Asthenozoospermia: A condition in which the percentage of progressively motile sperm is abnormally low. In men, it is defined as Sperm Motility: Movement characteristics of SPERMATOZOA in a fresh specimen. It is measured as the percentage of sperms that are moving, and as the percentage of sperms with productive flagellar motion such as rapid, linear, and forward progression.Food, Preserved: Food that has been prepared and stored in a way to prevent spoilage.Infertility, Male: The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.Spermatozoa: Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.Semen: The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.Oligospermia: A condition of suboptimal concentration of SPERMATOZOA in the ejaculated SEMEN to ensure successful FERTILIZATION of an OVUM. In humans, oligospermia is defined as a sperm count below 20 million per milliliter semen.Sperm Count: A count of SPERM in the ejaculum, expressed as number per milliliter.Pregnancy Rate: The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.Prostatitis: Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment.Masturbation: Sexual stimulation or gratification of the self.Andrology: A scientific or medical discipline concerning the study of male reproductive biology, diseases of the male genital organs, and male infertility. Major areas of interest include ENDOCRINOLOGY; SPERMATOGENESIS; semen analysis; FERTILIZATION; CONTRACEPTION; and CRYOPRESERVATION.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Dictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.Prostate: A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.Fatty Acids, Unsaturated: FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.Fatty Acids: Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)Fatty Acids, Omega-3: A group of fatty acids, often of marine origin, which have the first unsaturated bond in the third position from the omega carbon. These fatty acids are believed to reduce serum triglycerides, prevent insulin resistance, improve lipid profile, prolong bleeding times, reduce platelet counts, and decrease platelet adhesiveness.Membrane Fluidity: The motion of phospholipid molecules within the lipid bilayer, dependent on the classes of phospholipids present, their fatty acid composition and degree of unsaturation of the acyl chains, the cholesterol concentration, and temperature.Docosahexaenoic Acids: C22-unsaturated fatty acids found predominantly in FISH OILS.Ejaculation: The emission of SEMEN to the exterior, resulting from the contraction of muscles surrounding the male internal urogenital ducts.Sexual Abstinence: Refraining from SEXUAL INTERCOURSE.Semen Analysis: The quality of SEMEN, an indicator of male fertility, can be determined by semen volume, pH, sperm concentration (SPERM COUNT), total sperm number, sperm viability, sperm vigor (SPERM MOTILITY), normal sperm morphology, ACROSOME integrity, and the concentration of WHITE BLOOD CELLS.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.BooksPublishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.MEDLINE: The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).Serial Publications: Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Forecasting: The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.Euglenozoa Infections: Infections with the protozoa of the phylum EUGLENOZOA.Infertility: Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.Infertility, Female: Diminished or absent ability of a female to achieve conception.History, 20th Century: Time period from 1901 through 2000 of the common era.Spermatocidal Agents: Chemical substances that are destructive to spermatozoa used as topically administered vaginal contraceptives.Semen Preservation: The process by which semen is kept viable outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).Fetal Movement: Physical activity of the FETUS in utero. Gross or fine fetal body movement can be monitored by the mother, PALPATION, or ULTRASONOGRAPHY.Embryology: The study of the development of an organism during the embryonic and fetal stages of life.Amniocentesis: Percutaneous transabdominal puncture of the uterus during pregnancy to obtain amniotic fluid. It is commonly used for fetal karyotype determination in order to diagnose abnormal fetal conditions.Amniotic Fluid: A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS).Prenatal Diagnosis: Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth.Genitalia, Female: The female reproductive organs. The external organs include the VULVA; BARTHOLIN'S GLANDS; and CLITORIS. The internal organs include the VAGINA; UTERUS; OVARY; and FALLOPIAN TUBES.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Specialization: An occupation limited in scope to a subsection of a broader field.Movement: The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.Internal Medicine: A medical specialty concerned with the diagnosis and treatment of diseases of the internal organ systems of adults.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Influenzavirus A: A genus in the family ORTHOMYXOVIRIDAE causing influenza and other diseases in humans and animals. It contains many strains as well as antigenic subtypes of the integral membrane proteins hemagglutinin (HEMAGGLUTININS) and NEURAMINIDASE. The type species is INFLUENZA A VIRUS.Trans-Activators: Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Recombinant Proteins: Proteins prepared by recombinant DNA technology.Antibody Specificity: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.Immunoglobulin Fab Fragments: Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

Beta-endorphin in serum and seminal plasma in infertile men. (1/72)

AIM: To access beta-endorphin levels in serum as well as seminal plasma in different infertile male groups. METHODS: Beta-endorphin was estimated in the serum and seminal plasma by enzyme-linked immunosorbent assay (ELISA) method in 80 infertile men equally divided into four groups: non-obstructive azoospermia (NOA), obstructive azoospermia (OA), congenital bilateral absent vas deferens (CBVAD) and asthenozoospermia. The results were compared to those of 20 normozoospermic proven fertile men. RESULTS: There was a decrease in the mean levels of beta-endorphin in the seminal plasma of all successive infertile groups (mean +/- SD: NOA 51.30 +/- 27.37, OA 51.88 +/- 9.47, CBAVD 20.36 +/- 13.39, asthenozoospermia 49.26 +/- 12.49 pg/mL, respectively) compared to the normozoospermic fertile control (87.23 +/- 29.55 pg/mL). This relation was not present in mean serum level of beta-endorphin between four infertile groups (51.09 +/- 14.71, 49.76 +/- 12.4, 33.96 +/- 7.2, 69.1 +/- 16.57 pg/mL, respectively) and the fertile control group (49.26 +/- 31.32 pg/mL). The CBVAD group showed the lowest seminal plasma mean level of beta-endorphin. Testicular contribution of seminal beta-endorphin was estimated to be approximately 40%. Seminal beta-endorphin showed significant correlation with the sperm concentration (r = 0.699, P = 0.0188) and nonsignificant correlation with its serum level (r = 0.375, P = 0.185) or with the sperm motility percentage (r = 0.470, P = 0.899). CONCLUSION: The estimation of beta-endorphin alone is not conclusive to evaluate male reproduction as there are many other opiates acting at the hypothalamic pituitary gonadal axis.  (+info)

Association between the apolipoprotein B signal peptide gene insertion/deletion polymorphism and male infertility. (2/72)

In male mice heterozygous for a null apolipoprotein B (apoB), allele infertility was noticed. These data led us to investigate a possible role of APOB gene polymorphism and male infertility in humans. In this case-control study, we searched for an association between the insertion/deletion (I/D) polymorphism of the APOB gene and male infertility in 560 Slovene Caucasian men. The study group consisted of 310 infertile patients: 115 with azoospermia and 195 with oligoasthenoteratozoospermia (OAT) and a control group of 250 fertile men. We found a statistically significant difference in the genotype distribution between the two groups (chi2 = 6.315, P = 0.043). A separate analysis of azoospermic and OAT patients demonstrated that significant differences in genotype distribution were limited to the OAT group (chi2 = 7.011, P = 0.030). The presence of the D allele (DD or ID genotypes) conferred a 1.6 risk [chi2 = 6.089, P = 0.014, 95% confidence interval (95% CI) = 1.102-2.347] for male infertility in the OAT group of patients. We did not find a correlation between the I/D polymorphism genotypes and the clinical characteristics of infertile men: sperm concentration (P = 0.102), rapid progressive motility (P = 0.449), normal morphology (P = 0.085) and Johnsen score (P = 0.531). These data suggest that genetic variation in the signal peptide of the APOB gene (I/D polymorphism) might be a risk factor for the development of male infertility.  (+info)

Asthenoteratozoospermia in mice lacking testis expressed gene 18 (Tex18). (3/72)

Testis expressed gene 18 (Tex18) is a small gene with one exon of 240 bp, which is specifically expressed in male germ cells. The gene encodes for a protein of 80 amino acids with unknown domain. To investigate the function of (Tex18) gene, we generated mice with targeted disruption of the (Tex18) gene by homologous recombination. Homozygous mutant males on a mixed genetic background (C57BL/6J x 129/Sv) are fertile, while they are subfertile on the 129/Sv background, although mating is normal. We showed that Tex18(-/-) males are subfertile because of abnormal sperm morphology and reduced motility, which is called asthenoteratozoospermia, suggesting that (Tex18) affects sperm characteristics. Maturation of spermatids is unsynchronized and partially impaired in seminiferous tubules of Tex18(-/-) mice. Electron microscopical examination demonstrated abnormal structures of sperm head. In vivo experiments with sperm of Tex18(-/-) 129/Sv mice revealed that the migration of spermatozoa from the uterus into the oviduct is reduced. This result is supported by the observation that sperm motility, as determined by the computer-assisted semen analysis system, is significantly affected, compared to wild-type spermatozoa. Generation of transgenic mice containing Tex18-EGFP fusion construct revealed a high transcriptional activity of (Tex18) during spermiogenesis, a process with morphological changes of haploid germ cells and development to mature spermatozoa. These results indicate that (Tex18) is expressed predominantly during spermatid differentiation and subfertility of the male Tex18(-/-) mice on the 129/Sv background is due to the differentiation arrest, abnormal sperm morphology and reduced sperm motility.  (+info)

