Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Anti-Asthmatic Agents: Drugs that are used to treat asthma.Asthma, Exercise-Induced: Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).Administration, Inhalation: The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.Peak Expiratory Flow Rate: Measurement of the maximum rate of airflow attained during a FORCED VITAL CAPACITY determination. Common abbreviations are PEFR and PFR.Asthma, Occupational: Asthma attacks caused, triggered, or exacerbated by OCCUPATIONAL EXPOSURE.Forced Expiratory Volume: Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.Bronchodilator Agents: Agents that cause an increase in the expansion of a bronchus or bronchial tubes.Respiratory Sounds: Noises, normal and abnormal, heard on auscultation over any part of the RESPIRATORY TRACT.Allergens: Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Adrenal Cortex HormonesHypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.Hypersensitivity, Immediate: Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.Respiratory Function Tests: Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.Methacholine Chloride: A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.Spirometry: Measurement of volume of air inhaled or exhaled by the lung.Budesonide: A glucocorticoid used in the management of ASTHMA, the treatment of various skin disorders, and allergic RHINITIS.Eosinophils: Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.Beclomethasone: An anti-inflammatory, synthetic glucocorticoid. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of ASTHMA.Bronchi: The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI.Leukotriene Antagonists: A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.Nebulizers and Vaporizers: Devices that cause a liquid or solid to be converted into an aerosol (spray) or a vapor. It is used in drug administration by inhalation, humidification of ambient air, and in certain analytical instruments.Skin Tests: Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Status Asthmaticus: A sudden intense and continuous aggravation of a state of asthma, marked by dyspnea to the point of exhaustion and collapse and not responding to the usual therapeutic efforts.Bronchoconstrictor Agents: Agents causing the narrowing of the lumen of a bronchus or bronchiole.Airway Remodeling: The structural changes in the number, mass, size and/or composition of the airway tissues.Bronchoconstriction: Narrowing of the caliber of the BRONCHI, physiologically or as a result of pharmacological intervention.Bronchitis: Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Adrenergic beta-Agonists: Drugs that selectively bind to and activate beta-adrenergic receptors.Respiratory Hypersensitivity: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL.Ovalbumin: An albumin obtained from the white of eggs. It is a member of the serpin superfamily.Pyroglyphidae: Family of house dust mites, in the superfamily Analgoidea, order Astigmata. They include the genera Dermatophagoides and Euroglyphus.Pulmonary Medicine: A subspecialty of internal medicine concerned with the study of the RESPIRATORY SYSTEM. It is especially concerned with diagnosis and treatment of diseases and defects of the lungs and bronchial tree.Vital Capacity: The volume of air that is exhaled by a maximal expiration following a maximal inspiration.Asthma, Aspirin-Induced: Asthmatic adverse reaction (e.g., BRONCHOCONSTRICTION) to conventional NSAIDS including aspirin use.Sputum: Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Exhalation: The act of BREATHING out.Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.Air Pollution, Indoor: The contamination of indoor air.Occupational Diseases: Diseases caused by factors involved in one's employment.Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.Mites: Any arthropod of the subclass ACARI except the TICKS. They are minute animals related to the spiders, usually having transparent or semitransparent bodies. They may be parasitic on humans and domestic animals, producing various irritations of the skin (MITE INFESTATIONS). Many mite species are important to human and veterinary medicine as both parasite and vector. Mites also infest plants.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Environmental Exposure: The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Air Pollutants: Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or material. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS.Anti-Inflammatory Agents: Substances that reduce or suppress INFLAMMATION.Breath Tests: Any tests done on exhaled air.Nedocromil: A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.Self Care: Performance of activities or tasks traditionally performed by professional health care providers. The concept includes care of oneself or one's family and friends.Airway Resistance: Physiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow.Androstadienes: Derivatives of the steroid androstane having two double bonds at any site in any of the rings.Metered Dose Inhalers: A small aerosol canister used to release a calibrated amount of medication for inhalation.Interleukin-13: A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-LYMPHOCYTES. It appears to play a role in regulating inflammatory and immune responses.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Respiratory System: The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.Cromolyn Sodium: A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.Th2 Cells: Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.Nitrogen Dioxide: Nitrogen oxide (NO2). A highly poisonous gas. Exposure produces inflammation of lungs that may only cause slight pain or pass unnoticed, but resulting edema several days later may cause death. (From Merck, 11th ed) It is a major atmospheric pollutant that is able to absorb UV light that does not reach the earth's surface.Patient Education as Topic: The teaching or training of patients concerning their own health needs.Ethanolamines: AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Tobacco Smoke Pollution: Contamination of the air by tobacco smoke.Emergency Service, Hospital: Hospital department responsible for the administration and provision of immediate medical or surgical care to the emergency patient.Picornaviridae Infections: Virus diseases caused by the PICORNAVIRIDAE.Cockroaches: Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Hospitalization: The confinement of a patient in a hospital.Toluene 2,4-Diisocyanate: Skin irritant and allergen used in the manufacture of polyurethane foams and other elastomers.Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.Puerto Rico: An island in the Greater Antilles in the West Indies. Its capital is San Juan. It is a self-governing commonwealth in union with the United States. It was discovered by Columbus in 1493 but no colonization was attempted until 1508. It belonged to Spain until ceded to the United States in 1898. It became a commonwealth with autonomy in internal affairs in 1952. Columbus named the island San Juan for St. John's Day, the Monday he arrived, and the bay Puerto Rico, rich harbor. The island became Puerto Rico officially in 1932. (From Webster's New Geographical Dictionary, 1988, p987 & Room, Brewer's Dictionary of Names, 1992, p436)Aerosols: Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.Adrenergic beta-2 Receptor Agonists: Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS.Pregnenediones: Unsaturated pregnane derivatives containing two keto groups on side chains or ring structures.Urban Population: The inhabitants of a city or town, including metropolitan areas and suburban areas.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Eosinophil Cationic Protein: One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil cationic protein is a 21-kDa cytotoxic peptide with a pI of 10.9. Although eosinophil cationic protein is considered a member of the RNAse A superfamily of proteins, it has only limited RNAse activity.Occupational Exposure: The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Anti-Allergic Agents: Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)Practice Guidelines as Topic: Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.Interleukin-5: A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.Pulmonary Eosinophilia: A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.Respiratory Mucosa: The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.Air Pollution: The presence of contaminants or pollutant substances in the air (AIR POLLUTANTS) that interfere with human health or welfare, or produce other harmful environmental effects. The substances may include GASES; PARTICULATE MATTER; or volatile ORGANIC CHEMICALS.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Rhinovirus: A genus of PICORNAVIRIDAE inhabiting primarily the respiratory tract of mammalian hosts. It includes over 100 human serotypes associated with the COMMON COLD.Mucus: The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.Housing: Living facilities for humans.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Acute Disease: Disease having a short and relatively severe course.Ozone: The unstable triatomic form of oxygen, O3. It is a powerful oxidant that is produced for various chemical and industrial uses. Its production is also catalyzed in the ATMOSPHERE by ULTRAVIOLET RAY irradiation of oxygen or other ozone precursors such as VOLATILE ORGANIC COMPOUNDS and NITROGEN OXIDES. About 90% of the ozone in the atmosphere exists in the stratosphere (STRATOSPHERIC OZONE).Respiratory Tract DiseasesFenoterol: An adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.Isocyanates: Organic compounds that contain the -NCO radical.Health Surveys: A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Antigens, Dermatophagoides: Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They are proteins, found in mite feces or mite extracts, that can cause ASTHMA and other allergic diseases such as perennial rhinitis (RHINITIS, ALLERGIC, PERENNIAL) and atopic dermatitis (DERMATITIS, ATOPIC). More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the above two species, are among the strongest mite immunogens in humans.Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.Patient Compliance: Voluntary cooperation of the patient in following a prescribed regimen.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.QuinolinesSinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.Parents: Persons functioning as natural, adoptive, or substitute parents. The heading includes the concept of parenthood as well as preparation for becoming a parent.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Bronchoscopy: Endoscopic examination, therapy or surgery of the bronchi.Vehicle Emissions: Gases, fumes, vapors, and odors escaping from the cylinders of a gasoline or diesel internal-combustion engine. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Random House Unabridged Dictionary, 2d ed)Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Urban Health: The status of health in urban populations.Ipratropium: A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Mice, Inbred BALB CLung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.Conjunctivitis, Allergic: Conjunctivitis due to hypersensitivity to various allergens.United StatesPollen: The fertilizing element of plants that contains the male GAMETOPHYTES.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Leukocyte Count: The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.Acetates: Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.Forced Expiratory Flow Rates: The rate of airflow measured during a FORCED VITAL CAPACITY determination.