Atrioventricular Node
Tachycardia, Atrioventricular Nodal Reentry
Abnormally rapid heartbeats caused by reentry of atrial impulse into the dual (fast and slow) pathways of ATRIOVENTRICULAR NODE. The common type involves a blocked atrial impulse in the slow pathway which reenters the fast pathway in a retrograde direction and simultaneously conducts to the atria and the ventricles leading to rapid HEART RATE of 150-250 beats per minute.
Bundle of His
Small band of specialized CARDIAC MUSCLE fibers that originates in the ATRIOVENTRICULAR NODE and extends into the membranous part of the interventricular septum. The bundle of His, consisting of the left and the right bundle branches, conducts the electrical impulses to the HEART VENTRICLES in generation of MYOCARDIAL CONTRACTION.
Heart Conduction System
Sinoatrial Node
The small mass of modified cardiac muscle fibers located at the junction of the superior vena cava (VENA CAVA, SUPERIOR) and right atrium. Contraction impulses probably start in this node, spread over the atrium (HEART ATRIUM) and are then transmitted by the atrioventricular bundle (BUNDLE OF HIS) to the ventricle (HEART VENTRICLE).
Heart Block
Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
Catheter Ablation
Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.
Cardiac Pacing, Artificial
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Lymph Nodes
Electrophysiologic Techniques, Cardiac
Tachycardia
Wolff-Parkinson-White Syndrome
A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.
Tachycardia, Supraventricular
Tachycardia, Ectopic Junctional
A rare form of supraventricular tachycardia caused by automatic, not reentrant, conduction initiated from sites at the atrioventricular junction, but not the ATRIOVENTRICULAR NODE. It usually occurs during myocardial infarction, after heart surgery, or in digitalis intoxication with a HEART RATE ranging from 140 to 250 beats per minute.
Atrial Fibrillation
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Electrocoagulation
Procedures using an electrically heated wire or scalpel to treat hemorrhage (e.g., bleeding ulcers) and to ablate tumors, mucosal lesions, and refractory arrhythmias. It is different from ELECTROSURGERY which is used more for cutting tissue than destroying and in which the patient is part of the electric circuit.
Sick Sinus Syndrome
A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.
Atrial Flutter
Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).
Refractory Period, Electrophysiological
The period of time following the triggering of an ACTION POTENTIAL when the CELL MEMBRANE has changed to an unexcitable state and is gradually restored to the resting (excitable) state. During the absolute refractory period no other stimulus can trigger a response. This is followed by the relative refractory period during which the cell gradually becomes more excitable and the stronger impulse that is required to illicit a response gradually lessens to that required during the resting state.
Ultimobranchial Body
A diverticulum from the fourth pharyngeal pouch of an embryo, regarded by some as a rudimentary fifth pharyngeal pouch and by others as a lateral thyroid primordium. The ultimobranchial bodies of lower vertebrates contain large amounts of calcitonin. In mammals the bodies fuse with the thyroid gland and are thought to develop into the parafollicular cells. (Stedman, 25th ed)
Heart Septum
Tachycardia, Ectopic Atrial
Abnormally rapid heartbeats originating from one or more automatic foci (nonsinus pacemakers) in the HEART ATRIUM but away from the SINOATRIAL NODE. Unlike the reentry mechanism, automatic tachycardia speeds up and slows down gradually. The episode is characterized by a HEART RATE between 135 to less than 200 beats per minute and lasting 30 seconds or longer.
Rabbits
Electrophysiology
Pacemaker, Artificial
Vagus Nerve
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Radio Waves
Electromagnetic waves with frequencies between about 3 kilohertz (very low frequency - VLF) and 300,000 megahertz (extremely high frequency - EHF). They are used in television and radio broadcasting, land and satellite communications systems, radionavigation, radiolocation, and DIATHERMY. The highest frequency radio waves are MICROWAVES.
Atrioventricular Block
Anti-Arrhythmia Agents
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Purkinje Fibers
Dogs
Arrhythmias, Cardiac
Heart Ventricles
Action Potentials
Connexins
Body Surface Potential Mapping
Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)
Lymph Node Excision
Follow-Up Studies
Heart Neoplasms
Microelectrodes
Models, Cardiovascular
Tricuspid Valve
Sentinel Lymph Node Biopsy
Myocardium
A comparison of an A1 adenosine receptor agonist (CVT-510) with diltiazem for slowing of AV nodal conduction in guinea-pig. (1/783)
1. The purpose of this study was to compare the pharmacological properties (i.e. the AV nodal depressant, vasodilator, and inotropic effects) of two AV nodal blocking agents belonging to different drug classes; a novel A1 adenosine receptor (A1 receptor) agonist, N-(3(R)-tetrahydrofuranyl)-6-aminopurine riboside (CVT-510), and the prototypical calcium channel blocker diltiazem. 2. In the atrial-paced isolated heart, CVT-510 was approximately 5 fold more potent to prolong the stimulus-to-His bundle (S-H interval), a measure of slowing AV nodal conduction (EC50 = 41 nM) than to increase coronary conductance (EC50 = 200 nM). At concentrations of CVT-510 (40 nM) and diltiazem (1 microM) that caused equal prolongation of S-H interval (approximately 10 ms), diltiazem, but not CVT-510, significantly reduced left ventricular developed pressure (LVP) and markedly increased coronary conductance. CVT-510 shortened atrial (EC50 = 73 nM) but not the ventricular monophasic action potentials (MAP). 3. In atrial-paced anaesthetized guinea-pigs, intravenous infusions of CVT-510 and diltiazem caused nearly equal prolongations of P-R interval. However, diltiazem, but not CVT-510, significantly reduced mean arterial blood pressure. 4. Both CVT-510 and diltiazem prolonged S-H interval, i.e., slowed AV nodal conduction. However, the A1 receptor-selective agonist CVT-510 did so without causing the negative inotropic, vasodilator, and hypotensive effects associated with diltiazem. Because CVT-510 did not affect the ventricular action potential, it is unlikely that this agonist will have a proarrythmic action in ventricular myocardium. (+info)Modulation of AV nodal and Hisian conduction by changes in extracellular space. (2/783)
Previous studies have demonstrated that the extracellular space (ECS) component of the atrioventricular (AV) node and His bundle region is larger than the ECS in adjacent contractile myocardium. The potential physiological significance of this observation was examined in a canine blood-perfused AV nodal preparation. Mannitol, an ECS osmotic expander, was infused directly into either the AV node or His bundle region. This resulted in a significant dose-dependent increase in the AV nodal or His-ventricular conduction time and in the AV nodal effective refractory period. Mannitol infusion eventually resulted in Wenckebach block (n = 6), which reversed with mannitol washout. The ratio of AV nodal to left ventricular ECS in tissue frozen immediately on the development of heart block (n = 8) was significantly higher in the region of block (4.53 +/- 0.61) compared with that in control preparations (2.23 +/- 0.35, n = 6, P < 0.01) and donor dog hearts (2.45 +/- 0.18, n = 11, P < 0.01) not exposed to mannitol. With lower mannitol rates (10% of total blood flow), AV nodal conduction times increased by 5-10% and the AV node became supersensitive to adenosine, acetylcholine, and carbachol, but not to norepinephrine. We conclude that mannitol-induced changes in AV node and His bundle ECS markedly alter conduction system electrophysiology and the sensitivity of conductive tissues to purinergic and cholinergic agonists. (+info)Ventricular excitation maps using tissue Doppler acceleration imaging: potential clinical application. (3/783)
OBJECTIVES: The purpose of this study is to validate the use of tissue Doppler acceleration imaging (TDAI) for evaluation of the onset of ventricular contraction in humans. BACKGROUND: Tissue Doppler acceleration imaging can display the distribution, direction and value of ventricular acceleration responses to myocardial contraction and electrical excitation. METHODS: Twenty normal volunteers underwent TDAI testing to determine the normal onset of ventricular acceleration. Two patients with paroxysmal supraventricular tachycardia and 30 patients with permanent pacemakers underwent introduction of esophageal and right ventricular pacing electrodes, respectively, and were studied to visualize the onset of pacer-induced ventricular acceleration. Eight patients with dual atrioventricular (AV) node and 20 patients with Wolff-Parkinson-White (WPW) syndrome underwent TDAI testing to localize the abnormal onset of ventricular acceleration, and the results were compared with those of intracardiac electrophysiology (ICEP) tests. RESULTS: The normal onset and the onset of dual AV node were localized at the upper interventricular septum (IVS) under the right coronary cusp within 25 ms before the beginning of the R wave in the electrocardiogram (ECG). In all patients in the pacing group, the location and timing of the onset conformed to the positions and timing of electrodes (100%). In patients with WPW syndrome, abnormal onset was localized to portions of the ventricular wall other than the upper IVS at the delta wave or within 25 ms after the delta wave in the ECG. The agreement was 90% (18 of 20) between the abnormal onset and the position of the accessory pathways determined by ICEP testing. CONCLUSIONS: These results suggest that TDAI is a useful noninvasive method that frequently is successful in visualizing the intramural site of origin of ventricular mechanical contraction. (+info)Anatomical study of truncus arteriousus communis with embryological and surgical considerations. (4/783)
