Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.
The chambers of the heart, to which the BLOOD returns from the circulation.
A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
The veins that return the oxygenated blood from the lungs to the left atrium of the heart.
An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)
An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).
Agents that prevent clotting.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Methods to induce and measure electrical activities at specific sites in the heart to diagnose and treat problems with the heart's electrical system.
Ear-shaped appendage of either atrium of the heart. (Dorland, 28th ed)
An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
The period of time following the triggering of an ACTION POTENTIAL when the CELL MEMBRANE has changed to an unexcitable state and is gradually restored to the resting (excitable) state. During the absolute refractory period no other stimulus can trigger a response. This is followed by the relative refractory period during which the cell gradually becomes more excitable and the stronger impulse that is required to illicit a response gradually lessens to that required during the resting state.
Abnormally rapid heartbeats with sudden onset and cessation.
The hemodynamic and electrophysiological action of the HEART ATRIA.
The hemodynamic and electrophysiological action of the LEFT ATRIUM.
The return of a sign, symptom, or disease after a remission.
A type of cardiac arrhythmia with premature atrial contractions or beats caused by signals originating from ectopic atrial sites. The ectopic signals may or may not conduct to the HEART VENTRICLES. Atrial premature complexes are characterized by premature P waves on ECG which are different in configuration from the P waves generated by the normal pacemaker complex in the SINOATRIAL NODE.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)
An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A small nodular mass of specialized muscle fibers located in the interatrial septum near the opening of the coronary sinus. It gives rise to the atrioventricular bundle of the conduction system of the heart.
A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.
Elements of limited time intervals, contributing to particular results or situations.
System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
The use of freezing as a special surgical technique to destroy or excise tissue.
A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
Abnormally rapid heartbeats originating from one or more automatic foci (nonsinus pacemakers) in the HEART ATRIUM but away from the SINOATRIAL NODE. Unlike the reentry mechanism, automatic tachycardia speeds up and slows down gradually. The episode is characterized by a HEART RATE between 135 to less than 200 beats per minute and lasting 30 seconds or longer.
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
Bleeding or escape of blood from a vessel.
Surgery performed on the heart.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
The hemodynamic and electrophysiological action of the RIGHT ATRIUM.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Irregular HEART RATE caused by abnormal function of the SINOATRIAL NODE. It is characterized by a greater than 10% change between the maximum and the minimum sinus cycle length or 120 milliseconds.
A generic expression for any tachycardia that originates above the BUNDLE OF HIS.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The thin membrane-like muscular structure separating the right and the left upper chambers (HEART ATRIA) of a heart.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
The small mass of modified cardiac muscle fibers located at the junction of the superior vena cava (VENA CAVA, SUPERIOR) and right atrium. Contraction impulses probably start in this node, spread over the atrium (HEART ATRIUM) and are then transmitted by the atrioventricular bundle (BUNDLE OF HIS) to the ventricle (HEART VENTRICLE).
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.
Pathological conditions involving the HEART including its structural and functional abnormalities.
The valve between the left atrium and left ventricle of the heart.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.
Long-term changes in the electrophysiological parameters and/or anatomical structures of the HEART ATRIA that result from prolonged changes in atrial rate, often associated with ATRIAL FIBRILLATION or long periods of intense EXERCISE.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
Pyridine derivatives with one or more keto groups on the ring.
Compounds with a BENZENE fused to IMIDAZOLES.
Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The removal or interruption of some part of the autonomic nervous system for therapeutic or research purposes.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A lipid cofactor that is required for normal blood clotting. Several forms of vitamin K have been identified: VITAMIN K 1 (phytomenadione) derived from plants, VITAMIN K 2 (menaquinone) from bacteria, and synthetic naphthoquinone provitamins, VITAMIN K 3 (menadione). Vitamin K 3 provitamins, after being alkylated in vivo, exhibit the antifibrinolytic activity of vitamin K. Green leafy vegetables, liver, cheese, butter, and egg yolk are good sources of vitamin K.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
A group of cardiac arrhythmias in which the cardiac contractions are not initiated at the SINOATRIAL NODE. They include both atrial and ventricular premature beats, and are also known as extra or ectopic heartbeats. Their frequency is increased in heart diseases.
The giving of drugs, chemicals, or other substances by mouth.
Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.
Pathological process resulting in the fibrous obstruction of the small- and medium-sized PULMONARY VEINS and PULMONARY HYPERTENSION. Veno-occlusion can arise from fibrous proliferation of the VASCULAR INTIMA and VASCULAR MEDIA; THROMBOSIS; or a combination of both.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures.
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Formation and development of a thrombus or blood clot in the blood vessel.
Abnormal passage communicating with the ESOPHAGUS. The most common type is TRACHEOESOPHAGEAL FISTULA between the esophagus and the TRACHEA.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Recording the locations and measurements of electrical activity in the EPICARDIUM by placing electrodes on the surface of the heart to analyze the patterns of activation and to locate arrhythmogenic sites.
The venous trunk which returns blood from the head, neck, upper extremities and chest.
Catheters inserted into various locations within the heart for diagnostic or therapeutic purposes.
Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.
The innermost layer of the heart, comprised of endothelial cells.
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
Production of an image when x-rays strike a fluorescent screen.
Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Removal of tissue by vaporization, abrasion, or destruction. Methods used include heating tissue by hot liquids or microwave thermal heating, freezing (CRYOABLATION), chemical ablation, and photoablation with LASERS.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Methods of creating machines and devices.
The confinement of a patient in a hospital.
Small band of specialized CARDIAC MUSCLE fibers that originates in the ATRIOVENTRICULAR NODE and extends into the membranous part of the interventricular septum. The bundle of His, consisting of the left and the right bundle branches, conducts the electrical impulses to the HEART VENTRICLES in generation of MYOCARDIAL CONTRACTION.
Surgical procedures conducted with the aid of computers. This is most frequently used in orthopedic and laparoscopic surgery for implant placement and instrument guidance. Image-guided surgery interactively combines prior CT scans or MRI images with real-time video.
The study of the electrical activity and characteristics of the HEART; MYOCARDIUM; and CARDIOMYOCYTES.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
The study of the heart, its physiology, and its functions.
The hollow, muscular organ that maintains the circulation of the blood.
A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.
Cardiac electrical stimulators that apply brief high-voltage electroshocks to the HEART. These stimulators are used to restore normal rhythm and contractile function in hearts of patients who are experiencing VENTRICULAR FIBRILLATION or ventricular tachycardia (TACHYCARDIA, VENTRICULAR) that is not accompanied by a palpable PULSE. Some defibrillators may also be used to correct certain noncritical dysrhythmias (called synchronized defibrillation or CARDIOVERSION), using relatively low-level discharges synchronized to the patient's ECG waveform. (UMDNS, 2003)
A series of tests designed to assess neuropsychological function. The battery is used to diagnose specific cerebral dysfunction and also to determine lateralization.
Bleeding within the SKULL, including hemorrhages in the brain and the three membranes of MENINGES. The escape of blood often leads to the formation of HEMATOMA in the cranial epidural, subdural, and subarachnoid spaces.
The electrical properties, characteristics of living organisms, and the processes of organisms or their parts that are involved in generating and responding to electrical charges.
Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
Surgical insertion of synthetic material to repair injured or diseased heart valves.
A group of compounds that are derivatives of methoxybenzene and contain the general formula R-C7H7O.
Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.
Blocking of a blood vessel in the SKULL by an EMBOLUS which can be a blood clot (THROMBUS) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with HEART DISEASES. Other non-cardiac sources of emboli are usually associated with VASCULAR DISEASES.
Preliminary administration of a drug preceding a diagnostic, therapeutic, or surgical procedure. The commonest types of premedication are antibiotics (ANTIBIOTIC PROPHYLAXIS) and anti-anxiety agents. It does not include PREANESTHETIC MEDICATION.
Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.
Optical imaging techniques used for recording patterns of electrical activity in tissues by monitoring transmembrane potentials via FLUORESCENCE imaging with voltage-sensitive fluorescent dyes.
Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect.
Injuries caused by electric currents. The concept excludes electric burns (BURNS, ELECTRIC), but includes accidental electrocution and electric shock.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Transmission of the readings of instruments to a remote location by means of wires, radio waves, or other means. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Surgery performed on the thoracic organs, most commonly the lungs and the heart.
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
An adjunctive treatment for PARTIAL EPILEPSY and refractory DEPRESSION that delivers electrical impulses to the brain via the VAGUS NERVE. A battery implanted under the skin supplies the energy.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP.

Electrophysiologic effects of adenosine in patients with supraventricular tachycardia. (1/5583)

BACKGROUND: We correlated the electrophysiologic (EP) effects of adenosine with tachycardia mechanisms in patients with supraventricular tachycardias (SVT). METHODS AND RESULTS: Adenosine was administered to 229 patients with SVTs during EP study: atrioventricular (AV) reentry (AVRT; n=59), typical atrioventricular node reentry (AVNRT; n=82), atypical AVNRT (n=13), permanent junctional reciprocating tachycardia (PJRT; n=12), atrial tachycardia (AT; n=53), and inappropriate sinus tachycardia (IST; n=10). There was no difference in incidence of tachycardia termination at the AV node in AVRT (85%) versus AVNRT (86%) after adenosine, but patients with AVRT showed increases in the ventriculoatrial (VA) intervals (13%) compared with typical AVNRT (0%), P<0.005. Changes in atrial, AV, or VA intervals after adenosine did not predict the mode of termination of long R-P tachycardias. For patients with AT, there was no correlation with location of the atrial focus and adenosine response. AV block after adenosine was only observed in AT patients (27%) or IST (30%). Patients with IST showed atrial cycle length increases after adenosine (P<0.05) with little change in activation sequence. The incidence of atrial fibrillation after adenosine was higher for those with AVRT (15%) compared with typical AVNRT (0%) P<0.001, or atypical AVNRT (0%) but similar to those with AT (11%) and PJRT (17%). CONCLUSIONS: The EP response to adenosine proved of limited value to identify the location of AT or SVT mechanisms. Features favoring AT were the presence of AV block or marked shortening of atrial cycle length before tachycardia suppression. Atrial fibrillation was more common after adenosine in patients with AVRT, PJRT, or AT. Patients with IST showed increases in cycle length with little change in atrial activation sequence after adenosine.  (+info)

Regional differences in the recovery course of tachycardia-induced changes of atrial electrophysiological properties. (2/5583)

BACKGROUND: Regional differences in recovery of tachycardia-induced changes of atrial electrophysiological properties have not been well studied. METHODS AND RESULTS: In the control group (5 dogs), atrial effective refractory period (AERP) and inducibility of atrial fibrillation (AF) were assessed before and every 4 hours for 48 hours after complete atrioventricular junction (AVJ) ablation with 8-week VVI pacing. In experimental group 1 (15 dogs), AERP and inducibility of AF were assessed before and after complete AVJ ablation with 8-week rapid right atrial (RA) pacing (780 bpm) and VVI pacing. In experimental group 2 (7 dogs), AERP and inducibility of AF were assessed before and after 8-week rapid left atrial (LA) pacing and VVI pacing. AERP and inducibility and duration of AF were obtained from 7 epicardial sites. In the control group, atrial electrophysiological properties obtained immediately and during 48-hour measurements after pacing did not show any change. In the 2 experimental groups, recovery of atrial electrophysiological properties included a progressive recovery of AERP shortening, recovery of AERP maladaptation, and decrease of duration and episodes of reinduced AF. However, recovery of shortening and maladaptation of AERP and inducibility of AF was slower at the LA than at the RA and Bachmann's bundle. CONCLUSIONS: The LA had a slower recovery of tachycardia-induced changes of atrial electrophysiological properties, and this might play a critical role in initiation of AF.  (+info)

Effect of 5-HT4 receptor stimulation on the pacemaker current I(f) in human isolated atrial myocytes. (3/5583)

OBJECTIVE: 5-HT4 receptors are present in human atrial cells and their stimulation has been implicated in the genesis of atrial arrhythmias including atrial fibrillation. An I(f)-like current has been recorded in human atrial myocytes, where it is modulated by beta-adrenergic stimulation. In the present study, we investigated the effect of serotonin (5-hydroxytryptamine, 5-HT) on I(f) electrophysiological properties, in order to get an insight into the possible contribution of I(f) to the arrhythmogenic action of 5-HT in human atria. METHODS: Human atrial myocytes were isolated by enzymatic digestion from samples of atrial appendage of patients undergoing coeffective cardiac surgery. Patch-clamped cells were superfused with a modified Tyrode's solution in order to amplify I(f) and reduce overlapping currents. RESULTS AND CONCLUSIONS: A time-dependent, cesium-sensitive increasing inward current, that we had previously described having the electrophysiological properties of the pacemaker current I(f), was elicited by negative steps (-60 to -130 mV) from a holding potential of -40 mV. Boltzmann fit of control activation curves gave a midpoint (V1/2) of -88.9 +/- 2.6 mV (n = 14). 5-HT (1 microM) consistently caused a positive shift of V1/2 of 11.0 +/- 2.0 mV (n = 8, p < 0.001) of the activation curve toward less negative potentials, thus increasing the amount of current activated by clamp steps near the physiological maximum diastolic potential of these cells. The effect was dose-dependent, the EC50 being 0.14 microM. Maximum current amplitude was not changed by 5-HT. 5-HT did not increase I(f) amplitude when the current was maximally activated by cAMP perfused into the cell. The selective 5-HT4 antagonists, DAU 6285 (10 microM) and GR 125487 (1 microM), completely prevented the effect of 5-HT on I(f). The shift of V1/2 caused by 1 microM 5-HT in the presence of DAU 6285 or GR 125487 was 0.3 +/- 1 mV (n = 6) and 1.0 +/- 0.6 mV (n = 5), respectively (p < 0.01 versus 5-HT alone). The effect of 5-HT4 receptor blockade was specific, since neither DAU 6285 nor GR 125487 prevented the effect of 1 microM isoprenaline on I(f). Thus, 5-HT4 stimulation increases I(f) in human atrial myocytes; this effect may contribute to the arrhythmogenic action of 5-HT in human atrium.  (+info)

Effects of cycloprotobuxine-A on atrial fibrillation. (4/5583)

AIM: To study the effects of cycloprotobuxine-A (Cyc-A) on atrial fibrillation. METHODS: Atrial fibrillations in vivo and in vitro were induced by arrhythmogenic drugs. Action potentials were measured by the standard microelectrode technique. RESULTS: Cyc-A, similar to or slightly stronger than amiodarone (Ami), decreased incidences of atrial fibrillation elicited by CaCl2-acetylcholine in mice and increased doses of aconitine, ouabain, or adrenaline to elicit atrial fibrillation in isolated guinea pig atria. Cyc-A 0.3-100 mumol.L-1 decreased the normal automaticity and 0.3-30 mumol.L-1 attenuated or almost abolished the isoprenaline-induced abnormal increase in automaticity in sinus nodal cells. In isolated left atria, Cyc-A 0.3-30 mumol.L-1 inhibited the abnormal rhythmic activity elicited by adrenaline, prolonged action potential duration (APD) and effective refractory period, and reduced excitability. At 3-30 mumol.L-1, Cyc-A also decreased the maximal velocity of depolarization (Vmax). Cyc-A antagonized the acetylcholine-induced shortening of APD. These electrophysiologic effects were similar to those of amiodarone, but Ami did not affect the Vmax. CONCLUSION: Cyc-A produces a protective effect against experimental atrial fibrillation via a prolongation of repolarization, a decease of automaticity, and an inhibition of excitability.  (+info)

Atrioventricular nodal ablation and implantation of mode switching dual chamber pacemakers: effective treatment for drug refractory paroxysmal atrial fibrillation. (5/5583)

OBJECTIVE: To assess the effect of atrioventricular node ablation and implantation of a dual chamber, mode switching pacemaker on quality of life, exercise capacity, and left ventricular systolic function in patients with drug refractory paroxysmal atrial fibrillation. PATIENTS: 18 consecutive patients with drug refractory paroxysmal atrial fibrillation. METHODS: Quality of life was assessed before and after the procedure using the psychological general wellbeing index (PGWB), the McMaster health index (MHI), and a visual analogue scale for cardiac symptoms. Nine of the patients also underwent symptom limited exercise tests and echocardiography to assess left ventricular systolic function. RESULTS: The procedure allowed a reduction in antiarrhythmic drug treatment (p < 0.01). PGWB and symptom scores improved (p < 0.01) but the MHI score did not change. Left ventricular systolic function and exercise capacity were unchanged. CONCLUSIONS: Atrioventricular node ablation and implantation of a DDDR/MS pacemaker is effective treatment for refractory paroxysmal atrial fibrillation, producing improved quality of life while allowing a reduction in drug burden. The popularity of the treatment is justified, but further studies are needed to determine optimum timing of intervention.  (+info)

Predictors of atrial rhythm after atrioventricular node ablation for the treatment of paroxysmal atrial arrhythmias. (6/5583)

OBJECTIVE: To assess the natural history of the atrial rhythm of patients with paroxysmal atrial arrhythmias undergoing atrioventricular node ablation and permanent pacemaker implantation. DESIGN AND SETTING: A retrospective cohort study of consecutive patients identified from the pacemaker database and electrophysiology records of a tertiary referral hospital. PATIENTS: 62 consecutive patients with paroxysmal atrial arrhythmias undergoing atrioventricular node ablation and permanent pacemaker implantation between 1988 and July 1996. MAIN OUTCOME MEASURES: (1) Atrial rhythm on final follow up ECG, classified as either ordered (sinus rhythm or atrial pacing) or disordered (atrial fibrillation, atrial flutter or atrial tachycardia). (2) Chronic atrial fibrillation, defined as a disordered rhythm on two consecutive ECGs (or throughout a 24 hour Holter recording) with no ordered rhythm subsequently documented. RESULTS: Survival analysis showed that 75% of patients progressed to chronic atrial fibrillation by 2584 days (86 months). On multiple logistic regression analysis a history of electrical cardioversion, increasing patient age, and VVI pacing were associated with the development of chronic atrial fibrillation. A history of electrical cardioversion and increasing patient age were associated with a disordered atrial rhythm on the final follow up ECG. CONCLUSIONS: Patients with paroxysmal atrial arrhythmias are at high risk of developing chronic atrial fibrillation. A history of direct current cardioversion.  (+info)

Differential effects of defibrillation on systemic and cardiac sympathetic activity. (7/5583)

OBJECTIVE: To assess the effect of defibrillation shocks on cardiac and circulating catecholamines. DESIGN: Prospective examination of myocardial catecholamine balance during dc shock by simultaneous determination of arterial and coronary sinus plasma concentrations. Internal countershocks (10-34 J) were applied in 30 patients after initiation of ventricular fibrillation for a routine implantable cardioverter defibrillator test. Another 10 patients were externally cardioverted (50-360 J) for atrial fibrillation. MAIN OUTCOME MEASURES: Transcardiac noradrenaline, adrenaline, and lactate gradients immediately after the shock. RESULTS: After internal shock, arterial noradrenaline increased from a mean (SD) of 263 (128) pg/ml at baseline to 370 (148) pg/ml (p = 0.001), while coronary sinus noradrenaline fell from 448 (292) to 363 (216) pg/ml (p = 0.01), reflecting a shift from cardiac net release to net uptake. After external shock delivery, there was a similar increase in arterial noradrenaline, from 260 (112) to 459 (200) pg/ml (p = 0.03), while coronary sinus noradrenaline remained unchanged. Systemic adrenaline increased 11-fold after external shock (p = 0.01), outlasting the threefold rise following internal shock (p = 0.001). In both groups, a negative transmyocardial adrenaline gradient at baseline decreased further, indicating enhanced myocardial uptake. Cardiac lactate production occurred after ventricular fibrillation and internal shock, but not after external cardioversion, so the neurohumoral changes resulted from the defibrillation process and not from alterations in oxidative metabolism. CONCLUSIONS: A dc shock induces marked systemic sympathoadrenal and sympathoneuronal activation, but attenuates cardiac sympathetic activity. This might promote the transient myocardial depression observed after electrical discharge to the heart.  (+info)

Superiority of ibutilide (a new class III agent) over DL-sotalol in converting atrial flutter and atrial fibrillation. The Ibutilide/Sotalol Comparator Study Group. (8/5583)

OBJECTIVE: To compare the efficacy and safety of a single dose of ibutilide, a new class III antiarrhythmic drug, with that of DL-sotalol in terminating chronic atrial fibrillation or flutter in haemodynamically stable patients. DESIGN: Double blind, randomised study. SETTING: 43 European hospitals. PATIENTS: 308 patients (mean age 60 years, 70% men, 48% with heart disease) with sustained atrial fibrillation (n = 251) or atrial flutter (n = 57) (duration three hours to 45 days) were randomised to three groups to receive a 10 minute infusion of 1 mg ibutilide (n = 99), 2 mg ibutilide (n = 106), or 1.5 mg/kg DL-sotalol (n = 103). Infusion was discontinued at termination of the arrhythmia. MAIN OUTCOME MEASURE: Successful conversion of atrial fibrillation or flutter, defined as termination of arrhythmia within one hour of treatment. RESULTS: Both drugs were more effective against atrial flutter than against atrial fibrillation. Ibutilide was superior to DL-sotalol for treating atrial flutter (70% and 56% v 19%), while the high dose of ibutilide was more effective for treating atrial fibrillation than DL-sotalol (44% v 11%) and the lower dose of ibutilide (44% v 20%, p < 0.01). The mean (SD) time to arrhythmia termination was 13 (7) minutes with 2 mg ibutilide, 19 (15) minutes with 1 mg ibutilide, and 25 (17) minutes with DL-sotalol. In all patients, the duration of arrhythmia before treatment was a predictor of arrhythmia termination, although this was less obvious in the group that received 2 mg ibutilide. This dose converted almost 48% of atrial fibrillation that was present for more than 30 days. Concomitant use of digitalis or nifedipine and prolongation of the QTc interval were not predictive of arrhythmia termination. Bradycardia (6.5%) and hypotension (3.7%) were more common side effects with DL-sotalol. Of 211 patients given ibutilide, two (0.9%) who received the higher dose developed polymorphic ventricular tachycardia, one of whom required direct current cardioversion. CONCLUSION: Ibutilide (given in 1 or 2 mg doses over 10 minutes) is highly effective for rapidly terminating persistent atrial fibrillation or atrial flutter. This new class III drug, under monitored conditions, is a potential alternative to currently available cardioversion options.  (+info)

