Atrial Function, Left: The hemodynamic and electrophysiological action of the LEFT ATRIUM.Atrial Function: The hemodynamic and electrophysiological action of the HEART ATRIA.Atrial Function, Right: The hemodynamic and electrophysiological action of the RIGHT ATRIUM.Heart Atria: The chambers of the heart, to which the BLOOD returns from the circulation.Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Echocardiography, Doppler, Pulsed: Echocardiography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.Electric Countershock: An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)Pericardiectomy: Surgical excision (total or partial) of a portion of the pericardium. Pericardiotomy refers to incision of the pericardium.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Heart Function Tests: Examinations used to diagnose and treat heart conditions.Echocardiography, Transesophageal: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Ventricular Function: The hemodynamic and electrophysiological action of the HEART VENTRICLES.Observer Variation: The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Ventricular Function, Right: The hemodynamic and electrophysiological action of the right HEART VENTRICLE.Human Rights: The rights of the individual to cultural, social, economic, and educational opportunities as provided by society, e.g., right to work, right to education, and right to social security.Ventricular Dysfunction, Right: A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.Echocardiography, Three-Dimensional: Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Hypothermia, Induced: Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Heart Septal Defects, Atrial: Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.Cognition: Intellectual or mental process whereby an organism obtains knowledge.Cognition Disorders: Disturbances in mental processes related to learning, thinking, reasoning, and judgment.Heart Arrest, Induced: A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).Physical Endurance: The time span between the beginning of physical activity by an individual and the termination because of exhaustion.Echocardiography, Doppler, Color: Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.Exercise: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.Cardiac Volume: The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Aortic Valve Prolapse: The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.Liver Function Tests: Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.Pleurodesis: The production of adhesions between the parietal and visceral pleura. The procedure is used in the treatment of bronchopleural fistulas, malignant pleural effusions, and pneumothorax and often involves instillation of chemicals or other agents into the pleural space causing, in effect, a pleuritis that seals the air leak. (From Fishman, Pulmonary Diseases, 2d ed, p2233 & Dorland, 27th ed)Pleural Effusion, Malignant: Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.Talc: Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed)Pericarditis, Constrictive: Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.Liver Diseases: Pathological processes of the LIVER.Cardiac Resynchronization Therapy: The restoration of the sequential order of contraction and relaxation of the HEART ATRIA and HEART VENTRICLES by atrio-biventricular pacing.Mitral Valve Insufficiency: Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.Cardiac Pacing, Artificial: Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.Atrial Natriuretic Factor: A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.Iron-Dextran Complex: A complex of ferric oxyhydroxide with dextrans of 5000 to 7000 daltons in a viscous solution containing 50 mg/ml of iron. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)Aldosterone: A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.Receptors, Atrial Natriuretic Factor: Cell surface proteins that bind ATRIAL NATRIURETIC FACTOR with high affinity and trigger intracellular changes influencing the behavior of cells. They contain intrinsic guanylyl cyclase activity.Renin: A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.Natriuretic Peptide, C-Type: A PEPTIDE of 22 amino acids, derived mainly from cells of VASCULAR ENDOTHELIUM. It is also found in the BRAIN, major endocrine glands, and other tissues. It shares structural homology with ATRIAL NATRIURETIC FACTOR. It has vasorelaxant activity thus is important in the regulation of vascular tone and blood flow. Several high molecular weight forms containing the 22 amino acids have been identified.

Regional differences in the recovery course of tachycardia-induced changes of atrial electrophysiological properties. (1/150)

BACKGROUND: Regional differences in recovery of tachycardia-induced changes of atrial electrophysiological properties have not been well studied. METHODS AND RESULTS: In the control group (5 dogs), atrial effective refractory period (AERP) and inducibility of atrial fibrillation (AF) were assessed before and every 4 hours for 48 hours after complete atrioventricular junction (AVJ) ablation with 8-week VVI pacing. In experimental group 1 (15 dogs), AERP and inducibility of AF were assessed before and after complete AVJ ablation with 8-week rapid right atrial (RA) pacing (780 bpm) and VVI pacing. In experimental group 2 (7 dogs), AERP and inducibility of AF were assessed before and after 8-week rapid left atrial (LA) pacing and VVI pacing. AERP and inducibility and duration of AF were obtained from 7 epicardial sites. In the control group, atrial electrophysiological properties obtained immediately and during 48-hour measurements after pacing did not show any change. In the 2 experimental groups, recovery of atrial electrophysiological properties included a progressive recovery of AERP shortening, recovery of AERP maladaptation, and decrease of duration and episodes of reinduced AF. However, recovery of shortening and maladaptation of AERP and inducibility of AF was slower at the LA than at the RA and Bachmann's bundle. CONCLUSIONS: The LA had a slower recovery of tachycardia-induced changes of atrial electrophysiological properties, and this might play a critical role in initiation of AF.  (+info)

Influence of right atrial pressure on the cardiac pacemaker response to vagal stimulation. (2/150)

We have recently shown that the intrinsic rate response to an increase in right atrial pressure is augmented when cardiac muscarinic receptors are activated. This present study examines the cardiac pacemaker response to vagal stimulation at different values of right atrial pressure in isolated rat right atrium and in the rabbit heart in situ. In the rat atrium, when pressure was raised in steps from 2 to 10 mmHg, there was a progressive reduction in the response to vagal stimulation [40.5 +/- 7.2% reduction (mean +/- SE) at 8 mmHg, P < 0.01], which was independent of the level of vagal bradycardia, that persisted in the presence of the beta-adrenergic agonist isoproterenol. In barbiturate-anesthetized rabbits with cervical vagi cut and beta-adrenergic blockade, raising right atrial pressure approximately 2.5 mmHg by blood volume expansion reduced the bradycardia elicited by electrical stimulation of the peripheral end of the right vagus nerve (9.1 +/- 1.1% reduction, P < 0.0001). These results demonstrate that vagal bradycardia is modulated by the level of right atrial pressure and suggest that normally right atrial pressure may interact with cardiac vagal activity in the control of heart rate.  (+info)

Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. (3/150)

Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined. An intraduodenal administration of SRBT (1 g/kg) prevented theophylline (5 mg/kg, i.v.)-induced tachycardia in rats. SRBT also attenuated an increase in arterial blood pressure with a slow reduction in heart rate of rats treated with theophylline, with no influence on the plasma level of theophylline. However, SRBT did not change the beating rate of right atrium isolated from rats in the absence or presence of theophylline or isoproterenol. The locomotor activity of theophylline in mice was reduced by the treatment with SRBT. Furthermore, the latency of convulsions in mice induced by administration of theophylline at a higher dose (240 mg/kg, i.p.) was prolonged by treatment with SRBT (1 g/kg, p.o.) and seven out of fifteen mice were saved from death due to convulsions. These results suggest that theophylline-induced tachycardia and central nervous stimulation are suppressed by SRBT and that SRBT may reduce the undesirable actions of theophylline on the cardiovascular and central nervous systems.  (+info)

Rate-dependent conduction block of the crista terminalis in patients with typical atrial flutter: influence on evaluation of cavotricuspid isthmus conduction block. (4/150)

BACKGROUND: The crista terminalis (CT) has been identified as the posterior boundary of typical atrial flutter (AFL) in the lateral wall (LW) of the right atrium (RA). To study conduction properties across the CT, rapid pacing was performed at both sides of the CT after bidirectional conduction block was achieved in the cavotricuspid isthmus by radiofrequency catheter ablation. METHODS AND RESULTS: In 22 patients (aged 61+/-7 years) with AFL (cycle length, 234+/-23 ms), CT was identified during AFL by double electrograms recorded between the LW and posterior wall (PW). After the ablation procedure, decremental pacing trains were delivered from 600 ms to 2-to-1 local capture at the LW and PW or coronary sinus ostium (CSO). At least 5 bipolar electrograms were recorded along the CT from the high to the low atrium next to the inferior vena cava. No double electrograms were recorded during sinus rhythm in that area. Complete transversal conduction block all along the CT (detected by the appearance of double electrograms at all recording sites and craniocaudal activation sequence on the side opposite to the pacing site) was observed in all patients during pacing from the PW or CSO (cycle length, 334+/-136 ms), but it was fixed in only 4 patients. During pacing from the LW, complete block appeared at a shorter pacing cycle length (281+/-125 ms; P<0.01) and was fixed in 2 patients. In 3 patients, complete block was not achieved. CONCLUSIONS: These data suggest the presence of rate-dependent transversal conduction block at the crista terminalis in patients with typical AFL. Block is usually observed at longer pacing cycle lengths with PW pacing than with LW pacing. This difference may be a critical determinant of the counterclockwise rotation of typical AFL.  (+info)