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Disease Management: A broad approach to appropriate coordination of the entire disease treatment process that often involves shifting away from more expensive inpatient and acute care to areas such as preventive medicine, patient counseling and education, and outpatient care. This concept includes implications of appropriate versus inappropriate therapy on the overall cost and clinical outcome of a particular disease. (From Hosp Pharm 1995 Jul;30(7):596)Desensitization, Immunologic: Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Leukotriene E4: A biologically active principle of SRS-A that is formed from LEUKOTRIENE D4 via a peptidase reaction that removes the glycine residue. The biological actions of LTE4 are similar to LTC4 and LTD4. (From Dictionary of Prostaglandins and Related Compounds, 1990)New Zealand: A group of islands in the southwest Pacific. Its capital is Wellington. It was discovered by the Dutch explorer Abel Tasman in 1642 and circumnavigated by Cook in 1769. Colonized in 1840 by the New Zealand Company, it became a British crown colony in 1840 until 1907 when colonial status was terminated. New Zealand is a partly anglicized form of the original Dutch name Nieuw Zeeland, new sea land, possibly with reference to the Dutch province of Zeeland. (From Webster's New Geographical Dictionary, 1988, p842 & Room, Brewer's Dictionary of Names, 1992, p378)MichiganGuideline Adherence: Conformity in fulfilling or following official, recognized, or institutional requirements, guidelines, recommendations, protocols, pathways, or other standards.Absenteeism: Chronic absence from work or other duty.Dyspnea: Difficult or labored breathing.Leukotrienes: A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.Food Hypersensitivity: Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food.Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Goblet Cells: A glandular epithelial cell or a unicellular gland. Goblet cells secrete MUCUS. They are scattered in the epithelial linings of many organs, especially the SMALL INTESTINE and the RESPIRATORY TRACT.Inhalation Spacers: A variety of devices used in conjunction with METERED DOSE INHALERS. Their purpose is to hold the released medication for inhalation and make it easy for the patients to inhale the metered dose of medication into their lungs.Age of Onset: The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.Infant, Newborn: An infant during the first month after birth.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Interleukin-4: A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.Medication Adherence: Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.Chemokine CCL11: A CC-type chemokine that is specific for CCR3 RECEPTORS. It is a potent chemoattractant for EOSINOPHILS.Cost of Illness: The personal cost of acute or chronic disease. The cost to the patient may be an economic, social, or psychological cost or personal loss to self, family, or immediate community. The cost of illness may be reflected in absenteeism, productivity, response to treatment, peace of mind, or QUALITY OF LIFE. It differs from HEALTH CARE COSTS, meaning the societal cost of providing services related to the delivery of health care, rather than personal impact on individuals.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Polymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Pneumonia: Infection of the lung often accompanied by inflammation.Nasal Polyps: Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.Cross-Over Studies: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

Direct costs of occupational asthma due to sensitization in Quebec (1988 to 2002): revisited. (1/37)

BACKGROUND: In a previous study, the authors assessed direct costs for occupational asthma (OA) in a random sample of eight to 10 accepted claims per year for OA between 1988 and 2002. Compensation for loss of income (CLI) was found to be significantly higher for men and for OA caused by low-molecular-weight agents. OBJECTIVES AND METHODS: To identify sociodemographic factors that modulate CLI, the dossier of each claimant in the previous study was re-examined. RESULTS: Higher CLI costs were directly related to the duration of CLI (over which loss of income was reimbursed) (r=0.65). Costs of CLI were higher in patients 30 years of age or older at diagnosis, married subjects and individuals who were offered early retirement or were enrolled in an active interventional rehabilitation program. Higher CLI costs in men, but not in women, were associated with the following sociodemographic factors: older age, different rehabilitation program (early retirement and active program versus no specific program) and married status. Older age was found to be significant in the multivariate analysis performed for men. The cost of CLI was higher in workers with OA caused by low-molecular-weight agents. Although proportionally fewer men and younger workers were affected with OA caused by low-molecular-weight agents, the longer duration of CLI for this category of agent could explain the higher costs. CONCLUSION: Higher costs for CLI were associated in men (but not women) with older age, married status and type of rehabilitation program (early retirement and active rehabilitation). Higher costs of CLI for OA caused by low-molecular-weight agents were associated with a longer duration of CLI per se, and not with sociodemographic factors.  (+info)

Barriers to the recognition and reporting of occupational asthma by Canadian pulmonologists. (2/37)

BACKGROUND: Occupational asthma is a common, but probably under-recognized problem. OBJECTIVE: To identify the factors that suggest work-related asthma when a pulmonologist encounters an adult patient with new-onset asthma, and to identify the barriers to recognizing and reporting such cases. METHODS: A postal questionnaire was sent to all pulmonologists in Canada. The questionnaire asked participants to respond to several questions about recognizing, diagnosing and reporting occupational asthma. Answers were scored using visual analogue scales. RESULTS: A total of 201 eligible responses were received from 458 pulmonologists. Pulmonologists identified that the most important factor in initially considering the role of work in occupational asthma was having seen others affected at the same workplace, or exposed to the same agent. Important perceived barriers to considering a diagnosis of occupational asthma were physicians' low awareness, lack of knowledge and time. The most important barriers to reporting cases were the pulmonologists' perceived patient concerns regarding job security and income. Quebec pulmonologists generally perceived barriers to recognizing and reporting occupational asthma to be less important, and believed that the use of specific inhalation challenge was more important in considering a diagnosis. CONCLUSIONS: Pulmonologists most readily recognized occupational asthma caused by a substance or process that they previously encountered as a possible cause of asthma. Time constraints and knowledge may hamper their ability to recognize occupational asthma. Concerns regarding the effect of the diagnosis on the patient's job and income may discourage reporting.  (+info)

Work-related respiratory symptoms and lung function among solderers in the electronics industry: a meta-analysis. (3/37)

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Environmental isocyanate-induced asthma: morphologic and pathogenetic aspects of an increasing occupational disease. (4/37)

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Sensitization and irritant-induced occupational asthma with latency are clinically indistinguishable. (5/37)

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Guidelines for the management of work-related asthma. (6/37)

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Assessment of public health impact of work-related asthma. (7/37)

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Is specific IgE antibody analysis feasible for the diagnosis of methylenediphenyl diisocyanate-induced occupational asthma? (8/37)

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Surveillance data from four states on work-related asthma are now available online from the Work-Related Lung Disease Surveillance System (eWoRLD), developed and maintained by CDCs National Institute for Occupational Safety and Health. Work-related asthma data presented through this surveillance system include information on associated industry, occupation, and exposures. Tables using data from California, Massachusetts, Michigan, and New Jersey for the period 1993-2006 now are available online from eWoRLD at http://www2a.cdc.gov/drds/worldreportdata/subsectiondetails.asp?archiveid=1&subsectiontitleid=23. More years of state-based work-related asthma data will be posted online as they become available. Additional information about the state-based work-related asthma program is available at http://www.cdc.gov/niosh/topics/surveillance/ords/statebasedsurveillance.html. ...
Background: The links between asthma and rhinitis are nowadays referred to as the united airways disease (UAD). Current evidence shows that the UAD model seems to be applicable to occupational rhinitis (OR) and occupational asthma (OA). Objective: We aimed to objectively assess, in the context of specific inhalation challenge (SIC) testing, the concomitance of bronchial and nasal reaction in the investigation of OR and OA Methods: Forty-three subjects with a history of work-related asthma symptoms underwent SIC for confirmation of OA and investigation of OR. Subjects underwent assessment of changes in bronchial calibre by spirometry and assessment of nasal patency and airway inflammation by acoustic rhinometry and nasal lavage. Results: A positive nasal challenge was observed in 25 SIC whereas a positive bronchial challenge was observed in 17 SIC. A concomitant positive nasal and bronchial challenge was observed in 13 instances. This association was significant (risk ratio= 1.7; 95% CI=1.0 to ...
Work-related asthma (WRA) includes work-exacerbated asthma (preexisting or concurrent asthma worsened by factors related to the workplace environment) and occupational asthma (new onset asthma attributed to the workplace environment) (1,2). WRA is a preventable occupational lung disease associated with serious adverse health and socioeconomic outcomes (1,2). Among workers with similar occupational
Sensitizer-induced occupational asthma immunologic form of asthma which occurs due to inhalation of specific substances (i.e., high-molecular-weight proteins from plants and animal origins, or low-molecular-weight agents that include chemicals, metals and wood dusts) and occurs after a latency period of several weeks to years.[1]. Irritant-induced (occupational) asthma is a non-immunologic form of asthma that results from a single or multiple high dose exposure to irritant products. It is usually develops early after exposure; however can also develop insidiously over a few months after a massive exposure to a complex mixture of alkaline dust and combustion products, as shown in the World Trade Center disaster. Unlike those with sensitizer-induced occupational asthma, subjects with irritant-induced occupational asthma do not develop work-related asthma symptoms after re-exposure to low concentrations of the irritant that initiated the symptoms.[2] Reactive airways dysfunction syndrome (RADS) is ...
According to the California Work-Related Asthma Prevention Program, part of the Occupational Health Branch of California Department of Public Health, cleaning products used in workplaces can cause or trigger work-related asthma. To prevent harsh affects of cleaning products, employers should make sure the safest products and practices are used in the workplace. The program has found that nearly 10 percent of all work-related asthma cases were caused by exposure to cleaning products. Most of these cases had new asthma that started only after they began work - the exposures caused their asthma. About one in five people (almost 20 percent) used cleaning products directly, such as janitors. The other 80 percent of workers attributed their asthma symptoms to cleaning products used nearby. Many workplaces, like schools, hospitals, and restaurants are places where everyone, including children, can be affected by cleaning products. How can asthma from cleaning products be prevented? ...
Abstract/Full Text -- Ding. Pneumococcal Vaccine for Only Half With Work-Related Asthma. WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Adults with work-related asthma are more likely that those with non-work-related asthma to have received pneumococcal vaccination, although only 53.7 percent with work-related asthma have been vaccinated, according to a study published online Sept. 27 in the American Journal of Preventive Medicine.. Abstract/Full Text. Working With a Scribe Improves Physician Satisfaction. WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Working with a scribe significantly improves physicians overall satisfaction, satisfaction with chart quality and accuracy, and charting efficiency, according to a study published online Sept. 11 in the Annals of Family Medicine.. Abstract/Full Text. Chronic Respiratory Disease Mortality Up From 1980 to 2014. TUESDAY, Sept. 26, 2017 (HealthDay News) -- From 1980 to 2014 there was a considerable increase in mortality from chronic respiratory ...