Twelve specimens of truncus arteriosus communis have been studied anatomically, with special reference to the conal anatomy and to the associated cardiac anomalies which can create additional problems if surgical repair is planned. A wide spectrum of conal morphology has been observed, suggesting that differential conal absorption is a developmental characteristic of truncus arteriousus as well as of transposition complexes. The invariable absence of septation of the ventricular infundibula and semilunar valves, in spite of the variable anatomy of the free wall of the conus, indicates that all types of truncus arteriosus, ontogenetically, should be considered as a single undivided conotruncus. Various types of ventircular septal defect were found: (a) ventricular septal defect with absent crista, in which no remnants of conal septum are present; (b) supracristal ventricular septal defect, in which vestigial conal septum is seen in front of the membranous septum; (c) bulloventricular foramen, associated with univentricular origin of the truncus from the right ventricle. Frequent associated anomalies are underdevelopment of the aortic arch, truncal valve malformations, and obstructive ventricular septal defect. The AV conduction system studied in one case showed an arrangement similar to Fallot's tetralogy with the His bundle and the left bundle-branch in a safe position behind the posteroinferior rim of the defect. The postoperative fate of the frequently abnormal truncal valve and the theoretical indications for total repair for Type IV truncus are also discussed. (+info)Electrophysiological effects of mexiletine in man. (5/783)
The electrophysiological effects of intravenous mexiletine in a dose of 200 to 250 mg given over 5 minutes, followed by continuous infusion of 60 to 90 mg per hour, were studied in 5 patients with normal conduction and in 20 patients with a variety of disturbances of impulse formation and conduction, by means of His bundle electrography, atrial pacing, and the extrastimulus method. In all but 2 patients the plasma level was above the lower therapeutic limit. Mexiletine had no consistent effects on sinus frequency and atrial refractoriness. The sinoatrial recovery time changed inconsistently in both directions; however, of the 5 patients in whom an increase was evident, 3 had sinus node dysfunction. In most patients mexiletine increased the AV nodal conduction time at paced atrial rates and shifted the Wenckebach point to a lower atrial rate. The effective refractory period of the AV node was not consistently influenced, while the functional refractory period increased in 12 out of 14 patients. The HV intervals increased by a mean of 11 ms in 8 patients and were unchanged in 17. Both the relative and effective refractory period of the His-Purkinje system increased after mexiletine. Non-cardiac side effects occurred in 7 out of 25 patients, and cardiac side effects, including one serious, in 2. The results indicate that mexiletine shares some electrophysiological properties with procainamide and quinidine, when given to patients with conduction defects, and that the drug should not be used in patients with pre-existing impairment of impulse formation or conduction. It has additional effects on AV nodal conduction which may be of value in the treatment of re-entrant tachycardias involving the AV node. (+info)Monophasic action potentials of right atrium and electrophysiological properties of AV conducting system in patients with hypothyroidism. (6/783)
In 12 patients with manifest hypothyroidism right atrial monophasic action potentials showed a significant prolongation in comparison with data from normal or euthyroid patients. Atrial effective refractory periods were also significantly prolonged. After thyroid treatment the monophasic action potential duration and the effective refractory period of the right atrium were within normal ranges. In 6 hypothyroid patients studies of AV conduction with the aid of His bundle electrography and atrial pacing showed a supraHisian conduction delay which was manifest in one case and latent in another two. InfraHisian conduction delay was encountered in 2 cases. (+info)The nerve supply and conducting system of the human heart at the end of the embryonic period proper. (7/783)
The nerve supply and conducting system were studied in a stage 23 human embryo of exceptional histological quality. The nerves on the right side arose from cervical sympathetic and from cervical and thoracic vagal filaments. Out of their interconnexions vagoxympathetic nerves emerged, which (1) sent a branch in front of the trachea to the aorticopulmonary ganglion, thereby supplying arterial and venous structures, and (2) formed the right sinal nerve, which supplied the sinu-atrial node, and gave filaments to the interatrial septum which could be traced to the atrioventricular node and pulmonary veins. The nerves on the left side arose similarly from cervical sympathetic and from cervical and thoracic vagal filaments. These formed several descending, ganglionated, vagosympathetic filaments that descended to the right of the arch of the aorta and entered the aorticopulmonary ganglion. Filaments leaving the ganglion supplied the pulmonary trunk, ascending aorta, interatrial septum, pulmonary veins, and, as the left sinal nerve, the fold of the left vena cava. The thoracic vagal filaments descended to the left of the arch of the aorta and supplied chiefly the arterial end of the heart. No thoracic sympathetic cardiac filaments were found. The sinu-atrial node began as a crescentic mass in front of the lower part of the superior vena cava. It gradually extended on each side of the superior vena cava and came to form its posterior wall at a more caudal level. The atrial myocardium that formed the septum spurium, venous valves, and interatrial septum could be traced from the sinu-atrial to the atrioventricular node. Myocardium also encircled the atrial aspects of the atrioventricular orifices, and could be traced caudally to the atrioventricular nde. The atrioventricular node was a conspicuous mass in the anterior and lower part of the interatrial septum, from which a clearly defined bundle left to enter the interventricular septum. Right and left limbs were observed, the former being a rounded bundle that passed immediately in front of the root of the aorta. (+info)Atrioventricular nodal conduction during atrial fibrillation: role of atrial input modification. (8/783)
BACKGROUND: Posteroseptal ablation of the atrioventricular node (AVN) has been proposed as a means to slow the ventricular rate during atrial fibrillation (AF). The suggested mechanism is elimination of the AVN "slow pathway." On the basis of the unpredictable success of the procedure, we hypothesize that, in fact, the slow pathway is preserved. Therefore, the slowing of the ventricular rate results from reduced bombardment of the AVN. METHODS AND RESULTS: In 8 rabbit heart atrial-AVN preparations, cooling of the posterior and/or the anterior AVN approaches revealed nonspecific effects on the slow and fast pathway portions of the AVN conduction curve. In 13 other preparations, simulated AF during posterior cooling (n=6) prolonged the His-His (H-H) intervals but did not reveal specific slow pathway injury. In the remaining 7 preparations, AF was applied before and after posteroseptal surgical cuts. During AF with posterior origin, the cuts resulted in longer mean H-H along with slowing of the AVN bombardment rate. However, there was no change in the minimum observed H-H, suggesting an intact slow pathway. During AF with anterior origin, the mean and the shortest H-H remained unchanged before and after the cuts in all preparations. This was associated with the maintenance of high-rate AVN bombardment. CONCLUSIONS: Posteroseptal ablation does not eliminate the slow pathway. Ventricular rate slowing can be obtained if the ablation procedure results in a posteroanterior intra-atrial block leading to a reduction of the rate of AV nodal bombardment. (+info)
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AV Node Ablation
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Atrioventricular node
The atrioventricular node or AV node electrically connects the heart's atria and ventricles to coordinate beating in the top of ... This activates the AV node. The atrioventricular node delays impulses by approximately 0.09s. This delay in the cardiac pulse ... November 2007). "Abnormal Conduction and Morphology in the Atrioventricular Node of Mice With Atrioventricular Canal-Targeted ... Atrioventricular nodal re-entry tachycardia, which is caused by a dual AV node physiology and AVNRT can only occur in people ...
