. At the lowest doses of atropine administered, heart rate variability increased, followed by a progressive decrease with higher doses. With the first dose of propranolol, there was a significant increase in heart rate variability, which progressively disappeared after the last dose. Wavelet transform gave significantly better quantitative analysis of heart rate variability than did Fourier transform during autonomous nervous system adaptations induced by both agents and provided novel temporally localized information. (+info)
Assessment of cardiac sympathetic regulation by respiratory-related arterial pressure variability in the rat. (8/2794)1. Mechanical ventilation evokes a corresponding arterial pressure variability (APV) which is decreased by beta-adrenoceptor antagonism. Therefore, in this study we set out to determine whether the respiratory-related APV can be used to assess cardiac sympathetic tone. 2. Computer-generated broad-band mechanical ventilation (0-3 Hz) was applied to Sprague-Dawley rats that had been anaesthetized with ketamine and paralysed with pancuronium. APV and its relationship to lung volume variability (LVV-APV) was systematically quantified with auto- or cross-spectral frequency domain analysis. 3. APV and LVV-APV transfer magnitudes between 0.5 and 1.5 Hz showed dose-dependent suppression by propranolol from 0.01 to 1 mg kg-1, while the static value of arterial pressure remained unchanged. Stroke volume variability, assessed by the use of a pulse contour method, exhibited a similar pattern of suppression by propranolol. In contrast, heart rate variability was not lowered with propranolol. 4. The effect of propranolol on respiratory-related APV persisted even in the presence of combined alpha-adrenoceptor and muscarinic receptor blockade by phentolamine and atropine. 5. The frequency range of 0.5-1.0 Hz was optimal for LVV-APV transfer magnitude to correlate with cardiac sympathetic tone. 6. We conclude that respiratory-related APV may provide a valid assessment of cardiac sympathetic regulation which is independent of parasympathetic and vascular sympathetic influences in ketamine-anaesthetized and positive pressure-ventilated rats. (+info)
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Cumulative addition of atropine to the organ bath containing endothelium-intact (+E) rat aorta, which was precontracted with phenylephrine (PE, 1 microM) and subsequently relaxed with carbachol (1 microM), caused biphasic changes in the vascular contractility of +E rat aortic rings. Low concentrations of atropine (10 nM-1.0 microM) caused progressive restoration of contraction to PE; whereas at higher concentrations (1-100 microM), atropine caused progressive relaxation. Atropine-induced aortic relaxation was significantly inhibited upon endothelium removal by either rubbing or saponin treatment, but considerable relaxation still persisted in the range of 30-100 microM atropine. Similar findings were also obtained when the nitric oxide (NO) generation was inhibited with 300 microM NO synthase inhibitor, L-NAME. Atropine-induced relaxation was also observed when 5-hydroxytryptamine (5-HT) was used as the agonist and the atropine-relaxation was more potent at lower concentrations of PE and 5-HT. ...
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All 5 glass analyze tubes using 1200 I?l of unadulterated water on each was taken. For the test conduit 1, 3 I?l associated with 10 ten I?M atropine was put in and was mixed perfectly. 300 I?l of the method was included to tube some and mixed well. The exact same method is performed for a number of dilutions being done in pipe 3 to 5. Atropine concentration in each tv is considered. Seven triplicate tubes (A1, A2, A3aˆ¦G1, G2, G3) are made each containing 1500 I?l of just one. 3nM QNB assay plus the tubes tend to be mixed properly. 300 I?l of 10 I?M atropine was added to the three pipes of A along with three H tubes had been added along with 300 I?l of choice from pipe 1 . The main dilution technique was executed for hoses C, Def, E, Y from water line 2, tube 3, tubing 4 in addition to tube some respectively. In order to tubes F, 300 I?l of purified water appeared to be added alternatively. 200 I?l membrane seemed to be then additional quickly to any or all the pontoons. The 18 tubes happen to ...
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Atropine is a muscarinic receptor antagonist. Atropine is used in eye examination. Atropine may lead to pupil dilation and paralysis of the eye accommodation. Atropine will form the treatment for cardiac slowing and antidote for poisoning due to anti chol
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Atropine causes the muscles in your eye to become relaxed. This widens (dilates) your pupil so that it will not respond to light. Atropine ophthalmic (for the eye) is used to dilate your pupils when you have an inflammatory condition or in postsurgery situations in which this effect may be helpful. Atropine ophthalmic...
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US EPA PC Code ); 3059 (CA DPR Chem Code) ); 51-55-8 (CAS number); 51558 (CAS number without hyphens); 900358 (US EPA PC Code Text ); Atropine; ATROPINE (CA DPR Chem Code Text ); endo(+-)-alpha-(Hydroxymethyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester benzeneacetic ...
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Understand the usages of Atropine in various health conditions. Explore other smart treatment options, see research evidence, and find out about peoples experiences with many popular treatments, including feedback from patients and professionals.
ChemIDplus - 6415-90-3 - VZDNSFSBCMCXSK-RIMUKSHESA-N - Atropine hydrobromide - Similar structures search, synonyms, formulas,...
6415-90-3 - VZDNSFSBCMCXSK-RIMUKSHESA-N - Atropine hydrobromide - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Abstract properties in PHP | Canned Atropine!!
in iDevelop, PHP , 3 comments. What are abstract properties? There are abstract methods but the notion of an abstract property seems a bit ridiculous. Why so, you might ask! Well, the thing is, methods are declared & defined (not necessarily at same time). So you can declare a method without actually defining it (ie., no body, no set of commands which it will execute) and the same can be defined at a later stage. But there is no such thing as defining a property of a class; properties are always declared as containers of data which reserve a space in memory on class initialization.. As I was re-factoring data validation service in a project Im working on (will open source it once first working draft is ready), I thought about making the ...
ATROPINE 1mg 1ml 1ml 100TK ⋆ MediKeep
Mõned ravimid põhjustavad tugevaid kõrvaltoimeid või ei ole nende toime ootuspärane, kuna mõjuvad kas liiga tugevalt või on nende toime liiga nõrk - põhjus on inimese omapäras ja geneetikas. Ravimite omastamist mõjutab veel mikrobioom. Teadust, mis uurib ravimi toimeainete sobivust nimetatakse farmakogenoomikaks ja sellel on väga oluline roll personaalmeditsiinis. Geenitest võib näidata kätte sobiva toimeaine või anda vastust, miks mõni ravim ei ole sobinud.. Päring aitab selgitada, kas teadusuuringud on leidnud seose ravimi sobivuse ja geneetika vahel ...
Pro.medicin.dk er en hjemmeside og database, der indeholder information om lægemidler og behandlingsvejledninger til læger, farmaceuter og andre sundhedsprofessionelle. Al information er skrevet på fagsprog. Vil du gerne læse information om medicin og behandling, der ikke er på fagsprog, så besøg min.medicin.dk. ...
Visi Vaistai - Atropine Alcon 1% Collyre lašai 10ml
Informacija apie visus Lietuvos vaistinėse pardavinėjamus vaistus, maisto papildus, medicinines prekes bei visas Lietuvos vaistinių tinklų akcijas.
Atropine - Tags - Forums - De Hollandse Psychonaut
Afficher le sujet - BIGOÛT RECORDS distro
cest les soldes dans la Atropine sur plein de disques vieux, introuvables, invendables. TOUT DOIT PARTIR ! ça pèse lourd à transporter et ça sert à rien quand des disques trainent dans un bac plutôt que chez des gens qui les écoutent ...
A few more moderators - Page 7 - WolfQuest
Also to you Atropine, who I partially know, but I do know you are all very helpful and knowledgeable enough to get the jobs and do them awesomely! ...
NDC 0054-3194 Diphenoxylate Hydrochloride And Atropine Sulfate Diphenoxylate Hydrochloride And Atropine Sulfate
Diphenoxylate Hydrochloride And Atropine Sulfate with NDC 0054-3194 is a a human prescription drug product labeled by West-ward Pharmaceuticals Corp.. The generic name of Diphenoxylate Hydrochloride And Atropine Sulfate is diphenoxylate hydrochloride and atropine sulfate.
Adjunctive Atropine During Ketamine Sedation - Full Text View - ClinicalTrials.gov
The degree of secretion was significantly less in the atropine group compared with the control group at the end of the procedure (VAS score: 16.5 ± 9.9 vs. 27.0 ± 15.9, atropine vs. control, p = 0.00). The change in the degree of secretion between the start and end of the procedure was significantly greater in the atropine group than in the control group (p = 0.00) (Fig. 2). However, the frequency of hypersalivation as predefined (VAS score ≥50) did not differ between the groups (p = 0.06).. The only complication that differed significantly between the two groups was tachycardia (p , 0.05). Complications such as aspiration, laryngospasm, and apnea were not documented in the hospital. There were fewer interventions for hypersalivation in the atropine group, but the difference was not significant (p , 0.05). As interventions, O2 administration and endotracheal intubation were not needed. After discharge, the control patients tended to have more complaints of nausea, vomiting, and ataxia, ...
DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE: Pharmaceutical manufacturers, suppliers, and distributors
Generic DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE availability. Has a generic version of DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE been approved? Find suppliers, manufacturers, and packagers
Effect of Atropine on Vascular Adrenergic Neuroeffector Transmission - ScienceOpen
Atropine, homatropine, scopolamine, procaine, lidocaine and phentolamine inhibited the contractile response of rabbit isolated pulmonary artery elicited by electrical-field stimulation. Methylatropine had no effect. The inhibition induced by atropine (2 × 10|sup|-6|/sup|-2 × 10|sup|-4|/sup| m) had a rapid onset of action and then remained almost constant. The inhibition was slowly reversible. The potency of atropine as an inhibitor of responses to field stimulation was very much less than the potency of phentolamine. The inhibition was not antagonized by cocaine or (+)-amphetamine. Atropine (3 × 10|sup|-5|/sup| and 3 × 10|sup|-4|/sup| m) enhanced the electrical-field-stimulation-induced outflow of tritium from the pulmonary artery preloaded with |sup|3|/sup|H-(-)-noradrenaline. In contrast, atropine in a concentration-dependent manner either had no effect or slightly decreased the tyramine-induced outflow of tritium. Atropine reduced the contractile response of the pulmonary artery evoked by
Vasoactive intestinal polypeptide and muscarinic receptors: supersensitivity induced by long-term atropine treatment
Long-term treatment of rats with atropine induced large increases in the numbers of muscarinic receptors and receptors for vasoactive intestinal polypeptide in the salivary glands. Since receptors for vasoactive intestinal polypeptide coexist with muscarinic receptors on the same neurons in this preparation, the results suggest that a drug that alters the sensitivity of one receptor may also affect the sensitivity of the receptor for a costored transmitter and in this way contribute to the therapeutic or side effects of the drugs ...
Topical Atropine for Myopia Management: The Latest Research - Review of Myopia Management
Visiting Research Scientist, Brien Holden Vision Institute. A network meta-analysis on myopia control found that use of atropine at different concentrations was significantly superior to other interventions (for example, progressive addition spectacle lenses, multifocal soft contact lenses, orthokeratology, more outdoor activities, etc.)1 Other reviews and meta-analysis similarly concluded that there was less myopic progression with atropine and that both the efficacy and adverse effects were dose-dependent.2, 3. Atropine is a non-selective muscarinic acetylcholine receptor antagonist (mAchR), and the underlying mechanisms by which it controls myopia progression remain unclear. Initially, it was thought that the drug acted via accommodative mechanisms. Later evidence suggested that the mechanism was via non-accommodative pathways,4 with some reports suggesting that atropine exerted its action via retinal amacrine cells and dopamine; when atropine binds to mAchR on the cells, they could release ...
A patch or eye drops are similarly effective for the treatment of lazy eye in children - NIHR Evidence
This review delivers important findings: atropine blurring is as effective as patching in improving vision in the amblyopic eye and has a lasting effect. This means that practitioners can confidently offer parents the choice of either modality as first-line treatment after glasses. Importantly, the review also highlights the risk of reducing vision in the better-seeing eye, reminding practitioners that close monitoring is required for children receiving atropine treatment. Lastly, it is a welcome finding that atropine treatment improves childrens quality of life.. For researchers, the review is a reminder to either use outcomes which enable meta-analysis across trials or to share primary data.. Annegret Dahlmann-Noor, Honorary Clinical Associate Professor; Consultant in Paediatric Ophthalmology and Strabismus; Clinical Trials Lead in Paediatric Ophthalmology, NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology.. The commentator declares no conflicting ...
Atropine Sulfate Ophthalmic Solution | On Sale | EntirelyPets Rx
Atropine Sulfate Ophthalmic Solution (Manufacturer may vary) and other products can be found at EntirelyPets Rx, the #1 source for fulfilling all of your pet needs. Free Shipping over $59!
Muscarinic blockade of methacholine induced airway and parenchymal lung responses in anaesthetised rats | Thorax
The results of these experiments in anaesthetised Brown Norway rats show that prolonged inhalation of methacholine results in a predominantly parenchymal (or tissue) constrictor response which is effectively reversed by a maximum dose of atropine sulphate but not by pirenzepine. In contrast, intravenous methacholine produced more marked changes in airway resistance which were reversed by pirenzepine.. Our adaptation of the low frequency forced oscillation technique allows lung mechanics to be partitioned into airway and parenchymal components by fitting the constant phase model to the impedance spectra. The airways through which gas moves by bulk flow will be included in the airway component, whereas airways through which gas moves by diffusion are likely to be included in the parenchymal component. It is therefore most likely that the parenchymal response is the result of contraction of smooth muscle in respiratory bronchioles and alveolar ducts and of contractile elements in the alveolar ...
Three gaseous neurotransmitters, nitric oxide, carbon monoxide, and hy by Oladayo Fosaire, Kylie A. Mills et al.
Background/Aims: The internal anal sphincter (IAS) plays an important role in maintaining continence and a number of neurotransmitters are known to regulate IAS tone. The aim of this study was to determine the relative importance of the neurotransmitters involved in the relaxant and contractile responses of the porcine IAS. Methods: Responses of isolated strips of IAS to electrical field stimulation (EFS) were obtained in the absence and presence of inhibitors of neurotransmitter systems. Results: Contractile responses of the sphincter to EFS were unaffected by the muscarinic receptor antagonist atropine (1 µM), but were almost completely abolished by the adrenergic neuron blocker guanethidine (10 µM). Contractile responses were also reduced (by 45% at 5 Hz, P ? 0.01) following desensitisation of purinergic receptors with a,ß,methylene-ATP (10µM). In the presence of guanethidine, atropine and a,ß,methylene-ATP, the remaining relaxatory responses to EFS were examined. These responses were not
neuroscience - Differences in the action of Scopolamine and Atropine - Biology Stack Exchange
Both Scopolamine and Atropine are muscarinic antagonists, having essentially the same action: blocking parasympathetic nerve receptors.. The action on the brain by muscarinic antagonists is presumed to be caused by dilation of blood vessels, thus we might expect the effect on the brain by the two compounds to be similar.. However, in actuality the action of the two compounds on the brain is somewhat different. Scopolamine begins causing strong psychotropic effects even in very small doses before it has any effects on the skeletal nervous system. Conversely, atropine begins having effects on the muscular system long before it begins having psychotropic effects and in fact, potentially toxic doses of atropine have to be administered before significant psychotropic effects begin manifesting.. If the apparent biochemical action of the two compounds is similar, why do we see this difference in the effects between the two with regards to the brain?. ...
More Data Supports Low-dose Atropine for Myopia
The use of atropine to curb myopia remains under investigation, particular the right dosing for the best balance between treatment efficacy and side effects. Adding to the latest research, a new study in JAMA Ophthalmology reports 0.01% atropine eye drops can slow myopia progression and axial elongation in Chinese children. Still, the researchers noted their studys limitations since only about 70% of enrolled subjects returned for follow-up. The randomized, placebo-controlled, double-masked study enrolled 220 children between the ages of six and 12 who had myopia of -1.00D to -6.00D in both eyes. The investigation was conducted at Beijing Tongren Hospital in China, and the childrens cycloplegic refraction and axial length were measured at baseline and at six and 12 months. Patients were randomly assigned in a 1:1 ratio to 0.01% atropine or placebo, administered once nightly to both eyes for one year. The mean baseline refractive error and axial length were -2.58D and 24.59mm.. Follow up at one ...
Donnazyme (Atropine Sulfate; Bile Salts; Hyoscyamine Sulfate...) Wyeth
Donnazyme information about active ingredients, pharmaceutical forms and doses by Wyeth, Donnazyme indications, usages and related health products lists
Atropine Sulfate Effects on Aviator Performance and on Respiratory-Heart Period Interactions | RTI
Effect of Soidum Cromoglycate (SCG) and Atropine on Cough and Wheeze Produced by Inhaling Nebulised Distilled Water | Clinical...
Thank you for your interest in spreading the word about Clinical Science.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
Complex Atropine Cases In Childhood Myopia Control | Myopia Profile
Read these three clinical complex atropine cases where general health conditions required careful consideration of atropine prescribing.
Biochemical and Physiological Studies of the Purified Toxin of Walterinnesia Aegyptea The Egyptian Black Snake | Journal of...
1. Two methods for preparation of the toxin in a purified crystalline form are described.. 2. The toxin is probably a secondary proteose.. 3. It has an excitatory parasympathetic effect on the uterus of the guinea-pig and on the intestine of the rabbit. The effect is abolished by atropine.. 4. It causes excessive salivary secretion, again abolished by atropine.. 5. It causes partial or complete block of perfused isolated amphibian and mammalian hearts. It also causes extrasystoles. Both effects are abolished by atropine.. 6. The minimum lethal dose for rats is 0.035-0.05 mg. toxin/100 g. body weight. Atropine did not save the life of the animal although it prolonged it.. 7. The possibility of a histamine-like action of the venom is discussed.. ...
DuoDote (atropine and pralidoxime) - Drugs and Medication - 635
Find medical information for DuoDote (atropine and pralidoxime) (635), including its uses, information and definitions, as well as for other most po
Edrophonium and Atropine Overview | FoundHealth
Understand Edrophonium and Atropine, usages in various health conditions, and side effects and warnings. Explore other smart treatment options, see research evidence, and find out about peoples experiences with many popular treatments, including feedback from patients and professionals.
IV clonidine does not interfere with the haemodynamic response to atropine in anaesthetized patients | DIAL.pr - BOREAL
Coster, M. ; De Kock, Marc ; Scholtes, Jean-Louis. IV clonidine does not interfere with the haemodynamic response to atropine in anaesthetized patients.In: British Journal of Anaesthesia, Vol. 76, p. A99-A99 (1996 ...