Walsh SL, Wells AU, Desai SR, Poletti V, Piciucchi S, Dubini A, Nunes H, Valeyre D, Brillet PY, Kambouchner M, Morais A, Pereira JM, Moura CS, Grutters JC, van den Heuvel DA, van Es HW, van Oosterhout MF, Seldenrijk CA, Bendstrup E, Rasmussen F, Madsen LB, Gooptu B, Pomplun S, Taniguchi H, Fukuoka J, Johkoh T, Nicholson AG, Sayer C, Edmunds L, Jacob J, Kokosi MA, Myers JL, Flaherty KR, Hansell DM, Multicentre evaluation of multidisciplinary team meeting agreement on diagnosis in diffuse parenchymal lung disease: a case-cohort study., Lancet respiratory, 2016;:557-565,10.1016/S2213-2600(16)30033-9 ...
Background Periodic health surveillance (HS) of workers can identify early cases of occupational asthma. Information about its uptake and its content in the UK is lacking. Aims To identify the overall levels of uptake and quality of HS for occupational asthma within three high risk industry sectors in the UK. Methods A telephone survey of employers, and their occupational health (OH) professionals, carried out in three sectors with exposures potentially capable of causing occupational asthma (bakeries, wood working and motor vehicle repair). Results A total of 457 organizations participated (31% response rate). About 77% employed ,10 people, 17% between 10 and 50 and 6% ,50. Risk assessments were common (67%) and 14% carried out some form of HS for occupational asthma, rising to 19% if only organizations reporting asthma hazards and risks were considered. HS was carried out both by in-house (31%) and external providers (69%). Organizational policies were often used to define HS approaches (80%), ...
Symptoms of Occupational asthma - Bakers including 4 medical symptoms and signs of Occupational asthma - Bakers, alternative diagnoses, misdiagnosis, and correct diagnosis for Occupational asthma - Bakers signs or Occupational asthma - Bakers symptoms.
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GPs need to be better at recognising occupational asthma after figures show many people who develop work-related asthma are not correctly diagnosed.
Vandenplas O, Suojalehto H, Aasen T, Baur X, Burge PS, de Blay F, Fishwick D, Hoyle J, Maestrelli P, Muñoz X, Moscato G, Sastre J, Sigsgaard T, Suuronen K, Walusiak-Skorupa J, Cullinan P, the ERS Task Force on Specific Inhalation Challenges with Occupational Agents, Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement, Eur Respir J, 2014;43:1573-1587 ...
Occupational asthma (OA) is steadily emerging as the principal cause of respiratory disease due to the workplace environment. One of the key means to ascertain diagnosis of OA is specific inhalation challenge (SIC) with occupational agents. This review: 1) describes the methodology of SIC, with a special emphasis on procedures aimed at increasing the safety and validity of these tests; and 2) outlines the roles of SIC in the diagnosis of OA in clinical and medicolegal assessment, epidemiological studies, surveillance programmes and the investigation of the pathophysiological mechanisms of asthma and OA. We discuss areas of future development, including the development of apparatus which allows exposure of subjects to low and stable concentrations of the occupational agent and the assessment of preventive procedures.. ...
Work-related asthma includes work aggravation of preexisting asthma and new-onset asthma induced by occupational exposure.. To identify cases of asthma related to the occupational exposure, assess the severity and control of asthma at work and appreciate the consequences on employment, we conducted a cross-sectional study involving all active asthmatic patients who had consulted the pulmonology department of the University Hospital of Sfax in Tunisia for a period of four months.. We collected the records of 104 patients. The group of elementary occupations was 69.2%. Workers in the textile and food industry represented 16.3% and 15.4% respectively. Symptoms appear in the first ten years of occupational exposure in 39.4% of cases. The asthma was 31.7% partially controlled and uncontrolled in 7.7% of cases. The professional investigation had concluded that the occupational origin of asthma represented 44.2% of patients and the worsening by the professional environment 28.8% of cases. The ...
Another name for Occupational Asthma is Asthma. A nebulizer is a small plastic bowl with a lid and a mouthpiece. The bowl is connected to a tube that ...
Occupational Asthma - Boiler Cleaners information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.
... is a lung disorder in which substances found in the workplace cause the airways of the lungs to swell and narrow. This leads to attacks of wheezing, shortness of breath, chest tightness, and coughing.
If you have suffered an industrial injury such as occupational asthma - we can help.. Here is a guide to the standard compensation amounts: ...
I agree with both Trisha and Alex, and that is not to undermine Barbaras condition or concerns. Im sure there are people that are adversly affected by many aspects of their jobs. Some are truly legitimate and SHOULD be addressed by the employer. however I think there may be some individuals who would jump on the band wagon and persue it for all its worth--(is this a can of worms?) hope no one is offended, just MY opinion. jerry P. Emry wrote: , Dear ? , , I would like more information on the condition you discribe. I would also , like to know who you are and who you are doing the research for. , , I think that such information could be a dangerous thing in some hands. I , dont have a back-up profession and a note in my employment folder could , block future employment if/when we run out of grant money here, or when , the boss retires. , , I would like to know if others feel this way about medical information and , the workplace. , , Trisha , Seattle , , On Fri, 16 Oct 1998 [email protected] ...
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equivalent of 134 people every week - according to new figures from the TUC. The statistics, published in the union bodys Risk online bulletin, come ...
Mounting evidence suggests that diisocyanates are able to bind airway epithelial cell proteins, resulting in airway inflammation with cytokine and chemokine production and cellular recruitment [29]. The toxicity of diisocyanates toward airway epithelial tissues has also been reported, and MDI and HDI prepolymers were shown to induce airway epithelial barrier dysfunction that was partly associated with altered glutamine levels [30, 31]. The effect of TDI on the expression of lung cytokine P450 enzymes has also been documented [32]. We attempted to culture human bronchial epithelial cells, Beas-2B, with TDI-HSA conjugates to identify the source of the IL-8 detected in the sputum of TDI-induced asthma patients [33]. The production of IL-8 and regulated upon activation in normal T cell expressed, and secreted (RANTES) was significantly increased in a dose-dependent manner after exposure to a peripheral mononuclear cell culture supernatant derived from a TDI-induced asthma patient, and this effect ...
Immediate hypersensitivity reactions ranging from mild urticaria to life threatening anaphylaxis after exposure to natural rubber latex have been reported frequently in health care workers while occupational asthma due to latex exposure is less well studied. The results of specific challenge tests and immunological tests in four health care workers with work related respiratory and skin disorders induced by the use of latex gloves are described. Occupational asthma was confirmed in three subjects by specific challenge tests. All had a positive skin test reaction to the latex extract; specific IgE antibodies were detected in only one subject. The fourth subject had a negative specific inhalation and skin test reaction to the latex extract. Peak expiratory flow monitoring at work and away from work showed a pattern consistent with work related asthma. These findings confirm that latex is a cause of occupational asthma in health care workers.. ...
The article discusses occupational asthma as the most common occupational lung disease in western countries. The disease is found to a contribution on the exposure to silica, asbestos, and coal dust. Its association on the kind of occupation that a person has, makes the diagnosis of the disease to be unsuccessful. In order for the diagnosis to be successful, clinicians have to get involved with the primary, secondary and tertiary prevention of occupational asthma ...
About the Author Home Remedies For Asthma - Easy And Simple 0 Any person who believes he secretions can not drain and strengthens his injury to full relocation. My mom says Im obese because my asthma medicine cells, chick embryo, and ingredients similar to antifreeze, among other things. Asthma symptoms can be brought on by dozens of different things, and into the esophagus and back down into the lungs causing irritation. Ive read that the more asthma attacks you , has also proven successful in preventing asthmatic attacks in some persons.. People with breathing problems that can breath steamy air often report up within the middle of the night with terribly strong n sharp. Van Helmont, the famous physician who suffered from asthma was the is you can apply for asthma grants especially if you are suffering from chronic asthma problem. With good performance patients on doctors advice can reduce is significantly abnormal chart and i definately have asthma. These exercises are not only a ...
BACKGROUND:. Respiratory diseases are strongly related with exposure in the workplace. A considerable proportion of adult onset asthma is associated with these exposures. The importance of occupational risk factors for asthma has been underestimated, particularly among women. The occupational asthma study (ECRHS-OA) forms part of a wider international multicentre survey on respiratory health (European Community Respiratory Health Survey-ECRHS). The first phase of the ECRHS was conducted in 1991/92 and examined risk factors for asthma and atopy in subjects aged 20-44 years. The study updated (ECRHS-II), following-up approximately 17,000 young adults from 12 countries (Australia, Belgium, France, Germany, Iceland, Italy, Norway, Spain, Sweden, Switzerland, UK and USA).. The study provided valid and precise estimates on the importance of specific occupations, industries and exposures in relation to asthma incidence and prevalence, similar estimates for other respiratory symptoms and diseases and ...
To investigate the incidence of occupational asthma and its relationship to new cases of persistent asthma, the data was collected from two national registers which cover practically all new cases of both diseases. In 1986 to 1993, the annual incidence of persistent asthma in adults from 15 to 64 years increased from 6,645 to 8,056 21%. The...
How to deal with an asthma attack at work - description and flow diagram Occupational asthma guidance - G?? (HSE guidance) Occupational asthma standard of care - PDF (link) CWH respiratory questionnaire?? Case study - video of Jane (beauty) ...
Learn about the causes, symptoms, diagnosis & treatment of Environmental Lung Diseases from the Home Version of the Merck Manuals.
Full text for this publication is not currently held within this repository. Alternative links are provided below where available. ...
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With the reduction in the disease burden from the pneumoconioses in recent years, especially in developed countries, occupational asthma has emerged as the occupational lung disease of greatest importance. It is usually the most common respiratory condition reported in occupational disease surveillance programmes and makes a substantial contribution to the burden of asthma in the community, with an estimated population attributable risk of 15% and estimated annual cost to the USA of $US1.6 billion.1 Therefore, the introduction of prevention strategies to reduce the impact of occupational asthma, should be strongly supported.. The editorial by Snashall in this issue2 describes the latest proposal by the Health and Safety Commission (HSC) to reduce the incidence of occupational asthma in the United Kingdom.3 This article acknowledges the limited success of past HSC prevention programmes. The proposed Strategy has five components corresponding to the key programmes in Securing health together, the ...
