Atherectomy, Coronary: Percutaneous transluminal procedure for removing atheromatous plaque from the coronary arteries. Both directional (for removing focal atheromas) and rotational (for removing concentric atheromatous plaque) atherectomy devices have been used.Atherectomy: Endovascular procedure in which atheromatous plaque is excised by a cutting or rotating catheter. It differs from balloon and laser angioplasty procedures which enlarge vessels by dilation but frequently do not remove much plaque. If the plaque is removed by surgical excision under general anesthesia rather than by an endovascular procedure through a catheter, it is called ENDARTERECTOMY.Coronary Vessels: The veins and arteries of the HEART.Coronary Angiography: Radiography of the vascular system of the heart muscle after injection of a contrast medium.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Angioplasty, Balloon, Coronary: Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.Coronary Circulation: The circulation of blood through the CORONARY VESSELS of the HEART.Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Coronary Stenosis: Narrowing or constriction of a coronary artery.Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Ultrasonography, Interventional: The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.Angioplasty, Laser: A technique utilizing a laser coupled to a catheter which is used in the dilatation of occluded blood vessels. This includes laser thermal angioplasty where the laser energy heats up a metal tip, and direct laser angioplasty where the laser energy directly ablates the occlusion. One form of the latter approach uses an EXCIMER LASER which creates microscopically precise cuts without thermal injury. When laser angioplasty is performed in combination with balloon angioplasty it is called laser-assisted balloon angioplasty (ANGIOPLASTY, BALLOON, LASER-ASSISTED).Coronary Thrombosis: Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.Recurrence: The return of a sign, symptom, or disease after a remission.Angioplasty, Balloon, Laser-Assisted: Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Coronary Aneurysm: Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.Coronary Occlusion: Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.Percutaneous Coronary Intervention: A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.Angina, Unstable: Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Angioplasty, Balloon: Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.Calcinosis: Pathologic deposition of calcium salts in tissues.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Embolism: Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.Vascular Patency: The degree to which BLOOD VESSELS are not blocked or obstructed.Femoral Artery: The main artery of the thigh, a continuation of the external iliac artery.Cineangiography: Motion pictures of the passage of contrast medium through blood vessels.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.Coronary Care Units: The hospital unit in which patients with acute cardiac disorders receive intensive care.Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.Blue Toe Syndrome: A condition that is caused by recurring atheroembolism in the lower extremities. It is characterized by cyanotic discoloration of the toes, usually the first, fourth, and fifth toes. Discoloration may extend to the lateral aspect of the foot. Despite the gangrene-like appearance, blue toes may respond to conservative therapy without amputation.Saphenous Vein: The vein which drains the foot and leg.Angiography: Radiography of blood vessels after injection of a contrast medium.Hospitals, Group Practice: Hospitals organized and controlled by a group of physicians who practice together and provide each other with mutual support.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Angioscopy: Endoscopic examination, therapy or surgery performed on the interior of blood vessels.Peripheral Arterial Disease: Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.Platelet Aggregation Inhibitors: Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Popliteal Artery: The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.Plaque, Atherosclerotic: Lesions formed within the walls of ARTERIES.Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Coronary Artery Bypass, Off-Pump: Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).Lower Extremity: The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.Myocardial Revascularization: The restoration of blood supply to the myocardium. (From Dorland, 28th ed)Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Heart: The hollow, muscular organ that maintains the circulation of the blood.Peripheral Vascular Diseases: Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.Postoperative Period: The period following a surgical operation.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Clinical Enzyme Tests: Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.Limb Salvage: An alternative to amputation in patients with neoplasms, ischemia, fractures, and other limb-threatening conditions. Generally, sophisticated surgical procedures such as vascular surgery and reconstruction are used to salvage diseased limbs.Vasodilator Agents: Drugs used to cause dilation of the blood vessels.Equipment Design: Methods of creating machines and devices.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Vasodilation: The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.Tunica Intima: The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.Subclavian Steal Syndrome: A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)Retreatment: The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.Inguinal Canal: The tunnel in the lower anterior ABDOMINAL WALL through which the SPERMATIC CORD, in the male; ROUND LIGAMENT, in the female; nerves; and vessels pass. Its internal end is at the deep inguinal ring and its external end is at the superficial inguinal ring.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Counterpulsation: A technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure. It may be achieved by intra-aortic balloon, or by implanting a special pumping device in the chest, or externally by applying a negative pressure to the lower extremities during cardiac systole.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.Chest Pain: Pressure, burning, or numbness in the chest.Collateral Circulation: Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.Pulmonary Subvalvular Stenosis: Narrowing below the PULMONARY VALVE or well below it in the infundibuluar chamber where the pulmonary artery originates, usually caused by a defective VENTRICULAR SEPTUM or presence of fibrous tissues. It is characterized by restricted blood outflow from the RIGHT VENTRICLE into the PULMONARY ARTERY, exertional fatigue, DYSPNEA, and chest discomfort.Internal Mammary-Coronary Artery Anastomosis: Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Muscle, Smooth, Vascular: The nonstriated involuntary muscle tissue of blood vessels.Endothelium, Vascular: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.Adenosine: A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Drug-Eluting Stents: Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Tunica Media: The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.

The relationship between periprocedural myocardial infarction and subsequent target vessel revascularization following percutaneous coronary revascularization: insights from the EPIC trial. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications. (1/228)

OBJECTIVES: We sought to determine whether periprocedural myocardial infarction complicating percutaneous coronary revascularization is associated with subsequent clinical restenosis, as judged by the need for target vessel revascularization. BACKGROUND: Although myocardial enzyme elevation following angioplasty is associated with increased late mortality, its effect on subsequent clinical restenosis, as assessed by the need for late target vessel revascularization (TVR), is unknown. METHODS: Serial myocardial enzyme determinations were performed on 2,099 patients who underwent angioplasty or atherectomy in the Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications (EPIC) trial. Thirty-day survivors were prospectively followed for three years for adverse clinical events including death and need for TVR. RESULTS: Within the study population, periprocedural creatine kinase (CK) elevation was a predictor of late mortality. Among patients with elevated CK, however, a paradoxical decrease in the need for late TVR was present. This relationship became progressively more profound as the magnitude of CK release increased. Late TVR occurred in 29.8% of patients with no CK elevation, 24.8% with CK elevation to >3 times normal, and 16.9% with >10 times elevation (hazard ratio 0.51, 95% CI 0.29, 0.91). CONCLUSIONS: In the EPIC study, patients with periprocedural MI were less likely to develop clinical restenosis as measured by the need for TVR. Mechanistically, although it is unlikely that CK elevation prevents vascular renarrowing per se, myocardial necrosis impairs the clinical manifestation of restenosis, thereby reducing the need for ischemia-driven TVR. This novel finding 1) highlights the potential discordance between angiographic and clinical measures of restenosis, and 2) has implications for clinical trials, as therapies that reduce periprocedural MI may be associated with a perceived excess of restenosis when measured by the need for TVR.  (+info)

Influence of a platelet GPIIb/IIIa receptor antagonist on myocardial hypoperfusion during rotational atherectomy as assessed by myocardial Tc-99m sestamibi scintigraphy. (2/228)

OBJECTIVES: This study evaluated the effect of the glycoprotein IIb/IIIa (GPIIb/IIIa) antagonist abciximab on myocardial hypoperfusion during percutaneous transluminal rotational atherectomy (PTRA). BACKGROUND: PTRA may cause transient ischemia and periprocedural myocardial injury. A platelet-dependent risk of non-Q-wave infarctions after directional atherectomy has been described. The role of platelets for the incidence and severity of myocardial hypoperfusion during PTRA is unknown. METHODS: Seventy-five consecutive patients with complex lesions were studied using resting Tc-99m sestamibi single-photon emission computed tomography prior to PTRA, during, and 2 days after the procedure. The last 30 patients received periprocedural abciximab (group A) and their results were compared to the remaining 45 patients (group B). For semiquantitative analysis, myocardial perfusion in 24 left ventricular regions was expressed as percentage of maximal sestamibi uptake. RESULTS: Baseline characteristics did not differ between the groups. Transient perfusion defects were observed in 39/45 (87%) patients of group B, but only in 10/30 (33%) patients of group A (p < 0.001). Perfusion was significantly reduced during PTRA in 3.3 +/- 2.5 regions in group B compared to 1.4 +/- 2.5 regions in group A (p < 0.01). Perfusion in the region with maximal reduction during PTRA in groups B and A was 76 +/- 15% and 76 +/- 15% at baseline, decreased to 56 +/- 16% (p < 0.001) and 67 +/- 14%, respectively, during PTRA (p < 0.01 A vs. B), and returned to 76 +/- 15% and 80 +/- 13%, respectively, after PTRA. Nine patients in group B (20%) and two patients in group A (7%) had mild creatine kinase and/or troponin t elevations (p = 0.18). Patients with elevated enzymes had larger perfusion defects than did patients without myocardial injury (4.2 +/- 2.7 vs. 2.3 +/- 2.5 regions, p < 0.05). CONCLUSIONS: These data indicate that GPIIb/IIIa blockade reduces incidence, extent and severity of transient hypoperfusion during PTRA. Thus, platelet aggregation may play an important role for PTRA-induced hypoperfusion.  (+info)

Mechanisms of acute lumen gain and recurrent restenosis after rotational atherectomy of diffuse in-stent restenosis: a quantitative angiographic and intravascular ultrasound study. (3/228)

OBJECTIVES: This quantitative angiographic and intravascular ultrasound study determined the mechanisms of acute lumen enlargement and recurrent restenosis after rotational atherectomy (RA) with adjunct percutaneous transluminal coronary angioplasty in the treatment of diffuse in-stent restenosis (ISR). BACKGROUND: In-stent restenosis remains a significant clinical problem for which optimal treatment is under debate. Rotational atherectomy has become an alternative therapeutic approach for the treatment of diffuse ISR based on the concept of "tissue-debulking." METHODS: Rotational atherectomy with adjunct angioplasty of ISR was used in 45 patients with diffuse lesions. Quantitative coronary angiographic (QCA) analysis and sequential intravascular ultrasound (IVUS) measurements were performed in all patients. Forty patients (89%) underwent angiographic six-month follow-up. RESULTS: Rotational atherectomy lead to a decrease in maximal area of stenosis from 80+/-32% before intervention to 54+/-21% after RA (p < 0.0001) as a result of a significant decrease in intimal hyperplasia cross-sectional area (CSA). The minimal lumen diameter after RA remained 15+/-4% smaller than the burr diameter used, indicating acute neointimal recoil. Additional angioplasty led to a further decrease in area of stenosis to 38+/-12% due to a significant increase in stent CSA. At six-month angiographic follow-up, recurrent restenosis rate was 45%. Lesion and stent length, preinterventional diameter stenosis and amount of acute neointimal recoil were associated with a higher rate of recurrent restenosis. CONCLUSIONS: Rotational atherectomy of ISR leads to acute lumen gain by effective plaque removal. Adjunct angioplasty results in additional lumen gain by further stent expansion and tissue extrusion. Stent and lesion length, severity of ISR and acute neointimal recoil are predictors of recurrent restenosis.  (+info)

Heparin after percutaneous intervention (HAPI): a prospective multicenter randomized trial of three heparin regimens after successful coronary intervention. (4/228)

OBJECTIVES: The purpose of this study was to determine the incidence of bleeding, vascular, and ischemic complications using three different heparin regimens after successful intervention. BACKGROUND: The ideal dose and duration of heparin infusion after successful coronary intervention is unknown. METHODS: Patients were randomized to one of three heparin strategies after coronary intervention: Group 1 (n = 157 patients) received prolonged (12 to 24 h) heparin infusion followed by sheath removal; Group 2 (n = 120 patients) underwent early removal of sheaths, followed by reinstitution of heparin infusion for 12 to 18 h; Group 3 (n = 137 patients) did not receive any further heparin after intervention with early sheath removal. The primary end point of the study was the combined incidence of in-hospital bleeding and vascular events. Secondary end points included in-hospital ischemic events, length of stay, cost and one-month outcome. RESULTS: After successful coronary intervention, 414 patients were randomized. Unstable angina or postinfarction angina was present in 83% of patients before intervention. The combined incidence of bleeding and vascular events was 21% in Group 1, 14% in Group 2 and 8% in Group 3 (p = 0.01). The overall incidence of in-hospital ischemic complications was 2.2%; there were no differences between groups. Length of hospital stay was shorter (p = 0.033) and adjusted hospital cost was lower (p < 0.001) for Group 3. At 30 days, the incidence of delayed cardiac and vascular events was similar for all three groups. CONCLUSIONS: Heparin infusion after successful coronary intervention is associated with more minor bleeding and vascular injury, prolonged length of stay and increased cost. In-hospital and one-month ischemic events rarely occur after successful intervention, irrespective of heparin use. Routine postprocedure heparin is not recommended, even in patients who present with unstable ischemic syndromes.  (+info)

