The hemodynamic and electrophysiological action of the LEFT ATRIUM.
The hemodynamic and electrophysiological action of the HEART ATRIA.
The hemodynamic and electrophysiological action of the RIGHT ATRIUM.
The chambers of the heart, to which the BLOOD returns from the circulation.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Echocardiography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.
Surgical excision (total or partial) of a portion of the pericardium. Pericardiotomy refers to incision of the pericardium.
An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)
Contractile activity of the MYOCARDIUM.
Examinations used to diagnose and treat heart conditions.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
The hemodynamic and electrophysiological action of the HEART VENTRICLES.
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.
Intellectual or mental process whereby an organism obtains knowledge.
Disturbances in mental processes related to learning, thinking, reasoning, and judgment.
A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).
The time span between the beginning of physical activity by an individual and the termination because of exhaustion.
Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.
The production of adhesions between the parietal and visceral pleura. The procedure is used in the treatment of bronchopleural fistulas, malignant pleural effusions, and pneumothorax and often involves instillation of chemicals or other agents into the pleural space causing, in effect, a pleuritis that seals the air leak. (From Fishman, Pulmonary Diseases, 2d ed, p2233 & Dorland, 27th ed)
Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.
Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed)
Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.
Pathological processes of the LIVER.
The restoration of the sequential order of contraction and relaxation of the HEART ATRIA and HEART VENTRICLES by atrio-biventricular pacing.
Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.
A complex of ferric oxyhydroxide with dextrans of 5000 to 7000 daltons in a viscous solution containing 50 mg/ml of iron. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)
A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
Cell surface proteins that bind ATRIAL NATRIURETIC FACTOR with high affinity and trigger intracellular changes influencing the behavior of cells. They contain intrinsic guanylyl cyclase activity.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
A PEPTIDE of 22 amino acids, derived mainly from cells of VASCULAR ENDOTHELIUM. It is also found in the BRAIN, major endocrine glands, and other tissues. It shares structural homology with ATRIAL NATRIURETIC FACTOR. It has vasorelaxant activity thus is important in the regulation of vascular tone and blood flow. Several high molecular weight forms containing the 22 amino acids have been identified.

A comparison of an A1 adenosine receptor agonist (CVT-510) with diltiazem for slowing of AV nodal conduction in guinea-pig. (1/734)

1. The purpose of this study was to compare the pharmacological properties (i.e. the AV nodal depressant, vasodilator, and inotropic effects) of two AV nodal blocking agents belonging to different drug classes; a novel A1 adenosine receptor (A1 receptor) agonist, N-(3(R)-tetrahydrofuranyl)-6-aminopurine riboside (CVT-510), and the prototypical calcium channel blocker diltiazem. 2. In the atrial-paced isolated heart, CVT-510 was approximately 5 fold more potent to prolong the stimulus-to-His bundle (S-H interval), a measure of slowing AV nodal conduction (EC50 = 41 nM) than to increase coronary conductance (EC50 = 200 nM). At concentrations of CVT-510 (40 nM) and diltiazem (1 microM) that caused equal prolongation of S-H interval (approximately 10 ms), diltiazem, but not CVT-510, significantly reduced left ventricular developed pressure (LVP) and markedly increased coronary conductance. CVT-510 shortened atrial (EC50 = 73 nM) but not the ventricular monophasic action potentials (MAP). 3. In atrial-paced anaesthetized guinea-pigs, intravenous infusions of CVT-510 and diltiazem caused nearly equal prolongations of P-R interval. However, diltiazem, but not CVT-510, significantly reduced mean arterial blood pressure. 4. Both CVT-510 and diltiazem prolonged S-H interval, i.e., slowed AV nodal conduction. However, the A1 receptor-selective agonist CVT-510 did so without causing the negative inotropic, vasodilator, and hypotensive effects associated with diltiazem. Because CVT-510 did not affect the ventricular action potential, it is unlikely that this agonist will have a proarrythmic action in ventricular myocardium.  (+info)

Identification and characterization of multiple subtypes of muscarinic acetylcholine receptors and their physiological functions in canine hearts. (2/734)

M2 receptors have long been believed to be the only functional subtype of muscarinic acetylcholine receptor (mAChR) in the heart, although recent studies have provided evidence for the presence of other subtypes. We performed a detailed study to clarify this issue. In the presence of tetramethylammonium (1 microM to 10 mM), a novel K+ current with both delayed rectifying and inward rectifying properties (IKTMA) was activated in single canine atrial myocytes. 4-Aminopyridine (0.05-2 mM) also induced a K+ current (IK4AP) with characteristics similar to but distinct from those of IKTMA. Both IKTMA and IK4AP were abolished by 1 microM atropine. IK4AP, but not IKTMA, was minimized by treatment with pertussis toxin. IKTMA was markedly decreased by 4-diphenylacetoxy-N-methylpiperidine methiodide (a selective antagonist for M3 subtype) but was not altered by pirenzepine (for M1), methoctramine (for M2), and tropicamide (for M4). Tropicamide substantially reduced IK4AP, but the antagonists for other mAChR subtypes had no effects on IK4AP. By comparison, IKACh (ACh-induced K+ current) was significantly depressed by methoctramine but was unaltered by other antagonists. Results from displacement binding of [methyl-3H]N-scopolamine methyl chloride with pirenzepine, methoctramine, 4-diphenylacetoxy-N-methylpiperidine methiodide, or tropicamide revealed the coexistence of multiple mAChR subtypes in canine atrium. Cloning of cDNA fragments and detection of mRNAs coding for M2, M3, and M4 provided further supporting evidence. Our results suggest that 1) multiple subtypes of mAChRs (M2/M3/M4) coexist in the dog heart and 2) different subtypes of mAChRs are coupled to different K+ channels. Our findings represent the first functional evidence for the physiological role of cardiac M3 and M4 receptors.  (+info)

Regional differences in the recovery course of tachycardia-induced changes of atrial electrophysiological properties. (3/734)

BACKGROUND: Regional differences in recovery of tachycardia-induced changes of atrial electrophysiological properties have not been well studied. METHODS AND RESULTS: In the control group (5 dogs), atrial effective refractory period (AERP) and inducibility of atrial fibrillation (AF) were assessed before and every 4 hours for 48 hours after complete atrioventricular junction (AVJ) ablation with 8-week VVI pacing. In experimental group 1 (15 dogs), AERP and inducibility of AF were assessed before and after complete AVJ ablation with 8-week rapid right atrial (RA) pacing (780 bpm) and VVI pacing. In experimental group 2 (7 dogs), AERP and inducibility of AF were assessed before and after 8-week rapid left atrial (LA) pacing and VVI pacing. AERP and inducibility and duration of AF were obtained from 7 epicardial sites. In the control group, atrial electrophysiological properties obtained immediately and during 48-hour measurements after pacing did not show any change. In the 2 experimental groups, recovery of atrial electrophysiological properties included a progressive recovery of AERP shortening, recovery of AERP maladaptation, and decrease of duration and episodes of reinduced AF. However, recovery of shortening and maladaptation of AERP and inducibility of AF was slower at the LA than at the RA and Bachmann's bundle. CONCLUSIONS: The LA had a slower recovery of tachycardia-induced changes of atrial electrophysiological properties, and this might play a critical role in initiation of AF.  (+info)

Rate-dependent blockade of a potassium current in human atrium by the antihistamine loratadine. (4/734)

The antihistamine loratadine is widely prescribed for the treatment of symptoms associated with allergies. Although generally believed to be free of adverse cardiac effects, there are a number of recent reports suggesting that loratadine use may be associated with arrhythmias, in particular atrial arrhythmias. Nothing is known regarding the potassium channel blocking properties of loratadine in human cardiac cells. Using the whole-cell patch clamp technique, the effects of loratadine on the transient outward K current (Ito), sustained current (Isus), and current measured at -100 mV (IK1 and Ins), the major inward and outward potassium currents present in human atrial myocytes, were examined in order to provide a possible molecular mechanism for the observed atrial arrhythmias reported with loratadine use. Loratadine rate-dependently inhibited Ito at therapeutic concentrations with 10 nM loratadine reducing Ito amplitude at a pacing rate of 2 Hz by 34.9+/-6.0%. In contrast, loratadine had no effect on either Isus or current measured at -100 mV. These results may provide a possible mechanism for the incidences of supraventricular arrhythmias reported with the use of loratadine.  (+info)

Inhibitory effects of aprindine on the delayed rectifier K+ current and the muscarinic acetylcholine receptor-operated K+ current in guinea-pig atrial cells. (5/734)

In order to clarify the mechanisms by which the class Ib antiarrhythmic drug aprindine shows efficacy against atrial fibrillation (AF), we examined the effects of the drug on the repolarizing K+ currents in guinea-pig atrial cells by use of patch-clamp techniques. We also evaluated the effects of aprindine on experimental AF in isolated guinea-pig hearts. Aprindine (3 microM) inhibited the delayed rectifier K+ current (IK) with little influence on the inward rectifier K+ current (IK1) or the Ca2+ current. Electrophysiological analyses including the envelope of tails test revealed that aprindine preferentially inhibits IKr (rapidly activating component) but not IKs (slowly activating component). The muscarinic acetylcholine receptor-operated K+ current (IK.ACh) was activated by the extracellular application of carbachol (1 microM) or by the intracellular loading of GTPgammaS. Aprindine inhibited the carbachol- and GTPgammaS-induced IK.ACh with the IC50 values of 0.4 and 2.5 microM, respectively. In atrial cells stimulated at 0.2 Hz, aprindine (3 microM) per se prolonged the action potential duration (APD) by 50+/-4%. The drug also reversed the carbachol-induced action potential shortening in a concentration-dependent manner. In isolated hearts, perfusion of carbachol (1 microM) shortened monophasic action potential (MAP) and effective refractory period (ERP), and lowered atrial fibrillation threshold. Addition of aprindine (3 microM) inhibited the induction of AF by prolonging MAP and ERP. We conclude the efficacy of aprindine against AF may be at least in part explained by its inhibitory effects on IKr and IK.ACh.  (+info)

Aryl propanolamines: comparison of activity at human beta3 receptors, rat beta3 receptors and rat atrial receptors mediating tachycardia. (6/734)

1. The in vitro activity of four aryl propanolamines was compared to two prototypic beta3 receptor agonists, CGP 12177 and CL316243 at the human beta3 receptor, the rat beta3 receptor in the stomach fundus and receptors mediating atrial tachycardia. 2. L-739,574 was the most potent (EC50 = 9 nM) and selective agonist at the human beta3 receptor with high maximal response (74% of the maximal response to isoproterenol). 3. A phenol-biaryl ether analogue possessed modest affinity for the human beta3 receptor (EC50 = 246 nM), but was highly efficacious with a maximal response 82% of the maximal response to isoproterenol. The other derivatives were intermediate in potency with low maximal responses. 4. These agonists at the human beta3 receptor did not activate the rat beta3 receptor in the rat stomach fundus. In fact, the aryl propanolamines (10(-6) M) inhibited CL316243-induced activation of the rat beta3 receptor. Thus, agonist activity at the human beta3 receptor translated into antagonist activity at the rat beta3 receptor. 5. L739,574 and the phenol biaryl ether increased heart rate via beta1 receptors. 6. Although CGP12177 produced atrial tachycardia, neither the indole sulphonamide nor biphenyl biaryl ether did, although both had high affinity for the human beta3 receptor. Thus, the atrial tachycardic receptor was not identical to the human beta3 receptor. 7. These studies (a) characterized four aryl propanolamines with high affinity at the human beta3 receptor, (b) found that they were antagonists at the rat beta3 receptor, an observation with profound implications for in vivo rat data, and (c) established that the rodent atrial non-beta1, beta2 or beta3 tachycardic receptor was also unrelated to the human beta3 receptor.  (+info)

Altered kinetics of contraction of mouse atrial myocytes expressing ventricular myosin regulatory light chain. (7/734)

To investigate the role of myosin regulatory light chain isoforms as a determinant of the kinetics of cardiac contraction, unloaded shortening velocity was determined by the slack-test method in skinned wild-type murine atrial cells and transgenic cells expressing ventricular regulatory light chain (MLC2v). Transgenic mice were generated using a 4.5-kb fragment of the murine alpha-myosin heavy chain promoter to drive high levels of MLC2v expression in the atrium. Velocity of unloaded shortening was determined at 15 degrees C in maximally activating Ca2+ solution (pCa 4.5) containing (in mmol/l) 7 EGTA, 1 free Mg2+, 4 MgATP, 14.5 creatine phosphate, and 20 imidazole (ionic strength 180 mmol/l, pH 7.0). Compared with the wild type (n = 10), the unloaded shortening velocity of MLC2v-expressing transgenic murine atrial cells (n = 10) was significantly greater (3.88 +/- 1.19 vs. 2.51 +/- 1.08 muscle lengths/s, P < 0.05). These results provide evidence that myosin light chain 2 regulates cross-bridge cycling rate. The faster rate of cycling in the presence of MLC2v suggests that the MLC2v isoform may contribute to the greater power-generating capabilities of the ventricle compared with the atrium.  (+info)

Mapping of atrial activation with a noncontact, multielectrode catheter in dogs. (8/734)

BACKGROUND: Endocardial mapping of sustained arrhythmias has traditionally been performed with a roving diagnostic catheter. Although this approach is adequate for many tachyarrhythmias, it has limitations. The purpose of this study was to evaluate a novel noncontact mapping system for assessing atrial tachyarrhythmias. METHODS AND RESULTS: The mapping system consists of a 9F multielectrode-array balloon catheter that has 64 active electrodes and ring electrodes for emitting a locator signal. The locator signal was used to construct a 3-dimensional right atrial map; it was independently validated and was highly accurate. Virtual electrograms were calculated at 3360 endocardial sites in the right atrium. We evaluated right atrial activation by positioning the balloon catheter in the mid right atrium via a femoral venous approach. Experiments were performed on 12 normal mongrel dogs. The mean correlation coefficient between contact and virtual electrograms was 0.80+/-0.12 during sinus rhythm. Fifty episodes of atrial flutter induced in 11 animals were evaluated. In the majority of experiments, complete or almost complete reentrant circuits could be identified within the right atrium. Mean correlation coefficient between virtual and contact electrograms was 0.85+/-0.17 in atrial flutter. One hundred fifty-six episodes of pacing-induced atrial fibrillation were evaluated in 11 animals. Several distinct patterns of right atrial activation were seen, including single-activation wave fronts and multiple simultaneous-activation wave fronts. Mean correlation coefficient between virtual and contact electrograms during atrial fibrillation was 0.81+/-0.18. The accuracy of electrogram reconstruction was lower at sites >4.0 cm from the balloon center and at sites with a high spatial complexity of electrical activation. CONCLUSIONS: This novel noncontact mapping system can evaluate conduction patterns during sinus rhythm, demonstrate reentry during atrial flutter, and describe right atrial activation during atrial fibrillation. The accuracy of electrogram reconstruction was good at sites <4.0 cm from the balloon center, and thus the system has the ability to perform high-resolution multisite mapping of atrial tachyarrhythmias in vivo.  (+info)

