Echocardiography, Doppler
Atrial Fibrillation
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Echocardiography, Doppler, Pulsed
Electric Countershock
Pericardiectomy
Echocardiography
Echocardiography, Transesophageal
Ventricular Function, Left
Observer Variation
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Stroke Volume
Blood Flow Velocity
Hemodynamics
Ventricular Function, Right
Human Rights
Ventricular Dysfunction, Right
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
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Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.
Publishing
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The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
Internet
Regional differences in the recovery course of tachycardia-induced changes of atrial electrophysiological properties. (1/150)
BACKGROUND: Regional differences in recovery of tachycardia-induced changes of atrial electrophysiological properties have not been well studied. METHODS AND RESULTS: In the control group (5 dogs), atrial effective refractory period (AERP) and inducibility of atrial fibrillation (AF) were assessed before and every 4 hours for 48 hours after complete atrioventricular junction (AVJ) ablation with 8-week VVI pacing. In experimental group 1 (15 dogs), AERP and inducibility of AF were assessed before and after complete AVJ ablation with 8-week rapid right atrial (RA) pacing (780 bpm) and VVI pacing. In experimental group 2 (7 dogs), AERP and inducibility of AF were assessed before and after 8-week rapid left atrial (LA) pacing and VVI pacing. AERP and inducibility and duration of AF were obtained from 7 epicardial sites. In the control group, atrial electrophysiological properties obtained immediately and during 48-hour measurements after pacing did not show any change. In the 2 experimental groups, recovery of atrial electrophysiological properties included a progressive recovery of AERP shortening, recovery of AERP maladaptation, and decrease of duration and episodes of reinduced AF. However, recovery of shortening and maladaptation of AERP and inducibility of AF was slower at the LA than at the RA and Bachmann's bundle. CONCLUSIONS: The LA had a slower recovery of tachycardia-induced changes of atrial electrophysiological properties, and this might play a critical role in initiation of AF. (+info)Influence of right atrial pressure on the cardiac pacemaker response to vagal stimulation. (2/150)
We have recently shown that the intrinsic rate response to an increase in right atrial pressure is augmented when cardiac muscarinic receptors are activated. This present study examines the cardiac pacemaker response to vagal stimulation at different values of right atrial pressure in isolated rat right atrium and in the rabbit heart in situ. In the rat atrium, when pressure was raised in steps from 2 to 10 mmHg, there was a progressive reduction in the response to vagal stimulation [40.5 +/- 7.2% reduction (mean +/- SE) at 8 mmHg, P < 0.01], which was independent of the level of vagal bradycardia, that persisted in the presence of the beta-adrenergic agonist isoproterenol. In barbiturate-anesthetized rabbits with cervical vagi cut and beta-adrenergic blockade, raising right atrial pressure approximately 2.5 mmHg by blood volume expansion reduced the bradycardia elicited by electrical stimulation of the peripheral end of the right vagus nerve (9.1 +/- 1.1% reduction, P < 0.0001). These results demonstrate that vagal bradycardia is modulated by the level of right atrial pressure and suggest that normally right atrial pressure may interact with cardiac vagal activity in the control of heart rate. (+info)Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. (3/150)
Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined. An intraduodenal administration of SRBT (1 g/kg) prevented theophylline (5 mg/kg, i.v.)-induced tachycardia in rats. SRBT also attenuated an increase in arterial blood pressure with a slow reduction in heart rate of rats treated with theophylline, with no influence on the plasma level of theophylline. However, SRBT did not change the beating rate of right atrium isolated from rats in the absence or presence of theophylline or isoproterenol. The locomotor activity of theophylline in mice was reduced by the treatment with SRBT. Furthermore, the latency of convulsions in mice induced by administration of theophylline at a higher dose (240 mg/kg, i.p.) was prolonged by treatment with SRBT (1 g/kg, p.o.) and seven out of fifteen mice were saved from death due to convulsions. These results suggest that theophylline-induced tachycardia and central nervous stimulation are suppressed by SRBT and that SRBT may reduce the undesirable actions of theophylline on the cardiovascular and central nervous systems. (+info)Rate-dependent conduction block of the crista terminalis in patients with typical atrial flutter: influence on evaluation of cavotricuspid isthmus conduction block. (4/150)
BACKGROUND: The crista terminalis (CT) has been identified as the posterior boundary of typical atrial flutter (AFL) in the lateral wall (LW) of the right atrium (RA). To study conduction properties across the CT, rapid pacing was performed at both sides of the CT after bidirectional conduction block was achieved in the cavotricuspid isthmus by radiofrequency catheter ablation. METHODS AND RESULTS: In 22 patients (aged 61+/-7 years) with AFL (cycle length, 234+/-23 ms), CT was identified during AFL by double electrograms recorded between the LW and posterior wall (PW). After the ablation procedure, decremental pacing trains were delivered from 600 ms to 2-to-1 local capture at the LW and PW or coronary sinus ostium (CSO). At least 5 bipolar electrograms were recorded along the CT from the high to the low atrium next to the inferior vena cava. No double electrograms were recorded during sinus rhythm in that area. Complete transversal conduction block all along the CT (detected by the appearance of double electrograms at all recording sites and craniocaudal activation sequence on the side opposite to the pacing site) was observed in all patients during pacing from the PW or CSO (cycle length, 334+/-136 ms), but it was fixed in only 4 patients. During pacing from the LW, complete block appeared at a shorter pacing cycle length (281+/-125 ms; P<0.01) and was fixed in 2 patients. In 3 patients, complete block was not achieved. CONCLUSIONS: These data suggest the presence of rate-dependent transversal conduction block at the crista terminalis in patients with typical AFL. Block is usually observed at longer pacing cycle lengths with PW pacing than with LW pacing. This difference may be a critical determinant of the counterclockwise rotation of typical AFL. (+info)Free-floating thrombi in the right heart: diagnosis, management, and prognostic indexes in 38 consecutive patients. (5/150)