Augmentation of norepinephrines inotropic action by atropine<...
TY - JOUR. T1 - Augmentation of norepinephrines inotropic action by atropine. AU - Ochs, H. R.. AU - Rutherford, J. D.. AU - Vatner, S. F.. PY - 1977/1/1. Y1 - 1977/1/1. UR - http://www.scopus.com/inward/record.url?scp=0017411788&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0017411788&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0017411788. VL - 20. JO - The Physiologist. JF - The Physiologist. SN - 0031-9376. IS - 4. ER - ...
MOTOFEN (Atropine,Difenoxin) dosage, indication, interactions, side effects | EMPR - ONA
MOTOFEN (Atropine,Difenoxin) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
ATROPINE AND SALTS manufacturing companies
Listing your company for ATROPINE AND SALTS allows buyers to find your information through our directory pages which appear in the top positions when a search is conducted in Google, Yahoo!, MSN etc ...
ATROPINE AND SALTS manufacturing companies
Listing your company for ATROPINE AND SALTS allows buyers to find your information through our directory pages which appear in the top positions when a search is conducted in Google, Yahoo!, MSN etc ...
Atropine in Bengali এর ব্যবহার, ডোজ, পার্শ্বপ্রতিক্রিয়া, উপকার, বিক্রিয়া এবং সতর্কতা
Atropine in Bengali - এর ব্যবহার, ডোজ, পার্শ্বপ্রতিক্রিয়া, উপকার, বিক্রিয়া এবং সতর্কতা বিষয়ে তত্ত্বতালাশ করুন
News | AMRI
A 49-year old male is transported to your Emergency Department complaining of tightness in his chest. He is slightly pale. His skin is warm and dry. He is alert and responsive. His blood pressure is 130/88, and his pulse is 46, strong and regular. He has IV access, and is attached to the ECG monitor which shows sinus rhythm with ST segment elevation in lead II. A stat 12-lead ECG shows 4-6mm ST segmental elevation in leads II, III and aVF. The onset of the patients symptoms is less than 30 minutes ago. A member of the team suggests that it would be proper to administer 0.5mg of atropine sulfate I.V. to treat the bradycardia. Full Article. ...
Overheard at Western - Overheard Everywhere
Chick: I just want to rub some ointment containing scopolamine and atropine on a broomstick, stick it in my cooch, and fly away!. http://overheardatwestern.blogspot.com/2007/04/pssh-everyone-feels-this-way-sometimes.html. Overheard by: tiffany. ...
Atropine-onderzoek bij kinderen - Maashorst Oogkliniek
Atropine-onderzoek bij kinderen. Binnenkort komt uw kind naar Bernhoven voor een oogheelkundig onderzoek. In medische termen wordt dit onderzoek atropine-onderzoek genoemd. Ter voorbereiding van het onderzoek worden de ogen gedruppeld met atropine. Atropine schakelt tijdelijk het vermogen van het oog om scherper te stellen (het z.g. accomoderen) uit. Het oog komt hierdoor in een rusttoestand, zodat bekeken kan worden of uw kind nu of in de toekomst een bril nodig heeft. In deze folder leest u welke voorbereiding u voor het atropine-onderzoek moet treffen.. Wat moet u doen als u niet kunt komen?. Belt u ons op tijd wanneer u uw afspraak voor het onderzoek niet kunt nakomen? Er wordt dan een nieuwe afspraak gemaakt. U kunt bellen naar Maashorst Oogkliniek, 0413 - 40 19 56.. Waar meldt u zich? Op de afgesproken dag en tijd meldt u zich bij Maashorst Oogkliniek, route 020.. Hoe bereidt u uw kind thuis voor? Instructie druppelen Op de polikliniek oogheelkunde heeft u een recept voor atropine druppels ...
1. The stomach and intestine of the dog isolated half an hour after a hypodermic injection of 1 mg. atropine per kilo only contract weakly and with diminishing strength. The tone falls rapidly. The same is true for the stomach. These effects persist as a general rule for five or six hours or longer, at any rate in the intestine.. 2. The same depressant action may be obtained after 0.1 mg. or 0.005 mg., while after 0.001 mg. the movement is normal though the tone falls rapidly.. 3. The production of the substance which excites movement and the reaction of the intestine to this substance did not seem to be influenced by the previous injection of atropine.. 4. The extract of the stomach or of the intestine has no influence on the contraction or tonus of the isolated stomach.. ...
Dr. Brien Holden, Myopia,and Atropine - Mindsight
Dr. Brien Holden was an optometric giant. He was a renowned researcher, educator and humanitarian. Dr. Holden worked tirelessly toward advancing eye care and reducing visual impairment worldwide. A few months before he died, he brought together scientists, researchers and clinicians from around the world to address the rapidly increasing prevalence of myopia and the…
MRCOphth Part I MCQs 168
a. is inhibited by atropine b. is increased by vagal stimulation c. is inhibited by amino acids d. is stimulated by beta agonists e. is greater with intravenous glucose than oral glucose ...
Tropan - Wikipedija, prosta enciklopedija
Tropan je biciklična organska spojina, ki vsebuje dušik. Po njem se imenuje skupina tako imenovanih tropanskih alkaloidov. Mednje sodita med drugimi atropin in kokain, ki v svoji strukturi vsebujeta tropinon, katerega derivat je tudi tropan. Tropanski alkaloidi se nahajajo v rastlinah iz družin kokovk (vključno s koko) in razhudnikovk (vključno z volčjo češnjo, paradižnikom in krompirjem). 8-azabiciklo[3.2.1]oktan (tropan brez 8-metilne skupine) imenujemo nortropan. Tropan dobimo s kondenzacijo piperidina in pirolidina. ...
IMISAN - BIVECO
Imisan mazkur qollanmaga muvofiq tavsiya etilgan dozalarda qollanganda, hayvonlarda nojoya tasiri va asoratlari kuzatilmaydi. Kam hollarda kiritilgan joyida giperemiya yoki ogriqli shishib ketish shaklidagi mahalliy reaktsiya bolishi mumkin, u 1 -2 sutkadan keyin yoqoladi. Takroriy kiritishda qon bosimi pasayishi, preparatning dozasi oshib ketganda esa bradikardiya, nafas olish tezlashishi va buzilishi, anoreksiya, tremor kuzatilishi mumkin.. Hayvonning preparatga yuqori individual sezgirligida asoratlar rivojlanishi belgilari bolishi mumkin (holsiz holati, notinchik, kop solak oqishi, koz yoshi oqishi, ter ajralishi, mushaklar titrashi, tez-tez siyish va ich ketishi), bu hollarda teri ostiga 1 % atropin eritmasi belgilanadi. Qon parazitlari ommaviy qirilganda va eritrotsitlar parchalanganda hayvonlarda intoksikatsiya rivojlanishi mumkin. Bu holda elektrolitlar eritmalarini tomir ichiga quyish va simptomatik davolashni oz ichiga oluvchi intensiv davolash otkazilishi lozim.. MAN ...
Atropine Ophth Ointment 1% is currently on Manufacturer Back Order. If you have any questions please contact us at [email protected] ...
Nalgene Bottles - Nalgene Round Leakproof Travel Bottles | The Container Store
Enjoy free shipping on all purchases over $75 and free in-store pickup on the Nalgene Round Leakproof Travel Bottles at The Container Store. Taking your own hair care products, lotions, baby oil, or body wash on a trip has never been more worry-free. Our Nalgene Round Leakproof Bottles are made of the same laboratory-quality seal used to package essential oils and toxic chemicals, and they are guaranteed not to leak. So enjoy the protection these bottles provide. Their compact size also makes them perfect for a travel kit, cosmetic bag, purse, backpack or briefcase.
Varghese, S.; Vettath, N.; Iyer, K.; Puliyel, J. M.; Puliyel, M. M. (1990). "Ocular atropine induced psychosis--is there a ... Bergman, K. R.; Pearson, C.; Waltz, G. W.; Evans R. III (1980). "Atropine-induced psychosis. An unusual complication of therapy ... Prednisone and other corticosteroids Isotretinoin Anticholinergic drugs atropine scopolamine antidepressants L-dopa ... with inhaled atropine sulfate". Chest. 78 (6): 891-893. doi:10.1378/chest.78.6.891. PMID 7449475. ...
It is mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include atropine and cocaine, ... "Atropine content of plants". USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases. [Online ...
Atropine is an alkaloid first found in Atropa belladonna, a member of the nightshade family. While atropine was first isolated ... Overdosing of atropine may lead to atropine poisoning which results in side effects such as blurred vision, nausea, lack of ... "Atropine Side Effects Center". "Resveratrol: MedlinePlus Supplements". medlineplus.gov. Retrieved 2020-04-07. Vang O, Ahmad N, ... Currently atropine is administered intraveinously to treat bradycardia and as an antidote to organophosphate poisoning. ...
Active ingredients are listed as: phenobarbital (16.2 mg), hyoscyamine sulfate (0.1037 mg), atropine sulfate (0.0194 mg), and ... compared Donnatal® tablets (hyoscyamine sulfate - 0.1037 mg; atropine sulfate - 0.0194 mg; scopolamine hydrobromide - 0.0065 mg ... and phenobarbital - 16.2 mg) to belladonna alkaloids alone (hyoscyamine sulfate - 0.1037 mg; atropine sulfate - 0.0194 mg; ...
