Percutaneous transluminal procedure for removing atheromatous plaque from the coronary arteries. Both directional (for removing focal atheromas) and rotational (for removing concentric atheromatous plaque) atherectomy devices have been used.
Endovascular procedure in which atheromatous plaque is excised by a cutting or rotating catheter. It differs from balloon and laser angioplasty procedures which enlarge vessels by dilation but frequently do not remove much plaque. If the plaque is removed by surgical excision under general anesthesia rather than by an endovascular procedure through a catheter, it is called ENDARTERECTOMY.
The veins and arteries of the HEART.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
The circulation of blood through the CORONARY VESSELS of the HEART.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Narrowing or constriction of a coronary artery.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
A technique utilizing a laser coupled to a catheter which is used in the dilatation of occluded blood vessels. This includes laser thermal angioplasty where the laser energy heats up a metal tip, and direct laser angioplasty where the laser energy directly ablates the occlusion. One form of the latter approach uses an EXCIMER LASER which creates microscopically precise cuts without thermal injury. When laser angioplasty is performed in combination with balloon angioplasty it is called laser-assisted balloon angioplasty (ANGIOPLASTY, BALLOON, LASER-ASSISTED).
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
The return of a sign, symptom, or disease after a remission.
Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
Spasm of the large- or medium-sized coronary arteries.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
Pathologic deposition of calcium salts in tissues.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Elements of limited time intervals, contributing to particular results or situations.
The condition of an anatomical structure's being constricted beyond normal dimensions.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
The degree to which BLOOD VESSELS are not blocked or obstructed.
The main artery of the thigh, a continuation of the external iliac artery.
Motion pictures of the passage of contrast medium through blood vessels.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Obstruction of flow in biological or prosthetic vascular grafts.
The hospital unit in which patients with acute cardiac disorders receive intensive care.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
A condition that is caused by recurring atheroembolism in the lower extremities. It is characterized by cyanotic discoloration of the toes, usually the first, fourth, and fifth toes. Discoloration may extend to the lateral aspect of the foot. Despite the gangrene-like appearance, blue toes may respond to conservative therapy without amputation.
The vein which drains the foot and leg.
Radiography of blood vessels after injection of a contrast medium.
Hospitals organized and controlled by a group of physicians who practice together and provide each other with mutual support.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Endoscopic examination, therapy or surgery performed on the interior of blood vessels.
Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.
Lesions formed within the walls of ARTERIES.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
The hollow, muscular organ that maintains the circulation of the blood.
Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.
The period following a surgical operation.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.
An alternative to amputation in patients with neoplasms, ischemia, fractures, and other limb-threatening conditions. Generally, sophisticated surgical procedures such as vascular surgery and reconstruction are used to salvage diseased limbs.
Drugs used to cause dilation of the blood vessels.
Methods of creating machines and devices.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)
The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.
The tunnel in the lower anterior ABDOMINAL WALL through which the SPERMATIC CORD, in the male; ROUND LIGAMENT, in the female; nerves; and vessels pass. Its internal end is at the deep inguinal ring and its external end is at the superficial inguinal ring.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
A technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure. It may be achieved by intra-aortic balloon, or by implanting a special pumping device in the chest, or externally by applying a negative pressure to the lower extremities during cardiac systole.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Pressure, burning, or numbness in the chest.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
Narrowing below the PULMONARY VALVE or well below it in the infundibuluar chamber where the pulmonary artery originates, usually caused by a defective VENTRICULAR SEPTUM or presence of fibrous tissues. It is characterized by restricted blood outflow from the RIGHT VENTRICLE into the PULMONARY ARTERY, exertional fatigue, DYSPNEA, and chest discomfort.
Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The nonstriated involuntary muscle tissue of blood vessels.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.

The relationship between periprocedural myocardial infarction and subsequent target vessel revascularization following percutaneous coronary revascularization: insights from the EPIC trial. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications. (1/228)

OBJECTIVES: We sought to determine whether periprocedural myocardial infarction complicating percutaneous coronary revascularization is associated with subsequent clinical restenosis, as judged by the need for target vessel revascularization. BACKGROUND: Although myocardial enzyme elevation following angioplasty is associated with increased late mortality, its effect on subsequent clinical restenosis, as assessed by the need for late target vessel revascularization (TVR), is unknown. METHODS: Serial myocardial enzyme determinations were performed on 2,099 patients who underwent angioplasty or atherectomy in the Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications (EPIC) trial. Thirty-day survivors were prospectively followed for three years for adverse clinical events including death and need for TVR. RESULTS: Within the study population, periprocedural creatine kinase (CK) elevation was a predictor of late mortality. Among patients with elevated CK, however, a paradoxical decrease in the need for late TVR was present. This relationship became progressively more profound as the magnitude of CK release increased. Late TVR occurred in 29.8% of patients with no CK elevation, 24.8% with CK elevation to >3 times normal, and 16.9% with >10 times elevation (hazard ratio 0.51, 95% CI 0.29, 0.91). CONCLUSIONS: In the EPIC study, patients with periprocedural MI were less likely to develop clinical restenosis as measured by the need for TVR. Mechanistically, although it is unlikely that CK elevation prevents vascular renarrowing per se, myocardial necrosis impairs the clinical manifestation of restenosis, thereby reducing the need for ischemia-driven TVR. This novel finding 1) highlights the potential discordance between angiographic and clinical measures of restenosis, and 2) has implications for clinical trials, as therapies that reduce periprocedural MI may be associated with a perceived excess of restenosis when measured by the need for TVR.  (+info)

Influence of a platelet GPIIb/IIIa receptor antagonist on myocardial hypoperfusion during rotational atherectomy as assessed by myocardial Tc-99m sestamibi scintigraphy. (2/228)

OBJECTIVES: This study evaluated the effect of the glycoprotein IIb/IIIa (GPIIb/IIIa) antagonist abciximab on myocardial hypoperfusion during percutaneous transluminal rotational atherectomy (PTRA). BACKGROUND: PTRA may cause transient ischemia and periprocedural myocardial injury. A platelet-dependent risk of non-Q-wave infarctions after directional atherectomy has been described. The role of platelets for the incidence and severity of myocardial hypoperfusion during PTRA is unknown. METHODS: Seventy-five consecutive patients with complex lesions were studied using resting Tc-99m sestamibi single-photon emission computed tomography prior to PTRA, during, and 2 days after the procedure. The last 30 patients received periprocedural abciximab (group A) and their results were compared to the remaining 45 patients (group B). For semiquantitative analysis, myocardial perfusion in 24 left ventricular regions was expressed as percentage of maximal sestamibi uptake. RESULTS: Baseline characteristics did not differ between the groups. Transient perfusion defects were observed in 39/45 (87%) patients of group B, but only in 10/30 (33%) patients of group A (p < 0.001). Perfusion was significantly reduced during PTRA in 3.3 +/- 2.5 regions in group B compared to 1.4 +/- 2.5 regions in group A (p < 0.01). Perfusion in the region with maximal reduction during PTRA in groups B and A was 76 +/- 15% and 76 +/- 15% at baseline, decreased to 56 +/- 16% (p < 0.001) and 67 +/- 14%, respectively, during PTRA (p < 0.01 A vs. B), and returned to 76 +/- 15% and 80 +/- 13%, respectively, after PTRA. Nine patients in group B (20%) and two patients in group A (7%) had mild creatine kinase and/or troponin t elevations (p = 0.18). Patients with elevated enzymes had larger perfusion defects than did patients without myocardial injury (4.2 +/- 2.7 vs. 2.3 +/- 2.5 regions, p < 0.05). CONCLUSIONS: These data indicate that GPIIb/IIIa blockade reduces incidence, extent and severity of transient hypoperfusion during PTRA. Thus, platelet aggregation may play an important role for PTRA-induced hypoperfusion.  (+info)

Mechanisms of acute lumen gain and recurrent restenosis after rotational atherectomy of diffuse in-stent restenosis: a quantitative angiographic and intravascular ultrasound study. (3/228)

OBJECTIVES: This quantitative angiographic and intravascular ultrasound study determined the mechanisms of acute lumen enlargement and recurrent restenosis after rotational atherectomy (RA) with adjunct percutaneous transluminal coronary angioplasty in the treatment of diffuse in-stent restenosis (ISR). BACKGROUND: In-stent restenosis remains a significant clinical problem for which optimal treatment is under debate. Rotational atherectomy has become an alternative therapeutic approach for the treatment of diffuse ISR based on the concept of "tissue-debulking." METHODS: Rotational atherectomy with adjunct angioplasty of ISR was used in 45 patients with diffuse lesions. Quantitative coronary angiographic (QCA) analysis and sequential intravascular ultrasound (IVUS) measurements were performed in all patients. Forty patients (89%) underwent angiographic six-month follow-up. RESULTS: Rotational atherectomy lead to a decrease in maximal area of stenosis from 80+/-32% before intervention to 54+/-21% after RA (p < 0.0001) as a result of a significant decrease in intimal hyperplasia cross-sectional area (CSA). The minimal lumen diameter after RA remained 15+/-4% smaller than the burr diameter used, indicating acute neointimal recoil. Additional angioplasty led to a further decrease in area of stenosis to 38+/-12% due to a significant increase in stent CSA. At six-month angiographic follow-up, recurrent restenosis rate was 45%. Lesion and stent length, preinterventional diameter stenosis and amount of acute neointimal recoil were associated with a higher rate of recurrent restenosis. CONCLUSIONS: Rotational atherectomy of ISR leads to acute lumen gain by effective plaque removal. Adjunct angioplasty results in additional lumen gain by further stent expansion and tissue extrusion. Stent and lesion length, severity of ISR and acute neointimal recoil are predictors of recurrent restenosis.  (+info)

