Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Anti-Asthmatic Agents: Drugs that are used to treat asthma.Asthma, Exercise-Induced: Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).Administration, Inhalation: The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.Peak Expiratory Flow Rate: Measurement of the maximum rate of airflow attained during a FORCED VITAL CAPACITY determination. Common abbreviations are PEFR and PFR.Asthma, Occupational: Asthma attacks caused, triggered, or exacerbated by OCCUPATIONAL EXPOSURE.Forced Expiratory Volume: Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.Bronchodilator Agents: Agents that cause an increase in the expansion of a bronchus or bronchial tubes.Respiratory Sounds: Noises, normal and abnormal, heard on auscultation over any part of the RESPIRATORY TRACT.Allergens: Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Adrenal Cortex HormonesHypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.Hypersensitivity, Immediate: Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.Respiratory Function Tests: Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.Methacholine Chloride: A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.Spirometry: Measurement of volume of air inhaled or exhaled by the lung.Budesonide: A glucocorticoid used in the management of ASTHMA, the treatment of various skin disorders, and allergic RHINITIS.Eosinophils: Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.Beclomethasone: An anti-inflammatory, synthetic glucocorticoid. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of ASTHMA.Bronchi: The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI.Leukotriene Antagonists: A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.Nebulizers and Vaporizers: Devices that cause a liquid or solid to be converted into an aerosol (spray) or a vapor. It is used in drug administration by inhalation, humidification of ambient air, and in certain analytical instruments.Skin Tests: Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Status Asthmaticus: A sudden intense and continuous aggravation of a state of asthma, marked by dyspnea to the point of exhaustion and collapse and not responding to the usual therapeutic efforts.Bronchoconstrictor Agents: Agents causing the narrowing of the lumen of a bronchus or bronchiole.Airway Remodeling: The structural changes in the number, mass, size and/or composition of the airway tissues.Bronchoconstriction: Narrowing of the caliber of the BRONCHI, physiologically or as a result of pharmacological intervention.Bronchitis: Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Adrenergic beta-Agonists: Drugs that selectively bind to and activate beta-adrenergic receptors.Respiratory Hypersensitivity: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL.Ovalbumin: An albumin obtained from the white of eggs. It is a member of the serpin superfamily.Pyroglyphidae: Family of house dust mites, in the superfamily Analgoidea, order Astigmata. They include the genera Dermatophagoides and Euroglyphus.Pulmonary Medicine: A subspecialty of internal medicine concerned with the study of the RESPIRATORY SYSTEM. It is especially concerned with diagnosis and treatment of diseases and defects of the lungs and bronchial tree.Vital Capacity: The volume of air that is exhaled by a maximal expiration following a maximal inspiration.Asthma, Aspirin-Induced: Asthmatic adverse reaction (e.g., BRONCHOCONSTRICTION) to conventional NSAIDS including aspirin use.Sputum: Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Exhalation: The act of BREATHING out.Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.Air Pollution, Indoor: The contamination of indoor air.Occupational Diseases: Diseases caused by factors involved in one's employment.Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.Mites: Any arthropod of the subclass ACARI except the TICKS. They are minute animals related to the spiders, usually having transparent or semitransparent bodies. They may be parasitic on humans and domestic animals, producing various irritations of the skin (MITE INFESTATIONS). Many mite species are important to human and veterinary medicine as both parasite and vector. Mites also infest plants.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Environmental Exposure: The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Air Pollutants: Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or material. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS.Anti-Inflammatory Agents: Substances that reduce or suppress INFLAMMATION.Breath Tests: Any tests done on exhaled air.Nedocromil: A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.Self Care: Performance of activities or tasks traditionally performed by professional health care providers. The concept includes care of oneself or one's family and friends.Airway Resistance: Physiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow.Androstadienes: Derivatives of the steroid androstane having two double bonds at any site in any of the rings.Metered Dose Inhalers: A small aerosol canister used to release a calibrated amount of medication for inhalation.Interleukin-13: A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-LYMPHOCYTES. It appears to play a role in regulating inflammatory and immune responses.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Respiratory System: The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.Cromolyn Sodium: A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.Th2 Cells: Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.Nitrogen Dioxide: Nitrogen oxide (NO2). A highly poisonous gas. Exposure produces inflammation of lungs that may only cause slight pain or pass unnoticed, but resulting edema several days later may cause death. (From Merck, 11th ed) It is a major atmospheric pollutant that is able to absorb UV light that does not reach the earth's surface.Patient Education as Topic: The teaching or training of patients concerning their own health needs.Ethanolamines: AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Tobacco Smoke Pollution: Contamination of the air by tobacco smoke.Emergency Service, Hospital: Hospital department responsible for the administration and provision of immediate medical or surgical care to the emergency patient.Picornaviridae Infections: Virus diseases caused by the PICORNAVIRIDAE.Cockroaches: Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Hospitalization: The confinement of a patient in a hospital.Toluene 2,4-Diisocyanate: Skin irritant and allergen used in the manufacture of polyurethane foams and other elastomers.Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.Puerto Rico: An island in the Greater Antilles in the West Indies. Its capital is San Juan. It is a self-governing commonwealth in union with the United States. It was discovered by Columbus in 1493 but no colonization was attempted until 1508. It belonged to Spain until ceded to the United States in 1898. It became a commonwealth with autonomy in internal affairs in 1952. Columbus named the island San Juan for St. John's Day, the Monday he arrived, and the bay Puerto Rico, rich harbor. The island became Puerto Rico officially in 1932. (From Webster's New Geographical Dictionary, 1988, p987 & Room, Brewer's Dictionary of Names, 1992, p436)Aerosols: Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.Adrenergic beta-2 Receptor Agonists: Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS.Pregnenediones: Unsaturated pregnane derivatives containing two keto groups on side chains or ring structures.Urban Population: The inhabitants of a city or town, including metropolitan areas and suburban areas.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Eosinophil Cationic Protein: One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil cationic protein is a 21-kDa cytotoxic peptide with a pI of 10.9. Although eosinophil cationic protein is considered a member of the RNAse A superfamily of proteins, it has only limited RNAse activity.Occupational Exposure: The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Anti-Allergic Agents: Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)Practice Guidelines as Topic: Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.Interleukin-5: A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.Pulmonary Eosinophilia: A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.Respiratory Mucosa: The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.Air Pollution: The presence of contaminants or pollutant substances in the air (AIR POLLUTANTS) that interfere with human health or welfare, or produce other harmful environmental effects. The substances may include GASES; PARTICULATE MATTER; or volatile ORGANIC CHEMICALS.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Rhinovirus: A genus of PICORNAVIRIDAE inhabiting primarily the respiratory tract of mammalian hosts. It includes over 100 human serotypes associated with the COMMON COLD.Mucus: The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.Housing: Living facilities for humans.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Acute Disease: Disease having a short and relatively severe course.Ozone: The unstable triatomic form of oxygen, O3. It is a powerful oxidant that is produced for various chemical and industrial uses. Its production is also catalyzed in the ATMOSPHERE by ULTRAVIOLET RAY irradiation of oxygen or other ozone precursors such as VOLATILE ORGANIC COMPOUNDS and NITROGEN OXIDES. About 90% of the ozone in the atmosphere exists in the stratosphere (STRATOSPHERIC OZONE).Respiratory Tract DiseasesFenoterol: An adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.Isocyanates: Organic compounds that contain the -NCO radical.Health Surveys: A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Antigens, Dermatophagoides: Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They are proteins, found in mite feces or mite extracts, that can cause ASTHMA and other allergic diseases such as perennial rhinitis (RHINITIS, ALLERGIC, PERENNIAL) and atopic dermatitis (DERMATITIS, ATOPIC). More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the above two species, are among the strongest mite immunogens in humans.Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.Patient Compliance: Voluntary cooperation of the patient in following a prescribed regimen.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.QuinolinesSinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.Parents: Persons functioning as natural, adoptive, or substitute parents. The heading includes the concept of parenthood as well as preparation for becoming a parent.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Bronchoscopy: Endoscopic examination, therapy or surgery of the bronchi.Vehicle Emissions: Gases, fumes, vapors, and odors escaping from the cylinders of a gasoline or diesel internal-combustion engine. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Random House Unabridged Dictionary, 2d ed)Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Urban Health: The status of health in urban populations.Ipratropium: A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Mice, Inbred BALB CLung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.Conjunctivitis, Allergic: Conjunctivitis due to hypersensitivity to various allergens.United StatesPollen: The fertilizing element of plants that contains the male GAMETOPHYTES.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Leukocyte Count: The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.Acetates: Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.Forced Expiratory Flow Rates: The rate of airflow measured during a FORCED VITAL CAPACITY determination.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Disease Management: A broad approach to appropriate coordination of the entire disease treatment process that often involves shifting away from more expensive inpatient and acute care to areas such as preventive medicine, patient counseling and education, and outpatient care. This concept includes implications of appropriate versus inappropriate therapy on the overall cost and clinical outcome of a particular disease. (From Hosp Pharm 1995 Jul;30(7):596)Desensitization, Immunologic: Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Leukotriene E4: A biologically active principle of SRS-A that is formed from LEUKOTRIENE D4 via a peptidase reaction that removes the glycine residue. The biological actions of LTE4 are similar to LTC4 and LTD4. (From Dictionary of Prostaglandins and Related Compounds, 1990)New Zealand: A group of islands in the southwest Pacific. Its capital is Wellington. It was discovered by the Dutch explorer Abel Tasman in 1642 and circumnavigated by Cook in 1769. Colonized in 1840 by the New Zealand Company, it became a British crown colony in 1840 until 1907 when colonial status was terminated. New Zealand is a partly anglicized form of the original Dutch name Nieuw Zeeland, new sea land, possibly with reference to the Dutch province of Zeeland. (From Webster's New Geographical Dictionary, 1988, p842 & Room, Brewer's Dictionary of Names, 1992, p378)MichiganGuideline Adherence: Conformity in fulfilling or following official, recognized, or institutional requirements, guidelines, recommendations, protocols, pathways, or other standards.Absenteeism: Chronic absence from work or other duty.Dyspnea: Difficult or labored breathing.Leukotrienes: A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.Food Hypersensitivity: Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food.Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Goblet Cells: A glandular epithelial cell or a unicellular gland. Goblet cells secrete MUCUS. They are scattered in the epithelial linings of many organs, especially the SMALL INTESTINE and the RESPIRATORY TRACT.Inhalation Spacers: A variety of devices used in conjunction with METERED DOSE INHALERS. Their purpose is to hold the released medication for inhalation and make it easy for the patients to inhale the metered dose of medication into their lungs.Age of Onset: The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.Infant, Newborn: An infant during the first month after birth.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Interleukin-4: A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.Medication Adherence: Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.Chemokine CCL11: A CC-type chemokine that is specific for CCR3 RECEPTORS. It is a potent chemoattractant for EOSINOPHILS.Cost of Illness: The personal cost of acute or chronic disease. The cost to the patient may be an economic, social, or psychological cost or personal loss to self, family, or immediate community. The cost of illness may be reflected in absenteeism, productivity, response to treatment, peace of mind, or QUALITY OF LIFE. It differs from HEALTH CARE COSTS, meaning the societal cost of providing services related to the delivery of health care, rather than personal impact on individuals.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Polymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Pneumonia: Infection of the lung often accompanied by inflammation.Nasal Polyps: Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.Cross-Over Studies: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

Physical characterization of a low-charge glycoform of the MUC5B mucin comprising the gel-phase of an asthmatic respiratory mucous plug. (1/13648)

We have previously noted that sequential extraction of an asthmatic mucous exudate with 6 M guanidinium chloride yielded a fraction of the mucins that were most resistant to solubilization and of high Mr [Sheehan, Richardson, Fung, Howard and Thornton (1995) Am. J. Respir. Cell Mol. Biol. 13, 748-756]. Here we show that this mucin fraction is dominated (at least 96% of the total) by the low-charge glycoform of the MUC5B gene product. Seen in the electron microscope the mucins appeared mainly as compact 'island' structures composed of linear threads often emanating from globular 'nodes' rather than the discrete linear threads more typical of mucins that we have previously described. The effect of reducing agents was as expected for other gel-forming mucins, i.e. reduced subunits or monomers of Mr 3x10(6)) were produced within 15 min of treatment. Kinetic experiments on the cleavage of the intact mucins with the proteinase trypsin indicated two clear regimes of fragmentation. An initial rapid cleavage generated mucins ranging from Mr=4x10(6) to 30x10(6) that in the electron microscope appeared as polydisperse threads (500-3000 nm in length), similar to normal and other respiratory mucins that we have previously characterized. A subsequent slower fragmentation over many hours yielded a major fragment of Mr 3x10(6) and length 200-600 nm, very similar in size and Mr to the subunits obtained by reduction. The results suggest that the MUC5B mucin is assembled, first into polydisperse linear threads, which are then linked together via a protein-mediated process. This might involve part of the mucin polypeptide or an as yet unidentified protein(s). The high proteinase susceptibility of the linkage suggests that it might be a point of control for mucin size and thus mucus rheology.  (+info)

Respiratory symptoms among glass bottle workers--cough and airways irritancy syndrome? (2/13648)

Glass bottle workers have been shown to experience an excess of respiratory symptoms. This work describes in detail the symptoms reported by a cohort of 69 symptomatic glass bottle workers. Symptoms, employment history and clinical investigations including radiology, spirometry and serial peak expiratory flow rate records were retrospectively analyzed from clinical records. The results showed a consistent syndrome of work-related eye, nose and throat irritation followed after a variable period by shortness of breath. The latent interval between starting work and first developing symptoms was typically 4 years (median = 4 yrs; range = 0-28). The interval preceding the development of dysponea was longer and much more variable (median = 16 yrs; range = 3-40). Spirometry was not markedly abnormal in the group but 57% of workers had abnormal serial peak expiratory flow rate charts. Workers in this industry experience upper and lower respiratory tract symptoms consistent with irritant exposure. The long-term functional significance of these symptoms should be formally investigated.  (+info)

Asthma visits to emergency rooms and soybean unloading in the harbors of Valencia and A Coruna, Spain. (3/13648)

Soybean unloading in the harbor of Barcelona, Spain, has been associated with large increases in the numbers of asthma patients treated in emergency departments between 1981 and 1987. In this study, the association between asthma and soybean unloading in two other Spanish cities, Valencia and A Coruna, was assessed. Asthma admissions were retrospectively identified for the period 1993-1995, and harbor activities were investigated in each location. Two approaches were used to assess the association between asthma and soybean unloading: One used unusual asthma days (days with an unusually high number of emergency room asthma visits) as an effect measure, and the other estimated the relative increase in the daily number of emergency room visits by autoregressive Poisson regression, adjusted for meteorologic variables, seasonality, and influenza incidence. No association between unusual asthma days and soya unloading was observed in either Valencia or A Coruna, except for one particular dock in Valencia. When the association between unloaded products and the daily number of emergency asthma visits was studied, a statistically significant association was observed for unloading of soya husk (relative risk = 1.50, 95% confidence interval 1.16-1.94) and soybeans (relative risk = 1.31, 95% confidence interval 1.08-1.59) in A Coruna. In Valencia, a statistical association was found only for the unloading of soybeans at two particular docks. Although these findings support the notion that asthma outbreaks are not a common hidden condition in most harbors where soybeans are unloaded, the weak associations reported are likely to be causal. Therefore, appropriate control measures should be implemented to avoid soybean dust emissions, particularly in harbors with populations living in the vicinity.  (+info)

Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy. (4/13648)

The aim of the present study was to investigate bronchoprotective sensitivity in patients receiving regular treatment with short- and long-acting beta2-agonists and to evaluate any possible association with genetic polymorphism. Thirty-eight patients with stable mild to moderate asthma and receiving inhaled corticosteroids were randomized in a parallel group, double-blind, double-dummy fashion to receive 2 weeks of treatment with either formoterol (12 microg once daily, 6 microg twice daily or 24 microg twice daily) or terbutaline (500 microg four times daily). Bronchoprotection against methacholine challenge (as a provocative dose to produce a 20% fall in forced expiratory volume in 1.0 s: PD20) was measured at baseline (unprotected) after an initial 1 week run-in without beta2-agonist, and at 1 h after the first and last doses of each treatment. The PD20 values were log-transformed and calculated as change from baseline. Percentage desensitization of log PD20 for first- versus last-dose bronchoprotection was calculated and analysed according to effects of treatment and beta2-adrenoceptor polymorphism at codon 16 or 27. The mean degree of desensitization for bronchoprotection was comparable with all four treatments and there were no significant differences in absolute PD20 values after 2 weeks of chronic dosing. The PD20 values were (as microg of methacholine, geometric means+/-S. E.M.): formoterol, 12 microg once daily, 99+/-42 microg; formoterol, 6 microg twice daily, 107+/-44 microg; formoterol, 24 microg twice daily, 108+/-45 microg; terbutaline, 500 microg four times daily, 88+/-37 microg. All patients receiving formoterol, 24 microg twice daily, exhibited a loss of protection greater than 30% which was unrelated to polymorphism at codon 16 or 27. For codon 16, the use of lower doses of formoterol (12 microg once daily or 6 microg twice daily) showed wider variability in the propensity for protection loss in patients who were heterozygous, in contrast to a more uniform protection loss seen with homozygous glycine patients. The amount of protection loss was not significantly related to polymorphism at codon 16 or 27, expressed as values (mean+/-S.E.M.) for percentage desensitization according to each genotype (pooled treatments): Gly-16, 66+/-11%; Het-16, 53+/-8%; Arg-16, 69+/-18%; Glu-27, 68+/-12%; Het-27, 58+/-8%; Gln-27, 52+/-12%. The results of this preliminary study showed that bronchoprotective desensitization occurred readily in response to short- or long-acting beta2-agonist exposure irrespective of beta2-adrenoceptor polymorphism at codon 16 or 27. Further studies with larger patient numbers are required to further evaluate the effects of polymorphisms with lower doses of regular formoterol.  (+info)

