Blood Circulation: The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.Extracorporeal Circulation: Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation.Pulmonary Circulation: The circulation of the BLOOD through the LUNGS.Collateral Circulation: Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.Enterohepatic Circulation: Recycling through liver by excretion in bile, reabsorption from intestines (INTESTINAL REABSORPTION) into portal circulation, passage back into liver, and re-excretion in bile.Coronary Circulation: The circulation of blood through the CORONARY VESSELS of the HEART.Cerebrovascular Circulation: The circulation of blood through the BLOOD VESSELS of the BRAIN.Placental Circulation: The circulation of BLOOD, of both the mother and the FETUS, through the PLACENTA.Splanchnic Circulation: The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.Blood Circulation Time: Determination of the shortest time interval between the injection of a substance in the vein and its arrival at some distant site in sufficient concentration to produce a recognizable end result. It represents approximately the inverse of the average velocity of blood flow between two points.Liver Circulation: The circulation of BLOOD through the LIVER.Regional Blood Flow: The flow of BLOOD through or around an organ or region of the body.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Vascular Resistance: The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Cross Circulation: The circulation in a portion of the body of one individual of blood supplied from another individual.Assisted Circulation: Pumping that aids the natural activity of the heart. (Dorland, 27th ed)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.Renal Circulation: The circulation of the BLOOD through the vessels of the KIDNEY.Cardiopulmonary Resuscitation: The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.Pulmonary Artery: The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Placenta: A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).Maternal-Fetal Exchange: Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission.Metabolic Clearance Rate: Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.Vasodilation: The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Laser-Doppler Flowmetry: A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Vertebrobasilar Insufficiency: Localized or diffuse reduction in blood flow through the vertebrobasilar arterial system, which supplies the BRAIN STEM; CEREBELLUM; OCCIPITAL LOBE; medial TEMPORAL LOBE; and THALAMUS. Characteristic clinical features include SYNCOPE; lightheadedness; visual disturbances; and VERTIGO. BRAIN STEM INFARCTIONS or other BRAIN INFARCTION may be associated.Veins: The vessels carrying blood away from the capillary beds.Vasoconstriction: The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.Microcirculation: The circulation of the BLOOD through the MICROVASCULAR NETWORK.Fontan Procedure: A procedure in which total right atrial or total caval blood flow is channeled directly into the pulmonary artery or into a small right ventricle that serves only as a conduit. The principal congenital malformations for which this operation is useful are TRICUSPID ATRESIA and single ventricle with pulmonary stenosis.Fetus: The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.Arteries: The vessels carrying blood away from the heart.Half-Life: The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.Cerebral Arteries: The arterial blood vessels supplying the CEREBRUM.Cardiac Output: The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Vasodilator Agents: Drugs used to cause dilation of the blood vessels.Portal System: A system of vessels in which blood, after passing through one capillary bed, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Oxygen: An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.Bronchial Arteries: Left bronchial arteries arise from the thoracic aorta, the right from the first aortic intercostal or the upper left bronchial artery; they supply the bronchi and the lower trachea.Sheep: Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Cerebral Angiography: Radiography of the vascular system of the brain after injection of a contrast medium.Coronary Vessels: The veins and arteries of the HEART.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Polyethylene Glycols: Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.Blood Vessels: Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).Endothelium, Vascular: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.Pulsatile Flow: Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.Retinal Artery: Central retinal artery and its branches. It arises from the ophthalmic artery, pierces the optic nerve and runs through its center, enters the eye through the porus opticus and branches to supply the retina.Erythrocytes: Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.Vertebral Artery: The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Bile: An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Basilar Artery: The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.Anoxia: Relatively complete absence of oxygen in one or more tissues.Carbon Dioxide: A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.Blood Volume: Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.Drug Carriers: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.Parabiosis: The experimental joining of two individuals for the purpose of studying the effects of one on the other.Liposomes: Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.Bile Acids and Salts: Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Retinal Vessels: The blood vessels which supply and drain the RETINA.Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Mice, Inbred C57BLSerum Albumin, Radio-Iodinated: Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of 8 days, and emits beta and gamma rays. It is used as a diagnostic aid in blood volume determination. (from Merck Index, 11th ed)Oxygen Consumption: The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)Persistent Fetal Circulation Syndrome: A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.Choroid: The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Partial Pressure: The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Injections, Intra-Arterial: Delivery of drugs into an artery.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Venous Pressure: The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.Ductus Arteriosus: A fetal blood vessel connecting the pulmonary artery with the descending aorta.Papio: A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.Hypothermia, Induced: Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Erythrocyte Aging: The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days.Umbilical Arteries: Specialized arterial vessels in the umbilical cord. They carry waste and deoxygenated blood from the FETUS to the mother via the PLACENTA. In humans, there are usually two umbilical arteries but sometimes one.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Infarction, Posterior Cerebral Artery: NECROSIS induced by ISCHEMIA in the POSTERIOR CEREBRAL ARTERY distribution system which supplies portions of the BRAIN STEM; the THALAMUS; TEMPORAL LOBE, and OCCIPITAL LOBE. Depending on the size and location of infarction, clinical features include OLFACTION DISORDERS and visual problems (AGNOSIA; ALEXIA; HEMIANOPSIA).Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Angiography: Radiography of blood vessels after injection of a contrast medium.Portal Pressure: The venous pressure measured in the PORTAL VEIN.Heart: The hollow, muscular organ that maintains the circulation of the blood.Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.Vasomotor System: The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.Kinetics: The rate dynamics in chemical or physical systems.Capillaries: The minute vessels that connect the arterioles and venules.Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.Ultrasonography, Doppler: Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)Lymphatic System: A system of organs and tissues that process and transport immune cells and LYMPH.Out-of-Hospital Cardiac Arrest: Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.Middle Cerebral Artery: The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.Vasoconstrictor Agents: Drugs used to cause constriction of the blood vessels.Lymph: The interstitial fluid that is in the LYMPHATIC SYSTEM.Posterior Cerebral Artery: Artery formed by the bifurcation of the BASILAR ARTERY. Branches of the posterior cerebral artery supply portions of the OCCIPITAL LOBE; PARIETAL LOBE; inferior temporal gyrus, brainstem, and CHOROID PLEXUS.Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Blood Gas Analysis: Measurement of oxygen and carbon dioxide in the blood.Antigen-Antibody Complex: The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.Cardiovascular System: The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.Rats, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.Hematocrit: The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.Iodine Radioisotopes: Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.Ultrasonography, Doppler, Transcranial: A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.Ophthalmic Artery: Artery originating from the internal carotid artery and distributing to the eye, orbit and adjacent facial structures.Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.Infant, Newborn: An infant during the first month after birth.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Jugular Veins: Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.Arterioles: The smallest divisions of the arteries located between the muscular arteries and the capillaries.Pia Mater: The innermost layer of the three meninges covering the brain and spinal cord. It is the fine vascular membrane that lies under the ARACHNOID and the DURA MATER.Mononuclear Phagocyte System: Mononuclear cells with pronounced phagocytic ability that are distributed extensively in lymphoid and other organs. It includes MACROPHAGES and their precursors; PHAGOCYTES; KUPFFER CELLS; HISTIOCYTES; DENDRITIC CELLS; LANGERHANS CELLS; and MICROGLIA. The term mononuclear phagocyte system has replaced the former reticuloendothelial system, which also included less active phagocytic cells such as fibroblasts and endothelial cells. (From Illustrated Dictionary of Immunology, 2d ed.)Gestational Age: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.Intestines: The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.Water Movements: The flow of water in enviromental bodies of water such as rivers, oceans, water supplies, aquariums, etc. It includes currents, tides, and waves.Endothelial Cells: Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.Heart-Lung Machine: Apparatus that provides mechanical circulatory support during open-heart surgery, by passing the heart to facilitate surgery on the organ. The basic function of the machine is to oxygenate the body's venous supply of blood and then pump it back into the arterial system. The machine also provides intracardiac suction, filtration, and temperature control. Some of the more important components of these machines include pumps, oxygenators, temperature regulators, and filters. (UMDNS, 1999)Yolk Sac: The first of four extra-embryonic membranes to form during EMBRYOGENESIS. In REPTILES and BIRDS, it arises from endoderm and mesoderm to incorporate the EGG YOLK into the DIGESTIVE TRACT for nourishing the embryo. In placental MAMMALS, its nutritional function is vestigial; however, it is the source of INTESTINAL MUCOSA; BLOOD CELLS; and GERM CELLS. It is sometimes called the vitelline sac, which should not be confused with the VITELLINE MEMBRANE of the egg.Spleen: An encapsulated lymphatic organ through which venous blood filters.Microspheres: Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.Homeostasis: The processes whereby the internal environment of an organism tends to remain balanced and stable.Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Forearm: Part of the arm in humans and primates extending from the ELBOW to the WRIST.Embolism, Air: Blocking of a blood vessel by air bubbles that enter the circulatory system, usually after TRAUMA; surgical procedures, or changes in atmospheric pressure.Reference Values: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.Angiography, Digital Subtraction: A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.Heart, Artificial: A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Air Movements: The motion of air currents.Femoral Artery: The main artery of the thigh, a continuation of the external iliac artery.Heart Bypass, Right: Diversion of the flow of blood from the entrance to the right atrium directly to the pulmonary arteries, avoiding the right atrium and right ventricle (Dorland, 28th ed). This a permanent procedure often performed to bypass a congenitally deformed right atrium or right ventricle.Capillary Permeability: The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Arteriovenous Anastomosis: A vessel that directly interconnects an artery and a vein, and that acts as a shunt to bypass the capillary bed. Not to be confused with surgical anastomosis, nor with arteriovenous fistula.Oxygenators: Devices which mechanically oxygenate venous blood extracorporeally. They are used in combination with one or more pumps for maintaining circulation during open heart surgery and for assisting the circulation in patients seriously ill with some cardiac and pulmonary disorders. (UMDNS, 1999)Constriction: The act of constricting.Acute Disease: Disease having a short and relatively severe course.Acetylcholine: A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.Ultrasonography, Doppler, Pulsed: Ultrasonography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.Indocyanine Green: A tricarbocyanine dye that is used diagnostically in liver function tests and to determine blood volume and cardiac output.Nitroprusside: A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.Biological Transport: The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Carotid Artery, Internal: Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.Resuscitation: The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)Rheology: The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.Nitric Oxide Synthase: An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.Hemorheology: The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.Capillary Resistance: The vascular resistance to the flow of BLOOD through the CAPILLARIES portions of the peripheral vascular bed.Infarction, Anterior Cerebral Artery: NECROSIS occurring in the ANTERIOR CEREBRAL ARTERY system, including branches such as Heubner's artery. These arteries supply blood to the medial and superior parts of the CEREBRAL HEMISPHERE, Infarction in the anterior cerebral artery usually results in sensory and motor impairment in the lower body.Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.Fetal Blood: Blood of the fetus. Exchange of nutrients and waste between the fetal and maternal blood occurs via the PLACENTA. The cord blood is blood contained in the umbilical vessels (UMBILICAL CORD) at the time of delivery.Intestinal Absorption: Uptake of substances through the lining of the INTESTINES.Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Aorta: The main trunk of the systemic arteries.Leukocyte Count: The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.Neoplastic Cells, Circulating: Exfoliate neoplastic cells circulating in the blood and associated with metastasizing tumors.Asphyxia: A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Nanoparticles: Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.History, 17th Century: Time period from 1601 through 1700 of the common era.Hemoglobins: The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Ligation: Application of a ligature to tie a vessel or strangulate a part.Mice, Inbred BALB CErythrocyte Count: The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.Compliance: Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.Carotid Arteries: Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Respiration: The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Anterior Cerebral Artery: Artery formed by the bifurcation of the internal carotid artery (CAROTID ARTERY, INTERNAL). Branches of the anterior cerebral artery supply the CAUDATE NUCLEUS; INTERNAL CAPSULE; PUTAMEN; SEPTAL NUCLEI; GYRUS CINGULI; and surfaces of the FRONTAL LOBE and PARIETAL LOBE.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.

