Aspergillus nidulans
Aspergillus
Aspergillus fumigatus
Aspergillus flavus
Sterigmatocystin
Gene Expression Regulation, Fungal
Hyphae
Benomyl
Reproduction, Asexual
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Amino Acid Sequence
Mutation
Aflatoxins
Furano-furano-benzopyrans that are produced by ASPERGILLUS from STERIGMATOCYSTIN. They are structurally related to COUMARINS and easily oxidized to an epoxide form to become ALKYLATING AGENTS. Members of the group include AFLATOXIN B1; aflatoxin B2, aflatoxin G1, aflatoxin G2; AFLATOXIN M1; and aflatoxin M2.
Transformation, Genetic
Cloning, Molecular
Penicillium
Antifungal Agents
Base Sequence
Sequence Homology, Amino Acid
Gene Deletion
Aspergillus oryzae
Aspergillus ochraceus
Genetic Complementation Test
Fungi
A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.
Mitosis
Diploidy
Acetate-CoA Ligase
RNA, Fungal
Phenotype
Homogentisate 1,2-Dioxygenase
A mononuclear Fe(II)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the pathway for the catabolism of TYROSINE. Deficiency in the enzyme causes ALKAPTONURIA, an autosomal recessive disorder, characterized by homogentisic aciduria, OCHRONOSIS and ARTHRITIS. This enzyme was formerly characterized as EC 1.13.1.5 and EC 1.99.2.5.
Cell Wall
Suppression, Genetic
Mutation process that restores the wild-type PHENOTYPE in an organism possessing a mutationally altered GENOTYPE. The second "suppressor" mutation may be on a different gene, on the same gene but located at a distance from the site of the primary mutation, or in extrachromosomal genes (EXTRACHROMOSOMAL INHERITANCE).
Multigene Family
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Haploidy
Sequence Alignment
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Pulmonary Aspergillosis
Infections of the respiratory tract with fungi of the genus ASPERGILLUS. Infections may result in allergic reaction (ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS), colonization in pulmonary cavities as fungus balls (MYCETOMA), or lead to invasion of the lung parenchyma (INVASIVE PULMONARY ASPERGILLOSIS).
Hydro-Lyases
Drug Resistance, Fungal
Penicillins
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
Enzyme Repression
Gliotoxin
Aspergillosis, Allergic Bronchopulmonary
Genes, Regulator
Chromosomes, Fungal
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Oxidoreductases
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
Expression of atrC - encoding a novel member of the ATP binding cassette transporter family in Aspergillus nidulans - is sensitive to cycloheximide. (1/1128)
A new member of the ABC superfamily of transmembrane proteins in Aspergillus nidulans has been cloned and characterized. The topology of conserved motifs subgroups AtrC in the P-glycoprotein cluster of ABC permeases, the members of this subfamily, are known to participate in multidrug resistance (MDR) in diverse organisms. Alignment results display significant amino acid similarity to AfuMDR1 and AflMDR1 from Aspergillus fumigatus and flavus, respectively. Northern analysis reveals that atrC mRNA levels are 10-fold increased in response to cycloheximide. Evidence for the existence of eight additional hitherto unpublished ABC transporter proteins in A. nidulans is provided. (+info)Insertion analysis of putative functional elements in the promoter region of the Aspergillus oryzae Taka-amylase A gene (amyB) using a heterologous Aspergillus nidulans amdS-lacZ fusion gene system. (2/1128)
Expression of the Taka-amylase A gene (amyB) of Aspergillus oryzae is induced by starch or maltose. The A. oryzae amyB gene promoter contains three highly conserved sequences, designated Regions I, II, and III, compared with promoter regions of the A. oryzae glaA encoding glucoamylase and the agdA encoding alpha-glucosidase. To identify the function of these sequences within the amyB promoter, various fragments containing conserved sequences in the amyB promoter were introduced into the upstream region of the heterologous A. nidulans amdS gene (encoding acetamidase) fused to the Escherichia coli lacZ gene as a reporter. Introduction of the sequence between -290 to -233 (the number indicates the distance in base pairs from the translation initiation point (+1)) containing Region III significantly increased the expression of the lacZ reporter gene in the presence of maltose. The sequence between -377 to -290 containing Region I also increased the lacZ activity, but its maltose inducibility was less than that of Region III. The sequence between -233 to -181 containing Region II had no effect on the expression. These results indicated that Region III is most likely involved in the maltose induction of the amyB gene expression. (+info)The GATA factor AreA is essential for chromatin remodelling in a eukaryotic bidirectional promoter. (3/1128)
The linked niiA and niaD genes of Aspergillus nidulans are transcribed divergently. The expression of these genes is subject to a dual control system. They are induced by nitrate and repressed by ammonium. AreA mediates derepression in the absence of ammonium and NirA supposedly mediates nitrate induction. Out of 10 GATA sites, a central cluster (sites 5-8) is responsible for approximately 80% of the transcriptional activity of the promoter on both genes. We show occupancy in vivo of site 5 by the AreA protein, even under conditions of repression. Sites 5-8 are situated in a pre-set nucleosome-free region. Under conditions of expression, a drastic nucleosomal rearrangement takes place and the positioning of at least five nucleosomes flanking the central region is lost. Remodelling is strictly dependent on the presence of an active areA gene product, and independent from the NirA-specific and essential transcription factor. Thus, nucleosome remodelling is independent from the transcriptional activation of the niiA-niaD promoter. The results presented cast doubts on the role of NirA as the unique transducer of the nitrate induction signal. We demonstrate, for the first time in vivo, that a GATA factor is involved directly in chromatin remodelling. (+info)Unique DNA binding specificity of the binuclear zinc AlcR activator of the ethanol utilization pathway in Aspergillus nidulans. (4/1128)
AlcR is the transcriptional activator in Aspergillus nidulans, necessary for the induction of the alc gene cluster. It belongs to the Zn2Cys6 zinc cluster protein family, but contains some striking differences compared with other proteins of this group. In this report, we show that no dimerization element is present in the entire AlcR protein which occurs in solution as a monomer and binds also to its cognate sites as a monomer. Another important feature of AlcR is its unique specificity for single sites occurring naturally as inverted or direct repeats and sharing a common motif, 5'-(T/A)GCGG-3'. Like most other Zn2Cys6 proteins, AlcR contacts directly with the CGG triplet and, in addition, the upstream adjacent guanine is required for high affinity binding. We also establish that the flanking regions outside the core play an essential role in tight binding. From our in vitro analysis, we propose an optimal AlcR-binding site which is 5'-PuNGCGG-AT rich 3'. (+info)nimO, an Aspergillus gene related to budding yeast Dbf4, is required for DNA synthesis and mitotic checkpoint control. (5/1128)
The nimO predicted protein of Aspergillus nidulans is related structurally and functionally to Dbf4p, the regulatory subunit of Cdc7p kinase in budding yeast. nimOp and Dbf4p are most similar in their C-termini, which contain a PEST motif and a novel, short-looped Cys2-His2 zinc finger-like motif. DNA labelling and reciprocal shift assays using ts-lethal nimO18 mutants showed that nimO is required for initiation of DNA synthesis and for efficient progression through S phase. nimO18 mutants abrogated a cell cycle checkpoint linking S and M phases by segregating their unreplicated chromatin. This checkpoint defect did not interfere with other checkpoints monitoring spindle assembly and DNA damage (dimer lesions), but did prevent activation of a DNA replication checkpoint. The division of unreplicated chromatin was accelerated in cells lacking a component of the anaphase-promoting complex (bimEAPC1), consistent with the involvement of nimO and APC/C in separate checkpoint pathways. A nimO deletion conferred DNA synthesis and checkpoint defects similar to nimO18. Inducible nimO alleles lacking as many as 244 C-terminal amino acids supported hyphal growth, but not asexual development, when overexpressed in a ts-lethal nimO18 strain. However, the truncated alleles could not rescue a nimO deletion, indicating that the C terminus is essential and suggesting some type of interaction among nimO polypeptides. (+info)The abfB gene encoding the major alpha-L-arabinofuranosidase of Aspergillus nidulans: nucleotide sequence, regulation and construction of a disrupted strain. (6/1128)
Using a DNA fragment containing the Aspergillus niger abfB gene as a probe, the homologous Aspergillus nidulans gene, designated abfB, has been cloned from a genomic library containing size-selected HindIII fragments. The nucleotide sequence of the A. nidulans abfB gene shows strong homology with the A. niger abfB, Trichoderma reesei abf-1 and Trichoderma koningii alpha-L-arabinofuranosidase/beta-xylosidase genes. Regulation of abfB expression has been investigated in cultures induced with L-arabitol. The accumulation of abfB mRNA, total alpha-L-arabinofuranosidase activity and AbfB protein levels have been determined in a wild-type A. nidulans strain as well as in different mutant strains. These strains are affected either in their response to ambient pH (paIA1 and pacC(c)14 mutants), carbon catabolite repression (creA(d)4 mutant), the ability to utilize L-arabitol as a carbon source (araA1 mutant) or a combination of both latter genotypes (araA1 creA(d)4). The results obtained indicate that the expression of the A. nidulans abfB gene was higher at acidic pHs and was superinduced in this double mutant. Furthermore, disruption of the abfB gene demonstrated that in A. nidulans AbfB is the major p-nitrophenyl alpha-L-arabinofuranoside-hydrolysing activity but at least one minor activity is expressed, which is involved in the release of L-arabinose from polysaccharides. (+info)Zinc-regulated biosynthesis of immunodominant antigens from Aspergillus spp. (7/1128)
ASPND1 and ASPF2 are immunodominant antigens from Aspergillus nidulans and A. fumigatus, respectively, that are readily synthesized in infections in the human host, as demonstrated by their reactivity with more than 80% of sera from patients with aspergilloma or allergic bronchopulmonary aspergillosis. We demonstrate here that both antigens are exclusively produced under situations of low bioavailability of free Zn2+. Addition of micromolar concentrations of Zn2+ to the culture medium strongly stimulated Aspergillus growth but totally inhibited ASPND1 or ASPF2 production. This effect was specific, since other divalent metals had no effect. Removal of endogenous Zn2+ by a chelator also stimulated ASPND1 production, and the effect was specifically reversed by Zn2+. These results suggest a possible role of these antigens in the survival of the fungus in the lungs. (+info)Disruption of phacA, an Aspergillus nidulans gene encoding a novel cytochrome P450 monooxygenase catalyzing phenylacetate 2-hydroxylation, results in penicillin overproduction. (8/1128)
Aspergillus nidulans utilizes phenylacetate as a carbon source via homogentisate, which is degraded to fumarate and acetoacetate. Mutational evidence strongly suggested that phenylacetate is converted to homogentisate through two sequential hydroxylating reactions in positions 2 and 5 of the aromatic ring. Using cDNA substraction techniques, we have characterized a gene, denoted phacA, whose transcription is strongly induced by phenylacetate and which putatively encodes a cytochrome P450 protein. A disrupted phacA strain does not grow on phenylacetate but grows on 2-hydroxy- or 2, 5-dihydroxyphenylacetate. Microsomal extracts of the disrupted strain are deficient in the NADPH-dependent conversion of phenylacetate to 2-hydroxyphenylacetate. We conclude that PhacA catalyzes the ortho-hydroxylation of phenylacetate, the first step of A. nidulans phenylacetate catabolism. The involvement of a P450 enzyme in the ortho-hydroxylation of a monoaromatic compound has no precedent. In addition, PhacA shows substantial sequence divergence with known cytochromes P450 and defines a new family of these enzymes, suggesting that saprophytic fungi may represent a source of novel cytochromes P450. Phenylacetate is a precursor for benzylpenicillin production. phacA disruption increases penicillin production 3-5-fold, indicating that catabolism competes with antibiotic biosynthesis for phenylacetate and strongly suggesting strategies for Penicillium chrysogenum strain improvement by reverse genetics. (+info)
Protein production and secretion in an Aspergillus nidulans mutant impaired in glycosylation. - Acta Biochimica Polonica -...
Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation<...
Protein kinase C (PkcA) of Aspergillus nidulans is involved in penicillin production. - Leibniz Institute for Natural Product...
The tip growth apparatus of Aspergillus nidulans
Aspergillus nidulans - microbewiki
Difference between revisions of Aspergillus nidulans - microbewiki
Nitrate transport and assimilation in Aspergillus nidulans | Aspergillus & Aspergillosis Website
A single amino acid, outside the AlcR zinc binuclear cluster, is ...: Ingenta Connect
The unique histone H2A gene of Aspergillus nidulans contains three introns
The Aspergillus nidulans snt genes are required for the regulation of septum formation and cell cycle checkpoints<...
Phytochrome-dependent light signaling in Aspergillus nidulans
Analysis of ambient pH stress response mediated by iron and copper intake in Schizosaccharomyces pombe<...
Nuclear migration in a nud mutant of Aspergillus nidulans is inhibited in the presence of a quantitatively normal population of...
The Aspergillus nidulans uvsB gene encodes an ATM-related kinase required for multiple facets of the DNA damage response -...
Chemical and Biochemical Engineering News & Events
Genetic requirements for initiating asexual development inAspergillus nidulans | SpringerLink
A Role for NIMA in the Nuclear Localization of Cyclin B in Aspergillus nidulans | JCB
Amide Utilization in Aspergillus nidulans: Evidence for a Third Amidase Enzyme | Microbiology Society
TamA interacts with LeuB, the homologue of Saccharomyces cerevisiae Leu3p, to regulate gdhA expression in Aspergillus nidulans ...
Molecular origin of the Raman signal from Aspergillus nidulans conidia and observation of fluorescence vibrational structure at...
Molecular cloning and expression in Saccharomyces cerevisiae o...
A haploid strain of the aspergillus nidulans carried the, Ask an Expert
Aspergillus Nidulans in the CNS
Aspergillus nidulans (Eidam) Winter ATCC ® 24766™
Isolation of a sexual sporulation hormone from Aspergillus nidulans. | Journal of Bacteriology
In plants the alc gene expression system responds more rapidly following induction with acetaldehyde than with ethanol. -...
Biotransformation of Progesterone by Whole Cells of Filamentous Fungi Aspergillus brasiliensis
Aspergillus nidulans Dis1/XMAP215 Protein AlpA Localizes to Spindle Pole Bodies and Microtubule Plus Ends and Contributes to...
gene clusters
Regulation of Septum Formation by the Bud3-Rho4 GTPase Module in Aspergillus nidulans | Genetics
Media for culture of Aspergillus nidulans (FGSC) | Aspergillus & Aspergillosis Website
Awake Under Anesthesia
Nuclear traffic in fungal hyphae: in vivo study of nuclear migration and positioning in Aspergillus nidulans. - PubMed - NCBI
ICP -Instituto de Catálisis y Petroleoquímica
Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A....
Altmetric - The ATP synthase subunit 9 gene of Aspergillus nidulans: sequence and transcription
RIM101 - pH-response transcription factor pacC/RIM101 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) -...
Nuclear Accumulation of the GATA Factor AreA in Response to Complete Nitrogen Starvation by Regulation of Nuclear Export |...
Aspergillus Resources
Subject: hydrolysis / Subject: 3 selected / Text Availability: Full Text - PubAg Search Results
The PeroxiBase - View Perox
Browsing by Keywords Green fluorescent protein
Aspergillus nidulans hyphae and sexual spores, SEM - Stock Image C032/3077 - Science Photo Library
Aspergillus nidulans hyphae and sexual spores, SEM - Stock Image C032/3079 - Science Photo Library
The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity<...
Thomas Leonard Ph.D. | Faculty | Clark University
Characterization of Purine Hydroxylase I from Aspergillus nidulans | Microbiology Society
Brain Abscesses Due to Aspergillus nidulans Infection During Induction Chemotherapy for Acute Lymphoblastic Leukemia. - Oxford...
The effect of CreA in glucose and xylose catabolism in Aspergillus nidulans - DTU Orbit
Effect of Rapamycin on Aspergillus nidulans Cell Wall Material Properties :: UMBC Electronic Theses and Dissertations
Biosafety Information Centre
Secondary metabolites of Aspergillus nidulans :: University of Southern California Dissertations and Theses
Aspergillus fumigatus and Aspergillosis by Jean-Paul Latgé, William J. Steinbach - Jason Books
Toxins | Free Full-Text | HGT-Finder: A New Tool for Horizontal Gene Transfer Finding and Application to Aspergillus genomes
DSpace at KOASAS: Cytochrome P450 Monooxygenase-Mediated Metabolic Utilization of Benzo[a]Pyrene by Aspergillus Species
Characterization of the Aspergillus nidulans Septin (asp) Gene Family | Genetics
Phylogeny, identification and nomenclature of the genus Aspergillus - Danish National Research Database-Den Danske...
APSA - FETAL
Sexual Spore | Definition of Sexual Spore by Merriam-Webster
Spontaneous Second-site Suppressors of the Filamentation Defect of prr1Delta Mutants Define a Critical Domain of Rim101p in...
S cerevisiae SST2 protein
Summary Report | CureHunter
Extensive domain shuffling in transcription regulators of DNA viruses and implications for the origin of fungal APSES...
Die Auswirkungen von Mangan-Mangel auf Wachstum und Photosynthese bei der Blaualge Anacystis Nidulans | SpringerLink
subject:(Iron Metabolism Genetic aspects) - OATD
Euoidium chrysanthemi - Plant Parasites of Europe
Digimorph - Alca torda (razorbill)
apsa 80
Qute Balance Forskolin Extract - Natural Weight Loss Formula
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Adjusted Net Cash Flow - How is Adjusted Net Cash Flow abbreviated?
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Avhandlingar.se: EDIBLE FILAMENTOUS FUNGI
Asignacion universal
LITIO ESTABILIZADOR DEL ANIMO PDF
Sichtweiten
Mycoremediation
These fungal strains [Aspergillus oryzae FNBR_L35; Fusarium sp. FNBR_B7, FNBR_LK5 and FNBR_B3; Aspergillus nidulans FNBR_LK1; ... The fungus Aspergillus sclerotiorum CBMAI 849 showed the best performance with regard to pyrene (99.7%) and benzo[a]pyrene ( ... Aspergillus niger recorded maximum decolorization of the dye Basic fuchsin (81.85%) followed by Nigrosin (77.47%), Malachite ... A variety of fungi, such as Pleurotus, Aspergillus, Trichoderma has proven to be effective in the removal of lead, cadmium, ...
Gene density
... nidulans/latest_assembly_versions/GCF_000149205.2_ASM14920v2". ftp.ncbi.nih.gov. Retrieved 2020-12-30. "Aspergillus nidulans ( ... "Aspergillus niger (ID 429) - Genome - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-12-14. "Index of /genomes/refseq/fungi/ ... "Index of /genomes/refseq/fungi/Aspergillus_niger/latest_assembly_versions/GCF_000002855.3_ASM285v2". ftp.ncbi.nih.gov. ...
Hülle cell
In Aspergillus nidulans and Aspergillus heterothallicus Hülle cells associate with the cleistothecia, whereas in Aspergillus ... Different species of the genus Aspergillus produce Hülle cells, including Aspergillus nidulans and Aspergillus heterothallicus ... Carvalho, F. (2002). "An investigation of the nuclei of Hülle cells of Aspergillus nidulans". Genetics and Molecular Biology. ... vary in shape between the more elongated such as in Aspergillus ustus and the globose version like in Aspergillus nidulans. ...
Velvet complex
The proteins were first characterized in Aspergillus nidulans. Some proteins in the complex are light-sensitive, including the ... Amare, MG; Keller, NP (May 2014). "Molecular mechanisms of Aspergillus flavus secondary metabolism and development". Fungal ...
Plant-fungus horizontal gene transfer
Aspergillus nidulans produces sterigmatocystin - a precursor to aflatoxins. Aspergillus was found to have horizontally ... Aspergillus to Podospora represents a large metabolic gene transfer which could have contributed to fungal metabolic diversity ... Podospora and Aspergillus show high conservation and microsynteny sterigmatocystin/aflatoxin clusters along with intergenic ... Sterigmatocystin gene transfer has been observed with Podospora anserina and Aspergillus. Horizontal gene transfer in ...
Nucleobase cation symporter-1
They characterized all Fur proteins in Aspergillus nidulans. Homology modelling, substrate docking, molecular dynamics and ...
Fungus
Hynes MJ (1994). "Regulatory circuits of the amdS gene of Aspergillus nidulans". Antonie van Leeuwenhoek. 65 (3): 179-82. doi: ... Other important model fungi are Aspergillus nidulans and the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe, ... Aspergillus oryzae and Aspergillus sojae". Journal of Food Protection. 70 (12): 2916-34. doi:10.4315/0362-028X-70.12.2916. PMID ... Shoyu koji mold (Aspergillus oryzae) is an essential ingredient in brewing Shoyu (soy sauce) and sake, and the preparation of ...
A. Jamie Cuticchia
Chromosome-specific recombinant DNA libraries from the fungus Aspergillus nidulans. Nucleic Acids Res. 1991 Jun 11;19(11):3105- ... it was possible to quickly map the genome of Aspergillus nidulans. This was one of the first genomes physically mapped In ... In vitro reconstruction of the Aspergillus (= Emericella) nidulans genome. Proc. Natl. Acad. Sci. USA 94 (1997), pp. 14564- ...
Propionyl-CoA
In a study concerning Aspergillus nidulans, it was found that with the inhibition of a methylcitrate synthase gene, mcsA, of ... "Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans". Genetics. 168 (2): 785-94. doi: ...
Nuclear pore
In Aspergillus nidulans NPC composition appears to be effected by the mitotic kinase NIMA, possibly by phosphorylating the ... In organisms that undergo a semi-open mitosis such as the filamentous fungus Aspergillus nidulans, 14 out of the 30 ... "Partial Nuclear Pore Complex Disassembly during Closed Mitosis in Aspergillus nidulans". Current Biology. 14 (22): 1973-1984. ...