Low prevalence of Chlamydia pneumoniae in atherectomy specimens from patients with coronary heart disease. (5/228)

Coronary atherectomy specimens from 50 patients with coronary heart disease were examined for the presence of Chlamydia pneumoniae by two different methods of polymerase chain reaction (PCR) and by in situ hybridization. C. pneumoniae DNA was detected by PCR in atherosclerotic plaques of four patients (8%). Two patients' coronary atheromas were positive, both by a single-step 16S rRNA-based PCR and by an omp1-based nested PCR. The other two patients' specimens were positive only by the nested PCR. In contrast, C. pneumoniae was not detected by in situ hybridization in any of the cardiovascular tissues tested. Of three patients with evidence of C. pneumoniae in coronary atheromas, two had an antibody titer of 1:32 and the third had no specific antibodies detectable. Results of this study demonstrate a low prevalence of C. pneumoniae DNA in coronary atheromas. These findings do not support the hypothesis that the organism plays a major role in atherogenesis.  (+info)

In vitro examination of the safety of rotational atherectomy of side branches jailed by stents. (6/228)

In vitro experimental models of branch orifices jailed by various stents were created to estimate the safety and the efficacy of rotational atherectomy when rotational burrs were advanced through the struts of stents. The scaffolding structures of the stents were destroyed due to loss and deflection of the struts, and the size of ablated stent-particles differed: the maximal size was 1.7 mm in slotted stents, and 17.6 mm in coiled stents. Thus, there is a definite potential for ablating stents when rotational atherectomy of restenotic lesions of side-branch orifices jailed by stents is performed.  (+info)

Expression of cytokine and adhesion molecule mRNA in atherectomy specimens from patients with coronary artery disease. (7/228)

Coronary arteriosclerosis is an underlying condition in acute myocardial infarction (AMI), unstable angina pectoris (UAP) and stable angina pectoris (SAP), and is also related to restenosis (RS) following coronary intervention. To investigate the pathogenesis of this condition, a quantitative reverse transcriptase polymerase chain reaction was used to determine relative levels of mRNA for interleukin (IL)-1beta, IL-6, IL-8, transforming growth factor beta (TGF-beta), intercellular adhesion molecule (ICAM)-1, E-selectin and vascular cell adhesion molecule (VCAM)-1 using directional coronary atherectomy (DCA) specimens. Eleven patients with AMI, 7 with UAP, 10 with SAP and 6 with RS following a previous coronary intervention underwent DCA. The mRNA intensity for each molecule was expressed by comparing it with that of beta-actin mRNA. The AMI and UAP patients showed high frequencies of mRNA for IL-1beta, IL-8, TGF-beta, and ICAM-1 together with strong intensities of expression, whereas SAP patients showed decreased mRNA expression for these molecules. Increased IL-6 mRNA expression was observed only in AMI samples. Specimens from RS patients revealed an accumulated expression of proinflammatory cytokines, except for IL-6, as well as of TGF-beta. The study suggests that variation in mRNA expression may reflect the pathophysiology of specific types of coronary artery disease, and remodeling following vascular injury.  (+info)

Creatine kinase-MB elevation after coronary intervention correlates with diffuse atherosclerosis, and low-to-medium level elevation has a benign clinical course: implications for early discharge after coronary intervention. (8/228)

OBJECTIVES: The study evaluated the incidence and predictors of creatine kinase-MB isoenzyme (CK-MB) elevation after successful coronary intervention using current devices, and assessed the influence on in-hospital course and midterm survival. BACKGROUND: The CK-MB elevation after coronary intervention predominantly using balloon angioplasty correlates with late cardiac events of myocardial infarction (MI) and death. Whether CK-MB elevation after nonballoon devices is associated with an adverse short and midterm prognosis is unknown. METHODS: The incidence and predictors of CK-MB elevation after coronary intervention were prospectively studied in 1,675 consecutive patients and were followed for in-hospital events and survival. RESULTS: CK-MB elevation was detected in 313 patients (18.7%), with 1-3x in 12.8%, 3-5x in 3.5% and >5x normal in 2.4% of patients. Procedural complications or electrocardiogram changes occurred in only 49% of the CK-MB-elevation cases; CK-MB elevation was more common after nonballoon devices (19.5% vs. 11.5% after percutaneous transluminal coronary angioplasty; p < 0.01). Predictors of CK-MB elevation on multivariate analysis were diffuse coronary disease (p = 0.02), systemic atherosclerosis (p = 0.002), stent use (p = 0.04) and absence of beta-blocker therapy (p = 0.001). Adverse in-hospital cardiac events were more frequent in patients with >5x CK-MB elevation, with no significant difference between 1-5x CK-MB elevation versus normal CK-MB group. During a mean follow-up of 13 +/- 3 months, the incidence of death in the CK-MB-elevation group was 1.6% versus 1.3% in the normal CK-MB group (p = NS). CONCLUSIONS: The CK-MB elevation after coronary intervention was observed even in the absence of discernible procedural complications and was more common in patients with diffuse atherosclerosis. In-hospital clinical events requiring prolonged monitoring were higher in >5x CK-MB-elevation patients only. Midterm survival of CK-MB-elevation patients was similar to those with normal CK-MB. Our prospective analysis shows a lack of adverse in-hospital cardiac events and suggests that early discharge of stable 1-5x normal CK-MB-elevation patients after successful coronary intervention is safe.  (+info)

*Upendra Kaul

Cardiopulmonary bypass Atherectomy Coronary stenting Revascularization India portal Medicine portal "Doctor Profile". My Doc ... Rotational and Directional Atherectomy, Coronary stenting and Percutaneous Laser Myocardial Revascularization. He graduated in ... "Paclitaxel-Eluting versus Everolimus-Eluting Coronary Stents in Diabetes". N Engl J Med. 373: 1709-1719. doi:10.1056/ ...

*Atherectomy

It has also been used to treat coronary artery disease, albeit ineffectively. Atherectomy is used to treat narrowing in ... While atherectomy is usually employed to treat arteries it can be used in veins and vascular bypass grafts as well. Atherectomy ... Wasiak J, Law J, Watson P, Spinks A (December 2012). "Percutaneous transluminal rotational atherectomy for coronary artery ... Atherectomy is a minimally invasive endovascular surgery technique for removing atherosclerosis from blood vessels within the ...

*Clay Kirby

On July 19, 1991, Kirby underwent a coronary Atherectomy to open a blockage in an artery just above his heart. After the ...

*List of MeSH codes (E02)

... atherectomy MeSH E02.148.050.120.125 --- atherectomy, coronary MeSH E02.148.102.060 --- angioplasty, balloon MeSH E02.148. ... percutaneous coronary MeSH E02.148.224.165 --- catheterization, swan-ganz MeSH E02.148.442.110 --- catheter ablation MeSH ... percutaneous coronary MeSH E02.148.050.075 --- angioplasty, laser MeSH E02.148.050.075.080 --- angioplasty, balloon, laser- ...

*List of MeSH codes (E04)

... atherectomy, coronary MeSH E04.100.376.719.332 --- coronary artery bypass MeSH E04.100.376.719.332.199 --- coronary artery ... atherectomy, coronary MeSH E04.928.220.520.220 --- coronary artery bypass MeSH E04.928.220.520.220.189 --- coronary artery ... atherectomy MeSH E04.100.814.050.120.125 --- atherectomy, coronary MeSH E04.100.814.055 --- angioscopy MeSH E04.100.814.143 ... percutaneous coronary MeSH E04.100.814.050.075 --- angioplasty, laser MeSH E04.100.814.050.075.080 --- angioplasty, balloon, ...

*St. Francis Hospital (Columbus, Georgia)

For some patients, intervention such as coronary angioplasty or atherectomy may serve as possible alternatives to bypass ... Francis is awarded the Josh Nahum Award for Achievement in Infection Prevention and Control for its "Coronary Artery Bypass ... Patients choosing to have angioplasty and atherectomy are usually discharged 24-48 hours after the procedure and, in most cases ... such as coronary angiograms. Many of these tests can be performed on an outpatient basis. They serve as a helpful tool for ...

*Cutting balloon

Overview Coronary Artery Disease Treatment - Coronary Interventions ANGIOPLASTY, STENTS AND ATHERECTOMY (Cleveland Clinic) ... used in percutaneous coronary interventions. It has a special balloon tip with small blades, that are activated when the ... This procedure is different from Rotoblation (Percutaneous Transluminal Rotational Atherectomy or PCRA) whereby a diamond ... tipped device spins at high revolutions to cut away calcific (chalky) atheroma usually prior to coronary stenting. Boston ...

*Lumivascular

... and a multitude of therapeutic options for both peripheral and coronary atherosclerosis including atherectomy, angioplasty and ... investigator-initiated trial comparing intravascular ultrasound-guided atherectomy to angiography guided atherectomy in ... A lumivascular approach is valuable for peripheral arterial CTO crossing and future applications could likely improve coronary ... Histopathologic evidence of adventitial cuts predicts restenosis after directional atherectomy of lower extremity peripheral ...

*Drug-eluting stent

coronary-artery bypass grafting in multivessel coronary disease". N. Engl. J. Med. 358 (4): 331-41. doi:10.1056/NEJMoa071804. ... including balloon angioplasty and atherectomy. Drug-eluting stents (DES) have also been extensively studied, and are generally ... Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left ... A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary ...

*Percutaneous coronary intervention

Implantation of stents Rotational or laser atherectomy Brachytherapy (use of radioactive source to inhibit restenosis) The ... Percutaneous coronary intervention (PCI) is a non-surgical procedure used to treat narrowing (stenosis) of the coronary ... Coronary angioplasty, also known as percutaneous transluminal coronary angioplasty (PTCA), because it is done through the skin ... 2012). "Percutaneous coronary intervention versus optimal medical therapy in stable coronary artery disease: a systematic ...

*Angioplasty

A percutaneous coronary intervention is first performed. A PCI used with stable coronary artery disease reduces chest pain, but ... Often, peripheral angioplasty is used in conjunction with guide wire, peripheral stenting and an atherectomy. Carotid artery ... coronary arteries of the heart found in coronary heart disease. These stenotic segments are due to the buildup of cholesterol- ... The first coronary angioplasty with a drug delivery stents system was performed by Luis de la Fuente, at de Instituto Argentino ...

*Outline of cardiology

Coronary artery disease (CAD)- Coronary artery disease is a general term for any reduction in coronary circulation. One such ... It is a form of PCI and generally what is implied when referring to "PCI." Atherectomy - Enlarging the lumen of an artery by ... Coronary artery bypass surgery (CABG): Grafting an artery or vein from elsewhere to bypass a stenotic coronary artery. ... Percutaneous coronary intervention (PCI) - Procedures to treat stenotic coronary arteries by accessing through a blood vessel. ...

*Peripheral artery disease

Atherectomy, in which the plaque is scraped off of the inside of the vessel wall (albeit with no better results than ... PAD carries a greater than "20% risk of a coronary event in 10 years". There is a low risk that an individual with claudication ... When narrowing occurs in the heart, it is called coronary artery disease, while, in the brain, it is called cerebrovascular ... Any flow limiting stenoses found in the x-ray can be identified and treated by atherectomy, angioplasty or stenting. Contrast ...