Heparin after percutaneous intervention (HAPI): a prospective multicenter randomized trial of three heparin regimens after successful coronary intervention. (4/228)

OBJECTIVES: The purpose of this study was to determine the incidence of bleeding, vascular, and ischemic complications using three different heparin regimens after successful intervention. BACKGROUND: The ideal dose and duration of heparin infusion after successful coronary intervention is unknown. METHODS: Patients were randomized to one of three heparin strategies after coronary intervention: Group 1 (n = 157 patients) received prolonged (12 to 24 h) heparin infusion followed by sheath removal; Group 2 (n = 120 patients) underwent early removal of sheaths, followed by reinstitution of heparin infusion for 12 to 18 h; Group 3 (n = 137 patients) did not receive any further heparin after intervention with early sheath removal. The primary end point of the study was the combined incidence of in-hospital bleeding and vascular events. Secondary end points included in-hospital ischemic events, length of stay, cost and one-month outcome. RESULTS: After successful coronary intervention, 414 patients were randomized. Unstable angina or postinfarction angina was present in 83% of patients before intervention. The combined incidence of bleeding and vascular events was 21% in Group 1, 14% in Group 2 and 8% in Group 3 (p = 0.01). The overall incidence of in-hospital ischemic complications was 2.2%; there were no differences between groups. Length of hospital stay was shorter (p = 0.033) and adjusted hospital cost was lower (p < 0.001) for Group 3. At 30 days, the incidence of delayed cardiac and vascular events was similar for all three groups. CONCLUSIONS: Heparin infusion after successful coronary intervention is associated with more minor bleeding and vascular injury, prolonged length of stay and increased cost. In-hospital and one-month ischemic events rarely occur after successful intervention, irrespective of heparin use. Routine postprocedure heparin is not recommended, even in patients who present with unstable ischemic syndromes.  (+info)

Low prevalence of Chlamydia pneumoniae in atherectomy specimens from patients with coronary heart disease. (5/228)

Coronary atherectomy specimens from 50 patients with coronary heart disease were examined for the presence of Chlamydia pneumoniae by two different methods of polymerase chain reaction (PCR) and by in situ hybridization. C. pneumoniae DNA was detected by PCR in atherosclerotic plaques of four patients (8%). Two patients' coronary atheromas were positive, both by a single-step 16S rRNA-based PCR and by an omp1-based nested PCR. The other two patients' specimens were positive only by the nested PCR. In contrast, C. pneumoniae was not detected by in situ hybridization in any of the cardiovascular tissues tested. Of three patients with evidence of C. pneumoniae in coronary atheromas, two had an antibody titer of 1:32 and the third had no specific antibodies detectable. Results of this study demonstrate a low prevalence of C. pneumoniae DNA in coronary atheromas. These findings do not support the hypothesis that the organism plays a major role in atherogenesis.  (+info)

In vitro examination of the safety of rotational atherectomy of side branches jailed by stents. (6/228)

In vitro experimental models of branch orifices jailed by various stents were created to estimate the safety and the efficacy of rotational atherectomy when rotational burrs were advanced through the struts of stents. The scaffolding structures of the stents were destroyed due to loss and deflection of the struts, and the size of ablated stent-particles differed: the maximal size was 1.7 mm in slotted stents, and 17.6 mm in coiled stents. Thus, there is a definite potential for ablating stents when rotational atherectomy of restenotic lesions of side-branch orifices jailed by stents is performed.  (+info)

Expression of cytokine and adhesion molecule mRNA in atherectomy specimens from patients with coronary artery disease. (7/228)

Coronary arteriosclerosis is an underlying condition in acute myocardial infarction (AMI), unstable angina pectoris (UAP) and stable angina pectoris (SAP), and is also related to restenosis (RS) following coronary intervention. To investigate the pathogenesis of this condition, a quantitative reverse transcriptase polymerase chain reaction was used to determine relative levels of mRNA for interleukin (IL)-1beta, IL-6, IL-8, transforming growth factor beta (TGF-beta), intercellular adhesion molecule (ICAM)-1, E-selectin and vascular cell adhesion molecule (VCAM)-1 using directional coronary atherectomy (DCA) specimens. Eleven patients with AMI, 7 with UAP, 10 with SAP and 6 with RS following a previous coronary intervention underwent DCA. The mRNA intensity for each molecule was expressed by comparing it with that of beta-actin mRNA. The AMI and UAP patients showed high frequencies of mRNA for IL-1beta, IL-8, TGF-beta, and ICAM-1 together with strong intensities of expression, whereas SAP patients showed decreased mRNA expression for these molecules. Increased IL-6 mRNA expression was observed only in AMI samples. Specimens from RS patients revealed an accumulated expression of proinflammatory cytokines, except for IL-6, as well as of TGF-beta. The study suggests that variation in mRNA expression may reflect the pathophysiology of specific types of coronary artery disease, and remodeling following vascular injury.  (+info)

Creatine kinase-MB elevation after coronary intervention correlates with diffuse atherosclerosis, and low-to-medium level elevation has a benign clinical course: implications for early discharge after coronary intervention. (8/228)

OBJECTIVES: The study evaluated the incidence and predictors of creatine kinase-MB isoenzyme (CK-MB) elevation after successful coronary intervention using current devices, and assessed the influence on in-hospital course and midterm survival. BACKGROUND: The CK-MB elevation after coronary intervention predominantly using balloon angioplasty correlates with late cardiac events of myocardial infarction (MI) and death. Whether CK-MB elevation after nonballoon devices is associated with an adverse short and midterm prognosis is unknown. METHODS: The incidence and predictors of CK-MB elevation after coronary intervention were prospectively studied in 1,675 consecutive patients and were followed for in-hospital events and survival. RESULTS: CK-MB elevation was detected in 313 patients (18.7%), with 1-3x in 12.8%, 3-5x in 3.5% and >5x normal in 2.4% of patients. Procedural complications or electrocardiogram changes occurred in only 49% of the CK-MB-elevation cases; CK-MB elevation was more common after nonballoon devices (19.5% vs. 11.5% after percutaneous transluminal coronary angioplasty; p < 0.01). Predictors of CK-MB elevation on multivariate analysis were diffuse coronary disease (p = 0.02), systemic atherosclerosis (p = 0.002), stent use (p = 0.04) and absence of beta-blocker therapy (p = 0.001). Adverse in-hospital cardiac events were more frequent in patients with >5x CK-MB elevation, with no significant difference between 1-5x CK-MB elevation versus normal CK-MB group. During a mean follow-up of 13 +/- 3 months, the incidence of death in the CK-MB-elevation group was 1.6% versus 1.3% in the normal CK-MB group (p = NS). CONCLUSIONS: The CK-MB elevation after coronary intervention was observed even in the absence of discernible procedural complications and was more common in patients with diffuse atherosclerosis. In-hospital clinical events requiring prolonged monitoring were higher in >5x CK-MB-elevation patients only. Midterm survival of CK-MB-elevation patients was similar to those with normal CK-MB. Our prospective analysis shows a lack of adverse in-hospital cardiac events and suggests that early discharge of stable 1-5x normal CK-MB-elevation patients after successful coronary intervention is safe.  (+info)