BACKGROUND: Floating right heart thrombi (FRHTS) are a rare phenomenon, encountered almost exclusively in patients with suspected or proven pulmonary embolism and diagnosed by transthoracic echocardiography. Their management remains controversial. METHODS AND RESULTS: We report on a series of 38 consecutive patients encountered over the past 12 years. Thirty-two patients were in NYHA class IV, 20 in cardiogenic shock. Echocardiography usually demonstrated signs of cor pulmonale: right ventricular overload (91.7% of the population), paradoxical interventricular septal motion (75%), and pulmonary hypertension (86. 1%). The thrombus was typically wormlike (36 of 38 patients). It extended from the left atrium through a patent foramen ovale in 4 patients. Pulmonary embolism was confirmed in all but 1. Mortality was high (17 of 38 patients) irrespective of the therapeutic option chosen: surgery (8 of 17), thrombolytics (2 of 9), heparin (5 of 8), or interventional percutaneous techniques (2 of 4). The in-hospital mortality rate was significantly linked with the occurrence of cardiac arrest. Conversely, the outcome after discharge was usually good, because 18 of 21 patients were still alive 47.2 months later (range, 1 to 70 months). CONCLUSIONS: Severe pulmonary embolism was the rule in our series of FRHTS (mortality rate, 44.7%). The choice of therapy had no effect on mortality. Emergency surgery is usually advocated. However, thrombolysis is a faster, readily available treatment and seems promising either as the only treatment or as a bridge to surgery. In patients with contraindications to surgery or lytic therapy, interventional techniques may be proposed. (+info)Short-term effect of atrial fibrillation on atrial contractile function in humans. (6/150)
BACKGROUND: Conversion of chronic atrial fibrillation (AF) is associated with atrial stunning, but the short-term effect of a brief episode of AF on left atrial appendage (LAA) emptying velocity is unknown. The purpose of this study was to determine whether a short episode of AF affects left atrial function and whether verapamil modifies this effect. METHODS AND RESULTS: The subjects of this study were 19 patients without structural heart disease undergoing an electrophysiology procedure. In 13 patients, LAA emptying velocity was measured by transesophageal echocardiography in the setting of pharmacological autonomic blockade before, during, and after a short episode of AF. During sinus rhythm, the baseline LAA emptying velocity was measured 5 times and averaged. AF was then induced by rapid right atrial pacing. After either spontaneous or electrical conversion, LAA emptying velocity was measured immediately on resumption of sinus rhythm and every minute thereafter. The mean duration of AF was 15.3+/-3.8 minutes. The mean baseline emptying velocity was 70+/-20 cm/s. The first post-AF emptying velocity was 63+/-20 cm/s (P=0.02 versus baseline emptying velocity). The post-AF emptying velocity returned to the baseline emptying velocity value after 3.0 minutes. The mean percent reduction in post-AF emptying velocity was 9.7+/-21% (range, 15% increase to 56% decrease). A second group of 6 patients were pretreated with verapamil (0.1-mg/kg IV bolus followed by an infusion of 0.005 mg. kg-1. min-1). In these patients, the first post-AF emptying velocity, 58+/-14 cm/s, was not significantly different from the pre-AF emptying velocity, 60+/-13 cm/s (P=0.08). CONCLUSIONS: In humans, several minutes of AF may be sufficient to induce atrial contractile dysfunction after cardioversion. When atrial contractile dysfunction occurs, there is recovery of AF within several minutes. AF-induced contractile dysfunction is attenuated by verapamil and may be at least partially mediated by cellular calcium overload. (+info)Functional studies in atrium overexpressing A1-adenosine receptors. (7/150)
1. Adenosine and the A1-adenosine receptor agonist R-PIA, exerted a negative inotropic effect in isolated, electrically driven left atria of wild-type mice. 2. In left atria of mice overexpressing the A1-adenosine receptor, adenosine and R-PIA exerted a positive inotropic effect. 3. The positive inotropic effect of adenosine and R-PIA in transgenic atria could be blocked by the A1-adenosine receptor antagonist DPCPX. 4. In the presence of isoprenaline, adenosine exerted a negative inotropic effect in wild-type atria but a positive inotropic effect in atria from A1-adenosine receptor overexpressing mice. 5. The rate of beating in right atria was lower in mice overexpressing A1-adenosine receptors compared with wild-type. 6. Adenosine exerted comparable negative chronotropic effects in right atria from both A1-adenosine receptor overexpressing and wild-type mice. 7. A1-adenosine receptor overexpression in the mouse heart can reverse the inotropic but not the chronotropic effects of adenosine, implying different receptor-effector coupling mechanisms. (+info)Calf blood flow during prolonged tilt in idiopathic dilated cardiomyopathy and after cardiac transplantation. (8/150)
In severe congestive heart failure (CHF), abnormal reflex control of calf blood flow during brief head-up tilt that appears to normalize after transplantation (HTX) may be present during prolonged observation also. Therefore, we studied the effect of prolonged (30 min) 50 degrees head-up tilt on calf skeletal muscle blood flow measured by the local (133)Xe washout method in CHF and after HTX and in patients with the presence vs. absence of native right atrium (+PNA and -PNA, respectively). During brief head-up tilt, skeletal muscle blood flow increased 13 +/- 42% in 9 severe CHF patients in contrast to a -28 +/- 22% decrease (P < 0.01) in 11 control subjects, -24 +/- 30% decrease in 15 moderate CHF patients (P < 0.05), -25 +/- 14% decrease in 12 patients with recent HTX (P < 0.01), and -21 +/- 24% decrease in 8 patients with distant HTX (P = 0.06). However, during sustained tilt, blood flow declined to similar levels of that in the other groups in severe CHF. HTX -PNA vs. +PNA showed blunted skeletal muscle vasomotor control (P < 0.05) and a higher systolic blood pressure (139 +/- 14 vs. 125 +/- 15 mmHg, P < 0.05) and heart rate (92 +/- 10 vs. 83 +/- 8 beats/min, P < 0.05). Thus paradox vasodilatation of calf skeletal muscle in severe CHF is present only during brief but not prolonged tilt. This may be one explanation of the rare presence of orthostatic intolerance in CHF and implies only a minor possible role for the abnormality in edema pathogenesis. Removal of all right atrium in HTX has an important hemodynamic impact that may possibly affect later clinical outcome. (+info)Atrial function, left refers to the ability of the left atrium to effectively contract and pump blood into the left ventricle.