*Ashok Seth

He is the first cardiologist in the region to perform an angioscopy and directional atherectomy. He is reported to be the first ... Chandra P, Cribier A, Seth A (1995). "Utility of Pilot wire in angioplasty of tortuous and highly angulated coronary arteries ... Chandra P, Cribier A, Seth A (1995). "Utility of Pilot wire in angioplasty of tortuous and highly angulated coronary arteries ... Atherectomy Drug Eluting Stents Ventricular assist device Angioscopy Embolectomy Transmyocardial revascularization India portal ...

*ICD-9-CM Volume 3

Removal of coronary artery obstruction and insertion of stent(s) (36.1) Bypass anastomosis for heart revascularization (36.2) ... Percutaneous angioplasty or atherectomy of precerebral (extracranial) vessel(s) (01) Incision and excision of skull, brain, and ...
Atherectomy led to better postprocedural luminal dimensions but was similar to angioplasty for 6-month outcomes in left anterior descending coronary arteries. Coronary atherectomy, endoluminal stenting, and laser angioplasty are alternative interventions to balloon angioplasty (PTCA) for the percutaneous revascularization of obstructive CAD. They were developed because of the persistent unacceptably high restenosis rate (30% to 50%) associated with PTCA. The Coronary Angioplasty versus Excisional Atherectomy Trial (CAVEAT) by Topol and colleagues and the Canadian Coronary Atherectomy Trial (CCAT) by Adelman and colleagues are important because they are the first randomized trials to compare PTCA with an alternative intervention device. In fact, only 2 other randomized trials with PTCA have been reported: the Angioplasty Compared to Medicine (ACME) trial in patients with single-vessel disease and the Randomized Intervention Treatment of Angina (RITA) trial comparing PTCA with bypass graft ...
Directional atherectomy was associated with a trend toward lower rates of restenosis at 6 months, and increased mortality and ischemic events at one year. DCA resulted in higher rates of early complications at a higher cost and with no clinical benefit. Paradoxically, initial dissemination of these study results produced a transient increase in use of directional atherectomy at CAVEAT-I sites. Among investigators in the trial, there may have been a lack of influence of trial data on clinical practice patterns 1 year after publication of the results.. ...
View details of top coronary atherectomy hospitals in Chennai. Get guidance from medical experts to select best coronary atherectomy hospital in Chennai
In addition to compressing and reshaping atheroma, atherectomy excises tissue and debulks plaques; it was anticipated that this mechanism would result in a lower rate of restenosis than that occurring after angioplasty. These expectations were not fulfilled in this trial. Although the procedural success rate was somewhat higher and the postprocedure lumen larger in patients treated with atherectomy, lumen dimensions, restenosis rates and clinical outcomes were similar in the two groups at six months. Clinical outcomes for the two groups were similar at up to 18 months after the procedure.. ...
Atherectomy is a minimally invasive endovascular surgery technique for removing atherosclerosis from blood vessels within the body. It is an alternative to angioplasty for the treatment of peripheral artery disease, but the studies that exist are not adequate to determine if it is superior to angioplasty. It has also been used to treat coronary artery disease, albeit ineffectively. Atherectomy is used to treat narrowing in arteries caused by peripheral artery disease. Unlike angioplasty and stents, which push plaque into the vessel wall, atherectomy cuts plaque from the wall of the artery. While atherectomy is usually employed to treat arteries it can be used in veins and vascular bypass grafts as well. Atherectomy falls under the general category of percutaneous revascularization, which implies re-canalizing blocked vasculature via a needle puncture in the skin. The most common access point is near the groin through the common femoral artery (CFA). Other common places are the brachial artery, ...
Rotational atherectomy by rotablator. The rotablator pulverize the calcified plaque of atheroma. Here, example of a coronary artery. - Stock Image C002/7142
BACKGROUND: There is paucity of data regarding the clinical outcome of second generation drug- eluting stents (DES) post rotational atherectomy (RA) for heavily calcified coronary lesions (HCCL). METHODOLOGY: The study cohort comprised 99 (116 lesions) consecutive patients who underwent RA for HCCL at our institution and received either a first generation DES (40 patients, 53 lesions) or a second generation DES (59 patients, 63 lesions). The analyzed clinical parameters were the 12-month rates of death (all cause and cardiac), Q-wave MI, target lesion revascularization (TLR), definite stent thrombosis (ST) and major adverse cardiac events (MACE) defined as the composite of death, Q-wave MI, or TLR. RESULTS: The two groups were well matched for their baseline characteristics except for a lower left ventricular ejection fraction in the second generation DES group (46.0±23.0% vs. 55.0±9.0%; p=0.02). The group receiving second generation DES had more type C lesions (81.0% vs. 58.8%; p=0.01), ...
Background: C reactive protein (CRP), an important serum marker of atherosclerotic vascular disease, has recently been reported to be active inside human atherosclerotic plaques.. Aims: To investigate the simultaneous presence of macrophages, CRP, membrane attack complex C5b-9 (MAC), and oxidised low density lipoprotein (oxLDL) in atherectomy specimens from patients with different coronary syndromes.. Methods: In total, 54 patients with stable angina (SA; n = 21), unstable angina (UA; n = 15), and myocardial infarction (MI; n = 18) underwent directional coronary atherectomy for coronary lesions. Cryostat sections of atherosclerotic plaques were immunohistochemically stained with monoclonal antibodies: anti-CD68 (macrophages), anti-5G4 (CRP), aE11 (MAC), and 12E7 (oxLDL). Immunopositive areas were evaluated in relation to fibrous and neointima tissues, atheroma, and media. Quantitative analysis was performed using image cytometry with systematic random sampling (percentage immunopositive/total ...
左主幹部をplatformとするpercutaneous transluminal coronary rotational atherectomyの検討 Procedural Results and 3-Month Outcome of Percutaneous Transluminal Coronary Rotational Atherectomy Requiring the Activation of the Burr in the Left Main Coronary Artery ...
Objectives. The purpose of this study was to examine the proliferative capacity and extracellular matrix synthesis of human coronary plaque cells in vitro.. Background. Common to both primary atherosclerosis and restenosis are vascular smooth muscle cell proliferation and production of extracellular matrix proteins. The applicability to humans of experimental animal models of these processes has been questioned.. Methods. Primary atherosclerotic and restenotic lesions were excised by percutaneous directional coronary atherectomy in 93 patients. Smooth muscle cells were cultivated by an explant technique and identified by their morphology in culture, ultrastructural features under electron microscopy and immunostaining using monoclonal antibodies to smooth muscle cell alpha-actin. Proliferation in secondary culture was assessed with growth curves and the synthesis of collagen and sulfated glycosaminoglycans by the incorporation of 3H-proline and 35S-sulfate, respectively. These studies were also ...
TY - GEN. T1 - Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device. AU - Lovik, Ryan D.. AU - Abraham, John P.. AU - Sparrow, Ephraim M. PY - 2009/12/1. Y1 - 2009/12/1. N2 - In vitro and cadaver experiments, coupled with numerical simulations, were performed to assess the possibility mat orbital atherectomy might cause thermal damage of tissue. The experiments involved debulking operations on a surrogate artery and on the plaque-lined posterior tibial artery of a cadaver. Temperatures and coolant flow rates measured during these experiments enabled a numerical simulation of the debulking of a plaque-lined artery in a living human. The temperature variations from the numerical simulations were used to evaluate a thermal injury index. The resulting values of the index were found to be several orders of magnitude below the threshold value for thermal injury. It is concluded that it is extremely unlikely that the use of an orbital debulking ...
Arteriogram and Atherectomy Baltimore, MD - Minimally Invasive Vascular Center offers Arteriogram and Atherectomy services. Our practice serves Baltimore, MD, Laurel, MD, Silver Spring, MD and the surrounding areas.
Leading interventional cardiologists at The Mount Sinai Hospital are the first in the world to use a newly U.S. Food and Drug Administration (FDA) approveddevicefor the treatment of severely calcified coronary arteries before the placement of a cardiac stent to open a blocked artery.. The new device being used in the Cardiac Catheterization Laboratory at The Mount Sinai Hospital is called the Diamondback 360® Coronary Orbital Atherectomy System. Its spinning electrically powered 1.25 mm diamond-coated crown is located on a thin cardiac catheterization guide wire and works within seconds to reduce the amount of hard calcium buildup in a coronary artery. The small calcium particles sanded from the arterys wall are then naturally discarded from the heart and the body.. The atherectomy system made by Cardiovascular Systems, Inc. was just FDA approved on Oct. 21. It is the first new coronary atherectomy system in more than two decades.. "We are excited that we are the first in the world to offer ...
An elongate tubular body extends between a rotatable cutter and a control. The cutter is connected to the control with a rotatable element and has a serrated surface. A vacuum is applied through an annular passage defined between the tubular body and the rotatable element. The control has an indicator that reveals resistance to rotation and/or reduction in flow. Material that has been processed by the cutter is aspirated through the tubular body for disposal. The control enables rotation of the rotatable element only following application of a predetermined level of vacuum.
Boston Scientifics Jetstream atherectomy system has received CE mark for a new in-stent restenosis indication. This indication gives EU physicians "another safe and effective treatment option for in-stent restenosis, a disease state that has historically been challenging to treat with traditional therapies," says a Boston Scientific press release.. The indication is supported by data from the Jetstream-ISR feasibility study, in which the device demonstrated a strong safety profile, with zero device-stent interactions. The study included long, complex lesions (62% were TASC C&D). Six-month freedom from target lesion revascularisation was 86.2% with patency at 72%.. ...
cleared coronary balloon on the market-is critical for physicians treating highly complex coronary lesions. As the market leader in coronary atherectomy, the 1.0mm balloon complements our orbital atherectomy system as we continue providing advanced solutions for treating the complex and high-risk indicated patient." At launch, CSI will offer both the 1.0-4.0mm Sapphire II PRO and the 2.0-4.0mm Sapphire® NC Plus non-compliant coronary balloons on a limited basis. The company anticipates that OrbusNeichs full balloon product portfolio will become available in the U.S. throughout 2018 and 2019. About OrbusNeich OrbusNeich is a global pioneer in the provision of life-changing vascular solutions and offers an extensive portfolio of products that set industry benchmarks in vascular intervention. Current products include the worlds first dual therapy stents, the COMBO Plus and COMBO Dual Therapy Stents, together with stents and balloons marketed under the names of Azule®, Scoreflex®, Sapphire® ...
Endovascular Today sat down with a multidisciplinary panel of esteemed interventionists to discuss their current practice paradigms for atherectomy, including the hot topic of Vessel Prep prior to drug-coated balloons and other adjunctive therapies.
Ease of use has dictated the destiny of all new techniques and devices in interventional cardiology. The popularity of stents began when they became as easy to use and more predictable than balloons. Conversely, directional and rotational atherectomy fell into oblivion or became confined to a small niche application. Some of these devices have been underused, even when proved beneficial, such as filters in saphenous vein graft treatment or thrombectomy in acute myocardial infarction. For chronic total occlusions (CTOs), the only route to success passes through the use of multiple dedicated wires, guided by contralateral injection, and of over-the-wire (OTW) balloons or microcatheters, sometimes inserted retrogradely via collateral vessels with the use of devices with exotic names like Tornus and Corsair (Asahi Intecc, Nagoya, Japan).. No wonder few interventionalists have ventured into this uncharted territory. The problem is, however, that CTOs are very frequent and are present in ,30% of ...
Introduction Rotational atherectomy (RA) during primary PCI (PPCI) for STEMI is relatively contraindicated because of the perceived increased risk of no-reflow. However, RA PPCI may sometimes be required to restore flow in heavily calcified coronary arteries. Previously only very limited observational data has described the use of RA in PPCI. Aim We report the clinical and procedural characteristics, and in hospital outcomes, of 21 patients who underwent RA PPCI at our centre between 2006 and 2016,. Methods A retrospective review of the PCI database and medical records.. Results 21 patients (age 78(10) years (mean (SD)), 12 men) underwent RA during PPCI (0.4% of all PPCI). 3 patients had cardiogenic shock at presentation and 2 had out of hospital cardiac arrest. Hypertension (n=19), smoking history (n=18), hypercholesterolemia (n=16), diabetes (n=6) and chronic kidney disease (n=6 with eGFR ,60) were frequently present. Aspirin was given to 20/21 patients and clopidogrel, ticagrelor and ...
Coronary lesions with severe (or heavy) calcification are classified as complex lesions and are known to carry lower success rates and higher complication rates following percutaneous coronary intervention. The Diamondback 360(®) Coronary Orbital At
Stents have emerged as one of the major therapeutic tools for percutaneous intracoronary revascularization procedures. In fact, a stent is implanted in at least 30% of lesions attempted. Their clinical impact is huge because stenting has produced a decrease int the need for emergency surgery to 0.5%, with an incidence of acute myocardial infarction related to angioplasty of 2% and a death rate of , 1% despite unfavourable clinical and anatomical conditions treated. The initial price of stenting was a high frequency of subacute stent thrombosis and peripheral vascular complications, which has been solved ...