An emergency antidote is atropine. Diazinon was developed in 1952 by the Swiss company Ciba-Geigy (now Novartis) to replace the ... Geller, Robert J.; Lopez, Gaylord P.; Cutler, Stephen; Lin, Diana; Bachman, George F.; Gorman, Susan E. (2003). "Atropine ... including the antidotes atropine and oxime. Gastric Lavage Patients that continue to improve over the first 4 ... availability as an antidote for nerve agent casualties: Validated rapid reformulation of high-concentration atropine from bulk ...
The specific antidote is atropine. Inducing vomiting to remove mushroom contents is also prudent due to the speed of onset of ...
... atropine and pralidoxime chloride kit". DailyMed. 22 March 2017. Retrieved 27 May 2020. "Duodote- atropine and pralidoxime ... The ATNAA provides atropine and pralidoxime chloride in a single delivery system, although the two drugs are separate within ... "Atropine mixture with pralidoxime chloride". Drug Information Portal. U.S. National Library of Medicine. Medicine portal. ... ATNAA Factsheet: http://www.accessdata.fda.gov/drugsatfda_docs/nda/2002/21175_Atnaa_prntlbl.pdf "Atnaa Atropine And Pralidoxime ...
Rapid sequence induction
Atropine is a parasympathetic blocker. The common premedication dose for atropine is 0.01-0.02 mg/kg. With standard intravenous ... Atropine is a muscarinic receptor antagonist, thus blocking the vagal response. The dose is 0.01 mg/kg. It has quick onset of ... Atropine may also be used as a premedication agent in pediatrics to prevent bradycardia caused by hypoxia, laryngoscopy, and ... Atropine - The process of intubation can cause massive stimulation to vagus nerve, causing bradycardia (low heart rate). The ...
Atropine, hyoscyamine, scopolamine, etc.) Anticonvulsants (Topiramate, carbamazepine, lamotrigine, etc.) Antihistamines ( ...
The specific antidote is atropine. List of deadly fungi Carluccio A (2003). The Complete Mushroom Book. Quadrille. ISBN 1-84400 ...
The most common is called Atropine. Indirect-acting antagonist- drugs that inhibit the release/production of neurotransmitters ...
The US Army has funded studies of the use of galantamine along with atropine in the treatment of a number of nerve agents, ... Increasing the dose of galantamine from 5 to 8 mg/kg decreased the dose of atropine needed to protect experimental animals from ... The use of a fast-acting peripheral anticholinergic drug such as atropine can block the receptors where acetylcholine acts to ... In the treatment of nerve agent poisoning, atropine is most often administered along with a Hagedorn oxime such as pralidoxime ...
"Atropine - Myasthenia-gravis medicines and drugs". NHS Choices. 2014. Archived from the original on 12 July 2015. Retrieved 11 ... Another medication used for MG, atropine, can reduce the muscarinic side effects of acetylcholinesterase inhibitors. ...
"Atropine and bradycardia after myocardial infarction". Kounis NG, Chopra RK. Ann Intern Med 1974; 81: 117-8. "Oxytetracycline- ...
Equine recurrent uveitis
The mydriatic of choice is atropine. In the periods between acute attacks, no therapy has been shown to be beneficial. Horses ...
Spinal cord injury
... treatment to speed it may include atropine. The corticosteroid medication methylprednisolone has been studied for use in SCI ...
Department of Pharmacology, University College London
CS1 maint: discouraged parameter (link) Paton, W.D.M.; Rang, H.P. (1965). "The Uptake of Atropine and Related Drugs by ... Clark, A.J. (1926). "The antagonism of acetyl choline by atropine". Journal of Physiology. 61 (4): 547-546. doi:10.1113/ ...
Atropine can be given when children produce a vagal response, evidenced by bradycardia, in response to intubation. Some ... Pretreatment includes 100% oxygen, lidocaine, and atropine. 100% oxygen should be administered for 3 to 5 minutes. The time ...
This pathway will be inhibited by atropine. Gastrin is transferred from a specific type of G cell in the gastric epithelium to ... which is of particular importance because the administration of atropine will not block the vagal stimulation of the G cells, ...
Patients with bradycardia are treated with atropine. Atropine is a muscarinic antagonist, which can obstruct the muscarinic ... Hyperthermia, dilated pupils and dry mouth are side effects associated with the use of atropine. Botulinum toxin A is an ... significance and atropine: Figure 1". Archives of Disease in Childhood. 97 (2): 139-144. doi:10.1136/adc.2010.210518. ISSN 0003 ...
Atropine is administered for slowed heart rate. J.M. Piepmeyer, K.B. Lehmann and J.G. Lane, Cardiovascular instability ...
Slade, T J; Grover, J; Benger, J (2008). "Atropine-resistant bradycardia due to hyperkalaemia" (PDF). Emergency Medicine ...
... (INN) is a atropine derivative. In the US its patent number is 3,356,682. It is sold by Sanofi-Aventis and ...
These symptoms are initially treated with atropine, a muscarinic receptor agonist. In a case study in which atropine was not ... For animals, reported effective treatment of zygacine poisoning consists of injection of 2 mg of atropine sulfate and 8 mg of ... Suggested treatment of poisoning in humans include administering dopamine and atropine to the patient. For animals, treatment ... "Zigadenus poisoning treated with atropine and dopamine." Journal of Medical Toxicology 5, no. 4 (2009): 214. Bhatt-Mehta, ...
Combat operations in 2013 during the Battle of Aleppo
1,500 doses of atropine were used with a further 2,000 sent by aid agencies. Atropine is a recognised antidote to nerve gases. ...
These include atropine, cyclopentolate, homatropine, scopolamine and tropicamide. They are indicated for use in cycloplegic ... is usually due to topical application of muscarinic antagonists such as atropine and cyclopentolate. Belladonna alkaloids are ...
Controlled Substances Act
... when mixed with atropine (to make it poisonous, if taken at euphoria-inducing dosages). Difenoxin with atropine (Motofen) has ... Without atropine, these drugs are in Schedule II. Cannabidiol, only in a cannabis-derived pharmaceutical formulation marketed ... when combined with atropine (such as Motofen) (difenoxin is 2-3 times more potent than diphenoxylate, the active ingredient in ...
M43 BZ cluster bomb
Goodman E (2010). Ketchum J, Kirby R (ed.). Historical Contributions to the Human Toxicology of Atropine. Eximdyne. p. 120. ...
He uses atropine comas and other outdated methods. Nazaraliev is the father of a daughter and a son. Nazaraliev ran for ...
Ernest Francis Bashford
Bashford, E.F. (1900). Investigation into the antagonism between atropine and morphine (Thesis). University of Edinburgh. hdl: ...
Atropine (album) - Wikipedia
Atropine | Encyclopedia.com
atropine* is an alkaloid derived from the solanaceous plants Atropa belladonna (deadly nightshade ), Hyoscyamus niger (black ... Trade names: Isopto Atropine, Minims Atropine Sulphate.. Cite this article Pick a style below, and copy the text for your ... atropine (at-rŏ-peen) n. an antimuscarinic drug extracted from belladonna. Atropine is used as a mydriatic (see cycloplegia, ... Large doses of atropine can cause hallucination.. Long-lasting pupillary dilation results if atropine drops are placed in the ...
... has part (R)-atropine (CHEBI:48882) atropine (CHEBI:16684) has part (S)-atropine (CHEBI:17486) atropine ... atropine (CHEBI:16684) has role plant metabolite (CHEBI:76924) atropine (CHEBI:16684) is a racemate (CHEBI:60911) ... atropine (CHEBI:16684) has role anti-arrhythmia drug (CHEBI:38070) atropine (CHEBI:16684) has role antidote to sarin poisoning ... atropine (CHEBI:16684) has role mydriatic agent (CHEBI:50513) atropine (CHEBI:16684) has role parasympatholytic (CHEBI:50370) ...
Atropine is a type of medicine called an antimuscarinic (or sometimes called an anticholinergic). It works by relaxing the ... Atropine tablets. Atropine is a type of medicine called an antimuscarinic (or sometimes called an anticholinergic). It works by ... By preventing this, atropine helps the muscle in the gut to relax. This reduces involuntary contractions and spasms of the ... Atropine tablets should be swallowed whole with a glass of water. They can be taken either with or without food. ...
Scopolamine and Atropine | Encyclopedia.com
Atropine, a major alkaloid in deadly nightshade, is also found in Jimsonweed (Datura stramonium ). Source for information on ... SCOPOLAMINE AND ATROPINE Scopolamine (d -hyoscine) and attopine (dl -hyosycamine) is a tropane alkaloid found in the leaves and ... Scopolamine and Atropine: Encyclopedia of Drugs, Alcohol, and Addictive Behavior dictionary. ... Scopolamine and Atropine. Updated About encyclopedia.com content Print Article Share Article ...
Atropine Ophthalmic: MedlinePlus Drug Information
Atropine Ophthalmic: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Before using atropine eye drops or eye ointment,. *tell your doctor and pharmacist if you are allergic to atropine, belladonna ... Atropine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: *eye irritation and ... Atropine comes as a solution (liquid) to instill in the eyes and an eye ointment to apply to the eyes. The drops are usually ...
