Atrial Function, Left: The hemodynamic and electrophysiological action of the LEFT ATRIUM.Atrial Function: The hemodynamic and electrophysiological action of the HEART ATRIA.Atrial Function, Right: The hemodynamic and electrophysiological action of the RIGHT ATRIUM.Heart Atria: The chambers of the heart, to which the BLOOD returns from the circulation.Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.Echocardiography, Doppler, Pulsed: Echocardiography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.Pericardiectomy: Surgical excision (total or partial) of a portion of the pericardium. Pericardiotomy refers to incision of the pericardium.Electric Countershock: An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Heart Function Tests: Examinations used to diagnose and treat heart conditions.Echocardiography, Transesophageal: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.Ventricular Function: The hemodynamic and electrophysiological action of the HEART VENTRICLES.Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Observer Variation: The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.Echocardiography, Three-Dimensional: Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Aortic Valve Prolapse: The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).Hydroxymethylglutaryl-CoA Reductase Inhibitors: Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.ThiazepinesBlood Pressure Monitoring, Ambulatory: Method in which repeated blood pressure readings are made while the patient undergoes normal daily activities. It allows quantitative analysis of the high blood pressure load over time, can help distinguish between types of HYPERTENSION, and can assess the effectiveness of antihypertensive therapy.Atrial Appendage: Ear-shaped appendage of either atrium of the heart. (Dorland, 28th ed)Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.Ultrasonography, Doppler, Color: Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.Echocardiography, Doppler, Color: Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Personnel Staffing and Scheduling Information Systems: Computer-based systems for use in personnel management in a facility, e.g., distribution of caregivers with relation to patient needs.Heart: The hollow, muscular organ that maintains the circulation of the blood.New York CityNew YorkAmerican Heart Association: A voluntary organization concerned with the prevention and treatment of heart and vascular diseases.Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.Vectorcardiography: Recording of the moment-to-moment electromotive forces of the heart on a plane of the body surface delineated as a vector function of time.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Radiology Information Systems: Information systems, usually computer-assisted, designed to store, manipulate, and retrieve information for planning, organizing, directing, and controlling administrative activities associated with the provision and utilization of radiology services and facilities.Communication: The exchange or transmission of ideas, attitudes, or beliefs between individuals or groups.Bacteriology: The study of the structure, growth, function, genetics, and reproduction of bacteria, and BACTERIAL INFECTIONS.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Catheter Ablation: Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.Recurrence: The return of a sign, symptom, or disease after a remission.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Pulmonary Veins: The veins that return the oxygenated blood from the lungs to the left atrium of the heart.Retreatment: The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.Anti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Effects of pacing-induced and balloon coronary occlusion ischemia on left atrial function in patients with coronary artery disease. (1/343)

OBJECTIVES: The aim of this study was to compare left atrial (LA) function in 16 patients with distal left anterior descending (LAD) and in 16 patients with proximal left circumflex (LCx) coronary artery stenosis at rest and immediately after pacing-induced tachycardia (LAD-pacing [P] and LCx-P) or coronary occlusion (LAD-CO and LCx-CO). BACKGROUND: During left ventricular (LV) ischemia, compensatory augmentation of LA contraction enhances LV filling and performance. The left atrium is supplied predominantly by branches arising from the LCx. Therefore, we hypothesized that one mechanism for the loss of atrial contraction may be ischemic LA dysfunction. METHODS: Left ventricular and LA pressure-area relations were derived from simultaneous double-tip micromanometer pressure recordings and automatic boundary detection echocardiograms. RESULTS: Immediately after pacing or after coronary occlusion, LV end-diastolic pressure, LV relaxation, LA mean pressure and LV stiffness significantly increased in all patients. However, the area of the A loop of the LA pressure-area relation, representing the LA pump function, significantly decreased in groups LCx-P and LCx-CO (from 14+/-3 to 9+/-2, and from 16+/-4 to 9+/-2 mm Hg.cm2, respectively, p < 0.05), whereas it increased in groups LAD-P and LAD-CO (from 12+/-3 to 54+/-10, and from 16+/-3 to 49+/-8 mm Hg.cm2, respectively, p < 0.001). CONCLUSIONS: In patients with LAD stenosis, LV supply or demand ischemia is associated with enhanced LA pump function. However, in patients with proximal LCx stenosis who develop the same type and degree of ischemia, LA branches might have been affected, rendering the LA ischemic and unable to increase its booster pump function.  (+info)

Pulmonary venous flow in hypertrophic cardiomyopathy as assessed by the transoesophageal approach. The additive value of pulmonary venous flow and left atrial size variables in estimating the mitral inflow pattern in hypertrophic cardiomyopathy. (2/343)

AIMS: This study was conducted to assess the characteristics of the pattern of pulmonary venous flow and to document the interaction of this flow and left atrial function with the pattern of mitral inflow in hypertrophic cardiomyopathy. METHODS AND RESULTS: Pulmonary venous and mitral flows were evaluated by the transoesophageal approach in 80 patients with hypertrophic cardiomyopathy. Left atrial size and function were measured by the transthoracic approach. Their values were compared with those obtained from 35 normal controls. Twelve patients showed significant (> 2+) mitral regurgitation. As a group, hypertrophic cardiomyopathy patients showed increased atrial reversal flow and longer deceleration time of the diastolic wave, but a wide variability of pulmonary venous flow patterns were observed. Thirty patients (37.5%) had pseudonormal mitral flow patterns. Stepwise multilinear regression analysis identified the ratio of systolic to diastolic pulmonary venous flow velocity, the ratio of velocity-time integrals of both flow waves at atrial contraction, the left atrial minimal volume and the systolic fraction as independent predictive variables of the mitral E/A wave velocity ratio (r = 0.82). By logistic regression, the former three variables were selected as independent predictive covariates of a pseudonormal mitral flow pattern (sensitivity: 83%, specificity: 90%). The ratio of velocity-time integrals of both atrial waves was the most important predictive variable in both analyses. CONCLUSIONS: The observed variability in the configuration of pulmonary venous flow velocity waveform is related to what occurs in transmitral flow in patients with hypertrophic cardiomyopathy. Significant mitral regurgitation is not an independent correlate of pseudonormal mitral inflow patterns in these patients. Our results further emphasize the complementary, additive value of the pulmonary venous flow velocity pattern and left atrial size in the interpretation of the mitral flow velocity pattern, and indirectly suggest the underlying increased left ventricular filling pressures of patients with hypertrophic cardiomyopathy and pseudonormal mitral flow patterns.  (+info)

Doppler sonographic evaluation of left atrial function after cardioversion of atrial fibrillation. (3/343)

Restoration of sinus rhythm is not always followed by immediate return of effective atrial contraction. Left atrial mechanical function can be assessed by Doppler echocardiography; in the present study we measured the atrial ejection force, which is a noninvasive Doppler-derived parameter that measures the strength of atrial contraction. The aim of the present study was to evaluate the influence of clinical and echocardiographic parameters: duration and cause of atrial fibrillation, different modality of cardioversion, and left atrial size with respect to the delay in the return of effective atrial contraction after cardioversion. Seventy patients were randomly chosen to undergo cardioversion by either direct current shock or intravenously administered procainamide hydrochloride. The 52 patients who had sinus rhythm restored underwent a complete Doppler echocardiographic examination 1 h after the restoration of sinus rhythm and after 1 day, 7 days, and 1 month. The relation between clinical variables and atrial ejection force was tested. Atrial ejection force was greater immediately and 24 h after cardioversion in patients who underwent pharmacologic therapy compared to patients treated with direct current shock (11.3+/-3 versus 5+/-2.9 dynes; P<0.001). In both groups atrial ejection force increased over time. The mode of cardioversion was significantly associated with recovery of left atrial mechanical function by day 1 in univariate and multivariate analysis (odds ratio, 0.14; 95% confidence interval, 0.02-1.2). The other variable associated with the delay in the recovery of atrial function was a dilated left atrium (odds ratio, 0.16; 95% confidence interval, 0.12-1.6). Atrial ejection force is a noninvasive parameter that can be easily measured after cardioversion and gives accurate information about the recovery of left atrial mechanical function. The recovery of left atrial function was influenced by the mode of cardioversion and left atrial size.  (+info)

Importance of left atrial appendage flow as a predictor of thromboembolic events in patients with atrial fibrillation. (4/343)

AIM: The purpose of this study was to investigate the role of transoesophageal echocardiography in predicting subsequent thromboembolic events in patients with atrial fibrillation. METHODS AND PATIENTS: Transoesophageal echocardiography was performed in 88 patients with documented paroxysmal (n=53) or chronic atrial fibrillation (n=35) to assess morphological and functional predictors of thromboembolic events. Prospective selection was from patients with non-valvular atrial fibrillation who had undergone transoesophageal echocardiography because of previous thromboembolism (n=30); prior to electrical cardioversion (n=31); or for other reasons (n=27). All patients were followed up for 1 year. RESULTS: During the period of follow-up new thromboembolic events occurred in 18 of 88 patients (20%/year); 16 of these patients had a stroke and two a peripheral embolism. Univariate analysis revealed that previous thromboembolism (P<0.005; odds ratio 5.3 [CI 1.9, 12. 1]), history of hypertension (P<0.01; odds ratio 4.0 [CI 1.4, 10.4), presence of left atrial spontaneous echo contrast (P<0.025; odds ratio 3.5 [CI 1.2, 10.0]), and presence of left atrial appendage peak velocity +info)

Short-term effect of atrial fibrillation on atrial contractile function in humans. (5/343)

BACKGROUND: Conversion of chronic atrial fibrillation (AF) is associated with atrial stunning, but the short-term effect of a brief episode of AF on left atrial appendage (LAA) emptying velocity is unknown. The purpose of this study was to determine whether a short episode of AF affects left atrial function and whether verapamil modifies this effect. METHODS AND RESULTS: The subjects of this study were 19 patients without structural heart disease undergoing an electrophysiology procedure. In 13 patients, LAA emptying velocity was measured by transesophageal echocardiography in the setting of pharmacological autonomic blockade before, during, and after a short episode of AF. During sinus rhythm, the baseline LAA emptying velocity was measured 5 times and averaged. AF was then induced by rapid right atrial pacing. After either spontaneous or electrical conversion, LAA emptying velocity was measured immediately on resumption of sinus rhythm and every minute thereafter. The mean duration of AF was 15.3+/-3.8 minutes. The mean baseline emptying velocity was 70+/-20 cm/s. The first post-AF emptying velocity was 63+/-20 cm/s (P=0.02 versus baseline emptying velocity). The post-AF emptying velocity returned to the baseline emptying velocity value after 3.0 minutes. The mean percent reduction in post-AF emptying velocity was 9.7+/-21% (range, 15% increase to 56% decrease). A second group of 6 patients were pretreated with verapamil (0.1-mg/kg IV bolus followed by an infusion of 0.005 mg. kg-1. min-1). In these patients, the first post-AF emptying velocity, 58+/-14 cm/s, was not significantly different from the pre-AF emptying velocity, 60+/-13 cm/s (P=0.08). CONCLUSIONS: In humans, several minutes of AF may be sufficient to induce atrial contractile dysfunction after cardioversion. When atrial contractile dysfunction occurs, there is recovery of AF within several minutes. AF-induced contractile dysfunction is attenuated by verapamil and may be at least partially mediated by cellular calcium overload.  (+info)