Common ostrich
The atrioventricular node position differs from other fowl. It is located in the endocardium of the atrial surface of the right ... 10 (1): 21-7. Parto P. (2012). "The Structure of the Atrioventricular Node in the Heart of the Female Laying Ostrich (Struthio ... The AV node connects the atrial and ventricular chambers. It functions to carry the electrical impulse from the atria to the ... The sinoatrial node shows a small concentration of Purkinje fibers, however, continuing through the conducting pathway of the ...
Chronotropic
A dromotrope affects atrioventricular node (AV node) conduction. A positive dromotrope increases AV nodal conduction, and a ... such as by changing the rhythm produced by the sinoatrial node. Positive chronotropes increase heart rate; negative ...
Concealed conduction
In this circumstance, an alteration in the F-wave to QRS relationship is seen.[citation needed] Atrioventricular node ... However, this AV node stimulation can cause a delay in subsequent AV conduction by modifying the AV node's subsequent ... As a result of the rapid atrial rate, some of the atrial activity fails to get through the AV node in an antegrade direction ... because the retrograde impulse from the PVC does not completely penetrate the AV node. ...
Lyme disease
"Fatal Lyme carditis and endodermal heterotopia of the atrioventricular node". Postgraduate Medical Journal. 66 (772): 134-6. ... Lyme carditis in 19-87% of people adversely impacts the heart's electrical conduction system, causing atrioventricular block ...
Cystic tumour of the atrioventricular nodal region
It is also known as mesothelioma of the atrioventricular node. It may present as a cardiac arrhythmia or as sudden cardiac ... tumour of the atrioventricular nodal region is a very rare tumour of the heart in the region of the atrioventricular node. ... Cystic tumours of the atrioventricular nodal region, true to their name, have cystic spaces, which are lined by a single layer ... Apr 2000). "Cystic tumour of the atrioventricular nodal region: report of a case successfully treated with surgery". Heart. 83 ...
Arrhythmia
SA node). The impulse initially causes both atria to contract, then activates the atrioventricular node (AV node), which is ... Rhythms produced by an ectopic focus in the atria, or by the atrioventricular node, are the least dangerous dysrhythmias; but ... Bradyarrhythmias are due to sinus node dysfunction or atrioventricular conduction disturbances. Arrhythmias are due to problems ... These cells are found in the conduction system of the heart and include the SA node, AV node, Bundle of His, and Purkinje ...
List of pathologists
Ludwig Aschoff (1866-1942), German pathologist, discoverer of the Aschoff body and the Atrioventricular node in the heart. Max ... discoverer of the Atrioventricular node. Donald Teare (1911-1979), British pathologist. Jacques-René Tenon (1724-1816), French ... Louis-Antoine Ranvier (1835-1922), French physician, pathologist, anatomist and histologist, discoverer of nodes of Ranvier. ...
Supraventricular tachycardia
These abnormal rhythms start from either the atria or atrioventricular node. They are generally due to one of two mechanisms: ... Sinoatrial node reentrant tachycardia (SANRT) is caused by a reentry circuit localised to the SA node, resulting in a P-wave of ... Cryoablation is a newer treatment involving the AV node directly. SVT involving the AV node is often a contraindication to ... at the atrioventricular node, which allows only a proportion of the fast impulses to pass through to the ventricles. An ...
Cardiac muscle
Pacemaker cells in the sinoatrial node, and atrioventricular node are smaller and conduct at a relatively slow rate between the ... Other pacemaker cells are found in the atrioventricular node (secondary pacemaker). Pacemaker cells carry the impulses that are ... ISBN 0-13-193480-5. Kashou AH, Basit H, Chhabra L (January 2020). "Physiology, Sinoatrial Node (SA Node)". StatPearls. PMID ... They are located in the sinoatrial node (the primary pacemaker) positioned on the wall of the right atrium, near the entrance ...
SCN5A
In contrast, expression is low in the sinoatrial node and atrioventricular node. Within the heart, a transmural expression ...
CLIP4
Additionally, high degrees of transcription occur in the adrenal cortex and atrioventricular node. The Human Protein Atlas ... CLIP4 mRNA expression occurs largely in the adrenal cortex and atrioventricular node. The literature encompassing CLIP4's ...
Chordae tendineae
The apex of Koch's triangle is the location of the atrioventricular node. During atrial systole, blood flows from the atria to ... Chordae tendineae are relaxed because the atrioventricular valves are forced open. When the ventricles of the heart contract in ... The chordae tendineae connect the atrioventricular valves (tricuspid and mitral), to the papillary muscles within the ...
Junctional rhythm
Current then passes from the atria through the atrioventricular node and into the bundle of His, from which it travels along ... When this happens, the heart's atrioventricular node takes over as the pacemaker. In the case of a junctional rhythm, the atria ... Retrograde P waves refers to the depolarization from the AV node back towards the SA node. Accelerated junctional rhythm is ... an abnormal heart rhythm resulting from impulses coming from a locus of tissue in the area of the atrioventricular node, the " ...
Muscarinic antagonist
In the atrioventricular node, the resting potential is lowered, which facilitates conduction. This is seen as a shortened PR- ... It causes tachycardia by blocking vagal effects on the sinoatrial node. Acetylcholine hyperpolarizes the sinoatrial node; this ...
Atrial septal defect
"Preoperative secundum atrial septal defect with coexisting sinus node and atrioventricular node dysfunction". Circulation. 65 ( ... Both of these can cause an increased distance of internodal conduction from the SA node to the AV node. In addition to the PR ... but it is more commonly classified as an atrioventricular septal defect. Ostium primum defects are less common than ostium ...
Atrioventricular nodal branch
The atrioventricular nodal branch is a coronary artery that feeds the atrioventricular node, necessary for the excitation of ... The atrioventricular nodal branch supplies the atrioventricular node, allowing for excitation of the ventricles. Coronary ... In approximately 2% of people, the vascular supply to the atrioventricular node arises from both the right coronary artery and ... The artery of the atrioventricular node: an anatomic study based on 38 injection-dissections. Surg Radiol Anat 1996;18:183-187 ...
Koch's triangle
... and septal leaflet of the right atrioventricular valve. It is anatomically significant because the atrioventricular node is ... "Koch's Triangle and the Atrioventricular Node in Ebstein's Anomaly: Implications for Catheter Ablation". Revista Española de ...
Ludwig Aschoff
Together they discovered and described the atrioventricular node (AV node, Aschoff-Tawara node). Numerous travels abroad, to ...
Atrium (heart)
The atrioventricular node (AV node) is another node in the cardiac electrical conduction system. This is located between the ... The sinoatrial (SA) node is located in the posterior aspect of the right atrium, next to the superior vena cava. This is a ... The blood in the atria is pumped into the heart ventricles through the atrioventricular valves. There are two atria in the ... left atrioventricular valve) for pumping out through the aorta for systemic circulation. The right atrium and ventricle are ...
Systole
These electrical pathways contain the sinoatrial node, the atrioventricular node, and the Purkinje fibers. (Exceptions such as ... The electrical activity of ventricular systole is coordinated by the atrioventricular node, which is a discrete collection of ... The sinoatrial node (S-A Node) is the heart's natural pacemaker, issuing electrical signaling that travels through the heart ... the signals of which then coalesce at the atrioventricular node, there to be organized to provide a rhythmic electrical pulse ...