No evidence for an mtDNA role in sperm motility: data from complete sequencing of asthenozoospermic males. (4/72)

The first complete mitochondrial DNA (mtDNA) sequences (approximately 16,569 bp) in 20 patients with asthenozoospermia and a comparison with 23 new complete mtDNA sequences in teratoasthenozoospermic individuals, confirmed no sharing of specific polymorphisms or specific mitochondrial lineages between these individuals. This is strong evidence against the accepted claim of a major role played by mtDNA in male fertility, once supported by haplogroup association studies based on the screening of hypervariable region I. The hypothesis of maternally driven selection acting in male reproductive success must thus be treated with caution.  (+info)

Absence of tektin 4 causes asthenozoospermia and subfertility in male mice. (5/72)

Sperm flagellar motion is the outcome of a dynamic interplay between the axonemal cytoskeleton, the peri-axonemal accessory structures, and multiple regulatory networks that coordinate to produce flagellar beat and waveform. Tektins are conserved components of the flagellar proteome in evolutionarily diverse species and are believed to play essential roles in the mechanics of sperm motility. Using database mining, we identified multiple new paralogs of previously annotated tektins, including tektin 4 (TEKT4), which shares 77.1% identity with its nearest human homologue. Mouse Tekt4 is a germ cell-enriched gene, most abundantly expressed in haploid round spermatids in the testis, and the protein is localized to the sperm flagella. Male mice lacking TEKT4 on a 129S5/SvEvBrd inbred background are subfertile. Tekt4-null sperm exhibit drastically reduced forward progressive velocity and uncoordinated waveform propagation along the flagellum. In Tekt4-null sperm, flagellar ultrastructure is grossly unaltered as revealed by transmission electron microscopy. However, the ineffective flagellar strokes lead to approximately 10-fold higher consumption of intracellular ATP in Tekt4-null sperm as compared to wild-type, and null spermatozoa rapidly lose progressive motility when incubated for > or = 1.5 h. Our studies demonstrate that TEKT4 is necessary for the proper coordinated beating of the sperm flagellum and male reproductive physiology.  (+info)

Effect of cigarette smoking on semen quality of infertile men. (6/72)

INTRODUCTION: Defective sperm quality is a significant cause of infertility. It is known that cigarette smoking affects semen quality. Our aim was to compare the semen of infertile cigarette smokers with infertile non-smokers to study the effect of smoking on semen quality. METHODS: Semen samples of 100 cigarette smokers and 100 strictly non-smoking primary infertility patients were included in the study, following stringent exclusion criteria. Smokers were categorised as light, moderate and heavy smokers. Semen samples were examined for asthenozoospermia, oligozoospermia and teratozoospermia, according to World Health Organisation guidelines. RESULTS: 39 percent of non-smokers showed normozoospermia, while only three percent of smokers were normozoospermics. Light smokers predominantly showed asthenozoospermia. Heavy smokers showed asthenozoospermia, teratozoospermia and oligozoospermia. Statistical analysis using Fisher's exact test showed that the incidence of both isolated asthenozoospermia (p-value is 0.0015) and asthenozoospermia with teratozoospermia (p-value is 0.0106) among smokers was significant, in comparison to non-smokers. Overall impact of asthenozoospermia (p-value is less than 0.0001) and teratozoospermia (p-value is 0.0328) but not of oligozoospermia was observed on the semen quality in smokers, compared with non-smokers. CONCLUSION: Asthenozoospermia, the most common semen variable in our study, can be an early indicator of reduction in quality of semen, as seen in light smokers. In addition, heavy smoking produces teratozoospermia, which further reduces semen quality. Oligozoospermia may be due to factors other than smoking.  (+info)

Seminal plasma anti-Mullerian hormone level correlates with semen parameters but does not predict success of testicular sperm extraction (TESE). (7/72)

AIM: To assess seminal plasma anti-Mullerian hormone (AMH) level relationships in fertile and infertile males. METHODS: Eighty-four male cases were studied and divided into four groups: fertile normozoospermia (n = 16), oligoasthenoteratozoospermia (n = 15), obstructive azoospermia (OA) (n = 13) and non-obstructive azoospermia (NOA) (n = 40). Conventional semen analysis was done for all cases. Testicular biopsy was done with histopathology and fresh tissue examination for testicular sperm extraction (TESE) in NOA cases. NOA group was subdivided according to TESE results into unsuccessful TESE (n = 19) and successful TESE (n = 21). Seminal plasma AMH was estimated by enzyme linked immunosorbent assay (ELISA) and serum follicular stimulating hormone (FSH) was estimated in NOA cases only by radioimmunoassay (RIA). RESULTS: Mean seminal AMH was significantly higher in fertile group than in oligoasthenoteratozoospermia with significance (41.5 +/- 10.9 pmol/L vs. 30.5 +/- 10.3 pmol/L, P < 0.05). Seminal AMH was not detected in any OA patients. Seminal AMH was correlated positively with testicular volume (r = 0.329, P = 0.005), sperm count (r = 0.483, P = 0.007), sperm motility percent (r = 0.419, P = 0.021) and negatively with sperm abnormal forms percent (r = -0.413, P = 0.023). Nonsignificant correlation was evident with age (r = -0.155, P = 0.414) and plasma FSH (r = -0.014, P = 0.943). In NOA cases, seminal AMH was detectable in 23/40 cases, 14 of them were successful TESE (57.5%) and was undetectable in 17/40 cases, 10 of them were unsuccessful TESE (58.2%). CONCLUSION: Seminal plasma AMH is an absolute testicular marker being absent in all OA cases. However, seminal AMH has a poor predictability for successful testicular sperm retrieval in NOA cases.  (+info)

Superoxide dismutase and catalase activities in the seminal plasma of normozoospermic and asthenozoospermic Beagles. (8/72)

We measured the blood plasma testosterone (T) levels and superoxide dismutase (SOD) and catalase activities in the seminal plasma of the ejaculates of 5 normal (2-5 years old) and 5 asthenozoospermic (AZ-) (3-5 years old) Beagles. Sperm ejaculated by AZ-dogs was incubated for 3 hr in Eagle's MEM only (controls) or Eagle's MEM containing 100 units/ml of SOD or catalase. Sperm motility was examined during incubation. The mean (+/- SE) plasma T level of the AZ-dogs (1.2 +/- 0.2 ng/ml) was significantly lower than in the normal dogs (2.5 +/- 0.2 ng/ml) (P<0.005). The mean (+/- SE) seminal plasma SOD and catalase activities (18.8 +/- 1.9 and 0.5 +/- 0.1 unit/g protein, respectively) were significantly lower in the AZ-dogs than in the normal dog (43.3 +/- 2.5 and 2.2 +/- 0.4 unit/g protein, respectively) (P<0.001 and 0.01, respectively). The motility of sperm incubated in Eagle's MEM containing SOD or catalase was significantly higher than that of control sperm incubated in only Eagle's MEM after 2 or 3 hr of incubation (P<0.05). The results of this study indicate that poor T secretion by the testes and low antioxidant enzyme activities are related to AZ in the dog.  (+info)