Intraaortic balloon pumping assist following open heart surgery for coronary artery disease. (1/79)

Intraaortic balloon pump (IABP) assist was employed in 36 patients after surgical operation for coronary artery disease. In 31 patients, the aid of IABP was required because cardiopulmonary bypass could not be terminated without it. In three of these patients, IABP assist was started before the surgical procedure because these patients were in cardiogenic shock due to myocardial infarction. In the remaining five patients, IABP assist was applied for refractory cardiogenic shock in the early postoperative period. The overall survival rate was 58 percent. IABP assist was used in 13 patients with an ejection fraction of 0.1 to 0.2 (normal 0.7). Nine of these patients survived. From our experience, it would appear that this temporary mechanical circulatory support provides a significant advantage in saving patients who might otherwise die after surgical procedures involving the coronary artery.  (+info)

Effects of combined emergency percutaneous cardiopulmonary support and reperfusion treatment in patients with refractory ventricular fibrillation complicating acute myocardial infarction. (2/79)

OBJECT: We conducted a prospective study to determine whether or not combined emergency percutaneous cardiopulmonary support (PCPS) and coronary reperfusion treatment are useful for acute myocardial infarction (MI) patients with unsynchronized electric shock-resistive ventricular fibrillation (VF). PATIENTS AND METHODS: Thirty-two acute MI patients who lapsed into the refractory VF were entered into the study. Group 1 consisted of 19 patients with VF outside the hospital, and Group 2 consisted of 13 patients with VF immediately after arrival at the hospital. The primary endpoint was successful reperfusion, return of spontaneous circulation and good recovery without neurologic disability. RESULTS: The infarct-related arteries showed a significant difference between Groups 1 and 2. However, the two groups had similar rates of successful reperfusion (84.6% vs 94.7%, respectively) and return of spontaneous circulation (89.5% vs 84.6%, respectively). The rates of good recovery were similarly low in both groups (5.3% vs 15.4%, respectively). CONCLUSION: Combined emergency PCPS and reperfusion treatment produced high return of spontaneous circulation, however the neurologic outcome was low.  (+info)

Right ventricular infarction with cardiogenic shock treated with percutaneous cardiopulmonary support: a case report. (3/79)

A patient with a right ventricular infarction was resuscitated with percutaneous cardiopulmonary support (PCPS), after attempts at reperfusion, high-dose inotropic support and intra-aortic balloon counterpulsation failed to improve the hemodynamic compromise. Emergency PCPS improved the cardiogenic shock and the reduced right ventricular load, allowing the ischemic right ventricle to recover in the setting of unsuccessful reperfusion. This case demonstrates the use of PCPS as a hemodynamic support device for spontaneous recovery of the ischemic right ventricle. PCPS may be a potential therapy for patients with right ventricular infarction.  (+info)

Acute severe cardiac failure complicating myocardial infarction. Experience with 100 patients referred for consideration of mechanical left ventricular assistance. (4/79)

One hundred patients were referred with suspected acute cardiac failure following acute myocardial infarction. The diagnosis was confirmed in 72: 31 of these patients underwent elective medical treatment, with 2 survivors (6%); 41 were accepted for counter pulsation, but 9 died before this could be initiated and another 2 died shortly after vain attempts to pass the balloon catheter were abandoned; 30 patients underwent counterpulsation with 14 hospital survivors (47%). Survivor status was usually good. Results of counter pulsation were better in patients who were not shocked (with 5/5 survivors) than in those who were in shock (with 9 of 25 survivors). Results support the view that counterpulsation (alone or combined with corrective surgery) may play an important role in the complications of myocardial infarction provided intervention is early.  (+info)

Long-term results of arterial counterpulsation in acute severe cardiac failure complicating myocardial infarction. (5/79)

Thirty patients were discharged from hospital after treatment with arterial counterpulsation for acute severe heart failure complicating myocardial infarction. Seventeen patients had been in cardiogenic shock--13 with power failure alone, and 4 with a mechanical complication which required corrective surgery. Thirteen patients were in impending or 'preshock'. The follow-up period after infarction averaged 13-1 months. Results were good in 'preshock' patients, and in shocked patients with a surgically correctable mechanical complication. Results were poor in shocked patients with power failure alone. Counterpulsation has an important supportive role in the treatment of complicated myocardial infarction, provided that intervention is prompt and mechanical complications, if present, are corrected early.  (+info)

Percutaneous cardiopulmonary support as a bridge to emergency operation--two surviving cases. (6/79)

Two patients had percutaneous cardiopulmonary support (PCPS) used as a bridge to emergency surgery. A 66-year-old man admitted with profound cardiogenic shock underwent direct stenting under PCPS with the diagnosis of acute myocardial infarction of the left main trunk, with the intention of performing revascularization as soon as possible. Subsequently, double coronary artery bypass grafting was successfully accomplished. A 69-year-old woman, admitted with acute heart failure due to critical aortic stenosis, manifested cardiogenic shock while undergoing catheterization. PCPS was immediately instituted until the acute deterioration of her hemodynamic state could be reversed, and was continued uneventfully till aortic valve replacement was performed. These results suggest that the current PCPS system is an effective response to acute circulatory collapse and will contributed to the improved survival of patients.  (+info)

Intra-aortic balloon counterpulsation: potential for therapy in hemorrhagic shock with associated myocardial failure. (7/79)

After attaching appropriate monitoring devices enabling the measurement of the slope of the left ventricular function curve, left atrial pressure, mean aortic pressure, peak left ventricular pressure, and tension time index, three groups of ten dogs were subjected to varying periods of hemorrhagic shock until a slope of their ventricular function curve was reduced to either 75% (Group I), 50% (Group II), or 25% (Group III) of their baseline value. Resuscitation was attempted in all dogs by the intravenous infusion of shed blood plus additional balanced salt solution. This infusate was administered to maintain either the mean aortic pressure within 15 mm Hg of the baseline value or a left atrial pressure of 15 mm Hg, whichever occurred forst. One half of the dogs received, in addition, intra-aortic balloon counterpulsation. All dogs not receiving counterpulsation expired within two hours. There was no apparent effect of counterpulsation on Group I animals. Three of five animals (Group II) and four of five animals (Group III) receiving counterpulsation survived to the end of the experiment with significant (p smaller than .01) improvement in the parameters monitored. The utilization of counterpulsation as an adjunct to treatment in hemorrhagic shock is suggested.  (+info)

Twenty-four hour left ventricular bypass with a centrifugal blood pump. (8/79)

A new centrifugal blood pump system has been developed for left ventricular bypass by the addition of non-thrombogenic blood surface materials and an ultrathin-walled cannula for the retrograde cannulation of the left ventricle. Partial LV bypass at 3 to 6 L/min was undertaken in 55 calves without thoracotomy. In 20 it was continued for 24 hours, with 13 survivors who were eventually sacrificed. Eleven of the last 14 experiments were completed without mishap. Heparin was employed only during pump insertion. Hematologic changes were limited to moderate platelet depression, and tolerable hemolysis (average serum level 21 mg% in the last 13 experiments). Normal clotting parameters and the absence of significant fibrin split product formation correlated with the absence of gross thrombosis and few minor renal emboli observed at autopsy. This pump system appears to have several advantages over previously described equipment for LV bypass.  (+info)

*Heat shock protein

Borges JC, Ramos CH (April 2005). "Protein folding assisted by chaperones". Protein and Peptide Letters. 12 (3): 257-61. doi: ... "Circulation Research. 83 (2): 117-32. doi:10.1161/01.res.83.2.117. PMID 9686751.. ... They play an important role in protein-protein interactions such as folding and assisting in the establishment of proper ... Circulation. 111 (14): 1792-9. doi:10.1161/01.CIR.0000160851.41872.C6. PMID 15809372.. ...

*Artificial heart

Prolonged Assisted circulation after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of ... A centrifugal artificial heart which alternately pumps the pulmonary circulation and the systemic circulation, causing a pulse ... Mechanical Devices to Assist the Failing Heart: Proceedings. National Academies. 1966.. *^ "Wayback Machine" (PDF). 2008-11-12 ... The first heart assist device was approved by the FDA in 1994, and two more received approval in 1998.[67] While the original ...

*Cardiopulmonary resuscitation

"Dispatcher-assisted cardiopulmonary resuscitation: risks for patients not in cardiac arrest". Circulation. 121 (1): 91-7. doi ... "Circulation. doi:10.1161/CIRCULATIONAHA.114.014542.. *^ a b Davis, Robert (July 28, 2003). "Special report: Many lives are lost ... "Circulation. 133 (4): e38-e360. doi:10.1161/CIR.0000000000000350.. *^ Go, Alan S.; Mozaffarian, Dariush; Roger, Véronique L.; ... "Circulation. 139 (10): e56-e528. doi:10.1161/CIR.0000000000000659.. *^ Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, ...

*Motility

It assists in the circulation of blood and protects and confines the visceral organs. It also provides the main shaping ...

*Euryclides de Jesus Zerbini

Assisted circulation with an auxiliary heart transplant. An experimental study. J Thorac Cardiovasc Surg. 1972 May;63(5):696- ... Circulation. 1996 Oct 15;94(8):1815-7. PMID 8873654 Zerbini EJ. Results of replacement of cardiac valves by homologous dura ...

*Rover 14

Water circulation was assisted by an impeller. By the time of the following Motor Show the worm drive at the rear of the engine ...

*Artificial heart

Prolonged Assisted circulation after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of ... A centrifugal artificial heart which alternately pumps the pulmonary circulation and the systemic circulation, causing a pulse ... The first heart assist device was approved by the FDA in 1994, and two more received approval in 1998. While the original ... An artificial heart is distinct from a ventricular assist device (VAD) designed to support a failing heart. It is also distinct ...

*Artificial heart

Prolonged Assisted circulation after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of ... A centrifugal artificial heart which alternately pumps the pulmonary circulation and the systemic circulation, causing a pulse ... Mechanical Devices to Assist the Failing Heart: Proceedings. National Academies. 1966.. *^ "Wayback Machine" (PDF). 12 November ... The first heart assist device was approved by the FDA in 1994, and two more received approval in 1998.[78] While the original ...

*Pia mater

CSF production and circulation[edit]. Cerebrospinal fluid is circulated through the ventricles, cisterns, and subarachnoid ... There it is called the central ligament and assists with movements of the trunk of the body.[6] ... The pia spans every surface crevice of the brain other than the foramina to allow the circulation of CSF to continue.[9] ... About 150 mL of CSF is always in circulation, constantly being recycled through the daily production of nearly 500 mL of fluid ...

*West Burton power stations

The four boilers have single divided furnaces and assisted circulation. Each has a maximum continuous rating of 1565 t/h ( ... The Executive partner for (ADG) was Rex Savidge and Architect in charge was John Gelsthorpe assisted by Norman Simpson. West ...

*Domingo Liotta

1962 (May): Prolonged assisted circulation during and after cardiac and aortic surgery. Prolonged partial left ventricular ... Assisted Circulation for Chronic Heart Failure, International Society for Artificial Organs (ISAO), U.S. 2005: Decoration, ... 1961(December): First conception of the prolonged mechanical assist circulation in the treatment of Cardiogenic Shock ... Dr Liotta is still actively working in research and development of new models of heart assist devices, and spending time with ...

*Alexander Fraser Pirie

As a young man, Alexander Fraser Pirie assisted at his father's newspaper office. The paper struggled to maintain circulation ... The children's guardian was their paternal aunt, Ada L. Murdoch, who had been assisting Pirie since the death of her sister-in- ... Jane Pirie had actively assisted in her husband's publishing and printing business in Guelph, and in the 1890s had drafted an ...