Bundle branches
Widran J, Lev M (December 1951). "The dissection of the atrioventricular node, bundle and bundle branches in the human heart". ...
Adenosine
When it is administered intravenously, adenosine causes transient heart block in the atrioventricular (AV) node. This is ... This includes any re-entrant arrhythmias that require the AV node for the re-entry, e.g., AV reentrant tachycardia (AVRT) and ... Because of the effects of adenosine on AV node-dependent SVTs, adenosine is considered a class V antiarrhythmic agent. When ... and do not involve the AV node as part of the re-entrant circuit, are not typically converted by adenosine. However, the ...
Wolff-Parkinson-White syndrome
From there, the electrical stimulus is transmitted via internodal pathways to the atrioventricular (AV) node. After a brief ... Problems arise when this pathway creates an electrical circuit that bypasses the AV node. The AV node is capable of slowing the ... electrical activity that is initiated in the SA node travels through the accessory pathway, as well as through the AV node to ... AV node blockers should be avoided in atrial fibrillation and atrial flutter with WPW or history of it; this includes adenosine ...
Das Reizleitungssystem des Säugetierherzens
... "atrioventricular connecting system". The atrioventricular connecting system starts in the atrioventricular node, moves into the ... The monograph revealed the existence of the atrioventricular node and the function of Purkinje cells. It was used by Arthur ... Encouraged by their initial success and inspired by Tawara's discovery of the atrioventricular node, Keith and Flack extended ... Silverman, M. E.; Hollman, A. (1 October 2007). "Discovery of the sinus node by Keith and Flack: on the centennial of their ...
AV nodal reentrant tachycardia
AVNRT occurs when a reentrant circuit forms within or just next to the atrioventricular node. The circuit usually involves two ... The fundamental mechanism of AVNRT is a presence of a dual atrioventricular node physiology (present in half of the population ... which acts as a re-entrant circuit within the atrioventricular node. This can take several forms. "Typical", "common", or "slow ... These pathways are formed from tissue that behaves very much like the AV node, and some authors regard them as part of the AV ...
Premature atrial contraction
... node and propagating to the atrioventricular (AV) node, the signal is conducted both to the ventricle and back to the SA node ... However, if the atrial beat is premature enough, it may reach the atrioventricular node during its refractory period, in which ... This can be either a premature atrial contraction or a premature impulse from the atrioventricular node. SVES should be viewed ... Typically, the atrial impulse propagates normally through the atrioventricular node and into the cardiac ventricles, resulting ...
Vagus nerve
When hyperstimulated, the left vagal branch predisposes the heart to conduction block at the atrioventricular node. At this ... The right vagus branch innervates the sinoatrial node. In healthy people, parasympathetic tone from these sources is well- ...
Atrioventricular block
The signal travels from the SA node to the ventricles through the atrioventricular node (AV node). In an AV block, this ... Normally, the sinoatrial node (SA node) produces an electrical signal to control the heart rate. ... The electrical signal then travels to the AV node located on the lower portion of the interatrial septum. At the AV node there ... Atrioventricular block (AV block) is a type of heart block that occurs when the electrical signal traveling from the atria, or ...
Bundle of His
Atrioventricular node Bachmann's bundle Bundle branches Bundle of Kent Purkinje Fibers Sinoatrial node Logan, Carolynn M.; Rice ... As part of the electrical conduction system of the heart, it transmits the electrical impulses from the atrioventricular node ( ... as it transmits impulses from the atrioventricular node, located at the anterior-inferior end of the interatrial septum, to the ... Kistin AD (May 1949). "Observations on the anatomy of the atrioventricular bundle (bundle of His) and the question of other ...
List of ICD-9 codes 390-459: diseases of the circulatory system
... third degree 426.11 Atrioventricular block, first degree 426.12 Atrioventricular block, Mobitz II 426.13 Atrioventricular block ... Acute febrile mucocutaneous lymph node syndrome 446.5 Giant Cell arteritis(Temporal Arteritis) 447 Other disorders of arteries ... right 426.6 Sinoatrial heart block 426.7 Atrioventricular excitation, anomalous Wolff-Parkinson-White syndrome 427 Cardiac ... other diseases classified elsewhere 425.9 Secondary cardiomyopathy unspecified 426 Conduction disorders 426.0 Atrioventricular ...
Management of atrial fibrillation
... the atrioventricular node - which regulates heart rate, and to implant a pacemaker instead. This "ablate and pace" technique ... Rate control is achieved with medications that work by increasing the degree of block at the level of the AV node, effectively ... amiodarone has some AV node blocking effects (particularly when administered intravenously), and can be used in individuals ...
Cardiac pacemaker
Impulses from the sinus node reach the atrioventricular node which acts as the secondary pacemaker. The cells of the AV node ... This center is typically represented by cells inside the atrioventricular node (AV node), which is an area between the atria ... The sinoatrial node (SA node) is the primary pacemaker of the heart. It is a region of cardiac muscle on the wall of the upper ... If the SA node does not function, or the impulse generated in the SA node is blocked before it travels down the electrical ...
C1orf112
In-situ hybridization of the human transcriptome indicates expression is highest in the atrioventricular node, followed by the ... Although tissue-level expression is ubiquitous, C1orf112 is expressed highest in the testes, lymph nodes, brain marrow, and ...
Bachmann's bundle
... which run from the sinoatrial node to the atrioventricular node, converging in the region near the coronary sinus. Atrial ... James, Thomas N. (1 October 1963). "The connecting pathways between the sinus node and A-V node and between the right and the ... The normal cardiac rhythm originates in the sinoatrial node, which is located in the right atrium near the superior vena cava. ... Because it originates close to the sinoatrial node and consists of long parallel fibers, Bachmann's bundle is, during sinus ...
Tachycardia
AVRT may involve orthodromic conduction (where the impulse travels down the AV node to the ventricles and back up to the atria ... Adrenergic storm Anaemia Anxiety Atrial fibrillation Atrial flutter Atrial tachycardia Atrioventricular reentrant tachycardia ... is a rare but benign type of cardiac arrhythmia that may be caused by a structural abnormality in the sinus node. It can occur ... node, near the base of the superior vena cava Atrial fibrillation Atrial flutter AV nodal reentrant tachycardia Accessory ...
Heart valve
The atrioventricular valves are the mitral valve, and the tricuspid valve, which are situated between the atria and the ... Osler nodes and Roth spots. A particularly feared complication of valvular disease is the creation of emboli because of ... The valves of the human heart can be grouped in two sets: Two atrioventricular valves to prevent backflow of blood from the ... These valves do not have chordae tendineae, and are more similar to the valves in veins than they are to the atrioventricular ...
Syncope (medicine)
... is usually caused by sinoatrial node dysfunction or block or atrioventricular block. Blockages in major vessels or within the ... Sick sinus syndrome, a sinus node dysfunction, causing alternating bradycardia and tachycardia. Often there is a long pause ( ...
Complication (medicine)
... node. In the pathogenesis of atrial fibrillation, there is no effective pumping of blood into either the pulmonary or systemic ... of arrhythmia characterized by rapid and irregular heart rhythms due to irregular atrial activation by the atrioventricular (AV ... swollen lymph nodes underneath the chin and around the neck area). Streptococcal pharyngitis can lead to various complications ...
Junctional escape beat
It occurs when the rate of depolarization of the sinoatrial node falls below the rate of the atrioventricular node. This ... It is a protective mechanism for the heart, to compensate for the SA node no longer handling the pacemaking activity, and is ... dysrhythmia also may occur when the electrical impulses from the SA node fail to reach the AV node because of SA or AV block. ... A junctional escape complex is a normal response that may result from excessive vagal tone on the SA node (e.g. digoxin ...