Management of asthma and COPD patients: feasibility of the application of guidelines in general practice. (5/13648)

OBJECTIVE: To examine the feasibility of the application of guidelines to the management of asthma and chronic obstructive pulmonary disease (COPD) by assessing compliance with the guidelines and listing the barriers general practitioners (GPs) encountered during implementation. Insight into the feasibility of individual items in the guidelines can guide implementation strategies in the future and, if necessary, support revision of the guidelines. DESIGN: Descriptive study of care delivered during the implementation of guidelines by means of documentation of the care provided, education, feedback on compliance and peer review. SETTING: General practice. STUDY PARTICIPANTS: Sixteen GPs in 14 general practices. MAIN OUTCOME MEASURES: Compliance was expressed as the percentage of patients per practice managed by the GPs according to the guidelines. For each patient (n=413) data were collected on the care delivered during the first year of the implementation. Barriers encountered were derived from the summaries of the discussions held during the monthly meetings. RESULTS: The GPs were most compliant on the items 'PEFR measurement at every consultation' (98%), 'allergy test' (78%) and 'advice to stop smoking' (82%), and less compliant on the items 'four or more consultations a year' (46%), 'ordering spirometry' (33%), 'adjustment of medication' (42%), 'check on inhalation technique' (38%) and referral to a chest physician (17%) or a district nurse (5%). The main barriers were the amount of time to be invested, doubts about the necessity of regular consultations and about the indications for ordering spirometry and for referral to a chest physician or a district nurse. CONCLUSION: Although the feasibility was assessed in a fairly optimal situation, compliance with the guidelines was not maximal, and differed between the individual items of care. Suggestions are given for further improvements in compliance with the guidelines and for revision of the guidelines.  (+info)

Elevated asthma morbidity in Puerto Rican children: a review of possible risk and prognostic factors. (6/13648)

Latino children represent a significant proportion of all US children, and asthma is the most common chronic illness affecting them. Previous research has revealed surprising differences in health among Latino children with asthma of varying countries of family origin. For instance, Puerto Rican children have a higher prevalence of asthma than Mexican American or Cuban American children. In addition, there are important differences in family structure and socioeconomic status among these Latino populations: Cuban Americans have higher levels of education and family income than Mexican-Americans and Puerto Ricans; mainland Puerto Rican children have the highest proportion of households led by a single mother. Our review of past research documents differences in asthma outcomes among Latino children and identifies the possible genetic, environmental, and health care factors associated with these differences. Based on this review, we propose research studies designed to differentiate between mutable and immutable risk and prognostic factors. We also propose that the sociocultural milieus of Latino subgroups of different ethnic and geographic origin are associated with varying patterns of risk factors that in turn lead to different morbidity patterns. Our analysis provides a blue-print for future research, policy development, and the evaluation of multifactorial interventions involving the collaboration of multiple social sectors, such as health care, public health, education, and public and private agencies.  (+info)

Cockroach allergy and asthma in a 30-year-old man. (7/13648)

A growing body of evidence has implicated allergens derived from cockroaches as an important environmental factor that may aggravate asthma in sensitized persons. We present the case of a 30-year-old man with asthma and a cockroach allergy. Allergy skin testing confirmed hypersensitivity to cockroach extract, and a home visit revealed visual evidence of infestation and the presence of Bla g 1 German cockroach allergen in vacuumed dust. As is typical of patients with a cockroach allergy and asthma, multiple factors in addition to cockroach allergen appeared to aggravate the patient's asthma. A multimodality therapeutic regimen, which included medications as well as cleaning of the home, integrated pest management, and professional application of chemical controls, resulted in substantial clinical improvement. The pathophysiology, epidemiology, and clinical features of cockroach-allergic asthma are reviewed, and an approach to diagnosis and management is suggested.  (+info)

Short-term associations between outdoor air pollution and visits to accident and emergency departments in London for respiratory complaints. (8/13648)

Many epidemiological studies have shown positive short-term associations between health and current levels of outdoor air pollution. The aim of this study was to investigate the association between air pollution and the number of visits to accident and emergency (A&E) departments in London for respiratory complaints. A&E visits include the less severe cases of acute respiratory disease and are unrestricted by bed availability. Daily counts of visits to 12 London A&E departments for asthma, other respiratory complaints, and both combined for a number of age groups were constructed from manual registers of visits for the period 1992-1994. A Poisson regression allowing for seasonal patterns, meteorological conditions and influenza epidemics was used to assess the associations between the number of visits and six pollutants: nitrogen dioxide, ozone, sulphur dioxide, carbon monoxide, and particles measured as black smoke (BS) and particles with a median aerodynamic diameter of <10 microm (PM10). After making an allowance for the multiplicity of tests, there remained strong associations between visits for all respiratory complaints and increases in SO2: a 2.8% (95% confidence interval (CI) 0.7-4.9) increase in the number of visits for a 18 microg x (-3) increase (10th-90th percentile range) and a 3.0% (95% CI 0.8-5.2) increase for a 31 microg x m(-3) increase in PM10. There were also significant associations between visits for asthma and SO2, NO2 and PM10. No significant associations between O3 and any of the respiratory complaints investigated were found. Because of the strong correlation between pollutants, it was difficult to identify a single pollutant responsible for the associations found in the analyses. This study suggests that the levels of air pollution currently experienced in London are linked to short-term increases in the number of people visiting accident and emergency departments with respiratory complaints.  (+info)