Atropine eye drops
... contain the active ingredient atropine, which is a type of medicine called an antimuscarinic. It is also ... Atropine eye drops. Atropine eye drops contain the active ingredient atropine, which is a type of medicine called an ... Atropine eye drops contain the active ingredient atropine, which is a type of medicine called an antimuscarinic. It is also ... Atropine eye Drops contain atropine sulfate which belongs to groups of medicines called mydriatics (medicines that widen the ...
Atropine/epinephrine | SpringerLink
Atropine Methonitrate - Drugs.com
A list of US medications equivalent to Atropine Methonitrate is available on the Drugs.com website. ... Atropine Methonitrate is a medicine available in a number of countries worldwide. ... Butropina (Atropine Methonitrate and Secbutabarbital). Vincenti, Venezuela. *Virulex Forte (Atropine Methonitrate and ...
hyoscyamine, atropine, scopolamine & phenobarbital Dosage, Side Effects
... atropine sulfate, scopolamine sulfate and phenobarbital (Donnatal, Donnatal Extentabs) are a combination of drugs used in the ... What are the uses for hyoscyamine, atropine, scopolamine, phenobarbital?. *What are the side effects of hyoscyamine, atropine, ... What are the uses for hyoscyamine, atropine, scopolamine, phenobarbital?. *What are the side effects of hyoscyamine, atropine, ... Which drugs or supplements interact with hyoscyamine, atropine, scopolamine, phenobarbital?. *Is hyoscyamine, atropine, ...
ATROPINE AND OPEN ETHER ADMINISTRATION | The BMJ
Atropine Sulphate Astrazeneca - Drugs.com
A list of US medications equivalent to Atropine Sulphate Astrazeneca is available on the Drugs.com website. ... Atropine Sulphate Astrazeneca is a medicine available in a number of countries worldwide. ... Ingredient matches for Atropine Sulphate Astrazeneca. Atropine. Atropine sulfate monohydrate (a derivative of Atropine) is ... Atropine Sulphate Astrazeneca. Atropine Sulphate Astrazeneca may be available in the countries listed below. ...
Atropine, TMS derivative
Atropine ophthalmic: Click for Drug Side Effects & Dosing
Consumer information about the drug atropine ophthalmic used to treat inflammatory conditions of the eye, and is used prior to ... Is atropine sulfate ointment-ophthalmic available as a generic drug?. *Do I need a prescription for atropine sulfate ointment- ... Is atropine sulfate ointment-ophthalmic available as a generic drug?. *Do I need a prescription for atropine sulfate ointment- ... Ophthalmic atropine is used during eye examinations to dilate the pupil. Atropine is also used to weaken the contraction of the ...
IDF findings: Palestinian woman died of Atropine overdose
... Investigation conclusions prove that Jawaher Abu-Rahma had inhaled ... and thought that she needed to receive large amounts of atropine. After the event it was revealed that had she received a ... the IDF determined Wednesday that she died from an overdose of Atropine administered at the hospital. According to the ...
Atropine - Human Emulsion (2020, CD) | Discogs
Bufopto Atropine ophthalmic : Rate your experience with this treatment
Atropine (Ophthalmic) | Memorial Sloan Kettering Cancer Center
DailyMed - Search Results for Atropine
ATROPINE (atropine sulfate) solution/ drops. NDC Code(s): 17478-215-02, 17478-215-05, 17478-215-15 *Packager: Akorn, Inc. ... ATNAA ATROPINE AND PRALIDOXIME CHLORIDE AUTO-INJECTOR (atropine and pralidoxime chloride) kit. NDC Code(s): 11704-777-01 * ... ATROPINE SULFATE (atropine sulfate) injection. NDC Code(s): 76329-3339-1 *Packager: International Medication Systems, Limited ... ATROPINE (atropine sulfate) solution/ drops. NDC Code(s): 13985-606-05 *Packager: MWI ...
DailyMed - ATROPINE SULFATE injection, solution
ATROPINE SULFATE (UNII: 03J5ZE7KA5) (ATROPINE - UNII:7C0697DR9I) ATROPINE SULFATE. 0.4 mg in 1 mL. ... ATROPINE SULFATE (UNII: 03J5ZE7KA5) (ATROPINE - UNII:7C0697DR9I) ATROPINE SULFATE. 1 mg in 1 mL. ... Atropine Sulfate Injection, USP is a sterile, isotonic solution of Atropine Sulfate in Water for Injection q.s. Sodium Chloride ... ATROPINE SULFATE injection, solution. To receive this label RSS feed. Copy the URL below and paste it into your RSS Reader ...
ATROPINE Lyrics - AMARAN | eLyrics.net
Amaran Atropine lyrics & video : Bathroom mirror laughs so hard, Scribbled lipstick shouting truth Years of whatever, a ... Atropine, your heroine. Grasping for air,. In a room full of cyanide. Its only a matter of time,. Before it all comes crashing ... Atropine Lyrics. Bathroom mirror laughs so hard,. Scribbled lipstick shouting truth. Years of whatever, a decaying youth. And ... check amazon for Atropine mp3 download. Record Label(s): 2008 Listenable Records. Official lyrics by ...
atropine and pralidoxime
Atropine also stimulates the heart and reduces the secretions of the nose, mouth, and lungs to improve breathing. Pralidoxime ... Atropine blocks the action of a certain chemical that may reach high levels in the body after a poisoning. ... What is atropine and pralidoxime?. Atropine blocks the action of a certain chemical that may reach high levels in the body ... How is atropine and pralidoxime given?. Atropine and pralidoxime is injected into a muscle in your upper thigh. A healthcare ...
Atropine Pharmacodynamics. Continued
Atropine Injection: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Find patient medical information for atropine injection on WebMD including its uses, side effects and safety, interactions, ... Atropine SULFATE Syringe Common Brand(S): Generic Name(S): atropine View Free Coupon * Uses ... Does Atropine SULFATE Syringe interact with other medications? * Should I avoid certain foods while taking Atropine SULFATE ... Does Atropine SULFATE Syringe interact with other drugs you are taking? Enter your medication into the WebMD interaction ...
Difenoxin and Atropine | Memorial Sloan Kettering Cancer Center
Эту информацию не следует использовать для принятия решения о приеме этого или любого другого препарата. Только лечащий врач обладает необходимыми знаниями и опытом, чтобы принимать решения о том, какие препараты подходят для конкретного пациента. Данная информация не является гарантией того, что препарат безопасен, эффективен или одобрен для лечения каких-либо заболеваний или конкретных пациентов. Здесь приведены лишь краткие сведения общего характера об этом препарате. Здесь НЕ приводится вся имеющаяся информация о возможном ...
Clipart - Famous (and infamous) molecules 36 - L-atropine
Atropine is a medication that can be used to treat certain types of nerve agent and pesticide poisoning or slow heart rate, and ... Atropine molecule from a public domain image on Wikipedia Commons. ... Famous (and infamous) molecules 36 - L-atropine. By. Firkin. Created. 2017-03-14. Description. Atropine molecule from a public ... atropine , chemical , chemistry , drug , medication , molecule , nightshade. Viewed by. 367 People. Loved by. 1 People. ...
DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (tablet) | Healthgrades.com
... produces many effects in the body, including relief from spasms of the gastrointestinal tract (stomach and intestines ... What is atropine?. Atropine produces many effects in the body, including relief from spasms of the gastrointestinal tract ( ... It is not known whether atropine will harm an unborn baby. Do not take atropine without first talking to your doctor if you are ... It is not known whether atropine passes into breast milk. Do not take atropine without first talking to your doctor if you are ...