EMEA (Europe, Middle East, Africa). In July 2018, Cardiovascular Systems, Inc. (CSI®) announced that OrbusNeich Medical Co. Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems outside the United States and Japan.. Medikit Co., Ltd:. →Japan. In November 2016, Cardiovascular Systems, Inc. (CSI®) announced that Medikit, Co., Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan.. ...
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Looking for online definition of coronary atherectomy in the Medical Dictionary? coronary atherectomy explanation free. What is coronary atherectomy? Meaning of coronary atherectomy medical term. What does coronary atherectomy mean?
Medtronic has been granted CE mark approval for the HawkOne directional atherectomy system in a lower profile size for treating patients with peripheral artery disease. The new HawkOne 6 Fr provides an effective and easy-to-use treatment option for patients with peripheral artery disease both above and below the knee with a single device. The HawkOne system is designed to remove plaque from the vessel wall and restore blood flow.. "Directional atherectomy is an established treatment modality for patients with complex peripheral artery disease to restore patency, maximise luminal gain and preserve future treatment options," says Thomas Zeller, head, Department of Angiology, Universitäts-Herzzentrum Freiburg, Bad Krozingen, Germany. "The new smaller HawkOne 6Fr size is an advanced option to treat patients with multi-level peripheral artery disease, addressing lesions of various length, morphology, and location, particularly those below the knee.". The HawkOne system is also designed to enable ...
However, being able to visualize the vessel with the lumivascular technology is clearly appealing and suggestive of safe passage. Distal embolization remains a major concern (especially atherectomy for ISR), and questions the need for embolic protection every time (filter was used only in 22% of patients in the DEFINITVE LE trial).7 Unprecedented complications can arise, which require expertise and catheter skills and may lead to the possibility of open vascular surgery in these high-risk patients.. DA in ISR lesions have been contraindicated due to the potential risk of cutter entrapment on stent struts during atherectomy. However, with the advent of concurrent imaging during DA, this risk can potentially be avoided. Nevertheless, as seen in this case, despite adequate visualization with OCT imaging, there can be significantly malapposed stent struts in overlapped segments that may still pose a risk for trapping the DA catheter. In such scenarios, the use of adjunctive balloon angioplasty ...
A rotational atherectomy device for removing a stenotic tissue from a vessel of a patient is disclosed. The device comprises a rotatable, flexible, hollow drive shaft having a fluid impermeable wall defining a fluid impermeable lumen of the drive shaft and, an abrasive element mounted to a distal end portion of the drive shaft proximal to and spaced away from a distal support element formed at a distal end of the drive shaft, the distal support element being inflatable by pressurized fluid which flows in an antegrade direction through said lumen of the drive shaft and is at least partially re-directed into the distal fluid inflatable support element. The distal fluid inflatable support element has an outer wall comprising an outflow opening located such that said outflow opening faces an inner surface of a treated vessel during rotation of the drive shaft so that a flow of fluid through said outflow opening forms a layer of fluid between the outer wall of the rotating fluid inflated distal support
An atherectomy device is used for removing a restriction in a blood vessel. The atherectomy device includes a cutting portion having a lumen therein, the lumen being sized to track over a guidewire, wherein an outer surface of the cutting portion comprises a cutting surface. An elongate shaping member is cooperable with the cutting portion and is disposed generally longitudinally relative to the cutting portion. The shaping member has an insertion conformation and an expanded conformation. The expanded conformation is radially expanded relative to the insertion conformation. The shaping member is configured to deform the cutting portion from an insertion shape into a cutting shape as the shaping member moves from the insertion conformation to the expanded conformation. A drive shaft is coupled to a proximal end of the cutting portion and is configured to be rotationally driven.
The global Orbital Atherectomy Device Market report provides an accurate investigation of the different patterns and parameters affecting the industrial growth of the Orbital Atherectomy Device market at a global level. An assessment of the effect of the current situation and trends in the market is additionally included to provide an overview of the markets future position. The report provides the detailed information related to the global Orbital Atherectomy Device market dynamics and demonstrates superior forecast for the development of the market and its key competitors Medtronic (Ireland), Philips (Netherlands), Boston Scientific (US), Cardiovascular Systems (US), Straub Medical (Switzerland), BIOTRONIK (Netherlands), C.R. Bard (US), Avinger (US) based on consistent information.. Apply here for the sample copy of the report @: www.99strategy.biz/request-for-sample.html?repid=46491. Furthermore, The report presents a detailed segmentation Peripheral Vascular, Cardiovascular, ...
The incidence of coronary artery disease requiring coronary intervention in patients with Kawasaki disease is high. Because coronary artery lesions in Kawasaki disease commonly involve severe calcification and aneurysmal changes which can progress with time, in contrast with adult atherosclerotic coronary artery lesions, the indication or technique of catheter intervention for adult patients cannot be directly applied. However, the experience of coronary intervention in Kawasaki disease is extremely limited compared to that with intervention in adults, which provides satisfactory therapeutic results. There are several kinds of percutaneous coronary intervention techniques in Kawasaki disease including balloon angioplasty, stent implantation, rotational ablation, and directional coronary atherectomy. Satisfactory acute results for coronary balloon angioplasty can be obtained in patients in a relatively short interval from the onset of disease, especially within 6 years. However, the incidence of ...
This medical exhibit illustrates the Atherectomy Procedure. The atherectomy instrument is visualized within the coronary artery shaving away the atherosclerotic plaque .
An atherectomy apparatus and method is disclosed for the purpose of surgical excision of atheromas which typically consist of plaque deposits that cause narrowing (stenosis) of an artery. The apparatus, called a pullback atherectomy catheter, cuts and collects obstructive material into a collection chamber as the catheter is pulled back through obstructive material within a human vessel such as an artery.
The Global Atherectomy Devices Market is expected to reach USD 894.69 million by 2025, based on a new report by Hexa Reports. The demand for atherectomy de
Data are mean value ± SD, unless otherwise indicated. ANOVA = analysis of variance; CSA = cross-sectional area; EEM = external elastic membrane; P+M = plaque plus media; Δ = change in.. ...
Figure 1 Coronary Angiogram and Intravascular Ultrasound Images of the Left Coronary System. (A) Pre-procedural angiogram demonstrating a restenosed 3.5 × 15-mm Palmaz-Schatz stent (Cordis, Johnson & Johnson Company, Warren, New Jersey) (dotted line) implanted 20 years ago on the proximal LAD and a long segment of calcified disease extending from the LMS to the distal LAD, with involvement of the LAD/diagonal bifurcation (arrows). (B) Angiogram after rotational atherectomy with 1.5-mm burr and aggressive pre-dilation with 3.0- to 3.5-mm noncompliant balloons on LAD. A 2.25 × 12-mm EES in the diagonal ostium with crushed protruding EES struts (dotted line). (C) Intravascular ultrasound showing lumen area of 3.2 mm2 with a vessel diameter of 4.8 mm at the distal LMS. (D) Palmaz-Schatz stent struts (arrowheads) with evident dissection in the restenosed segment (arrows). (E) Cracked napkin-ring calcification after rotational atherectomy and pre-dilation (arrows). (F) Crushed EES struts on to the ...
ECCENTRIC ABRADING HEAD FOR HIGH-SPEED ROTATIONAL ATHERECTOMY DEVICES - The invention provides a rotational atherectomy device having, in various embodiments, a flexible, elongated, rotatable drive shaft with at least one flexible eccentric enlarged abrading head attached thereto. In other embodiments, the eccentric abrading head is not flexible or partially flexible. At least part of the eccentric enlarged cutting head has a tissue removing surface-typically an abrasive surface. In certain embodiments, the abrading head will be at least partially hollow. When placed within an artery against stenotic tissue and rotated at sufficiently high speeds the eccentric nature of the enlarged cutting head causes the cutting head and drive shaft to rotate in such a fashion as to open the stenotic lesion to a diameter substantially larger than the outer diameter of the enlarged cutting head. Preferably the eccentric enlarged cutting head has a center of mass spaced radially from the rotational axis of the ...
A vascular catheter includes a flexible catheter body having proximal and distal ends and an elongate housing secured to the distal end of the catheter body. An interactional device is disposed on one side of the housing, and at least two spaced-apart inflatable chambers are located on the other side of the housing generally at its proximal and distal ends, respectively. The inflatable chambers may be expanded simultaneously or separately, and the spaced-apart positioning of the chambers provides for stable positioning of the housing during atherectomy procedures, imaging procedures, and the like. The balloon is conveniently connected to the housing by an integral flange structure which is secured through an inflation aperture on the housing side. The balloon may be inflated through an annular inflation which is defined by a separate isolation tube disposed in the central lumen of the catheter body.
An atherectomy system for cutting, ingesting and removing an obstruction from within a patients artery, comprising a flexible guide-wire insertable into the artery, a flexible rotary-catheter rotatably disposed and slidable over the flexible guide-wire, a blade forming a distal end of the flexible rotary-catheter having teeth on its periphery which are bent inward, a continuous passage for ingesting the cut obstruction material between the flexible rotary-catheter and the flexible guide-wire, means at the proximal end of the flexible rotary-catheter for rotating it and positive displacement pump means connected to the continuous passage to pull the cut obstruction material proximally.
Press release - Market Expertz - Atherectomy Devices Market Size, Share Growth, Trends, Devices, Applications, Competitive Analysis, Industry Expansion Strategies, By 2027 - published on openPR.com
Disclosed is a device for delivering tissue adhesives and/or sealant patches to a surface which covers or surrounds a lumen, cavity or organ, or potential lumen or cavity, within a human or other animal. Also disclosed is a method of delivering tissue adhesives and/or sealant patches to a surface which covers or surrounds a lumen, cavity or organ, or potential lumen or cavity. The method is particularly suited to sealing perforations in vascular walls, such as after arterial access for Percutaneous Transluminal Coronary Angioplasty (PTCA), Percutaneous Coronary Angiography and Percutaneous Coronary Atherectomy and similar diagnostic and therapeutic procedures.
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Despite advances in experience and equipment, CTO recanalization with the use of contemporary guidewires and techniques may still be unsuccessful in ≥25% of cases. Numerous devices have been developed to approach such refractory and complex cases. Many of these devices never progressed beyond the investigational phase because their use in small numbers of patients demonstrated either excessively high rates of complications (typically either dissection and/or perforation) or success rates not clearly greater than those achieved by standard equipment. Examples of failed CTO devices include the Magnum/Magnarail system,38,39 the Kensey Catheter,40 the ROTACS Low Speed Rotational Atherectomy Catheter,41 and the Excimer Laser Wire.42. Two devices specifically designed for refractory CTO recanalization have demonstrated sufficient safety and efficacy to have received approval by the Food and Drug Administration for sale in the United States: the Safe Cross-RF guidewire and the Frontrunner catheter. ...
48 hours postoperatively. One case remained after hospital discharge with monoplegia and dyslalia. One patient had peripheral vascular complications at the site of arterial cannulation with thrombosis, which required embolectomy and raffia with a bovine pericardial patch at the second day after surgery. These complications occurred only in cases of aortic valve replacement in patients with severe stenosis and calcification of annulus and leaflets.. One patient underwent reoperation for mitral stenosis, pulmonary hemorrhage on the fourth postoperative day, after discharge from the ICU and was managed, again in the ICU, with mechanical ventilation. Another patient had pulmonary hemorrhage on discharge from the operating room, probably secondary to complications of selective cannulation, which occurred at 3rd postoperative day. Five (4.8%) patients underwent reoperation for bleeding, all through smaller incisions, only with the help of videoendoscopy.. Five patients, all of the group GcCPB, died ...
A technique for ablation and removal of plaque deposits from the arterial, venous, vascular graft or other tissue wall of a patient. Ablation is accomplished by directing a high pressure jet of sterile saline solution at the plaque deposit. The high pressure jet is located at the distal end of a catheter which is advanced through the vascular system to the site of the plaque deposit. Removal of the debris is via an evacuation lumen within the catheter. The arterial wall is protected from damage by the catheter design which directs the high pressure jet towards a portion of the distal end of the catheter which serves as a target. The distal end of the catheter is placed such that the plaque or other deposit to be ablated is positioned between the high pressure jet and the target. An optional ultrasonic transducer array located adjacent the high pressure jet and the evacuation lumen permits the attending physician to monitor the procedure. A balloon may be used to hold the catheter against the deposit
An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the di
EMEA (Europe, Middle East, Africa). In July 2018, Cardiovascular Systems, Inc. (CSI®) announced that OrbusNeich Medical Co. Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems outside the United States and Japan.. Medikit Co., Ltd:. →Japan. In November 2016, Cardiovascular Systems, Inc. (CSI®) announced that Medikit, Co., Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan.. ...