AH-1058
... and conductance through the atrioventricular node. In addition AH-1058 has been shown to decrease systolic blood pressure while ... atrioventricular conduction > sinoatrial automaticity (level of sinoatrial self-activation). Takahara A, Uneyama H, Sasaki N, ... "On the ionic mechanism of cyproheptadine-induced bradycardia in a rabbit sinoatrial node preparation". European Journal of ...
Index of anatomy articles
... muscle astereognosis asterion asterixis astrocyte asynergy ataxia atlanto-occipital joint atlas atresia atrioventricular node ... short ciliary nerves shoulder shoulder blade shin sight sigmoid colon sigmoid sinus Simian crease simian shelf sinoatrial node ... hypothalmotegmental axon hypothenar muscles ileal vessels ileocecal valve ileocolic artery ileum iliac crest iliac lymph nodes ... enlargement lumbar spine lumbar vertebrae lumbosacral enlargement lumbosacral plexus lumbrical lunate lung lymph lymph nodes ...
Third-degree atrioventricular block
... is a medical condition in which the electrical impulse generated in the sinoatrial node (SA node) in the atrium of the heart ... This type of device typically listens for a pulse from the SA node via lead in the right atrium and sends a pulse via a lead to ... Early treatment of atrioventricular blockade is based on the presence and severity of symptoms and signs associated with ... Atropine works by reducing vagal stimulation through the AV node but will not be effective in those who have had a previous ...
Reflex bradycardia
... reduce the contractile forces of the atrial cardiac muscle and reduce the conduction velocity of the atrioventricular node (AV ... The M2 muscarinic receptors decrease the heart rate by inhibiting depolarization of the sinoatrial node via Gi protein-coupled ... node). However, M2 receptors have no effect on the contractile forces of the ventricular muscle. Stimuli causing reflex ...
Sinoatrial arrest
... not sinus node (normal P morphology is lost). Junctional escape (rate 40-60): originates near the AV node; a normal P wave is ... such as the atrio-ventricular junction or the ventricles, begins pacing and restores the heart action. This condition can be ... If a pacemaker other than the sinoatrial node is pacing the heart, this condition is known as an escape rhythm. If no other ... Sinoatrial arrest is a medical condition wherein the sinoatrial node of the heart transiently ceases to generate the electrical ...
Atrial fibrillation
Fibrosis is not limited to the muscle mass of the atria and may occur in the sinus node (SA node) and atrioventricular node (AV ... A heartbeat results when an electrical impulse from the atria passes through the atrioventricular (AV) node to the ventricles ... These disorganized waves conduct intermittently through the atrioventricular node, leading to irregular activation of the ... Rate control is achieved with medications that work by increasing the degree of the block at the level of the AV node, ...
Muscle fascicle
In the heart specialized cardiac muscle cells transmit electrical impulses from the atrioventricular node (AV node) to the ... These start as a single fascicle of fibers at the AV node called the bundle of His that then splits into three bundle branches ...
Pre-excitation syndrome
Physiologically, the normal electrical depolarization wave is delayed at the atrioventricular node to allow the atria to ... "atrioventricular node". In all pre-excitation syndromes, at least one more conductive pathway is present. ... so the electrical stimulus passes to the ventricle by this tract faster than via normal atrioventricular/bundle of His system, ...
Heart development
Pacemaker cells develop in the primitive atrium and the sinus venosus to form the sinoatrial node and the atrioventricular node ... At the end of the fourth week, two atrioventricular endocardial cushions appear. Initially the atrioventricular canal gives ... the superior endocardial cushions begin to form a pacemaker also known as the atrioventricular node. With the development of ... The two ends of the septum extend into the interior of the endocardial cushions in the atrioventricular canal. The opening ...
Automatic tachycardia
Junctional ectopic tachycardia, in which the focus is in the atrioventricular node (AVN), and Accelerated idioventricular ... since the sinoatrial node (SAN) is discharging at an abnormally fast rate. Atrial ectopic tachycardia, in which the focus or ...
Re-entry ventricular arrhythmia
Circus movement may also occur on a smaller scale within the AV node (dual AV nodal physiology), a large bypass tract is not ... Supraventricular Tachycardia: Atrioventricular Nodal Reentry and Wolff-Parkinson-White Syndrome. Goodman & Gilman's The ... WPW syndrome is an atrioventricular re-entrant tachycardia (AVRT), secondary to an accessory pathway that connects the ...
Neonatal lupus erythematosus
Disruption to action potential propagation can affect the AV and SA nodes which are part of the conduction system of the heart ... Sauer WH (3 June 2021). Link MS, Yeon SB (eds.). "Etiology of Atrioventricular block". UpToDate. Retrieved March 10, 2022. ...
CCDC130
... atrioventricular node, appendix, skeletal muscle, cardiac myocytes, tongue, and salivary gland. PB-CD8+ T cells had the highest ... lymph node, lung, thymus, thyroid, leukemia chronic myelogenous K562, and leukemia lymphoblastic molt4 samples all had at ...
Walter Koch (physician)
... and of Tawara's node, the atrioventricular node which is the beginning of the auriculo‐ventricular bundle (sometimes called the ... Koch became known for his work on the motor centres of the human heart, and coined the term "sinus node". Atrium (heart) ... atrio-ventricular bundle). Educated in Freiburg im Breisgau and at the Kaiser Wilhelm Academy in Berlin, he obtained his ...
Familial amyloid cardiomyopathy
Cardiac involvement is often identified with the presence of conduction system disease (sinus node or atrioventricular node ...
Atrioventricular
Left atrioventricular opening Atrioventricular fistula Atrioventricular node Atrioventricular valves, the mitral valve and ... Atrioventricular (having to do with an atrium and ventricle) can refer to: ... tricuspid valve This disambiguation page lists articles associated with the title Atrioventricular. If an internal link led you ...
Primary mesothelioma of atrioventricular node: cause of sudden death. | Journal of Clinical Pathology
ESC 365 - Leadless pacemaker implant with concomitant atrioventricular node ablation: experience in a single center study with...
Atrioventricular Node Reentry Supraventricular Tachycardia Treatment & Management: Medical Care, Surgical Care
... is a form of re-entrant rhythm within the region of the atrioventricular (AV) node. Re-entrant rhythms account for most ... Atrioventricular Node Reentry Supraventricular Tachycardia * Sections Atrioventricular Node Reentry Supraventricular ... Atrioventricular Node Reentry Supraventricular Tachycardia. Low voltage bridge in atrioventricular node reentry tachycardia ( ... Atrioventricular Node Reentry Supraventricular Tachycardia. Low voltage bridge in atrioventricular node reentry tachycardia ( ...
Expression of Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial and atrioventricular nodes...
Expression of Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial and atrioventricular nodes ... Expression of Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial and atrioventricular nodes ... Expression of Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial and atrioventricular nodes ... Expression of Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial and atrioventricular nodes ...
Heart Anatomy: Overview, Cardiac Chambers, Great Vessels and Septi
Atrioventricular node. The AV node is situated directly on the right atrial side of the central fibrous body in the muscular ... Sinus node. The sinoatrial (SA) node occupies a 1-cm2 area on the lateral surface of the junction of the superior vena cava and ... Atrioventricular septum. The atrioventricular (AV) septum, located behind the right atrium and left ventricle, is divided into ... Measuring approximately 0.1 cm x 0.3 cm x 0.6 cm, the node is flat and oval. The nodes left surface is juxtaposed to the ...
Lipedema: A Not-Uncommon Disease Still Goes Unrecognized
Atrial Fibrillation Causes, Symptoms, Types & Treatment
Outcomes after atrioventricular node ablation and biventricular pacing in patients with refractory atrial fibrillation and...