In the medical field, "Atrial Function, Left" refers to the ability of the left atrium, one of the two upper chambers of the heart, to effectively contract and pump blood into the left ventricle. This is an important aspect of cardiac function, as the left atrium plays a crucial role in the circulation of blood throughout the body. Atrial function can be assessed through various imaging techniques, such as echocardiography or magnetic resonance imaging (MRI). Abnormalities in left atrial function can be associated with a variety of cardiovascular conditions, including atrial fibrillation, heart failure, and valvular heart disease. Therefore, evaluating left atrial function can provide important information for the diagnosis and management of these conditions.
Atrial function refers to the ability of the atria, the upper chambers of the heart, to effectively contract and pump blood into the ventricles.
Atrial function refers to the ability of the atria, the upper chambers of the heart, to effectively contract and pump blood into the ventricles, the lower chambers of the heart. This is an important aspect of cardiac function, as proper atrial function is necessary for efficient blood flow and overall heart health. There are several measures of atrial function, including: 1. Atrial electromechanical delay: This refers to the time it takes for electrical signals to travel from the sinoatrial node (the heart's natural pacemaker) to the atria and for the atria to contract. 2. Atrial volume: This refers to the amount of blood that is contained within the atria at any given time. 3. Atrial pressure: This refers to the force exerted by the atria on the ventricles during contraction. 4. Atrial compliance: This refers to the ability of the atria to expand and accommodate an increase in blood volume. Abnormalities in atrial function can be associated with a variety of cardiovascular conditions, including heart failure, atrial fibrillation, and valvular heart disease. Assessment of atrial function is often performed using echocardiography, a non-invasive imaging technique that allows for visualization of the heart's structure and function.
Atrial function, right refers to the ability of the right atrium to effectively contract and pump blood into the right ventricle.
In the medical field, "Atrial Function, Right" refers to the ability of the right atrium, one of the two upper chambers of the heart, to effectively contract and pump blood into the right ventricle. This process is an important part of the heart's overall function and helps to ensure that oxygen-rich blood is delivered to the lungs and oxygen-poor blood is returned to the heart to be pumped to the rest of the body. Atrial function can be assessed through various diagnostic tests, including echocardiography, which uses sound waves to create images of the heart. Abnormalities in right atrial function can be associated with a variety of cardiovascular conditions, including heart failure, atrial fibrillation, and valvular heart disease.
Atrial Fibrillation is a type of irregular and rapid heartbeat that originates in the atria (upper chambers) of the heart.
Atrial fibrillation (AFib) is a type of arrhythmia, or abnormal heart rhythm, that occurs when the upper chambers of the heart (the atria) beat irregularly and rapidly, often out of sync with the lower chambers (the ventricles). This can cause the heart to pump inefficiently and can lead to blood clots, stroke, and other complications. AFib is a common condition, affecting an estimated 2.7 to 6.1 million people in the United States. It is more common in older adults and can be caused by a variety of factors, including high blood pressure, heart disease, and certain medical conditions. Treatment for AFib may include medications, lifestyle changes, and procedures to restore a normal heart rhythm.
Blood flow velocity is the speed at which blood flows through a blood vessel or artery.
Blood flow velocity refers to the speed at which blood flows through a blood vessel or artery. It is typically measured in units of meters per second (m/s) or centimeters per second (cm/s). Blood flow velocity is an important parameter in the assessment of cardiovascular health, as it can provide information about the functioning of the heart, blood vessels, and blood circulation. Blood flow velocity can be measured using various techniques, including Doppler ultrasound, magnetic resonance imaging (MRI), and computed tomography (CT) angiography. These techniques use sound waves or electromagnetic signals to detect the movement of blood through the blood vessels and calculate the velocity of blood flow. Abnormal blood flow velocities can indicate a variety of cardiovascular conditions, such as stenosis (narrowing) of the blood vessels, atherosclerosis (hardening of the arteries), and blood clots. Therefore, measuring blood flow velocity is an important diagnostic tool in the evaluation and management of cardiovascular diseases.
Ventricular dysfunction, right refers to the impaired ability of the right ventricle of the heart to pump blood effectively.
Ventricular dysfunction, right refers to a medical condition where the right ventricle of the heart is not functioning properly. The right ventricle is responsible for pumping blood from the heart to the lungs, where it receives oxygen and gets rid of carbon dioxide. When the right ventricle is not functioning properly, it can lead to a decrease in the amount of blood that is pumped to the lungs, which can cause a variety of symptoms and complications. There are several different causes of right ventricular dysfunction, including heart valve problems, heart muscle damage, and heart rhythm disorders. Treatment for right ventricular dysfunction depends on the underlying cause and may include medications, lifestyle changes, and in some cases, surgery. It is important to seek medical attention if you are experiencing symptoms of right ventricular dysfunction, as early diagnosis and treatment can help to improve outcomes and prevent complications.
Access to Information in the medical field refers to the ability of patients and healthcare providers to obtain and understand medical information, including their own health records and relevant medical research.