Echinocandin B
... is a fermentation product of Aspergillus nidulans and the closely related species, A. rugulosus; discovered in ... Echinocandin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus: isolation and structural components ... 1974 in A. nidulans var. echinulatus strain A 32204 in Germany, it was the first of the echinocandin class of antifungals. ...
Triton X-100
Restricting colony expansion in Aspergillus nidulans in microbiology. *Decellularization of animal-derived tissues ...
Sterigmatocystin
... is mainly produced by the fungi Aspergillus nidulans and A. versicolor. It has been reported in mouldy grain, ... Sterigmatocystin is a polyketide mycotoxin produced by certain species of Aspergillus. The toxin is naturally found in some ... loss of milk production and in some cases death were found to have ingested feed containing Aspergillus versicolor and high ...
Dihydromaltophilin
"Distinct Ceramide Synthases Regulate Polarized Growth in the Filamentous Fungus Aspergillus nidulans". Molecular Biology of the ...
Point mutation
Deletion of the rid homolog in Aspergillus nidulans, dmtA, results in loss of fertility while deletion of the rid homolog in ... "A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans". PLOS ONE. 3 (6): e2531. ...
Georges Delacroix
His name is associated with the mycological species Aspergillus delacroixii (synonym, Aspergillus nidulans var. echinulatus). ... "Recurrent prosthetic valve endocarditis caused by Aspergillus delacroxii (formerly Aspergillus nidulans var. echinulatus)". Med ...
TEAD2
In Aspergillus nidulans, the TEA domain protein ABAA regulates the differentiation of conidiophores. In drosophila the ... "Isolation and physical characterization of three essential conidiation genes from Aspergillus nidulans". Molecular and Cellular ... TEAD proteins were notably found in Drosophila (Scalloped), C. elegans (egl -44), S. cerevisiae and A. nidulans. TEAD2 has been ...
Fungi imperfecti
Thus Aspergillus niger is considered a form taxon. In contrast, isolates of its close relative, Aspergillus nidulans, revealed ... of Penicillium are used to improve both the taste and the texture of cheeses Aspergillus oryzae Aspergillus sojae Aspergillus ... Hence the formerly classified Aspergillus species is now properly called Emericella nidulans. Phylogenetic classification of ... For example, the ubiquitous and industrially important mold, Aspergillus niger, has no known sexual cycle. ...
Fellutamide
Its biosynthetic pathway has been determined in the filamentous fungus Aspergillus nidulans. Aspergillus versicolor Hines J, ... Serial Promoter Exchanges in Aspergillus nidulans Reveal the Biosynthetic Pathway for Fellutamide B, a Proteasome Inhibitor". ...
TEAD1
In Aspergillus nidulans, the TEA domain protein ABAA regulates the differentiation of conidiophores. In drosophila the ... "Isolation and physical characterization of three essential conidiation genes from Aspergillus nidulans". Molecular and Cellular ...
Genome - Simple English Wikipedia, the free encyclopedia
Fungus, Aspergillus nidulans 3×107 Nematode, Caenorhabditis elegans 9.8×107 First multicellular animal genome, December 1998.[ ...
Castor oil
... uvsH diploid strain of Aspergillus nidulans". Anais da Academia Brasileira de Ciências. 76 (1): 49-55. doi:10.1590/S0001- ...
Chaetomium cupreum
"Depression of the xylanase-encoding cgxA gene of Chaetomium gracile in Aspergillus nidulans". Microbiological Research. 153 (4 ...
Genome
December 2005). "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature. 438 ( ...
Dynactin
"Arp11 affects dynein-dynactin interaction and is essential for dynein function in Aspergillus nidulans". Traffic. 9 (7): 1073- ...
Aspergil - Wikipédia
Emericella nidulans (pohlavné rozmnožovanie askospórami). Aspergillus nidulans (nepohlavné rozmnožovanie konídiami) Druh je ... Dovičičová M. (2010): Štúdium potenciálne toxinogénnych druhov rodu Aspergillus a asociovaných teleomorf izolovaných zo zrna ... Rod Aspergillus (Pitt et Hocking, 1999) bol prvýkrát opísaný v roku 1729 talianskym kňazom a mykológom Pierom Antoniom Michelim ... Aspergillus fumigatus (nepohlavné rozmnožovanie konídiami) Druh je heterothalický:. a) v prípade zhodnej časovej a priestorovej ...
Homothallism
"Mating type and the genetic basis of self-fertility in the model fungus Aspergillus nidulans". Current Biology. 17 (16): 1384-9 ... Selfing in the homothallic fungus Aspergillus nidulans involves activation of the same mating pathways characteristic of sex in ... Among those Aspergillus species for which a sexual cycle has been observed, the majority in nature are homothallic (self- ... Dyer PS, O'Gorman CM (January 2012). "Sexual development and cryptic sexuality in fungi: insights from Aspergillus species". ...
Microbial genetics
"Mating type and the genetic basis of self-fertility in the model fungus Aspergillus nidulans". Current Biology. 17 (16): 1384-9 ... Selfing in the homothallic fungus Aspergillus nidulans involves activation of the same mating pathways characteristic of sex in ... Among those Aspergillus species that exhibit a sexual cycle the overwhelming majority in nature are homothallic (self- ... Dyer PS, O'Gorman CM (2012). "Sexual development and cryptic sexuality in fungi: insights from Aspergillus species". FEMS ...
Mating in fungi
"Mating type and the genetic basis of self-fertility in the model fungus Aspergillus nidulans". Current Biology. 17 (16): 1384-9 ... Selfing in the homothallic fungus Aspergillus nidulans involves activation of the same mating pathways characteristic of sex in ... Among the 250 known species of aspergilli, about 36% have an identified sexual state Among those Aspergillus species that ... Dyer PS, O'Gorman CM (January 2012). "Sexual development and cryptic sexuality in fungi: insights from Aspergillus species". ...
კისტური ფიბროზი - ვიკიპედია
... სხვა ფილამენტური სოკოებიდან იშვიათად გვხვდება Aspergillus flavus, Aspergillus nidulans, Exophiala dermatitidis და Scedosporium ... მათ შორისაა ბრონქოპულმონარული ასპერგილოზი, როდესაც ორგანიზმის საპასუხო რეაქცია სოკო Aspergillus fumigatus-ის მიმართ იწვევს ... CF პაციენტების ჰაერგამტარი გზები ასევე შეიძლება იყოს კოლონიზებული ფილამენტური სოკოთი (როგორიცაა Aspergillus fumigatus, ... Scedosporium apiospermum, Aspergillus terreus) და/ან საფუარები (როგორიცაა Candida albicans); ...
真菌 - 维基百科,自由的百科全书
Regulatory circuits of the amdS gene of Aspergillus nidulans. Antonie van Leeuwenhoek. 1994, 65 (3): 179-82. PMID 7847883. doi: ... Identification and toxigenic potential of the industrially important fungi, Aspergillus oryzae and Aspergillus sojae. Journal ... Abe K, Gomi K, Hasegawa F, Machida M. Impact of Aspergillus oryzae genomics on industrial production of metabolites. ... Systemic fungal infections caused by Aspergillus species: epidemiology, infection process and virulence determinants. Current ...
Acetyl-CoA
"ATP-Citrate Lyase Is Required for Production of Cytosolic Acetyl Coenzyme A and Development in Aspergillus nidulans". ...
Sulfite reductase
Yoshimoto A, Nakamura T, Sato R (December 1967). "Isolation from Aspergillus nidulans, of a protein catalyzing the reduction of ...
Aspergillus nidulans
... latus Thom & Raper 1939. Emericella nidulans (Eidam) Vuill. 1927. Diplostephanus nidulans (Eidam) Langeron ... Sterigmatocystis nidulans nicollei Pinoy 1906. Sterigmatocystis nidulans Eidam 1883. Aspergillus nidulans nicollei (Pinoy) ... Aspergillus nidulellus Samson & W. Gams 1986. Emericella nidulans lata (Thom & Raper) Subram. 1972. Emericella nidulans ... An Aspergillus nidulans in nahilalakip ha genus nga Aspergillus, ngan familia nga Trichocomaceae.[2][3] ...
Xenoma, a enciclopedia libre
Aspergillus nidulans 30.000.000 30Mb Nematodo Caenorhabditis elegans 100.300.000 100Mb Primeiro xenoma de animal pluricelular ...
Mudelorganism - Vikipeedia
Aspergillus nidulans. *Coprinus cinereus (seente arengu ja meioosi geneetilised uuringud). *Cunninghamella elegans on seenmudel ...
Aspergillus - Wikipedija, prosta enciklopedija
Aspergillus glaucus. Aspergillus lentulus. Aspergillus nidulans. Aspergillus niger. Aspergillus ochraceus. Aspergillus oryzae. ... Aspergillus restrictus. Aspergillus sojae. Aspergillus sydowii. Aspergillus tamari. Aspergillus terreus. Aspergillus ustus. ... Aspergillus alliaceus. Aspergillus caesiellus. Aspergillus caespitosus. Aspergillus candidus. Aspergillus carneus. Aspergillus ... Aspergillus deflectus. Aspergillus egyptiacus. Aspergillus fischerianus. Aspergillus flavus. Aspergillus foetidus. Aspergillus ...
மரபணுத்தொகை - தமிழ் விக்கிப்பீடியா
பூஞ்சை, Aspergillus nidulans 30,000,000 Nematode, Caenorhabditis elegans 98,000,000 First multicellular animal genome, December ...
Aspergillus fumigatus
The genome sequences of three Aspergillus species-Aspergillus fumigatus, Aspergillus nidulans, and Aspergillus oryzae-were ... Aspergillus fumigatus is a species of fungus in the genus Aspergillus, and is one of the most common Aspergillus species to ... The Aspergillus Trust A registered UK charity engaged in support of sufferers of aspergillus disease worldwide and research ... "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature. 438 (7071): 1105-15. ...
Anidulafungin
The starting material is echinocandin B (a lipopeptide fermentation product of Aspergillus nidulans or the closely related ... It was previously known as LY303366.[3][4][5] It may also have application in treating invasive Aspergillus infection when used ...
Chronic pulmonary aspergillosis
It is very rarely caused by Aspergillus flavus, Aspergillus oryzae, Aspergillus terreus or Aspergillus nidulans. Patients with ... Serum precipitins for aspergillus (blood test to detect antibodies to aspergillus) Almost all aspergillomas are caused by ... is a long-term aspergillus infection of the lung and Aspergillus fumigatus is almost always the species responsible for this ... Aspergillus nodule Chronic cavitary pulmonary aspergillosis (CCPA) where cavities are present in the lungs, but not necessarily ...
Ascomycota
Aspergillus nidulans and Emericella nidulans, for asexual and sexual isolates, respectively, of the same species. ... In Asia, Aspergillus oryzae is added to a pulp of soaked soya beans to make soy sauce, and is used to break down starch in rice ... Most famously, Neurospora crassa, several species of yeasts, and Aspergillus species are used in many genetics and cell biology ... Aspergillus flavus, which grows on peanuts and other hosts, generates aflatoxin, which damages the liver and is highly ...