Free-floating thrombi in the right heart: diagnosis, management, and prognostic indexes in 38 consecutive patients. (5/150)

BACKGROUND: Floating right heart thrombi (FRHTS) are a rare phenomenon, encountered almost exclusively in patients with suspected or proven pulmonary embolism and diagnosed by transthoracic echocardiography. Their management remains controversial. METHODS AND RESULTS: We report on a series of 38 consecutive patients encountered over the past 12 years. Thirty-two patients were in NYHA class IV, 20 in cardiogenic shock. Echocardiography usually demonstrated signs of cor pulmonale: right ventricular overload (91.7% of the population), paradoxical interventricular septal motion (75%), and pulmonary hypertension (86. 1%). The thrombus was typically wormlike (36 of 38 patients). It extended from the left atrium through a patent foramen ovale in 4 patients. Pulmonary embolism was confirmed in all but 1. Mortality was high (17 of 38 patients) irrespective of the therapeutic option chosen: surgery (8 of 17), thrombolytics (2 of 9), heparin (5 of 8), or interventional percutaneous techniques (2 of 4). The in-hospital mortality rate was significantly linked with the occurrence of cardiac arrest. Conversely, the outcome after discharge was usually good, because 18 of 21 patients were still alive 47.2 months later (range, 1 to 70 months). CONCLUSIONS: Severe pulmonary embolism was the rule in our series of FRHTS (mortality rate, 44.7%). The choice of therapy had no effect on mortality. Emergency surgery is usually advocated. However, thrombolysis is a faster, readily available treatment and seems promising either as the only treatment or as a bridge to surgery. In patients with contraindications to surgery or lytic therapy, interventional techniques may be proposed.  (+info)

Short-term effect of atrial fibrillation on atrial contractile function in humans. (6/150)

BACKGROUND: Conversion of chronic atrial fibrillation (AF) is associated with atrial stunning, but the short-term effect of a brief episode of AF on left atrial appendage (LAA) emptying velocity is unknown. The purpose of this study was to determine whether a short episode of AF affects left atrial function and whether verapamil modifies this effect. METHODS AND RESULTS: The subjects of this study were 19 patients without structural heart disease undergoing an electrophysiology procedure. In 13 patients, LAA emptying velocity was measured by transesophageal echocardiography in the setting of pharmacological autonomic blockade before, during, and after a short episode of AF. During sinus rhythm, the baseline LAA emptying velocity was measured 5 times and averaged. AF was then induced by rapid right atrial pacing. After either spontaneous or electrical conversion, LAA emptying velocity was measured immediately on resumption of sinus rhythm and every minute thereafter. The mean duration of AF was 15.3+/-3.8 minutes. The mean baseline emptying velocity was 70+/-20 cm/s. The first post-AF emptying velocity was 63+/-20 cm/s (P=0.02 versus baseline emptying velocity). The post-AF emptying velocity returned to the baseline emptying velocity value after 3.0 minutes. The mean percent reduction in post-AF emptying velocity was 9.7+/-21% (range, 15% increase to 56% decrease). A second group of 6 patients were pretreated with verapamil (0.1-mg/kg IV bolus followed by an infusion of 0.005 mg. kg-1. min-1). In these patients, the first post-AF emptying velocity, 58+/-14 cm/s, was not significantly different from the pre-AF emptying velocity, 60+/-13 cm/s (P=0.08). CONCLUSIONS: In humans, several minutes of AF may be sufficient to induce atrial contractile dysfunction after cardioversion. When atrial contractile dysfunction occurs, there is recovery of AF within several minutes. AF-induced contractile dysfunction is attenuated by verapamil and may be at least partially mediated by cellular calcium overload.  (+info)

Functional studies in atrium overexpressing A1-adenosine receptors. (7/150)

1. Adenosine and the A1-adenosine receptor agonist R-PIA, exerted a negative inotropic effect in isolated, electrically driven left atria of wild-type mice. 2. In left atria of mice overexpressing the A1-adenosine receptor, adenosine and R-PIA exerted a positive inotropic effect. 3. The positive inotropic effect of adenosine and R-PIA in transgenic atria could be blocked by the A1-adenosine receptor antagonist DPCPX. 4. In the presence of isoprenaline, adenosine exerted a negative inotropic effect in wild-type atria but a positive inotropic effect in atria from A1-adenosine receptor overexpressing mice. 5. The rate of beating in right atria was lower in mice overexpressing A1-adenosine receptors compared with wild-type. 6. Adenosine exerted comparable negative chronotropic effects in right atria from both A1-adenosine receptor overexpressing and wild-type mice. 7. A1-adenosine receptor overexpression in the mouse heart can reverse the inotropic but not the chronotropic effects of adenosine, implying different receptor-effector coupling mechanisms.  (+info)

Calf blood flow during prolonged tilt in idiopathic dilated cardiomyopathy and after cardiac transplantation. (8/150)

In severe congestive heart failure (CHF), abnormal reflex control of calf blood flow during brief head-up tilt that appears to normalize after transplantation (HTX) may be present during prolonged observation also. Therefore, we studied the effect of prolonged (30 min) 50 degrees head-up tilt on calf skeletal muscle blood flow measured by the local (133)Xe washout method in CHF and after HTX and in patients with the presence vs. absence of native right atrium (+PNA and -PNA, respectively). During brief head-up tilt, skeletal muscle blood flow increased 13 +/- 42% in 9 severe CHF patients in contrast to a -28 +/- 22% decrease (P < 0.01) in 11 control subjects, -24 +/- 30% decrease in 15 moderate CHF patients (P < 0.05), -25 +/- 14% decrease in 12 patients with recent HTX (P < 0.01), and -21 +/- 24% decrease in 8 patients with distant HTX (P = 0.06). However, during sustained tilt, blood flow declined to similar levels of that in the other groups in severe CHF. HTX -PNA vs. +PNA showed blunted skeletal muscle vasomotor control (P < 0.05) and a higher systolic blood pressure (139 +/- 14 vs. 125 +/- 15 mmHg, P < 0.05) and heart rate (92 +/- 10 vs. 83 +/- 8 beats/min, P < 0.05). Thus paradox vasodilatation of calf skeletal muscle in severe CHF is present only during brief but not prolonged tilt. This may be one explanation of the rare presence of orthostatic intolerance in CHF and implies only a minor possible role for the abnormality in edema pathogenesis. Removal of all right atrium in HTX has an important hemodynamic impact that may possibly affect later clinical outcome.  (+info)