*William S. Pierce

Richenbacher WE and Pierce WS: Chapter 19: Assisted Circulation and the Mechanical Heart. In, Heart Disease. Fifth Edition. Ed ... The Pierce-Donachy Ventricular Assist Device, also known as the Penn State Assist Pump, was designated an International ... The original pneumatic heart assist pump, now known as the Thoratec ventricular assist device (Thoratec Pneumatic VAD), has ... His pioneering work led him to be considered around the world as a father of the ventricular assist device. The group, ...

*Thomas Fowler (inventor)

By the 1960s, the space heating circulation system was assisted by an electric pump. Switching from coal heating to gas boilers ... In large houses these would be placed in a basement, allowing thermosiphon circulation throughout the house. Nearly a century ... The height difference between boiler and storage allowed thermosiphon circulation in this simple large bore primary circuit. ... also drove a switch to reliable pumped circulation in the 1970s. With the disappearance of stored hot water in favour of the ...

*Strongylida

The third-stage larvae are carried by general circulation to the heart and lungs. In the lungs, they enter alveoli and begin to ... The larvae release enzymes to assist their passage through the skin. There are three species that infect humans. Fourth-stage ...

*Paul Martin (illustrator)

Referee Paul assisted her off the court. The Post-Star, July 21, 1925 p. 11. "Younger Tennis Players". The Scarsdale Inquirer, ... The main culprit was television, which dramatically took away from its advertising and circulation revenue. Collier's top ... His wife assisted in preparing the models for their scenes. Collier's couldn't keep up with the rapidly changing times ...

*Turndown ratio

In practice only boilers with fan assisted fuel/air circulation will have the modulating feature. The fan also mixes gas and ...

*Library

From 1978 to 2004, book circulation per user declined approximately 50%. The growth of audiovisuals circulation, estimated at ... a process that may be assisted through signage, maps, GPS systems, or RFID tagging. ... Circulation (or Access Services) - Handles user accounts and the loaning/returning and shelving of materials.[137] ... Morris, V. & Bullard, J. (2009). Circulation Services. In Encyclopedia of Library and Information Sciences (3rd ed.). ...

*Chemist + Druggist

It is audited by the Audit Bureau of Circulations and has a circulation of 13,675. Chemist + Druggist features the latest UK ... community pharmacy news on business and clinical issues; articles and training courses to assist pharmacists with their ...

*Weekly newspaper

This larger circulation can assist in bringing in national advertising to weeklies. Weeklies in chains may also have a ... A circulation manager keeps track of subscribers (this can range from only a couple hundred to tens of thousands of subscribers ... The size of the news staff varies, depending on the size of the newspaper and its circulation area. Some papers have a staff of ... Such newspapers tend to have smaller circulations than daily newspapers, and are usually based in less-populous communities or ...

*Beckley Foundation

LSD, psilocybin, and MDMA-assisted psychotherapy for conditions such as depression,[18] anxiety, addiction, and post-traumatic ... cerebral circulation, cranial compliance, and their relationship to age-related cognitive decline. ... psychedelic-assisted therapy. Amanda Feilding and the Beckley Foundation are currently trying to secure funding to expand this ... "Implications for psychedelic-assisted psychotherapy: Functional magnetic resonance imaging study with psilocybin". British ...

*Typhoon Ida (1958)

About 200 firemen along the Kano River assisted in relief efforts. Tropical cyclones portal Other storms of the same name ... Emanuel M. Ballenzweig (1958). "The Weather and Circulation of September 1958" (PDF). Monthly Weather Review. 86: 359-367. ... After the storm subsided, the United States military provided supplies and soldiers to assist in relief work. ...

*Foramen secundum

Circulation. 9 September 2003; 108 Suppl 1:II191-4. Bolz D, Lacina T, Buser P, et al. Long-term outcome after surgical closure ... Five-year Follow-up of Intracardiac Echocardiography-assisted Transcatheter Closure of Complex Ostium Secundum Atrial Septal ... Circulation. 1 October 2002; 106(14):1821-6. Groundstroem, et al. Late postoperative follow-up of ostium secundum defect. ...

*James McCudden

Only the high-altitude bombers were equipped with oxygen equipment to assist with breathing. Despite his circulation ... Operating the D.H.2 in 1916, he suffered terrible agonies as adequate blood circulation returned to his muscles once he reached ...

*Limpet

The odontophore may play a large role in assisting with blood circulation as well. The two kidneys are very different in size ...

*S100A1

... lack of recovery following left ventricular assist device support". Circulation: Heart Failure. 7 (4): 612-8. doi:10.1161/ ... Reduced expression of this protein has been implicated in cardiomyopathies, and left ventricular assist device-based therapy ... Circulation. 114 (12): 1258-68. doi:10.1161/CIRCULATIONAHA.106.622415. PMID 16952982. Pleger ST, Most P, Boucher M, Soltys S, ... Circulation. 115 (19): 2506-15. doi:10.1161/CIRCULATIONAHA.106.671701. PMID 17470693. Descamps, B; Madeddu, P; Emanueli, C (4 ...

*Positron emission tomography

These amyloid imaging probes permit the visualization of amyloid plaques in the brains of Alzheimer's patients and could assist ... 2002). "Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography". Circulation. ... Journal of Computer Assisted Tomography. 3 (6): 804-814. doi:10.1097/00004728-197903060-00018. ISSN 0363-8715. PMID 315970.. ... usually into blood circulation). Each tracer atom has been chemically incorporated into a biologically active molecule. There ...

*American Library (New Delhi)

