AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureHumanitiesInformation ScienceNamed GroupsHealth CarePublication CharacteristicsGeographicals
AstatineScandiumMetals, Alkaline EarthViral StructuresElementsLawrenciumRadiumFranciumMedicine in LiteratureLiterature, ModernScienceForeheadFamous PersonsDramaRNA HelicasesDictionaries, MedicalDictionaries as TopicDictionaries, ChemicalTerminology as TopicPhoneticsDictionaryDictionaries, PharmaceuticSiliconDiet FadsBooksKetogenic DietShoesBook SelectionCarisoprodolMeprobamateMuscle Relaxants, CentralBemegrideSomatosensory DisordersToe JointHistory, 15th CenturyFloridaComputer SecuritySingaporeWhiplash InjuriesBeta ParticlesPatents as TopicMetalsIsotopesIsotope LabelingCoronary RestenosisStentsChlorineChemical IndustryTransition TemperatureChlorine CompoundsHazardous SubstancesDisinfectantsChloramines
Astatine: Astatine. A radioactive halogen with the atomic symbol At, atomic number 85, and atomic weight 210. Its isotopes range in mass number from 200 to 219 and all have an extremely short half-life. Astatine may be of use in the treatment of hyperthyroidism.Scandium: Scandium. An element of the rare earth family of metals. It has the atomic symbol Sc, atomic number 21, and atomic weight 45.Metals, Alkaline Earth: Metals that constitute the group 2 (formerly group IIa) of the periodic table.Viral Structures: The structural parts of the VIRION.Elements: Substances that comprise all matter. Each element is made up of atoms that are identical in number of electrons and protons and in nuclear charge, but may differ in mass or number of neutrons.Lawrencium: Lawrencium. A radioactive actinide discovered in 1961. It has the atomic symbol Lr, atomic number 103, and atomic weight of 257. There are two isotopes with mass number 257 or 258, and mass number 256.Radium: Radium. A radioactive element of the alkaline earth series of metals. It has the atomic symbol Ra, atomic number 88, and atomic weight 226. Radium is the product of the disintegration of uranium and is present in pitchblende and all ores containing uranium. It is used clinically as a source of beta and gamma-rays in radiotherapy, particularly BRACHYTHERAPY.Francium: Francium. A radioactive alkali metal with the atomic symbol Fr, atomic number 87, and atomic weight 223. The mass numbers of other known isotopes are 204-213, 217-222, and 224. Its valence is +1.Medicine in Literature: Written or other literary works whose subject matter is medical or about the profession of medicine and related areas.Literature, ModernScience: The study of natural phenomena by observation, measurement, and experimentation.Forehead: The part of the face above the eyes.Famous PersonsDrama: A composition in prose or verse presenting in dialogue or pantomime a story involving various characters, usually intended to be acted on a stage and to be regarded as a form of entertainment. (From Random House Unabridged Dictionary, 2d ed)RNA Helicases: A family of proteins that promote unwinding of RNA during splicing and translation.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Dictionaries, ChemicalTerminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Phonetics: The science or study of speech sounds and their production, transmission, and reception, and their analysis, classification, and transcription. (Random House Unabridged Dictionary, 2d ed)DictionaryDictionaries, PharmaceuticSilicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].Diet Fads: Diets which become fashionable, but which are not necessarily nutritious.(Lehninger 1982, page 484)BooksKetogenic Diet: A course of food intake that is high in FATS and low in CARBOHYDRATES. This diet provides sufficient PROTEINS for growth but insufficient amount of carbohydrates for the energy needs of the body. A ketogenic diet generates 80-90% of caloric requirements from fats and the remainder from proteins.ShoesBook SelectionCarisoprodol: A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)Muscle Relaxants, Central: A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)Bemegride: A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.Somatosensory Disorders: Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation.Toe Joint: The articulation between the head of one phalanx and the base of the one distal to it, in each toe.History, 15th Century: Time period from 1401 through 1500 of the common era.FloridaComputer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.SingaporeWhiplash Injuries: Hyperextension injury to the neck, often the result of being struck from behind by a fast-moving vehicle, in an automobile accident. (From Segen, The Dictionary of Modern Medicine, 1992)Beta Particles: High energy POSITRONS or ELECTRONS ejected from a disintegrating atomic nucleus.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Metals: Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)Isotopes: Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)Isotope Labeling: Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms.Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Chlorine: A greenish-yellow, diatomic gas that is a member of the halogen family of elements. It has the atomic symbol Cl, atomic number 17, and atomic weight 70.906. It is a powerful irritant that can cause fatal pulmonary edema. Chlorine is used in manufacturing, as a reagent in synthetic chemistry, for water purification, and in the production of chlorinated lime, which is used in fabric bleaching.Chemical Industry: The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed)Transition Temperature: The temperature at which a substance changes from one state or conformation of matter to another.Chlorine Compounds: Inorganic compounds that contain chlorine as an integral part of the molecule.Hazardous Substances: Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.Disinfectants: Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)Chloramines

211At- and 131I-labeled bisphosphonates with high in vivo stability and bone accumulation. (1/53)

Bisphosphonates were synthesized for use as carriers for astatine and iodine radioisotopes to target bone neoplasms. METHODS: Radiohalogenated activated esters were coupled to the amino group in the side chain of the bisphosphonate. The bisphosphonate 3-amino-1-hydroxypropylidene bisphosphonate was combined with four different acylation agents: N-succinimidyl 3-[211At]astatobenzoate, N-succinimidyl 3-[131I]iodobenzoate, N-succinimidyl-5-[211At]astato-3-pyridinecarboxylate and N-succinimidyl-5-[131I]iodo-5-pyridinecarboxylate. The products, 3-[131I]iodobenzamide-N-3-hydroxypropylidene-3,3-bisphosphonate (IBPB), 3-[211At]astato-benzamide-N-3-hydroxypropylidene-3,3-bisphosphonat e (ABPB), 5-[131I]iodopyridine-3-amide-N-3-hydroxypropylidene-3,3-bisphospho nate (IPPB) and 5-[211At]astatopyridine-3-amide-N-3-hydroxypropylidene-3,3-bisphos phonate (APPB), were injected intravenously into Balb/c mice. MIRD and Monte Carlo methods were used on the basis of cumulated activity calculated from biodistribution data to estimate dose to organs and bone segments. RESULTS: All 131I- and 211At-labeled analogs were strongly incorporated into osseous tissue and retained there at stable levels, while a rapid clearance from blood was observed. The bone uptake was found to be similar for 211At- and 131I-labeled bisphosphonate when compared in paired label experiments. Bone uptake and bone-to-tissue ratios were better for IBPB compared with IPPB, and ABPB compared with APPB. All four compounds appeared to be highly resistant to in vivo dehalogenation as indicated by low uptake of 131I/211At in the thyroid gland and stomach. According to dosimetric estimates, the bone surface-to-bone marrow ratio was three times higher with 211At than with 131I. CONCLUSION: Both the beta-particle- and alpha-particle-emitting compounds showed high in vivo stability and excellent affinity for osseous tissue. Further preclinical evaluation is therefore warranted.  (+info)

Demonstration of highly specific toxicity of the alpha-emitting radioimmunoconjugate(211)At-rituximab against non-Hodgkin's lymphoma cells. (2/53)

The ability of an alpha-emitter conjugated to a chimaeric anti-CD20 monoclonal antibody to kill selectively human B-lymphoma cells in vitro is reported. Two B-lymphoma cell lines RAEL and K422, and normal haematopoietic progenitor cells from human bone marrow aspirates were incubated with(211)At-rituximab (Rituxan(R) or MabTheratrade mark) and plated in clonogenic assays for survival analyses. Following 1 h incubation with(211)At-rituximab, in concentrations which gave an initial activity of 50 kBq ml(-1), a high tumour cell to normal bone marrow cell toxicity ratio was obtained; 4.1 to 1.0 log cell kill. Biodistribution studies of(211)At-rituximab in Balb/c mice showed similar stability as that of the iodinated analogue. The data indicate that testing of(211)At-rituximab in human patients is warranted.  (+info)

High-level production of alpha-particle-emitting (211)At and preparation of (211)At-labeled antibodies for clinical use. (3/53)