Defective conduit function of the oesophagus readily induces clinical symptoms and may have serious effects on nutrition and the lungs, the latter resulting from aspiration of gastro-oeophageal contents. Oesophageal pain and dysphagia caused by benign or malignant diseases of the muscular layer or epithelium are often disabling....
We evaluated the relationship between susceptibility to arrhythmias caused by right atrial (RA) enlargement and alterations in transmembrane potentials and ultrastructure. RA enlargement was produced in eight dogs (TI) by excising the septal cusp of the tricuspid valve through a right atriotomy and constricting the pulmonary artery. This procedure resulted in RA dilation and hypertrophy. Four sham-operated dogs (S) also were studied. Neither TI nor S dogs developed spontaneous atrial arrhythmias. Atrial overdrive (OD) and premature stimulation (PS) were used to initiate and terminate arrhythmias. At 2 weeks and for 20 to 30 weeks after surgical preparation, TI dogs were more susceptible to arrhythmias than S dogs. The duration of arrhythmias exceeded 10 minutes more often in TI dogs than in S dogs. Sixty-one percent of all arrhythmias in the TI dogs had rates of 320-450 impulses/min, and electrogram and ECG characteristics of atrial flutter (type II rhythm), whereas no S dogs developed rhythms ...
Based on observations that as cardiac output (as determined by an artificial pump) was experimentally increased the right atrial pressure decreased, Arthur Guyton and coworkers proposed an interpretation that right atrial pressure represents a back p
Catchable fatal error: Object of class WP_Error could not be converted to string in /home/lawrence/public_html/wp-content/themes/conduit/functions/breadcrumbs.php on line 68 ...
In a patient with diminished right-sided cardiac output or high right atrial pressure, once the contrast material is injected there is reflux of contrast material into the inferior vena cava and hepatic veins. This is one of the radiographic feat...
The present study investigates for the first time the relationship of LA volumes and reservoir function with subclinical cerebrovascular disease. We demonstrated that greater LA volumes and smaller LA reservoir function are associated with SBI and WMHV. In addition, we showed that LAVmin is a stronger predictor of silent cerebrovascular lesions than the commonly used LAVmax, and that its significant association with subclinical brain disease persisted after controlling for potential confounders and risk factors.. The mechanisms linking an increase in LA volume with cerebrovascular disease are not completely understood, but it is reasonable to hypothesize that the mechanisms suggested for the relationship between LA size and stroke may, at least in part, apply to silent cerebrovascular disease as well. This is biologically plausible considering that: 1) subjects with subclinical brain lesions are more likely to experience an overt cerebrovascular event; and 2) subclinical and overt ...
Detecting left atrial enlargement is frequently suspected in line with the presentation of signs and symptoms of the underlying cardiogenic condition. Once other tests addressing other complications are carried out to assist eliminate any potentially existence-threatening disorders, additional testing searching in the structure from the heart can be achieved to find out if left atrial enlargement exists.. Probably the most generally done test to identify left atrial enlargement is applying imaging methods known as echocardiograms. To control your emotions by utilizing seem waves to consider images of the center structures. Using other imaging tests, namely CT or MRI scans, may also be used to identify left atrial enlargement.. With respect to the underlying condition, treatment will normally follow. For instance, treating high bloodstream pressure calls for the effective use of bloodstream pressure medication for example beta-blockers and diuretics. Also, maintaining a healthy diet plan, ...
This study aimed to assess the changes of RA function in patients with obstructive sleep apnea syndrome (OSAS) using velocity vector imaging (VVI) and to evaluate the application of VVI technology. According to the apnea-hypopnea index (AHI), 71 patients with OSAS were divided into three groups: mild, moderate, and severe. A total of 30 cases of healthy subjects were enrolled as the control group. Digital images of apex four-chamber views were acquired to measure the right atrium (RA) linear dimensions and volume parameters including RA longitudinal diameter (RAL), transverse diameter (RAT), RA maximum volume (Vmax), RA minimum volume (Vmin), right atrial volume before contraction (Vpre). Right atrial volume parameters were corrected by body surface area (VImax, VImin, VIpre). The total right atrial emptying fraction (RATEF), right atrial passive emptying fraction (RAPEF), right atrial active contraction emptying fraction (RAAEF) were calculated. The VVI data measuring right atrial global strain (RA-GLS
We previously reported the use of a catheter system to damage the tricuspid valve and create infectious endocarditis (IE) in an animal model. The current study aims to create a faint IE model suitable for antibiotic prophylaxis using a low bacterial inoculum. We also aim to explore a way to quantitatively assess valvular impairment and to predict the success of the IE models during catheterization. Ninety rabbits were assigned to two groups according to the density of bacteria inoculated (1 × 105 CFU for Group A and 1 × 104 CFU for Group B). A catheter system consisting of a polyethylene catheter and a guide wire were used to damage the valve. The catheter system was passed through the rabbits tricuspid valves under echocardiographic guidance. A pressure transducer was used to assess right atrial pressure (PRA) before and just after valvular damage to calculate the pressure alterations (ΔPRA). The animals in group A and B were divided into 3 subgroups according to the ΔPRA (0-5 mmHg for Groups A1
The most common cause of RV failure is LV failure. In a sick patient, atrial flutter is definitely sufficient to result in elevated left sided pressures, with pulmonary edema and then subsequent right sided fluid overload. There are only 4 causes of LV failure: valve (valves were ok), systolic dysfct (it was good enough), diastolic dysfct (no evidence of this) and dysrhythmia (this was present). Turns out it had been present for a week, resulting in slow accumulation of fluid (this also explains the pleural effusions).. Delete ...
In patients with MS, several studies have demonstrated that LA enlargement is a marker of increased thromboembolic risk (4,6,7,9,11,25,26). However, the great majority of studies considered LA size or volume as an indicator of risk. This study aimed to look specifically at LA shape and not just LAVs and LA function in predicting stroke. As LA dilation may not occur in a uniform fashion, LA shape might be a better measure of the pattern of LA remodeling and a better predictor of embolic risk than absolute LAV.. The results of this study show that the atrial shape adds incremental value in predicting embolic events. Additionally, in agreement with a recently published study (27), we found that LA reservoir function was also associated with an increased risk for ECE. Although the LA has 3 major roles that affect LV filling, its reservoir function represents the most important component of the LA function in MS. LA contractile force cannot overcome the mechanical obstruction across the valve and ...
... : Cardiac catheterization. Figure 3.1: right atrial pressure waveform with a steep y descent (dashed arrow). Figure 3.2: right ventricular pressure waveform with a dip and plateau sign (solid arrow). Equalization of enddiastolic pressures ...
Article Double potential step chronocoulometric studies to determine the role of thiocyanate in electroanalytical determination of gallium in Pu-Ga and U-Ga alloys. Two rapid, selective and simple methods are developed for the determination of galliu...
Does anyone know what CM is supposed to look like right before you are due to start your period? - what does it look like right before your period starts ...
A cardiac function curve is a graph showing the relationship between right atrial pressure (x-axis) and cardiac output (y-axis). Superimposition of the cardiac function curve and venous return curve is used in one hemodynamic model. It shows a steep relationship at relatively low filling pressures and a plateau, where further stretch is not possible and so increases in pressure have little effect on output. The pressures where there is a steep relationship lie within the normal range of right atrial pressure (RAP) found in the healthy human during life. This range is about -1 to +2 mmHg. The higher pressures normally occur only in disease, in conditions such as heart failure, where the heart is unable to pump forward all the blood returning to it and so the pressure builds up in the right atrium and the great veins. Swollen neck veins are often an indicator of this type of heart failure. At low right atrial pressures this graph serves as a graphic demonstration of the Frank-Starling mechanism, ...
The right atrium is one of the four chambers of the heart. The heart is comprised of two atria and two ventricles. Blood enters the heart through the two atria and exits through the two ventricles. Deoxygenated blood enters the right atrium through the inferior and superior vena cava. The