Left atrial relaxation and left ventricular systolic function determine left atrial reservoir function. (6/343)

BACKGROUND: Determinants of left atrial (LA) reservoir function and its influence on left ventricular (LV) function have not been quantified. METHODS AND RESULTS: In an open-pericardium, paced (70 and 90 bpm) pig model of LV regional ischemia (left anterior descending coronary constriction), with high-fidelity LV, LA, and RV pressure recordings, we obtained the LA area with 2D automated border detection echocardiography, LA pressure-area loops, and Doppler transmitral flow. We calculated LV tau, LA relaxation (a-x pressure difference divided by time, normalized by a pressure), and stiffness (slope between x and v pressure points of v loop). Determinants of total LA reservoir (maximum-minimum area, cm(2)) were identified by multiple regression analysis. Different mean rates of LA area increase identified 2 consecutive (early rapid and late slow) reservoir phases. During ischemia, LV long-axis shortening (LAS, LV base systolic descent) and LA reservoir area change decreased (7.3+/-0.3 [SEM] versus 5.6+/-0.3 cm(2), P<0.001) and LA stiffness increased (1.6+/-0.3 versus 3.1+/-0.3 mm Hg/cm(2), P=0.009). Early reservoir area change depended on LA mean ejection rate (LA area at ECG P wave minus minimum area divided by time; multiple regression coefficient=0.9; P<0.001) and relaxation (coefficient=4.9 cm(2)xms/s; P<0.001). Late reservoir area change depended on LAS (coefficient=8 cm/s; P<0.001). Total reservoir filling depended on LA stiffness (coefficient=-0.31 cm(4)/mm Hg; P=0. 001) and cardiac output (coefficient=0.001 cm(2)xmin/L; P=0.002). The strongest predictor of cardiac output was LA reservoir filling (coefficient=301 L/minxcm(2); P<0.001). The v loop area was determined by cardiac output, LV ejection time, tau, and early transmitral flow. CONCLUSIONS: Two (early and late) reservoir phases are determined by LA contraction and relaxation and LV base descent. Acute LV regional ischemia increases LA stiffness and impairs LA reservoir function by reducing LV base descent.  (+info)

Noninvasive assessment of left atrial maximum dP/dt by a combination of transmitral and pulmonary venous flow. (7/343)

OBJECTIVES: The study assessed whether hemodynamic parameters of left atrial (LA) systolic function could be estimated noninvasively using Doppler echocardiography. BACKGROUND: Left atrial systolic function is an important aspect of cardiac function. Doppler echocardiography can measure changes in LA volume, but has not been shown to relate to hemodynamic parameters such as the maximal value of the first derivative of the pressure (LA dP/dt(max)). METHODS: Eighteen patients in sinus rhythm were studied immediately before and after open heart surgery using simultaneous LA pressure measurements and intraoperative transesophageal echocardiography. Left atrial pressure was measured with a micromanometer catheter, and LA dP/dt(max) during atrial contraction was obtained. Transmitral and pulmonary venous flow were recorded by pulsed Doppler echocardiography. Peak velocity, and mean acceleration and deceleration, and the time-velocity integral of each flow during atrial contraction was measured. The initial eight patients served as the study group to derive a multilinear regression equation to estimate LA dP/dt(max) from Doppler parameters, and the latter 10 patients served as the test group to validate the equation. A previously validated numeric model was used to confirm these results. RESULTS: In the study group, LA dP/dt(max) showed a linear relation with LA pressure before atrial contraction (r = 0.80, p < 0.005), confirming the presence of the Frank-Starling mechanism in the LA. Among transmitral flow parameters, mean acceleration showed the strongest correlation with LA dP/dt(max) (r = 0.78, p < 0.001). Among pulmonary venous flow parameters, no single parameter was sufficient to estimate LA dP/dt(max) with an r2 > 0.30. By stepwise and multiple linear regression analysis, LA dP/dt(max) was best described as follows: LA dP/dt(max) = 0.1 M-AC +/- 1.8 P-V - 4.1; r = 0.88, p < 0.0001, where M-AC is the mean acceleration of transmitral flow and P-V is the peak velocity of pulmonary venous flow during atrial contraction. This equation was tested in the latter 10 patients of the test group. Predicted and measured LA dP/dt(max) correlated well (r = 0.90, p < 0.0001). Numerical simulation verified that this relationship held across a wide range of atrial elastance, ventricular relaxation and systolic function, with LA dP/dt(max) predicted by the above equation with r = 0.94. CONCLUSIONS: A combination of transmitral and pulmonary venous flow parameters can provide a hemodynamic assessment of LA systolic function.  (+info)

The pulmonary venous systolic flow pulse--its origin and relationship to left atrial pressure. (8/343)

OBJECTIVES: The purpose of this study was to determine the origin of the pulmonary venous systolic flow pulse using wave-intensity analysis to separate forward- and backward-going waves. BACKGROUND: The mechanism of the pulmonary venous systolic flow pulse is unclear and could be a "suction effect" due to a fall in atrial pressure (backward-going wave) or a "pushing effect" due to forward-propagation of right ventricular (RV) pressure (forward-going wave). METHODS: In eight patients during coronary surgery, pulmonary venous flow (flow probe), velocity (microsensor) and pressure (micromanometer) were recorded. We calculated wave intensity (dP x dU) as change in pulmonary venous pressure (dP) times change in velocity (dU) at 5 ms intervals. When dP x dU > 0 there is a net forward-going wave and when dP x dU < 0 there is a net backward-going wave. RESULTS: Systolic pulmonary venous flow was biphasic. When flow accelerated in early systole (S1), pulmonary venous pressure was falling, and, therefore, dP x dU was negative, -0.6 +/- 0.2 (x +/- SE) W/m2, indicating a net backward-going wave. When flow accelerated in late systole (S2), pressure was rising, and, therefore, dP x dU was positive, 0.3 +/- 0.1 W/m2, indicating a net forward-going wave. CONCLUSIONS: Pulmonary venous flow acceleration in S1 was attributed to a net backward-going wave secondary to a fall in atrial pressure. However, flow acceleration in S2 was attributed to a net forward-going wave, consistent with propagation of the RV systolic pressure pulse across the lungs. Pulmonary vein systolic flow pattern, therefore, appears to be determined by right- as well as left-sided cardiac events.  (+info)

