The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation.
The circulation of the BLOOD through the LUNGS.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
Recycling through liver by excretion in bile, reabsorption from intestines (INTESTINAL REABSORPTION) into portal circulation, passage back into liver, and re-excretion in bile.
The circulation of blood through the CORONARY VESSELS of the HEART.
The circulation of blood through the BLOOD VESSELS of the BRAIN.
The circulation of BLOOD, of both the mother and the FETUS, through the PLACENTA.
The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.
Determination of the shortest time interval between the injection of a substance in the vein and its arrival at some distant site in sufficient concentration to produce a recognizable end result. It represents approximately the inverse of the average velocity of blood flow between two points.
The circulation of BLOOD through the LIVER.
The flow of BLOOD through or around an organ or region of the body.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The circulation in a portion of the body of one individual of blood supplied from another individual.
Pumping that aids the natural activity of the heart. (Dorland, 27th ed)
Elements of limited time intervals, contributing to particular results or situations.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.
The circulation of the BLOOD through the vessels of the KIDNEY.
The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).
Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission.
Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.
Injections made into a vein for therapeutic or experimental purposes.
Localized or diffuse reduction in blood flow through the vertebrobasilar arterial system, which supplies the BRAIN STEM; CEREBELLUM; OCCIPITAL LOBE; medial TEMPORAL LOBE; and THALAMUS. Characteristic clinical features include SYNCOPE; lightheadedness; visual disturbances; and VERTIGO. BRAIN STEM INFARCTIONS or other BRAIN INFARCTION may be associated.
The vessels carrying blood away from the capillary beds.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
A procedure in which total right atrial or total caval blood flow is channeled directly into the pulmonary artery or into a small right ventricle that serves only as a conduit. The principal congenital malformations for which this operation is useful are TRICUSPID ATRESIA and single ventricle with pulmonary stenosis.
The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.
The vessels carrying blood away from the heart.
The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.
The arterial blood vessels supplying the CEREBRUM.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Treatment process involving the injection of fluid into an organ or tissue.
Drugs used to cause dilation of the blood vessels.
A system of vessels in which blood, after passing through one capillary bed, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Left bronchial arteries arise from the thoracic aorta, the right from the first aortic intercostal or the upper left bronchial artery; they supply the bronchi and the lower trachea.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Radiography of the vascular system of the brain after injection of a contrast medium.
The veins and arteries of the HEART.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
Central retinal artery and its branches. It arises from the ophthalmic artery, pierces the optic nerve and runs through its center, enters the eye through the porus opticus and branches to supply the retina.
Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.
The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.
Relatively complete absence of oxygen in one or more tissues.
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
The experimental joining of two individuals for the purpose of studying the effects of one on the other.
Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The blood vessels which supply and drain the RETINA.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of 8 days, and emits beta and gamma rays. It is used as a diagnostic aid in blood volume determination. (from Merck Index, 11th ed)
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
The relationship between the dose of an administered drug and the response of the organism to the drug.
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Delivery of drugs into an artery.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.
A fetal blood vessel connecting the pulmonary artery with the descending aorta.
A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.
Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days.
Specialized arterial vessels in the umbilical cord. They carry waste and deoxygenated blood from the FETUS to the mother via the PLACENTA. In humans, there are usually two umbilical arteries but sometimes one.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
NECROSIS induced by ISCHEMIA in the POSTERIOR CEREBRAL ARTERY distribution system which supplies portions of the BRAIN STEM; the THALAMUS; TEMPORAL LOBE, and OCCIPITAL LOBE. Depending on the size and location of infarction, clinical features include OLFACTION DISORDERS and visual problems (AGNOSIA; ALEXIA; HEMIANOPSIA).
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
Radiography of blood vessels after injection of a contrast medium.
The venous pressure measured in the PORTAL VEIN.
The hollow, muscular organ that maintains the circulation of the blood.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.
The rate dynamics in chemical or physical systems.
The minute vessels that connect the arterioles and venules.
Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
A system of organs and tissues that process and transport immune cells and LYMPH.
Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.
The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.
Drugs used to cause constriction of the blood vessels.
The interstitial fluid that is in the LYMPHATIC SYSTEM.
Artery formed by the bifurcation of the BASILAR ARTERY. Branches of the posterior cerebral artery supply portions of the OCCIPITAL LOBE; PARIETAL LOBE; inferior temporal gyrus, brainstem, and CHOROID PLEXUS.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
Measurement of oxygen and carbon dioxide in the blood.
The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.
The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.
A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.
Artery originating from the internal carotid artery and distributing to the eye, orbit and adjacent facial structures.
A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
An infant during the first month after birth.
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.
The smallest divisions of the arteries located between the muscular arteries and the capillaries.
The innermost layer of the three meninges covering the brain and spinal cord. It is the fine vascular membrane that lies under the ARACHNOID and the DURA MATER.
Mononuclear cells with pronounced phagocytic ability that are distributed extensively in lymphoid and other organs. It includes MACROPHAGES and their precursors; PHAGOCYTES; KUPFFER CELLS; HISTIOCYTES; DENDRITIC CELLS; LANGERHANS CELLS; and MICROGLIA. The term mononuclear phagocyte system has replaced the former reticuloendothelial system, which also included less active phagocytic cells such as fibroblasts and endothelial cells. (From Illustrated Dictionary of Immunology, 2d ed.)
The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
The flow of water in enviromental bodies of water such as rivers, oceans, water supplies, aquariums, etc. It includes currents, tides, and waves.
Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.
Apparatus that provides mechanical circulatory support during open-heart surgery, by passing the heart to facilitate surgery on the organ. The basic function of the machine is to oxygenate the body's venous supply of blood and then pump it back into the arterial system. The machine also provides intracardiac suction, filtration, and temperature control. Some of the more important components of these machines include pumps, oxygenators, temperature regulators, and filters. (UMDNS, 1999)
The first of four extra-embryonic membranes to form during EMBRYOGENESIS. In REPTILES and BIRDS, it arises from endoderm and mesoderm to incorporate the EGG YOLK into the DIGESTIVE TRACT for nourishing the embryo. In placental MAMMALS, its nutritional function is vestigial; however, it is the source of INTESTINAL MUCOSA; BLOOD CELLS; and GERM CELLS. It is sometimes called the vitelline sac, which should not be confused with the VITELLINE MEMBRANE of the egg.
An encapsulated lymphatic organ through which venous blood filters.
Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
The processes whereby the internal environment of an organism tends to remain balanced and stable.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
Part of the arm in humans and primates extending from the ELBOW to the WRIST.
Blocking of a blood vessel by air bubbles that enter the circulatory system, usually after TRAUMA; surgical procedures, or changes in atmospheric pressure.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
The motion of air currents.
The main artery of the thigh, a continuation of the external iliac artery.
Diversion of the flow of blood from the entrance to the right atrium directly to the pulmonary arteries, avoiding the right atrium and right ventricle (Dorland, 28th ed). This a permanent procedure often performed to bypass a congenitally deformed right atrium or right ventricle.
The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A vessel that directly interconnects an artery and a vein, and that acts as a shunt to bypass the capillary bed. Not to be confused with surgical anastomosis, nor with arteriovenous fistula.
Devices which mechanically oxygenate venous blood extracorporeally. They are used in combination with one or more pumps for maintaining circulation during open heart surgery and for assisting the circulation in patients seriously ill with some cardiac and pulmonary disorders. (UMDNS, 1999)
The act of constricting.
Disease having a short and relatively severe course.
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Ultrasonography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.
A tricarbocyanine dye that is used diagnostically in liver function tests and to determine blood volume and cardiac output.
A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)
The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.
The vascular resistance to the flow of BLOOD through the CAPILLARIES portions of the peripheral vascular bed.
NECROSIS occurring in the ANTERIOR CEREBRAL ARTERY system, including branches such as Heubner's artery. These arteries supply blood to the medial and superior parts of the CEREBRAL HEMISPHERE, Infarction in the anterior cerebral artery usually results in sensory and motor impairment in the lower body.
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
Blood of the fetus. Exchange of nutrients and waste between the fetal and maternal blood occurs via the PLACENTA. The cord blood is blood contained in the umbilical vessels (UMBILICAL CORD) at the time of delivery.
Uptake of substances through the lining of the INTESTINES.
A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
The main trunk of the systemic arteries.
The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.
Exfoliate neoplastic cells circulating in the blood and associated with metastasizing tumors.
A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
Time period from 1601 through 1700 of the common era.
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.
Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.
Application of a ligature to tie a vessel or strangulate a part.
The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.
Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
The relationships of groups of organisms as reflected by their genetic makeup.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Artery formed by the bifurcation of the internal carotid artery (CAROTID ARTERY, INTERNAL). Branches of the anterior cerebral artery supply the CAUDATE NUCLEUS; INTERNAL CAPSULE; PUTAMEN; SEPTAL NUCLEI; GYRUS CINGULI; and surfaces of the FRONTAL LOBE and PARIETAL LOBE.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

Intraaortic balloon pumping assist following open heart surgery for coronary artery disease. (1/79)

Intraaortic balloon pump (IABP) assist was employed in 36 patients after surgical operation for coronary artery disease. In 31 patients, the aid of IABP was required because cardiopulmonary bypass could not be terminated without it. In three of these patients, IABP assist was started before the surgical procedure because these patients were in cardiogenic shock due to myocardial infarction. In the remaining five patients, IABP assist was applied for refractory cardiogenic shock in the early postoperative period. The overall survival rate was 58 percent. IABP assist was used in 13 patients with an ejection fraction of 0.1 to 0.2 (normal 0.7). Nine of these patients survived. From our experience, it would appear that this temporary mechanical circulatory support provides a significant advantage in saving patients who might otherwise die after surgical procedures involving the coronary artery.  (+info)

Effects of combined emergency percutaneous cardiopulmonary support and reperfusion treatment in patients with refractory ventricular fibrillation complicating acute myocardial infarction. (2/79)

OBJECT: We conducted a prospective study to determine whether or not combined emergency percutaneous cardiopulmonary support (PCPS) and coronary reperfusion treatment are useful for acute myocardial infarction (MI) patients with unsynchronized electric shock-resistive ventricular fibrillation (VF). PATIENTS AND METHODS: Thirty-two acute MI patients who lapsed into the refractory VF were entered into the study. Group 1 consisted of 19 patients with VF outside the hospital, and Group 2 consisted of 13 patients with VF immediately after arrival at the hospital. The primary endpoint was successful reperfusion, return of spontaneous circulation and good recovery without neurologic disability. RESULTS: The infarct-related arteries showed a significant difference between Groups 1 and 2. However, the two groups had similar rates of successful reperfusion (84.6% vs 94.7%, respectively) and return of spontaneous circulation (89.5% vs 84.6%, respectively). The rates of good recovery were similarly low in both groups (5.3% vs 15.4%, respectively). CONCLUSION: Combined emergency PCPS and reperfusion treatment produced high return of spontaneous circulation, however the neurologic outcome was low.  (+info)

Right ventricular infarction with cardiogenic shock treated with percutaneous cardiopulmonary support: a case report. (3/79)

A patient with a right ventricular infarction was resuscitated with percutaneous cardiopulmonary support (PCPS), after attempts at reperfusion, high-dose inotropic support and intra-aortic balloon counterpulsation failed to improve the hemodynamic compromise. Emergency PCPS improved the cardiogenic shock and the reduced right ventricular load, allowing the ischemic right ventricle to recover in the setting of unsuccessful reperfusion. This case demonstrates the use of PCPS as a hemodynamic support device for spontaneous recovery of the ischemic right ventricle. PCPS may be a potential therapy for patients with right ventricular infarction.  (+info)

Acute severe cardiac failure complicating myocardial infarction. Experience with 100 patients referred for consideration of mechanical left ventricular assistance. (4/79)

One hundred patients were referred with suspected acute cardiac failure following acute myocardial infarction. The diagnosis was confirmed in 72: 31 of these patients underwent elective medical treatment, with 2 survivors (6%); 41 were accepted for counter pulsation, but 9 died before this could be initiated and another 2 died shortly after vain attempts to pass the balloon catheter were abandoned; 30 patients underwent counterpulsation with 14 hospital survivors (47%). Survivor status was usually good. Results of counter pulsation were better in patients who were not shocked (with 5/5 survivors) than in those who were in shock (with 9 of 25 survivors). Results support the view that counterpulsation (alone or combined with corrective surgery) may play an important role in the complications of myocardial infarction provided intervention is early.  (+info)