Ascomycota
Aspergillus nidulans and Emericella nidulans, for asexual and sexual isolates, respectively, of the same species. ... In Asia, Aspergillus oryzae is added to a pulp of soaked soya beans to make soy sauce, and is used to break down starch in rice ... Most famously, Neurospora crassa, several species of yeasts, and Aspergillus species are used in many genetics and cell biology ... Examples of ascomycetes that can cause infections in humans include Candida albicans, Aspergillus niger and several tens of ...
List of sequenced fungi genomes
Aspergillus nidulans Strain:FGSC A4, model organism (2005[20]). *Aspergillus niger Strain:ATCC 1015 (DOE Joint Genome institute ... Aspergillus oryzae Strain:RIB40, industrial use (2005[22]). *Aspergillus terreus NIH 2624, statin producer and pathogen (2005, ... "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature. 438 (7071): 1105-15. ... "Home - Aspergillus carbonarius ITEM 5010 v3". genome.jgi-psf.org. Retrieved 24 November 2018.. ...
Tryptophan synthase
Eckert SC, Kubler E, Hoffmann B, Braus GH (June 2000). "The tryptophan synthase-encoding trpB gene of Aspergillus nidulans is ...
Cyclin-dependent kinase 8
... including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans". Cell Growth & ...
Aspergillus oryzae
December 2005). "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature. 438 ( ... Aspergillus oryzae, known in English as koji (Japanese: 麹, Hepburn: kōji), is a filamentous fungus (a mold) used in Chinese and ... Fujita, Chieko, Tokyo Foundation Koji, an Aspergillus *^ Shurtleff, W.; Aoyagi, A. History of Koji - Grains and/or Soybeans ... Aspergillus oryzae genome from the Database of Genomes Analysed at NITE (DOGAN) ...
Cell cycle
... while fungi such as Aspergillus nidulans and Saccharomyces cerevisiae (yeast) undergo a "closed" mitosis, where chromosomes ...
List of Aspergillus species
Aspergillus neoindicus Aspergillus neoniger Aspergillus neoniveus Aspergillus nidulans Aspergillus nidulellus Aspergillus niger ... U V W X Y Z Aspergillus racemosus Aspergillus raianus Aspergillus rambellii Aspergillus ramosus Aspergillus raperi Aspergillus ... recurvatus Aspergillus rehmii Aspergillus repandus Aspergillus repens Aspergillus reptans Aspergillus restrictus Aspergillus ... U V W X Y Z Aspergillus acidus Aspergillus aculeatinus Aspergillus aculeatus Aspergillus aeneus Aspergillus affinis Aspergillus ...
List of MeSH codes (B05)
... aspergillus fumigatus MeSH B05.381.081.420 - aspergillus nidulans MeSH B05.381.081.450 - aspergillus niger MeSH B05.381.081.480 ... aspergillus ochraceus MeSH B05.381.081.500 - aspergillus oryzae MeSH B05.381.125 - blastomyces MeSH B05.381.128 - botrytis MeSH ... aspergillus MeSH B05.381.081.170 - aspergillus flavus MeSH B05.381.081.295 - ...
BZIP intron RNA motif
Trichoderma reesei and Aspergillus nidulans, Neurospora crassa, Cryptococcus neoformans, Ustilago maydis Plants: Arabidopsis ...
Aspergillus nidulans - Latest research and news | Nature
Aspergillus nidulans. Definition. Aspergillus nidulans is a filamentous soil fungus in the phylum Ascomcyetes. It is a fungal ... Aspernidine A and B, prenylated isoindolinone alkaloids from the model fungus Aspergillus nidulans *Kirstin Scherlach ... its sexual form or teleomorph is known as Emericella nidulans. ...
Aspergillus nidulans - Wikipedia
Aspergillus nidulans (also called Emericella nidulans when referring to its sexual form, or teleomorph) is one of many species ... 2005). "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature. 438 (7071): 1105- ... "Aspergillus nidulans Project Information". Broad Institute. Retrieved 2011-01-28. CS1 maint: discouraged parameter (link) ... Echinocandin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus: isolation and structural components ...
crnA encodes a nitrate transporter in Aspergillus nidulans | PNAS
crnA encodes a nitrate transporter in Aspergillus nidulans - May 15, 1991. *crnA encodes a nitrate transporter in Aspergillus ... crnA encodes a nitrate transporter in Aspergillus nidulans. S E Unkles, K L Hawker, C Grieve, E I Campbell, P Montague, J R ... crnA encodes a nitrate transporter in Aspergillus nidulans. S E Unkles, K L Hawker, C Grieve, E I Campbell, P Montague, J R ... crnA encodes a nitrate transporter in Aspergillus nidulans. S E Unkles, K L Hawker, C Grieve, E I Campbell, P Montague, and J R ...
Aspergillus Nidulans in the CNS
... PLEASE HELP domflag at istar.ca Fri Feb 21 15:55:46 EST 1997 *Previous message: Will NIH ... Infection: Aspergillus Nidulans in the Central Nervous System. The fungus surrounds the base of the brain and is present in ... the biopsy confirmed the fungus was Aspergillus, but the cultures would not grow so it could not be confirmed the fungus was ... Nidulans. An MRI taken February 3, 1997 has shown that the fungus increased in size considerably even with this teatment and ...
Aspergillus nidulans (Eidam) Winter ATCC ® 24766™
Aspergillus nidulans ATCC ® 24766™ Designation: FGSC A158 (ribo1 bi1) Application: Biomedical Research and Development Material ... Aspergillus nidulans (Eidam) Winter (ATCC® 24766™) Alternate State: Emericella nidulans (Eidam) Vuillemin / Strain Designations ... The genetics of Aspergillus nidulans. Adv. Genet. 5: 142-238, 1953. Barratt RW, et al. Wild-type and mutant stocks of ... Aspergillus nidulans. Genetics 52: 233-246, 1965. PubMed: 5857598 Roper JA. Search for linkage between genes determining a ...
Aspergillus nidulans (Eidam) Winter ATCC ® 38163D-2™
Genomic DNA from Aspergillus nidulans strain G00 [ATCC ® 38163™] Application: ... Aspergillus nidulans (Eidam) Winter (ATCC® 38163D-2™) Alternate State: Emericella nidulans (Eidam) Vuillemin / Strain ... Nucleotide (GenBank) : AACD01000000 Aspergillus nidulans FGSC A4, whole genome shotgun sequencing project. ... Genomic DNA from Aspergillus nidulans strain G00 [ATCC® 38163™] / Product Format: dried Total DNA: Approximately 2 µg of DNA. ...
Characterization of the Aspergillus nidulans Septin (asp) Gene Family | Genetics
2000 Landmarks in the early duplication cycles of Aspergillus fumigatus and Aspergillus nidulans: polarity, germ tube emergence ... In Aspergillus nidulans, a brief period of isotropic growth is followed by apical extension of the germ tube (reviewed by H ... 1997 The Aspergillus nidulans septin encoding gene, aspB, is essential for growth. Fungal Genet. Biol. 21: 92-100. ... 1998 hyp loci control cell pattern formation in the vegetative mycelium of Aspergillus nidulans. Genetics 148: 669-680. ...
Aspergillus nidulans - microbewiki
A. nidulans was the first Aspergillus species to have its entire genome sequenced, and considering that A. nidulans is sexually ... www.researchgate.net/figure/Aspergillus-nidulans-var-nidulans-a-e-Teleomorph-and-f-h-Anamorph-a-Ascomata_fig2_259390442 [ ... Aspergillus nidulans. From MicrobeWiki, the student-edited microbiology resource. Revision as of 00:50, 29 January 2020 by ... The use of A. nidulans as a model species allows for the understanding of other Aspergillus species (e.g., A. niger, A. oryzea ...
Identification and characterization of the asperthecin gene cluster of Aspergillus nidulans. - PubMed - NCBI
Identification and characterization of the asperthecin gene cluster of Aspergillus nidulans.. Szewczyk E1, Chiang YM, Oakley CE ... Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans Appl Environ Microbiol. 2008 Dec;74 ... Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans Appl Environ Microbiol. 2008 Dec;74 ... Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans Appl Environ Microbiol. 2008 Dec;74 ...
Metabolites | Free Full-Text | Genetics of Polyketide Metabolism in Aspergillus nidulans
... the attempts being made to trigger the activation of polyketide metabolism in the fungal model organism Aspergillus nidulans. ... Aspergillus nidulans secondary metabolites; polyketides; polyketide synthases; gene clusters; biosynthesis; Aspergillus ... "Genetics of Polyketide Metabolism in Aspergillus nidulans." Metabolites 2, no. 1: 100-133. ... Genetics of Polyketide Metabolism in Aspergillus nidulans. Metabolites. 2012; 2(1):100-133. ...
FluG-Dependent Asexual Development in Aspergillus nidulans Occurs via Derepression | Genetics
Martinelli, S. D., 1994 Aspergillus nidulans as an experimental organism, pp. 33-58 in Aspergillus: 50 Years On (Progress in ... Adams, T. H., J. K. Wieser and J.-H. Yu, 1998 Asexual sporulation in Aspergillus nidulans. Microbiol. Mol. Biol. Rev. 62: 35-54 ... Pontecorvo, G., J. A. Roper, L. M. Hemmons, K. D. Macdonald and A. W. J. Bufton, 1953 The genetics of Aspergillus nidulans. Adv ... Felenbok, B., D. Sequeval, M. Mathieu, S. Sibley, D. I. Gwynne et al., 1988 The ethanol regulon in Aspergillus nidulans: ...
Nuclear movement is beta--tubulin-dependent in Aspergillus nidulans. - PubMed - NCBI
Role of glutamine synthetase in nitrogen metabolite repression in Aspergillus nidulans.
... Margelis S., DSouza C., Small A.J., ... We have isolated the Aspergillus nidulans glnA gene encoding GS and have shown that glnA encodes a highly expressed but not ... However, the A. nidulans fluG gene, which encodes a protein with similarity to prokaryotic GS, did not replace A. nidulans glnA ... Heterologous expression of the prokaryotic Anabaena glnA gene from the A. nidulans alcA promoter allowed full complementation ...
Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia |...
Here, we used whole genome DNA microarrays to investigate global transcriptional changes in Aspergillus... ... Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp. Fungal Genet Biol 46 ... Barratt RW, Johnson GB, Ogata WN (1965) Wild-type and mutant stocks of Aspergillus nidulans. Genetics 52:233-246PubMedGoogle ... David H, Ozçelik IS, Hofmann G, Nielsen J (2008) Analysis of Aspergillus nidulans metabolism at the genome-scale. BMC Genomics ...
Aspergillus nidulans genes encoding reverse transsulfuration enzymes belong to homocysteine regulon | SpringerLink
Homocysteine is an intermediate in methionine synthesis in Aspergillus nidulans, but it can also be converted to cysteine by ... Aspergillus nidulans Transsulfuration Cystathionine β-synthase Cystathionine γ-lyase Regulation by homocysteine ... Pontecorvo G, Roper JA, Hemmons LM, Macdonald KD, Bufton AW (1953) The genetics of Aspergillus nidulans. Adv Genet 5:141-238 ... Natorff R, Sieńko M, Brzywczy J, Paszewski A (2003) The Aspergillus nidulans metR gene encodes a bZIP protein which activates ...