TY - JOUR. T1 - Evaluation of thrombus removal by transluminal extraction coronary atherectomy by percutaneous coronary angioscopy. AU - Annex, Brian H.. AU - Larkin, Timothy J.. AU - ONeill, William W.. AU - Safian, Robert D.. PY - 1994/9/15. Y1 - 1994/9/15. N2 - Coronary angioscopy was superior to angiography for evaluating the efficacy of thrombus removal after TEC. In patients with acute ischemic syndromes, TEC was effective in removing intraluminal thrombus.. AB - Coronary angioscopy was superior to angiography for evaluating the efficacy of thrombus removal after TEC. In patients with acute ischemic syndromes, TEC was effective in removing intraluminal thrombus.. UR - http://www.scopus.com/inward/record.url?scp=0027971027&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0027971027&partnerID=8YFLogxK. U2 - 10.1016/0002-9149(94)90753-6. DO - 10.1016/0002-9149(94)90753-6. M3 - Article. C2 - 8074047. AN - SCOPUS:0027971027. VL - 74. SP - 606. EP - 609. JO - American ...
TY - JOUR. T1 - Abrupt vessel closure after directional coronary atherectomy. AU - Popma, Jeffrey J.. AU - Topol, Eric J.. AU - Hinohara, Tomoaki. AU - Pinkerton, Cass A.. AU - Baim, Donald S.. AU - King, Spencer B.. AU - Holmes, David R.. AU - Whitlow, Patrick L.. AU - Kereiakes, Dean J.. AU - Hartzler, Geoffrey O.. AU - Kent, Kenneth M.. AU - Ellis, Stephen G.. AU - Simpson, John B.. PY - 1992/6. Y1 - 1992/6. N2 - From October 1, 1986 to December 31, 1989 directional coronary atherectomy was performed during 1,020 procedures (1,140 lesions) at 14 clinical centers. Abrupt vessel closure, defined as a total coronary occlusion or subtotal occlusion associated with clinical evidence of myocardial ischemia, occurred in 43 procedures (4.2%). It developed in the catheterization laboratory in 34 patients, but was delayed 1 to 96 h after directional atherectomy in 9 patients. By univariate analysis the incidence of abrupt closure was higher in directional atherectomy of de novo lesions (p , 0.001), ...
TY - JOUR. T1 - Coronary angioplasty versus excisional atherectomy trial. T2 - CAVEAT. AU - Holmes, David. AU - Garratt, Kirk N.. AU - Topol, Eric J.. PY - 1992/1/1. Y1 - 1992/1/1. KW - Coronary angioplasty. KW - Exasional atherectomy. UR - http://www.scopus.com/inward/record.url?scp=0026575986&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0026575986&partnerID=8YFLogxK. U2 - 10.1016/0167-5273(92)90170-8. DO - 10.1016/0167-5273(92)90170-8. M3 - Editorial. C2 - 1572733. AN - SCOPUS:0026575986. VL - 35. SP - 143. EP - 146. JO - International Journal of Cardiology. JF - International Journal of Cardiology. SN - 0167-5273. IS - 2. ER - ...
Atherectomy led to better postprocedural luminal dimensions but was similar to angioplasty for 6-month outcomes in left anterior descending coronary arteries. Coronary atherectomy, endoluminal stenting, and laser angioplasty are alternative interventions to balloon angioplasty (PTCA) for the percutaneous revascularization of obstructive CAD. They were developed because of the persistent unacceptably high restenosis rate (30% to 50%) associated with PTCA. The Coronary Angioplasty versus Excisional Atherectomy Trial (CAVEAT) by Topol and colleagues and the Canadian Coronary Atherectomy Trial (CCAT) by Adelman and colleagues are important because they are the first randomized trials to compare PTCA with an alternative intervention device. In fact, only 2 other randomized trials with PTCA have been reported: the Angioplasty Compared to Medicine (ACME) trial in patients with single-vessel disease and the Randomized Intervention Treatment of Angina (RITA) trial comparing PTCA with bypass graft ...
Directional atherectomy was associated with a trend toward lower rates of restenosis at 6 months, and increased mortality and ischemic events at one year. DCA resulted in higher rates of early complications at a higher cost and with no clinical benefit. Paradoxically, initial dissemination of these study results produced a transient increase in use of directional atherectomy at CAVEAT-I sites. Among investigators in the trial, there may have been a lack of influence of trial data on clinical practice patterns 1 year after publication of the results.. ...
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TY - JOUR. T1 - Comparative early and nine-month results of rotational atherectomy, stents, and the combination of both for calcified lesions in large coronary arteries. AU - Hoffmann, Rainer. AU - Mintz, Gary S.. AU - Kent, Kenneth M.. AU - Pichard, Augusto D.. AU - Satler, Lowell F.. AU - Popma, Jeffrey J.. AU - Hong, Mun K.. AU - Laird, John R.. AU - Leon, Martin B.. PY - 1998/3/1. Y1 - 1998/3/1. N2 - The aim of this study was to determine the preferred treatment modality for calcified lesions in large (≤3 mm) coronary arteries, resulting in the largest lumen dimensions and the most favorable late clinical responses. Three hundred six lesions in 306 patients (223 men, mean age 66 ± 11 years) were treated with either rotational atherectomy plus adjunct balloon angioplasty (n = 147), Palmaz-Schartz stents (n = 103), or a combination of rotational atherectomy plus adjunct Palmaz-Schartz stents (n = 56). The procedural success rate was 98.0% to 98.6% for each treatment modality. Minimal lumen ...
Fingerprint Dive into the research topics of Balloon postdilation can safely improve the results of successful (but suboptimal) directional coronary atherectomy. Together they form a unique fingerprint. ...
In addition to compressing and reshaping atheroma, atherectomy excises tissue and debulks plaques; it was anticipated that this mechanism would result in a lower rate of restenosis than that occurring after angioplasty. These expectations were not fulfilled in this trial. Although the procedural success rate was somewhat higher and the postprocedure lumen larger in patients treated with atherectomy, lumen dimensions, restenosis rates and clinical outcomes were similar in the two groups at six months. Clinical outcomes for the two groups were similar at up to 18 months after the procedure.. ...
Atherectomy is a minimally invasive endovascular surgery technique for removing atherosclerosis from blood vessels within the body. It is an alternative to angioplasty for the treatment of peripheral artery disease, but the studies that exist are not adequate to determine if it is superior to angioplasty. It has also been used to treat coronary artery disease, albeit ineffectively. Atherectomy is used to treat narrowing in arteries caused by peripheral artery disease. Unlike angioplasty and stents, which push plaque into the vessel wall, atherectomy cuts plaque from the wall of the artery. While atherectomy is usually employed to treat arteries it can be used in veins and vascular bypass grafts as well. Atherectomy falls under the general category of percutaneous revascularization, which implies re-canalizing blocked vasculature via a needle puncture in the skin. The most common access point is near the groin through the common femoral artery (CFA). Other common places are the brachial artery, ...
Rotational atherectomy by rotablator. The rotablator pulverize the calcified plaque of atheroma. Here, example of a coronary artery. - Stock Image C002/7142
BACKGROUND: There is paucity of data regarding the clinical outcome of second generation drug- eluting stents (DES) post rotational atherectomy (RA) for heavily calcified coronary lesions (HCCL). METHODOLOGY: The study cohort comprised 99 (116 lesions) consecutive patients who underwent RA for HCCL at our institution and received either a first generation DES (40 patients, 53 lesions) or a second generation DES (59 patients, 63 lesions). The analyzed clinical parameters were the 12-month rates of death (all cause and cardiac), Q-wave MI, target lesion revascularization (TLR), definite stent thrombosis (ST) and major adverse cardiac events (MACE) defined as the composite of death, Q-wave MI, or TLR. RESULTS: The two groups were well matched for their baseline characteristics except for a lower left ventricular ejection fraction in the second generation DES group (46.0±23.0% vs. 55.0±9.0%; p=0.02). The group receiving second generation DES had more type C lesions (81.0% vs. 58.8%; p=0.01), ...
Background: C reactive protein (CRP), an important serum marker of atherosclerotic vascular disease, has recently been reported to be active inside human atherosclerotic plaques.. Aims: To investigate the simultaneous presence of macrophages, CRP, membrane attack complex C5b-9 (MAC), and oxidised low density lipoprotein (oxLDL) in atherectomy specimens from patients with different coronary syndromes.. Methods: In total, 54 patients with stable angina (SA; n = 21), unstable angina (UA; n = 15), and myocardial infarction (MI; n = 18) underwent directional coronary atherectomy for coronary lesions. Cryostat sections of atherosclerotic plaques were immunohistochemically stained with monoclonal antibodies: anti-CD68 (macrophages), anti-5G4 (CRP), aE11 (MAC), and 12E7 (oxLDL). Immunopositive areas were evaluated in relation to fibrous and neointima tissues, atheroma, and media. Quantitative analysis was performed using image cytometry with systematic random sampling (percentage immunopositive/total ...
Clinical Cases in Coronary Rotational Atherectomy: Complex Cases and Complications This concise practical guide is designed to facilitate the clinical
左主幹部をplatformとするpercutaneous transluminal coronary rotational atherectomyの検討 Procedural Results and 3-Month Outcome of Percutaneous Transluminal Coronary Rotational Atherectomy Requiring the Activation of the Burr in the Left Main Coronary Artery ...