Hi, new pool owner here. I just recently got a Taylor K2006 test kit and I wanted to post my numbers to see if anyone had any advice. I have an SWG and a 9,400 gallon round above ground pool. FC 10 CC 1 PH 7.4 TA 120 CYA 50 Salt 3300 ppm I didnt get the CH number yet. I recently just got done fighting algae so I know my FC is kind of high right now. The pool is still a little cloudy though.
สโมสรอินเตอร์ มิลาน ทีมชื่อดังแห่งเวทีกัลโช่ เซเรีย อิตาลี มีข่าวว่าพวกเขาทำการติดต่อไปหา เลโอนาร์โด้ ชาร์ดิม นายใหญ่ของสโมสรอาแอส โมนาโก ทีมในลีกเอิง ฝรั่งเศส เพื่อหวังคว้าตัวมาคุมทีมในซีซั่นหน้า หลังจากที่พวกเขา อดได้ อันโตนิโอ คอนเต้,เมาริซิโอ โปเช็ตติโน่ รวมไปถึง ดีเอโก้ ซิเมโอเน่ แน่นอนแล้ว และทีมงูใหญ่ ...
What makes a fully effective pre-workout are the right ingredients, at the right doses, in the right forms - all of these found in Pre JYM - and taken at the right times.
Establishing adequate venous access, in some cases through a central venous catheter, is essential to ensure ease of fluid replacement and adequate monitoring of the patient. In patients with ascites, the elderly patients, and those with associated medical conditions such as ischaemic heart disease, the right atrial pressure may not accurately reflect left sided heart pressures so fluid replacement should be monitored with a Swan- Ganz catheter.. Detailed attention to fluid replacement is important for any gastrointestinal bleed and even more so in patients with established chronic liver disease. These patients may have reduced vascular tone and fail to mobilise pooled venous blood from the splanchnic circulation.3Failure to achieve prompt volume replacement may jeopardise renal and hepatic function, a major factor in the morbidity and mortality associated with a variceal bleed.3It is equally important to avoid overfilling as this may precipitate rebleeding, so the right atrial pressure should ...
Right atrial appendage aneurysm (RAAA) is rare with fewer than 20 cases reported in the literature. We sought to systematically review the published cases of RAAA in terms of demographics, clinical characteristics, treatment, complications, and outco
Randomized controlled trial of 433 patients at 26 sites randomized to receive therapy guided by clinical assessment and a PAC or clinical assessment alone. The target in both groups was resolution of clinical congestion, with additional PAC targets of a pulmonary capillary wedge pressure of 15 mm Hg and a right atrial pressure of 8 mm Hg. Medications were not specified, but inotrope use was explicitly discouraged. Results: PAC did not significantly affect the primary end point of days alive and out of the hospital during the first 6 months (p = 0.99), mortality (p = 0.35), or number of days hospitalized (p = 0.67). In-hospital adverse events were more common among patients in the PAC group (21.9% vs. 11.5%, p = 0.04), although there were no deaths related to PAC use.. ...
Relationships between P wave dispersion, atrial electromechanical delay, left atrial remodeling, and NT-proBNP levels, in patients with hypertrophic cardiomyopathy. Tuluce K, Ozerkan F, Yakar Tuluce S, Yavuzgil O, Gurgun C, Bilgin M, Kahya Eren N, Kocabas U, Nalbantgil S, Soydas Cinar C. Cardiol J. 2015;22(1):94-100. doi: 10.5603/CJ.a2014.0025. Epub 2014 Mar 27 ...
Doctors give trusted, helpful answers on causes, diagnosis, symptoms, treatment, and more: Dr. Krauser on numbness and tingling on right side of body: Impossible to say without more information. However if it has persisted greater than 2 weeks, it should be evaluated. Could be anything from a temporary viral inflammation to ms, to a brain tumor.
το κείμενο με τίτλο Guided in the right direction σχετίζετε με Τεχνίτη Νοημοσύνη και Ρομποτική
... (CVP) is the blood pressure in the venae cavae, near the right atrium of the heart. CVP reflects the amount of blood returning to the heart and the ability of the heart to pump the blood back into the arterial system. CVP is often a good approximation of right atrial pressure (RAP),[1] although the two terms are not identical, as a pressure differential can sometimes exist between the venae cavae and the right atrium. CVP and RAP can differ when arterial tone is altered. This can be graphically depicted as changes in the slope of the venous return plotted against right atrial pressure (where central venous pressure increases, but right atrial pressure stays the same; VR = CVP − RAP).. CVP has been, and often still is, used as a surrogate for preload, and changes in CVP in response to infusions of intravenous fluid have been used to predict volume-responsiveness (i.e. whether more fluid will improve cardiac output). However, there is increasing evidence that CVP, whether ...
Electrical conduction is very rapid and highly anisotropic in atrial fiber bundles, such as the crista terminalis. In contrast to left ventricular myocardium in which the ratio of longitudinal to transverse conduction velocities is approximately 3, propagation velocity in the crista terminalis is approximately 10 times greater in the longitudinal than in the transverse direction. To elucidate potential determinants of these distinct conduction properties, we characterized structural and molecular features of intercellular coupling in the crista terminalis and left ventricular myocardium of the canine heart. Analysis of the number and spatial orientation of myocyte interconnections at gap junctions revealed that a typical left ventricular myocyte was connected to 11.3 +/- 2.2 other myocytes. Approximately equal numbers of connections occurred between ventricular myocytes juxtaposed in side-to-side and end-to-end orientation. In contrast, a typical myocyte of the crista terminalis was connected to ...
TY - JOUR. T1 - Associations of electrocardiographic P-wave characteristics with left atrial function, and diffuse left ventricular fibrosis defined by cardiac magnetic resonance. T2 - The PRIMERI study. AU - Win, Theingi Tiffany. AU - Venkatesh, Bharath Ambale. AU - Volpe, Gustavo J.. AU - Mewton, Nathan. AU - Rizzi, Patricia. AU - Sharma, Ravi K.. AU - Strauss, David G.. AU - Lima, Joao A.. AU - Tereshchenko, Larisa G.. PY - 2015/1/1. Y1 - 2015/1/1. N2 - BACKGROUND: Abnormal P-terminal force in lead V1 (PTFV1) is associated with an increased risk of heart failure, stroke, atrial fibrillation, and death. OBJECTIVE: Our goal was to explore associations of left ventricular (LV) diffuse fibrosis with left atrial (LA) function and electrocardiographic (ECG) measures of LA electrical activity. METHODS: Patients without atrial fibrillation (n = 91; mean age 59.5 years; 61.5% men; 65.9% white) with structural heart disease (spatial QRS-T angle ≥105° and/or Selvester QRS score ≥5 on ECG) but LV ...
Pericardiotomy definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
We know the atrial pressure wave forms vary between right and left atrium .In the right atrium a waves are prominent and taller than v waves, while the reverse is true in left atrium . The reasons for tall left atrial v waves are V waves are passive atrial filling waves and are timed during ventricular…
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ANSWER: A third meaning is: doing something. Example: What are you up to right now? So, to answer your second question, it can mean, what are your plans/what are you doing today, although it sounds more natural to use it when asking someone what he is doing right now. Up to is common way to ask
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Associate Professor of Pharmacology and Toxicology Director, Mass Spectrometry Core Facility (MSCF) Associate Director, Mass Spectrometry Resources, Mississippi Center for Heart Research (MCHR) Office: R401 Lab: R402; R416; R417(601) 815-1268EmailCVBibliographyResearch interestsUnderstanding disease models and mechanisms (hypertension, cardiovascular, obesity, diabetes and kidney disease)Characterization of biomarkers in human illness/diseaseUnderstanding and preventing adverse drug responses (ADRs)Disparities in health and treatment outcomesPharmacokinetics/pharmacodynamics/drug metabolismAlcohol/drug-induced hepatotoxicity mechanismsProteomics/peptidomics/lipidomics/metabolomicsMass spectrometry: methods, data collection and analysisUMMC Mass Spectrometry Core Facility (MSCF)Current researchMy research interests are in understanding the dynamic interplay between protein structure and conformation and how this is manifested in protein function. Cytochrome P450s became my research focus while at the
August, 2008. ABOUT ME: Sometimes without impetus, I move to the middle of our living room floor and do gymnastics. I dont think Ive successfully done a back walkover since I was sixteen, or even a back bend for that matter, but hand stands, splits (sort of), pirouettes, anything that my timber body can handle I attempt. Yes, timber. The opposite of limber. As flexible as a tree trunk. One time last year I showed someone in the hallway of our office how to do a round-off even though I hadnt done one in probably a bakers dozen of years. I also wore my triathlon wetsuit to the office because I was dared. Everything is funnier when someones wearing a wetsuit. The wetsuit and the round-off occurred on different days, but next time that might not be the case.. I am a licensed speech-language pathologist, which Im pretty sure means, based on initial letter, that I can wear the same logo as Superman. In 2004, I moved to Pittsburgh and started school for the 21st time. I am working towards my ...