Isolation of a sexual sporulation hormone from Aspergillus nidulans. | Journal of Bacteriology
Isolation and characterisation of the acetyl-CoA carboxylase gene from Aspergillus nidulans
... has been isolated from Aspergillus nidulans. This single-copy gene has an open reading frame (ORF) of 6864 bp and contains two ... Isolation and characterisation of the acetyl-CoA carboxylase gene from Aspergillus nidulans Curr Genet. 1998 Dec;34(5):379-85. ... The putative gene encoding acetyl-CoA carboxylase, accA, has been isolated from Aspergillus nidulans. This single-copy gene has ... Deletion of accA in A. nidulans was unsuccessful. The failure of A. nidulans to grow in the presence of the ACC-specific ...
Catalase activity is necessary for heat-shock recovery in Aspergillus nidulans germlings
... the filamentous fungus Aspergillus nidulans has been chosen as a model system. Here, the response of A. nidulans germlings to ... the filamentous fungus Aspergillus nidulans has been chosen as a model system. Here, the response of A. nidulans germlings to ... Catalase activity is necessary for heat-shock recovery in Aspergillus nidulans germlings Microbiology. 1999 Nov;145 ( Pt 11): ... Treatment with hydrogen peroxide increased A. nidulans germling viability after heat shock whilst mutants deficient in catalase ...
Figure 2 | Immobilization and Biochemical Properties of the Enantioselective Recombinant NStcI Esterase of Aspergillus nidulans
Transcriptomic Analysis Reveals Genes Mediating Salt Tolerance through Calcineurin/CchA-Independent Signaling in Aspergillus...
List of A. nidulans strains used in this study. Table S2. List of primers used in this study. Table S3. Unique significant ... Most enriched GO terms among DEGs induced by salt stress in wild-type A. nidulans. For each enriched GO term with a Bonferroni ... KEGG pathway enrichment of DEGs induced by salt stress in wild-type A. nidulans. The x-axis indicates the enrichment factor of ... Analysis Reveals Genes Mediating Salt Tolerance through Calcineurin/CchA-Independent Signaling in Aspergillus nidulans. Sha ...
Meiotic mutants of Aspergillus nidulans: phenotypes, gene localization and gene cloning.
The tip growth apparatus of Aspergillus nidulans
Role of the Kinesin-like Protein KipB in Aspergillus nidulans
... from Aspergillus nidulans to perfom BLAST searches at the public A. nidulans genome database, at the Whitehead Center for ... In der vorliegenden Arbeit wurde das kinesin-ähnliche Protein, KipB, in Aspergillus nidulans untersucht. KipB gehört zur ... The present work analyses the function of a kinesin-like protein in A. nidulans, KipB, which is a member of the Kip3 kinesin ... To assess the function of KipB kinesin in A. nidulans, a kipB disruption strain was constructed. Analysis of the DkipB mutant ...
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. | Broad Institute
Aspergillus fumigatus, Aspergillus nidulans, Aspergillus oryzae, Base Sequence, Consensus Sequence, Conserved Sequence, ... Here we report the genome sequence of the model organism Aspergillus nidulans, and a comparative study with Aspergillus ... Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.. ... fumigatus, a serious human pathogen, and Aspergillus oryzae, used in the production of sake, miso and soy sauce. Our analysis ...
Transport Assays in Aspergillus nidulans | Aspergillus & Aspergillosis Website
Transport Assays in Aspergillus nidulans. Transport assays allow the direct kinetic analysis of a specific transporter by ... How to cite this protocol: Krypotou, E. and Diallinas, G. (2013). Transport Assays in Aspergillus nidulans. Bio-protocol 3(22 ... Vlanti, A. and Diallinas, G. (2008). The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during ... we describe a rapid and easy method for performing uptake assays in the model filamentous ascomycete Aspergillus nidulans. ...
A Method for the Selection of Deletion Mutations in the L-Proline Catabolism Gene Cluster of Aspergillus nidulans | Genetics...
A Method for the Selection of Deletion Mutations in the L-Proline Catabolism Gene Cluster of Aspergillus nidulans - Volume 38 ... Bailey, C. R. (1977). The regulation of carbon metabolism in Aspergillus nidulans. In Genetics and Physiology of Aspergillus ( ... Pontecorvo, G., Roper, J. A., Hemmons, L. M., Macdonald, K. D. & Bufton, A. W. J. (1953). The genetics of Aspergillus nidulans ... Arst, H. N. Jr., Macdonald, D. W. & Jones, S. A. (1980 b). Regulation of proline transport in Aspergillus nidulans. Journal of ...
The Aspergillus nidulans linkage map
Aspergillus Sequencing Project, Broad Institute/MIT Center for Genome Research. Central Aspergillus Data REpository (CADRE) ... The Aspergillus nidulans Linkage Map. Linkage Data, Maps, Locus Lists, Strainlist and Annual Bibliographies. Compiled by John ... The original linkage maps were published as illustrations to "The Validity of the Aspergillus nidulans Linkage Map" in Fungal ... Gene lists include, as far as possible, all publishedAspergillus (Emericella) nidulans genes, and where available, Genbank ...
Aspergillus nidulans hyphae and sexual spores, SEM - Stock Image C032/3077 - Science Photo Library
... of Aspergillus nidulans hyphae and sexual spores. A. nidulans (also known as Emericella nidulans) is a filamentous fungus that ... as well as metabolism of other Aspergillus species. A. nidulans produces the toxin, sterigmatocysin, which may lead to food ... A. nidulans. has been an important research organism for studying eukaryotic cell biology and has a long history of use for the ... nidulans is also a homothallic fungus, meaning it can form asexual spores by producing conidiphores that bear chains of asexual ...
Production of terpenes with Aspergillus nidulans. | Aspergillus & Aspergillosis Website
Production of terpenes with Aspergillus nidulans.. Kiira Vuoristo, Kirsi Bromann, Mervi Toivari, Laura Ruohonen, Tiina Nakari- ... been widely used in industrial scale production of various compounds and especially Aspergillus niger and Aspergillus nidulans ... Please note: The Aspergillus Website does not accept advertisments. , all content is published on merit. BB.com. Site Sponsors ... Aspergillus Website Newsletters. Our most recent newsletters (since August 2018) can be found here. ...
FungusEmericellaGenesFumigatusFungiMutantsEncodesSpeciesAnalysis of Aspergillus nidulansMetabolism in Aspergillus nidulansGeneticsStrainGenusMutantMutationProteinsConidiaProteinOrganismAspergillosisHyphaeNigerFGSC A4Strains of AspergillusSubstrate specificityRegulationFlavusMicrobiologyBiosynthesisHeterologous expressionGenomicsTranscriptionalPathwaysPolyketideSporesSporulationPathwayPenicilliumLinkage MapGene clusterHyphal growthRepressionAsexualTranscriptionConidiationChromosomesPutativeModelSecondaryPromoter
Fungus37
- Aspergillus nidulans is a filamentous soil fungus in the phylum Ascomcyetes. (nature.com)
- A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner. (wikipedia.org)
- the biopsy confirmed the fungus was Aspergillus, but the cultures would not grow so it could not be confirmed the fungus was Nidulans. (bio.net)
- Five septin genes have been cloned and sequenced from the model filamentous fungus A. nidulans . (genetics.org)
- Although the developmental activator FluG was shown to be necessary for activation of asexual sporulation (conidiation) and production of the carcinogenic mycotoxin sterigmatocystin (ST) in the model filamentous fungus Aspergillus nidulans , the molecular mechanisms underlying the developmental switch have remained elusive. (genetics.org)
- Brody H, Griffith J, Cuticchia AJ, Arnold J, Timberlake WE (1991) Chromosome-specific recombinant DNA libraries from the fungus Aspergillus nidulans . (springer.com)
- Cove DJ (1966) The induction and repression of nitrate reductase in the fungus Aspergillus nidulans . (springer.com)
- To understand the molecular mechanisms induced by stress that contribute to the development of tolerance in eukaryotic cells, the filamentous fungus Aspergillus nidulans has been chosen as a model system. (nih.gov)
- We have investigated the central questions of the roles of cytoskeletal elements and of the precise sites of exocytosis and endocytosis at the growing hyphal tip by using the model fungus Aspergillus nidulans. (ku.edu)
- A. nidulans (also known as Emericella nidulans) is a filamentous fungus that is the only member of the genus Aspergillus that forms sexual spores through meiosis (seen here in this image as large spores). (sciencephoto.com)
- A. nidulans is also a homothallic fungus, meaning it can form asexual spores by producing conidiphores that bear chains of asexual spores. (sciencephoto.com)
- In this study, several aspects of nitrate assimilation and transport have been studied using the filamentous fungus Aspergillus nidulans, which has been shown to be safe laboratory organism as judged by it's pathogenicity towards insect larvae. (aspergillus.org.uk)
- We have developed an efficient system for amplifying genes from a target fungus, placing them under control of a regulatable promoter, transferring them into A. nidulans and expressing them. (ku.edu)
- In this study, we designed three regulation strategies for laccase gene expression in the model fungus Aspergillus nidulans . (springer.com)
- By introducing various promoters in front of the laccase gene pslcc from the white-rot fungus Pycnoporus sanguineus , we found that the laccase gene with the original promoter had effective expression in A. nidulans . (springer.com)
- Taken together, these results not only demonstrate an efficient system for heterologous protein production in the model fungus A. nidulans but also provide a general approach to applying regulatory methods to control gene expression. (springer.com)
- This makes A. nidulans the first fungus in which all members of individual Pmt subfamilies can be deleted without loss of viability. (pubmedcentralcanada.ca)
- Two Aspergillus nidulans genes, xlnA and xlnB, encoding the X22 and X24 xylanases from this fungus, respectively, have been cloned and sequenced. (asm.org)
- We have used an Aspergillus nidulans macroarray carrying sequences of 2,787 genes from this fungus to monitor gene expression of both wild-type and uvsB ATR (the homologue of the ATR gene) deletion mutant strains in a time course exposure to camptothecin (CPT). (unl.edu)
- We report here probable nutrient-sensing signal transduction pathways in Aspergillus nidulans, a model filamentous fungus, based on sequence homology studies with known Saccharomyces cerevisiae and Schizosaccharomyces pombe proteins. (iospress.com)
- Aspergillus nidulans is a filamentous fungus of considerable biological interest which provides an excellent model system for investigating different aspects of drug resistance in filamentous fungi. (asm.org)
- Five major histone proteins have been extracted from chromatin isolated from purified nuclei of the fungus, Aspergillus nidulans. (rupress.org)
- Aspergillus is able to secrete enzymes that can hydrolyse polysaccharides into pentoses and hexoses [ 1 ], which can be taken up by the fungus. (biomedcentral.com)
- The filamentous fungus Aspergillus nidulans senses red using the red light receptor, phytochrome (FphA). (kit.edu)
- We explored these connections by characterizing the septin AspB and its interaction with actin and microtubules in the filamentous fungus Aspergillus nidulans. (uga.edu)