In the medical field, "Access to Information" refers to the ability of patients, healthcare providers, and other authorized individuals to obtain and understand the medical information they need to make informed decisions about their health and care. This includes information about a patient's medical history, current condition, treatment options, and potential risks and benefits of various medical interventions. Access to information is critical in the medical field because it enables patients to participate actively in their own care, make informed decisions about their treatment options, and monitor their health status. It also helps healthcare providers to provide more effective and personalized care by enabling them to access and analyze patient data more efficiently and accurately. Access to information can be facilitated through a variety of means, including electronic health records (EHRs), patient portals, and other digital tools. These tools can help to streamline the process of sharing medical information between healthcare providers and patients, and can also help to ensure that patients have access to the information they need to make informed decisions about their health and care.
Silent brain infarcts impact on cognitive function in atrial fibrillation
... Eur Heart J. 2022 Jun 6;43(22):2127-2135. doi: ... Aims: We aimed to investigate the association of clinically overt and silent brain lesions with cognitive function in atrial ... Keywords: Atrial fibrillation; Brain infarction; Cognitive function; Magnetic resonance imaging; Oral anticoagulation. ...
Medical Science Monitor | Left atrial function in patients with renal transplantation - Article abstract #510707
Atrial function was evaluated in M-mode and 2D projections and by cross-sectional Doppler echocardiography. The results ... The aim of our study was to evaluate left atrial function in patients after renal transplantation and compare them with ... total left atrial fraction (FClp), or IElp ratio.Conclusion: Abnormal function of the left atrium in the course of uremia ... In both investigated groups there were no differences in minimal left atrial dimensions (LAmin), PEPlp/Etlp ratio, P wave time ...
The Impact of Body Weight and Renal Function on the Risk of Bleeding With Direct Oral Anticoagulants in Atrial Fibrillation. -...
Atrial fibrillation (AF) increases the risk of stroke and direct oral anticoagulants (DOACs) are first-line agents for ... DOACs for patients with renal dysfunction and/or extremes in body weight.To evaluate the impact body weight and renal function ... The Impact of Body Weight and Renal Function on the Risk of Bleeding With Direct Oral Anticoagulants in Atrial Fibrillation.. ... This retrospective cohort study included adults with nonvalvular atrial fibrillation (NVAF) or atrial flutter (AFL) receiving a ...
Atrial Fibrillation - Introduction, Symptoms, Types, Functions and Reasons
The main function of the ventricle to deliver enough blood to the body for their regular and normal functioning. And the blood ... Types of Atrial Fibrillation. On the basis of different research and studies, atrial fibrillation are classified into different ... Symptoms of Atrial Fibrillation. Person who is atrial fibrillation shows various different symptoms. Some of the common ... Reason behind Atrial Fibrillation. Major factors which work behind atrial fibrillation is abnormal heart beat. As during ...
Influence of diastolic mechanics on cardiac electrophysiology: effects on sino-atrial node function - Department of Physiology,...
Relation of atrial natriuretic pepitdes to left ventricular systolic and diastolic function in heart failure<...
Relation of atrial natriuretic pepitdes to left ventricular systolic and diastolic function in heart failure. In: European ... Relation of atrial natriuretic pepitdes to left ventricular systolic and diastolic function in heart failure. European Journal ... Relation of atrial natriuretic pepitdes to left ventricular systolic and diastolic function in heart failure. / Wijbenga, JAM ( ... title = "Relation of atrial natriuretic pepitdes to left ventricular systolic and diastolic function in heart failure", ...
Assessment of left atrial functions in cardiac syndrome X | AVESÄ°S
Atrial Septal Defect: Background, Pathophysiology, Etiology
Atrial septal defect is characterized by a defect in the interatrial septum allowing pulmonary venous return from the left ... Atrial septal defect (ASD) is one of the more commonly recognized congenital cardiac anomalies presenting in adulthood. ... Atrial function after surgical and percutaneous closure of atrial septal defect: a strain rate imaging study. J Am Soc ... left atrial pressure may exceed right atrial pressure by several millimeters of mercury, whereas with large ASD, mean atrial ...
ESC 365 - Left ventricular diastolic function is a determinant of the left atrial mechanics in systemic sclerosis
Left ventricular diastolic function is a determinant of the left atrial mechanics in systemic sclerosis. ... The association between Doppler indices of left ventricular diastolic function and left atrial volume by cardiac magnetic ... Assessment of left ventricular systolic function and torsion at 3 myocardial layers in hypertension by real-time three- ...
Improvement in renal and endothelial function after catheter ablation in patients with persistent atrial fibrillation<...
keywords = "Catheter ablation, Endothelial function, Paroxysmal atrial fibrillation, Persistent atrial fibrillation, Renal ... Improvement in renal and endothelial function after catheter ablation in patients with persistent atrial fibrillation. Journal ... Improvement in renal and endothelial function after catheter ablation in patients with persistent atrial fibrillation. In: ... Improvement in renal and endothelial function after catheter ablation in patients with persistent atrial fibrillation. / Okawa ...
Left atrial function assessed by left atrial strain in patients with left circumflex branch culprit acute myocardial infarction...
Left atrial function assessed by left atrial strain in patients with left circumflex branch culprit acute myocardial infarction ... Echocardiography was performed to evaluate left ventricular diastolic function, LA volume, and LA function. Systolic (LAS ) and ... We hypothesized that LA function would be further decreased in AMI patients with a culprit lesion in the left circumflex branch ... The lower global LAS strain might suggest decreased LA function resulting from ischemic insult by AMI with culprit lesions in ...
Structure and Function of the Left Atrium and Left Atrial Appendage: AF and Stroke Implications<...