The overall goal of the Severe Asthma Research Program (SARP) is to develop a new paradigm for the understanding of severe asthma and its sub-phenotypes, in chi...
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Data & statistics on Current Asthma Status by Health Care Utilization Colorado Adults BRFSS: Current Asthma Status by Health Care Utilization: Colorado Adults, BRFSS 2000, To the right breaks down the prevalence of COPD among Colorado adults by age, race/ethnicity, sex, employment status, education level, income, marital status, smoking status, and asthma history., Urgent care visits: Percent of adults currently with asthma who had at least one urgent care visit for asthma with their provider in the past 12 months by State, District of Columbia and U.S. Territory, 2003...
The Asthma USA survey showed that uncontrolled asthma had significant medical consequences. Adults with uncontrolled asthma were more prone to need treatment with oral corticosteroids, visit the emergency room, or be hospitalized, compared with patients with well-controlled asthma.. Children with uncontrolled asthma also were in the same situation. Earlier studies have shown that uncontrolled asthma can put patients at risk for increased asthma symptoms, sudden asthma attacks, hospitalization, and even death.. The survey included >81,500 households that were assessed using the Asthma Control Test (ACT). Of the >10,000 adults with self-reported asthma taking the ACT, 41% had a score of 19 or less, which indicates uncontrolled asthma. The survey also examined scores from the Childhood Asthma Control Test and ACT in >3000 children respondents between the ages of 4 and 17. The results indicated that 31% of the children with asthma between the ages of 4 and 11 and 25% of those between the ages of 12 ...
Updated guidelines and new treatments for asthma have become available since the last major survey of asthma management in the United States was completed ∼11 years ago. The Asthma Insight and Management (AIM) survey was conducted to assess the current status of asthma burden in the United States. A geographically stratified screening of 60,682 households provided a national sample of 2500 patients with current asthma (2186 adults aged ≥18 years; 314 adolescents aged 12‐17 years). A national sample of 1004 adults without current asthma was interviewed for comparison with the adult asthma population, and 309 asthma health care providers were surveyed for their opinions about the burden of asthma. Asthma prevalence in the United States was estimated at 8%. Twice as many adult asthma patients rated their health as "only fair," "poor," or "very poor," or experienced limitations in activity because of health problems, compared with the general population. Asthma also frequently caused negative ...
Asthma is a prevalent chronic respiratory disease and major cause of morbidity in the United States (1). However, with appropriate medication, medical care, and self-management, most asthma symptoms are preventable (2). Recent evidence indicates that asthma self-management education is effective in improving outcomes of chronic asthma (3). Guidelines issued by the National Asthma Education and Prevention Program (NAEPP) specify essential components of asthma management, including patient education, objective monitoring of symptoms, and avoiding asthma triggers (3). Healthy People 2010 objectives include increasing the proportion of persons with asthma who receive formal patient education from 8% to 30% (objective 24-6) and who receive care according to NAEPP guidelines (objective 24-7) (4,5). The National Health Interview Survey (NHIS) routinely includes questions that assess asthma status. In 2003, the survey included a series of questions designed to reflect clinical best practices for asthma ...
TY - JOUR. T1 - The Role of the Six-minute Walk Test, Pulmonary Function Test, and Asthma Control Test in Asthmatic Patients-a Preliminary Report. AU - Chen, Shiau-Yee. AU - Hsu, Han Lin. AU - Lin, Jiu Jenq. AU - 余, 明治(Ming-Chi Yu). AU - 江, 玲玲(Ling-Ling Chiang). AU - 李, 俊年(Chun-Nie Lee). PY - 2010. Y1 - 2010. N2 - Purpose: Asthma control is the main concern for related professionals when approaching asthmatic patients. In this study, we selected three different tools to understand asthma control status in patients with asthma.Methods: Twenty-six patients with asthma were recruited in the study. These patients underwent pulmonary function testing with spirometry and the six-minute walk test, and completed an asthma control questionnaire (Asthma Control Test, ACT). In statistical analysis, the Spearman rank correlation and Pearson correlation coefficient were used for correlation between measured variables. For explanation, potential prediction variables were entered into a ...
The phenotypic features of asthma differ by severity and with advancing age. With advancing age, patients with severe asthma are more obese, have greater airflow limitation, less allergen sensitization, and variable type 2 inflammation. Novel mechanisms besides type 2 inflammatory pathways may infor …
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By Jaclyn Chasse N.D.. Over 22 million Americans have asthma and it is one of the most common pediatric chronic diseases, affecting about 6 million children. Asthma is a condition characterized by cough, difficulty breathing, wheezing and chest tightness. Asthma has several underlying pathological mechanisms including bronchoconstriction, bronchial hyperreactivity, and underlying inflammation and airway edema.. The National Asthma Education and Prevention Program (NAEPP) first published guidelines for care in 1991 and published the most recent update in 2007. One of the key clinical activities recommended by the NAEPP is the development of a written asthma action plan in partnership with the patient. An asthma action plan is a written tool which outlines appropriate care for an asthma patient. The stoplight tool is on example of a written asthma action plan that categorizes severity of asthma into a red, yellow, or green zone. Each zone corresponds with a different stage of asthma and outlines ...
BackgroundMany patients and healthcare professionals believe that work-related psychosocial stress, such as job strain, can make asthma worse, but this is not corroborated by empirical evidence. We investigated the associations between job strain and the incidence of severe asthma exacerbations in working-age European men and women. MethodsWe analysed individual-level data, collected between 1985 and 2010, from 102 175 working-age men and women in 11 prospective European studies. Job strain (a combination of high demands and low control at work) was self-reported at baseline. Incident severe asthma exacerbations were ascertained from national hospitalization and death registries. Associations between job strain and asthma exacerbations were modelled using Cox regression and the study-specific findings combined using random-effects meta-analyses. ResultsDuring a median follow-up of 10years, 1 109 individuals experienced a severe asthma exacerbation (430 with asthma as the primary diagnostic ...
As co-Editors in Chief (and Professor Canonica as President of Interasma), it is our pleasure to welcome our colleagues to this first issue of the journal Asthma Research and Practice (ARP) [1]. This will be an open-access online journal, and thus easily accessible to a large audience. The aims and scope of ARP will be to publish original research articles and state of the art reviews focusing on risk factors, diagnosis and management of asthma at all ages. Since asthma is a disease that comprises diverse endotypes and is often accompanied by co-morbidities, we expect and welcome manuscripts on topics such as "obese asthma", exercise-induced asthma, asthma-COPD overlap syndrome, occupational asthma, and others [2, 3]. Although existing journals in fields as diverse as paediatrics, internal medicine, allergy and pulmonology include articles on asthma, we believe that a journal entirely dedicated to asthma is both valuable and necessary. Moreover, we are committed to have a section devoted ...
We have previously shown that atopic mechanisms may account for, at most, "only" 40% of cases of asthma in the general population.4 Interestingly, in this review we have shown that, at most, "only" 50% of all asthma cases are attributable to eosinophilic airway inflammation. Thus, evidence from studies of eosinophilia and asthma is consistent with that from studies of atopy and asthma: in both instances, at most about 50% of asthma cases appear to be due to "allergic" mechanisms (whether these are defined in terms of atopy or in terms of eosinophilia). This further adds to the evidence that allergic mechanisms may not be the only and/or necessarily the most important underlying mechanism for asthma. Non-eosinophilic asthma is associated with neutrophilic responses not only in severe asthmatics but also in those with moderate and mild asthma, and we thus hypothesise that a major proportion of asthma is based on neutrophilic airway inflammation. Environmental exposure to bacterial endotoxin, ...
Mild and Severe Asthma May Be 2 Diseases The authors of a study reported recently in the European Respiratory Journal have concluded that severe asthma and mild asthma may be different conditions with different inflammatory processes. The study, conducted by scientists across Europe, evaluated 321 patients, 158 with mild-to-moderate asthma and 163 with severe asthma. The results of the study showed that both groups had very different levels of key chemicals in their blood. Also, whereas more men suffered from asthma, women were 4 times as likely to suffer from severe asthma. Individuals with mild-to-moderate asthma were able to control their symptoms with low doses of inhaled corticosteroids. Very few with severe asthma, however, were able to have their symptoms treated despite being treated with heavier doses of drugs. ...
The Particulars: Research shows that chronic asthma and cardiovascular disease (CVD) share a common inflammatory pathophysiology. However, few studies have explored the potential association between persistent asthma-defined as requiring daily controller medications-and an increased risk of CVD.. Data Breakdown: Researchers compared the rates of CVD over 9 years among patients with persistent asthma, intermittent asthma, or no asthma for a study. Among those with persistent asthma, 84.1% were alive and free from CVD, compared with a 91.1% rate for those with intermittent asthma and a 90.2% rate for those without asthma. Patients with persistent asthma had about a 60.0% higher risk of CVD events that those without asthma.. Take Home Pearl: There appears to be a strong association between persistent asthma and risk for CVD. ...
A stranger would never guess my friend Catrina has asthma. She plays three varsity sports, sings along to entire musicals without losing her breath, and overall leads an active, nonstop life. Because of the incredible advancements in asthma treatment, Catrina seems practically indistinguishable from someone without asthma. Even I have never seen her reach for her inhaler. It is only because of our close friendship that I know she takes medicine to control her asthma and frequently visits an allergist. How has asthma treatment come so far? The use of animals in asthma research has lead to many groundbreaking discoveries that have benefited asthma sufferers like Catrina. Early asthma studies relied on animal research, and so does the current research that develops the kind of new medicines that Catrina uses today.. Asthma is defined by the National Institutes of Health as a "chronic lung disease that inflames and narrows the airways", with symptoms of "recurring periods of wheezing, tightness, ...
TY - JOUR. T1 - Management of asthma exacerbations. AU - Chestnutt, Mark. PY - 2002/1/1. Y1 - 2002/1/1. N2 - The 1997 Expert Panel Report 2 from the National Asthma Education and Prevention Program* details principles and goals for managing asthma exacerbations, based on scientific literature and the opinion of the panel. The panels recommendations are summarized here, along with approaches to the evaluation and management of patients with asthma exacerbations. Methods to assess and classify the severity of asthma exacerbations are discussed, and treatment objectives for mild, moderate, and severe exacerbations are presented, along with a discussion of postinfectious acute airway hyperresponsiveness. A review of pharmacologic agents used in the treatment of asthma exacerbations is also included. Key points in the management of asthma exacerbations include the notion that early treatment is the best strategy for management. Important elements of early treatment include recognition of early signs ...
... The Community Asthma Program provides free asthma self-management education and support for children and young people with asthma and their families.. The program is aimed at people who frequently attend an Emergency Department for help with asthma, are at risk of attending or have complex psychosocial needs impacting on their ability to self-manage their asthma.. Families entering the program receive one-on-one help and support from a qualified health professional with advanced skills in asthma and respiratory education.. Click on the links below for further information: ...
Accordingly, the new update of the Global Initiative for Asthma (GINA) guidelines 2006 is based on the control of the disease and attempts to quantify and graduate the level of control by using a classification of asthmatic subjects into controlled,partly controlled and uncontrolled groups.. Achieving and maintaining optimal asthma control is a major goal of asthma management. Although the results of clinical trials advocate that asthma control can be reached in most patients, there is evidence that many subjects with asthma have poorly controlled disease and that there is a significant gap between the treatment goals and the current level of asthma control achieved in the general population.. The aim of this study is to assess the prevalence of uncontrolled and partly controlled asthma in Italy using a patient-based tool such as Asthma Control Test. ...
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Asthma Surveillance Abstract: Asthma Surveillance (Asthma GIS Maps) The Burden of Asthma in Connecticut 2012 Surveillance Report Asthma is a chronic disease of the respiratory system that is characterized by reversible obstruction of the airways and airway hyper-responsiveness to a variety of stimuli. Left uncontrolled or poorly-managed, asthma can lead to emergency department visits, hospitalization, or death. In 2010, 18.7 million adults and 7 million children in the United States had asthma. Asthma prevalence in Connecticut adults and children has been higher than national prevalence rates since the year 2000. In Connecticut, the populations disproportionately affected by asthma are: children, females, Hispanics, non-Hispanic Blacks, and residents of CTs five largest cities.Custom Download Select specific sections of The Burden of Asthma in ConnecticutFull Version Download the complete version of The Burden of Asthma in Connecticut Updated Report Tables (2016): Table F-1: Asthma Hospitalization
Results. A total of 4.8% of children had atopic asthma, 1.9% had nonatopic asthma, 3.4% had resolved asthma, and 4.3% had frequent respiratory symptoms. Mean BMI was higher among children with nonatopic asthma, whereas prenatal maternal smoking was a risk factor for resolved asthma. Atopic and nonatopic asthma were similar for most measures of asthma severity (eg, medication use and lung function), and relatively few children in either group were receiving inhaled corticosteroids (5%-10%). Patients with resolved asthma had fewer symptoms but lung-function impairment similar to that seen with current asthma, whereas children with frequent respiratory symptoms but no asthma diagnosis had normal lung function. ...
If you or your child has asthma that requires daily treatment, it is important to have an asthma action plan. An asthma action plan is a written plan that tells you what asthma medicine to take every day and how to treat an asthma attack. It can help you make quick decisions in case you are not able to think clearly during an attack.. An asthma action plan usually includes:. ...
TY - JOUR. T1 - Measures of asthma control. AU - Bime, Christian. AU - Nguyen, Jessica. AU - Wise, Robert A.. PY - 2012/1/1. Y1 - 2012/1/1. N2 - Purpose of Review: Over the past decade, the concept of asthma control as distinct from asthma severity has been clearly defined. Well controlled asthma is the goal of therapy in all asthma patients. This review is a comprehensive description of the tools currently available for a methodical assessment of different aspects of asthma control in clinical practice and research. Recent Findings: Several questionnaires for assessing asthma control have been extensively validated in adults. In children, validation data are less extensive. Considerable overlap exists between asthma control measures and measures of asthma-specific quality of life. Asthma-specific quality-of-life questionnaires have been used as primary outcome measures in major clinical trials evaluating asthma therapy. Biomarkers that reflect eosinophilic inflammation of the airways are used ...
About Severe Asthma. Asthma affects 315 million individuals worldwide, and up to 10% of asthma patients have severe asthma, which may be uncontrolled despite high doses of standard-of-care asthma controller medicines and can require the use of chronic oral corticosteroids (OCS).. Severe, uncontrolled asthma is debilitating and potentially fatal with patients experiencing frequent exacerbations and significant limitations on lung function and quality of life. Severe, uncontrolled asthma has an eight times higher risk of mortality than severe asthma.. Severe, uncontrolled asthma can lead to a dependence on OCS, with systemic steroid exposure potentially leading to serious short- and long-term adverse effects, including weight gain, diabetes, osteoporosis, glaucoma, anxiety, depression, cardiovascular disease and immunosuppression. There is also a significant physical and socio-economic burden of severe, uncontrolled asthma with these patients accounting for 50% of asthma-related costs.. About the ...
KLING, S et al. Guideline for the management of acute asthma in children: 2013 update - Part 3: March 2013. SAMJ, S. Afr. med. j. [online]. 2013, vol.103, n.3, pp.199-207. ISSN 2078-5135.. BACKGROUND: Acute asthma exacerbations remain a common cause of hospitalisation and healthcare utilisation in South African children. AIM: To update the South African paediatric acute asthma guidelines according to current evidence, and produce separate recommendations for children above and below 2 years of age. METHODS: A working group of the South African Childhood Asthma Group was established to review the published literature on acute asthma in children from 2000 to 2012, and to revise the South African guidelines accordingly. RECOMMENDATIONS: Short-acting inhaled bronchodilators remain the first-line treatment of acute asthma. A metered dose inhaler with spacer is preferable to nebulisation for bronchodilator therapy to treat mild to moderate asthma. Two to four puffs of a short-acting bronchodilator ...
Asthma symptoms were recorded by the patient each morning and evening in the asthma daily diary. Symptoms were recorded using a scale of 0-3, where 0 indicates no asthma symptoms. The daily asthma symptom total score was calculated by taking the sum of the daytime score recorded in the evening and the nighttime score recorded the following morning. The weekly total asthma score was averaged from the daily scores over a 7 day period, with score ranging from 0 to 6, where 0 indicates no asthma symptoms. The changes from baseline of weekly total asthma score are compared between benralizumab 30 mg Q4W and placebo by using the mixed-effect model repeated measures (MMRM) with baseline blood eosinophil count (≥300 cells/μL or ,300 cells/μL), protocol specified visit, region (Europe or North America) and treatment*visit interaction as fixed effects and baseline total asthma score as a covariate.. Changes at Week 12 were calculated based on patients with both baseline and Week 12. ...
Based on the modified GINA criteria, of the 397 children in the sample, 143 (36%) had intermittent asthma; 160 (40%) had mild persistent asthma; 51 (12.8%) had moderate persistent asthma; and 43 (10.8%) had severe persistent asthma. In 60 children, occasional limitation of daily activities was the indicator of greatest severity. Taking into account that responses to the remaining questions were not related to more severe asthma, a decision for more conservative categorization was made, and these children were classified as having mild persistent asthma. Based on the ISAAC questionnaire, 90 of the 397 children (22.3%) provided positive responses to questions assessing symptom severity, whereas 307 (77.3%) replied in the negative.. Comparison of both asthma severity criteria according to data from the second survey (Table 2) shows that, the greater the severity of the disease according to GINA criteria, the greater the proportion of children with more severe symptoms as assessed by ISAAC. No ...
Lung function test: Lung function test is an asthma test used to determine if there is any progress in your breathing following the inhalation of a bronchodilator. If there is fifteen percent improvement, then asthma is a possible diagnosis.. Spirometry: Spirometry is the lung function test that can be carried at asthma clinic. It is used to measure how much and how quickly you can move air out of your lungs. You have to inhale and exhale deeply and seal your lips around the mouthpiece and blow forcefully as long as possible. The information is collected by the spirometer and can be printed out on a chart called spirogram.. Skin prick test: Skin prick test is an asthma test used to identify any allergens which you may be sensitive and which may trigger asthma attack. Some small amounts of allergens are injected into your skin of the forearm and the area is monitored for a reaction.. After monitoring for fifteen minutes, if there is no visible swelling, then it may that you dont have asthma or ...
Asthma Action Plan. You and your doctor write an Asthma Action Plan together. It is a written plan that will help you stay away from triggers and take medicine to control your asthma symptoms. Learn more about an Asthma Action Plan. Always keep a copy with you.. Asthma Control Test:. The Asthma Control Test (ACT) has questions for a person with asthma. Take the ACT and see if your asthma is under control. Share the results with your doctor. Page Updated: 12/7/2017 ...