- Inducible alkyltransferase DNA repair proteins in the filamentous fungus Aspergillus nidulans. (openrepository.com)
- We have investigated the response of the filamentous fungus Aspergillus nidulans to low, non-killing, doses of the alkylating agent MNNG (N-methyl-N'-nitro-N-nitrosoguanidine). (openrepository.com)
- The first global genomic, proteomic, and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the International Space Station (ISS) is reported. (cdc.gov)
- We have been investigating the mechanisms underlying the regulation of asexual development (conidiation) and gliotoxin biosynthesis in A. fumigatus, primarily focusing on a characterization of key developmental regulators identified in the model fungus Aspergillus nidulans . (bvsalud.org)
- To address our hypotheses , we have studied fungi and cell wall material properties of the model fungus , Aspergillus nidulans , under autophagic conditions . (umbc.edu)
- Antibiofilm, antiproliferative, antioxidant and antimutagenic activities of an endophytic fungus aspergillus fumigatus From Moringa oleifera. (greenmedinfo.com)
- In this study we examined whether adaptation, measured as an increased mycelial growth rate, has correlated responses in the filamentous fungus Aspergillus nidulans with several other metric characters that could be important fitness components (colony forming units, germination speed, and biomass formation). (wur.nl)
- A mutant that presents increased production of the melanin pigment was isolated from the Aspergillus nidulans fungus. (unesp.br)
- The attainment of this pigment, in its pure form, has taken biotechnological interest due to its use in cosmetic formulations, mainly for its photoprotector and antioxidant property .Considering the pharmacological potential of the melanin pigment, this study aims to make the structural and functional characterization of the pigment extracted from A. nidulans fungus. (unesp.br)
- The results of mass spectrometry indicate that the melanin structure of the A. nidulans fungus is composed of two large units, represented by the fragments of molecular mass equal to 573 and 550, with dihydroxyindole groups and substituted pyrrolic rings. (unesp.br)
- The cytotoxicity assays have shown that the melanin extracted from the A. nidulans fungus does not cause significant damages to the cellular components, before and after metabolization. (unesp.br)
- Aspergillus rugulosus is a species of fungus in the genus Aspergillus. (wikipedia.org)
Emericella4
- its sexual form or teleomorph is known as Emericella nidulans. (nature.com)
- Aspergillus nidulans (also called Emericella nidulans when referring to its sexual form, or teleomorph) is one of many species of filamentous fungi in the phylum Ascomycota. (wikipedia.org)
- Gene lists include, as far as possible, all published Aspergillus (Emericella) nidulans genes, and where available, Genbank accession numbers and the closest fitting autocalled genes from the Broad Institute genome sequence. (fgsc.net)
- Make an adhesive tape preparation of Emericella nidulans (Cleistothecia) substituting KOH for LPCB. (blogspot.com)
Genes19
- Interest in the selection of mutations affecting L-proline catabolism in Aspergillus nidulans is heightened by the involvement of one of the very few examples of a cluster of functionally related genes in an eukaryote and by an increasing awareness of the biological phenomena in which proline and proline catabolism participate. (cambridge.org)
- In silico analysis of the A. nidulans genome sequence, identified two putative genes designated cnxL and cnxK that might be involved in molybdenum cofactor (a component of nitrate reductase) biosynthesis as well as two putative nitrate reductases encoding genes niaB and niaC. (aspergillus.org.uk)
- Eisendle, M., Oberegger, H., Zadra, I. and Haas, H. (2003) The Siderophore System Is Essential for Viability of Aspergillus nidulans Functional Analysis of Two Genes Encoding L-Ornithine N5-Monooxygenase (sidA) and a Non-Ribosomal Peptide Synthetase (sidC). (scirp.org)
- We have validated this system by expressing non-reducing polyketide synthases of Aspergillus terreus and additional genes required for compound production and release. (ku.edu)
- Isolation and physical characterization of three essential conidiation genes from Aspergillus nidulans. (asm.org)
- We cloned and characterized three genes from Aspergillus nidulans, designated brlA, abaA, and wetA, whose activities are required to complete different stages of conidiophore development. (asm.org)
- Molecular cloning and expression in Saccharomyces cerevisiae of two Aspergillus nidulans xylanase genes. (asm.org)
- The major fungal pathogen of humans, Aspergillus fumigatus , lacks a defined sexual cycle, although the presence of genes encoding putative mating type idiomorphs and regulators of Aspergillus sexual development heightens the potential for cryptic sexuality in this deuteromycete. (asm.org)
- From genome sequence analyses of the homothallic model ascomycete, A. nidulans , genes encoding α-box and HMG-domain proteins ( matB and matA , respectively) were both found to be present and necessary for sexual reproduction ( 30 ). (asm.org)
- Here, we evaluate the potential of real-time RT-PCR to quantify the relative transcript levels of ABC transporter Atr genes from Aspergillus nidulans . (asm.org)
- We also verified the relative transcript levels of the Atr genes in the A. nidulans imazalil-resistant mutants. (asm.org)
- FacB, the Aspergillus nidulans activator of acetate utilization genes, binds dissimilar DNA sequences. (semanticscholar.org)
- Here, we summarize current progress towards understanding the function of these genes and the mechanisms involved in polarized hyphal growth and septation in A. nidulans. (nebraska.edu)
- Several promoter regions of the trpC and crp genes were fused to the npgA gene containing the 1,034-bp open reading frame and the 966-bp 3' downstream region from the TAA, and the constructed fusions were introduced into the NPG mutant in A. nidulans to evaluate color recovery due to the transcriptional activity of the sequence elements. (bvsalud.org)
- Assigning functions to newly discovered genes constitutes one of the major challenges en route to fully exploiting the data becoming available from the genome sequencing initiatives. (chalmers.se)
- In parallel, we produced defined mutant derivatives of mpaC, and the combined analysis of A. nidulans strains expressing mpaC or mutated mpaC genes unequivocally demonstrated that mpaC indeed encodes a polyketide synthase that produces the first intermediate in the production of the medically important immunosuppressant mycophenolic acid. (chalmers.se)
- Aspergillus nidulans possesses threepmt genes encoding protein O-D-mannosyltransferases (Pmt). (elsevier.com)
- DNA microarray analyses for Aspergillus nidulans FGSCA26 (WT) strain and Gene disruptant of sirA (SirAd) indicated that genes for synthesizing secondary metabolic products such as sterigmatocystin, penicillin G, emericellamide, aspernidine A, xanthone, austinol, and siderophores are down-regulated by SirA. (omicsdi.org)
- Kraus, PR & Harris, SD 2001, ' The Aspergillus nidulans snt genes are required for the regulation of septum formation and cell cycle checkpoints ', Genetics , vol. 159, no. 2, pp. 557-569. (elsevier.com)
Fumigatus16
- Here we report the genome sequence of the model organism Aspergillus nidulans, and a comparative study with Aspergillus fumigatus, a serious human pathogen, and Aspergillus oryzae, used in the production of sake, miso and soy sauce. (broadinstitute.org)
- 2016). Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus. (springer.com)
- Biochemical and antigenic characterization of a new dipeptidyl-peptidase isolated from Aspergillus fumigatus. (springer.com)
- To test the functionality of these genetic determinants, we transferred the alpha box-encoding mat1-1 idiomorph from an A. fumigatus isolate to the homothallic fertile species Aspergillus nidulans . (asm.org)
- Moreover, phylogenetic analyses support the occurrence of genetic recombination within the Aspergillus fumigatus population ( 32 ). (asm.org)
- As deduced from in silico analyses, the genome of the A. fumigatus sequence reference strain Af293 contains many putative gene products that are orthologous to recognized determinants of fruiting body formation in the fertile species Aspergillus nidulans ( 10 , 27 ). (asm.org)
- The emergence of azole resistance in Aspergillus fumigatus as well as an increasing frequency of multiresistant cryptic Aspergillus spp. (asm.org)
- We studied the in vivo efficacy of olorofim intraperitoneal therapy (15 mg/kg of body weight every 8 h for 9 days) against infection with A. fumigatus , A. nidulans , and A. tanneri in both neutropenic CD-1 mice and mice with chronic granulomatous disease (CGD) ( gp91 −/− phox mice). (asm.org)
- The primary etiologic agent of IA in both neutropenic and CGD patient populations is Aspergillus fumigatus ( 5 - 7 ). (asm.org)
- In addition, IA remains the primary cause of morbidity and mortality in CGD patients and is often due to non- fumigatus Aspergillus spp. (asm.org)
- Study of the essentiality of the Aspergillus fumigatus triA gene, encoding RNA triphosphatase, using the heterokaryon rescue technique and the conditional gene expression driven by the alcA and niiA promoters. (semanticscholar.org)
- It has also been shown that growth of an A. fumigatus Δ hxkA Δ glkA strain is reduced on D-glucose and D-fructose [ 8 ] and that the A. nidulans hxkA1 glkA1 mutant is unable to phosphorylate D-glucose and D-fructose [ 5 ]. (biomedcentral.com)
- Importantly, the opportunistic human pathogen Aspergillus fumigatus has become the most prevalent airborne fungal pathogen in developed countries , causing invasive aspergillosis in immunocompromised patients with a high mortality rate. (bvsalud.org)
- Honokiol reduces fungal load and inflammatory cytokines in aspergillus fumigatus keratitis. (greenmedinfo.com)
- Perillaldehyde ameliorates aspergillus fumigatus keratitis. (greenmedinfo.com)
- Aspergillus Mix with NDC 22840-9628 is a a non-standardized allergenic label product labeled by Greer Laboratories, Inc.. The generic name of Aspergillus Mix is aspergillus amstelodami, aspergillus flavus, aspergillus fumigatus, aspergillus nidulans and aspergillus niger. (ndclist.com)
Fungi14
- A. nidulans is a form of filamentous fungi that has been found to serve as a valuable model organism in the realm of eukaryotic cell biology. (kenyon.edu)
- Members of the genus Aspergillus are the most common fungi and many are beneficial to humans. (genetics.org)
- There are not many reports on microbial transformation of terpenoids by fungi of the Aspergillus genus, although their ability to transform terpenes is recognised. (aspergillus.org.uk)
- Filamentous fungi have been widely used in industrial scale production of various compounds and especially Aspergillus niger and Aspergillus nidulans represent potential host organisms for the production and modification of various terpenoid products. (aspergillus.org.uk)
- In recent decades, pathogenic fungi, such as Aspergillus spp. (asm.org)
- An Aspergillus nidulans [1] in uska species han Fungi in nahilalakip ha divisio nga Ascomycota , ngan nga syahan ginhulagway ni Eduard Eidam , ngan ginhatag han pagkayana nga asya nga ngaran ni Georg Winter hadton 1884. (wikipedia.org)
- The genomes of filamentous fungi such as A. nidulans encode a multiplicity of sugar transporters with broad affinities for hexose and pentose sugars. (biomedcentral.com)