Looking for atrial standstill? Find out information about atrial standstill. An interval in the cycle of a variable star during which its brightness remains nearly constant Explanation of atrial standstill
Sarcolipin (SLN), a key regulator of sarcoplasmic reticulum Ca2+ ATPase (SERCA) plays an important role in atrial Ca2+ homeostasis and therefore suggested as a possible candidate for genetic cause of atrial arrhythmias. The aim of this study was to find if the SLN gene has a causative role in human atrial standstill, a rare lethal disorder of atrial musculature. Genomic DNA from formalin fixed atrial tissue and fibroblast from deceased newborn with atrial standstill were used as templates in PCR reaction to amplify the coding exon of SLN and screened for mutation. DNA sequencing identified ATG → ATA transition mutation at the translation initiation site in 20% of clones from atrial DNA. There were no coding region mutations identified in clones obtained from fibroblast tissues. To validate our findings, we designed mutant specific PCR screening method and amplified the genomic DNA from control atria and atria and fibroblast tissues of fetal atrial standstill. PCR amplification occurs only with ...
Results Atrial trabeculae harvested from diabetic (N=13 patients) and non-diabetic control patients (N=20 patients) were demonstrated to recover 24.5%±2.4% and 29.3%±1.3% of baseline contractile function, respectively. Prior treatment of patients with RIPC1 increased the recovery of function in both non-diabetic (50.4%±1.9%; p,0.05) and diabetic (41.6%±1.9%; p,0.05) patients. Interestingly, the stronger RIPC2 stimulus resulted in a greater recovery of function in both non-diabetic (59.3%±1.9%; p,0.05) and diabetic (50.7%±2.1%; p,0.05) patients. As a positive control direct hypoxic preconditioning (HPC) of atrial trabeculae also improved the recovery of function (56.4%±1.8% with HPC vs 27.5%±1.7% in control; N=10 patients; p,0.05). The administration of the MEK-Erk1/2 inhibitors U0126 and PD98059 at the onset of reperfusion abrogated the protective effect in both non-diabetic (30.9%±0.8% U0126 and 31.3%±0.8% PD98059; p,0.05) and diabetic (28.6%±0.9% U0126 and 30.0%±1.2% PD98059; ...
The natural history of adults with an atrial septal defect (ASD) and chronic right atrial (RA) volume overload is characterized by an increased risk for the development of atrial arrhythmias that appears to be minimally altered by ASD closure.1 Although surgical lines of block may form the substrate for scar-related atrial macroreentry after surgical ASD repair,2 there is limited information concerning the impact of chronic RA stretch and volume overload on atrial electrophysiology in ASD patients.. Animal studies of chronic atrial enlargement have demonstrated an increased vulnerability to atrial arrhythmias,3,4 and atrial electrical remodeling (ER) has been described in response to chronic atrial stretch.3,5 Although initial studies of atrial ER focused on tachycardia-induced changes in atrial refractoriness for the promotion of atrial fibrillation (AF),6 more recent studies concerning chronic atrial stretch and ER have emphasized the contribution of heterogeneous disturbances in atrial ...
Is Left Atrial Dilatation a common side effect of Sevikar? View Left Atrial Dilatation Sevikar side effect risks. Male, 67 years of age, weighting 176.4 lb, was diagnosed with hypertension and took Sevikar 20/5mg,oral. Patient was hospitalized.
, Human Atrium, right (hypertension) tissue lysate, GTX25590, Applications: ELISA, IP, WB; ELISA, Immunoprecipitation, Western Blot (WB); CrossReactivity:
Eesti Teadusinfosüsteem koondab informatsiooni teadus- ja arendusasutuste, teadlaste, teadusprojektide ning erinevate teadustegevuste tulemuste kohta.
A stunningly preserved fossil fern from the Jurassic Period reveals that the plant has remained in evolutionary stasis since then.
The Saddledome is the oldest barn. While the NHL and the city fight over who pays to replace it, Chris Epp tells us about the fans whove been benched while they wait for a decision…
Results: AF was induced with high producibility using burst pacing to the atrium. AF lasted for 349 s in the AVS group, which was about 40 times longer than that in sham-operated group (8 s). The duration of AF in the AVS+Pyr3 group (42 s) was shorter than that in the AVS group. There was no significant difference in the atrial effective refractory period among the 3 groups. The duration of P wave of the ECG, roughly reflecting intra-atrial conduction time, was 26 ms in the AVS group, which was longer than that in the sham-operated group (17 ms). The P wave duration in the AVS+Pyr3 group (22 ms) was shorter than that in the AVS group. The atrial weights in the AVS group were about 4.3 times greater than that in the sham-operated group. The atrial weights in the AVS+Pyr3 group were less great than those in the AVS group ...
A mass flock of sheep was recently moved across town bringing traffic to a standstill in Cedar City, Utah.Bystander Bryan Cosby was driving home from school when police began to divert traffic and he had to pull off into a parking lot.
Premature atrial contraction is an early beat of the hearts upper chamber (atrium). It may feel like the heart skipped a beat. (See also palpitations.) ...
We are no ordinary property company. Buildings are naturally the basis of our operations, but our heart actually lies with the environments that...
We offer Embedded Intelligent System Projects for students in takeoffgroup,tirupati.like A Cooperative Train Control Model for Energy Saving & etc
TY - JOUR. T1 - Localization of atrial natriuretic peptide in normal human atrial tissue by immunoelectron microscopy. AU - Wei, Chi Ming. AU - Hukee, Margaret. AU - McGregor, Christopher G.A.. AU - Burnett, John C.. PY - 1993/12/1. Y1 - 1993/12/1. N2 - The study shows that atrial matriuretic peptide (ANP) is localized to secretory granules in normal human atrial tissue. This extends our understanding to the normal human of the biology of atrial regulation of this significant peptide of cardiac origin.. AB - The study shows that atrial matriuretic peptide (ANP) is localized to secretory granules in normal human atrial tissue. This extends our understanding to the normal human of the biology of atrial regulation of this significant peptide of cardiac origin.. UR - http://www.scopus.com/inward/record.url?scp=0027705543&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0027705543&partnerID=8YFLogxK. M3 - Conference article. AN - SCOPUS:0027705543. SP - 316. EP - 317. JO - ...
TY - JOUR. T1 - Sarcoplasmic reticulum Ca2+ regulatory protein gene expression in human right atrium under hemodynamic overload. AU - Sadamatsu, Kenji. AU - Urabe, Yoshitoshi. AU - Tsutsui, Hiroyuki. AU - Tagawa, Hirofumi. AU - Maruoka, Fumio. AU - Igarashi-Saito, Keiko. AU - Takeda, Kotaro. AU - Kawachi, Yoshito. AU - Yasui, Hisataka. AU - Takeshita, Akira. PY - 1999/1/1. Y1 - 1999/1/1. N2 - Sarcoplasmic reticulum (SR) Ca2+-adenosine triphosphatase (ATPase) mRNA expression is reduced in the failing human myocardium. However, it is not known whether SR Ca2+-regulatory protein gene expression is altered in human myocardial tissue subjected to pressure overload or volume overload. We sought to determine whether SR Ca2+-regulatory protein gene expression is altered in human atrial tissue subjected to mechanical overload. We obtained right atrial myocardial tissue (about 250 mg) at open-heart surgery from three groups of patients: no hemodynamic overload to the right atrium (control group; 12 ...
We read with great interest the paper by Carluccio et al. (1) regarding the impact of left ventricular (LV) remodeling on the response to cardiac resynchronization therapy (CRT). In this elegant study, the authors performed a comprehensive assessment of LV function, showing that extensive LV remodeling at baseline is associated with poor improvement after CRT.. We wish to raise an essential issue, which may be of keen interest to the readers.. In recent years, there has been growing interest in the potential impact of CRT on atrial function, but the state of knowledge in this field is still controversial and unsettled (2-4). In the paper by Carluccio et al. (1) several baseline data concerning atrial function are presented (left atrial volume index and mitral regurgitation severity), but unfortunately there is no information related to CRT response. We believe that their excellent echocardiographic data could also be useful to better understand another debated issue (i.e., the effect of CRT on ...
TY - JOUR. T1 - Antegrade late diastolic arterial blood flow in the fetus. T2 - Insight into fetal atrial function. AU - Howley, Lisa W.. AU - Yamamoto, Yuka. AU - Sonesson, Sven Erik. AU - Sekar, Priya. AU - Jain, Venu. AU - Motan, Tarek. AU - Savard, Winnie. AU - Wagner, Brandie D.. AU - Trines, Jean. AU - Hornberger, Lisa K.. PY - 2013/6. Y1 - 2013/6. N2 - Objective: The purpose of this study was to examine the presence and frequency of antegrade late diastolic arterial blood flow (ALDAF) in the fetus and to determine its contribution to cardiac output. Study Design: We evaluated the presence of ALDAF in 457 fetal and 21 postnatal echocardiograms. The timing of ALDAF to the ventricular systolic Doppler recording (ALDAF-V) was compared with the mechanical atrioventricular interval and, in neonates, the electrical PR interval. Velocity time integrals of ALDAF and the ventricular systolic Doppler signals were measured, and the percent contribution of ALDAF was calculated. Results: ALDAF was ...
Several anti-arrhythmic agents, which are used in treatment of AF, exist. However, the efficacy of these drugs still can be improved. Furthermore, some of them are associated with a wide range of adverse side effects. Therefore, the mechanisms of action of these agents have to be better understood and still can be optimized.. Dronedarone is an anti-arrhythmic agent used in the treatment of AF by maintaining sinus rhythm. It is a derivative of amiodarone and has been developed to reduce the side effects as e.g. thyroid toxicity of its precursor compound.. The aim of this work is to integrate the effects of dronedarone into a model of atrial electrophysiology. In this way, the mechanism of action, i.e. the anti-arrhythmic effects of this agent should be better understood. In previous work, the effects of amiodarone were already integrated into an atrial cell model. Finally, a comparison of both agents and their impact on healthy and electrically remodeled tissue shall be carried out. ...
Introduction: The development of improved diagnosis, management, and treatment strategies for human atrial fibrillation (AF) is a significant and important challenge in order to improve quality of life for millions and reduce the substantial social-economic costs of the condition. As a complex condition demonstrating high variability and relation to other cardiac conditions, the study of AF requires approaches from multiple disciplines including single-cell experimental electrophysiology and computational modeling. Models of human atrial cells are less well parameterized than those of the human ventricle or other mammal species, largely due to the inherent challenges in patch clamping human atrial cells. Such challenges include, frequently, unphysiologically depolarized resting potentials and thus injection of a compensatory hyperpolarizing current, as well as detecting certain ion currents which may be disrupted by the cell isolation process. The aim of this study was to develop a laboratory specific
Purpose: The evolution of ARVC is more diffuse right ventricle (RV) involvement and, sometimes, left ventricular(LV) abnormalities, that may result in heart failure. We evaluated the potential utility of two-dimensional (2D) Strain-Strain rate (S-SR) and 3D echocardiography to quantitatively assess
Stakeholders at the Roma Saleyards put their emergency national stock standstill procedures to the test recently during a simulated outbreak of foot and mouth disease.
Traffic came to a standstill on U.S. 63 between Ashland and Jefferson City Friday morning. Southern Boone County Fire Protection District said a middle aged woman was driving to work on the highway when she got dizzy and swerved into an 8 foot ditch.
We know the atrial pressure wave forms vary between right and left atrium .In the right atrium a waves are prominent and taller than v waves, while the reverse is true in left atrium . The reasons for tall left atrial v waves are V waves are passive atrial filling waves and are timed during ventricular…
Shafiq, a shikarawala, is being forced to sell off some of his belongings to pay the fees of his son studying MBA in a Pune college while hawker Rafiq is mortgaging his wifes jewellery to feed his family.
The continued suspension of markets, shows and the imposition of a 20-day standstill on all movements has left me vexed. On the one hand the EU is, from th
They are activated if the initial speed is greater than 50 km/h and Brake Assist BAS has recognised an emergency braking situation; or the brake pressure is more than 75 percent of the maximum. In addition, the hazard warning lights are activated when the vehicle comes to a standstill if the speed prior to braking exceeded 70 km/h ...
If we continue to focus solely on the sinner/saint duality in our person and conduct, while ignoring the raging opposition between the Pharisee and the child, spiritual growth will come to an abrupt standstill.~~Brennan Manning
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TY - JOUR. T1 - Measurement of funny current (I(f)) channel mRNA in human atrial tissue. T2 - Correlation with left atrial filling pressure and atrial fibrillation. AU - Lai, Ling Ping. AU - Su, Ming Jai. AU - Lin, Jiunn Lee. AU - Tsai, Chang Her. AU - Lin, Fang Yue. AU - Chen, Yih Sharng. AU - Hwang, Juey Jen. AU - Stephen Huang, Shoei K.. AU - Tseng, Yung Zu. AU - Lien, Wen Pin. PY - 1999/1/1. Y1 - 1999/1/1. N2 - Introduction: The funny current (I(f)) contributes to phase IV spontaneous depolarization in cardiac pacemaker tissue. Enhanced I(f) activity in myocardial tissue may lead to increased automaticity and therefore tachyarrhythmia. We measured the amount of I(f) activity in the messenger ribonucleic acid (mRNA) in human atrial tissue and correlated the mRNA amount to left atrial filling pressure and atrial fibrillation (AF). Methods and Results: A total of 34 patients undergoing open heart surgery were included (15 men and 19 women, aged 55 ± 10 years). Atrial tissue was obtained from ...
TY - JOUR. T1 - Associations of electrocardiographic P-wave characteristics with left atrial function, and diffuse left ventricular fibrosis defined by cardiac magnetic resonance. T2 - The PRIMERI study. AU - Win, Theingi Tiffany. AU - Venkatesh, Bharath Ambale. AU - Volpe, Gustavo J.. AU - Mewton, Nathan. AU - Rizzi, Patricia. AU - Sharma, Ravi K.. AU - Strauss, David G.. AU - Lima, Joao A.. AU - Tereshchenko, Larisa G.. PY - 2015/1/1. Y1 - 2015/1/1. N2 - BACKGROUND: Abnormal P-terminal force in lead V1 (PTFV1) is associated with an increased risk of heart failure, stroke, atrial fibrillation, and death. OBJECTIVE: Our goal was to explore associations of left ventricular (LV) diffuse fibrosis with left atrial (LA) function and electrocardiographic (ECG) measures of LA electrical activity. METHODS: Patients without atrial fibrillation (n = 91; mean age 59.5 years; 61.5% men; 65.9% white) with structural heart disease (spatial QRS-T angle ≥105° and/or Selvester QRS score ≥5 on ECG) but LV ...
