Aspergillosis, Allergic Bronchopulmonary
Lung Diseases, Fungal
Invasive Pulmonary Aspergillosis
Gene Expression Regulation, Fungal
Drug Resistance, Fungal
Molecular Sequence Data
Microbial Sensitivity Tests
Amino Acid Sequence
Eye Infections, Fungal
Sequence Homology, Amino Acid
Drug Resistance, Multiple, Fungal
Sequence Analysis, DNA
Chromatography, Thin Layer
DNA, Ribosomal Spacer
Polymerase Chain Reaction
Granulomatous Disease, Chronic
Carboxylic Ester Hydrolases
Thaumatin production in Aspergillus awamori by use of expression cassettes with strong fungal promoters and high gene dosage. (1/1936)Four expression cassettes containing strong fungal promoters, a signal sequence for protein translocation, a KEX protease cleavage site, and a synthetic gene (tha) encoding the sweet protein thaumatin II were used to overexpress this protein in Aspergillus awamori lpr66, a PepA protease-deficient strain. The best expression results were obtained with the gdhA promoter of A. awamori or with the gpdA promoter of Aspergillus nidulans. There was good correlation of tha gene dosage, transcript levels, and thaumatin secretion. The thaumatin gene was expressed as a transcript of the expected size in each construction (1.9 or 1.4 kb), and the transcript levels and thaumatin production rate decayed at the end of the growth phase, except in the double transformant TB2b1-44-GD5, in which secretion of thaumatin continued until 96 h. The recombinant thaumatin secreted by a high-production transformant was purified to homogeneity, giving one major component and two minor components. In all cases, cleavage of the fused protein occurred at the KEX recognition sequence. This work provides new expression systems in A. awamori that result in very high levels of thaumatin production. (+info)
Identification and characterization of genes required for hyphal morphogenesis in the filamentous fungus Aspergillus nidulans. (2/1936)In the filamentous fungus Aspergillus nidulans, germination of an asexual conidiospore results in the formation of a hyphal cell. A key feature of spore germination is the switch from isotropic spore expansion to polarized apical growth. Here, temperature-sensitive mutations are used to characterize the roles of five genes (sepA, hypA, podB-podD) in the establishment and maintenance of hyphal polarity. Evidence that suggests that the hypA, podB, and sepA genes are required for multiple aspects of hyphal morphogenesis is presented. Notably, podB and sepA are needed for organization of the cytoskeleton at sites of polarized growth. In contrast, podC and podD encode proteins that appear to be specifically required for the establishment of hyphal polarity during spore germination. The role of sepA and the pod genes in controlling the spatial pattern of polarized morphogenesis in germinating spores is also described. Results obtained from these experiments indicate that the normal pattern of germ-tube emergence is dependent upon the integrity of the actin cytoskeleton. (+info)
Cloning and expression of a cDNA encoding the laccase from Schizophyllum commune. (3/1936)We cloned and analyzed the nucleotide sequence of a cDNA that encodes polyphenol oxidase (laccase) from the white-rot basidiomycete Schizophyllum commune. The nucleotide sequence of the full-length cDNA contained a 1554-base open reading frame that encoded a polypeptide of 518 amino acid residues, including a putative signal peptide of 16 residues. It contained four highly similar regions that are conserved in the deduced amino acid sequences of other laccases, including the region thought to be involved in copper binding. Aspergillus sojae strain 1860 (which has low protease levels) was transformed with the plasmid lacAL/pTPT, which contained the laccase gene under the control of the tannase promoter from Aspergillus oryzae. Laccase was secreted into the medium when transformants A1 and A2 were cultured in tannic acid-containing medium. (+info)
Purification and characterization of Aspergillus ficuum endoinulinase. (4/1936)Endoinulinase from Aspergillus ficuum, which catalyzes the hydrolysis of inulin via an endo-cleavage mode, was purified by chromatography from Novozym 230 as a starting commercial enzyme mixture on CM-Sephadex and DEAE-Sepharose, and by preparative electrophoresis under native conditions. The enzyme was estimated to be pure on the basis of its I/S ratio, whose value was infinite in our assay conditions. Two forms separated by using this method. SDS gel electrophoresis showed the two purified forms to respectively exhibit molecular weights of 64,000 +/- 500 and 66,000 +/- 1,000. The results of deglycosylation indicated that the two forms were originally the same protein but with different sugar contents. A molecular weight of 54,800 +/- 1,500 was found by gel filtration of the native enzyme, indicating the native functional protein to be a monomer. The enzyme showed nearly absolute substrate specificity towards inulin and inulooligosaccharides, and acted via an endo-attack to produce mainly inulotriose during the late stage of the reaction. The apparent Km and Vmax values for inulin hydrolysis were 8.1 +/- 1.0 mM and 773 +/- 60 U/mg, respectively. The internal peptides of the enzyme showed sequence homology to the endoinulinase of Penicillium purpurogenum. (+info)
Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. (5/1936)In mammals, the Rho family GTPase Rac2 is restricted in expression to hematopoietic cells, where it is coexpressed with Rac1. Rac2-deficient mice were created to define the physiological requirement for two near-identical Rac proteins in hematopoietic cells. rac2-/- neutrophils displayed significant defects in chemotaxis, in shear-dependent L-selectin-mediated capture on the endothelial substrate Glycam-1, and in both F-actin generation and p38 and, unexpectedly, p42/p44 MAP kinase activation induced by chemoattractants. Superoxide production by rac2-/- bone marrow neutrophils was significantly reduced compared to wild type, but it was normal in activated peritoneal exudate neutrophils. These defects were reflected in vivo by baseline neutrophilia, reduced inflammatory peritoneal exudate formation, and increased mortality when challenged with Aspergillus fumigatus. Rac2 is an essential regulator of multiple specialized neutrophil functions. (+info)
Production of specific monoclonal antibodies to Aspergillus species and their use in immunohistochemical identification of aspergillosis. (6/1936)Two anti-Aspergillus murine monoclonal antibodies (MAbs), designated 164G and 611F, have been produced; both specifically recognize cytoplasmic antigens of A. fumigatus, A. flavus, and A. niger by enzyme-linked immunosorbent assay. The MAbs can identify Aspergillus spp. both in frozen sections by immunofluorescence and in paraffin-embedded clinical specimens by immunofluorescence and immunoperoxidase staining. (+info)
Effect of zinc on adenine nucleotide pools in relation to aflatoxin biosynthesis in Aspergillus parasiticus. (7/1936)The adenylic acid systems of Aspergillus parasiticus were studied in zinc-replete and zinc-deficient media. The adenosine 5'-triphosphate levels of the fungus were high during exponential phase and low during stationary phase in zinc-replete cultures. On the other hand, the levels of adenosine 5'-diphosphate and adenosine 5'-monophosphate were low during exponential phase of growth and high during stationary phase. The adenosine 5'-triphosphate levels during exponential phase may indicate higher primary metabolic activity of the fungus. On the other hand, high adenosine 5'-monophosphate levels during stationary phase may inhibit lipid formation and may enhance aflatoxin levels. The inorganic phosphorus content was low in a zinc-replete medium throughout the growth period, thereby favoring aflatoxin biosynthesis. The energy charge during the exponential phase was high but low during the stationary phase. In general the energy charge values were lower because of high adenosine 5'-monophosphate content. (+info)
Characterization of the promoter for the gene encoding the aflatoxin biosynthetic pathway regulatory protein AFLR. (8/1936)Most genes in the aflatoxin biosynthetic pathway in Aspergillus parasiticus are regulated by the binuclear zinc cluster DNA-binding protein AFLR. The aflR promoter was analyzed in beta-glucuronidase reporter assays to elucidate some of the elements involved in the gene's transcription control. Truncation at 118 bp upstream of the translational start site increased promoter activity 5-fold, while truncation at -100 reduced activity about 20-fold. These findings indicate the presence of an important positive regulatory element between -100 and -118 and a negative regulatory region further upstream. Electrophoretic mobility shift assays on nuclear extracts from A. parasiticus induced for aflatoxin expression suggest that AFLR and another, possibly more abundant, protein bind to the -100/-118 region. Another protein binds to a sequence at position -159 to -164 that matches the consensus binding site for the transcription factor involved in pH-dependent gene regulation, PACC. (+info)
The symptoms of aspergillosis depend on the location and severity of the infection. In the lungs, it may cause coughing, fever, chest pain, and difficulty breathing. In the sinuses, it can cause headaches, facial pain, and nasal congestion. In the brain, it can cause seizures, confusion, and weakness.