Rex Medical of Conshohocken, Pennsylvania won regulatory approval from the FDA to sell its Cleaner Rotational Thrombectomy System. The atherectomy system
It looks like a miniature football and spins faster than one of Randall Cunninghams tosses -- up to 190,000 revolutions per minute.But then the device, a new surgical tool called a Rotablator, must
DISCONTINUED BY MANUFACTURER OR DISCONTINUED PRODUCT. FOR YOUR INFORMATION PURPOSES, WE HAVE KEPT THIS ITEM PLACEMENT AS COURTESY TO OUR CUSTOMERSYou may...
nice guy, but seems to have an unstable disposition to the point that I would not do business with him or recommend that others do so. I dont think hes dishonest, and this rating is not set in stone. If I (passively) observe positive changes in his behavior, this rating will improve. For now, caveat creditor ...
[96 Pages Report] Check for Discount on United States Laser Atherectomy Devices Market Report 2017 report by QYResearch Group. In this report, the United States Laser Atherectomy Devices market...
An atherectomy catheter is provided having a tissue collection chamber capable of being cleaned out in a simple, fast and effective way, and also provides methods of using said catheter to remove material from a blood vessel lumen. In one embodiment the tissue collection chamber has an expandable tip having a first closed position capable of retaining material in the chamber and having a second open position that may allow expulsion of material from the chamber. In a second embodiment the tissue collection chamber has a displaceable tip having a first closed position to retain material in the chamber and having a second open position to allow expulsion of material from the chamber.
The report focuses on United States major leading industry players providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis is also carried out. The Atherectomy and Thrombectomy industry development trends and marketing channels are analyzed. Finally the feasibility of new investment projects are assessed and overall research conclusions offered ...
Expertise, Disease and Conditions: Acute Myocardial Infarction (AMI), Cardiac Catheterization, Cardiovascular Diseases, Cardiovascular Interventions, Carotid Artery Disease, Carotid Artery Stenosis, Carotid Artery Stenting, Chronic Total Coronary Occlusion, Chronic Total Occlusions, Circulatory Support Devices, Coronary Angiography, Coronary Artery Disease, Coronary Artery Stenting, Coronary Care Unit, Emboli-Protection Devices, Endovascular Therapies, Fractional Flow Reserve, Heart Disease, Hypertension, Interventional Cardiology, Intravascular Ultrasound (IVUS), Invasive Cardiology, Laser Atherectomy, Lower Extremity Revascularization, Pericardiocentesis, Peripheral Angiography, Peripheral Arterial Disease (PAD), Peripheral Vascular Disease, Renal Artery Disease, Restenosis, Rotational Atherectomy, Trans-Radial Intervention, Valvular Heart Disease, Valvuloplasty for Valvular ...
This study detected DNA from HCMV in most coronary atherosclerotic lesions and indicated that concurrent infection with EBV-1 is also frequent. The high incidence of HCMV in coronary arteries wall of patients suffering from atherosclerosis has also been reported by Hendrix et al. (15), although Shi & Tokunaga (18) detected HCMV in 40% of atherosclerotic aortic tissue. In our study, 50% of the coronary artery atheromas were positive to EBV-1. HCMV DNA in atherosclerotic tissue was reported for the first time by Shi & Tokunaga (18) in 8 out of 10 atherosclerotic aortic tissues from autopsies. Most studies implicate HCMV infection with greater risk of accelerated atherosclerosis following heart transplantation (12) and restenosis following coronary atherectomy (22). Grahame-Clarke et al. (11) showed that relatively young asymptomatic individuals seropositive for HCMV have abnormal vascular reactivity consistent with endothelial dysfunction. Their results also suggest that previous HCMV infection ...
A system and method for opening a lumen in an occluded blood vessel, e.g., a coronary bypass graft, of a living being. The system comprises an atherectomy catheter having a working head, e.g., a rotary impacting impeller, and a debris extraction sub-system. The atherectomy catheter is located within a guide catheter. The working head is arranged to operate on, e.g., impact, the occlusive material in the occluded vessel to open a lumen therein, whereupon some debris may be produced. The debris extraction sub-system introduces an infusate liquid at a first flow rate adjacent the working head and withdraws that liquid and some blood at a second and higher flow rate, through the guide catheter to create a differential flow adjacent the working head, whereupon the debris is withdrawn in the infusate liquid and blood for collection outside the beings body. The introduction of the infusate liquid may also be used to establish an unbalanced flow adjacent the working head to enable the atherectomy catheter to
Drug-coated balloon (DCB) angioplasty of femoropopliteal TASC II A and B (Trans Atlantic interSociety Consensus conference) lesions has shown promising mid-term results in randomised controlled trials.1-4 However, depending on lesion complexity, bail-out stent placement is indicated in a significant percentage of interventions and patency fai
Aortic & Peripheral Vascular net sales for the three and six months ended October 27, 2017 were $452 million and $891 million, respectively, an increase of 5 percent and 4 percent, respectively, as compared to the corresponding periods in the prior fiscal year. Aortic & Peripheral Vascular net sales growth for the three and six months ended October 27, 2017 was driven by strong performance in drug-coated balloons and success of the Endurant IIs aortic stent graft, as well as success of the Heli-FX EndoAnchor System. For the three months ended October 27, 2017, net sales growth was also driven by Percutaneous Transluminal Angioplasty (PTA) balloons and the recent launch of Concento 3D detachable coil system, as well as the Valiant Captiva thorasic stent graft systems. Continued strong adoption of the HawkOne 6 French directional atherectomy system also contributed to net sales growth for the three and six months ended October 27, 2017. ...
A catheter is disclosed which is capable of cutting obstructive tissue from a vessel of a living body while shielding a portion of the wall of the vessel from being exposed to the cutting blade at the catheters distal end. An essentially continuous outer surface at the catheters distal end allows it to be readily advanced through an introducer sheath and through a tight stenosis in an artery. The shield at the catheters distal end could subtend an arc from as little as 45 degrees to as large as 270 degrees depending on the extent of the vessel wall that is to be protected from being cut. A vacuum source at the catheters proximal end can cause a suction to exist at a cutout at the catheters distal end in order to pull obstructive tissue into the cutout as the cutting cylinder is pulled back in a retrograde direction, this suction being capable of enhancing the removal of the obstructive tissue.
A cylindrical housing has a plurality of seriate slots. A helical cutter is rotatably mounted within the housing. A drive wire passes through the housing and connects with the cutter to provide rotational movement to the cutter. Plaque is caught between the slots and the blades of the rotating cutter, cut away from the arterial wall, ground up and flushed out through a catheter.
We treat Peripheral arterial disease with minimally invasive state of the art tools. Often at times patients are treated by surgical bypass when they suffer from blockages in the legs. However we use tools such as CSI atherectomy, SilverHawk atherectomy devices for opening up these blocked vessels ...
This is a prospective, single-arm, multi-center study to evaluate the safety and performance of the OAS in treating de novo, severely calcified coronary lesions in adult subjects. Study is going to enroll up to 429 subjects in up to 50 U.S. study sites. The primary safety endpoint is 30-day MACE and primary efficacy endpoint is procedural success. All subjects will be treated with the orbital atherectomy system and adjunctive stent. All subjects will be followed in clinic at 30 days. Additionally, all subjects will have an annual phone call or clinical follow up at each anniversary until study is closed ...
In this study we hypothesized that there is any association between certain single polymorphisms in the genes encoding interferon- gamma (IFNG A874T) and its two receptor subunits (IFNGR1 C-56T and IFNGR2 A839G) and restenosis and other adverse events following coronary stenting. A previous study from our institution (Zohlnhöfer et al., 2001) analysed the expression of 2435 genes in atherectomy specimens derived from restenotic lesions following coronary stent implantation- with the result of 223 differentially expressed genes compared to controll specimens. 37 of these genes indicated activation of IFN- gamma signalling in neointimal smooth muscle cells. The significance of the studied polymorphisms was evaluated in a cohort study that comprised 2591 consecutive patients with symptomatic coronary artery disease who underwent coronary angiography and stent implantation at Deutsches Herzzentrum and 1. medizinische Klinik, Klinikum rechts der Isar, Munich. Follow-up angiography was routinely ...
COLORADO SPRINGS, Colo., June 4, 2014-- A presentation by principal investigator Eric J. Dippel, MD, of Genesis Heart Institute in Davenport, Iowa, at the annual New Cardiovascular Horizons conference in New Orleans last week demonstrated significant procedural advantage of laser atherectomy in the largest randomized trial of atherectomy ever conducted.
Percutaneous coronary intervention without surgical backup did not increase the risk of inhospital mortality or need for emergency bypass surgery, according to a systematic review of published literat
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).. Learn more at ClinicalTrials.gov NCT03108456. ...
In this work, the stents-induced mechanical responses of a patient-specific common carotid artery (CCA) were evaluated through computational simulation. The realistic 3D geometry of the artery was constructed from the MRI data. Two types of self-expanding stent design (open-cell and closed-cell) were used to restore the blood flow inside the 60% stenosed artery. The resulting lumen gain, dog-boning effect and arterial stress were estimated. Results suggested that the artery was straightened after stent implantation, and the open-cell design led to bigger lumen gain, better conformability, and less dog-boning effect. This work may facilitate the development of new stent designs.. Copyright © 2011 by ASME ...
The Companys primary, non-AGGRASTAT research and development activity is TARDOXAL(TM) for the treatment of Tardive Dyskinesia (TD). The Company is currently awaiting interim results from the Phase II clinical study of TARDOXAL, entitled Tardoxal for the Treatment of Tardive Dyskinesia (TEND-TD). The Companys ability to continue in operation for the foreseeable future remains dependent upon the effective execution of its business development and strategic plans. All amounts referenced herein are in Canadian dollars unless otherwise noted. About AGGRASTAT AGGRASTAT (tirofiban HCl), in combination with heparin, is indicated for the treatment of acute coronary syndrome, including patients who are to be managed medically and those undergoing PTCA or atherectomy. In this setting, AGGRASTAT has been shown to decrease the rate of a combined endpoint of death, new myocardial infarction or refractory ischemia/repeat cardiac procedure. AGGRASTAT has been studied in a setting that included aspirin and ...
An improved expandable removal element (16) for an atherectomy device wherein the expandable removal element (16) is movable between an expanded position and a contracted position. In one embodiment o
The present invention provides an atherectomy catheter which has a cutting element that is able to cut both soft tissue and hard tissue, and methods of cutting material from a blood vessel lumen using a rotating cutting element. The cutting element has a sharp cutting edge that surrounds a cup-shaped surface and at least one surface of abrasive material. The cup-shaped surface directs the cut material into a tissue chamber. The cutting edge and the cup-shaped surface together are well suited to cut and remove relatively soft tissue from the blood vessel. The abrasive material surface in combination with the cutting element is well suited to abrade and remove hard material from the blood vessel.
To the best of our knowledge, this is the first report of OCT evaluation of SFA atherectomy in a patient from the Asia-Pacific region. We demonstrate the feasibility of this technique in Chinese populations ...
I will have to caveat though and stress that it is a delicate paper by nature, so when heavier things are used on it like my collage bits, the seam of that particular page does become a little weak and may sort of shear off a bit if you handle the page too much. This also may because originally it was made to be able to tear off since its original intention was to be used as a calendar. Not quite sure, but that is my assumption ...
I will have to caveat though and stress that it is a delicate paper by nature, so when heavier things are used on it like my collage bits, the seam of that particular page does become a little weak and may sort of shear off a bit if you handle the page too much. This also may because originally it was made to be able to tear off since its original intention was to be used as a calendar. Not quite sure, but that is my assumption ...
Harbin Clinic is Georgias largest physician-owned, multi-specialty clinic with more than 220 providers across more than 30 specialties in 20 locations throughout Northwest Georgia. Since 1870 the Harbin family has practiced medicine in the region, founding the Harbin Hospital in 1908 in Rome, Georgia. That hospital grew into the present Harbin Clinic which cares for thousands of patients each day. Harbin Clinic Cares Completely.. Read more posts by Harbin Clinic. ...
Evidence-based recommendations on percutaneous laser atherectomy with balloon angioplasty (with or without stenting) for peripheral arterial disease (PAD)
Evidence-based recommendations on percutaneous laser atherectomy with balloon angioplasty (with or without stenting) for peripheral arterial disease (PAD)
Hello and welcome to the December issue of Vascular Disease Management. I have chosen to comment on Deepika Kalisetta and colleagues case report on Balloon Assisted Dislodgement of a Trapped Directional Atherectomy Catheter (the Ocelot device) During Treatment of In-Stent Restenosis (ISR).. Stenting of femoropopliteal arterial obstructive lesions has been demonstrated to result in higher primary patency than standard balloon angioplasty. Stenting is also routinely utilized to treat flow-limiting dissections following PTA and atherectomy. Therefore, stenting is commonly utilized in treating symptomatic femoral and popliteal arterial obstructions. Unfortunately, restenosis and reocclusion are common following stenting. Whereas stent grafts tend to develop recurrent stenosis only at the edge of the stents, standard nitinol self-expanding stents often develop diffuse in-stent restenosis secondary to neointimal hyperplasia and reocclusion when there is superimposed thrombus. Stent restenosis can ...