Its collection of DVDs includes movies, data, and software which is available for circulation. The library offers an online ... catalog database to assist patrons in locating library materials. The American Library plans commemorative events on the topics ... The American library in New Delhi has 14 staff members running the circulation desk and reference sections and another 10 ...
METHODS AND RESULTS Eighteen dogs were instrumented with regional myocardial function sonomicrometers in the ischemic and control zones. The left anterior descending coronary artery just distal to the first diagonal branch was instrumented with a silk snare and Doppler flow probe. Additionally, pressure catheters were placed in the left atrial appendage, left ventricular apex, and ascending aorta for hemodynamic measurements. Regional myocardial blood flow was determined by using 15-microns radioactive microspheres. Measurements were made in the control state, immediately after coronary occlusion, at 1 and 2 hours after coronary occlusion, with reperfusion, and 1 hour after reperfusion. In treated animals, left ventricular assistance was maintained during the entire period of occlusion and reperfusion. The Hemopump was associated with a significant decrease in left ventricular systolic and diastolic pressure, whereas mean arterial pressure was maintained. Intra-aortic balloon counterpulsation ...
TY - JOUR. T1 - Prolonged mechanical support of the left ventricle.. AU - Pierce, W. S.. AU - Donachy, J. H.. AU - Landis, D. L.. AU - Brighton, J. A.. AU - Rosenberg, Gerson. AU - Migliore, J. J.. AU - Prophet, G. A.. AU - White, W. J.. AU - Waldhausen, J. A.. PY - 1978/1/1. Y1 - 1978/1/1. N2 - An interdisciplinary group has developed a left ventricular assist pump system composed of a modified sac type pump, a pneumatic power unit, and a synchronizer. The pump fills from the left ventricle and discharges into the aorta. The system was employed for left ventricular assistance in a series of 12 normal calves, with an average pumping period of 70 +/- 8 days. The system was then evaluated in a series of calves in whom profound left ventricular failure had been produced. These studies indicate that the assist pump is effective in supporting the circulation and completely unloading the left ventricle. The assist system has now been employed in four patients who could not be weaned from ...
Prof. Stephan Schueler is a past president of ISHLT and of the ESCVS. He helped to set up both the Berlin Heart Centre, and a new centre in Dresden before moving to the Freeman Hospital, where he leads the Ventricular Assist Device Programme, which is the subject of this interview. Also shown are his implantation technique and an interview with one of his patients ...
An institutional registry of ECMO patients was surveyed to determine predictors of survival among patients receiving ECMO in the presence of sepsis. Among 151 studied patients, pneumonia was the most common cause of sepsis. Mortality was predicted by advanced age, longer door-to ECMO times, gram-negative sepsis, and sepsis due to infections other ...
A device to be inserted in a blood vessel in order to aid the pumping of blood in only one direction within that vessel which comprises a gas inflatable and deflatable chamber mounted on support means and divided into an occluding section and a pumping section in direct communication with each other, such that it is necessary to deliver gas directly only to the occluding section, thereby enabling the occluding and pumping sections to be mounted on the support means in any order which further enables the device to be inserted from either above or below the vessel and which also permits thinner and therefore more easily insertable support means when the sections are mounted for insertion from below.
CHD and non-CHD patients had similar levels of clinical support required at transplantation. Within the reoperation group, CHD patients were much less likely to have mechanical circulatory assistance at transplantation, likely representing both underutilization of and fewer appropriate candidates for MCS.. In the population examined by Patel et al, 21 CHD patients were more likely to have a higher PVR (,4 Wood units); in this more contemporary population, we did not find a similar difference. We also did not find a statistically significant impact of elevated PVR on posttransplantation outcomes. PVR is a problematic variable in CHD transplantation patients, many of whom have single-ventricle physiology.20 Neither the United Network for Organ Sharing database nor most single-institution studies18,22 have information about the catheter locations used to measure pretransplantation and posttransplantation pulmonary pressures or about the presence of aortopulmonary collaterals. Further work is needed ...
If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patients written consent to publication and send them to the editorial office before submitting your response [Patient consent forms] ...
The story takes place in the same official Code Geass history as the anime, but in a different era. The title character, Renya, is a 17-year-old boy with a mechanical left arm and shuriken throwing stars as his weapons of choice. The story begins when Renya encounters a mysterious, perpetually young witch named "Reifū C.C." C.C. has appeared in Japans historical Edo era to seek a new partner for a covenant. Meanwhile, a mysterious man, with a striking resemblance to the character Lelouch of the original anime, also appears with unknown intentions ...
NEW YORK - Surgeons at NewYork-Presbyterian Hospital/Columbia University Medical Center performed the first Total Artificial Heart implant in the New York City area to replace a patients dying heart.. "For patients who will die without a heart transplant, the Total Artificial Heart helps them survive until they can get one. By replacing the heart, we are eliminating the symptoms and the source of heart failure," said lead surgeon Dr. Yoshifumi Naka, director of Cardiac Transplantation and Mechanical Circulatory Support Programs at NewYork-Presbyterian/Columbia and associate professor of surgery at Columbia University College of Physicians and Surgeons.. Similar to a heart transplant, the SynCardia temporary Total Artificial Heart replaces both failing heart ventricles and all four heart valves. Once implanted, the Total Artificial Heart provides immediate blood flow of up to 9.5 liters per minute. This high volume of blood flow helps speed the recovery of vital organs, including the brain, ...
An inventor from Turkey presented at the International Exhibition of Inventions of Geneva 2014 the invention: "Permanent" Total Artificial Heart".. This invention is about "permanent" total heart device which has been developed for patients who have end-stage heart failure and who are considered for heart transplantation. Via a surgical operation, the device is placed whether completely inside the ventricles of the patients heart or it is placed to the convenient space obtained through removing part of the ventricles. The specially designed motor requires quite a little energy and works simultaneously with ECG signals assuring pulsatile blood flow.. It is often difficult to find suitable heart donors for patients with en-stage heart failure. Therefore, the development of total artificial heart devices is often the only choice. With the development of these devices, it seems that the heart transplantation will not be needed and instead bionic hearts will be used.. The invented artificial heart ...
TUCSON, Ariz., Oct. 4, 2012/ PRNewswire/-- SynCardia Systems, Inc., manufacturer of the worlds first and only FDA, Health Canada and CE approved Total Artificial Heart, announced today that University Medical Center Ljubljana has transplanted Slovenia s first patient to receive the SynCardia temporary Total Artificial Heart.
What Are VADs? Left Ventricular Assist Devices, or known more commonly as LVADs or simply VADs, are designed to take over the function of the weakened hearts left ventricle, which delivers oxygenated blood from the heart to the body. The device, which is implanted in the patients chest, consists of an electric motor and a driveline. A tube placed in the left ventricle diverts blood from the heart to the VAD pump. The pump then propels the blood back into the aorta and out to the rest of the body. This is also known as mechanical circulatory support.
The significance of the utilization of mechanical circulatory support following a myocardial infarction is not well defined. We present a systematic review of this treatment alternative and suggest guidelines to be considered in the treatment of thes
BACKGROUND: Historically, the "temporary" or short-term ventricular assist device (VAD) was used only as a quick bridge to recovery for children with an acute process. In the current era, the devices that were originally used for temporary support are now being used to support children for longer durations and for a variety of indications. In this study we aimed to describe the overall use, patients characteristics and outcomes of "temporary" VAD use in children. METHODS: The Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS) is a National Institutes of Health-supported national registry for United States Food and Drug Administration-approved VADs in patients ,19 years of age at the time of VAD implantation (either durable or temporary VAD ...
The 10th International Conference on Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion will be held at the Hall of Flags, University of Pennsylvania, Philadelphia, PA, USA, May 28-31, 2014. Preliminary scientific program is attached for your review.. All abstracts must be submitted online via the conference web site. http://pennstatehershey.org/web/pedscpb/home Please use the same link for conference registration, hotel room and exhibitor registration.. The scientific program of the 10th event has special additional features such as Pediatric CPB-ECLS-MCS Wet-labs, Simulations, Hospital Tours & Case presentations for all pre-registered participants. Important Dates (2013-2014). DATE EVENTS. December 16, 2013 Conference & Hotel Registration Begins. December 16, 2013 Abstract Submission Begins ? Online Only. March 1, 2014 Exhibitor Booth Registration Deadline. March 1, 2014 Final Day for Abstract Submissions. March 7, 2014 Notification of Accepted ...
Mechanical Circulatory Support Therapy In Advanced Heart Failure von Deng Mario C & Naka Yoshifumi und Buchbewertungen gibt es auf ReadRate.com. Bücher können hier direkt online erworben werden.
Purpose of Review To outline key elements in providing compassionate end-of-life care for pediatric patients with end-stage heart failure on mechanical circulatory support (MCS) such as extracorporeal...
Health, ...BOSTON MA April 9 2008 New devices and research for mechanical cir...The use of mechanical circulatory support devices (MCSDs) is shown to ...Acknowledging this vacancy the NHLBI Pediatric Circulatory Support Pr...The field of pediatric mechanical circulatory support received a boost...,New,research,for,mechanical,support,devices,in,pediatrics,to,be,released,at,ISHLT,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
[134 Pages Report] Check for Discount on Global Intra-aortic Balloon Pump (IABP) Market Status and Future Forecast 2015-2025 report by 99Strategy. Summary The Intra-aortic balloon pump (IABP) is a mechanical...
An intra-aortic balloon pump includes a balloon, a catheter having a relatively small diameter lumen and an extender having a relatively large diameter lumen connected in series. A valve is positioned in the extender adjacent the end of the extender connected to the catheter. The valve enables the extender to be pressurized with a working gas prior to inflation of the balloon and to be evacuated prior to deflation of the balloon. A second valve adjacent the opposite end of the extender permits the intra-aortic balloon pump to commence a pre-inflation step or a pre-deflation step without affecting the pressure in the extender. Separate positive pressure and negative pressure extenders may be provided to reduce the movement of the working gas during inflation and deflation cycles, thereby increasing pneumatic efficiency.
Professor of Surgery (212) 305-0828 Yoshifumi Naka, MD, PhD, is an internationally known heart transplant surgeon and a pioneer in mechanical assist therapy for heart failure. Under his leadership, Columbia University Medical Centers Cardiac Transplantation and Mechanical Circulatory Support Programs have earned international recognition for their contributions in developing and testing new cardiac devices and in training cardiothoracic surgeons around the world. Columbias heart transplant program is the largest U.S. heart transplant program by volume. Dr. Nakas clinical specialties include adult cardiac surgery for coronary artery disease, valvular heart disease, heart transplantation, and mechanical circulatory support device implantation. His research has focused on cardiac and pulmonary transplantation, organ preservation, surgical treatment of atrial fibrillation, vein graft disease after bypass surgery, and outcomes of clinical mechanical circulatory support device surgery and heart
One of several devices proposed to provide circulatory assistance to victims of cardiogenic shock is the intra-aortic balloon pumping technique which utilizes a polyurethane balloon that is inserted through a femoral artery and advanced to a predetermined position in the descending aorta. The balloon is pneumatically driven and typically controlled so as to raise systemic pressure immediately after left ventricular ejection and aortic valve closure. The pressure remains elevated throughout diastole and is lowered via balloon deflation prior to the succeeding ventricular ejection. This form of ventricular assist device has as its goals (1) reduction of the work required of the failing myocardium via reduction of pressure load on the left ventricle and (2) partial replacement of the circulatory role played by the heart by increased mean central aortic pressure and effective cardiac output. As a result, blood flow to the coronary and cerebral circulations is enhanced and increased oxygen supply to ...
TUCSON, Ariz., July 31, 2014 (GLOBE NEWSWIRE) -- For the first time, cardiac surgeons, medical professionals and the public can watch the implantation of the SynCardia temporary Total Artificial Heart in a peer reviewed case report paper and matching video posted on the Journal of Visualized Experiments website.
A growing number of people with failing hearts are being given total artificial hearts as they wait for donor hearts to become available. To implant…
Cardiovascular disease is the major cause of mortality and morbidity in the industrialized world. Although death rates from coronary heart disease have been declining, heart failure, which is usually the consequence of obstruction of the coronary arteries, is on the increase. Heart failure is a progressive, debilitating condition that accounts for a high proportion of hospital admissions and readmissions. For some years the only surgical option for treating heart failure has been cardiac transplantation. Unfortunately fewer donor hearts are becoming available, and the number of transplantation operations performed has therefore been falling year by year, despite rising demand. Many patients cannot meet the strict age and other criteria for transplant surgery. Of those who are placed on the waiting list, 25-30% die before a suitable donor is found. Even for those who receive the operation, transplantation may not be a perfect solution. Transplanted hearts often fail through rejection or ...
Worlds Smallest Artificial Heart The worlds smallest artificial heart, made by Italian scientists. This tiny titanium pump was implanted in a baby, at the Bambino Gesu Hospital in Rome May 24, 2012. Doctors from Romes Bambino Gesu Hospital saved the life of the 16-month-old baby with this Artificial heart.
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership.. Click Here to Learn More ...
The intra-aortic balloon pump, or simply IABP, is a catheterization procedure involving a balloon. The device is inserted into the aorta and is used to increase blood flow to the heart and reduce cardiac output. Although the procedure is sometimes elective, this may not be the case when it comes to a cardiac emergency. The IABP is most often used in individuals suffering from acute heart attack, heart failure and during certain kinds of heart surgery. Risks of having the balloon pump include, but are not limited to, infection, embolism and blockage of other arteries.
Persistence Market Research in its latest study on the global intra-aortic balloon pump market finds that factors such as high risk of infection and potential dangers of artery
An inflow conduit assembly for conducting blood from a ventricle to a Ventricular Assistance Device (VAD) is provided. The assembly includes a rigid tube including an angled heart engaging end for insertion into a ventricle. The angled heart engaging end defines a long side for placement adjacent a heart septum. The tube includes an orifice end for attachment to the VAD, and the inflow conduit assembly further includes a coupling for attaching the orifice end of the tube to the VAD. The coupling is movable between a rotatable position wherein the tube is rotatable relative to the VAD, and a locked position wherein the tube is immobile relative to the VAD.
This artificial heart you see here grosses me out, but count me in if it will be able to save lives. Originally invented by a human who is now too feeble to even row a boat, the artificial heart can pride itself in being the first practical robot organ to be incorporated into a living Russian dog. Unfortunately for us humans, our body will most likely reject plastic organs since we arent Barbies to begin with. Thankfully the advances of science has since been able to make us survive much longer than we ought to, and I would love to see more technologically advanced medical discoveries in the near future, with the artificial heart paving the way.. Source: Boing Boing Gadgets. ...