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Little is known about asthma in the elderly as most studies of this condition have not included this patient group. It is unclear whether leukotriene antagonists benefit older asthmatics. We studied the effect of adding montelukast to the asthma treatment of elderly subjects. Twenty-five subjects 65 years old and older with asthma were evaluated at week 0, 1, 5, 9, 13, and 17. Each subject received montelukast 10 mg and placebo each for 8 weeks in a cross-over design. Montelukast for 4 or 8 weeks did not significantly affect ACT, daily symptom scores, number of puffs of albuterol, spirometric values, peripheral blood eosinophils, or serum IgE vs. baseline or placebo. Similar results were obtained when analyzing subgroups of patients with lower ACT, lower FEV1, and higher eosinophils. In this study of elderly asthmatics, montelukast had no effect on asthma symptoms, number of puffs of albuterol, spirometric values, peripheral blood eosinophils or serum IgE. These results will require confirmation in
Jason Lang, MD, MPH. Summary. BACKGROUND: Poorly controlled asthma especially in children remains a major public health problem. Many children with poor asthma control experience gastroesophageal reflux (GERD). The effect of mild GERD on asthma remains controversial despite studies involving proton-pump inhibitors (PPIs) assessing their effect on asthma.. GAP: Past inconsistent findings regarding the effect of PPIs on asthma control may have resulted from ineffective dosing strategies of proton-pump inhibitors employed in these studies. Drug levels and efficacy vary widely in the population and depend on genetics. Dosing in children which adjusts for the gene CYP2C19 may improve efficacy and reduce side-effects leading to improved asthma control.. HYPOTHESES:. #1: Our group hypothesizes that genotype-tailored lansoprazole dosing will reduce asthma symptoms in children with mild symptoms of GERD compared to placebo.. #2: CYP2C19 and ABCB1 genetic variants influence the pharmacokinetics (drug ...
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Rationale. Managing chronic paediatric asthma includes optimizing both asthma control and asthma-specific quality of life (QoL). However, it is unknown to what extent asthma-specific QoL is related to asthma control or other clinical asthma characteristics over time.. Objectives. To determine in children, longitudinally:. 1) the association between asthma control and disease specific QoL;. 2) the relationship between clinical asthma characteristics and disease specific QoL.. Methods. A prospective cohort study in 96 asthmatic children was carried out over one year. During two monthly regular visits, disease specific QoL, asthma control, dynamic lung function indices, fractional exhaled nitric oxide, occurrence of exacerbations, and use of rescue medication were assessed. Association between asthma clinical characteristics and asthma-specific QoL was analysed using linear mixed models.. Results. Asthma control improvement was associated with an increase in the PAQLQ total score (p-value ...
Using the candidate gene approach (discussed earlier in this chapter), many genes have been associated with asthma or asthma-related traits such as allergy and high concentrations of immunoglobulin E (IgE) in serum (table 2). Not all of these suspected asthma susceptibility genes have been replicated in multiple independent studies. One group of (allergic) asthma susceptibility genes is involved in innate immunity responses, encompassing pattern-recognition receptors, immunoregulatory cytokines and molecules involved in antigen presentation. A second group of asthma susceptibility genes are key players in T-helper type 2 (Th2)-cell differentiation and Th2- cell effector function. Th2 cells are T-lymphocytes that drive the production of allergic immunoglobulins (IgE) and the chronic airway inflammation in (allergic) asthma.. Linkage studies in families have discovered several novel asthma susceptibility genes that are expressed in epithelial cells and/or smooth muscle cells in the airways (table ...
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Why are asthma cases growing at a rapid rate? Here are 7 key reasons, plus tips for respiratory therapists to help patients control their asthma triggers.
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About Severe Asthma. Asthma affects 315 million individuals worldwide, and up to 10% of asthma patients have severe asthma which may be uncontrolled despite high doses of standard-of-care asthma controller medicines and can require the use of chronic OCS.. Severe, uncontrolled asthma is debilitating and potentially fatal with patients experiencing frequent exacerbations and significant limitations on lung function and quality of life. Severe, uncontrolled asthma has higher risk of mortality than severe asthma.. Severe, uncontrolled asthma can lead to a dependence on OCS, with systemic steroid exposure potentially leading to serious short- and long-term adverse effects, including weight gain, diabetes, osteoporosis, glaucoma, anxiety, depression, cardiovascular disease and immunosuppression. There is also a significant physical and socio-economic burden of severe, uncontrolled asthma with these patients accounting for 50% of asthma-related costs.. About Fasenra (benralizumab). Fasenra is a ...
The Global Initiative for Asthma (GINA) today is launching a new program to recognize individuals who are helping to improve asthma awareness, diagnosis, and care in countries around the world.. The GINA Ambassador program will highlight individuals who are involved in taking care of asthma patients in the clinic, improving public policy around asthma care, implementing GINA management strategies in their local community, developing asthma education materials, building multidisciplinary asthma care teams, and organizing World Asthma Day activities.. World Asthma Day is an annual awareness - raising event held today, the first Tuesday in May, and organized by GINA. The GINA Ambassador program is being launched on World Asthma Day because it reflects the events positive theme, "You Can Control Your Asthma.". "GINAs development of an evidence - based asthma management strategy is only one step in improving asthma care around the world," says Dr. Mark FitzGerald, Professor at the University of ...
Asthma is caused by inflammation of the airways. These are the small tubes, called bronchi, which carry air in and out of the lungs. If you have asthma, the bronchi will be inflamed and more sensitive than normal.. Please make it clear to reception staff that you are asthmatic when you phone.. Our practice nurses have specialist asthma qualifications. They run clinics in order that asthma may be assessed, advice offered, queries answered and the correct treatment ensured.. Patients on asthma medication should be seen at least once a year in the asthma clinic for a check up with the nurse.. The following factsheets, available from Patient UK give information and advice on a variety of asthma related topics:. What is asthma; who does it affect?. Management of Adult Asthma. Management of Childhood Asthma. Medicines inside inhalers; types of inhaler devices. Peak Flow Meter. For more information please visit the websites below:. External Websites:. NHS Choices - Asthmas symptoms, causes, diagnosis, ...
There is no cure for Asthma; however asthma doesnt have to place significant limitations on your life. With effective treatments and management, symptoms can be controlled, minimizing their impact. Each case of asthma is different and requires treatments to be personalized. One general rule that applies to all is removing environmental factors that worsen ones asthma. Along with removing environmental factors, asthma medications are available to help control symptoms. Asthma medications are divided into two types, quick-relief and long-term and are either inhaled or in pill form. Quick-relief medicines are used to relieve coughing, wheezing and chest tightness that occurs during an asthma episode; long-term medications help control your asthma and are generally used when symptoms happen more than twice a week. For people with asthma, it is important to have an asthma management plan. An asthma management plan is created by you and your doctor. An effective plan should include; identifying and ...
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Methods All persons born in the first week of March in Britain in 1958 were recruited into the cohort. By age 42 9890 cohort members had provided a full occupational history and health information. Job titles and descriptions were initially coded into Standard Occupational Classification 1990 (SOC-90) using a text based computer program. Blind to asthma status we have recoded these jobs into the International Standard Classification of Occupations 1988 (ISCO-88) codes. The prevalence of ever working in jobs defined by these codes was determined. Adult onset asthma was defined as reporting ever asthma at ages 33 or 42 and excluding all those who reporting ever asthma at ages 11 or 16 (childhood asthma). The risk of adult onset asthma associated with these job categories was determined in logistic regression analysis adjusted for sex, smoking, region and fathers social class at birth. The Simes procedure was used to correct for multiple testing. ...
Subjects were recruited prenatally and followed prospectively, attending follow-up at ages 3, 5, 8, and 11 years. A validated questionnaire was interviewer-administered to collect information on parentally-reported symptoms (n=1051). At each follow-up, current rhinitis was defined as sneezing, runny or blocked nose in the absence of cold or flu within the last 12 months, and asthma as a positive response to at least two of the following: 1) current wheeze; 2) physician-diagnosed asthma; 3) use of asthma medication. We measured specific airway resistance (sRaw) using plethysmography (ages 5-11 years) and FEV1 by spirometry (5, 8 and 11). Information on prescribed medication and severe asthma exacerbations (ATS definition) was extracted from participants medical records. The effect of rhinitis on asthma exacerbations and lung function was investigated using longitudinal analyses. ...
Asthma is a chronic lung disease caused by airway inflammation. Asthma is the most common pediatric chronic disease [1, 2] affecting 7.1 million (9.6 %) of American children [3, 4]. Asthma is the primary diagnosis for 1/3 of pediatric emergency department visits [5], and the most frequent reason for preventable pediatric hospitalization [6] and school absenteeism due to chronic conditions [7]. In 2008, 9.3 billion dollars, or 8 % of the total direct healthcare cost for all children, were spent on pediatric asthma [1].. About 80 % of pediatric asthma patients have symptom onset before age six [8, 9], most of them before age three [10-12]. However, only about 1/3 of children with at least one episode of asthmatic symptoms by age three will have asthma at age six and over [10, 13-18]. Asthma is under-diagnosed in 18-75 % of asthmatic children [19-23]. Overdiagnosis of asthma is also prevalent. Eleven percent of patients in primary care using inhaled corticosteroids, the most potent and consistently ...
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Each patient with asthma may respond to different medications in different ways than other patients. For that reason, your doctor will pick the medication that they thinks is the best to control your asthma symptoms.. What Triggers Asthma?. Common triggers of asthma symptoms include viral upper respiratory illnesses or colds. For many patients, vigorous activity and exercise can make asthma symptoms worse. Tobacco smoke exposure, pet dander, and environmental allergen exposure (dust mites and pollens of trees, grasses and or weeds) can also make asthma symptoms worse. For some patients changes in the weather and food allergies can also make asthma symptoms worse.. How can I improve my Asthma?. • Avoiding triggers such as tobacco smoke, pet dander and environmental allergens can help maintain good control of your asthma symptoms. If you have questions about the best ways to avoid your environmental triggers, speak with your doctor or nurse ...
Objectives: The aim of this study was examined the effects of asthma on health-related quality of life (HRQoL) and compared it with HRQoL in the general Korean population using the results of a cross-sectional, nationwide survey.. Methods: Data were obtained from 229,131 participants (5,989 with asthma and 223,142 without asthma) in the 2010 Korean Community Health Survey. We compared EuroQol (EQ)-5D and EQ-visual analogue scale (VAS) scores after adjusting for sociodemographic and psychosocial factors as well as for comorbidities. Logistic regressions were used to explore determinants for the lowest quartile HRQoL in the asthma group.. Results: The mean EQ-5D and EQ-VAS scores were significantly lower in the asthma group (EQ-5D. 0.82; EQ-VAS, 64.2) than in the non-asthma group (EQ-5D, 0.90; EQ-VAS, 73.2) (P,0.001). The multivariate odd ratios (OR) for the lowest quartile of EQ-VAS in the asthma group versus the non-asthma group was 1.17 (95% CI, 1.04-1.32) and OR for the lowest quartile of ...
TY - JOUR. T1 - Evidence for asthma susceptibility genes on chromosome 11 in an African-American population. AU - Huang, Shau Ku. AU - Mathias, Rasika A.. AU - Ehrlich, Eva. AU - Plunkett, Beverly. AU - Liu, Xin. AU - Cutting, Garry R.. AU - Wang, Xin Jing. AU - Li, Xiao Dong. AU - Togias, Alkis. AU - Barnes, Kathleen C.. AU - Malveaux, Floyd. AU - Rich, Stephen. AU - Mellen, Beverly. AU - Lange, Ethan. AU - Beaty, Terri H.. PY - 2003/7/1. Y1 - 2003/7/1. N2 - Initial genome-wide scan data provided suggestive evidence for linkage of the asthma phenotype in African-American (AA), but not Caucasian, families to chromosome 11q markers (peak at D11S1985; LOD=2). To refine this region, mapping analysis of 91 AA families (51 multiplex families and 40 asthmatic case-parent trios) was performed with an additional 17 markers flanking the initial peak linkage marker. Multipoint analyses of the 51 multiplex families yielded significant evidence of linkage with a peak non-parametric linkage score of 4.38 at ...
Hypothesis and Objectives: The state of chronic Inflammation associated with asthma may contribute to the development of cardiovascular disease (CVD) in adulthood. This study evaluated prospectively the association between history of asthma and CVD in a cohort of postmenopausal women.. Methods: Study participants are postmenopausal women (n= 90,168) who are free of cardiovascular disease at baseline, evaluated from 1993-1998. We used self-report of physician diagnosed asthma to define the exposure. Information on treatment for asthma in addition to CVD risk factors were collected. The association between asthma and the incidence of CVD and coronary heart disease (CHD) was evaluated using cox proportional hazards models.. Results: Among 90,168 women in the study sample, 6,921 (7.68%) reported asthma at baseline. Baseline characteristics were similar between the asthma and no asthma groups although asthmatics were more obese (36% vs 27%; p,0.0001) and had higher hypertension rates (38% vs 31%; ...
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But unlike other kinds of asthma, allergic asthma is the result of an allergic reaction. A person who has allergic asthma develops symptoms after breathing in an allergen, such as pollen, mold spores or animal dander. The allergen causes passages in the airways of the lungs to become inflamed and swollen. This leads to an asthma attack.. In contrast, nonallergic asthma attacks are often triggered by irritants such as exercise, cold or dry air, respiratory infections, cigarette smoke, stress or anxiety.. Getting help. If you suspect you have allergic asthma, see your doctor. Your doctor may ask you to keep a log of when your asthma symptoms flare up. Or your doctor may even suggest allergy testing.. If you do have allergic asthma, its important to get the disease under control. Thats because without proper treatment, asthma can be potentially life-threatening.. If the asthma is very mild, your only treatment may be trying to avoid whatever triggers your allergy.. But chances are youll also be ...
Brittle asthma is a type of asthma distinguishable from other forms by recurrent, severe attacks. There are two subtypes divided by symptoms: Type 1 and Type 2, depending on the stability of the patients maximum speed of expiration, or peak expiratory flow rate (PEFR). Type 1 is characterized by sustained, chronic variability of PEFR, while type 2 is distinguished by sudden unpredictable drops in PEFR where asthma symptoms are otherwise well controlled and the function of the lungs is not substantially impaired. Brittle asthma is one of the "unstable" subtypes of "difficult asthma", a term used to characterize the less than 5% of asthma cases that do not respond to maximal inhaled treatment, including high doses of corticosteroids combined with additional therapies such as long-acting beta-2 agonists. The 2005 Oxford Textbook of Medicine distinguishes type 1 brittle asthma by "persistent daily chaotic variability in peak flow (usually greater than 40 per cent diurnal variation in PEFR more than ...
The results of these analyses indicate that eliminating exposures to indoor allergens and pets, if they are indeed causal, could prevent over 2 million (44.4%) of the 4.6 million cases of doctor-diagnosed asthma among persons 6 to 16 years old in the United States. The effect of eliminating these risk factors would, therefore, have a profound impact on hospitalization rates, emergency and clinic visits, costs, school absences, and health and functioning of children and adolescents.28. Having a household pet or an allergy to a pet (defined as "given up or avoided a pet because of allergies") were major risk factors for doctor-diagnosed asthma. Pet allergens are risk factors for asthma.4,,10,2029-32 Consistent with our earlier report and surveys conducted in Europe and the United States, this present analysis indicates that exposure or allergic reactions to pets were the predominant risk factor for asthma among children and adolescents.20,29-31 These variables may overestimate the risk of asthma ...
TY - JOUR. T1 - Integrating evidence for managing asthma in patients who smoke. AU - Price, David. AU - Bjermer, Leif. AU - Popov, Todor A. AU - Chisholm, Alison. PY - 2014/3. Y1 - 2014/3. N2 - Cigarette smoking among asthma patients is associated with worsening symptoms and accelerated decline in lung function. Smoking asthma is also characterized by increased levels of neutrophils and macrophages, and greater small airway remodeling, resulting in increased airflow obstruction and impaired response to corticosteroid therapy. As a result, smokers are typically excluded from asthma randomized controlled trials (RCTs). The strict inclusion/exclusion criteria used by asthma RCTs limits the extent to which their findings can be extrapolated to the routine care asthma population and to reflect the likely effectiveness of therapies in subgroups of particular clinical interest, such as smoking asthmatics. The inclusion of smokers in observational asthma studies and pragmatic trials in asthma provides a ...
TY - JOUR. T1 - Asthma and pregnancy. AU - Vatti, Rani Reddy. AU - Teuber, Suzanne S. PY - 2012/8. Y1 - 2012/8. N2 - Asthma is probably the most common serious medical disorder that may complicate pregnancy. A third of pregnant women with asthma will experience worsening of their symptoms, a third will see improvement of their symptoms and a third will see no change. The primary goal is to maintain optimal control of asthma for maternal health and well-being as well as fetal maturation. Vital patient education should cover the use of controller medication, avoidance of asthma triggers and early treatment of asthma exacerbations. Proper asthma management should ideally be started in the preconception period. Since smoking is probably the most modifiable risk factor of asthma, pregnant woman should avoid active and passive smoking. Acute asthma exacerbation during the first trimester is associated with an increased risk of congenital malformations. Poorly controlled asthma is associated with low ...
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Human translational asthma research is supported by the Parkes Family foundation, as well as individual Division investigators. The Parkes family founded the Mary Parkes Asthma Center, which became affiliated with the Pulmonary Division in 1995. We started a Severe Asthma Clinic in 2007 with the goal of providing expert evidenced-based care using non-invasive biomarkers to guide therapy and accelerate research. The Severe Asthma Clinic is staffed by Drs. Michael Larj, Sandhya Khurana, and the Mary Parkes Asthma Research Fellow.. A major theme of basic asthma research is to define the cellular and molecular mechanisms for dysregulated immune responses in asthma. Specific areas of interest include: (i) activation of lung dendritic cells by ambient air pollution and allergen particles, (ii) the role of transcription factors in T cell activation and allergic immune responses, and (iii) molecular mechanisms regulating oxidative stress. Laboratory-based investigators include Dr. Steve Georas, Dr. Jia ...
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Evidence suggests that the global prevalence of asthma is increasing by as much as 50% every 10-15 years.1 Usually, asthma can be controlled so that an individual experiences minimal symptoms (cough, wheeze, shortness of breath) and few disruptions in usual daily activities. As a result, the goal of asthma care guidelines internationally is to achieve minimal experience of symptoms and disruption because of asthma while using the least amount of medication.1-,4 Typically, core elements of asthma practice guidelines include confirming the diagnosis, providing appropriate medications, using environmental control strategies to minimise or avoid exposure to triggers, and providing asthma education and support for self management.1-,4. Previous work by Gibson et al established that adults with asthma who receive self management education, RMR, and a written action plan show important improvements in asthma outcomes, such as use of healthcare services (emergency department visits and unscheduled ...
BACKGROUND: The burden of asthma and rhinitis on health-related quality of life (HRQL) among adults has been assessed mainly in studies of patients seeking health-care, while population-based studies are relatively scarce. The objective of this study was to investigate HRQL among subjects with asthma and rhinitis derived from a random population sample and to identify factors related to impairment of HRQL.. METHODS: A randomly selected cohort was invited to participate in a postal questionnaire survey. Of those who responded, a stratified sample of 1016 subjects was invited to clinical examinations and interviews, and 737 subjects in ages 21-86 years participated. Of these, 646 completed HRQL questions. HRQL was assessed with the generic SF-36 Health Survey.. RESULTS: The physical score was lower among subjects with asthma vs. subjects without asthma (p , 0.001). No significant difference was found in the mental score. Subjects with well-controlled asthma had higher physical score compared to ...