From February to August 1997, 64 patients were enrolled in a study of intracoronary gamma radiation for in-stent restenosis. In the present study, we analyzed 37 lesions (31 native coronary and 6 vein graft) in 36 patients (age, 62±10 years; 24 men) previously treated with Palmaz-Schatz stents (Cordis). Reasons for exclusion were restenting of the lesions (n=13), no delayed (n=6) or inadequate IVUS (n=1), in-stent tissue ,75% of stent cross-sectional area (CSA; n=2), restenosis localized to stent margin(s) (n=1), or presence of non-Palmaz-Schatz stents (n=5). (One patient had 2 lesions; per protocol, only 1 was enrolled in the radiation trial.) There were 65 stents (1.8 per lesion), implanted 9.6±8.3 months previously. Fifteen patients (40%) had prior in-stent restenosis; the last episode was 5.5±3.3 months previously.. Primary treatment strategy was determined by the operator: PTCA (n=8), excimer laser coronary angioplasty (ELCA; Spectranetics; n=12) + adjunct PTCA, or rotational atherectomy ...
SYSTEM AND METHOD OF USE FOR AGENT DELIVERY AND REVASCULARIZING OF GRAFTS AND VESSELS - A system and method for opening a lumen in an occluded blood vessel, e.g., a coronary bypass graft, of a living being. The system comprises an atherectomy catheter having a working head, e.g., a rotary impacting impeller, and a debris extraction sub-system. The atherectomy catheter is located within a guide catheter. The working head is arranged to operate on, e.g., impact, the occlusive material in the occluded vessel to open a lumen therein, whereupon some debris may be produced. The debris extraction sub-system introduces an infusate liquid at a first flow rate adjacent the working head and withdraws that liquid and some blood at a second and higher flow rate, through the guide catheter to create a differential flow adjacent the working head, whereupon the debris is withdrawn in the infusate liquid and blood for collection outside the beings body. The introduction of the infusate liquid may also be used ...
As Dr. Robert Harrington, Chief of Medicine at Stanford University, describes:. "Every patient case became a rather detailed discussion around what was best. And remember the days of cath conferences where there would be much discussion and even heated debate amongst interventional cardiologists, non-invasive cardiologists and our surgical colleagues about what might be the appropriate approach for that particular patient.". Then came stents: metal scaffolds that had the ability to hold the artery open after the balloon inflation. Soon the complications of angioplasty that resulted in emergency bypass surgery became one in a thousand or less. The procedure became much safer. So much so that it became feasible, even desirable, to add another 30 minutes or so onto the diagnostic procedure and open up the blockage. One stop shopping…or stenting: ad hoc angioplasty!. What was gained was efficiency, less patient discomfort, lower costs…what was lost was that period of decision-making, of debate ...
Paclitaxel: Paclitaxel in addition to angioplasty, stenting or atherectomy Dosing will be based on the lesion surface area, and will be calculated using the following formula: dose= 22/7 X diameter (mm) X length (mm) X 3 micrograms/mm^3. Paclitaxel Dosage:. Superficial Femoral/Common Femoral: 2.4 mg/inflation of balloon* Popliteal: 1.8 mg/inflation of balloon* Tibial: 1.4 mg/inflation of balloon*. ...
by Caldwell B. Esselstyn, Jr., MD. THE AMERICAN JOURNAL OF CARDIOLOGY VOL. 84 , August 1, 1999. "Modern cardiology has given up on curing heart disease. Its aggressive interventions- coronary artery bypass graft, atherectomy, angioplasty, and stenting-do not reduce the frequency of new heart attacks or prolong survival except in small subsets of patients.1 For most patients these procedures do not treat life-threatening plaques.1,2 Thus, it is clear that the goal of cardiology has become the relief of pain and unpleasant symptoms in the face of progressive disability and often death from disease. It is time to call this approach by its true name: palliative cardiology. It is also time to acknowledge that this approach is not the only alternative for our patients.". ...
Atherectomy is a minimally invasive treatment used to remove plaque buildup inside of large blood vessels. Typically, the vascular surgeon will access the patients blood vessel via a small incision in the groin. A catheter is then advanced to the part of the vessel that has too much plaque buildup. Techniques used to remove the plaque include spinning the catheter in a circular motion, back and forth motion of the catheter, orbital devices advanced inside of the catheter, More >> ...
CLINICAL CLASSIFICATIONS FOR ICD-9-CM PROCEDURES BY THE HEALTHCARE COST AND UTILIZATION PROJECT (HCUP) PATIENTS WITH CANCER (MALIGNAT NEOPLASMS) ICD-9-CM: 140-209 __________________________________________________________________________________ Automatic Impliantable Cardioverter/Defibrillator (AICD) Check 89.49 Abdominal Paracentesis 54.91 Alcohol and Drug Rehabilitation/Detoxification 94.61-94.69 Amnioinfusion 75.37 Amputation of Lower Extremity 84.10-84.19 Anatomic and Physiologic Measurements and Manual Examinations, Except EEG and Nonoperative Urinary System Measurements 89.10-89.13,89.15-89.19 89.20-89.28 89.30-89.39 Angloplasty or Atherectomy of Other Non-Coronary Vessels 39.50 Aortic Resection; Replacement or Anastomosis 38.34 38.44 38.64 38.71 38.73 Appendectomy 47.01 47.09 47.11 47.19 Arterio- or Venogram (not Heart & Head) 88.40 88.43-88.47 88.49-88.51 88.58 88.60-88.68 Arthrocentesis 89.91 Arthroplasty Knee 00.80-00.84 81.41-81.44 81.46-81.47 81.54-81.55 Arthroplasty Other Than Hip ...
Cardiovascular Systems, Inc. (CSI) is a medical device company. The company develops and commercializes solutions for treating peripheral and coronary vascular disease. Its products include orbital atherectomy system, accessories, crowns, and asahi-intecc guide wires.
On sheet 1 I have a staff rota that has about 50 names listed in column A and dates across row 1. (50*365 cells) on sheet 2 The dates will be across the top as per sheet one I would like to input a name in cell A3 and that persons rota for the year appears in row 3. and so on for each ...
We provide a state-of-the-art intracoronary imaging system that helps you optimize the treatment of patients and master complex lesions. Our optics-based imagin
Major clinical events during six months follow up were death, emergency bypass surgery, stent thrombosis related myocardial infarction (Q wave or non-Q wave), out-of-hospital stent thrombosis, and vascular complications. Stent thrombosis related Q wave myocardial infarction was defined as documentation of new pathological Q waves (more than 0.04 seconds) in conjunction with increased activity of creatine kinase (CK) to more than twice the upper limit of normal. Stent thrombosis related non-Q wave myocardial infarction was defined as increased activities of cardiac enzymes to more than twice the upper limit of normal without new pathological Q waves. Out-of-hospital stent thrombosis was defined as any unexplained sudden death or myocardial infarction in the stented vessel. Vascular complications were defined as bleeding or haematoma at the access site requiring transfusion, vascular repair, or external compression.. Electrocardiograms were recorded immediately after implantation, then daily for ...
The Highlights of my practice are: Laparascopic, Single incision and Scarless approaches to many surgical problems. I Perform wide range of surgical services at my facility ( Minimal Invasive Surgery Center ), also at Jupiter Medical Center and Palm Beach Gardens Hospital so I can meet the specific needs of all my patients.
For coronary artery disease treatments such as coronary angioplasty, balloon angioplasty and atherectomy, seek care world class care at BWH.
The study by den Heijer and colleagues is of interest to both interventional cardiologists and internists. The availability of low-profile, flexible, and steerable angioscopic systems has allowed the routine percutaneous application of this technology. Interpretable images can now be obtained in most patients having interventional procedures, although the technique still has important limitations. Problems remain with aiming the angioscope, and a clear imaging field cannot always be obtained. The widespread availability of second-generation interventional technologies, including stents, atherectomy catheters, and local drug delivery systems, give the interventionist a choice of therapies. Precise knowledge of coronary morphology may have an important effect on the decision of which technique to use to treat a given lesion. The study by den Heijer and colleagues suggests that, in a few patients, the angioscopic information was useful to the clinician. These results, however, cannot be ...
[173 Pages Report] Interventional Cardiology Devices Market categories the Global market by type (Angioplasty, Catheters, Plaque Modification (Atherectomy, Thrombectomy), Hemodynamic Flow Alteration (Embolic Protection, Total Occlusion), Guidewire, Introducer Sheath)) & Geography
This is a call for feedback for individuals and groups, both academic and industrial, who have used or are using the molecular design program CAVEAT. We in the Bartlett group at UC Berkeley (the birthplace of said program) are contemplating the formation of some form of electronic forum for users of CAVEAT, and would appreciate hearing comments and critiques based on your experiences. Please direct all correspondence to mark at gall.cchem.berkeley.edu For the uninitiated, CAVEAT is a database searching program which facilitates the design of new molecular structures--most commonly biologically active ligands such as enzyme inhibitors--and is conceptually quite different from most other such programs. For further information, access the Bartlett group www home page at: http://www.cchem.berkeley.edu/~pabgrp Mark ...
Get this from a library! A defence of the Reply to the Caveat, &c. : in Answer to Mr. Stogdon: wherein, His own and his Tutor Witherss Cavils are Exposd ; Their false Reasonings and wicked Suggestions are laid Open ; And their Designs in publishing that Caveat, and the Defence of it, are shewn to be nothing else but Scandal and Defamation. In the way of letter to a Friend. By Benjamin Reed.. [Benjamin Reed]
Greg Robertson, MD, is the chief of the Emory Heart and Vascular Clinic at Johns Creek. At the Emory Johns Creek Hospital he is chief of cardiology and the medical director of the Cardiac Catheterization laboratory and interventional program. He is board certified in Vascular Medicine, Endovascular Medicine, Interventional Cardiology and Cardiovascular Medicine.. Dr. Robertsons research has had a focus on the development of new technologies and techniques to treat blocked leg arteries in patients with peripheral arterial disease, helping patients walk farther and prevent limb amputation in diabetic patients. While in the San Francisco Bay Area for 16 years before moving to Atlanta, he practiced with the well-known medical device inventor Dr. John Simpson, whose development teams invented the atherectomy procedure and the first percutaneous arterial closure device. Atherectomy is a procedure which allows the physician to remove plaque in blocked arteries without major surgery. His newest project ...
To help elucidate the mechanism of excimer laser coronary angioplasty (ELCA), intravascular ultrasound (IVUS) imaging was performed in 19 of 29 patients who were treated with ELCA. The results were compared with a non-randomized control group of 18 p
The Willis-Knighton Heart & Vascular Institute provides the following Peripheral Vascular Disease Treatments Carotid Stents, Abdominal Aortic Aneurysm Stent Grafts, Renal Angioplasty & Stents, Peripheral Laser Atherectomy and Cryo-Balloon Angioplasty.
Expertise, Disease and Conditions: Acute Myocardial Infarction (AMI), Adult Congenital Heart Disease, Angina, Angioplasty, Aortic Coarctation, Arrhythmia, Atrial Septal Defects (ASD), Balloon Valvuloplasty, Cardiac Catheterization, Cardiomyopathy, Cardiovascular Disease, Cardiovascular Diseases, Cardiovascular Interventions, Cardiovascular Medicine, Coronary Angiography, Coronary Artery Disease, Coronary Artery Stenting, Drug Eluting Stents, Extractional Atherectomy, Heart Attack, Heart Disease, Heart Failure, Interventional Cardiology, Interventional Radiology, Invasive Cardiology, Irregular Heartbeat, Ischemic Heart Disease, Laser Ablation, Mitral Stenosis, Myocardial Infarction, New Imaging Modalities, Patent Ductus Arteriosus (PDA), Patent Foramen Ovale, Percutaneous Coronary Intervention (PCI), Percutaneous Treatment of Valvular Stenosis, Pulmonary Stenosis, Rotational Atherectomy, Stenting, Treatment of Bypass Graft Disease with Distal Protection Devices, Valvular Heart Disease, ...
The use of IVUS has also led to important advances in the understanding of the natural history, distribution, and morphology of CAV (16,17,20-22,72,73). Serial IVUS imaging has shown that the dynamic process of coronary artery remodeling begins within the first year after transplantation (74). Initially, there is thickening of the coronary intima, which occurs in more than 80% of patients within 1 year after transplantation (16,17,63). In addition, affected arteries develop an early expansion of the external elastic membrane with preservation of luminal area (75-77). Changes in the external elastic membrane tend to occur in a biphasic pattern, with early expansion followed by late, concentric remodeling and reductions in luminal area (77).. Radiofrequency IVUS has been investigated in traditional atherosclerotic CAD to delineate the components of coronary lesions and classify plaque based on its composition (78-80). In transplant recipients, it has demonstrated that lesions in the early ...
BACKGROUND: This study is the third in a series of investigations on the requisite length of time that patients should be restricted to bed after coronary arteriography or percutaneous transluminal coronary angioplasty using a femoral artery approach. METHODS: A prospective, experimental-control group design with randomization was used initially to compare the incidence of bleeding between patients who remained in bed for 4 hours and patients who remained in bed for 6 hours after sheath removal following percutaneous transluminal coronary angioplasty. RESULTS: Rapid changes in the healthcare environment led to nurses collecting complete data sets for the experimental group only. The experimental group (n = 51) was 73% male and 27% female; mean age was 57 years (SD = 11.4 years). Mean time in bed was 4.1 hours (SD = 0.27 hours). Most patients (98%) did not bleed from the femoral artery access site after remaining in bed for 4 hours following sheath removal. Ninety-two percent of patients required ...