Structure and Function of the Left Atrium and Left Atrial Appendage: AF and Stroke Implications. Journal of the American ... Structure and Function of the Left Atrium and Left Atrial Appendage : AF and Stroke Implications. In: Journal of the American ... Structure and Function of the Left Atrium and Left Atrial Appendage: AF and Stroke Implications. / Delgado, Victoria; Di Biase ... title = "Structure and Function of the Left Atrium and Left Atrial Appendage: AF and Stroke Implications", ...
3D modelling of atrial and ventricular shape and function in a patient following the new modified Mustard operation | QScience...
3D modelling of atrial and ventricular shape and function in a patient following the new modified Mustard operation, Page 1 of ... 3D modelling of atrial and ventricular shape and function in a patient following the new modified Mustard operation ... oa 3D modelling of atrial and ventricular shape and function in a patient following the new modified Mustard operation ... Comparison of long-term outcomes of atrial repair of simple transposition with implications for a late arterial switch strategy ...
Novel molecular targets for atrial fibrillation therapy | Nature Reviews Drug Discovery
Atrial fibrillation is the most common type of cardiac arrhythmia, and is responsible for substantial morbidity and mortality ... This Review focuses on the mechanistic rationale for the development of new anti-atrial fibrillation drugs, on the molecular ... Dobrev and colleagues discuss the rationale for developing new anti-atrial fibrillation drugs, the molecular and structural ... efforts have been invested in developing novel treatments that target the underlying molecular determinants of atrial ...
Pediatric Holt-Oram Syndrome Treatment & Management: Medical Care, Surgical Care, Long-Term Monitoring
TBX5 loss-of-function mutation contributes to atrial fibrillation and atypical Holt-Oram syndrome. Mol Med Rep. 2016 May. 13(5 ... A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation. Circ Res. ... Developmental structure-function insights from Tbx5(del/+) mouse model of Holt-Oram syndrome. Am J Physiol Heart Circ Physiol. ... Atrial fibrillation and other clinical manifestations of altered TBX5 dosage in typical Holt-Oram syndrome. Circ Res. 2008 Sep ...
Stanley Jere - Articles - Scientific Research Publishing
Aboeata, Ahmed S | Creighton University
Outcomes of percutaneous left atrial appendage occlusion on left atrial function: a systematic review and meta-analysis. Raahat ... Augmentation of left ventricular systolic function with intravenous microbubbules and intermittent high mechanical index ... High Mechanical Index Impulses on Global Longitudinal Strain in patients with normal versus abnormal systolic function. ...
What Is Atrial Flutter?
What Is Atrial Flutter - The heart comprises two upper chambers called left and right atria, two lower chambers, and left and ... This faster heart rate causes the heart not to function at its best, leading to various other health conditions, including ... Atrial Flutter Symptoms. People may have no atrial flutter symptoms. The increment in atrial flutter rate can cause stroke, ... Understanding Atrial Flutter. The atrial flutter is when your upper chamber is beating too quickly. It is a heart rhythm ...
SCN5A gene: MedlinePlus Genetics
This condition affects the function of the sino-atrial (SA) node, which is an area of specialized cells in the heart that ... Familial atrial fibrillation. MedlinePlus Genetics provides information about Familial atrial fibrillation. More About This ... Normal Function. The SCN5A gene belongs to a family of genes that provide instructions for making sodium channels. These ... Gui J, Wang T, Jones RP, Trump D, Zimmer T, Lei M. Multiple loss-of-function mechanisms contribute to SCN5A-related familial ...
Pediatric Holt-Oram Syndrome: Background, Pathophysiology, Epidemiology
TBX5 loss-of-function mutation contributes to atrial fibrillation and atypical Holt-Oram syndrome. Mol Med Rep. 2016 May. 13(5 ... A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation. Circ Res. ... in that it is associated with a gain-of-function mechanism and is associated with paroxysmal atrial fibrillation and no ... ASD = Atrial septal defect; RA = Right atrium; RV = Right ventricle; LA = Left atrium; LV = Left ventricle. View Media Gallery ...
Paradigm-Challenging HF Treatment Hopeful in Early Trial
Nutrients | Free Full-Text | Elevated Plasma Vitamin B12 Concentrations Are Independent Predictors of In-Hospital Mortality in...
... renal function, C-reactive protein and prealbumin. Patients with high vitamin B12 also had a longer length of stay (LOS) than ... Impaired renal function is associated with recurrence after cryoballoon catheter ablation for paroxysmal atrial fibrillation: A ... renal function, C-reactive protein and prealbumin. Patients with high vitamin B12 also had a longer length of stay (LOS) than ... renal function and prealbumin (Table 3). This significant independent association was also confirmed in those models ...
prof. dr. P.A.F.M. (Pieter A.) Doevendans - UMC Utrecht
The work was completed in Maastricht and provided the basis for a thesis on the function of the promoter of the atrial Myosin ... The work was completed in Maastricht and provided the basis for a thesis on the function of the promoter of the atrial Myosin ... The Netherlands Heart Foundation: "Characterization of the effects of estrogen on cardiac function under pathophysiologic ... "The characterization of the regulatory sequence of the atrial myosin light chain 2 gene". ...
Common Features of Cardiac and Respiratory Disease: A Diagnostic Conundrum - WSAVA2008 - VIN
Echocardiography can also be used to identify changes in left atrial size, as well as overall assessment of cardiac function. ... This inter-relationship is crucial to normal body function as it is the method by which O2 is delivered to the body tissues and ... Why this difference in species occurs is not known, but it probably reflects differences in left atrial compression of the left ... The transmission of the raised left atrial pressures associated with heart failure to the pulmonary veins eventually results in ...
SPAF 2019 review | Thrombosis Adviser
Renal function considerations for stroke prevention in atrial fibrillation. Am J Med. 2017;130(9):1015-23. Return to content ... Worsening of renal function in atrial fibrillation patients with stage 3 or 4 chronic kidney disease treated with warfarin or ... Preserving kidney function in patients with atrial fibrillation: What do the new data say? ... Preserving kidney function in patients with atrial fibrillation: What do the new data say? ...