In vitro and in vivo studies in human glioma models suggest that the antitenascin monoclonal antibody 81C6 labeled with the 7.2-h-half-life alpha-particle emitter (211)At might be a valuable endoradiotherapeutic agent for the treatment of brain tumors. The purpose of this study was to develop methods for the production of high levels of (211)At and the radiosynthesis of clinically useful amounts of (211)At-labeled human/mouse chimeric 81C6 antibody. METHODS: (211)At was produced through the (209)Bi(alpha, 2n)(211)At reaction using an internal target system and purified by a dry distillation process. Antibody labeling was accomplished by first synthesizing N-succinimidyl 3-[(211)At]astatobenzoate from the corresponding tri-n-butyl tin precursor and reacting it with the antibody in pH 8.5 borate buffer. Quality control procedures consisted of methanol precipitation, size-exclusion high-performance liquid chromatography (HPLC), and pyrogen and sterility assays, as well as determination of the immunoreactive fraction by a rapid procedure using a recombinant tenascin fragment coupled to magnetic beads. RESULTS: A total of 16 antibody labeling runs were performed. Using beam currents of 50-60 microA alpha-particles and irradiation times of 1.5-4.5 h, the mean (211)At production yield was 27.75 +/- 2.59 MBq/microA.h, and the maximum level of (211)At produced was 6.59 GBq after a 4-h irradiation at 55 microA. The decay-corrected distillation yield was 67% +/- 16%. The yield for the coupling of the (211)At-labeled active ester to the antibody was 76% +/- 8%. The fraction of (211)At activity that eluted with a retention time corresponding to intact IgG on HPLC was 96.0% +/- 2.5%. All preparations had a pyrogen level of <0.125 EU/mL and were determined to be sterile. The mean immunoreactive fraction for these 16 preparations was 83.3% +/- 5.3%. Radiolysis did not interfere with labeling chemistry or the quality of the labeled antibody product. CONCLUSION: These results show that it is feasible to produce clinically relevant activities of (211)At-labeled antibodies and have permitted the initiation of a phase I trial of (211)At-labeled chimeric 81C6 administered directly into the tumor resection cavities of brain tumor patients.  (+info)

Comparative cellular catabolism and retention of astatine-, bismuth-, and lead-radiolabeled internalizing monoclonal antibody. (4/53)

Monoclonal antibodies (mAbs) labeled with alpha-emitting radionuclides such as (211)At, (212)Bi, (213)Bi, and (212)Pb (which decays by beta-emission to its alpha-emitting daughter, (212)Bi) are being evaluated for their potential applications for cancer therapy. The fate of these radionuclides after cells are targeted with mAbs is important in terms of dosimetry and tumor detection. METHODS: In this study, we attached various radionuclides that result in alpha-emissions to T101, a rapidly internalizing anti-CD5 mAb. We then evaluated the catabolism and cellular retention and compared them with those of (125)I- and (111)In-labeled T101. T101 was labeled with (211)At, (125)I, (205,6)Bi, (111)In, and (203)Pb. CD5 antigen-positive cells, peripheral blood mononuclear cells (PBMNC), and MOLT-4 leukemia cells were used. The labeled T101 was incubated with the cells for 1 h at 4 degrees C for surface labeling. Unbound activity was removed and 1 mL medium added. The cells were then incubated at 37 degrees C for 0, 1, 2, 4, 8, and 24 h. The activity on the cell surface that internalized and the activity on the cell surface remaining in the supernatant were determined. The protein in the supernatant was further precipitated by methanol for determining protein-bound and non-protein-bound radioactivity. Sites of internal cellular localization of radioactivity were determined by Percoll gradient centrifugation. RESULTS: All radiolabeled antibodies bound to the cells were internalized rapidly. After internalization, (205,6)Bi, (203)Pb, and (111)In radiolabels were retained in the cell, with little decrease of cell-associated radioactivity. However, (211)At and (125)I were released from cells rapidly ((211)At < (125)I) and most of the radioactivity in the supernatant was in a non-protein-bound form. Intracellular distribution of radioactivity revealed a transit of the radiolabel from the cell surface to the lysosome. The catabolism patterns of MOLT-4 cells and PBMNC were similar. CONCLUSION: (211)At catabolism and release from cells were somewhat similar to that of (125)I, whereas (205,6)Bi and (203)Pb showed prolonged cell retention similar to that of (111)In. These catabolism differences may be important in the selection of alpha-radionuclides for radioimmunotherapy.  (+info)

Microdosimetric analysis of alpha-particle-emitting targeted radiotherapeutics using histological images. (5/53)

The purpose of this study was to evaluate the therapeutic efficacy and limitations of alpha-particle-emitting radiolabeled compounds by means of 2-dimensional histological images and distribution of activity on a microscopic level. METHODS: A microdosimetric approach based on histological images is used to analyze the therapeutic effectiveness of alpha-particle-emitting (211)At and (213)Bi conjugated to 201B monoclonal antibody (mAb), which is reactive with murine lung blood vessels for the treatment of EMT-6 lung tumor colonies in nude mice. Autoradiography images were used to define the tissue morphology and activity distribution within lung tissues. Two animal groups were studied: Group A consisted of animals bearing small tumors (<130 micro m) and group B consisted of larger tumors (<600 micro m). Probability density functions (pdf) described the variability in average absorbed dose and survival probability among normal and tumor target cells and, in turn, were used to assess the survival fraction of tumor and normal tissue. RESULTS: The average absorbed dose to tumor cells per unit cumulated activity concentration for animals in group A was 1.10 x 10(-3) and 1.37 x 10(-3) Gy g MBq(-1) s(-1) for (211)At and (213)Bi, respectively, and for animals in group B was 3.8 x 10(-4) and 5.6 x 10(-4) Gy g MBq(-1) s(-1) for (211)At and (213)Bi, respectively. The fraction of tumor cells that received a zero absorbed dose for animals in group A was 0.04% for (213)Bi and 0.2% for (211)At and for animals in group B was 25% for (213)Bi and 31% for (211)At. Both (213)Bi- and (211)At-labeled 201B mAb were effective therapies for animals with small tumors, where predicted therapeutic effectiveness was consistent with experimental findings; however, they were ineffective for animals with larger tumors. CONCLUSION: Microdosimetric methods based on knowledge of tissue morphology and activity distribution on a small-scale level can be a useful tool for evaluating a priori the therapeutic efficacy and limitations of targeted alpha-particle endoradiotherapeutic strategies.  (+info)

(211)At-labeled and biotinylated effector molecules for pretargeted radioimmunotherapy using poly-L- and poly-D-Lysine as multicarriers. (6/53)

Poly-L- and poly-D-lysine were evaluated as carriers of astatine and biotin for prospective use as effector molecules in pretargeted radioimmunotherapy of micrometastases. The precursor polylysine was derivatized in a three-step, single-pot procedure, including biotinylation with biotin amidocaproic N-hydroxysuccinimide, astatination via the intermediate reagent N-succinimidyl 3-(trimethylstannyl)benzoate, and, finally, charge modification using succinic anhydride. The chemistry was shown to be very facile, with a biotinylation efficiency of 75 +/- 5%, and overall radiochemical yields in the range of 50-70%. After charge modification, no amines could be detected in the final product. The biotin function was unaffected by the chemistry and the radiation, as confirmed by almost complete binding of the effector molecule to avidin beads using a convenient filter tube assay. The effector molecules were evaluated in tumor-free female nude mice with regard to whole-body retention and tissue distribution after i.p. administration. The distribution of the L-isomer effector molecule showed rapid whole-body clearance with low uptake in all tissues, whereas the D-isoform showed whole-body clearance related to uptake in the kidneys. Both D-isomer and L-isomer showed faster blood clearance and generally lower tissue uptakes than labeled antibodies. The normal tissue distribution after the peritoneal administration implies that pretargeting using L-structure polylysine as the effector molecule may give a higher therapeutic index than that achieved in conventional radioimmunotherapy.  (+info)

Astatine-211-labeled antibodies for treatment of disseminated ovarian cancer: an overview of results in an ovarian tumor model. (7/53)

PURPOSE: The aim of the study was to establish and refine a preclinical model to alpha-immunoradiotherapy of ovarian cancer. EXPERIMENTAL DESIGN: At-211 was produced by cyclotron irradiation of a bismuth-209 target and isolated using a novel dry distillation procedure. Monoclonal antibodies were radiohalogenated with the intermediate reagent N-succinimidyl 3-(trimethylstannyl)benzoate and characterized in terms of radiochemical yield and in vitro binding properties. In vitro OVCAR-3 cells were irradiated using an external Cobalt-60 beam, as reference, or At-211-albumin and labeled antibody. Growth assays were used to establish cell survival. A Monte Carlo program was developed to simulate the energy imparted and the track length distribution. Nude mice were used for studies of WBC depression, with various activities of Tc-99m antibodies, as reference, and At-211 antibodies. In efficacy studies, OVCAR-3 cells were inoculated i.p., and animals were treated 2 weeks later. The animals were either dissected 6 weeks later or followed-up for long-term survival. RESULTS: A rapid distillation procedure, as well as a rapid and high-yield, single-pot labeling procedure, was achieved. From growth inhibition data, the relative biological effectiveness of the alpha-emission for OVCAR-3 cells was estimated to be approximately 5, which is in the same range as found in vivo for hematological toxicity. At-211 MOv18 was found to effectively inhibit the development of tumors and ascites, also resulting in long-term survival without significant toxic effect. CONCLUSIONS: Use of the short-range, high-linear energy transfer alpha-emitter At-211 conjugated to a surface epitope-recognizing monoclonal antibody appears to be highly efficient without significant toxicity in a mouse peritoneal tumor model, urging a Phase I clinical trial.  (+info)