The level of nerve growth factor (NGF) in the blood and seminal plasma of asthenozoospermia and oligoasthenozoospermia patients were compared to normozoospermic males and the relationship between NGF with sperm parameters and seminal antioxidant capacity were estimated to determine the role of NGF in the etiology of male infertility. Eighty-one infertile males and 40 normospermic control subjects were included in this stud. NGF levels were measured in the blood and seminal plasma, and its correlation with total antioxidant capacity (TAC), catalase (CAT) and glutathione (GSH) levels and sperm parameters were studied. There was a general trend of decreased in serum and seminal NGF concentrations of asthenozoospermic and oligoasthenozoospermic when compared to the normozoospermic samples. There was no significant association between NGF and seminal antioxidant status in asthenozoospermia and oligoasthenozoospermia males. Nevertheless, CAT positively correlated with sperm concentration, total sperm ...
There are any number of factors that can cause a problem with male fertility. Whether it is a problem with the mans sperm count, or whether he has abnormally shaped sperm, or whether he has a problem with how the sperm are moving (also known as low sperm motility), male factor fertility problems can be very frustrating things to deal with. A mans identity is, very often, wrapped up in his virility. When he as a fertility problem, it can cause a severe loss of self esteem, not to mention the frustration involved with not being able to have a baby. Knowing what can cause low sperm motility and other fertility problems for men can, however, help a man to know how to proceed with addressing the problem.. Some studies suggest, for example, that elevated levels of zinc, which may help a low sperm count, can also cause low sperm motility. While we dont know exactly what foods will and wont affect motility, eating a balanced diet can give you better health overall, which could certainly help with ...
There are any number of factors that can cause a problem with male fertility. Whether it is a problem with the mans sperm count, or whether he has abnormally shaped sperm, or whether he has a problem with how the sperm are moving (also known as low sperm motility), male factor fertility problems can be very frustrating things to deal with. A mans identity is, very often, wrapped up in his virility. When he as a fertility problem, it can cause a severe loss of self esteem, not to mention the frustration involved with not being able to have a baby. Knowing what can cause low sperm motility and other fertility problems for men can, however, help a man to know how to proceed with addressing the problem.. Some studies suggest, for example, that elevated levels of zinc, which may help a low sperm count, can also cause low sperm motility. While we dont know exactly what foods will and wont affect motility, eating a balanced diet can give you better health overall, which could certainly help with ...
Publisher: Foundation for Cellular and Molecular Medicine. Date Issued: 2016-08-25. Abstract: Prohibitin (PHB), a major mitochondrial membrane protein, has been shown earlier in our laboratoryto regulate sperm motility via an alteration in mitochondrial membrane potential (MMP) in infertile men with poor sperm quality. To test if PHB expression is associated with sperm mitochondrial superoxide (mROS) levels, here we examined sperm mROS levels, high MMP and lipid peroxidation in infertile men with poor sperm motility (asthenospermia, A) and/or low sperm concentrations (oligoasthenospermia, OA). The diaphorase-type activity of sperm mitochondrial complex I (MCI) and PHB expression were also determined. We demonstrate that mROS and lipid peroxidation levels are significantly higher in sperm from A and OA subjects than in normospermic subjects, whereas high MMP and PHB expression are significantly lower. A positive correlation between mROS and lipid peroxidation and a negative correlation of mROS ...
HIBADH Polyclonal Antibody from Invitrogen for Western Blot and Immunohistochemistry (Paraffin) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 100 µL purified antibody (1.01 mg/ml) in 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7.
Okay, so my boyfriend got a sperm count in October and was devastated with the news that it was only 4 million. I figured that it was because we didnt abstain long enough, but needless to say, our doctor was pushing IVF with ICSI. Anyways, after we searched long and hard online we came across this site...ordered Fertilaid For Men and took for only 1.5 weeks and went in for another sperm analysis....85 million / cc!! We still have an IUI appointment for my next cycle. This morning we woke up, were on our way to work and I started feeling nauseous, however I have severe acid reflux and just attributed it to that. Normally, acid comes up and Im good within 20 minutes and get on with my day, but this wouldnt go away. I had "spinny" head, and started having hot sweats, so I said we have to go home. Went home, passed out all day, and woke up feeling very hot and sweaty -- low grade fever. I woke up, ate Chinese with the family, went to the bathroom to check and see if there was any discharge and lo ...
Atshan M, et al. - Semen samples were collected from 31 infertile men with immotile short-tail sperm (ISTS) as case group and 31 normozoospermic men as a con...
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Male infertility is a multifactorial disorder with impressively genetic basis; besides, sperm abnormalities are the cause of numerous cases of male infertility. In this study, we evaluated the genetic variants in exons 4 and 5 and their intron-exon boundaries in RABL2B gene in infertile men with oligoasthenoteratozoospermia (OAT) and immotile short tail sperm (ISTS) defects to define if there is any association between these variants and human male infertility.
... , Virendra Sehgal N, Naresh Sehgal, Ruchi Sehgal, Deepa Sehgal, a
1. Coppola S, Buccoliero G, Laddago V et al: Topical thymopentin therapy in HIV positive patients with recurrent oral candidiasis: a pilot study. Microbiologica 1996; 19(4):351-356. 2. Zivanovic A, Arsenijevic S, Ristic P et al: Treatment of asthenozoospermic men with Thymex-L. J Thymol 1996; 4:390-393. 3. Crisan M, Stugran C, Gal O et al: In vivo effects of thymic hormones (Imunotim) on immunologic parameters of patients with secondary immunodeficiency diseases. Roum Arch Microbiol Immunol 1992; 51(4): 213-224. 4. Dworniak D, Tchorzewski H, Pokoca L et al: Treatment with thymic extract TFX for chronic active hepatitis B. Archiv Immunol Ther Exper 1991; 39(5/6):537-547. 5. Zeman K, Dworniak D, Tchorzewski H et al: Effect of thymic extract on allogeneic MLR and mitogen-induced responses in patients with chronic hepatitis B. Immun Invest 1991; 20(7):545-555. 6. Corradi G, Cappellari A, Pomari R et al: Morphometric analysis of peritumoral lymph nodes in patients operated on for uterine cancer, ...
A lot of people often joke around about someone having low sperm count. Then again, what these people are not aware of is that the condition of having a very low sperm count is not laughing matter at all. A low sperm level can mean a lot of things. Again, ones sperm levels are connected with his overall health, thus the matter ought to be taken seriously and given immediate action.. When is Sperm Count Low?. A low sperm level is the most typical infertility issue for males. Generally speaking, ones sperm count is measured based on the ratio of sperm thats ejaculated per milliliter of semen. Normal levels are usually around 40-300 million per semen millileter. Thus, a low sperm level is one thats below 20 million.. The Causes of Low Sperm Levels. A low sperm count can be brought about by a variety of factors. It could be genetic; it could possibly be caused by environmental elements, etc. The low levels might be brought on due to too much stress, or in most cases, certain nutritional ...
Most common causes of infertility in men are explained in this article. An exact cause is not known in some cases (known as unexplained infertility).. Sperm Disorders. There are four types of sperm disorders: low sperm count known as Oligospermia, complete absence of sperm cells referred to as Azoospermia, poor sperm motility known as Asthenospermia (inability of the sperm to move fast enough or to move in a straight line) and abnormal sperm morphology referred to as Teratospermia (abnormally shaped sperm). All these conditions interfere with a sperms ability to reach and fertilize an egg and are regarded as major causes of infertility in men.. Sperm disorders are results of: birth defects, hormone deficiency in the pituitary gland or hypothalamus, aging, exposure to harmful substances, radiations or high temperature, chemotherapy, sexually transmitted diseases and other lifestyle factors such as smoking, alcohol abuse, use of marijuana or cocaine, excessive exercise, bike riding, stress ...
Objective - To determine if people receiving opioid agonist treatment (OAT), a long-term treatment approach, are also receiving high-quality primary care.. Design - Retrospective cohort study.. Setting - Ontario.. Participants - Recipients of public drug benefits who had at least 6 months of continuous use of methadone or buprenorphine between October 1, 2012, and September 30, 2013.. Main Outcome Measures - Rates of cancer screening and diabetes monitoring among those who had at least 6 months of continuous OAT were compared with matched controls. Conditional logistic regression models were used to assess differences after adjusting for confounders. In secondary analyses, outcomes by type of OAT and factors related to health care delivery were compared.. Results - A cohort of 20 406 OAT patients was identified; they had a mean (SD) of 31 (15) physician clinic visits during the 6-month study period. Compared with the control group, OAT patients were less likely to receive screening for cervical ...