Treatment of Atrial Fibrillation | Effective Health Care (EHC) Program
Background and Objectives for the Systematic Review Definition and Impact of Atrial Fibrillation Atrial fibrillation (AF) is a ... left atrial dimension, left atrial appendage flow, and left ventricular function-have been examined as potential risk variables ... left atrial dimension, left atrial appendage flow, and left ventricular function-have been examined as potential risk variables ... AF atrial fibrillation AFFIRM Atrial Fibrillation Follow-up Investigation of Rhythm Management AHA American Heart Association ...
Dilatation | Profiles RNS
Percutaneous Balloon Mitral Valvuloplasty | IntechOpen
... atrial size, left and right ventricular functions, and pulmonary arterial pressure. Transesophageal echocardiography (TEE) is ... Atrial septal defect. A wide range of frequency has been reported (10-90%) depending on modality that has been used for ... Prognostic significance of atrial fibrillation and severity of symptoms of heart failure in patients with low gradient aortic ... Atrial septal defect after percutaneous mitral balloon valvuloplasty: immediate results and follow-up.. Journal of the American ...
Anticoagulation for atrial fibrillation-trends in the United States
The use of anticoagulation therapy for atrial fibrillation has slowly increased in the last decade, yet many patients at ... Thyroid Function Could Help Predict NAFLD Risk in Diabetes. September 18th 2023 ... Anticoagulation for atrial fibrillation-trends in the United States. Sep 8, 2008. Robert J. Anderson, MD: From the Department ... Results of our study showed that there has been an increase in the use of anticoagulant agents for patients with atrial ...
Associate Professor Min Jun
... and Kidney Function: Comparative Effectiveness and Safety of Warfarin in Older Adults With Newly Diagnosed Atrial Fibrillation ... 2015, The association between kidney function and major bleeding in older adults with atrial fibrillation starting warfarin ... warfarin in adults with atrial fibrillation: a multicenter observational study, EUROPEAN HEART JOURNAL-QUALITY OF CARE AND ... Turin TC; Jun M; James MT; Tonelli M; Coresh J; Manns BJ; Hemmelgarn BR, 2016, Magnitude of rate of change in kidney function ...
Paroxysmal atrial fibriNonvalvular atrial fibrillationVentricularSeptal defectFibrillation includeComplicationsCatheter AblationPatientsContractionDiastolicFlutterSystolicStrokeSymptomsArrhythmiasEndothelialClinical2017ThrombusCognitiveLeftAbnormalIrregular heartRenal functionHypertensionIschemicMethodsChaoticFindingsAtypicalDefectsPulmonaryHeartRiskCommonAnatomy
Paroxysmal atrial fibri2
- A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation. (medscape.com)
- this is a novel mutation, in that it is associated with a gain-of-function mechanism and is associated with paroxysmal atrial fibrillation and no structural heart disease. (medscape.com)
Nonvalvular atrial fibrillation1
- This retrospective cohort study included adults with nonvalvular atrial fibrillation (NVAF) or atrial flutter (AFL) receiving a DOAC ≥12 months. (physiciansweekly.com)
Ventricular7
- OBJECTIVE: Cardiac syndrome X (CSX) affects left ventricular functions due to myocardial ischaemia. (comu.edu.tr)
- Echocardiography was performed to evaluate left ventricular diastolic function, LA volume, and LA function. (bvsalud.org)
- Researchers see transvenous ablation of the right greater splanchnic nerve (GSN) as potentially appropriate for patients with HF, regardless of ventricular function or acuity. (medscape.com)
- Other causes of coronary embolism include atrial fibrillation, left atrial tumours, bacterial endocarditis, atrial and ventricular mural thrombus, syphilis and pulmonary vein thrombosis [7]. (who.int)
- In atrial fibrillation, the atria do not contract, and the atrioventricular (AV) conduction system is bombarded with many electrical stimuli, causing inconsistent impulse transmission and an irregularly irregular ventricular rate, which is usually in the tachycardia rate range. (msdmanuals.com)
- The aim of the study was to evaluate the left atrial and ventricular geometry, systolic and diastolic functions in patients with CLD. (bvsalud.org)
- However, left ventricular diastolic dysfunction, left atrial enlargement, and increased left ventricular mass index (LVMI) were more prevalent among the patients with CLD compared to controls (P (bvsalud.org)
Septal defect4
- Atrial septal defect (ASD) is one of the more commonly recognized congenital cardiac anomalies presenting in adulthood. (medscape.com)
- The magnitude of the left-to-right shunt across the atrial septal defect (ASD) depends on the defect size, the relative compliance of the ventricles, and the relative resistance in both the pulmonary and systemic circulation. (medscape.com)
- Atrial septal defect (ASD) is a congenital cardiac disorder caused by the spontaneous malformation of the interatrial septum. (medscape.com)
- A 2-dimensional echocardiographic picture taken from subxiphoid window showing a large secundum atrial septal defect (arrow) in a 7-year-old boy with Holt-Oram syndrome. (medscape.com)
Fibrillation include1
- I. Some of major Complications of atrial fibrillation include: heart failure and stroke. (vedantu.com)
Complications2
- The increment in atrial flutter rate can cause stroke, heart failure and damage, and other heart complications. (tutorialspoint.com)
- 2 Although the risk of ischemic stroke related to atrial fibrillation is significantly reduced with warfarin (Coumadin) treatment, anticoagulation treatment can possibly lead to an increased risk of complications from bleeding. (hcplive.com)
Catheter Ablation1
- Background: Cardiovascular events in patients with atrial fibrillation (AF) can be lowered by catheter ablation. (elsevierpure.com)
Patients22
- We aimed to investigate the association of clinically overt and silent brain lesions with cognitive function in atrial fibrillation (AF) patients. (nih.gov)
- To evaluate the impact body weight and renal function have on major and clinically relevant nonmajor (CRNM) bleeding events and ischemic strokes in AF patients receiving a DOAC. (physiciansweekly.com)