Long-term results of arterial counterpulsation in acute severe cardiac failure complicating myocardial infarction. (5/79)

Thirty patients were discharged from hospital after treatment with arterial counterpulsation for acute severe heart failure complicating myocardial infarction. Seventeen patients had been in cardiogenic shock--13 with power failure alone, and 4 with a mechanical complication which required corrective surgery. Thirteen patients were in impending or 'preshock'. The follow-up period after infarction averaged 13-1 months. Results were good in 'preshock' patients, and in shocked patients with a surgically correctable mechanical complication. Results were poor in shocked patients with power failure alone. Counterpulsation has an important supportive role in the treatment of complicated myocardial infarction, provided that intervention is prompt and mechanical complications, if present, are corrected early.  (+info)

Percutaneous cardiopulmonary support as a bridge to emergency operation--two surviving cases. (6/79)

Two patients had percutaneous cardiopulmonary support (PCPS) used as a bridge to emergency surgery. A 66-year-old man admitted with profound cardiogenic shock underwent direct stenting under PCPS with the diagnosis of acute myocardial infarction of the left main trunk, with the intention of performing revascularization as soon as possible. Subsequently, double coronary artery bypass grafting was successfully accomplished. A 69-year-old woman, admitted with acute heart failure due to critical aortic stenosis, manifested cardiogenic shock while undergoing catheterization. PCPS was immediately instituted until the acute deterioration of her hemodynamic state could be reversed, and was continued uneventfully till aortic valve replacement was performed. These results suggest that the current PCPS system is an effective response to acute circulatory collapse and will contributed to the improved survival of patients.  (+info)

Intra-aortic balloon counterpulsation: potential for therapy in hemorrhagic shock with associated myocardial failure. (7/79)

After attaching appropriate monitoring devices enabling the measurement of the slope of the left ventricular function curve, left atrial pressure, mean aortic pressure, peak left ventricular pressure, and tension time index, three groups of ten dogs were subjected to varying periods of hemorrhagic shock until a slope of their ventricular function curve was reduced to either 75% (Group I), 50% (Group II), or 25% (Group III) of their baseline value. Resuscitation was attempted in all dogs by the intravenous infusion of shed blood plus additional balanced salt solution. This infusate was administered to maintain either the mean aortic pressure within 15 mm Hg of the baseline value or a left atrial pressure of 15 mm Hg, whichever occurred forst. One half of the dogs received, in addition, intra-aortic balloon counterpulsation. All dogs not receiving counterpulsation expired within two hours. There was no apparent effect of counterpulsation on Group I animals. Three of five animals (Group II) and four of five animals (Group III) receiving counterpulsation survived to the end of the experiment with significant (p smaller than .01) improvement in the parameters monitored. The utilization of counterpulsation as an adjunct to treatment in hemorrhagic shock is suggested.  (+info)

Twenty-four hour left ventricular bypass with a centrifugal blood pump. (8/79)

A new centrifugal blood pump system has been developed for left ventricular bypass by the addition of non-thrombogenic blood surface materials and an ultrathin-walled cannula for the retrograde cannulation of the left ventricle. Partial LV bypass at 3 to 6 L/min was undertaken in 55 calves without thoracotomy. In 20 it was continued for 24 hours, with 13 survivors who were eventually sacrificed. Eleven of the last 14 experiments were completed without mishap. Heparin was employed only during pump insertion. Hematologic changes were limited to moderate platelet depression, and tolerable hemolysis (average serum level 21 mg% in the last 13 experiments). Normal clotting parameters and the absence of significant fibrin split product formation correlated with the absence of gross thrombosis and few minor renal emboli observed at autopsy. This pump system appears to have several advantages over previously described equipment for LV bypass.  (+info)