To obtain normal values for left atrial function noninvasively, volumes of the left atrium and ventricle were calculated in 52 volunteers by 2-dimensional echocardiography. A light pen digitizing and computation system, controlled by a microprocessor
Blocked premature atrial contractions (BPACs) are considered a type cardiac bradyarrhythmia and if occurring in utero is classified under a fetal bradyarrhythmia. Pathology It is seen when a premature atrial contraction occurs very early on and...
Atrium Heart Atrium heart atria of the heart function ideas. Atrium heart chambers ideas. Atrium heart atrial fibrillation harvard health. Atrium Heart Atrium heart overview of atrial fibrillation free. Atrium heart atrium advanced cardio services download. Atrium heart about atrial fibrillation atrium vs ventricle anatomy. Atrium Heart ...
BioAssay record AID 467401 submitted by ChEMBL: Negative chronotropic activity in guinea pig right atrium assessed as decrease in atrial rate at 50 uM relative to control.
Cases come from all over the world. Patient identifiers have been redacted or patient consent has been obtained. The contents of this site have not been reviewed nor approved by Hennepin County Medical Center and any views or opinions expressed herein do not necessarily reflect the views or opinions of Hennepin County Medical Center ...
http://www.bbc.com/news/uk-politics-41585430 So, still no movement in those negotiations. I read early this week that British politicians still think its the EUs turn to put an acceptable offer on the table. I wonder when they will realise that the EU doesnt have to do jack shit. The disorganisation in the British Government is going to cost them. How much longer can May be PM before people realise shes incompetent? Also, British legal experts say they can still cancel the whole
A government shutdown could occur at the end of this month. This years appropriations process is at a standstill, and disagreement over further economic relief and other issues may derail even a
Im really getting pissed off now at how slowly my weight loss is going, ie so slowly that its at a standstill or even occasionally in reverse. When you have a lot to lose its supposed to fall off really quickly at first, right? Not in my case it would seem. I had a thyroid…
Many people have cramps during their menstruation-- its just an uncomfortable side effect. But for some people that condition can be incredibly painful- to the point of unbearable. They may be unable to get out of bed or go to work. Their life turns to a standstill while they lay curled up in their bed.…
Talks between both parties came to a standstill in October after Philippine negotiators said they needed more time to study issues
First came the dot-com bust, wiping out their big-spending Silicon Valley customers.Then, the sobering attacks of Sept. 11 almost brought their sales to a standstill.Even now, with a sluggish
Atrium refers to either of the hearts two upper chambers in which blood collects before being passed to the ventricles, or the hearts lower chambers.. ...
The Royal College of Physicians (RCP) today announced its intent to deliver a new national clinical audit programme across England, Scotland and Wales that will improve the quality of care and outcomes for patients with asthma and COPD. ...
The ionic mechanisms underlying many important properties of the human atrial action potential are poorly understood. Using specific formulations of the K+, Na+ and Ca2+ currents based on experimental data recorded from human atrial myocytes, along with representations of pump, exchange and background currents, Marc Courtemanche, Rafael J. Ramirez and Stanley Nattel developed a mathematical model of the action potential (see the figure below). This mathematical model builds mostly on the classical work of Luo and Rudy (see The Luo-Rudy Ventricular Model II (dynamic), 1994). Courtemanche et al effectively develop a working model of the human atrial action potential from the Luo-Rudy model which is based on guinea pig ventricular cells. Their primary goal was to develop a useful model of the action potential from which they could gain insights into experimental observations made on human atrial cells and tissues and make predictions regarding the behaviour of these cells under previously untested ...
Looking for online definition of atrial systole in the Medical Dictionary? atrial systole explanation free. What is atrial systole? Meaning of atrial systole medical term. What does atrial systole mean?
Background Atrial stretch is considered to are likely involved in the introduction of atrial fibrillation (AF). on the LA appendage area in 24 from the 40 sufferers (60%) with Rabbit polyclonal to ABCG5. persistent AF (p=0.0006). In multivariate evaluation LA pressure was the just unbiased predictor of DFmax in the LA appendage (p=0.04 OR 1.41 95 CI 1.02 to at least one 1.94). Conclusions Higher LA pressure in sufferers with consistent AF means that these sufferers are more susceptible to stretch-related remodeling than patients with paroxysmal AF. The DF of IKK-2 inhibitor VIII AF was directly related to LA pressure in patients with persistent AF. This suggests that atrial stretch may contribute to the maintenance of AF in humans by stabilizing high frequency sources. AF was defined as the time IKK-2 inhibitor VIII period extending from the date of recurrence to the date of the ablation procedure. Patients with paroxysmal AF4 who presented to the laboratory in AF served as a comparison group ...
Brodde OE, Karad K, Zerkowski HR, Rohm N, Reidemeister JC (1983). „Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding. Circulation Research. 53 (6): 752-758. PMID 6139182 ...
Oct. 3, 2014 - Wieland Electric has expanded its product line of machine safety devices with a sensorless standstill monitor compatible with all types of
Sugimoto T, Robinet S, Dulgheru R, Bernard A, Ilardi F, Contu L, Addetia K, Caballero L, Kacharava G, Athanassopoulos GD, Barone D, Baroni M, Cardim N, Hagendorff A, Hristova K, Lopez T, de la Morena G, Popescu BA, Penicka M, Ozyigit T, Rodrigo Carbonero JD, van de Veire N, Von Bardeleben RS, Vinereanu D, Zamorano JL, Go YY, Marchetta S, Nchimi A, Rosca M, Calin A, Moonen M, Cimino S, Magne J, Cosyns B, Galli E, Donal E, Habib G, Esposito R, Galderisi M, Badano LP, Lang RM, Lancellotti P. Echocardiographic reference ranges for normal left atrial function parameters: results from the EACVI NORRE study. Eur Heart J Cardiovasc Imaging. 2018 06 01; 19(6):630-638 ...
ATRIAL REPOLARIZATION IS NOT SEEN BECAUSE IT OCCURS AT THE SAME TIME AS THE DEPOLARIZATION OF THE VENTRICLES III. BLOOD VESSELS ...
Until the groundbreaking musical Oklahoma! theater dancing was often little more than window dressing for a show. In fact, sometimes the story came to a virtual standstill while big production
"Thyroid Function Abnormalities during Amiodarone Therapy for Persistent Atrial Fibrillation". The American Journal of Medicine ... Its primary function is to increase the production of T3 and T4 by the thyroid gland. The most useful marker of thyroid gland ... Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the ... There are several hormones that can be measured in the blood to determine how the thyroid gland is functioning. These include ...
"Atrial endocrine function in humans with artificial hearts." ; Schwab T.R., Edwards B.S., DeVries W.C., Zimmerman R.S., Burnett ... February 1987 ; "Artificial Organs" ; PMID 3566584 "A clinical estimation model for noninvasive determination of atrial ...
Normal atrial function is essential for embryogenesis, as inactivation of the MYL7 gene was embryonic lethal at ED10.5-11.5. ... Huang C, Sheikh F, Hollander M, Cai C, Becker D, Chu PH, Evans S, Chen J (December 2003). "Embryonic atrial function is ... Atrial Light Chain-1 (ALC-1), also known as Essential Light Chain, Atrial is a protein that in humans is encoded by the MYL4 ... Shift in atrial myosin heavy chains and in ventricular myosin light chains" (PDF). European Heart Journal. 5 Suppl F: 85-93. ...
... has exactly the opposite function of the atrial natriuretic hormone secreted by the heart. Aldosterone is part of ... The amount of plasma renin secreted is an indirect function of the serum potassium as probably determined by sensors in the ... Aldosterone levels vary as an inverse function of sodium intake as sensed via osmotic pressure. The slope of the response of ... they share 11β-hydroxylation and 18-hydroxylation functions), but aldosterone synthase is also able to perform an 18-oxidation ...
The project was expanded by inviting all HUNT4 participants with atrial fibrillation to measure cardiac function and cardiac ...
... was Assessment of sino-atrial and atrio-ventricular nodal function in the conscious horse by intra-atrial electrostimulation. ... "Assessment of sino-atrial and atrio-ventricular nodal function in the conscious horse by intra-atrial electrostimulation". ...
... atrial function MeSH G09.330.582.075.100 - atrial function, left MeSH G09.330.582.075.200 - atrial function, right MeSH G09.330 ... ventricular function MeSH G09.330.582.962.800 - ventricular function, left MeSH G09.330.582.962.900 - ventricular function, ...
This pause is critical to heart function, as it allows the atrial cardiomyocytes to complete their contraction that pumps blood ... Atrial contraction, also referred to as the "atrial kick," contributes the remaining 20-30 percent of filling. Atrial systole ... Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; ... The function of the right heart, is to collect de-oxygenated blood, in the right atrium, from the body via the superior vena ...
The AV node connects the atrial and ventricular chambers. It functions to carry the electrical impulse from the atria to the ... Function[edit]. The common ostrich is an endotherm and maintains a body temperature of 38.1-39.7 °C (100.6-103.5 °F) in its ... Kidney function[edit]. Common ostrich kidneys are fairly large, and so are able to hold significant amounts of solutes. Hence, ... The wings also function as stabilizers to give better maneuverability when running. Tests have shown that the wings are ...
Prolonged atrial flutter with fast heart rates may lead to decompensation with loss of normal heart function (heart failure). ... Left atrial flutter is considered atypical and is common after incomplete left atrial ablation procedures. Atypical atrial ... Similar to the abnormal heart rhythm atrial fibrillation, atrial flutter also leads to poor contraction of the atrial chambers ... also known as common atrial flutter or typical atrial flutter, has an atrial rate of 240 to 340 beats/minute. However, this ...
... diastolic intervals consist of early rapid filling E-waves followed by diastasis and followed by atrial systole-generated A- ... Parallel to "diastolic function", the term "systolic function" is usually referenced in terms of the left ventricular ejection ... "diastolic function". Unlike "systolic function", which can be simply evaluated by LVEF, there are no established dimensionless ... To better understand diastolic function, it is crucial to realize that the left ventricle is a mechanical suction pump at, and ...
The main function of ANP is causing a reduction in expanded extracellular fluid (ECF) volume by increasing renal sodium ... Atrial natriuretic peptide (ANP) or atrial natriuretic factor (ANF) is a natriuretic peptide hormone secreted from the cardiac ... These cells contain volume receptors which respond to increased stretching of the atrial wall due to increased atrial blood ... ANP is secreted in response to: Stretching of the atrial wall, via Atrial volume receptors Increased Sympathetic stimulation of ...
Elevated right atrial pressure (>12mmHg), Moderate pulmonary hypertension, Normal systolic function, Poor diastolic function, ... Vasodilators are also typically ineffective because systolic function is usually preserved in cases of RCM. Heart failure ... Patients will demonstrate normal systolic function, diastolic dysfunction, and a restrictive filling pattern. 2-dimensional and ... except in the subgroup of restrictive cardiomyopathy with atrial fibrillation. ...
A stimulant, atrial natriuretic factor (ANF) increases cGMP production in the kidneys, which increases function of the ... The P region functions as a channel gate since it prevents ion permeation in the closed state. The pore may be hindered by ... Their function can be the result of a combination of the binding of cyclic nucleotides (cGMP and cAMP) and either a ... CNG channels have a very complex structure with various subunits and domains that play a critical role in their function. CNG ...
The discovery of right atrial mechanical function is a pivotal discovery in his medical research work. He is an editor for the ... He is best known for his discovery of the mechanical function of atrial chambers of the heart. With experimental evidence on ... atrial fibrillation and in improving the design and functioning of prosthetic hearts. Rai captained the Bangalore University ... The functioning of the Heart: Dr. Dinker Rai's Discovery- Bhavan's Journal VOL .5:9&10. February 1986 Newspaper Ten Deccan ...
... since these functioned as lightning rods, as was the case of the huge atrial cross of the Convent of San José de los Naturales ... Atrial cross in Tultitlán de Mariano Escobedo, Mexico. Atrial cross in the Cathedral of Mérida, Yucatán. The distances to ... Atrial cross (Spanish: Cruz atrial) is called, in the Mexican Colonial Conventual constructions, the sculptures of crosses ... The atrial crosses are usually placed on a pedestal or socle; they have only the face of Christ, a cartouche with the legend ...
Gu J.Y., Xu J.H., Yu H., Yang Y.Q. (2012). Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation.. ...
January 2007). "Germline gain-of-function mutations in SOS1 cause Noonan syndrome". Nature Genetics. 39 (1): 70-4. doi:10.1038/ ... This includes pulmonary valvular stenosis (50-60%), atrial septal defects (10-25%), ventricular septal defects (5-20%) and ... Accommodations for lessening handwriting demands will improve performance and save long-term hand function. Periodic follow up ... August 2007). "Germline gain-of-function mutations in RAF1 cause Noonan syndrome". Nature Genetics. 39 (8): 1013-7. doi:10.1038 ...
Less common findings include left ventricular hypertrophy, premature atrial and ventricular contractions, atrial fibrillation, ... Studies of thyroid function and immune parameters in patients with hyperthyroid Graves' disease in remission. Murakami M, ... January 2009). "Thyroid function abnormalities and cognitive impairment in elderly people: results of the Invecchiare in ... In a large population-based study of 2008, the odds of having poorer cognitive function were greater for subclinical ...
Both atria will be dilated (stretched or open) leading to future atrial arrhythmias or atrial fibrillation (Riaz). Pulmonary ... and functioning of left ventricle. The ECG can also be used to determine the rhythm of the heart to determine if there is an ... Mild left atrial enlargement: the test will help to determine if the left atrium is enlarged due to alternate blood flows Right ... If during the ECG, the P-wave (atrial depolarization) is tall, broad, or split waves in lead II and accompanied with a deep ...