Occupational asthma is an occupational lung disease and a type of asthma. Like other types of asthma, it is characterized by airway inflammation, reversible airways obstruction, and bronchospasm, but it is caused by something in the workplace environment. Symptoms include shortness of breath, tightness of the chest, nasal irritation, coughing and wheezing. The first person to use it in reference to a medical condition was Hippocrates, and he believed that tailors, anglers and metalworkers were more likely to be affected by the disease. Although much research has been done since, the inflammatory component of asthma was recognized only in the 1960s. Hypersensitivity pneumonitis is a related condition, with many occupational examples (e.g. flock workers lung, farmers lung, and indium lung). However, although overlapping in many cases, hypersensitivity pneumonitis may be distinguished from occupational asthma in that it isnt restricted to only occupational exposure, and involves type III ...
Sensitization: plastics (TDI and MDI), car paints (HDI and IPDI), polyurethanes (TDI), casting/melts and glues (MDI). Exposure; purely via the airways, may induce cutaneous sensitisation even in the absence of any contact with the skin. Isocyanate induced asthma (particularly TDI) is characterized by lymphocyte activation and secretion of pro-inflammatory cytokines. After exposure has ceased, a "remodelling" of the airways persists. The realisation of the problems associated with TDI, MDI and HDI, etc has led the industries to use oligomers with high molecular weights (BIC) with the aims of reducing the risks of sensitization. The norms for tolerable levels of these monomers are not sufficient to prevent work-related asthma. No norms have been fixed for polyisocyanates or polymer precursors. The response to TDI is regulated by the MHC class II loci DQA1 and DQB1. Fire retardants contain polyurethanes. A Swedish study performed in 2001 demonstrated that above 300°C these polyurethanes degrade ...
Sensitization: plastics (TDI and MDI), car paints (HDI and IPDI), polyurethanes (TDI), casting/melts and glues (MDI). Exposure; purely via the airways, may induce cutaneous sensitisation even in the absence of any contact with the skin. Isocyanate induced asthma (particularly TDI) is characterized by lymphocyte activation and secretion of pro-inflammatory cytokines. After exposure has ceased, a "remodelling" of the airways persists. The realisation of the problems associated with TDI, MDI and HDI, etc has led the industries to use oligomers with high molecular weights (BIC) with the aims of reducing the risks of sensitization. The norms for tolerable levels of these monomers are not sufficient to prevent work-related asthma. No norms have been fixed for polyisocyanates or polymer precursors. The response to TDI is regulated by the MHC class II loci DQA1 and DQB1. Fire retardants contain polyurethanes. A Swedish study performed in 2001 demonstrated that above 300°C these polyurethanes degrade ...
Minister for Health. 10 April 2013. Minister for Health Tanya Plibersek today announced $7.9 million for 11 Partnerships for Better Health - Partnership Projects including research into medication regimes for kidney transplants, chlamydia testing, work-related asthma and cancer, suicide prevention, and mental health disorders in rural children.. Ms Plibersek made the announcement today at the University of Adelaide where she met with grant recipient Professor John Lynch who will receive $273,131 for a whole-of-population study into child health and development.. This study is supported by the Australian Government and project partners from the Womens and Childrens Health Network and the South Australian Department for Education and Child Development.. "The Australian Government is focussed on improved patient care, better disease prevention and more cost-effective delivery of services," Ms Plibersek said.. Jointly funded through the National Health and Medical Research Council and partners, ...
... in indoor swimming-pool air K.M. Thickett1, J.S. McCoach1, J.M. Gerber4, S. Sadhra3 and P.S. Burge1 1 Dept of Respiratory Medicine, Occupational Lung Diseases Unit, Heartlands Hospital, Birmingham, UK. 4 Institut National de Recherche et de Securite, Vandoeuvre les Nancy Cedex, France. 3 Institute of Occupational Health, University of Birmingham, Birmingham,…
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The present case of fatal asthma attack was due to acute exacerbation of work-related asthma that developed in a plastic injection process worker with a history of asthma in remission. The deceased patient led a normal life without manifestations of asthma symptoms or any treatments. However, he began to exhibit typical late-stage asthma symptoms 4 years after working with injection process simulation. Unaware of the occupational cause of those symptoms, he continued to work and finally succumbed to an asthma attack.. Occupational asthma is classified as sensitizer- or irritant-induced asthma depending on the presence or absence of sensitization and a latency period. Sensitizer-induced asthma occurs as a result of immunologic sensitization and is preceded by a latency period after exposure to asthma-triggering substances in the workplace [8]. The latency period between exposure to the causative substances and manifestations of symptoms may range from several weeks to years depending on the phase ...
... includes a wide range of conditions, of which some develop shortly after exposure, such as work-related asthma and legionella infections.
Occupational asthma from nickel sensitivity was confirmed in a male worker (SB) by allergy skin tests and inhalational challenge. In an ammonium sulphate coprecipitation test 63Ni was selectively precipitated from SB plasma indicating antibody with nickel related specificity. Preincubation of 63Ni with human serum albumin (HSA) increased the specificity of the coprecipitation test. Blocking experiments with nickel and copper(II) salts effectively inhibited the binding of 63Ni to antibody of SB plasma but did not affect control tests or that for antibodies to an unrelated antigen, ampicillin. Co2+ slightly inhibited the binding of 63Ni, while Zn2+ and Mn2+ failed to inhibit. This deactivation pattern corresponds to the known sequence of binding of these metals to the primary copper binding site of HSA. It is concluded that the antigenic determinant depends on the combination of Ni2+ with HSA at this specific copper/nickel plasma transport site.. ...
The INTEROCC project is a large-scale multinational brain tumour case-control study, conducted in seven countries (Table 2) included in INTERPHONE. The objective of INTEROCC is to address outstanding questions concerning occupational agents in the disease. Estimates of chemical and ELF exposures were determined for INTEROCC participants, and a number of manuscripts are currently submitted or in preparation that focus on risk of brain tumours in relation to such exposures. However, while the occupational part of the INTERPHONE questionnaire included source based questions to identify subjects with likely substantial exposures to EMF, this work has not yet been exploited and exposure assessment in INTEROCC to date has been based solely on job titles (i.e. linking job titles to estimates of chemical and ELF exposure based on updates of existing JEMs), with the possibility of exposure misclassification since subjects with the same job title may actually have vastly different exposure ...
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Asthma is a serious chronic disease of the lungs that is caused by swelling in the airways. There is no cure for asthma but it can be prevented and controlled with proper care
MicroRNAs are small non-coding RNAs that regulate gene expression at the post-transcriptional level. While they have been implicated in various diseases, the profile changes in allergen inhalation challenge are not clarified in human. We aimed to evaluate changes in the microRNA profiles in the peripheral blood of asthmatic subjects undergoing allergen inhalation challenge. Seven mild asthmatic subjects participated in the allergen inhalation challenge. In addition, four healthy control subjects (HCs) were recruited. MicroRNA profiles in peripheral blood samples (pre-challenge and 2 hours post-challenge) were measured by the NanoString nCounter assay to determine changes in miRNA levels as these asthmatic subjects underwent an allergen inhalation challenge. One common miRNA, miR-192, was significantly expressed in both comparisons; HCs vs. pre-challenge and pre- vs. post-challenge, showing that miR-192 was significantly under-expressed in asthmatics compared to HCs and decreased in post-challenge at an
stress, depression) Case reports and a case control study of work- related irritative VCD have reported that VCD and work-related asthma, particularly Reactive Chemical irritants Airways Dysfunction Syndrome (RADS) may Olfactory stimuli have similar presentations3-5. For example, a 44 year old railroad worker was Rhinitis/postnasal drip exposed to anhydrous ammonia after a rail car leaked3. He immediately developed a cough, hoarseness, Supraglottic disorders Laryngomalacia burning eyes, tearing, rhinitis and felt "his lungs and Exercise-induced supraglottic closure stomach to be on fire". He was treated with inhaled Laryngospasm Intubation bronchodilators and corticosteroids. His hoarseness Airway manipulation persisted. Five months later he was found to have an abnormal inspiratory loop on spirometry, a negative methacholine challenge test and paradoxical adduction Nocturnal aspiration of his vocal cord on laryngoscopy. A second example, Vocal cord paresis Prolonged intubation with a less ...
While occupational asthma is the most important respiratory occupational disease in industrialized societies, the official data in our country still show dust diseases such as silicosis as the most common occupational lung diseases.
cough asthma virus treating asthma severe asthma cough asthma asthma inhalers generic steroid cough asthma information on asthma asthma problems winter occupational asthma and its management cough asthma A persistent chronic night time cough is one of the most common symptoms of mild asthma. A cough is a natural reflex...
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The medicines may have adverse effects to your mouth, teeth, asthma, such as steroid-resistant asthma, occupational asthma, nocturnal asthma, exercise-induced asthma, intrinsic asthma, and allergic asthma. Related Articles Home Remedies For Asthma Cough That Works Besides, it is a good idea to stay away from dairy lifelong illness and gave much fame and acclaim to the physician. Why the increase in allergies, especially life-threatening Asthma, but I dont resembling the idea of there man any amount of meds in my milk. http://elijahcoopertv.hawapets.org/2016/07/28/poor-hygiene-or-increased-stress-levels-are-not-as-is-popularly-believed-the-cause-of-acne-though-they-may-aggravate-the-problemSwollen salivary glands can cause dry throat, one of the frequent conditions become tight and the lining of the air passages swell. Kaufman states that "fungus has the ability to colonize from time to time and from patient to patient. One of the most effective ways to reduce asthma attacks and by age one, the ...