TY - JOUR. T1 - Associations of electrocardiographic P-wave characteristics with left atrial function, and diffuse left ventricular fibrosis defined by cardiac magnetic resonance. T2 - The PRIMERI study. AU - Win, Theingi Tiffany. AU - Venkatesh, Bharath Ambale. AU - Volpe, Gustavo J.. AU - Mewton, Nathan. AU - Rizzi, Patricia. AU - Sharma, Ravi K.. AU - Strauss, David G.. AU - Lima, Joao A.. AU - Tereshchenko, Larisa G.. PY - 2015/1/1. Y1 - 2015/1/1. N2 - BACKGROUND: Abnormal P-terminal force in lead V1 (PTFV1) is associated with an increased risk of heart failure, stroke, atrial fibrillation, and death. OBJECTIVE: Our goal was to explore associations of left ventricular (LV) diffuse fibrosis with left atrial (LA) function and electrocardiographic (ECG) measures of LA electrical activity. METHODS: Patients without atrial fibrillation (n = 91; mean age 59.5 years; 61.5% men; 65.9% white) with structural heart disease (spatial QRS-T angle ≥105° and/or Selvester QRS score ≥5 on ECG) but LV ...
To obtain normal values for left atrial function noninvasively, volumes of the left atrium and ventricle were calculated in 52 volunteers by 2-dimensional echocardiography. A light pen digitizing and computation system, controlled by a microprocessor
Background: Left atrial (LA) function by volume and strain analysis in children has been little studied. LA dysfunction related to aortic stenosis has been reported in adults.. Hypotheses: 1. LA volume and strain analysis is feasible and reproducible in normal children.. 2. Children with isolated congenital aortic stenosis (AS) as compared to matched controls have higher maximal LA volume (LAV) and lower total longitudinal LA strain.. Methods: Retrospective chart review and offline analysis of 2D echocardiogram images for phasic LAVs, volume indices, and longitudinal LA strain (Fig 1) by speckle tracking (TomTec software) in: 1. Healthy children with a normal echocardiogram; and, 2. Children ≥1 years of age with significant (≥ moderate) isolated AS. AS cases were compared with age, gender and BSA-matched normal controls.. Results: There were 67 normal subjects [age: 10.5 (1.3-22.1) yrs; 50 males, 17 females; BSA 1.22 (0.44-2.39) m2] studied. No significant inter-observer and intra-observer ...
We read with great interest the paper by Carluccio et al. (1) regarding the impact of left ventricular (LV) remodeling on the response to cardiac resynchronization therapy (CRT). In this elegant study, the authors performed a comprehensive assessment of LV function, showing that extensive LV remodeling at baseline is associated with poor improvement after CRT.. We wish to raise an essential issue, which may be of keen interest to the readers.. In recent years, there has been growing interest in the potential impact of CRT on atrial function, but the state of knowledge in this field is still controversial and unsettled (2-4). In the paper by Carluccio et al. (1) several baseline data concerning atrial function are presented (left atrial volume index and mitral regurgitation severity), but unfortunately there is no information related to CRT response. We believe that their excellent echocardiographic data could also be useful to better understand another debated issue (i.e., the effect of CRT on ...
Appleton C, Galloway J, Gonzalez M et al. Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult patients with cardiac disease: additional value of analyzing left atrial ejection fraction and the difference in duration of pulmonary venous and mitral flow velocity at atrial contraction. J Am Coll Cardiol. 1993; 22 (7):1972-1982 ...
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Hall, Cynthia Ann, "The role of left atrial chamber size as assessed by echocardiography in determining thromboembolic complications of atrial fibrillation" (1986). Yale Medicine Thesis Digital Library. 2684 ...
We sought to evaluate the relationship between plasma cytokine levels (sCD14, tumor necrosis factor [TNF]-alpha, and interleukin [IL]-6) and tissue Doppler derived indices of left ventricular systolic and diastolic function in patients with newly diagnosed heart failure. We enrolled 101 consecutive patients (mean age 65+/-13 years) with newly diagnosed heart failure who were hospitalized in our institute. Echocardiographic assessment was performed in all patients during the third day of their initial hospitalization. The pulsed tissue Doppler imaging (TDI) of the systolic and diastolic function of mitral annulus was characterized by the systolic wave Smv, and the diastolic waves: Emv and Amv. Left atrial kinetic energy (LAKE), an index of left atrial function, was calculated using the equation 1/2 x LASV x 1.06 x Amv(2); where LASV is left atrial systolic volume. Furthermore the ratio E/Emv and the flow propagation velocity were also calculated; where E is the rapid mitral filling wave, detected ...
In patients with MS, several studies have demonstrated that LA enlargement is a marker of increased thromboembolic risk (4,6,7,9,11,25,26). However, the great majority of studies considered LA size or volume as an indicator of risk. This study aimed to look specifically at LA shape and not just LAVs and LA function in predicting stroke. As LA dilation may not occur in a uniform fashion, LA shape might be a better measure of the pattern of LA remodeling and a better predictor of embolic risk than absolute LAV.. The results of this study show that the atrial shape adds incremental value in predicting embolic events. Additionally, in agreement with a recently published study (27), we found that LA reservoir function was also associated with an increased risk for ECE. Although the LA has 3 major roles that affect LV filling, its reservoir function represents the most important component of the LA function in MS. LA contractile force cannot overcome the mechanical obstruction across the valve and ...
Le spillover de noradrénaline dans les régions vasculaires des muscles squelettiques augmente à lexercice. Les mécanismes causant cette augmentation ne sont pas bien connus. La contraction musculaire provoque plusieurs modifications qui pourraient influencer ce spillover. Par exemple, la bradykinine est formée lors de la contraction musculaire. Comme les récepteurs B2 à la bradykinine facilitent le spillover de noradrénaline, celle-ci pourrait être impliquée dans laugmentation observée à lexercice. Nous avons étudié leffet de la bradykinine sur le spillover de noradrénaline lors de la contraction musculaire en utilisant un antagoniste spécifique des récepteurs B2, le HOE 140 (HOE), dans le muscle gracilis in situ chez le Chien. Le HOE na eu aucun effet sur le spillover de noradrénaline au repos mais a causé une baisse significative lors de la contraction, de 558 à 181 pg·min-1. Une baisse du pourcentage dextraction de la noradrénaline a été observée lors de la ...
Background Atrial stretch is considered to are likely involved in the introduction of atrial fibrillation (AF). on the LA appendage area in 24 from the 40 sufferers (60%) with Rabbit polyclonal to ABCG5. persistent AF (p=0.0006). In multivariate evaluation LA pressure was the just unbiased predictor of DFmax in the LA appendage (p=0.04 OR 1.41 95 CI 1.02 to at least one 1.94). Conclusions Higher LA pressure in sufferers with consistent AF means that these sufferers are more susceptible to stretch-related remodeling than patients with paroxysmal AF. The DF of IKK-2 inhibitor VIII AF was directly related to LA pressure in patients with persistent AF. This suggests that atrial stretch may contribute to the maintenance of AF in humans by stabilizing high frequency sources. AF was defined as the time IKK-2 inhibitor VIII period extending from the date of recurrence to the date of the ablation procedure. Patients with paroxysmal AF4 who presented to the laboratory in AF served as a comparison group ...
Mesure de la tension musculaire cardiaque : La contraction du pilier du cœur et des muscles ventriculaires découle dune dépolarisation transitoire des myocytes dans le cœur (potentiel daction). Non seulement la modification du potentiel daction du cœur a-t-elle une incidence sur lélectrophysiologie de lorgane, mais aussi sur ses propriétés mécaniques. Grâce aux paramètres de la contraction et de la relaxation comme un phénomène intégré, il est possible de mesurer la durée du cycle de contraction-repolarisation dans les tissus cardiaques pour connaître les effets du produit à létude sur le transport électrogénique (courants ioniques) et la structure protéique de la contraction.. Mesure de la tension vasculaire : Les changements dans la tension artérielle découlent des variations de lélasticité et de la tension dans larbre artériel. Ces changements sont assujettis à des facteurs exogènes et endogènes qui affinent la contractilité des tissus. Grâce aux ...
Abnormal left atrial (LA) function is a marker of cardiac dysfunction and adverse cardiovascular outcome, but is difficult to assess, and hence not, routinely quantified. We aimed to determine the feasibility and effectiveness of a fast method to measure long-axis LA strain and strain rate (SR) with standard cardiovascular magnetic resonance (CMR) compared to conventional feature tracking (FT) derived longitudinal strain. We studied 50 normal controls, 30 patients with hypertrophic cardiomyopathy, and 100 heart failure (HF) patients, including 40 with reduced ejection fraction (HFrEF), 30 mid-range ejection fraction (HFmrEF) and 30 preserved ejection fraction (HFpEF). LA longitudinal strain and SR parameters were derived by tracking the distance between the left atrioventricular junction and a user-defined point at the mid posterior LA wall on standard cine CMR two- and four-chamber views. LA performance was analyzed at three distinct cardiac phases: reservoir function (reservoir strain εs and strain
A short A2-OS interval and long mitral diastolic murmur indicate severe MS. A good chest x-ray provides information about elevated LA pressures; pulmonary congestion occurs with an LA pressure ≥18 mm Hg, interstitial edema with an LA pressure ≥25 mm Hg, and alveolar edema with LA pressure ≥35 mm Hg. Signs of PA hypertension (loud P2, right ventricular hypertrophy) in absence of another cause indicate severe MS.. A comprehensive echocardiographic Doppler study is important. MVA by Doppler half-time, when MR/aortic regurgitation (AR) are absent or trivial, is reasonably reproducible. It is essential that mitral valve morphology using a scoring system [Massachusetts General Hospital [MGH] 1 to 16; USC 0 to 4],3 or the French,4 presence of LA thrombus, and assessment of MR and its severity are carefully evaluated. Transesophageal echocardiography is important if the patient is a candidate for CBC or surgical valve repair.. Cardiac catheterization and angiography are essential in many patients. ...
Introduction: The pathophysiology of ischemia involves the cellular effect of myocardial ischemia, reactive oxygen species, and reactive inflammatory enzymes. Left atrial (LA) ischemia has been shown to have several mechanisms through which it can lead to abnormalities in left ventricular filling in early diastole and thus reduces LA passive functional reserve. In this review, we evaluated the physiological mechanisms of LA during myocardial ischemia, as previously demonstrated in experimental and clinical studies.Methods: Several databases were searched in order to find related articles. The outcome of interest included LA function measurements (measurement of LA volume) during ischemia. By applying a standardized protocol, reviewers independently extracted and assessed the studies.Results: The literature review indicated 50 publications, among which 15 studies were eligible for analysis. Assessment of LA dimension and function is essential for clinical evaluation and prognostic purposes. ...
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Objective To evaluate the predictive value of left atrial appendage (LAA) function in success of electrial cardioversion (ECV) in patients with nonvalvular atrial fibrillation (NVAF), and observe the course of the recovery of LAA systaltic function Methods To test blood flow wave patterns, peak emptying velocity (PEV) of LAA and left atrial spontaneous echo contrast (SEC) of left atrial appendage before ECV and after ECV 24 hours, 3 days and 1 week in 60 patients with NVAF by using transesophageal echocardiography (TEE) Results (1) Patients with LAAPEV20 cm/s had a ECV success rate of 75%, in contrast, LAAPEV20 cm/s had that of 30% (2) LAA blood flow wave patterns converted to a organized contraction patterns LAAPEV (2310 cm/s) was lower than that (3010 cm/s) before ECV (P0001); SEC could be generated in 8 patients, intensified in 11 patients Conclusion LAA mechanical activity prior to ECV is highly