Aspergillosis is typically diagnosed through a combination of imaging tests such as chest X-rays, CT scans, and MRI scans, along with a biopsy to confirm the presence of Aspergillus fungi.
Treatment of aspergillosis depends on the severity and location of the infection. In mild cases, treatment may involve antifungal medications and supportive care such as oxygen therapy and pain management. In severe cases, treatment may require hospitalization and intravenous antifungal medications.
Preventive measures for aspergillosis include avoiding exposure to dusty or damp environments, managing chronic conditions such as asthma and COPD, and taking antifungal medications as prescribed.
Aspergillosis can be a serious condition, especially in people with weakened immune systems, such as those with cancer, HIV/AIDS, or taking immunosuppressive drugs. In severe cases, aspergillosis can lead to life-threatening complications such as respiratory failure, sepsis, and organ damage.
In conclusion, aspergillosis is a common fungal infection that can affect various parts of the body, and it can be serious and potentially life-threatening, especially in people with weakened immune systems. Early diagnosis and appropriate treatment are essential to prevent complications and improve outcomes.
Pulmonary aspergillosis is a type of fungal infection that affects the lungs and is caused by the fungus Aspergillus. It can occur in people with weakened immune systems, such as those with cancer, HIV/AIDS, or taking immunosuppressive drugs following an organ transplant.
The symptoms of pulmonary aspergillosis can vary depending on the severity of the infection and may include:
* Coughing up blood or mucus
* Chest pain or tightness
* Shortness of breath
* Weight loss
In severe cases, pulmonary aspergillosis can lead to respiratory failure, which can be life-threatening.
Pulmonary aspergillosis is diagnosed through a combination of imaging tests such as chest X-rays, CT scans, and fungal cultures. Treatment typically involves antifungal medications and supportive care to manage symptoms and prevent complications. In severe cases, hospitalization may be necessary to provide oxygen therapy and other respiratory support.
Prevention is key in avoiding pulmonary aspergillosis, especially for individuals with weakened immune systems. This includes avoiding exposure to fungal spores, managing underlying health conditions, and taking antifungal medications as prescribed. Early diagnosis and treatment can significantly improve outcomes for those affected by this condition.
The main cause of ABPA is exposure to airborne spores of the fungus Aspergillus, which are commonly found in soil and decaying organic matter. Individuals with a pre-existing allergic condition may be more susceptible to developing an allergic reaction to these spores, leading to inflammation and damage to the airways.
Diagnosis of ABPA typically involves a combination of physical examination, medical history, and diagnostic tests such as chest X-rays, CT scans, and bronchoscopy with biopsy. Treatment for ABPA typically involves corticosteroids to reduce inflammation and antifungal medications to treat any underlying infection. In severe cases, hospitalization may be necessary to provide oxygen therapy and other supportive care.
Prevention of ABPA includes avoiding exposure to known allergens and maintaining good respiratory hygiene. This can involve regularly cleaning and disinfecting surfaces and objects, using HEPA filters in air purifiers, and wearing a mask when working with or around potentially contaminated materials.
Prognosis for ABPA is generally good if treated promptly and effectively, but untreated cases can lead to serious complications such as respiratory failure and other organ damage. With proper management and prevention strategies in place, individuals with ABPA can lead active and fulfilling lives.