A-amylase is a starch-cleaving enzyme which is used as a flour additive in the baking industry. It is product of Aspergillus oryzae. Flour for bread making must also contain an optimum level of a-amylases. a-amylases are enzymes responsible for the conversion of starch to maltose which is further broken down to form glucose - the sugar required for effective fermentaion of the yeast. If the concentration of a-amylases is too low, too little maltose will be formed and the bread will not rise sufficiently. Too much a-amylase and bread can end up as ‘sticky’ as a result of substances called dextrins forming [1].. Inhalation of dust from different enzymes can be the cause of occupational asthma in exposed workers. Enzymes from different sources are being increasingly used in food. Few cases of food allergy to alpha-amylase induced by eating bread have been reported. Those cases were reported in bakery-related patients and in a pharmaceutical-industry worker [2].. Several studies have ...
This bow is made from spruce wood, sinew, and shell or horn. Made from one piece of spruce, broad, flat and tapered at ends forming rounded knobs. Its backside is flat with belly side keeled from end to end with a furrowed center on about 3/4 of its length. Supports or backing of braided sinew are wrapped spirally by another strand of sinew to hold it together. Twenty-four sinew strands are wrapped around the central sinew cord and bow together using under hitches to tie Southern style. Dimensions: 52.5 in. long x 2 in. wide at widest part x.75 in. thick.¬ulture: Alutiiq-Sugpiaq ...
This bow is made from spruce wood, sinew, and shell or horn. Made from one piece of spruce, broad, flat and tapered at ends forming rounded knobs. Its backside is flat with belly side keeled from end to end with a furrowed center on about 3/4 of its length. Supports or backing of braided sinew are wrapped spirally by another strand of sinew to hold it together. Twenty-four sinew strands are wrapped around the central sinew cord and bow together using under hitches to tie Southern style. Dimensions: 52.5 in. long x 2 in. wide at widest part x.75 in. thick.¬ulture: Alutiiq - Sugpiaq ...
This statement was written by a group of pulmonologists and pediatric pulmonologists belonging to the corresponding professional associations ÖGP …
Aims : Access educational materials here To provide a detailed review of the various patterns that are seen on high-resolution CT chest imaging; to review the sizing, appearance, and distribution of lung opacities in relation to the various differential diagnoses in the clinical setting; to provide guidelines for basic differential diagnosis on the basis of clinical history, the distribution of various patterns, and the presence of associated abnormalities ...
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Objectives-To examine the effect of occupation on respiratory symptoms in a randomly selected adult population aged 20-44 years. Methods-It is based on the phase II sampling of the New Zealand part of the European Community respiratory health survey. 1609 people 63.9% response rate completed a detailed respiratory questionnaire. Of those...
The three main components of wood, namely, cellulose, hemicellulose, and lignin, can be used in various areas. However, since lignin covalently crosslinks with wood polysaccharides creating networks that is an obstacle for extraction, direct extraction of different wood components in high yield is not an easy matter. One potential approach to overcome such obstacles is to treat the wood with specific enzymes that degrade the networks by specific catalysis. However, the structure of wood is so compact that the penetration of the wood fibers by large enzyme molecules is hindered. Thus, the pretreatment of wood prior to the application of enzymes is necessary, for "opening" the structure.. One pretreatment method that was performed in this thesis is based on kraft pulping, which is a well-established and industrialized technique. For untreated wood, the wood fibers cannot be attacked by the enzymes. A relatively mild pretreatment was sufficient for wood polysaccharides hydrolyzed by a culture ...
Health, ...Allergists pulmonologists and general practitioners can learn the app... For three decades this conference has assisted medical professionals ...The four-day conference features lectures and case-based workshops wit...All participants will observe presentations and participate in case-st...,34th,Annual,Pulmonary,and,Allergy,Update,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Atopy is a frequent host characteristic that is a pre-requisite for susceptibility to asthma. Sensitization and exposure to allergens as a cause of asthma is well supported by epidemiological studies, in particular those addressing occupational asthma. The immunobiology of allergic inflammation has been explored using murine models that have provided valuable insights into the basis for the inflammatory process. The identification of two CD4 T cell subsets producing different profiles of cytokines advanced the field of T cell biology. CD4 cells (Th2) producing preferentially interleukin (IL)-4 and IL-5 are important for immunoglobulin synthesis and eosinophil differentiation, survival and activation, respectively. IL-13 has additional properties such as promoting mucous cell differentiation, fibroblast and smooth muscle activation.6 Allergic inflammation is triggered in an environment which promotes CD4 Th2 differentiation, based on the influence of such factors as IL-4 itself, thymic stromal ...
A Comparison between Venables Standardized Respiratory Questionnaire and Pre-Shift Spirometry in Screening of Occupational Asthma in a Steel Industry
It is axiomatic that the diagnosis of RMSF must be based onthe clinical features and an appropriate epidemiologic setting rather than on any sin-gle laboratory test. The small casters are de- medium caster size (B) are the most func-signed to rest the chair and to be in minimal contact with ground during tional for individuals with CP. The other complication is leaving an imbalance with an excessivelystrong flexor digitorum profundus and extensor digitorum longus causingthe swan neck deformity to develop. Thesecond approach is to wait until the deformity is so severe that children arehaving symptoms from the deformity, usually at 10 to 14 years of age, then11. Governments, notunexpectedly, focus on the efficient transport of goods fromagricultural and manufacturing areas and modern safety features areoften omittedThe heterogeneous traffic stream seen in the developing worldresults in the troubling problem of vehicle mismatch. If a diagnosis of occupational asthma is made, the patient should ...
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Learn more about asthma basics including what asthma is, the causes of asthma and common signs and symptoms of asthma with expert advice on the topic.
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Ryo, U.Y.; Kang, B.; Townley, R.G., 1976: Cromolyn therapy in patients with bronchial asthma. Effect on inhalation challenge with allergen, histamine, and methacholine
1. Inhalation (breathing): Formaldehyde is highly irritating to the upper airways. The concentration of formaldehyde that is immediately dangerous to life and health is 100 ppm. Concentrations above 50 ppm can cause severe pulmonary reactions within minutes. These include pulmonary edema, pneumonia, and bronchial irritation which can result in death. Concentrations above 5 ppm readily cause lower airway irritation characterized by cough, chest tightness and wheezing. There is some controversy regarding whether formaldehyde gas is a pulmonary sensitizer which can cause occupational asthma in a previously normal individual. Formaldehyde can produce symptoms of bronchial asthma in humans. The mechanism may be either sensitization of the individual by exposure to formaldehyde or direct irritation by formaldehyde in persons with pre-existing asthma. Upper airway irritation is the most common respiratory effect reported by workers and can occur over a wide range of concentrations, most frequently ...
Irritants and sensitizers that can induce an allergic response following contact with the skin. Quats are also known to cause occupational asthma in cleaning workers and preliminary evidence indicates they may cause adverse genetic and reproductive effects. Chemicals in this class are persistent in the environment and toxic to aquatic organisms. Like triclosan, quats are anti-microbial agents and there is concern that their widespread use in household disinfectants and cosmetics is contributing to antibiotic resistant bacteria, thus limiting treatment options for microbial infections. The Canadian Medical Association has called for a ban on antibacterial consumer products ...
We are reviewing the Workplace exposure standards for airborne contaminants to ensure they are based on the highest quality, contemporary evidence and supported by a rigorous, scientific approach.. The draft evaluation reports for each chemical will be available for public comment. Chemicals will be released alphabetically throughout 2019 and 2020. Public comment will be open for each release for a period of four weeks on Engage.. The chemical release groups and the anticipated dates for opening public comment are outlined below. Please note these dates are indicative only. For the latest information please continue to visit Engage.. ...
An occupational disease or illness refers to any disease that arises from exposure to a risk factor while at work or during a work-related activity.
Pulmonology Advisor offers the latest asthma, COPD, lung cancer, pneumonia news articles for pulmonologists and the healthcare community. Download the FREE app now.
Asthma: Asthma in Canada. Over 2 million Canadians have asthma, and despite the availability of effective treatment, approximately 9 in 10 people with asthma do not have it under control.
World Asthma Day is an annual event to improve asthma awareness and care around the world, falling on May 6, 2014. You can prepare for an asthma emergency.
View list of generic and brand names of drugs used for treatment of Asthma. You can find more information including dosage, side effects of the Asthma medicine.
... makes it hard to breathe. But with treatment, the condition can be managed so that kids can still do the things they love. Learn all about asthma.
... makes it hard to breathe. But with treatment, the condition can be managed so that kids can still do the things they love. Learn all about asthma.
Although Asthma is a single chronic disease, depending on the triggers and symptoms, they are commonly classified into different types.
Whether you pack a suitcase every week or once a year, you probably know that traveling takes a little extra preparation when you have asthma.
An improved understanding of indoor air chemistry would significantly benefit human health. It is estimated that at least 15% of new-onset asthma cases can be attributed to workplace exposures. The 2011 American Thoracic Society report on work exacerbated asthma identified 1) better exposure assessment methods to identify and characterize the complex exposures in workplaces and 2) investigating pathophysiological mechanisms such as neurogenic inflammation and epithelial response to oxidant stress as two of the major research gaps for addressing work exacerbated asthma reduction. Unfortunately even though indoor air is identified as a significant link between occupational lung disease and its prevention/reduction, it has been poorly understood or characterized. Research in gas-phase and surface-phase chemistries, improved field and analytical sampling methods and mechanism-based toxicology may all be used to improve indoor air quality ...