Atrial fibrillation is the most common arrhythmia and accounts for one-third of hospitalizations for rhythm disorders in the United States. The prevalence of atrial fibrillation averages 1% and increases with age. With the aging of the population, the number of patients with atrial fibrillation is expected to increase 150% by 2050, with more than 50% of atrial fibrillation patients being over the age of 80. This increasing burden of atrial fibrillation will lead to a higher incidence of stroke, as patients with atrial fibrillation have a five- to sevenfold greater risk of stroke than the general population. Strokes secondary to atrial fibrillation have a worse prognosis than in patients without atrial fibrillation. Vitamin K antagonists (e.g., warfarin), direct thrombin inhibitors (dabigatran), and factor Xa inhibitors (rivaroxaban and apixaban) are all oral anticoagulants that have been FDA approved for the prevention of stroke in atrial fibrillation. This review will summarize the
Preface, vii List of contributors, ix. VeniceChart task force composition, xxxiii. List of abbreviations, xxxvii. 1 Anatomy of structures relevant to atrial fibrillation ablation, 1. 2 Pathophysiology of atrial fibrillation, 20. 3 Techniques and technologies for atrial fibrillation catheter ablation, 35. 4 Endpoints of catheter ablation for atrial fibrillation, 61. 5 Patient management pre-, during-, and postablation, 70. 6 Periprocedural and long-term anticoagulation, 77. 7 Periprocedural and late complications, 85. 8 Short- and long-term efficacy of catheter ablation procedures for atrial fibrillation, 118. 9 Indications to atrial fibrillation ablation and cost-effectiveness, 127. 10 Clinical trials on atrial fibrillation/future perspectives, 137. 11 Surgical approach/ablation, 161. 12 Hospital equipment and facilities, personnel, training requirements, and competences, 176. Index, 184. ...
I review the present understanding of thromboembolic complications and their prevention in patients with nonrheumatic atrial fibrillation. Chronic atrial fibrillation carries an annual 3-6% risk of thromboembolic complications, which is 5-7 times greater than that of controls with sinus rhythm. Paroxysmal atrial fibrillation is associated with a lower risk of thromboembolic complications than chronic atrial fibrillation. Heart failure and systemic hypertension seem to be significant clinical risk factors for stroke in patients with atrial fibrillation, but disagreement persists, and, with few exceptions, subgroups at particular risk have not been convincingly identified. The risk of stroke in persons with thyrotoxic atrial fibrillation seems to be lower than believed previously. Clinical studies have shown that left atrial dilatation is a consequence of the duration of atrial fibrillation rather than a cause, but the relation of left atrial enlargement to stroke is uncertain. Cerebral blood flow ...
Atrial fibrillation is a common cause of stroke and other morbidity. Adequate treatment with anticoagulants reduces the risk of stroke by 60 %. Early detection and treatment of atrial fibrillation could prevent strokes. Atrial fibrillation is often asymptomatic and/or paroxysmal. Case-finding with pulse palpation is an effective screening method, but new methods for detecting atrial fibrillation have been developed. To detect paroxysmal atrial fibrillation ambulatory rhythm recording is needed. This study aims to determine the yield of case-finding for atrial fibrillation in primary care patients. In addition, it will determine the diagnostic accuracy of three different case-finding methods. In a multicenter cluster randomised controlled trial, we compare an enhanced protocol for case-finding of atrial fibrillation with usual care. We recruit 96 practices. We include primary care patients aged 65 years or older not diagnosed with atrial fibrillation. Within each practice, a cluster of 200 patients is
Most current treatment guidelines recommend warfarin therapy for patients with atrial fibrillation who are older than 60 years.24 25 In our study only 11% of patients did not have at least one additional vascular risk factor beyond atrial fibrillation and age. This means that most of our patients were at moderate to high risk for stroke.21 This finding is similar to the Cardiovascular Health Study, in which only 8% of patients with atrial fibrillation older than 65 years did not have evidence of cardiovascular disease,39 and the pooled data from the atrial fibrillation trials, in which 15% of patients had no vascular risk factors other than atrial fibrillation.21 Our primary analysis was based on those at moderate to high risk for stroke. Among these patients, there is little controversy among consensus statements and guidelines.14 25 40 Our principal finding is that 60% of patients with atrial fibrillation who are good candidates for anticoagulation (atrial fibrillation plus at least one other ...
Newly diagnosed Atrial Fibrillation patients have many questions about living with A-Fib. These are answers to the most frequently asked questions by patients and their families. (Click on the question to jump to the answer). 1. Cause: Did I cause my Atrial Fibrillation? Am I responsible for getting A-Fib?. 2. Severity: My doctor says I had an attack of Atrial Fibrillation. How much trouble am I in?. Related Question: Is Atrial Fibrillation a prelude to a heart attack?. Related Question: Can I die from my Atrial Fibrillation? Is it life threatening?. 3. Anomaly? Could my Atrial Fibrillation go away on its own? I dont want to take any medication. Can I just wait and see?. Related Question: Is it possible to have a single Atrial Fibrillation attack and not have any others? I had a single episode of A-Fib and was successfully converted in the ER with meds.. Related Question: How can I tell when Im in A-Fib or just having something like indigestion?. 4. Sex/Exercise: Should I cool ...
Previous data on spontaneous conversion of atrial fibrillation to sinus rhythm have been derived from smaller series that focused on the utility of specific AV node blocking agents or antiarrhythmic medications for promoting cardioversion. With the possible exception of sotalol, agents such as digoxin, beta-adrenergic receptor antagonists or calcium channel blockers are effective for ventricular rate control but ineffective for converting atrial fibrillation to sinus rhythm [20-25]. Previously, Falk and colleagues [8], examining the efficacy of digoxin for converting atrial fibrillation in a study of 36 patients, reported that 44% of the patients in the placebo arm had spontaneous conversion, compared with 50% of patients randomized to digoxin. Similar results were recently reported by the Digitalis in Acute Atrial Fibrillation (DAAF) investigators [12]. In that multicenter prospective study of digoxin versus placebo for conversion of recent atrial fibrillation, there was no significant ...
Introduction Catheter ablation (CA) for atrial fibrillation (AF) is growing exponentially. Although ablation for paroxysmal AF (PAF) is associated with shorter procedure times and less extensive left atrial ablation vs persistent AF thromboembolic complications can occur in both sub-groups. Inadequate anticoagulation leads to thrombotic complications and excessive anticoagulation can lead to bleeding risks. Many centres adopt a policy of discontinuing warfarin in the immediate run-up to the procedure, covering the procedure with unfractionated heparin and bridging postoperative patients with low molecular weight heparins (LMWH) back onto warfarin. We wished to determine the safety of CA for AF with a therapeutic INR using both the single transseptal approach and duty cycled radiofrequency energy (RF) with non irrigated PVAC catheters and the double transseptal puncture technique using irrigated RF catheters and either CARTO or NAVX electroanatomical mapping. ...
OBJECTIVE Diabetes has long been recognized as a risk factor for atrial fibrillation, but its independent contribution to atrial fibrillation has not been fully evaluated. We sought to compare the prevalence and incidence of atrial fibrillation in age- and sex-matched patients with and without type 2 diabetes.. RESEARCH DESIGN AND METHODS Using an observational cohort design, we selected 10,213 members of an HMO diabetes registry as of 1 January 1999 plus 7,159 patients who entered the registry by 31 December 2004 and matched them to patients without diabetes on year of birth and sex. All patients were followed until they died, left the health plan, or until 31 December 2008. We compared the baseline prevalence of atrial fibrillation and then followed patients without atrial fibrillation to compare atrial fibrillation incidence while controlling for known risk factors.. RESULTS Atrial fibrillation prevalence was significantly greater among patients with diabetes (3.6 vs. 2.5%, P , 0.0001). Over ...
Atrial Fibrillation patients often have loads of Why? and How? questions. Here are answers to the most frequently asked questions by patients and their families. (Click on the question to jump to the answer.). 1. Causes: Why does so much Atrial Fibrillation come from the Pulmonary Vein openings?. Related Question: Why do older people get Atrial Fibrillation more than younger people?. Related Question: What causes Paroxysmal A-Fib to turn into Persistent (Chronic) A-Fib?. Related Question: A-Fib and Flutter-I have both. Does one cause the other?. 2. Hereditary: Is my Atrial Fibrillation genetic? Will my children get A-Fib too?. 3. PSVT: Is Atrial Fibrillation (A-Fib) different from what doctors call Paroxysmal Supraventricular Tachycardia?. 4. Adrenergic/Vagal: What is the difference between Adrenergic and Vagal Atrial Fibrillation? How can I tell if I have one or the other? Does it really matter? Does Pulmonary Vein Ablation (Isolation) work for Adrenergic and/or Vagal ...
BACKGROUND: The incidence of atrial fibrillation (AF) among patients undergoing left ventricular assist device (LVAD) implantation is high. However, the impact of AF on clinical outcomes has not been clarified. We reviewed our 9-year experience of continuous flow (CF) LVADs to determine the impact of preoperative AF on stroke, device thrombosis, and survival. METHODS: Between March 2006 and May 2015, 231 patients underwent implantation of 240 CF LVADs, 127 (52.9%) as bridge to transplantation and 113 (47.1%) as destination therapy. Effect of AF on postoperative outcomes was assessed by using Kaplan-Meier survival and Cox proportional hazard regression. RESULTS: There were 78 patients (32.5%) with preoperative AF with a mean age of 55.7 ± 11.4 years. A similar incidence of stroke was found in patients with and without AF, 12.8% versus 16.0%, respectively (p = 0.803). Survival was similar, with 1-, 6-, 12-, and 24-month survivals of 96.2%, 91.7%, 84.5%, and 69.2%, respectively, for AF patients, versus 93
The current study is, to the best of our knowledge, the first to assess the association between the whole spectrum of thyroid disease and the subsequent risk of atrial fibrillation in a population of primary care patients. Our main finding was an apparent linear relation between levels of thyroid dysfunction and atrial fibrillation risk-that is, a low atrial fibrillation risk in hypothyroid patients, a high risk in hyperthyroidism, and a TSH level dependent (a dose-response relation) increased risk of atrial fibrillation in all levels of hyperthyroid disease, even in high normal euthyroid subjects. Notably, in subjects with reduced serum TSH levels but normal free thyroid hormone levels the risk of developing atrial fibrillation was increased approximately 10% in individuals with high normal thyroid function and increased about 40% in those with subclinical hyperthyroidism with suppressed TSH levels (table 4⇑, fig 3⇑). Overall, the relative risk of atrial fibrillation associated with thyroid ...
article{3aabedf9-a573-45ce-ab4a-dcc4e7a6b467, abstract = {,p,Background Electrical cardioversion of atrial fibrillation is associated with an increased risk of embolic stroke, but is generally considered safe if performed within 48 h after onset. Our objective was to investigate if thromboembolism and bleeding in association with cardioversion of atrial fibrillation differed between patients with and without oral anticoagulation. Methods Retrospective study of patients with atrial fibrillation undergoing electrical cardioversion from national Swedish health registries from January 1st 2006 until December 1st 2010. Main outcome measures were thromboembolism and bleeding. Results In total 22,874 atrial fibrillation patients underwent electrical cardioversion, 10,722 with and 12,152 without oral anticoagulation pre-treatment. Patients with low stroke risk (CHA,sub,2,/sub,DS,sub,2,/sub,-VASc 0-1) did not suffer from any thromboembolic complications within 30 days after cardioversion. After ...
Researchers at Western University hope their systematic review of almost 12,000 patients will raise awareness among physicians about the need for more extensive testing for atrial fibrillation, or heart rhythm disturbances, following a stroke or transient ischemic attack (TIA).. The review, published by Lancet Neurology, analyzed the results of 50 studies from four continents and showed that almost 24 per cent of stroke patients with no history of atrial fibrillation can be newly diagnosed with atrial fibrillation when using multiple cardiac monitoring methods sequentially. Thats more than twice higher than previous estimates which are based on only one or two methods of diagnosis.. We found that by using a sequential combination of different cardiac monitoring methods, the number of ischemic stroke and TIA patients newly diagnosed with atrial fibrillation can be increased considerably, said Dr. Luciano Sposato, a recently recruited Associate Professor of Neurology at Westerns Schulich ...
Atrial fibrillation (AF) is the most common cardiac rhythm disorder worldwide, and is gaining in prevalence. Currently, the treatment for atrial fibrillation is concentrated on patients with existing atrial fibrillation, and the reduction in risks of complications of stroke with anticoagulation. Furthermore, mechanical interventions such as atrial ablation procedures are fraught with inconsistent results. The availability of serum based biomarkers that can predict the early onset of atrial fibrillation, and also the ability to prognosticate risk, may help in the identification of patients at risk for AF complications early. This would also allow the identification of the patient population most suitable for the evaluation of possible future intervention strategies to prevent the onset of atrial fibrillation, and alter its natural history and complications.. Currently the best biomarkers in predicting atrial fibrillation risk are in fact markers for heart failure - NTproBNP and high sensitivity ...
Atrial fibrillation is a condition in which the hearts upper chambers, the atria, contract at an abnormally rapid rate. It is a common type of arrhythmia, and occurs in 1-2% of the general population. The prevalence of atrial fibrillation increases with age. Between 50 and 70% of patients with atrial fibrillation lasting ,48 hours spontaneously convert to normal sinus rhythm, and drug therapy increases the likelihood of conversion to sinus rhythm. Another treatment option for conversion of atrial fibrillation and atrial flutter is electrical conversion. This is an effective treatment but requires anesthesia.. Current treatment strategy for medical conversion of atrial fibrillation and atrial flutter is to employ drugs that affect ion channel activity in atrial cardiomyocytes. However, such converting drugs all have potentially serious side effects and are expensive. Potassium, sodium, calcium, and magnesium molecules are the most important ions causing electric current in the heart tissue. Our ...
Headline: Bitcoin & Blockchain Searches Exceed Trump! Blockchain Stocks Are Next!. Atrial Fibrillation Therapeutics market report covers research informatics related to Atrial Fibrillation Therapeutics clinical trials, such as a listing of industry and sponsored clinical trials as well as new drug therapies.. Designed to be a resource both for patients interested in participating in Atrial Fibrillation Therapeutics clinical trials and for research professionals.. The report, Atrial Fibrillation Therapeutics Global Clinical Trials Review, H2, 2016″ provides an overview of Atrial Fibrillation Therapeutics clinical trials scenario. This report provides top line data relating to the clinical trials on Atrial Fibrillation Therapeutics. Report includes an overview of trial numbers and their average enrolment in top countries conducted across the globe. The report also offers coverage of disease clinical trials by region, country (G7 & E7), phase, trial status, end points status and sponsor ...
We sought to determine how well PACs predict atrial fibrillation compared to an established but substantially more complex prediction model derived from the Framingham Heart Study, said senior author Gregory Marcus, MD, MAS, an associate professor of medicine who specializes in electrophysiology in the UCSF Division of Cardiology. Because PACs may themselves have a causal relationship with atrial fibrillation, it is theoretically possible that their eradication, such as through drugs or a catheter ablation procedure, could actually modify atrial fibrillation risk. People who have atrial fibrillation may not show any symptoms, but the condition can increase ones risk of heart failure or stroke. Atrial fibrillation occurs when rapid, random electrical signals cause the atria to contract irregularly and quickly. Marcus and his colleagues studied a random sample of individuals 65 years and older who underwent 24-hour Holter monitoring as part of the national Cardiovascular Health Study from 1989 ...
Oxidative stress is involved in the pathogenesis of congestive heart failure (CHF). Some trace elements serve as antioxidant defenses. The purpose of this study was to analyze the effect of atrial fibrillation (AF) on zinc (Zn) and copper (Cu) levels in patients with advanced CHF. In this prospectiv …
TY - JOUR. T1 - Postoperative atrial fibrillation in noncardiothoracic surgical patients. AU - Christians, Kathleen K.. AU - Wu, Bobby. AU - Quebbeman, Edward J.. AU - Brasel, Karen J.. PY - 2001/12/1. Y1 - 2001/12/1. N2 - Background: Atrial fibrillation is a common arrhythmia whose prevalence increases with age. It is a well-known complication of cardiothoracic surgery, but the incidence and contributing factors to the development of atrial fibrillation in noncardiothoracic surgical patients are less well known. This study was undertaken to investigate the incidence, association with known risk factors, treatment, and outcome of atrial fibrillation in postoperative noncardiac, nonthoracic surgical patients. Methods: A 2-year retrospective review was performed of all noncardiac, nonthoracic surgical patients that developed atrial fibrillation within 30 days of operation. Incidence, risk factors, treatment and outcome related to the development of this arrhythmia were analyzed. Results: Fifty-one ...
Anticoagulation therapy is an important method of preventing stroke in individuals with atrial fibrillation (AF). Atrial fibrillation is a quivering or irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart-related complications. Clinical guidelines on AF consistently recommend long-term oral warfarin to treat valvular atrial fibrillation (VAF). However, due to varying risks of blood clots and stroke associated with different types of non-valvular atrial fibrillation NVAF, it is unclear whether direct oral anticoagulant (DOAC) can replace warfarin. Despite a recent increase in evidence on the effectiveness and the importance of anticoagulant therapy in preventing thromboembolic events associated with NVAF, clinical prevention strategies remain complex. Given the complexities associated with clinical use of anticoagulants for patients with NVAF, this review aims to offer guidance on patient anticoagulant use based on current available evidence.
Aims To test the ability of four circulating biomarkers of fibrosis, and of low left atrial voltage, to predict recurrence of atrial fibrillation after catheter ablation. Background Circulating biomarkers potentially may be used to improve patient selection for atrial fibrillation ablation. Low voltage areas in the left atrium predict arrhythmia recurrence when mapped in sinus rhythm. This study tested type III procollagen N terminal peptide (PIIINP), galectin-3 (gal-3), fibroblast growth factor 23 (FGF-23), and type I collagen C terminal telopeptide (ICTP), and whether low voltage areas in the left atrium predicted atrial fibrillation recurrence, irrespective of the rhythm during mapping. Methods 92 atrial fibrillation ablation patients were studied. Biomarker levels in peripheral and intra-cardiac blood were measured with enzyme-linked immunosorbent assay. Low voltage (,0.5mV) was expressed as a proportion of the mapped left atrial surface area. Follow-up was one year. The primary endpoint was ...
PAFIB - Paroxysmal atrial fibrillation. Looking for abbreviations of PAFIB? It is Paroxysmal atrial fibrillation. Paroxysmal atrial fibrillation listed as PAFIB
Best Syndication New) - Researchers from the University of California, San Francisco (UCSF) and the Kaiser Permanente Northern California Division of Research, found an increased risk for kidney failure in people who have atrial fibrillation and chronic kidney disease. In general, kidney function can fail over time with the chronic condition which can lead to dialysis treatments or a kidney transplant. Kidney problems are more likely to worsen in atrial fibrillation patients who already have kidney function impairment. The study results were published in the journal Circulation.. Irregular heart rhythm is a very common type of atrial fibrillation. Patients who have atrial fibrillation along with chronic kidney disease or end stage-renal disease (ESRD) are at an increased risk for suffering from a stroke or death. The researchers wanted to understand why atrial fibrillation patients with kidney disease are more likely to have end-stage renal disease compared to those with chronic kidney disease ...
TY - JOUR. T1 - Ablation of atrial fibrillation during coronary artery bypass grafting. T2 - Late outcomes in a Medicare population. AU - Malaisrie, S. Chris. AU - McCarthy, Patrick M.. AU - Kruse, Jane. AU - Matsouaka, Roland A.. AU - Churyla, Andrei. AU - Grau-Sepulveda, Maria V.. AU - Friedman, Daniel J.. AU - Brennan, J. Matthew. PY - 2020/1/1. Y1 - 2020/1/1. N2 - Background: This study compares outcomes of patients with preoperative atrial fibrillation undergoing coronary artery bypass grafting (CABG) with or without concomitant atrial fibrillation ablation in a nationally representative Medicare cohort. Objectives: This study examined early and late outcomes in CABG patients with a preoperative history of atrial fibrillation to determine the correlation between surgical atrial fibrillation ablation to mortality and stroke or systemic embolization. Methods: In the Medicare-linked Society of Thoracic Surgeons database, 361,138 patients underwent isolated CABG from 2006 to 2013; 34,600 (9.6%) ...
About Atrial FibrillationGenerally speaking, in Atrial fibrillation, the heart muscles start to beat faster and in an uncoordinated fashion. This disrupts the smooth flow of blood with the result that blood accumulates in the heart chambers.Atrial Fibrillation can be a brief transient condition, or it can become chronic. AF can interrupt smooth blood flow, increasing the risk of accumulation of clots that can cause organ damage or stroke. The hearts ability to pump blood can also deteriorate, leading to heart failure.Signs and Symptoms:Palpitations, awareness of a rapid and irregular heartbeatFatigueDizziness, and faintingShortness of breathAngina (chest pain due to the reduced blood flow to the heart muscles)What causes Atrial Fibrillation?There are many risk factors for developing Atrial fibrillation. These include: increased age (1% of people over 60 years of age have Atrial fibrillation), high blood pressure, mitral valve malfunction, an overactive thyroid gland, low amounts of oxygen in the blood,