In vitro cytotoxicity of (211)at-astatide and (131)I-iodide to glioma tumor cells expressing the sodium/iodide symporter. (8/53)

The sodium/iodide symporter (NIS) has been identified as an attractive target for cancer therapy. The efficacy of (131)I-iodide for NIS-expressing tumor therapy may be limited by a combination of poor cellular retention and unfavorable physical characteristics (long physical half-life and low linear-energy-transfer [LET] radiative emissions). On the other hand, (211)At-astatide is also transported by NIS and offers several therapeutic advantages over (131)I-iodide due to its physical characteristics (short half-life, high LET alpha-particle emissions). The objective of this study was to directly compare the radiotoxicity of both radionuclides using a NIS-transfected cultured cell model. METHODS: Cytotoxicity was determined by colony-forming assays. Also, a first-order pharmacokinetic model was used to simulate the closed compartmental system between the medium and cells. Experimental data were then fitted to this model and used to estimate the transfer coefficients between medium and cells, k(m)(c), and between cells and medium, k(c)(m). Using the pharmacokinetic model, the cumulated activity concentrations in the medium and cells were calculated. Monte Carlo transport methods were then used to assess absorbed doses from (131)I and (211)At. RESULTS: (211)At-Astatide was significantly more cytotoxic than (131)I-iodide in this closed compartmental system. For (211)At-astatide, absorbed doses per unit administered activity were 54- to 65-fold higher than for (131)I-iodide. Both NIS-expressing and control cells showed increased sensitivity to (211)At over (131)I, with significantly lower D(0) (absorbed dose required to reduce the survival fraction to e(-1)) and SF(2) (2-Gy survival fraction) values, highlighting the higher intrinsic cytotoxicity of alpha-particles. However, NIS-independent (nonspecific) binding of (211)At-astatide was higher than that of (131)I-iodide, therefore, yielding a lower absorbed dose ratio between NIS-transfected and -nontransfected cells. CONCLUSION: Treatment of NIS-expressing cells with (211)At-astatide resulted in higher absorbed doses and increased cytotoxicity per unit administered activity than that observed with (131)I-iodide. These results suggest that (211)At-astatide may be a promising treatment strategy for the therapy of NIS-expressing tumors.  (+info)