Frontiers | Heart Rhythm Insights Into Structural Remodeling in Atrial Tissue: Timed Automata Approach
2008). Computer three-dimensional reconstruction of the atrioventricular node. Circul. Res. 102, 975-985. doi: 10.1161/ ... A simple model of the right atrium of the human heart with the sinoatrial and atrioventricular nodes included. J. Clin. Monit. ... and the atrioventricular node (AVN)-which collects excitations wandering on the atria, and then uniformly transmits them ... Three-dimensional computer model of the right atrium including the sinoatrial and atrioventricular nodes predicts classical ...
Heart Rhythm Center | Samaritan Health Services
Wolff-Parkinson-White syndrome: MedlinePlus Genetics
A specialized cluster of cells called the atrioventricular node conducts electrical impulses from the hearts upper chambers ( ... that allows electrical signals to bypass the atrioventricular node and move from the atria to the ventricles faster than usual ... the atria) to the lower chambers (the ventricles). Impulses move through the atrioventricular node during each heartbeat, ...
Curriculum
Atrial Flutter Treatment & Management: Approach Considerations, Ventricular Rate Control, Electrical Cardioversion
... node conduction block. In the most common form of atrial flutter (type I atrial flutter), electrocardiography (ECG) ... Ventricular rate control can be achieved with drugs that block the atrioventricular (AV) node. Intravenous calcium channel ... Preferred medications that slow atrioventricular (AV) node conduction include beta blockers (eg, atenolol, metoprolol, ... because agents that act exclusively at the level of the AV node may enhance accessory pathway conduction. ...
Heart and Circulatory System (for Teens) - East Tenneesee Children's
Then the impulses travel down to the atrioventricular (or AV) node, which acts as a kind of relay station. From here, the ... During systole, the atrioventricular valves close, creating the first sound (the lub) of a heartbeat. When the atrioventricular ... This node is called the pacemaker of the heart because it sets the rate of the heartbeat and causes the rest of the heart to ... The sinus (or sinoatrial) node is a small area of tissue in the wall of the right atrium. It sends out an electrical signal to ...
Quick Facts: Overview of Abnormal Heart Rhythms - MSD Manual Consumer Version
How the list was created
Heart Rhythm Society advises against ablating atrioventricular node in atrial fibrillation patients when symptoms and heart ... Getting Started Lists of Recommendations Search Recommendations Cardiology HRS - Atrioventricular node ablation in patients ... Dont ablate the atrioventricular node in patients with atrial fibrillation when both symptoms and heart rate are acceptable ... Atrioventricular node ablation and pacemaker implantation may provide benefit in some patients when rate and related symptoms ...
Metoprolol Tartrate Tablets, USP
8026501/0518
Rx only
Brevibloc (esmolol) dosing, indications, interactions, adverse effects, and more
Additive sympatholytic action may worsen sinus node dysfunction and atrioventricular (AV) block.. esmolol, clonidine. Mechanism ... Additive sympatholytic action may worsen sinus node dysfunction and atrioventricular (AV) block. ... for bradycardia and atrioventricular block. To identify underlying risk factors of bradycardia and AV block, obtain a new or ... for bradycardia and atrioventricular block. To identify underlying risk factors of bradycardia and AV block, obtain a new or ...
What Is An EKG, and How Does It Work In The New Apple Watch?
The muscles surrounding these two chambers are triggered by two nodes: the sinoatrial (SA) node and the atrioventricular (AV) ... The AV node acts as a delay circuit, pausing until the ventricle is full. Then it depolarizes and the ventricle contracts, ... The SA node is the bodys natural pacemaker. This nerve cluster depolarizes and emits an electrical charge, starting the ... The dip at Q is the AV node depolarizing. This seems small in comparison to the R wave, as the nerve impulse passes through the ...
Arrhythmia - Wikipedia
SA node). The impulse initially causes both atria to contract, then activates the atrioventricular node (AV node), which is ... These are also known as AV blocks, because the vast majority of them arise from pathology at the atrioventricular node. They ... Rhythms produced by an ectopic focus in the atria, or by the atrioventricular node, are the least dangerous dysrhythmias; but ... These cells are found in the conduction system of the heart and include the SA node, AV node, Bundle of His, and Purkinje ...
Alexandre Janin | IntechOpen
Pacemakers and ICDs | Life
SA Node). The impulse generated at the SA Node causes the atria to contract. It then passes to the "sub-station", the atrio- ... The SA Node is sensitive to changes in the body - heat (such as a fever), exercise or stimulant drugs will cause it to "fire" ... The SA node and all the components of the conduction system may also be affected by degenerative changes and diseases, which ... Used in the atrium, it may be effective if the sino-atrial node malfunctions, but the rest of the conduction system is intact ...
Atrial flutter
Impulses from the atria are conducted to the ventricles through the atrio-ventricular node. Due primarily to its longer ... and lymph nodes. Thrombosis/Phlebitis/Thrombophlebitis (Deep vein thrombosis, May-Thurner syndrome, Portal vein thrombosis, ... Bypassing the AV node, the atrial rate of 300 beats/minute leads to a ventricular rate of 300 beats/minute (1:1 conduction). ... the accessory pathway may conduct activity from the atria to the ventricles at a rate that the AV node would usually block. ...
Heart - Simple English Wikipedia, the free encyclopedia
This motion is called atrial systole. Once electrical impulse goes through the atrio-ventricular node (AV Node). The AV Node ... The electricity starts in the sino-atrial node (acronym SA Node) The SA Node is a group of cells called pacemaker cells in the ... The order is: Sino-Atrial Node → Atria (systole) → Atrio-Ventricular Node → Bundle of His → Bundle branches → Purkinje Fibers ... After the electrical impulse goes through the AV Node, the electrical impulse will go through the conduction system of the ...
A return to rhythm? PVI proves superior in low EF CHF - Heart
Atrio-ventricular node ablation has been used to treat symptomatic atrial fibrillation with poor rate control although these ... Biventricular pacing has recently been shown to be superior to right ventricular pacing following atrio-ventricular node ... AV node ablation and biventricular pacing). 100% of patients in the AV node ablation and pacing arm had atrial fibrillation at ... trial aimed to compare pulmonary vein isolation with atrioventricular node ablation and biventricular pacing in patients with ...
WikiGenes - Atrial Fibrillation
Long-term follow-up after radiofrequency modification of the atrioventricular node in patients with atrial fibrillation. Morady ... Frequency-dependent effects of diltiazem on the atrioventricular node during experimental atrial fibrillation. Talajic, M., ... Frequency-dependent effects of diltiazem on the atrioventricular node during experimental atrial fibrillation [25]. ... Enhanced atrioventricular conduction atrial fibrillation after lidocaine administration. Sinatra, S.T., Jeresaty, R.M. JAMA ( ...