Atrial fibrillation is the most common arrhythmia in patients visiting a primary care practice. Although many patients with atrial fibrillation experience relief of symptoms with control of the heart rate, some patients require restoration of sinus rhythm. External direct current (DC) cardioversion is the most effective means of converting atrial fibrillation to sinus rhythm. Pharmacologic cardioversion, although less effective, offers an alternative to DC cardioversion. Several advances have been made in antiarrhythmic medications, including the development of ibutilide, a class III antiarrhythmic drug indicated for acute cardioversion of atrial fibrillation. Other methods of pharmacologic and nonpharmacologic cardioversion remain under development. Until the results of several large-scale randomized clinical trials are available, the decision to choose cardioversion or maintenance of sinus rhythm must be individualized, based on relief of symptoms and reduction of the morbidity and mortality
Sophia Antipolis, 10 Oct 2017: Novel smartphone and tablet applications (apps) for atrial fibrillation patients and healthcare professionals have been launched by heart experts. The objectives and design of the apps are outlined in a paper published online today in EP Europace(1), with a summary published in the European Heart Journal (2).. Atrial fibrillation is the most common heart rhythm disorder and significantly increases the risk of stroke and death. One in four middle-aged adults in Europe and the US will develop atrial fibrillation, and the incidence and prevalence are rising.. Around two-thirds of people in Europe and the US have a mobile device and use it as their main way of accessing online information, said lead author Dr Dipak Kotecha, a clinician scientist in cardiovascular medicine at the Institute of Cardiovascular Sciences, University of Birmingham, UK. This presents a big opportunity to improve self management and shared decision making in atrial fibrillation.. The My AF ...
A new clinical trial is now underway at the Massachusetts General Hospital to investigate whether combining two endovascular catheter-based procedures will improve the long-term outcome in the treatment of atrial fibrillation, the most common heart rhythm disorder. Mass General is the first hospital in New England - and only the second in the nation - to pair renal artery sympathetic denervation with pulmonary vein isolation (PVI) for patients with atrial fibrillation and hypertension.. Typically these procedures are done separately, said Moussa Mansour, MD, director of the Atrial Fibrillation Program in the Mass General Institute for Heart, Vascular and Stroke Care. In this trial, renal denervation is not only performed to treat the patients hypertension, which is the usual goal of the procedure, but as an adjunct to PVI to improve the outcome of atrial fibrillation ablation. We see real potential in this treatment for patients who continue to experience atrial fibrillation symptoms in ...
TY - JOUR. T1 - Stroke prevention in atrial fibrillation. AU - Katsnelson, Michael. AU - Koch, Sebastian. AU - Rundek, Tatjana. PY - 2010/10/1. Y1 - 2010/10/1. N2 - Non-valvular atrial fibrillation is a common and from a neurological perspective the most significant cardiac arrhythmia with a growing world-wide incidence. It also carries a significant associated morbidity and mortality, with cardioembolic strokes arguably being the most disabling sequelae. This brief review will highlight the important studies and the latest treatment modalities available for stroke prevention in patients with non-valvular atrial fibrillation.. AB - Non-valvular atrial fibrillation is a common and from a neurological perspective the most significant cardiac arrhythmia with a growing world-wide incidence. It also carries a significant associated morbidity and mortality, with cardioembolic strokes arguably being the most disabling sequelae. This brief review will highlight the important studies and the latest ...
The data show that there is no survival benefit to the strategy of rhythm control in elderly patients with atrial fibrillation. Indeed there were trends toward higher rates of death and stroke among patients treated with rhythm control. Rate control appears to be an acceptable primary strategy in patients with atrial fibrillation. Long term anticoagulation appears warranted in all patients with risk factors for stroke. Risk factors for ischemic stroke in nonvalvular AF include prior thromboembolism, CHF, HTN, age, DM, female gender, BP greater than 160 mmHg and LV dysfunction. As stated in the ACC/AHA guidelines, maximum protection against ischemic stroke in AF is probably achieved with an international normalized ratio (INR) of 2 to 3, whereas an INR range of 1.6 to 2.5 appears to be associated with incomplete efficacy, estimated at approximately 80% of that achieved with higher intensity anticoagulation. ACC/AHA guidelines recommend that physicians individualize the selection of the ...
Atrial fibrillation is a heterogeneous disorder that is usually characterized by paroxysmal onset, particularly in patients without structural heart disease. Defining biological markers of atrial remodelling would help identify patients at high risk who would benefit most from prophylactic treatment and careful monitoring. Biomarkers of atrial fibrillation progression would be helpful for following patients that present with asymptomatic atrial fibrillation. Notably, the roles of such markers in the pathophysiology of atrial fibrillation must be determined. Some markers may indicate the presence, complications or progression of the disease, while others may be involved in key pathological processes and thus represent novel therapeutic targets. Although a number of markers have been reported as potential predictors of paroxysmal atrial fibrillation progression towards persistent arrhythmia, their usefulness and clinical value need further validation. This report reviews several newly identified markers
Doctors at Washington University School of Medicine in St. Louis are performing a new procedure to treat atrial fibrillation, a common irregular heartbeat.. Available at only a handful of U.S. medical centers, this hybrid procedure combines minimally invasive surgical techniques with the latest advances in catheter ablation, a technique that applies scars to the hearts inner surface to block signals causing the heart to misfire. The two-pronged approach gives doctors access to both the inside and outside of the heart at the same time, helping to more completely block the erratic electrical signals that cause atrial fibrillation.. Atrial fibrillation affects more than 2 million Americans, a number that continues to increase as the population ages. While not fatal in itself, patients who suffer from atrial fibrillation are at increased risk of stroke and congestive heart failure. And many, especially those who feel the fibrillations, have shortness of breath, chest pain, fatigue and feelings of ...
Why is Atrial Fibrillation Atrial Fibrillation (AF or AFib) a Problem? The American Heart Association explains the consequences of atrial fibrillation, the causes of afib, the risks of afib, how atrial fibrillation may cause a stroke, how afib may cause heart failure and how afib may cause additional heart rhythm problems.
We assessed baseline differences between the exposure and control groups using χ2 tests for categorical variables and t tests for continuous variables. Crude incidence rates of stroke or TIA (primary outcome) and crude all cause mortality (secondary outcome) were calculated in patients with resolved atrial fibrillation, atrial fibrillation, and no atrial fibrillation. We calculated crude and adjusted incidence rate ratios comparing the incidence of stroke or TIA and mortality in patients with resolved atrial fibrillation versus those with and without atrial fibrillation.. Poisson regression was used to calculate adjusted incidence rate ratios, adjusting for the baseline covariates age, sex, Townsend deprivation fifth, body mass index (BMI), smoking status (current smoker), alcohol consumption (non-drinker, drinker, excessive drinker), Charlson comorbidity index category, current statin prescription, and current anticoagulant prescription. A sensitivity analysis was carried out in which we ...
The concept that atrial fibrillation begets atrial fibrillation might have some important clinical implications. First of all it emphasizes that most of our electrophysiological knowledge stems from acute experiments and that we know relatively little about chronic electrophysiological adaptation processes. If it is true that the long-term shortening of atrial refractoriness during fibrillation is based on a fundamental change in composition of the ion channels responsible for repolarization of the atrial cells, the action of antiarrhythmic drugs on fibrillating atria may be different than the effects as measured during sinus rhythm. The clinically observed diminished efficacy of chemical cardioversion after a prolonged period of atrial fibrillation9 10 11 12 might be explained by such a process of electrical remodeling. In fact it might be imperative to reevaluate the effects of existing anti-fibrillatory drugs in chronically fibrillating hearts. On the other hand it opens the possibility to ...
Our study demonstrates that in dyspneic patients without HF, permanent/paroxysmal AF is associated with increased circulating BNP levels. This pattern was not evident in patients with a final diagnosis of HF. Although the overall diagnostic performance of BNP for HF tended to be lower in patients with AF than in those without, BNP performed well in both groups. Our data also demonstrate that the conventional cutoff value of 100 pg/ml was associated with a markedly lower specificity and positive likelihood ratio in patients with AF than in those without, suggesting that a higher diagnostic threshold should be used to diagnose HF in patients with AF.. The most widely accepted indication for BNP measurement in clinical practice is for the emergency diagnosis of HF in patients presenting with acute dyspnea. The first study suggesting that BNP measurement could prove useful in this setting was published 10 years ago (20). However, clinical use of this test was limited until the publication of the ...
In this paper, R wave peak interval independent atrial fibrillation detection algorithm is proposed based on the analysis of the synchronization feature of the electrocardiogram signal by a deep neural network. Firstly, the synchronization feature of each heartbeat of the electrocardiogram signal is constructed by a Recurrence Complex Network. Then, a convolution neural network is used to detect atrial fibrillation by analyzing the eigenvalues of the Recurrence Complex Network. Finally, a voting algorithm is developed to improve the performance of the beat-wise atrial fibrillation detection. The MIT-BIH atrial fibrillation database is used to evaluate the performance of the proposed method. Experimental results show that the sensitivity, specificity, and accuracy of the algorithm can achieve 94.28%, 94.91%, and 94.59%, respectively. Remarkably, the proposed method was more effective than the traditional algorithms to the problem of individual variation in the atrial fibrillation detection ...
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Arterial hypertension (HTN) and atrial fibrillation often coexist and the combination of these two conditions carries an increased risk of stroke. HTN is one of the most important risk factors included in the scores for stoke prediction in atrial fibrillation used to assess the need of anticoagulation, and HTN has also been strictly related to bleeding complications of antithrombotic therapy. Antithrombotic drugs options include vitamin K antagonists, or new oral anticoagulants, recently approved for stroke prevention in nonvalvular atrial fibrillation. More favorable new oral anticoagulant efficacy and safety, compared with warfarin, have been reported in hypertensive patients, making these drugs a first-line choice in this population to prevent cerebrovascular events and reduce the risk of major bleedings. The aim of this review is to explore the relationship among HTN, atrial fibrillation and the risk of stroke and to summarize the evidence on the impact of HTN on the choice of the most ...
Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: The Losartan Intervention for End point reduction in hypertension (LIFE) study Academic Article ...
The most common arrhythmia in older adults is atrial fibrillation, with an estimated prevalence of ≈9% in adults aged ≥80 years and a concomitant increased burden of developing stroke. Additionally, over the past decade, both the incidence and prevalence of atrial fibrillation has markedly increased1 and, with it, the total number of patients potentially requiring long-term oral anticoagulation therapy for the prevention of stroke and systemic embolism. In 2009, the estimated number of atrial fibrillation diagnoses in the United States was 2 643 000, with equal distribution between men and women and 82% at ages ≥65 years, with that number increasing 10% between 1999 to 2005.2 The magnitude of the problem is exemplified by the fact that the risk of stroke in patients with atrial fibrillation increases with age and accounts for ≈45% of embolic strokes, approximately 100 000 annually in the United States.3. Article see p 138. The advent of the novel oral anticoagulants has strikingly ...
TY - JOUR. T1 - Effect of Early Direct Current Cardioversion on the Recurrence of Atrial Fibrillation in Patients With Persistent Atrial Fibrillation. AU - Osmanagic, Armin. AU - Möller, Sören. AU - Osmanagic, Azra. AU - Sheta, Hussam. AU - Høeg Vinther, Kristina. AU - Egstrup, Kenneth. N1 - Copyright © 2015 Elsevier Inc. All rights reserved.. PY - 2015/7. Y1 - 2015/7. N2 - In patients with persistent atrial fibrillation (AF), the sinus rhythm (SR) can be restored by direct current cardioversion (DCC), although the recurrence of AF after successful DCC is common. We examined whether transesophageal echocardiography (TEE)-guided early DCC, compared with the conventional approach of DCC after 3 weeks of anticoagulation with dabigatran-etexilat, reduces the recurrence of AF. A total of 126 consecutive patients with persistent AF were randomly assigned to a TEE followed by early DCC (n = 65) or to a conventional treatment with dabigatran-etexilat for 3 weeks followed by DCC (n = 61). None of the ...
1. January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64:e1-76 2. Benjamin EJ, Wolf PA, DAgostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation. 1998;98:946-52 3. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22:983-8 4. Alegret JM, Viñolas X, Arias MA, Martínez-Rubio A, Rebollo P, Ràfols C, Martínez-Sande JL. New oral anticoagulants vs vitamin K antagonists: ...
TY - JOUR. T1 - Preoperative atrial fibrillation may not increase thromboembolic events in left ventricular assist device recipients on midterm follow-up. AU - Xia, Yu. AU - Stern, David. AU - Friedmann, Patricia. AU - Goldstein, Daniel. N1 - Funding Information: Data collection for this work was supported in whole or in part by the National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN268201100025C. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) or the National Institutes of Health. This research was also supported in part by the National Institutes of Health/National Center for Advancing Translational Science Einstein-Montefiore Clinical and Translational Science Awards Grant No. UL1TR001073. PY - 2016/7/1. Y1 - 2016/7/1. N2 - Background Atrial fibrillation (AF) is ...
BACKGROUND: In the ENGAGE AF-TIMI 48 trial, the higher-dose edoxaban (HDE) regimen had a similar incidence of ischaemic stroke compared with warfarin, whereas a higher incidence was observed with the lower-dose regimen (LDE). Amiodarone increases edoxaban plasma levels via P-glycoprotein inhibition. The current pre-specified exploratory analysis was performed to determine the effect of amiodarone on the relative efficacy and safety profile of edoxaban.. METHODS AND RESULTS: At randomization, 2492 patients (11.8%) were receiving amiodarone. The primary efficacy endpoint of stroke or systemic embolic event was significantly lower with LDE compared with warfarin in amiodarone treated patients vs. patients not on amiodarone (hazard ratio [HR] 0.60, 95% confidence intervals [CIs] 0.36-0.99 and HR 1.20, 95% CI 1.03-1.40, respectively; P interaction ,0.01). In patients randomized to HDE, no such interaction for efficacy was observed (HR 0.73, 95% CI 0.46-1.17 vs. HR 0.89, 95% CI 0.75-1.05, P ...
TY - JOUR. T1 - Clinical significance of early recurrences of atrial tachycardia after atrial fibrillation ablation. AU - Choi, Jong Il. AU - Pak, Hui Nam. AU - Park, Jae Seok. AU - Kwak, Jae Jin. AU - Nagamoto, Yasutsugu. AU - Lim, Hong Euy. AU - Park, Sang Weon. AU - Hwang, Chun. AU - Kim, Young Hoon. PY - 2010/12. Y1 - 2010/12. N2 - Early Recurrence After AF Ablation. Background: Atrial tachycardia (AT) commonly recurs within 3 months after radiofrequency catheter ablation for atrial fibrillation (AF). However, it remains unclear whether early recurrence of atrial tachycardia (ERAT) predicts late recurrence of AF or AT. Methods: Of 352 consecutive patients who underwent circumferential pulmonary vein isolation with or without linear ablation(s) for AF, 56 patients (15.9%) with ERAT were identified by retrospective analysis. ERAT was defined as early relapse of AT within a 3-month blanking period after ablation. Results: During 21.7 ± 12.5 months, the rate of late recurrence was higher in ...
TY - JOUR. T1 - Left atrial appendage closure. T2 - Six reasons why I wouldnt choose a percutaneous closure for my appendage. AU - Ferlini, Marco. AU - Rossini, Roberta. PY - 2018/1/15. Y1 - 2018/1/15. N2 - Left atrial appendage has been shown as a primary source of thrombi in patients with non-valvular atrial fibrillation (AF). Non vitamin k oral anticoagulants (NOAC) have been shown to be safe and effective in the prevention of embolic complications. Current guidelines on AF state that percutaneous left atrial appendage closure (LAAC) might be considered in patients with contraindication to long term oral anticoagulant therapy (OAC). An overview of the main trials on NOAC and LAAC is provided.. AB - Left atrial appendage has been shown as a primary source of thrombi in patients with non-valvular atrial fibrillation (AF). Non vitamin k oral anticoagulants (NOAC) have been shown to be safe and effective in the prevention of embolic complications. Current guidelines on AF state that percutaneous ...
BACKGROUND The therapeutic goals of atrial fibrillation (AF) patients are to reduce symptoms and prevent severe complications associated with AF. This study compared the efficacy of flecainide versus pilsicainide in reducing the frequency of AF and improving quality of life (QOL) in symptomatic paroxysmal AF patients without structural heart disease. METHODS The Atrial Fibrillation and Quality Of Life (AF-QOL) study was a prospective, multicenter, randomized, open-label crossover study that compared flecainide and pilsicainide as antiarrhythmic drug therapy. Patients were randomized to receive 3 months of treatment with flecainide twice daily or pilsicainide 3 times daily. Each treatment consisted of a dose-finding phase (weeks 1-4) and an efficacy phase (weeks 5-12). Forty-three patients completed the trial. The main outcome was the number of days with documented AF episodes using a patient-operated electrocardiogram. QOL questionnaires (SF-36 and AF-specific QOL scores) were also completed.
TY - JOUR. T1 - Impact of Digoxin on Mortality in Patients with Atrial Fibrillation Stratified by Heart Failure. T2 - Findings from Gulf Survey of Atrial Fibrillation Events in the Middle East. AU - Al-Zakwani, Ibrahim. AU - Panduranga, P.. AU - Zubaid, M.. AU - Sulaiman, K.. AU - Rashed, W. A.. AU - Alsheikh-Ali, A. A.. AU - Almahmeed, W.. AU - Shehab, A.. AU - Al Qudaimi, A.. AU - Asaad, N.. AU - Amin, H.. PY - 2015. Y1 - 2015. N2 - Objective: The use of digoxin in patients having atrial fibrillation (AF) with or without heart failure (HF) is not without controversy. The aim of this study was to examine the impact of digoxin therapy on mortality stratified by HF. Methods: Gulf Survey of Atrial Fibrillation Events was a prospective, multinational, observational registry of consecutive patients with AF recruited from the emergency department of 23 hospitals in 6 countries in the Middle East. Patients were recruited between October 2009 and June 2010 and followed up for 1 year after enrollment. ...
AimsDigoxin is recommended for long-term rate control in paroxysmal, persistent, and permanent atrial fibrillation (AF). While some analyses suggest an association of digoxin with a higher mortality in AF, the intrinsic nature of this association has not been examined in propensity-matched cohorts, which is the objective of the current study.Methods and resultsIn Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM), 4060 patients with paroxysmal and persistent AF were randomized to rate (n = 2027) vs. rhythm (n = 2033) control strategies. Of these, 1377 received digoxin as initial therapy and 1329 received no digoxin at baseline. Propensity scores for digoxin use were estimated for each of these 2706 patients and used to assemble a cohort of 878 pairs of patients receiving and not receiving digoxin, who were balanced on 59 baseline characteristics. Matched patients had a mean age of 70 years, 40% were women, and 11% non-white. During the 3.4 years of the mean follow-up, ...
TY - JOUR. T1 - Left atrial isolation for the treatment of atrial fibrillation due to mitral valve disease. Hemodynamic evaluation. AU - Graffigna, A.. AU - Ressia, L.. AU - Pagani, F.. AU - Minzioni, G.. AU - Vigano, M.. PY - 1993. Y1 - 1993. N2 - Ablation of atrial fibrillation secondary to mitral valve disease is frequently impossible after isolated mitral valve surgery. In order to improve sinus rhythm recovery in such patients, patients with rheumatic mitral valve disease and chronic atrial fibrillation underwent surgical electrophysiological isolation of the left atrium at the time of surgery. The left atrium is left free to fibrillate, beat or stand still, while the right atrium recovers its sinus activation and warrants a regular ventricular rate. Apart from this advantage, we tested the hypothesis that the recovery of right atrial booster function could significantly improve cardiac output. From May 1989 to July 1993 184 patients with mitral with or without other valve disease ...
A left atrial appendage closure device can be used for atrial fibrillation patients to help prevent strokes and as an alternative to blood thinners such as warfarin (Coumadin).. In atrial fibrillation, the hearts upper chambers, or atria, beat irregularly. Pooling of blood flow during atrial fibrillation in an area called the left atrial appendage can increase the risk of blood clot formations that could travel to the brain and cause a stroke.. To perform the procedure, a catheter is inserted over a guide wire through a small incision in the thigh. This catheter travels up a vein and into the right atrium then across the atrial septum and into the left atrium of the heart.. The closure device is deployed securely into the left atrial appendage and the catheter and guide wire are removed.. With the device in place, the left atrial appendage is closed off from blood flow, reducing the risk of blood clot formation and strokes.. ...
A left atrial appendage closure device can be used for atrial fibrillation patients to help prevent strokes and as an alternative to blood thinners such as warfarin (Coumadin).. In atrial fibrillation, the hearts upper chambers, or atria, beat irregularly. Pooling of blood flow during atrial fibrillation in an area called the left atrial appendage can increase the risk of blood clot formations that could travel to the brain and cause a stroke.. To perform the procedure, a catheter is inserted over a guide wire through a small incision in the thigh. This catheter travels up a vein and into the right atrium then across the atrial septum and into the left atrium of the heart.. The closure device is deployed securely into the left atrial appendage and the catheter and guide wire are removed.. With the device in place, the left atrial appendage is closed off from blood flow, reducing the risk of blood clot formation and strokes.. ...