A biventricular cardiac prosthesis has a flow balance control system to balance blood flow through the left and right sides of the prosthesis to maintain a patients left atrial pressure within physiologic bounds. The prosthesis can be configured to have flow characteristics so that a signal representative of the difference in hydraulic pumping pressures on the left and right sides of the prosthesis is representative of the difference between left and right atrial pressures of a patient having the prosthesis implanted. This signal can be used as a control signal to drive the prosthesis so that left atrial pressure is approximately equal to right atrial pressure, and within physiologic bounds. A specific prosthesis includes left and right pumping sections, each having a blood pumping chamber and a hydraulic fluid chamber, with a reciprocating hydraulic pump driving systole alternately on the right and left sides. A hydraulic balance chamber is hydraulically coupled to the right hydraulic fluid chamber
Figure 2-35 Various locations of left ventricular false tendons. A. Two false tendons arrows from posteromedial mitral papillary muscle PM to ventricular
Obesity is a major risk factor for left atrial enlargement, which increases the risk of atrial fibrillation, stroke and death, a new study shows.
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Originally Posted by zboss This was just one opinion and not mine. However, there is another thread on the exumas going on right now and the development associated with it. Im not surprised that the,
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Существует такая услуга - добровольное медицинское обслуживание (или ДМО). Она предполагает, что вы вносите небольшую сумму за абонемент и посещает врачей в течение года бесплатно. Однако соцопросы показывают, что лишь 4% жителей города знают о ее существовании. Почему? Потому что частным клиникам выгоднее брать плату за каждое посещение. А если какой-нибудь сотрудник клиники попытается посоветовать ...
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The methodologic limitations of "low density" in vivo mapping in humans, however, should not be underestimated. Though the observation of split potentials associated with an alteration of the activation sequence of the second component strongly suggests conduction block, a marked conduction delay cannot be excluded. Actually, conduction delays have been proved to be the cause of double potentials in different settings (i.e., intrahisian "block"). However, the alteration of the activation sequence of the second component gives further evidence of conduction block and findings from experimental studies with high density epicardial mapping support the interpretation of our observations (15,16,32).. Aside from that, conduction was determined during pacing in the lateral right atrium adjacent to the anterior edge of the CT in patients with documented atrial tachyarrhythmias. Pulse propagation in the opposite direction (from posterior to anterior) or in healthy subjects or after pacing apart from the ...
There is a hypodense mass lesion present within the lumen of the right atrium and which appears to adhere to the posterior wall. There is no atrial enlargement. The heart is normal in size and no pericardial effusion is present.
Mouse Heart, left and right atrium Total RNA is extracted from freshly harvested tissues of single healthy normal donor using classical guanidine isothiocyanate-phenol:chloroform extraction method which allows the rapid isolation of total RNA including microRNAs. RNA is treated with RNase-free DNase-1to remove residual DNA, precisely quantified, and stored at -80oC. Quality Control: The integrity of
Sorry to hear about your problem. Just wanted to ask you a few questions. How old was your mother when she died? Also, do you smoke, have been exposed to smoke for a long period of time, or have any chronic pulmonary problems? The reason I ask these questions is that it usually takes years (more than your age) to develop atrial enlargement from COPD. Also, it is really important to find out about your family history of cardiac problems, especially serious ones at an early age. This is definitely something your doctor needs to know. If I were you, I would go to a cardiologist as soon as you get insurance. If you have anymore symptoms prior to getting insurance, go the the ER. I know its expensive, but it just may save your life. Dont mean to scare you, but anything to do with the heart can be very serious. Many times when someone of your age complains of any type of chest pains, doctors may assume its anxiety but never let anyone assume that. Have all the tests done just to be safe. Anyway, ...
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The Mammalian Phenotype (MP) Ontology is a community effort to provide standard terms for annotating phenotypic data. You can use this browser to view terms, definitions, and term relationships in a hierarchical display. Links to summary annotated phenotype data at MGI are provided in Term Detail reports.
This is hard to describe but I will try my best. I am 31 yrs old. I have endless problems with my right ear, right side of throat, and right side of tongue. I have seen a ent. Have another appt schedu...
I am flying high right now! I just recieved a call from Dr. Lenkes nurse, and she made me an appt. for the 16th of May with Dr. Lenke. Isnt this great news! (I hope anyway).Its the consultation. I think that in my case he may be the one to help ME. Anyway, I just wanted you all to know. Got to go rest for a while as I tire easy. But I will be on here again. I want to thank everyone for being here for me!! Gentle Hugs to you all! Linda
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Nicki Minaj returned to "The Ellen DeGeneres Show" Thursday (May 10), where she performed a medley of her new hits "Right By My Side" and "Starships ...
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"Thyroid Function Abnormalities during Amiodarone Therapy for Persistent Atrial Fibrillation". The American Journal of Medicine ... Thyroid function tests[edit]. Further information: Thyroid function tests. There are several hormones that can be measured in ... Low function[edit]. Main article: Hypothyroidism. Hypothyroidism is a state in which the body is not producing enough thyroid ... High function[edit]. Main article: Hyperthyroidism. Hyperthyroidism is a state in which the body is producing too much thyroid ...
The discovery of right atrial mechanical function is a pivotal discovery in his medical research work. He is an editor for the ... He is best known for his discovery of the mechanical function of atrial chambers of the heart. With experimental evidence on ... atrial fibrillation and in improving the design and functioning of prosthetic hearts. Rai captained the Bangalore University ... The functioning of the Heart: Dr. Dinker Rai's Discovery- Bhavan's Journal VOL .5:9&10. February 1986 Newspaper Ten Deccan ...
Gu J.Y., Xu J.H., Yu H., Yang Y.Q. (2012). Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation.. ...
"Atrial endocrine function in humans with artificial hearts." ; Schwab T.R., Edwards B.S., DeVries W.C., Zimmerman R.S., Burnett ... February 1987 ; "Artificial Organs" ; PMID 3566584 "A clinical estimation model for noninvasive determination of atrial ...
Normal atrial function is essential for embryogenesis, as inactivation of the MYL7 gene was embryonic lethal at ED10.5-11.5. ... Huang C, Sheikh F, Hollander M, Cai C, Becker D, Chu PH, Evans S, Chen J (December 2003). "Embryonic atrial function is ... Atrial Light Chain-1 (ALC-1), also known as Essential Light Chain, Atrial is a protein that in humans is encoded by the MYL4 ... Shift in atrial myosin heavy chains and in ventricular myosin light chains". European Heart Journal. 5 Suppl F: 85-93. doi: ...
"Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation". Human Molecular Genetics. 15 (14 ... Mutations in this gene have been related to both atrial fibrillation and sudden cardiac death. KCNA5 are also key players in ... It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells ... Potassium channel subunits capable of functioning as Src homology 3-dependent adaptors". Proceedings of the National Academy of ...
"Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation". Heart Rhythm. 5 (3): 427-35. doi ... Inherited sequence variants in human KCNE5 are associated with atrial fibrillation and Brugada syndrome. Atrial fibrillation is ... "Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation". Heart Rhythm. 5 (3): 427-35. doi ... "Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation". American Journal of Human ...
Long-term expression of isomyosins and myoendocrine functions in ectopic grafts of atrial tissue. Proc Natl Acad Sci U S A. ...
"Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation". American Journal of Human ... "Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation". Biomarkers ... As observed for hERG mutations, KCNE2 loss-of-function mutations are associated with inherited LQTS, and hERG-KCNE2 channels ... KCNE2 is also expressed in atrial and ventricular cardiomyocytes, the pancreas, pituitary gland, and lung epithelium. In situ ...