The aim of this study was to evaluate the cumulative effect of traffic related pollutants on subjects which mainly included traffic police. This evaluation is important to cater to the statistic that occupational asthma is the most common form of lung disease in the world which places the population with high exposure at great risk. We qualify the effect of exposure to pollutants like carbon monoxide, particulate diesel and other gaseous pollutant which can cause interminable harm that demonstrate as migraine, hazy vision, trouble in focus and confusion. They may also be carcinogenic with higher rates of malignancy. The predominance of respiratory complications among the policemen in highly polluted areas is higher than their counterparts. A careful assessment of history and quantification of severity markers and peak expiratory flow rate helps us identify patients who may require intensive immediate care or even hospitalization. The main objective of this work is to analyze the present health ...
Stage models are becoming increasingly popular in explaining change from current behavior to more environmentally friendly alternatives. We review empirical applications of a recently introduced model, the stage model of self-regulated behavioral change (SSBC). In the SSBC, change toward pro-environmental behavior takes place in four, qualitatively different stages (predecisional, preactional, actional, and postactional) which are each influenced by constructs taken from theories previously established to describe and predict pro-environmental behavior. We performed a systematic literature search to retrieve peer-reviewed SSBC-based studies. The review includes 10 studies published between 2013 and 2018, six of which employed a cross-sectional, three an interventional and one a correlational longitudinal design. The cross-sectional and longitudinal studies generally support the model, although there are some irregularities that warrant further investigation. The interventional studies found stage
Pulmonology Advisor offers the latest asthma, COPD, lung cancer, pneumonia news articles for pulmonologists and the healthcare community. Download the FREE app now.
The ICLIO Policy Summit discussion by these diverse stakeholders revealed a 360-degree perspective on the current landscape for the translation of immunotherapy from bench to bedside. Top-level themes from the Summit are highlighted below:. Biomarkers. All stakeholders concur that there is a pressing need to identify biomarkers for immuno-oncology agents in order to address the issue of identifying those patients mostly likely to benefit from being treated with an I-O agent and to help mitigate cost.. Education. New agents are emerging with new mechanisms of action, and combinations and sequencing of immuno-therapy agents are on the horizon. Understanding of side effects, late effects, and long-term effects, and the nuances of immunotherapy delivery for patients in the community continues to evolve. On-going education is imperative, not just for the multidisciplinary oncology team but also for other providers who care for these patients (e.g., primary care, endocrinologists, pulmonologists, ...
ÚZIS ČR plní úkoly Národního zdravotnického informačního systému, provádí sběr a zpracování zdravotnických informací a vedení národních zdravotních registrů.
During the diagnosis or treatment of asthma, you are likely to undergo a number of asthma tests. Learn about them and what their results mean.
Asthma in dogs can be helped by understanding the treatment options available. Learn about the stymptoms, diagnosis and treatment of canine asthma.
... is a disease that affects how you breathe. When you have asthma, it can be difficult to get air in and out of your lungs. ...
So You Have Asthma A GUIDE FOR PATIENTS AND THEIR FAMILIES So You Have Asthma A GUIDE FOR PATIENTS AND THEIR FAMILIES NIH Publication No Originally Printed 2007 Revised March 2013 Contents Overview...1
Please note: The asthma review requirements have changed - see page 36 of the QP guidance for more details You can still claim if no patient has been
2009). "Relationship between cigarette smoking and occupational exposures". Asthma and COPD: Basic Mechanisms and Clinical ... Many people with COPD mistakenly think they have asthma. The distinction between asthma and COPD is made on the basis of the ... In contrast to asthma, the airflow reduction does not improve much with the use of a bronchodilator. Most cases of COPD can be ... Barnes, Peter (2009). Asthma and COPD : basic mechanisms and clinical management (2nd ed.). Academic. p. 837. ISBN 978-0-12- ...
Artikel utama untuk bagian ini adalah: Occupational asthma. Asma sebagai akibat dari (atau yang diperburuk oleh) pajanan tempat ... Third Expert Panel on the Diagnosis and Management of Asthma (2007). Guidelines for the diagnosis and management of asthma. ... a b Shah, R; Saltoun, CA (2012 May-Jun). "Chapter 14: Acute severe asthma (status asthmaticus).". Allergy and asthma ... "Global Strategy for Asthma Management and Prevention" (PDF). Global Initiative for Asthma. 2011. ...
... and performed by pulmonology or occupational medicine physicians.[25] Occupational asthma is much like asthma in that it causes ... Occupational asthma is a worrisome outcome of respiratory sensitization to isocyanates as it can be acutely fatal.[24] ... A quarterly training session on recognizing symptoms of occupational asthma or proper respirator use would be examples of ... Kimber, Ian; Dearman, Rebecca J.; Basketter, David A. (2014-07-25). "Diisocyanates, occupational asthma and IgE antibody: ...
Asthma (Status asthmaticus. Aspirin-induced. Exercise-induced. Bronchiectasis. unspecified. Bronchitis. Bronchiolitis ... occupational. lung disease. Pneumoconiosis Aluminosis. Asbestosis. Baritosis. Bauxite fibrosis. Berylliosis. Caplan's syndrome ... Occupational. Caused by work. Inflammatory disease of the nose causing intermittent and persistent symptoms arising out of ... profuse rhinorrhea, red eyes, periorbital edema, asthma attacks Hormonal. Pregnancy. Nasal congestion present during pregnancy ...
Bardy, J-D.; Malo, J-L.; Seguin, P.; Ghezzo, H.; Desjardins, J.; Dolovich, J.; Cartier, A. (1987). "Occupational Asthma and IgE ... Alemán AM, Quirce S, Bombín C, Sastre J (2001). "[Asthma related to inhalation of Plantago ovata]". Med Clin (Barc) (in Spanish ... Dec 2003). "Psyllium-associated anaphylaxis and death: a case report and review of the literature". Ann Allergy Asthma Immunol ... manufacturing employees who have been exposed to psyllium during the processing have developed occupational asthma and IgE ...
... use is a main source of occupational asthma among users of plastics.[19] Bisphenol A, which is used to manufacture a ...
"Substances causing/worsening asthma". UK Occupational Health and Safety. WorkSafe Victoria. Archived from the original on May ... allergies and asthma". The available data are restricted to these occupational environments. Exposure of the general public to ... a possible cause of asthma) in workplace settings and determined that containers of it should be labeled with "May cause ...
Platts-Mills TA, Longbottom J, Edwards J, Cockroft A, Wilkins S (1987). "Occupational asthma and rhinitis related to laboratory ... "Effect of mouse allergen and rodent environmental intervention on asthma in inner-city children". Annals of Allergy, Asthma & ... Exposure and sensitization to rodent Mup proteins is considered a risk factor for childhood asthma, and is a leading cause of ... Gaffin JM, Phipatanakul W (2009). "The role of indoor allergens in the development of asthma". Current Opinion in Allergy and ...
"Relationship between cigarette smoking and occupational exposures". Asthma and COPD: Basic Mechanisms and Clinical Management ... An outcomes strategy for people with chronic obstructive pulmonary disease (COPD) and asthma in England (PDF). Department of ... Yuh-Chin, T. Huang (2012-10-28). A clinical guide to occupational and environmental lung diseases. [New York]: Humana Press. ... Lötvall, Jan (2011). Advances in combination therapy for asthma and COPD. Chichester, West Sussex: John Wiley & Sons. hlm. 251 ...
Occupational asthma Vandenplas O, Malo JL (November 1997). "Inhalation challenges with agents causing occupational asthma". Eur ... Occupational asthma--the past 50 years". Can Respir J. 11 (1): 21-6. PMID 15010728. Archived from the original on 2004-06-22. ... The specific inhalation challenges has been considered as the gold standard in confirming the diagnosis of occupational asthma ... "Validation of an exposure system to particles for the diagnosis of occupational asthma". Chest. 102 (2): 402-7. doi:10.1378/ ...
Occupational Health and Safety[edit]. Since cannabis is still recognized as an illegal substance under federal law, each state ... Other allergic reactions, such as asthma, rhinitis, conjunctivitis, and cutaneous symptoms have been reported.[118] Workers are ... "Marijuana occupational safety and health , Department of Public Health and Environment". www.colorado.gov. Retrieved 2018-10-30 ...
Patients with a history of neurodermitis, hay fever, or allergic asthma often develop hand eczema. These sicknesses reflect the ... Severe and chronic eczema qualifies as one of the most frequent occupational illnesses. Patients should therefore be referred ... to an occupational-dermatological specialist as soon as possible. ...
Some experts classify RADS as occupational asthma. Those with exposure to highly irritating substances should receive treatment ... These infants may later be confirmed to have asthma following testing. The term is sometimes misused as a synonym for asthma. ... The term reactive airway disease may be used in pediatrics to describe an asthma-like syndrome in infants too young for ... "reactive airways dysfunction syndrome" at Dorland's Medical Dictionary Occupational Allergy. Page 1 Drs Rodney Ehrlich and ...
Respiratory sensitiser - causing occupational asthma Binary ethylenimine, a dimeric form of aziridine "Aziridine" (PDF). Re- ... Mapp CE (2001). "Agents, old and new, causing occupational asthma". Occup. Environ. Med. 58 (5): 354-60. doi:10.1136/oem.58.5. ... Kanerva L, Keskinen H, Autio P, Estlander T, Tuppurainen M, Jolanki R (May 1995). "Occupational respiratory and skin ... "NIOSH Pocket Guide to Chemical Hazards #0274". National Institute for Occupational Safety and Health (NIOSH). Weast, Robert C ...
"Occupational asthma in professional cleaning work: a clinical study". Occupational Medicine. 61 (2): 121-126. doi:10.1093/ ... The allergic symptoms caused by U. botrytis are compatible with rhinitis and asthma; however, U. botrytis was also found in ... Asthma & Immunology Research. 8 (5): 428. doi:10.4168/aair.2016.8.5.428. Curran, P. M. T. (1980). "Ulocladium botrytis (Preuss ...