Effects of atropineMedicationInjectionDosesAnticholinergicDilated pupilsTroe peenHyoscyamine sulfateEffect of atropineAmounts of atropineTreatment with atropineDilate the pupil0.01SecretionsReceive atropinePralidoximeAlkaloidAmblyopiaDoseAcetylcholineDrops2018DosageNeeded With Ketamine SedationPupilMydriaticsOverdoseDavis's Drug GuideAllergic to atropineKnown whether atropineSymptomsParasympatheticTake atropineWeekend atropineInjectable atropineMyopia Progression in ChildrenDeadly nightshadeOphthalmic ointmentSalivationVentricular fibrillationImproving visual acuityInteractProgressionOintmentBradycardiaBelladonna alkaloidsToxicityPlaceboSide effectsAtropaDrugsScopolamineGlaucomaAntidoteMedicinesOccurs
Effects of atropine8
- What are the side effects of atropine sulfate ointment-ophthalmic? (medicinenet.com)
- What are the possible side effects of atropine and pralidoxime? (rexhealth.com)
- Some of the side effects of atropine and pralidoxime may be similar to the symptoms of poisoning. (rexhealth.com)
- The effects of atropine can last up to two weeks. (bionity.com)
- Read the side effects of Atropine Sulfate Ophthalmic as described in the medical literature. (medindia.net)
- Most of the side effects of atropine are directly related to its antimuscarinic action. (rxlist.com)
- What are the possible side effects of atropine and diphenoxylate (Lomocot, Lomotil, Vi-Atro)? (rxlist.com)
- To conduct a meta-analysis on the effects of atropine in slowing myopia progression and to compare Asian and white children and randomized controlled trials (RCTs) and observational studies. (nih.gov)
- Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. (wikipedia.org)
- Belladonna/phenobarbital is an oral medication which combines naturally occurring belladonna alkaloids ( atropine , scopolamine [ Transderm-Scop ], and hyoscyamine ) with phenobarbital. (medicinenet.com)
- Atropine and pralidoxime may also be used for purposes not listed in this medication guide. (rexhealth.com)
- Overdose may occur if you receive atropine and pralidoxime but you have not actually been exposed to the specific poisons this medication is designed to treat. (rexhealth.com)
- Atropine can decrease sweating and you may be more prone to heat stroke for a short time after receiving this medication. (rexhealth.com)
- Our Atropine Sulfate Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
- Atropine is an anticholinergic medication that may be administered in a variety of medical situations. (livestrong.com)
- Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if you have used too much atropine ophthalmic, or if anyone has accidentally swallowed the medication. (wellspan.org)
- The purpose of this study is to compare heart rate in infants who receive atropine as a part of their medication before intubation to those who do not. (clinicaltrials.gov)
- Troops who are likely to be attacked with chemical weapons often carry autoinjectors with atropine and an oxime, for rapid injection into the muscles of the thigh. (wikipedia.org)
- Atropine Sulfate Injection, USP is a sterile, isotonic solution of Atropine Sulfate in Water for Injection q.s. (nih.gov)
- Atropine Sulfate Injection is an antimuscarinic agent used to treat bradycardia (low heart rate), reduce salivation and bronchial secretions before surgery, as an antidote for overdose of cholinergic drugs or mushroom poisoning. (rxlist.com)
- Atropine is a drug obtained from belladonna that is administered via injection, eye drops, or in oral form to relax muscles by inhibiting nerve responses. (medical-library.net)
- Hospira's Atropine Sulfate Injection is available in three different configurations, including Abboject ™ glass syringes or Ansyr™ plastic syringes. (buyemp.com)
- To investigate the effects of repeated atropine injection on heart rate (HR) variability in resting Thoroughbred horses, two μg/kg of atropine as parasympathetic nervous blockade was injected intravenously every 6 min to a total of 8 μg/kg after intravenous administration of 0.2 mg/kg of propranolol as sympathetic nervous blockade. (go.jp)
- Large doses of atropine can cause hallucination. (encyclopedia.com)
- All doses of atropine appear similarly effective, while higher doses have greater side effects. (wikipedia.org)
- In poisoning by the organic phosphate cholinesterase inhibitors found in certain insecticides and by chemical warfare "nerve gases", large doses of atropine relieve the muscarine-like symptoms and some of the central-nervous-system manifestations. (nih.gov)
- Doses of 0.5 to 1 mg of atropine are mildly stimulating to the central nervous system. (nih.gov)
- Pregnancy Category B. Reproduction studies have been performed in mice in doses of 50 mg/kg of body weight and have revealed no evidence of impaired fertility or harm to the fetus due to Atropine Sulfate. (nih.gov)
- Initial single doses of Atropine Sulfate in adults vary from 0.5 mg to 1 mg (5 - 10 mL of the 0.1 mg/mL solution) for antisialagogue and other antivagal effects, to 2 to 3 mg (20 - 30 mL of the 0.1 mg/mL solution) as an antidote for organophosporous or muscarinic mushroom poisoning. (rxlist.com)
- So Tan and a group of collaborators started testing out different doses of atropine on a group of 400 nearsighted children in Singapore. (cpr.org)
- Type of cholinesterase inhibitor toxicity that may require extremely high doses of atropine. (cdc.gov)
- 2002) Thus, even when given sufficient doses of atropine, patients may need artificial ventilation, sometimes for weeks. (cdc.gov)
- Some cases of mild to moderate poisonings may improve with these doses of atropine. (cdc.gov)
- Victims of organophosphate poisoning can tolerate large doses (1000 mg) of atropine. (ocfl.net)
- ATOM 26 followed to compare the efficacy and tolerance of lower doses of atropine. (mivision.com.au)
- Atropine doses of 0.5%, 0.1% or 0.01% were given bilaterally, nightly over a two year period. (mivision.com.au)
- Myopia progression in the atropine 0.01% group was -0.49D compared with the untreated group in ATOM 1 of -1.2D. The higher doses (0.5% and 0.1%) had a greater effect in retarding myopia progression, which was statistically significant compared with 0.01%, however, it was not considered to be clinically significant and the lowest dose was better tolerated. (mivision.com.au)
- Atropine is a type of medicine called an antimuscarinic (or sometimes called an anticholinergic). (netdoctor.co.uk)
- Atropine sulfate an anticholinergic, is endo-(±)- a ( hydroxymethyl) benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1] oct-3-yl ester sulfate (2:1) (salt) monohydrate. (egeneralmedical.com)
- It can produce a psychotic condition named atropine psychosis characterized by dry mouth, blurred vision, forgetfulness, and difficulty with urination triggered by atropine and the anticholinergic effects of other drugs, particularly anti-psychotic medications. (medical-library.net)
- Atropine, an anticholinergic agent, acts as an antagonist on the muscarinic receptors of the sweat glands and inhibits their secretion in a dose-dependent way. (clinicaltrials.gov)
- Atropine is a potent parasympatholytic anticholinergic. (ocfl.net)
- Atropine produces rapid heart rate, dilated pupils, dry skin, and anesthetizes the nerve endings in the skin. (infoplease.com)
- For instance, addicts who abuse smaller amounts of atropine will suffer symptoms such as thirst, dilated pupils, increased heart rate, blurred vision and dry skin. (wedorecover.com)
- ATROPINE (A troe peen) can help treat many conditions. (cvs.com)
- Sustained release tablets: 48.6 mg phenobarbital, 0.311 mg hyoscyamine sulfate, 0.0582 mg atropine sulfate, and 0.0195 mg scopolamine hydrobromide. (medicinenet.com)
Effect of atropine2
Amounts of atropine2
Treatment with atropine3
- you should know that your vision may be blurred during your treatment with atropine ophthalmic ointment. (medlineplus.gov)
- After treatment with atropine and pralidoxime, you may be watched for up to 72 hours to make sure the medicine has been effective and you no longer have any effects of the poison. (cigna.com)
- Some children have residual amblyopia after treatment with atropine eyedrops for amblyopia due to strabismus and/or anisometropia. (nih.gov)
Dilate the pupil3
- Atropine eye drops are used to dilate the pupil and relax the lens so that eye examinations can be carried out thoroughly. (netdoctor.co.uk)
- Ophthalmic atropine is used during eye examinations to dilate the pupil. (medicinenet.com)
- Atropine induces mydriasis by blocking contraction of the circular pupillary sphincter muscle, which is normally stimulated by acetylcholine release, thereby allowing the radial pupillary dilator muscle to contract and dilate the pupil. (bionity.com)
- The lower dose of 0.01% is thus generally recommended due to less side effects and potential less rebound worsening when the atropine is stopped. (wikipedia.org)
- The children getting the lowest dose, eyedrops that were just 0.01 percent atropine, had the least worsening of nearsightedness compared to any other group after a five-year period. (cpr.org)
- And the children on 0.01 percent atropine had almost no uncomfortable side effects from the eyedrops, the researchers reported Monday at the American Academy of Ophthalmology annual meeting in Las Vegas. (cpr.org)
- Right now, only eyedrops with 1 percent atropine are commercially available in the United States, though 0.01 percent is available in places like Hong Kong, where myopia is especially common. (cpr.org)
- They were randomised to either 0.01mg/Kg atropine or placebo. (bestbets.org)
- Currently atropine 0.01% needs to be made at a compound pharmacy and its use for myopia progression is off label. (mivision.com.au)
- Thus atropine causes a rise in heart rate and inhibits secretions (for example of saliva, causing a dry mouth, and of the digestive enzymes). (encyclopedia.com)
- Atropine also stimulates the heart and reduces the secretions of the nose, mouth, and lungs to improve breathing. (rexhealth.com)
- Anaesthesia: Atropine is indicated as an antisialogogue in anaesthetic premedication to reduce or prevent secretions in the respiratory tract. (healthdirect.gov.au)
- Atropine is often used in conjunction with the oxime pralidoxime chloride. (wikipedia.org)
- What is the most important information I should know about atropine and pralidoxime? (rexhealth.com)
- Atropine and pralidoxime is a combination medicine used as an antidote to treat poisoning by a pesticide (insect spray) or a chemical that interferes with the central nervous system, such as nerve gas. (rexhealth.com)