... one for its antagonist function and the other for the agonist function. Azimilide has been studied for its anti-arrhythmic ... Prolongation of atrial or ventricular repolarization can provide an anti-arrhythmic benefit in patients with heart rhythm ... Both blockages result in an increase of the QT interval and a prolongation of atrial and ventricular refractory periods. ... Although each agent has its own properties and will have thus a different function. Azimilide dihydrochloride is a ...
... have been indicated in sporadic and familial cases of atrial isomerism. Disrupted mitochondria function has also been recently ... Right-atrial and left-atrial isomerism and associated pulmonary issues are treated in a series of steps based on the severity ... Left atrial appendage isomerism, also called left atrial isomerism, is a cardiac development defect in which the heart has 2 ... Right atrial appendage isomerism, also called right atrial isomerism, is a cardiac development defect in which the heart has ...
Diastole ends with atrial contraction, which ejects the final 30% of blood that is transferred from the left atrium to the left ... The function of the subvalvular apparatus is to keep the valves from prolapsing into the atria when they close. The subvalvular ... This amount of blood is known as the end diastolic volume (EDV), and the mitral valve closes at the end of atrial contraction ... Function of heart valves Artificial heart valve Pericardial heart valves Bjork-Shiley valve This article incorporates text in ...
Long-term therapy with pilsicainide is successful in treating chronic atrial fibrillation). It functions by blocking the fast ... It is especially effective in the treatment of atrial fibrillation. Atrial fibrillation is the most common type of arrhythmia. ... "Determination of refractory periods and conduction velocity during atrial fibrillation using atrial capture in dogs: direct ... Atrial fibrillation is characterized by rapid, disorganized electrical impulses in the atria resulting in depolarization of ...
... can have negative effects on heart function. Indeed, it has been associated with increased risk of atrial fibrillation, heart ... Right atrial and right ventricular leads as visualized under x-ray during a pacemaker implant procedure. The atrial lead is the ... Atrial septostomy. Balloon septostomy. creation of septal defect in heart Blalock-Hanlon procedure. shunt from heart chamber to ... as in atrial fibrillation. The equivalent atrial pacing mode is AAI or AAIR which is the mode of choice when atrioventricular ...
... which normally has no effect on platelet function). It can be used to treat people following ischemic strokes due to atrial ... In 1929, North Dakota veterinarian Lee M. Roderick demonstrated that the condition was due to a lack of functioning prothrombin ... Thus, common clinical indications for warfarin use are atrial fibrillation, the presence of artificial heart valves, deep ... Thyroid activity also appears to influence warfarin dosing requirements; hypothyroidism (decreased thyroid function) makes ...
It can be simplistically described as a failure of the pump function of the heart. It is characterized by a decreased ejection ... early-to-atrial left ventricular filling ratio), the E (early left ventricular filling) deceleration time, and the isovolumic ... After myocardial infarction, dead myocytes are replaced by scar tissue, deleteriously affecting the function of the myocardium ... May 2007). "Angiotensin II type 1 receptor blocker attenuates myocardial remodeling and preserves diastolic function in ...
The machine replaces both the heart's pumping action and the lungs' gas exchange function. Since the heart is stopped during ... and hospital mortality were similar Reduced incidence of postoperative atrial fibrillation compared to identical uncoated ... Duraflo II patients required less heparin to keep the target activated clotting time Effects on renal function and platelets ... damage organs and tissues and temporarily disturb organ function. All aspects of cardiopulmonary bypass, including manipulation ...
"Atrial Fibrillation and Cognitive Function: JACC Review Topic of the Week". Journal of the American College of Cardiology. 73 ( ... Valvular atrial fibrillation refers to atrial fibrillation attributable to moderate to severe mitral valve stenosis or atrial ... 193,300 with atrial flutter (2015)[10]. Atrial fibrillation (AF or A-fib) is an abnormal heart rhythm (arrhythmia) ... Left atrial appendage occlusion[edit]. There is tentative evidence that left atrial appendage occlusion therapy may reduce the ...
A balloon atrial septostomy is also done. This ensures that there is enough of a connection between the two atria of the heart ... as a result of the inability of the left heart to pump enough blood to sustain normal organ function. In fetal life, this is ... The atrial septum is removed, the aortic arch is reconstructed to remove any hypoplasia, and then the main pulmonary artery is ...
... atrial myxomas, and blue nevi. NAME refers to nevi, atrial myxoma, myxoid neurofibromas, and ephelides. Testicular cancer, ... Carney complex is most commonly caused by mutations in the PRKAR1A gene on chromosome 17 (17q23-q24) which may function as a ...
Molecular function. • calcium channel activity. • metal ion binding. • voltage-gated ion channel activity. • ion channel ... membrane depolarization during atrial cardiac muscle cell action potential. • cardiac muscle cell action potential involved in ... Structure and function[edit]. This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels ... Nomenclature and structure-function relationships of voltage-gated calcium channels". Pharmacological Reviews. 57 (4): 411-25. ...
Adrenoceptors: Structure, Function. and Pharmacology. Harwood Academic Publisher, Luxembourg. *^ Kokolus, Kathleen M.; Zhang, ... "Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic beta2-adrenoceptor ...
Right atrial and right ventricular leads as visualized under x-ray during a pacemaker implant procedure. The atrial lead is the ... Basic functionEdit. Modern pacemakers usually have multiple functions. The most basic form monitors the heart's native ... as in atrial fibrillation. The equivalent atrial pacing mode is AAI or AAIR which is the mode of choice when atrioventricular ... Advancements in functionEdit. Posteroanterior and lateral chest radiographs of a pacemaker with normally located leads in the ...
The gene was identified by positional cloning.[4] The EVC gene maps to the chromosome 4 short arm (4p16). The function of a ... Congenital heart defects (most commonly an atrial septal defect producing a common atrium, occurring in 60% of affected ... and may have served a useful function in defining this then little known condition for the medical profession, as well as the ...
Structure-function relationship in regulation of the energy transfere between mitochondria and ATPases in cardiac cell ( ... Compartmentation of energy metabolism in atrial myocardium of patients undergoing cardiac surgery (kaasautor). // Mol. Cell. ...
Adrenergic storm Alcohol Amphetamine Anaemia Antiarrhythmic agents Anxiety Atrial fibrillation Atrial flutter Atrial ... Unstable means that either important organ functions are affected or cardiac arrest is about to occur. In those that are ... vena cava Atrial fibrillation Atrial flutter AV nodal reentrant tachycardia Accessory pathway mediated tachycardia Atrial ... Atrial fibrillation is one of the most common cardiac arrhythmias. In general, it is an irregular, narrow complex rhythm. ...
Atrial fibrillation[edit]. Atrial fibrillation is one of the most common cardiac arrhythmias. In general, it is an irregular, ... Unstable means that either important organ functions are affected or cardiac arrest is about to occur.[4] ... Sinus tachycardia, which originates from the sino-atrial (SA) node, near the base of the superior vena cava ... Depending on the patient's health and other variables such as medications taken for rate control, atrial fibrillation may cause ...
"Complex" ablations include ablation for arrhythmias such as multifocal atrial tachycardia, atrial fibrillation, and ventricular ... Electrophysiologists are trained in the mechanism, function, and performance of the electrical activities of the heart. ... atrial flutter. These procedures are usually performed using intracardiac catheters (as are used during an electrophysiology ...
... the failure of the electronic functions of his Inspiration closed circuit rebreather (CCR) due to hydrodynamic forces from the ... Atrial septal defect. *Effects of drugs on fitness to dive. *Fitness to dive ...
The AV node connects the atrial and ventricular chambers. It functions to carry the electrical impulse from the atria to the ... Function. The common ostrich is an endotherm and maintains a body temperature of 38.1-39.7 °C (100.6-103.5 °F) in its extreme ... Kidney function. Common ostrich kidneys are fairly large, and so are able to hold significant amounts of solutes. Hence, common ... The wings also function as stabilizers to give better maneuverability when running. Tests have shown that the wings are ...
Atrial fibrillation is often due to serious underlying medical conditions, and should be evaluated by a physician. It is not ... Fibrillation occurs when the heart muscle begins a quivering motion due to a disunity in contractile cell function. ... Atrial fibrillation can also be treated through a procedure, e.g. pulmonary vein isolation. This is performed by a cardiologist ... Depending on the timing, this can produce a sustained abnormal rhythm, such as atrial flutter, a self-limiting burst of ...
Ring opening in the indole heterocyclic ring could generate new amine and keto functions. The new quinoline heterocycle would ... In people with atrial fibrillation, conduction defects, or heart block, quinine can cause heart arrhythmias, and should be ... and this nitrogen was then bonded to the acetaldehyde function to yield cinchonaminal. ...
Atrial septostomy. Balloon septostomy. creation of septal defect in heart Blalock-Hanlon procedure. shunt from heart chamber to ...
The liver also has many regulatory functions of the metabolism. An important function is the production and control of bile ... This causes heart muscle cells to secrete the hormone atrial natriuretic peptide (ANP) into the blood. This acts on the kidneys ... Kluge, Matthew J. (2015). Fever: Its Biology, Evolution, and Function. Princeton University Press. p. 57. ISBN 9781400869831.. ... Here blood sugar regulation is unable to function because the beta cells of the pancreatic islets are destroyed and cannot ...
... readily available laboratory tests of thyroid function. Many less severe cases of hypothyroidism went untreated.[citation ... and with higher rates of atrial fibrillation in elderly patients.[citation needed] ...
TIPS has been shown to improve kidney function in patients with hepatorenal syndrome.[8][37][38] Complications of TIPS for ... Effects on renal hemodynamics and atrial natriuretic factor". Gastroenterology. 101 (4): 1060-7. doi:10.1016/0016-5085(91)90734 ... Deteriorating liver function is believed to cause changes in the circulation that supplies the intestines, altering blood flow ... The vasopressin analogue ornipressin was found in a number of studies to be useful in improvement of kidney function in ...
... pulmonary infection or atrial fibrillation, inflammation, longer distances, longer duration of exercise, hard surfaces, ... with consequent loss of lung function. ...
Hemoglobin's function can also be lost by chemically oxidizing its iron atom to its ferric form. This form of inactive ... To improve lung function, doctors frequently place infants at risk of hypoxia inside incubators (also known as humidicribs) ... diseases interfering in lung function resulting in a ventilation-perfusion mismatch, such as a pulmonary embolus, or ... establishing a basis for how oxygen levels affect physiological function.[6][7] ...
The negative chronotropic effects of CCBs make them a commonly used class of agents in individuals with atrial fibrillation or ... Mohanakumar, Sheyanth; Telinius, Niklas; Kelly, Benjamin; Hjortdal, Vibeke (2019-08-20). "Reduced Lymphatic Function ... especially from atrial fibrillation), to prevent peripheral and cerebral vasospasm, and to reduce chest pain caused by angina ... channel poses a threat towards lymphatic removal of interstitial fluid essential for normal lymphatic system functioning.[17] ( ...
FunctionEdit. Major Aorta anatomy displaying Ascending Aorta, Brachiocephalic trunk, Left Common Carotid Artery, Left ... The difference between aortic and right atrial pressure accounts for blood flow in the circulation.[16] When the left ventricle ... The function of the aorta has been documented in the Talmud, where it is noted as one of three major vessels entering or ...
The second chamber functions as a "water seal", which acts as a one way valve allowing gas to escape, but not reenter the chest ... to the retained blood can lead to pleural and pericardial effusions and contribute to the triggering of postoperative atrial ... Alternatively, a large adhesive plaster that functions like a tape bridge may be used.[23] ...
Dynamic surface tensions, i.e. surface tension as a function of time, can be obtained by the maximum bubble pressure apparatus ... Atrial septal defect. *Effects of drugs on fitness to dive. *Fitness to dive ...
Diastole ends with atrial contraction, which ejects the final 30% of blood that is transferred from the left atrium to the left ... The function of the subvalvular apparatus is to keep the valves from prolapsing into the atria when they close. The subvalvular ... This amount of blood is known as the end diastolic volume (EDV), and the mitral valve closes at the end of atrial contraction ... During diastole, a normally-functioning mitral valve opens as a result of increased pressure from the left atrium as it fills ...
The other rare E.C.G. changes include deformity of QRS complexes, prolongation of PR interval, atrial premature beats, and ... Liver function tests. *Serological tests. Management[edit]. This section needs additional citations for verification. Please ... atrial tachycardia. In adults, fatal cases have been reported with a total dose of 0.6 G. or less. The incidence of toxic heart ...
Function[edit]. See also: Circulatory system. Blood vessels function to transport blood. In general, arteries and arterioles ... a b c Anatomy Physiology: The Unity of Form and Function, Saladin, McGraw Hill, 2012 ... Atrial. *Right marginal. *Posterior interventricular. *Left coronary: *Anterior interventricular. *Left circumflex (Left ...
Left atrial contraction (left atrial systole) (during left ventricular diastole) causes added blood to flow across the mitral ... Function[edit]. See also: Heart valves. During left ventricular diastole, after the pressure drops in the left ventricle due to ... pulmonary veins) → left atrium (atrial appendage) → mitral valve → left ventricle → aortic valve (aortic sinus) → (aorta and ... venae cavae, coronary sinus) → right atrium (atrial appendage, fossa ovalis, limbus of fossa ovalis, crista terminalis, valve ...
Intricate regulatory networks determine atrial function. Atrial fibrillation (AF) is the most common sustained arrhythmia, ... Atrial-specific pathways for control of intracellular signaling and myocyte function. Thomas J. Hund1,2,3 and Peter J. Mohler1, ... Atrial function is regulated by a variety of intracellular signaling networks that facilitate rapid communication and ... Cardiac atrial signaling "hubs" regulate local calcium signaling. (A) Schematic of the atrial myocyte TT and AT networks and ...