TY - JOUR. T1 - Perceived or actual barriers to warfarin use in atrial fibrillation based on electronic medical records. AU - Rosenman, Marc B.. AU - Simon, Teresa A.. AU - Teal, Evgenia. AU - McGuire, Patricia. AU - Nisi, Daniel. AU - Jackson, Joseph D.. PY - 2012/9/1. Y1 - 2012/9/1. N2 - Compared with usual practice, clinical trials often exclude patients with relative contraindications. A study of real-world warfarin use could help inform trials of new medications that could potentially replace warfarin. The objective of this study was to describe potential barriers to warfarin use among patients with atrial fibrillation. This was a retrospective study of electronic medical records (1998-2007) from an inner-city public hospital and affiliated primary care clinics and included adults aged 18 years or more with atrial fibrillation. Exclusions included mitral or aortic valve replacement, hyperthyroidism, or no clinical encounter within 1 year after first diagnosis. Warfarin exposure was defined ...
A 72-year-old woman with a past history of untreated hypertension presents with palpitations, shortness of breath and ankle swelling for the past 72 h. Examination shows that she has atrial fibrillation with a ventricular rate of 162 bpm, a blood pressure of 146/78 mm Hg and signs of mild left ventricular failure (LVF), both clinically and on the chest x ray. ECG shows atrial fibrillation with a ventricular rate of 160 bpm and voltage criteria for left ventricular hypertrophy. You decide that ventricular rate control is the most appropriate therapy for her. You have been told recently that the chronotropic effects of digoxin are of slow onset and amiodarone runs the risk of cardioversion. You wonder therefore whether diltiazem, a calcium antagonist, may be of use ...
TY - JOUR. T1 - Amiodarone prophylaxis for atrial fibrillation after cardiac surgery. T2 - Meta-analysis of dose response and timing of initiation. AU - Buckley, Mitchell S.. AU - Nolan, Paul E.. AU - Slack, Marion K.. AU - Tisdale, James E.. AU - Hilleman, Daniel E.. AU - Copeland, Jack G.. PY - 2007/3. Y1 - 2007/3. N2 - Study Objective. To investigate a possible dose-response relationship between amiodarone and reduction in incidence of postoperative atrial fibrillation, and to determine whether pre- or postoperative initiation of amiodarone is superior. Design. Meta-analysis of randomized controlled trials. Data Source. MEDLINE and EMBASE databases and the Cochrane Central Register of Controlled Trials for English-language reports published between 1966 and December 2005. Measurements and Main Results. Of 23 identified randomized controlled trials of amiodarone prophylaxis of postoperative atrial fibrillation, 14 were included in the final analysis. These studies enrolled a total of 2864 ...
Introduction: Esophageal injury is a potential complication after catheter ablation of the posterior left atrium (LA). Therefore, we describe a new approach for complete isolation of the posterior LA including all pulmonary veins (PVs) without vertical lesions along the esophageal aspect of the posterior LA, namely Box isolation.. Methods and Results: Ninety-one patients with paroxysmal atrial fibrillation (AF) underwent Box isolation. Continuous lesions at the anterior portions of the ipsilateral PVs were initially created and then linear ablation of LA roof and bottom was performed to isolate the posterior LA. Continuous vertical lesions at the posterior portions of PVs along the esophageal aspect of the posterior LA were not created. Ablation was performed with an 8-mm-tip catheter. The endpoint was the absence of electrical activity and the inability to pace the posterior LA and all PVs in sinus rhythm. Complete isolation of the posterior LA was achieved in 82 patients (90%). Ablation ...
Anticoagulants/therapeutic use; Atrial Appendage/*physiopathology; Atrial Fibrillation/etiology/*prevention & control; Heart Catheterization; Humans; Patient Selection; *Prostheses and Implants/adverse effects; Prosthesis Design; Safety; Treatment Outcome; Warfarin/therapeutic ...
The Global Atrial Fibrillation Market is expected to reach USD 16.17 billion by 2020 growing at a CAGR of 13.2%, according to a new study by Grand View Research, Inc. Growing incidences of atrial fibrillation, strokes and brain damage due to blood clots coupled with a growing global base of geriatric population is expected to be a key driver for this market. Some of the other drivers of this market include the introduction of technological advancements in the fields of radiofrequency and microwave catheter ablation, growing demand for minimally invasive procedures and increasing prevalence of disease causing lifestyle habits such as smoking and excessive alcohol consumption. Pharmacological products for Atrial Fibrillation dominated the overall market in terms of revenue in 2013 at over 55.0%. Relatively low prices associated with these products and the use of anti-coagulants as an add-on therapy to non-pharmacological procedures, are some of the drivers of this segment.. ...
TY - JOUR. T1 - Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation. T2 - a randomised non-inferiority trial. AU - Holmes, David R.. AU - Reddy, Vivek Y.. AU - Turi, Zoltan G.. AU - Doshi, Shephal K.. AU - Sievert, Horst. AU - Buchbinder, Maurice. AU - Mullin, Christopher M.. AU - Sick, Peter. PY - 2009/8/21. Y1 - 2009/8/21. N2 - Background: In patients with non-valvular atrial fibrillation, embolic stroke is thought to be associated with left atrial appendage (LAA) thrombi. We assessed the efficacy and safety of percutaneous closure of the LAA for prevention of stroke compared with warfarin treatment in patients with atrial fibrillation. Methods: Adult patients with non-valvular atrial fibrillation were eligible for inclusion in this multicentre, randomised non-inferiority trial if they had at least one of the following: previous stroke or transient ischaemic attack, congestive heart failure, diabetes, ...
New life-saving treatments for Atrial fibrillation in clinical trial on Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II - ORBIT AF II - Phase II of the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF II) is designed to evaluate the utilization of target-specific antithrombotic agents, such as factor Xa (FXa) inhibitors and direct thrombin inhibitors, and associated outcomes.
BACKGROUND: Both segmental ostial and circumferential extraostial pulmonary vein (PV) isolation have been proven effective in the treatment of atrial fibrillation (AF). However, the recurrence of AF and PV conduction after the 2 ablation strategies h
TY - JOUR. T1 - Intracardiac echo-guided radiofrequency catheter ablation of atrial fibrillation in patients with atrial septal defect or patent foramen ovale repair. T2 - A feasibility, safety, and efficacy study. AU - Lakkireddy, Dhanunjaya. AU - Rangisetty, Umamahesh. AU - Prasad, Subramanya. AU - Verma, Atul. AU - Biria, Mazda. AU - Berenbom, Loren. AU - Pimentel, Rhea. AU - Emert, Martin. AU - Rosamond, Thomas. AU - Fahmy, Tamer. AU - Patel, Dimpi. AU - Biase, Luigi Di. AU - Schweikert, Robert. AU - Burkhardt, David. AU - Natale, Andrea. PY - 2008/11/1. Y1 - 2008/11/1. N2 - Intracardiac Echo-Guided Radiofrequency Catheter. Introduction: Patients with atrial septal defect (ASD) are at higher risk for atrial fibrillation (AF) even after repair. Transseptal access in these patients is perceived to be difficult. We describe the feasibility, safety, and efficacy of pulmonary vein antral isolation (PVAI) in these patients. Method: We prospectively compared post-ASD/patent foramen ovale (PFO) ...
Atrial fibrillation (AF) is a common complication after coronary artery bypass grafting. Atrial remodeling has been observed in AF and has been associated with the development of this arrhythmia. Because 3-hydroxy-3-methylglutaryl coenzyme A inhibitors (statins) have been demonstrated to modify remodeling, we hypothesized a protective role of statins against postoperative AF. We also hypothesized that extracellular matrix turnover and brain natriuretic peptide (BNP) might be related to such atrial remodeling. We studied 234 consecutive patients who underwent coronary artery bypass grafting (173 men; 65 +/- 9 years of age) in whom the occurrence of postoperative AF was monitored. In a subgroup of 66 patients, we measured plasma levels of matrix metalloproteinase-1 (MMP-1), its inhibitor, tissue inhibitor matrix metalloproteinase-1 (TIMP-1; as indexes of extracellular matrix remodeling), and N-terminus pro-BNP (related to left ventricular function) at baseline and at 24 hours after surgery. Of 234 ...
BACKGROUND: The anti-inflammatory or anti-arrhythmic effects of n-3 long-chain polyunsaturated fatty acids (LC-PUFA) may decrease the risk of postoperative atrial fibrillation (POAF), but interventional studies have yielded conflicting results. We examined the association between n-3 LC-PUFA and n-6 LC-PUFA in plasma phospholipids (PL) and POAF in patients undergoing coronary artery bypass grafting (CABG). METHODS: A total of 125 patients undergoing CABG were enrolled in the study. The levels of fatty acids in PL were measured preoperatively and on the third postoperative day. The endpoint was defined as POAF lasting ≥5 min. The incidence of POAF was compared between quartiles of the level of each fatty acid in plasma PL by univariate and multivariable analysis. RESULTS: The incidence of POAF was 49·6%. By univariate analysis, the incidence of POAF increased significantly with each higher quartile of pre- and postoperative docosahexaenoic acid (DHA) and diminished significantly with each ...
Left atrial appendage electrical isolation in addition to standard ablation appears to have a substantial incremental benefit to achieve freedom from ALL atrial arrhythmias in patients with persistent AF and LSPAF without increasing acute procedural complications and without raising the risk of isch …
Oral anticoagulant therapy is the mainstay of stroke prevention in patients with atrial fibrillation; it is highly effective at reducing stroke risk, but its use can be limited by increased risk of bleeding. As new oral anticoagulants are available, barriers to optimal use of oral anticoagulation therapy warrant consideration by healthcare professionals and administrators who are seeking to optimize the quality of care for patients with atrial fibrillation.
The need for this trial arises out of 1) the rapidly increasing number of pts , 60 years of age with AF accompanied by symptoms and morbidity, 2) the failure of anti-arrhythmic drug therapy to maintain sinus rhythm and reduce mortality, 3) the rapidly increasing application of radio-frequency catheter ablation without appropriate evidence-based validation, and 4) the expanding impact of AF on health care costs.. This study will randomize up to 2200 patients to a strategy of catheter ablation versus pharmacologic therapy with rate or rhythm control drugs. Each pt will have 1) characteristics similar to AFFIRM pts (≥65 yo or ,65 with ,1 risk factor for stroke, 2) Documented AF warranting treatment, and 3) Eligibility for both catheter ablation and ≥2 anti-arrhythmic or ≥2 rate control drugs. Pts will be followed every 6 months for an average of approximately 5 years and will undergo repeat trans-telephonic monitor, Holter monitor, and CT/MR studies to assess the impact of treatment.. The ...
Atrial fibrillation is a common heart rhythm abnormality (arrhythmia) in dogs. This arrhythmia affects all dog breeds and frequently coexists with heart failure causing worsening of disease and high mortality. Atrial fibrillation may be managed by administering drugs to slow heart rate or by restoring normal rhythm (cardioversion). Dr. Bright will evaluate dogs with naturally occurring atrial fibrillation and heart failure for their responsiveness to two drugs -- amidodarone, an antiarrhythmic agent, and ranolazine, a drug used in humans with coronary heart disease. She will determine whether ranolazine given with amiodarone prolongs normal rhythm compared to amiodarone alone and whether ranolazine also improves heart function. Results will validate combined ranolazine/amiodarone administration as an improved new treatment for atrial fibrillation in dogs with heart failure, extending their quality of life. Project Summary Atrial fibrillation (AF) is a common heart rhythm abnormality (arrhythmia) that
Ferro D and colleagues from Sapienza University of Rome, Rome, Italy have come up with evidence [CIRCEP.111.968248 Published online before print February 23, 2012, doi: 10.1161/?CIRCEP.111.968248] that low serum vitamin E levels are associated with recurrence of atrial fibrillation (AF) after cardioversion. They hypothesise that vitamin E being an antioxidant, low vitamin E levels would correlate with oxidative stress which could have a role in recurrence of atrial fibrillation after cardioversion. The study involved one hundred and forty four patients who had undergone electrical cardioversion with biphasic shocks for non valvar persistent atrial fibrillation. During the three month follow up ninety four patients were in sinus rhythm while fifty had recurrence of atrial fibrillation. Serum vitamin E levels were lower in patients with recurrence of atrial fibrillation (p,0.001). Higher left atrial diameter, urinary isoprostanes, high sensitivity C reactive protein (hsCRP) and sNOX2-dp (soluble ...
Atrial fibrillation is the commonest cardiac arrhythmia. While a number of established drug therapies are often successful in achieving satisfactory control, more recently radiofrequency catheter ablation has emerged as an effective therapy for patients with paroxysmal AF. However, the place of catheter ablation remains unclear with limited data comparing ablation with antiarrhythmic drug therapy as first-line treatment in patients.. In the MANTRA-PAF trial 294 patients (mean age 55) with new onset paroxysmal atrial fibrillation and no history of antiarrhythmic drug use were randomly assigned to an initial strategy of either catheter ablation (146 patients) or therapy with class IC or class III antiarrhythmic agents (148 patients). Follow-up was by 7-day Holter-monitoring at 3, 6, 12, 18, and 24 months. The primary end points were the cumulative and per-visit burden of atrial fibrillation (i.e., percentage of time in atrial fibrillation). During follow-up there was no significant difference ...
Self monitoring is safe and has various studies to prove this. Patients who self monitor have a better life expectancy. Discuss dealing with health professionals when patient knows more about the illness - Patients need to be empowered about there conditions and to give them the confidence to speak with clinicians about what is happening to them. Discuss self monitoring if they wish (not always suitable for APS patients). The NICE Quality Standards for Atrial Fibrillation Statement 6 (developmental) sates Adults with atrial fibrillation on long‑term vitamin K antagonist therapy are supported to self‑manage with a coagulometer. This means that every anticoagulation service in the UK should provide this opportunity to patients. Professor Beverley Hunt Biography: Professor Beverley Hunt is Professor of Thrombosis & Haemostasis at Kings College London and is a Consultant in the Departments of Haematology, Pathology and Rheumatology at Guys & St Thomas NHS Foundation Trust.. She has a ...
Incidence of Direct Oral Anticoagulant use in patients with non-valvular atrial fibrillation and characteristics of users in six European countries (2008-2015): A cross-national drug utilization ...
A study comparing atrial fibrillation patients who do yoga with patients who do not, shows it may improve quality of life, lower heart rate and lower blood pressure.
Denmark MedicalResearch.com: What is the background for this study? What are the main findings?. Response: Atrial fibrillation increases a persons risk of ischemic strokes up to 5-fold. Oral anticoagulation therapy lowers this risk effectively (,60%) and is therefore recommended for patients with atrial fibrillation and at least 1-2 other risk factors for stroke.. Our study show, that oral anticoagulation therapy is still underused in patients with atrial fibrillation - even after a stroke event. In stroke survivors with atrial fibrillation, oral anticoagulation therapy were associated with better outcomes than no oral anticoagulation therapy. MedicalResearch.com: What should readers take away from your report?. Response: Oral anticoagulation therapy is effective (and safe) as secondary stroke prophylaxis in patients with atrial fibrillation.. MedicalResearch.com: What recommendations do you have for future research as a result of this work? Response: Treatment rates with oral anticoagulation ...
TY - JOUR. T1 - Primary prevention of atrial fibrillation with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with end-stage renal disease undergoing dialysis. AU - Lin, Ting Tse. AU - Yang, Yao Hsu. AU - Liao, Min Tsun. AU - Tsai, Chia Ti. AU - Hwang, Juey J.. AU - Chiang, Fu Tien. AU - Chen, Pau Chung. AU - Lin, Jiunn Lee. AU - Lin, Lian Yu. PY - 2015/8/4. Y1 - 2015/8/4. N2 - Current evidence suggests that angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) reduce the incidence of new atrial fibrillation (AF) in a variety of clinical conditions, including the treatment of left ventricular dysfunction or hypertension. Here we assessed whether ACEIs and ARBs could decrease incidence of new-onset AF in patients with end-stage renal disease (ESRD). We identified patients from the Registry for Catastrophic Illness, a nation-wide database encompassing almost all of the patients receiving dialysis therapy in Taiwan from ...
BACKGROUND: Dronedarone is a new antiarrhythmic drug that is being developed for the treatment of patients with atrial fibrillation. METHODS: We conducted a multicenter trial to evaluate the use of dronedarone in 4628 patients with atrial fibrillation who had additional risk factors for death. Patients were randomly assigned to receive dronedarone, 400 mg twice a day, or placebo. The primary outcome was the first hospitalization due to cardiovascular events or death. Secondary outcomes were death from any cause, death from cardiovascular causes, and hospitalization due to cardiovascular events. RESULTS: The mean follow-up period was 21+/-5 months, with the study drug discontinued prematurely in 696 of the 2301 patients (30.2%) receiving dronedarone and in 716 of the 2327 patients (30.8%) receiving placebo, mostly because of adverse events. The primary outcome occurred in 734 patients (31.9%) in the dronedarone group and in 917 patients (39.4%) in the placebo group, with a hazard ratio for ...
Good evidence exists that adjusted-dose warfarin reduces the risk for stroke in patients with nonvalvular atrial fibrillation (1). However, because regular monitoring of the INR is required and because of the risk for hemorrhage, a safer alternative is desirable. Aspirin is safer and more convenient but less effective than warfarin (2, 3). This study was restricted to patients who had at least 1 risk factor for stroke in addition to atrial fibrillation. In these patients, the effects of low-intensity, fixed-dose warfarin plus aspirin were disappointing; the risk for stroke increased, and the risk for major hemorrhage was not reduced. Patients who are at high risk for stroke stand to gain more from treatment than patients at low risk for stroke, and the SPAF III study confirms the benefit of adjusted-dose warfarin for these patients. Increasing evidence supports a target range of 2.0 to 3.0 for the INR. The risk for stroke rises steeply if the INR is , 2, and the risk for hemorrhage rises if it ...
TY - GEN. T1 - How Accurately Can We Detect Atrial Fibrillation Using Photoplethysmography Data Measured in Daily Life?. AU - Eerikäinen, Linda M.. AU - Bonomi, Alberto G.. AU - Schipper, Fons. AU - Dekker, Lukas. AU - Vullings, Rik. AU - De Morree, Helma M.. AU - Aarts, Ronald M.. PY - 2019/9. Y1 - 2019/9. N2 - Photoplethysmography (PPG) is an unobtrusive measurement modality recently explored for the detection of atrial fibrillation (AF). When used in wrist-worn applications, PPG-monitoring can be used for long-term monitoring in daily life, which is beneficial when aiming to detect AF. The objective of this study was to investigate whether the performance of an AF detection model trained and tested on short measurements is generalizable to measurements in daily life. PPG, accelerometer, as well as reference ECG data were measured from 32 subjects (13 continuous AF, 19 no AF) in 24-hour monitoring in daily life. An AF detection model combining inter-pulse interval features was trained to ...
BACKGROUND: Warfarin reduces the risk of stroke in patients with atrial fibrillation but increases the risk of hemorrhage and is difficult to use. Dabigatran is a new oral direct thrombin inhibitor.. METHODS: In this noninferiority trial, we randomly assigned 18,113 patients who had atrial fibrillation and a risk of stroke to receive, in a blinded fashion, fixed doses of dabigatran--110 mg or 150 mg twice daily--or, in an unblinded fashion, adjusted-dose warfarin. The median duration of the follow-up period was 2.0 years. The primary outcome was stroke or systemic embolism.. RESULTS: Rates of the primary outcome were 1.69% per year in the warfarin group, as compared with 1.53% per year in the group that received 110 mg of dabigatran (relative risk with dabigatran, 0.91; 95% confidence interval [CI], 0.74 to 1.11; P,0.001 for noninferiority) and 1.11% per year in the group that received 150 mg of dabigatran (relative risk, 0.66; 95% CI, 0.53 to 0.82; P,0.001 for superiority). The rate of major ...
BACKGROUND The success rate after cryoballoon ablation (CB-A) performed for paroxysmal atrial fibrillation (PAF) might be underestimated by traditional noninvasive monitoring techniques. The purpose of this study was to evaluate the mid-term outcome o
The recent introduction of direct-current external electric shock for the restoration of a normal sinus mechanism in patients with atrial fibrillation has reopened the question of the desirability of restoring a normal sinus pacemaker. To determine whether restoration of a sinus rhythm is hemodynamically beneficial to some or all patients, we have measured the cardiac output in a group of 47 patients with atrial fibrillation in whom an attempt at conversion was about to be made. The cardiac output determination was repeated if restoration of a normal sinus rhythm was accomplished.. All patients were given digitalis in doses sufficient to ...
... in atrial myocytes, which aids in suppressing atrial fibrillation. AF and TdP may be induced with L-type calcium channel ... "AZD1305 Exerts Atrial Predominant Electrophysiological Actions and is Effective in Suppressing Atrial Fibrillation and ... Atrial fibrillation (AF) is a form of cardiac arrhythmia that arises with disorganized and rapid action upotentials conducted ... specifically atrial fibrillation and flutter. In vitro studies have shown that this combined-ion channel blocker inhibits ...
Atrial fibrillation - (AF or A-fib) is an abnormal heart rhythm characterized by rapid and irregular beating of the atria. ... Munger, TM; Wu, LQ; Shen, WK (January 2014). "Atrial fibrillation". Journal of Biomedical Research. 28 (1): 1-17. doi:10.7555/ ... Zoni-Berisso, M; Lercari, F; Carazza, T; Domenicucci, S (2014). "Epidemiology of atrial fibrillation: European perspective". ...
Atrial fibrillation". In Kaski, Juan Carlos; Kjeldsen, Keld Per (eds.). The ESC Handbook on Cardiovascular Pharmacotherapy. ... 2020 ESC guidelines on atrial fibrillation recommend assessment of bleeding risk in AF using the HAS-BLED bleeding risk schema ... 2012). "2012 focused update of the ESC Guidelines for the management of atrial fibrillation: An update of the 2010 ESC ... Lip, Gregory Y.H. (2011). "Implications of the CHA2DS2-VASc and HAS-BLED Scores for Thromboprophylaxis in Atrial Fibrillation ...
TF Atrial fibrillation; 608583; GJA5 Atrial fibrillation, familial, 3; 607554; KCNQ1 Atrial fibrillation, familial, 4; 611493; ... KCNE2 Atrial fibrillation, familial, 6; 612201; NPPA Atrial fibrillation, familial, 7; 612240; KCNA5 Atrial septal defect 4; ... 611363; TBX20 Atrial septal defect 5; 612794; ACTC1 Atrial septal defect 6; 613087; TLL1 Atrial septal defect with ... TEK Ventricular fibrillation, familial, 1; 603829; SCN5A Ventricular fibrillation, paroxysmal familial, 2; 612956; DPP6 ...