Examination Review Course - 13 Participants; 6 new certified asthma educators!. Physician Asthma Care Education (P.A.C.E.) - A total of 30 physicians, 7 nurse practitioners, 4 nurses, and 4 other health care providers attended Asthma Care Coordinator at The Brooklyn Hospital Center - Provide asthma education and care coordination to patients and families: 153 Patients Brooklyn Community Asthma Needs Assessment - Surveyed 279 community members to determine their asthma knowledge and how they wanted to learn about asthma Partnerships Established. New York Department of Health and Mental Hygiene (NYCDOHMH)- Asthma Initiative-Asthma Training Institute ...
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Check your spirometry predicted values, record peak flow results in our chart. The Global Asthma Report 2011 http://www.globalasthmareport.org. Asthma affects 235 million people today and prevalence is rising. Low- and middle-income countries suffer the most severe cases.. We have the tools to counter the devastating personal and economic impact of untreated and poorly managed asthma.. The British Asthma Guideline recommends the Royal College of Physicians three questions to assess asthma control over the preceding month.. Have you had any difficulty sleeping because of asthma symptoms, have you had your usual asthma symptoms during the day, and has your asthma interfered with your usual activities?. A personal asthma action plan is a tailored written record of what action to take when symptoms or peak flow readings deteriorate. It includes information about when the patient needs to seek medical help or emergency care. This encourages the patient to take more responsibility for their asthma ...
As a long-term advocate for children with asthma and their families, Visionary Consulting Partners, LLC (Visionary) anticipates the release of new national guidelines for the diagnosis, treatment, and management of asthma in August of 2019. The most recent iteration of guidelines was published in 2007 by the National Asthma Education and Prevention Program (NAEPP) Committee, coordinated by the National Heart, Lung, and Blood Institute (NHLBI). The 2007 National Asthma Education and Prevention Program Guidelines for the Diagnosis and Management of Asthma provided an evidence-based foundation for physicians, respiratory therapists, pharmacists, researchers, and educators to diagnose, treat, and manage asthma in patients. In 2014, an Asthma Expert Working Group was convened by the NHLBI with the goal of determining the need and scope of an update to these guidelines. Currently, the group is working to identify critical findings across systematic reviews, meta-analyses, and clinical trials to inform ...
The National Asthma Council Australia has issued a warning to Australians living with asthma, urging them to protect their health and to be prepared as the cold and flu season kicks in.. According to the Council, around 40,000 Australians are hospitalised and 400 die from asthma each year, with winter being a particularly difficult season for asthmatics.. National Asthma Council Australia Chair, Dr Jonathan Burdon AM issued the warning today, urging the estimated 2.5 million Australians living with asthma to be pro-active in their approach to protecting their health this winter.. "During winter, respiratory tract infections typically increase. Those with asthma need to take positive steps to manage their asthma, and help prevent a flare-up turning into something more serious.. "The common cold is behind four out of five bad asthma flare-ups or attacks in winter. If you have asthma, you should see your doctor for an asthma check-up before the cold and flu season sets in to make sure your asthma ...
TY - JOUR. T1 - A study of propensity for development of bronchial asthma in preadolescents with family history of asthma by spirometry and body mass index. AU - Bhattacharyya, S.. AU - Panchami, R.. AU - Ganaraja, B.. AU - Bhat Ramesh, M.. PY - 2012/1/1. Y1 - 2012/1/1. N2 - Hereditary occurrence of Bronchial asthma has been long been postulated and several studies gave useful information in support of this. Therefore family history of hypersensitivity and asthma is an important factor in the prediction, diagnosis, prevention and/or treatment of Asthma. We studied the young school children (10-11 years; n=150 in groups of 50 each) without any history of Bronchial asthma and those with history of bronchial asthma and those having parents with asthma, in three separate groups. The parameters studied were Forced Vital capacity (FVC), FEV1 (Timed vital capacity), FEV1/FVC Ratio, Peak Expiratory Flow Rate measurements and Correlated with BMI. Comparison of the parameters by ANOVA revealed that there ...
Background: While patients personality has been thought to affect all_ergic diseases, the association of asthma and psychological factors is still debated. Stress is believed to predispose to asthma, but no clear evidence of causality has been found. We have studied the role of psychological factors in prevalent as well as in incident asthma cases among the adult population.. Methods: A total of 11540 adults initiall_y aged 18-45 years responded to three questionnaires in 1975, 1981, and 1990, respectively. The association of psychological factors (including extroversion and neuroticism scales, subjective stress, and life satisfaction) and prevalent asthma was studied, as well as the predisposing effect of these factors on the risk of adult onset asthma. Logistic regression was used for risk calculations.. Results: Low life satisfaction was associated with asthma prevalence (age- and sex-adjusted OR=2.27: 1.04-4.93 for prevalent asthma among those with low life satisfaction compared to those ...
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Based on your history and asthma severity, you and your doctor will develop a care plan called an "asthma action plan." The asthma action plan describes when and how to use your medicines, actions to take when asthma worsens, and when to seek emergency care. Make sure you understand this plan. If you do not, ask your asthma care provider any questions you may have.. Your asthma action plan is one of the keys to controlling asthma. Keep it readily available to remind you of what you need to do every day to control asthma and what you need to do when symptoms occur.. ...
Aim 1. To investigate the relation of the airway microbiome to risk of childhood asthma among infants with severe bronchiolitis (MARC-35). Aim 2. To investigate the relation of longitudinal patterns of the airway microbiome (e.g., infancy, age 3y, and age 6y) to the risk of childhood asthma in the MARC-35 and MARC-43 cohorts combined. MARC-43 is a separate cohort of children enrolled as healthy infants; it is funded by UG3OD023253 and covered by a separate IRB application at sites involved. Aim 3. To identify nasal airway microRNAs that are prospectively associated with asthma at age 6 years. Aim 4. To compare asthma cases vs non-cases on downstream NFκB signaling mediators and outcomes associated with nasal airway microRNAs. Aim 5. To derive asthma endotypes at age 6 years. By integrating microRNA expression, NFκB signaling mediators and outcomes, and asthma phenotyping data from the age 6-year examination, we will determine asthma endotypes with the use of an innovative systems-based
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We propose to study endotoxin-induced airway conditions in children through three complementary clinical investigations. First, we will capitalize on an ancillary study of a NIH-sponsored multi-center cohort of children with asthma (Childhood Asthma Management Program), which has tracked asthma severity for over a decade, to determine if endotoxin exposure, modified by genetics and environment, is associated with greater disease severity and persistence. Second, we propose a panel study of children with asthma to investigate whether endotoxin exposure, modified by environment, is associated with inflamed airways and elevated TLR expression on airway macrophages. Clinically, these inflammatory responses could drive poor asthma control and exacerbations. Finally, we will take advantage of a HUD-sponsored inner-city home intervention study to determine if a home environment intervention will reduce home endotoxin levels and improve asthma. ...
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Does your child have asthma? We are looking for children ages 4 to 11, who have been diagnosed with asthma for at least 3 months to participate in an ASTHMA study. Compensation for time and travel is provided. Please contact our office for more information and to schedule your appointment. We are happy to answer any questions. Call 915-544-2557 today!!!. Help and Be Helped!. ...
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Asthma is more common than ever, so more people require treatment. This need has produced a variety of different asthma treatments. Now you can find something to help with your asthma. There is no better way to find the help you can use than to check out the information in this article.. If you suffer from asthma, you should not smoke or expose yourself to any type of vapors or fumes. Stay far away from any tobacco products. You should also consider where you work, as factories may expose you to harmful vapors or smoke.. Do you know the type of asthma that you suffer with? Knowing as much as possible about your specific type of asthma will go an incredibly long way in helping you combat the day-to-day effects it has on you. People suffering from asthma that is exercise-induced, for example, had best be prepared for asthma attacks at the gym! Knowing your asthma symptom patterns will help keep you safe.. To keep your child healthy, make sure they are never around smoke. Secondhand smoke can ...
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About the Author Home Remedies For Asthma - Easy And Simple 0 Any person who believes he secretions can not drain and strengthens his injury to full relocation. My mom says Im obese because my asthma medicine cells, chick embryo, and ingredients similar to antifreeze, among other things. Asthma symptoms can be brought on by dozens of different things, and into the esophagus and back down into the lungs causing irritation. Ive read that the more asthma attacks you , has also proven successful in preventing asthmatic attacks in some persons.. People with breathing problems that can breath steamy air often report up within the middle of the night with terribly strong n sharp. Van Helmont, the famous physician who suffered from asthma was the is you can apply for asthma grants especially if you are suffering from chronic asthma problem. With good performance patients on doctors advice can reduce is significantly abnormal chart and i definately have asthma. These exercises are not only a ...
Causes and natural remedies for Asthma, including dietary changes, supplements and a comprehensive Wellness Program - Asthma, Asthma Treatment, Breathing Problems, Asthma Products, Asthma Inhaler, Bronchial Asthma, Asthma Symptoms, Wheezing, Allergies
The main difference between cat allergies and asthma is the fact that the allergies are a response of the immune system. Asthma is a condition that occurs in the airways and the lungs. Allergies are more frequent in felines, while the percentage of cats affected by asthma is less than 1%. However, some cats that have asthma may easily develop allergies as well. Conversely, if the cat has allergies and is exposed to the allergen, may develop chronic asthma. The symptoms of asthma are similar to the symptoms of allergies: the air passages will get swollen and irritated both in asthma and in the case of allergies; however, in allergies, the cat may also experience additional symptoms such as skin itchiness, dermatitis or nasal and ocular discharges; these symptoms will not be present in a cat that is affected by asthma. Another connection between cat asthma and allergies is the fact that certain allergens may cause an asthma attack. ...
A peak flow meter for asthma is a handheld meter that measures how well air flows out of the lungs. Measuring your peak flow using this device is an important part of managing your asthma symptoms and preventing an asthma attack. That is because sometimes you may feel your breathing is fine, but when you measure it with a peak flow meter, you find your lung function is slightly decreased. A PFM can be used to:. • Determine the severity of your asthma. • Check your response to treatment during an acute asthma episode. • Monitor progress in treatment of chronic asthma and provide information for any changes in your therapy. • Detect worsening lung function and avoid a possible serious asthma flare-up. A peak flow meter can help you and your allergist evaluate how severe your asthma is at any point in time. With a peak flow meter, you can often see a drop in your readings even before your symptoms (like coughing or wheezing) get worse. Decreases in peak flow may show that you need to ...
TY - JOUR. T1 - Validation of a standardized version of the asthma quality of life questionnaire. AU - Juniper, Elizabeth F.. AU - Buist, A (Sonia). AU - Cox, Fred M.. AU - Ferrie, Penelope J.. AU - King, Derek R.. PY - 1999. Y1 - 1999. N2 - Background: In the original 32-item Asthma Quality of Life Questionnaire (AQLQ), five activity questions are selected by patients themselves. However, for long-term studies and large clinical trials, generic activities may be more appropriate. Methods: For the standardized version of the AQLQ, the AQLQ(S), we formulated five generic activities (strenuous exercise, moderate exercise, work-related activities, social activities, and sleep) to replace the five patient-specific activities in the AQLQ. In a 9-week observational study, we compared the AQLQ with the AQLQ(S) and examined their measurement properties. Forty symptomatic adult asthma patients completed the AQLQ(S), the AQLQ, the Medical Outcomes Survey Short Form 36, the Asthma Control Questionnaire, ...
My daughter has asthma and is also allergic to tree nuts. I have been told that because she has asthma we should be extra careful in preventing her from eating tree nuts. Of course we are always reading labels and protecting her from accidentally eating nuts but what does having asthma have to do with the food allergy?. The major concern is in patients who have poorly controlled asthma since a reaction to a food allergy could more easily lead to a severe asthma exacerbation along with any other allergic symptoms such as hives. Although controlled asthma in that circumstance could certainly be worsened, even become severe, it is little less likely to do so. This is one among many reasons why parents of children with asthma need to seek to reach the best possible control of their childrens asthma so they are less vulnerable to sudden episodes of worsening when exposed to asthma triggers, be it food, pollen, animal allergens or respiratory infections ...
A peak flow meter could actually save your life and ward off an asthma attack by allowing you to respond quickly to asthma flare-ups such as coughing, wheezing, and mucus production. These devices were created to help you manage your asthma, especially during physical activity. Peak flow meters measure daily variations in your breathing letting you know that your body has reached its limit by the number indicated on the meter. If the number is lower than your optimal amount, you should stop and rest, and/or take medication, depending on your doctors orders. Your doctor will also be able to tell whether your asthma medication is working based on the readings of the meter. Many people take daily asthma medication along with using their peak flow meter on a daily basis. Peak flow meters are hand-held and portable, and give you the confidence of being able to monitor your asthma symptoms before they start. The higher the number, the healthier you are, so you know that your asthma management plan is ...
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At-risk patients to target for special review. · Children with frequent consultations for respiratory infections. · Children over 5 years old with persistent asthma symptoms. · Asthma patients with psychiatric disease or learning disabilities. · Patients using large quantities of ?-2 agonists. Monitor asthma control through regular checks on the proportion of patients with asthma:. lwho have no or few current symptoms. lwho are able to use their prescribed inhalers effectively. lwho use inhaled steroids. lwith normal lung function (PEF greater than 80 per cent). lwith actual/best PEF greater than 85 per cent. lwith an asthma action plan. Organisation of care. Practices should use a structured record including inhaler technique, morbidity, PEF, current treatment and action plans Source: Thorax (February) ...
NOGUEIRA, Katia T.; LOPES, Claudia S. and FAERSTEIN, Eduardo. Self-reported history of physician-diagnosed asthma and common mental disorders among civil servants at a public university in Rio de Janeiro, Brazil: the Pró-Saúde study. Cad. Saúde Pública [online]. 2007, vol.23, n.7, pp.1633-1639. ISSN 0102-311X. https://doi.org/10.1590/S0102-311X2007000700014.. This study investigates the association between history of asthma and common mental disorders among employees at a public university in the State of Rio de Janeiro, Brazil. Phase 1 cross-sectional data from a cohort study (the Pró-Saúde Study) were collected from 4,030 employees. Asthma was ascertained by self-reported medical diagnosis, and the occurrence of common mental disorders was based on the General Health Questionnaire (GHQ-12). Generalized linear models were used to calculate prevalence rates. Asthma prevalence was 11% (444), of whom 39.7% (176) presented common mental disorders. History of asthma was associated with higher ...
Introduction: Approximately 7.1 million US children have asthma. The burden of asthma is disproportionate with ruralUSpopulations experiencing a higher prevalence of the disease. Rural populations experience additional disparities regarding health care access, job availability, and daily living resources. Hence, the family impact of having a child with asthma may be influenced by geographic locale. This impact could be a result of health insurance tied to employment, out of pocket costs, and health care provider availability. Few studies have assessed the impact a childs asthma has on a family. This study sought to answer the question: What is the impact of children with asthma on US rural families? Methods: Multivariate techniques were performed to examine a single year of data from two connected population-based datasets, the 2007-2008 National Survey of Childrens Health and the 2009-2010 Children with Special Health Care Needs Survey. Children with current asthma defined the study
BRONCHIAL ASTHMA IN MEDICALITERATURL E OF GREEK ANTIQUITY. the chapter on the treatment of asthma of the Aretaeus work has not been preserved.It is important to recognize that the debate so that painful sexual problems buy seroquel online no prescription is not. to get prednisone. not work to.. Sports Respiratory Clinic. It is possible respiratory symptoms experienced during exercise are not related to asthma;. posture work and inspiratory muscle.The Global Asthma Report 2014 has been prepared by the. No one else is currently doing this work. GAN aims to reduce asthma suffering by improving asthma.Influenza vaccination of children during acute asthma exacerbation and concurrent prednisone therapy. rash, and headache, were not different in the two groups.Asthma and apo - Craft a quick custom essay with our help and make your teachers startled Qualified scholars working in the company will fulfil your assignment within.Asthma Guidelines. Following science-based guidelines works. Not only do they ...
Asthma action plan. Review the plan. Make sure teachers know how to use an inhaler, spacer, and peak flow meter. Make sure they understand the action plan zones and what to do. Discuss any school policies that affect your childs asthma management. For instance, some schools allow kids to keep their quick-relief medicine with them in their bag or locker, but other schools keep medicines in the school office. Many states now have laws that require students be allowed to carry and take asthma medicines on their own. Discuss local policies with your healthcare provider. ...
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Ontarios Asthma Program (AP) is funded by the Ontario Ministry of Health and Long Term Care and is an evidence-based program supporting asthma best practices across a variety of health care settings and community environments, where people with asthma live, learn, work and play. The goal of the AP is to reduce asthma associated mortality, morbidity and health care costs for children and adults with asthma through integrated initiatives focused on health promotion and prevention, management and treatment, research and surveillance.
Background: It is unclear why obesity is associated with worse asthma control. We hypothesized that(1) obesity affects asthma control independent of spirometry, airway inflammation, and airway hyperresponsiveness (AHR) and (2) residual symptoms after resolution of inflammation are due to obesity-related changes in lung mechanics. Methods: Forty-nine subjects with asthma underwent the following tests, before and after 3 months of high-dose inhaled corticosteroid (ICS) treatment: five-item asthma control questionnaire (ACQ-5), spirometry, fraction of exhaled nitric oxide (FENO), methacholine challenge, and the forced oscillation technique, which allows for the calculation of respiratory system resistance (Rrs) and respiratory system reactance (Xrs) as indicators of airway caliber and elastic load, respectively. The effects of treatment were assessed by BMI group (18.5-24.9, 25-29.9, and ≥30 kg/m 2 ) using analysis of variance. Multiple regression analyses determined the independent predictors of ACQ-5
Factors that may trigger or worsen asthma symptoms include viral infections, domestic or occupational allergens (e.g., house dust mite, pollens, cockroach), tobacco smoke, exercise and stress. These responses are more likely when asthma is uncontrolled. Some drugs can induce or trigger asthma, e.g., beta-blockers, and (in some patients) aspirin or other NSAIDs.. Asthma flare-ups (also called exacerbations or attacks) may occur, even in people taking asthma treatment. When asthma is uncontrolled, or in some high-risk patients, these episodes are more frequent and more severe, and may be fatal.. A stepwise approach to treatment takes into account the effectiveness of available medications, their safety, and their cost to the payer or patient.. Regular controller treatment, particularly with inhaled corticosteroid (ICS)-containing medications, markedly reduces the frequency and severity of asthma symptoms and the risk of having a flare-up.. Asthma is a common condition, affecting all levels of ...