Atrial fibrillation Abnormalities in the function of MS channels can cause: Neuronal disease Muscular degeneration. Cardiac ... MSCs function as mechanotransducers capable of generating both electrical and ion flux signals as a response to external or ... In Bacteria and Archaea the function of these channels is conserved and it has been demonstrated that they play a role in ... Although MS vary in many aspects, structures and functions, all the MS studied to date share an important feature: in a process ...
... has exactly the opposite function of the atrial natriuretic hormone secreted by the heart. Aldosterone is part of ... Aldosterone is a function of the inverse of the sodium intake as sensed via osmotic pressure. The slope of the response of ... The amount of aldosterone secreted is a direct function of the serum potassium as probably determined by sensors in the carotid ... they share 11β-hydroxylation and 18-hydroxylation functions), but aldosterone synthase is also able to perform an 18-oxidation ...
Tuomi JM, Chidiac P, Jones DL (February 2010). "Evidence for enhanced M3 muscarinic receptor function and sensitivity to atrial ... RGS2 functions as a GTPase Activating Protein (GAP) which acts to increase the natural GTPase activity of the Gα subunit. By ... There has also been some evidence of a role of RGS2 in atrial arrhythmias where RGS2 deficient mice exhibited prolonged and ... 1998). "RGS2/G0S8 is a selective inhibitor of Gqalpha function". Proc. Natl. Acad. Sci. U.S.A. 94 (26): 14389-93. doi:10.1073/ ...
The AV node connects the atrial and ventricular chambers. It functions to carry the electrical impulse from the atria to the ... Function. The common ostrich is an endotherm and maintains a body temperature of 38.1-39.7 °C (100.6-103.5 °F) in its extreme ... Kidney function. Common ostrich kidneys are fairly large, and so are able to hold significant amounts of solutes. Hence, common ... The wings also function as stabilizers to give better maneuverability when running. Tests have shown that the wings are ...
"A gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects". ... Proper function of Tbx20 is essential because it controls other genes that regulate cardiomyocyte proliferation, such as Tbx2 ... Studies in mouse, human and fruitfly have shown that this gene is essential for early heart development, adult heart function ... function and adaptation". Development. 132 (10): 2451-62. doi:10.1242/dev.01799. PMID 15843414. Takeuchi JK, Mileikovskaia M, ...
"Effects of human atrial natriuretic peptide on cardiac function and hemodynamics in patients with high plasma BNP levels". Int ... This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell ... Mutations resulting in loss-of-function of caveolin-3 cause cardiac myocyte hypertrophy, dilation of the heart, and depression ... Disruption of caveolin-3 disturbs the structure of cardiac caveolae and blocks atrial natriuretic peptide (ANP) expression, a ...
... is a function of atrial contraction. The ratio between e' and a' is also a measure of diastolic function, in addition to the ... Before the advent of tissue Doppler, systolic function was usually assessed with Ejection fraction (EF), and diastolic function ... this pressure difference is both a function of the pressure drop during early relaxation and the initial atrial pressure. In ... In the right ventricle this is not an important principle, as the right atrial pressure is the same as central venous pressure ...
... of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function". ... all notch proteins fail to function properly. As yet, the manner by which the glycosylation of notch affects function is not ... Studies have revealed that both loss- and gain-of-function of the Notch pathway results in defects in AV canal development. In ... The addition of O-fucose by POFUT1 is absolutely necessary for notch function, and, without the enzyme to add O-fucose, ...
5p fails as a biomarker for systemic ventricular function in adults after atrial repair for transposition of the great arteries ... MicroRNAs function to regulate the expression levels of other genes by several mechanisms. MicroRNA 1. 2. 3. 4. 5. 6. 7. 8. 9. ...
... gain-of-function KCNE1 mutations are associated with early-onset atrial fibrillation. A common KCNE1 polymorphism, S38G, is ... Atrial KCNE1 expression was downregulated in a porcine model of post-operative atrial fibrillation following lung lobectomy. ... Han HG, Wang HS, Yin Z, Jiang H, Fang M, Han J (20 October 2014). "KCNE1 112G>a polymorphism and atrial fibrillation risk: a ... KCNQ1 is also essential for the normal function of many different epithelial tissues, but in these non-excitable cells it is ...
Vengen ØA, Ellingsen Ø, Lande K, Ilebekk A. Significance of right atrial function during right sided inotropic stimulation of ... Vengen ØA, Ellingsen Ø, Ilebekk A. Forward diastolic flow in pulmonary artery induced by right atrial contraction of in situ ... Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice. J Appl Physiol ... He currently participates in the HUNT-3 survey of physical activity, aerobic capacity, and endothelial function in Nord- ...
Occasionally pacing of the atrium at a rate higher than the JET may allow improved cardiac function by allowing atrial and ... as they do during atrial fibrillation or atrial flutter), the AV node will limit the electrical activity that conducts to the ... This function of the AV node is important, because if the signals generated in the atria of the heart were to increase in rate ... There may be atrio-ventricular disassociation with more ventricular signals then atrial signals. The cause of JET is felt to be ...
A cardiac function curve is a graph showing the relationship between right atrial pressure (x-axis) and cardiac output (y-axis ... At low right atrial pressures this graph serves as a graphic demonstration of the Frank-Starling mechanism, that is as more ... This allows the heart to cope with the required cardiac output at a relatively low right atrial pressure. We get what is known ... The pressures where there is a steep relationship lie within the normal range of right atrial pressure (RAP) found in the ...
The AV node connects the atrial and ventricular chambers. It functions to carry the electrical impulse from the atria to the ... The wings also function as stabilizers to give better maneuverability when running. Tests have shown that the wings are ... It is located in the endocardium of the atrial surface of the right atrioventricular valve. It is not covered by connective ... However, the common ostrich shows no nasal glandular function in regard to this homeostatic process. Even in a state of ...
Theodorakis GN, Panou F, Markianos M, Fragakis N, Livanis EG, Kremastinos DT (February 1997). "Left atrial function and atrial ... and decreased left atrial total emptying fraction associated with ventricular pacing. The loss of physiologic timing of atrial ... Atrial contraction against a closed tricuspid valve can cause pulsation in the neck and abdomen, headache, cough, and jaw pain ... That's due to increase in left atrial pressure and left ventricular filling pressure, which is due to decreased cardiac output ...
The Shimmer3 ECG unit can be applied to a variety of applications such as heart function monitoring , atrial fibrillation , ...
It is also requested routinely in conditions linked to thyroid disease, such as atrial fibrillation and anxiety disorder. A TFT ... Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. TFTs may be ... American Thyroid Association: Thyroid Function Tests. Posted on June 4, 2012, seen on January 9, 2013. Thyroid function panel ... Its measurement is the most sensitive test for thyroid hormone function. TSH is produced in the pituitary gland. The production ...
A balloon atrial septostomy is also done. This ensures that there is enough of a connection between the two atria of the heart ... as a result of the inability of the left heart to pump enough blood to sustain normal organ function. In fetal life, this is ... The atrial septum is removed, the aortic arch is reconstructed to remove any hypoplasia, and then the main pulmonary artery is ...
ISBN 1-59745-238-6. Meinertz T, Willems S (December 2008). "Die Behandlung von Vorhofflimmern im Alltag" [Treatment of atrial ... The blockade of only beta receptors increases blood pressure, reduces coronary blood flow, left ventricular function, and ... Indications for beta blockers include: Angina pectoris (contraindicated for Prinzmetal's angina) Atrial fibrillation Cardiac ... and prolonged atrial refractory periods. Sotalol, in particular, has additional antiarrhythmic properties and prolongs action ...
Effect of low dose infusion of atrial natriuretic peptide on renal function in man. L. R. Solomon, J. C. Atherton, H. Bobinski ... Effect of low dose infusion of atrial natriuretic peptide on renal function in man ... Effect of low dose infusion of atrial natriuretic peptide on renal function in man ... Effect of low dose infusion of atrial natriuretic peptide on renal function in man ...
What is atrial natriuretic factor? Meaning of atrial natriuretic factor as a finance term. What does atrial natriuretic factor ... Definition of atrial natriuretic factor in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... a business that buys in bulk and performs a WHOLESALING function.. *a business that buys trade debts from client firms (at some ... redirected from atrial natriuretic factor). Also found in: Dictionary, Thesaurus, Medical, Legal, Acronyms, Encyclopedia. ...