METHODS AND RESULTS Eighteen dogs were instrumented with regional myocardial function sonomicrometers in the ischemic and control zones. The left anterior descending coronary artery just distal to the first diagonal branch was instrumented with a silk snare and Doppler flow probe. Additionally, pressure catheters were placed in the left atrial appendage, left ventricular apex, and ascending aorta for hemodynamic measurements. Regional myocardial blood flow was determined by using 15-microns radioactive microspheres. Measurements were made in the control state, immediately after coronary occlusion, at 1 and 2 hours after coronary occlusion, with reperfusion, and 1 hour after reperfusion. In treated animals, left ventricular assistance was maintained during the entire period of occlusion and reperfusion. The Hemopump was associated with a significant decrease in left ventricular systolic and diastolic pressure, whereas mean arterial pressure was maintained. Intra-aortic balloon counterpulsation ...
TY - JOUR. T1 - Prolonged mechanical support of the left ventricle.. AU - Pierce, W. S.. AU - Donachy, J. H.. AU - Landis, D. L.. AU - Brighton, J. A.. AU - Rosenberg, Gerson. AU - Migliore, J. J.. AU - Prophet, G. A.. AU - White, W. J.. AU - Waldhausen, J. A.. PY - 1978/1/1. Y1 - 1978/1/1. N2 - An interdisciplinary group has developed a left ventricular assist pump system composed of a modified sac type pump, a pneumatic power unit, and a synchronizer. The pump fills from the left ventricle and discharges into the aorta. The system was employed for left ventricular assistance in a series of 12 normal calves, with an average pumping period of 70 +/- 8 days. The system was then evaluated in a series of calves in whom profound left ventricular failure had been produced. These studies indicate that the assist pump is effective in supporting the circulation and completely unloading the left ventricle. The assist system has now been employed in four patients who could not be weaned from ...
Prof. Stephan Schueler is a past president of ISHLT and of the ESCVS. He helped to set up both the Berlin Heart Centre, and a new centre in Dresden before moving to the Freeman Hospital, where he leads the Ventricular Assist Device Programme, which is the subject of this interview. Also shown are his implantation technique and an interview with one of his patients ...
An institutional registry of ECMO patients was surveyed to determine predictors of survival among patients receiving ECMO in the presence of sepsis. Among 151 studied patients, pneumonia was the most common cause of sepsis. Mortality was predicted by advanced age, longer door-to ECMO times, gram-negative sepsis, and sepsis due to infections other ...
Lassistance circulatoire en attente de transplantation. Le bilan des 30 dernières années [Circulatory assistance while waiting for heart transplantation. A report on the last 30 years]
A device to be inserted in a blood vessel in order to aid the pumping of blood in only one direction within that vessel which comprises a gas inflatable and deflatable chamber mounted on support means and divided into an occluding section and a pumping section in direct communication with each other, such that it is necessary to deliver gas directly only to the occluding section, thereby enabling the occluding and pumping sections to be mounted on the support means in any order which further enables the device to be inserted from either above or below the vessel and which also permits thinner and therefore more easily insertable support means when the sections are mounted for insertion from below.
CHD and non-CHD patients had similar levels of clinical support required at transplantation. Within the reoperation group, CHD patients were much less likely to have mechanical circulatory assistance at transplantation, likely representing both underutilization of and fewer appropriate candidates for MCS.. In the population examined by Patel et al, 21 CHD patients were more likely to have a higher PVR (,4 Wood units); in this more contemporary population, we did not find a similar difference. We also did not find a statistically significant impact of elevated PVR on posttransplantation outcomes. PVR is a problematic variable in CHD transplantation patients, many of whom have single-ventricle physiology.20 Neither the United Network for Organ Sharing database nor most single-institution studies18,22 have information about the catheter locations used to measure pretransplantation and posttransplantation pulmonary pressures or about the presence of aortopulmonary collaterals. Further work is needed ...
If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patients written consent to publication and send them to the editorial office before submitting your response [Patient consent forms] ...
Julian and his mother were initially introduced by a social worker to the Childrens Organ Transplant Society when they moved back to British Columbia. Julians transplant experience has been an intense medical journey. At just one-month-old, he was put on the Berlin Heart-a ventricular assistance device that provides mechanically operates the heart. Only two months later, Julian received his heart transplant. While the procedure itself went smoothly, post-op complications included a stroke and seizures. Julians mother, Jeannine, endured setbacks as she could not go back to work and had to quit going to university. She tried to get Julian into child care, but it was extremely difficult to find a place that would accept him with a liable medical condition. As a result, she had to go on income support, making financial matters an additional stressor in an already emotionally and physically stressful time. However, Jeannine ended up getting a job as an Apprentice and shared some empowering ...
AdjuCor GmbH is a medical device company, which develops novel solutions for cardiac assistance in patients with heart failure. Our activities include the conceptual design of heart assist devices, patenting, engineering layout, construction of prototypes and their functional testing in vitro and in vivo. The company receives its expertise from the combination of experienced engineers, physicists and specialists from cardiac surgery and cardiology.. Heart failure is a disease process of structural or functional changes within the myocardium, which results in the progressive inability of the heart to pump the required amount of blood to the body. AdjuCor develops heart assist devices for personalized medicine. Our technologies allow for a flexible adaption of system configurations to the individual patients disease progression. Patient-specific implants are constructed based on the patients CT images and location of dysfunctional cardiac regions. Our product range covers the patient-specific ...
Need Circulatory Assistance & other medical supplies? Head to Medex Supply and check out the Juzo Varin Dynamic Specialty Compression Pantyhose with Body Part Form Hip A, Size 3 Short
The story takes place in the same official Code Geass history as the anime, but in a different era. The title character, Renya, is a 17-year-old boy with a mechanical left arm and shuriken throwing stars as his weapons of choice. The story begins when Renya encounters a mysterious, perpetually young witch named Reifū C.C. C.C. has appeared in Japans historical Edo era to seek a new partner for a covenant. Meanwhile, a mysterious man, with a striking resemblance to the character Lelouch of the original anime, also appears with unknown intentions ...
NEW YORK - Surgeons at NewYork-Presbyterian Hospital/Columbia University Medical Center performed the first Total Artificial Heart implant in the New York City area to replace a patients dying heart.. For patients who will die without a heart transplant, the Total Artificial Heart helps them survive until they can get one. By replacing the heart, we are eliminating the symptoms and the source of heart failure, said lead surgeon Dr. Yoshifumi Naka, director of Cardiac Transplantation and Mechanical Circulatory Support Programs at NewYork-Presbyterian/Columbia and associate professor of surgery at Columbia University College of Physicians and Surgeons.. Similar to a heart transplant, the SynCardia temporary Total Artificial Heart replaces both failing heart ventricles and all four heart valves. Once implanted, the Total Artificial Heart provides immediate blood flow of up to 9.5 liters per minute. This high volume of blood flow helps speed the recovery of vital organs, including the brain, ...
TY - JOUR. T1 - Model of right ventricular failure after global myocardial ischemia and mechanical left ventricular support. AU - Shuman, Todd A.. AU - Palazzo, Robert S.. AU - Jaquiss, Robert B.D.. AU - Harper, Baron D.. AU - Barzilai, Benico. AU - Cox, James Lewis. AU - Kouchoukos, Nicholas T.. AU - Wareing, Thomas H.. PY - 1991/7/1. Y1 - 1991/7/1. N2 - Postcardiotomy right ventricular (RV) failure after institution of mechanical left ventricular (LV) support is poorly understood. Using a canine model supported by cardiopulmonary bypass (CPB), the animals underwent 30 min of aortic clamping or no ischemia and were weaned to an LV assist device (LVAD). Echocardiographic measurements of LV and RV cavity size off support allowed calculation of percentage change in cavity area (fractional shortening). There were no differences at baseline. After 2 hrs on LVAD, there were significant differences between ischemic and control groups in both LV (38 ± 12 vs. 61 ± 6) and RV (15 ± 3 vs. 55 ± 12). The ...
An inventor from Turkey presented at the International Exhibition of Inventions of Geneva 2014 the invention: Permanent Total Artificial Heart.. This invention is about permanent total heart device which has been developed for patients who have end-stage heart failure and who are considered for heart transplantation. Via a surgical operation, the device is placed whether completely inside the ventricles of the patients heart or it is placed to the convenient space obtained through removing part of the ventricles. The specially designed motor requires quite a little energy and works simultaneously with ECG signals assuring pulsatile blood flow.. It is often difficult to find suitable heart donors for patients with en-stage heart failure. Therefore, the development of total artificial heart devices is often the only choice. With the development of these devices, it seems that the heart transplantation will not be needed and instead bionic hearts will be used.. The invented artificial heart ...
TUCSON, Ariz., Oct. 4, 2012/ PRNewswire/-- SynCardia Systems, Inc., manufacturer of the worlds first and only FDA, Health Canada and CE approved Total Artificial Heart, announced today that University Medical Center Ljubljana has transplanted Slovenia s first patient to receive the SynCardia temporary Total Artificial Heart.
What Are VADs? Left Ventricular Assist Devices, or known more commonly as LVADs or simply VADs, are designed to take over the function of the weakened hearts left ventricle, which delivers oxygenated blood from the heart to the body. The device, which is implanted in the patients chest, consists of an electric motor and a driveline. A tube placed in the left ventricle diverts blood from the heart to the VAD pump. The pump then propels the blood back into the aorta and out to the rest of the body. This is also known as mechanical circulatory support.
TY - JOUR. T1 - Total artificial heart. T2 - From bridge to transplantation to permanent use. AU - Pierce, William S.. AU - Sapirstein, John S.. AU - Pae, Walter E.. PY - 1996/1. Y1 - 1996/1. N2 - Background. Pneumatic artificial hearts have played an important role in supporting the circulation in patients before cardiac transplantation. Pneumatic hearts have also been used for permanent cardiac replacement, but most agree they have serious limitations. Methods. Several groups are now developing electric artificial hearts in which electrical energy crosses the skin using a wireless technique. The electrical energy powers a small direct-current motor, which actuates the blood pump. Results. Important progress in these devices has resulted in animal survival with electric hearts of more than 1 year. Conclusions. Extensive bench testing and animal testing will be performed before the initial clinical use of these devices will be initiated. One of the early scientific achievements of the 21st ...
Cardiothoracic surgeons at WMCHealth Physicians offer mechanical circulatory support - both temporary and long-term, implantable pumps. Learn more.,
The significance of the utilization of mechanical circulatory support following a myocardial infarction is not well defined. We present a systematic review of this treatment alternative and suggest guidelines to be considered in the treatment of thes
BACKGROUND: Historically, the temporary or short-term ventricular assist device (VAD) was used only as a quick bridge to recovery for children with an acute process. In the current era, the devices that were originally used for temporary support are now being used to support children for longer durations and for a variety of indications. In this study we aimed to describe the overall use, patients characteristics and outcomes of temporary VAD use in children. METHODS: The Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS) is a National Institutes of Health-supported national registry for United States Food and Drug Administration-approved VADs in patients ,19 years of age at the time of VAD implantation (either durable or temporary VAD ...
The 10th International Conference on Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion will be held at the Hall of Flags, University of Pennsylvania, Philadelphia, PA, USA, May 28-31, 2014. Preliminary scientific program is attached for your review.. All abstracts must be submitted online via the conference web site. Please use the same link for conference registration, hotel room and exhibitor registration.. The scientific program of the 10th event has special additional features such as Pediatric CPB-ECLS-MCS Wet-labs, Simulations, Hospital Tours & Case presentations for all pre-registered participants. Important Dates (2013-2014). DATE EVENTS. December 16, 2013 Conference & Hotel Registration Begins. December 16, 2013 Abstract Submission Begins ? Online Only. March 1, 2014 Exhibitor Booth Registration Deadline. March 1, 2014 Final Day for Abstract Submissions. March 7, 2014 Notification of Accepted ...
Mechanical Circulatory Support Therapy In Advanced Heart Failure von Deng Mario C & Naka Yoshifumi und Buchbewertungen gibt es auf Bücher können hier direkt online erworben werden.
Purpose of Review To outline key elements in providing compassionate end-of-life care for pediatric patients with end-stage heart failure on mechanical circulatory support (MCS) such as extracorporeal...
Health, ...BOSTON MA April 9 2008 New devices and research for mechanical cir...The use of mechanical circulatory support devices (MCSDs) is shown to ...Acknowledging this vacancy the NHLBI Pediatric Circulatory Support Pr...The field of pediatric mechanical circulatory support received a boost...,New,research,for,mechanical,support,devices,in,pediatrics,to,be,released,at,ISHLT,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
[134 Pages Report] Check for Discount on Global Intra-aortic Balloon Pump (IABP) Market Status and Future Forecast 2015-2025 report by 99Strategy. Summary The Intra-aortic balloon pump (IABP) is a mechanical...
An intra-aortic balloon pump includes a balloon, a catheter having a relatively small diameter lumen and an extender having a relatively large diameter lumen connected in series. A valve is positioned in the extender adjacent the end of the extender connected to the catheter. The valve enables the extender to be pressurized with a working gas prior to inflation of the balloon and to be evacuated prior to deflation of the balloon. A second valve adjacent the opposite end of the extender permits the intra-aortic balloon pump to commence a pre-inflation step or a pre-deflation step without affecting the pressure in the extender. Separate positive pressure and negative pressure extenders may be provided to reduce the movement of the working gas during inflation and deflation cycles, thereby increasing pneumatic efficiency.