To obtain normal values for left atrial function noninvasively, volumes of the left atrium and ventricle were calculated in 52 ... Atrial Function*. Cardiac Volume. Echocardiography*. Female. Humans. Male. Middle Aged. Myocardial Contraction. Reference ... These values are similar to those reported in studies in which left atrial function was calculated from contrast angiography.. ... To obtain normal values for left atrial function noninvasively, volumes of the left atrium and ventricle were calculated in 52 ...
Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European ... OBJECTIVE: This study aimed to identify novel GATA5 mutations that underlie familial atrial fibrillation. METHODS: A total of ... GATA4 loss-of-function mutations in familial atrial fibrillation. Clin Chim Acta. 2011;412(19-20):1825-30, http://dx.doi.org/ ... Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339(10): ...
Objective: To examine the feasibility of using SI and SR to evaluate phasic atrial function in patients with mild hypertension ... measure regional myocardial deformation and may be a new technique to assess phasic atrial function. ... The following left atrial (LA) volumes were measured: (a) maximal LA volume or Volmax; (b) minimal LA volume or Volmin; (c) ... No significant difference was present in S-Sr, A-Sr or global atrial strain between the normal and HT cohorts. ...
... structure and function occur in patients with diastolic heart failure (DHF). The reasons for the transition from asymptomatic ... S), and atrial contraction (LAA) were measured. The ratio of wedge pressure to LAS strain was used as an index of LA stiffness ... Background-Abnormalities in left ventricular (LV) structure and function occur in patients with diastolic heart failure (DHF). ... with no significant difference between patients with DHF and diastolic dysfunction in LA systolic function indices, LV mass, LA ...
... causes tachycardia-induced atrial electrical remodeling, contributing to the progressive nature of the arrhythmia. Ventricular ... Atrial tissue from 1-week atrial-tachypaced dogs with ventricular rate control similarly showed upregulation of alpha SMA ... METHODS: Cultured canine atrial fibroblasts were treated with medium from rapidly-paced atrial cardiomyocytes, non-paced ... 18460289 - Atrial fibrillation and congestive heart failure.. 15851239 - Late recurrent arrhythmias after ablation of atrial ...
Our results indicate that Hrt2 acts in the ventricular myocardium to repress atrial gene expression, thereby functioning as a ... Repression of Atrial Gene Expression by Hrt2.. Based on the up-regulation of multiple atrial genes including Mlc1a, Mlc2a, Sln ... These findings reveal a ventricular myocardial cell-autonomous function for Hrt2 in the suppression of atrial cell identity and ... Repression of Atrial Genes by Hrt2.. To determine whether Hrt2 was sufficient to repress endogenous atrial gene expression, we ...
... Fang Yuan1#, Lan Zhao2#, Juan Wang3, Wei ... PITX2c Loss-of-Function Mutations Responsible for Congenital Atrial Septal Defects. Int J Med Sci 2013; 10(10):1422-1429. doi: ... These findings firstly link PITX2c loss-of-function mutations to atrial septal defects in humans, which provide novel insight ... Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is ...
M XiaQ JinS BendahhouY HeMM LarroqueY ChenQ ZhouY YangY LiuB LiuA Kir2.1 gain-of-function mutation underlies familial atrial ... Li, J., Liu, W., Yang, Z., Yang, Y.Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation. ... Li, J., Liu, W., Yang, Z., Yang, Y.Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation. ... Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation. *Authors: *Jian Li ...
Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children. Peter L. Stavinoha, ... Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children ... Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children ... Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children ...
Heart Rate Increase Pindolol Cardiac Pacemaker Pump Function Pacemaker Activity These keywords were added by machine and not by ...
Keywords: thyroid function, epicardial fat, atrial fibrillation, causal mediation analysis ... The underlying mechanism of the association between thyroid function and atrial fibrillation (AF) is poorly understood, but ... We report no mediating role of EAT in the association of thyroid function with AF, but found evidence for a suggested ... We found no evidence of a mediating role of EAT in the association of thyroid function with AF (mediated interaction 1.6%, pure ...
... Rundqvist, Louise Jönköping ... 50 mL/m(2) (P amp;lt; 0.001), left atrial volume 27 vs. 19 mL/m(2) (P amp;lt; 0.001), and right ventricular (RV) and right ... The aims of the study were to explore the effects of long-term endurance exercise on atrial and ventricular size and function ... Further, we found improved systolic function in the active group compared with controls: left ventricular ejection fraction 61 ...
Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement ( ... left atrial (LA) function was assessed at baseline and after 12 months treatment using 2-D echocardiography and interpreted ... Evaluate the effects of dronedarone versus placebo on left atrial function;. *Evaluate the effects of dronedarone versus ... Changes From Baseline in Left Atrial Function [ Time Frame: baseline (before randomization) and post-baseline (after 3-12 ...
... and Function. Petr Kuchynka,1,2 Jana Podzimkova,1 Martin Masek,3 Lukas Lambert,3 Vladimir Cerny,3 Barbara Danek,1 and Tomas ... atrial fibrillation require the need for detailed knowledge of left atrial and pulmonary venous morphology as well of atrial ... This review article discusses the role of cardiac magnetic resonance and computed tomography in assessment of left atrial size ... The Role of Magnetic Resonance Imaging and Cardiac Computed Tomography in the Assessment of Left Atrial Anatomy, Size, ...
"Right atrial MR imaging studies of cadaveric atrial casts and comparison with right and left atrial volumes and function in ... "Left atrial function and scar after catheter ablation of atrial fibrillation," Heart Rhythm, vol. 5, no. 5, pp. 656-662, 2008. ... "Left atrial transport function in myocardial infarction. Importance of its booster pump function," The American Journal of ... "Assessment of left atrial volume and function in patients with permanent atrial fibrillation: comparison of cardiac magnetic ...
Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis. Divya ... Background: Left atrial (LA) function by volume and strain analysis in children has been little studied. LA dysfunction related ... Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis ... Abstract 13554: Left Atrial Function in Children by Volume and Strain Analysis: Impact of Congenital Aortic Stenosis ...
Recurrent pleural effusions, resistant atrial arrhythmias, and abnormal liver function tests: general medicine or cardiology? ... Recurrent pleural effusions, resistant atrial arrhythmias, and abnormal liver function tests: general medicine or cardiology? ... While awaiting an open pleural biopsy the patient was admitted with a further pleural effusion, jaundice, resistant atrial ...
2007) Improvement of atrial function and atrial reverse remodeling after cardiac resynchronization therapy for heart failure. J ... 1) several baseline data concerning atrial function are presented (left atrial volume index and mitral regurgitation severity ... Atrial Function in Patients Undergoing CRT Message Subject (Your Name) has forwarded a page to you from JACC: Cardiovascular ... In recent years, there has been growing interest in the potential impact of CRT on atrial function, but the state of knowledge ...
... bosentan therapy improves ventricular and atrial functions resulting in enhancement of physical exercise and reduction in the ... Effect of bosentan therapy on ventricular and atrial function in adults with Eisenmenger syndrome. A prospective, multicenter ... Conclusions: In adult patients with Eisenmenger syndrome, bosentan therapy improves ventricular and atrial functions resulting ... ventricular and atrial function, and pulmonary hemodynamics. Methods: Forty adult patients before and after 24 weeks bosentan ...
Patients with CHF commonly have atrial fibrillation or flutter (AF), which is frequently associated with, may be a marker for, ... of Atrial Fibrillation or Flutter Whether Systolic Function Is Preserved or Depressed" written by Jacob I. Haft, Louis E. ... Letter by Haft Regarding Article, "High Prevalence of Atrial Fibrillation Among Patients With Ischemic Stroke". Stroke, 2015. ... Letter by Haft Regarding Article,"High Prevalence of Atrial Fibrillation Among Patients With Ischemic Stroke" ...
Patients with CHF commonly have atrial fibrillation or flutter (AF), which is frequently associated with, may be a marker for, ... of Atrial Fibrillation or Flutter Whether Systolic Function Is Preserved or Depressed. World Journal of Cardiovascular Diseases ... of Atrial Fibrillation or Flutter Whether Systolic Function Is Preserved or Depressed ... Stroke Risk in Atrial Fibrillation Working Group (2008) Comparison of 12 Risk Stratification Schemes to Predict Stroke in ...
2012) The impact of atrial fibrillation ablation left atrial function: association with baseline left atrial function. Pacing ... left atrial. LAKE. left atrial kinetic energy. LAV. left atrial volume. LAVi. left atrial volume indexed to body surface area. ... 1999) Left atrial relaxation and left ventricular systolic function determine left atrial reservoir function. Circulation 100: ... atrial function is abnormal in HCM. Increases in booster pump function and impaired reservoir and conduit functions have been ...
Effect of low dose infusion of atrial natriuretic peptide on renal function in man. L. R. Solomon, J. C. Atherton, H. Bobinski ... Effect of low dose infusion of atrial natriuretic peptide on renal function in man ... Effect of low dose infusion of atrial natriuretic peptide on renal function in man ... Effect of low dose infusion of atrial natriuretic peptide on renal function in man ...
Impairment of Pulmonary Function is an Independent Risk Factor for Atrial Fibrillation: The Takahata Study Yoko Shibata1✉, ... Keywords: atrial fibrillation, pulmonary function, general population This is an open access article distributed under the ... Impairment of Pulmonary Function is an Independent Risk Factor for Atrial Fibrillation: The Takahata Study. Int J Med Sci 2011 ... The relationship between the prevalence of AF and pulmonary function is unclear. The aim of this study was to evaluate this ...
... function in success of electrial cardioversion (ECV) in patients with nonvalvular atrial fibrillation (NVAF), and observe the ... of LAA and left atrial spontaneous echo contrast (SEC) of left atrial appendage before ECV and after ECV 24 hours, 3 days and 1 ... thrombogenic milieu Patients with atrial fibrillation should be given full anticoagulation to prevent thrombogenesis in left ... course of the recovery of LAA systaltic function Methods To test blood flow wave patterns, peak emptying velocity (PEV) ...
Aged, Atrial Fibrillation/metabolism/physiopathology/*surgery/ultrasonography, Atrial Function, Atrial Natriuretic Factor/blood ... Atrial function after epicardial microwave ablation in patients with atrial fibrillation. Ahlsson, Anders Örebro University, ... Tissue velocity echocardiography on patients in sinus rhythm showed preserved atrial wall velocities, atrial strain, and atrial ... To study epicardial microwave ablation of concomitant atrial fibrillation and its effects on heart rhythm and atrial function ...
Left atrial myocardial function in either physiological or pathological left ventricular hypertrophy: a two-dimensional speckle ... Left atrial myocardial function in either physiological or pathological left ventricular hypertrophy: a two-dimensional speckle ...
... echocardiographic measures of cardiac structure and function are significantly associated with an increased risk of AF. ... Echocardiographic Measures of Cardiac Structure and Function Are Associated With Risk of Atrial Fibrillation in Blacks: The ... Background: Several studies have examined the link between atrial fibrillation (AF) and various echocardiographic measures of ... Conclusions: In a community-based population of blacks, echocardiographic measures of cardiac structure and function are ...
1998) Assessment of left atrial appendage function after cardioversion of atrial fibrillation: relation to left atrial ... 1997) Left atrial chamber and appendage function after internal atrial defibrillation: a prospective and serial transesophageal ... 1994) Left atrial appendage function and thrombus formation in atrial fibrillation-flutter: a transesophageal echocardiographic ... 1993) Impact of electrical cardioversion for atrial fibrillation on left atrial appendage function and spontaneous echo ...
  • Two novel heterozygous GATA5 mutations (p.Y138F and p.C210G) were identified in two of the 110 unrelated atrial fibrillation families. (scielo.br)
  • Furthermore, advances in catheter ablation procedures used for the treatment of drug-refractory atrial fibrillation require the need for detailed knowledge of left atrial and pulmonary venous morphology as well of atrial wall characteristics. (hindawi.com)
  • Special interest is paid to the utility of these rapidly involving noninvasive imaging methods before and after atrial fibrillation ablation. (hindawi.com)
  • OBJECTIVES: To study epicardial microwave ablation of concomitant atrial fibrillation and its effects on heart rhythm and atrial function during follow-up. (diva-portal.org)
  • and atrial function after concomitant surgical ablation for AF. (diva-portal.org)
  • This guidance provides FDA's recommendations on clinical trial designs for surgical ablation devices intended for the treatment of atrial fibrillation (AF). (fda.gov)
  • Atrioventricular conduction properties in patients with prolonged pauses undergoing ablation of longstanding persistent atrial fibrillation: do pauses during atrial fibrillation matter? (meta.org)
  • Radiofrequency catheter ablation is not superior to antiarrhythmic drug therapy as first-line treatment in patients with symptomatic paroxysmal atrial fibrillation-but it may be a reasonable alternative. (medpagetoday.com)
  • Little is known on atrial mechanical function and the time course of atrial recovery following radiofrequency ablation of AFI. (elsevier.com)
  • Transthoracic echocardiography (TTE) was performed immediately after ablation, then repeated after 1 day, 1 week, and 6 weeks to measure peak transmitral velocities and percent atrial contribution to ventricular filling. (elsevier.com)
  • Left atrial appendage emptying velocities decreased significantly following AFI termination (44 ± 23 cm/s before ablation vs 25 ± 14 cm/s after ablation, p = 0.01). (elsevier.com)
  • Four patients had complete atrial standstill after ablation, and 1 patient developed a new left atrial appendage thrombus. (elsevier.com)
  • Thus, atrial stunning occurs after catheter ablation of AFI and may lead to rapid formation of thrombus in the left atrial appendage. (elsevier.com)