Objective: To compare the value of current harmonic transthoracic and transesophageal echocardiography for assessing echocardiographic markers of thromboembolic risk and identify left atrial thrombi in patients with atrial fibrillation and atrial flutter prior to cardioversion and/or overdrive stimulation. Transesophageal echocardiography has been suggested for guiding cardioversion in patients with atrial fibrillation and atrial flutter, because of its high accuracy for identifying left atrial thrombi. More recent studies have demonstrated that harmonic echocardiography may allow transthoracic detection of left atrial thrombi and assessment of left atrial appendage function. Setting: Tertiary cardiac referral centre. 172 Patients with atrial fibrillation and/or atrial flutter who were scheduled for cardioversion and/or overdrive stimulation were examined both by harmonic transthoracic and multiplane transesophageal echocardiography by independent observers to assess left atrial chamber and ...
We analyzed the reports of 1,288 consecutive transesophageal echocardiograms (TEE) performed between the years 1993 through 1997. All TEE were performed using Omniplane 5 MHz probes on Hewlett Packard Sonos 1000 echocardiographs, according to recognized guidelines (16). Echocardiograms with SEC were selected and reviewed. Patients with swirling SEC in the LA who were in NSR during TEE were chosen for analysis. Patients in AF or flutter at the time of TEE were excluded from this study. Left atrial SEC was diagnosed by the presence of swirling dynamic smoke-like echoes within the atrial cavity that was distinct from white noise artifact. The presence and severity of SEC were determined independently by two different echocardiographers, and any discrepancy was resolved by consensus. Spontaneous echo contrast was graded as 0 = no smoke, 1+ = mild smoke visible in some portion of the LA, 2+ = dense smoke that appeared throughout the LA. The presence of LA thrombus, diagnosed as a clearly defined ...
Objectives. This study was conducted to determine the implications of negative findings on a transesophageal echocardiographic study in which neither a vegetation nor an abscess is identified in patients with clinically suspected infective endocarditis.. Background. Echocardiography is the procedure of choice for evaluating suspected infective endocarditis in patients. Transesophageal echocardiography has been shown to be superior to transthoracic imaging. Although the importance of positive results or a diagnostic study is known, the significance of negative findings on a transesophageal study is not clear.. Methods. All transesophageal echocardlographic studies performed over a 2-year period for suspected infective endocarditis were reviewed and the clinical course of patients with an initially negative study result was assessed to determine their final diagnosis. Results. Of the 105 patients identified. 65 bad a negative transesophageal study result. In the majority of this group (56 of 65), ...
Dalwallinu workers will begin work this month to update the towns water infrastructure by building a new, larger water tank to improve the towns water supply.. Around 24 Western Australian workers will be involved in the $8.8 million project, including 11 local sub-contractors. The project will increase Water Corporations capacity to store water and provide a more consistent water pressure to around 350 properties in the town. Works will include the construction of a new concrete water storage tank, two new booster pump stations and 2.2 kilometres of underground pipework connecting the new tank to the scheme.. The new tank and a booster pump will be constructed on Water Corporation land in Dalwallinu, opposite Strickland Drive, near Mclevie Way. The new underground pipeline will be laid along Leahy Street, Strickland Drive, Great Northern Highway and Watheroo Road.. The second booster pump station will be constructed at the Water Corporations existing Pithara site, approximately 20 km from ...
Dear NSF forum members: I have just been diagnosed with flat back syndrome after a lumbar spinal fusion that was done 2 years ago because of scoliosis and degenerative disc disease. Ive had a consultation with Dr. Pashman at Cedars Sinai Spine Center and he is advising revision surgery from T10 to the pelvis. I have been trying to find another surgeon in the LA area for a second opinion but have yet to find one who specifically mentions revision surgery or flat back syndrome on their
TY - JOUR. T1 - Best method in clinical practice and in research studies to determine left atrial size. AU - Lester, Steven Jay. AU - Ryan, Elizabeth W.. AU - Schiller, Nelson B.. AU - Foster, Elyse. PY - 1999/10/1. Y1 - 1999/10/1. N2 - Although the anteroposterior dimension of the left atrium is universally used in clinical practice and research, we hypothesized that it may be an inaccurate surrogate for volume because its use is based on the unlikely assumption that there is a constant relation among atrial dimensions. The following measurements of the left atrium were made at end ventricular systole: (1) M-mode-derived anteroposterior linear dimension from the parasternal long-axis view; (2) digitized planimetry of the left atrial (LA) cavity from the apical 4-chamber view; and (3) digitized planimetry of the LA cavity from the apical 2-chamber view. The following volume calculations were obtained from these digital measurements: (1) volume derived from the M-mode dimension assuming a ...
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Milani, R. V., Davis, C. T., Lavie, C. J. and Mehra, M. R. (2005). Importance of left atrial volume in predicting reduced peak aerobic capacity in advanced systolic dysfunction. In: Journal of Heart and Lung Transplantation. , , (S129-S130). . doi:10.1016/j.healun.2004.11.292 ...
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Sugimoto T, Robinet S, Dulgheru R, Bernard A, Ilardi F, Contu L, Addetia K, Caballero L, Kacharava G, Athanassopoulos GD, Barone D, Baroni M, Cardim N, Hagendorff A, Hristova K, Lopez T, de la Morena G, Popescu BA, Penicka M, Ozyigit T, Rodrigo Carbonero JD, van de Veire N, Von Bardeleben RS, Vinereanu D, Zamorano JL, Go YY, Marchetta S, Nchimi A, Rosca M, Calin A, Moonen M, Cimino S, Magne J, Cosyns B, Galli E, Donal E, Habib G, Esposito R, Galderisi M, Badano LP, Lang RM, Lancellotti P. Echocardiographic reference ranges for normal left atrial function parameters: results from the EACVI NORRE study. Eur Heart J Cardiovasc Imaging. 2018 06 01; 19(6):630-638 ...
Results TTE at 1 month showed persistent iASD in 57% (1M-iASD). Mean LA pressure after clip was significantly higher in patients with 1M-iASD than patients without 1M-iASD (17±6 mm Hg vs 15±5 mm Hg, p=0.01). Among patients with 1M-iASD, 24 patients (35%) had persistent iASD at 12 months (12M-iASD). Mean LA pressure after clip was significantly higher in patients with 12M-iASD than patients without 12M-iASD (19±6 mm Hg vs 16±6 mm Hg, p=0.04). Patients with 12M-iASD did not significantly differ from patients without 12M-iASD in terms of right heart enlargement, estimated systolic pulmonary artery pressure, New York Heart Association functional class and brain natriuretic peptide at 12 months. Logistic regression analysis, however, showed that mean LA pressure after clip was significantly associated with persistent iASD at 12 months in patients with 1M-iASD even after adjustment for cardiac index after clip and the prevalence of mitral regurgitation ≥3+ at 12 months (OR 1.10 per 1 mm Hg, 95% ...
The receiver-operating characteristic (ROC) curve analysis for red blood cell distribution width in predicting left atrial spontaneous echo contrast. RDW |13
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CHINA is #1! in EXPLOSIONS, air pollution, execution of political dissenters, organ harvesting of political dissenters, skinning animals alive! https://www.facebook.com/ebaumsworld/videos/10153155166912424 WARNING: DO NOT MICROWAVE YOUR ARMPITS. sweat release toxins (beam me up Scotty, there is no intelligent life down here) Cancer rates will go through the roof. The body wont be able to process the toxins! Lymphatic system will be blocked. Costly health syndromes and financial costs will ensue. Buyer beware...UNTIL the rest of us are stuck paying their medical costs. these people should have the optional surgery to seal their lips and nostrils before they breed NEWSFLASH! COTTERIZING your LIPS and NOSTRILS prevents unwanted SNOT! LA reservoir plastic balls Nathan Krekula, biologist and operations manager at Wisconsin Diagnostic Laboratory warned, I don t believe that in the long run this provides a good strategy in protecting the water. I believe that this will increase evaporation due to a ...
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CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): In recent NIST evaluations on sentence boundary detection, a single error metric was used to describe performance. Additional metrics, however, are available for such tasks, in which a word stream is partitioned into subunits. This paper compares alternative evaluation metrics-including the NIST error rate, classification error rate per word boundary, precision and recall, ROC curves, DET curves, precision-recall curves, and area under the curves-and discusses advantages and disadvantages of each. Unlike many studies in machine learning, we use real data for a real task. We find benefit from using curves in addition to a single metric. Furthermore, we find that data skew has an impact on metrics, and that differences among different system outputs are more visible in precision-recall curves. Results are expected to help us better understand evaluation metrics that should be generalizable to similar language processing tasks.
According to the FDA, use of Lariat Suture Delivery Device linked to patient deaths & other complications when used to close the left atrial appendage.
We know the atrial pressure wave forms vary between right and left atrium .In the right atrium a waves are prominent and taller than v waves, while the reverse is true in left atrium . The reasons for tall left atrial v waves are V waves are passive atrial filling waves and are timed during ventricular…
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Wow, umm... generally I dont even respond unless it seems like something REALLY needs responding to. Im afraid this particular post is in dire NEED of responding to... on 2 fronts. 1.) Shelby, whoa man, lets back it up here. Ill start by saying I read this e-mail in its entirety. I even looked up the words I had never seen used in this context (mainly orthogonality). And having been a big proponent of what I think youre talking about Ill say this, I think youre correct, but well get back to that. Daniel Glazman seems to have hit the nail on the head here. I wasnt around 3 years ago so I cant even begin to guess what when down, or why you seem so bitter. Im also not going to read through a battery of 3 year old material to find out why youre so bitter, suffice it to say, coming here and insulting people because you were right and they were wrong is... well the height of arrogance. They may have totally seen what youve been saying and completely agree with you from a technical point ...
Cardiovascular Journal of Africa Vol 26, No 4: RV function and hepatosteatosis in non-alcoholic fatty liver disease, Left atrial function and conduction in Maras powder users and smokers, Postoperative atrial fibrillation with left atrial myxoma, Sickle cell trait and chronic kidney disease in Congolese patients, Clinical outcomes of IABP during coronary artery bypass surgery, Anaemia among heart failure patients at Brazzaville Hospital, Antibiotic recipe for arrhythmic disaster, Unusual cause of large fibrinous pericardial effusion, Heparin-induced thrombocytopenia with thrombosis
Cardiovascular Journal of Africa Vol 26, No 4: RV function and hepatosteatosis in non-alcoholic fatty liver disease, Left atrial function and conduction in Maras powder users and smokers, Postoperative atrial fibrillation with left atrial myxoma, Sickle cell trait and chronic kidney disease in Congolese patients, Clinical outcomes of IABP during coronary artery bypass surgery, Anaemia among heart failure patients at Brazzaville Hospital, Antibiotic recipe for arrhythmic disaster, Unusual cause of large fibrinous pericardial effusion, Heparin-induced thrombocytopenia with thrombosis
Methods and apparatus for closing a left atrial appendage are described. The methods rely on introducing a closure tool from a location beneath the rib cage, over an epicardial surface, and to the exterior of the left atrial appendage. The closure device may then be used to close the left atrial appendage, preferably at its base, by any one of a variety of techniques. A specific technique using graspers and a closing loop is illustrated.