- In this study our aim was to determine the changes in left atrial functions in patients with CSX. (comu.edu.tr)
- In PeAF patients with CKD, an improved endothelial function after ablation was associated with an improved renal function. (elsevierpure.com)
- Left atrial function assessed by left atrial strain in patients with left circumflex branch culprit acute myocardial infarction. (bvsalud.org)
- We hypothesized that LA function would be further decreased in AMI patients with a culprit lesion in the left circumflex branch (LCX). (bvsalud.org)
- Pollicization to improve function of index finger is recommended for patients with aplasia of the thumb. (medscape.com)
- Prevalence and spectrum of TBX5 mutation in patients with lone atrial fibrillation. (medscape.com)
- The focus on careful management of patients with atrial fibrillation (AF) and co-morbidities, such as renal impairment and diabetes, has recently intensified. (thrombosisadviser.com)
- 2019 has seen an accumulation of real-world data on the efficacy and safety of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with AF who also have renal impairment and/or diabetes, as well as data on the effect of NOACs on preserving renal function in these patients. (thrombosisadviser.com)
- Several studies have investigated the effect of NOACs, in particular rivaroxaban, on renal outcomes in patients with AF, 1, 2, 6- 8 and a guideline update has been published acknowledging that the choice of anticoagulation can have an impact on renal function. (thrombosisadviser.com)
- Analyses from three studies suggested that some NOACs, in particular rivaroxaban, may reduce renal function worsening compared with vitamin K antagonists (VKAs) in patients with AF regardless of whether their renal function is already impaired. (thrombosisadviser.com)
- The 2011 Focused Update on the Management of Patients with Atrial Fibrillation-by the American College of Cardiology Foundation (ACCF), the AHA, and the Heart Rhythm Society (HRS)-addressed the issue of strict versus lenient rate control in patients with AF. (ahrq.gov)
- The use of anticoagulation therapy for atrial fibrillation has slowly increased in the last decade, yet many patients at relatively high risk for thromboembolic events are still not receiving anticoagulants. (hcplive.com)
- 3-5 To help guide the clinician in determining the degree of risk of thromboembolic events posed by atrial fibrillation in individual patients, 2 approaches have been employed. (hcplive.com)
- 4,6,7 The other strategy, which is usually applied more selectively, is the use of transthoracic and transesophageal echocardiography to help assess thromboembolic risk in patients with atrial fibrillation. (hcplive.com)
- 8-12 To determine current use of anticoagulation for patients with atrial fibrillation, we recently analyzed the National Ambulatory Medical Care Survey (NAMCS), a large ambulatory patient database, to determine the time trends in the use of anticoagulation therapy for the prevention of thromboembolism in patients with atrial fibrillation. (hcplive.com)
- We examined the 1994 through 2003 NAMCS database to establish the utilization patterns of anticoagulant therapy among patients diagnosed with atrial fibrillation. (hcplive.com)
- Over the course of the study period, approximately 40.5 million atrial fibrillation patient visits occurred, and 18.5 million (45.6%) of these patients received anticoagulant therapy. (hcplive.com)
- 03). Interestingly, the presence of one comorbid factor, diabetes mellitus, which has been shown to be associated with thromboembolism in patients with atrial fibrillation, was associated with a lower frequency of anticoagulation therapy (37% of patients with and 46% of patients without diabetes received anticoagulation therapy). (hcplive.com)
- Atrial fibrillation tends to occur in patients with an underlying heart disorder. (msdmanuals.com)
- Conclusion: The study demonstrated increased left atrial diameter, increased LVMI associated with diastolic dysfunction, and preserved systolic function at rest among CLD patients. (bvsalud.org)
Contraction1
- Likely some augmentation occurs during atrial contraction. (medscape.com)
Diastolic1
- C'est LAVi: What Left Atrial Dilatation Tells Us About Diastolic Function in Aortic Stenosis. (umassmed.edu)
Flutter11
- What Is Atrial Flutter? (tutorialspoint.com)
- The atrial flutter is when your upper chamber is beating too quickly. (tutorialspoint.com)
- Atrial flutter has an organized heart rhythm and is less chaotic, unlike atrial fibrillation, where the heartbeat pattern is irregular. (tutorialspoint.com)
- If a short circuit of the heart's electrical signal occurs, it causes atrial flutter. (tutorialspoint.com)
- People may have no atrial flutter symptoms. (tutorialspoint.com)
- Atrial flutter is an age-triggered arrhythmia. (tutorialspoint.com)
- The other common causes of atrial flutter are if you have gone through the following already. (tutorialspoint.com)
- If the heart causes atrial flutter to continue to pulsate for a long time, it can cause cardiomyopathy, which weakens the heart muscles. (tutorialspoint.com)
- Effective atrial flutter treatment involves medication or clinical procedures devised to scar small areas of heart tissue (ablation). (tutorialspoint.com)
- Doctors diagnose for any other health conditions causing the atrial flutter. (tutorialspoint.com)
- A non-surgical, catheter-based procedure can often heal atrial flutter. (tutorialspoint.com)
Systolic1
- Systolic function of the left ventricle was similar in the two arms. (bvsalud.org)
Stroke5
- Atrial fibrillation (AF) increases the risk of stroke and direct oral anticoagulants (DOACs) are first-line agents for prevention. (physiciansweekly.com)
- Atrial fibrillation (AF) and stroke are important major health problems that share common risk factors and frequently coexist. (elsevierpure.com)
- Left atrial (LA) remodeling is an important underlying substrate for AF and stroke. (elsevierpure.com)