Learn more about Atrial Septal Defect Repair in Children -- Open Heart Surgery at Medical City Dallas DefinitionReasons for ... Echocardiogram -a test that uses sound waves to visualize heart functioning * Electrocardiogram (ECG, EKG)-a test that records ... An atrial septal defect is a hole in the wall between the 2 upper chambers (right and left atriums) of the heart. Open heart ... This machine will take over the functions of the heart and lungs. The heart will be stopped to do surgery. ...
... echocardiography may allow transthoracic detection of left atrial thrombi and assessment of left atrial appendage function. ... 172 Patients with atrial fibrillation and/or atrial flutter who were scheduled for cardioversion and/or overdrive stimulation ... Keywords: Kardioversion, transthorakale Echokardiographie, Vorhofflattern, Vorhofflimmern, atrial fibrillation, atrial flutter ... Transesophageal echocardiography has been suggested for guiding cardioversion in patients with atrial fibrillation and atrial ...
Time course of right ventricular remodeling after percutaneous atrial septal defect closure: assessment of regional deformation ... Quantitative assessment of the right ventricular (RV) function in atrial septal defect (ASD) patients before and after closure ... The aim of this study was to assess the regional RV function in ASD patients, to evaluate the extent and time course of RV ... RV apical S showed strong correlations with systolic pulmonary artery pressure and global RV systolic function indices.. ...
To obtain normal values for left atrial function noninvasively, volumes of the left atrium and ventricle were calculated in 52 ... Atrial Function*. Cardiac Volume. Echocardiography*. Female. Humans. Male. Middle Aged. Myocardial Contraction. Reference ... These values are similar to those reported in studies in which left atrial function was calculated from contrast angiography.. ... To obtain normal values for left atrial function noninvasively, volumes of the left atrium and ventricle were calculated in 52 ...
Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European ... OBJECTIVE: This study aimed to identify novel GATA5 mutations that underlie familial atrial fibrillation. METHODS: A total of ... GATA4 loss-of-function mutations in familial atrial fibrillation. Clin Chim Acta. 2011;412(19-20):1825-30, http://dx.doi.org/ ... Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339(10): ...
Objective: To examine the feasibility of using SI and SR to evaluate phasic atrial function in patients with mild hypertension ... measure regional myocardial deformation and may be a new technique to assess phasic atrial function. ... The following left atrial (LA) volumes were measured: (a) maximal LA volume or Volmax; (b) minimal LA volume or Volmin; (c) ... No significant difference was present in S-Sr, A-Sr or global atrial strain between the normal and HT cohorts. ...
... causes tachycardia-induced atrial electrical remodeling, contributing to the progressive nature of the arrhythmia. Ventricular ... Atrial tissue from 1-week atrial-tachypaced dogs with ventricular rate control similarly showed upregulation of alpha SMA ... METHODS: Cultured canine atrial fibroblasts were treated with medium from rapidly-paced atrial cardiomyocytes, non-paced ... 18460289 - Atrial fibrillation and congestive heart failure.. 15851239 - Late recurrent arrhythmias after ablation of atrial ...
Our results indicate that Hrt2 acts in the ventricular myocardium to repress atrial gene expression, thereby functioning as a ... Repression of Atrial Gene Expression by Hrt2.. Based on the up-regulation of multiple atrial genes including Mlc1a, Mlc2a, Sln ... These findings reveal a ventricular myocardial cell-autonomous function for Hrt2 in the suppression of atrial cell identity and ... Repression of Atrial Genes by Hrt2.. To determine whether Hrt2 was sufficient to repress endogenous atrial gene expression, we ...
... Fang Yuan1#, Lan Zhao2#, Juan Wang3, Wei ... PITX2c Loss-of-Function Mutations Responsible for Congenital Atrial Septal Defects. Int J Med Sci 2013; 10(10):1422-1429. doi: ... These findings firstly link PITX2c loss-of-function mutations to atrial septal defects in humans, which provide novel insight ... Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is ...
M XiaQ JinS BendahhouY HeMM LarroqueY ChenQ ZhouY YangY LiuB LiuA Kir2.1 gain-of-function mutation underlies familial atrial ... Li, J., Liu, W., Yang, Z., Yang, Y.Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation. ... Li, J., Liu, W., Yang, Z., Yang, Y.Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation. ... Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation. *Authors: *Jian Li ...
Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children. Peter L. Stavinoha, ... Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children ... Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children ... Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children ...
Heart Rate Increase Pindolol Cardiac Pacemaker Pump Function Pacemaker Activity These keywords were added by machine and not by ...
Keywords: thyroid function, epicardial fat, atrial fibrillation, causal mediation analysis ... The underlying mechanism of the association between thyroid function and atrial fibrillation (AF) is poorly understood, but ... We report no mediating role of EAT in the association of thyroid function with AF, but found evidence for a suggested ... We found no evidence of a mediating role of EAT in the association of thyroid function with AF (mediated interaction 1.6%, pure ...
... Rundqvist, Louise Jönköping ... 50 mL/m(2) (P amp;lt; 0.001), left atrial volume 27 vs. 19 mL/m(2) (P amp;lt; 0.001), and right ventricular (RV) and right ... The aims of the study were to explore the effects of long-term endurance exercise on atrial and ventricular size and function ... Further, we found improved systolic function in the active group compared with controls: left ventricular ejection fraction 61 ...
Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement ( ... left atrial (LA) function was assessed at baseline and after 12 months treatment using 2-D echocardiography and interpreted ... Evaluate the effects of dronedarone versus placebo on left atrial function;. *Evaluate the effects of dronedarone versus ... Changes From Baseline in Left Atrial Function [ Time Frame: baseline (before randomization) and post-baseline (after 3-12 ...
... and Function. Petr Kuchynka,1,2 Jana Podzimkova,1 Martin Masek,3 Lukas Lambert,3 Vladimir Cerny,3 Barbara Danek,1 and Tomas ... atrial fibrillation require the need for detailed knowledge of left atrial and pulmonary venous morphology as well of atrial ... This review article discusses the role of cardiac magnetic resonance and computed tomography in assessment of left atrial size ... The Role of Magnetic Resonance Imaging and Cardiac Computed Tomography in the Assessment of Left Atrial Anatomy, Size, ...
"Right atrial MR imaging studies of cadaveric atrial casts and comparison with right and left atrial volumes and function in ... "Left atrial function and scar after catheter ablation of atrial fibrillation," Heart Rhythm, vol. 5, no. 5, pp. 656-662, 2008. ... "Left atrial transport function in myocardial infarction. Importance of its booster pump function," The American Journal of ... "Assessment of left atrial volume and function in patients with permanent atrial fibrillation: comparison of cardiac magnetic ...
Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis. Divya ... Background: Left atrial (LA) function by volume and strain analysis in children has been little studied. LA dysfunction related ... Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis ... Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis ...
Recurrent pleural effusions, resistant atrial arrhythmias, and abnormal liver function tests: general medicine or cardiology? ... Recurrent pleural effusions, resistant atrial arrhythmias, and abnormal liver function tests: general medicine or cardiology? ... While awaiting an open pleural biopsy the patient was admitted with a further pleural effusion, jaundice, resistant atrial ...
2007) Improvement of atrial function and atrial reverse remodeling after cardiac resynchronization therapy for heart failure. J ... 1) several baseline data concerning atrial function are presented (left atrial volume index and mitral regurgitation severity ... Atrial Function in Patients Undergoing CRT Message Subject (Your Name) has forwarded a page to you from JACC: Cardiovascular ... In recent years, there has been growing interest in the potential impact of CRT on atrial function, but the state of knowledge ...
Patients with CHF commonly have atrial fibrillation or flutter (AF), which is frequently associated with, may be a marker for, ... of Atrial Fibrillation or Flutter Whether Systolic Function Is Preserved or Depressed" written by Jacob I. Haft, Louis E. ... Letter by Haft Regarding Article, "High Prevalence of Atrial Fibrillation Among Patients With Ischemic Stroke". Stroke, 2015. ... Letter by Haft Regarding Article,"High Prevalence of Atrial Fibrillation Among Patients With Ischemic Stroke" ...
Patients with CHF commonly have atrial fibrillation or flutter (AF), which is frequently associated with, may be a marker for, ... of Atrial Fibrillation or Flutter Whether Systolic Function Is Preserved or Depressed. World Journal of Cardiovascular Diseases ... of Atrial Fibrillation or Flutter Whether Systolic Function Is Preserved or Depressed ... Stroke Risk in Atrial Fibrillation Working Group (2008) Comparison of 12 Risk Stratification Schemes to Predict Stroke in ...