Asthma[edit]. Epinephrine is also used as a bronchodilator for asthma if specific β2 agonists are unavailable or ineffective.[ ... There is an epinephrine metered-dose inhaler sold over-the-counter in the United States for the relief of bronchial asthma.[47] ... When given by the subcutaneous or intramuscular routes for asthma, an appropriate dose is 0.3 to 0.5 mg.[26][27] ... The Primatene® Mist brand has built a long-time heritage for over-the-counter relief of bronchial asthma.. ...
Asthma[edit]. Main article: Asthma. The bronchi are the main passages to the right and left lungs. These airways carry the ... You can be more prone to developing this infection if you have asthma, flu, heart disease, or cancer[8][dead link] ... Inflammation of the bronchii and bronchioles can cause them to swell up, which could lead to an asthma attack. This results in ... There are different types of asthma that affect the functions of the bronchial tubes. Allergies can also set off an allergic ...
HODE replicated many of these features of asthma,[62] In the mouse model of asthma and in the human disease, epithelial cells ... Asthma[edit]. In guinea pigs, 13(S)-HODE, when injected intravenously, causes a narrowing of lung airways and, when inhaled as ... of asthma and that pharmacological inhibitors of TRPV1 may eventually proved to be useful additions to the treatment of asthma ... human suffers of asthma exhibit increased levels of 13-HODE in their blood, sputum, and washings form their lung alveola (i.e. ...
Asthma[edit]. In 2009, the national office and four of its State chapters provided training support to 49 pediatric practices ... The percentage of patients at participating practices with well-controlled asthma (as defined by the National Heart, Lung, and ... "National Academy and Affiliated State Chapters Support Pediatricians in Improving Asthma Care, Leading to Better Guideline ... to improve adherence to well-established asthma care guidelines. ...
... asthma[edit]. Main article: Thunderstorm asthma. Thunderstorm asthma is the triggering of an asthma attack by ... Taylor, P.E. & Jonsson, H. Thunderstorm asthma. Curr Allergy Asthma Rep (2004) 4: 409. doi:10.1007/s11882-004-0092-3 ... Suphioglu C. Thunderstorm Asthma Due to Grass Pollen. Int Arch Allergy Immunol 1998;116:253-260. doi:10.1159/000023953 ... Dabrera G, Murray V, Emberlin J, Ayres JG, Collier C, Clewlow Y, Sachon P. Thunderstorm asthma: an overview of the evidence ...
Asthma/COPD[edit]. It is recommended that asthmatics and COPD patients be vaccinated against flu before the flu season. People ... with asthma can develop life-threatening complications from influenza and the common cold viruses. Some of these complications ...
... asthma, rashes, and eczema; d) NSAID-induced acute non-allergic reactions such as asthma, rhinitis, conjunctivitis, angioedema ... "Annals of Allergy, Asthma & Immunology. 111 (3): 155-62. doi:10.1016/j.anai.2013.06.031. PMC 4088989. PMID 23987187.. ... Allergic asthma[edit]. The upstream promoter in the human ALOX5 gene commonly possess five GGGCCGG repeats which bind the Sp1 ... Zileuton is approved in the U.S.A. for the prophylaxis and chronic treatment of allergic asthma; it is also used to treat ...
Asthma[edit]. Infants may develop respiratory symptoms as a result of exposure to Penicillium, a fungal genus. Signs of mold- ... Studies have indicated a correlation between the probability of developing asthma and exposure to Penicillium.[6] ... Damp indoor environments correlate with upper-respiratory-tract symptoms, such as coughing and wheezing in people with asthma.[ ... "Levels of Household Mold Associated with Respiratory Symptoms in the First Year of Life in a Cohort at Risk for Asthma" ...
Asthma[edit]. Developing asthma due to abdominal obesity is also a main concern. As a result of breathing at low lung volume, ... 2003). "Body Mass Index and Asthma Severity Among Adults Presenting to the Emergency Department". Chest. 124 (3): 795-802. doi: ... A study has stated that 75% of patients treated for asthma in the emergency room were either overweight or obese.[35] ... Shore, S.; Johnston, R. (2006). "Obesity and asthma". Pharmacology & Therapeutics. 110 (1): 83-102. doi:10.1016/j.pharmthera. ...
Asthma[edit]. As of 2015, there was no evidence that taking omega−3 supplements can prevent asthma attacks in children.[68] ... atopic dermatitis and allergic asthma) are controversial; therefore, at the present stage of our knowledge (as of 2013) we ... "Omega-3 Fatty Acids Supplementation in Children to Prevent Asthma: Is It Worthy?-A Systematic Review and Meta-Analysis" ...
Asthma Management[edit]. Independent pharmacists assist patients to manage and maintain asthma control. Asthma management ... reinforcing and clarifying instructions as outlined in their asthma management plan provided by their physician; and addressing ... services include education on the types and purposes of asthma medications; demonstrating the correct techniques on using their ...
Allergy Asthma Immunol. 75 (5): 429-33. PMID 7583865.. *^ Frosch PJ, Rastogi SC, Pirker C, et al. (April 2005). "Patch testing ... Immunological; asthma and allergy[edit]. Evidence in peer-reviewed journals shows that some fragrances can cause asthmatic ... "Inhalation challenge effects of perfume scent strips in patients with asthma". Ann. ... reactions in some individuals, especially those with severe or atopic asthma.[34] Many fragrance ingredients can also cause ...
Asthma[edit]. Beta blockers are contraindicated in patients with asthma as stated in the British National Formulary 2011.[ ... Ahrens RC (1990). "Skeletal muscle tremor and the influence of adrenergic drugs". The Journal of Asthma. 27 (1): 11-20. doi: ... Beta blockers can have a constricting effect on the bronchi of the lungs, possibly worsening or causing asthma symptoms.[68] ... citation needed] The 2007 National Heart, Lung, and Blood Institute (NHLBI) asthma guidelines recommend against the use of non- ...
Chu, Eric K.; Drazen, Jeffrey M. (1 June 2005). "Asthma". American Journal of Respiratory and Critical Care Medicine. 171 (11 ... asthma, nasal congestion and as anesthetics.[24] Drugs used to treat obesity are called anorectics and generally include drugs ... orally have been used to treat asthma, but inhaled adrenergic drugs are now preferred due to less systemic side effects. ... "Epinephrin; especially in asthma". California State Journal of Medicine. 3 (2): 54-5. PMC 1650334. PMID 18733372 ...
X-linked dominant disorders are caused by mutations in genes on the X chromosome. Only a few disorders have this inheritance pattern, with a prime example being X-linked hypophosphatemic rickets. Males and females are both affected in these disorders, with males typically being more severely affected than females. Some X-linked dominant conditions, such as Rett syndrome, incontinentia pigmenti type 2, and Aicardi syndrome, are usually fatal in males either in utero or shortly after birth, and are therefore predominantly seen in females. Exceptions to this finding are extremely rare cases in which boys with Klinefelter syndrome (47,XXY) also inherit an X-linked dominant condition and exhibit symptoms more similar to those of a female in terms of disease severity. The chance of passing on an X-linked dominant disorder differs between men and women. The sons of a man with an X-linked dominant disorder will all be unaffected (since they receive their father's Y chromosome), and his daughters will ...
These modifiers have been shown to improve asthma symptoms, reduce asthma exacerbations and limit markers of inflammation such ... "A review on leukotrienes and their receptors with reference to asthma". Journal of Asthma. 50 (9): 922-931. doi:10.3109/ ... Fanta CH (March 2009). "Asthma". N Engl J Med. 360 (10): 1002-14. doi:10.1056/NEJMra0804579. PMID 19264689.. ... and mucus secretion in asthma and COPD.[1] Leukotriene receptor antagonists are sometimes colloquially referred to as leukasts ...
... asthma); and died within two years of the other (Prus in 1912; Bierce presumably in 1914). Prus, however, unlike Bierce, went ...
"Asthma Team". *Sid Roams. *DJ Revolution. 1:59. 16.. "Do What U Do (Remix)" (featuring Malice and Nickelus F). Boi-1da. 2:56. ...
Moderate-to-severe asthma not controlled by inhaled steroids. Chronic idiopathic urticaria. 504. 2012[83]. 4%. ...
Asthma attack 3. Urgent. Stable, with multiple types of resources needed to investigate or treat (such as lab tests plus X-ray ...
Asthma and Allergies: The Symptoms Archived 17 September 2010 at the Wayback Machine. Asthma & Allergies. Retrieved on 31 ... July 1969). "Allergic asthma caused by basidiospores". Lancet. 2 (7612): 131-3. doi:10.1016/s0140-6736(69)92441-6. PMID 4183245 ... Fungal allergies are associated with seasonal asthma.[19][20] They are considered to be a major source of airborne allergens.[ ... Those with asthma are more likely to have immediate allergic reactions and those with allergic rhinitis are more likely to have ...
"Allergy, Asthma & Clinical Immunology. 14 (2): 57. doi:10.1186/s13223-018-0286-1. ISSN 1710-1492. PMC 6157280. PMID 30275847.. ... Allergy Asthma Immunol. 119 (3): 214-222.e3. doi:10.1016/j.anai.2017.07.010. PMID 28890018.. ... James JM, Crespo JF (2007). "Allergic reactions to foods by inhalation". Curr Allergy Asthma Rep. 7 (3): 167-174. doi:10.1007/ ... From reviews, there appears to be a treatment benefit for eczema,[127][128][129] but not asthma, wheezing or ...
Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specific IgE Test Task Force". Ann. Allergy Asthma ... American Academy of Allergy, Asthma, and Immunology. "Five Things Physicians and Patients Should Question" (PDF). Choosing ... Currently, allergic diseases and asthma are usually treated with one or more of the following drugs: (1) antihistamines and ... Xolair has been approved in many countries for treating severe, persistent allergic asthma. It has also been approved in March ...
"Asthma Community Network". Boston Urban Asthma Coalition. Retrieved 2016-04-24.. *^ a b Friedman, Evelyn. "Real Estate Trends ... In Dorchester there is a local organization by the name of Urban Asthma Coalition. This organization aims to promote the ... with the communities to change the policies through administrative advocacy that affect the community members who have asthma. ... collaboration between other organizations and residents who are concerned about factors in the community that affect asthma. ...
Irritant, asthma risk Safety data sheet ICSC 1175 GHS pictograms GHS signal word Danger ...
Frequently asked questions about asthma, asthma attacks, and how to control asthma ... What Causes an Asthma Attack?. An asthma attack can happen when you are exposed to "asthma triggers." Your asthma triggers can ... Air pollution and viral lung infection may also lead to asthma.. Occupational asthma occurs when someone who never had asthma ... State and City Asthma Contacts and Programs. * Historical Information: Asthma at a Glance 2002-2010plus icon * 2010 At A Glance ...
CDC works to help Americans with asthma achieve better health and improved quality of life. ... State and City Asthma Contacts and Programs. * Historical Information: Asthma at a Glance 2002-2010plus icon * 2010 At A Glance ... Asthma Surveillance dataplus icon * NHIS Asthma Prevalence Dataplus icon *2018 Data ... CDCs National Asthma Control Program works to help Americans with asthma achieve better health and improved quality of life. ...
Types of Asthma. Adult-Onset Asthma. Can you get asthma as an adult? What causes adult onset asthma? Read more to find out, and ... Allergic Asthma. Learn about the triggers and treatment for allergic asthma and how an allergist can help you manage allergy ... Nonallergic Asthma. Learn about the triggers and treatment for non-allergic asthma and how an allergist can help you manage ... Asthma-COPD Overlap. How does chronic obstructive pulmonary disorder (or COPD) overlap with asthma? Learn the symptoms and ...
Allergy and Asthma Proceedings. ISSN 1088-5412 (Print); ISSN 1539-6304 (Online) Visit publication homepage ... Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding ... Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, ... with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma. ...
There is no cure for asthma, but the good news is it can be managed and treated so you can live a normal, healthy life. ... Asthma is a lung disease that makes breathing difficult for millions of Americans. ... Living with Asthma Online Support Community. Learn About Asthma. What is asthma? The more you can learn about asthma, the ... Asthma. Asthma is a lung disease that makes breathing difficult for millions of Americans. There is no cure for asthma, but the ...
State and City Asthma Contacts and Programs. * Historical Information: Asthma at a Glance 2002-2010plus icon * 2010 At A Glance ... Asthma Surveillance dataplus icon * NHIS Asthma Prevalence Dataplus icon *2018 Data ... CDCasthma on Twitter to learn more about helping people with asthma live healthier lives by gaining control over their asthma. ... You can control your asthma and avoid an attack by taking your medicine exactly as your doctor or other medical professional ...
Childrens Hospital of Wisconsins team of specialists treat children and adults with asthma, allergies and immunological ... Childrens is a leader in asthma, allergy and immune disorder research. We actively develop new solutions and research cures. ... Childrens Hospital of Wisconsin offers a truly unique approach to asthma, allergy and immunology diagnosis and care. Our board ... These include our Primary Immunodeficiency Program, Asthma Plus Program and clinical nutrition services. ...
Liquid Prednisone For Asthma. Vipps Certified Online Pharmacy. Monday Through Saturday Delivery. Browse An Extensive Online ... Rituximab is liquid prednisone for asthma given generally.. This includes guaifenesin and liquid prednisone for asthma top- ... The group of asthma the corticosteroid provided an funny scratch with lady steroid of each resort, their evening, condition, ... I am on liquid prednisone for asthma the my histologic subject at the 30 effect. While a adventitia may not provide good cat, ...
Asthma Briefs on WAO TV. Difference between Severe Asthma and Difficult-to-Control Asthma, Peter Howarth, BSc (Hons), MBBS, DM ... Severe Asthma in Developing Countries Alvaro A. Cruz, MD Watch Video. Asthma COPD Overlap Syndrome (ACOS) Maarten van den Berge ... Precision Medicine as It Relates to Severe Asthma Sally E. Wenzel, MD Watch Video. Blood Eosinophils in Severe Asthma David B. ... Severe Asthma - New Insights: Recorded WAO Symposium. Bronchial Thermoplasty: An Option for Difficult-to-Treat Severe Asthma: ...
... who suffered an asthma attacked believed to be caused by the bushfire smoke. The 19-year-old from Glen Innes, NSW, died on the ... They wish to raise awareness of the seriousness of asthma, the risks to people with asthma and the dangers of bushfire smoke, ... Our hope is that an ongoing conversation now begins about the seriousness and often unpredictable nature of asthma. Asthma can ... Asthma Australia shared the tragic news on their Facebook page, writing, Courtney lost her life in late November when bushfire ...
The Pediatric Asthma Risk Score could improve on the track record of the Asthma Predictive Index, which in the past has been ... the Pediatric Asthma Risk Score (PARS), to help predict pediatric asthma better than current standard test Asthma Predictive ... The study, "A Pediatric Asthma Risk Score to better predict asthma development in young children," was published online in The ... At age 7, asthma was diagnosed based on reported symptoms and measurement of lung function with spirometric tests according to ...
Prevention of Occupational Asthma (OA) Research. This page is no longer available and has been replaced by the following page, ...
The National Asthma Council Australia is a not-for-profit organisation working to improve health outcomes and quality of life ... The National Asthma Council Australia. We are the national authority for asthma knowledge, setting the standard for asthma care ... A new chapter for the National Asthma Council. *Latest data shows drop in asthma deaths, but Asthma Council warns against ... Asthma & allergy sensitive products. Our Sensitive Choice website. To help you identify asthma and allergy-aware products, ...
National Institute of Environmental Health Sciences: Asthmaexternal icon. *Environmental Protection Agency: Asthmaexternal icon ... Characteristics of Asthma Visits to Physician Offices in the United States: 2012-2015 National Ambulatory Medical Care Survey ... Quickstats: Percentage of All Emergency Department Visits Made by Patients with Asthma, by Sex and Age Group - National ... Number of physician office visits with asthma as a primary diagnosis: 9.8 million ...
National Asthma Control Program - National Center of Environmental Health (NCEH) - Centers for Disease Control and Prevention ( ... State and City Asthma Contacts and Programs. * Historical Information: Asthma at a Glance 2002-2010plus icon * 2010 At A Glance ... Asthma Surveillance dataplus icon * NHIS Asthma Prevalence Dataplus icon *2018 Data ... CDCasthma on Twitter to learn more about helping people with asthma live healthier lives by gaining control over their asthma. ...
Asthma Asthma and Chiropractic. Chiropractic is not a treatment for asthma. However, many who suffer from asthma report ... Asthma cases seem to be rising at an alarming rate. Some think its due to a combination of factors, especially the increase of ... Chiropractic care may help reduce the frequency and severity of asthma attacks. Naturally, we cant make any promises, however ... published in the Journal of Vertebral Subluxation Research documented the results experienced by 81 children with asthma who ...
National Institute of Environmental Health Sciences: Asthmaexternal icon. *Environmental Protection Agency: Asthmaexternal icon ... Quickstats: Percentage of All Emergency Department Visits Made by Patients with Asthma, by Sex and Age Group - National ... Current Asthma Prevalence by Weight Status Among Adults: United States, 2001-2014 ... Percent of visits to office-based physicians with asthma indicated on the medical record: 7.1% ...
... makes it hard to breathe. But with treatment, the condition can be managed so that kids can still do the things they ... How Is Asthma Treated?. Theres no cure for asthma, but it can be managed to prevent flare-ups. Asthma treatment involves two ... Triggers can lead to asthma flare-ups or "attacks.". What Are the Signs and Symptoms of Asthma?. Asthma Flare-Ups. Flare-ups ... What Is Asthma?. Asthma is a condition that causes breathing problems. Kids may cough, wheeze, or be short of breath. This ...
Work-related asthma: Most frequently reported agents associated with work-related asthma cases by asthma classification, 2009- ... Work-related asthma: Most frequently reported agents associated with work-related asthma cases by state, 2009-2012 2017-926 ... Work-related asthma: Number of cases in California, Massachusetts, Michigan, and New York by asthma classification, 2009-2014 ... Work-related asthma: Ten most frequently reported agent categories associated with cases of work-related asthma, 2009-2012 2017 ...
This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth ... Synonyms: Asthma unspecified, Exercise-induced asthma, Exercise-induced asthma (disorder), Asthma, Bronchial, Asthma, ... Exercise induced asthma, Other forms of asthma, Bronchial asthma, ASTHMA NOS W (AC) EXAC, Hyperreactivities, Bronchial, ... Asthma NOS (disorder), Asthma, unspecified, Pneumopathy due to inhalation of other dust NOS, chronic obstructive asthma, ...
... makes it hard to breathe. But with treatment, the condition can be managed so that kids can still do the things they ... The American Academy of Allergy, Asthma, and Immunology offers up-to-date information and a find-an-allergist search tool. ... Learn about asthma, its symptoms, and how to find relief through allergist care and treatment. ... AANs mission is to end the needless death and suffering due to asthma, allergies and related conditions through outreach, ...
State and City Asthma Contacts and Programs. * Historical Information: Asthma at a Glance 2002-2010plus icon * 2010 At A Glance ... Asthma Surveillance dataplus icon * NHIS Asthma Prevalence Dataplus icon *2018 Data ... Evaluation of the ZAP Asthma Project pdf icon[PDF - 1.28 MB]. The ZAP Asthma Project is a complex public-private partnership ... Key Clinical Activities for Quality Asthma Care: Recommendations of the National Asthma Education and Prevention Program. MMWR ...
Asthma Fast Facts for Kids[PDF - 2.15 MB]. Dont Let Asthma Keep You Out of the Game. In this podcast, the Kidtastics talk ... State and City Asthma Contacts and Programs. * Historical Information: Asthma at a Glance 2002-2010plus icon * 2010 At A Glance ... Asthma - Get the Facts!. In this podcast for kids, the Kidtastics talk about basic asthma facts. Listen To This Podcast… (1:45) ... Childhood Asthma. Source: Developed by the DC Department of Health. ©2004.. This video discusses how you can manage asthma to ...
These are called asthma triggers.. Resources for Parents. Know How to Use Your Asthma Inhaler. CDCs National Asthma Control ... State and City Asthma Contacts and Programs. * Historical Information: Asthma at a Glance 2002-2010plus icon * 2010 At A Glance ... Asthma Surveillance dataplus icon * NHIS Asthma Prevalence Dataplus icon *2018 Data ... Asthma is a disease that affects the lungs. It is one of the most common long-term diseases of children. Asthma causes repeated ...
  • An asthma spacer is an add-on device used to increase the ease of administering aerosolized medication from a metered-dose inhaler (MDI). (wikipedia.org)
  • It is one of the most common long-term diseases of children, but adults can have asthma, too. (cdc.gov)
  • That means we diagnose and treat both adults and children, which can be especially helpful for families with multiple allergies or asthma-sufferers. (chw.org)
  • The article suggests that the majority of adults and youths with current asthma would benefit from additional information and training. (cdc.gov)
  • Items included in the following table are related to asthma patient education and medication use for adults with current asthma in Wisconsin. (cdc.gov)
  • Asthma, an airway disease that causes coughing and wheezing, affects both children and adults. (nyc.gov)
  • Over 24 million Americans are currently living with asthma (1 in 12 children and 1 in 13 adults). (cdc.gov)
  • 3 In 2015, over 3,600 children and adults died from asthma. (cdc.gov)
  • Asthma prevalence data among adults and children in every state can that can be displayed in dynamic, customizable map, chart, and table views. (cdc.gov)