The concept of mechanical circulatory devices to support functional survival has been validated during the past 40 years of development and is further supported by the INTrEPID trial (3). Before the conclusion of this trial, it became clear from other experience that devices can no longer be tested in this dying population in a simple randomized trial design. However, the major questions remain simple: How long and how well do the patients live?. The answer to how long is currently expressed not by relative reductions of mortality, but in absolute survival with a given device. When survival without devices is negligible, the main component of the equation of net benefit is the survival with devices. A case could be made, particularly with hindsight, that the INTrEPID trial did not need a control group, because the major issue was outcome with the device, not outcome without it. Had 75% of patients survived 1 year, the trial would have been positive. Had 50% of patients survived 1 year, the ...
TY - JOUR. T1 - Fulminant Myocarditis. T2 - Epidemiology, Pathogenesis, Diagnosis, and Management. AU - Sharma, Ajay Nair. AU - Stultz, Jacob Randolph. AU - Bellamkonda, Nikhil. AU - Amsterdam, Ezra Abraham. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Fulminant myocarditis (FM) is a rare, distinct form of myocarditis that has been difficult to classify. Since 1991, the definition of FM has evolved, and it is currently considered an acute illness with hemodynamic derangement and arrhythmias due to a severe inflammatory process requiring support of cardiac pump function and/or urgent management of serious arrhythmias. Diagnosis is aided through use of biomarkers and cardiac imaging, but endocardial biopsy remains the gold standard. Recent evidence has revealed that patients with FM are significantly more likely to die or require heart transplantation than those with the nonfulminant form, refuting previous studies proposing a paradoxically low mortality in patients with FM. Acute hemodynamic derangement is ...
Intra-aortic balloon apparatus is disclosed including a single chamber balloon sealably attached to the end of a catheter for non-surgical insertion into the aorta through the skin as by the standard Seldinger technique. In the preferred embodiment, the extreme end of the balloon is fixedly attached to one end of a separate substantially circumferentially rigid but longitudinally flexible tube open at both ends and disposed within and extending the length of the catheter. The opposite end of the tube remote from the balloon is fixedly attached to means for effecting rotation of the tube within the catheter and thereby result in controlled sequential wrapping and unwrapping of the balloon about the tube. In use, the balloon is pumped in conventional manner via the catheter and access through the tube is provided to the interior of the aorta at the extreme end of the balloon. When the end portion of the tube within the balloon is formed of a relatively flacid or flexible material, it is advantageous to
Tucson, Ariz. (PRWEB) October 08, 2013 -- Kevin Stroh, 25, was fighting for his life against congestive heart failure, the same disease that claimed the life
The Jarvik 2000 heart includes the blood pump inside the natural heart (white arrow), the internal cable (blue arrow), the behind-the-ear connector (green arrow) the belt worn controller (yellow arrow), the belt worn battery (grey arrow), and the external cables (black).. Here we cover the background, basic design elements, and surgical placement of the patented Jarvik 2000 post-auricular cable and connector. Transmission of power into the body has been one of the most difficult problems for developers of mechanical circulatory support devices.. The performance objectives are well defined and include:. ...
A 40-year-old woman became the world`s first female artificial heart patient Thursday, receiving a smaller version of the Jarvik-7 pump designed for her chest cavity, hospital officials said.Mary
France has begun the first human trial of artificial heart, which aims at overcoming shortages of organs available for transplant.
The second person in France to receive a much-hyped new-generation artificial heart has died eight months after receiving the transplant, biomedical firm Carmat said Tuesday.
The smallest artificial heart in the world, weighing only 11 grams, was enough to save life of an infant boy suffering a deadly disease. Italian doctors who completed the surgery say it kept the baby alive till a donor was found.
Artificial heart technology has been around a while, but this new invention by European scientists is so convincing in its emulation of a real hearts...
Artificial heart patient Anthony Mandia yesterday continued to rebound from Tuesdays setback, when he lapsed in and out of a near-unconscious state for several hours.Dr. John Burnside, spokesman
Its been a bad week for the medgadget industry, beginning with the Guidant defibrillator recall, and now the FDA rejection of AbioMeds artificial heart,
The Centers for Medicare & Medicaid Services (CMS) has proposedcoverage with evidence development of artificial heart devices forMedicare beneficiaries who are enrolled in FDA-approved studies.
Pavan Atluri, MD | Director, Cardiac Transplantation and Mechanical Circulatory Support Program | Cardiac Surgery, Cardiac Surgery | Penn Medicine
SynCardia - Manufactures the SynCardia temporary Total Artificial Heart for patients with end-stage, biventricular heart failure in need of a donor heart transplant
Answering the demand for acomprehensive, all-purpose volume focusing on the challenging needs of pediatric patients, Mechanical Support for Cardiac and
It was just like any other daily run for Andrew Jones. He put one foot in front of the other. He breathed in. He breathed out. He made it to the mailbox, but he knew something wasnt right.It kind of felt like my lungs had turned into sponges. Like I was breathing through a sponge.That bizarre fee...
Jim Lynskey is the youngest person in the UK living with an LVAD. Read about his experience and watch a video of Jim talking about his daily life.
The TandemLife platform is a comprehensive circulatory support system that will enable you to initiate ECLS procedures with confidence.
We are very pleased to bring this important new treatment to Iowa," said James Davis, M.D., the cardiothoracic surgeon who implanted the device. "This technology can help patients, who previously did not have any good options, to survive until a donor heart becomes available.". The SynCardia temporary Total Artificial Heart is the worlds first and only FDA, Health Canada and CE (Europe) approved Total Artificial Heart. It is currently approved as a bridge to transplant for people dying from end-stage heart failure affecting both ventricles (biventricular failure). There have been more than 900 implants of the Total Artificial Heart, accounting for more than 210 patient years of life.. Similar to a heart transplant, the Total Artificial Heart replaces both failing heart ventricles and the four heart valves, eliminating the symptoms and source of end-stage biventricular failure.. "Before this treatment became available, patients who received this kind of cardiac support had to stay in the ...
SynCardia Systems, Inc. (www.syncardia.com), manufacturer of the worlds first and only FDA, Health Canada and CE (Europe) approved Total Artificial Heart, announced today record-setting results for 2012 for implants, revenue and profit.. (Photo: http://photos.prnewswire.com/prnh/20130117/LA44048) "2012 was a momentous year for the SynCardia temporary Total Artificial Heart with a record-breaking 125 implants performed at more than 50 Certified Centers worldwide," said Michael Garippa, SynCardia Chairman/CEO/President. "We expect our growth trajectory to continue in 2013 as we pursue a Humanitarian Device Exemption (HDE) from the FDA for destination therapy and plan to introduce our smaller 50cc Total Artificial Heart designed to fit patients with a body surface area of less than 1.7." SynCardias accomplishments in 2012 include: -- Completion of required patient enrollment in the FDA clinical study of the [email protected] portable driver, the worlds first wearable power supply for the SynCardia Total ...
CRISP AMI: Intra-aortic Balloon Counterpulsation and Infarct Size in Patients with Acute Interior Myocardial Infarction Without Shock. -Trial Overview by Dr. Magnus Ohman and Dr. Manesh Patel (ESC 2011). IABP-SHOCK II: Randomized comparison of intra-aortic balloon counterpulsation versus optimal medical therapy in addition to early revascularization in acute myocardial infarction complicated by cardiogenic shock. -Trial Overview by Dr. Holger Thiele (ESC 2012). PROTECT II: Prospective Multicenter Randomized Trial Comparing IMPELLA to IABP in High Risk PCI. -90-Day Results by Dr. John Lasala (C3 Complex Intervention Meeting 2011) ...
Intra-aortic balloon counterpulsation therapy has been the first-line strategy for patients requiring mechanical circulatory support for more than 40 years. No other percutaneous support device has proven superiority over IABPs for treating patients with acute coronary syndrome and other complications of heart failure.
article{28149d91-751a-461c-b89d-25e9af4e3aae, author = {Ciarka, Agnieszka and Edwards, Leah and Nilsson, Johan and Stehlik, Josef and Lund, Lars H}, issn = {0167-5273}, language = {eng}, pages = {225--227}, publisher = {Elsevier}, series = {International Journal of Cardiology}, title = {Trends in the use of mechanical circulatory support as a bridge to heart transplantation across different age groups}, url = {http://dx.doi.org/10.1016/j.ijcard.2016.10.049}, volume = {231}, year = {2017 ...
Looking for online definition of artificial heart in the Medical Dictionary? artificial heart explanation free. What is artificial heart? Meaning of artificial heart medical term. What does artificial heart mean?
Artificial heart valves Suppliers, Artificial heart valves Manufacturers, Artificial heart valves Exporters and Artificial heart valves Business Leads from the technical textile industry worldwide - TechnicalTextile.net
TY - JOUR. T1 - The role of the total artificial heart in the treatment of post-myocardial infarction ventricular septal defect. AU - Ashfaq, Awais. AU - Jaroszewski, Dawn E.. AU - Pajaro, Octavio E.. AU - Arabia, Francisco A.. PY - 2013/2. Y1 - 2013/2. UR - http://www.scopus.com/inward/record.url?scp=84872312264&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84872312264&partnerID=8YFLogxK. U2 - 10.1016/j.jtcvs.2012.11.018. DO - 10.1016/j.jtcvs.2012.11.018. M3 - Article. C2 - 23219500. AN - SCOPUS:84872312264. VL - 145. JO - Journal of Thoracic and Cardiovascular Surgery. JF - Journal of Thoracic and Cardiovascular Surgery. SN - 0022-5223. IS - 2. ER - ...
Also known as: Heart Assist Pump, Heart Pump, and Mechanical Circulatory Support System). Over the last several decades, doctors and researchers have developed a new generation of devices to mechanically assist blood circulation. Some of these devices replace the function of the left ventricle, which is weakened in heart failure patients. Others supplement it rather than replace it. Assist devices are therefore markedly different from their total artificial heart predecessors.. The Jarvik 2000® Ventricular Assist Device is sometimes called a "booster" pump. Implanted inside the intact biological heart, it aids the left ventricle in ejecting blood. The flow produced by the Jarvik 2000 is synchronized with the heartbeat so that the blood moves in natural pulses. Most heart failure patients retain enough heart function to make this kind of support more reliable and effective - not to mention more comfortable - than that of a total artificial heart or device that produces the total output of a ...
TY - JOUR UR - http://lib.ugent.be/catalog/pug01:7037711 ID - pug01:7037711 LA - eng TI - Is there a place for intra-aortic balloon counterpulsation support in acute right ventricular failure by pressure-overload? PY - 2015 JO - (2015) INTERNATIONAL JOURNAL OF CARDIOLOGY SN - 0167-5273 PB - 2015 AU - Vanden Eynden, Frédéric GE10 000120959808 AU - Mets, Gilles AU - De Somer, Filip GE10 801002082325 0000-0001-7113-4565 AU - Bouchez, Stefaan 002005599884 AU - Bové, Thierry GE10 000080791094 ER ...
Intra-aortic balloon pumps (IABPs) continue to be the most widely used cardiac support devices with an annual estimate of 200 000 IABPs placed worldwide. IABPs enhance myocardial function by maximizing oxygen supply and minimizing oxygen demand. The
6.3 Japan Intra-aortic Balloon Pump (IABP) Sales Volume and Market Share by Type. About - Acute Market Reports :. Acute Market Reports is the most sufficient collection of market intelligence services online. It is your only source that can fulfill all your market research requirements.We provide online reports from over 100 best publishers and upgrade our collection regularly to offer you direct online access to the worlds most comprehensive and recent database with expert perceptions on worldwide industries, products, establishments and trends.. Our team consists of highly motivated market research professionals and they are accountable for creating the groundbreaking technology that we utilize in our search engine operations to easily recognize the most current market research reports online.. Website : http://www.acutemarketreports.com. Browse All Reports of This Category - http://www.acutemarketreports.com/category/medical-equipments-market. Our Blog :- ...
Get information, facts, and pictures about artificial heart at Encyclopedia.com. Make research projects and school reports about artificial heart easy with credible articles from our FREE, online encyclopedia and dictionary.
TY - JOUR. T1 - An implantable centrifugal blood pump for long term circulatory support. AU - Yamazaki, Kenji. AU - Litwak, Philip. AU - Kormos, Robert L.. AU - Mori, Toshio. AU - Tagusari, Osamu. AU - Antaki, James F.. AU - Kameneva, Marina. AU - Watach, Mary. AU - Gordon, Lisa. AU - Umezu, Mitsuo. AU - Tomioka, Jun. AU - Koyanagi, Hitoshi. AU - Griffith, Bartley P.. PY - 1997/9. Y1 - 1997/9. N2 - A compact centrifugal blood pump was developed as an implantable left ventricular assist system. The impeller diameter is 40 mm and the pump dimensions are 55 X 64 mm. This first prototype was fabricated from titanium alloy, resulting in a pump weight of 400 g including a brushless DC motor. Weight of the second prototype pump was reduced to 200 g. The entire blood contacting surface is coated with diamond like carbon to improve blood compatibility. Flow rates of over 7 L/min against 100 mmHg pressure at 2,500 rpm with 9 W total power consumption have been measured. A newly designed mechanical seal ...
Little information has been published on quality of life of children supported with mechanical circulatory support (MCS) (ECMO or VAD) with end stage heart failure. This paper examined the quality of life (QoL) scores, 3 years post transplant, in 84 children with cardiomyopathy. Of these children, 26 were bridged to transplant with mechanical circulatory support. Their study found that despite a greater severity of illness in those requiring MCS, there was no difference in quality of life measures when compared to those who did not require MCS at 3 years post transplant. This study did however identify that younger age of transplantation was associated with decrease QoL scores. This study highlights the lack of long term effects of MCS on QoL but also brings into question what the role MCS has on QoL while waiting for transplant or in the early period post transplant. ...
April 2, 2009 - Vasomedical Inc. this week conducted two presentations on the beneficial effects of EECP external counterpulsation therapy at the 58th Annual Scientific Session of the American College of Cardiology (ACC) in Orlando.. The external EECP counterpulsation therapy is a noninvasive, outpatient therapy used in the treatment of ischemic cardiovascular diseases, currently used to manage chronic stable angina and heart failure. The therapy increases blood flow and oxygen supply to the heart muscle and other organs and decreases the hearts workload and need for oxygen. Function of the endothelium, the inner lining of blood vessels throughout the body, is also improved, lessening resistance to blood flow. These actions reduce or eliminate symptoms of angina and heart failure, the company said. The first presentation by Randy W. Braith, M.D., Richard C. Conti, M.D., and colleagues from the University of Florida in Gainesville demonstrated that EECP therapy significantly improves brachial ...
Cardiology Research and Practice is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies that focus on the diagnosis and treatment of cardiovascular disease. The journal welcomes submissions related to systemic hypertension, arrhythmia, congestive heart failure, valvular heart disease, vascular disease, congenital heart disease, and cardiomyopathy.
The American Society of ExtraCorporeal Technology was founded in 1964 with the belief that members of the then-new allied health field could best serve their profession by sharing their thoughts and experiences. Steady growth was the keynote of AmSECT, as the ranks of Perfusionists expanded with the increasing demand for open-heart surgery. During the past decade, changes in lifestyle and improvements in the treatment of cardiac disease have resulted in Perfusionists facing the challenge of identifying new opportunities and expanded their practices in the areas of perioperative blood management, wound healing, ventricular assistance, and expanded uses of extracorporeal circulation.. Today AmSECT has over 2,000 members throughout the world and is dedicated to promoting the profession. The goals of the Society are diverse and include:. ...