Objectives. The purpose of this study was to examine the proliferative capacity and extracellular matrix synthesis of human coronary plaque cells in vitro.. Background. Common to both primary atherosclerosis and restenosis are vascular smooth muscle cell proliferation and production of extracellular matrix proteins. The applicability to humans of experimental animal models of these processes has been questioned.. Methods. Primary atherosclerotic and restenotic lesions were excised by percutaneous directional coronary atherectomy in 93 patients. Smooth muscle cells were cultivated by an explant technique and identified by their morphology in culture, ultrastructural features under electron microscopy and immunostaining using monoclonal antibodies to smooth muscle cell alpha-actin. Proliferation in secondary culture was assessed with growth curves and the synthesis of collagen and sulfated glycosaminoglycans by the incorporation of 3H-proline and 35S-sulfate, respectively. These studies were also ...
TY - GEN. T1 - Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device. AU - Lovik, Ryan D.. AU - Abraham, John P.. AU - Sparrow, Ephraim M. PY - 2009/12/1. Y1 - 2009/12/1. N2 - In vitro and cadaver experiments, coupled with numerical simulations, were performed to assess the possibility mat orbital atherectomy might cause thermal damage of tissue. The experiments involved debulking operations on a surrogate artery and on the plaque-lined posterior tibial artery of a cadaver. Temperatures and coolant flow rates measured during these experiments enabled a numerical simulation of the debulking of a plaque-lined artery in a living human. The temperature variations from the numerical simulations were used to evaluate a thermal injury index. The resulting values of the index were found to be several orders of magnitude below the threshold value for thermal injury. It is concluded that it is extremely unlikely that the use of an orbital debulking ...
Arteriogram and Atherectomy Baltimore, MD - Minimally Invasive Vascular Center offers Arteriogram and Atherectomy services. Our practice serves Baltimore, MD, Laurel, MD, Silver Spring, MD and the surrounding areas.
Leading interventional cardiologists at The Mount Sinai Hospital are the first in the world to use a newly U.S. Food and Drug Administration (FDA) approveddevicefor the treatment of severely calcified coronary arteries before the placement of a cardiac stent to open a blocked artery.. The new device being used in the Cardiac Catheterization Laboratory at The Mount Sinai Hospital is called the Diamondback 360® Coronary Orbital Atherectomy System. Its spinning electrically powered 1.25 mm diamond-coated crown is located on a thin cardiac catheterization guide wire and works within seconds to reduce the amount of hard calcium buildup in a coronary artery. The small calcium particles sanded from the arterys wall are then naturally discarded from the heart and the body.. The atherectomy system made by Cardiovascular Systems, Inc. was just FDA approved on Oct. 21. It is the first new coronary atherectomy system in more than two decades.. We are excited that we are the first in the world to offer ...
An elongate tubular body extends between a rotatable cutter and a control. The cutter is connected to the control with a rotatable element and has a serrated surface. A vacuum is applied through an annular passage defined between the tubular body and the rotatable element. The control has an indicator that reveals resistance to rotation and/or reduction in flow. Material that has been processed by the cutter is aspirated through the tubular body for disposal. The control enables rotation of the rotatable element only following application of a predetermined level of vacuum.
Boston Scientifics Jetstream atherectomy system has received CE mark for a new in-stent restenosis indication. This indication gives EU physicians another safe and effective treatment option for in-stent restenosis, a disease state that has historically been challenging to treat with traditional therapies, says a Boston Scientific press release.. The indication is supported by data from the Jetstream-ISR feasibility study, in which the device demonstrated a strong safety profile, with zero device-stent interactions. The study included long, complex lesions (62% were TASC C&D). Six-month freedom from target lesion revascularisation was 86.2% with patency at 72%.. ...
cleared coronary balloon on the market-is critical for physicians treating highly complex coronary lesions. As the market leader in coronary atherectomy, the 1.0mm balloon complements our orbital atherectomy system as we continue providing advanced solutions for treating the complex and high-risk indicated patient. At launch, CSI will offer both the 1.0-4.0mm Sapphire II PRO and the 2.0-4.0mm Sapphire® NC Plus non-compliant coronary balloons on a limited basis. The company anticipates that OrbusNeichs full balloon product portfolio will become available in the U.S. throughout 2018 and 2019. About OrbusNeich OrbusNeich is a global pioneer in the provision of life-changing vascular solutions and offers an extensive portfolio of products that set industry benchmarks in vascular intervention. Current products include the worlds first dual therapy stents, the COMBO Plus and COMBO Dual Therapy Stents, together with stents and balloons marketed under the names of Azule®, Scoreflex®, Sapphire® ...
Endovascular Today sat down with a multidisciplinary panel of esteemed interventionists to discuss their current practice paradigms for atherectomy, including the hot topic of Vessel Prep prior to drug-coated balloons and other adjunctive therapies.
Cardiovascular Systems, Inc., based in St. Paul, Minn., is a medical device company focused on developing and commercializing innovative solutions for treating vascular and coronary disease. The companys Orbital Atherectomy Systems treat calcified and fibrotic plaque in arterial vessels throughout the leg and heart in a few minutes of treatment time, and address many of the limitations associated with existing surgical, catheter and pharmacological treatment alternatives. The U.S. FDA granted the first 510(k) clearance for the use of the Orbital Atherectomy System in peripheral arteries in August 2007. In October 2013, the company received FDA approval for the Coronary Orbital Atherectomy System. To date, over 356,000 of CSIs devices have been sold to leading institutions across the United States.
In February 2021, Cardiovascular Systems, Inc. (CSI) announced that PT. Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Indonesia.. Bio-Excel (Australia) Pty. Ltd.:. →Australia. In March 2021, Cardiovascular Systems, Inc. (CSI) announced that Bio-Excel Co. Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia.. RSK Medical Inc.. →Canada. In April 2021, Cardiovascular Systems, Inc. (CSI) announced that RSK Medical Inc. signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada.. ...
Is there a difference in the mechanisms of lumen enlargement with direct stenting as compared to stenting with predilatation? A 3D intravascular ultrasound ...
Ease of use has dictated the destiny of all new techniques and devices in interventional cardiology. The popularity of stents began when they became as easy to use and more predictable than balloons. Conversely, directional and rotational atherectomy fell into oblivion or became confined to a small niche application. Some of these devices have been underused, even when proved beneficial, such as filters in saphenous vein graft treatment or thrombectomy in acute myocardial infarction. For chronic total occlusions (CTOs), the only route to success passes through the use of multiple dedicated wires, guided by contralateral injection, and of over-the-wire (OTW) balloons or microcatheters, sometimes inserted retrogradely via collateral vessels with the use of devices with exotic names like Tornus and Corsair (Asahi Intecc, Nagoya, Japan).. No wonder few interventionalists have ventured into this uncharted territory. The problem is, however, that CTOs are very frequent and are present in ,30% of ...
Introduction Rotational atherectomy (RA) during primary PCI (PPCI) for STEMI is relatively contraindicated because of the perceived increased risk of no-reflow. However, RA PPCI may sometimes be required to restore flow in heavily calcified coronary arteries. Previously only very limited observational data has described the use of RA in PPCI. Aim We report the clinical and procedural characteristics, and in hospital outcomes, of 21 patients who underwent RA PPCI at our centre between 2006 and 2016,. Methods A retrospective review of the PCI database and medical records.. Results 21 patients (age 78(10) years (mean (SD)), 12 men) underwent RA during PPCI (0.4% of all PPCI). 3 patients had cardiogenic shock at presentation and 2 had out of hospital cardiac arrest. Hypertension (n=19), smoking history (n=18), hypercholesterolemia (n=16), diabetes (n=6) and chronic kidney disease (n=6 with eGFR ,60) were frequently present. Aspirin was given to 20/21 patients and clopidogrel, ticagrelor and ...
Coronary lesions with severe (or heavy) calcification are classified as complex lesions and are known to carry lower success rates and higher complication rates following percutaneous coronary intervention. The Diamondback 360(®) Coronary Orbital At
Stents have emerged as one of the major therapeutic tools for percutaneous intracoronary revascularization procedures. In fact, a stent is implanted in at least 30% of lesions attempted. Their clinical impact is huge because stenting has produced a decrease int the need for emergency surgery to 0.5%, with an incidence of acute myocardial infarction related to angioplasty of 2% and a death rate of , 1% despite unfavourable clinical and anatomical conditions treated. The initial price of stenting was a high frequency of subacute stent thrombosis and peripheral vascular complications, which has been solved ...
TemREN is used to prepare the lesion area for balloon angioplasty and to relieve heavy plaque burden from atherosclerotic lesions. TemREN is usually made up of art...
Insights from the authors on removing severe superficial calcium to achieve significant luminal gain in femoropopliteal arteries.