TY - JOUR. T1 - The effect of nitroglycerin upon pulmonary and left atrial pressures in patients with mitral stenosis. AU - Rothbaum, Donald A.. AU - Dillon, James C.. AU - Feigenbaum, Harvey. PY - 1976/2. Y1 - 1976/2. N2 - In all nine patients studied with mitral stenosis and no evidence of left ventricular failure, nitroglycerin caused a decrease in pulmonary arterial, left atrial, and left ventricular pressures and pulmonary vascular resistance. The decrease in left atrial pressure was attributable to the combination of a reduction in left ventricular filling pressure and a reduction in mitral valve gradient. While there was no significant mean change in heart rate, cardiac index, or mitral valve flow, there was a significant correlation between a decrease in each of these determinants of mitral valve gradient and the observed decline in left atrial pressure in individual patients. However, even those patients who had an increase in heart rate or cardiac output, either of which normally ...
Heart function improved by up to 25 percent in a trial using gene therapy to reverse cardiac damage from congestive heart failure in a large animal model, Mount Sinai researchers report. This is the first study using a novel vector for gene therapy to improve heart function in non-ischemic heart failure.. The results of the study will be published online in the Journal of the American College of Cardiology on Monday, September 25, at 2 pm.. In heart failure, a weakened or damaged heart no longer pumps blood effectively. This potentially fatal disease affects almost 6 million Americans, according to the American Heart Association, and is a major cause of morbidity and mortality, especially in elderly patients. Despite this toll, there has been little progress toward any kind of cure. Novel therapeutic approaches, such as gene therapy and cell therapy, hold the promise of complementing or replacing existing therapies for congestive heart failure.. "Mount Sinai has performed pioneering work on gene ...
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Looking for online definition of atrial systole in the Medical Dictionary? atrial systole explanation free. What is atrial systole? Meaning of atrial systole medical term. What does atrial systole mean?
LEFT ATRIAL APPENDAGE ANATOMY. The publication chosen for the description of the LAA anatomy was signed by DeSimone et al.[3] from Mayo Clinic, Rochester, MN, USA. The three-dimensional LAA morphology is, by itself, the substrate for thrombus generation, and should be the subtract for embolism due to its direct connection to the left-sided circulation. The LAA mesodermal justify its exclusion from the atrial circulation and thereby can lead to a significant reduction in stroke risk. This process also provides insight into the LAA as an endocrine organ, its fluid homeostasis involvement, and its autonomic nervous system connection. The surrounding LAA structural knowledge arrangement is critical to identify the endocardial and epicardial landmarks perspective to improve devices placement. Furthermore, correlation of the LAA body, neck, and ostium to the surrounding anatomy can also improve both procedural safety and efficacy. Also, a working knowledge of the regional anatomy adds a prudent degree ...
Left atrial appendage (LAA) exclusion therapy is becoming an important management tool for minimizing stroke potential. More than 30 percent of strokes in individuals over the age of 75 years are due to atrial fibrillation.
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Mitral regurgitation is expected to occur only in systole during left ventricular contraction. In rare pathological states , if LV pressure exceeds the mean LA pressure at any point in diastole , small puffs of regurgitation into LA can occur.The genesis of this MR and its hemodynamic significance has generated much interest . Causes…
Not all echo laboratories have the capability of measuring direct online 3D images, but do have the capability of turning 3D images into 2D ones
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Le certificat de la fondation Health on the Net (HON) garantit que ce site Web est conforme aux 8 principes du Code de Conduite HONcode tablis par la fondation HON, la date de certification indiqu e ci-dessus. Le responsable du site sest engag ce que son site respecte les huit principes thiques durant la validit du certificat.. Cependant, malgr le syst me de plaintes mis en place, la revue p riodique et les syst mes de surveillance automatiques des sites certifi s pour garantir au maximum la conformit dun site Web certifi avec les principes thiques HONcode, il est impossible d carter tous les risques dincoh rence qui peuvent appara tre.. La fondation HON et/ou ses partenaire(s) ne sera/seront en aucun cas responsable des dommages r sultant de lutilisation ou de limpossibilit dutiliser les sites Web certifi s. De m me, la fondation et/ou ses partenaire(s) ne peut/peuvent tre tenue(s) responsable du contenu de ces sites Web certifi s. Que ce soit linformation qui y est dispens e, ou de ...
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A membrane applied to the ostium of an atrial appendage for blocking blood from entering the atrial appendage which can form blood clots therein is disclosed. The membrane also prevents blood clots in the atrial appendage from escaping therefrom and entering the blood stream which can result in a blocked blood vessel, leading to strokes and heart attacks. The membranes are percutaneously installed in patients experiencing atrial fibrillations and other heart conditions where thrombosis may form in the atrial appendages. A variety of means for securing the membranes in place are disclosed. The membranes may be held in place over the ostium of the atrial appendage or fill the inside of the atrial appendage. The means for holding the membranes in place over the ostium of the atrial appendages include prongs, stents, anchors with tethers or springs, disks with tethers or springs, umbrellas, spiral springs filling the atrial appendages, and adhesives. After the membrane is in place a filler substance may be
53. 54. 55. 56. 57. 58. 59. 60. involvement in intracardiac thrombogenesis. Thromb Res 2003;111(3):137-42. Yamashita T, Sekiguchi A, Iwasaki YK, et al. Thrombomodulin and tissue factor pathway inhibitor in endocardium of rapidly paced rat atria. Circulation 2003;108(20):2450-2. Fukuchi M, Watanabe J, Kumagai K, et al. Increased von Willebrand factor in the endocardium as a local predisposing factor for thrombogenesis in overloaded human atrial appendage. J Am Coll Cardiol 2001;37(5):1436-42. Kumagai K, Fukuchi M, Ohta J, et al. Motion of left atrial appendage as a determinant of thrombus formation in patients with a low CHADS2 score receiving warfarin for persistent nonvalvular atrial fibrillation. ) was seen in patients with LV dysfunction even in the absence of AF,41,42 which suggests that intact LV function may help decrease the risk of thromboembolism. 44 It is therefore possible that decreased nitric oxide in addition to increased free radicals may increase thrombotic milieu. 48 Altered ...
The developmental origin of the c-kit expressing progenitor cell pool in the adult heart has remained elusive. Recently, it has been discovered that the injured heart is enriched with c-kit(+) cells, which also express the hematopoietic marker CD45.In this study, we characterize the phenotype and transcriptome of the c-kit+/CD45+/CD11b+/Flk-1+/Sca-1±(B-type) cell population, originating from the left atrial appendage. These cells are defined as cardiac macrophage progenitors. We also demonstrate that the CD45+ progenitor cell population activates heart development, neural crest and pluripotency-associated pathways in vitro, in conjunction with CD45 down-regulation, and acquire a c-kit+/CD45-/CD11b-/Flk-1-/Sca-1+ (A-type) phenotype through cell fusion and asymmetric division. This putative spontaneous reprogramming evolves into a highly proliferative, partially myogenic phenotype (C-type).Our data suggests that A-type cells and cardiac macrophage precursor cells (B-type) have a common lineage ...
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We followed 2844 participants from the Tromsø Study from 1994 to 2012. Information on LA size and CHA2DS2-VASc score (age, sex, congestive heart failure, hypertension, vascular disease, stroke and diabetes) were obtained at baseline. AF status was recorded from medical records. The outcome measure was all strokes. The association between covariates and stroke was investigated by means of multivariate logistic regression analysis ...
According to Seoul cancer registry data (2000), cancer became the leading cause of death in Korea, accounting for 23.9% of all deaths and gastric cancer is the most prevalent malignant neoplasm, comprising 20.8% of all cancers. Korea and some part of Asian countries have the highest incidence of gastric cancer in the world. Therefore, gastrectomy became one of the most common cancer operation in Korea. Thanks to early detection and intervention, the mortality of early gastric cancer drops dramatically and is now believed to be one of the most curable diseases among all the cancers. However, after successful operation and the declaration of cure of the stomach cancer, the patients are left without stomach for all his remaining life. If the patients lose most of his stomach tissue, there are several problems, which include loss of reservoir function for food and indigestion. Besides, loss of appetite is of the paramount importance because the stomach is an important endocrine organ controlling the ...
Editors Comment: Acheiving high quality images in patients with arrhythmia can be challenging. A number of approaches can be used to optimise image acquisition including arrhythmia suppresion (timing to ignore "extra" beats within a set number of milliseconds from the preceeding QRS), triggered acquisition as opposed to retropective gating (with the advise to change the number of segments to increase the total number of phases to avoid abrupt ending of cine before end-diastole), and finally real time cine as a last resort. A more detailed "How I Image in Arrhythmia" will be available soon. Submit your case here ...
Concomitant conditions: Childbearing potential without proper contraceptive measures, pregnancy, or breast feeding. Hypersensitivity to investigational treatment. Calculated creatinine clearance (CrCl) , 15 mL/minute at the screening visit. Hepatic disease which is associated with coagulopathy leading to a clinically relevant bleeding risk. Any severe condition that would limit life expectancy to less than 3 months (eg, advanced malignancy, etc.). Planned invasive procedure with potential for uncontrolled bleeding or increased risk of stroke, including major surgery, cardiac catheterization, or cardioversion prior to the end-of-treatment TEE. Inability to take oral medication. Ongoing drug addiction or alcohol ...
Pressure pulses were obtained under direct vision, in the left atrium of subjects without clinical evidence of cardiac disease and in patients with mitral valvular disease, after exposure of their hearts during the course of surgical intervention. It was found that the c wave is produced by valvular closure and the subsequent fall of pressure during early ventricular systole (x wave) is related to atrial relaxation. Evidence is presented that mitral incompetence cannot be determined from direct atrial recordings, unless the Degrees of insufficiency is of great magnitude.. ...
More than half of the patients who have suffered a stroke with no well-defined aetiology have an enlarged left atrial appendage of the heart, according to a Finnish study. The results indicate that the enlargement of the left atrial appendage may be an independent risk factor of strokes with cardiac origin.
Patient had 2 CABGs done and while the heart was retracted, sutures were placed around the base of atrial appendage and tied. A heavy silk tie was use
View our Los Angeles weather radar map. The ABC7 Mega Doppler 7000 HD keeps you up-to-date with live weather conditions for the greater LA area.
Cardiovascular Disease 1 Cardiovascular Disease 1. More target specific oral anticoagulants (TSOAC) 2. Vorapaxar (Zonivity) 3. Continued noise about a polypill 4. WATCHMAN Left Atrial Appendage
La cavidad bucal representa un ambiente del husped que tiene caracteristicas que favorecen la ubicacion y el crecimiento de una gran variedad de microorganismos. Las areas con diferentes ambientes fisicoquimicos y nutricionales, como la mucosa del carrillo, la lengua, las hendiduras gingivales y la superficie de los dientes, favorecen la adherencia y el crecimiento de tipos selectos de microbios. Estos microorganismos estan regulados por una serie de factores conocidos como determinantes ecologicos internos y externos. La ecologia no solo estudia las interrelaciones entre los organismos y su ambiente vivo y no vivo, sino ademas el papel y contribuciones de estos organismos en la naturaleza y en los ciclos biolgicos y ecologicos que mantienen en equilibrio los delicados eventos que ocurren en un ambiente determinado ...
Disclosed is a closure catheter, for closing a body cavity such as a vessel, or the left atrial appendage of the heart. The closure catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may thereafter be used to draw the tissue radially inwardly, to close the body cavity. Methods are also disclosed.