Improving sperm motility naturally through nutrient supplementation is possible because low sperm motility is a sign of increased oxidative stress in the body.
Teratozoospermia Definition - Teratozoospermia is a condition where there are a large number of misshapen sperm found in a mans semen. Normal sperm...
Having a low sperm count doesnt mean you cant get your partner pregnant -- but it can make it a lot more difficult. Low sperm count happens for a variety of reasons but, great news, you can improve how much sperm you produce.
This article explained what are the different symptoms and reasons for low sperm count.For Infertility or Low sperm count symptoms and reasons must be pointed out in order to cure it.
The Mayo Clinic confirms that a successful pregnancy remains possible for men with low sperm counts. Men with low sperm counts can increase their odds of fertilization by engaging in an increased...
There are many possible reasons for a low sperm count. A basic question for your husband is whether or not this is a new problem. Has he previously fa
Build: Sat Feb 17 08:59:16 EST 2018 (commit: 16064c5). National Center for Advancing Translational Sciences (NCATS), 6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-435-0888. ...
Hi ladies! I know that I dont post in here much (sorry!) but I have just gotten some more bad news and was looking for help. My DHs Sperm DNA Fragmentation has come back quite high at 30%, and I have been googling a lot and found - page 59
I am a bit surprised how could I get my first child with only 2 months try. If someone have fathered before will he have any issues to have another child? Please let me know how bad is the report and what are my options ...
Complete information for TCTE1 gene (Protein Coding), T-Complex-Associated-Testis-Expressed 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
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I have being married to my wife for the past 3 years and 9 months we have obviously being living fine for those past few years. but the problem i was having was that i havent being able to impregnate her because i thought i had a low sperm count,i had being visiting many hospital done various of test and samples but to no avail because all they could tell me was that am perfectly fine but i know that i am not fine my wife has being becoming impatient because i havent being able to impregnate her after so many years. Things got worst each day, every seconds of my life i always think of what next to do because am being fed of me being incapable. i have come across so many health attendant who normally tell me that i have no problem. but i know that am sincerely not OK. One faithful evening when i came online in search of some people testified that he brought their Ex lover back, some testified that he restores womb, cure cancer, and other sickness, some testified that he can cast a spell to stop ...
I have being married to my wife for the past 3 years and 9 months we have obviously being living fine for those past few years. but the problem i was having was that i havent being able to impregnate her because i thought i had a low sperm count,i had being visiting many hospital done various of test and samples but to no avail because all they could tell me was that am perfectly fine but i know that i am not fine my wife has being becoming impatient because i havent being able to impregnate her after so many years. Things got worst each day, every seconds of my life i always think of what next to do because am being fed of me being incapable. i have come across so many health attendant who normally tell me that i have no problem. but i know that am sincerely not OK. One faithful evening when i came online in search of some people testified that he brought their Ex lover back, some testified that he restores womb, cure cancer, and other sickness, some testified that he can cast a spell to stop ...
Venturing into an emerging environmental frontier, a group of experts meets in Baltimore this week to figure out how to test thousands of man-made chemicals for whether they may cause low sperm
Atrophy of semeniferous tubules (this is wherever sperm is manufactured). So how just does consuming attain this?. Liquor plays a part in accumulation of girls hormones and prolactin and depletes zinc plus folic acid. The top secret nutrients needed for optimum fertility and too a much healthier infant.. Sperm are prone to injuries due to the fact of alcohol usage, unsafe medicines, smoking cigarettes cigarettes, very poor diet along with other environmental harmful toxins for 116 days ahead of development.. What this indicates is that all you eat and take uncovered to in one hundred sixteen days just before ejaculation has influenced the Substantial high quality and range of that specific batch of your seminal fluid. Consequently the one hundred 20 day pre conceiving interest program to make it simpler to as well as your lover increase you egg cell plus sperm well being.. Males element infertility, reduced sperm motility and lower sperm count might be effectively handled with positive dietary ...
Anovulatory infertility, cryptorchidism, male hypogonadism, corpus luteum insufficiency, oligospermia, hypogonadotropic hypogonadism, habitual abortion, asthenospermia ...
The main cause of male infertility is low sperm count. Many biological and environmental factors can cause low sperm count in men. The causes of male infertility have been explained in texts of ayurveda.
The microtubule (MT)‐severing enzyme katanin triggers dynamic reorientation of cortical MT arrays that play crucial functions during plant cell morphogenesis, such as cell elongation, cell wall biosynthesis, and hormonal signaling. MT severing specifically occurs at crossover or branching nucleation sites in living Arabidopsis cells. This differs from the random severing observed along the entire length of single MTs in vitro and strongly suggests that a precise control mechanism must exist in vivo. However, how katanin senses and cleaves at MT crossover and branching nucleation sites in vivo has remained unknown. Here, we show that the katanin p80 subunit KTN80 confers precision to MT severing by specific targeting of the katanin p60 subunit KTN1 to MT cleavage sites and that KTN1 is required for oligomerization of functional KTN80-KTN1 complexes that catalyze severing. Moreover, our findings suggest that the katanin complex in Arabidopsis is composed of a hexamer of KTN1-KTN80 heterodimers ...
35 yrs old Male asked about Low sperm count, 1 doctor answered this and 139 people found it useful. Get your query answered 24*7 only on | Practo Consult
The growth of sperm in our body is a major benefit of testosterone. Questions like "is nugenix a scam?" are commonly asked by most of the men that are looking to use the top testosterone boosters but have you ever thought that whether these supplements are actually good for your body or not. Most of the people dont even think of conducting any research about these supplements because their friends recommend them to use these supplements while expressing the amazing benefits they have gained from them.. An intelligent person never relies on such references and he always tries to find all the important information about something that someone is recommending him to use. If you are suffering from low sperm count problem and a friend has recommended you to use the testosterone boosters, then you must read the following information very carefully.. ...
In this article, James M. Hotaling, MD, MS, outlines the elements that comprise a cost-effective workup of the infertile male patient.
Male infertility could be due to various factors or disorders. To treat male infertility these factors are to be analysed and then successfully treated.Here are some options to treat male infertility.
Katnal2 - Katnal2 (Myc-DDK-tagged) - Mouse katanin p60 subunit A-like 2 (cDNA clone MGC:78332 IMAGE:30146310) available for purchase from OriGene - Your Gene Company.
A low sperm count (scientifically referred to as oligospermia) is when the semen you ejaculate during an orgasm contains fewer sperm than is considered normal. The World Health Organization defines a low sperm count as less than 20 million sperm per milliliter of semen.
Hi I am 28 and my husband is 27 and we live in Notts. We have been ttc no 1 since Oct 08. Have very irregular cycles and hubby has a low sperm motility. Got BFP in Nov 09 but sadly had a mmc in Jan 10 at 11 weeks. First month ttc since and hoping it wont take so long again!! Got first BFP after making a few changes so doing the same things again! Hubby back on vits, brazil nuts, loose underwear and low alcohol intake. I am taking santogen vits and evening primrose oil (which I only took for the first time the month we got our BFP). Also turned CBFM on and using zestica! Who would have thought it could get so complicated when all I have to do is relax ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Question - Suggest me the treatment for low sperm count and motility.. Ask a Doctor about diagnosis, treatment and medication for Tuberculosis, Ask an Infertility Specialist
Its a contentious issue but every now and then fluoride rears its ugly head again. Now it looks like this useless chemical can affect male fertility.
Question - Can having no children increase my body weight suddenly ?. Ask a Doctor about diagnosis, treatment and medication for Low sperm count, Ask an Infertility Specialist
My husaband is 31 year old, he has got low sperm count problem Doctor has suggested him Productive M tablets are these tablets really beneficaial and how long should he continue with these tablets