- 1 An increased risk of embolic stroke is a major risk factor associated with the diagnosis of atrial fibrillation. (hcplive.com)
- Atrial thrombi may form, causing a significant risk of embolic stroke. (msdmanuals.com)
Symptoms1
- Person who is atrial fibrillation shows various different symptoms. (vedantu.com)
Arrhythmias2
- Depending on the size of the defect, size of the shunt, and associated anomalies, this can result in a spectrum of disease ranging from no significant cardiac sequelae to right-sided volume overload, pulmonary arterial hypertension, and even atrial arrhythmias. (medscape.com)
- Atrial fibrillation is one of the most common arrhythmias, affecting between 3 and 6 million adults in the US. (msdmanuals.com)
Endothelial1
- We hypothesized the underlying mechanism was improvement in renal and endothelial function corresponding to AF burden, and investigated whether restoration of sinus rhythm (SR) after ablation affected these functions according to AF type. (elsevierpure.com)
Clinical2
- This Review focuses on the mechanistic rationale for the development of new anti-atrial fibrillation drugs, on the molecular and structural motifs that they target and on the results obtained so far in experimental and clinical studies. (nature.com)
- Despite clinical criteria guidelines useful for predicting thromboembolic risk, previous studies have shown that anticoagulation therapy is underused in many high-risk populations with atrial fibrillation. (hcplive.com)
20171
- Cite this: Kidney Disease Is Linked to Higher Risk for Atrial Fibrillation - Medscape - Sep 06, 2017. (medscape.com)
Thrombus1
- However, in transoesophageal echocardiography, there was a semi-mobile thrombus on the left atrial surface of the valve measuring 5 × 5 mm ( Figure 2 ). (who.int)
Cognitive1
- Some cognitive decline can occur as adults age, but frequently forgetting how to perform routine tasks, for example, is not a normal part of aging and can affect a person's ability to live and function independently. (cdc.gov)
Left3
- Assessment of left atrial functions in c. (comu.edu.tr)
- With small ASD, left atrial pressure may exceed right atrial pressure by several millimeters of mercury, whereas with large ASD, mean atrial pressures are nearly identical. (medscape.com)
- Why this difference in species occurs is not known, but it probably reflects differences in left atrial compression of the left mainstem bronchus. (vin.com)
Abnormal1
- Major factors which work behind atrial fibrillation is abnormal heart beat. (vedantu.com)
Irregular heart1
- Also, there may be development of an irregular heart rhythm known as atrial fibrillation. (wikipedia.org)
Renal function2
- The Impact of Body Weight and Renal Function on the Risk of Bleeding With Direct Oral Anticoagulants in Atrial Fibrillation. (physiciansweekly.com)
- and preserving renal function. (thrombosisadviser.com)
Hypertension1
- Treatment began with IV unfractionated hepa- history of diabetes mellitus, arterial hypertension, rin (18 UI/kg/h), hydroxychloroquine (200 mg oral- coronary heart disease, peripheral arterial disease, ly 2×/d), and antimicrobial drugs (ceftriaxone 1g by and atrial fibrillation (treated with apixaban [2.5 mg IV infusion/d). (cdc.gov)
Ischemic1
- The lower global LAS strain might suggest decreased LA function resulting from ischemic insult by AMI with culprit lesions in the LCX. (bvsalud.org)
Methods1
- A vast majority of atrial septal defects may be closed by transcatheter methods. (medscape.com)
Chaotic1
- Atrial fibrillation has been attributed to multiple wavelets with chaotic reentry within the atria. (msdmanuals.com)
Findings1
- Laboratory findings revealed low leukocyte cardiovascular conditions, particularly atrial fibril- count and lymphopenia (Appendix, https://ww- lation, although both were adequately treated with wnc.cdc.gov/EID/article/26/9/20-1791-App1.pdf). (cdc.gov)
Atypical1
- TBX5 loss-of-function mutation contributes to atrial fibrillation and atypical Holt-Oram syndrome. (medscape.com)
Defects1
- Cachat F, Rapatsalahy A, Sekarski N, Hurni M, von Segesser L, Payot M. [Three different types of atrial septal defects in the same family]. (medscape.com)
Pulmonary1
- However, in many cases, firing of an ectopic focus within venous structures adjacent to the atria (usually the pulmonary veins) is responsible for initiation and perhaps maintenance of atrial fibrillation. (msdmanuals.com)
Heart6
- Condition when there is irregular or quivering in the heart beat, is called atrial fibrillation. (vedantu.com)
- One who is suffering from atrial fibrillation, then in them there is reduction in the ability of the atria to pump blood into the ventricles, which force the heart to beat too rapidly. (vedantu.com)
- Under this atrial fibrillation, there is continuation of irregular pattern of heart beat for more than 12 month. (vedantu.com)
- Prevention of atrial fibrillation: report from a National Heart, Lung, and Blood Institute workshop. (nature.com)
- A lower heart rate at rest implies the heart is functioning efficiently. (tutorialspoint.com)
- This condition affects the function of the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. (medlineplus.gov)
Risk1
- To address these questions and expand prior work in this area, our group recently published a meta-analysis of three diverse community-based cohorts with a broad range of kidney function to examine the associations of eGFR (calculated from serum creatinine and cystatin C) and UACR with risk for incident AF. (medscape.com)
Common3
- Atrial fibrillation (AF) is the most common form of cardiac arrhythmia. (nature.com)
- Atrial fibrillation is the most common type of cardiac arrhythmia, and is responsible for substantial morbidity and mortality in the general population. (nature.com)
- Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population, affecting more than 2 million adults in the United States. (medscape.com)
Anatomy1
- It is not surprising that an interaction exists between the cardiovascular and respiratory system as they are closely linked in terms of anatomy and function. (vin.com)