Professor of Surgery (212) 305-0828 Yoshifumi Naka, MD, PhD, is an internationally known heart transplant surgeon and a pioneer in mechanical assist therapy for heart failure. Under his leadership, Columbia University Medical Centers Cardiac Transplantation and Mechanical Circulatory Support Programs have earned international recognition for their contributions in developing and testing new cardiac devices and in training cardiothoracic surgeons around the world. Columbias heart transplant program is the largest U.S. heart transplant program by volume. Dr. Nakas clinical specialties include adult cardiac surgery for coronary artery disease, valvular heart disease, heart transplantation, and mechanical circulatory support device implantation. His research has focused on cardiac and pulmonary transplantation, organ preservation, surgical treatment of atrial fibrillation, vein graft disease after bypass surgery, and outcomes of clinical mechanical circulatory support device surgery and heart
One of several devices proposed to provide circulatory assistance to victims of cardiogenic shock is the intra-aortic balloon pumping technique which utilizes a polyurethane balloon that is inserted through a femoral artery and advanced to a predetermined position in the descending aorta. The balloon is pneumatically driven and typically controlled so as to raise systemic pressure immediately after left ventricular ejection and aortic valve closure. The pressure remains elevated throughout diastole and is lowered via balloon deflation prior to the succeeding ventricular ejection. This form of ventricular assist device has as its goals (1) reduction of the work required of the failing myocardium via reduction of pressure load on the left ventricle and (2) partial replacement of the circulatory role played by the heart by increased mean central aortic pressure and effective cardiac output. As a result, blood flow to the coronary and cerebral circulations is enhanced and increased oxygen supply to ...
Patient being kept alive with Total Artificial Heart receives donor heart transplant at Baylor University Medical Center at Dallas
TUCSON, Ariz., July 31, 2014 (GLOBE NEWSWIRE) -- For the first time, cardiac surgeons, medical professionals and the public can watch the implantation of the SynCardia temporary Total Artificial Heart in a peer reviewed case report paper and matching video posted on the Journal of Visualized Experiments website.
A growing number of people with failing hearts are being given total artificial hearts as they wait for donor hearts to become available. To implant…
Cardiovascular disease is the major cause of mortality and morbidity in the industrialized world. Although death rates from coronary heart disease have been declining, heart failure, which is usually the consequence of obstruction of the coronary arteries, is on the increase. Heart failure is a progressive, debilitating condition that accounts for a high proportion of hospital admissions and readmissions. For some years the only surgical option for treating heart failure has been cardiac transplantation. Unfortunately fewer donor hearts are becoming available, and the number of transplantation operations performed has therefore been falling year by year, despite rising demand. Many patients cannot meet the strict age and other criteria for transplant surgery. Of those who are placed on the waiting list, 25-30% die before a suitable donor is found. Even for those who receive the operation, transplantation may not be a perfect solution. Transplanted hearts often fail through rejection or ...
Did you believe the Jarvik-7 heart would work? I absolutely believed that the implantation was going to work; otherwise I would not have done it. I was confident in the device, and I knew that if I were in Barneys shoes, Id have done it. As a matter of fact, the original Utah Artificial Heart [Jarvik-7] is almost exactly the same as the Total Artificial Heart being used today. I had personally already implanted about 200 artificial hearts in calves and they did really well. Plus, we had a strong team at the University of Utah.. How was success defined? According to the Utah IRB [Institutional Review Board], success was defined as Clark coming out of surgery alive. That shocked me. My idea of success was to give Barney some quality of life, get him up and moving around, and living a bit longer.. Why Barney Clark? We had spent quite a while looking for the right patient and Barney fit the criteria for the kind of patient we were looking for. He was over 50, had chronic heart disease, and had no ...
Worlds Smallest Artificial Heart The worlds smallest artificial heart, made by Italian scientists. This tiny titanium pump was implanted in a baby, at the Bambino Gesu Hospital in Rome May 24, 2012. Doctors from Romes Bambino Gesu Hospital saved the life of the 16-month-old baby with this Artificial heart.
An Active Member shall be any perfusionist active in the practice of extracorporeal circulation technology. There are also opportunities to become a Transitional Active Member for those less than a year removed from graduation from an approved accredited training program. Other options include; an Associate Membership, International Membership, Perioperative Blood Management Clinician Membership, and Student Membership.. Click Here to Learn More ...
The intra-aortic balloon pump, or simply IABP, is a catheterization procedure involving a balloon. The device is inserted into the aorta and is used to increase blood flow to the heart and reduce cardiac output. Although the procedure is sometimes elective, this may not be the case when it comes to a cardiac emergency. The IABP is most often used in individuals suffering from acute heart attack, heart failure and during certain kinds of heart surgery. Risks of having the balloon pump include, but are not limited to, infection, embolism and blockage of other arteries.
Persistence Market Research in its latest study on the global intra-aortic balloon pump market finds that factors such as high risk of infection and potential dangers of artery
Dive into the research topics of Prophylactic value of preincision intra-aortic balloon pump: Analysis of a statewide experience. Together they form a unique fingerprint. ...
This Unit is responsible for the treatment of advanced cardiac decompensation, heart transplant program, and ventricular mechanical support. It optimizes the patients therapeutic management, and makes use of the latest multispecialty strategies.. The Unit is dedicated to patients affected with heart failure who respond poorly to conventional therapy, and become candidates for more complex procedures, such as heart transplantation or ventricular assistance device (VAD, or artificial heart) implantation.. Unstable patients, usually treated in the Intensive Care Unit or Post-Intensive Care Unit are referred to ISMETT by other centers, and treated in this area. The outpatient assessment is an integral part of our program. Comprehensive and continuing management of all the clinical phases is, in fact, a crucial part of a correct diagnosis and treatment of heart disease. In this Unit, a global assessment of all the stages of heart failure takes place (from early stages requiring outpatient assessment ...
Used Abiomed AB5000 Circulatory Support System with Cardiac Pump | Used Abiomed AB5000 Circulatory Support System Low Hours: 164 Unit is in Great Physical Condition Machine powers on fully (due to technicality we were unable to test it) Included in this sale: 1- Used ABIOMED AB5000 Circulatory Support Sys
An inflow conduit assembly for conducting blood from a ventricle to a Ventricular Assistance Device (VAD) is provided. The assembly includes a rigid tube including an angled heart engaging end for insertion into a ventricle. The angled heart engaging end defines a long side for placement adjacent a heart septum. The tube includes an orifice end for attachment to the VAD, and the inflow conduit assembly further includes a coupling for attaching the orifice end of the tube to the VAD. The coupling is movable between a rotatable position wherein the tube is rotatable relative to the VAD, and a locked position wherein the tube is immobile relative to the VAD.
This artificial heart you see here grosses me out, but count me in if it will be able to save lives. Originally invented by a human who is now too feeble to even row a boat, the artificial heart can pride itself in being the first practical robot organ to be incorporated into a living Russian dog. Unfortunately for us humans, our body will most likely reject plastic organs since we arent Barbies to begin with. Thankfully the advances of science has since been able to make us survive much longer than we ought to, and I would love to see more technologically advanced medical discoveries in the near future, with the artificial heart paving the way.. Source: Boing Boing Gadgets. ...
Bevezetés: Magyarországon 2012-ben ünnepelte 20 éves évfordulóját a szívtranszplantáció, ám a mechanikus keringéstámogató eszközök ezalatt az idő alatt a végstádiumú szívelégtelenség korszerű terápiájának hiányzó láncszemét alkották. 2012 májusában, a Semmelweis Egyetem Szív- és Érgyógyászati Klinikáján átadott szívtranszplantációs és szívelégtelenség intenzív osztály, valamint az ehhez társuló eszközfejlesztések tették lehetővé a műszívprogram elindulását. Célkitűzés: A szerzők a program tapasztalatairól számolnak be. Módszer: 2012 májusa és 2014 decembere között 72 beteget 89 esetben kezeltek mechanikus keringéstámogató eszközökkel. A támogatás indikációja valamennyi esetben terápiarefrakter végstádiumú szívelégtelenség, illetve akut bal- vagy jobbszívfél-elégtelenség volt. Eredmények: Huszonhét esetben szívtranszplantáció utáni akut graftelégtelenség, 24 esetben súlyos végstádiumú ...
The concept of mechanical circulatory devices to support functional survival has been validated during the past 40 years of development and is further supported by the INTrEPID trial (3). Before the conclusion of this trial, it became clear from other experience that devices can no longer be tested in this dying population in a simple randomized trial design. However, the major questions remain simple: How long and how well do the patients live?. The answer to how long is currently expressed not by relative reductions of mortality, but in absolute survival with a given device. When survival without devices is negligible, the main component of the equation of net benefit is the survival with devices. A case could be made, particularly with hindsight, that the INTrEPID trial did not need a control group, because the major issue was outcome with the device, not outcome without it. Had 75% of patients survived 1 year, the trial would have been positive. Had 50% of patients survived 1 year, the ...
TY - JOUR. T1 - Fulminant Myocarditis. T2 - Epidemiology, Pathogenesis, Diagnosis, and Management. AU - Sharma, Ajay Nair. AU - Stultz, Jacob Randolph. AU - Bellamkonda, Nikhil. AU - Amsterdam, Ezra Abraham. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Fulminant myocarditis (FM) is a rare, distinct form of myocarditis that has been difficult to classify. Since 1991, the definition of FM has evolved, and it is currently considered an acute illness with hemodynamic derangement and arrhythmias due to a severe inflammatory process requiring support of cardiac pump function and/or urgent management of serious arrhythmias. Diagnosis is aided through use of biomarkers and cardiac imaging, but endocardial biopsy remains the gold standard. Recent evidence has revealed that patients with FM are significantly more likely to die or require heart transplantation than those with the nonfulminant form, refuting previous studies proposing a paradoxically low mortality in patients with FM. Acute hemodynamic derangement is ...
Intra-aortic balloon apparatus is disclosed including a single chamber balloon sealably attached to the end of a catheter for non-surgical insertion into the aorta through the skin as by the standard Seldinger technique. In the preferred embodiment, the extreme end of the balloon is fixedly attached to one end of a separate substantially circumferentially rigid but longitudinally flexible tube open at both ends and disposed within and extending the length of the catheter. The opposite end of the tube remote from the balloon is fixedly attached to means for effecting rotation of the tube within the catheter and thereby result in controlled sequential wrapping and unwrapping of the balloon about the tube. In use, the balloon is pumped in conventional manner via the catheter and access through the tube is provided to the interior of the aorta at the extreme end of the balloon. When the end portion of the tube within the balloon is formed of a relatively flacid or flexible material, it is advantageous to
Tucson, Ariz. (PRWEB) October 08, 2013 -- Kevin Stroh, 25, was fighting for his life against congestive heart failure, the same disease that claimed the life
Artificial Heart:The FDA is asking Symbion Inc for a report on complications experienced by the last three artificial heart recipients at the Humana Hospital in
The Jarvik 2000 heart includes the blood pump inside the natural heart (white arrow), the internal cable (blue arrow), the behind-the-ear connector (green arrow) the belt worn controller (yellow arrow), the belt worn battery (grey arrow), and the external cables (black).. Here we cover the background, basic design elements, and surgical placement of the patented Jarvik 2000 post-auricular cable and connector. Transmission of power into the body has been one of the most difficult problems for developers of mechanical circulatory support devices.. The performance objectives are well defined and include:. ...
The report Titled Intra-aortic Balloon Pump (IABP) conducts a deep evaluation of the current state of Intra-aortic Balloon Pump (IABP). ...
A 40-year-old woman became the world`s first female artificial heart patient Thursday, receiving a smaller version of the Jarvik-7 pump designed for her chest cavity, hospital officials said.Mary
France has begun the first human trial of artificial heart, which aims at overcoming shortages of organs available for transplant.
The second person in France to receive a much-hyped new-generation artificial heart has died eight months after receiving the transplant, biomedical firm Carmat said Tuesday.
The smallest artificial heart in the world, weighing only 11 grams, was enough to save life of an infant boy suffering a deadly disease. Italian doctors who completed the surgery say it kept the baby alive till a donor was found.
Artificial heart Information on IEEEs Technology Navigator. Start your Research Here! Artificial heart-related Conferences, Publications, and Organizations.
Artificial heart technology has been around a while, but this new invention by European scientists is so convincing in its emulation of a real hearts...
Artificial heart patient Anthony Mandia yesterday continued to rebound from Tuesdays setback, when he lapsed in and out of a near-unconscious state for several hours.Dr. John Burnside, spokesman
Its been a bad week for the medgadget industry, beginning with the Guidant defibrillator recall, and now the FDA rejection of AbioMeds artificial heart,
Borges JC, Ramos CH (April 2005). "Protein folding assisted by chaperones". Protein and Peptide Letters. 12 (3): 257-61. doi: ... "Circulation Research. 83 (2): 117-32. doi:10.1161/01.res.83.2.117. PMID 9686751.. ... They play an important role in protein-protein interactions such as folding and assisting in the establishment of proper ... Circulation. 111 (14): 1792-9. doi:10.1161/01.CIR.0000160851.41872.C6. PMID 15809372.. ...
Prolonged Assisted circulation after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of ... A centrifugal artificial heart which alternately pumps the pulmonary circulation and the systemic circulation, causing a pulse ... Mechanical Devices to Assist the Failing Heart: Proceedings. National Academies. 1966.. *^ "Wayback Machine" (PDF). 2008-11-12 ... The first heart assist device was approved by the FDA in 1994, and two more received approval in 1998.[67] While the original ...