Periodic Table of Elements: Astatine - At (EnvironmentalChemistry.com)  Periodic Table of Elements: Astatine - At (EnvironmentalChemistry.com)
Comprehensive information for the element Astatine - At is provided by this page including scores of properties, element names in many languages, most known nuclides and technical terms are linked to their definitions.
https://environmentalchemistry.com/yogi/periodic/At.html
BIOETYMOLOGY : ORIGIN IN BIOMEDICAL TERMS: astatine (At)  BIOETYMOLOGY : ORIGIN IN BIOMEDICAL TERMS: astatine (At)
For many years scientists had noticed that in Mendeleev published periodic table was a space underneath iodine known theoretically as eka-iodine but no one could identified in nature this element. In 1940, finally, the element was detected and produced by Americans physicts D.R Corson(1914-2012), K R Mackenzie (1912-2002), E Segre (1905-1989) in California by bombarding bismuth-209 with alpha particles in a cyclotron ...
http://bioetymology.blogspot.com/2012/08/astatine-at.html
BIS(TRIMETHYLSTANNYL)ACETYLENE 2117-50-2 Chemical Safety Info Safety Info  BIS(TRIMETHYLSTANNYL)ACETYLENE 2117-50-2 Chemical Safety Info Safety Info
BIS(TRIMETHYLSTANNYL)ACETYLENE 2117-50-2 safety info, BIS(TRIMETHYLSTANNYL)ACETYLENE chemical safety search, Chemical BIS(TRIMETHYLSTANNYL)ACETYLENE safety technical specifications ect.
http://www.molbase.com/en/safetyinfo_2117-50-2-moldata-46437.html
Patent US5720935 - Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from ... - Google Patents  Patent US5720935 - Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from ... - Google Patents
A method of making a radiolabeled pyrimidine nucleoside or nucleotide is described. In the method, a stannylated pyrimidine nucleoside or nucleotide is contacted in an aqueous solution with a radioactive iodide, bromide, chlorine or astatine ion in the presence of an acidic hydrogen peroxide oxidizing solution comprising at least a 3:1 ratio of 30% hydrogen peroxide to 1N acid (v/v), whereby a water soluble pyrimidine nucleoside or nucleotide labeled with radioactive iodine, bromine, chlorine or astatine is formed. Kits suitable for practicing the method are also disclosed.
http://www.google.com/patents/US5720935
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Most recent papers with the keyword Antibody purification | Read by QxMD  Most recent papers with the keyword Antibody purification | Read by QxMD
In this report we describe the development of an alternative approach to arylstannane chemistry for radiolabeling antibodies with radioiodine or astatine based on aryliodonium salts precursors. Bifunctional aryliodonium salts were designed and tested for the synthesis of (125)I and (211)At labeled prosthetic groups for bioconjugation. The nature of the electron rich aryl group was varied and its impact on the regioselectivity of radiohalogenation was evaluated. Unexpectedly, whereas the 2-thienyl group provided the best regioselectivity towards the radioiodination of the aryl moiety of interest (98:2), it was less selective for astatination (87:13); the anisyl group providing the best regioselectivity of astatination (94:6 ...
https://www.readbyqxmd.com/keyword/45211
High School Chemistry/Families on the Periodic Table - Wikibooks, open books for an open world  High School Chemistry/Families on the Periodic Table - Wikibooks, open books for an open world
Elements Ending with s2p5 = Halogens The halogens are an interesting group. Halogens are members of Group 7A, which is also referred to as 17. It is the only group in the Periodic Table that contains all of the states of matter at room temperature. Fluorine, F2, is a gas, as is chlorine, Cl2. Bromine, Br2, is a liquid and iodine, I2, and astatine, At2, are both solids. What else is neat about Group 7A is that it houses four (4) of the seven (7) diatomic compounds. Remember the diatomics are H2, N2, O2, F2, Cl2, Br2, and I2. Notice that the latter four are Group 17 elements. The word halogen comes from the Greek meaning salt forming. French chemists discovered that the majority of halogen ions will form salts when combined with metals. We all know some of these already: LiF, NaCl, KBr, and NaI. Taking a look at Group 7A in the figure, we can find the same pattern of similar electron configurations as found with group 1A, 2A, and 8A. It is the 17th group in the Periodic Table and it contains only ...
https://en.wikibooks.org/wiki/High_School_Chemistry/Families_on_the_Periodic_Table
LifeGuard™ LSZH Cables | Houston Wire & Cable Co.  LifeGuard™ LSZH Cables | Houston Wire & Cable Co.
Halogens are a group of highly reactive elements including fluorine, chlorine, bromine, iodine and astatine. When products containing halogens are burned, they produce very dangerous gasses. Public awareness of these dangers began after several tragic fires claimed the lives of victims who inhaled deadly halogenated fumes.. Several fires, including those at the Beverley Hills Supper Club, Londons Kings Cross Underground Station and Germanys Düsseldorf Airport, have lead to important changes that significantly limit where cables containing halogens may be used. Many organizations, local authorities and governments have undertaken broad initiatives to eliminate the production of halogenated material. In Asia, the United Kingdom and many European communities, the use of wire and cable containing halogens is highly regulated, and in some areas completely prohibited.. ...
https://www.houwire.com/lifeguard-cables/
Science Makes Sense,Week21 : The Halogens, refrigerants, toothpaste and disinfectants. | Chobhis Blog  Science Makes Sense,Week21 : The Halogens, refrigerants, toothpaste and disinfectants. | Chobhi's Blog
What does an older refrigerator, bleach,toothpaste and pesticides have in common? All contain one or more halogens, the Group VII elements of the Periodic Table: fluorine, chlorine, bromine or iodine. (Astatine is radioactive and does not behave like the other halogens.) Today we shall study these very reactive elements, sitting so close to the most…
https://chobhi.org/2016/01/18/science-makes-senseweek21-the-halogens-refrigerants-toothpaste-and-disinfectants/
Science - NWChem  Science - NWChem
Sergentu D-C, D Teze, A Sabatié-Gogova, C Alliot, N Guo, F Bassal, I Da Silva, D Deniaud, R Maurice, J Champion, N Galland, and G Montavon. 2016. "Advances on the Determination of the Astatine Pourbaix Diagram: Predomination of AtO(OH)2− over At− in Basic Conditions." Chemistry - A European Journal 22:2964-2971 ...
http://www.nwchem-sw.org/index.php?title=Science&oldid=8045
Model Railway Layouts O Gauge PDF Layout Plans o n ho Scale g z s Gauge | trainlayouts  Model Railway Layouts O Gauge PDF Layout Plans o n ho Scale g z s Gauge | trainlayouts
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Woodworking Apprenticeship wood projects boxes diy ideasplandlbuild  Woodworking Apprenticeship wood projects boxes diy ideasplandlbuild
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2013-05-18 Sat  2013-05-18 Sat
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Targeting EGFR and HER2 with 211At-labeled molecules : unexpected and expected dose-effect relations in cultured tumor cells  Targeting EGFR and HER2 with 211At-labeled molecules : unexpected and expected dose-effect relations in cultured tumor cells
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Oncology, Radiology and Clinical Immunology, Biomedical Radiation Sciences.ORCID iD: 0000-0001-6120-2683 ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:217056
Integrin Targeted Delivery of Radiotherapeutics  Integrin Targeted Delivery of Radiotherapeutics
1. Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer. 2003;3:401-10 2. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000;407:249 3. Sharma RA, Harris AL, Dalgleish AG, Steward WP, OByrne KJ. Angiogenesis as a biomarker and target in cancer chemoprevention. Lancet Oncol. 2001;2:726-32 4. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995;1:27-31 5. Cai W, Niu G, Chen X. Imaging of integrins as biomarkers for tumor angiogenesis. Curr Pharm Des. 2008;14:2943-73 6. Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell. 2002;110:673-87 7. Cai W, Wu Y, Chen K, Cao Q, Tice DA, Chen X. In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin αvβ3. Cancer Res. 2006;66:9673-81 8. Cooper CR, Chay CH, Pienta KJ. The role of αvβ3 in prostate cancer progression. Neoplasia. 2002;4:191-4 9. Hood JD, Cheresh DA. Role of integrins in cell ...
https://www.thno.org/v01p0201.htm
Anes Osmić: Čija je vagina? | Tacno.net  Anes Osmić: Čija je vagina? | Tacno.net
U muškocentričnom, mizoginom društvu još uvijek me iz takta umije izbaciti više šovinistička nego jezička konstrukcija „davanje vagine
https://zenesainterneta.wordpress.com/2014/09/17/anes-osmic-cija-je-vagina-tacno-net/
Jagen in der schweiz buch - Super Manuals Storage  Jagen in der schweiz buch - Super Manuals Storage
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http://gmmusic.tk/2017/06/15/jagen-in-der-schweiz-buch_gk/
Science Matters Bulletin Board Sign by Lani Browne | TpT  Science Matters Bulletin Board Sign by Lani Browne | TpT
Just print, cut, and arrange this bulletin board sign that spells out "Science Matters" in letters in the style of the Periodic Table! Each box is 5 in. x 5 in. and once arranged as shown, it creates a 30 in. x 10 in. sign. Comes with 10 squares to be arranged to read ScIENCe MAtTeRS: Seven squares depict real period table boxes and are black with white writing: - Scandium (Sc) - Iodine (I) - Nitrogen (N) - Cerium (Ce) - Astatine (At) - Tellurium (Te) - Sulfur (S)
https://www.teacherspayteachers.com/Product/Science-Matters-Bulletin-Board-Sign-2778253
5:19 am  5:19 am