Examples: Atrial fibrillation; Infection. 1. Implantation technique. Example: Inflow cannula malposition. 2. Inadequate ...
Accredited Atrial Fibrillation; Accredited Chest Pain Center with Primary PCI; Accredited by the American Association of ...
Journal of Atrial Fibrillation. 7 (2): 1035. doi:10.4022/jafib.1035 (inactive 17 January 2021). PMC 5135249. PMID 27957092.CS1 ...
He had his first heart attack in 1901, and recorded in himself the atrial fibrillation that accompanied this episode. By 1907 ... McMichael J. (July 1981). "Sir James Mackenzie and atrial fibrillation-a new perspective". J R Coll Gen Pract. 31 (228): 402-6 ... Fazekas, T; Liszkai, G; Bielik, H; Lüderitz, B (2003). "[History of atrial fibrillation]". Zeitschrift für Kardiologie. 92 (2 ... Fazekas, Tamás; Liszkai, Gizella (2002). "[History of atrial fibrillation]". Orvosi Hetilap. 143 (6) (published 10 February ...
Lip GY, Watson RD, Singh SP (December 1995). "ABC of atrial fibrillation. Drugs for atrial fibrillation". BMJ. 311 (7020): 1631 ...
... atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been ... It was also approved for the control of ventricular response rate for patients with atrial fibrillation. American College of ... Hollman, A. (April 1996). "Drugs for atrial fibrillation. Digoxin comes from Digitalis lanata". BMJ (Clinical Research Ed.). ... and as such is used in re-entrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The ...
"Journal of Atrial Fibrillation. 7 (2): 1035. doi:10.4022/jafib.1035 (inactive 2018-09-20). PMC 5135249. PMID 27957092.. ...
Sobieraj-Teague, M.; O'donnell, M.; Eikelboom, J. (2009). "New Anticoagulants for Atrial Fibrillation". Seminars in Thrombosis ... "Oral factor Xa inhibitors for the prevention of stroke in atrial fibrillation". Current Opinion in Cardiology. 25 (4): 312-20. ... trials for prevention of embolism after knee surgery and for prevention of stroke following non-valvular atrial fibrillation. ...
"Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators". The New England ... in patients with paroxysmal atrial fibrillation and pacemakers with atrial fibrillation data logging capabilities. Heart Rhythm ... A decrease in heart rate reduces the risk of atrial fibrillation. Preliminary trials of budiodarone have administered the drug ... Evidence has shown that 400-600 mg bid doses were associated with the highest reduction in atrial fibrillation burden (54.4% ...
Sullivan ML, Martinez CM, Gallagher EJ (1999). "Atrial fibrillation and anabolic steroids". The Journal of Emergency Medicine. ...
CS1 maint: discouraged parameter (link) "Prevention of Stroke in Atrial Fibrillation - Elimination of the Left Atrial Appendage ... He is the creator of the Wolf Mini Maze, a procedure used to correct atrial fibrillation (AF). Wolf previously hosted a weekly ... In 2015, Wolf relocated the Atrial Fibrillation Center to Houston, Texas where he was featured on Fox 26 News. He served as ... Wolf serves on the Global Medical Advisory Board of StopAfib.org, a patient-to-patient resource to control atrial fibrillation ...
Abbott, Louise (December 2012). "Atrial Fibrillation - information, symptoms and treatment". Bupa. Port, Carol Mattson (2005). ... An ectopic pacemaker located in the atria is known as an atrial pacemaker and can cause the atrial contraction to be faster. An ... and role of segmental superior vena cava isolation in the treatment of atrial fibrillation". Journal of Electrocardiology. 40 ( ... "Disturbances in Atrial Rhythm and Conduction Following the Surgical Creation of an Atrial Septal Defect by the Blalock-Hanlon ...
Lau DH, Nattel S, Kalman JM, Sanders P (August 2017). "Modifiable Risk Factors and Atrial Fibrillation". Circulation (Review). ... atrial fibrillation, cancers and pulmonary embolism. Hypertension is also a risk factor for cognitive impairment and dementia. ... atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. High blood pressure is ...
History of atrial fibrillation? Yes (+1) Coronary artery disease? Yes (+1) eGFR < 60 ml/min/1.73*m2? Yes (+1) Urine albumin-to- ... in individuals with atrial fibrillation. Patients were randomized to one of three treatment groups: High Dose Regimen, Low Dose ...
"Ranolazine Reduces The Late Recurrences Of Atrial Fibrillation. An Exploratory Analysis Of The Raffaello Study". Treatment of ... Pharmacological-atrial Fibrillation. 130. November 2014. Retrieved 2016-11-07. "MEN1112, a Novel Humanized De-Fucosylated ...
Aghenta A; Osowo, A; Thomas, J (May 2008). "Symptomatic atrial fibrillation with infectious mononucleosis". Canadian Family ...
... atrial fibrillation affects about 2% to 3% of the population. Atrial fibrillation and atrial flutter resulted in 112,000 deaths ... Supraventricular tachycardias include atrial fibrillation, atrial flutter, and paroxysmal supraventricular tachycardia. ... Zoni-Berisso, M; Lercari, F; Carazza, T; Domenicucci, S (2014). "Epidemiology of atrial fibrillation: European perspective". ... and arrhythmias such as atrial fibrillation, are common and are a major cause of mortality in elderly people. Vascular ...
"Clinical Management of Atrial Fibrillation" (2015); and "Cardiac Arrhythmias, Pacing and Sudden Death" (2017). His most-cited ... "Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutter". New England Journal of Medicine. 357 (10): 987- ...
Turpie, AG (Jan 2008). "New oral anticoagulants in atrial fibrillation". European Heart Journal. 29 (2): 155-65. doi:10.1093/ ... prevent stroke and embolism in people with non-valvular atrial fibrillation (AF) who have other risk factors, and prevent blood ... and prevent stroke and embolism in people with atrial fibrillation (AF). Direct factor Xa inhibitors include rivaroxaban, ...
... is associated with altered predisposition to lone atrial fibrillation and postoperative atrial fibrillation. Atrial KCNE1 ... Han HG, Wang HS, Yin Z, Jiang H, Fang M, Han J (20 October 2014). "KCNE1 112G>a polymorphism and atrial fibrillation risk: a ... "Atrial fibrillation in KCNE1-null mice". Circulation Research. 97 (1): 62-9. doi:10.1161/01.RES.0000173047.42236.88. PMID ... gain-of-function KCNE1 mutations are associated with early-onset atrial fibrillation. A common KCNE1 polymorphism, S38G, ...
Fibrillation can affect the atrium (atrial fibrillation) or the ventricle (ventricular fibrillation): ventricular fibrillation ... atrial fibrillation affects about 2% to 3% of the population. Atrial fibrillation and atrial flutter resulted in 112,000 deaths ... Atrial fibrillation affects the upper chambers of the heart, known as the atria. Atrial fibrillation may be due to serious ... Sinus bradycardia Premature atrial contractions (PACs) Wandering atrial pacemaker Atrial tachycardia Multifocal atrial ...
1975; 231: 734-5. Micturition syncope, hypokalemia, and atrial fibrillation. Kounis NG, Kenmure AC. JAMA 1976; 236: 954 " ...
Atrial origin: Ectopic (unifocal) atrial tachycardia (EAT) Multifocal atrial tachycardia (MAT) Atrial fibrillation with rapid ... There are four main types: atrial fibrillation, paroxysmal supraventricular tachycardia (PSVT), atrial flutter, and Wolff- ... atrial fibrillation. Atrial flutter is also not necessarily a tachycardia unless the AV node permits a ventricular response ... For atrial fibrillation calcium channel blockers or beta blockers may be used. Long term some people benefit from blood ...
... which was recognized as the first cure for atrial fibrillation. From 1990 to 1997 he was Evarts A. Graham Professor of Surgery ... Global Atrial Fibrillation Alliance 2014 - The Burakovsky Award, Bakoulev National Cardiovascular Institute, Moscow, Russia ... "The surgical treatment of atrial fibrillation. III. Development of a definitive surgical procedure". J Thorac Cardiovasc Surg. ... Cox Fellowship in Surgery for Atrial Fibrillation", American Association for Thoracic Surgery Foundation 2016 - Scientific ...
In 2007 MMRI researchers studied atrial-selective sodium channel block as a strategy to manage atrial fibrillation. They later ... as an atrial selective sodium channel blocker capable of suppressing atrial fibrillation in experimental models. In 2012 they ... Atrial-selective inhibition of sodium channel current by Wenxin Keli is effective in suppressing atrial fibrillation. Heart ... A computer model of atrial fibrillation. Am Heart J 1964;67:200-220. Sicouri S, Antzelevitch C. A subpopulation of cells with ...
Atrial fibrillation is usually present in patients with tricuspid regurgitation Patients with aortic stenosis can have chest X- ... Patients also commonly have atrial fibrillation. Patients may have a laterally displaced apex beat, often with heave In acute ... ECG can show left atrial enlargement, due to increased pressures in the left atrium. Echocardiography is helpful in determining ... Anticoagulation is recommended for patients that have mitral stenosis in the setting of atrial fibrilliation or a previous ...
A type of abnormal heart rhythm called atrial fibrillation ("A-fib"). *Recent surgery (after surgery, the body's blood clotting ...
... as in atrial fibrillation. The equivalent atrial pacing mode is AAI or AAIR which is the mode of choice when atrioventricular ... Right atrial and right ventricular leads as visualized under x-ray during a pacemaker implant procedure. The atrial lead is the ... An ECG in a person with an atrial pacemaker. Note the circle around one of the sharp electrical spike in the position where one ... Often, for patients in normal sinus rhythm, there is also a lead in the right atrium to facilitate synchrony with the atrial ...
Zoni-Berisso, M; Lercari, F; Carazza, T; Domenicucci, S (2014). "Epidemiology of atrial fibrillation: European perspective". ... ଆଟ୍ରିଆଲ ଫ୍ଲଟର atrial flutter, ଓ ଉଲ୍ଫ-ପାର୍କିନସନ-ହ୍ୱାଇଟ ସିଣ୍ଡ୍ରୋମ (Wolff-Parkinson-White syndrome) ।[୧] ଦୃତ ହୃତ୍‌ସ୍ପନ୍ଦନ ( ...
Adrenergic storm Alcohol Amphetamine Anaemia Antiarrhythmic agents Anxiety Atrial fibrillation Atrial flutter Atrial ... vena cava Atrial fibrillation Atrial flutter AV nodal reentrant tachycardia Accessory pathway mediated tachycardia Atrial ... Atrial fibrillation is one of the most common cardiac arrhythmias. In general, it is an irregular, narrow complex rhythm. ... Depending on the patient's health and other variables such as medications taken for rate control, atrial fibrillation may cause ...
Atrial fibrillation[edit]. Atrial fibrillation is one of the most common cardiac arrhythmias. In general, it is an irregular, ... Depending on the patient's health and other variables such as medications taken for rate control, atrial fibrillation may cause ... new onset atrial fibrillation tends to present with rates between 100 and 150 beats per minute.[citation needed] ... Sinus tachycardia, which originates from the sino-atrial (SA) node, near the base of the superior vena cava ...
"Complex" ablations include ablation for arrhythmias such as multifocal atrial tachycardia, atrial fibrillation, and ventricular ... atrial flutter. These procedures are usually performed using intracardiac catheters (as are used during an electrophysiology ...
"Atrial fibrillation and apoplexy--risks and prevention". Københavns praktiserende laegers laboratorium, AFASAK 2 Center; ... Fibrilasi atrial[sunting , sunting sumber]. Fibrilasi atrial merupakan indikasi terjadinya kardioembolisme, sedangkan ... atrial fibrillation, migraine dengan aura, dan thrombophilia (cenderung thrombosis). Dari semua faktor-faktor tersebut yang ... PFO merupakan salah satu bentuk sindrom platipnea-ortodeoksia dengan peningkatan ortostatik di area defisiensi atrial septal.[ ...
Fibrillation can affect the atrium (atrial fibrillation) or the ventricle (ventricular fibrillation); ventricular fibrillation ... Atrial fibrillation is often due to serious underlying medical conditions, and should be evaluated by a physician. It is not ... Atrial fibrillation can also be treated through a procedure, e.g. pulmonary vein isolation. This is performed by a cardiologist ... Ventricular fibrillation occurs in the ventricles (lower chambers) of the heart; it is always a medical emergency. If left ...
Some research has shown increased incidences of atrial fibrillation to be associated but this relationship is not yet clearly ...
In people with atrial fibrillation, conduction defects, or heart block, quinine can cause heart arrhythmias, and should be ...
... and with higher rates of atrial fibrillation in elderly patients.[citation needed] ...
Clinical guideline 36: Atrial fibrillation. London, June 2006. *↑ 9.0 9.1 Hunt BJ (March 2008). "Awareness and politics of ...
Atrial fibrillation *Familial. *Ventricular fibrillation. Pacemaker. *Ectopic pacemaker / Ectopic beat. *Multifocal atrial ...
Valvular atrial fibrillation refers to atrial fibrillation attributable to moderate to severe mitral valve stenosis or atrial ... Northwestern Surgery for Atrial Fibrillation. Atrial Fibrillation Surgery Archived 19 April 2012 at the Wayback Machine ... There are multiple theories about the cause of atrial fibrillation. An important theory is that, in atrial fibrillation, the ... Because the diagnosis of atrial fibrillation requires measurement of the electrical activity of the heart, atrial fibrillation ...
... atrial fibrillation, or guttural pouch mycoses. Effects on performance[edit]. EIPH reduces a horse's racing performance. Severe ... pulmonary infection or atrial fibrillation, inflammation, longer distances, longer duration of exercise, hard surfaces, ...
The negative chronotropic effects of CCBs make them a commonly used class of agents in individuals with atrial fibrillation or ... especially from atrial fibrillation), to prevent peripheral and cerebral vasospasm, and to reduce chest pain caused by angina ...
... blood can lead to pleural and pericardial effusions and contribute to the triggering of postoperative atrial fibrillation in ...
Atrial fibrillation, June 2006 *↑ Hunt BJ (March 2008)։ «Awareness and politics of venous thromboembolism in the United kingdom ... Clotting state after cardioversion of atrial fibrillation: a haemostasis index could detect the relationship with the ...
"Effect of atrial fibrillation on the dynamics of mitral annular area". The Journal of Heart Valve Disease. 12 (1): 31-7. PMID ... Left atrial contraction (left atrial systole) (during left ventricular diastole) causes added blood to flow across the mitral ... pulmonary veins) → left atrium (atrial appendage) → mitral valve → left ventricle → aortic valve (aortic sinus) → (aorta and ... venae cavae, coronary sinus) → right atrium (atrial appendage, fossa ovalis, limbus of fossa ovalis, crista terminalis, valve ...
... but he was suddenly grounded for an atrial fibrillation.[45] Carpenter was assigned to replace him instead of Slayton's backup ...
... results from the National Registry of Atrial Fibrillation 2". Arch. Intern. Med. 166 (2): 241-6. doi:10.1001/archinte.166.2.241 ...
... which can also result in atrial fibrillation, poor heartbeat and lack of energy.[44] ...
Zoni-Berisso, M; Lercari, F; Carazza, T; Domenicucci, S. Epidemiology of atrial fibrillation: European perspective.. Clinical ... 心室顫動(英語簡稱V-Fib或VF),是其中一種心律不整的表徵。( Ventricular fibrillation (VF) showing disorganized electrical activity
... dimensions and relaxation in patients with atrial fibrillation". European Heart Journal. Suppl A: 149-56. PMID 7274225.. ... Left atrial dimension. LA. Range 24 - 40 mm[16] Fractional shortening (FS) is the fraction of any diastolic dimension that is ... pulmonary veins) → left atrium (atrial appendage) → mitral valve → left ventricle → aortic valve (aortic sinus) → (aorta and ... venae cavae, coronary sinus) → right atrium (atrial appendage, fossa ovalis, limbus of fossa ovalis, crista terminalis, valve ...
"Anticoagulation in atrial fibrillation: NOAC's the word". Deutsches Ärzteblatt International. 110 (31-32): 523-4. doi:10.3238/ ... dabigatran etexilate was approved by the FDA to treat atrial fibrillation. Relevance to dental treatmentsEdit. As in any ... results from the National Registry of Atrial Fibrillation 2". Archives of Internal Medicine. 166 (2): 241-6. doi:10.1001/ ... "Antithrombotic therapy in patients with atrial fibrillation and coronary artery disease". Avicenna Journal of Medicine. 9 (4): ...
Fibrilasi atrial (bahasa Inggris: atrial fibrillation, A-fib, AF) adalah simtoma ritme denyut abnormal yang terjadi di jantung ... "The mechanisms of atrial fibrillation in hyperthyroidism". Department of Hypertension, Department of Nephrology, Hypertension ... "New insights into the mechanisms and management of atrial fibrillation". Department of Medicine, Université de Montréal, ... Diperoleh dari "https://id.wikipedia.org/w/index.php?title=Fibrilasi_atrial&oldid=11998428" ...
It is used in recurrent atrial flutter (Afl), atrial fibrillation (AF), supraventricular tachycardia (SVT), atrial tachycardia ... Ablation is now the standard treatment for SVT and typical atrial flutter and the technique can also be used in AF, either to ... In 2004, former British prime minister Tony Blair underwent radiofrequency catheter ablation for recurrent atrial flutter. In ... Multifocal Atrial Tachycardia (MAT) and some types of ventricular arrhythmia. The energy-emitting probe (electrode) is at the ...
Thus, common clinical indications for warfarin use are atrial fibrillation, the presence of artificial heart valves, deep ... Anticoagulation and Risk Factors in Atrial Fibrillation) Study". Journal of the American College of Cardiology. 58 (4): 395-401 ... results from the National Registry of Atrial Fibrillation 2". Archives of Internal Medicine. 166 (2): 241-6. doi:10.1001/ ... "2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for ...
"Fatal ventricular fibrillation following verapamil in Wolff-Parkinson-White syndrome with atrial fibrillation". Annals of ... Atrial septostomy is a surgical procedure that creates a communication between the right and left atria. It relieves pressure ... show a murmur of tricuspid insufficiency and ventricular and atrial gallops. ...
Heart Failure in Atrial Fibrillation. (10-year risk). (based on Schnabel RB, Rienstra M, Sullivan LM, Sun JX, Moser CB, Levy D ... Risk assessment for incident heart failure in individuals with atrial fibrillation. Eur J Heart Fail. 2013;15:843-849. PMID ... Participants with manifest atrial fibrillation free of heart failure at baseline, aged 39 to 96 years ... Atrial Fibrillation *Framingham Heart Study AF score. (10-year risk). *Heart Failure in Atrial Fibrillation (10-year risk) ...
Valvular atrial fibrillation refers to atrial fibrillation attributable to moderate to severe mitral valve stenosis or atrial ... Northwestern Surgery for Atrial Fibrillation. Atrial Fibrillation Surgery Archived 19 April 2012 at the Wayback Machine ... There are multiple theories about the cause of atrial fibrillation. An important theory is that, in atrial fibrillation, the ... Because the diagnosis of atrial fibrillation requires measurement of the electrical activity of the heart, atrial fibrillation ...
Learn about atrial fibrillation, often called AFib or AF, the most common type of treated heart arrhythmia. ... What is atrial fibrillation?. Atrial fibrillation, often called AFib or AF, is the most common type of treated heart arrhythmia ... Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22(8):983-8. ... 2019). Complications from Atrial Fibrillation. Accessed May 9, 2019.. *Centers for Disease Control and Prevention, National ...
Atrial fibrillation (AF or AFib) is the most common type of arrhythmia (irregular heartbeat). Read about symptoms and treatment ... Atrial fibrillation - discharge (Medical Encyclopedia) Also in Spanish * Atrial fibrillation or flutter (Medical Encyclopedia) ... Atrial Fibrillation Medications (American Heart Association) * Cardioversion (National Heart, Lung, and Blood Institute) Also ... Atrial Fibrillation and Stroke (National Institute of Neurological Disorders and Stroke) * Device Interventions for Stroke ...
Review the various types of antiarrhythmic agents used in the treatment of atrial fibrillation in this primer. How should the ... Appropriate Treatment of Atrial Fibrillation: Which Dose for Which Patient? 0.25 CME / ABIM MOC Credits ... Atrial fibrillation (AF) is one of the most common forms of cardiac disturbances, diagnosed in an estimated 2.7 million to 6.1 ... Atrial fibrillation is one of the most common forms of cardiac disturbances, diagnosed in an estimated 2.7 million to 6.1 ...
Familial atrial fibrillation is an inherited abnormality of the hearts normal rhythm. Explore symptoms, inheritance, genetics ... Familial atrial fibrillation is an inherited abnormality of the hearts normal rhythm. Atrial fibrillation is characterized by ... Atrial fibrillation also increases the risk of stroke and sudden death. Complications of atrial fibrillation can occur at any ... medlineplus.gov/genetics/condition/familial-atrial-fibrillation/ Familial atrial fibrillation. ...
... To Ablate or Not to Ablate. Avishag Laish-Farkash, M.D., Ph.D.; Vladimir Khalameizer, M.D ... Atrial Fibrillation in Patients With Renal Impairment: How to Manage 0.5 CME / ABIM MOC Credits ... The reality that atrial fibrillation (AF) is the most frequently encountered arrhythmia in clinical practice, and that the ... The 2011 ACCF/AHA/HRS Focused Update on the Management of Patients with Atrial Fibrillation mentioned that the average age of ...
Fibrilación atrial, Fibrilacion atrial (es); Fibrilação atrial, Fibrilhação auricular (pt); Fibrillation Auriculaire (fr); ... Media in category "Atrial fibrillation". The following 7 files are in this category, out of 7 total. ... Atrial fibrillation video.webm 7 min 31 s, 1,812 × 1,018; 36.86 MB. ... atrial fibrillation (en); رجفان أذيني (ar); Κολπική μαρμαρυγή (el); 심방세동 (ko) alterazione del ritmo cardiaco (aritmia) ad ...
How do you treat atrial fibrillation? Learn about medicines, procedures, and other treatments to get your heart back into a ... Articles OnAtrial Fibrillation Treatments. Atrial Fibrillation Treatments Atrial Fibrillation Treatments - What Are the ... Cleveland Clinic: "Atrial Fibrillation (AFib).". National Heart, Lung, and Blood Institute: "How Is Atrial Fibrillation Treated ... "Atrial Fibrillation Medications," "Non-surgical Procedures for Atrial Fibrillation (AFib or AF)," "Surgical Procedures for ...
Learn about the role of inflammation in atrial fibrillation, AF in athletes, nuances of rate control, progress in ablation, and ... atrial fibrillation in patients with type 2 diabetes mellitus. The combination of atrial fibrillation and diabetes confers an ... A patient with atrial fibrillation with a CHADS2 score of 3 is taking warfarin. She hasnt had a prior episode of ... Atrial fibrillation (AF) has been linked with an increased risk for cognitive impairment and dementia in numerous studies over ...
Treatment for atrial fibrillation (AF) depends on how severe or frequent the symptoms are and whether you already have heart ... Treatment for atrial fibrillation (AF) depends on how severe or frequent the symptoms are and whether you already have heart ... Who Needs Treatment for Atrial Fibrillation?. People with no symptoms and no related heart problems may not need treatment. AF ... Atrial Fibrillation (AF). *Atrial Fibrillation Signs and Symptoms. *Atrial Fibrillation Diagnosis. *Atrial Fibrillation ...
Nonvalvular atrial fibrillation (AF) is a heart condition. Unlike other types of AF, it is not caused by a faulty valve. Causes ... Atrial fibrillation: Which medications. Atrial fibrillation (A-fib) causes a disruption in the regular rhythm of the heart. ... A common cause of atrial fibrillation is valvular heart disease. But what are the reasons for atrial fibrillation other than ... The heart works less efficiently in people with atrial fibrillation.. What does nonvalvular atrial fibrillation mean? ...
Learn how to live easier with atrial fibrillation. WebMD shows you ways to manage your irregular heartbeat and keep your heart ... "Atrial Fibrillation: Frequently Asked Questions.". Heart & Stroke Information Point: "Physical activity and atrial fibrillation ... A glass of wine at dinner is probably OK for most people with atrial fibrillation. But regularly drinking more than that and ... For some people, the irregular heartbeat of atrial fibrillation (AFib) never causes a problem. For others, it can lead to ...