Available Resources | Skyscape
Sinoatrial NodeAtrialTachycardiaAtrio-ventricularPacemakerSinus node dysfunctionVentriclesAblation and biventricularImpulsesBundleConduction systemNodalRhythmsAVNRTValvesMetoprololIntermittentChambersLymphHeartElectricalImpulsePathwaysAnatomyInferiorlyHeartbeatCommonlyTypicallyPulmonaryPrimaryCellsSymptomsRatePatientsActs
Sinoatrial Node10
- In this study, we have investigated the expression (at protein and mRNA levels) of GFP-tagged Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial node (SAN), atrioventricular node (AVN), His bundle and working myocardium of transgenic mice. (wustl.edu)
- Two clusters of specific and specially organized cells: the sinoatrial node (SAN)-the thin and elongated piece of cardiac tissue built of self-exciting cells, and the atrioventricular node (AVN)-which collects excitations wandering on the atria, and then uniformly transmits them downwards to cause the contraction of ventricles, are crucial elements for the electrophysiology of the heart. (frontiersin.org)
- The sinus (or sinoatrial) node is a small area of tissue in the wall of the right atrium. (kidshealth.org)
- There are special pacemaker cells in a part of your heart called the SA node (sinoatrial node). (msdmanuals.com)
- The signal begins in the sinoatrial node, or SA node, located in the right atrium. (merckmanuals.com)
- And this starts in the region known as the pacemaker, or the sinoatrial node, that is located in the right atrium. (futurelearn.com)
- The electrical activity begins in the sinoatrial node, then spreads across the rest of the atrium, through to the other atrium, and then down into the ventricles. (futurelearn.com)
- Each beat of your heart begins with an electrical signal from the sinoatrial node, called SA node. (smartdraw.com)
- The electrical activity of the heart originates in a tissue located in the right atrium called the sinoatrial node, which is the innate pacemaker. (rigging.top)
- The electrical signal from the sinoatrial node is first transmitted to the entire atrium, and then, through a tissue called the atrioventricular node, it is divided into left and right branches and transmitted to the entire ventricle, thereby causing the heart to repeatedly beat rhythmically. (rigging.top)
Atrial14
- Don't ablate the atrioventricular node in patients with atrial fibrillation when both symptoms and heart rate are acceptable controlled by well-tolerated medical therapy. (choosingwisely.org)
- The regular synchronised contraction of all four chambers of the heart is regulated by electrical impulses generated within a group of specialised cells in the heart, called the sino-atrial node (SA Node). (news24.com)
- Used in the atrium, it may be effective if the sino-atrial node malfunctions, but the rest of the conduction system is intact and can be used to conduct impulses from the pacemaker. (news24.com)
- Due primarily to its longer refractory period, the AV node exerts a protective effect on heart rate by blocking atrial impulses in excess of about 180 beats/minute (This block is dependent on the age of the patient, and can be calculated roughly by subtracting patient age from 220). (bionity.com)
- The electricity starts in the sino-atrial node ( acronym SA Node) The SA Node is a group of cells called pacemaker cells in the right atria. (wikipedia.org)
- Atrio-ventricular node ablation has been used to treat symptomatic atrial fibrillation with poor rate control although these studies have contained few subjects with low ejection fractions. (bmj.com)
- 100% of patients in the AV node ablation and pacing arm had atrial fibrillation at 3 and 6 months - an unexpected finding. (bmj.com)
- Paroxysmal supraventricular tachycardia (pSVT) is an umbrella term that can refer to one of several pathologies, such as atrioventricular node re-entrant tachycardia and less commonly atrioventricular reciprocating tachycardia, as well as several other less common atrial tachycardias. (emra.org)
- These drugs can block the AV node and promote rapid 1:1 conduction from the atrium to the ventricle during atrial fibrillation and thus induce ventricular fibrillation. (acpinternist.org)
- The diagnosis of critical pathological rhythms, including atrial fibrillation and high-grade atrioventricular node block, was not missed by the Nabz Hooshmand-1 and GE MAC 1200 ECG devices. (lww.com)
- Other arrhythmias arising outside of the SA node may occur, and among the most serious of these is atrial fibrillation. (petplace.com)
- Reduced renal function, higher doses, bradycardia, history of sustained VT/VF, and atrial fibrillation with sinus node dysfunction can also increase the risk of TdP. (pdr.net)
- The signal from the SA node is delayed at the AV (slow conduction) to allow atrial systole to precede ventricular systole. (wordpress.com)
- After excitation reaches the AV node and atrial systole has ended, it spreads rapidly down the ventricles via specialised cells that form the Bundle of His (of which there is a left and a right bundle) and to the rest of the myocardium via similar Purkinje fibres. (wordpress.com)
Tachycardia8
- Atrioventricular node reentrant tachycardia (AVNRT) is a form of reentrant rhythm within the region of the atrioventricular (AV) node. (medscape.com)
- Nonsustained atrioventricular node reentry tachycardia (AVNRT). (medscape.com)
- it is not synonymous with AV node reentrant tachycardia (AVNRT) because the incidental finding of dual AV nodal physiology does not predict AVNRT in children and adolescents after successful accessory pathway ablation. (medscape.com)
- Emergency treatment of patients with hemodynamic instability in the setting of atrioventricular node reentrant tachycardia (AVNRT) is directed at converting the rhythm to sinus through a brief episode of AV block. (medscape.com)
- Ablation of atrioventricular node reentrant tachycardia (AVNRT) is accomplished by delivering either radiofrequency or cryothermal energy over the slow pathway. (medscape.com)
- Atrioventricular node ablation and pacemaker implantation may provide benefit in some patients when rate and related symptoms cannot be controlled by medication therapy,(Class IIa, indicated) or when there is concern for possible tachycardia-induced cardiomyopathy (Class IIb, may be considered). (choosingwisely.org)
- It also can result from tachyarrhythmias (eg, ventricular tachycardia, torsade de pointes, supraventricular tachycardia) or bradyarrhythmias (eg, sinus node disease, second- or third-degree heart block, drug-induced bradycardia). (psychiatrictimes.com)
- Noheria, A , Asirvatham, SJ & McLeod, CJ 2016, ' Unusual Atrioventricular Reentry Tachycardia in Congenitally Corrected Transposition of Great Arteries: A Novel Site for Catheter Ablation ', Circulation: Arrhythmia and Electrophysiology , vol. 9, no. 6, e004120. (elsevier.com)
Atrio-ventricular6
- It then passes to the "sub-station", the atrio-ventricular node, which carries it into the conduction system of the ventricles. (news24.com)
- Impulses from the atria are conducted to the ventricles through the atrio-ventricular node. (bionity.com)
- Once electrical impulse goes through the atrio-ventricular node (AV Node). (wikipedia.org)
- Biventricular pacing has recently been shown to be superior to right ventricular pacing following atrio-ventricular node ablation. (bmj.com)
- It is called the atrio-ventricular node (AV node). (chrichmond.org)
- The atrio-ventricular node is located at the base of the right atrium, just above the junction of the atria and ventricles. (wordpress.com)
Pacemaker6
- This node is called the pacemaker of the heart because it sets the rate of the heartbeat and causes the rest of the heart to contract in its rhythm. (kidshealth.org)
- The SA node is the body's natural pacemaker. (howtogeek.com)
- The pacemaker or sinoatrial (SA) node generates an impulse that is spread throughout the atria, causing those two chambers to contract, sending blood into the ventricles. (gradesaver.com)
- Normal heart rhythm is initiated by the sinus node, which serves as the heart's internal pacemaker. (healthonecares.com)
- The pacemaker activity of the AV node produces a slower firing rate (around 40-60/min compared with the SA node's 70-80/min). (wordpress.com)
- 8. Intermittent or persistent 2nd or 3rd degree atrioventricular block, sinus node dysfunction with clinically significant bradycardia or sinus pauses, not treated with a pacemaker. (who.int)
Sinus node dysfunction1
- [3] [7] Bradyarrhythmias are due to sinus node dysfunction or atrioventricular conduction disturbances . (wikipedia.org)
Ventricles18
- During AVNRT, the circuit typically involves both a fast and a slow pathway within the region of the AV node, which allows the impulses to proceed down the His-Purkinje system to the ventricles while simultaneously proceeding in a retrograde fashion to depolarize the atria and reenter the node. (medscape.com)
- A specialized cluster of cells called the atrioventricular node conducts electrical impulses from the heart's upper chambers (the atria) to the lower chambers (the ventricles). (medlineplus.gov)
- Impulses move through the atrioventricular node during each heartbeat, stimulating the ventricles to contract slightly later than the atria. (medlineplus.gov)