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Woodworking Plans And Projects woodworking plans outdoor table diy ideas  Woodworking Plans And Projects woodworking plans outdoor table diy ideas
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http://mrfreeplans.de.vu/2014/03/19/woodworking-plans-and-projects-randkey-diy-ideas/
Alfa Aesar™ N-Boc-L-phenylalanine N-succinimidyl ester, 98% 250mg Alfa Aesar™ N-Boc-L-phenylalanine N-succinimidyl ester, 98%  Alfa Aesar™ N-Boc-L-phenylalanine N-succinimidyl ester, 98% 250mg Alfa Aesar™ N-Boc-L-phenylalanine N-succinimidyl ester, 98%
Alfa Aesar™ N-Boc-L-phenylalanine N-succinimidyl ester, 98% 250mg Alfa Aesar™ N-Boc-L-phenylalanine N-succinimidyl ester, 98% Amino Acids
https://www.fishersci.co.uk/shop/products/n-boc-l-phenylalanine-n-succinimidyl-ester-98-2/15477316
Anesthesia (ANES) | Stanford University  Anesthesia (ANES) | Stanford University
ANES 203. Evaluating New Health Care Ventures: An Everyone Included¿ Approach. 1-2 Unit.. With ever-growing innovation in healthcare, how do investors evaluate and fund new ventures in one of the most diverse, operationally complex and regulated industries? Health care investment is unique in its dynamic evolution across decades of scientific, business and regulatory development. How might patients, providers, technologists, and investors¿which we define as our Stanford Medicine X Everyone Included¿ team model ¿help identify the best opportunities for the health care investor? This course focuses on how health care investors think and make strategic decisions, incorporating both changing financial metrics and qualitative investment theses. This colloquium will feature guest speakers including senior investment professionals, visionary business leaders and passionate new voices such as patient experts that have traditionally been absent from investment decisions. Students enrolling for 2 ...
http://exploredegrees.stanford.edu/coursedescriptions/anes/
Rounding in the Intensive Care Unit - Crashing Patient  Rounding in the Intensive Care Unit - Crashing Patient
From the call room, 6th straight overnight, so forgive the grammar, typo, conceptual errors of an exhausted brain. One fellow to another, this attempt at an answer from the perspective of seeing some light near the end of 2 ccm fellowships after 10 years of EM attending practice, first was anes, then internal med.. So, 2 pieces of advice, one from the best EM doc, if not the best doc, period, I know, Rick Bruno. The other from my former fellowship director Jean Charchaflieh, ie from the anes ccm program, but much built in from other wise folks.. From Rick Bruno when I asked him as a new 4th year EM res, how to run a complicated trauma or medical or peds resus,"Rick, whats in your brain as background noise," he said: "what am I missing, what am I missing, what am I missing?".. From Jean Charchaflieh, my anes-ccm fellowship director: "Seth this world is too complex, and youre not Spiro (a pulm-ccm mentor from that first fellowship), so no ER attending or 30-year unit veteran one sentence ...
https://crashingpatient.com/intensive-care/icu-rounds.htm/
Short Range Alpha-Particles from Fluorine Bombarded with Protons - CaltechAUTHORS  Short Range Alpha-Particles from Fluorine Bombarded with Protons - CaltechAUTHORS
The ranges of the alpha-particles proceeding from the 334-, 867-, 927-, 1220-, and 1363-kev resonances in the bombardment of fluorine with protons were measured. The Qs of those particles obtained at 334, 867, 927, and 1363 kev were found to be identical, and have the value 1.81 ± 0.04 Mev. The Q of the low energy alpha-particles obtained at the 1220-kev resonance was found to be 1.93±0.07 Mev. The two values thus yield an energy separation of 0.12±0.08 Mev for the two corresponding states of O16. In addition it was shown that at least one of the two resonances which are in the neighborhood of 900 kev must yield short range alpha-particles whose angular distribution is not spherically symmetric. ...
https://authors.library.caltech.edu/2372/
Protons from the alpha-particle bombardment of 31P  Protons from the alpha-particle bombardment of 31P
Resonances in the yield of ground-state protons from alpha-particle bombardment of 31P were investigated in the energy range Eα = 1.7 − 3.3 MeV. Fourteen resonances were observed, none of which was known before. Resonance energies and strengths are presented. Angular distribution measurements lead to unique values of the resonance ... read more spin in all cases but one. The exception is the strong resonance at Eα = 3.302 MeV, which shows a deviation from forward-backward symmetry in the angular distribution, to be explained by assuming interference with some unknown broad resonance(s) with opposite parity, probably at higher energy. show less ...
https://dspace.library.uu.nl/handle/1874/17656
Repair Standard Error Bars Interpretation Tutorial  Repair Standard Error Bars Interpretation Tutorial
Fidler, J. v t e Retrieved from "https://en.wikipedia.org/w/index.php?title=Error_bar&oldid=746427703" Categories: Statistical charts and diagramsStatistics stubsHidden categories: All stub articles Navigation menu Personal tools Not logged inTalkContributionsCreate accountLog in Namespaces Article Talk Variants Views Read Confidence Interval Error Bars Now click on the Custom button as the method for entering the Error amount. 95 Confidence Interval Error Bars Combining that relation with rule 6 for SE bars gives the rules for 95% CIs, which are illustrated in Fig. 6. http://www.ehow.com/how_2049858_make-tinfoil-hat.html #14 mweed August 5, 2008 The tradition to use SEM in psychology is unfortunate because you cant just look at the graph and determine significance, but you do get some weblink Both cases are in molecular biology, unsurprisingly. #9 Michael Anes August 1, 2008 Frederick, You state "Personally I think standard error is a bad choice because its only well defined for We could ...
http://kldns.net/error-bars/standard-error-bars-interpretation.html
Postime nga Virgjil Muci  Postime nga Virgjil Muci
Në një nga numrat e prillit, e përjavshmja në zë The New Yorkerbotonte një shkrim të George Parkerit rreth censurës e autocensurës, si një prej rreziqeve të mëdha, ndër të tjera, që i kanosen sot lirisë së shprehjes e të.... Lexo artikullin ...
https://al.ejo-online.eu/author/virgjil-muci
Official ESCRS | European Society of Cataract & Refractive Surgeons  Official ESCRS | European Society of Cataract & Refractive Surgeons
On 20 consecutive eyes with cataract before the stage of capsulorrhexsis a specially designed silicone ring (Verus Capsulorhexis Device, Mile High Ophthalmics) was implanted in the anterior chamber. Along its inner edge serving as a guide a continuous round capsulorrhexis was performed ...
http://www.escrs.org/Copenhagen2016/programme/posters-details.asp?id=25503
College of DuPage Course Catalog - Anesthesia Technology (ANES)  College of DuPage Course Catalog - Anesthesia Technology (ANES)
Students continue to learn the theory and concepts of the surgical environment as it relates to anesthesia. Topics of discussion will include basic case set-up utilizing anesthesia supplies and equipment. Lastly, there will be an in-depth exploration of the function and handling of anesthesia equipment, supplies for various surgical procedures including general cases, regional anesthesia, and procedural sedation. Prerequisite: Anesthesia Technology 1501 with a grade of C or better, or equivalent.Admission to the program and consent of instructor is required. (9 lecture hours, 4 lab hours) ...
https://www.cod.edu/catalog/current/courses/anesthesia_technology/index.aspx
April current affairs 2015  April current affairs 2015
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2n2222a 331 datasheet  2n2222a 331 datasheet
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dali te nesto muci  dali te nesto muci
Mrzis skolu…? Oni ne! . Mrzis kada te tjeraju da jedes...? Oni mrze glad! . Zivimo na dijeti..? Mnogi umiru od gladi! . Mislis da roditelji previse brinu o tebi..? Oni nemaju roditelje!!! . Dosadjuju nam uobicajene igre...? Kod njih nema izbora! . Zelis Adidas a kupe ti Nike...? Oni imaju samo ovu marku!!! . Mrzis kad te posalju na spavanje...? Neki se ljudi najradije ne bi probudili... . I ako te jos nesto NO TE QUEJES! muci.... . Pogledaj oko sebe i budi zahvalan za sve sto ti se pruza . Mi smo sretni, i imamo vise nego sto nam treba za lijep i ispunjen zivot. Daj da pokusamo da ne podrzavamo ovaj cudan put nemoralne potrosnje, koju nam nudi ovo "moderno i napredno" drustvo, koje precesto zaboravlja i ignorira dvije trecine covjecanstva. . Ako ovu prezentaciju ne posaljes dalje, naravno da se nece desiti nista lose. Svejedno, nemoj je zadrzati za sebe. Enviemos Posalji je barem jednoj osobi. Nece biti uzalud. . Manje se zalimo, a dajmo vise. ...
https://www.scribd.com/doc/22892923/dali-te-nesto-muci
Kuci muci online dating | Porno photo  Kuci muci online dating | Porno photo
Complete kuci muci online dating pron videos - A free online dating & social networking site specifically for classical music lovers . Browse the Classical Music Groups to find other classical musical afficianados.
http://giftcardbalance.info/teacher/kuci-muci-online-dating.php
EVZ: Muci si suruburi | Zvoner.ro  EVZ: Muci si suruburi | Zvoner.ro
Propun traducatorilor de stiri de la Evenimentul Zilei sa foloseasca si celelalte expresii care se preteaza la traducerea cuvantului "nuts":. - Borcan plin de testicole si suruburi. - Borcan plin de nebuni si suruburi. - Borcan plin de prostii si suruburi.. - Borcan plin cu o chinta regala si suruburi.. E greu sa lucrezi in presa…. (Poza este pentru referinta, probabil ca vor repara monumentala gafa de traducere…). ...