... learn about atrial fibrillation triggers, tips that may help to avoid triggers, lifestyle tips, and what may cause atrial ... What are the types of atrial fibrillation? Atrial fibrillation is an irregular heart rhythm. There are several types of atrial ... Nonvalvular atrial fibrillation: Get the facts Nonvalvular atrial fibrillation (AF) is a heart condition. Unlike other types of ... Atrial fibrillation is an irregular, rapid heartbeat. During an atrial fibrillation attack, the heart might not pump enough ...
Atrial Fibrillation and Pregnancy. Br Med J 1961; 1 doi: https://doi.org/10.1136/bmj.1.5237.1407 (Published 20 May 1961) Cite ...
Atrial fibrillation affects more than 2 million Americans, a number that continues to increase as the population ages. While ... Atrial fibrillation occurs when the smaller upper chambers of the heart, called atria, get irregular electrical signals that ... Despite its prevalence, atrial fibrillation remains tricky to treat. Medications that maintain a normal heart rhythm often stop ... If the atrial fibrillation persists, the electrophysiologist can touch up the ablation lines inside the heart until ...
Millard concludes "Atrial fibrillation occurred in less than five percent of the entire study population, which is pretty low." ... There May Be No Permanent Cure for Atrial Fibrillation. Researchers say even after irregular heartbeats are treated, they can ... The Link Between Asthma and Atrial Fibrillation. Written by George Citroner. on July 16, 2018 ... states that poorly controlled asthma also brings a significantly increased risk of atrial fibrillation (AFib). ...
In atrial fibrillation, your pulse often doesnt match your heart sounds. The diagnosis of atrial fibrillation is usually ... Some people with atrial fibrillation have periods of normal heartbeats: the atrial fibrillation comes and goes. In many others ... For anyone who has chronic atrial fibrillation, or who may be going in and out of atrial fibrillation without knowing it ( ... However, atrial fibrillation is often a lifelong condition. This is more likely when it has no known cause or results from a ...
The main concern, however, is that atrial fibrillation can lead to the formation of blood clots in the heart, which can travel ... Atrial fibrillation can produce palpitations, shortness of breath, lightheadedness, weakness, and chest pain, or may occur ... Importantly, only about half of the 3 million U.S. patients with atrial fibrillation use anticoagulants. Those who do not use ... More than 3 million Americans have atrial fibrillation, a problem with the electrical system of the heart that causes an ...
Not everyone who develops atrial fibrillation will experience symptoms, but for those who do, they can range from mild to ... Symptoms of atrial fibrillation (AF) can vary from person to person. Some people find that it puts a crimp on everyday ... Causes of atrial fibrillation. Multiple factors can contribute to the development of AF and the abnormal functioning of the ...
Having a parent with atrial fibrillation (AF) strongly increased an offsprings risk of developing this heart rhythm disorder, ... Atrial fibrillation is the most common heart rhythm disorder in the U.S., affecting more than 2 million adults. The prevalence ... Tags: Anticoagulant, Atrial Fibrillation, Blood, Blood Pressure, Chest Pain, Congestive Heart Failure, Drugs, Genes, Genetic, ... "This important research finding will need to be confirmed but it opens up a new avenue of research on atrial fibrillation. Now ...
Atrial fibrillation is a type of arrhythmia in which the electrical signals in the atria, or the two small chambers of the ... Atrial Fibrillation. Facebook Twitter Linkedin Pinterest Print. Atrial fibrillation (A-fib or AF) is the most common type of ... How is atrial fibrillation diagnosed?. Your doctor may suspect that you have atrial fibrillation based on your medical history ... What causes atrial fibrillation?. For many people, the underlying cause of atrial fibrillation is more serious than the ...
心房顫動(英语:Atrial fibrillation,簡稱:AF 或 A-fib),又稱為心房微顫、房顫、心房細動(日本)、心房纖維性顫動、心房纖顫、房性纖顫等,是心臟不正常節律/心律不整的一種,特色是心臟快速而不規則的跳動。心房顫動一開始發生時持續的 ... About: Atrial fibrillation Goto Sponge NotDistinct Permalink An Entity of Type : umbel-rc:AilmentCondition, within Data Space ... Atrial fibrillation (AF or A-fib) is an abnormal heart rhythm characterized by rapid and
Atrial Fibrillation in minutes with SmartDraw. SmartDraw includes 1000s of professional healthcare and anatomy chart templates ... Arrhythmia - Atrial Fibrillation. Create healthcare diagrams like this example called Arrhythmia - Atrial Fibrillation in ... Atrial Fibrillation happens when the electrical signal begins in a different part of the atrium than the SA node. Abnormal ... During atrial fibrillation, the ventricles continue to contract from the hearts electrical activity.. However, the abnormal ...
Mobile Phone Detection of Atrial Fibrillation With Mechanocardiography: The MODE-AF Study (Mobile Phone Detection of Atrial ... Female Sex Is a Risk Modifier Rather Than a Risk Factor for Stroke in Atrial FibrillationShould We Use a CHA2DS2-VA Score ... Atrial Fibrillation Burden in Young Patients With Congenital Heart Disease Zacharias Mandalenakis, Annika Rosengren, Georg ... Treatment of Subclinical Atrial FibrillationDoes One Plus One Always Equal Two? Michael R. Gold ...
Atrial fibrillation begets atrial fibrillation: a study in awake, chronically instrumented goats. Circulation. 1995;92:1954- ... Recently, Wijffels et al8 showed that induction of atrial fibrillation by intermittent rapid atrial pacing in goats led to a ... Unequal atrial stretch in dogs increases dispersion of refractoriness conducive to developing atrial fibrillation. J Cardiovasc ... Nevertheless, it offers the possibility of eradicating atrial fibrillation without surgery.. Atrial RFCA also vagally ...
... is an abnormal heart rhythm. The four chambers of the heart usually beat in a steady, rhythmic ... Stroke is the greatest risk for the patient with atrial fibrillation. Some patients are not aware of atrial fibrillation and in ... Atrial Fibrillation (A Fib) is one of the most common abnormal heart rhythms, particularly once a person reaches the age of 65 ... Click the image to view an animation on Atrial Fibrillation The heart is a pump, and in order to function efficiently, it is ...
Learn atrial fibrillation (A-fib) treatment, symptoms, guidelines, and ablation. What causes atrial fibrillation? ... NEXT: Atrial Fibrillation Slideshow Atrial fibrillation is a(n) .... Atrial fibrillation (also known as AF, A fib, or A-fib) is ... Atrial Fibrillation - Overview.. ,https://www.webmd.com/heart-disease/atrial-fibrillation/atrial-fibrillation-overview, ... Having atrial fibrillation puts a person at risk for _____________.. Atrial fibrillation puts a person at risk for stroke. With ...
... and heart failure in people with decompensated heart failure or permanent atrial fibrillation. ... is a prescription medication used to reduce the risk of hospitalization for atrial fibrillation (AF) in patients with ... Atrial Flutter vs. Atrial Fibrillation. Atrial flutter and atrial fibrillation (AFib) are two types of a heart problem called ... Atrial Fibrillation (AFib): Tips for Living with Atrial Fibrillation. Learn how to live easier with atrial fibrillation. What ...
... patients with atrial fibrillation -- irregular heartbeat -- could receive treatment when having other cardiac surgery, U.S. ... Some patients with atrial fibrillation have no symptoms and are unaware of their condition until its discovered during a ... "Not all patients require surgery for atrial fibrillation," said Dr. Brad Knight, medical director for the Center for Heart ... However, at the Bluhm Cardiovascular Institute, 90 percent of patients with a history of atrial fibrillation were treated when ...
  • A glass of wine at dinner is probably OK for most people with atrial fibrillation. (webmd.com)
  • Some people with atrial fibrillation have periods of normal heartbeats: the atrial fibrillation comes and goes. (womenshealthmag.com)
  • Some people with atrial fibrillation will return to normal rhythm without treatment. (hopkinsmedicine.org)
  • I am frequently asked what I can do to help people with atrial fibrillation (AF or A-fib). (selfgrowth.com)
  • For people with atrial fibrillation, abstinence from alcohol may make the heart beat better. (washingtonpost.com)
  • Sometimes people with atrial fibrillation experience no symptoms and are unaware of the condition. (bidmc.org)
  • Several types of doctors treat people with atrial fibrillation, but electrophysiologists (heart doctors who specialise in heart rhythms) perform catheter ablation procedures. (medtronic.com)
  • People with atrial fibrillation have an increased risk of stroke and heart failure. (nih.gov)
  • Drugs that alter the heart's pace or rhythm are usually the first treatment for people with atrial fibrillation. (nih.gov)
  • In people with atrial fibrillation, blood flow is sluggish in the top chambers of the heart, and blood clots can form there. (fda.gov)
  • But as many as half of the people with atrial fibrillation who could benefit from a blood thinner don't take them. (fda.gov)
  • Offer people with atrial fibrillation a personalised package of care. (nice.org.uk)
  • Do not offer aspirin monotherapy solely for stroke prevention to people with atrial fibrillation. (nice.org.uk)
  • Atrial fibrillation, often called AFib or AF, is the most common type of treated heart arrhythmia. (cdc.gov)
  • For some people, the irregular heartbeat of atrial fibrillation (AFib) never causes a problem. (webmd.com)
  • Atrial fibrillation (or AFib) is a condition that causes an irregular, fast heart rate and rhythm. (healthline.com)
  • states that poorly controlled asthma also brings a significantly increased risk of atrial fibrillation (AFib). (healthline.com)
  • It's easy to say the simple abbreviation for atrial fibrillation, afib or AF, but the topic is actually one of the more complex conditions in heart health. (healthcentral.com)
  • Gebräuchliche Abkürzungen sind AF oder AFib (von englisch Atrial fibrillation), Vfli, VoFli, VHF und VHFli. (dbpedia.org)
  • Please check out the Guide to Atrial Fibrillation , developed by experts in the field to learn more about AFib . (hrsonline.org)
  • The AFib Risk Assessment is an interactive tool designed to help individuals estimate their risk of atrial fibrillation ( AFib ). (hrsonline.org)
  • Atrial fibrillation, known as AF or Afib, is an irregular, rapid heart rate that may cause symptoms like heart palpitations, fatigue, and shortness of breath. (medtronic.com)
  • Atrial Fibrillation (also called AFib or AF) is a quivering or irregular heartbeat (arrhythmia) that can lead to stroke and other heart-related complications. (stvincent.org)
  • Even though untreated atrial fibrillation doubles the risk of heart-related deaths and is associated with a 5-fold increased risk for stroke, many patients are unaware that AFib is a serious condition. (stvincent.org)
  • Atrial fibrillation (AFib) is the most common type of irregular heartbeat. (stvincent.org)
  • The treatment goals of atrial fibrillation (AF or AFib) start with a proper diagnosis through an in-depth examination from a physician. (stvincent.org)
  • Atrial fibrillation (AFib) is a heart rhythm abnormality caused by a problem with the heart's electrical system. (rxlist.com)
  • One of the hallmark AFib symptoms is this so-called fluttering or fibrillation. (rxlist.com)
  • Your risk of getting AFib also increases with age, and white males have a higher incidence of atrial fibrillation. (rxlist.com)
  • Atrial fibrillation that happens in younger people (less than 60 years old), without an obvious cause is called lone AFib. (rxlist.com)
  • While atrial fibrillation (AF), or AFib, reappeared in 73 percent of the people who averaged 13 drinks per week, the rate dropped to 53 percent among patients in the abstinence group - those who weren't supposed to drink at all but, on average, consumed two drinks weekly. (washingtonpost.com)
  • Atrial fibrillation (Afib) contributes significantly to overall cardiovascular risk. (embs.org)
  • Atrial fibrillation or AFib , and ventricular fibrillation or VFib, are both a type of abnormal heart rhythm or heartbeat called an arrhythmia . (rxlist.com)
  • Every year around 75,000 Americans learn that they have atrial fibrillation (AFib)-the most common type of arrhythmia, or abnormal heart rhythm. (agingresearch.org)
  • To prove that this FDA-cleared technology is worth the hype, Apple partnered with Stanford Medicine on a research study on more than 400,000 people to identify irregular heart rhythms and potential atrial fibrillation (Afib) using Apple Watch data. (menshealth.com)
  • Upward of 30 million people worldwide are living with the heart condition known as atrial fibrillation, commonly referred to as AFib. (wpr.org)
  • Atrial fibrillation (also called AFib) is a problem with the rate or rhythm of the heartbeat. (cardiosmart.org)
  • Atrial fibrillation (also called AFib or AF) is the most common form of irregular heart rhythm. (withings.com)
  • Atrial fibrillation (AFib) is an anomaly of the heart's electrical activity. (withings.com)
  • Changes in some genes can cause atrial fibrillation on their own, while changes in other genes affect a person's risk of developing this condition in combination with a variety of environmental and lifestyle factors. (medlineplus.gov)
  • The two-pronged approach gives doctors access to both the inside and outside of the heart at the same time, helping to more completely block the erratic electrical signals that cause atrial fibrillation. (redorbit.com)
  • Non‑pharmacological management includes electrical cardioversion, which may be used to 'shock' the heart back to its normal rhythm, and catheter or surgical ablation to create lesions to stop the abnormal electrical impulses that cause atrial fibrillation. (nice.org.uk)
  • Performed through a standard sternotomy and using the heart-lung bypass machine, these operations were designed to surgically interrupt the "reentrant" electrical pathways found in atrial wall tissue that cause atrial fibrillation and atrial flutter. (hopkinsmedicine.org)
  • These lesions destroy small regions of atrial tissue in areas that give rise to or conduct the aberrant electrical impulses that cause atrial fibrillation. (hopkinsmedicine.org)
  • Conditions that damage or strain the heart commonly cause atrial fibrillation. (healthwise.net)
  • If the electrical signal starts in other areas of the heart or can't travel normally through the heart it can cause atrial fibrillation. (stdavids.com)
  • The most common way to treat atrial fibrillation is with drugs that control your heartbeat. (webmd.com)
  • In recent years, the use of digoxin to treat atrial fibrillation (AF), especially in patients without heart failure (HF), has become controversial. (medpagetoday.com)
  • Doctors at Washington University School of Medicine in St. Louis are performing a new procedure to treat atrial fibrillation, a common irregular heartbeat. (redorbit.com)
  • What surgeries treat atrial fibrillation? (reference.com)
  • Catheter ablation is a minimally invasive procedure which may treat atrial fibrillation. (medtronic.com)
  • Our skilled team of Electrophysiologists are experts and pioneers in procedures to treat atrial fibrillation. (einstein.edu)
  • Yet the firm did garner U.S. marketing approval in December for a separate system that uses freezing technology or cryoablation to treat atrial fibrillation. (xconomy.com)
  • Cardioversion may be used to treat atrial fibrillation. (uwhealth.org)
  • [4] It may also start as other forms of arrhythmia such as atrial flutter that then transform into AF. (wikipedia.org)
  • [4] A-fib and atrial flutter resulted in 193,300 deaths in 2015, up from 29,000 in 1990. (wikipedia.org)
  • Certain other arrhythmias - atrial flutter and atrial tachycardia - may later develop into atrial fibrillation if not treated. (hopkinsmedicine.org)
  • The recommendations apply to adults (18 years or older) with atrial fibrillation, including paroxysmal (recurrent), persistent and permanent atrial fibrillation, and atrial flutter. (nice.org.uk)
  • The AFFELECT -study compares two types of treatment modalities for acute atrial fibrillation or flutter for patients in whom rhythm control is desirable. (centerwatch.com)
  • In atrial fibrillation and flutter, the atria are stimulated to contract very quickly. (medhelp.org)
  • Causes of atrial fibrillation and flutter include dysfunction of the sinus node (the 'natural pacemaker' of the heart) and a number of heart and lung disorders including coronary artery disease, rheumatic heart disease, mitral valve disorders, pericarditis, and others. (medhelp.org)
  • Atrial flutter is most often associated with a heart attack (myocardial infarction) or surgery on the heart. (medhelp.org)
  • Atrial fibrillation or flutter affects about 5 out of 1000 people. (medhelp.org)
  • The normal heart rate is 60 to 100, but in atrial fibrillation/flutter the heart rate may be 100 to 175. (medhelp.org)
  • An ECG shows atrial fibrillation or atrial flutter. (medhelp.org)
  • Treatment varies depending on the cause of the atrial fibrillation or flutter. (medhelp.org)
  • Atrial flutter is usually a short-term problem. (medhelp.org)
  • J. L. Cox, R. D. B. Jaquiss, R. B. Schuessler, and J. P. Boineau, "Modification of the maze procedure for atrial flutter and atrial fibrillation. (hindawi.com)
  • The box lesion group had a 48 percent lower occurrence of atrial flutter and fibrillation in the first weeks following surgery. (drugs.com)
  • Left atrial appendage occlusion removes the most common site for the formation of cardiac emboli. (medpagetoday.com)
  • The Posterior Wall and/or Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation (The PLEA Trial) is a prospective multicenter randomized controlled study that has the overall goal of establishing the efficacy and safety of different ablation techniques for patients with persistent and long-standing persistent atrial fibrillation. (centerwatch.com)
  • St. Vincent performs one-time minimally invasive left atrial appendage closure procedure that reduces the risk of a stroke in non-valvular atrial fibrillation patients. (stvincent.org)
  • Often, the left atrial appendage is also removed during these procedures, since it is widely believed that this is where blood clots tend to form in patients suffering from atrial fibrillation. (hopkinsmedicine.org)
  • Video-assisted bilateral pulmonary vein isolation and left atrial appendage exclusion for atrial fibrillation," Journal of Thoracic and Cardiovascular Surgery , vol. 130, no. 3, pp. 797-802, 2005. (hindawi.com)
  • Percutaneous left atrial appendage transcatheter occlusion to prevent stroke in high-risk patients with atrial fibrillation: early clinical experience," Circulation , vol. 105, no. 16, pp. 1887-1889, 2002. (hindawi.com)
  • Panel B shows the results of a shape analysis of the left atrial appendage (LAA) shape in patients who all have atrial fibrillation but only a group of which proceed to experience a stroke. (utah.edu)
  • This small, umbrella like device gets threaded through a vein in the leg into a specific location in the heart called the left atrial appendage (LAA). (einstein.edu)
  • We offer the Watchman left atrial appendage closure procedure as an option to reduce stroke risk. (uwhealth.org)
  • During the Watchman procedure, surgeons implant the Watchman device to close the left atrial appendage. (uwhealth.org)
  • Symptoms of atrial fibrillation (AF) can vary from person to person. (healthcentral.com)
  • What are the symptoms of atrial fibrillation? (hopkinsmedicine.org)
  • When treatment is successful, patients dramatically reduce their risk of experiencing a stroke, but the drugs don't improve the symptoms of atrial fibrillation," Unger adds. (fda.gov)
  • Refer people promptly [ 1 ] at any stage if treatment fails to control the symptoms of atrial fibrillation and more specialised management is needed. (nice.org.uk)
  • Radiofrequency catheter ablation is not superior to antiarrhythmic drug therapy as first-line treatment in patients with symptomatic paroxysmal atrial fibrillation-but it may be a reasonable alternative. (medpagetoday.com)
  • The goal of ablation therapy is to create scar tissue that isolates the irregular electrical signals and blocks them from spreading over the heart and causing fibrillation. (redorbit.com)
  • After the surgeon has performed the ablations on the outside of the heart, the electrophysiologist uses the catheters inside the heart to attempt to induce a fibrillation, testing the integrity of the ablation lines. (redorbit.com)
  • These procedures including cardioversion or shocking the heart back to normal rhythm, catheter ablation, which is a nonsurgical approach to eliminating atrial fibrillation, and surgical ablation, a surgical approach to eliminating it. (healthcentral.com)
  • Pulmonary vein isolation with catheter ablation is an effective treatment in patients with symptomatic atrial fibrillation refractory or intolerant to antiarrhythmic medications. (hindawi.com)
  • Also summarized here are the publications describing the clinical experience with the cryoballoon catheter ablation in both paroxysmal and persistent atrial fibrillation, its safety and efficacy, and discussions on the technical aspect of the cryoballoon ablation procedure. (hindawi.com)
  • The literature was searched in PubMed from 1950 to February 2011 with the keywords "atrial fibrillation," "cryosurgery," and "catheter ablation" published in English. (hindawi.com)
  • This is an observational multicenter registry of atrial fibrillation catheter ablation performed using the ablation index technology, which has been introduced as a tool predicting ablation lesion depth. (centerwatch.com)
  • Systematic Evaluation of Ablation Techniques for Non-Paroxysmal Atrial Fibrillation. (centerwatch.com)
  • Patients with symptomatic persistent or long-standing persistent atrial fibrillation refractory to pharmacological or routine catheter ablation can be considered for hybrid epicardial-endocardial AF ablation. (springer.com)
  • Long-term outcomes of catheter ablation of atrial fibrillation: a systematic review and meta-analysis. (springer.com)
  • Predictors of recurrence following radiofrequency ablation for persistent atrial fibrillation. (springer.com)
  • Initial experience of sequential surgical epicardial-catheter endocardial ablation for persistent and long-standing persistent atrial fibrillation with long-term follow-up. (springer.com)
  • Thoracoscopic video-assisted pulmonary vein antrum isolation, ganglionated plexus ablation, and periprocedural confirmation of ablation lesions: first results of a hybrid surgical-electrophysiological approach for atrial fibrillation. (springer.com)
  • Hybrid thoracoscopic surgical and transvenous catheter ablation of atrial fibrillation. (springer.com)
  • The use of ablation in the treatment of atrial fibrillation has captured the greatest attention in journals and at national meetings, and it is a major focus of this book. (springer.com)
  • New evidence supports ablation for heart failure patients with atrial fibrillation March 04, 2020, 03:00 p.m. (mayoclinic.org)
  • Surgeries for atrial fibrillation include catheter ablation surgery and MAZE surgery, according to Healthline. (reference.com)
  • What is a cathetar ablation for atrial fibrillation? (reference.com)
  • A catheter ablation for atrial fibrillation is a procedure in which a doctor guides a catheter into the heart through a vein and uses the catheter to deliv. (reference.com)
  • The Johns Hopkins Minimally-Invasive Cardiac Surgical Program currently offers minimally-invasive surgical radiofrequency ablation for patients who suffer from atrial fibrillation . (hopkinsmedicine.org)
  • If you have atrial fibrillation that medication does not help, your doctor may recommend catheter ablation. (medtronic.com)
  • If your doctor has advised you that catheter ablation may be the best treatment for your atrial fibrillation, you may have some questions about what to expect before, during, and after the catheter ablation procedure. (medtronic.com)
  • Compared with medications, a procedure called catheter ablation did not significantly reduce the risk of death or serious complications from atrial fibrillation. (nih.gov)