Assisted Circulation 2. W. Ertel H. Reichenspurner D. Peters M. Gokel N. Franke W. Land. Springer-Verlag. p. 334. ISBN 978-3- ...
Assisted by W. F. Carter ... private circulation, and issued. pp. 231-232. Ellery, Harrison; Bowditch, Charles Pickering (1879 ...
"Dispatcher-assisted cardiopulmonary resuscitation: risks for patients not in cardiac arrest". Circulation. 121 (1): 91-7. doi ... "Circulation. doi:10.1161/CIRCULATIONAHA.114.014542.. *^ a b Davis, Robert (July 28, 2003). "Special report: Many lives are lost ... "Circulation. 133 (4): e38-e360. doi:10.1161/CIR.0000000000000350.. *^ Go, Alan S.; Mozaffarian, Dariush; Roger, Véronique L.; ... "Circulation. 139 (10): e56-e528. doi:10.1161/CIR.0000000000000659.. *^ Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, ...
Assisted circulation with an auxiliary heart transplant. An experimental study. J Thorac Cardiovasc Surg. 1972 May;63(5):696- ... Circulation. 1996 Oct 15;94(8):1815-7. PMID 8873654 Zerbini EJ. Results of replacement of cardiac valves by homologous dura ...
Water circulation was assisted by an impeller. By the time of the following Motor Show the worm drive at the rear of the engine ...
Prolonged Assisted circulation after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of ... A centrifugal artificial heart which alternately pumps the pulmonary circulation and the systemic circulation, causing a pulse ... While the original assist devices emulated the pulsating heart, newer versions, such as the Heartmate II, developed by The ... An artificial heart is distinct from a ventricular assist device (VAD) designed to support a failing heart. It is also distinct ...
It assists in the circulation of blood and protects and confines the visceral organs. It also provides the main shaping ...
The four boilers have single divided furnaces and assisted circulation. Each has a maximum continuous rating of 1565 t/h ( ... The Executive partner for (ADG) was Rex Savidge and Architect in charge was John Gelsthorpe assisted by Norman Simpson. West ...
His wife assisted by preparing the models for their scene. Collier's couldn't keep up with the rapidly changing times following ... The main culprit was television, which dramatically affected its advertising and circulation revenue. Collier's top competitors ... Referee Paul assisted her off the court. Accessed via Enter: "women's finals reached." The Post-Star, July ... It showed twenty miniature scenes of children worldwide, in their various assisting roles. Martin designed three billboards for ...
They are assisted by Art Directors Alex Barrow and Maggie Li. OKIDO Magazine, an independent publication, was started by ... OKIDO Magazine is published monthly with a circulation of over 9,000. The magazine was funded by a Wellcome Trust Small Arts ...
CSF production and circulation[edit]. Cerebrospinal fluid is circulated through the ventricles, cisterns, and subarachnoid ... There it is called the central ligament and assists with movements of the trunk of the body.[6] ... The pia spans every surface crevice of the brain other than the foramina to allow the circulation of CSF to continue.[9] ... About 150 mL of CSF is always in circulation, constantly being recycled through the daily production of nearly 500 mL of fluid ...
As a young man, Alexander Fraser Pirie assisted at his father's newspaper office. The paper struggled to maintain circulation ... Jane Pirie had actively assisted in her husband's publishing and printing business in Guelph, and in the 1890s had drafted an ... Walpole Murdoch), who had been assisting Pirie since the death of her sister-in-law. Pirie's youngest son, Goldwin McCausland ...
Richenbacher WE and Pierce WS: Chapter 19: Assisted Circulation and the Mechanical Heart. In, Heart Disease. Fifth Edition. Ed ... The Pierce-Donachy Ventricular Assist Device, also known as the Penn State Assist Pump, was designated an International ... The original pneumatic heart assist pump, now known as the Thoratec ventricular assist device (Thoratec Pneumatic VAD), has ... His pioneering work led him to be considered around the world as a father of the ventricular assist device. The group, ...
He served as a reporter, editor and assistant circulation director for the Philadelphia Inquirer from 1983 to 2004. He founded ... The Inquirer's computer-assisted reporting team in 1993. He was assistant managing editor, at The Indianapolis Star from 2004 ...
The kumara was assisted by Mahamatyas and council of ministers. This organizational structure was reflected at the imperial ... Certain gold coins were in circulation as well. The coins were widely used for trade and commerce Historians theorise that the ...
The third-stage larvae are carried by general circulation to the heart and lungs. In the lungs, they enter alveoli and begin to ... The larvae release enzymes to assist their passage through the skin. There are three species that infect humans. Fourth-stage ...
LSD, psilocybin, and MDMA-assisted psychotherapy for conditions such as depression,[18] anxiety, addiction, and post-traumatic ... cerebral circulation, cranial compliance, and their relationship to age-related cognitive decline. ... psychedelic-assisted therapy. Amanda Feilding and the Beckley Foundation are currently trying to secure funding to expand this ... "Implications for psychedelic-assisted psychotherapy: Functional magnetic resonance imaging study with psilocybin". British ...
In practice only boilers with fan assisted fuel/air circulation will have the modulating feature. The fan also mixes gas and ...
The Secretary General of the League, Sir Eric Drummond, was also present, and assisted in the preparation of the agenda and ... The goal was to find a solution to monetary problems and facilitate the circulation of goods and funds. Following the ... In 1921 they helped to assist the approximately 1.5 million people who fled the Russian Revolution of 1917. In April 1920, ... During the following years the League assisted many European countries: Austria, Hungary, Greece, Bulgaria, etc. The Fiscal ...
This larger circulation can assist in bringing in national advertising to weeklies. Weeklies in chains may also have a ... A circulation manager keeps track of subscribers (this can range from only a couple hundred to tens of thousands of subscribers ... The size of the news staff varies, depending on the size of the newspaper and its circulation area. Some papers have a staff of ... Weekly newspapers tend to have smaller circulations than daily newspapers, and often cover smaller territories, such as one or ...
As engine power increased, increased flow was required and so engine-driven pumps were added to assist circulation. More ... so the circulation became entirely dependent on the pump and might even be reversed against the natural circulation. An engine ... This circulation can either be open-loop, as when the substance in a holding tank is passed in one direction via a heated ... Thermosyphon circulation in a simple solar water heater (not a working model; there is no water supply to replenish the tank ...
This, too, assisted the smooth transfer to the new currency. On 2 May 1969, Sir Walter D. Scott wrote to Treasurer William ... It would give rise to higher prices and would probably require the circulation of a half-cent coin. As with the naming of the ... Davey, Stephen; Winning, Susan (24 July 2019). ""Mr Decimal" assisted smooth transfer to the new currency". Sydney Morning ...
Rama was assisted by circulation manager Felipe Tabasa, and editors Julio Pongan and Eustaquio B. Gonzales. By 1922, Nueva ... In its heyday, Bag-ong Kusog was the leading periodical with a circulation of 7,000, considered high at that time. It was the ... Bag-ong Kusog (New Force) was a periodical in Cebuano language that was in circulation before World War II. Established in 1915 ...
Utilization of aquatic organisms like phytoplankton, zooplankton assist in carbondioxide and oxygen circulation. Seaweed ... Currently, many conventional fish farming practices take place in the coastal zones with open circulation. This places an ...
It is the duty of every revolutionist to assist in circulating this book." -Leon Trotsky "Ignazio Silone's Fontamara portrays ... This book deserves a circulation of many million copies. But whatever may be the attitude of the official bureaucracy towards ...
The site was initially created by Philippe Girolami (giro). Anssi Johansson (avij) has been assisting with running the site ... Euro banknotes and coins were put into circulation on 1 January 2002 and EBT has been tracking notes since then. ...
From 1978 to 2004, book circulation per user declined approximately 50%. The growth of audiovisuals circulation, estimated at ... a process that may be assisted through signage, maps, GPS systems, or RFID tagging. ... Circulation (or Access Services) - Handles user accounts and the loaning/returning and shelving of materials.[137] ... Morris, V. & Bullard, J. (2009). Circulation Services. In Encyclopedia of Library and Information Sciences (3rd ed.). ...
These amyloid imaging probes permit the visualization of amyloid plaques in the brains of Alzheimer's patients and could assist ... 2002). "Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography". Circulation. ... Journal of Computer Assisted Tomography. 3 (6): 804-814. doi:10.1097/00004728-197903060-00018. ISSN 0363-8715. PMID 315970.. ... usually into blood circulation). Each tracer atom has been chemically incorporated into a biologically active molecule. There ...
One example of high-risk devices are those with Embedded software such as pacemakers, and which assist in the conduct of ... effect on the central circulation or nervous system, diagnostic impact, or incorporation of a medicinal product. Certified ... but which may be assisted in its function by such means;" ...
Chemically Assisted Nuclear Reactions (CANR),[79] Lattice Assisted Nuclear Reactions (LANR), Condensed Matter Nuclear Science ( ... if fluid circulation within the cell becomes significantly altered.[154][155] Recombination of hydrogen and oxygen within the ...
The Kurdish tribes present in Baluchistan and some of those in Fars are believed to be remnants of those that assisted and ... Most of these blades in circulation stem from the 19th century. Another distinct form of art from Sanandaj is 'Oroosi', a type ...
"Venturi or air circulation?, that's the question". face2fire (in Spanish). Retrieved 2019-07-14.. ... A scuba diving regulator to assist the flow of air once it starts flowing ...
Anything that can assist in bringing this number down is highly recommended and medical simulation has proven to be the key ... The aim is to reduce stress, accelerate normal recovery, and assist in both the cognitive and emotional processing of the ...
A biofuel is a fuel that is produced through contemporary biological processes, such as agriculture and anaerobic digestion, rather than a fuel produced by geological processes such as those involved in the formation of fossil fuels, such as coal and petroleum, from prehistoric biological matter. Biofuels can be derived directly from plants (i.e. energy crops), or indirectly from agricultural, commercial, domestic, and/or industrial wastes.[1] Renewable biofuels generally involve contemporary carbon fixation, such as those that occur in plants or microalgae through the process of photosynthesis. Other renewable biofuels are made through the use or conversion of biomass (referring to recently living organisms, most often referring to plants or plant-derived materials). This biomass can be converted to convenient energy-containing substances in three different ways: thermal conversion, chemical conversion, and biochemical conversion. This biomass conversion can result in fuel in solid, liquid, or ...
Many uninjured fans assisted the injured; several attempted CPR and others tore down advertising hoardings to use as stretchers ... lung or blood circulation function for some time after being removed from the crush. The report stated that placing fans who ... its average circulation in Liverpool was 12,000 copies a day.[254][255] ...
Nightingale was assisted in Paris by her friend Mary Clarke.[19] They were deployed about 295 nautical miles (546 km; 339 mi) ... Nightingale's note was in circulation alongside the images of Sir Isaac Newton, William Shakespeare, Charles Dickens, Michael ... to a wireless computer system it developed to assist nursing.[88] ...
Four prospective American studies". Circulation 79 (1): 8-15. PMID 2642759. *↑ Espenshade PJ, Hughes AL (2007). "Regulation of ... Recently, cholesterol has also been implicated in cell signaling processes, assisting in the formation of lipid rafts in the ... The excretion and reabsorption of bile acids forms the basis of the enterohepatic circulation which is essential for the ... The excretion and reabsorption of bile acids forms the basis of the enterohepatic circulation which is essential for the ...
B cells: releases antibodies and assists activation of T cells. *T cells: *CD4+ Th (T helper) cells: activate and regulate T ... An increase in the number of white blood cells in circulation is called leukocytosis.[14] This increase is most commonly caused ... Neutrophilia is an increase in the absolute neutrophil count in the peripheral circulation. Normal blood values vary by age.[15 ... Increased destruction of cells in peripheral circulation can stimulate bone marrow. This can occur in hemolytic anemia and ...
Aside from assisting in Lavoisier's laboratory research, she was responsible for translating a number of English texts into ... Robert Darnton estimates that there were approximately 25 000 copies of the Encyclopédie in circulation throughout France and ... With the exception of daughters of craftsmen, who sometimes learned their father's profession by assisting in the workshop, ... Caroline Herschel began her astronomical career, although somewhat reluctantly at first, by assisting her brother William ...
with Mary Richardson, assisted by George Propheter. 1901.. CS1 maint: others (link). ... "Strong Circulation: How a weight-lifting and diet fanatic built a publishing empire a century ago". The Wall Street Journal ...
Night-flushing cools the house by increasing ventilation at night, when the outdoor air is cooler;[5] windtowers can assist ... Buoyancy is usually not the main effect driving windcatcher air circulation[2] during the day. ...
150 billion a year by 2020 to assist the world's poorest countries in adapting to climate change.[82] ...
Circulation. 104 (15): 1869-74. doi:10.1161/hc4001.096152. PMID 11591629. These diets are generally associated with higher ... researcher hired to assist with the project, wrote that the carbohydrate-insulin hypothesis had been falsified by experiment.[ ...
... the larynx is also pulled upwards to assist this process. Stimulation of the larynx by ingested matter produces a strong cough ... the liver via the portal venous system for further processing and detoxification before returning to the systemic circulation ...
This is why the World Health Organization (assisted by the National Influenza Centers) makes recommendations for two different ... "Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling ...
On May 5, 2009, Smith was assisting two Navy divers, Bill Dodd and Corey Seymour, who were 300 feet from Aquarius using an ... Systemic circulation. Decompression. theory. *Decompression models: *Bühlmann decompression algorithm. *Haldane's decompression ...
A study called the EMPOWER trial was designed to assess the effectiveness and safety of domperidone in assisting mothers of ... the barrier between the blood circulation of the brain and the rest of the body) so has no effect on the extrapyramidal ...
In the meantime there will be time for the repair of unsafe sea walls, and for the circulation of this notice by means of your ... Can I forget the lives I may in person have assisted to save? Can one ever forget his experiences when, on many occasions, ...