http://www.zvoner.ro/evz-muci-si-suruburi/
The Daily WTF: Curious Perversions in Information Technology  The Daily WTF: Curious Perversions in Information Technology
And hydrogen and oxygen and nitrogen and rhenium, And nickel, neodymium, neptunium, germanium, And iron, americium, ruthenium, uranium, Europium, zirconium, lutetium, vanadium, And lanthanum and osmium and astatine and radium, And gold and protactinium and indium and gallium, ,gasp, And iodine and thorium and thulium and thallium.. Theres yttrium, ytterbium, actinium, rubidium, And boron, gadolinium, niobium, iridium, And strontium and silicon and silver and samarium, And bismuth, bromine, lithium, beryllium, and barium.. Theres holmium and helium and hafnium and erbium, And phosphorus and francium and fluorine and terbium, And manganese and mercury, molybdenum, magnesium, Dysprosium and scandium and cerium and cesium. And lead, praseodymium, and platinum, plutonium, Palladium, promethium, potassium, polonium, And tantalum, technetium, titanium, tellurium, ,gasp, And cadmium and calcium and chromium and curium.. Theres sulfur, californium, and fermium, berkelium, And also mendelevium, ...
https://thedailywtf.com/articles/comments/Ternary-Over-a-New-Leaf
Patent US4761335 - Alpha-particle protection of semiconductor devices - Google Patents  Patent US4761335 - Alpha-particle protection of semiconductor devices - Google Patents
The present invention is a tape product suitable for use in the protection of semiconductor devices from alpha-particles. The product comprises a heat resistant support film, a pressure sensitive adhesive layer on one side of the support film, a least one alpha-particle protector member formed of a plastic material capable of protecting the semiconductor device releasably supported on the pressure sensitive adhesive, and a layer of heat resistant adhesive bonded to the plastic material on its side lying opposite to the side bonded to the pressure sensitive adhesive. Preferably, a primer layer lies between the heat resistant support film on the pressure sensitive adhesive to insure that clean removal of the support film and pressure sensitive adhesive from the surface of the alpha-particle protector member. In order to aid in this removal the surface of the alpha-particle protector member facing the pressure sensitive layer is also coated with a release coating. The product is used by bonding the heat
http://www.google.com/patents/US4761335?dq=mezick
N-Succinimidyl iodoacetate (SIA)  N-Succinimidyl iodoacetate (SIA)
SIA crosslinker is a non-cleavable, heterobifunctional protein crosslinker. SIA crosslinking reagent is the shortest amine and sulfhydryl (thiol) reactive protein crosslinker.
http://www.proteochem.com/heterobifunctionalcrosslinkerssia-c-1_7_77.html
Bismuth-214 | Bi - PubChem  Bismuth-214 | Bi - PubChem
Bismuth-214 | Bi | CID 6328549 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/6328549
MUCI - What does MUCI stand for? The Free Dictionary  MUCI - What does MUCI stand for? The Free Dictionary
Looking for online definition of MUCI or what MUCI stands for? MUCI is listed in the Worlds largest and most authoritative dictionary database of abbreviations and acronyms
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Huidu e cam sarac  Huidu e cam sarac
Succesul - Cum sa zic ca nu am succes? Succesul meu e masurat in mai multe procese de simpatie, de ore nedormite si extraordinar de multe procese de invidie. Doar traim in Romania. InvidiaUite, a murit un moment de invidie. Am facut muci...
http://www.9am.ro/stiri-revista-presei/LifeStar/427/Huidu-e-cam-sarac.html
JETP Letters V. 66, I .02  JETP Letters V. 66, I .02
JETP Letters -- July 25, 1997 Volume 66, Issue 2, pp. 75-131 The contribution of the (t(tau) + N) component to the alpha-particle wave function from data on the reactions p(alpha,pp)t and p(alpha,pn)tau at incident alpha-particle momentum 5 GeV/c M. V. Chadeyeva, V. E. Grechko, V. V. Solovev, and V. F. Turov Full Text: PDF (133 kB) How can we study the halo momentum distribution in exotic nuclei? G. D. Alkhazov Full Text: PDF (61 kB) Measurement of the 45Ca beta spectrum in search of deviations from the theoretical shape A. V. Derbin, A. I. Egorov, S. V. Bakhlanov, and V. N. Muratova Full Text: PDF (77 kB) Liouville theory on a ZN Riemann surface S. A. Apikyan Full Text: PDF (111 kB) Shock wave structure in dense gases V. V. Zhakhovskii, K. Nishihara, and S. I. Anisimov Full Text: PDF (97 kB) Observation of the two-photon photoelectric effect in low-intensity optical fields during photostimulated fractal aggregation of colloidal silver S. V. Karpov, A. K. Popov, and V. V. Slabko Full Text: PDF ...
https://dspace.sunyconnect.suny.edu/handle/1951/36962?show=full
New Black Voter and Obamas Presidential Campaign - Oxford...  "New Black Voter" and Obama's Presidential Campaign - Oxford...
The chapter uses data from the 2008 American National Election Studies (ANES) time series to examine symbolic empowerment and its impact on political behavior. The chapter reveals that voting in the nomination campaign-specifically, voting for the winning candidate-encouraged other forms of participation on the part of the African American electorate comprised of the newly registered and those previously registered who were similarly energized by Obamas historic candidacy. Newcomer or not, African Americans were more likely to participate in all types of political behavior-including wearing campaign buttons, posting a lawn sign or bumper sticker, engaging in political talk for or against a candidate, donating money to the Democratic Party, and attending a speech or rally-in part because of the salience of racial group identification.
http://www.oxfordscholarship.com/view/10.1093/acprof:oso/9780199314171.001.0001/acprof-9780199314171-chapter-5
Surgery center setup  Surgery center setup
Call pts the night before. Surgery time is 0700, usually get pt into room at 0715-0725. Usual preop is famotidine 40, metoclopramide 10, clonidine 0.2 or 0.3, bicitra 30cc, given automatically. Sylvia will ask how much clonidine. You may modify any of this, of course. Anes machine is older Ohmeda with manual and separate APL…
https://dejswa.wordpress.com/2015/06/30/surgery-center-setup/
Search Articles | University of Toronto Libraries  Search Articles | University of Toronto Libraries
by Bellani, Giacomo and Laffey, John G and Pham, Tài and Madotto, Fabiana and Fan, Eddy and Brochard, Laurent and Esteban, Anes and Gattinoni, Luciano and Bumbasirevic, Vesna and Piquilloud, Lise and van Haren, Frank and Larsson, Anders and McAuley, Daniel F and Bauer, Philippe R and Arabi, Yaseen M and Ranieri, Marco and Antonelli, Massimo and Rubenfeld, Gordon D and Thompson, B. Taylor and Wrigge, Hermann and Slutsky, Arthur S and Pesenti, Antonio and Rios, Fernando and Sottiaux, T and Depuydt, p and Lora, Fredy S and Azevedo, Luciano Cesar and Bugedo, Guillermo and Qiu, Haibo and Gonzalez, Marcos and Silesky, Juan and Cerny, Vladimir and Nielsen, Jonas and Jibaja, Manuel and Matamis, Dimitrios and Ranero, Jorge Luis and Amin, Pravin and Hashemian, S. M and Clarkson, Kevin and Kurahashi, Kiyoyasu and Villagomez, Asisclo and Zeggwagh, Amine Ali and Heunks, Leo M and Laake, Jon Henrik and Palo, Jose Emmanuel and do Vale Fernandes, Antero and Sandesc, Dorel and Arabi, Yaasen and Bumbasierevic, ...
https://query.library.utoronto.ca/index.php/search/q?kw=Author:Ogino,%20Hiroyuki
tubely.ro: Muci design  tubely.ro: Muci design
Acest site este un pamflet ! Nu ne asumam nici o raspundere in ceea ce priveste continutul materialelor prezente pe acest site si nici nu consideram ca incalca in vreun fel drepturile de autor avand in vedere faptul ca se considera a fi informatii publice atata vreme cat sunt culese de pe site-uri publice care nu specifica intr-un mod expres ca ar fi proprietatea cuiva.Daca te regasesti intr-una din imaginile de pe site si doresti in mod expres ca acestea sa fie scoase , poti lua legatura cu administratorul site-ului facand dovada ca esti protagonistul materialului respectiv . Materialele prezentate pe acest site sunt in totalitate primite de la vizitatorii acestui site care isi asuma intreaga responsabilitate asupra lor sau al continutului lor! Pentru nici una dintre situatii autorii acestui site nu pot fi acuzati de nimic si nici nu se considera responsabili de ceva anume! Daca iti place ceva anume si preiei de pe site , ai macar bunul simt si specifica prin link sursa ...
http://tubely-ro.blogspot.com/2010/04/muci-design.html
Ščipalki za nohte, muci  Ščipalki za nohte, muci
Ščipalki za nohte Kikkerland imate lahko vedno pri roki. Ena ščipalka je namenjena krajšanju nohtov na rokah, druga pa na nogah. Na notranji strani ščipalke je pilica za nohte. Rezilo ščipalk je ravno, kar zagotavlja, da se postriženi nohti ne vrastejo.
https://1001dar.si/review/product/list/id/22466/category/226/
The best Side of tattooing eye makeup - Blog  The best Side of tattooing eye makeup - Blog
The method allows women who definitely have discolored or lightened areolas just after breastfeeding or clients which have experienced areola graft surgical treatment. People with pores and skin discoloration Problems (e.g. Vitiligo) may gain from areola tattooing. Also, people who have not experienced breast surgical procedures but are self-mindful about their areola shade or dimension (also gentle or also small) may possibly decide on this method to adjust their physical appearance. Waiting and Preparing For Your Treatment Areola simulation or scar camouflage could be performed when your medical professional approves it. Dr. Reed openly communicates with her clients surgeons and she or he follows all recommendations made by tattooing lips permanent makeup them. Scar camouflage can usually be done once six months soon after operation, but you need to very first question your medical doctor. When you have been cleared for areola tattooing, you are able to timetable your session with Dr. Reed. ...