  • By contrast, novel therapeutic options such as radiofrequency catheter ablation techniques and transcatheter closure of the left atrial appendage (LAA) demand advanced imaging to maximize patient safety and procedural outcomes. (onlinejacc.org)
  • We assessed the effects of catheter ablation of PVCs on parameters of LV diastolic function and LA remodeling. (elsevier.com)
  • We also compared the changes in the left atrial volumes and left atrial volume index (LAVI) after PVC ablation. (elsevier.com)
  • Conclusion: Catheter ablation of PVCs improved LV diastolic function and resulted in left atrial reverse remodeling. (elsevier.com)
  • Catheter ablation for atrial fibrillatio. (cumhuriyet.edu.tr)
  • It is still unknown whether left ventricular ejection fraction (LVEF) might affect the magnitude of improvement after atrial fibrillation (AF) ablation on cardiac function in persistent or longstanding persistent AF (CAF) patients. (cumhuriyet.edu.tr)
  • Success rate of one-stop procedure for atrial fibrillation ablation and its impact on cardiac function: a propensity-matched study]. (bvsalud.org)
  • To investigate the effect of the combination of atrial fibrillation (AF) ablation and left atrial appendage closure (LAAC) on cardiac function and the success rate of AF ablation. (bvsalud.org)
  • but the improvement of cardiac function was more obvious in the control patients undergoing AF ablation alone (P (bvsalud.org)
  • The one-stop procedure can improve cardiac function of the patients , but AF ablation alone can achieve better improvement of cardiac function. (bvsalud.org)
  • To examine the incidence of TICM in patients undergoing ablation for persistent atrial flutter, and to examine predictors for the development of TICM. (nih.gov)
  • Here, we have identified a membrane structure and Ca 2+ -signaling complex that may enhance the speed of atrial contraction independently of phospholamban regulation. (jci.org)
  • In this issue of the JCI , Brandenburg and colleagues describe the identification and characterization of "super-hub" signaling nodes located on atrial axial tubules that regulate atrial contraction. (jci.org)
  • Together, the results of this study provide important insight into the regulation of atrial contraction and describe potential therapeutic targets to be explored in future studies. (jci.org)
  • S ), and atrial contraction (LA A ) were measured. (ovid.com)
  • Additional value of analyzing left atrial size, left atrial ejection fraction and the difference in duration of pulmonary venous and mitral flow velocity at atrial contraction," Journal of the American College of Cardiology , vol. 22, no. 7, pp. 1972-1982, 1993. (hindawi.com)
  • All patients in sinus rhythm had preserved left and right atrial-filling waves through atrioventricular valves during atrial contraction. (diva-portal.org)
  • Strong correlation between ALDAF-V, atrioventricular interval, and electrical PR interval suggests that ALDAF coincides with atrial contraction. (elsevier.com)
  • Conclusion: ALDAF results from atrial contraction. (elsevier.com)
  • This was mainly achieved by increasing atrial contraction (A-wave), maintaining cardiac output by increasing heart rate. (bgu.ac.il)
  • Left atrial minimum volume (LAVmin), left atrial pre-atrial contraction volume (LAVp) and left atrial maximum volume (LAVmax) were measured by Simpson's rule, whereas left atrial active ejection fraction (LAAEF) and left atrial passive ejection fraction (LAPEF) were obtained from calculation. (biomedcentral.com)
  • Booster pump phase: contributing to RV filling in late diastole by atrial contraction. (elsevier.pt)
  • The reservoir and conduit phases are often termed passive phases, whereas the atrial contraction phase is considered the active phase. (elsevier.pt)
  • Maximum, minimum and pre-atrial contraction (pre-A) LA volumes (ml/m2) were 21.2 ± 5.5, 7.8 ± 2.5, and 11.0 ± 3.1, respectively. (bvsalud.org)
  • LA SR curves were similarly obtained to determine the peak positive strain rate (SRs) during left ventricle systole, the first negative peak strain rate (SRe) during early diastole and the second negative peak strain rate (SRa) during atrial contraction. (sonopath.com)
  • Normal left atrial function determined by 2-dimensional echocardiography. (biomedsearch.com)
  • To obtain normal values for left atrial function noninvasively, volumes of the left atrium and ventricle were calculated in 52 volunteers by 2-dimensional echocardiography. (biomedsearch.com)
  • Left Atrial Volume index (LAVi) was assessed at baseline and after 12 months treatment using 2-D echocardiography and interpreted blindly via a central Echocardiography Core Lab. (clinicaltrials.gov)
  • left atrial (LA) function was assessed at baseline and after 12 months treatment using 2-D echocardiography and interpreted blindly via a central Echocardiography Core Lab. (clinicaltrials.gov)
  • Maximal left atrial diameter in the anteroposterior dimension was assessed at baseline and after 12 months treatment using 2-D echocardiography and interpreted blindly via a central Echocardiography Core Lab. (clinicaltrials.gov)
  • Minimum vs. maximum left atrial volume for prediction of first atrial fibrillation or flutter in an elderly cohort: a prospective study," European Journal of Echocardiography , vol. 10, no. 2, pp. 282-286, 2008. (hindawi.com)
  • Assessment of left atrial volume and function in patients with permanent atrial fibrillation: comparison of cardiac magnetic resonance imaging, 320-slice multi-detector computed tomography, and transthoracic echocardiography," European Heart Journal Cardiovascular Imaging , vol. 15, no. 5, pp. 532-540, 2014. (hindawi.com)
  • Atrial size and function can be assessed with echocardiography, cardiac computed tomography (CCT), and cardiac magnetic resonance (CMR). (onlinejacc.org)
  • Tissue velocity echocardiography on patients in sinus rhythm showed preserved atrial wall velocities, atrial strain, and atrial strain rate. (diva-portal.org)
  • We evaluated the potential utility of two-dimensional (2D) Strain-Strain rate (S-SR) and 3D echocardiography to quantitatively assess RV, LV and atrial function in ARVC patients (pts), with apparently normal LV. (ovid.com)
  • Our aim was to evaluate volumetric and functional atrial parameters, using real time three-dimensional echocardiography (RT3DE) in women in early and late third trimester of pregnancy. (bgu.ac.il)
  • In patients with a documented sinus rhythm (SR) at follow-up, the presence of atrial transport function was assessed with transthoracic echocardiography. (thefreedictionary.com)
  • Left atrial functional indices and measurements obtained from 2-dimensional echocardiography of healthy dogs and dogs with myxomatous mitral valve disease. (mendeley.com)
  • And two-dimensional speckle tracking echocardiography (2D-STE) has been reported very useful in evaluating left atrial (LA) function, as well as left ventricular (LV) function. (biomedcentral.com)
  • 90 g/L) and group C (Hb60 ~ 90 g/L). Another 30 healthy people were also selected as control group A. Conventional echocardiography parameters, such as left atrial diameter (LAD), peak E and A of mitralis (E, A), E/A, end-diastolic thickness of ventricular septum (IVST d), end-diastolic thickness of LV posterior wall (PWTd) and left ventricular end-diastolic dimension (LVDd) were obtained from these three groups. (biomedcentral.com)
  • Right atrial function with speckle tracking echocardiography: Do we really need it? (elsevier.pt)
  • 5 Subsequently, analysis of right atrial (RA) mechanics using two-dimensional (2D) speckle tracking echocardiography (STE) also proved feasible, 6-12 and normal reference values have been published. (elsevier.pt)
  • Percutaneous closure of the left atrial appendage: The value of real time 3D transesophageal echocardiography and the intraoperative change in the size of the left atrial appendage. (bioportfolio.com)
  • The aim of this study was to investigate the value of real time three-dimensional transesophageal echocardiography (RT3DTEE) in percutaneous closure of the left atrial appendage (LAAC). (bioportfolio.com)
  • Speckle tracking echocardiography (STE) for two-dimensional (2D) strain analysis is a new tool to assess myocardial function. (revportcardiol.org)
  • Background: Left atrial (LA) strain (ε) and ε rate (SR) analysis by 2-dimensional speckle tracking echocardiography is a novel method for functional assessment of the LA. Objective: The purpose of this study was to determine the impact of left atrial appendage (LAA) exclusion by Lariat epicardial ligation on mechanical function of the LA by performing ε and SR analysis before and after the procedure. (elsevier.com)
  • Predictive role of left atrial and ventricular mechanical function in postoperative atrial fibrillation: a two-dimensional speckle-tracking echocardiography study. (acibadem.edu.tr)
  • Left atrial (LA) function (consisting of 3 phases: reservoir, conduit and booster pump) can be evaluated by speckle tracking echocardiography (STE) which measures myofiber deformation during these phases. (sonopath.com)
  • Objectives: To investigate whether there is a relation between mitral annular velocities obtained by Doppler tissue imaging (DTI) and LAA function determined by transoesophageal echocardiography (TEE) and to determine if the annular velocities can predict the presence of the inactive LAA in MS. Methods: Sixty MS patients were evaluated by transthoracic echocardiography and all patients underwent transesophageal echocardiography. (who.int)
  • Right atrial peak strain derived from 2D-STE has been proved to be a reliable tool to study RA performance. (elsevier.pt)
  • Release of atriopeptin in the rat by vasoconstrictors or water immersion correlates with changes in right atrial pressure. (springer.com)
  • It can be also estimated using various imaging techniques or other pressure readings such as PULMONARY CAPILLARY WEDGE PRESSURE (an estimate of left atrial pressure) and CENTRAL VENOUS PRESSURE (an estimate of right atrial pressure). (bioportfolio.com)
  • Correlations between right atrial longitudinal strain and other echocardiographic parameters in patients with atrial septal defect. (revportcardiol.org)
  • The aim of this study was to assess right atrial (RA) function using STE in patients with an atrial septal defect (ASD) before and one month after percutaneous closure. (revportcardiol.org)
  • Patients with CHF commonly have atrial fibrillation or flutter (AF), which is frequently associated with, may be a marker for, and may be the mechanism of, ischemic strokes. (scirp.org)
  • Efficacy of Dofetilide in the Treatment of Atrial Fibrillation-Flutter in Patients With Reduced Left Ventricular Function. (acc.org)
  • Atrial stunning, as assessed by left atrial appendage emptying and increased spontaneous echo contrast, is known to occur following direct- current cardioversion of atrial fibrillation (AF) and atrial flutter (AFI). (elsevier.com)
  • Frequency and predictors of tachycardia-induced cardiomyopathy in patients with persistent atrial flutter. (nih.gov)
  • In multivariate analysis, average ventricular rate during atrial flutter was the only independent predictor of reversibility of cardiomyopathy (P=0.013). (nih.gov)
  • Sixteen of 28 (57%) cardiomyopathy patients with persistent atrial flutter had significantly improved LV function postablation. (nih.gov)
  • Atrial fibrillation (AF) is a cardiac arrhythmia that arises from electrical and contractile dysfunction in the atria. (jci.org)
  • The findings expand the spectrum of GATA5 mutations linked to AF and provide novel insights into the molecular mechanism involved in the pathogenesis of atrial fibrillation, suggesting potential implications for the early prophylaxis and personalized treatment of this common arrhythmia. (scielo.br)
  • Atrial fibrillation (AF) is the most common form of cardiac arrhythmia seen in clinical practice, accounting for approximately one-third of hospitalizations for cardiac rhythm disturbances. (scielo.br)
  • Atrial fibrillation (AF) is the most commonly sustained cardiac arrhythmia, and confers a substantially increased risk of morbidity and mortality. (spandidos-publications.com)
  • Atrial fibrillation (AF) is the most common type of sustained cardiac arrhythmia, accounting for approximately 1/3 of hospitalizations for heart rhythm disorders ( 1 ). (spandidos-publications.com)
  • Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice. (diva-portal.org)
  • Influence of heart rate and atrial transport on left ventricular volume and function: relation to hemodynamic changes produced by supraventricular arrhythmia. (ucl.ac.uk)
  • Atrial fibrillation is a complex arrhythmia and its precise mechanisms remain unclear. (fda.gov)
  • Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. (meta.org)
  • Atrial Fibrillation (AF) is the most common type of arrhythmia. (frontiersin.org)
  • Atrial fibrillation is the most common type of heart arrhythmia, which means the heart beats too slowly, too fast, or in an irregular pattern. (intermountainhealthcare.org)
  • Left atrial (LA) function helps to preserve cardiac output and to control pulmonary capillary wedge pressure in the setting of left ventricular (LV) impairment, but little is known about the contribution of the LA function to ventricular arrhythmia. (edu.au)
  • The perioperative complications , thromboembolic events, recurrence of atrial arrhythmia and cardiac function were compared between the groups. (bvsalud.org)
  • Atrial fibrillation is a common cardiac arrhythmia and an important risk factor for ischaemic stroke and heart failure. (bmj.com)
  • As a result, two novel heterozygous PITX2c mutations, p.H98Q and p.M119T, were identified in 2 unrelated patients with atrial septal defects, respectively. (medsci.org)
  • These findings firstly link PITX2c loss-of-function mutations to atrial septal defects in humans, which provide novel insight into the molecular mechanism responsible for CHD, suggesting potential implications for the early prophylaxis and allele-specific treatment of CHD. (medsci.org)
  • Methods and Results- We evaluated neurocognitive function in subjects aged 3 to 17 years both before and after surgical repair of an atrial septal defect (ASD). (ahajournals.org)
  • Recently, Visconti et al 15 addressed some of these problems by performing a retrospective study in which a group of children who underwent closure of an atrial septal defect (ASD) by surgery were compared with another group of children who underwent ASD closure by a catheter-delivered device. (ahajournals.org)
  • We therefore performed a prospective observational study in which we evaluated cognitive function in subjects both before and after surgical repair of an atrial septal defect. (ahajournals.org)
  • In addition, the development of new interventional transcatheter procedures for AF, mitral valve repair, atrial septal defect closure, and LAA occlusion may result in intentional or unintentional instrumentation of the LAA. (onlinejacc.org)
  • Atrial septal defect (ASD) is one of the most common congenital cardiac anomalies presenting in adulthood. (elsevier.pt)
  • The three major types of atrial septal defect (ostium secundum, ostium primum and sinus venosus) account for 10% of all congenital heart defects and as much as 20-40% of congenital heart disease presenting in adulthood. (elsevier.pt)
  • Clinical characteristics and echocardiographic measurements in patients with atrial septal defect. (revportcardiol.org)