EMEA (Europe, Middle East, Africa). In July 2018, Cardiovascular Systems, Inc. (CSI®) announced that OrbusNeich Medical Co. Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems outside the United States and Japan.. Medikit Co., Ltd:. →Japan. In November 2016, Cardiovascular Systems, Inc. (CSI®) announced that Medikit, Co., Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan.. ...
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The industry’s most complete portfolio of PCI products. Learn more about coronary stents, guidewires, atherectomy and more.
Looking for online definition of coronary atherectomy in the Medical Dictionary? coronary atherectomy explanation free. What is coronary atherectomy? Meaning of coronary atherectomy medical term. What does coronary atherectomy mean?
Medtronic has been granted CE mark approval for the HawkOne directional atherectomy system in a lower profile size for treating patients with peripheral artery disease. The new HawkOne 6 Fr provides an effective and easy-to-use treatment option for patients with peripheral artery disease both above and below the knee with a single device. The HawkOne system is designed to remove plaque from the vessel wall and restore blood flow.. Directional atherectomy is an established treatment modality for patients with complex peripheral artery disease to restore patency, maximise luminal gain and preserve future treatment options, says Thomas Zeller, head, Department of Angiology, Universitäts-Herzzentrum Freiburg, Bad Krozingen, Germany. The new smaller HawkOne 6Fr size is an advanced option to treat patients with multi-level peripheral artery disease, addressing lesions of various length, morphology, and location, particularly those below the knee.. The HawkOne system is also designed to enable ...
However, being able to visualize the vessel with the lumivascular technology is clearly appealing and suggestive of safe passage. Distal embolization remains a major concern (especially atherectomy for ISR), and questions the need for embolic protection every time (filter was used only in 22% of patients in the DEFINITVE LE trial).7 Unprecedented complications can arise, which require expertise and catheter skills and may lead to the possibility of open vascular surgery in these high-risk patients.. DA in ISR lesions have been contraindicated due to the potential risk of cutter entrapment on stent struts during atherectomy. However, with the advent of concurrent imaging during DA, this risk can potentially be avoided. Nevertheless, as seen in this case, despite adequate visualization with OCT imaging, there can be significantly malapposed stent struts in overlapped segments that may still pose a risk for trapping the DA catheter. In such scenarios, the use of adjunctive balloon angioplasty ...
A rotational atherectomy device for removing a stenotic tissue from a vessel of a patient is disclosed. The device comprises a rotatable, flexible, hollow drive shaft having a fluid impermeable wall defining a fluid impermeable lumen of the drive shaft and, an abrasive element mounted to a distal end portion of the drive shaft proximal to and spaced away from a distal support element formed at a distal end of the drive shaft, the distal support element being inflatable by pressurized fluid which flows in an antegrade direction through said lumen of the drive shaft and is at least partially re-directed into the distal fluid inflatable support element. The distal fluid inflatable support element has an outer wall comprising an outflow opening located such that said outflow opening faces an inner surface of a treated vessel during rotation of the drive shaft so that a flow of fluid through said outflow opening forms a layer of fluid between the outer wall of the rotating fluid inflated distal support
An atherectomy device is used for removing a restriction in a blood vessel. The atherectomy device includes a cutting portion having a lumen therein, the lumen being sized to track over a guidewire, wherein an outer surface of the cutting portion comprises a cutting surface. An elongate shaping member is cooperable with the cutting portion and is disposed generally longitudinally relative to the cutting portion. The shaping member has an insertion conformation and an expanded conformation. The expanded conformation is radially expanded relative to the insertion conformation. The shaping member is configured to deform the cutting portion from an insertion shape into a cutting shape as the shaping member moves from the insertion conformation to the expanded conformation. A drive shaft is coupled to a proximal end of the cutting portion and is configured to be rotationally driven.
The global Orbital Atherectomy Device Market report provides an accurate investigation of the different patterns and parameters affecting the industrial growth of the Orbital Atherectomy Device market at a global level. An assessment of the effect of the current situation and trends in the market is additionally included to provide an overview of the markets future position. The report provides the detailed information related to the global Orbital Atherectomy Device market dynamics and demonstrates superior forecast for the development of the market and its key competitors Medtronic (Ireland), Philips (Netherlands), Boston Scientific (US), Cardiovascular Systems (US), Straub Medical (Switzerland), BIOTRONIK (Netherlands), C.R. Bard (US), Avinger (US) based on consistent information.. Apply here for the sample copy of the report @: www.99strategy.biz/request-for-sample.html?repid=46491. Furthermore, The report presents a detailed segmentation Peripheral Vascular, Cardiovascular, ...
The incidence of coronary artery disease requiring coronary intervention in patients with Kawasaki disease is high. Because coronary artery lesions in Kawasaki disease commonly involve severe calcification and aneurysmal changes which can progress with time, in contrast with adult atherosclerotic coronary artery lesions, the indication or technique of catheter intervention for adult patients cannot be directly applied. However, the experience of coronary intervention in Kawasaki disease is extremely limited compared to that with intervention in adults, which provides satisfactory therapeutic results. There are several kinds of percutaneous coronary intervention techniques in Kawasaki disease including balloon angioplasty, stent implantation, rotational ablation, and directional coronary atherectomy. Satisfactory acute results for coronary balloon angioplasty can be obtained in patients in a relatively short interval from the onset of disease, especially within 6 years. However, the incidence of ...
This medical exhibit illustrates the Atherectomy Procedure. The atherectomy instrument is visualized within the coronary artery shaving away the atherosclerotic plaque .
An atherectomy apparatus and method is disclosed for the purpose of surgical excision of atheromas which typically consist of plaque deposits that cause narrowing (stenosis) of an artery. The apparatus, called a pullback atherectomy catheter, cuts and collects obstructive material into a collection chamber as the catheter is pulled back through obstructive material within a human vessel such as an artery.
The Global Atherectomy Devices Market is expected to reach USD 894.69 million by 2025, based on a new report by Hexa Reports. The demand for atherectomy de
Data are mean value ± SD, unless otherwise indicated. ANOVA = analysis of variance; CSA = cross-sectional area; EEM = external elastic membrane; P+M = plaque plus media; Δ = change in.. ...
Figure 1 Coronary Angiogram and Intravascular Ultrasound Images of the Left Coronary System. (A) Pre-procedural angiogram demonstrating a restenosed 3.5 × 15-mm Palmaz-Schatz stent (Cordis, Johnson & Johnson Company, Warren, New Jersey) (dotted line) implanted 20 years ago on the proximal LAD and a long segment of calcified disease extending from the LMS to the distal LAD, with involvement of the LAD/diagonal bifurcation (arrows). (B) Angiogram after rotational atherectomy with 1.5-mm burr and aggressive pre-dilation with 3.0- to 3.5-mm noncompliant balloons on LAD. A 2.25 × 12-mm EES in the diagonal ostium with crushed protruding EES struts (dotted line). (C) Intravascular ultrasound showing lumen area of 3.2 mm2 with a vessel diameter of 4.8 mm at the distal LMS. (D) Palmaz-Schatz stent struts (arrowheads) with evident dissection in the restenosed segment (arrows). (E) Cracked napkin-ring calcification after rotational atherectomy and pre-dilation (arrows). (F) Crushed EES struts on to the ...
ECCENTRIC ABRADING HEAD FOR HIGH-SPEED ROTATIONAL ATHERECTOMY DEVICES - The invention provides a rotational atherectomy device having, in various embodiments, a flexible, elongated, rotatable drive shaft with at least one flexible eccentric enlarged abrading head attached thereto. In other embodiments, the eccentric abrading head is not flexible or partially flexible. At least part of the eccentric enlarged cutting head has a tissue removing surface-typically an abrasive surface. In certain embodiments, the abrading head will be at least partially hollow. When placed within an artery against stenotic tissue and rotated at sufficiently high speeds the eccentric nature of the enlarged cutting head causes the cutting head and drive shaft to rotate in such a fashion as to open the stenotic lesion to a diameter substantially larger than the outer diameter of the enlarged cutting head. Preferably the eccentric enlarged cutting head has a center of mass spaced radially from the rotational axis of the ...
A vascular catheter includes a flexible catheter body having proximal and distal ends and an elongate housing secured to the distal end of the catheter body. An interactional device is disposed on one side of the housing, and at least two spaced-apart inflatable chambers are located on the other side of the housing generally at its proximal and distal ends, respectively. The inflatable chambers may be expanded simultaneously or separately, and the spaced-apart positioning of the chambers provides for stable positioning of the housing during atherectomy procedures, imaging procedures, and the like. The balloon is conveniently connected to the housing by an integral flange structure which is secured through an inflation aperture on the housing side. The balloon may be inflated through an annular inflation which is defined by a separate isolation tube disposed in the central lumen of the catheter body.