  • It hasn't been clear whether catheter ablation is more effective than drugs in reducing the risk of death or serious complications of atrial fibrillation. (nih.gov)
  • The team randomly assigned patients with atrial fibrillation to either receive drugs or undergo ablation. (nih.gov)
  • However, people in the ablation group had a lower risk of their fibrillation recurring during the study, and a reduced risk of being hospitalized. (nih.gov)
  • Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial. (nih.gov)
  • Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial. (nih.gov)
  • Linear left atrial lesions in minimally invasive surgical ablation of persistent atrial fibrillation: techniques for assessing conduction block across surgical lesions," Heart Rhythm , vol. 6, no. 12, pp. (hindawi.com)
  • Treatment of atrial fibrillation with antiarrhythmic drugs or radiofrequency ablation: two systematic literature reviews and meta-analyses," Circulation: Arrhythmia and Electrophysiology , vol. 2, no. 4, pp. 349-361, 2009. (hindawi.com)
  • HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and followup. (hindawi.com)
  • A report of the heart rhythm society (HRS) task force on catheter and surgical ablation of atrial fibrillation," Heart Rhythm , vol. 4, pp. 816-861, 2007. (hindawi.com)
  • Mechanisms of arrhythmia recurrence after video-assisted thoracoscopic surgery for the treatment of atrial fibrillation: insights from electrophysiological mapping and ablation," Journal of Cardiovascular Electrophysiology , vol. 20, no. 12, pp. 1313-1320, 2009. (hindawi.com)
  • Catheter ablation for atrial fibrillation: are results maintained at 5 years of follow-up? (hindawi.com)
  • Ablation involves destroying targeted regions of the atria with the goal of either isolating triggers of spurious electrical activity or functionally separating the atrial wall into small enough segments that the putative mechanism of the arrhythmia can no longer be sustained. (utah.edu)
  • In patients who are symptomatic from atrial fibrillation or already suffering from heart failure or heart damage, ablation may be considered. (einstein.edu)
  • The heart procedure improved patients' quality of life and symptoms Catheter ablation, a common cardiovascular procedure, appears no more effective than drug therapies in preventing strokes, deaths, and other complications in patients with atrial fibrillation. (nih.gov)
  • [ 2 ] For more information on left atrial catheter ablation see Percutaneous balloon cryoablation for pulmonary vein isolation in atrial fibrillation (NICE interventional procedure guidance 427), Percutaneous endoscopic catheter laser balloon pulmonary vein isolation for atrial fibrillation (NICE interventional procedure guidance 399) and Percutaneous (non-thoracoscopic) epicardial catheter radiofrequency ablation for atrial fibrillation (NICE interventional procedure guidance 294). (nice.org.uk)
  • For more information on left atrial surgical ablation without thoracotomy see Thoracoscopic epicardial radiofrequency ablation for atrial fibrillation (NICE interventional procedure guidance 286). (nice.org.uk)
  • Patients with low blood levels of the CITP/MMP-1 ratio and elevated levels of PICP have a high risk of developing atrial fibrillation and that it recurred after cardiac ablation. (medindia.net)
  • To help prevent atrial fibrillation, some risk factors may be controlled or modified. (medtronic.com)
  • The best way to prevent atrial fibrillation is to lower your risk of heart disease. (aafp.org)
  • Do Dreams Prevent Atrial Fibrillation? (ucsf.edu)
  • Compounds like S2814A prevent atrial fibrillation by preventing the occurrence of Delayed After Depolarizations. (escardio.org)
  • Strict blood pressure control in midlife can help to prevent atrial fibrillation-associated dementia, said study. (medindia.net)
  • Atrial fibrillation is one of the most common forms of cardiac disturbances, diagnosed in an estimated 2.7 million to 6.1 million people in the United States, with prevalence increasing with age. (medscape.com)
  • Small spikes in traffic-related smog seem to trigger clinically relevant atrial arrhythmias in patients with known cardiac disease. (medpagetoday.com)
  • For some patients, it's a difficult way to live," says Phillip S. Cuculich, MD, assistant professor of medicine at Washington University School of Medicine in St. Louis and a cardiac electrophysiologist who treats patients with atrial fibrillation at Barnes-Jewish Hospital. (redorbit.com)
  • If you have other cardiac surgery that you need, like bypass surgery or valve surgery, and you have atrial fibrillation, the Cox-Maze procedure is an excellent choice to do at the same time," Cuculich says. (redorbit.com)
  • CHICAGO, April 30 (UPI) -- More U.S. patients with atrial fibrillation -- irregular heartbeat -- could receive treatment when having other cardiac surgery, U.S. researchers say. (upi.com)
  • Dr. Richard Lee , surgical director of the Center for Heart Rhythm Disorders at Northwestern Memorial's Bluhm Cardiovascular Institute, said patients who are undergoing surgery for other cardiac issues, don't always have their atrial fibrillation problem fixed. (upi.com)
  • This study indicates that atrial fibrillation should be surgically treated when a patient is undergoing another cardiac surgery procedure," Lee said in a statement. (upi.com)
  • However, at the Bluhm Cardiovascular Institute, 90 percent of patients with a history of atrial fibrillation were treated when they had cardiac surgery. (upi.com)
  • Patients with atrial fibrillation, the most frequent cardiac arrhythmia, are closer to accessing personalized medicine. (eurekalert.org)
  • The study, results show that it is possible to monitor and predict individual progression of atrial fibrillation from cardiac electrical signals obtained from implantable devices (pacemakers or defibrillators). (eurekalert.org)
  • This technology can be used to monitor cardiac electrical activity during episodes of atrial fibrillation, thus establishing disease status and the rate of progression. (eurekalert.org)
  • Atrial fibrillation is the most common sustained cardiac arrhythmia, and estimates suggest its prevalence is increasing. (nice.org.uk)
  • Atrial fibrillation (AF) is the most common sustained cardiac rhythm disturbance, increasing in prevalence with age [ 1 ]. (hindawi.com)
  • Treatment of atrial fibrillation and its aftermath can also add days to the hospital stay of the cardiac surgical patient. (springer.com)
  • Experimental studies have led to a greater understanding of the mechanism of atrial fibrillation and potential precipitating factors in the cardiac surgical patient. (springer.com)
  • Each chapter deals with a different aspect of Atrial Fibrillation and was authored by internationally recognized experts in the evolving field of cardiac electrophysiology. (springer.com)
  • Because Atrial Fibrillation is so prevalent and affects all areas of medicine, the information in this book will be useful to cardiologists, cardiac surgeons, researchers, and all those in the medical field. (springer.com)
  • The doctor said that she has cardiac fibrosis which cause the atrial fibrillation. (healingwell.com)
  • I would like to know if somebody has atrial fibrillation due to cardiac fibriosis and if so, what steps did you take to take care of it. (healingwell.com)
  • disorder of cardiac rhythm characterized by rapid, irregular atrial impulses and ineffective atrial contractions. (fpnotebook.com)
  • Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans, which is believed to be maintained by rapid reentry sources (rotors). (embs.org)
  • If ventricular fibrillation isn't treated immediately, the patient will have a "sudden death" or " cardiac arrest " and die. (rxlist.com)
  • Atrial fibrillation (AF) is a cardiac rhythm disturbance in which the atria, the upper chambers of the heart, undergo uncontrolled and uncoordinated electrical activation so that contraction of the atria contributes almost nothing to cardiac output. (utah.edu)
  • Atrial fibrillation pathophysiology is the terminology used to describe the progression of physiological changes associated with a cardiac arrhythmia . (wisegeek.com)
  • Atrial fibrillation, a cardiac ailment affects more than 33.5 million people in the world. (medindia.net)
  • It has been suggested that inflammation can have a role in the development of atrial arrhythmias after cardiac surgery and that genetic predisposition to develop postoperative complications exists. (bioportfolio.com)
  • The purpose of this study is to determine if preforming a posterior left pericardiotomy prevents atrial fibrillation after cardiac surgery. (bioportfolio.com)
  • Postoperative atrial fibrillation is a common complication after cardiac surgery and is associated with an elevation of morbidity and mortality. (bioportfolio.com)
  • New methods of achieving prompt cardioversion with minimal disruption of patient care, and prevention of the thromboembolic complications of atrial fibrillation, are also important therapeutic initiatives. (springer.com)
  • There is not a consensus on the best long term management of atrial fibrillation but many doctors feel it is important to try everything, including cardioversion (shock) to try to get the heart back into regular rhythm. (medhelp.org)
  • Treatment of atrial fibrillation also involves resetting or restoring the heart's normal sinus rhythm, called cardioversion. (bidmc.org)
  • [ 1 ] The Guideline Development Group defined 'promptly' as no longer than 4 weeks after the final failed treatment or no longer than 4 weeks after recurrence of atrial fibrillation following cardioversion when further specialised management is needed. (nice.org.uk)
  • Others are in atrial fibrillation for seven days or longer ( persistent AF). (hopkinsmedicine.org)
  • It is meant for people who have had certain types of atrial fibrillation (paroxysmal or persistent AF) in the past, but are now in normal rhythm. (medicinenet.com)
  • Persistent atrial fibrillation lasts for at least a week and doesn't stop without treatment to restore a normal rhythm. (bidmc.org)
  • In patients with permanent atrial fibrillation , Multaq doubles the risk of death, stroke and hospitalization for heart failure. (medicinenet.com)
  • This complication can occur with either paroxysmal (intermittent) or chronic (permanent) atrial fibrillation. (uptodate.com)
  • Dronedarone in high-risk permanent atrial fibrillation. (nih.gov)
  • We hypothesized that dronedarone would reduce major vascular events in high-risk permanent atrial fibrillation. (nih.gov)
  • We assigned patients who were at least 65 years of age with at least a 6-month history of permanent atrial fibrillation and risk factors for major vascular events to receive dronedarone or placebo. (nih.gov)
  • Dronedarone increased rates of heart failure, stroke, and death from cardiovascular causes in patients with permanent atrial fibrillation who were at risk for major vascular events. (nih.gov)
  • Leads V4 and V5 of an electrocardiogram showing atrial fibrillation with somewhat irregular intervals between heart beats, no P waves , and a heart rate of about 150 beats per minute. (wikipedia.org)
  • The diagnosis of atrial fibrillation is usually confirmed with an electrocardiogram (EKG). (womenshealthmag.com)
  • Your doctor will diagnose atrial fibrillation on an electrocardiogram (EKG). (rxlist.com)
  • See 'The electrocardiogram in atrial fibrillation' and 'Actions of angiotensin II on the heart' and 'Epidemiology of and risk factors for atrial fibrillation' . (uptodate.com)
  • When atrial fibrillation (AF) is suspected during auscultation of the heart with irregularly irregular beats, obtaining a 12-lead electrocardiogram (ECG) is the next step. (medscape.com)
  • The best way to find out if you have atrial fibrillation is to have an electrocardiogram (EKG or ECG). (healthwise.net)
  • Risk assessment for incident heart failure in individuals with atrial fibrillation. (framinghamheartstudy.org)
  • Atrial fibrillation ( AF or A-fib ) is an abnormal heart rhythm (arrhythmia) characterized by the rapid and irregular beating of the atrial chambers of the heart . (wikipedia.org)
  • Atrial fibrillation is the most common serious abnormal heart rhythm and, as of 2020, affects more than 33 million people worldwide. (wikipedia.org)
  • Complications of atrial fibrillation can occur at any age, although some people with this heart condition never experience any health problems associated with the disorder. (medlineplus.gov)
  • Atrial fibrillation is a problem with your heart 's electrical activity. (webmd.com)
  • What Is Digoxin's Role in Atrial Fibrillation With and Without Heart Failure? (medpagetoday.com)
  • Treatment for atrial fibrillation (AF) depends on how severe or frequent the symptoms are and whether you already have heart disease. (news-medical.net)
  • A common cause of atrial fibrillation is valvular heart disease. (medicalnewstoday.com)
  • But what are the reasons for atrial fibrillation other than valvular heart disease? (medicalnewstoday.com)
  • Atrial fibrillation , often referred to as A-fib or AF, means that the heart works less efficiently, which can cause several health problems. (medicalnewstoday.com)
  • Atrial' means to do with the atria or the top two chambers of the heart. (medicalnewstoday.com)
  • During an atrial fibrillation attack, the heart might not pump enough oxygen-rich blood to the rest of the body, leading to symptoms including weakness, light-headedness, and dizziness. (medicalnewstoday.com)
  • Atrial fibrillation (A-fib) itself is not usually life-threatening but it can lead to serious complications, such as a stroke or new or worsening heart failure . (medicalnewstoday.com)
  • While not fatal in itself, patients who suffer from atrial fibrillation are at increased risk of stroke and congestive heart failure. (redorbit.com)
  • Atrial fibrillation occurs when the smaller upper chambers of the heart, called atria, get irregular electrical signals that disrupt the coordinated pumping of blood through the heart to the rest of the body. (redorbit.com)
  • A complete scar that crosses through the full thickness of the heart wall will more permanently block atrial fibrillation signals. (redorbit.com)
  • Atrial fibrillation is a heart rhythm disorder that causes a rapid and irregular heartbeat. (womenshealthmag.com)
  • Atrial fibrillation affects the upper two chambers of the heart, the atria. (womenshealthmag.com)
  • During atrial fibrillation, the heart beats at 80 to 160 beats per minute, and is very irregular: beat. (womenshealthmag.com)
  • In atrial fibrillation, your pulse often doesn't match your heart sounds. (womenshealthmag.com)
  • More than 3 million Americans have atrial fibrillation, a problem with the electrical system of the heart that causes an irregular heart rhythm. (fda.gov)
  • The main concern, however, is that atrial fibrillation can lead to the formation of blood clots in the heart, which can travel to the brain and cause a stroke. (fda.gov)
  • There are a number of treatments -- drugs and procedures -- intended to correct the fundamental heart rhythm problem in patients with atrial fibrillation, but the main focus of treatment is to try to decrease the rate of stroke by preventing the formation of these blood clots. (fda.gov)
  • Having a parent with atrial fibrillation (AF) strongly increased an offspring's risk of developing this heart rhythm disorder, according to a study of participants in the National Heart, Lung, and Blood Institute's (NHLBI) Framingham Heart Study. (news-medical.net)
  • Atrial fibrillation is the most common heart rhythm disorder in the U.S., affecting more than 2 million adults. (news-medical.net)
  • Atrial fibrillation is most common in people over the age of 50, especially white men, and in those who have other types of heart disease. (hopkinsmedicine.org)
  • In atrial fibrillation the pulse, which reflects the activity of the ventricles, is often mismatched with the heart sounds because not all of the atrial beats are reaching the ventricles. (hopkinsmedicine.org)
  • 1 Atrial fibrillation usually accompanies disorders such as rheumatic and coronary heart disease, heart failure, mitral valve prolapse, hypertension, cardiomyopathies, hyperthyroidism, and the postoperative state but can occur in the absence of any recognized abnormality (lone atrial fibrillation) in at least 10% of cases. (ahajournals.org)
  • Atrial Fibrillation ( A Fib ) is one of the most common abnormal heart rhythms, particularly once a person reaches the age of 65 years, (earlier in many patients). (hrsonline.org)
  • Atrial fibrillation may be a primary electrical abnormality of the heart, be associated with underlying heart problems including problems with heart valves, coronary arteries, heart muscle, congestive heart failure or be related to problems with the thyroid gland or other disorders of metabolism. (hrsonline.org)
  • Atrial fibrillation (also known as AF, A fib, or A-fib) is the most common, abnormal rhythm of the heart. (medicinenet.com)
  • What happens within the heart during atrial fibrillation? (medicinenet.com)
  • Damage to the electrical system within the heart causes atrial fibrillation. (medicinenet.com)
  • With atrial fibrillation, heart contractions are more rapid, but weaker than regular heart contractions, resulting in slow blood flow in the atrium. (medicinenet.com)
  • Not all patients require surgery for atrial fibrillation," said Dr. Brad Knight, medical director for the Center for Heart Rhythm Disorders. (upi.com)
  • Baseline clinical characteristics of all patients were collected, including a history of stroke or systemic embolism, heart failure, diabetes mellitus, heart failure, hypertension, and other medical conditions, as well as assessment stroke risk factor scores for patients with nonrheumatic atrial fibrillation. (elsevier.com)
  • The authors aim to urge physicians treating patients in endemic areas to consider Lyme carditis in the workup for patients with atrial fibrillation and unexplained heart block, as the associated atrioventricular nodal complications may be fatal. (nih.gov)
  • in some, a pattern of repeated short episodes is maintained for years, whereas in others it progresses rapidly to longer episodes associated with atrial dilatation and major difficulties in controlling heart rhythm. (eurekalert.org)
  • If you have atrial fibrillation, a common heart rhythm disorder (arrhythmia), you might need to change how you manage the condition during your pregnancy. (mayoclinic.org)
  • Atrial fibrillation increases your risk of developing blood clots in your heart. (mayoclinic.org)
  • Drug treatments include anticoagulants to reduce the risk of stroke and antiarrhythmics to restore or maintain the normal heart rhythm or to slow the heart rate in people who remain in atrial fibrillation. (nice.org.uk)
  • They do not apply to people with congenital heart disease precipitating atrial fibrillation. (nice.org.uk)
  • GUIDE-IT - GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT) -The goal of this US prospective outpatient AF registry is to identify real world treatment patterns in patients with AF(atrial fibrillation), outside of randomized controlled trials. (centerwatch.com)
  • In atrial fibrillation, the upper chambers of the heart (the atria) beat irregularly (quiver) instead of beating effectively to move blood into the ventricles. (stvincent.org)
  • We believe that the hybrid approach should be considered in patients who either have had unsuccessful catheter ablations or have significant structural heart disease evident by enlarged left atrial size or atrial fibrosis. (springer.com)
  • Doctors and surgeons who have training in heart rhythm disorders study genetics, causes, diagnosis and treatment options for atrial fibrillation and other heart rhythm disorders in Mayo Clinic's Cardiovascular Research Center . (mayoclinic.org)
  • Is there any evidence that this class of drug (fluoxetine, paroxetine, etc) can precipitate atrial fibrillation in an otherwise healthy 45 year old heart? (medhelp.org)
  • Atrial fibrillation causes an irregular heart rate. (rxlist.com)
  • When atrial fibrillation is new in onset or poorly controlled by medications you will often feel your heart racing. (rxlist.com)
  • If your heart goes into atrial fibrillation you may experience dangerous and frightening symptoms. (rxlist.com)
  • Because of the irregular and chaotic flow of blood through the heart, small blood clots can form in the heart chambers when you have atrial fibrillation. (rxlist.com)
  • If you think you are experiencing atrial fibrillation and have chest pain, feel faint, feel a very rapid heart rate (greater than 100 beats per minute), or have any signs or symptoms of a stroke, call 911 immediately or have someone call 911 for you. (rxlist.com)
  • One of the risks of having open-heart surgery or coronary artery bypass graft surgery (CABG) is atrial fibrillation. (rxlist.com)
  • Once atrial fibrillation is confirmed or suspected your doctor will perform further tests to check your heart muscle and heart valves and to screen for blood clots. (rxlist.com)
  • A new study presented at the American Heart Association Scientific Session conference has found that patients with atrial fibrillation (AF) also show signs of asymptomatic brain injury. (genengnews.com)
  • Researchers from the Intermountain Medical Center Heart Institute in Salt Lake City have found that patients with atrial fibrillation (AF) also show signs of asymptomatic brain injury. (genengnews.com)
  • We think patients with atrial fibrillation experience chronic, subclinical cerebral injuries," said Oxana Galenko, Ph.D., a molecular biologist at the Intermountain Medical Center Heart Institute, and the study's lead investigator. (genengnews.com)
  • Atrial fibrillation is an irregular and sometimes rapid heartbeat that can lead to blood clots, stroke, heart failure, and other heart-related problems. (genengnews.com)
  • Atrial fibrillation (AF) is an abnormal heart rhythm originating in the top two chambers of your heart (the atria). (bidmc.org)
  • During atrial fibrillation, the atria beat out of sync with the lower two chambers of the heart (the ventricles). (bidmc.org)
  • Paroxysmal atrial fibrillation is when AF comes and goes, lasting for a few seconds to a few days before returning to a normal heart rhythm. (bidmc.org)
  • While the heart is in atrial fibrillation, it may not be able to pump effectively, potentially leading to a reduction in the heart's overall ability to pump blood to the rest of the body. (bidmc.org)
  • More recently, doctors have discovered that the abnormal electrical impulses seen in atrial fibrillation often start in the pulmonary (lung) veins, which drain blood from the lungs into the left atrium of the heart. (bidmc.org)
  • Atrial fibrillation is a condition associated with increased heart rate and irregular rhythm, which requires immediate attention. (medindia.net)
  • Treating atrial fibrillation (AF) is important since atrial fibrillation causes unpleasant symptoms like shortness of breath, fatigue, or weakness, and may cause a stroke and heart failure. (medtronic.com)
  • For patients with atrial fibrillation, the electrophysiologists (cardiologists specializing in heart rhythms) at Cedars-Sinai provide highly individualized care for patients with this disease. (cedars-sinai.edu)
  • Atrial fibrillation is the most common heart-rhythm disorder among older adults. (nih.gov)
  • This uses a flexible tube threaded through a blood vessel to destroy the abnormal heart tissue causing the fibrillation. (nih.gov)
  • Electrical connections between left superior pulmonary vein, left atrium, and ligament of Marshall: implications for mechanisms of atrial fibrillation," The American Journal of Physiology-Heart and Circulatory Physiology , vol. 290, no. 1, pp. (hindawi.com)
  • Mechanisms proposed to explain the benefit of angiotensin blockade found in the early studies included the direct effects of angiotensin blockade on the structural and electrical properties of the atria, as well as the indirect influence of improved control of heart failure and hypertension (in patients with these conditions), both of which are known risk factors for atrial fibrillation (AF) [ 1 ]. (uptodate.com)
  • Atrial fibrillation and ventricular fibrillation are heart conditions that include the term " fibrillation . (rxlist.com)