- What should I discuss with my healthcare provider before receiving atropine and pralidoxime? (rexhealth.com)
- How is atropine and pralidoxime given? (rexhealth.com)
- Atropine and pralidoxime is injected into a muscle in your upper thigh. (rexhealth.com)
- Atropine and pralidoxime is usually given as soon as possible after the onset of poisoning symptoms. (rexhealth.com)
- Since atropine and pralidoxime is used when needed, it does not have a daily dosing schedule. (rexhealth.com)
- What should I avoid after receiving atropine and pralidoxime? (rexhealth.com)
- What other drugs will affect atropine and pralidoxime? (rexhealth.com)
- Other drugs may affect atropine and pralidoxime, including prescription and over-the-counter medicines, vitamins, and herbal products. (rexhealth.com)
- Atropine and pralidoxime can pass into breast milk and may harm a nursing baby. (cigna.com)
- In an emergency situation, it may not be possible before you are treated with atropine and pralidoxime to tell your caregivers if you are pregnant or breast-feeding. (cigna.com)
- Since atropine and pralidoxime is given by a healthcare professional in an emergency setting, you are not likely to miss a dose. (cigna.com)
- atropine ăt´rəpēn, -pĭn [ key ] , alkaloid drug derived from belladonna and other plants of the family Solanaceae (nightshade family). (infoplease.com)
- atropine is an alkaloid derived from the solanaceous plants Atropa belladonna ( deadly nightshade ), Hyoscyamus niger (black henbane), and Datura stramonium (thornapple). (encyclopedia.com)
- Atropine is a white crystalline alkaloid which may be extracted from belladonna root and hyoscyamine or may be produced synthetically. (nih.gov)
- Atropine is a tropane alkaloid extracted from the deadly nightshade ( Atropa belladonna ) and other plants of the family Solanaceae . (bionity.com)
- Atropine Sulfate Ophthalmic is a tropane alkaloid, prescribed for dilatation of pupil. (medindia.net)
- Atropine is a tropane alkaloid , that can be extracted from the deadly nightshade ( Atropa belladonna ), mandrake ( Mandragora officinarum ) and certain other plants. (wikipedia.org)
- Atropine is a poisonous alkaloid that occurs naturally in belladonna and several other plants of the nightshade family, Solanaceae . (fsu.edu)
- In refractive and accommodative amblyopia, when occlusion is not appropriate sometimes atropine is given to induce blur in the good eye. (wikipedia.org)
- A randomized trial of adding a plano lens to atropine for amblyopia. (nih.gov)
- 8 years of age (mean, 5.8 years) with stable residual amblyopia (range, 20/32 to 20/160, mean 20/63(+1)) were enrolled after at least 12 weeks of atropine treatment of the fellow eye. (nih.gov)
- A few decades later, people started using atropine to treat amblyopia , or lazy eye, since it blurs the stronger eye's vision and forces the weaker eye to work harder. (cpr.org)
- To compare daily atropine to weekend atropine as prescribed treatments for moderate amblyopia in children younger than 7 years. (nih.gov)
- Weekend atropine provides an improvement in VA of a magnitude similar to that of the improvement provided by daily atropine in treating moderate amblyopia in children 3 to 7 years old. (nih.gov)
- Atropine also has central-nervous system activity, which may be stimulating or depressing depending upon the dose. (nih.gov)
- You may not be able to take atropine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. (cardiosmart.org)
- The usual dose of atropine is 0.5 to 1 mg every three to five minutes, up to a maximum dose of 3 mg. (bionity.com)
- We realized, yeah, atropine does work, but we've got to reduce the dose so we can reduce some of these side effects. (cpr.org)
- Patients whose nearsightedness rebounded during that year went back on the low-dose atropine for another year or two. (cpr.org)
- If low-dose atropine can be made available to more people around the world, then that's likely to reduce the number of people at risk for developing a retinal detachment or retinal degeneration because of extreme nearsightedness. (cpr.org)
- It has been suggested that when these physiological changes do not occur with this dose (sometimes referred to as an atropine challenge ), this is indicative of cholinesterase inhibitor toxicity. (cdc.gov)
- We know that low-dose atropine will work with less rebound after discontinuation, but we also know that stronger atropine works better and faster. (healio.com)
- So, if I see a child who is 6 years old and is already -7 D, I will place that patient on high-dose 1% atropine, and I will give them photochromic transition lenses. (healio.com)
- For a younger child who is only maybe a -3 D, but they are 4 or 5 years old, I will start with a lower-dose atropine and no bifocal lens. (healio.com)
- When results become available, what we are going to know is whether controlled preparation of low-dose atropine is effective in a diverse population. (healio.com)
- The dose of Atropine will be decided by your doctor. (mims.com)
- A 4 year old patient presents to the ED with a lip laceration, you decide to repair it under ketamine sedation and prepare an appropriate dose of ketamine and atropine. (bestbets.org)
- Atropine should be routinely given if high dose IM ketamine is used. (bestbets.org)
- Administration of atropine decreased parasympathetic nervous activity in a dose-dependent manner, affecting first the LF power, then the HF power and finally HR. These responses may provide valuable information for evaluating autonomic nervous activity in Thoroughbred horses. (go.jp)
- We now know that atropine blocks the action of the neurotransmitter acetylcholine at all the nerve endings where the membrane receptors are of the so-called muscarinic type. (encyclopedia.com)
- The circular muscle is under parasympathetic control, so when the transmitter, acetylcholine, is blocked with atropine, the pupil will dilate. (encyclopedia.com)
- However, by blocking the action of acetylcholine at muscarinic receptors, atropine also serves as a treatment for poisoning by organophosphate insecticides and nerve agents, such as tabun (GA), sarin (GB), soman (GD), and VX. (wikipedia.org)
- Atropine can be used to reduce the effect of the poisoning by blocking muscarinic acetylcholine receptors, which would otherwise be overstimulated, by excessive acetylcholine accumulation. (wikipedia.org)
- Atropine blocks the action of acetylcholine, a neurotransmitter that causes the contraction of two types of muscle, smooth and cardiac muscles. (medicinenet.com)
- This occurs because atropine is a competitive antagonist of the muscarinic acetylcholine receptors . (bionity.com)
- By blocking the action of acetylcholine at muscarinic receptors, atropine also serves as an antidote for poisoning by organophosphate insecticides and nerve gases . (bionity.com)
- Atropine blocks the action of chemical called acetylcholine (ah see til KO leen), which may exist in high levels in the body after a poisoning. (cigna.com)
- Atropine inhibits the activity of acetylcholine. (livestrong.com)
- When atropine is introduced to heart cells, it blocks them from being activated by acetylcholine released from the vagus nerve. (livestrong.com)
- The authors speculate that this effect occurs because atropine may transiently increase the amount of acetylcholine available for use by the heart nerves, leading to temporary slowing of the heart rate. (livestrong.com)
- Chemically similar in some regards to acetylcholine, within the body, atropine interferes with the nerve impulses normally conveyed by the neurotransmitter. (fsu.edu)
- Atropine works by competitively occupying muscarinic receptor sites, thus reducing the effects of excessive acetylcholine on these sites brought about by cholinesterase inhibition. (cdc.gov)
- Atropine, derived from Atropa belladonna, blocks the effects of acetylcholine in effector organs supplied by postganglionic cholinergic nerves. (thefreedictionary.com)
- Long-lasting pupillary dilation results if atropine drops are placed in the eye. (encyclopedia.com)
- Atropine eye drops contain the active ingredient atropine, which is a type of medicine called an antimuscarinic. (netdoctor.co.uk)
- Atropine eye Drops contain atropine sulfate which belongs to groups of medicines called mydriatics (medicines that widen the pupil) and cycloplegics (medicines used to relax the muscles which enable the eyes to focus). (netdoctor.co.uk)
- Atropine eye drops are used to prevent painful spasms in the ciliary muscle and to prevent a complication where the iris can stick to the lens. (netdoctor.co.uk)
- Atropine eye drops may also be used to treat a lazy eye in children. (netdoctor.co.uk)
- Atropine eye drops are also used to relax the ciliary muscle in a condition called anterior uveitis. (netdoctor.co.uk)
- Atropine eye drops are used to prevent these problems. (netdoctor.co.uk)
- Bottles of atropine eye drops contain the preservative benzalkonium chloride. (netdoctor.co.uk)
- In clinical studies, use of a single topical administration of atropine 1% ophthalmic solution (eye drops) resulted in maximal mydriasis (pupil dilation or widening) in approximately 40 minutes and maximal cycloplegia in approximately 60 to 90 minutes. (medicinenet.com)
- Do not use atropine eye drops while wearing contact lenses. (wellspan.org)
- The dilemma for pediatric ophthalmologists is whether to offer an off-label treatment, atropine drops, to inhibit axial lengthening when questions remain regarding the best way to use the treatment, how long to use it, whether certain populations benefit more, how to balance costs, and how best to present advice and counsel to patients. (healio.com)
- Commonly found in the form of a white tablet, atropine can also be found as eye drops as well as an ointment. (wedorecover.com)
- The patients in the study were randomised to receive either atropine 1% or placebo drops in one eye over two years. (mivision.com.au)
- The Notice of Intent to Revise posted on August 31, 2018 incorrectly identified the monograph revision being proposed as Atropine Sulfate Ophthalmic Ointment. (uspnf.com)
Needed With Ketamine Sedation1
- Is Atropine Needed With Ketamine Sedation? (clinicaltrials.gov)
- Ophthalmic atropine is used before eye examinations to dilate (open) the pupil, the black part of the eye through which you see. (medlineplus.gov)
- By blocking the muscarinic receptors in the eye, atropine causes the pupil to dilate. (netdoctor.co.uk)
- When you stop using atropine as part of a treatment programme it can take about a week for pupil size in the treated eye to return to normal. (netdoctor.co.uk)