CPT Code 0264T, Category III Codes, Atherectomy (Open or Percutaneous) for Supra-Inguinal Arteries and Other Undefined Category Codes - Codify by AAPC
An atherectomy system for cutting, ingesting and removing an obstruction from within a patients artery, comprising a flexible guide-wire insertable into the artery, a flexible rotary-catheter rotatably disposed and slidable over the flexible guide-wire, a blade forming a distal end of the flexible rotary-catheter having teeth on its periphery which are bent inward, a continuous passage for ingesting the cut obstruction material between the flexible rotary-catheter and the flexible guide-wire, means at the proximal end of the flexible rotary-catheter for rotating it and positive displacement pump means connected to the continuous passage to pull the cut obstruction material proximally.
Press release - Market Expertz - Atherectomy Devices Market Size, Share Growth, Trends, Devices, Applications, Competitive Analysis, Industry Expansion Strategies, By 2027 - published on openPR.com
Disclosed is a device for delivering tissue adhesives and/or sealant patches to a surface which covers or surrounds a lumen, cavity or organ, or potential lumen or cavity, within a human or other animal. Also disclosed is a method of delivering tissue adhesives and/or sealant patches to a surface which covers or surrounds a lumen, cavity or organ, or potential lumen or cavity. The method is particularly suited to sealing perforations in vascular walls, such as after arterial access for Percutaneous Transluminal Coronary Angioplasty (PTCA), Percutaneous Coronary Angiography and Percutaneous Coronary Atherectomy and similar diagnostic and therapeutic procedures.
Alpesh R. Shah, MD is a Associate Professor of Clinical Cardiology, Academic Institute at Houston Methodist and Weill Cornell Medical College - specializing in Peripheral arterial disease, Valvular heart disease, Angioplasty, Coronary stenting, Carotid artery stenting, Cardiac catherization, Coronary atherectomy, Coronary brachytherapy, Complex coronary interventions, Renal artery stenting. Dr. Shah has been a primary investigator of more than 20 clinical trials at Houston Methodist Hospital. Over the last decade, he has been involved with several clinical trials advancing new stent design and its wider clinical applications. Currently he is involved in clinical research for the Bioabsorbable stent in Coronary arteries. Such devices have the potential of promoting vascular healing by preventing long term neoatheresclerosis and restoring vasomotion. Dr. Shah is an integral part of the Heart Team at Houston Methodist Hospital which continues to look at optimizing outcomes of stenting vs. bypass surgery.
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Despite advances in experience and equipment, CTO recanalization with the use of contemporary guidewires and techniques may still be unsuccessful in ≥25% of cases. Numerous devices have been developed to approach such refractory and complex cases. Many of these devices never progressed beyond the investigational phase because their use in small numbers of patients demonstrated either excessively high rates of complications (typically either dissection and/or perforation) or success rates not clearly greater than those achieved by standard equipment. Examples of failed CTO devices include the Magnum/Magnarail system,38,39 the Kensey Catheter,40 the ROTACS Low Speed Rotational Atherectomy Catheter,41 and the Excimer Laser Wire.42. Two devices specifically designed for refractory CTO recanalization have demonstrated sufficient safety and efficacy to have received approval by the Food and Drug Administration for sale in the United States: the Safe Cross-RF guidewire and the Frontrunner catheter. ...
Yet another embodiment is a rotational atherectomy system, comprising: an elongated, flexible drive shaft having a distal end for insertion into a vasculature of a patient and having a proximal end opposite the distal end remaining outside the vasculature of the patient; an eccentric solid crown attached to the drive shaft proximate the distal end of the drive shaft; an electric motor rotatably coupled to the proximal end of the drive shaft, the electric motor being capable of rotating the drive shaft in a first direction and in a second direction opposite the first direction; and control electronics for monitoring and controlling the rotation of the electric motor. The drive shaft and eccentric solid crown, when rotating, have a torque limited by a current supplied to the electric motor. The control electronics include an algorithm that detects and controls when the drive shaft and eccentric solid crown encounter a blockage in the vasculature that rapidly slows their rotation. The control ...
Cardiovascular Systems (CSI), a provider of orthopedic solutions, is set to exhibit 12-month data from its Compliance 360° study. The prospective, randomized trial, which enrolled 50 patients, was designed to compare the treatment of above-the-knee calcified lesions using the companys Diamondback orbital atherectomy system, followed by low-pressure balloon angioplasty, to balloon angioplasty alone.. The study examines whether Diamondback orbital atherectomy system can achieve satisfactory acute and long-term results without the need for stent placement.. The Diamondback system is used as a minimally invasive therapy to treat patients with peripheral arterial disease (PAD), blockages in leg arteries.. The company said it will present data at the american college of cardiologys (ACCs) 61st annual scientific session & expo McCormick place south in Chicago from 24-27 March 2012.. ...
48 hours postoperatively. One case remained after hospital discharge with monoplegia and dyslalia. One patient had peripheral vascular complications at the site of arterial cannulation with thrombosis, which required embolectomy and raffia with a bovine pericardial patch at the second day after surgery. These complications occurred only in cases of aortic valve replacement in patients with severe stenosis and calcification of annulus and leaflets.. One patient underwent reoperation for mitral stenosis, pulmonary hemorrhage on the fourth postoperative day, after discharge from the ICU and was managed, again in the ICU, with mechanical ventilation. Another patient had pulmonary hemorrhage on discharge from the operating room, probably secondary to complications of selective cannulation, which occurred at 3rd postoperative day. Five (4.8%) patients underwent reoperation for bleeding, all through smaller incisions, only with the help of videoendoscopy.. Five patients, all of the group GcCPB, died ...
A technique for ablation and removal of plaque deposits from the arterial, venous, vascular graft or other tissue wall of a patient. Ablation is accomplished by directing a high pressure jet of sterile saline solution at the plaque deposit. The high pressure jet is located at the distal end of a catheter which is advanced through the vascular system to the site of the plaque deposit. Removal of the debris is via an evacuation lumen within the catheter. The arterial wall is protected from damage by the catheter design which directs the high pressure jet towards a portion of the distal end of the catheter which serves as a target. The distal end of the catheter is placed such that the plaque or other deposit to be ablated is positioned between the high pressure jet and the target. An optional ultrasonic transducer array located adjacent the high pressure jet and the evacuation lumen permits the attending physician to monitor the procedure. A balloon may be used to hold the catheter against the deposit
An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the di
In the hands of experienced cardiologists, and with availability of modern day technology, it is estimated that the risk of death is during a stent procedure is usually less than 1%, while the chance of requiring emergency bypass surgery is around 2% or less. It is a relatively safe procedure and is carried out all over the world. An out patient or an inpatient uncomplicated stent case usually require 23 hours or less of hospitalization after the procedure.. The risk of a other serious complication is estimated to be less than 4 and probably around 1 to 2 per thousand, and similar to that described for cardiac cath. The risk of a heart attack and bleeding that requires a blood transfusion is increased when compared to cardiac cath. However, the risks are relatively low and acceptable in most cases when one balances the potential benefit against the expected risk (risk-benefit ratio).. The aggravation of kidney function (particularly in diabetics and those with prior kidney disease) is higher ...
Rex Medical of Conshohocken, Pennsylvania won regulatory approval from the FDA to sell its Cleaner Rotational Thrombectomy System. The atherectomy system
It looks like a miniature football and spins faster than one of Randall Cunninghams tosses -- up to 190,000 revolutions per minute.But then the device, a new surgical tool called a Rotablator, must
The only caveat is that this is good for people who are already healthy. If you have metabolic problems then this is bad advice. I am pre-diabetic. If I eat 500 g of carbs a day, my insulin…
DISCONTINUED BY MANUFACTURER OR DISCONTINUED PRODUCT. FOR YOUR INFORMATION PURPOSES, WE HAVE KEPT THIS ITEM PLACEMENT AS COURTESY TO OUR CUSTOMERSYou may...
nice guy, but seems to have an unstable disposition to the point that I would not do business with him or recommend that others do so. I dont think hes dishonest, and this rating is not set in stone. If I (passively) observe positive changes in his behavior, this rating will improve. For now, caveat creditor ...