  • Effects of atrial septal defect closure on echocardiographic parameters. (revportcardiol.org)
  • GATA4 loss-of-function mutations in familial atrial fibrillation. (cdc.gov)
  • Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation. (cdc.gov)
  • The study, conducted with the National Heart, Lung, and Blood Institute (NHLBI) Trans-Omics for Precision Medicine (TOPMed) Consortium , was published in JAMA and represents the first time that researchers have been able to link loss-of-function mutations in a single gene to early-onset Afib. (broadinstitute.org)
  • Loss-of-function mutations in it account for many cardiomyopathies. (broadinstitute.org)
  • The global peak atrial longitudinal strain and strain rate of systolic LV (GLSs, GLSRs) as well as early and late diastolic LV strain rate (GLSRe, GLSRa) curves of LA were acquired in each LA segment from basal segment to top segment of LA by 2D-STE. (biomedcentral.com)
  • 16 Peak atrial strain (the peak of the positive deflection occurring during the reservoir phase, when the right ventricle contracts and the right atrium fills against a closed tricuspid valve) is perhaps the most used parameter of RA function. (elsevier.pt)
  • RA volume 18 - for the same amount of blood received, dilated atria have lower peak atrial strain than non-dilated atria ( Figure 3 ). (elsevier.pt)
  • In accordance with the above, since a chronic significant left-to-right shunt through an ASD leads to a varying degree of RA dilatation due to volume overload, peak atrial strain should be decreased in ASD patients, who have dilated atria. (elsevier.pt)
  • Further, we found improved systolic function in the active group compared with controls: left ventricular ejection fraction 61 vs. 59% (P = 0.036), tricuspid annular plane systolic excursion 12 vs. 10 mm/m(2) (P = 0.008), and RV early peak systolic velocity s 11 vs. 10 cm/s (P = 0.031). (diva-portal.org)
  • Atrial kick (AK) accounts for 10-15% of the ejection fraction. (rero.ch)
  • In 10 patients count-derived left ventricular ejection fraction, end-diastolic volume and stroke volume were measured during sinus rhythm and during atrial pacing at 120, 140 and 160 beats/min. (ucl.ac.uk)
  • Left ventricular ejection fraction did not change significantly with atrial pacing (from 0.65 +/- 0.02 [mean +/- standard error of the mean] at a baseline sinus rate of 91 +/- 3 beats/min to 0.62 +/- 0.03 at 160 beats/min) despite a progressive decrease in end-diastolic volume. (ucl.ac.uk)
  • The data indicate that the hemodynamic consequences of supraventricular tachyarrhythmias in patients with normal ventricular function are due primarily to decreases in ventricular volume as heart rate is increased and atrial contribution is lost rather than to any changes in left ventricular ejection fraction. (ucl.ac.uk)
  • While 'ejection fraction' is the phrase used for reduction of ventricular cavity volume, 'emptying function' is more appropriate for reductions of atrial volume as the atria lack inflow valves and empty passively as well as actively. (biomedcentral.com)
  • We correlated post AFCA scar with cardiac volumes and function including LA volume, LV ejection fraction (LVEF), and LV cardiac output (LVCO). (biomedcentral.com)
  • Left atrial dysfunction relates to symptom onset in patients with heart failure and preserved left ventricular ejection fraction. (nih.gov)
  • These findings reveal a ventricular myocardial cell-autonomous function for Hrt2 in the suppression of atrial cell identity and the maintenance of postnatal cardiac function. (pnas.org)
  • Left atrial volume: a powerful predictor of survival after acute myocardial infarction," Circulation , vol. 107, no. 17, pp. 2207-2212, 2003. (hindawi.com)
  • A consecutive group of patients with chronic hypertension but without significant valvular disease or prior MI underwent clinically-indicated CMR for assessment of left ventricular (LV) function, myocardial ischemia, or viability. (biomedcentral.com)
  • Patients were referred either for a) evaluation for myocardial ischemia with stress CMR or b) assessment of regional and global left ventricular function and myocardial mass. (biomedcentral.com)
  • OBJECTIVES: To assess the comparative effectiveness of left atrial (LA) functional parameters (left atrial emptying fraction (LAEF), left atrial expansion index (LAi) and minimal left atrial volume index (MinLAVI)) with that of LA volume index (LAVI) in predicting heart failure (HF) and death following ST-elevated myocardial infarction (STEMI). (regionh.dk)
  • A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats. (springer.com)
  • Echocardiographic LA volumes (LAVs), mitral valve early (MV-E) and late (MV-A) peak flow velocities, and mitral atrioventricular plane tissue-Doppler early (TD-e ') and late (TD-a ') peak velocities were obtained in 320 patients with acute myocardial infarction (AMI) free from atrial fibrillation and more than moderate valvular disease. (kb.se)
  • Subjects were excluded if they did not speak English or if any of the following was present: associated congenital heart defects that required cardiac surgery (except for partial anomalous pulmonary venous return associated with a sinus venosus ASD or a very small patent ductus arteriosus), congestive heart failure or pulmonary hypertension, anomalies that affect cognitive function, or chronic disease likely affecting development, such as bronchopulmonary dysplasia. (ahajournals.org)
  • In adult patients with Eisenmenger syndrome, we aimed to evaluate the midterm effect of bosentan on physical exercise, ventricular and atrial function, and pulmonary hemodynamics. (nih.gov)
  • In adult patients with Eisenmenger syndrome, bosentan therapy improves ventricular and atrial functions resulting in enhancement of physical exercise and reduction in the NT-proBNP level, while the pulmonary vascular resistance does not change substantially. (nih.gov)
  • The principal role of the left atrium is to modulate left ventricular (LV) filling and cardiovascular performance by functioning as a reservoir for pulmonary venous return during ventricular systole, a conduit for pulmonary venous return during early ventricular diastole, and a booster pump that augments ventricular filling during late ventricular diastole. (onlinejacc.org)
  • Chronic pulmonary disorders, such as chronic obstructive pulmonary disease (COPD) and fibrosing lung diseases, and atrial fibrillation (AF), are prevalent in elderly people. (medsci.org)
  • The impact of cardiac co-morbidities in the elderly, where pulmonary function is impaired, cannot be ignored as they influence mortality. (medsci.org)
  • The relationship between the prevalence of AF and pulmonary function is unclear. (medsci.org)
  • Impaired pulmonary function is an independent risk factor for AF in the Japanese general population. (medsci.org)
  • These LA functions mechanically facilitate the transition between flow through the pulmonary venous circulation and the intermittent filling of the left ventricle [ 6 , 7 ]. (kjim.org)
  • Atrial natriuretic peptide concentrations in plasma of children with congenital heart and pulmonary diseases. (springer.com)
  • In conclusion, a reduced atrial function was associated with smaller LA reservoir volume, larger LA transit volume, lower TD-a ', a non-linear decrease in MV-A and a non-linear increase in E/A. Our findings are likely a reflection of the adaptation to sustain LV filling volume and counteracting a rise in pulmonary venous pressure in face of an enhanced LV end-diastolic pressure. (kb.se)
  • Then, to calculate end-systolic and end-diastolic atrial and ventricular volumes, a modified Simpson's rule formula was used. (biomedsearch.com)
  • End-systolic left atrial volume (mean +/- standard deviation) was 37 +/- 11.7 ml or 21 +/- 6.6 ml/m2. (biomedsearch.com)
  • For example, although reservoir function is governed by atrial compliance during ventricular systole (and, to a lesser extent, by atrial contractility and relaxation), it is influenced by descent of the LV base during systole and by LV end-systolic volume (1) . (onlinejacc.org)
  • Finally, atrial booster pump function reflects the magnitude and timing of atrial contractility but is dependent on the degree of venous return (atrial pre-load), LV end-diastolic pressures (atrial afterload), and LV systolic reserve. (onlinejacc.org)
  • We measured 2D longitudinal systolic ventricular and atrial S-SR in apical 4 and 2-chambers views, at level of LV segments (4 basal,4 mid,4 apical), RV segments (1 basal,1 mid,1apical) and atrial walls and circonferential and radial peak systolic LV 2D S-SR in short axis views. (ovid.com)
  • The electromechanical delay parameters were measured from the onset of the P wave on the surface electrocardiogram to the onset of the atrial systolic wave on tissue Doppler imaging from septum, lateral, and right ventricular annuli. (kjim.org)
  • Methods: We studied pregnant women in early third trimester (III-E = gestational age 26-33 weeks), in late third trimester (III-L = gestational age 34-40 weeks), and control nonpregnant women (C). Two-dimensional (2D-Echo) and RT3DE were used to study 3D left atrial (LA) systolic and diastolic stroke volumes and index (LASVI, LAEDVI), emptying fraction, left ventricular and LA cavities. (bgu.ac.il)
  • IMSEAR at SEARO: Role of Mitral Annular Systolic Velocity in The Evaluation of Left Atrial Appendage Function in Mitral Stenosis. (who.int)
  • Majumder A A S, Tanveer M S, Reza A Q M, Chowdhury A W, Shahabuddin M. Role of Mitral Annular Systolic Velocity in The Evaluation of Left Atrial Appendage Function in Mitral Stenosis. (who.int)
  • Additionally, AF can also result in other complications, such as adverse hemodynamics, impaired cognitive function or dementia, congestive heart failure and tachycardia-induced cardiomyopathy ( 6 ). (spandidos-publications.com)
  • Heart function improved by up to 25 percent in a trial using gene therapy to reverse cardiac damage from congestive heart failure in a large animal model, Mount Sinai researchers report. (mountsinai.org)
  • Our data suggest that STE might be useful in assessing LA function in dogs with MMVD, and might potentially differentiate dogs with severe subclinical disease from dogs with congestive heart failure. (sonopath.com)
  • Left atrial mechanical functions were evaluated before and after PMV, including left atrial passive emptying volume, LA passive emptying fraction, conduit volume, left ventricular stroke volume, LA active emptying volume, LA active emptying fraction, LA total emptying volume and LA total emptying fraction. (biomedsearch.com)
  • The early increase in conduit volume and the decrease in left atrial presystolic volume indicate that PMV has favorable effects on atrial reservoir and conduit functions. (biomedsearch.com)
  • Data are sufficient to recommend evaluation of left atrial volume in certain populations, and although analysis of atrial reservoir, conduit, and booster pump function trails in that regard, the gap is rapidly closing. (onlinejacc.org)
  • Conduit function is influenced by atrial compliance and is reciprocally related to reservoir function but by necessity is closely related to LV relaxation and compliance. (onlinejacc.org)
  • The left atrium (LA) functions as a reservoir during systole, a conduit during early diastole and an active contractile chamber in late diastole [ 5 , 6 ]. (kjim.org)
  • conduit function i.e. (jcdronline.org)
  • Successful BMV leads to early improvement in left atrial reservoir and conduit functions, without significantly affecting left atrial pump function. (jcdronline.org)
  • SR during ventricular systole (LA-SRs) represents LA reservoir function, and SR during early ventricular diastole (LA-SRe) represents LA conduit function. (elsevier.com)
  • P=0.039), indicating impaired LA conduit function. (umassmed.edu)
  • Kidney function was assessed by estimated glomerular filtration rate (eGFR) calculated using the Modification of Diet in Renal Disease equation, and the presence of proteinuria was measured by a urine dipstick. (clotcare.com)
  • An important cytoprotective enzyme that has been shown to improve renal function is heme-oxygenase (HO). (eurekaselect.com)
  • Atrial receptors and renal function. (springer.com)
  • Renal dysfunction is an independent risk factor for stroke, especially in the setting of atrial fibrillation (AF), and adding it as a scoring element to current risk stratification models, such as CHADS2 , seems to improve stroke risk prediction. (medpagetoday.com)
  • Adherence to the Mediterranean diet is associated with positive renal function in healthy adults. (greenmedinfo.com)
  • A total of 2,753 patients with atrial fibrillation who were anticoagulated using Warfarin and managed by Intermountain Healthcare Clinical Pharmacist Anticoagulation Services - who had a baseline creatinine level of less than 2.0 mg/dL or a glomerular filtration rate greater than 30 and serial renal function studies - were included in the study. (intermountainhealthcare.org)
  • To evaluate the frequency and severity of renal function impairment and the potential impact of using the most common estimates of renal function on the dosing of direct oral anticoagulants (DOACs) among patients with atrial fibrillation (AF) and acute coronary syndrome or a planned percutaneous coronary intervention. (clinpharm-journal.ru)
  • 117.3) μmol/L. The discrepancy between renal function categories assessed using GFR MDRD and GFR CKD-EPI when compared with CrCl was observed in 23.4% and 27.6% of the cases, respectively. (clinpharm-journal.ru)
  • The purpose of the present study was to determine whether endogenous atrial natriuretic factor participates in the maintenance of normal vascular pressure and renal function in ovine fetuses at 128 to 130 days' gestation. (elsevier.com)
  • Fetuses in the low-dose and control groups showed no significant change in cardiovascular or renal function. (elsevier.com)
  • Cheung, CY 1991, ' Role of endogenous atrial natriuretic factor in the regulation of fetal cardiovascular and renal function ', American journal of obstetrics and gynecology , vol. 165, no. 4, pp. 1558-1567. (elsevier.com)
  • New data from a cohort of 13,535 patients (33,165 patient-years of data) indicate that a reduced creatinine clearance and/or proteinuria are associated with an increased risk of stroke in patients with non-valvular atrial fibrillation who were not receiving anticoagulation. (clotcare.com)
  • Twenty seven patients with non-valvular atrial fibrillation (NVAF) and no history of stroke, transient ischaemic attack, dementia, and thyrotoxicosis were compared with 54 age and sex matched controls in sinus rhythm. (tcd.ie)
  • Factors such as advanced age, hypertension, coronary heart disease, prior stroke, and diabetes are recognized risk factors for stroke in patients with atrial fibrillation. (clotcare.com)
  • Despite the efficacy of antithrombotic treatment in preventing stroke in patients with atrial fibrillation, 1 community surveys report a low uptake of such treatment. (bmj.com)
  • Parameters of LA reservoir function i.e. (jcdronline.org)
  • PPaV 1 and PTFV 1 were associated with an increase in LA volumes and decrease in LA emptying fraction and LA reservoir function. (elsevier.com)
  • The aim of this prospective longitudinal study was to identify physiologic effects of reinnervation on changes in heart rate at rest and in response to various stimulations and on atrial function after the Cox maze III procedure. (elsevier.com)