- People with Wolff-Parkinson-White syndrome are born with an extra connection in the heart, called an accessory pathway, that allows electrical signals to bypass the atrioventricular node and move from the atria to the ventricles faster than usual. (medlineplus.gov)
- The AV node controls how signals pass from the upper chambers of your heart (atria) to the lower chambers (ventricles). (msdmanuals.com)
- The SA node triggers the atria to contract, pushing blood into the ventricles. (merckmanuals.com)
- The electrical signal then travels through the atrioventricular node, or AV node, and into the ventricles. (merckmanuals.com)
- This means that electrical activity can only pass from the atria to the ventricles through a small region called the atrioventricular node. (futurelearn.com)
- As the electrical activity passes through the node and into the rest of the ventricles, there is depolarisation of the ventricles which causes them to contract. (futurelearn.com)
- The AV node is an electrical gatekeeper between the atrium and ventricle that helps to time the way blood flows into the ventricles. (barnesjewish.org)
- The signal then travels through the atria to the atrioventricular (AV) node and into the ventricles, causing them to contract and pump blood. (stelizabeth.com)
- The signal arrives at the AV node near the ventricles, where it slows for an instant to allow your heart's right and left ventricles to fill with blood. (smartdraw.com)
- The impulse then travels across the upper chambers of the heart (atria), to an intermediate station (atrioventricular [AV] node), and finally to the lower chambers of the heart (ventricles). (petplace.com)
- This electrical signal is transmitted to the ventricles by the atrioventricular node, allowing for a coordinated impulse between the right and left sides of the heart. (healthonecares.com)
- It often involves having an extra electrical wire (in addition to the AV node) between the atria and ventricles that causes electrical impulses to circle (reenter) between the upper and lower chambers causing an abnormally fast heart rate. (chrichmond.org)
- There is a small delay at the AV node, which allows the atria to complete contracting before the ventricles are depolarized. (thegatheringbaltimore.com)
- The latter directs this excitation towards the atrioventricular node, which (because there is a layer of fibrous, non-conducting tissue between ventricles and atria) is the only point of electrical communication between the atria and ventricles. (wordpress.com)
- The AV node is the ONLY point of contact between atria and ventricles i.e. in order from SA activity to reach the ventricles, it must go through the AV node. (wordpress.com)
Ablation and biventricular2
- In the AV node ablation and biventricular pacing arm, lead displacement occurred in 1 patient and 1 had a pneumothorax. (bmj.com)
- PVI ( arguably a form of rhythm control) in this trial had a good success rate and resulted in superior morphological and functional outcomes when compared to the optimal rate control strategy (AV node ablation and biventricular pacing). (bmj.com)
Impulses2
- Then the impulses travel down to the atrioventricular (or AV) node , which acts as a kind of relay station. (kidshealth.org)
- Sick sinus syndrome can be caused by scarring near the sinus node that's slowing, disrupting or blocking the travel of impulses. (stelizabeth.com)
Bundle1
- It gives rise to the atrioventricular bundle of the conduction system of the heart. (bvsalud.org)
Conduction system2
- The conduction system includes a gateway called the AV node (atrioventricular node). (msdmanuals.com)
- The SA node and all the components of the conduction system may also be affected by degenerative changes and diseases, which can affect only certain parts, or all of the system. (news24.com)
Nodal1
- typically, atrioventricular [AV] nodal-conduction blocking medications are avoided in the acute setting of WPW), or AV nodal blocking medications to slow AV nodal conduction). (medscape.com)
Rhythms2
- Normal heart rhythms begin in the sinus node, which is located in the right upper chamber of the heart. (petplace.com)
- A WPW pathway bypasses the AV node and can transmit electrical signals through the heart faster than through the AV node This can cause SVT or other abnormal heart rhythms. (chrichmond.org)
AVNRT1
- [ 3 ] Multiple atypical AVNRT circuits using rightward and leftward inferior extensions of the AV node have been described. (medscape.com)
Valves2
- Now, in some cases, a small U-wave is also visible, and this is due to repolarisation of the papillary muscles that are associated with the atrioventricular valves. (futurelearn.com)
- The atrioventricular valves close, and then the semilunar valves open. (thegatheringbaltimore.com)
Metoprolol1
- Preferred medications that slow atrioventricular (AV) node conduction include beta blockers (eg, atenolol, metoprolol, propranolol) and calcium channel blockers (eg, verapamil, diltiazem). (medscape.com)
Intermittent1
- Cardiac involvement associated with Lyme disease includes intermittent atrioventricular heart block, often involving the atrioventricular node (although heart block can occur at multiple levels), and sometimes myopericarditis. (cfp.ca)
Chambers1
- The muscles surrounding these two chambers are triggered by two nodes: the sinoatrial ( SA) node and the atrioventricular (AV) node. (howtogeek.com)
Lymph2
- Enlarged including sinus bradycardia and grade of C. ulcerans -infected pigs may lead cervical lymph nodes were palpable I atrioventricular block, were present. (cdc.gov)
- Sinusoidal Pattern Expanded subcapsular, cortical, and medullary sinuses are sometimes seen in lymph nodes draining limbs, stomach organs, varied infammatory lesions, and malignancies. (castellodelleregine.it)
Heart5
- The EKG is an electrical meter and recording device that can see the electrical signals generated by the SA and AV nodes in the heart. (howtogeek.com)
- Because the Apple Watch only has one lead, it can't diagnose heart attacks due to an inadequate blood supply, structural defects, or other conditions that may involve more subtle problems with the nerves and nodes in the heart. (howtogeek.com)
- In a typical heart rhythm, a tiny cluster of cells at the sinus node sends out an electrical signal. (stelizabeth.com)
- The sinus node is responsible for setting the pace of the heart. (stelizabeth.com)
- Each heartbeat originates as an electrical impulse in the upper right chamber of the heart (sinoatrial [SA] node). (petplace.com)
Electrical1
- The electrical impulse arrives at the atrioventricular node (AV node) shortly after the atria are depolarized. (thegatheringbaltimore.com)
Impulse2
- After the cycle is complete, the nodes repolarize , stopping the nerve impulse. (howtogeek.com)
- The impulse generated at the SA Node causes the atria to contract. (news24.com)
Pathways1
- Antiarrhythmic agents are reserved for second-line therapy, particularly in patients with accessory pathways located close to the atrioventricular (AV) node. (acpinternist.org)
Anatomy1
- Knowledge of the anatomy of the Koch triangle (ie, where the AV node is located) is needed to understand how slow pathway ablation is performed. (medscape.com)
Inferiorly1
- The slow pathway(s) approach the compact AV node from inferiorly and have a relatively longer conduction time and an ERP that typically is short when compared to the fast pathway ERP. (medscape.com)
Heartbeat1
- This is the start of your heartbeat, where the SA node is depolarizing. (howtogeek.com)
Commonly1
- Sick sinus syndrome is an abnormality that affects the SA node: It most commonly occurs in Miniature Schnauzers, Dachshunds, Cocker Spaniels, and West Highland White Terriers. (petplace.com)
Typically1
- While abnormalities of the sinus node are typically a consequence of a systemic disorder, such as hypo- or hyperthyroidism, primary sinus disease is common and can lead to an arrhythmia known as sick sinus syndrome. (petplace.com)
Pulmonary1
- The atrioventricular node then receives the signal, and after a short delay, initiates the contraction of the muscles in the ventricle, thus sending blood into the aorta and pulmonary artery. (gradesaver.com)
Primary1
- Primary mesothelioma of atrioventricular node: cause of sudden death. (bmj.com)
Cells1
- The AV node cells are unique in that they are smaller in diameter and thus have a smaller conduction velocity. (wordpress.com)
Symptoms2
- However, according to current professional society clinical guidelines, the risks of AV node ablation outweigh the benefits among patients with no symptoms and who have appropriate rate control with well-tolerated medical therapy. (choosingwisely.org)
- The symptoms are similar to V-tach, but SVT develops in the atria or the atrioventricular (AV) node. (barnesjewish.org)
Rate1
- The SA Node is sensitive to changes in the body - heat (such as a fever), exercise or stimulant drugs will cause it to "fire" more often, and speed up the pulse rate. (news24.com)
Patients1
- 41 patients underwent PVI and 40 AV node ablation with biventricular pacing. (bmj.com)
Acts1
- The AV node acts as a delay circuit, pausing until the ventricle is full. (howtogeek.com)