No data available that match "atherectomy coronary"


Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems ... signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia. ...
Coronary atherectomy / rotablation. *Coronary balloon angioplasty including coronary stenting. *Percutaneous transvenous mitral ...
Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems ... signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia. ...
Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems ... signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia. ...
Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems ... signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia. ...
Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems ... signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia. ...
Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems ... signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia. ...
Revass Utama Medika signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems ... signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. ... signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Australia. ...
iDatas global atherectomy device market MedCore covers both the peripheral atherectomy market and the coronary atherectomy ... Laser Atherectomy, Mechanical Atherectomy), Indication (Coronary, Peripheral) ... Coronary Stent Market, Coronary Balloon Catheter Market, Introducer Sheath Market, and 12 more ... Atherectomy Market Size, Share, Trends & COVID19 Impact Analysis , Global , 2021-2027 , MedCore , Segmented by: Product Type ( ...
Live case on patient with severely calcified coronary lesions. Cardiology / Coronary / Live Case/8 Comments ... Intensive plaque modification with rotational atherectomy and cutting balloon before DES implantatio... ...
keywords = "Atherectomy, Calcified lesions, Coronary, Drug-eluting stents, Intervention, Percutaneous, Rotational",. author = " ... Aims: The aim of this multicentre study was to investigate the in-hospital and midterm outcomes of rotational atherectomy (RA) ... N2 - Aims: The aim of this multicentre study was to investigate the in-hospital and midterm outcomes of rotational atherectomy ... AB - Aims: The aim of this multicentre study was to investigate the in-hospital and midterm outcomes of rotational atherectomy ...
Global Percutaneous Transluminal Coronary Angioplasty (PTCA)… $ 5450 April 2021 Global Clot Management Devices Industry $ 4950 ... Global Atherectomy Devices Industry $ 5450 April 2021 Global Embolic Protection Devices Industry $ 4950 April 2021 ...
PTCA - Coronary Stenting. *Rotational Atherectomy. *Transesophageal Echocardiography. Professional Affiliations Professional ...
Coronary Stents. *Deep Venous. *Directional Atherectomy Systems. *Drug-Coated Balloons. *Embolic Protection Devices ...
Complex Coronary Atherectomy Case: Double Jeopardy!: Valery S. Effoe, MD, MS - Cardiology Fellow , Morehouse School of Medicine ... Percutaneous Coronary Intervention for Left Main Disease in a Patient with CoronaryAneurysm and history of Kawasaki Disease: ... Leave Nothing Behind: The Role of Drug Eluting Balloon After an Orbital Atherectomy: Chan Ho Thum, MBBS - Cardiology Fellow , ... High-Risk and Indicated Percutaneous Coronary Interventions , Henry Ford Hospital ...
Experience of Percutaneous Coronary Intervention for Severely Calcified Coronary Artery Lesions with Orbital Atherectomy System ...
ELCA Coronary Laser Atherectomy Catheter Vitesse- E-RX Laser Ablation Catheter - 1.7mm x .065 x 135cm 1.7mm x .065 x 135cm ... ELCA Coronary Laser Atherectomy Catheter 1.7mm Vitesse-Cos RX- 1.7mm x 135cm 1.7mm x 135cm ... ELCA Coronary Laser Atherectomy Catheter - 2.0mm Vitesse-Cos RX - 2mm x 135cm 2mm x 135cm ... ELCA Excimer Laser Coronary Atherectomy MAX Guidewire - .014-Non-Expired 1.4mm x 135cm ...
... listing the rotational atherectomy systems ROTAPRO and ROTALINK PLUS of the company Boston Scientific under Title V of the list ... Mini-HTA for coronary sinus reducer stent in refractory angina pectoris treatment released in Norway ... In October 2020, a completed mini-method assessment for the coronary sinus reducer stent (Neovasc) implantation in refractory ... Non-invasive diagnostics in case of suspected coronary artery disease assessed by IQWiG in Germany ...
Excimer laser coronary atherectomy (ELCA) is a long-established adjunctive therapy that for some Interventional Cardiologists, ... How does laser atherectomy work and what is the learning curve to using it in coronaries? ... Coronary physiology assessment now has a tremendous level of clinical data to support its use in todays cath lab, but ... Is there a learning curve to using laser atherectomy?. Dr. Kevin Croce from Brigham and Womens Hospital in Boston gives a ...
Coronary Atherectomy. *Experimental Treatment. *Infections. *Intubation Delay. *Invasive Procedures. *Lasik Eye Surgery ...
Atherectomy is a surgical procedure to remove a buildup of fat, cholesterol, and other substances (plaque) from the inside of ... You may have this procedure to remove plaque from the arteries of your heart (coronary arteries). You can also have this ... What is Atherectomy. Atherectomy is a surgical procedure to remove a buildup of fat, cholesterol, and other substances (plaque ... An atherectomy is a surgical procedure to remove a buildup of fat, cholesterol, and other substances (plaque) from the inside ...
Experience of Percutaneous Coronary Intervention for Severely Calcified Coronary Artery Lesions with Orbital Atherectomy System ... Patient Radiation Exposure During Primary Percutaneous Coronary Intervention in Acute ST-elevation Myocardial Infarction at the ...
Experience of Percutaneous Coronary Intervention for Severely Calcified Coronary Artery Lesions with Orbital Atherectomy System ... Patient Radiation Exposure During Primary Percutaneous Coronary Intervention in Acute ST-elevation Myocardial Infarction at the ...
Experience of Percutaneous Coronary Intervention for Severely Calcified Coronary Artery Lesions with Orbital Atherectomy System ...
Experience of Percutaneous Coronary Intervention for Severely Calcified Coronary Artery Lesions with Orbital Atherectomy System ... Patient Radiation Exposure During Primary Percutaneous Coronary Intervention in Acute ST-elevation Myocardial Infarction at the ... Study on Clinical Profile and Optical Coherence Tomography-guided Management Strategy for Patients with Young Acute Coronary ...
Experience of Percutaneous Coronary Intervention for Severely Calcified Coronary Artery Lesions with Orbital Atherectomy System ...
Experience of Percutaneous Coronary Intervention for Severely Calcified Coronary Artery Lesions with Orbital Atherectomy System ... Patient Radiation Exposure During Primary Percutaneous Coronary Intervention in Acute ST-elevation Myocardial Infarction at the ... Overcoming the Complexities of Coronary Intervention - Contemporary PCI in LM Disease Series ...
Table 48: Second Generation Diamondback 360 Coronary Orbital Atherectomy System - Product Status. Table 49: Second Generation ... Table 51: Second Generation Diamondback 360 Coronary Orbital Atherectomy System - Evaluation of Treatment Strategies for Severe ... Table 22: Coronary Angio Catheter - Product Status. Table 23: Coronary Angio Catheter - Product Description. Table 24: Avantec ... Table 25: Specialty Coronary Catheter - Product Status. Table 26: Specialty Coronary Catheter - Product Description. Table 27: ...
The rotational atherectomy catheter is introduced into the coronary artery over a dedicated long rotational atherectomy wire, ... Rotational atherectomy is a technique used to treat calcified (hardened) lesions causing significant blockages in coronary ... RotaPro™ is the newest atherectomy innovation from Boston Scientific that is easier to use, faster to set up and more intuitive ... After successful rotational atherectomy, the procedure is completed with conventional balloon angioplasty and stent placement. ...
... signed an exclusive distribution agreement with Medikit to sell its Diamondback 360 Coronary and Peripheral Orbital Atherectomy ... Directional atherectomy prior to IN.PACT DCB effective out to one year,.... 7th November 2020. ... Outpatient atherectomy outcomes may be "worse than the natural history of.... 7th August 2017. ... Atherectomy for occlusive disease in the femoral-popliteal and tibial-peroneal segments for claudication in outpatient settings ...
  • Avinger, a developer of treatments for peripheral artery disease (PAD), has announced the first use of their next generation Pantheris lumivascular atherectomy system. (vascularnews.com)
  • The most common cause of HF is coronary artery disease (CAD), including the acute coronary syndromes (ACS) of ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), and unstable angina (UA) [ 2 ]. (biomedcentral.com)
  • IVL has very high levels of safety and effectiveness across multiple clinical studies involving severely calcified coronary and peripheral artery disease. (shockwavemedical.com)
  • Immunosuppressive oral prednisone after percutaneous interventions in patients with multi-vessel coronary artery disease. (pcronline.com)
  • General description of procedure, equipment, technique Introduction Following the introduction of balloon angioplasty as treatment for obstructive coronary artery disease, it became quickly evident that this procedure was associated with two major problems-acute closure of the vessel and chronic restenosis. (pulmonologyadvisor.com)
  • This minimally invasive procedure can improve blood flow if you experience peripheral vascular disease or coronary artery disease . (umiamihealth.org)
  • Cardiovascular Systems announced today that the first patient in Europe has been treated with its Stealth 360 peripheral orbital atherectomy system (OAS) 1.25mm Micro. (vascularnews.com)
  • Dr. Jacobson's special clinical interests include pacemaker implantations, carotid artery stenting, and complex coronary interventions, including angioplasty and stenting of chronic total occlusions. (memorialcardiologyassoc.com)
  • The patient-level pooled analysis of the four prospective Disrupt CAD studies (Disrupt CAD I, II, III, and IV) analyzed the clinical outcomes of coronary IVL in severely calcified, stenotic de novo coronary arteries prior to stenting. (shockwavemedical.com)
  • Catheter-induced Aortic Dissection During Coronary Stenting - Surgery or Intervention? (complex-pci.com)
  • Assessment of Loading With the P2Y12 Inhibitor Ticagrelor or Clopidogrel to Halt Ischemic Events in Patients Undergoing Elective Coronary Stenting. (heart.org)
  • Methods and results: Between 2002 and 2013, 1,176 de novo lesions with calcified coronary lesions treated by RA and metallic stent implantation at nine institutions were assessed. (elsevier.com)
  • Rotational atherectomy is a technique used to treat calcified (hardened) lesions causing significant blockages in coronary arteries to facilitate coronary stent implantation. (coscardio.ie)
  • Moderate to severely calcified lesions account for about a third of significant coronary artery blockages and can be very challenging to treat with balloon angioplasty alone. (coscardio.ie)
  • Coronary IVL showed low rates of major adverse cardiovascular events (MACE) and very low rates of severe angiographic complications in complex target lesions. (shockwavemedical.com)
  • In the treatment of severely calcified lesions, IVL offers several advantages compared to balloon-based and athero-ablative (atherectomy) technologies. (shockwavemedical.com)
  • After successful rotational atherectomy, the procedure is completed with conventional balloon angioplasty and stent placement. (coscardio.ie)
  • A vessel preparation treatment strategy of directional atherectomy prior to drug-coated balloon angioplasty with Medtronic's IN.PACT Admiral drug-coated balloon (DCB) in long, calcified femoropoliteal. (vascularnews.com)
  • Follow step-by-step recommendations using angiography or intravascular imaging for treatment using balloon angioplasty, atherotomy, or atherectomy before provisional or dual-stent techniques from our BifurcAID app based on lesion and vessel morphology. (cardiologyapps.com)