- Atropine sulfate relaxes the ciliary muscle, which controls the shape of the eye's lens as it focuses, and another eye muscle called the sphincter, which controls the narrowing and widening of the pupil. (wholehealthmd.com)
- Atropine degrades slowly, typically wearing off in 2 to 3 days, so tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) are generally preferred as mydriatics. (bionity.com)
- At the end of an investigation into the death of Palestinian woman Jawaher Abu-Rahma over two weeks ago in Bilin, the IDF determined Wednesday that she died from an overdose of Atropine administered at the hospital. (ynetnews.com)
- An overdose of atropine and diphenoxylate can be fatal to a child. (cigna.com)
- An overdose of atropine and diphenoxylate can cause breathing problems and may result in death or permanent brain damage. (cigna.com)
- If there is chronic use or an overdose of atropine, the heart may beat too fast. (livestrong.com)
Davis's Drug Guide1
- atropine† is a topic covered in the Davis's Drug Guide . (unboundmedicine.com)
Allergic to atropine1
- tell your doctor and pharmacist if you are allergic to atropine, belladonna, or any other drugs. (medlineplus.gov)
Known whether atropine2
- Atropine relieves these symptoms by relaxing the muscle. (netdoctor.co.uk)
- Atropine is given as an antidote to SLUD GE ( Salivation , Lacrimation , Urination , Diaphoresis , Gastrointestinal motility, Emesis ) symptoms caused by organophosphate poisoning. (bionity.com)
- Check for signs and symptoms of atropine toxicity (e.g. fever, muscle fasciculations, delirium, and mental status). (mims.com)
- To our knowledge, this is the first report of acute atropine intoxications with psychiatric symptoms secondary to Pulmonaria officinalis in several members of a family. (isciii.es)
- We suggest this recommendation to be extended to patients who attend Accident and Emergency facilities and we here present a series of case vignettes in which three members of the same family manifested both somatic and psychiatric symptoms consistent with atropine intoxication after consuming an herbal infusion made with Pulmonaria Officinalis . (isciii.es)
- The 14-year-old granddaughter began to experience atropine symptoms two hours after the first infusion of Pulmonaria Officinalis was taken for treating a common cold. (isciii.es)
- Below you can find out more about atropine addiction, what the signs and symptoms are as well as how it can be treated. (wedorecover.com)
- Addicts who use excessive use of atropine may experience all of the above symptoms as well as migraines, restlessness, swallowing problems, disillusionment and over-excitement. (wedorecover.com)
- Available either as the tincture or extract of belladonna, or as the pure substance atropine sulfate, it is a depressant of the parasympathetic nervous system . (infoplease.com)
- Generally, atropine lowers the "rest and digest" activity of all muscles and glands regulated by the parasympathetic nervous system. (bionity.com)
- One of the main actions of the parasympathetic nervous system is to stimulate the M 2 muscarinic receptor in the heart, but atropine inhibits this action. (bionity.com)
- Do not take atropine without first talking to your doctor if you are pregnant. (cardiosmart.org)
- Do not take atropine without first talking to your doctor if you are breast-feeding a baby. (cardiosmart.org)
- How should I take atropine? (cardiosmart.org)
- Take atropine exactly as directed by your doctor. (cardiosmart.org)
- Can I take Atropine Sulfate Min-I-Jet (CSL) in sport? (healthdirect.gov.au)
- Take Atropine exactly as directed by your doctor or according to the instructions on the label. (mims.com)
- Some pharmacies use injectable atropine and dilute it. (healio.com)
Myopia Progression in Children2
- Randomized controlled trials and observational studies that assessed the effects of all concentrations of atropine in slowing myopia progression in children were searched from MEDLINE, EMBASE, and the Cochrane Library up to April 2013. (nih.gov)
- Atropine could significantly slow myopia progression in children, with greater effects in Asian than in white children. (nih.gov)
- Atropine occurs naturally in a number of plants of the nightshade family, including deadly nightshade (belladonna), Jimson weed, and mandrake. (wikipedia.org)
- The drug is atropine, one of the toxins in deadly nightshade and jimsonweed. (cpr.org)
- Belladonna is obtained from the dried leaves of Atropa belladonna, also known as deadly nightshade, or of Atropa acuminata, a source of alkaloids that are converted to atropine. (thefreedictionary.com)
- In accordance with section 7.04 (c) of the 2015-2020 Rules and Procedures of the Council of Experts, this is to provide notice that the Chemical Medicines Monographs 4 Expert Committee intends to revise the Atropine Sulfate Ophthalmic Ointment monograph. (uspnf.com)
- Atropine is used to treat the rigidity, tremor, excessive salivation, and sweating caused by Parkinson's disease. (cardiosmart.org)
- It is important that the patient be adequately oxygenated and ventilated prior to using atropine, as atropine may precipitate ventricular fibrillation in a poorly oxygenated patient. (ocfl.net)
Improving visual acuity1
- Evidence suggests that atropine penalization is just as effective as occlusion in improving visual acuity. (wikipedia.org)
- Which drugs or supplements interact with atropine sulfate ointment-ophthalmic? (medicinenet.com)
- Does Atropine SULFATE Syringe interact with other drugs you are taking? (webmd.com)
- Atropine Sulfate may interact with other drugs. (rxlist.com)
- Although it is not likely that other drugs you take orally or inject will have an effect on atropine used in the eyes, many drugs can interact with each other. (everydayhealth.com)
- This list does not include all medicines that may interact with Atropine. (mims.com)
- As early as the 1990s, doctors had some evidence that atropine can slow the progression of nearsightedness. (cpr.org)
- That opens atropine back up as a practical treatment for myopia, Epley says, "This gives us a tool to slow down that progression of myopia that we didn't have in a safe way before. (cpr.org)
- Myopia progression is a hot topic in pediatric ophthalmology, whether the treating physician uses atropine, surgical procedures or contact lenses. (healio.com)
- Atropine can effectively slow the progression of myopia for many patients, however there is much to be learnt about how this therapy acts and when and how it should be used. (mivision.com.au)
- Atropine, a nonselective muscarinic antagonist, has been at the forefront of the pharmacological interventions of myopia progression. (mivision.com.au)
- 3 Studies on topical atropine use were published in the 1960s and 1970s, 4 however, it was the atropine for the treatment of myopia studies (ATOM) 5,6 which consolidated interest in the use of atropine to retard the progression of myopia in children. (mivision.com.au)
- It is unclear how atropine retards axial length growth and therefore myopia progression in childhood. (mivision.com.au)
- Atropine comes as a solution (liquid) to instill in the eyes and an eye ointment to apply to the eyes. (medlineplus.gov)
- What is atropine sulfate ointment-ophthalmic, and how does it work (mechanism of action)? (medicinenet.com)
- What brand names are available for atropine sulfate ointment-ophthalmic? (medicinenet.com)
- Is atropine sulfate ointment-ophthalmic available as a generic drug? (medicinenet.com)
- Do I need a prescription for atropine sulfate ointment-ophthalmic? (medicinenet.com)
- Is atropine sulfate ointment-ophthalmic safe to take if I'm pregnant or breastfeeding? (medicinenet.com)
- What else should I know about atropine sulfate ointment-ophthalmic? (medicinenet.com)
- What preparations of atropine sulfate ointment-ophthalmic are available? (medicinenet.com)
- How should I keep atropine sulfate ointment-ophthalmic stored? (medicinenet.com)
- Injections of atropine are used in the treatment of symptomatic or unstable bradycardia. (wikipedia.org)
- Injections of atropine are used in the treatment of bradycardia (an extremely low heart rate), asystole and pulseless electrical activity (PEA) in cardiac arrest . (bionity.com)
- During anaesthesia, atropine may be used to prevent reflex bradycardia and restore cardiac rate and arterial pressure resulting from the increased vagal activity associated with laryngoscopy, tracheal intubation and intra-abdominal manipulation, and for the prevention of the oculo-cardiac reflex during ophthalmic surgery. (healthdirect.gov.au)
- Atropine occurs naturally and is extracted from belladonna alkaloids contained in plants. (medicinenet.com)
- Parenteral atropine is not generally recommended for those whose sole manifestation of toxicity is miosis (pupillary constriction). (cdc.gov)
- Atropin er eit lækjemiddel som vert framstelt av belladonnaplanta (Atropa Belladonna) og er ein potensielt giftig medisinsk urt. (wikipedia.org)
- Although atropine poisoning has occasionally occurred following overdosage with suicidal intent, and after the ingestion of wild berries of Atropa belladonna , the great majority of reported cases have been therapeutic accidents, resulting from carelessness on the part of physicians, pharmacists, patients and unskilled hospital aides. (annals.org)
- Latinsk rodov n zev Atropa je odvozen od jm na ne prosn eck bohyn osudu Atropos, kter p est h v nit ivota, latinsk druhov jm no bella-donna znamen "p vabn pan ", proto e vzne en italsk d my v ily, e zasn n pohled je zn mkou okouzluj c kr sy. (referaty-seminarky.cz)
- Atropine is a core medicine in the World Health Organization 's " Essential Drugs List ", which is a list of minimum medical needs for a basic health care system. (wikipedia.org)
- One of the chief reasons for the decrease in the popularity of atropine for some purposes is the wide array of effects produced by the drug, the medical community increasingly coming to favor synthetic drugs that generate a similar, but narrower, range of corollaries. (fsu.edu)
- Scopolamine and atropine have very similar actions. (encyclopedia.com)
- Atropine is contraindicated in patients predisposed to narrow angle glaucoma . (bionity.com)
- Some medicines can affect how difenoxin/atropine works. (limamemorial.org)
- The authors of a 2004 study published in the journal 'Continuing Education in Anesthesia, Critical Care and Pain' reported that atropine may temporarily lower heart rate before an increase occurs. (livestrong.com)