The first of the modern treatments for heart failure lay in the development of assist devices. These paved the way for the development of more complicated mechanisms such as the TAH. These apparatus do not act to take over the action of the heart; rather, they reduce the stress exerted on the heart, allowing it to rest and recover. Development of these devices accelerated in the 1960s and 70s due to complications and mortality associated with early total HTxs.8 The evolution of pump technology brought about two main types of devices: pulsatile LVADs, where blood is pumped through the internal device via an external pump mimicking the action of the heart; and, continuous flow pumps (axial and centrifugal), in which a magnetically controlled rotor forces blood through the device. It should be noted that when a continuous flow pump is implanted the patient will employ an abnormal non-pulsatile state, posing difficulties in clinical measurement of pulse and blood pressure. Both types of devices are ...
The TAH is attached to your hearts upper chambers-the atria (AY-tree-uh). Between the TAH and the atria are mechanical valves that work like the hearts own valves. Valves control the flow of blood in the heart. (For more information, go to the Health Topics How the Heart Works article.). Currently, the two types of TAHs are the CardioWest and the AbioCor. The main difference between these TAHs is that the CardioWest is connected to an outside power source and the AbioCor isnt.. The CardioWest has tubes that, through holes in the abdomen, run from inside the chest to an outside power source.. ...
There are various artificial heart valves available for children, but they have one essential drawback: they need to be replaced because the children are still growing. The artificial valve, on the other hand, remains the same size - and subsequently becomes too small. This is why an artificial heart valve that grows over time would be ideal.
So for an update on my dads situation....He was put on the transplant list for a new heart on Thursday. Extremely scary!!!! His heart is only working at a 7% right now. He is being discharged and sent home wearing a life vest. Which i didnt know what that was but working in the medical field at the hosp. I did some research, asked my ANAM and she told me pretty much it is a Defibrillator that just sticks to you with leads kind of like an EKG or heart monitor when your in the hosp. It is temp. for right now but he is at risk for Cardiac Arrest so if his heart becomes arrythemic and he is not awake to disarm it the life vest is there to shock his heart. They are hoping with meds that his heart will strengthen on its own but they would like in a few months to put in A Ventricular Assist Device (VAD)which is implanted surgically and provides partial or total circulatory assistance to the natural heart. Since 1969, VADs have been used as support to sustain a patients life and maintain their other ...
So for an update on my dads situation....He was put on the transplant list for a new heart on Thursday. Extremely scary!!!! His heart is only working at a 7% right now. He is being discharged and sent home wearing a life vest. Which i didnt know what that was but working in the medical field at the hosp. I did some research, asked my ANAM and she told me pretty much it is a Defibrillator that just sticks to you with leads kind of like an EKG or heart monitor when your in the hosp. It is temp. for right now but he is at risk for Cardiac Arrest so if his heart becomes arrythemic and he is not awake to disarm it the life vest is there to shock his heart. They are hoping with meds that his heart will strengthen on its own but they would like in a few months to put in A Ventricular Assist Device (VAD)which is implanted surgically and provides partial or total circulatory assistance to the natural heart. Since 1969, VADs have been used as support to sustain a patients life and maintain their other ...
Counterpulsation methods and systems for assisting the heart of a patient involve, for example, coordinating the operation of a pulsatile pump to suction blood from an artery through a blood flow conduit while the heart is in systole and expel the blood into the blood flow conduit and the artery while the heart is in diastole.
An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for people with advanced heart failure who had surgery to implant mechanical circulatory support devices.
Datascope has received a complaint that has been associated with a patient death due to the failure of the device to initiate therapy.. This complaint involved a CS300 IABP that did not pump due to an electrical test failure code #58 (power up vent tests fail), maintenance code #3, and an autofill failure. An electrical test failure code #58 is caused by a solenoid valve requiring more power than the solenoid driver board can deliver to open the valve.. There are approximately 12,000 affected units sold globally. The affected IABP units were distributed in the U.S. and worldwide (in over 100 countries). Affected units were distributed between March 23, 2003, and December 11, 2013. Units distributed after December 11, 2013, are not affected by the field correction.. A service representative from Datascope will be replacing the defective solenoid driver boards. Customers having affected IABP unit(s) will be contacted by a representative of the Maquet/Getinge Service Team to schedule on-site ...
Adequate Systemic Perfusion Maintained by a CentriMag during Acute Heart Failure. Favaloro, Roberto R.; Bertolotti, Alejandro; Diez, Mirta; Favaloro, Liliana; Gomez, Carmen; Peradejordi, Margarita; Trentadue, Julio; Hellman, Lorena; Arzani, Yanina; Otero, Pilar Varela // Texas Heart Institute Journal;2008, Vol. 35 Issue 3, p334 Mechanical circulatory support during severe acute heart failure presents options for myocardial recovery or cardiac replacement. Short-term circulatory support with the newest generation of magnetically levitated centrifugal-flow pumps affords several potential advantages. Herein, we present... ...
Support device for the human vertebral column having an elongated dorsally implantable holding device, at least two pedicle screws which have a head and a threaded shank and the head of which is mount
A wearable kneel-sit support device includes a U-shaped body that is pivotally connected to both a seat member and a base member. A linking member connects the seat member and the base member, such that moving one of the seat member and the base member causes both the seat member and the base member to rotate from a folded position adjacent the leg of the user to an unfolded position. In the unfol
This report features 12 companies, including Ventracor, CardiacAssist, CorWave, Leviticus Cardio, Berlin Heart, Jarvik Heart, St. Jude Medical, ReliantHeart, Medtronic
Artificial heart patient Michael Drummond, nearly fully recovered from a series of mild strokes, sat up in a chair to watch television Friday while attempts were made to locate a donor heart for an
Surgeons at a Paris hospital have implanted a revolutionary new artificial heart which is designed to stay in the body for five years. Similar devices have been used for decades as a short-term measure, but patients can keep the new one for longer as they await donors.
A 74-year-old man who received a self-contained artificial heart has died, eight weeks after the device was implanted, doctors said Thursday.
Of the 24809 adults listed for HT, we identified 677 patients (2.7%) with the diagnosis of FDCM. Compared to patients with NICM and ICM, FDCM patients were younger (FDCM 43.9 ± 13.5 vs NICM 50.9 ± 12.3, P , 0.001, vs ICM 58.5 ± 8.1, P , 0.001), more frequently listed as status 2 (FDCM 35.2% vs NICM 26.5%, P , 0.001), with significantly lower left ventricular assist device (LVAD) utilization (FDCM 18.4% vs NICM 25.1%, P , 0.001; vs ICM 25.6%, P , 0.001), but higher use of total artificial heart (FDCM 1.3% vs NICM 0.6%, P = 0.039; vsICM 0.4%, P = 0.002). Additionally, patients with FDCM were less frequently delisted for clinical deterioration or death and more likely to be transplanted compared to those with NICM [hazard ratio (HR): 0.617, 95% confidence interval (CI): 0.47-0.81; HR: 1.25, 95%CI: 1.14-1.37, respectively], and ICM (HR: 0.5, 95%CI: 0.38-0.66; HR: 1.18, 95%CI: 1.08-1.3, respectively). There was more frequent rejection among patients with FDCM (FDCM 11.4% vs NICM 9.8%, P = 0.28; vs ...
BACKGROUND: The number of heart transplants performed is limited by organ availability and is managed by the United Network for Organ Sharing (UNOS). Efforts are underway to make organ disbursement more equitable as demand increases. HYPOTHESIS: Significant variation exists in contemporary patterns of care, wait times, and outcomes among patients undergoing heart transplantation across UNOS regions. METHODS: We identified adult patients undergoing first, single-organ heart transplantation between January 2006 and December 2014 in the UNOS dataset and compared sociodemographic and clinical profiles, wait times, use of mechanical circulatory support (MCS), status at time of transplantation, and 1-year survival across UNOS regions ...
Under the agreement, TFX will provide its complete lineup of Arrow Intra-Aortic Balloon Catheters and WAVE Intra-Aortic Balloon Pumps to more than 65,000 members served by Novation
Convenient access to care through the Center for Advanced Heart and Lung Disease. We offer a mechanical circulatory support program; chronic hemodynamic support and transplantation; cardiac rehabilitation; patient education that is focused on medication, lifestyle adjustments and nutrition; and patient and family support programs ...
The CCTN-CHFS Research Competition was created in 2017 to recognize individuals for outstanding research in the field of heart failure, transplantation, or mechanical circulatory support (MCS). Applicants submitting their research abstract to the Canadian Cardiovascular Congress (CCC) will be given the opportunity to submit their abstract into the CCTN-CHFS Research Competition.. Eligibility Criteria: ...
AMSTERDAM -- One year out, intra-aortic balloon pump (IABP) support still did not reduce mortality among patients with acute MI complicated by cardiogenic shock, extended follow-up of the IABP-SHOCK I
An artificial ventricle for use as part of a total artificial heart for implantation within a living being as part of its circulatory system. The ventricle includes a soft and flexible blood pumping sac which can be collapsed to the substantially flattened, squeezed or rolled-up structure of much reduced size. The sac includes inlet and outlet ports to permit the flow of blood therethrough and is contained within a semi-rigid and removable enclosure which provides pumping means for driving blood flow through the ventricle. The semi-rigid shell includes open and closed configurations to allow emplacement of the shell around an attached ventricle already sutured in place as part of the circulatory system. Removal of the rigid shell is likewise feasible without disturbing the attached ventricle.
The SynCardia CardioWest temporary Total Artificial Heart (TAH-t) System is a pulsatile biventricular device that replaces a patients native ventricles and valves, and pumps blood to both pulmonary and systemic circulation. The system consists of the implantable CardioWest TAH-t and an external pneumatic driver connected by drivelines ...
Thrombus with Infection in Total Artificial Heart Animals (pages 371-376). Bang Y. Chiang, Donald B. Olsen, Gregory L. Burns, George M. Pantalos, Scott Everett, Pamela A. Dew, Eisuke Tatsumi, John R. Rowles and Fazal Mohammad. Version of Record online: 12 NOV 2008 , DOI: 10.1111/j.1525-1594.1992.tb00534.x. ...
The cookies allow us to identify your computer and find out details about your last visit. They remembering whether youve visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer. ...
Abiomed, Inc. is reporting that the FDA has issued 510(k) clearance for the companys Impella® 5.0 and Impella® LD Circulatory Support Devices. The
I loved it all! Sorry I hadnt reviewed much I really just started back to reading since I had taken a break from the site since I graduated from high school so sorry! *tears* This was amazing and I love it completely! I enjoyed it greatly and again sorry for the lateness, I just recently started updating my own stories as well. I hope you do update your other story Weak I miss it so much! Thanks for the special thanks! Im glad I helped you out with bringing smiles! _ hehe ...
Designed to securely attach both the sheath seal and Y suture pads of the Maquet Intra-Aortic Balloon Catheters to a patients thigh when IAB therapy is indicated.
Medical grade battery for DataScope - Mindray 95 Intra-Aorta Balloon Pump replaces manufacturer part 0146-00-0039. The output of this battery is 12.0V and the capacity is 18.0Ah. Batteryheads part LIF00928-1
TY - JOUR. T1 - Outcomes of the first international conference on pediatric mechanical circulatory support systems and pediatric cardiopulmonary perfusion. AU - Ündar, Akif. PY - 2006/1/1. Y1 - 2006/1/1. UR - http://www.scopus.com/inward/record.url?scp=33645749751&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=33645749751&partnerID=8YFLogxK. U2 - 10.1097/01.mat.0000201799.41378.78. DO - 10.1097/01.mat.0000201799.41378.78. M3 - Article. C2 - 16436882. AN - SCOPUS:33645749751. VL - 52. SP - 1. EP - 3. JO - ASAIO Journal. JF - ASAIO Journal. SN - 1058-2916. IS - 1. ER - ...
This brief CME publication explores clinical evidence for the use of left ventricular assist devices (LVADs) in patients with advanced heart failure. It also reviews the evolution of LVADs from first-generation to third-generation devices and discusses therapeutic indications and contraindications for LVADs. Additionally, in a short introductory video, a faculty expert discusses approaches for identifying patients who may be candidates for LVADs and the evolving role of these devices in the treatment of advanced heart failure.
Dr Maltais is currently an Associate Professor of Surgery in the Department of Cardiovascular Surgery at the Mayo Clinic in Rochester, Minnesota. He is the Chair of Practice, the Director of the Mechanical Circulatory Support (MCS) Program, and the Physician Leader for the LVAD Manage to Reimbursement enterprise-wide project. Previously, he had been at Vanderbilt University Medical Center (Nashville, TN), where he was the Surgical Director of the Heart Transplantation and Mechanical Circulatory Support Programs, Director of the Translational and Clinical Research Programs, Surgical Director of the ECMO Shock Team, and Co-Director of the residency program in the Department of Cardiac Surgery. Under his leadership, Dr Maltais has helped Vanderbilt become one of the premiere advanced heart failure programs in the United States performing over 70 heart transplantations in 2017 and implanting up to almost 100 durable mechanical devices. Dr Maltais has been a member of the ISHLT society, and he has ...
Myocarditis has an estimated incidence of 10 in 100 000 and is the most common acquired cause of cardiac failure requiring heart transplant in children.[1,2] Viruses form the main aetiological basis, with Coxsackie B virus being responsible for the majority of viral myocarditis cases.[2] The clinical presentation of myocarditis varies from mild fever, flu-like symptoms and malaise to complete cardiovascular collapse, being acute fulminant myocarditis (AFM).[3] AFM is characterised by sudden onset of severe and extensive haemodynamic compromise.[4] Complete atrioventricular heart block (CAVB) is a rare complication of myocarditis and contributes to further haemodynamic compromise.[5] Although more dramatic in its presentation, if it is managed aggressively with mechanical circulatory support, affected patients may have full recovery and less risk of developing dilated cardiomyopathy.[4] In a limited-resource setting where mechanical cardiac support is not available, immediate recognition, ...
New life-saving treatments for Heart failure in clinical trial on Confirmation Trial of the Acorn CorCap Cardiac Support Device (CSD) at the Same Time as Mitral Valve Repair
The Acorn CorCap Cardiac Support Device (CSD) is a new therapy for the treatment of heart failure that is designed to reduce left ventricular dilation, which is one of the most important pathophysiological mechanisms underlying the clinical syndrome of heart failure. The Acorn CorCap CSD is intended to reduce wall stress and support the heart, in order to prevent further dilation that is associated with progressive heart failure. It is designed to result in reduced left ventricular size and improve left ventricluar function, which should result in improved patient functional status.. The purpose of the study is to provide confirmatory data to demonstrate an improved benefit-risk profile in support of a Pre-Market Approval (PMA) application for the Acorn CorCap CSD when placed concomitant to Mitral Valve Repair/Replacement (MVR).. The primary efficacy objective is to evaluate patient functional status after 6 months of follow-up. The safety endpoint is perioperative (30 day) mortality. ...
Cardiogenic shock complicating an acute coronary syndrome is observed in up to 10% of patients and is associated with high mortality still approaching 50%. The extent of ischaemic myocardium has a profound impact on the initial, in-hospital, and post-discharge management and prognosis of the cardiogenic shock patient. Careful risk assessment for each patient, based on clinical criteria, is mandatory, to decide appropriately regarding revascularization by primary percutaneous coronary intervention or coronary artery bypass grafting, drug treatment by inotropes and vasopressors, mechanical left ventricular support, additional intensive care treatment, triage among alternative hospital care levels, and allocation of clinical resources. This chapter will outline the underlying causes and diagnostic criteria, pathophysiology, and treatment of cardiogenic shock complicating acute coronary syndromes, including mechanical complications and shock from right heart failure. There will be a major focus on potential