If an AZ goes down, PersistentVolumes (PVs) and their data also go down and cannot be automatically re-attached. To preserve your PV data in the event of a fallen AZ, your persistent workload needs to have a failover mechanism in place.. Depending on the underlying storage type, PVs are either completely free of zonal information or can have multiple AZ labels attached. Both options enable a PV to travel between AZs.. To ensure the uptime of your PVs during a cluster upgrade, VMware recommends that you have at least two nodes per AZ. By configuring your workload as suggested, Kubernetes reschedules pods in the other node of the same AZ while BOSH is performing the upgrade.. For information about configuring PVs in Enterprise PKS, see Configuring and Using PersistentVolumes.. For information about the supported storage topologies for Enterprise PKS on vSphere, see PersistentVolume Storage Options on vSphere.. ...
398 #define TEX_FLAG_MASK ( TEX_COLORBAND , TEX_FLIPBLEND , TEX_NEGALPHA , TEX_CHECKER_ODD , TEX_CHECKER_EVEN , TEX_PRV_ALPHA , TEX_PRV_NOR , TEX_REPEAT_XMIR , TEX_REPEAT_YMIR ...
What will urologists do for low sperm count - What will urologists do for low sperm count? Testing sperm. A semen analysis, count, motility and volume, detailed morphology. Other tests may be helpful. An exam of the penis, testes, sperm collecting systems, and prostate are indicated. Examination for hernia or varicocoele.
Join our community. Maxocum improve semen quality, fertility and motility naturally. Safe herbal formula. What causes low sperm count in maleHow to Increase Your Sperm Count (with Pictures) - wikiHow.
The purpose of this study was to analyze whether the anogenital distance (AGD) was associated with variability in semen parameters. Semen parameters analyzed following the WHO guidelines and sperm DNA fragmentation were evaluated in 160 semen samples obtained over a period of a year from 16 healthy male volunteers. Two types of AGD measurements from the anus to the rear base of the scrotum (AGDAS) and to the cephalic insertion of the penis (AGDAP) were taken in each individual. The association between AGDs and semen parameters were studied using three statistical tools: a) general coefficient of variation (CV) and intra-individual coefficient of variation (CVi), b) general linear models for repeated measures, and c) mixed model fixed effects panel data ...
I have just been reading through the intros again and quite cant believe how many of us have husbands with low sperm counts or poor motility. Has anyone got any ideas why this is such a regular occurrence these days? I have been told that there is too much oestregen in the water!!! ,br,,br,I thought maybe my husband had had some side effect from having Gulf War injections as he has never smoked, hardly drinks, wears loose pants(I know way too much info), takes showers not baths. But then I see hes not on his own. At least it doesnt knock their masculinity when so many others are the same!!! Even though they dont like to talk about it like us girls. ,br,,br,What else can we do to make these little fishes swim better? I have started making him take folic acid and zinc tablets just to see if this will improve the little blighters.,br,,br,If anyone has any words of wisdom to share Id like to listen as Im sure would others in the same boat.,br,,br,Lisa (Loonpants ...
Hi, First, I´d like to congratulate the authors for such a good work. I think that in this type of clinical studies it is important that researchers report their findings even if they didn´t see significant differences among compared groups.. I´d also like to ask the authors what do they think about the use of the methylated DNA quantification kit (Sigma) that they used compared with the Infinium HumanMethylation450 BeadChip (Illumina). Since in my group we are also interested in the study of global methylation patterns, author´s comments would be more than welcome.. Thanks.. ...
Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
The inability to procreate affects both men and women. Male infertility contributes to as much as 50% of fertility issues for couples.
The sperm DNA fragmentation involves damage in the genetic material of sperm. At Institut Marquès we analyze and treat all causes.
As a mans sperm production declines, so does the proportion of sperm bearing the Y chromosome, thus decreasing the likelihood of siring a son.
Can hemorrhoids affect male potency? Hemorrhoidal nodes are painful, unpleasant, problematic, and, of course, the very location of the damaged veins makes me think that its also a shame. But
Sigma-Aldrich offers abstracts and full-text articles by [D Trisciuoglio, M Desideri, V Farini, T De Luca, M Di Martile, M G Tupone, A Urbani, S DAguanno, D Del Bufalo].
Low sperm count is a condition called oligospermia. This is the term used to describe the condition when the sperm count is low, less than 15 million sperm/ml. The average man can produce this many sperm multiple times per day. If there are no sperm at all in a semen sample, the condition is termed azoospermia. When you are trying to have children, the number of sperm a man ejaculates is quite important. Having a low sperm count decreases the odds that one of your sperm will fertilize your partners egg, resulting in pregnancy. Nonetheless, many men who have a low sperm count are still able to father a child. Sometimes it is necessary for Artificial Reproductive Technology like IUI or IVF to be utilized, but whether a couple is Trying To Conceive Naturally or preparing for an IUI or IVF cycle, low sperm counts can be improved to increase the likelihood of a successful and healthy pregnancy.. There are many potential causes for low sperm count. In some cases, an underlying problem such as an ...
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3-D ultrasound, abortifacient, acquired immunodeficiency syndrome, adrenal gland disorders, AFP test, AIDS, alcohol-related birth defects, alcohol-related neurodevelopmental disorder, alpha-fetoprotein test, amniocentesis, anemia, anovulation, ARBD, ARND, artificial insemination, asthenospermia, asthma, autoimmune disorders, birth control pills, birth defects, breech birth, breech presentation, cervical dilator, cervical stenosis, cervix, chlamydia, chorionic gonadotropin, chorionic villi sampling, cleft lip, cleft palate, condom, cone biopsy, Crohns disease, Cushings syndrome, CVS, cystic fibrosis, DES, diabetes, diabetes mellitus, diethylstilbesterol, Doppler ultrasound, Downs syndrome, duodenal atresia, ectopic pregnancy, egg, embryonal stage, emergency contraceptive pill, endometriosis, epilepsy, estriol, FAS, fertility, fertilization, fetal Alcohol Syndrome, fetal echocardiography, fetal stage, fetus, first trimester, flu shots, fluoride, gastrointestinal disorders, genital warts, ...
3-D ultrasound, abortifacient, acquired immunodeficiency syndrome, adrenal gland disorders, AFP test, AIDS, alcohol-related birth defects, alcohol-related neurodevelopmental disorder, alpha-fetoprotein test, amniocentesis, anemia, anovulation, ARBD, ARND, artificial insemination, asthenospermia, asthma, autoimmune disorders, birth control pills, birth defects, breech birth, breech presentation, cervical dilator, cervical stenosis, cervix, chlamydia, chorionic gonadotropin, chorionic villi sampling, cleft lip, cleft palate, condom, cone biopsy, Crohns disease, Cushings syndrome, CVS, cystic fibrosis, DES, diabetes, diabetes mellitus, diethylstilbesterol, Doppler ultrasound, Downs syndrome, duodenal atresia, ectopic pregnancy, egg, embryonal stage, emergency contraceptive pill, endometriosis, epilepsy, estriol, FAS, fertility, fertilization, fetal Alcohol Syndrome, fetal echocardiography, fetal stage, fetus, first trimester, flu shots, fluoride, gastrointestinal disorders, genital warts, ...
3-D ultrasound, abortifacient, acquired immunodeficiency syndrome, adrenal gland disorders, AFP test, AIDS, alcohol-related birth defects, alcohol-related neurodevelopmental disorder, alpha-fetoprotein test, amniocentesis, anemia, anovulation, ARBD, ARND, artificial insemination, asthenospermia, asthma, autoimmune disorders, birth control pills, birth defects, breech birth, breech presentation, cervical dilator, cervical stenosis, cervix, chlamydia, chorionic gonadotropin, chorionic villi sampling, cleft lip, cleft palate, condom, cone biopsy, Crohns disease, Cushings syndrome, CVS, cystic fibrosis, DES, diabetes, diabetes mellitus, diethylstilbesterol, Doppler ultrasound, Downs syndrome, duodenal atresia, ectopic pregnancy, egg, embryonal stage, emergency contraceptive pill, endometriosis, epilepsy, estriol, FAS, fertility, fertilization, fetal Alcohol Syndrome, fetal echocardiography, fetal stage, fetus, first trimester, flu shots, fluoride, gastrointestinal disorders, genital warts, ...
Low sperm count. Find out about the causes and modern methods of male infertility treatment: Sperm washing, surgical sperm retrieval, assisted reproductive techniques in Germany.
The purpose of this study was to analyze whether the anogenital distance (AGD) was associated with variability in semen parameters. Semen parameters analyzed following the WHO guidelines and sperm DNA fragmentation were evaluated in 160 semen samples obtained over a period of a year from 16 healthy male volunteers. Two types of AGD measurements from the anus to the rear base of the scrotum (AGDAS) and to the cephalic insertion of the penis (AGDAP) were taken in each individual. The association between AGDs and semen parameters were studied using three statistical tools: a) general coefficient of variation (CV) and intra-individual coefficient of variation (CVi), b) general linear models for repeated measures, and c) mixed model fixed effects panel data ...