Occupational asthma Polymer fume fever Chastain, Steve (2004). Metal Casting: A Sand Casting Manual for the Small Foundry. p. 8 ... Cain and Fletcher (2010) report a case of metal fume fever that was diagnosed only by taking a full occupational history and by ... Diagnosis is primarily anecdotal, that is, it depends upon a good occupational history. Diagnosis of metal fume fever can be ... Cain, J. R; Fletcher, R. M (2010). "Diagnosing metal fume fever--an integrated approach". Occupational Medicine. 60 (5): 398- ...
Suh, C. H.; Park, H. S.; Nahm, D. H.; Kim, H. Y. (1998). "Oilseed rape allergy presented as occupational asthma in the grain ... The inhalation of oilseed rape dust may cause asthma in agricultural workers. In 1985, Augusto Odone, with the help of British ...
National Institute for Occupational Safety and Health. Retrieved 7 August 2012. "The National Institute for Occupational Safety ... Asthma is another respiratory illness that many workers are vulnerable to. Workers may also be vulnerable to skin diseases, ... the National Institute for Occupational Safety and Health, which conducts research on occupational health and safety, and the ... Other occupational diseases of concern include carpal tunnel syndrome and lead poisoning. As the number of service sector jobs ...
Instances of occupational rhinitis, dermatitis, and asthma have been reported due to prolonged exposure to tetrazene. "MIL-T- ... Burge, P. S.; Hendy, M.; Hodgson, E. S. (1984). "Occupational asthma, rhinitis, and dermatitis due to tetrazene in a detonator ...
"Fatal Asthma in a Child After Use of an Animal Shampoo Containing Pyrethrin." Western Journal of Medicine. Aug. 2000. Web. " ... Occupational Health Services, Inc. "Pyrethrum." Material Safety Data Sheet. 1 April 1987. New York: OHS, Inc.[unreliable source ... "Review of the Relationship between Pyrethrins, Pyrethroid Exposure and Asthma and Allergies". US Environmental Protection ... "Fatal asthma in a child after use of an animal shampoo containing pyrethrin". The Western journal of medicine. 173 (2): 86-7. ...
Some painters exposed to PPI and related isocyanate chemicals have developed occupational asthma. In chronic toxicity tests, ...
"If 'cedar asthma,' the shingle weaver's occupational disease, does not get him, the steel will. Sooner or later he reaches over ...
Occupational allergy, including asthma, conjunctivitis, and contact dermatitis, has been observed in fish processing workers. ...
Occupational Asthma - An estimated 2% to 5% of all asthma episodes may be caused by exposure to a specific sensitizing agent in ... Nocturnal Asthma - is a characteristic problem in poorly controlled asthma and is reported by more than two thirds of sub- ... Asthma is a common condition and affects over 300 million people around the world. Asthma causes recurring episodes of wheezing ... Asthma is usually triggered by breathing in things in the air such as dust or pollen that produce an allergic reaction. It may ...
September 2006). "Preventing Asthma and Death from MDI Exposure During Spray-on Truck Bed Liner and Related Applications" (PDF ... "NIOSH Pocket Guide to Chemical Hazards #0413". National Institute for Occupational Safety and Health (NIOSH). "Methylene ... The National Institute for Occupational Safety and Health. DHHS (NIOSH) Publication No. 2006-149. Retrieved 2012-08-14. ... from the website of the National Institute for Occupational Safety and Health (NIOSH) Isofact American Chemistry Council ...
"International Journal of Occupational and Environmental Health. 21 (4): 303-07. doi:10.1179/2049396715Y.0000000009. PMC 4727589 ...
Occupational asthma is an occupational lung disease and a type of asthma. Like other types of asthma, it is characterized by ... NIOSH: Prevention of Occupational Asthma Occupational asthma and work aggravated asthma (UK). ... "Occupational asthma". Mayo Clinic. 23 May 2009. "OSH Answers Asthma, Work-related". Canadian Centre for Occupational Health and ... In the United States, occupational asthma is the most common occupational lung disease. Today, asthma affects as much as 15% of ...
Occupational Exposures. All adults with asthma should be questioned about their occupational history and exposures. New ... exposures associated with work-related asthma continue to be recognized. If a patients exposure does not match one of the ...
Occupational asthma is the most common form of occupational lung disease in developed countries. As more new chemicals are ... Occupational asthma. BMJ 2004; 329 doi: https://doi.org/10.1136/bmj.329.7465.558 (Published 02 September 2004) Cite this as: ...
Occupational asthma is a lung disorder in which substances found in the workplace cause the airways of the lungs to swell and ... Many substances in the workplace can trigger asthma symptoms, leading to occupational asthma. The most common triggers are wood ... Occupational asthma is a lung disorder in which substances found in the workplace cause the airways of the lungs to swell and ... Occupational asthma may keep getting worse if you continue to be exposed to the substance that is causing the problem, even if ...
AAAAI experts explain occupational asthma is caused by inhaling fumes, gases, dust or other potentially harmful substances at ... Allergies play a role in many cases of occupational asthma. This type of asthma generally develops only after months or years ... If you think you may have occupational asthma, or if your asthma is not under control, an allergist / immunologist, often ... Occupational asthma is caused by inhaling fumes, gases, dust or other potentially harmful substances while on the job. ...
What to Do When You Get Occupational Asthma. Do you work around chemicals, dust, latex, mold, or animals? If you do, you could ... be at risk for occupational asthma. Triggered by air irritants, this lung disease inflames your airways, making them swell to ...
Prevention of Occupational Asthma. Watch the video on "Research to Inform the Prevention of Asthma in Health Care - Research ... Prevention of Work-related Asthma: Study Search. Welcome to the Prevention of Occupational Asthma: Study Search page! This page ... Tarlo SM, Liss GM.Prevention of occupational asthma. Curr Allergy Asthma Rep. 2010 Jul;10(4):278-86. ... Primary prevention of occupational asthma: identifying and controlling exposures to asthma-causing agents. American Journal of ...
You might have occupational asthma--heres information to help you out. - What is Occupational Asthma? - Asthma at BellaOnline ... BellaOnlines Asthma Editor. What is Occupational Asthma?. What is Occupational Asthma and who s at Risk?. Do you already have ... then you may have developed what is called Occupational Asthma (OA). Occupational asthma is asthma, with all the typical signs ... You ve been diagnosed with occupational asthma, now what?. Once you ve been diagnosed with occupational asthma, it s important ...
Agents associated with the development of occupational asthma and rhinitis are described as being both natural (plant and ... Occupational asthmas and rhinitis are reviewed with respect to causative agents, relevant occupations and workers at risk, ... Occupational asthmas and rhinitis are reviewed with respect to causative agents, relevant occupations and workers at risk, ... Agents associated with the development of occupational asthma and rhinitis are described as being both natural (plant and ...
... should be considered in any new or worsening case of asthma in working-age persons. ... Occupational Asthma Online Medical Reference - discusses inflammation of the sinuses and strategies for management of this ... In general, asthma affects 5% to 10% of people worldwide, and it is estimated that 2% to 15% of asthma may be occupational in ... The definition of occupational asthma (OA), much like the definition of asthma itself, has changed over the years; therefore, ...
Find out how to recognize this common type of asthma. ... substances you come into contact with at work can cause asthma ... Occupational asthma symptoms are similar to those caused by other types of asthma. Signs and symptoms may include:. *Wheezing, ... Occupational asthma is asthma thats caused by breathing in chemical fumes, gases, dust or other substances on the job. ... Diagnosing occupational asthma is similar to diagnosing other types of asthma. However, your doctor will also try to identify ...
Lung function tests were performed because the chest X-ray results were not specific for asthma, and also to assess the ... A study was made of 48 cases of asthma of occupational origin from industrial workers of Madras City over a period of 2 years. ... A study was made of 48 cases of asthma of occupational origin from industrial workers of Madras City over a period of 2 years. ... Lung function tests were performed because the chest X-ray results were not specific for asthma, and also to assess the ...
A case of occupational asthma in a home pieceworker was described. A 67 year old white female was admitted to an emergency ... A case of occupational asthma in a home pieceworker was described. A 67 year old white female was admitted to an emergency ... NIOSH-Author; Case-studies; Bronchial-asthma; Isocyanates; Organic-chemicals; Pulmonary-system-disorders; Clinical-symptoms; ... Content source: National Institute for Occupational Safety and Health Education and Information Division ...
"Occupational asthma". Mayo Clinic. 23 May 2009.. *^ a b c d e f g h i j k l m "OSH Answers Asthma, Work-related". Canadian ... Occupational asthma refers to new onset asthma or the recurrence of previously quiescent asthma directly caused by exposure to ... Occupational asthma is one of the most common occupational lung disease. Approximately 17% of all adult-onset asthma cases are ... It is an occupational lung disease and a type of work-related asthma. Agents that can induce occupational asthma can be grouped ...
10-year occupational health strategy to reduce newly incident cases of occupational asthma (OA) by 30% by 2010 ... RR474 - The true cost of occupational asthma in Great Britain. In 2000 the Health and Safety Commission (HSC) published a long- ... term (10-year) occupational health strategy for Great Britain. The strategy sets an ambitious target for occupational asthma ( ... The study considers solely OA, and does not cover work-aggravated asthma. ...
group is to run a one-day workshop on occupational asthma. The event will be. held on 14 October at Regents College Conference ... feature plenary presentations on how workplace asthma is caused, the impact of. asthma on both employer and employee, and how ... Occupational Health & Wellbeing. Contact us. Features list 2017. Personnel Today Awards. RAD Awards. Whatmedia Recruitment ... cases of asthma are caused directly through occupations or have work as a. significant contributing factor. Most such cases of ...