Circulation 2010; 122:S729-S767. *^ a b Daniel Limmer and Michael F. O'Keefe. 2005. Emergency Care 10th ed. Edward T. Dickinson ... A recent advancement in the safety of manual ventilation may be the growing use of time-assist devices that emit an audible and ... Circulation 2004: 109:1960-1965. *^ Lee HM, Cho KH, Choi YH, Yoon SY, Choi YH. Can you deliver accurate tidal volume by manual ...
Airway, Breathing and Circulation[edit]. First aid treats the ABCs as the foundation of good treatment. For this reason, most ... Examples of modern additions include the CPR face shields and specific body-fluid barriers included in modern kits, to assist ...
When red blood cells reach the end of their life due to aging or defects, they are removed from the circulation by the ... This nitric oxide transport to peripheral tissues is hypothesized to assist oxygen transport in tissues, by releasing ... Free hemoglobin is then cleared from the circulation via the hemoglobin transporter CD163, which is exclusively expressed on ... Globulin is metabolised into amino acids that are then released into circulation. ...
... is an anastomosis between a vein of the portal circulation and a vein of the systemic circulation, which allows blood to bypass ... Anastomosis can be performed by hand or with an anastomosis assist device.[5] Studies have been performed comparing various ... "The Use of Enclose®II Anastomosis Assist Device for the Proximal Coronary Branch Anastomosis to Vascular Graft". Annals of ...
In addition about $275 million of coin was in circulation. The new administration policy announced in October would be to make ... The first bill extended the life of the bureau, originally established as a temporary organization charged with assisting ... While the old state bank notes were disappearing from circulation, new national bank notes, backed by species, were expanding. ...
In 2016, Maduro again claimed that the United States was attempting to assist the opposition with a coup attempt. On 12 January ... in a printed media of national circulation the documents that certify the strict compliance with Articles 41 and 227 of the ... with some of their funds possibly assisting Maduro's presidential campaign in the 2013 Venezuelan presidential election and ... "Delegations from 15 countries to assist Maduro's inauguration in Venezuela". Retrieved 18 April 2013. ...
Florence frequently visited nurseries and daycare centers to assist mothers who had to work during the day. Alongside other ... She organized a circulation department, improved distribution, trained the newsboys, and purchased equipment at keen prices. ...
As a result, additional major and minor criteria have been developed to assist in the diagnosis of hepatorenal syndrome.[3] ... Type 2 HRS is thought to be part of a spectrum of illness associated with increased pressures in the portal vein circulation, ... Deteriorating liver function is believed to cause changes in the circulation that supplies the intestines, altering blood flow ... Liver dialysis involves extracorporeal dialysis to remove toxins from the circulation, usually through the addition of a second ...
There are many uses for MEG, including assisting surgeons in localizing a pathology, assisting researchers in determining the ... human circulation balance', which could non-invasively measure the redistribution of blood during emotional and intellectual ...
assisted circulation synonyms, assisted circulation pronunciation, assisted circulation translation, English dictionary ... definition of assisted circulation. n. 1. Movement in a circle or circuit, especially the movement of blood through bodily ... to be in circulation [money] → être en circulation. to be out of circulation, to be withdrawn from circulation [money] → être ... pulmonary circulation - circulation of blood between the heart and the lungs. vitelline circulation - circulation of blood ...
Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person ... Your Name) thought you would like to see the Circulation web site. ... Circulation. 2013;CIRCULATIONAHA.113.005496, originally published August 27, 2013 ... Circulation. 2013;CIRCULATIONAHA.113.005496, originally published August 27, 2013 ...
Heart disease and stroke statistics-2013 update: a report from the American Heart Association. Circulation. 2013;127:e6-e245. ... Thank you for your interest in spreading the word on Circulation.. NOTE: We only request your email address so that the person ... In this issue of Circulation, Lewis and Eisenberg12 report their analysis of dispatch recordings and EMS records from 476 out- ... Dispatcher-assisted cardiopulmonary resuscitation: time to identify cardiac arrest and deliver chest compression instructions. ...
The initial technical and clinical results of Solitaire AB stent-assisted coiling of different types of wide-necked aneurysms ... in the posterior circulation are highly encouraging, and this technique may improve the endovascular treatment of these ... Stent-assisted coil embolization of posterior circulation aneurysms using solitaire ab: preliminary experience Neurosurgery. ... results of Solitaire AB stent-assisted coiling of different types of wide-necked aneurysms in the posterior circulation are ...
An essential contribution to the process of developing right ventricular assist devices (RVADs) is the in vitro test bench, ... a right heart mock circulation loop (MCL) was developed. Incorporating an anatomically shaped silicone RV and a silicone atrium ... Design of a right ventricular mock circulation loop as a test bench for right ventricular assist devices ... Design of a right ventricular mock circulation loop as a test bench for right ventricular assist devices. ...
Dynamic Left Ventricular Assist Device Inflow Obstruction. Edo Y. Birati, James N. Kirkpatrick, J. Eduardo Rame, Rupa Bala, ... Dynamic Left Ventricular Assist Device Inflow Obstruction. Edo Y. Birati, James N. Kirkpatrick, J. Eduardo Rame, Rupa Bala and ... Dynamic Left Ventricular Assist Device Inflow Obstruction. Edo Y. Birati, James N. Kirkpatrick, J. Eduardo Rame, Rupa Bala and ... Your Name) thought you would like to see the Circulation: Heart Failure web site. ...
Outflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device. Juan G. Duero Posada, Yasbanoo Moayedi, Mosaad ... Outflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device. Juan G. Duero Posada, Yasbanoo Moayedi, Mosaad ... Outflow Graft Occlusion of the HeartMate 3 Left Ventricular Assist Device. Juan G. Duero Posada, Yasbanoo Moayedi, Mosaad ... Continuous-flow ventricular assist devices have demonstrated clinical superiority compared with the first-generation pulsatile ...
We constructed SMV uisng both LDMs and evaluated the basic performance of SMV with mock circulation. Stroke work (SW) was ... Publications] Toda K., Nakatani T., et al.: Effect of cardiomyoplasty for right heart assist on right heart failure during ... left ventricular assistance Application of skeletal muscle to heart assist. (in press).. *. Description. 「研究成果報告書概要(欧文)」より ... muscle after preconditioning is one of the important problems in application of skeletal muscle for assited circulation. To ...
... arginine enhances healthy circulation. Also stimulates HGH -Human Growth Hormone - Circulation Formula enhances circulation and ... Circulation Formula - Stimulate Circulation Safely and Successfully Circulation Formula is a premium formula that enhances ... Firm up your circulation with Circulation Formula!. Product Information Sheet. CIRCULATION FORMULA. ... Contains L-Arginine to Support Circulation*. Circulation Formula is a premium scientific formulation that includes the amino ...
... interaction model analysis of cerebrospinal fluid circulation in patients with continuous-flow left ventricular assist devices ... The current 1-dimensional fluid structure interaction model (FSI) for understanding cerebrospinal fluid (CSF) circulation ... requires pulsatility as a precondition and has not been applied to patients with continuous-flow left ventricular assist ...
Assist in Blood Circulation. Effective Formula with Hawthorn Berry, Garlic & More. 60 Capsules. ... Written by Albert Crenshaw Posted in Health Products Tagged with Advanced, Aid., Assist, Berry, Best, Blood, Capsules, ... These ingredients are thought to temporarily relieve symptoms such as stress and slow blood circulation. ... L-Arginine 500mg 250 Caps - Cardiovascular Health Support Formula - L Arginine Enhances Circulation - Lifetime 100% ...
Cardiac Transplantation and Prolonged Assisted Circulation." Harrisons Principles of Internal Medicine, 18e Longo DL, Fauci AS ... Cardiac Transplantation and Prolonged Assisted Circulation. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J ... the option of permanent mechanical assistance of the circulation. In the future, it is possible that genetic modulation of ...
... download Assisted species or analysts as die those exceptions by using such results to ... Where download Assisted Circulation provides in this story is a human ETHYLENE. even, crap participants between the zeros of ... intra-regional download Assisted Circulation 3 1989 growth thank that you was Wratt of . Your efforts on first efficiency ... The seeking download Assisted Circulation 3 of maternal effects of study, alongside cheap formations of government, Spur and ...
A to Z Mens Health Womens Health Senior Health Body System Support Circulatory System and Liver Restorer Circulation Assist ... May increase circulation to the extremities. * Provides essential fatty acids, which benefit heart health.. [Product Details ... Improves overall circulation. • Aids in the regulation of the glandular system. • Provides extra energy. • Helps regulate blood ... Enhances bodily function by improving blood quality and circulation. •Helps strengthen the immune system. •Soothes the nerves ...
... support device recipients in the International Society of Heart and Lung Transplantation Mechanically Assisted Circulation ... presence of biventricular assist device, total artificial heart or right ventricular assist device, and Interagency Registry ... presence of biventricular assist device, total artificial heart or right ventricular assist device, and Interagency Registry ... presence of biventricular assist device, total artificial heart or right ventricular assist device, and Interagency Registry ...
This can be an all-natural and easy way to assist reduces or perhaps takes away the pores and skin issue. Total doc socks for ... Increased circulation of blood implies that the muscle tissue is becoming a lot more oxygenated blood vessels faster. ... Compression socks, also called assist socks, are socks that include strain to the toes and reduce thighs. This could not noise ... Individuals with feet connected medical issues that are caused by lowered circulation of blood utilize the socks to help boost ...
Blood, Heart and Circulation. 02/14/2020 Blood, Heart and Circulation Cocoa could bring sweet relief to walking pain for people ... After robotic-assisted surgery, many patients experience significantly less pain, less blood loss, less scarring, and shorter ... Stony Brook Physician First On LI To Use Minimally Invasive Robotically-Assisted Surgery For ENT Procedures. ...
Blood, Heart and Circulation. 12/13/2017 Heart disease Genomic blood test predicts survival rates after surgery for advanced ... Henry Fords robot-assisted urology program uses a surgeon-controlled robot, the da Vinci minimally invasive surgery system. ... Henry Ford Hospital pioneered the use of robots to assist surgeons in the delicate procedure, and the new study notes that ... Home Surgery and Rehabilitation Long-term study: Robot-assisted prostate surgery is safe ...
Circulation (1). A. J. Lee, P. I. Mowbray, G. D. Lowe, A. Rumley, F. G. Fowkes, and P. L. Allan, "Blood viscosity and elevated ... Blood cell assisted in vivo Particle Image Velocimetry using the confocal laser scanning microscope Sung Min Choi, Wi Han Kim, ... Sung Min Choi, Wi Han Kim, Daniel Côté, Cheol-Woo Park, and Ho Lee, "Blood cell assisted in vivo Particle Image Velocimetry ... We demonstrated the feasibility of blood cell assisted in vivo Particle Image Velocimetry using confocal microscopy. Blood flow ...
Hunt S.A., & Mallidi H.R. Hunt, Sharon A., and Hari R. Mallidi.CARDIAC TRANSPLANTATION AND PROLONGED ASSISTED CIRCULATION. In: ... Hunt S.A., & Mallidi H.R. Hunt, Sharon A., and Hari R. Mallidi. "CARDIAC TRANSPLANTATION AND PROLONGED ASSISTED CIRCULATION." ... Cardiac transplantation and prolonged assisted circulation. Loscalzo J. Loscalzo J(Ed.),Ed. Joseph Loscalzo. Harrisons ... or permanent mechanical assistance of the circulation. In the future, it is possible that genetic modulation of ventricular ...
Ventricular assist devices (VADs) help your heart pump blood from one of the main pumping chambers to the rest of your body or ... Circulation. 2012;126(22):2648-2667. PMID: 23109468 ... VAD; RVAD; LVAD; BVAD; Right ventricular assist device; Left ventricular assist device; Biventricular assist device; Heart pump ... Left ventricular assist system; LVAS; Implantable ventricular assist device; Heart failure - VAD; Cardiomyopathy - VAD ...
Biventricular assist device utilization for patients with morbid congestive heart failure. Circulation. 2005;112:I-65-72.Google ... Prolonged assisted circulation during and after cardiac or aortic surgery: prolonged partial left ventricular bypass by means ... Implantable left ventricular assist devices. N Engl J Med. 1998;339:1522-33.CrossRefPubMedGoogle Scholar ... Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435-43.CrossRefPubMed ...
... recent study aimed to determine the most effective tuina pressure and treatment time for improving peripheral blood circulation ... The study, "Optimization of parameters of Yi Zhi Chan Tuina manipulation promotes peripheral circulation," involved 45 healthy ... Session Time, Finger Pressure Influence Effects of Tuina on Circulation. *June 1, 2016 ... the aim of the study was to determine the most effective pressure and treatment time for improving peripheral blood circulation ...
A left ventricular assist device and method is utilized to relieve the hemodynamic burden on a diseased left ventricle in the ... Implantable heart assist system. WO1999060941A1 *. 26 May 1999. 2 Dec 1999. Circulation, Inc.. Apparatus for providing coronary ... Ventricular-assist method and apparatus. US6428464. 9 Apr 1999. 6 Aug 2002. Orqis Medical Corporation. Implantable heart assist ... Staged implantation of ventricular assist devices. US20070197854 *. 26 Jan 2007. 23 Aug 2007. Circulite, Inc.. Heart assist ...
Circulation. 2009;119(3):e21-e181.. *Lum PS, Burgar CG, Shor PC, et al. Robot-assisted movement training compared with ... Disabil Rehabil Assist Technol. 2018;13(7):704-715.. *Stein J, Bishop L, Gillen G, Helbok R. Robot-assisted exercise for hand ... In a RCT, Hornby et al (2008) examined the effects of robotic-assisted versus therapist-assisted locomotor training (LT). Both ... Esquenazi A, Lee S, Packel AT, Braitman L. A randomized comparative study of manually assisted versus robotic-assisted body ...
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any ... Implantable mechanical system for assisting blood circulation. October, 1995. Liotta. 5449342. Apparatus for assisting blood ... Apparatus for mechanically assisting circulation of the blood in the human body. 1977-07-12. Thoma. ... Cardiac replacement and assist devices. 1977-01-25. Runge. 3995617. Heart assist method and catheter. 1976-12-07. Watkins et al ...
Circulation. BACKGROUND: Dynamic cardiomyoplasty is a relatively new surgical procedure proposed for treatment of severe ... Assisted Circulation. *Cardiac Catheterization. *Cardiomyopathy, Dilated. *Echocardiography, Doppler. *Electric Stimulation ...
Assisted Circulation 3 - 1989 - 621 pages. Atherosclerosis by Christian Weber, Oliver Soehnlein - 2012 - 492 pages. ... Collateral circulation by Daniel Paul Quiring - 1949 - 142 pages. Collateral circulation in clinical surgery by Donald Eugene ... Coronary circulation by Fumihiko Kajiya - 1990 - 336 pages. Coronary Heart Surgery by Helmut Roskamm, Martin Schmuziger - 1979 ...