I have made semen analyst and the progressive motility was 25%, The not progressive motility was 15%, middling progressive motility was 5%, low progressive motility was 5% and the not motility is 50% and the PH was 8, so does this normal
Low sperm count is among the sure-shot signs of infertility in men because if the sperms are not sufficient it will not help the egg to fertilise into an embryo. You cant ascertain this at home, but if you have been having unprotected intercourse for about a year and still trying to have a baby, then you are suggested to take a test to ensure your sperm count isnt poor. Typically any lesser than 15 million sperm per millilitre of semen is a low sperm count. It ideally should hover between 20 and 150 million sperm per millilitre of semen. There are several factors that can be attributed to a lowered sperm count such as chemical exposure, an imbalance of hormones and infection in the testicles. Sooner you see your doctor, the better. ...
Sigma-Aldrich offers abstracts and full-text articles by [Marie Lagouge, Arnaud Mourier, Hyun Ju Lee, Henrik Spåhr, Timothy Wai, Christian Kukat, Eduardo Silva Ramos, Elisa Motori, Jakob D Busch, Stefan Siira, Elisabeth Kremmer, Aleksandra Filipovska, Nils-Göran Larsson].
... ! Generic Clomid is an effective medication which helps women to get pregnant and men with fertility problems in the result of low sperm counts. Generic Clomid acts by stimulating ovulation.
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Our team in Birmingham has shown that sperm DNA damage more than doubles the risk of miscarriage.. This is a crucial finding; until now, miscarriage has generally been considered an exclusively female problem, with investigations and management targeting only women.. Yet the role of sperm DNA damage in miscarriage is not surprising. This is because while most cell types are able to repair damaged DNA, sperm lose this ability during development and have to rely on repair mechanisms in the egg. As the level of damage in the sperm DNA increases it also becomes increasingly likely that any repairs by the egg may create genetic mutations that could increase the risk of miscarriage.. Most existing tests for sperm DNA damage are insufficiently sensitive to be clinically useful; we are developing a more accurate combined assay system and therapies to achieve repair. One potential cause of sperm DNA damage is exposure to Reactive Oxygen Species (ROS) during production and transit. We are investigating ...
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Submission: There are two things of interest in this paper. First is confirmation that even in women with normal ovarian reserve, elevated sperm DNA fragmentation (SDF) is related to increased rates of miscarriage. It seems that clinics who do NOT carry out an SDF test and treatment results in miscarriage may be exposing themselves to complaint. Unfortunately, in this study, IVF and ICSI produced the same outcomes. The authors identified a SDF level of 27% as the critical cutoff point. However the main feature of the article was that the SDF level significantly influenced the rate that live birth rates were diminished in women with decreased ovarian reserve. That is, when addressing the problem of age related success rates, the degree of male related sperm damage needs to be also considered. The authors suggested this may be interpreted as an indication that poor oocyte quality may be unable to correct the sperm DNA damage. While the concept of oocyte restoration of sperm quality as been around ...
Here we describe a rare case of an apparently balanced karyotype of 46, XY, t(1;22;4)(p22.3;q11.1;q31.1) in a infertile male with oligoastenoteratozoospermia (OAT). He was the second patient with complex chromosomal rearrangement (CCR) referred to ou
My fiance and I have been thinking about trying to conceive a baby. When he ejaculates, his sperm is almost like water. Its still white colored, but its runny. Does this mean he could be infertile, or that he has a low sperm count? And if so, what are the options for treatment ...
TPC, please i made the worst mistake of my life by masturbating for several months.By Gods grace i have been saved and i masturbate no more;but i am experiencing a lighter,watery,less sticky and less slippery semen on nocturnal emissions.I am afraid these may be signs of low sperm count.Assuming it is so,please would it be to advisable to get on drugs which have the capacity to treat these symptoms?. ...
Im a 29 male, i have severe low sperm count and motility but all other readings are good except for the RBCs and WBCs count which is my question. I have made many tests and undergone varicoselectomy be...
Having a low sperm count can be frustrating if you and your partner are trying to conceive. Taking certain steps to improve your health and taking specific...
Weve been together for almost five years and TTC for much of the last two. Weve been through several unsuccessful Clomid cycles, sat out lots of months with cysts, and went for our first IUI in February. We were cancelled because of a low sperm count and found out IVF with ICSI is pretty much our only shot. After lots of testing and a surgery, we are in the midst of our IVF cycle right now. Tomorrow is transfer day ...
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Hello list, I uploaded to CTAN platex and uplatex at the same time (on Nov29), but only platex was updated in TeX Live on that day, and uplatex is not yet. Do you have some problem with uplatex? If so, please let me know. Best, Hironobu Yamashita ...
Prothrombin time (PT) is the leading test for monitoring oral anticoagulation therapy (OAT). We sought to determine INR taking into account only active coagulation factors FII, FVII and FX without inhibition in patient plasmas and calibrator kits.. We measured PT using a combined thromboplastin reagent. The calculation was based on a new PT method, which measures active coagulation factors (F II, F VII, FX) and corrects the errors caused by inactive coagulation factors.. On this basis, an INR result with and without inhibition for individual patient samples was also calculated and applied to 200 plasma samples obtained from OAT patients. Conspicuous variation in inhibition between the four calibration kits was noted. The kinetics of this inhibition was closest to a noncompetitive pattern.. The need of correction for INRs of single patients increases with higher INRs. At the same level of patient INRs the coagulation inhibiton varies markedly.. It has been known that different thromboplastin ...
... : Male reproductive physiology, Diagnosis of Male Infertility, Causes of Male infertility, Treatment of Male infertility, Male Infertility Clinical Findings
Effects of some beta-adrenergic blockers on male fertility parameters in rats.: The effects of atenolol (9 and 18 mg/kg.b.wt.), metoprolol (3.5 and 7 mg/kg.b.wt
SEMEN ANALYSIS TOTAL SPERM COUNT - 14 MILLION/C.C GOOD - 39% MODERATE - 41% NON-MOTILE- 20% ABNORMAL FORMS - 15% PREMATURE FORMS- 4% PUS CELL -
Oligozoospermia treatment. Efficient treatment of male sterility in Germany: modern conservative and surgical techniques to treat low sperm count.
FertilHerb® for Men is an all natural male fertility supplement, developed to maximize mascular fertility. FertilHerbs components have been studied extensively and showed a significant improvement in parameters of sperm motility, concentration, and shape for men with low sperm count.
Low sperm count? Learn why male fertility isnt simply a matter of being sub-fertile or not with diagnosis and effective custom treatment at Sustain Health.
A wide range of physical and emotional factors can cause infertility. Infertility may be due to problems in the woman, man, or both.. Male infertility may be due to:. ...
Female along with male infertility is a common subject in the modern era. If you feel that you and your partner have a problem in having a child, then you need to have a clear-cut idea about male as well as female infertility.
I am a 29 years old man having |b|low sperm production |/b|. If I have intercourse thrice in a day, then there is almost zero quantity of semen the third time. Even at the first time semen quantity is very less. How can I increase my semen production?
... Ali M. A. Hassan, Atef F. El Hadad, Abd El Shakour A.H. El-Mohammady, Olfat G. Shaker, Magdy E...
... Ali M. A. Hassan, Atef F. El Hadad, Abd El Shakour A.H. El-Mohammady, Olfat G. Shaker, Magdy E...
Male infertility means that a man has a problem with his reproductive system. It means he cant start a pregnancy with a female partner. Read on to learn about causes, diagnosis, and treatment.
... means that a man has a problem with his reproductive system. It means he cant start a pregnancy with a female partner. Read on to learn about causes, diagnosis, and treatment.
Interested in know why male infertility problems increasing day by day? If, yes then you need to follow this post and read the full details.
So at my last visit with the RE he said he is confident we can get pregnant with our low sperm count with a medicated IUI (Clomid for me + the HCG trigger shot), but that the more aggressive (quicker) way to go about it would be to do an IUI with injectables and the…
You are over 35 years old and trying to conceive for some time but it is not happening, there are many possible reasons, ranging from ovulation irregularities, problems in your reproductive system, low sperm count of your spouse, or an underlying medical problem.. Believe it or not, one of the possible reasons you are not conceiving could be that you are not trying enough or not trying long enough. Think about it - how long have you been trying? It may feel like youve been trying forever and maybe you have, but its important to know that many couples wont conceive right away.. In this piece written for Punch, fertility specialist, Dr. Abayomi Ajayi gets into the details, read on: Actually about 4 in 5 couples conceive after six months of trying. Approximately 90 per cent will be pregnant after 12 months of trying to get pregnant, assuming that you have well-timed intercourse every month.. READ ALSO: Fertility Consultant, Prof. Oladapo Ashiru On How IVF Can Help Couples Eliminate The Risk Of ...