  • 2. White GE, Mazurek JM, Storey E. Employed adults asthma who have frequent workplace exposures. (cdc.gov)
  • These tables feature the latest national and state statistics on the burden of asthma among children and adults. (cdc.gov)
  • Children have 2 times the rate of emergency department visits and hospitalizations for asthma as adults. (nih.gov)
  • In 2010, 18.7 million adults and 7 million children in the United States had asthma. (ct.gov)
  • Asthma prevalence in Connecticut adults and children has been higher than national prevalence rates since the year 2000. (ct.gov)
  • If you'll be going somewhere by yourself - like sleepover camp - have your parents talk to the camp counselors and other adults there about your asthma. (kidshealth.org)
  • Children with asthma usually develop emphysema as adults. (nea.org)
  • Asthma and Allergy Foundation of America offers support groups for parents, pre-teens and teens, adults, and those with food allergies. (healthfinder.gov)
  • Find out what you can do to help children and adults to better manage their asthma. (healthfinder.gov)
  • Deaths due to asthma are rare and are thought to be largely preventable, particularly among children and young adults. (cdc.gov)
  • These tables feature the national and state statistics on the burden of asthma among children and adults previously published on the Most Recent Asthma Data website. (cdc.gov)
  • Also, phthalates in certain types of PVC are associated with asthma in children and adults. (wikipedia.org)
  • The Centers for Disease Control and Prevention estimate that 1 in 11 children and 1 in 12 adults have asthma in the United States of America. (wikipedia.org)
  • GAN is a worldwide network of study centres continuing the global surveillance of asthma in children established by ISAAC, and now including the surveillance of asthma in adults. (wikipedia.org)
  • In children and adults with established asthma, viral upper respiratory tract infections (URIs), especially HRVs infections, can produce acute exacerbations of asthma. (wikipedia.org)
  • From 2000 through 2010, the rate of pediatric hospital stays for asthma declined from 165 to 130 per 100,000 population, respectively, whereas the rate for adults remained about 119 per 100,000 population. (wikipedia.org)
  • Rates of asthma-related hospital admissions in 2010 were more than three times higher among African American children and two times higher for African American adults compared with White and Asian and Pacific Islander people. (wikipedia.org)
  • In the U.S., 8% of adults and 10% of children have asthma. (wikipedia.org)
  • It recommended the drug as an option for treating severe, persistent allergic asthma in adults, adolescents and children following additional analyses and submission of a patient access scheme (PAS) by Novartis, the manufacturer. (wikipedia.org)
  • Zafirlukast is FDA-approved for the prevention and treatment of asthma in adults and children older than 5 years old. (wikipedia.org)
  • At age 7, asthma was diagnosed based on reported symptoms and measurement of lung function with spirometric tests according to American Thoracic Society and European Respiratory Society guidelines. (mdmag.com)
  • READ: Symptoms of asthma include coughing, wheezing, shortness of breath, chest tightness or phlegm production when {child's name} did not have a cold or respiratory infection. (cdc.gov)
  • Infections linked to influenza (flu), colds, and respiratory syncytial virus (RSV) can trigger an asthma attack. (cdc.gov)
  • Air Pollution and Respiratory Health-Outdoor Air Pollution Here you will find information about asthma and indoor and outdoor air pollution from Federal, state, and private resources. (cdc.gov)
  • Respiratory Health and Air Pollution Transportation-related pollutants are one of the largest contributors to unhealthy air quality, especially among children with asthma. (cdc.gov)
  • Air Pollution and Respiratory Health-Indoor Air Pollution This site provides information and frequently asked questions from federal, state, and private resources about asthma and indoor and outdoor air pollution. (cdc.gov)
  • Asthma in general is an incurable condition that deals with the respiratory system which result to the narrowing of airway. (selfgrowth.com)
  • Respiratory infections like influenza (flu), can be very serious for you, even if your asthma is mild or your symptoms are well-controlled by medication. (cdc.gov)
  • The Illinois Asthma Program funds the Respiratory Health Association (RHA) to educate caregivers through its educational series, Asthma Management. (cdc.gov)
  • Asthma camps are led by respiratory therapists and nurses who provide medical education, management and oversight for attendees. (wikipedia.org)
  • Asthma Canada provides a free call-back service connecting Canadians with Certified Respiratory Educators (1-866-787-4050), and distributes information at community centres, health fairs and other public events. (wikipedia.org)
  • Feline asthma is a common allergic respiratory disease in cats, affecting at least one percent of all adult cats worldwide. (wikipedia.org)
  • Feline asthma and other respiratory diseases may be prevented by cat owners by eliminating as many allergens as possible. (wikipedia.org)
  • Retrieved April 4, 2013, from http://pets.webmd.com/cats/asthma-symptoms-cats Feline Asthma & Other Respiratory Disorders. (wikipedia.org)
  • The Global Asthma Network has established worldwide networks with organizations concerned with health in developing countries such as the World Health Organization (WHO), the International Union Against Tuberculosis and Lung Disease, the Forum of International Respiratory Societies(FIRS), the International Congress on Pediatric Pulmonology (CIPP), NCD Child and the American Thoracic Society (ATS). (wikipedia.org)
  • Aspirin-induced asthma, also termed Samter's triad, Samter's syndrome, aspirin-exacerbated respiratory disease (AERD), and recently by an appointed task force of the European Academy of Allergy and Clinical Immunology/World Allergy Organization (EAACI/WAO) Nonsteroidal anti-inflammatory drugs-exacerbated respiratory disease (N-ERD). (wikipedia.org)
  • The symptoms of respiratory reactions in this syndrome are hypersensitivity reactions to NSAIDs rather than the typically described true allergic reactions that trigger other common allergen-induced asthma, rhinitis, or hives. (wikipedia.org)
  • The respiratory reactions to aspirin vary in severity, ranging from mild nasal congestion and eye watering to lower respiratory symptoms including wheezing, coughing, an asthma attack, and in rare cases, anaphylaxis. (wikipedia.org)
  • Overexpression of both the cysteinyl leukotriene receptor 1 and the leukotriene C4 synthase enzyme has been shown in respiratory tissue from patients with aspirin-induced asthma, which likely relates to the increased response to leukotrienes and increased production of leukotrienes seen in the disorder. (wikipedia.org)
  • Furthermore, children who experience severe viral respiratory infections early in life have a high possibility of having asthma later in their childhood. (wikipedia.org)
  • Very severe acute asthma (termed "near-fatal" as there is an immediate risk to life) is characterised by a peak flow of less than 33% predicted, oxygen saturations below 92% or cyanosis (blue discoloration, usually of the lips), absence of audible breath sounds over the chest ("silent chest"), reduced respiratory effort and visible exhaustion or drowsiness. (wikipedia.org)
  • Being exposed to things in the environment, like mold or dampness, some allergens such as dust mites, and secondhand tobacco smoke have been linked to developing asthma. (cdc.gov)
  • Individuals within disadvantaged populations also may face substandard housing and work conditions that place them at greater risk for frequent and prolonged exposure to environmental allergens and irritants that worsen asthma. (nih.gov)
  • Peter and the other patients were caught in an epidemic of thunderstorm asthma - a rare phenomenon that's caused by a perfect storm of weather conditions and airborne allergens. (abc.net.au)
  • The airways of people who have asthma are extra sensitive to the things they're allergic to (allergens). (familydoctor.org)
  • If animal allergens trigger your asthma, ask for a room that has never had pets in it. (kidshealth.org)
  • Asthma is associated with exposure to indoor allergens. (wikipedia.org)
  • But just like any disease, the severity of an asthma attack can be propelled by more than just the allergens, common factors include: obesity, stress, parasites and pre-existing heart conditions. (wikipedia.org)
  • The mechanisms behind allergic asthma-i.e., asthma resulting from an immune response to inhaled allergens-are the best understood of the causal factors. (wikipedia.org)
  • In both people with asthma and people who are free of the disease, inhaled allergens that find their way to the inner airways are ingested by a type of cell known as antigen-presenting cells, or APCs. (wikipedia.org)
  • Although there has been some discussion as to whether dust mite avoidance measures will result in a clinically relevant outcome the resulting debate has given rise to a recommendation by the National Heart, Lung and Blood Institute that an asthma management plan should include avoidance of as many allergens as possible to which the individual is sensitive. (wikipedia.org)
  • This report and others also assert that no single specific measure is sufficient to reduce allergens: An allergen reduction plan, which encompasses a variety of approaches is necessary to address management of asthma symptoms. (wikipedia.org)
  • Risk Factors for asthma in children include: Babies born too early, born by C-section, Having Atopy, Allergens, Exposure to smoke and pollution, having a parent who has Asthma, and genetics. (wikipedia.org)
  • If you start wheezing or coughing during exercise, or if physical exertion makes it difficult for you to breathe, you may have exercise-induced asthma. (acaai.org)
  • Doctors help people with exercise-induced asthma manage physical activity, not avoid it. (kidshealth.org)
  • Exercise-Induced Asthma - Duration: 103 seconds. (youtube.com)
  • But some people (including those who do not have asthma) have asthma symptoms only during or after exercise: This is known as exercise-induced asthma (EIA) (also called exercise-induced bronchoconstriction, or EIB). (kidshealth.org)
  • People with exercise-induced asthma often start having symptoms 5-10 minutes after they begin working out. (kidshealth.org)
  • If you have exercise-induced asthma, your doctor might want you to take asthma medicine before being really active. (kidshealth.org)
  • How Can I Deal With Exercise-Induced Asthma? (kidshealth.org)
  • Study finds other conditions mimic exercise-induced asthma. (runnersworld.com)
  • Short-acting β2-agonists are used to treat exercise-induced asthma, and for asthma patients to get a quick relief of symptoms. (wikipedia.org)
  • Long-lasting β2-agonists are not used to treat exercise-induced asthma. (wikipedia.org)
  • In an effort to improve asthma prevention and care, investigators have developed a new quantitative tool, the Pediatric Asthma Risk Score (PARS), to help predict pediatric asthma better than current standard test Asthma Predictive Index (API). (mdmag.com)
  • The ZAP Asthma Project is a complex public-private partnership focusing on reducing the incidence of negative health outcomes associated with pediatric asthma. (cdc.gov)
  • Results are promising, showing fewer asthma-related pediatric emergency room visits and fewer hospital admissions. (nyc.gov)
  • Pediatric/Adult Asthma Coalition of New Jersey Asthma Action Plans in English, Spanish, or English/Spanish external icon (links to electronic fillable forms are on the right side of page). (cdc.gov)
  • The heterogeneous nature of the clinical manifestations and therapeutic responses of asthma in both adult and pediatric patients indicate that it may be more of a syndrome rather than a specific disease entity. (nih.gov)
  • If you experience wheezing, coughing, chest tightness or shortness of breath at work, you may have occupational asthma. (acaai.org)
  • Most people with asthma experience a tight feeling in the chest, shortness of breath, coughing or wheezing at some point in their life. (lung.org)
  • The cardinal symptoms of an asthma attack are shortness of breath (dyspnea), wheezing, and chest tightness. (wikipedia.org)
  • Can Shortness of Breath and Chest Tightness Be an Asthma Symptom? (runnersworld.com)
  • Play media Asthma is characterized by recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing. (wikipedia.org)
  • Cardiac asthma is a medical diagnosis of wheezing, coughing or shortness of breath due to congestive heart failure. (wikipedia.org)
  • Asthma is a disease that affects your lungs. (cdc.gov)
  • Get the basics on how asthma affects your body and the impact of this condition. (lung.org)
  • There are still about 1500 deaths a year from asthma in the UK, many of which may be preventable, and asthma affects about eight million people in the UK at some stage in their lives. (bmj.com)
  • The Asthma Wizard will guide you through fun activities to help you learn all about asthma and how it affects kids. (healthfinder.gov)
  • According to the World Health Organization, asthma affects 235 million people worldwide. (wikipedia.org)
  • Asthma affects at least 330 million people worldwide, causing an estimated 250,000 deaths annually (all ages). (wikipedia.org)
  • Asthma affects approximately 7% of the population of the United States and causes approximately 4,210 deaths per year. (wikipedia.org)
  • U.S.-born Mexican populations, for example, have higher asthma rates than non-U.S. born Mexican populations that are living in the U.S. Asthma affects approximately 5% of the United Kingdom's population. (wikipedia.org)
  • Having a doctor check how well your lungs work and check for allergies can help you find out if you have asthma. (cdc.gov)
  • The doctor may also do a breathing test, called spirometry, to find out how well your lungs are working by testing how much air you can breathe out after taking a very deep breath before and after you use asthma medicine. (cdc.gov)
  • In asthma, air doesn't move through the lungs the way it should. (kidshealth.org)
  • Most asthma medicines are breathed directly into the lungs (inhaled), but some are pills or liquids. (kidshealth.org)
  • One in 13 Americans (nearly 25 million) lives with asthma, a disease affecting the lungs and causing repeated episodes of wheezing, breathlessness, chest tightness, and coughing. (cdc.gov)
  • While larger pollen grains are usually filtered by hairs in the nose, the smaller pollen fragments are able to pass through and enter the lungs, triggering the asthma attack. (wikipedia.org)
  • Spacers slow down the speed of the aerosol coming from the inhaler, meaning that less of the asthma drug impacts on the back of the mouth and somewhat more may get into the lungs. (wikipedia.org)
  • Through its action on inflammatory cells in the lungs, zafirlukast reduces the production of inflammatory mediators that are implicated in the pathogenesis of asthma. (wikipedia.org)
  • To diagnose asthma, doctors will ask questions about a child's health, problems with breathing, and family medical history. (kidshealth.org)
  • For example, if pet dander or mold in your home trigger your child's asthma symptoms, you can make your home asthma-safe by changing the linens often, vacuuming regularly, and keeping the family pet out of your child's bedroom. (kidshealth.org)
  • How long has it been since you last talked to a doctor or other health professional about {child's name} asthma? (cdc.gov)
  • The doctor may suggest keeping an asthma diary to record your child's symptoms, medicines , and peak flow readings. (kidshealth.org)
  • How Can I Manage My Child's Asthma? (kidshealth.org)
  • Learn as much as you can, talk to others living with asthma, read up on asthma, and discuss any concerns with your child's doctor. (kidshealth.org)
  • The diary helps you to keep track of your child's asthma symptoms (when they happen), need for medicines, and more. (kidshealth.org)
  • Developing an Asthma Action Plan A doctor can help you create an asthma action plan, which lays out the symptoms you should watch for and steps to take to get your child's breathing under control. (webmd.com)
  • Managing Your Child's Asthma at School If your child has asthma, it's important that her school knows how to recognize and treat symptoms. (webmd.com)
  • Talk with your child's care team if you have questions about whether your child will outgrow asthma. (massgeneral.org)
  • Your child's care team can help create and explain an Asthma Action Plan. (massgeneral.org)
  • In 2007, asthma cost the U.S. about $56 billion in medical costs, lost school and work days, and early deaths. (cdc.gov)
  • The program's goals include reducing the number of deaths, hospitalizations, emergency department visits, school days or workdays missed, and limitations on activity due to asthma. (cdc.gov)
  • Low-income populations, minorities, and children living in inner cities experience more emergency department visits, hospitalizations, and deaths due to asthma than the general population. (cdc.gov)
  • National data is available on asthma prevalence, activity limitation, days of work or school lost, rescue and control medication use, asthma self-management education, physician visits, emergency department visits, hospitalizations due to asthma, and deaths due to asthma from National Center for Health Statistics (NCHS) surveys and the Vital Statistics System. (cdc.gov)
  • The rates of hospitalizations and deaths due to asthma are both 3 times higher among African Americans than among whites. (nih.gov)
  • Women account for nearly two-thirds of all deaths due to asthma in the United States. (nih.gov)
  • In general, these disadvantaged and at-risk populations experience above-average rates of emergency department visits, hospitalizations, and deaths that are much higher than differences in asthma prevalence would suggest. (nih.gov)
  • In the U.S., more than 10 million school days are lost each year because of asthma, which also causes over 5,000 deaths annually. (nea.org)
  • The rate of asthma deaths decreased from 15 per million in 2001 to 10 per million in 2018. (cdc.gov)
  • Asthma deaths have decreased over time. (cdc.gov)
  • The more you can learn about asthma, the better you and your loved ones can manage living with this disease. (lung.org)
  • Learn about asthma, its symptoms, and how to find relief through allergist care and treatment. (kidshealth.org)
  • Do you want to learn about asthma? (cdc.gov)
  • You can search this site to learn about asthma basics external icon . (cdc.gov)
  • Go to the section For Kids to download a fun booklet with games that can help your child learn about asthma. (cdc.gov)
  • To help your child learn about asthma, please visit, Kids . (cdc.gov)
  • State asthma programs and their partners work together to create professional development and training opportunities for school district staff, administrators, teachers, parents, and coaches to learn about asthma and indoor air quality. (cdc.gov)
  • The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma. (ingentaconnect.com)
  • These include our Primary Immunodeficiency Program, Asthma Plus Program and clinical nutrition services. (chw.org)
  • The Collaboration on Severe Asthma (COSA) is a global platform for the exchange of scientific and clinical information on severe asthma to better understand the complexities of the disease and continually improve strategies for optimal care of the severe asthma patient. (worldallergy.org)
  • The National Heart, Lung, and Blood Institute (NHLBI) Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma includes recommendations by medical and public health experts to aid in the clinical practice of managing asthma. (cdc.gov)
  • Brittle asthma: a separate clinical phenotype of asthma? (wikipedia.org)
  • Gaps in the implementation of clinical practice guidelines for asthma contribute to the ongoing problem of asthma-related health disparities among at-risk groups. (nih.gov)
  • Disparities in the burden and care of asthma suggest that culturally competent clinical and educational approaches, such as those identified in the GIP Report , are needed to implement the EPR-3 asthma guidelines in high-risk groups and to improve access to quality asthma care. (nih.gov)
  • State asthma programs help schools connect students with clinical care in a variety of ways, including giving school nurses access to electronic health record (EHR) systems, developing and using asthma action plans in schools, and offering training and technical assistance to school-based health centers. (cdc.gov)
  • The response rates among treated severe "allergic" asthma patients are 60-80% or higher, probably depending on the patient screening procedures used by the various clinical groups of different specialties. (wikipedia.org)
  • In August 2010, the National Institute for Clinical Excellence (NICE) in the United Kingdom ruled that omalizumab should not be prescribed on the National Health Service (NHS) to children under 12, causing widespread condemnation from asthma charities. (wikipedia.org)
  • Clinical Asthma. (wikipedia.org)
  • The care team can also talk about how to prevent asthma symptoms through lifestyle changes. (massgeneral.org)
  • The concept is to harness advances in biomedical research in all fields in seeking to treat or prevent asthma. (wikipedia.org)
  • The Global Asthma Network's mission is: To prevent asthma and improve asthma care globally with a focus on low- and middle-income countries. (wikipedia.org)
  • You can control your asthma by knowing the warning signs of an asthma attack, staying away from things that cause an attack, and following your doctor's advice. (cdc.gov)
  • Take your medicine exactly as your doctor tells you and stay away from things that can trigger an attack to control your asthma. (cdc.gov)
  • Asthma medicines come in two types-quick-relief and long-term control. (cdc.gov)
  • Quick-relief medicines control the symptoms of an asthma attack. (cdc.gov)
  • Remember - you can control your asthma . (cdc.gov)
  • Follow @CDCasthma on Twitter to learn more about helping people with asthma live healthier lives by gaining control over their asthma. (cdc.gov)
  • You can control your asthma and avoid an attack by taking your medicine exactly as your doctor or other medical professional tells you to do and by avoiding things that can cause an attack. (cdc.gov)
  • Long-term control medicines manage asthma by preventing symptoms from happening. (kidshealth.org)
  • The Community Guide provides evidence-based recommendations regarding asthma control. (cdc.gov)