The purpose of this study was to investigate the possibility of assisting both the systemic and pulmonary circulations using a ... The purpose of this study was to investigate the possibility of assisting both the systemic and pulmonary circulations using a ... The purpose of this study was to investigate the possibility of assisting both the systemic and pulmonary circulations using a ... The purpose of this study was to investigate the possibility of assisting both the systemic and pulmonary circulations using a ...
  • The current 1-dimensional fluid structure interaction model (FSI) for understanding cerebrospinal fluid (CSF) circulation requires pulsatility as a precondition and has not been applied to patients with continuous-flow left ventricular assist devices (CF-LVAD) where pulsatility is chronically reduced. (
  • Patients with end-stage heart failure can now safely undergo durable left ventricular assist device (LVAD) implantation. (
  • The gold standard of treatment for patients with advanced heart failure is heart transplantation, but because of a paucity of donor organs, left ventricular assist device (LVAD) use has increased in recent years. (
  • The Jarvik 2000®, similar to the mechanical pump, is an electrically powered, axial-flow left ventricular assist device (LVAD) designed to enhance the function of the chronically failing heart and, consequently, normalize the cardiac output for a long period of time. (
  • We report the case of 70-year-old man with congestive dilated cardiomyopathy and bioprosthetic mitral valve who underwent surgical implantation of the Jarvik 2000® LVAD, using the miniaturized extracorporeal circulation (MECC) system. (
  • Assist devices may include either a Left Ventricular Assist Device (LVAD) or a Right Ventricular Assist Device (RVAD) or both. (
  • The Left Ventricular Assist Device (LVAD) system was created by Domingo Liotta at Baylor University College of Medicine in Houston in 1962. (
  • Left ventricular assist devices (LVAD) therapy has evolved into a standard therapy for patients with advanced HF [ 9 , 10 , 11 ], not only as a bridge to cardiac transplantation but also as a destination therapy or a bridge to myocardial recovery [ 12 , 13 ]. (
  • Clinical experience has shown that the cardiovascular circulation of patients in severe or total heart failure can be sustained with proper right and left ventricular assist devices (RVAD and LVAD). (
  • Ventricular assist devices (VAD) can be used to support the left ventricle (LVAD), right ventricle (RVAD), or both ventricles (BiVAD). (
  • Left ventricular assist devices (LVAD) are approved for two indications: bridge to transplant (BTT) and destination therapy (DT). (
  • In the last decade, left ventricular assist devices (LVAD) have emerged as the fastest growing form of therapy for stage D HF patients. (
  • Ventricular arrhythmias, which are often lethal in patients with advanced HF, are often well tolerated in patients with LVADs, due to a Fontan-like circulation created by the LVAD. (
  • VADs are designed to assist either the right ventricle (RVAD) or the left ventricle (LVAD), or to assist both ventricles (BiVAD). (
  • citation needed] The first left ventricular assist device (LVAD) system was created by Domingo Liotta at Baylor College of Medicine in Houston in 1962. (
  • The first successful long-term implantation of an LVAD was conducted in 1988 by Dr. William F. Bernhard of Boston Children's Hospital Medical Center and Thermedics, Inc. of Woburn, MA, under a National Institutes of Health (NIH) research contract which developed HeartMate, an electronically controlled assist device. (
  • To evaluate patients with wide-necked aneurysms of the posterior circulation who underwent Solitaire AB (ev3, Inc., Irvine, CA) stent-assisted coil embolization. (
  • The initial technical and clinical results of Solitaire AB stent-assisted coiling of different types of wide-necked aneurysms in the posterior circulation are highly encouraging, and this technique may improve the endovascular treatment of these aneurysms. (
  • Objective To compare the safety and efficacy of stent -assisted and non- stent -assisted coil embolization for the treatment of ruptured anterior circulation aneurysms . (
  • The incidence of perioperative complications , mortality , and clinical outcome at 30 d after coil embolization were compared between the stent -assisted embolization group and the non- stent -assisted embolization group. (
  • There were 47 patients in the stent -assisted embolization group (16 males , aged 56. (
  • 16 years) and 68 in the non- stent -assisted embolization group (27 males , aged 52. (
  • There were no significant differences in the demographic and baseline data between the stent -assisted embolization group and the non- stent -assisted embolization group. (
  • 046 ) in stent -assisted embolization group were significantly higher than those in the non- stent assisted embolization group. (
  • Conclusion Stent -assisted coil embolization for ruptured anterior circulation aneurysms has a high incidence of complications and poor clinical outcomes, and should be avoided as much as possible. (
  • The authors retrospectively reviewed the medical records in a consecutive series of eight patients who underwent planned stent-assisted angioplasty for medically refractory, symptomatic atherosclerotic disease of the intracranial posterior circulation between February 1999 and January 2002. (
  • Staged stent-assisted angioplasty was planned for these patients because the extent and degree of stenosis of the VA and/or basilar artery (BA) lesion portended an excessive procedure-related risk. (
  • Among the patients in whom staged stent-assisted angioplasty was planned, vessel dissection, which necessitated immediate stent placement, occurred during passage of the balloon in one of them. (
  • We conducted this study to evaluate the angiographic results and clinical outcome of patients treated with stent-assisted coiling by using a recently available self-expandable intracranial stent. (
  • A retrospective review of all patients treated with self-expandable stent-assisted coiling between September 2002 and December 2003 was done. (
  • After validation of the technique by experimental studies ( 6 , 7 ) reports of stent-assisted embolization for the treatment of wide-necked aneurysms in human appeared in literature ( 8 - 11 ). (
  • The Solitaire FR is a new self-expanding and fully retrievable nitinol stent based on the Solitaire AB, which is commonly used for stent-assisted treatment of intracranial aneurysms. (
  • Extraaortic counterpulsation using skeletal muscle powered ventricles (SMPVs) has been studied mainly for the purpose of assisting the systemic circulation. (
  • The purpose of this study was to investigate the possibility of assisting both the systemic and pulmonary circulations using a single SMPV. (
  • An SMPV that counterpulses the systemic circulation is placed beside the right atrium (RA) or the right ventricle (RV), the former after procedures such as a Fontan operation, and the latter in cases of biventricular failure. (
  • From these results, it is suggested that the SMPV has enough dilating power to press the RA or to assist the RV while counterpulsing the systemic circulation. (
  • Finally, the patient underwent a left lower lobectomy without the diagnosis of malignancy, based on the possibility of loss of the hook wire into the systemic circulation. (
  • Then, the hook wire proceeded with the blood flow and exited from the lung parenchyma into the systemic circulation via the left atrium. (
  • This is the first report of the rare complication of the hook wire entering the systemic circulation. (
  • To the best of our knowledge, there are no reports on the complication of entry of the hook wire into the systemic circulation. (
  • Herein, we report a case with a missing hook wire, which we concluded had entered the systemic circulation during VATS. (
  • Functionally, LVADs decrease cardiac workload and preload and the neurohormonal response seen in heart failure, and they increase systemic circulation and tissue perfusion. (
  • Pulsatile LVADs mimic the natural rhythmic action of the heart, while continuous-flow LVADs use a motor at fixed speeds, leading to constant ejection of blood to the systemic circulation. (
  • Mechanical circulatory support-either ventricular assist device (VAD, left-sided systemic support) or cavopulmonary assist device (CPAD, right-sided support)-has been suggested as treatment for Fontan failure. (
  • More particularly, the invention relates to a totally implantable circulatory support system which combines the technologies of left ventricular assist pumping for augmenting systemic circulation and skeletal muscle pedicle stimulation for augmenting pulmonary circulation. (
  • From the first implantable ventricular assist device, to the first human heart transplant, the field of mechanical circulatory support has been rapidly evolving. (
  • Implantable left ventricular assist devices. (
  • Implantable electrical left ventricular assist systems: bridge to transplantation and future. (
  • More particularly, this invention is concerned with an electrohydraulic ventricular assist device which integrates several of the major components required for this type of device into one component herein referred to as the Unified System which is implantable into the human thorax. (
  • These small implantable devices are capable of augmenting the circulation to meet the body's physiological needs, both at rest and with exercise, extending survival and improving quality of life (QOL) ( Table 1 ) (5,8) . (
  • Implantable left ventricular assist devices (LVADs) are increasingly being used as a bridge to transplantation or as destination therapy in patients with end stage heart failure refractory to conventional medical therapy. (
  • Cardiac (heart) assist devices differ, in that the patient's heart is not removed during implantation. (
  • As opposed to TAH implantation, the assist device serves to provide only a part of the total cardiac output of the patient's heart. (
  • The Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) has reported the implantation of greater than 4,500 VADs between 2006 and 2011. (
  • The invention is directed to a unified system for an electrohydraulic ventricular assist device adapted for implantation in the thorax and for cannulation to the blood circulatory system comprising an internal electronic controller for generating an actuating signal actuating means far converting the. (
  • Readmissions after continuous flow left ventricular assist devices implantation are common. (
  • According to data from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS), there were a total of 4311 LVADs implanted in participating centers in the United States between June 2006 and September 2011, with a current rate of implantation at 1500 per year ( 6 ). (
  • These socks naturally improve circulation of blood and decrease the bloodstream inside the blood vessels throughout the thighs and legs and feet. (
  • Massage works to elongate the muscles, relieve muscle tightness, restore joint range of motion, and improve circulation. (
  • This invention relates to an extracorporeal circulation device and particularly to an improved mechanical device for temporarily assuming the functions of the heart and lungs in a human being or animal. (
  • To discuss the management of extracorporeal circulation (ECC) for robotically assisted cardiac surgery . (
  • The MECC system obliterated the adverse effects associated with conventional extracorporeal circulation, which are often fatal in critically-ill patients. (
  • This enhanced susceptibility to catastrophic hemodynamic collapse has triggered the development of percutaneous cardiac assist devices such as the intra-aortic balloon pump, Impella (Abiomed Inc., Danvers, Massachusetts), TandemHeart (CardiacAssist, Inc., Pittsburgh, Pennsylvania), and extracorporeal membranous oxygenation to provide adjunctive mechanical circulatory support. (
  • Reduction of the putput power of skeletal muscle after preconditioning is one of the important problems in application of skeletal muscle for assited circulation. (
  • An essential contribution to the process of developing right ventricular assist devices (RVADs) is the in vitro test bench, which simulates the hemodynamic behavior of the native circulatory system. (
  • Independent correlates of non-MCS-related BSI included older age, higher body mass index, previous cardiac surgery, baseline chronic renal disease and dialysis, pre-implant frailty, presence of biventricular assist device, total artificial heart or right ventricular assist device, and Interagency Registry for Mechanically Assisted Circulatory Support category 1. (
  • Ventricular assist devices (VADs) help your heart pump blood from one of the main pumping chambers to the rest of your body or to the other side of the heart. (
  • There are other types of VADs (called percutaneous ventricular assist devices) which can be placed with less invasive techniques to help the left or right ventricle. (
  • First generation ventricular assist devices were pulsatile in nature with a variety of designs and placement and were approved for use as a bridge to transplant and/or post-cardiotomy shock. (
  • A left ventricular assist device and method is utilized to relieve the hemodynamic burden on a diseased left ventricle in the heart of a patient by inserting a shunt having an impellar for effectuating a substantially non-turbulent, non-traumatic flow of blood either from the left atrium or the patient's. (
  • A left ventricular assist device and method is utilized to relieve the hemodynamic burden on a diseased left ventricle in the heart of a patient by inserting a shunt having an impellar for effectuating a substantially non-turbulent, non-traumatic flow of blood either from the left atrium or the patient's venous system, directly into the patient's arterial system. (
  • An artificial heart is distinct from a ventricular assist device (VAD) designed to support a failing heart. (
  • Which Left Ventricular Assist Device Is Best? (
  • Continuous-flow LVADs are further divided into 2 categories: axial flow (HeartMate II Left Ventricular Assist Device from Thoratec Corp) and centrifugal flow HeartMate 3 Left Ventricular Assist System from Abbott Laboratories or HeartWare Ventricular Assist System from HeartWare International. (
  • This paper will describe the evolution and specific program goals of the Artificial Heart Program and provide a description of the left ventricular assist system (LVAS) and total artificial heart (TAH) research efforts. (
  • To study the status of oxidative stress and DNA damage repair in circulating blood leukocytes of heart failure patients supported by continuous flow left ventricular assist devices (LVADs). (
  • Mechanical circulatory support devices including ventricular assist devices (VADs) and total artificial hearts have emerged as an option for the management of end-stage HF. (
  • Initial experiences with the Heartware Ventricular Assist System (HeartWare Inc, Framingham, Massachusetts) centrifugal-flow have been published, and further clinical trials of this device are ongoing. (
  • The remainder of this review will focus on the management of continuous flow left ventricular assist devices (LVADs). (
  • This embodiment suggests new approach for Endovascular Ventricular Assist Device, using the mathematical objective & principle of superposition allow design and calculation of the body response to VAD pump located in the Aorta. (
  • Total artificial hearts (TAH) and ventricular assist devices (VAD) have been valuable clinical tools in recent years with their primary benefit as a bridge to transplantation following acute cardiac failure. (
  • Sarcoidosis-associated hypercalcemia potentiating calcific uremic arteriolopathy in a patient with a left ventricular assist device. (
  • Mehra MR. Magnetically Levitated Left Ventricular Assist Device. (
  • Low Incidence of Pump-Related Infections in Jarvik 2000 Ventricular Assist Device Recipients with a Subcostal Driveline Exit Site. (
  • Leung KM, Kiely MX, Kimbrell A, Asban A, Kelley R, Bleday R, Davids JS, Melnitchouk N. Outcomes of Abdominal Surgery in Patients With Mechanical Ventricular Assist Devices: A Multi-institutional Study. (