  • These minimally-invasive outpatient procedures include peripheral angioplasty and arterial stents, atherectomy, varicose vein removal and angiograms. (heartvascular.net)
  • An atherectomy is an alternative to angioplasty. (heartvascular.net)
  • Atherectomy is most commonly used if you have already had a balloon angioplasty or stent placed, but still have poor blood flow. (umiamihealth.org)
  • Over the years, a variety of devices have been used to open occluded vessels, including high pressure angioplasty balloons, specialty angioplasty balloons with wires or blades wrapped around the balloon, and atherectomy devices that debulk or remove plaque. (ceocfobulletin.com)
  • A 79-year-old diabetic male patient with no history of coronary disease is referred to you to undergo angioplasty for tissue loss on the tips of the hallux and second toe. (vascupedia.com)
  • He specializes in management of advanced cardiac disease and interventional cardiology, including rotational atherectomy, cardiac catheterization, coronary stent placement, echocardiography, stress echocardiography and pacemakers. (tmphysiciannetwork.org)
  • The rotational atherectomy catheter is introduced into the coronary artery over a dedicated long rotational atherectomy wire, which consists of a monofilament stainless steel 0.09-inch wire with a floppy, curveable spring coil tip, which is 0.11 inch. (coscardio.ie)
  • RD Global-Invamed has announced it has received CE marking to market the Extender drug-coated balloon (DCB) and Temren atherectomy with CTO catheter for treating. (vascularnews.com)
  • In this procedure, a high-speed instrument - rotary shaver- called burr, is placed at the tip of the catheter and is used to cut through a heavily calcified plaque to reopen a blocked coronary artery. (ckbirlahospitals.com)
  • An atherectomy is a procedure that utilizes a catheter with a sharp blade on the end to remove plaque from a blood vessel. (demanddeborah.org)
  • An educational tool, the BifurcAID app helps guide and teach interventional cardiologists the different techniques of coronary bifurcation interventions, in a step by step manner. (cardiologyapps.com)
  • Clin Prof Koh has extensive experience in interventional techniques, including the use of atherectomy and valvuloplasty procedures with a special interest in acute myocardial infarction interventions. (nhcs.com.sg)
  • Dr. Awar's clinical interests include treatment of coronary and vascular disease and he specializes in performing heart catheterizations through the wrist (radial approach) in order to enhance patient comfort and safety. (memorialcardiologyassoc.com)
  • CalcificAID guides medical professionals through the treatment of coronary calcification. (cardiologyapps.com)
  • The device, Avinger's Pantheris™ lumivascular atherectomy system, is an innovative image-guided therapy which, for the first time ever, allows physicians to see and remove plaque simultaneously during atherectomy - a minimally invasive procedure that involves cutting plaque away from the artery and clearing it out to restore blood flow. (demanddeborah.org)
  • It remains to be seen whether IVUS-detected attenuated plaques is associated with only transient deterioration in coronary flow during PCI (18) or an adverse long term clinical outcome. (healthyfutureforkids.com)
  • Also, one clinical guidance (for acute coronary syndromes) was updated. (mtrconsult.com)
  • Heart failure (HF) is a serious complication of acute coronary syndromes (ACS), and is associated with high in-hospital mortality and poor long-term survival. (biomedcentral.com)
  • The study was selected from the Gulf Registry of Acute Coronary Events (Gulf RACE), a prospective multi-national, multicenter registry of patients hospitalized with ACS in six Middle East countries. (biomedcentral.com)
  • Coronary IVL was consistently effective in achieving high acute gain and low residual stenosis. (shockwavemedical.com)
  • His main interests in the field of interventional cardiology include intracoronary imaging and physiology, complex percutaneous coronary intervention including chronic total occlusion recanalisation, and acute coronary syndromes. (radcliffecardiology.com)
  • Extending the aspirin-free paradigm to patients with acute coronary syndrome: is it time to change guidelines? (pcronline.com)
  • You may have this procedure to remove plaque from the arteries of your heart ( coronary arteries ). (seekhealthz.com)
  • Treating severely calcified arteries by endovascular means is still a challenge, although atherectomy, stents and lithotripsy are all techniques that are employed. (vascularnews.com)
  • At the University of Miami Health System, experienced vascular surgeons use atherectomy to remove plaque (fatty tissue build-up) from the walls of arteries. (umiamihealth.org)
  • The Institute for Quality and Efficiency in Health Care (IQWiG) investigated the extent to which evidence is available for the benefit and harm of non-invasive computed tomography angiography (CTA) and stress diagnostics using magnetic resonance imaging (MRI) in people with suspected coronary heart disease (CAD) using evidence mapping. (mtrconsult.com)
  • Atherectomy for occlusive disease in the femoral-popliteal and tibial-peroneal segments for claudication in outpatient settings may result in outcomes worse than the natural history. (vascularnews.com)
  • Dr. Mitschke's special clinical interests include pacemaker implantations and treatment of advanced and complex coronary disease, including coronary atherectomy and revascularization of chronic total occlusions. (memorialcardiologyassoc.com)
  • One of the big challenges in treating peripheral vasculature disease is that many of the therapies and devices used today were developed for use in coronary vessels, and peripheral vessels have a different biology and are in a different anatomical location. (ceocfobulletin.com)
  • Lesion preparation using Diamondback 360 orbital atherectomy enhances paclitaxel distribution in. (vascularnews.com)
  • Aims: The aim of this multicentre study was to investigate the in-hospital and midterm outcomes of rotational atherectomy (RA) followed by metallic stent implantation. (elsevier.com)
  • Coronary IVL safely facilitated successful stent implantation and achieved high procedural success in one of the most severely calcified vessel cohorts reported for any PCI trial to date. (shockwavemedical.com)
  • How does laser atherectomy work and what is the learning curve to using it in coronaries? (philipseliiteacademy.com)
  • Is there a learning curve to using laser atherectomy? (philipseliiteacademy.com)
  • Dr. Kevin Croce from Brigham and Women's Hospital in Boston gives a brief explanation of the basic mechanisms of laser atherectomy from his extensive experience as a CHIP interventionalist and user of the technology. (philipseliiteacademy.com)
  • Excimer laser coronary atherectomy (ELCA) is a long-established adjunctive therapy that for some Interventional Cardiologists, is not top of mind. (philipseliiteacademy.com)
  • This app was created in response to the rising interest among interventional cardiologists to learn OCT given its ability to help with image analysis, determination of plaque characteristics, visualization of intra-coronary pathology and stent optimization. (cardiologyapps.com)
  • The OCTAID app is an educational tool which has been developed as a means to teach intra-coronary optical coherence tomography (OCT) with the goal of making it easy to understand for physicians all over the world. (cardiologyapps.com)
  • In October 2020, a completed mini-method assessment for the coronary sinus reducer stent (Neovasc) implantation in refractory angina pectoris treatment was published within the New Methods framework. (mtrconsult.com)
  • The assessed technologies included implantation of a wireless pulmonary artery pressure sensor in patients with advanced heart failure, intrauterine ultrasound-guided transcervical radiofrequency ablation, percutaneous transvascular implantation of a coronary sinus reducing stent, radiofrequency-induced intravesical chemohyperthermia for non-muscle invasive bladder cancer, and Vascular photodynamic therapy with Padeliporfin (Tookad® solution). (mtrconsult.com)
  • TAVRcathAID is an educational tool with step-by-step instructions on how to perform diagnostic coronary angiogram and percutaneous coronary intervention after implantation of a transcatheter aortic valve. (cardiologyapps.com)
  • Atherectomy is a surgical procedure to remove a buildup of fat, cholesterol, and other substances ( plaque ) from the inside of an artery. (seekhealthz.com)
  • You will be sedated for your atherectomy procedure. (umiamihealth.org)
  • The aims of this study were to describe the clinical characteristics, management and in-hospital outcomes of coronary syndrome (ACS) patients with HF in the United Arab Emirates. (biomedcentral.com)
  • Similarly, atherectomy devices which apply mechanical force or laser energy to remove plaque, often inadvertently cut into the vessel wall and cause dissections and perforations. (ceocfobulletin.com)
  • On August 6, 2020, the Ministry of Solidarity and Health published an Order (of August 4, 2020) listing the rotational atherectomy systems ROTAPRO and ROTALINK PLUS of the company Boston Scientific under Title V of the list of reimbursable products and services provided for in Article L. 165-1 of the Social Security Code (LPPR List). (mtrconsult.com)
  • During a coronary angiogram, a type of dye that can be detected on an x-ray is injected into your heart. (heartvascular.net)
  • Renowned coronary physiology researcher, lecturer and iFR pioneer Dr. Justin Davies presents a summary of physiologic assessment and resting pressure indices. (philipseliiteacademy.com)
  • Coronary physiology assessment now has a tremendous level of clinical data to support its use in today's cath lab, but obtaining the most consistent and clinically accurate results is often questioned. (philipseliiteacademy.com)
  • You are invited to a deep-dive live online course on coronary imaging, physiology, and techniques of complex PCI. (wondrmedical.net)
  • How has iFR Co-Registration Changed my Thinking on Coronary Physiology? (wondrmedical.net)
  • A histopathologic analyses of a small number of specimens showed that echo attenuation has been variously related to microcalcification hyalinized fibrous tissue cholesterol crystals or organized thrombus (8 20 27 Kimura S examined 30 atherectomy specimens with attenuated plaques and found advanced atherosclerosis consisting predominantly of cholesterol clefts macrophage infiltration and microcalcification (20). (healthyfutureforkids.com)
  • In November 2016, Cardiovascular Systems, Inc. (CSI) announced that Medikit, Co., Ltd. signed an exclusive distribution agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Japan. (csi360.com)
  • In April 2021, Cardiovascular Systems, Inc. (CSI) announced that RSK Medical Inc. signed an exclusive sales agent agreement to sell its coronary and peripheral Orbital Atherectomy Systems in Canada. (csi360.com)
  • RotaPro™ is the newest atherectomy innovation from Boston Scientific that is easier to use, faster to set up and more intuitive to learn. (coscardio.ie)
  • Huge Coronary Aneurysm in Case of DES as a Very Late Complication! (complex-pci.com)
  • An in-depth introduction to coronary guidewires brings users up to speed with terminology such as tip load and coatings. (cardiologyapps.com)
  • Avinger has announced initiation of INSIGHT, a prospective, global, single arm, multicentre study to evaluate the safety and effectiveness of the Pantheris Lumivascular Atherectomy. (vascularnews.com)
  • Outpatient atherectomy outcomes may be "worse than the natural history of. (vascularnews.com)
  • Explore cases involving dissections, perforations, and atherectomy as well as less common complications such as longitudinal stent deformation, vasospasm, and air embolism. (cardiologyapps.com)

No images available that match "atherectomy coronary"