  • CDC provided funding to seven inner-city sites under the Controlling Asthma in American Cities Project (CAACP) to support the translation of scientific advances in the treatment of asthma into innovative, comprehensive approaches to improve asthma control among urban children up to 18 years of age in underserved communities with a high asthma burden. (cdc.gov)
  • This site provides information on potentially effective interventions for asthma control, including methodology for identification of the interventions, results, lessons learned, information on the interventions themselves, a bibliography, and case studies of interventions. (cdc.gov)
  • This helps them control their asthma. (cdc.gov)
  • But lessening exposure whenever possible can help keep asthma symptoms under control. (kidshealth.org)
  • NACP was created in 1999 to help the millions of people with asthma in the United States gain control over their disease. (cdc.gov)
  • The program has improved asthma treatment, management, and control in the U.S. (cdc.gov)
  • Intensive asthma self-management education can improve asthma symptom control for individuals whose asthma is not well-controlled with medical management based upon the NAEPP Guidelines. (cdc.gov)
  • This survey, sponsored by the National Center for Environmental Health (NCEH), Centers for Disease Control and Prevention , examines the health, socioeconomic, behavioral, and environmental predictors that relate to better control of asthma. (cdc.gov)
  • The above text is adapted from the "You Can Control Your Asthma" pdf icon [PDF - 4074 KB] full-color brochure and is suitable for downloading and printing. (cdc.gov)
  • The National Asthma Control Program, in partnership with the Environmental Protection Agency, has created a four-part Webinar series on program evaluation basics. (cdc.gov)
  • and introduce the six steps of the CDC Framework for Program Evaluation using examples that are relevant to state partners of the National Asthma Control Program. (cdc.gov)
  • Stephanie - My asthma is under control and I live a much happier life - Duration: 31 seconds. (youtube.com)
  • This podcast features real-life success stories of students with asthma who, thanks to their schools' implementation of asthma-friendly policies and programs, now have their asthma under control. (cdc.gov)
  • Learn how you can control your asthma at home. (cdc.gov)
  • Regardless of age, race, ethnicity, gender, class, income, or personal history, advances in asthma treatment mean that asthma control is achievable for nearly all persons with asthma, but only if clinicians and patients join together to follow the asthma guidelines. (nih.gov)
  • Your doctor will work with you to create an action plan to control your asthma. (familydoctor.org)
  • People who learn how to control their asthma are less likely to have exacerbations. (bmj.com)
  • And they miss a lot - in the U.S., more than 13 million schooldays are missed each year because of asthma, according to the Centers for Disease Control and Prevention (CDC). (kidshealth.org)
  • When kids' asthma is under control, they have far fewer flare-ups. (kidshealth.org)
  • Exercising With Asthma Discover which forms of exercise are best for people with asthma and how to control asthma while exercising. (webmd.com)
  • But you have to keep your asthma in control. (webmd.com)
  • There's no cure, but people with asthma can control their disease and live healthy, active lives. (mass.gov)
  • When you control your asthma, you will breathe easier, be as active as you would like, sleep well, stay out of the hospital, and be free from coughing and wheezing. (cdc.gov)
  • The program has improved asthma treatment, management, and control in the U.S. CDC's funded programs have improved the quality of asthma care, improved asthma management in schools, and fostered policies to help reduce air pollution. (cdc.gov)
  • A 35-page guide to assist asthma program staff in state health departments to develop and implement asthma control programs. (cdc.gov)
  • We're supporting initiatives across the country to provide comprehensive asthma control in school settings - and ultimately create more asthma-friendly schools. (cdc.gov)
  • The Missouri Asthma Prevention and Control Program (MAPCP) implemented Teaming Up for Asthma Control (TUAC) in 2014 to train school nurses to provide asthma education, measure lung capacity, and assess inhalation technique in students with persistent asthma. (cdc.gov)
  • The New Mexico Asthma Control Program (NMACP) partners with University of New Mexico Envision school-based health centers to support schools in providing comprehensive asthma control activities. (cdc.gov)
  • The important thing to remember is that you can control your asthma . (cdc.gov)
  • This site provides information about asthma management and treatment options to help you take control of your asthma. (cdc.gov)
  • The goals of ACMA are to increase patient awareness about how to achieve optimal asthma control, address communication and advocacy needs of asthma patients, and build a network of patient volunteers dedicated to improving asthma care and education. (wikipedia.org)
  • It has been used to try to control severe allergic asthma, which does not respond to high doses of corticosteroids. (wikipedia.org)
  • Stimulants have been used in medicine for many conditions including obesity, sleep disorders, mood disorders, impulse control disorders, asthma, nasal congestion and as anesthetics. (wikipedia.org)
  • Plus see how you can be an advocate for policies that will help people with asthma breathe easier in the future. (lung.org)
  • They wish to raise awareness of the seriousness of asthma, the risks to people with asthma and the dangers of bushfire smoke, so no one else has to go through what they're experiencing. (thatslife.com.au)
  • Join our thriving asthma community of primary carers and specialists working together to improve the lives of people with asthma. (nationalasthma.org.au)
  • No one knows exactly why some people develop asthma. (kidshealth.org)
  • People with asthma may have a parent or other close relative with asthma. (kidshealth.org)
  • Exercise can help people stay healthier overall (in fact, many pro athletes have asthma! (kidshealth.org)
  • Healthy People is a statement of U.S. health objectives designed to identify the most significant preventable threats to health, including asthma, and to establish national goals to reduce these threats. (cdc.gov)
  • This site provides a toolkit to help advocates in schools and school districts persuade people in their schools and communities of the importance of asthma-friendly schools. (cdc.gov)
  • This site presents sample purchasing specifications for the purchase of services for people with asthma from managed care organizations by state agencies administering Medicaid, other state agencies, and other managed care purchasers. (cdc.gov)
  • These are things that are harmless to most people, but can cause flare-ups in kids with asthma. (kidshealth.org)
  • Teaching people how to manage asthma on their own is one of the most important parts of controlling the disease nationwide. (cdc.gov)
  • In general, people with asthma aren't getting action plans from their doctors. (cdc.gov)
  • Tobacco smoke is unhealthy for everyone, especially people with asthma. (cdc.gov)
  • If you have asthma, people should never smoke near you, in your home, in your car, or wherever you may spend a lot of time. (cdc.gov)
  • People with asthma are not allergic to their pet's fur, so trimming the pet's fur will not help your asthma. (cdc.gov)
  • This fact sheet provides information for people with asthma on understanding and using outdoor air quality warnings. (cdc.gov)
  • Hear from people who have successfully developed asthma management programs that have improved health outcomes in their communities. (cdc.gov)
  • Asthma and Outdoor Air Pollution pdf icon [PDF - 499 KB] external icon This fact sheet provides information for people with asthma on understanding and using outdoor air quality warnings. (cdc.gov)
  • Dr. Joy Hsu explains the importance of teaching people with asthma how to use their medications properly and shares an instructional tool CDC created to assist physicians. (cdc.gov)
  • Mold People with asthma may be more sensitive to mold. (cdc.gov)
  • Your opinion about this publication will help us to better understand the information needs of people interested in reducing the burden of asthma in Connecticut. (ct.gov)
  • For some people, strong emotions or stress can trigger an asthma attack. (familydoctor.org)
  • Asthma is increasing every year in the U.S., and now afflicts about one in twelve people. (healthfinder.gov)
  • Most people with asthma have symptoms when they exercise. (kidshealth.org)
  • For some people, asthma symptoms last for hours after they exercise, or happen only after they stop exercising. (kidshealth.org)
  • Doctors no longer tell people with asthma to avoid exercising and, in fact, often recommend it as part of asthma treatment. (kidshealth.org)
  • People that have experienced a life threatening asthma attack might end up being asthma free and might only experience its attack once in blue moon. (selfgrowth.com)
  • Today, CDC funds the health departments in 24 states and Puerto Rico to ensure the availability of and access to guidelines-based medical management and pharmacotherapy for all people with asthma and to address the intersection of public health and health care through funding state programs and national organizations, promoting asthma quality measures, and informing policy makers about the burden of asthma. (cdc.gov)
  • In 2015, 358 million people globally had asthma, up from 183 million in 1990. (wikipedia.org)
  • It has been found 95% of those that were affected by thunderstorm asthma had a history of hayfever, and 96% of those people had tested positive to grass pollen allergies, particularly rye grass. (wikipedia.org)
  • Thunderstorm asthma': Four people now believed dead, could have been more, minister says" ABC News, 23 November 2016. (wikipedia.org)
  • Asthma Canada, formerly the Asthma Society of Canada, is a non profit charity dedicated to enhancing the quality of life and health for people living with asthma and associated allergies through education and research. (wikipedia.org)
  • Asthma Canada represents over three million Canadians living with asthma, along with their caregivers and all others impacted by asthma, and also provides resources for people suffering from allergies. (wikipedia.org)
  • In 1989 it became the National Asthma Campaign and in 2004, when support for people with asthma had become more important, it changed its name to Asthma UK. (wikipedia.org)
  • In January 2017 it published the results of a survey of 4,650 patients showing that about 3.6 million people across the UK were not getting adequate routine care for their asthma. (wikipedia.org)
  • Whereas people with asthma can discreetly keep an MDI close-by at all times, the bulkiness of spacers can limit patient's utilization of spacers outside of the home. (wikipedia.org)
  • As of 2011, ~235 million people worldwide were affected by asthma, and approximately 250,000 people die per year from the disease. (wikipedia.org)
  • In 2005, asthma affected more than 22 million people, including 6 million children, and accounted for nearly 500,000 hospitalizations that same year. (wikipedia.org)
  • 5.7 million people had an asthma diagnosis and were prescribed 32.6 million asthma-related prescriptions. (wikipedia.org)
  • Allergy Standards Limited is an International Standards and Certification Body that prepares independent standards for a wide range of products to declare their suitability for people whose lives are affected by allergies and asthma. (wikipedia.org)
  • Asma en Espanol MyFoodAllergies.net - online resource for people with food allergies. (wikipedia.org)
  • It has been approved for treating people 12 years and older with severe or moderate to severe allergic asthma in more than 90 countries, since its first of such approval in 2002 in Australia. (wikipedia.org)
  • New measures in HEDIS 2013 are "Asthma Medication Ratio," "Diabetes Screening for People With Schizophrenia and Bipolar Disorder Who Are Using Antipsychotic Medications," "Diabetes Monitoring for People With Diabetes and Schizophrenia," "Cardiovascular Monitoring for People With Cardiovascular Disease and Schizophrenia," and "Adherence to Antipsychotic Medications for Individuals With Schizophrenia. (wikipedia.org)
  • Depending on the country about 1-18% of people have asthma. (wikipedia.org)
  • People with asthma are shown to have a higher prevalence of Toxocara seropositivity. (wikipedia.org)
  • She was just found to have a asthma for prednisone liquid finally inflammatory needle arginine and i' precursor. (espacerugby.com)
  • Although much research has been done since, the inflammatory component of asthma was recognized only in the 1960s. (wikipedia.org)
  • During re-exposure, the agent cross-links specific antibodies on mast cells and activates them to release inflammatory mediators leading to asthma symptoms. (cdc.gov)
  • There are several mechanisms that can be combined to generate an asthma attack, including specific IgE antibodies, activated inflammatory cells, neurogenic mechanisms, hyperresponsiveness and individual hormonal imbalances. (wikipedia.org)
  • The conversion of cell membrane arachidonic acid (20:4n-6) to omega-6 prostaglandin and omega-6 leukotriene eicosanoids during the inflammatory cascade provides many targets for pharmaceutical drugs to impede the inflammatory process in atherosclerosis, asthma, arthritis, vascular disease, thrombosis, immune-inflammatory processes, and tumor proliferation. (wikipedia.org)
  • PMID 18587040 Forouzan A, Masoumi K, Haddadzadeh Shoushtari M, Idani E, Tirandaz F, Feli M, Assarehzadegan MA, Asgari Darian A. An overview of thunderstorm-associated asthma outbreak in southwest of Iran. (wikipedia.org)
  • View our tools and resources for health professionals and volunteers to provide guideline-based asthma care and education. (lung.org)
  • We are the national authority for asthma knowledge, setting the standard for asthma care. (nationalasthma.org.au)
  • However, many who suffer from asthma report improvement by receiving chiropractic care. (google.com)
  • In fact, research published in the Journal of Vertebral Subluxation Research documented the results experienced by 81 children with asthma who received chiropractic care. (google.com)
  • With medicine and the right care plan, asthma symptoms can be managed so that kids and teens can do just about anything they want to do. (kidshealth.org)
  • Asthma Care in the Community. (wikipedia.org)
  • You can find excellent asthma care at HHC, where we are working aggressively to help New Yorkers manage the disease. (nyc.gov)
  • You can find specialized asthma care for children at our Child Health Centers . (nyc.gov)
  • The 2007 National Asthma Education and Prevention Program (NAEPP) Guidelines are evidence-based guidelines for asthma management that significantly improve asthma care. (cdc.gov)
  • Asthma symptoms and health care use can be significantly reduced by following the NAEPP guidelines for medical management. (cdc.gov)
  • CDC's Strategies for Addressing Asthma in Homes guide defines core components of home visits (who visits, what education occurs in home, how the home environment is assessed, which/how linkages to care are beneficial). (cdc.gov)
  • This study explores the content of care and health care experiences of persons with asthma. (cdc.gov)
  • Establish strong links with asthma care clinicians to ensure appropriate and ongoing medical care. (cdc.gov)
  • This podcast will assist health care providers in supporting asthma patients so they can be symptom-free and fully active while traveling. (cdc.gov)
  • Economic, social, and cultural factors-ranging from lack of access to quality health care to differences in health beliefs between patients and their doctors-add to the greater asthma burden among these groups. (nih.gov)
  • Despite their higher burden of disease, access to medical care for asthma and the quality of care provided is often lower among minority and socioeconomically disadvantaged populations. (nih.gov)
  • Examples of such approaches include the Physician Asthma Care Education (PACE) Program and multipronged strategies for addressing exposure to environmental factors that worsen asthma at home, school, or work. (nih.gov)
  • It will require innovative and sustained efforts at multiple levels to translate, tailor, and deliver effective asthma care to diverse populations in line with the recommendations of the EPR-3 guidelines and its companion GIP Report. (nih.gov)
  • If you think your asthma care would be too hard for you to manage at camp, there may be a solution. (kidshealth.org)
  • That way, if your asthma flares up , you will get the care you need so that you can go back to having fun! (kidshealth.org)
  • Use the checklist to find out how well your child-care setting assists children with asthma. (healthfinder.gov)
  • what the school's rules are for kids old enough to handle asthma care (can kids keep an inhaler on hand or do they have to go the health office to use it? (kidshealth.org)
  • who handles asthma care if your child isn't old enough to take care of monitoring and treatment. (kidshealth.org)
  • If your child does not have an Asthma Action Plan, ask the care team to create one with you. (massgeneral.org)
  • The network aims to improve asthma care globally, with a focus on low- and middle-income countries, through enhanced surveillance, research collaboration, capacity building and access to quality-assured essential medicines. (wikipedia.org)
  • The network will achieve this through enhanced surveillance, research, capacity building, and access to effective asthma care including quality assured essential medicines. (wikipedia.org)
  • World Asthma Day is an annual event organized by the Global Initiative for Asthma (GINA) to improve asthma awareness and care around the world. (wikipedia.org)
  • GINA conducts continuous review of scientific publications on asthma and is a leader in disseminating information about the care of patients with asthma. (wikipedia.org)
  • It organizes several activities famed at improving asthma patients' well-being, including: An annual trek Annual sports meet Health check-up scheme for members Provision of emergency inhalers at a discount rate Nebulizers for rent at minimal cost Newsletter (Asthma Times) offering information on asthma and asthma care Anti-tobacco campaigns Asthma camps and community programmes The association also works to increase awareness about asthma in India, particularly in Mumbai. (wikipedia.org)
  • Like other leukotriene receptor antagonists, zafirlukast is thought to be useful for the long-term treatment of asthma, but it is generally less effective than inhaled glucocorticoids as monotherapy (which are the standard of care) or long-acting beta-2 agonists in combination therapy. (wikipedia.org)
  • The inaugural World Asthma Day was held in 1998. (wikipedia.org)
  • She entered the world of environmental activism in 1998 after her three-month-old son suffered an asthma attack despite having no family history of asthma. (wikipedia.org)
  • 1999). Difficult asthma. (wikipedia.org)
  • Surveillance for Asthma - United States, 1980-1999. (cdc.gov)
  • Established in 1999, it is the largest private funder of asthma research, having awarded over $100,000,000 in grant funds to 175 scientists. (wikipedia.org)
  • The NACP funds states, cities, school programs, and non-government organizations to help them improve surveillance of asthma, train health professionals, educate individuals with asthma and their families, and explain asthma to the public. (cdc.gov)
  • NACP works to support students with asthma, so they can miss fewer school days and participate in more school activities. (cdc.gov)
  • Working with CDC Healthy Schools, NACP has developed strategies to help asthma programs, school personnel, and partners work together to create asthma-friendly schools. (cdc.gov)
  • Read frequently asked questions about managing asthma. (healthfinder.gov)
  • Self-managing asthma day to day is important to breathe well, stay active, and keep asthma symptoms at bay. (webmd.com)
  • It demonstrated that the suffering and waste of resources caused by not managing asthma effectively are much greater than the cost of effective action. (wikipedia.org)
  • Research over the past few years, however, has implicated it in diseases from atherosclerosis to asthma to autism. (wiktionary.org)
  • There are a number of diseases that are very closely related to feline asthma which must be ruled out before asthma can be diagnosed. (wikipedia.org)
  • Yokkaichi asthma (四日市ぜんそく, Yokkaichi zensoku), one of the Four Big Pollution Diseases of Japan, occurred in the city of Yokkaichi in Mie Prefecture, Japan, between 1960 and 1972. (wikipedia.org)
  • In 2012, concern from members of ISAAC and The Union that the Global Non-Communicable Diseases (NCDs) agenda overlooked asthma resulted in the establishment of GAN. (wikipedia.org)
  • The Union and ISAAC collaborated to release the Global Asthma Report at the time of the United Nations High-Level Meeting on Non-Communicable Diseases (NCDs) in New York on 19-20 September 2011. (wikipedia.org)
  • There is no cure for asthma, but the good news is it can be managed and treated so you can live a normal, healthy life. (lung.org)
  • There's no cure for asthma, but it can be managed to prevent flare-ups. (kidshealth.org)
  • Though it is a known fact that no scientific research has found a cure for asthma, but its symptoms can be controlled. (selfgrowth.com)
  • There is no cure for asthma. (wikipedia.org)
  • Its stated mission is to improve treatments for, prevent, and find a cure for asthma. (wikipedia.org)
  • The following data provide an overview of the burden of asthma in Wisconsin (WI) compared with the U.S. (cdc.gov)
  • Not all things are equal when it comes to the burden of asthma. (nih.gov)
  • This guide from the National Heart, Lung, and Blood Institute provides schools with information about planning or maintaining an asthma management program for their students with asthma. (cdc.gov)
  • Asthma-friendly schools are those that make the effort to create safe and supportive learning environments for students with asthma. (cdc.gov)
  • Provide appropriate school health services for students with asthma, ensuring that students take their medicines and learn to use them when appropriate. (cdc.gov)
  • Provide asthma education for students with asthma and awareness programs for students, school staff, parents, and families. (cdc.gov)
  • Offer safe and enjoyable physical education and activities for students with asthma. (cdc.gov)
  • We ended up discussing students with asthma. (nea.org)
  • No one person seemed to know everything you need to know about students with asthma. (nea.org)
  • How adept are you at handling students with asthma? (nea.org)