Can TeXworks respond to lines such as the following: %!TEX root =../FOO/\jobname.tex Please note the use of \jobname which would need to have been specially taken care of. And, unfortunately, I am no programmer and thus unable to check the code for myself. I am a completely satisfied user of TeXShop and am inquiring in consideration of the windows users of my stuff which uses this line systematically. Hopeful regards --schremmer ...
How To Increase Sperm Count. Low sperm count refers to an unhealthy condition that some men experience when they do not have appreciable amount of sperm cells in their semen. Semen is a white or grey liquid, but can occasionally appear yellowish. Pink or red semen suggests that blood is present. Although this is only rarely due to a serious health problem. Low sperm count and infertility in men is more prevalent than most couples think. People tend to think that if a woman is not getting pregnant the fertility issue must be with the woman.. Usually, each milliliter of semen contains millions of spermatozoa (sperm), but the majority of the volume consists of secretions of the glands in the male reproductive organs. Low sperm count is one of the leading causes of infertility in men. Gem and if you are thin so you could have a child in trouble. The purpose of semen is purely for reproduction, as a vehicle to carry the spermatozoa into the female reproductive tract. Having a low sperm count ...
"Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia". Hum. Reprod. 23 (8): 1957-62. doi: ... with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male ...
In mice, a deletion on mtDNA causes oligospermia and asthenozoospermia, resulting in infertility. Taken together, mtDNA ...
... is a combination of: Asthenozoospermia (reduced sperm motility) and Oligozoospermia (low spermatozoon ...
"Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene". ...
Haplogroup T can predispose to asthenozoospermia (Ruiz-Pesini 2000). However, these findings have been disputed due to a small ...
Very low sperm count Asthenozoospermia: poor sperm motility Teratozoospermia: sperm carry more morphological defects than usual ...
... increase in sperm with abnormal morphology Asthenozoospermia - reduced sperm motility There are various combinations of these ...
... (or asthenospermia) is the medical term for reduced sperm motility. Complete asthenozoospermia, that is, 100 ... asthenozoospermia) than in men with oligozoospermia or teratozoospermia. Among men with asthenozoospermia, 31% were found to ... Causes of complete asthenozoospermia include metabolic deficiencies, ultrastructural abnormalities of the sperm flagellum (see ... Ortega, C.; Verheyen, G.; Raick, D.; Camus, M.; Devroey, P.; Tournaye, H. (2011). "Absolute asthenozoospermia and ICSI: What ...
It can also be caused by a retroperitoneal lymph node dissection for testicular cancer if nerve pathways to the bladder sphincter are damaged, with the resulting retrograde ejaculation being either temporary or permanent. Modern nerve-sparing techniques seek to reduce this risk; however, it may also occur as the result of Green Light Laser prostate surgery. Surgery on the bladder neck accounted for about ten percent of the cases of retrograde ejaculation or anejaculation reported in a literature review.[4] Retrograde ejaculation is a common side effect of medications, such as tamsulosin,[5] that are used to relax the muscles of the urinary tract, treating conditions such as benign prostatic hyperplasia. By relaxing the bladder sphincter muscle, the likelihood of retrograde ejaculation is increased. The medications that mostly cause it are antidepressant and antipsychotic medication, as well as NRIs such as atomoxetine; patients experiencing this phenomenon tend to quit the medications.[6][7] ...
Boreoeutherian land mammals, the large group of mammals that includes humans, have externalized testes.[32] Their testes function best at temperatures lower than their core body temperature. Their testes are located outside of the body, suspended by the spermatic cord within the scrotum.. There are several hypotheses why most boreotherian mammals have external testes which operate best at a temperature that is slightly less than the core body temperature, e.g. that it is stuck with enzymes evolved in a colder temperature due to external testes evolving for different reasons, that the lower temperature of the testes simply is more efficient for sperm production.. 1) More efficient. The classic hypothesis is that cooler temperature of the testes allows for more efficient fertile spermatogenesis. In other words, there are no possible enzymes operating at normal core body temperature that are as efficient as the ones evolved, at least none appearing in our evolution so far.. The early mammals had ...
In both the acute and chronic forms, antibiotics are used if an infection is suspected. The treatment of choice is often azithromycin and cefixime to cover both gonorrhoeae and chlamydia. Fluoroquinolones are no longer recommended due to widespread resistance of gonorrhoeae to this class.[7] Doxycycline may be used as an alternative to azithromycin. In chronic epididymitis, a four- to six-week course of antibiotics may be prescribed to ensure the complete eradication of any possible bacterial cause, especially the various chlamydiae. For cases caused by enteric organisms (such as E. coli), ofloxacin or levofloxacin are recommended.[7] In children, fluoroquinolones and doxycycline are best avoided. Since bacteria that cause urinary tract infections are often the cause of epididymitis in children, co-trimoxazole or suited penicillins (for example, cephalexin) can be used. Household remedies such as elevation of the scrotum and cold compresses applied regularly to the scrotum may relieve the pain ...
A certain degree of curvature of the penis is considered normal, as many men are born with this benign condition, commonly referred to as congenital curvature. The disease may cause pain; hardened, big, cord-like lesions (scar tissue known as "plaques"); or abnormal curvature of the penis when erect due to chronic inflammation of the tunica albuginea (CITA).[citation needed] Although the popular conception of Peyronie's disease is that it always involves curvature of the penis, the scar tissue sometimes causes divots or indentations rather than curvature. The condition may also make sexual intercourse painful and/or difficult, though it is unclear whether some men report satisfactory or unsatisfactory intercourse in spite of the disorder.[citation needed] It can affect men of any race and age. The disorder is confined to the penis, although a substantial number of men with Peyronie's exhibit concurrent connective tissue disorders in the hand, and to a lesser degree, in the feet. About 30 percent ...
Most experts consider androgens (testosterone and related hormones) to play a permissive role in the development of BPH. This means that androgens must be present for BPH to occur, but do not necessarily directly cause the condition. This is supported by evidence suggesting that castrated boys do not develop BPH when they age. In an unusual study of 26 eunuchs from the palace of the Qing dynasty still living in Beijing in 1960, the prostate could not be felt in 81% of the studied eunuchs.[14] The average time since castration was 54 years (range, 41-65 years). On the other hand, some studies suggest that administering exogenous testosterone is not associated with a significant increase in the risk of BPH symptoms, so the role of testosterone in prostate cancer and BPH is still unclear. Further randomized controlled trials with more participants are needed to quantify any risk of giving exogenous testosterone.[15] Dihydrotestosterone (DHT), a metabolite of testosterone, is a critical mediator of ...
Prostate cancer is classified as an adenocarcinoma, or glandular cancer, that begins when normal semen-secreting prostate gland cells mutate into cancer cells. The region of prostate gland where the adenocarcinoma is most common is the peripheral zone. Initially, small clumps of cancer cells remain confined to otherwise normal prostate glands, a condition known as carcinoma in situ or prostatic intraepithelial neoplasia (PIN). Although there is no proof that PIN is a cancer precursor, it is closely associated with cancer. Over time, these cancer cells begin to multiply and spread to the surrounding prostate tissue (the stroma) forming a tumor. Eventually, the tumor may grow large enough to invade nearby organs such as the seminal vesicles or the rectum, or the tumor cells may develop the ability to travel in the bloodstream and lymphatic system. Prostate cancer is considered a malignant tumor because it is a mass of cells that can invade other area of the body. This invasion of other organs is ...
Asthenozoospermia (or asthenospermia) is the medical term for reduced sperm motility. Complete asthenozoospermia, that is, 100 ... asthenozoospermia) than in men with oligozoospermia or teratozoospermia. Among men with asthenozoospermia, 31% were found to ... Causes of complete asthenozoospermia include metabolic deficiencies, ultrastructural abnormalities of the sperm flagellum (see ... Ortega, C.; Verheyen, G.; Raick, D.; Camus, M.; Devroey, P.; Tournaye, H. (2011). "Absolute asthenozoospermia and ICSI: What ...