Defective conduit function of the oesophagus readily induces clinical symptoms and may have serious effects on nutrition and the lungs, the latter resulting from aspiration of gastro-oeophageal contents. Oesophageal pain and dysphagia caused by benign or malignant diseases of the muscular layer or epithelium are often disabling....
Here you may find the Brain and spinal cord: Abbr. crossword clue answers and solutions. This clue was last seen on LA Times Crossword February 14 2020 Answers In case the clue doesnt fit or theres something wrong please leave a comment below. ...
The Tacta Optimal Experience - Perfectly Balanced Comfortable to hold due to the ergonomically designed handle Low pipetting and tip ejection forces that .
A 76-year-old woman with a medical history of permanent atrial fibrillation (CHA2DS2-VASc stage 4) underwent left atrium (LA) appendage closure with a LARIAT device (SentreHEART, Redwood City, California). She was then maintained on aspirin only due to major bleeding during postoperative period. Two years later, she presented with a mechanical fall. Chest computed tomography with contrast, done as work-up for trauma, showed a large unenhanced LA mass (Figure 1A). She underwent further evaluation with transesophageal echocardiogram (TEE), which showed very severe LA dilatation (LA volume = 150 ml or 79 ml/m2), LA appendage occlusion, and a new, very large, sessile mass attached to the posterior wall of the LA (Figures 1B and 1C, Online Video 1). The mass did not enhance after contrast infusion (Figure 1D, Online Video 2). This mass was new compared to her prior TEE during the procedure and the findings were consistent with thrombus. She was treated with vitamin K antagonist and had no clinical ...
Detecting left atrial enlargement is frequently suspected in line with the presentation of signs and symptoms of the underlying cardiogenic condition. Once other tests addressing other complications are carried out to assist eliminate any potentially existence-threatening disorders, additional testing searching in the structure from the heart can be achieved to find out if left atrial enlargement exists.. Probably the most generally done test to identify left atrial enlargement is applying imaging methods known as echocardiograms. To control your emotions by utilizing seem waves to consider images of the center structures. Using other imaging tests, namely CT or MRI scans, may also be used to identify left atrial enlargement.. With respect to the underlying condition, treatment will normally follow. For instance, treating high bloodstream pressure calls for the effective use of bloodstream pressure medication for example beta-blockers and diuretics. Also, maintaining a healthy diet plan, ...
Transcatheter left atrial appendage (LAA) ligation may represent an alternative to oral anticoagulation for stroke prevention in atrial fibrillation. This study sought to assess the early safety and efficacy of transcatheter ligation of the LAA
Results From the 138 consecutive ECVs, 8 were excluded due to incomplete datasets, 15 due to atrial flutter being the starting rhythm and 3 due to non-concurrent classification of the Fw by the two cardiologists.. Out of the 112 pre-ECV ECGs, 32% (36/112) had cFw in V1, lead II or both. After ECV, SR was immediately achieved in 95% (106/112) of patients. Overall, of those that were successful, 46% (49/106) were back in AF at the 4-week clinic visit. All patients with cFw had successful initial ECV. At follow-up, 75% (27/36) of patients with cFw on pre-ECV remained in SR compared with 43% (30/70) of patients with fFw who had a successful initial ECV (p = 0.001, Fishers exact test).. The cFw and fFw groups were of the similar mean age (70.5 vs. 71.2, p = 0.72). Amiodarone use was similar between groups (8% vs. 17%, p = 0.26) as was left atrial size (4.2 vs. 4.4 cm, p = 0.3); left atrial volume (59 vs. 54 mls, p = 0.5) and indexed left atrial volume (41.8 vs. 39.0 mls/m2, p = 0.34) (Table 1). ...
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An automated irrigation system allows perfect control of the amount of water being used in the garden. Each area (also called Zones or stations) can be fine-tuned to achieve maximum benefit for minimal water and combined with intelligent plant selection and grouping can save large amounts of water (and money). Automated irrigation systems also allow for quick and easy manual adjustment of the quantity of water across the seasons. This adjustment can sometimes be automated by the addition of a rain sensor to the system which recognizes the presence of rain and adjusts the system to compensate on a daily basis. Automated sprinkler systems can get complicated when tanks, booster pumps and remote access is involved, but even the most inexpensive, timed shut-off valve fitted to the sprinkler hose pipe at the tap can save you the frustration of forgetting about the sprinkler/s and turning your garden into a temporary (and very expensive wetland) for a couple of hours. There are many different types of ...
The LARIAT® Suture Delivery Device permanently closes the Left atrial appendage (LAA), which is a benefit for individuals with Atrial Fibrillation (AFib) who cannot tolerate blood thinners.. The left atrial appendage (LAA) is a small, ear-shaped sac in the muscle wall of the left atrium (top left chamber of the heart). The LAA is a structure in the heart that normally contracts, allowing blood to flow in and out of the LAA. For patients with AFib, the most common heart rhythm disorder, the LAA no longer rhythmically contracts, creating a sluggish blood flow that can cause blood to pool and clot. These blood clots can lead to stroke. About 90% of the clots in atrial fibrillation originate in the LAA. Atrial fibrillation patients are often prescribed a blood thinners, such as warfarin or Coumadin or newer blood thinners such as Xarelto, Eliquis to prevent clotting; however these drugs cannot be tolerated by all patients.. During the LARIAT procedure, a local anesthetic is used to numb the area ...
Dr. Vivek Reddy from Mount Sinai School of Medicine in New York City gave a very well referenced and persuasive presentation on the Watchman device which closes off the Left Atrial Appendage to prevent clots and strokes. The theory behind the Watchman device is that most A-Fib clots originate in the Left Atrial Appendage (LAA). The Watchman closes off the LAA where 90-95% of A-Fib strokes come from. Its a very low risk procedure that takes as little as 20 minutes to install. Afterward, you would usually not need to be on blood thinners. (For more, see my article, The Watchman Device: The Alternative to Blood Thinners).. Dr. Reddy certainly persuaded me that the FDA should approve the Watchman device. Dr. Reddy, earlier in Washington, had made the same persuasive arguments before the FDA.. Dr. Andrew Farb from the FDA took the bull by the horns and gave his perspective on the various LAA Closure (Occlusion) Devices. But as one would expect, he didnt indicate how the FDA would rule on the ...
A left atrial appendage closure device can be used for atrial fibrillation patients to help prevent strokes and as an alternative to blood thinners such as warfarin (Coumadin).. In atrial fibrillation, the hearts upper chambers, or atria, beat irregularly. Pooling of blood flow during atrial fibrillation in an area called the left atrial appendage can increase the risk of blood clot formations that could travel to the brain and cause a stroke.. To perform the procedure, a catheter is inserted over a guide wire through a small incision in the thigh. This catheter travels up a vein and into the right atrium then across the atrial septum and into the left atrium of the heart.. The closure device is deployed securely into the left atrial appendage and the catheter and guide wire are removed.. With the device in place, the left atrial appendage is closed off from blood flow, reducing the risk of blood clot formation and strokes.. ...
Welcome to the The Center for Hearing Loss Help Local Pages. Here you can find local information about Hearing & Ear Testing in Lake Charles, LA. We have compiled a list of businesses and services around around Lake Charles, including Ear, Nose and Throat Specialists, Audiologists, and Hearing Loss Specialists that should help you with your search. In order to better help you find what you are looking for, the rest of the information on this page has also been targeted to Ear Nose & Throat. We hope this page helps satisfy your local needs.
The final diagnosis was AL (primary) amyloidosis and smoldering multiple myeloma with cardiac involvement. Treatment was started with CYBord (velcade, cytoxan, dexamethasone). Enoxaparin therapy was started for the left atrial appendage thrombus. Given major cardiac involvement, and a clinically estimated 5 yr overall survival of 40%, ICD implantation for primary prevention was not recommended. Perspective: Several key findings of cardiac amyloidosis were identified in this study. Atrial fibrillation is common in this population, for which real-time cine imaging was helpful. CMR has not gained widespread use for LAA thrombus detection, despite prior reports suggesting high sensitivity and specificity. This may be attributable to the overall low incidence of thrombus in study populations comparing CMR to transesopohageal echocardiography2. With the addition of three dimensional contrast MRA, which was not performed in this study, detection may approach that of transesophageal echocardiography. ...
Objective: To determine the efficacy of using echocardiography, compared with cardiac catheterization, to diagnose elevated left ventricular filling pressure (LVFP), according to the 2016 American Society of Echocardiography and the European Association of Cardiovascular Imaging (ASE/EACVI) recommendations, among patients with at least one coronary
Normal atrial function is essential for embryogenesis, as inactivation of the MYL7 gene was embryonic lethal at ED10.5-11.5. ... Importantly, overexpression of ALC-1 was shown to attenuate heart failure in pressure-overloaded animals, by enhancing left ... Huang C, Sheikh F, Hollander M, Cai C, Becker D, Chu PH, Evans S, Chen J (December 2003). "Embryonic atrial function is ... Atrial Light Chain-1 (ALC-1), also known as Essential Light Chain, Atrial is a protein that in humans is encoded by the MYL4 ...
... is a function of atrial contraction. The ratio between e' and a' is also a measure of diastolic function, in addition to the ... is a measure of left ventricular diastolic function, and has been shown to be relatively independent of left ventricular ... Before the advent of tissue Doppler, systolic function was usually assessed with Ejection fraction (EF), and diastolic function ... this pressure difference is both a function of the pressure drop during early relaxation and the initial atrial pressure. In ...
Theodorakis GN, Panou F, Markianos M, Fragakis N, Livanis EG, Kremastinos DT (February 1997). "Left atrial function and atrial ... That's due to increase in left atrial pressure and left ventricular filling pressure, which is due to decreased cardiac output ... and decreased left atrial total emptying fraction associated with ventricular pacing. The loss of physiologic timing of atrial ... Ventricular pacing is associated with elevated right and left atrial pressures, as well as elevated pulmonary venous and ...
The AV node connects the atrial and ventricular chambers. It functions to carry the electrical impulse from the atria to the ... While the left abdominal air sac is large and lies to the left of the mesentery.[61] The connection from the main mesobronchi ... Function. The common ostrich is an endotherm and maintains a body temperature of 38.1-39.7 °C (100.6-103.5 °F) in its extreme ... Kidney function. Common ostrich kidneys are fairly large, and so are able to hold significant amounts of solutes. Hence, common ...
... atrial function MeSH G09.330.582.075.100 --- atrial function, left MeSH G09.330.582.075.200 --- atrial function, right MeSH ... ventricular function MeSH G09.330.582.962.800 --- ventricular function, left MeSH G09.330.582.962.900 --- ventricular function ...
Effects of balloon mitral valvuloplasty on left atrial function in mitral stenosis as assessed by pressure-area relation. J Am ... Assessment of left atrial pressure-area relation in humans by means of retrograde left atrial catheterization and ... He subsequently made studies on the elastic properties of aorta and the function of left atrium. A large part of his research ... Aortic function in arterial hypertension determined by pressure-diameter relation: Effects of diltiazem. Circulation. 1997 Sep ...
The AV node connects the atrial and ventricular chambers. It functions to carry the electrical impulse from the atria to the ... While the left abdominal air sac is large and lies to the left of the mesentery. The connection from the main mesobronchi to ... The ureters leave the ventral caudomedial surface and continue caudally, near the midline into the opening of the urodeum of ... For example, they use their wings to cover the naked skin of the upper legs and flanks to conserve heat, or leave these areas ...