2012) The impact of atrial fibrillation ablation left atrial function: association with baseline left atrial function. Pacing ... left atrial. LAKE. left atrial kinetic energy. LAV. left atrial volume. LAVi. left atrial volume indexed to body surface area. ... 1999) Left atrial relaxation and left ventricular systolic function determine left atrial reservoir function. Circulation 100: ... atrial function is abnormal in HCM. Increases in booster pump function and impaired reservoir and conduit functions have been ...
  • Time course of right ventricular remodeling after percutaneous atrial septal defect closure: assessment of regional deformation properties with two-dimensional strain and strain rate imaging. (docphin.com)
  • Eroglu E, Cakal SD, Cakal B, Dundar C, Alici G, Ozkan B, Yazicioglu MV, Tigen K, Esen AM. Time course of right ventricular remodeling after percutaneous atrial septal defect closure: assessment of regional deformation properties with two-dimensional strain and strain rate imaging. (docphin.com)
  • We also believe that our results can apply to other populations, too, as they confirm similar findings of a link between atrial fibrillation and dementia in studies of people in Western and European countries," said Lip, who is also an adjunct professor at Yonsei University College of Medicine. (hon.ch)
  • All patients in sinus rhythm had preserved left and right atrial-filling waves through atrioventricular valves during atrial contraction. (diva-portal.org)
  • This was mainly achieved by increasing atrial contraction (A-wave), maintaining cardiac output by increasing heart rate. (bgu.ac.il)
  • Booster pump phase: contributing to RV filling in late diastole by atrial contraction. (elsevier.pt)
  • The reservoir and conduit phases are often termed passive phases, whereas the atrial contraction phase is considered the active phase. (elsevier.pt)
  • The other left atrial volumes were not altered after PMV. (biomedsearch.com)
  • In the 1995 participants (mean age 64.5 years) from the population-based Rotterdam Study, we measured thyroid function (thyroid-stimulating hormone, free thyroxine [FT and performed computed tomography to quantify EAT volumes. (dovepress.com)
  • We report no mediating role of EAT in the association of thyroid function with AF, but found evidence for a suggested interaction of FT4 with EAT volumes on AF risk. (dovepress.com)
  • Children with significant AS have abnormal LA function with higher phasic LA volumes, higher LA pump function, and lower strain-derived reservoir and conduit LA function. (ahajournals.org)
  • The left atrial volumes were calculated by the disk method. (kjim.org)
  • PPaV 1 and PTFV 1 were associated with an increase in LA volumes and decrease in LA emptying fraction and LA reservoir function. (elsevier.com)
  • LA volumes and LA emptying function across 3 phases of the cardiac cycles, and LV function were also quantified. (biomedcentral.com)
  • Recent findings suggest that left atrial (LA) function is more strongly related to adverse prognosis than LA volumes. (kb.se)
  • We aimed to evaluate the associations between LA volumes and Doppler filling indices with LA function. (kb.se)
  • Levels of natriuretic peptides tended to decrease in patients with stable sinus rhythm at one year compared to patients in atrial fibrillation. (diva-portal.org)
  • Left atrial function after the Cox maze procedure improved parallel to the recovery of sinus node function. (elsevier.com)
  • Conclusion: Progressive improvement of sinus node function and atrial contractions with significant functional normalization 1 year after the Cox maze procedure corresponded to functional reinnervation and recovery of the autonomic nervous system. (elsevier.com)
  • The three major types of atrial septal defect (ostium secundum, ostium primum and sinus venosus) account for 10% of all congenital heart defects and as much as 20-40% of congenital heart disease presenting in adulthood. (elsevier.pt)
  • LA function was analysed using strain derived from speckle tracking in sinus rhythm patients (n = 83). (nih.gov)
  • These findings support the relationship of LA dysfunction with HFPEF, suggesting that the analysis of LA function may be useful in sinus rhythm patients with new-onset dyspnoea. (nih.gov)
  • Second, all patients were at risk of developing kidney dysfunction, including those who started with healthy kidney function and those who started with moderate-severe kidney disease. (intermountainhealthcare.org)
  • Heart and kidney dysfunction are often correlated with each other, meaning if the function of either organ begins to decline, the other may be adversely affected, causing further organ damage. (intermountainhealthcare.org)
  • Release of atriopeptin in the rat by vasoconstrictors or water immersion correlates with changes in right atrial pressure. (springer.com)
  • It can be also estimated using various imaging techniques or other pressure readings such as PULMONARY CAPILLARY WEDGE PRESSURE (an estimate of left atrial pressure) and CENTRAL VENOUS PRESSURE (an estimate of right atrial pressure). (bioportfolio.com)
  • This review article discusses the role of cardiac magnetic resonance and computed tomography in assessment of left atrial size, its normal and abnormal morphology, and function. (hindawi.com)
  • B. Hoit, "Assessment of echocardiographic left atrial size: how accurate do we need to be? (hindawi.com)
  • In this elegant study, the authors performed a comprehensive assessment of LV function, showing that extensive LV remodeling at baseline is associated with poor improvement after CRT. (onlinejacc.org)
  • Kidney function was assessed by estimated glomerular filtration rate (eGFR) calculated using the Modification of Diet in Renal Disease equation, and the presence of proteinuria was measured by a urine dipstick. (clotcare.com)
  • Adherence to the Mediterranean diet is associated with positive renal function in healthy adults. (greenmedinfo.com)
  • 117.3) μmol/L. The discrepancy between renal function categories assessed using GFR MDRD and GFR CKD-EPI when compared with CrCl was observed in 23.4% and 27.6% of the cases, respectively. (clinpharm-journal.ru)
  • Atrial receptors and renal function. (springer.com)
  • No significant difference was present in S-Sr, A-Sr or global atrial strain between the normal and HT cohorts. (bmj.com)
  • Left atrial (LA) function by volume and strain analysis in children has been little studied. (ahajournals.org)
  • Right atrial peak strain derived from 2D-STE has been proved to be a reliable tool to study RA performance. (elsevier.pt)
  • 16 Peak atrial strain (the peak of the positive deflection occurring during the reservoir phase, when the right ventricle contracts and the right atrium fills against a closed tricuspid valve) is perhaps the most used parameter of RA function. (elsevier.pt)
  • RA volume 18 - for the same amount of blood received, dilated atria have lower peak atrial strain than non-dilated atria ( Figure 3 ). (elsevier.pt)
  • In accordance with the above, since a chronic significant left-to-right shunt through an ASD leads to a varying degree of RA dilatation due to volume overload, peak atrial strain should be decreased in ASD patients, who have dilated atria. (elsevier.pt)
  • Correlations between right atrial longitudinal strain and other echocardiographic parameters in patients with atrial septal defect. (revportcardiol.org)
  • Conclusions- Use of CPB was not associated with changes in cognitive function in our subjects who underwent repair of an ASD. (ahajournals.org)
  • The contribution of CPB to changes in cognitive function in children could be more precisely defined if preoperative and postoperative measures of cognitive function were available, as is often the case for adult patients. (ahajournals.org)
  • Furthermore, selection of a suitable comparison group of children matched for the multitude of factors that contribute to cognitive function is imperfect, as is post hoc statistical adjustment. (ahajournals.org)
  • We therefore performed a prospective observational study in which we evaluated cognitive function in subjects both before and after surgical repair of an atrial septal defect. (ahajournals.org)
  • Atrial fibrillation (AF) causes a impairment in cognitive function (CF) due to fluctuations in cardiac output and the decline of cerebral blood flow. (ovid.com)
  • Dietary Patterns Associated with Cognitive Function among the Older People in Underdeveloped Regions: Finding from the NCDFaC Study. (duke.edu)
  • Although dietary patterns are crucial to cognitive function, associations of dietary patterns with cognitive function have not yet been fully understood. (duke.edu)
  • These LA functions mechanically facilitate the transition between flow through the pulmonary venous circulation and the intermittent filling of the left ventricle [ 6 , 7 ]. (kjim.org)
  • There is increasing evidence that atrial fibrillation is associated with an increased risk of asymptomatic or silent cerebral infarction and as a result may confer an increased risk of progressive cognitive impairment on a person. (tcd.ie)
  • Atrial fibrillation (AF) has been linked with an increased risk for cognitive impairment and dementia in numerous studies over the past 2 decades. (medpagetoday.com)