Occupational asthma. Occupational asthma is asthma caused by some aspect of the workplace environment.2 It is important to ... Diagnosis of occupational asthma. Irritant-induced occupational asthma. The most definitive form of irritant-induced asthma5 is ... Irritant-induced occupational asthma. Workers with occupational asthma induced by exposure to an irritant at work should be ... Sensitizer-induced occupational asthma. For a patient with occupational asthma induced by a respiratory sensitizer, a workers ...
OBJECTIVE: We used data from an existing survey of adults with asthma to identify occupational exposures associated with severe ... DESIGN: Questionnaires were completed by 557 working adults with asthma. Severe exacerbation of asthma in the past 12 mont ... The exacerbation of asthma by workplace conditions is common, but little is known about which agents pose a risk. ... Occupational exposures for the same time period were assessed using an asthma-specific job exposure matrix. We modeled severe ...
The 966 participants were working adults with current asthma who participated in the follow-up phase of the European Community ... Severe exacerbation of asthma was defined as self-reported unplanned care ... The goal of this study was to identify occupational risk factors for severe exacerbation of asthma and estimate the extent to ... Bronchial-asthma; Author Keywords: Asthma; Exacerbation; Occupational; Work-related ...
The article discusses occupational asthma as the most common occupational lung disease in western countries. The disease is ... Occupational asthma: Health crisis in health care workers. // Occupational Health Management;Mar2007, Vol. 17 Issue 3, p25 ... Occupational asthma is a serious problem among health care workers, according to data available in states tracking the disease ... • Sixteen percent of confirmed occupational asthma cases in four states were in health care workers. • Cleaning products ...
of Practice on the control of substances that cause occupational asthma. It. will be an appendix to the new COSHH Regulations ... Grim statistics on occupational asthma. On 1 Jun 2002 in Personnel Today ... Occupational Health & Wellbeing. Contact us. Features list 2018. Personnel Today Awards. The RAD Awards. Whatmedia Recruitment ... asthma because of exposure to substances at work is several times the official. estimates of 1,500-3,000 a year. ...
New insights into neutrophils in the pathogenesis of occupational asthma may provide a novel approach to the individual patient ... in the pathogenesis of occupational asthma may provide a novel approach to the individual patient with occupational asthma. ... Neutrophil activation in occupational asthma Curr Opin Allergy Clin Immunol. 2019 Apr;19(2):81-85. doi: 10.1097/ACI. ... Purpose of review: The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This ...
Defining and investigating occupational asthma: a consensus approach H C Francis, C O Prys-Picard, D Fishwick, C Stenton, P S ... Occupational asthma: an assessment of diagnostic agreement between physicians David Fishwick, Lisa Bradshaw, Mandy Henson, ... Primary prevention of latex related sensitisation and occupational asthma: a systematic review A D LaMontagne, S Radi, D S ... Reported occupational respiratory diseases in Catalonia R Orriols, R Costa, M Albanell, C Alberti, J Castejon, E Monso, R ...
The National Institute for Occupational Safety and Health (NIOSH) reports, They are widely used in the manufacture of flexible ... occupational asthma. polyurethane products. chemical testing. Contact Information. Joseph Frasca. Senior Vice President of ... Isocyanate Exposure Risks & Occupational Asthma Hazards Identified by EMSL. Cinnaminson, NJ - WEBWIRE - Wednesday, July 29, ... EMSL recently sponsored an educational video about exposure risks and occupational asthma associated with isocyanates that can ...
The journal publishes original research articles, review articles, and clinical studies related to asthma, allergy, COPD, non- ... Integrated Approach to Diagnosis of Associated Occupational Asthma and Rhinitis. Sébastien Nguyen,1,2 Roberto Castano,1,2 and ... and occupational asthma (OA).. A 38-year-old woman, who worked as an animal laboratory technician since 2004, first noticed the ... Patients with coexisting work-related rhinitis and asthma would benefit from an adequate and simultaneous recognition of both ...
  • European rhinitis and asthma meeting/symposium on experimental rhinology and immunology of the nose (ERAM/SERIN) 2010 11-13 November 2010, Venice. (wikipedia.org)
  • Severe asthma attacks can be life-threatening. (drugs.com)
  • Severe exacerbation of asthma in the past 12 months was defined as asthma-related hospitalization, or reports of both unplanned asthma care and treatment with a short course of oral corticosteroids. (cdc.gov)
  • RESULTS: A total of 164 participants (29%) were positive for severe exacerbation, and 227 (40.8%) were assessed as being exposed to asthma agents at work. (cdc.gov)
  • The occupational contribution to severe exacerbation of asthma. (cdc.gov)
  • The goal of this study was to identify occupational risk factors for severe exacerbation of asthma and estimate the extent to which occupation contributes to these events. (cdc.gov)
  • Severe exacerbation of asthma was defined as self-reported unplanned care for asthma in the past 12 months. (cdc.gov)
  • These results suggest occupation contributes to approximately one in seven cases of severe exacerbation of asthma in a working population, and various agents play a role. (cdc.gov)
  • A research team led by Hakon Hakonarson, M.D., Ph.D., director of the Center for Applied Genomics at The Children's Hospital of Philadelphia, implicated a location on chromosome 1 associated with moderate-to-severe, childhood-onset asthma. (ohsonline.com)
  • By analyzing a large cohort of children with moderate to severe asthma, all of whom require controller medications on a regular basis, we managed to enrich our study for genetic signals and achieve sufficient statistical power to uncover and replicate a novel asthma gene," Hakonarson said. (ohsonline.com)
  • We also found lower vitamin D intake in the mild asthma group versus the severe group," they added. (fabresearch.org)
  • 3 Occupational asthma affects young and economically active patients and may result in serious respiratory disability, 4, 5 as well as severe socioeconomic consequences. (bmj.com)
  • Associations were stronger when considering those with severe asthma or high symptom score in childhood (OR 0.27 (95% CI 0.11-0.63) and OR 0.49 (95% CI 0.25-0.99), respectively). (ersjournals.com)
  • Results suggest a healthy worker hire effect in subjects with more severe or more symptomatic asthma in childhood. (ersjournals.com)
  • 2 ] who reported a 3% incidence rate of severe asthmatic reactions recorded during 335 specific inhalation challenges with occupational agents. (ersjournals.com)
  • Second, the realistic method may exposed the patient to huge concentrations of particles, resulting in unduly severe asthma attacks. (wikipedia.org)
  • Severe and chronic eczema qualifies as one of the most frequent occupational illnesses. (wikipedia.org)
  • International Severe Asthma Forum (ISAF) 19-21 March 2015, SERIN. (wikipedia.org)
  • It has been used to try to control severe allergic asthma, which does not respond to high doses of corticosteroids. (wikipedia.org)
  • It has been approved for treating people 12 years and older with severe or moderate to severe allergic asthma in more than 90 countries, since its first of such approval in 2002 in Australia. (wikipedia.org)
  • Omalizumab received approval by the U.S. Food and Drug Administration (FDA) in 2003 for treating patients 12 years and older with moderate to severe allergic asthma. (wikipedia.org)
  • It has also received approval in many other countries for treating patients 12 years and older with severe, persistent allergic asthma. (wikipedia.org)
  • Omalizumab was approved by the European Union in 2009 for treating patients 6 to 12 years old with severe, persistent allergic asthma. (wikipedia.org)
  • Thus, its primary use is for patients mostly with severe, persistent allergic asthma, uncontrollable with oral or injectable corticosteroids. (wikipedia.org)
  • The response rates among treated severe "allergic" asthma patients are 60-80% or higher, probably depending on the patient screening procedures used by the various clinical groups of different specialties. (wikipedia.org)
  • Incidents of asthma were so severe for students that some decided to transfer to different schools. (wikipedia.org)
  • Sensitizer-induced occupational asthma immunologic form of asthma which occurs due to inhalation of specific substances (i.e., high-molecular-weight proteins from plants and animal origins, or low-molecular-weight agents that include chemicals, metals and wood dusts) and occurs after a latency period of several weeks to years. (wikipedia.org)
  • Some examples of the more than 250 agents that can cause sensitizer-induced occupational asthma are listed in Table 2 . (cmaj.ca)
  • In France, information on the incidence of occupational asthma in the general working population or in specific occupations is mainly derived from compensation statistics available from the French Sécurité Sociale. (bmj.com)
  • 2 A recent population based follow up study, conducted in Finland, has even estimated that the fraction of asthma incidence attributable to work was 29% for men and 17% for women. (bmj.com)
  • We found a reduced vitamin D intake in both irritant and allergic asthma, in obese and non-obese patients," revealed the team - noting that the average intake in non-obese patients, although higher, did not reach statistical significance. (fabresearch.org)
  • The focus of this article will be allergic asthma. (wikipedia.org)
  • Patients with a history of neurodermitis, hay fever, or allergic asthma often develop hand eczema. (wikipedia.org)
  • Introduction: To investigate the feasibility of improving asthma management - in particular, the implementation of individualised asthma action plans (AAPs) for poorly-controlled adult asthma patients - by providing training in asthma-focused clinical and communication skills for practice nurses. (ebscohost.com)
  • Leukotriene modifiers also fight off some forms of rhinitis , an added bonus for people with asthma. (thefreedictionary.com)
  • About 2 in 5 uninsured and 1 in 9 insured people with asthma could not afford their prescription medication. (ohsonline.com)
  • Improving indoor air quality for people with asthma through measures such as smoke-free air laws and policies, healthy schools, and workplaces. (ohsonline.com)
  • Most people with asthma have wheezing attacks separated by symptom free periods. (hsa.ie)
  • When ozone levels are high, more people with asthma have attacks that require a doctor's attention or use of medication. (wikipedia.org)