This appears to "function as a decompression chamber during left ventricular systole and during other periods when left atrial ... Left atrial appendage occlusion is an experimental treatment to prevent stroke in atrial fibrillation. The left atrial ... The case of a disappearing left atrial appendage thrombus: direct visualization of left atrial thrombus migration, captured by ... 1999). "Left atrial appendage: structure, function, and role in thromboembolism: Review". Heart. 82 (5): 547-54. doi:10.1136/ ...
Left atrial flutter is considered atypical and is common after incomplete left atrial ablation procedures. Atypical atrial ... Prolonged atrial flutter with fast heart rates may lead to decompensation with loss of normal heart function (heart failure). ... Type I atrial flutter, also known as common atrial flutter or typical atrial flutter, has an atrial rate of 240 to 340 beats/ ... A blood clot in the left atrial appendage is particularly important as the left side of the heart supplies blood to the entire ...
RAI = right atrial area / left atrial area. These measurements are made from the apical four chamber view. Large validation ... developed several Doppler echocardiographic numeric parameters over the last two decades to assess cardiac diastolic function. ... 2011; 124: A11559 Right atrial to left atrial area ratio on early echocardiography predicts long-term survival after acute ... from the standard transthoracic Doppler echocardiogram measurements of the right atrial area divided by the left atrial area. ...
Vengen ØA, Ellingsen Ø, Lande K, Ilebekk A. Significance of right atrial function during right sided inotropic stimulation of ... Vengen ØA, Lande K, Ellingsen Ø, Ilebekk A. Cardiac adjust¬ments to left side inotropic stimulation of in situ pig hearts. Am J ... Vengen ØA, Ellingsen Ø, Ilebekk A. Forward diastolic flow in pulmonary artery induced by right atrial contraction of in situ ... Kemi OJ, Ellingsen Ø, Smith GL, Wisløff U. Exercise-induced changes in calcium handling in left ventricular cardiomyocytes. ...
Left heart. *(pulmonary veins) → left atrium (atrial appendage) → mitral valve → left ventricle → aortic valve (aortic sinus ... During diastole, a normally-functioning mitral valve opens as a result of increased pressure from the left atrium as it fills ... Diastole ends with atrial contraction, which ejects the final 30% of blood that is transferred from the left atrium to the left ... displaystyle A(x,t)=A_{0}\left(1-[1-{\Lambda }(t)]{x \over {L}}\right)^{2}}. ∫. 0. L. p. (. x. ,. t. ). ∂. A. ∂. x. d. x. =. [ ...
... early-to-atrial left ventricular filling ratio), the E (early left ventricular filling) deceleration time, and the isovolumic ... Compromise of left ventricular forward function may result in symptoms of poor systemic circulation such as dizziness, ... Backward failure can be subdivided into the failure of the left atrium, the left ventricle or both within the left circuit. The ... Left-sided failure[edit]. The left side of the heart is responsible for receiving oxygen-rich blood from the lungs and pumping ...
The atrial lead is the curved one making a U shape in the upper left part of the figure. ... Basic functionEdit. Modern pacemakers usually have multiple functions. The most basic form monitors the heart's native ... Thus, timing between the atrial and ventricular contractions, as well as between the septal and lateral walls of the left ... as in atrial fibrillation. The equivalent atrial pacing mode is AAI or AAIR which is the mode of choice when atrioventricular ...
Elevated right atrial pressure (>12mmHg), Moderate pulmonary hypertension, Normal systolic function, Poor diastolic function, ... Pollak, A; Falk, R H (1993-08-01). "Left ventricular systolic dysfunction precipitated by verapamil in cardiac amyloidosis". ... Vasodilators are also typically ineffective because systolic function is usually preserved in cases of RCM. Heart failure ... Patients will demonstrate normal systolic function, diastolic dysfunction, and a restrictive filling pattern. 2-dimensional and ...
Diastole ends with atrial contraction, which ejects the final 30% of blood that is transferred from the left atrium to the left ... During diastole, a normally-functioning mitral valve opens as a result of increased pressure from the left atrium as it fills ... displaystyle A(x,t)=A_{0}\left(1-[1-{\Lambda }(t)]{x \over {L}}\right)^{2}}. ∫. 0. L. p. (. x. ,. t. ). ∂. A. ∂. x. d. x. =. [ ... It is on the left side of the heart and allows the blood to flow from the left atrium into the left ventricle. ...
... preservation of systolic function, and/or rate control for atrial fibrillation with a rapid ventricular response. Heart Failure ... The first year of growth of the common foxglove produces only the stem with its long, basal leaves. During the second year of ... atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been ... Other species of Lepidoptera eat the leaves, including the lesser yellow underwing. The term digitalis is also used for drug ...
Mutations in MYH10 have been identified in patients with left atrial enlargement. NM-IIB is 228.9 kDa protein composed of 1976 ... Various functions of NM-IIB require the phosphorylation of the regulatory light chain MLC20, including cell migration and cell ... Single nucleotide polymorphisms in MYH10 were detected in patients with left atrial enlargement. MYH10 was identified to be a ... Insights into the function of NM-IIB specifically have come from studies employing transgenic animals. NM-IIB is clearly ...
Less common findings include left ventricular hypertrophy, premature atrial and ventricular contractions, atrial fibrillation, ... It can alter cardiac function, with increased heart rate, increased left ventricular mass index, increased cardiac ... Studies of thyroid function and immune parameters in patients with hyperthyroid Graves' disease in remission. Murakami M, ... January 2009). "Thyroid function abnormalities and cognitive impairment in elderly people: results of the Invecchiare in ...
Thus, timing between the atrial and ventricular contractions, as well as between the septal and lateral walls of the left ... A major step forward in pacemaker function has been to attempt to mimic nature by utilizing various inputs to produce a rate- ... as in atrial fibrillation. The equivalent atrial pacing mode is AAI or AAIR which is the mode of choice when atrioventricular ... In most cases the pacemaker is inserted in the left shoulder area where an incision is made below the collar bone creating a ...
Often, reverse remodeling, or improvement in left ventricular function, will also be seen.[citation needed] Anatomy portal Dor ... However, atrial natriuretic peptide is thought to be cardio-protective. Remodeling of the heart is evaluated by performing an ... Ventricular mass and volume increase, which together adversely affect cardiac function. Eventually, diastolic function, or the ... may actually reverse the remodeling process by reducing left ventricular volumes and improving systolic function. Early ...
Mild left atrial enlargement: the test will help to determine if the left atrium is enlarged due to alternate blood flows Right ... and functioning of left ventricle. The ECG can also be used to determine the rhythm of the heart to determine if there is an ... This is caused by blood flowing from left atrium to the right atrium causing a higher left atrial pressure and leading to ... pulmonary vascular congestion, marked left atrial enlargement: the test will help to determine if there is a sign of MS and ...
... rapid atrial and ventricular pacing, and left bundle branch block. The types of SVT associated with TIC include atrial ... Studies show that left ventricular function often improves within 1 month of treatment of the tachyarrhythmia, and ... Previously normal left ventricular ejection fraction or left ventricular systolic dysfunction out of proportion to a patient's ... In addition to decreased left ventricular ejection fraction, studies indicate that patients with TIC may have a smaller left ...
Improvements were also seen in left ventricular diastolic dimension and left atrial dimension. Patients with aortic stenosis, ... BNP is a negative indicator of cardiac function and is released during ventricular stretching. A 5 year study of Waon therapy ... Waon therapy improves many indicators of heart function including: cardiac output, stroke volume, ejection fraction, while also ... Effect of Repeated Sauna Treatment on Exercise Tolerance and Endothelial Function in Patients with Chronic Heart Failure. 2011 ...
Parallel to "diastolic function", the term "systolic function" is usually referenced in terms of the left ventricular ejection ... In terms of filling, diastolic intervals consist of early rapid filling E-waves followed by diastasis and followed by atrial ... To better understand diastolic function, it is crucial to realize that the left ventricle is a mechanical suction pump at, and ... "Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography". European Journal of ...
Left heart. *(pulmonary veins) → left atrium (atrial appendage) → mitral valve → left ventricle → aortic valve (aortic sinus ... Maceira A (2006). "Normalized Left Ventricular Systolic and Diastolic Function by Steady State Free Precession Cardiovascular ... Left atrial dimension. LA. Range 24 - 40 mm[16] Fractional shortening (FS) is the fraction of any diastolic dimension that is ... Left ventricular end-diastolic dimension. LVEDD or sometimes LVDD. The end-diastolic dimension of the left ventricle.. 48 mm,[ ...
... as a result of the inability of the left heart to pump enough blood to sustain normal organ function. In fetal life, this is ... A balloon atrial septostomy is also done. This ensures that there is enough of a connection between the two atria of the heart ... Fetal aortic stenosis impairs left ventricular development, which can lead to hypoplastic left heart syndrome. If untreated, ... a varying degree of left ventricular hypertrophy and abnormal Doppler flow characteristics in the left heart. There may be ...
... is expressed in the dorsal atrial wall, from which the primary atrial septum will emerge, and later in the septum and left ... Function[edit]. Early expression[edit]. In mice, during gastrulation on embryological day 7.5, cells fated to become ... Molecular function. • metal ion binding. • nucleic acid binding. • protein serine/threonine kinase activity. • protein binding ... Function Chick cOsr1 Expressed in intermediate and lateral plate mesoderm, developing sinus venosus of the heart, maxillary and ...
Stress EchoA stress echo, also called an exercise heart ultrasound is used to evaluate heart function by combining an exercise… ... LAACA left atrial appendage closure device can be used for atrial fibrillation patients to help prevent strokes and as an… ... A left atrial appendage closure device can be used for atrial fibrillation patients to help prevent strokes and as an ... Pooling of blood flow during atrial fibrillation in an area called the left atrial appendage can increase the risk of blood ...
This course introduces students to human anatomy and physiology and focuses on the human body as a living, functioning, ... The how-to on ischemia, injury & infarction, axis deviation, left ventricular hypertrophy, bundle branch block, and action ... EG 150: Atrial Dysrhythmias *Introduction to Atrial Dysrhythmias (p. 149). *Premature Atrial Complexes (PACs) ... Describe the structure and function of the main parts of the brain ...
... volumes of the left atrium and ventricle were calculated in 52 volunteers by 2-dimensional echocardiography. A light pen ... To obtain normal values for left atrial function noninvasively, ... To obtain normal values for left atrial function noninvasively ... End-systolic left atrial volume (mean +/- standard deviation) was 37 +/- 11.7 ml or 21 +/- 6.6 ml/m2. The change in left atrial ... These values are similar to those reported in studies in which left atrial function was calculated from contrast angiography.. ...
... decreases the intensity of spontaneous left atrial contrast, reduces the size of the left atrium, and improves left atrial ... and improves left atrial function in patient with mitral stenosis. However, left atrial mechanical functions immediately after ... Left atrial mechanical functions were evaluated before and after PMV, including left atrial passive emptying volume, LA passive ... The other left atrial volumes were not altered after PMV. The early increase in conduit volume and the decrease in left atrial ...
Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement ( ... left atrial (LA) function was assessed at baseline and after 12 months treatment using 2-D echocardiography and interpreted ... Evaluate the effects of dronedarone versus placebo on left atrial function;. *Evaluate the effects of dronedarone versus ... placebo on left atrial dimension;. *Evaluate the effects of dronedarone versus placebo on left ventricular function (LVEF, E, E ...