  • BACKGROUND: Patients with mitral stenosis (MS) and heart failure (HF) are characterized by changes in the left atrial (LA) function and activation of the apoptotic process. (ox.ac.uk)
  • Although the clinical impact of left atrial appendage (LAA) leaks still requires confirmation, the open pouch with residual flow resulting from incomplete LAA closure may promote blood sta. (bioportfolio.com)
  • It has been suggested that successful percutaneous balloon mitral valvuloplasty (PMV) decreases the intensity of spontaneous left atrial contrast, reduces the size of the left atrium, and improves left atrial function in patient with mitral stenosis. (biomedsearch.com)
  • Rheumatic mitral stenosis (MS) is associated with progressive impairment of left atrial (LA) mechanical functions. (jcdronline.org)
  • Left atrial function, cytokines and soluble apoptotic markers in mitral stenosis: effects of valvular replacement. (ox.ac.uk)
  • Thromboembolism is one of the most important complications of MS, especially when it is associated with atrial fibrillation (AF).Patients with sinus rhythm (SR) are also sussceptible to this complication when it is associated with left atrial appendage (LAA) dysfunction .LAA dysfunction is an independent predictor of thromboembolism in mitral stenosis. (who.int)
  • Progressive left ventricular (LV) diastolic dysfunction due to hypertension (HTN) alters left atrial (LA) contractile function in a predictable manner. (biomedcentral.com)
  • While increased LA size is a marker of LV diastolic dysfunction and has been shown to be predictive of adverse cardiovascular outcomes, the prognostic significance of altered LA contractile function is unknown. (biomedcentral.com)
  • In hypertensive patients at risk for left ventricular diastolic dysfunction, a decreased contribution of LA contractile function to ventricular filling during diastole is strongly predictive of adverse cardiac events and death. (biomedcentral.com)
  • While evidence exists that LA enlargement is a strong predictor of adverse cardiovascular outcomes in selected populations, there is little data regarding the prognostic implication of altered left atrial contractile function in patients with chronic hypertension at risk of diastolic dysfunction. (biomedcentral.com)
  • These findings support the relationship of LA dysfunction with HFPEF, suggesting that the analysis of LA function may be useful in sinus rhythm patients with new-onset dyspnoea. (nih.gov)
  • Second, all patients were at risk of developing kidney dysfunction, including those who started with healthy kidney function and those who started with moderate-severe kidney disease. (intermountainhealthcare.org)
  • Heart and kidney dysfunction are often correlated with each other, meaning if the function of either organ begins to decline, the other may be adversely affected, causing further organ damage. (intermountainhealthcare.org)
  • Metabolic syndrome (MS) predisposes to left ventricular dysfunction and heart failure , however, alterations in left atrial (LA) function in MS are unknown. (bvsalud.org)
  • Background and Purpose-Edoxaban is a direct oral factor Xa inhibitor with proven efficacy and safety among patients with atrial fibrillation. (elsevier.com)
  • B. Hoit, "Assessment of echocardiographic left atrial size: how accurate do we need to be? (hindawi.com)
  • We tested the hypothesis that LA function index (LAFI), an echocardiographic index of LA structure and function, may better characterize adverse LA remodeling and predict incident AF and CVD than existing measures. (physiciansweekly.com)
  • Left atrial function during pregnancy: a three-dimensional echocardiographic study. (bgu.ac.il)
  • However, whether echocardiographic parameters of LA function, such as LAEF, LAi and MinLAVI, are superior to LAVI for predicting prognosis following STEMI is unknown. (regionh.dk)
  • All subjects underwent conventional echocardiographic examination and assessment of LA function by speckle tracking. (who.int)
  • Although the MAZE procedure allows for the recovery of sinus rhythm and left atrial (LA) mechanical function in the great majority of patients with chronic atrial fibrillation (AF), the effects of MAZE on the precise LA geometry and wall motion remain to be elucidated. (nih.gov)
  • Levels of natriuretic peptides tended to decrease in patients with stable sinus rhythm at one year compared to patients in atrial fibrillation. (diva-portal.org)
  • Left atrial function after the Cox maze procedure improved parallel to the recovery of sinus node function. (elsevier.com)
  • Conclusion: Progressive improvement of sinus node function and atrial contractions with significant functional normalization 1 year after the Cox maze procedure corresponded to functional reinnervation and recovery of the autonomic nervous system. (elsevier.com)
  • The other left atrial volumes were not altered after PMV. (biomedsearch.com)
  • In the 1995 participants (mean age 64.5 years) from the population-based Rotterdam Study, we measured thyroid function (thyroid-stimulating hormone, free thyroxine [FT4]) and performed computed tomography to quantify EAT volumes. (dovepress.com)
  • We report no mediating role of EAT in the association of thyroid function with AF, but found evidence for a suggested interaction of FT4 with EAT volumes on AF risk. (dovepress.com)
  • During simultaneous V/A pacing at 160 beats/min, the reduction in end-diastolic and stroke volumes from the baseline value was -26.6 +/- 3.8 percent and -28.8 +/- 4.3 percent, respectively (both p less than 0.01), but was significantly smaller (-16.1 +/- 3.6 percent and -19.2 +/- 4.1 percent, respectively [p less than 0.05]) when atrial transport was maintained during sequential A-V pacing at the same heart rate. (ucl.ac.uk)
  • During simultaneous V/A pacing at 160 beats/min, two thirds of the reduction in end-diastolic and stroke volumes from the baseline value was due to the increment in heart rate as assessed from sequential A-V pacing and the other third was due to loss of atrial transport. (ucl.ac.uk)
  • The left atrial volumes were calculated by the disk method. (kjim.org)
  • Calculation of LA volumes used in determining LA emptying functions was performed using the biplane area-length method. (biomedcentral.com)
  • Echocardiographically, LA volumes were measured at mitral valve opening (Vmax), at the onset of left atrial systole (P wave of the electrocardiogram, Vp) and at the mitral valve closure (Vmin). (ox.ac.uk)
  • Recent findings suggest that left atrial (LA) function is more strongly related to adverse prognosis than LA volumes. (kb.se)
  • We aimed to evaluate the associations between LA volumes and Doppler filling indices with LA function. (kb.se)
  • CONCLUSION: The risk of AF, including asymptomatic AF, increases significantly with increasing LA volumes and worsening LA function. (regionh.dk)
  • Increasing gestational age results in less ALDAF, and reduced ALDAF contribution to cardiac output likely due to improved diastolic function. (elsevier.com)
  • Background: Alteration of diastolic function is considered a sensitive means for detecting changes in the normal cardiac adaptation to pregnancy. (bgu.ac.il)
  • however, the effect on diastolic function and left atrial (LA) remodeling is unclear. (elsevier.com)
  • The left atrial diameter and volume indices and left atrium / aorta ratio correlated positively with the transmitral flow peak velocity E wave and E wave /IVRT ratio, which are important indices of diastolic function. (bvsalud.org)
  • Background- Changes in neurocognitive function after cardiopulmonary bypass (CPB) are difficult to assess in children with congenital cardiovascular malformations in part because identification of a suitable control group of children is difficult. (ahajournals.org)
  • Left atrial volume predicts cardiovascular events in patients originally diagnosed with lone atrial fibrillation: three-decade follow-up," European Heart Journal , vol. 26, no. 23, pp. 2556-2561, 2005. (hindawi.com)
  • Prediction of cardiovascular outcomes with left atrial size: is volume superior to area or diameter? (hindawi.com)
  • Clinical utility and prognostic value of left atrial volume assessment by cardiovascular magnetic resonance in non-ischaemic dilated cardiomyopathy," European Journal of Heart Failure , vol. 15, no. 6, pp. 660-670, 2013. (hindawi.com)
  • The author examines the ability of left atrial size and function to predict cardiovascular outcomes. (onlinejacc.org)
  • In this state-of-the-art paper, the author reviews the methods used to assess left atrial size and function and discusses their role in predicting cardiovascular events in general and referral populations and in patients with atrial fibrillation, cardiomyopathy, ischemic heart disease, and valvular heart disease. (onlinejacc.org)
  • The resurgence of interest in atrial size and function has enhanced our understanding of the atrial contributions to cardiovascular performance in health and disease. (onlinejacc.org)
  • Among these measurements, maximal left atrial volume (LAV) indexed to body surface area (LAVi) is most strongly associated with cardiovascular disease and is the most sensitive in predicting cardiovascular outcomes and providing uniform and accurate risk stratification (3) . (onlinejacc.org)
  • In 1909, Welch (4) noted that cardiovascular stroke associated with AF was due to left atrial appendage (LAA) thrombi and that this was the most common site for thrombus formation in the setting of AF (5) . (onlinejacc.org)
  • Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study. (physiciansweekly.com)
  • Left atrial (LA) size, a marker of atrial structural remodeling, is associated with increased risk for atrial fibrillation (AF) and cardiovascular disease (CVD). (physiciansweekly.com)
  • It is well known that, as for most cardiovascular disorders, diabetes is an independent risk factor for atrial fibrillation (AF), and that the risk of AF is 1.4 to 2.1 times greater in patients with diabetes than the normal population [ 1 ]. (kjim.org)
  • In humans , left atrial enlargement and reduced contractile functions are associated with adverse cardiovascular events and a poor prognosis in many dilatation of the left atrium occurs with the gradual evolution of chronic mitral valve disease and is well diseases . (bvsalud.org)
  • AIMS: We aimed to investigate whether left atrial (LA) markers from cardiovascular magnetic resonance (CMR) were able to predict atrial fibrillation (AF) in elderly patients with risk factors for stroke. (regionh.dk)
  • Thyroid hormones have substantial effects on the cardiovascular system, and it is well known that overt hyperthyroidism is associated with atrial fibrillation. (bmj.com)
  • Early effects of percutaneous mitral valvuloplasty on left atrial mechanical functions. (biomedsearch.com)
  • However, left atrial mechanical functions immediately after PMV have not been extensively evaluated yet. (biomedsearch.com)
  • The aim of this study was to evaluate the effects of PMV on left atrial mechanical functions. (biomedsearch.com)
  • We hypothesized that LA size and mechanical function in patients with chronic AF and mitral valvular disease are well restored after MAZE. (nih.gov)
  • However, chronic AF associated with mitral valve disease deteriorates LA mechanical function diffusely throughout the LA wall. (nih.gov)
  • The aim of this study was to investigate atrial conduction times and left atrial mechanical functions, the noninvasive predictors of atrial fibrillation, in prediabetic patients with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). (kjim.org)
  • Left atrial mechanical functions were calculated. (kjim.org)
  • In addition, the left atrial mechanical functions were impaired secondary to a deterioration in the diastolic functions in the prediabetic patients. (kjim.org)
  • This study investigated LA conduction times and LA mechanical functions that are predictors of AF and discussed possible mechanisms of AF development in patients with IFG and IGT at a prediabetic stage. (kjim.org)
  • 023). Conclusion: LAA exclusion seems to improve mechanical function of the LA and results in reverse LA remodeling. (elsevier.com)
  • Objective: The aim of this study was to determine the role of left-sided mechanical parameters in postoperative atrial fibrillation (POAF) in patients undergoing coronary artery bypass grafting (CABG). (acibadem.edu.tr)
  • Significant improvement in left atrial function occurs in 7 days. (elsevier.com)
  • The aim of the study LA-EU-01 was to examine the safety and the feasibility of the LAmbreTM Left Atrial Appendage Closure System in patients with non-valvular paroxymal, persistent or perm. (bioportfolio.com)
  • Comparison of Amplatzer Amulet and Watchman Device in Patients Undergoing Left Atrial Appendage Closure. (bioportfolio.com)
  • Left atrial appendage closure (LAAC) is an emerging therapeutic option in non-valvular atrial fibrillation (NVAF) patients with high thromboembolic and bleeding risks. (bioportfolio.com)
  • This study will evaluate thrombogenicity in patients undergoing left atrial appendage closure using the WATCHMAN device. (bioportfolio.com)
  • Intracardiac echography for left atrial appendage closure : A step-by-step tutorial. (bioportfolio.com)
  • Numerous studies have clearly demonstrated the prognostic value of left atrial volume for long-term outcome. (hindawi.com)
  • Effect of bosentan therapy on ventricular and atrial function in adults with Eisenmenger syndrome. (nih.gov)
  • LA C.O.: Left Atrial Cardiac Output. (biomedcentral.com)
  • AF may also worsen heart failure in individuals who are dependent on the atrial component of the cardiac output. (medscape.com)
  • Subclinical hyperthyroidism (that is, reduced serum thyroid stimulating hormone (TSH) concentration but free thyroxine levels within reference ranges) is associated with elevated resting pulse, increased frequency of atrial and ventricular premature beats, increased left ventricular mass index, and cardiac output. (bmj.com)
  • This review article discusses the role of cardiac magnetic resonance and computed tomography in assessment of left atrial size, its normal and abnormal morphology, and function. (hindawi.com)
  • In this elegant study, the authors performed a comprehensive assessment of LV function, showing that extensive LV remodeling at baseline is associated with poor improvement after CRT. (onlinejacc.org)
  • METHODS AND RESULTS: A total of 369 patients with STEMI but without atrial fibrillation or HF who were treated with primary percutaneous coronary intervention were prospectively enrolled in the period between September 2006 and December 2008. (regionh.dk)
  • Percutaneous left atrial appendage (LAA) closure (placement of an occluder to close the appendage) is a novel procedure for stroke prevention in patients suffering from atrial fibrillation. (bioportfolio.com)
  • We sought to provide a practical educational tool for the utilization of intracardiac echography (ICE) in the left atrium for the percutaneous closure of the left atrial appendage (LAA). (bioportfolio.com)
  • CONCLUSION: The present findings indicate that mitral valve replacement in patients with mitral valve stenosis, reduces the size of the left atrium, improves left atrial contractile function and depresses inflammatory and apoptotic process. (ox.ac.uk)