artificial heart facts, information, pictures | Encyclopedia.com articles about artificial heartartificial heart facts, information, pictures | Encyclopedia.com articles about artificial heart

If a clot enters the circulation of the brain the result is often a stroke. Anticoagulant drugs are required to minimize this ... "The Need for Easier Manufacturing of Artificial Hearts and Assist Devices and How This Need Can Be Met by the Vacuum Molding ... Occasionally, use of a left heart assist device has been temporary, where the heart has been affected by a condition which is ... These replacements may be in the form of a left ventricle assist device or a total artificial heart, depending on the patients ...
more infohttps://www.encyclopedia.com/medicine/divisions-diagnostics-and-procedures/medicine/artificial-heart

Ventricular Assist Device (VAD) - Jarvik Heart Inc.Ventricular Assist Device (VAD) - Jarvik Heart Inc.

... doctors and researchers have developed a new generation of devices to mechanically assist blood circulation. Some of these ... Ventricular Assist Device (VAD). (Also known as: Heart Assist Pump, Heart Pump, and Mechanical Circulatory Support System) ... The Jarvik 2000® Ventricular Assist Device is sometimes called a "booster" pump. Implanted inside the intact biological heart, ... Assist devices are therefore markedly different from their total artificial heart predecessors. ...
more infohttps://www.jarvikheart.com/treatment-options/implantable-devices/left-ventricular-assist-device-lvad/

Assisted circulation - definition of assisted circulation by The Free DictionaryAssisted circulation - definition of assisted circulation by The Free Dictionary

assisted circulation synonyms, assisted circulation pronunciation, assisted circulation translation, English dictionary ... definition of assisted circulation. n. 1. Movement in a circle or circuit, especially the movement of blood through bodily ... to be in circulation [money] → être en circulation. to be out of circulation, to be withdrawn from circulation [money] → être ... pulmonary circulation - circulation of blood between the heart and the lungs. vitelline circulation - circulation of blood ...
more infohttps://www.thefreedictionary.com/assisted+circulation

Performance Goals for Dispatcher-Assisted CPR | CirculationPerformance Goals for Dispatcher-Assisted CPR | Circulation

Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person ... Your Name) thought you would like to see the Circulation web site. ... Circulation. 2013;CIRCULATIONAHA.113.005496, originally published August 27, 2013 https://doi.org/10.1161/CIRCULATIONAHA. ... Circulation. 2013;CIRCULATIONAHA.113.005496, originally published August 27, 2013 https://doi.org/10.1161/CIRCULATIONAHA. ...
more infohttp://circ.ahajournals.org/content/early/2013/08/23/CIRCULATIONAHA.113.005496

Performance Goals for Dispatcher-Assisted Cardiopulmonary Resuscitation | CirculationPerformance Goals for Dispatcher-Assisted Cardiopulmonary Resuscitation | Circulation

Heart disease and stroke statistics-2013 update: a report from the American Heart Association. Circulation. 2013;127:e6-e245. ... Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person ... In this issue of Circulation, Lewis and Eisenberg12 report their analysis of dispatch recordings and EMS records from 476 out- ... Dispatcher-assisted cardiopulmonary resuscitation: time to identify cardiac arrest and deliver chest compression instructions. ...
more infohttp://circ.ahajournals.org/content/128/14/1490

Design of a right ventricular mock circulation loop as a test bench for right ventricular assist devices : Biomedical...Design of a right ventricular mock circulation loop as a test bench for right ventricular assist devices : Biomedical...

An essential contribution to the process of developing right ventricular assist devices (RVADs) is the in vitro test bench, ... a right heart mock circulation loop (MCL) was developed. Incorporating an anatomically shaped silicone RV and a silicone atrium ... Design of a right ventricular mock circulation loop as a test bench for right ventricular assist devices ... Design of a right ventricular mock circulation loop as a test bench for right ventricular assist devices. ...
more infohttps://www.degruyter.com/view/j/bmte.2017.62.issue-2/bmt-2016-0104/bmt-2016-0104.xml?rskey=PefgV8&result=7

Dynamic Left Ventricular Assist Device Inflow Obstruction | Circulation: Heart FailureDynamic Left Ventricular Assist Device Inflow Obstruction | Circulation: Heart Failure

Dynamic Left Ventricular Assist Device Inflow Obstruction. Edo Y. Birati, James N. Kirkpatrick, J. Eduardo Rame, Rupa Bala, ... Dynamic Left Ventricular Assist Device Inflow Obstruction. Edo Y. Birati, James N. Kirkpatrick, J. Eduardo Rame, Rupa Bala and ... Dynamic Left Ventricular Assist Device Inflow Obstruction. Edo Y. Birati, James N. Kirkpatrick, J. Eduardo Rame, Rupa Bala and ... Your Name) thought you would like to see the Circulation: Heart Failure web site. ...
more infohttp://circheartfailure.ahajournals.org/content/7/1/225.short?rss=1

Outflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device | Circulation: Heart FailureOutflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device | Circulation: Heart Failure

Outflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device. Juan G. Duero Posada, Yasbanoo Moayedi, Mosaad ... Outflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device. Juan G. Duero Posada, Yasbanoo Moayedi, Mosaad ... Outflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device. Juan G. Duero Posada, Yasbanoo Moayedi, Mosaad ... Continuous-flow ventricular assist devices have demonstrated clinical superiority compared with the first-generation pulsatile ...
more infohttp://circheartfailure.ahajournals.org/content/10/9/e004275

KAKEN - Research Projects | Optimization of skeletal muscle for actuator of assisted circulation (KAKENHI-PROJECT-07457302)KAKEN - Research Projects | Optimization of skeletal muscle for actuator of assisted circulation (KAKENHI-PROJECT-07457302)

We constructed SMV uisng both LDMs and evaluated the basic performance of SMV with mock circulation. Stroke work (SW) was ... Publications] Toda K., Nakatani T., et al.: Effect of cardiomyoplasty for right heart assist on right heart failure during ... left ventricular assistance Application of skeletal muscle to heart assist. (in press).. *. Description. 「研究成果報告書概要(欧文)」より ... muscle after preconditioning is one of the important problems in application of skeletal muscle for assited circulation. To ...
more infohttps://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07457302/

Life Plus Circulation Formula L Arginine, Muira Puama Assists Sexual Function, HGH, Healthy Blood Pressure.Life Plus Circulation Formula L Arginine, Muira Puama Assists Sexual Function, HGH, Healthy Blood Pressure.

... arginine enhances healthy circulation. Also stimulates HGH -Human Growth Hormone - Circulation Formula enhances circulation and ... Circulation Formula - Stimulate Circulation Safely and Successfully Circulation Formula is a premium formula that enhances ... Firm up your circulation with Circulation Formula!. Product Information Sheet. CIRCULATION FORMULA. ... Contains L-Arginine to Support Circulation*. Circulation Formula is a premium scientific formulation that includes the amino ...
more infohttp://lifeplusvitamins.com/circulex.htm

Fluid structure interaction model analysis of cerebrospinal fluid circulation in patients with continuous-flow left ventricular...Fluid structure interaction model analysis of cerebrospinal fluid circulation in patients with continuous-flow left ventricular...

... interaction model analysis of cerebrospinal fluid circulation in patients with continuous-flow left ventricular assist devices ... The current 1-dimensional fluid structure interaction model (FSI) for understanding cerebrospinal fluid (CSF) circulation ... requires pulsatility as a precondition and has not been applied to patients with continuous-flow left ventricular assist ...
more infohttp://www.artificial-organs.com/article/4ba1846b-0e7a-4235-96dc-7f746f0ce4b0

Best Blood Pressure Support Supplement, PERFECT PRESSURE - Advanced Natural Cardiovascular Health Aid. Assist in Blood...Best Blood Pressure Support Supplement, PERFECT PRESSURE - Advanced Natural Cardiovascular Health Aid. Assist in Blood...