  • When defined as related to the heart, 'fibrillation' refers to a very rapid irregular contractions of the heart's muscle fibers. (rxlist.com)
  • One of the main differences between these two heart conditions is that ventricular fibrillation is life threatening if treatment isn't begun immediately, while atrial fibrillation generally is not immediately life threatening, but can cause problems with the heart function that are very dangerous if not treated effectively. (rxlist.com)
  • Sleep disruption may be linked to the irregular, rapid heart rate known as atrial fibrillation (AF), which raises the risk of stroke, dementia, heart attack and death, making sleep quality a modifiable risk factor for those conditions. (ucsf.edu)
  • Atrial fibrillation may be treated with medications to either slow the heart rate to a normal range (rate control) or revert the heart rhythm to normal (rhythm control). (prweb.com)
  • Atrial fibrillation, also called "a-fib" or "atrial fib," is an irregular heart rhythm. (hubpages.com)
  • In patients who are particularly symptomatic from atrial fibrillation (altered heart signals), surgical correction may be considered. (einstein.edu)
  • A Maze procedure is a surgical intervention that creates areas of scar tissue that block the abnormal heart signals that create the atrial fibrillation, thereby restoring a normal heart rhythm. (einstein.edu)
  • Using data from 4,976 people taking part in an Internet-based study on heart health, the researchers analyzed participants' exposure to secondhand smoke and whether or not they had atrial fibrillation. (foxnews.com)
  • The risk was even higher among people who did not have other risk factors for atrial fibrillation, they note in a report online September 1 in the journal Heart Rhythm. (foxnews.com)
  • Apple in conjunction with Stanford Medicine is launching a new study on atrial fibrillation that aims to detect heart rate irregularities using a consumer-grade wearable device - Apple Watch. (appleinsider.com)
  • Atrial fibrillation is a change in the normal rhythm of the heart characterized by irregular beat, which is generally imperceptible by the sufferer. (appleinsider.com)
  • Updated-03/01/11, 8:30 am ET] Investors have been getting behind a Marlborough, MA-based firm that is working on a potentially better way to treat an irregular heart rhythm known as atrial fibrillation. (xconomy.com)
  • Older men who were big during their 20s face an increased risk of suffering from atrial fibrillation, or abnormal heart rhythm. (scienceblog.com)
  • MONDAY, April 21 -- Adding one step and no more than 20 seconds to heart surgery can greatly improve the results of an operation to treat the common irregular heartbeat called atrial fibrillation, according to a new report. (drugs.com)
  • During atrial fibrillation, the upper chambers (atria) of the heart beat rapidly and quiver instead of contracting, drastically reducing the amount of blood they pump. (drugs.com)
  • The procedure, which creates a series of ablations in the heart muscle, is highly effective at curing atrial fibrillation, the Washington University scientists said. (drugs.com)
  • More than 2 million people in the United States have atrial fibrillation, which can cause fatigue, shortness of breath, heart palpitations and stroke. (drugs.com)
  • The American Heart Association has more about atrial fibrillation. (drugs.com)
  • In atrial fibrillation, a problem with the heart's electrical system causes the two upper parts of the heart, the atria, to quiver, or fibrillate. (healthwise.net)
  • Atrial fibrillation can also lead to heart failure . (healthwise.net)
  • Rate-control medicines to keep your heart from beating too fast during atrial fibrillation. (healthwise.net)
  • Atrial fibrillation is often the result of heart disease or damage. (healthwise.net)
  • However, if you notice your heart suddenly races or if you have uneven heartbeats that last several minutes, you may have a condition known as atrial fibrillation. (cardiosmart.org)
  • Heart quivering is the most common initial sign of atrial fibrillation. (wisegeek.com)
  • Once an atrial fibrillation has been detected, re-establishing regular heart rhythm, also known as normal sinus rhythm, is the goal of treatment. (wisegeek.com)
  • Atrial fibrillation is the most common alteration of the heart rhythm (arrhythmia). (medindia.net)
  • Atrial fibrillation is a condition with irregular heart rhythm. (medindia.net)
  • Atrial fibrillation is a fast and abnormal pattern of contractions in the upper part of the heart. (stdavids.com)
  • The objective of this registry is the characterization of patients with atrial fibrillation (AF) with confirmed valvular heart disease (VHD) who are prescribed edoxaban in a real-life clin. (bioportfolio.com)
  • Atrial fibrillation is one type of heart rhythm disorder. (uwhealth.org)
  • Registry to explore characteristics, use and management of new oral anticoagulants (NOAC) and vitamin K antagonists (VKA) treatment among patients with atrial fibrillation (AF) and recent cerebrovascular disease in a "real-world" setting at a stroke centre. (centerwatch.com)
  • Atrial fibrillation (AF) is the most common type of arrhythmia . (medlineplus.gov)
  • [ 1 , 2 ] AF is an arrhythmia or irregular heartbeat with uncoordinated atrial activation and ineffective atrial contraction, leading to inadequate blood flow into the ventricles. (medscape.com)
  • Atrial fibrillation is the most common type of recurrent arrhythmia, affecting more than 3 million people in the United States. (medlineplus.gov)
  • The reality that atrial fibrillation (AF) is the most frequently encountered arrhythmia in clinical practice, and that the incidence and prevalence of AF appears to be on the rise, is well known. (medscape.com)
  • For many people, the underlying cause of atrial fibrillation is more serious than the arrhythmia itself. (hopkinsmedicine.org)
  • Create healthcare diagrams like this example called Arrhythmia - Atrial Fibrillation in minutes with SmartDraw. (smartdraw.com)
  • Atrial fibrillation is the most frequent chronic sustained arrhythmia, affecting more than 30 million people worldwide and an estimated 600,000 or more people in Spain. (eurekalert.org)
  • This would allow, after the initiation of atrial fibrillation episodes, "optimal timing of the most appropriate medical treatment, avoiding delays until the arrhythmia has progressed to a state that is harder to control," explained CNIC researcher Dr José Jalife, an author on the study. (eurekalert.org)
  • According to Dr Filgueiras, "this technology opens up enormous possibilities in personalized medicine for atrial fibrillation patients because it allows us to determine the progression rate of the arrhythmia in each individual and to optimize the timing of medical intervention with current treatment options. (eurekalert.org)
  • The CIBC Center continues to work in close collaboration with Dr. Nassir Marrouche and his team at the Comprehensive Arrhythmia Research and Management (CARMA) Center to advance the state of technology used for the monitoring and treatment of Atrial Fibrillation (AF). (utah.edu)
  • The campaign aimed to raise public awareness about atrial fibrillation, the most common form of arrhythmia. (gulf-times.com)
  • Atrial fibrillation (say "AY-tree-uhl fih-bruh-LAY-shun") is the most common type of irregular heartbeat ( arrhythmia ). (healthwise.net)
  • Atrial fibrillation is one of the most common arrhythmia. (i4u.com)
  • Atrial fibrillation (AF) is the most common arrhythmia in clinical practice with a prevalence reaching 5% in patients older than 65 years and an incidence that increases progressively with. (bioportfolio.com)
  • Recent research shows an increased prevalence of subclinical, asymptomatic, atrial fibrillation in patients with type 2 diabetes mellitus. (medpagetoday.com)
  • Atrial fibrillation (AF) can often be asymptomatic, leading to difficulties in diagnosis and untreated risks for morbidity and mortality. (elsevier.com)
  • Despite being asymptomatic in many cases, atrial fibrillation predisposes patients to an increased risk of life-threatening strokes. (gulf-times.com)
  • It is probable that in some of these patients, the atria remodel over a period of time (see below), owing to the frequent recurrence of fast atrial rates, and develop sustained atrial fibrillation, which is then much more difficult to cure with RFCA. (ahajournals.org)
  • Given the high prevalence of sleep problems and substantial negative impacts of atrial fibrillation, prospective and randomized clinical trials are needed to assess whether interventions that improve sleep quality can reduce the incidence of atrial fibrillation and recurrence among those who already have the disease," said senior author Gregory Marcus , MD, MAS, a UCSF Health cardiologist and director of clinical research in the UCSF Division of Cardiology . (ucsf.edu)
  • Familial atrial fibrillation is an inherited abnormality of the heart's normal rhythm. (medlineplus.gov)
  • Atrial fibrillation is characterized by episodes of uncoordinated electrical activity (fibrillation) in the heart's upper chambers (the atria), which cause a fast and irregular heartbeat. (medlineplus.gov)
  • During atrial fibrillation, the ventricles continue to contract from the heart's electrical activity. (smartdraw.com)
  • Like more than 2 million people in the United States, the Cheshire, Conn., teacher and former school administrator suffered from atrial fibrillation, a disorder in which the heart's upper chambers quiver instead of beating effectively. (latimes.com)
  • Atrial fibrillation is a problem with the heart's electrical system . (healthwise.net)
  • Defined by a chaotic rhythm originating in the atria, or the heart's upper chambers, atrial fibrillation pathophysiology is initiated by a disruption in the heart's electrical impulses. (wisegeek.com)
  • Treatment administered for atrial fibrillation is based on re-establishing and maintaining the heart's natural rhythm with medication and, in some cases, surgery. (wisegeek.com)
  • 2019). Complications from Atrial Fibrillation. (cdc.gov)
  • Mayo Clinic study shows AI could enable accurate, inexpensive screening for atrial fibrillation Aug. 01, 2019, 11:30 p.m. (mayoclinic.org)
  • Mayo Clinic Q and A: Treating atrial fibrillation with blood thinners -- understanding the benefits and risks May 21, 2019, 03:00 p.m. (mayoclinic.org)
  • Younger patients have fewer periprocedural complications, thus avoiding the age-related atrial substrate modification [2] that leads to AF perpetuation and reduced chance of AF sinus rhythm maintenance. (medscape.com)
  • With atrial fibrillation , control of electrical activity in the upper chambers becomes disorganized and the atria fibrillate (quiver or twitch quickly) causing an irregular rhythm. (hrsonline.org)
  • Multaq is contraindicated in patients in atrial fibrillation (AF) who will not or cannot be cardioverted into normal sinus rhythm. (medicinenet.com)
  • See 'Atrial fibrillation: Anticoagulant therapy to prevent embolization' and 'Prevention of embolization prior to and after restoration of sinus rhythm in atrial fibrillation' . (uptodate.com)
  • Once rhythm is restored and normal atrial rhythm is able to persist, there is a gradual reversal of the remodeling. (selfgrowth.com)
  • Dronedarone restores sinus rhythm and reduces hospitalization or death in intermittent atrial fibrillation. (nih.gov)
  • The irregular rhythm from atrial fibrillation may begin to last longer and longer or cause worsening symptoms at which point it will need to be treated and controlled. (rxlist.com)
  • The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study showed that rhythm-control treatment of patients with atrial fibrillation (AF) offered no survival advantage over a rate-control strategy. (springer.com)
  • Falk RH, Knowlton AA, Bernard SA, Gotlieb NE, Battinelli NJ (1987) Digoxin for converting recent-onset atrial fibrillation to sinus rhythm. (springer.com)
  • Atrial fibrillation pathophysiology frequently necessitates the administration of anti-arrhythmic and anticoagulant medications to restore normal sinus rhythm and prevent blood clots . (wisegeek.com)
  • Atrial fibrillation resulting from coronary artery disease can be prevented. (womenshealthmag.com)
  • The foci were located at sites where atrial tachycardias have been noted in other studies, ie, near the sinus node and venae ostia, the coronary sinus in the right atrium and pulmonary veins in the left. (ahajournals.org)
  • Prospective, multicenter, randomized trial, intended to compare three prophylactic strategies of atrial fibrillation in patients with coronary artery disease and without history of atrial fibrillation. (centerwatch.com)
  • On admittance to hospital I was diagnosed as having atrial fibrillation and was sent to coronary care overnight. (medhelp.org)
  • My husband has had two episodes of atrial fibrillation in the past year. (hubpages.com)
  • Doctors try to treat it by controlling blood pressure and other factors, but the new study "presents a compelling argument for alcohol abstinence as part of the successful management of atrial fibrillation," writes Anne Gillis of the University of Calgary in an editorial accompanying the study. (washingtonpost.com)
  • As a result, I've done extensive research on the condition, as well as on the complications of atrial fibrillation, by reading everything I could get my hands on and by talking to numerous doctors, nurses, and other health care professionals. (hubpages.com)
  • As you might imagine, I was more concerned with the possible complications of atrial fibrillation than I was with the causes. (hubpages.com)
  • Colilla S, Crow A, Petkun W, Singer DE, Simon T, Liu X. Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population. (cdc.gov)
  • Despite its prevalence, atrial fibrillation remains tricky to treat. (redorbit.com)
  • Atrial fibrillation affects a larger population than ventricular tachyarrhythmias, with a prevalence of ≈0.5% in patients 50 to 59 years old, incrementing to 8.8% in patients in their 80s. (ahajournals.org)
  • They have found that atrial fibrillation in nine patients from a cohort (number not specified) referred for treatment of resistant paroxysmal atrial fibrillation was not due to the multiple reentrant wavelet hypothesis of Moe but rather to a single, rapidly discharging focus, similar to a pacemaker or a generator, that created an ECG pattern of atrial fibrillation. (ahajournals.org)
  • So my question is, is paroxysmal Atrial Fibrillation and dyspnea dangerous? (medhelp.org)
  • Minimally invasive surgical treatment of lone atrial fibrillation: early results of hybrid versus standard minimally invasive approach employing radiofrequency sources," International Journal of Cardiology , vol. 167, no. 4, pp. 1469-1475, 2013. (hindawi.com)
  • Treatment of lone atrial fibrillation: a look at the past, a view of the present and a glance at the future," European Journal Cardio-Thoracic Surgery , vol. 41, no. 6, pp. 1284-1294, 2012. (hindawi.com)
  • Hornestam B, on behalf of the Digitalis in Acute Atrial Fibrillation (DAAF) Trial Group (1997) Intravenous digoxin in acute atrial fibrillation. (springer.com)
  • Atrial fibrillation and ventricular tachyarrhythmias occurring in patients with structurally abnormal hearts are the most important arrhythmias in contemporary cardiology. (ahajournals.org)
  • The abnormal electrical impulses from these veins travel to the left atrium and then to the right atrium, causing atrial fibrillation. (bidmc.org)
  • It is important to remember, however, that there are probably different types of atrial fibrillation, even though they can have similar ECG appearances, so that this new information may not necessarily apply to all forms of atrial fibrillation. (ahajournals.org)
  • Pacemakers are useful in treating certain types of atrial fibrillation, including tachy-brady syndrome, which is characterized by intermittent atrial fibri. (reference.com)
  • A recent update of guidelines published in 2001 provides evidence-based recommendations and algorithms for managing different types of atrial fibrillation (AF). (pharmacytimes.com)
  • Electrophysiological mechanisms of atrial fibrillation. (wikimedia.org)
  • During atrial fibrillation, electrical impulses fire rapidly from multiple sites in both atria, triggering 400 or more atrial contractions per minute. (hopkinsmedicine.org)
  • In atrial fibrillation, the electrical impulses are disorganized and scattered throughout both atria. (withings.com)
  • In addition to medications, procedures also play a role in the treatment of patients with atrial fibrillation. (healthcentral.com)
  • Today there are many ways to treat and control atrial fibrillation including medications and procedures. (hrsonline.org)
  • These surgeries are only necessary if a patient has severe atrial fibrillation that has failed to respond to other treatment options, including medications and lifestyle changes. (reference.com)
  • While blood thinners (anticoagulants) are the first line treatment for reducing stroke in patients with atrial fibrillation, not everyone can safely take these medications. (einstein.edu)
  • New research links atrial fibrillation to MRI-detected brain lesions indicative of silent cerebral ischemia, similar to its link with symptomatic stroke. (medpagetoday.com)
  • Although it may not carry the inherent lethality of a ventricular tachyarrhythmia, it does have a mortality twice that of control subjects, 1 and the palpitations, hemodynamic consequences, side effects of drugs, and, most importantly, brain involvement due to thromboembolic complications make atrial fibrillation a formidable problem. (ahajournals.org)
  • He presented initially with atrial fibrillation with rapid ventricular response, a rare manifestation of Lyme carditis. (nih.gov)
  • Rapid ventricular response, or RVR, is a serious complication of atrial fibrillation and requires medical treatment, according to Healthline. (reference.com)
  • Atrial Fibrillation vs Ventricular Fibrillation: What's the Difference? (rxlist.com)
  • In contrast, ventricular fibrillation (VFib) has very short-lived signs and symptoms. (rxlist.com)
  • Laboratory studies in patients with atrial fibrillation (AF) are aimed at uncovering underlying disorders, which may be particularly important to address when ventricular rate is difficult to control. (medscape.com)
  • While not immediately fatal (as is ventricular fibrillation) AF dramatically increases the risk of stroke, elevates mortality, and diminishes quality of life. (utah.edu)
  • It seems big people with 'the highest body surface area' also have larger atriums, which increases the risk of atrial fibrillation, the authors wrote. (healthcentral.com)
  • Population-based research had suggested that every drink (12 ounces of beer, 5 ounces of wine or a 1.5 ounce of distilled spirits) increases the risk of atrial fibrillation by 8 percent. (washingtonpost.com)
  • Until recently, warfarin (approved in 1954 and marketed under the brand names Coumadin and Jantoven) had been the only drug approved for the prevention of stroke in patients with atrial fibrillation. (fda.gov)
  • Along with warfarin, a drug approved 60 years ago, these drugs are used to prevent stroke in patients with atrial fibrillation. (fda.gov)
  • 1 Strokes are more disabling in patients with atrial fibrillation and have higher 30 day mortality than those of arterial origin. (bmj.com)
  • Despite the favorable recovery of most patients, some will have their post-operative period interrupted by the development of atrial fibrillation, with a host of potential complications including stroke. (springer.com)
  • Cigarette smoking is linked to the development of atrial fibrillation, but the link with secondhand smoke exposure was unknown. (foxnews.com)
  • Atrial fibrillation may become a chronic condition. (medhelp.org)
  • Chronic atrial fibrillation occurs constantly and doesn't stop, even with treatment. (bidmc.org)
  • Other fibrillation causes may include lung disease , infection and the chronic use of stimulating substances, such as caffeine . (wisegeek.com)
  • Depending on whether one's condition is episodic or chronic, symptoms associated with atrial fibrillation may vary in intensity and presentation. (wisegeek.com)
  • Those who experience chronic signs will generally notice a gradual worsening of symptoms with the progression of the atrial fibrillation pathophysiology. (wisegeek.com)
  • Some patients with atrial fibrillation have no symptoms and are unaware of their condition until it's discovered during a physical examination, but those with symptoms may experience palpitations or sensations of a racing, irregular heartbeat, shortness of breath, chest pain or lightheadedness. (upi.com)
  • Treatment for atrial fibrillation usually improves your symptoms, such as fatigue and shortness of breath. (einstein.edu)
  • Common symptoms of uncontrolled atrial fibrillation may include shortness of breath, shortness of breath when lying flat, dizziness, and sudden onset of shortness of breath during the night. (wikipedia.org)
  • Atrial fibrillation is an irregular, rapid heartbeat. (medicalnewstoday.com)
  • In atrial fibrillation, the heartbeat is rapid and irregular. (womenshealthmag.com)
  • This represents your heartbeat in atrial fibrillation. (healthcentral.com)
  • In atrial fibrillation, the electrical flow is chaotic causing the heartbeat to become irregular and rapid. (rxlist.com)
  • For years, doctors have faced a difficult decision concerning surgery for patients with atrial fibrillation, the most common type of irregular heartbeat. (nih.gov)
  • Common genetic variants that increase the risk of atrial fibrillation can also be passed through generations in families. (medlineplus.gov)
  • Does Obesity Increase the Risk of Atrial Fibrillation? (medpagetoday.com)
  • A wealth of evidence from several different perspectives points toward obstructive sleep apnea as a significant risk factor for atrial fibrillation. (medpagetoday.com)
  • Poor sleep quality appears to be an important risk factor for atrial fibrillation, report scientists in the first study of its kind to demonstrate a relationship between poor sleep quality independent of sleep apnea and a higher risk of atrial fibrillation (AF). (elsevier.com)
  • Individuals with these variants may have a family history of atrial fibrillation, but in these cases the condition does not have a clear autosomal dominant inheritance pattern. (medlineplus.gov)
  • Having a family history of atrial fibrillation is a strong risk factor for you developing it as well. (rxlist.com)
  • The first is what we have learned about the electrophysiological mechanisms responsible for the onset of atrial fibrillation, and the second is what we know about its maintenance. (ahajournals.org)
  • As with catheter-based interventions, patients with recent onset paroxysmal (i.e., episodic) atrial fibrillation enjoy greater success rates than patients with longstanding continuous atrial fibrillation. (hopkinsmedicine.org)
  • Initial studies suggested that angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and (possibly) aldosterone antagonists might either prevent new onset and recurrent atrial fibrillation (AF) or reduce the rate of major adverse cardiovascular outcomes in these patients. (uptodate.com)
  • Overweight contributes to the onset of atrial fibrillation. (withings.com)
  • Some people have atrial fibrillation between periods of completely normal heartbeats ( intermittent or paroxysmal AF). (hopkinsmedicine.org)
  • The occurrence of paroxysmal AF (PAF), in which the fibrillation event is intermittent, resolves without medical intervention and lasts for less than seven days, adds another layer of diagnostic complication. (elsevier.com)
  • Atrial fibrillation can lead to the formation of blood clots inside the atria. (womenshealthmag.com)
  • Other blood thinners taken by mouth to prevent blood clots in atrial fibrillation, including dabigatran (Pradaxa), rivaroxaban (Xarelto) and apixaban (Eliquis), are not recommended during your pregnancy. (mayoclinic.org)
  • Some pregnant women with atrial fibrillation are prescribed injections of heparin to prevent blood clots. (mayoclinic.org)
  • If you have atrial fibrillation, you are at higher risk for blood clots and stroke. (uwhealth.org)