  • Ventricular assist devices (VAD) are valuable options for patients with heart failure awaiting cardiac transplantation. (
  • Left ventricular assist devices (LVADs) offer live-saving therapy to transplant-ineligible heart failure patients. (
  • Ventricular assist devices (VADs) are an increasingly common therapy for end-stage heart failure across all ages as a bridge to recovery or transplant and more recently as destination therapy. (
  • Anticoagulant treatment and bleeding complications in patients with left ventricular assist devices. (
  • Authors: den Exter PL, Beeres SLMA, Eikenboom J, Klok FA, Huisman MV Abstract INTRODUCTION: The treatment options for advanced heart failure patients drastically changed with the introduction of left ventricular assist devices (LVADs), either as bridge to transplant or as destination therapy for patients ineligible for transplant. (
  • We compared the frequency and etiology of readmissions between two continuous flow left ventricular assist devices 6 months after implant. (
  • Yu, Sarah N;Takayama, Hiroo;Han, Jiho;Garan, Arthur R;Kurlansky, Paul;Yuzefpolskaya, Melana;Colombo, Paolo C;Naka, Yoshifumi;Takeda, Koji 2018-04-10 00:00:00 Abstract OBJECTIVES Previous studies have shown the usefulness of the subcostal exchange of the HeartMate II left ventricular assist device for device malfunction. (
  • However, 10 (25%) patients had left ventricular assist device-related infections following subcostal exchange that included 7 pump pocket infections and 3 driveline infections. (
  • Ventricular assist device , Subcostal exchange , Device thrombosis , Device infection INTRODUCTION Device malfunction including device thrombosis is a not uncommon and potentially fatal complication during continuous-flow left ventricular assist device (LVAD) support. (
  • Continuous-flow left ventricular assist devices (LVADs) have revolutionized advanced heart failure care. (
  • It is for the larger group of individuals who face a high risk of short-term mortality and little chance of receiving a transplant that the emergence of continuous-flow (CF) left ventricular assist devices (LVADs) holds the greatest promise ( Figure 1 ). (
  • In response to this problem, left ventricular assist devices (LVADs) have now become an accepted bridge to transplant (BTT) or as destination therapy (DT) for patients who are not candidates for heart transplantation ( 4 , 5 ). (
  • A ventricular assist device (VAD) is an electromechanical device for assisting cardiac circulation, which is used either to partially or to completely replace the function of a failing heart. (
  • the right side of the heart is then often able to make use of the heavily increased blood flow), but when the pulmonary arterial resistance is high, then an (additional) right ventricular assist device (RVAD) might be necessary to resolve the problem of cardiac circulation. (
  • He underwent subsequent video-assisted thoracoscopic surgery. (
  • In this article, we report a retrospective, descriptive noncomparative study of the first 25 patients who underwent excimer laser-assisted endovascular lead extraction in our institution. (
  • This invention relates to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR). (
  • Navigational difficulty in the tortuous cerebral circulation is another technical limiting factor for these devices. (
  • Various types of prosthetic devices which may be implanted in patients to provide or assist cardiac function are well known. (
  • To address the need to support the circulation in patients with end-stage HF a wide variety of mechanical circulatory support devices have been developed over the past four decades. (
  • For these and other reasons, a number of mechanical circulatory devices have been designed to replace and/or assist the diseased natural hearts. (
  • Heart-Assist Devices" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (
  • This graph shows the total number of publications written about "Heart-Assist Devices" by people in Harvard Catalyst Profiles by year, and whether "Heart-Assist Devices" was a major or minor topic of these publication. (
  • Below are the most recent publications written about "Heart-Assist Devices" by people in Profiles. (
  • The diversity of criteria adopted by investigators to study the performance of percutaneous circulatory assist devices (PCADs) ( Table 1 , Online Appendix ) would suggest a lack of consensus on what defines high-risk PCI. (
  • In patients with severe biventricular failure who are either in cardiogenic shock or in whom the degree of right ventricular failure is severe and felt to be irreversible (with imminent death), biventricular assist devices can be implanted as a BTT or BTR. (
  • FETAL CIRCULATION Fetal circulation is illustrated, showing right-to-left shunting (dashed arrows) through patent ductus arteriosus (PDA), pulmonary artery (PA) to aorta (Ao), and patent foramen ovale (PFO), right atrium (RA) to left atrium (LA). RV = right ventricle. (
  • The present invention relates to the field of equipment and prothesis as a circulatory device aid for assisting or replacing the right and/or the left ventricle of the natural heart. (
  • LVADs augment the function of a failing heart by providing mechanical circulatory support to restore blood flow and circulation. (
  • One group performed 24 sessions of active-assistive reaching exercise with a simple robotic device, while a 2nd group performed a task-matched amount of un-assisted reaching. (
  • Subjects with an assisted circulation device. (
  • The indications for biventricular assist device (BiVAD) support included: myocarditis (n = 1), cardiomyopathy (n = 8), and one posttransplant heart failure. (
  • Since the initial reports of the abrupt increase in the incidence of device thrombosis with the HeartMate II (HM II, Abbott, Abbott Park, IL, USA) [1, 2], a yearly thrombosis rate of about 10% has been noted by the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) reports [3]. (
  • Methods From January 2014 to September 2018, patients with ruptured anterior circulation aneurysms treated with interventional embolization in Dezhou People ' s Hospital were enrolled retrospectively. (
  • Wide-necked aneurysms are difficult to treat, both surgically and endovascularly, because of their unfavorable geometry, which reduces the possibility of achieving dens packing and elimination of aneurysm from circulation. (
  • To model healthy and diseased arterial-pulmonary hemodynamics in adults (mild and severe PH and RHF), a right heart mock circulation loop (MCL) was developed. (
  • We constructed SMV uisng both LDMs and evaluated the basic performance of SMV with mock circulation. (
  • Computer simulation and mock circulation models of pediatric Fontan patients (15-25 kg) with diastolic, systolic, and combined systolic and diastolic dysfunction were developed. (
  • After robotic-assisted surgery, many patients experience significantly less pain, less blood loss, less scarring, and shorter recovery times, compared to conventional surgery for various conditions. (
  • Co-developed between Medtronic and the recently acquired Mazor Robotics, the Mazor X Stealth Edition seamlessly incorporates Stealth(TM) software technology into the Mazor X(TM) robotic-assisted surgery platform to deliver workflow predictability and flexibility through real-time image guidance, visualization and navigation informed by interactive 3-D planning and information systems. (
  • In all the cases, vacuum -assisted venous drainage (VAVD), continuous blood gas monitoring and ultrafiltration were used during ECC. (
  • The authors concluded that improvements with both forms of exercise confirmed that repeated, task-related voluntary activation of the damaged motor system is a key stimulus to motor recovery following stroke and that robotically assisting in reaching improved arm movement ability, although it did not provide any detectable, additional value beyond the movement practice that occurred concurrently with it. (
  • The establishment of ECC system through peripheral vessels, certain learning curve of perfusion technique and close communication between the surgical team are the key points of ECC for totally robotically assisted cardiac surgery , and VAVD and continuous blood gas monitoring are essential during ECC. (
  • Total support of the circulation of a patient with post-cardiotomy stone-heart syndrome by a partial artificial heart (ALVAD) for 5 days followed by heart and kidney transplantation. (
  • this slightly constricts the blood vessels making the circulation of blood towards the reduced legs and feet gradual. (
  • Increased circulation of blood implies that the muscle tissue is becoming a lot more oxygenated blood vessels faster. (
  • Therapeutic massage can elicit very specific physiological responses, such as, increased blood circulation, increased diameter of blood vessels, and decreased blood pressure. (
  • Nutrients and waste products are exchanged between the blood and the tissues of the body through the circulation. (
  • Promotes circulation to peripheral tissues. (
  • However, this can also translate to shortened, tight muscles, joint range of motion losses, and decreased circulation to compressed tissues. (
  • Better circulation means better delivery of nutrients and oxygen to surrounding cells and tissues. (
  • Prolonged assisted circulation during and after cardiac or aortic surgery: prolonged partial left ventricular bypass by means of intracorporeal circulation. (
  • Prolonged partial left ventricular bypass by means of intracorporeal circulation. (
  • Cardiopulmonary resuscitation ( CPR ) is an emergency procedure that combines chest compressions often with artificial ventilation in an effort to manually preserve intact brain function until further measures are taken to restore spontaneous blood circulation and breathing in a person who is in cardiac arrest . (
  • The result of the VAD is a circuit that receives blood from the heart and pumps it into an arterial circulation. (
  • The findings, published online this month by the journal European Urology, follow an earlier Henry Ford study that found nearly 87 percent of patients whose cancerous prostates were removed by robot-assisted surgery had no recurrence of the disease after five years. (
  • Serial quantitative intravascular ultrasound and computer-assisted grayscale value analysis for plaque composition over four years were obtained in 23 event-free patients treated with sirolimus-eluting stents. (
  • Methods Serial quantitative intravascular ultrasound and computer-assisted grayscale value analysis over four years were performed in 23 event-free patients treated with sirolimus-eluting stents. (
  • A computer-assisted microvessel analysis system was developed to evaluate correlations between the architecture of biopsy specimen microvessels and the outcome for patients with esophageal cancer treated with chemoradiotherapy. (
  • Computer-assisted tumor microvessel analysis is a powerful tool in predicting the outcome for patients with esophageal cancer treated with chemoradiotherapy because intraobserver and interobserver variability is minimized. (
  • Henry Ford Hospital pioneered the use of robots to assist surgeons in the delicate procedure, and the new study notes that robot-assisted radical prostatectomy (RARP) is now the most common technique in the U.S. for treating localized prostate cancer. (
  • However that study looked at open and laparoscopic prostatectomy, and did not include robot-assisted RP. (
  • Henry Ford's robot-assisted urology program uses a surgeon-controlled robot, the da Vinci minimally invasive surgery system. (
  • The group that performed un-assisted reaching exercise improved the smoothness of their reaching movements more than the robot-assisted group. (
  • The authors stated that the inability to detect any additional value of robot-assisted reaching may have been due to the limited sample size of the study and the specific diagnoses of the participants, or the inclusion of only individuals with chronic stroke. (
  • The use of robot-assisted techniques in the performance of surgery has been one of the most important developments in surgery in recent decades. (
  • The US FDA approved the robot-assisted surgical system for gynecological conditions in 2005, and currently gynecological together with urological are the most common surgical procedures performed with the Da Vinci ® robot. (
  • However, robot-assisted surgery presents new challenges for anesthesiologists including patient positioning, as well as adverse effects on pulmonary, cardiovascular and neurological systems. (
  • The current chapter highlights the most important anesthesia related issues during robot-assisted surgery during the preoperative, intraoperative and post-operative phases. (
  • Current status of robot-assisted surgery. (
  • Feasibility and surgical outcomes of conventional and robot-assisted laparoscopy for early-stage ovarian cancer: a retrospective, multicenter analysis. (
  • Current therapeutic options are limited to cardiac transplantation (with the option of mechanical cardiac assistance as a "bridge" to transplantation) or (at least in theory) the option of permanent mechanical assistance of the circulation. (
  • Numerous clinical studies have now confirmed that supplementing the diet with L-arginine, as contained in Circulation Formula, leads to healthy levels of NO in the body. (
  • These findings may be useful to guide clinical cavopulmonary assist strategies in failing Fontan circulations. (
  • The study, " Optimization of parameters of Yi Zhi Chan Tuina manipulation promotes peripheral circulation ," involved 45 healthy male volunteers ages 18 to 40, with a mean age of around 26 years. (
  • Liotta D, Hall CW, Henly WS, Beall AC, Cooley DA, De Bakey M (1963) Prolonged assisted circulation during and after cardiac or aortic surgery. (
  • Liotta D, Hall CW, Henly WS, Cooley DA, Crawford ES, De Bakey ME (1963) Prolonged assisted circulation after cardiac or aortic surgery. (
  • The computerized system translates these electrical signals into the desired motion and then responds in real time with a power boost from the device's motorized elbow brace to assist the desired motion. (
  • Our work exhibits the importance and viability of a self-improving and user adapting computer-assisted EEG analysis system for diagnosing epilepsy which processes each channel exclusive to each other, along with the performance comparison of different machine learning techniques in the suggested system. (
  • All factors including tumor hotspot MVD counts were analyzed using a computer-assisted image analysis system, with the aim of minimizing intraobserver and interobserver variation in microvessel counting and analysis. (
  • Among healthy volunteers, a 10-minute session of Yi Zhi Chan Tuina therapy yielded significantly greater improvements in peripheral blood circulation than a two-minute session, and the use of medium and heavy pressure in these sessions had a significantly greater effect than the use of light pressure, according to recent research. (
  • According to the researchers, the aim of the study was to determine the most effective pressure and treatment time for improving peripheral blood circulation. (
  • In conclusion, manipulation force and treatment time directly influence the effects of Yi Zhi Chan Tuina manipulation in improving peripheral blood circulation," stated the authors. (
  • Learning curve and surgical outcome for robotic-assisted hysterectomy with lymphadenectomy: case-matched controlled comparison with laparoscopy and laparotomy for treatment of endometrial cancer. (
  • 8 - 11 Until now, little has been known about how frequently these and other factors affect cardiac arrest recognition or provision of dispatcher-assisted chest compression instructions by 9-1-1 dispatchers. (
  • In this issue of Circulation , Lewis and Eisenberg 12 report their analysis of dispatch recordings and EMS records from 476 out-of-hospital cardiac arrest cases in King County, Washington, during 2011. (