Assist in Blood Circulation. Effective Formula with Hawthorn Berry, Garlic & More. 60 Capsules. ... Written by Albert Crenshaw Posted in Health Products Tagged with Advanced, Aid., Assist, Berry, Best, Blood, Capsules, ... These ingredients are thought to temporarily relieve symptoms such as stress and slow blood circulation. ... L-Arginine 500mg 250 Caps - Cardiovascular Health Support Formula - L Arginine Enhances Circulation - Lifetime 100% ...
more infohttp://www.curehelp.com/health-blog/best-blood-pressure-support-supplement-perfect-pressure-advanced-natural-cardiovascular-health-aid-assist-in-blood-circulation-effective-formula-with-hawthorn-berry-garlic-more-60-capsule/

Chapter 235. Cardiac Transplantation and Prolonged Assisted Circulation | Harrisons Principles of Internal Medicine, 18e |...Chapter 235. Cardiac Transplantation and Prolonged Assisted Circulation | Harrison's Principles of Internal Medicine, 18e |...

Cardiac Transplantation and Prolonged Assisted Circulation." Harrisons Principles of Internal Medicine, 18e Longo DL, Fauci AS ... Cardiac Transplantation and Prolonged Assisted Circulation. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J ... the option of permanent mechanical assistance of the circulation. In the future, it is possible that genetic modulation of ...
more infohttps://accesspharmacy.mhmedical.com/content.aspx?bookid=331§ionid=40727010

MiessesHerbs.com | Circulation AssistMiessesHerbs.com | Circulation Assist

A to Z Mens Health Womens Health Senior Health Body System Support Circulatory System and Liver Restorer Circulation Assist ... May increase circulation to the extremities. * Provides essential fatty acids, which benefit heart health.. [Product Details ... Improves overall circulation. • Aids in the regulation of the glandular system. • Provides extra energy. • Helps regulate blood ... Enhances bodily function by improving blood quality and circulation. •Helps strengthen the immune system. •Soothes the nerves ...
more infohttp://miessesherbs.com/index.php?option=com_virtuemart&page=shop.browse&category_id=16&Itemid=53

April 1963 - Volume 9 - Issue 1 : ASAIO JournalApril 1963 - Volume 9 - Issue 1 : ASAIO Journal

ASSISTED CIRCULATION: V. THE USE OF THE LUNGS AS A PUMP. A METHOD FOR ASSISTING PULMONARY BLOOD FLOW BY VARYING AIRWAY PRESSURE ... INFLUENCE OF ASSISTED CIRCULATION UPON THE SIZE OF CARDIAC CAVITIES. Salgado, C. R.; Luethy, E.; Franch, R. H.; More ... PROLONGED ASSISTED CIRCULATION DURING AND AFTER HEART OR AORTIC SURGERY. Liotta, Domingo; Hall, William C.; Henly, Walter S.; ... PROLONGED ASSISTED CIRCULATION DURING AND AFTER HEART OR AORTIC SURGERY PDF Only. ...
more infohttps://journals.lww.com/asaiojournal/toc/1963/09000

Stony Brook Physician First On LI To Use Minimally Invasive Robotically-Assisted Surgery For ENT Procedures - Healthcanal.com :...Stony Brook Physician First On LI To Use Minimally Invasive Robotically-Assisted Surgery For ENT Procedures - Healthcanal.com :...

Blood, Heart and Circulation. 02/14/2020 Blood, Heart and Circulation Cocoa could bring sweet relief to walking pain for people ... After robotic-assisted surgery, many patients experience significantly less pain, less blood loss, less scarring, and shorter ... Stony Brook Physician First On LI To Use Minimally Invasive Robotically-Assisted Surgery For ENT Procedures. ...
more infohttps://www.healthcanal.com/surgery-rehabilitation/15675-stony-brook-physician-first-on-li-to-use-minimally-invasive-robotically-assisted-surgery-for-ent-procedures.html

Long-term study: Robot-assisted prostate surgery is safe - Healthcanal.com : Healthcanal.comLong-term study: Robot-assisted prostate surgery is safe - Healthcanal.com : Healthcanal.com

Blood, Heart and Circulation. 12/13/2017 Heart disease Genomic blood test predicts survival rates after surgery for advanced ... Henry Fords robot-assisted urology program uses a surgeon-controlled robot, the da Vinci minimally invasive surgery system. ... Henry Ford Hospital pioneered the use of robots to assist surgeons in the delicate procedure, and the new study notes that ... Home Surgery and Rehabilitation Long-term study: Robot-assisted prostate surgery is safe ...
more infohttps://www.healthcanal.com/surgery-rehabilitation/15528-long-term-study-robot-assisted-prostate-surgery-is-safe.html

OSA | Blood cell assisted in vivo Particle Image Velocimetry using the confocal laser scanning microscopeOSA | Blood cell assisted in vivo Particle Image Velocimetry using the confocal laser scanning microscope

Circulation (1). A. J. Lee, P. I. Mowbray, G. D. Lowe, A. Rumley, F. G. Fowkes, and P. L. Allan, "Blood viscosity and elevated ... Blood cell assisted in vivo Particle Image Velocimetry using the confocal laser scanning microscope Sung Min Choi, Wi Han Kim, ... Sung Min Choi, Wi Han Kim, Daniel Côté, Cheol-Woo Park, and Ho Lee, "Blood cell assisted in vivo Particle Image Velocimetry ... We demonstrated the feasibility of blood cell assisted in vivo Particle Image Velocimetry using confocal microscopy. Blood flow ...
more infohttps://www.osapublishing.org/oe/abstract.cfm?URI=oe-19-5-4357

Technology and Health Care - Volume 5, issue 6 - Journals - IOS PressTechnology and Health Care - Volume 5, issue 6 - Journals - IOS Press

Assisted circulation devices Authors: Clemente, Fabrizio , Ferrari, Gian Franco , De Lazzari, Claudio , Tosti, Giancarlo ... Keywords: Quality and safety of medical devices, technical standards, heart assist devices, benchmark, European Directives 90/ ... biomedical devices and the presentation of the set up of a technical standard for mechanical heart assist devices. Show more ...
more infohttps://content.iospress.com/journals/technology-and-health-care/5/6

Ventricular assist device: MedlinePlus Medical EncyclopediaVentricular assist device: MedlinePlus Medical Encyclopedia

Ventricular assist devices (VADs) help your heart pump blood from one of the main pumping chambers to the rest of your body or ... Circulation. 2012;126(22):2648-2667. PMID: 23109468 www.ncbi.nlm.nih.gov/pubmed/23109468. ... VAD; RVAD; LVAD; BVAD; Right ventricular assist device; Left ventricular assist device; Biventricular assist device; Heart pump ... Left ventricular assist system; LVAS; Implantable ventricular assist device; Heart failure - VAD; Cardiomyopathy - VAD ...
more infohttps://medlineplus.gov/ency/article/007268.htm

History of Durable Mechanical Circulatory Assist Devices | SpringerLinkHistory of Durable Mechanical Circulatory Assist Devices | SpringerLink

Biventricular assist device utilization for patients with morbid congestive heart failure. Circulation. 2005;112:I-65-72.Google ... Prolonged assisted circulation during and after cardiac or aortic surgery: prolonged partial left ventricular bypass by means ... Implantable left ventricular assist devices. N Engl J Med. 1998;339:1522-33.CrossRefPubMedGoogle Scholar ... Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435-43.CrossRefPubMed ...
more infohttps://link.springer.com/chapter/10.1007%2F978-3-319-74657-9_6

Patent US4995857 - Left ventricular assist device and method for temporary and permanent procedures - Google PatentsPatent US4995857 - Left ventricular assist device and method for temporary and permanent procedures - Google Patents

A left ventricular assist device and method is utilized to relieve the hemodynamic burden on a diseased left ventricle in the ... Implantable heart assist system. WO1999060941A1 *. 26 May 1999. 2 Dec 1999. Circulation, Inc.. Apparatus for providing coronary ... Ventricular-assist method and apparatus. US6428464. 9 Apr 1999. 6 Aug 2002. Orqis Medical Corporation. Implantable heart assist ... Staged implantation of ventricular assist devices. US20070197854 *. 26 Jan 2007. 23 Aug 2007. Circulite, Inc.. Heart assist ...
more infohttp://www.google.ca/patents/US4995857

Implantable heart assist system and method of applying same - Thoratec CorporationImplantable heart assist system and method of applying same - Thoratec Corporation

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any ... Implantable mechanical system for assisting blood circulation. October, 1995. Liotta. 5449342. Apparatus for assisting blood ... Apparatus for mechanically assisting circulation of the blood in the human body. 1977-07-12. Thoma. ... Cardiac replacement and assist devices. 1977-01-25. Runge. 3995617. Heart assist method and catheter. 1976-12-07. Watkins et al ...
more infohttp://www.freepatentsonline.com/8900115.html

Late effects of cardiomyoplasty on left v... & related info | MendeleyLate effects of cardiomyoplasty on left v... & related info | Mendeley

Circulation. BACKGROUND: Dynamic cardiomyoplasty is a relatively new surgical procedure proposed for treatment of severe ... Assisted Circulation. *Cardiac Catheterization. *Cardiomyopathy, Dilated. *Echocardiography, Doppler. *Electric Stimulation ...
more infohttps://www.mendeley.com/research-papers/late-effects-cardiomyoplasty-left-ventricular-mechanics-diastolic-filling/

Vascular - Books SitemapVascular - Books Sitemap

Assisted Circulation 3 - 1989 - 621 pages. Atherosclerosis by Christian Weber, Oliver Soehnlein - 2012 - 492 pages. ... Collateral circulation by Daniel Paul Quiring - 1949 - 142 pages. Collateral circulation in clinical surgery by Donald Eugene ... Coronary circulation by Fumihiko Kajiya - 1990 - 336 pages. Coronary Heart Surgery by Helmut Roskamm, Martin Schmuziger - 1979 ...
more infohttp://books.google.com/sitemap/Sitemap/Medical/Surgery/Vascular.html
  • 8 - 11 Until now, little has been known about how frequently these and other factors affect cardiac arrest recognition or provision of dispatcher-assisted chest compression instructions by 9-1-1 dispatchers. (ahajournals.org)
  • In this issue of Circulation , Lewis and Eisenberg 12 report their analysis of dispatch recordings and EMS records from 476 out-of-hospital cardiac arrest cases in King County, Washington, during 2011. (ahajournals.org)
  • Current therapeutic options are limited to cardiac transplantation (with the option of mechanical cardiac assistance as a "bridge" to transplantation) or (at least in theory) the option of permanent mechanical assistance of the circulation. (mhmedical.com)
  • Prolonged assisted circulation during and after cardiac or aortic surgery: prolonged partial left ventricular bypass by means of intracorporeal circulation. (springer.com)
  • An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. (freepatentsonline.com)
  • Liotta D, Hall CW, Henly WS, Beall AC, Cooley DA, De Bakey M (1963) Prolonged assisted circulation during and after cardiac or aortic surgery. (springer.com)
  • Liotta D, Hall CW, Henly WS, Cooley DA, Crawford ES, De Bakey ME (1963) Prolonged assisted circulation after cardiac or aortic surgery. (springer.com)
  • Some of the superior hypophyseal arteries form primary capillary beds in the hypothalamus and the veins draining those beds ramify again to form secondary capillary beds in the adenohypophysis (anterior lobe of the pituitary), thus forming a portal circulation (the hypothalamic-pituitary portal circulation). (tabers.com)
  • The findings, published online this month by the journal European Urology, follow an earlier Henry Ford study that found nearly 87 percent of patients whose cancerous prostates were removed by robot-assisted surgery had no recurrence of the disease after five years. (healthcanal.com)
  • Henry Ford's robot-assisted urology program uses a surgeon-controlled robot, the da Vinci minimally invasive surgery system. (healthcanal.com)
  • First generation ventricular assist devices were pulsatile in nature with a variety of designs and placement and were approved for use as a bridge to transplant and/or post-cardiotomy shock. (springer.com)