http://devinnixsh.ampblogs.com
Bismuth-209 - Offline Wikipedia  Bismuth-209 - Offline Wikipedia
Due to its extraordinarily long half-life, for nearly all applications 209Bi can still be treated as if it were non-radioactive. Although 209Bi holds the half-life record for alpha decay, bismuth does not have the longest half-life of any radionuclide to be found experimentally-this distinction belongs to tellurium-128 (128Te) with a half-life estimated at 7.7 × 1024 years by double β-decay (double beta decay).[5]. The half-life value of bismuth-209 was confirmed in 2012 by an Italian team in Gran Sasso who reported (2.01±8)×1019 years, and an even longer half-life, for bismuth-209 alpha decay to the first excited state of thalium-205 at 204 keV, was estimated to be 1.66×1021 years.[6] Even though this value is shorter than the measured half-life of tellurium-128, both alpha decays of bismuth-209 hold the record of the thinnest natural line widths of any measurable physical excitation, estimated respectively at ΔΕ~5.5×10−43 eV and ΔΕ~1.3×10−44 eV in application of the uncertainty ...
http://wiki-offline.jakearchibald.com/wiki/Bismuth-209
The process of ionization of argon by alpha-particles - CaltechTHESIS  The process of ionization of argon by alpha-particles - CaltechTHESIS
To ionize an atom of any element requires the expenditure of a certain amount of work, dependent upon the particular element concerned. This energy may be acquired through impact with a rapidly moving electron, positive ion, or neutral atom, or through absorption of radiation. We shall be concerned with ionization by the impact of positive ions and [alpha]-particles. Suppose the colliding particle has more than sufficient energy to affect the removal of one electron, what is the net result of the collision? May it happen under certain favourable conditions that a second electron is removed, or does the ionization process invariably consist in the removal of a single electron? It was the object of this research to supply further experimental proof for the theory that more than one electron may be dislodged by single impact. Up until 1911 we had no unambiguous information as to what really happens when a high speed particle collides with a normal atom. It was not known with certainty whether one ...
https://thesis.library.caltech.edu/4401/
heart value replacement advised - cured with C/Vit. K - Page 3 - Vitamin C Forum  heart value replacement advised - cured with C/Vit. K - Page 3 - Vitamin C Forum
Your dentist could use a technique called lingual infiltration w/ the local anes. called Articaine. Usually works on my patients, or one of the alternative sites for anesthesia. Most herbal medicines do not work for tooth pain unless the nerve is exposed. If it is only decay, get the decay out and place a bonded filling or crown. If the nerve is involved, root canal or ext. It appears that many here are against root canals, but they are a viable treatment if done well. If a person continues to have problems then extract it and put in an implant ...
http://vitaminc.foundation/forum/viewtopic.php?f=11&t=6207&sid=ab4357c0e937b358e6e10f4a1767bbbd&start=30
Quotes from the book no longer at ease  Quotes from the book no longer at ease
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http://hastati.tk/quotes-from-the-book-no-longer-at-ease
Lo blòg deu Joan: dagost 2013  Lo blòg deu Joan: d'agost 2013
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http://loblogdeujoan.blogspot.com/2013/08/
Iz moje kuhinje: Knedle s šljivama-okruglice os šljiva  Iz moje kuhinje: Knedle s šljivama-okruglice os šljiva
LOKARDE S POVRCEM IZ PECNICE Ako vas muci przenje,pecenje ribe u stanu,ako mrzite sto vam od plave ribe/koja je zdrava,ukusna i jeftina/cije ...
http://kolaci-recepti.blogspot.com/2008/07/knedle-s-sljivama-okruglice-os-sljiva_31.html
Alpha-emitting particles in lungs: Recommendations of the National Council on Radiation Protection and Measurements (NCRP...  Alpha-emitting particles in lungs: Recommendations of the National Council on Radiation Protection and Measurements (NCRP...
Tags: Alpha-emitting particles in lungs: Recommendations of the National Council on Radiation Protection and Measurements (NCRP report ; no. 46), PDF EBooks, download online, epub files, books online, pdf epub books, download Now, Alpha-emitting particles in lungs: Recommendations of the National Council on Radiation Protection and Measurements (NCRP report ; no. 46), free Online download, ebook online free read and download, Alpha-emitting particles in lungs: Recommendations of the National Council on Radiation Protection and Measurements (NCRP report ; no. 46), pdf file, epub download free, online download, mega upload.. ...
http://ik.poetical.biz/3yymy.html
Transmission dynamics of gram-negative bacterial pathogens in the anes by Randy W. Loftus, Jeremiah R. Brown et al.  "Transmission dynamics of gram-negative bacterial pathogens in the anes" by Randy W. Loftus, Jeremiah R. Brown et al.
BACKGROUND: Gram-negative organisms are a major health care concern with increasing prevalence of infection and community spread. Our primary aim was to characterize the transmission dynamics of frequently encountered gram-negative bacteria in the anesthesia work area environment (AWE). Our secondary aim was to examine links between these transmission events and 30-day postoperative health care-associated infections (HCAIs). METHODS: Gram-negative isolates obtained from the AWE (patient nasopharynx and axilla, anesthesia provider hands, and the adjustable pressure-limiting valve and agent dial of the anesthesia machine) at 3 major academic medical centers were identified as possible intraoperative bacterial transmission events by class of pathogen, temporal association, and phenotypic analysis (analytical profile indexing). The top 5 frequently encountered genera were subjected to antibiotic disk diffusion sensitivity to identify epidemiologically related transmission events. Complete multivariable
https://escholarship.umassmed.edu/anesthesiology_pubs/171/
The Old North State :: North Carolina Newspaper Digitization Project  The Old North State :: North Carolina Newspaper Digitization Project
vol iv , sarjslsiiily n c march 12 hm no 10 tjjeodl&nartl state ptmi.ihiir.il wi iki.v nv x xi w i s xi anes editor and proprii tor rates ol m iighiption okb vllaii pay ihle in a lvalue 3.00 six mum us " " 1.50 ft copies to on address 12,30 rates of ad i rtisintf one square first insertion f 1 1 ii i each additional insert 1 50 - of levvii i 1 inch sj iie.b e.idiliiin oilesi colisl llule a square special dotlcos m ill be oharged rin per cent higher than tho above rates courl orders six ivoelts 7 if tl ash nc eoinpuiiius tl rtlor 10 if it does not obituary notices over six lines charged as advertisements to persons w ishing to a ken ,-â- for a lon ger timo than ono month the most liberal terms will bu gl en uow it was 8weetjaaonio all natures so loroly to-n li the eurlh is s parolli i iu raiments ol light and the heavens nre beaming an 1 blue ; the breezes aro sporting among lho ; bowers the moonlights coquetting tbo dew il ami lowejfl the nlghtingali inu u is lonting in showers â€" ...
http://digital.ncdcr.gov/cdm/compoundobject/collection/p15016coll1/id/16682/rec/5
DiVA - Search result  DiVA - Search result
A series of analytic and numerical models have been developed for the prediction and interpretation of the energy spectrum of the neutron emission from thermonuclear deuteriumtritium (DT) plasmas. The main component of the neutron emission, due to reactions between thermal fuel ions, has been modeled as well as minority components due to the presence of fast (supra-thermal) ions. In particular, the so-called alpha-particle knock-on neutron (AKN) emission has been analyzed and found to carry information on the con- finement of fast alpha particles inside the plasma. The alpha particles carry one fifth of the fusion power generated in the plasma and provide the plasma self-heating. This thesis is devoted to this central endeavor of fusion research and the possibilities for its study in todays largest magnetic confinement devices, the tokamaks.. The developed models have been used for the interpretation of experimental data taken during the first deuterium-tritium experiment (DTE1) at the Joint ...
http://uu.diva-portal.org/smash/resultList.jsf?af=%5B%5D&aq=%5B%5B%7B%22organisationId%22%3A%221059%22%7D%5D%5D&aqe=%5B%5D&aq2=%5B%5B%5D%5D&language=en&query=
Fadel Muci - GrabCAD  Fadel Muci - GrabCAD
Develop great products faster with 3D printing solutions, free CAD models, and access to the worlds largest community of engineers, designers and
https://grabcad.com/fadel.muci-1
ANES110-0917: Wild Adventures: Anesthesia and Analgesia in Wildlife - Continual Education - VSPN  ANES110-0917: Wild Adventures: Anesthesia and Analgesia in Wildlife - Continual Education - VSPN
Heather Wilson Barron is Hospital Director at the Clinic for Rehabilitation of Wildlife (CROW) on Sanibel Island, FL. She received training in exotic and wild animal medicine and surgery through a residency at the University of Georgia, College of Veterinary Medicine, where she stayed on as faculty in the Zoological Medicine Service for a decade. She obtained further international experience as Department Head of Clinical Medicine at St. Matthews University, School of Veterinary Medicine in the Cayman Islands, where she was also the veterinarian for the Cayman Turtle Farm and Cayman Wildlife Rescue. She has served as a consultant for IDEXX and Antech Imaging Services and is a former president of the Association of Avian Veterinarians. Michelle Hawkins received her veterinary degree from the University of Pennsylvania in 1997. She completed a residency and fellowship in Companion Avian and Exotic Animal Medicine and Surgery at the University of California, Davis in 2001. After 2 years in private ...