- Amongst these fungi, Aspergillus nidulans has proven to be a particularly valuable model. (nebraska.edu)
- To develop a convenient promoter analysis system for fungi, a null-pigment mutant (NPG) of Aspergillus nidulans was used with the 4′-phosphopantetheinyl transferase (PPTase) gene, npgA, which restores the normal pigmentation in A. nidulans, as a new reporter gene. (bvsalud.org)
- The functional organization of serially deleted promoter regions of the A. nidulans trpC gene and the Cryphonectria parasitica crp gene in filamentous fungi was representatively investigated to establish a novel fungal promoter assay system that depends on color complementation of the NPG mutant with the PPTase npgA gene. (bvsalud.org)
- To facilitate the use of filamentous fungi in functional genomics, we present a versatile cloning system that allows a gene of interest to be expressed from a defined genomic location of Aspergillus nidulans. (chalmers.se)
- Members of the genus Aspergillus are the most common fungi and all reproduce asexually by forming long chains of conidiospores (or conidia ). (bvsalud.org)
- Bailey, AM 1992, Assimilatory sulphate reduction in the filamentous fungi Aspergillus nidulans and Penicillium chrysogenum . (bris.ac.uk)
- Sterigmatocystin is mainly produced by the fungi Aspergillus nidulans and A. versicolor. (wikipedia.org)
Mutants10
- Treatment with hydrogen peroxide increased A. nidulans germling viability after heat shock whilst mutants deficient in catalase were more sensitive to a 50 degrees C heat exposure. (nih.gov)
- Meiotic mutants of Aspergillus nidulans: phenotypes, gene localization and gene cloning. (wur.nl)
- At elevated temperatures, all A. nidulans Δ pmt mutants show cell wall-associated defects and increased sensitivity to cell wall-perturbing agents. (pubmedcentralcanada.ca)
- The altered developmental patterns in Δ pmt mutants suggest that A. nidulans Pmts modify proteins that serve as spatial cues. (pubmedcentralcanada.ca)
- NsdD acts positively on early steps of sexual reproduction in A. nidulans without affecting asexual conidiation, as demonstrated by analysis of deletion mutants and overexpression studies ( 16 ). (asm.org)
- Employing a collection of temperature sensitive nuclear distribution (nudA2, nudC3 and nudF7), nuclear division (nimA5, hfaB3), and septation (sepD5, sepG1) mutants, we have investigated the interdependency among nuclear positioning, mitosis, and cell growth in structuring the cellular compartments of A. nidulans. (biologists.org)
- Molecular characterization of mutants of the acetate regulatory gene facB of Aspergillus nidulans. (semanticscholar.org)
- Recently, a novel YAP-like bZIP, restorer of secondary metabolism A (RsmA), was found in a suppressor screen of an Aspergillus nidulans secondary metabolism (SM) mutant in which overexpression of rsmA was found to partially remediate loss of SM in Velvet Complex mutants. (microbiologyresearch.org)
- Here we characterized and contrasted SM in mutants of RsmA and four other A. nidulans bZIP proteins (NapA, ZipA, ZipB and ZipC) with predicted DNA binding motifs similar to RsmA. (microbiologyresearch.org)
- Previous phenotypic analysis of glucokinase and hexokinase mutants from Aspergillus nidulans demonstrated that at least one of them is required for normal growth on D-fructose or D-glucose. (biomedcentral.com)
Encodes8
- We report that the deletion of sumO, the gene that encodes the small ubiquitin-like protein SUMO in A. nidulans, caused a dramatic increase in the production of the secondary metabolite asperthecin and a decrease in the synthesis of austinol/dehydroaustinol and sterigmatocystin. (nih.gov)
- We have isolated the Aspergillus nidulans glnA gene encoding GS and have shown that glnA encodes a highly expressed but not highly regulated mRNA. (uniprot.org)
- However, the A. nidulans fluG gene, which encodes a protein with similarity to prokaryotic GS, did not replace A. nidulans glnA function when similarly expressed. (uniprot.org)
- Fidel S, Doonan JH, Morris NR (1988) Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a gamma-actin. (springer.com)
- The Aspergillus nidulans acuL gene encodes a mitochondrial carrier required for the utilization of carbon sources that are metabolized via the TCA cycle. (semanticscholar.org)
- The facC gene of Aspergillus nidulans encodes an acetate-inducible carnitine acetyltransferase. (semanticscholar.org)
- In this study, we identified the A. nidulans xtrD ( x ylose tr ansporter) gene, which encodes a Major Facilitator Superfamily (MFS) transporter, and which was specifically induced at the transcriptional level by xylose in a XlnR-dependent manner, while being partially repressed by glucose in a CreA-dependent manner. (biomedcentral.com)
- The facB gene of Aspergillus nidulans encodes a DNA binding transcriptional activator required for growth on acetate as a sole carbon source. (edu.au)
Species18
- Selfing in A. nidulans involves activation of the same mating pathways characteristic of sex in outcrossing species, i.e. self-fertilization does not bypass required pathways for outcrossing sex but instead requires activation of these pathways within a single individual. (wikipedia.org)
- 5] As a model organism, this species' diversified genome (unlike its relatives) allows for a more developed understanding of other species in the Aspergillus genus. (kenyon.edu)
- A. nidulans was the first Aspergillus species to have its entire genome sequenced, and considering that A. nidulans is sexually reproductive, it contains a well-developed genetics system. (kenyon.edu)
- A. nidulans is capable of producing sexual spores via meiosis, which allows for a more diversified collection of strains for the species. (kenyon.edu)
- Systematics of Aspergillus species of subgenus Nidulantes in Iran - Scientific Figure on ResearchGate. (kenyon.edu)
- Species in the genus Aspergillus are commonly found in many areas of life on earth, such as in soil, plant debris, water (freshwater or marine), or the air. (kenyon.edu)
- The use of A. nidulans as a model species allows for the understanding of other Aspergillus species (e.g. (kenyon.edu)
- A. nidulans is the only species of the Aspergilli that is not asexual. (kenyon.edu)
- Andersen MR, Vongsangnak W, Panagiotou G, Salazar MP, Lehmann L, Nielsen J (2008) A trispecies Aspergillus microarray: comparative transcriptomics of three Aspergillus species. (springer.com)
- has been an important research organism for studying eukaryotic cell biology and has a long history of use for the study of a wide range of subjects including basic genetic problems (recombination, DNA repair, mutation), cell cycle control and pathogenesis, as well as metabolism of other Aspergillus species. (sciencephoto.com)
- Aspergillus species may be homothallic or heterothallic ( 8 ). (asm.org)
- CGD patients may also suffer from infections due to less common species, such as A. nidulans ( 8 ) and A. tanneri ( 9 ). (asm.org)
- Involvement of a particular species of beta-tubulin (beta 3) in conidial development in Aspergillus nidulans. (rupress.org)
- A comparison of interspecific hybrids within the Aspergillus nidulans species group was made by isoenzyme analysis. (elsevier.com)
- The results indicate a certain degree of genetic homology among the members of the Aspergillus nidulans species group. (elsevier.com)
- The impact of various Aspergillus species on humans ranges from beneficial to harmful. (bvsalud.org)
- For example, several species including Aspergillus oryzae and Aspergillus niger are used in industry for enzyme production and food processing . (bvsalud.org)
- Sterigmatocystin is a polyketide mycotoxin produced by certain species of Aspergillus. (wikipedia.org)
Analysis of Aspergillus nidulans2
- Analysis of Aspergillus nidulans metabolism at the genome-scale. (kenyon.edu)
- Transcriptome Analysis of Aspergillus nidulans Exposed to Campt" by Iran Malazavi, Marcela Savoldi et al. (unl.edu)
Metabolism in Aspergillus nidulans1
- Role of carnitine acetyltransferases in acetyl coenzyme A metabolism in Aspergillus nidulans. (semanticscholar.org)
Genetics2
- The genetics of Aspergillus nidulans. (atcc.org)
- The original linkage maps were published as illustrations to "The Validity of the Aspergillus nidulans Linkage Map" in Fungal Genetics and Biology 21 , (1997) 267-277, and are reproduced here, with modifications, by permission of Academic Press. (fgsc.net)
Strain5
- To assess the function of KipB kinesin in A. nidulans, a kipB disruption strain was constructed. (uni-marburg.de)
- The catabolism of glucose and xylose was studied in a wild type and creA deleted (carbon catabolite de-repressed) strain of Aspergillus nidulans. (dtu.dk)
- Here we evaluated if it would be possible to create an Aspergillus nidulans strain that releases, but does not metabolize hexoses from plant biomass. (biomedcentral.com)
- A haploid strain of the Aspergillus nidulans carried the auxotrophic met-eight mutation conferring a requirement for methionine. (mywordsolution.com)
- Investigation of whole genome gene expression level changes in Aspergillus nidulans AN1599 (PbcR) overexpression mutant, compared to the FGSC A4 wild-type strain. (omicsdi.org)
Genus2
- This sort of reproduction is not common within the Aspergillus genus. (kenyon.edu)
- An Aspergillus nidulans in nahilalakip ha genus nga Aspergillus , ngan familia nga Trichocomaceae . (wikipedia.org)
Mutant5
- Wild-type and mutant stocks of Aspergillus nidulans. (atcc.org)
- Barratt RW, Johnson GB, Ogata WN (1965) Wild-type and mutant stocks of Aspergillus nidulans . (springer.com)
- Here, we report the isolation and characterization of Aspergillus nidulans strains carrying conditional ( cfwA2 ) and null (Δ cfwA ) mutant alleles of the cfwA gene, encoding an essential PPTase. (asm.org)
- The effects of the inhibitors proflavine and phenylmercuric acetate upon germination of conidia of a mutant of Aspergillus nidulans were investigated. (mun.ca)
- The investigation included the A. nidulans wild-type and three mutant strains, two of which were genetically engineered to enhance secondary metabolite production. (cdc.gov)
Mutation7
- For the last 50 years, A. nidulans has been used to study a wide array of processes and topics such as cell cycles, DNA repair, nucleokinesis, pathogenesis, mutation, and evolutionary processes. (kenyon.edu)
- Heterologous expression of the prokaryotic Anabaena glnA gene from the A. nidulans alcA promoter allowed full complementation of the A. nidulans glnADelta mutation. (uniprot.org)
- DkipB heterozygous strains showed an increased instability of diploid nuclei, which proved once more KipB involvement in mitosis, along with DkipB clear genetic interaction with a mutation in another mitotic kinesin in A. nidulans, bimC4. (uni-marburg.de)
- The sas A-60 (semialdehyde sensitive) mutation in A. nidulans results in toxicity of catabolic precursors of L-glutamic γ-semialdehyde (or its internal Schiff base L-Δ 1 -pyrroline-5-carboxylate) and succinic semialdehyde, apparently without affecting the catabolic pathways concerned. (cambridge.org)
- The Aspergillus nidulans acuH gene, required for growth on acetate and long-chain fatty acids, was cloned by complementation of the acuH13 mutation. (semanticscholar.org)
- Strains of Aspergillus containing the benA22 mutation are resistant to benomyl for vegetative growth but do not produce conidia. (rupress.org)