... and Function. Petr Kuchynka,1,2 Jana Podzimkova,1 Martin Masek,3 Lukas Lambert,3 Vladimir Cerny,3 Barbara Danek,1 and Tomas ... atrial fibrillation require the need for detailed knowledge of left atrial and pulmonary venous morphology as well of atrial ... This review article discusses the role of cardiac magnetic resonance and computed tomography in assessment of left atrial size ... The Role of Magnetic Resonance Imaging and Cardiac Computed Tomography in the Assessment of Left Atrial Anatomy, Size, ...
"Right atrial MR imaging studies of cadaveric atrial casts and comparison with right and left atrial volumes and function in ... L. Christiaens, N. Varroud-Vial, P. Ardilouze et al., "Real three-dimensional assessment of left atrial and left atrial ... Additional value of analyzing left atrial size, left atrial ejection fraction and the difference in duration of pulmonary ... "Left atrial function and scar after catheter ablation of atrial fibrillation," Heart Rhythm, vol. 5, no. 5, pp. 656-662, 2008. ...
Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis. Divya ... Background: Left atrial (LA) function by volume and strain analysis in children has been little studied. LA dysfunction related ... Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis ... Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis ...
Abstract 8124: Effect of Strong Lipophilic Statin Therapy on Left Atrial Structure and Function Assessed by Speckle Tracking ... Abstract 8124: Effect of Strong Lipophilic Statin Therapy on Left Atrial Structure and Function Assessed by Speckle Tracking ... Abstract 8124: Effect of Strong Lipophilic Statin Therapy on Left Atrial Structure and Function Assessed by Speckle Tracking ... Abstract 8124: Effect of Strong Lipophilic Statin Therapy on Left Atrial Structure and Function Assessed by Speckle Tracking ...
left atrial. LAKE. left atrial kinetic energy. LAV. left atrial volume. LAVi. left atrial volume indexed to body surface area. ... 1999) Left atrial relaxation and left ventricular systolic function determine left atrial reservoir function. Circulation 100: ... 2012) The impact of atrial fibrillation ablation left atrial function: association with baseline left atrial function. Pacing ... 2012) Left atrial minimum volume and reservoir function as correlates of left ventricular diastolic function: impact of left ...
... of LAA and left atrial spontaneous echo contrast (SEC) of left atrial appendage before ECV and after ECV 24 hours, 3 days and 1 ... function in success of electrial cardioversion (ECV) in patients with nonvalvular atrial fibrillation (NVAF), and observe the ... thrombogenic milieu Patients with atrial fibrillation should be given full anticoagulation to prevent thrombogenesis in left ... course of the recovery of LAA systaltic function Methods To test blood flow wave patterns, peak emptying velocity (PEV) ...
Left atrial myocardial function in either physiological or pathological left ventricular hypertrophy: a two-dimensional speckle ... Left atrial myocardial function in either physiological or pathological left ventricular hypertrophy: a two-dimensional speckle ...
1998) Assessment of left atrial appendage function after cardioversion of atrial fibrillation: relation to left atrial ... 1993) Altered left atrial compliance after atrial appendectomy. Influence on left atrial and ventricular filling. Circ Res 72: ... 2014) Complex left atrial appendage morphology and left atrial appendage thrombus formation in patients with atrial ... 2000) Left atrial appendage flow velocities in subjects with normal left ventricular function. Am J Cardiol 86:769-773. ...
The Left Atrial Appendage: Anatomy, Function, and Noninvasive Evaluation. Roy Beigel, Nina C. Wunderlich, Siew Yen Ho, Reza ... LAA = left atrial appendage; MDCT = multidetector computed tomography; TEE = transesophageal echocardiography; TTE = ... 3D TEE is superior to 2D TEE in visualizing the LAA orifice in relation to surrounding structures (e.g., mitral valve, left ...
Efficacy of Dofetilide in the Treatment of Atrial Fibrillation-Flutter in Patients With Reduced Left Ventricular Function. A ... Efficacy of Dofetilide in the Treatment of Atrial Fibrillation-Flutter in Patients With Reduced Left Ventricular Function. A ... There were 506 patients with atrial fibrillation/flutter (AF/Fl), congestive heart failure (CHF) or recent myocardial ... this is the largest study to date demonstrating the survival advantage of sinus rhythm among patients with AF/Fl and left ...
Mount Sinai Researchers Find Gene Therapy Improved Left Ventricular and Atrial Function in Congestive Heart Failure by up to 25 ... Heart function improved by up to 25 percent in a trial using gene therapy to reverse cardiac damage from congestive heart ... Intracoronary Delivery of Gene Vector Was Safe and Improved Heart Function in a Large Animal Model *Share ... This is the first study using a novel vector for gene therapy to improve heart function in non-ischemic heart failure. ...
Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study. ... Left atrial (LA) size, a marker of atrial structural remodeling, is associated with increased risk for atrial fibrillation (AF ... We tested the hypothesis that LA function index (LAFI), an echocardiographic index of LA structure and function, may better ... In our prospective investigation of a moderate-sized community-based sample, LAFI, a composite measure of LA size and function ...
Left information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Atrial Function, Left. Description of Atrial Function, Left. Atrial Function, Left: The hemodynamic and ... Left: *Atrial Function *Atrial *Atrial symptoms (24 causes) *Left Interesting Medical Articles:. *Symptoms of the Silent Killer ... Atrial Function, Left: Related Topics. These medical condition or symptom topics may be relevant to medical information for ...
Influence of heart rate and atrial transport on left ventricular volume and function: relation to hemodynamic changes produced ... Influence of heart rate and atrial transport on left ventricular volume and function: relation to hemodynamic changes produced ... Influence of heart rate and atrial transport on left ventricular volume and function: relation to hemodynamic changes produced ... Left ventricular ejection fraction did not change significantly with atrial pacing (from 0.65 +/- 0.02 [mean +/- standard error ...
Vmax, maximum left atrial volume; Vp, presystolic left atrial volume; Vmin, minimum left atrial volume; LAPEV, left atrial ... left atrial passive emptying fraction; CV, conduit volume; LAAEV, left atrial active emptying volume; LAAEF, left atrial active ... 1. Left atrial mechanical functions and left atrial conduction times might be impaired before the development of overt diabetes ... The left atrial volumes were calculated by the disk method. Left atrial mechanical functions were calculated. ...
LA: Left Atrium. LA Vol: Left Atrial Volume. LA C.O.: Left Atrial Cardiac Output. LVEF: Left Ventricular Ejection Fraction. ... Detection of left atrial scar and changes of cardiac function in relation to AF ablation, by 3D late gadolinium enhancement. ... Determinants of AFCA success and post-AFCA left atrial remodeling are poorly understood. Delayed Enhancement Cardiac Magnetic ... Pre and Postablation DE-CMR images of the left atrium (same patient) A. Preablation Image (0.00% LA Scar, LA Vol. of 136.1 ml ...
Left atrial function. Slovut DP, Taub CT. Immediate Improvement of Left Atrial Appendage Contractility after Transcatheter ... 1 attachment , Tags: Left atrial function, low-gradient severe aortic stenosis, paradoxical low-fl ow, transcatheter aortic ... Valve Replacement in a Patient with Paradoxical Low-Flow Low-Gradient Aortic Stenosis and Preserved Left Ventricular Function. ...
... Academic Article * ... and RT3DE were used to study 3D left atrial (LA) systolic and diastolic stroke volumes and index (LASVI, LAEDVI), emptying ... A decrease in diastolic E-wave, increased atrial kick (A-wave) with reduced E/A ratio, was noted as the pregnancy progressed. ... Background: Alteration of diastolic function is considered a sensitive means for detecting changes in the normal cardiac ...
OBJECTIVE: Our goal was to explore associations of left ventricular (LV) diffuse fibrosis with left atrial (LA) function and ... OBJECTIVE: Our goal was to explore associations of left ventricular (LV) diffuse fibrosis with left atrial (LA) function and ... keywords = "Atrial fibrillation, Fibrosis, Left atrium function, Left ventricle, P-terminal force in V1", ... OBJECTIVE: Our goal was to explore associations of left ventricular (LV) diffuse fibrosis with left atrial (LA) function and ...
Left atrial minimum volume (LAVmin), left atrial pre-atrial contraction volume (LAVp) and left atrial maximum volume (LAVmax) ... has been reported very useful in evaluating left atrial (LA) function, as well as left ventricular (LV) function. The aim of ... whereas left atrial active ejection fraction (LAAEF) and left atrial passive ejection fraction (LAPEF) were obtained from ... such as left atrial diameter (LAD), peak E and A of mitralis (E, A), E/A, end-diastolic thickness of ventricular septum (IVST d ...
  • Left atrial (LA) function by volume and strain analysis in children has been little studied. (ahajournals.org)
  • Left ventricular strain rate showed no differences between non-HF and HFPEF groups, but both groups showed differences with the HFREF group. (nih.gov)
  • No significant difference was present in S-Sr, A-Sr or global atrial strain between the normal and HT cohorts. (bmj.com)
  • It can be also estimated using various imaging techniques or other pressure readings such as PULMONARY CAPILLARY WEDGE PRESSURE (an estimate of left atrial pressure) and CENTRAL VENOUS PRESSURE (an estimate of right atrial pressure). (bioportfolio.com)
  • This propsective study aims to compare the diagnostic yield of a Personal Heart Rhythm Monitor (PHRM) with an automated cardiac event recorder (ACER) to detect paroxysmal Atrial Fibrillation PAF). (strokecenter.org)
  • The diagnostic yield of a Personal Heart Rhythm Monitor (PHRM), used for 3 months, compared to an automated cardiac event recorder (ACER), used for 1 week, to detect all episodes of paroxysmal atrial fibrillation. (strokecenter.org)
  • The diagnostic yield of a Personal Heart Rhythm Monitor (PHRM), used for 3 months, compared to an automated cardiac event recorder (ACER), used for 1 week, to detect prolonged episodes of paroxysmal atrial fibrillation (defined as greater than 12 hours). (strokecenter.org)
  • Numerous studies have clearly demonstrated the prognostic value of left atrial volume for long-term outcome. (hindawi.com)
  • In sequential Cox proportional hazards models, A -wave, E / A ratio, and GLS were significantly associated with outcomes, independent of age, sex, and cardiac resynchronization therapy defibrillator or left bundle branch block. (edu.au)
  • Long-term outcomes of secondary atrial fibrillation in the community: the Framingham Heart Study. (medscape.com)
  • This review article discusses the role of cardiac magnetic resonance and computed tomography in assessment of left atrial size, its normal and abnormal morphology, and function. (hindawi.com)
  • The interatrial and left atrial electromechanical delay were significantly longer in prediabetic group compared to the controls. (kjim.org)
  • Information on updates and common medical emergencies was significantly more important to respondents than materials on common illnesses, finding a PCP, or ED function. (physiciansweekly.com)
  • In a subgroup analysis between racial groups, minority groups had significantly less knowledge of the definitions of triage and teaching hospitals, but wanted significantly more information on ED function. (physiciansweekly.com)
  • There was no between-group difference in the increase in the overall patient population, but among those who were in the upper three quartiles of left ventricular hypertrophy at baseline, the increase was significantly greater with placebo (50% versus 16%, P =0.041). (medpagetoday.com)
  • Embodiments of this invention relate to a method and device for improving cardiac function. (google.ca)
  • 4 However, Gurvich and Yuniev 2 3 acknowledged that defibrillation had a suppressive effect on cardiac function, which may be injurious and thus necessitated limiting the magnitude of shock current. (ahajournals.org)
  • The left atrial appendage (LAA) in the setting of non-valvular atrial fibrillation (NVAF) is the predominant location for intracardiac thrombus formation. (bioportfolio.com)
  • This, in turn, can lead to development of thrombus, most commonly in the left atrial appendage. (medscape.com)
  • Moreover, the release of such biologically active molecules also promotes endothelial function impairment, disturbs the haemostatic and fibrinolytic systems, and produces alterations in platelet function affecting the initiation, progression, and stabilization of thrombus formation upon atherosclerotic plaque rupture. (diva-portal.org)