... of DJ-1 Fails to Protect Mitochondrial Complex I Subunit NDUFS3 in the Testes and Contributes to the Asthenozoospermia. Yupeng ... of DJ-1 Fails to Protect Mitochondrial Complex I Subunit NDUFS3 in the Testes and Contributes to the Asthenozoospermia," ...
Asthenozoospermia (AS) is a common cause of human male infertility [1], characterized by reduced sperm motility (grade A + B ... S. M. Curi, J. I. Ariagno, P. H. Chenlo et al., "Asthenozoospermia: analysis of a large population," Archives of Andrology, vol ... A. J. Mundy, T. A. Ryder, and D. K. Edmonds, "Asthenozoospermia and the human sperm mid-piece," Human Reproduction, vol. 10, no ... Asthenozoospermia (AS), an important cause of male infertility, is characterized by reduced sperm motility. Among the ...
Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study. E. Salvolini, E. ... Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study (. ... and consequently an excess of tyrosine nitration are involved in the pathogenesis of idiopathic asthenozoospermia that causes ... in human spermatozoa isolated from normospermic fertile donors and infertile subjects affected by idiopathic asthenozoospermia ...
... ubiquinol in semen and is effective in improving sperm kinetic features in patients affected by idiopathic asthenozoospermia. ... Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial. ... article{Balercia2009CoenzymeQT, title={Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo- ...
Authors Antioxidant Therapy of Asthenozoospermia. Niloofar Agharezaee - Kambiz Gilany, - Mehrdad Hashemi, - Minoo Shahani - ... Asthenozoospermia is one of the most important causes of male infertility. Oxidative stress is one of the important mediators ... Agharezaee, Niloofar; Kambiz Gilany,; Mehrdad Hashemi, & Minoo Shahani, 2018, Antioxidant Therapy of Asthenozoospermia, Fourth ... Conclusion: The use of antioxidants is effective in treating asthenozoospermia disease, but different antioxidant supplements ...
What is asthenozoospermia or asthenospermia? How can it be detected? What is the most recommendable treatment option? Get ... Asthenozoospermia & infertility. Asthenozoospermia is a cause of male infertility. The ultimate goal of sperm cells is to ... FAQs from users: Can I conceive naturally with asthenozoospermia?, What are the symptoms of asthenozoospermia? and Are ... Diagnosing asthenozoospermia or any other sperm diagnosis with a single sperm analysis is a mistake, since it might be due to a ...
Asthenozoospermia is an infertility condition where a man produces sperm with reduced motility. Motility is a sperms... ... Asthenozoospermia Definition - What does Asthenozoospermia mean? Asthenozoospermia is an infertility condition where a man ... FertilitySmarts explains Asthenozoospermia. A sperm cell is composed of three parts, the head that holds the genetic material, ... Asthenozoospermia tends to occur in men with kidney disease, cystic fibrosis, and other genetic mutations. Although there is ...
Asthenozoospermia. Less than the normal number of moving sperm in the semen ...
Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia D Zuccarello 1 , A Ferlin, C ... Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia D Zuccarello et al. Hum Reprod. 2008 ... A DNAH17 missense variant causes flagella destabilization and asthenozoospermia. Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, ... Background: Asthenozoospermia (AZS) is a common cause of male infertility characterized by reduced forward motility (WHO grade ...
Association of GRP78 promoter polymorphisms and serum GRP78 level with risk of asthenozoospermia.. Qin H1,2, Wang R2,3, Pang X1 ... a Serum level of GRP78 in patients with asthenozoospermia and controls. b The serum GRP78 level of rs3216733 Gd/GG genotype and ... In addition, we performed association analysis between GRP78 promoter mutations and serum GRP78 level in asthenozoospermia. ... Association of GRP78 promoter polymorphisms and serum GRP78 level with risk of asthenozoospermia ...
Patients with asthenozoospermia (low progressive motility), teratozoopermia (abnormal morphology) and/or oligozoospermia (low ...
Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia. Posted by carlaasrm ... Category: Uncategorized · Tags: absolute asthenozoospermia, live birth, Retrograde ejaculation, sperm motility, theophylline ... Thirty-one-year-old nulliparous woman, and 39-year-old male with retrograde ejaculation and absolute asthenozoospermia. ... the use of ready-to-use theophylline is a feasible option in a case of retrograde ejaculation and absolute asthenozoospermia. ...
Coenzyme Q10 improves sperm kinetic features in patients with idiopathic asthenozoospermia.Jul 01, 2009. ...
The Outcome of Varicocelectomy on Sperm Parameters in Subfertile Men with Clinical Varicoceles Who Have Asthenozoospermia and ... The Outcome of Varicocelectomy on Sperm Parameters in Subfertile Men with Clinical Varicoceles Who Have Asthenozoospermia and ...
Asthenozoospermia. 5. 1. select. Asthma. 18. 6. select. Asthma: Bronchial. 6. 1. select. ...
Diseases : Asthenozoospermia. Pharmacological Actions : Spermatogenic. [+] Certain probiotics could potentially prevent ...
Asthenozoospermia. Fewer than 50% spermatozoa with forward progression(categories (a) and (b) or fewer than 25% spermatozoa ... Motility is assessed at the time of semen liquefaction and after 1 and 3 hours to detect asthenozoospermia. Manual counting ... The rare cases of monomorphic teratozoospermia as well as severe asthenozoospermia can be subjected to EM analysis to detect ...
Asthenozoospermia -- Low sperm motility.. Asymptomatic -- Having no symptoms.. Autoimmune -- An immune reaction against ones ...
A comprehensive gene mutation screen in men with asthenozoospermia.. Visser L, Westerveld GH, Xie F, van Daalen SK, van der ...
asthenozoospermia(MGI Ref ID J:5043). *coiled sperm flagellum*many sperm had coiled tails ...
Asthenozoospermia (human). Testicular cancer2 (human). Adjudin treatment (rat). Developmental stage-postnatal (mouse) ...
Among these infertile men, 18% specifically exhibit decreased motility of sperm (asthenozoospermia). Sperm motility is ...
L-carnitine in idiopathic asthenozoospermia: a multicenter study. Andrologia. 1994;26:155-159. ... or combined L-carnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia. Fertil Steril. 2005;84:662-671. ... or combined L-carnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia. Fertil Steril. 2005;84:662-671. ... double-blind randomized trial of the use of combined L-carnitine and L-acetyl-carnitine treatment in men with asthenozoospermia ...
Association of GRP78 promoter polymorphisms and serum GRP78 level with risk of asthenozoospermia. ...
  • According to embryologist Laura Mifsud , it is crucial to repeat the semen analysis before rendering a definitive diagnosis of asthenozoospermia to a patient. (invitra.com)
  • Combined pericoital intravaginal use of bee honey and royal jelly is a more effective, simpler, and less expensive therapy for infertility due to asthenozoospermia than h-IUI. (blogspot.com)
  • Can I conceive naturally with asthenozoospermia? (invitra.com)
  • Although there is not treatment for this condition, men with asthenozoospermia may still conceive children via an assisted reproductive technology (ART) such as In vitro fertilization (IVF). (fertilitysmarts.com)
  • Causes of complete asthenozoospermia include metabolic deficiencies, ultrastructural abnormalities of the sperm flagellum (see Primary ciliary dyskinesia) and necrozoospermia. (wikipedia.org)
  • Depending on the specific percent of immotile sperm that are present on the sample examined, we can distinguish several types of asthenozoospermia. (invitra.com)
  • Although there exists no specific value, we could determine that it is a severe case of asthenozoospermia if the percent of immotile sperm is close to 75-80% or even higher. (invitra.com)
  • Asthenozoospermia tends to occur in men with kidney disease, cystic fibrosis, and other genetic mutations. (fertilitysmarts.com)
  • A possible association of a human tektin-t gene mutation (A229V) with isolated non-syndromic asthenozoospermia: case report. (cdc.gov)
  • A comprehensive gene mutation screen in men with asthenozoospermia. (nih.gov)
  • Therefore, we used an antioxidant supplement for treating infertility for Iranian men.Material & Methods: We used antioxidant supplementation of Vitamin E, Folic acid and Selenium for 20 men with asthenozoospermia for a three months period. (civilica.com)
  • Conclusion: The use of antioxidants is effective in treating asthenozoospermia disease, but different antioxidant supplements should be evaluated with different doses to achieve the best results. (civilica.com)
  • In addition, we performed association analysis between GRP78 promoter mutations and serum GRP78 level in asthenozoospermia. (cdc.gov)
  • The aim of this study was undertaken to investigate the association of 78-kDa glucose-regulated protein (GRP78) gene promoter polymorphisms with risk of asthenozoospermia (AZS) men. (cdc.gov)
  • The study was carried out using 60 volunteers, 30 suffering from asthenozoospermia and 30 healthy controls. (separationsnow.com)
  • To analyze whether the use of ready-to-use theophylline is a feasible option in a case of retrograde ejaculation and absolute asthenozoospermia. (fertstertforum.com)
  • Among men with asthenozoospermia, 31% were found to have high levels of DNA fragmentation. (wikipedia.org)
  • Diagnosing asthenozoospermia or any other sperm diagnosis with a single sperm analysis is a mistake, since it might be due to a external or environmental factor, or a temporary circumstance of the patient. (invitra.com)
  • The rationale for this is as follows: if only a few are able to swim but they more progressively and forward, it can be qualified as mild asthenozoospermia. (invitra.com)