- The pattern of degeneration suggested That a process similar to the repeat-induced point- mutation (RIP) phenomenon, first described in Neurospora crassa, may have operated in A. nidulans. (forskningsdatabasen.dk)
Proteins6
- Finally, the effects of potential nitrate transport inhibitors were studied on net nitrate transport by NrtA and NrtB proteins of A. nidulans. (aspergillus.org.uk)
- The Δ pmt phenotypes at elevated temperatures, increased sensitivity to cell wall-perturbing agents and restoration to wild-type growth with osmoticum suggest that A. nidulans Pmts modify proteins in the cell wall integrity pathway. (pubmedcentralcanada.ca)
- Specifically, we identified A. nidulans homologs for yeast proteins involved in (1) filamentation-invasion, (2) cAMP-PKA, (3) pheromone response, (4) cell integrity and (5) TOR signaling pathways. (iospress.com)
- We note that by using a highly conservative approach, 70% of the S. cerevisiae signal transduction proteins (107 proteins out of 153 proteins studied) have significant homologs in A. nidulans. (iospress.com)
- Electrophoresis of these proteins in three different systems (urea-starch, urea-acetic acid polyacrylamide, and discontinuous SDS polyacrylamide) showed that the A. nidulans histones H3 and H4 were nearly identical to calf thymus H3 and H4 with respect to net charge and molecular weight criteria, whereas the fungal histones H1, H2a and H2b were similar but not identical to the corresponding calf thymus histones. (rupress.org)
- The mobility patterns of A. nidulans ribosomal basic proteins in three different electrophoretic systems were distinctly different from those of the fungal histones. (rupress.org)
Conidia2
- The germ tubes of A. nidulans conidia grew exponentially at a rate which was about 2·3 times as great as the specific growth rate of the organism in submerged culture. (microbiologyresearch.org)
- In Aspergillus nidulans, germinating conidia undergo multiple rounds of nuclear division before forming a septum. (elsevier.com)
Protein6
- The present work analyses the function of a kinesin-like protein in A. nidulans, KipB, which is a member of the Kip3 kinesin family. (uni-marburg.de)
- E ntry into mitosis in Aspergillus nidulans is regulated by the coordinate function of two serine/threonine protein kinases, NIMX CDC2 and NIMA. (rupress.org)
- In Aspergillus nidulans a combination of null mutations in halA, encoding a protein kinase, and sltA, encoding a zinc-finger transcription factor having no yeast homologues, results in an elevated calcium requirement ('calcium auxotrophy') without impairing net calcium uptake. (core.ac.uk)
- Identification and characterization of two Ca2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans. (duke.edu)
- We utilized an expression screen to identify two novel Ca(2+)/calmodulin (CaM)-regulated protein kinases in Aspergillus nidulans. (duke.edu)
- A recombinant dimeric protein of A. nidulans glutathione reductase (GR) contained FAD and reduced oxidized glutathione (GSSG) using NADPH as an electron donor. (core.ac.uk)
Organism2
- This review covers the attempts being made to trigger the activation of polyketide metabolism in the fungal model organism Aspergillus nidulans . (mdpi.com)
- This study investigated glutathione-dependent mechanisms in the model organism Aspergillus nidulans. (core.ac.uk)
Aspergillosis1
- There are very few cases of invasive aspergillosis reported in children during induction chemotherapy for acute leukemia and A. nidulans is rare in the absence of chronic granulomatous disease. (ox.ac.uk)
Hyphae1
- Coloured scanning electron micrograph (SEM) of Aspergillus nidulans hyphae and sexual spores. (sciencephoto.com)
Niger1
- Production of the Phanerochaete flavido-alba laccase in Aspergillus niger for synthetic dyes decolorization and biotransformation. (springer.com)
FGSC A41
- AACD01000000 Aspergillus nidulans FGSC A4, whole genome shotgun sequencing project. (atcc.org)
Strains of Aspergillus1
- Strains of Aspergillus nidulans with chromosome duplications are unstable at mitosis. (newprairiepress.org)
Substrate specificity1
- This study characterized the regulation and substrate specificity of an A. nidulans transporter that represents a good candidate for further directed mutagenesis. (biomedcentral.com)
Regulation2
- Conidiation in A. nidulans involves many common developmental themes including spatial and temporal regulation of gene expression, specialized cellular differentiation, and intercellular communication. (genetics.org)
- pH regulation of gene expression in the mold Aspergillus nidulans is one such example. (asm.org)
Flavus1
- In contrast, Aspergillus flavus produce the most potent naturally present carcinogen aflatoxins , which contaminate various plant - and animal -based foods . (bvsalud.org)
Microbiology1
- Kalman, ET , Varga, J & Kevei, F 1991, ' Characterization of interspecific hybrids within the Aspergillus nidulans group by isoenzyme analysis ', Canadian Journal of Microbiology , vol. 37, no. 5, pp. 391-396. (elsevier.com)
Biosynthesis2
- Proposed biosynthesis pathway for asperthecin (4) in A. nidulans . (nih.gov)
- Our results expand the number of known and predicted secondary metabolites requiring CfwA/NpgA for their biosynthesis and, together with the phylogenetic analysis of fungal PPTases, suggest that a single PPTase is responsible for the activation of all PKSs and NRPSs in A. nidulans . (asm.org)
Heterologous expression1
- To access these potentially valuable, cryptic clusters, we have developed a heterologous expression system in Aspergillus nidulans. (ku.edu)
Genomics1
- International Space Station conditions alter genomics, proteomics, and metabolomics in Aspergillus nidulans. (cdc.gov)
Transcriptional3
- Here, we used whole genome DNA microarrays to investigate global transcriptional changes in Aspergillus nidulans gene expression after exposure to hypoxia followed by normoxia. (springer.com)
- This study is the first to show that hypoxia elicits systematic transcriptional responses in A. nidulans . (springer.com)
- The major transcriptional repressor for carbon catabolite repression in Aspergillus nidulans is CreA, and mutational analysis led to the suggestion that a regulatory ubiquitination/deubiquitination pathway is involved. (usda.gov)
Pathways4
- The sequencing of Aspergillus genomes has revealed that the products of a large number of secondary metabolism pathways have not yet been identified. (nih.gov)
- Based on these results, probable pathways in A. nidulans were constructed using well-established S. cerevisiae and S. pombe models. (iospress.com)
- The patient populations at the highest risk for IA are those with prolonged neutropenia from intensive myeloablative chemotherapy and those with inborn errors of immunity that impair key innate anti- Aspergillus host defense pathways, such as chronic granulomatous disease (CGD) ( 3 , 4 ). (asm.org)
- Aspergillus then uses a variety of catabolic pathways to efficiently convert all monomeric components of plant biomass. (biomedcentral.com)
Polyketide1
- Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans. (springer.com)
Spores1
- The wild type genotype of A. nidulans is green due to the coloration of its spores, but this color may vary amongst differing strains. (kenyon.edu)
Sporulation2
- Asexual Sporulation in Aspergillus nidulans. (kenyon.edu)
- Isolation of a sexual sporulation hormone from Aspergillus nidulans. (asm.org)
Pathway3
- Homocysteine is an intermediate in methionine synthesis in Aspergillus nidulans , but it can also be converted to cysteine by the reverse transsulfuration pathway involving cystathionine β-synthase (CBS) and cystathionine γ-lyase (CGL). (springer.com)
- KEGG pathway enrichment of DEGs induced by salt stress in wild-type A. nidulans. (hindawi.com)
- Activation of the pathway in Aspergillus nidulans lead to a production of ent-pimara-8(14),15-diene. (omicsdi.org)
Penicillium2
- SUMMARY: The growth kinetics of Aspergillus nidulans, Mucor hiemalis and Penicillium chrysogenum on solid media and in submerged culture were studied. (microbiologyresearch.org)
- We have demonstrated the potential of the system by transferring the 7,745-bp large mpaC gene from Penicillium brevicompactum to A. nidulans. (chalmers.se)
Linkage Map2
- The validity of the Aspergillus nidulans linkage map. (mysciencework.com)
- The Aspergillus nidulans linkage map is reviewed as a background to physical mapping by cosmid cross-hybridization and genome sequencing. (mysciencework.com)
Gene cluster3
- Identification and characterization of the asperthecin gene cluster of Aspergillus nidulans. (nih.gov)
- A) Organization of the asperthecin synthase gene cluster in A. nidulans . (nih.gov)
- Overexpression of the Zn(II)2Cys6 -type transcription factor, AN1599.4 (PbcR, pimaradiene biosynthetic cluster regulator), activates a secondary metabolite gene cluster in Aspergillus nidulans. (omicsdi.org)
Hyphal growth1
- We investigated the roles of actin (ActA) and fimbrin (FimA) in hyphal growth in Aspergillus nidulans. (psu.edu)
Repression1
- Role of glutamine synthetase in nitrogen metabolite repression in Aspergillus nidulans. (uniprot.org)
Asexual1
- The asexual reproductive cycle of A. nidulans begins and ends with the asexual spore called the conidium and can be divided into two distinct phases, growth and development. (genetics.org)
Transcription2
- These functions were resumed by re-oxygenation, indicating that A. nidulans controls global transcription to adapt to a hypoxic environment. (springer.com)
- The Aspergillus nidulans zinc finger transcription factor PacC is activated by proteolytic processing in response to ambient alkaline pH. (asm.org)
Conidiation1
- In this study, we report that the FluG-mediated conidiation in A. nidulans occurs via derepression. (genetics.org)
Chromosomes2
- For all eight chromosomes of A. nidulans a reliable framework has been provided by analysis of mitotic crossing over, in many cases substantiated by the study of translocation disomics. (mysciencework.com)
- The isoenzyme composition of the haploid segregants of the Aspergillus nidulans x Aspergillus rugulosus hybrid differed for some of the enzymes studied from that of the hybrid, suggesting that during segregation further interaction of the chromosomes took place. (elsevier.com)
Putative2
- The putative gene encoding acetyl-CoA carboxylase, accA, has been isolated from Aspergillus nidulans. (nih.gov)
- We used the motor domain of conventional kinesin (KinA) from Aspergillus nidulans to perfom BLAST searches at the public A. nidulans genome database, at the Whitehead Center for Genome Research (Cambridge USA), and identified eleven putative kinesin motors. (uni-marburg.de)
Model1
- In this protocol, we describe a rapid and easy method for performing uptake assays in the model filamentous ascomycete Aspergillus nidulans. (aspergillus.org.uk)
Secondary1
- A twelve array study using total RNA recovered from six separate cultures of Aspergillus nidulans wild-type RDIT9.32 (veA) and six separate cultures of Aspergillus nidulans overexpressing rsmA (restorer of secondary metabolism A), using custom-designed, four-plex arrays. (omicsdi.org)
Promoter1
- In the first run, three biological replicates each of Aspergillus nidulans wild-type RDIT9.32 (veA) and Aspergillus nidulans carrying a plasmid overexpressing rsmA under the control of the gpdA promoter were assayed. (omicsdi.org)