Top Coronary Atherectomy Hospitals in Chennai  | CredihealthTop Coronary Atherectomy Hospitals in Chennai | Credihealth

Get guidance from medical experts to select best coronary atherectomy hospital in Chennai ... View details of top coronary atherectomy hospitals in Chennai. ... Best hospitals for coronary-atherectomy in Chennai List of best ... Need help in choosing the right coronary atherectomy hospital? The medical expert will guide you for all hospital needs ... Need help in choosing the right coronary atherectomy hospital? The medical expert will guide you for all hospital needs ...
more infohttps://www.credihealth.com/hospitals/chennai/coronary-atherectomy

Coronary Angioplasty Versus Excisional Atherectomy Trial I - American College of CardiologyCoronary Angioplasty Versus Excisional Atherectomy Trial I - American College of Cardiology

Keywords: Myocardial Infarction, Coronary Angiography, Atherectomy, Constriction, Pathologic, Angioplasty, Balloon, Coronary , ... Coronary Angioplasty Versus Excisional Atherectomy Trial I - CAVEAT I. Feb 04, 2002 Share via: ... Directional atherectomy was associated with a trend toward lower rates of restenosis at 6 months, and increased mortality and ... Directional atherectomy (DCA), balloon angioplasty (PTCA). Concomitant Medications: Aspirin, calcium channel blockade, heparin ...
more infohttp://www.acc.org/latest-in-cardiology/clinical-trials/2010/02/23/18/58/caveat-i

1993 - Atherectomy led to a greater gain in lumen size than did balloon angioplasty
         but restenosis rates and clinical...1993 - Atherectomy led to a greater gain in lumen size than did balloon angioplasty but restenosis rates and clinical...

The Coronary Angioplasty versus Excisional Atherectomy Trial (CAVEAT) by Topol and colleagues and the Canadian Coronary ... A comparison of directional atherectomy with coronary angioplasty in patients with coronary artery disease. N Engl J Med. 1993 ... The coronary atherectomy catheter (Simpson Coronary Atherocath) has subsequently been modified, guiding catheter technology has ... coronary atherectomy (DCA) is superior to PTCA in reducing restenosis. Despite initial claims by atherectomy enthusiasts and ...
more infohttp://www.acpjc.org/Content/120/1/issue/ACPJC-1994-120-1-004.htm

Most recent papers with the keyword Excimer laser coronary angioplasty | Read by QxMDMost recent papers with the keyword Excimer laser coronary angioplasty | Read by QxMD

Excimer coronary laser atherectomy (ECLA) has been shown to be both well tolerated and effective for plaque modification. Its ... OBJECTIVES: This study aims to determine how excimer laser coronary atherectomy (ELCA) performs in the drug-eluting stent (DES ... Laser atherectomy might decrease procedural complications during percutaneous coronary intervention (PCI) of degenerated ... DIAGNOSES: Coronary angiography revealed a tight stenosis at the right coronary artery which resulted in treatment by PCI... ...
more infohttps://www.readbyqxmd.com/keyword/9843

Saphenous Vein Bypass Graft Disease Hardcover Books - Buy Saphenous Vein Bypass Graft Disease Online at Lowest Price - Infibeam...Saphenous Vein Bypass Graft Disease Hardcover Books - Buy Saphenous Vein Bypass Graft Disease Online at Lowest Price - Infibeam...

... outlines directional coronary atherectomy and transluminal extraction atherectomy -focuses on the pathologic changes resulting ... Pooling the experience of over 25 coronary specialists, Saphenous Vein Bypass Graft Disease -describes early and late ...
more infohttps://assets.infibeam.com/Books/info/Eric-R-Bates/Saphenous-Vein-Bypass-Graft-Disease/082479902X.html

Enhanced External Counterpulsation - procedure, test, blood, pain, time, graft, medication, heartEnhanced External Counterpulsation - procedure, test, blood, pain, time, graft, medication, heart

... atherectomy, or brachytherapy. It may also be used for patients who do not qualify for such surgical treatment as coronary ... Coronary artery bypass graft surgery is a surgical procedure in which one or more blocked coronary arteries are bypassed by a ... All patients with coronary artery disease can help improve their condition by making such lifestyle changes as quitting smoking ... All patients with coronary artery disease should be prescribed medications to treat their condition. Such Antiplatelet ...
more infohttps://www.surgeryencyclopedia.com/Ce-Fi/Enhanced-External-Counterpulsation.html

Directional coronary atherectomy (DCA) - Health Video: MedlinePlus Medical EncyclopediaDirectional coronary atherectomy (DCA) - Health Video: MedlinePlus Medical Encyclopedia

... is a minimally invasive procedure to remove the blockage from the coronary arteries and allow more blood to flow to the heart ... Directional Coronary Atherectomy (DCA) is a minimally invasive procedure to remove the blockage from the coronary arteries and ... Once the catheter is placed in the opening or ostium of one of the coronary arteries, the doctor injects dye and takes an x-ray ... A device called a stent may be placed within the coronary artery to keep the vessel open. After the intervention is completed ...
more infohttp://medlineplus.gov/ency/anatomyvideos/000042.htm

Canadian Coronary Atherectomy Trial - American College of CardiologyCanadian Coronary Atherectomy Trial - American College of Cardiology

Coronary, Death, Sudden, Coronary Disease, Constriction, Pathologic, Coronary Vessels, Angioplasty, Balloon, Coronary ... Stenosis of ≥ 60% in the proximal third of the left anterior descending coronary artery Lesion suitable for either atherectomy ... Left main coronary stenosis exceeding 25 percent. Acute myocardial infarction within 1 week. Severe left ventricular ... Fifty-eight percent of all atherectomy procedures performed at the study centers were included in the trial.. Angiographic ...
more infohttp://www.acc.org/latest-in-cardiology/clinical-trials/2010/02/23/18/58/ccat

Coronary atherectomy | definition of coronary atherectomy by Medical dictionaryCoronary atherectomy | definition of coronary atherectomy by Medical dictionary

What is coronary atherectomy? Meaning of coronary atherectomy medical term. What does coronary atherectomy mean? ... Looking for online definition of coronary atherectomy in the Medical Dictionary? coronary atherectomy explanation free. ... 55, transluminal coronary atherectomy, directional atherectomy, excimer laser atherectomy, rotational atherectomy, that by ... coronary atherectomy. A technique of removing obstructions from the coronary artery with a cutting instrument inserted through ...
more infohttp://medical-dictionary.thefreedictionary.com/coronary+atherectomy

Preliminary experience at a Canadian centre with directional coronary atherectomy for complex lesions.Preliminary experience at a Canadian centre with directional coronary atherectomy for complex lesions.