http://www.vin.com/ce/ANES110-0917_VSPN.htm
501 Readings Week 4 - BluWiki - 2018 Bluwiki  501 Readings Week 4 - BluWiki - 2018 Bluwiki
Cook, Elizabeth Adell. 1989. "Measuring Feminist Conciousness." Women and Politics 9:71-88 Cook asserts that the previous measures of feminist consciousness in the literature are inadequate as they contain problems of continuity and validity, and offers her own measure of feminist consciousness that can be used in all American National Election Studies. She defines group consciousness as a "politicized identification with a group of which one is an objective member and implies an orientation toward collective action to achieve the groups goals" (71) and argues that previous researchers attempts to operationalize "group consciousness" in terms of the ANES has been unsuccessful. Cook contends that combining the feeling thermometer for the womens liberation movement with the equal role scale will allow for the greatest external validity because "patterns of relationships between demographic variables and the proposed measure of feminist consciousness" are consistent with previous literature ...
http://bluwiki.com/go/501_Readings_Week_4
P ramesh babu digital signal processing free download  P ramesh babu digital signal processing free download
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http://2tamil.tk/p-ramesh-babu-digital-signal-processing-free-download
BfS - Accredited calibration laboratory  BfS - Accredited calibration laboratory
For this purpose the air of the reference atmosphere is conveyed with a constant volume flow rate through a combined mesh-filter probe. The fraction of the short-lived radon-222 progenies, which are attached to aerosols, are deposited to the filter. The free (unattached) fraction is adsorbed to the wire mesh.. The activity collected at the filter and the mesh, respectively, decays according to the radioactive decay law. The activities of the alpha-emitting nuclides are measured in periodic time intervals. The associated graphic representation is denominated as decay curve.. Immediately after sampling the decay curves of the filter and mesh alpha activity are measured, respectively. An algorithm is used to deduce the potential alpha-energy concentration and unattached part of the short-lived radon-222 progenies. ...
http://www.bfs.de/EN/topics/ion/service/radon-measurement/calibration-laboratory/calibration-laboratory_node.html
Muci 5530+55003 | WS Bath Collections  Muci 5530+55003 | WS Bath Collections
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser. ...
https://www.wsbathcollections.com/muci-5530-55003
Iz moje kuhinje: Lemon cake  Iz moje kuhinje: Lemon cake
LOKARDE S POVRCEM IZ PECNICE Ako vas muci przenje,pecenje ribe u stanu,ako mrzite sto vam od plave ribe/koja je zdrava,ukusna i jeftina/cije ...
http://kolaci-recepti.blogspot.com/2012/01/lemon-cake.html
AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureHumanitiesInformation ScienceNamed GroupsHealth CarePublication CharacteristicsGeographicals
AstatineScandiumMetals, Alkaline EarthViral StructuresElementsLawrenciumRadiumFranciumMedicine in LiteratureLiterature, ModernScienceForeheadFamous PersonsDramaRNA HelicasesDictionaries, MedicalDictionaries as TopicDictionaries, ChemicalTerminology as TopicPhoneticsDictionaryDictionaries, PharmaceuticSiliconDiet FadsBooksKetogenic DietShoesBook SelectionCarisoprodolMeprobamateMuscle Relaxants, CentralBemegrideSomatosensory DisordersToe JointHistory, 15th CenturyFloridaComputer SecuritySingaporeWhiplash InjuriesBeta ParticlesPatents as TopicMetalsIsotopesIsotope LabelingCoronary RestenosisStentsChlorineChemical IndustryTransition TemperatureChlorine CompoundsHazardous SubstancesDisinfectantsChloramines
Radon - Simple English Wikipedia, the free encyclopediaRadon - Simple English Wikipedia, the free encyclopedia
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ...
Chlór - WikipédiaChlór - Wikipédia
Kapitola Chlorine, Bromine, Iodine, & Astatine: Inorganic Chemistry. (po anglicky). *↑ a b c d e f g h i j k l m n o p q ... Kapitola The Halogens: Fluorine, Chlorine, Bromine, Iodine and Astatine, s. 789-887. (po anglicky). ...
CaesiumCaesium
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ...
ഓഗനെസൺ - വിക്കിപീഡിയഓഗനെസൺ - വിക്കിപീഡിയ
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ...
Post-transition metalPost-transition metal
... astatine was predicted to be a monatomic metal, with a face-centered cubic crystalline structure.[177] As such, astatine could ... Astatine oxyanions AtO−, AtO−. 3 and AtO−. 4 are known,[182] oxyanion formation being a tendency of nonmetals.[183] The ... Kugler HK & Keller C (eds) 1985, Gmelin Handbook of Inorganic and Organometallic chemistry, 8th ed., 'At, Astatine', system no ... Hawkes SJ 2010, 'Polonium and Astatine are not Semimetals', Journal of Chemical Education, vol. 87, no. 8, p. 783, doi:10.1021 ...
Standard atomic weightStandard atomic weight
Asta-tine85At​[210] Radon86Rn​[222] 7 Fran-cium87Fr​[223] Ra-dium88Ra​[226] Actin-ium89Ac​[227] Ruther-fordium104Rf​[267] Dub- ...
Portal:ChemistryPortal:Chemistry
Asta-tine85At​[210] Radon86Rn​[222] 7 Fran-cium87Fr​[223] Ra-dium88Ra​[226] Actin-ium89Ac​[227] Ruther-fordium104Rf​[267] Dub- ...
Timeline of chemical element discoveriesTimeline of chemical element discoveries
"85 Astatine". Elements.vanderkrogt.net. Retrieved 2008-09-12.. *^ Close, Frank E. (2004). Particle Physics: A Very Short ... Astatine 1940 R. Corson, R. MacKenzie and E. Segrè Obtained by bombarding bismuth with alpha particles.[135] Later determined ... astatine, and promethium) were eventually found in trace amounts in nature as well.[133] ...
Template:Infobox element/symbol-to-top-image/doc - Simple English Wikipedia, the free encyclopediaTemplate:Infobox element/symbol-to-top-image/doc - Simple English Wikipedia, the free encyclopedia
Alt: Quartz vial (9 mm diameter) containing ~300 micrograms of solid 253Es. The illumination produced is a result of the intense radiation from 253Es ...
थॅलियम - विकिपीडियाथॅलियम - विकिपीडिया
आवाज महाराष्ट्राचा न्यूज चैनलAstatine,Astatine]] [[ आवाज महाराष्ट्राचा न्यूज चैनलRadon,Radon]] [[ आवाज महाराष्ट्राचा न्यूज ...
ഫലകം:Infobox scandium - വിക്കിപീഡിയഫലകം:Infobox scandium - വിക്കിപീഡിയ
Astatine,Astatine [[Radon,Radon [[Francium,Francium [[Radium,Radium [[Actinium,Actinium [[Thorium,Thorium [[Protactinium, ...
Alkaline earth metalAlkaline earth metal
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ...
آرگون - ویکی‌پدیا، دانشنامهٔ آزادآرگون - ویکی‌پدیا، دانشنامهٔ آزاد
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ...
പ്രതീകം (രസതന്ത്രം) - വിക്കിപീഡിയപ്രതീകം (രസതന്ത്രം) - വിക്കിപീഡിയ
Astatine. the Greek astatos, 'unstable'. 17. 6. [210][upper-roman 10]. 7. 575. 610. -. 2.2. 3×10−20[upper-roman 11] ...
Radon-222Radon-222
Fry, C.; Thoennessen, M. (2013). "Discovery of the astatine, radon, francium, and radium isotopes". Atomic Data and Nuclear ...
FranciumFrancium
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ... The only comparable element is astatine, whose most stable natural isotope, astatine-219 (the alpha daughter of francium-223), ... after astatine). The isotopes of francium decay quickly into astatine, radium, and radon. The electronic structure of a ... Astatine, and Francium. Translated by R. Kondor. Ann Arbor-Humphrey Science Publishers. p. 269. ISBN 978-0-250-39923-9. .. .mw- ...
Decay chainDecay chain
... astatine, bismuth, francium, lead, polonium, protactinium, radium, radon, thallium, and thorium. All are present, at least ... astatine, bismuth, lead, polonium, protactinium, radium, radon, thallium, and thorium. All are present, at least transiently, ... astatine, bismuth, francium, lead, polonium, protactinium, radium, thallium, thorium, and uranium. Since this series was only ...
ഫലകം:Infobox titanium - വിക്കിപീഡിയഫലകം:Infobox titanium - വിക്കിപീഡിയ
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ...
Group 3 elementGroup 3 element
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ...
Alkali metalAlkali metal
Astatine Radon Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium ... and astatine), forming salts known as the alkali metal halides. The reaction is very vigorous and can sometimes result in ... because of the great instability and rarity of astatine and francium. The most well-known of the twenty is certainly sodium ...
మూస:Extended periodic table (by Fricke, 52 columns, large cells) - వికీపీడియామూస:Extended periodic table (by Fricke, 52 columns, large cells) - వికీపీడియా
Astatine 85. At. [210] isotopes Radon 86. Rn. [222] isotopes 7 Francium 87. Fr. [223] isotopes Radium 88. Ra. [226] isotopes ...
প্রতীকের ভিত্তিতে মৌলসমূহের তালিকা - উইকিপিডিয়াপ্রতীকের ভিত্তিতে মৌলসমূহের তালিকা - উইকিপিডিয়া
Discredited claim to discovery of astatine.. [৭] Am. Alabamium. 85. Discredited claim to discovery of astatine.. [৭] ...
ऐक्टिनाइड - विकिपीडियाऐक्टिनाइड - विकिपीडिया
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Define -ine. -ine synonyms, -ine pronunciation, -ine translation, English dictionary definition of -ine. suff. 1. Of or relating to: Benedictine. 2. Made of; resembling: opaline. suff. 1. also -in A chemical substance, especially: a. Halogen: bromine. b.
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