DESIGN: Nonrandomized, sequential patients with coronary arterial lesions that were ostial, eccentric, bulky, recurrent or ... To evaluate preliminary experience of directional coronary atherectomy for complex coronary artery lesions. ... OBJECTIVE: To evaluate preliminary experience of directional coronary atherectomy for complex coronary artery lesions. DESIGN: ... Angioplasty, Transluminal, Percutaneous Coronary. Coronary Angiography. Coronary Artery Disease / radiography, surgery*, ...
more infohttp://www.biomedsearch.com/nih/Preliminary-experience-at-Canadian-centre/1756419.html

Directional coronary atherectomy (DCA) | Multimedia Encyclopedia | Health Information | St. Lukes HospitalDirectional coronary atherectomy (DCA) | Multimedia Encyclopedia | Health Information | St. Luke's Hospital

Directional Coronary Atherectomy (DCA) is a minimally invasive procedure to remove the blockage from the coronary arteries and ... Once the catheter is placed in the opening or ostium of one of the coronary arteries, the doctor injects dye and takes an x-ray ... A device called a stent may be placed within the coronary artery to keep the vessel open. After the intervention is completed ...
more infohttps://www.stlukes-stl.com/health-content/health-ency-multimedia/17/000042.htm

Philips - ELCA coronary laser atherectomy catheterPhilips - ELCA coronary laser atherectomy catheter

... prepare and treat the most complex coronary lesions. ... ELCA coronary laser atherectomy catheters are designed to cross ... coronary spasm, coronary embolism, coronary perforation, laser/stent damage, balloon/stent damage, and other serious. ... Coronary laser atherectomy catheter IGTDELCALASR Bekijk soortgelijke producten ... prepare and treat the most complex coronary lesions. This non-mechanical atherectomy catheter can be delivered over any .014" ...
more infohttps://www.philips.nl/healthcare/product/HCIGTDELCALASR/elca-coronary-laser-atherectomy-catheter/overzicht

Benodigdheden | ELCA Coronary laser atherectomy catheter | PhilipsBenodigdheden | ELCA Coronary laser atherectomy catheter | Philips

Meer informatie over ELCA Coronary laser atherectomy catheter. Bekijk specificaties, download ondersteuningsdocumenten en ... Coronary laser atherectomy catheter Bekijk soortgelijke producten ELCA coronary laser atherectomy catheters are designed to ... coronary spasm, coronary embolism, coronary perforation, laser/stent damage, balloon/stent damage, and other serious. ... This non-mechanical atherectomy catheter can be delivered over any .014" wire and can de-bulk and modify plaque of multiple ...
more infohttps://www.philips.nl/healthcare/product/HCIGTDELCALASR/elca-coronary-laser-atherectomy-catheter/accessoires

Vlastnosti | ELCA Coronary laser atherectomy catheter | PhilipsVlastnosti | ELCA Coronary laser atherectomy catheter | Philips

Learn more about ELCA Coronary laser atherectomy catheter. View specifications, download support documents and discover related ... Coronary laser atherectomy catheter Najít podobné výrobky ELCA coronary laser atherectomy catheters are designed to cross, ... coronary spasm, coronary embolism, coronary perforation, laser/stent damage, balloon/stent damage, and other serious. ... prepare and treat the most complex coronary lesions. This non-mechanical atherectomy catheter can be delivered over any .014" ...
more infohttps://www.philips.cz/healthcare/product/HCIGTDELCALASR/elca-coronary-laser-atherectomy-catheter/vlastnosti

Related products | ELCA Coronary laser atherectomy catheter | PhilipsRelated products | ELCA Coronary laser atherectomy catheter | Philips

Learn more about ELCA Coronary laser atherectomy catheter. View specifications, download support documents and discover related ... Coronary laser atherectomy catheter Find similar products ELCA coronary laser atherectomy catheters are designed to cross, ... coronary spasm, coronary embolism, coronary perforation, laser/stent damage, balloon/stent damage, and other serious. ... prepare and treat the most complex coronary lesions. This non-mechanical atherectomy catheter can be delivered over any .014" ...
more infohttps://www.philips.ca/healthcare/product/HCIGTDELCALASR/elca-coronary-laser-atherectomy-catheter/relatedproducts

Atherectomy, coronary synonyms, Atherectomy, coronary antonyms - FreeThesaurus.comAtherectomy, coronary synonyms, Atherectomy, coronary antonyms - FreeThesaurus.com

... coronary in Free Thesaurus. Antonyms for Atherectomy, coronary. 4 words related to endarterectomy: ablation, cutting out, ... Atherectomy, coronary synonyms, Atherectomy, coronary antonyms - FreeThesaurus.com https://www.freethesaurus.com/Atherectomy%2c ... Atherectomy, coronary provided by ,a style=color:#000 href=https://www.freethesaurus.com/Atherectomy%2c+coronary, ... redirected from Atherectomy, coronary). Also found in: Dictionary, Medical. #vtZoom,.vt-link{cursor:pointer} .vt-container{ ...
more infohttps://www.freethesaurus.com/Atherectomy%2C+coronary

Evaluation of the Diamondback 360 Coronary Orbital Atherectomy System for treating de novo, severely calcified lesions.Evaluation of the Diamondback 360 Coronary Orbital Atherectomy System for treating de novo, severely calcified lesions.

Coronary lesions with severe (or heavy) calcification are classified as complex lesions and are known to carry lower success ... rates and higher complication rates following percutaneous coronary intervention. The Diamondback 360(®) Coronary Orbital At ... The Diamondback 360(®) Coronary Orbital Atherectomy System is the first and only device approved for use in the USA as a ... Coronary lesions with severe (or heavy) calcification are classified as complex lesions and are known to carry lower success ...
more infohttp://www.biomedsearch.com/nih/Evaluation-Diamondback-360-Coronary-Orbital/24961517.html

Diamondback 360® Coronary Orbital Atherectomy System | CSI360Diamondback 360® Coronary Orbital Atherectomy System | CSI360

Coronary Orbital Atherectomy System (OAS). Coronary Orbital Atherectomy System (OAS). The only atherectomy device indicated to ... Coronary Orbital Atherectomy System. INDICATION & IMPORTANT SAFETY INFORMATION. Indication: The DIAMONDBACK 360® Coronary ... Home » Coronary » Diamondback 360® Coronary Orbital Atherectomy System. Diamondback 360® ... Coronary Artery Disease (CAD). Coronary Artery Disease (CAD). Often referred to as blocked arteries, CAD is the most common ...
more infohttps://csi360.com/products/diamondback-360-coronary-orbital-atherectomy-system/

CRT-200.21 Transvenous Pacemaker Placement Incidence With Coronary Orbital Atherectomy Compared to Rotational Atherectomy |...CRT-200.21 Transvenous Pacemaker Placement Incidence With Coronary Orbital Atherectomy Compared to Rotational Atherectomy |...

Diamondback 360® Coronary Orbital Atherectomy System (OAS) is a device which can treat calcific coronary artery disease (CAD) ... Coronary. CRT-200.21 Transvenous Pacemaker Placement Incidence With Coronary Orbital Atherectomy Compared to Rotational ... CRT-200.21 Transvenous Pacemaker Placement Incidence With Coronary Orbital Atherectomy Compared to Rotational Atherectomy ... CRT-200.21 Transvenous Pacemaker Placement Incidence With Coronary Orbital Atherectomy Compared to Rotational Atherectomy ...
more infohttp://interventions.onlinejacc.org/content/9/4_Supplement/S8.3

c9602 HCPCS Code | Percutaneous transluminal coronary atherectomy, with drug eluting intracoronary stent, with coronary...c9602 HCPCS Code | Percutaneous transluminal coronary atherectomy, with drug eluting intracoronary stent, with coronary...

... with coronary angioplasty when performed; single major coronary artery or branch ... HCPCS Code Description: Percutaneous transluminal coronary atherectomy, with drug eluting intracoronary stent, ... Percutaneous transluminal coronary atherectomy, with drug eluting intracoronary stent, with coronary angioplasty when performed ... Percutaneous transluminal coronary atherectomy, with drug eluting intracoronary stent, with coronary angioplasty when performed ...
more infohttps://www.hipaaspace.com/medical_billing/coding/healthcare.common.procedure.coding.system/c9602

Safety and Efficacy of Rotational Atherectomy (RA) in Coronary Dissection - Full Text View - ClinicalTrials.govSafety and Efficacy of Rotational Atherectomy (RA) in Coronary Dissection - Full Text View - ClinicalTrials.gov

Coronary Artery Disease Procedure: Immediate rotational atherectomy (RA) Procedure: Delayed rotational atherectomy (RA) Phase 1 ... Coronary artery dissection is a contraindication for the use of rotational atherectomy, since rotational atherectomy may ... Safety and Efficacy of Rotational Atherectomy (RA) in Coronary Dissection. The safety and scientific validity of this study is ... Immediate rotational atherectomy (RA) in the treatment with nondilatable calcified lesion complicated by coronary dissection ...
more infohttps://clinicaltrials.gov/ct2/show/NCT01701596

Best Coronary Atherectomy Specialist in Chennai - Book Appointment Online at Top Hospitals | CredihealthBest Coronary Atherectomy Specialist in Chennai - Book Appointment Online at Top Hospitals | Credihealth

... feedback and reviews of top coronary atherectomy specialists near you. Get upto 25% discount on OPD fees of coronary ... Get help from medical experts to select the right coronary atherectomy doctor from top hospitals in Chennai. View profile, fees ... Best doctors for coronary-atherectomy in Chennai List of best Coronary Atherectomy Doctors from trusted hospitals in Chennai. ... List of best Coronary Atherectomy Doctors from trusted hospitals in Chennai. Get detailed info on educational qualification, ...
more infohttps://www.credihealth.com/doctors/chennai/coronary-atherectomy

CRT-100.02 Treatment of Severely Calcified Coronary Lesions With the Coronary Orbital Atherectomy System Micro Crown: Early...CRT-100.02 Treatment of Severely Calcified Coronary Lesions With the Coronary Orbital Atherectomy System Micro Crown: Early...

CRT-100.02 Treatment of Severely Calcified Coronary Lesions With the Coronary Orbital Atherectomy System Micro Crown: Early ... CRT-100.02 Treatment of Severely Calcified Coronary Lesions With the Coronary Orbital Atherectomy System Micro Crown: Early ... CRT-100.02 Treatment of Severely Calcified Coronary Lesions With the Coronary Orbital Atherectomy System Micro Crown: Early ... The Diamondback 360 Coronary Orbital Atherectomy System (OAS) Classic Crown was the first device approved by the Food and Drug ...
more infohttp://interventions.onlinejacc.org/content/9/4_Supplement/S1.3

Coronary angioplasty and Rotablator atherectomy trial (CARAT): immediate and late results of a prospective multicenter...Coronary angioplasty and Rotablator atherectomy trial (CARAT): immediate and late results of a prospective multicenter...

Mechanical rotational atherectomy with the Rotablator is widely used for percutaneous coronary revascularization, but the ideal ... Coronary angioplasty and Rotablator atherectomy trial (CARAT): immediate and late results of a prospective multicenter ... 12.7%, P , 0.05) immediately after atherectomy. This study suggests that a routine lesion modification strategy employing small ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/11387607

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty...Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty...

Coronary heart disease , Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. ... Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty ... This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of ...
more infohttps://www.centerwatch.com/clinical-trials/listings/116075/coronary-artery-disease-evaluation-treatment-strategies-severe/?geo_lat=42.4377&geo_lng=-82.9289&radius=10
  • Optimal Spaced Excimer Laser Coronary Catheters Performance Analysis, Journal of Clinical Laser Medicine and Surgery, Vol 19, Issue 1, 9-14. (philips.nl)
  • METHODS: We retrospectively analyzed the medical records of all patients with severe AS who underwent OA-facilitated percutaneous coronary intervention (PCI) at our center between September 1, 2015 and November 1, 2018. (umassmed.edu)
  • Completing ORBIT II enrollment is a significant milestone in our efforts to secure a coronary indication to treat arterial calcium-a vastly underestimated problem in medicine today," said David L. Martin, CSI president and chief executive officer. (medlatest.com)
  • Two patients' coronary atheromas were positive, both by a singlestep 16S rRNA-based PCR and by an omp1 -based nested PCR. (oup.com)
  • Of three patients with evidence of C. pneumoniae in coronary atheromas, two had an antibody titer of 1:32 and the third had no specific antibodies detectable. (oup.com)
  • Results of this study demonstrate a low prevalence of C. pneumoniae DNA in coronary atheromas. (oup.com)
  • This study has several potential limitations: (1) Our study groups were small, due to very limited number of patients underwent coronary atherectomy in our centre at the time interval (July 2002-September 2004) of the study. (thefreedictionary.com)
  • Atherectomy is a minimally invasive endovascular surgery technique for removing atherosclerosis from blood vessels within the body. (wikipedia.org)
  • Our CVX-300(R) excimer laser is the only system approved by the FDA for multiple cardiovascular procedures, including coronary atherectomy , the treatment of in-stent restenosis prior to radiation therapy, and the removal of problematic pacemaker and defibrillator leads. (thefreedictionary.com)