Types of fungal lung diseases include:
1. Aspergillosis: This is an infection caused by the fungus Aspergillus, which is commonly found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with cancer, HIV/AIDS, or taking immunosuppressive drugs.
2. Cryptococcosis: This is an infection caused by the fungus Cryptococcus neoformans, which is found in soil and decaying wood. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
3. Histoplasmosis: This is an infection caused by the fungus Histoplasma capsulatum, which is found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
4. Pneumocystis pneumonia (PCP): This is an infection caused by the fungus Pneumocystis jirovecii, which is found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
5. Sporotrichosis: This is an infection caused by the fungus Sporothrix schenckii, which is found in soil and decaying organic matter. It can affect people with weakened immune systems, such as those with HIV/AIDS or taking immunosuppressive drugs.
Symptoms of fungal lung diseases can include:
* Chest pain
* Shortness of breath
Diagnosis of fungal lung diseases is typically made through a combination of physical examination, medical history, and laboratory tests such as chest X-rays, CT scans, and fungal cultures. Treatment usually involves antifungal medications and may also include supportive care to manage symptoms.
Prevention of fungal lung diseases includes:
1. Avoiding exposure to fungal spores by wearing protective clothing and gear when working with soil or decaying organic matter.
2. Maintaining good indoor air quality by using ventilation systems and reducing humidity.
3. Reducing the risk of infection by avoiding close contact with people who are at high risk of developing fungal lung diseases, such as those with weakened immune systems.
4. Avoiding smoking and other tobacco products, which can increase the risk of developing fungal lung diseases.
5. Managing underlying medical conditions, such as HIV/AIDS or taking immunosuppressive drugs, to reduce the risk of developing fungal lung diseases.
In IPA, the Aspergillus fungus invades the lungs and can cause inflammation, bleeding, and scarring. Symptoms include fever, cough, chest pain, and difficulty breathing. If left untreated, IPA can lead to respiratory failure and death.
IPA is diagnosed through a combination of imaging tests such as chest X-rays, CT scans, and bronchoscopy, as well as through laboratory tests that detect the presence of Aspergillus antigens or DNA in the body.
Treatment of IPA typically involves antifungal medications, such as voriconazole or caspofungin, which are given intravenously for several weeks. In severe cases, hospitalization and supportive care, such as oxygen therapy and mechanical ventilation, may be necessary.
Prevention of IPA is challenging, but efforts to reduce the risk include avoiding exposure to Aspergillus spores, managing underlying conditions that weaken the immune system, and promptly treating any respiratory infections that occur. Early detection and treatment of IPA can improve outcomes and reduce the risk of complications and death.
The most common types of mycoses include:
1. Ringworm: This is a common fungal infection that causes a ring-shaped rash on the skin. It can affect any part of the body, including the arms, legs, torso, and face.
2. Athlete's foot: This is a common fungal infection that affects the feet, causing itching, redness, and cracking of the skin.
3. Jock itch: This is a fungal infection that affects the groin area and inner thighs, causing itching, redness, and cracking of the skin.
4. Candidiasis: This is a fungal infection caused by Candida, a type of yeast. It can affect various parts of the body, including the mouth, throat, and vagina.
5. Aspergillosis: This is a serious fungal infection that can affect various parts of the body, including the lungs, sinuses, and brain.
Symptoms of mycoses can vary depending on the type of infection and the severity of the infection. Common symptoms include itching, redness, swelling, and cracking of the skin. Treatment for mycoses usually involves antifungal medications, which can be applied topically or taken orally. In severe cases, hospitalization may be necessary to monitor and treat the infection.
Preventive measures for mycoses include practicing good hygiene, avoiding sharing personal items such as towels and clothing, and using antifungal medications as prescribed by a healthcare professional. Early diagnosis and treatment of mycoses can help prevent complications and reduce the risk of transmission to others.
The symptoms of neuroaspergillosis can vary depending on the location and severity of the infection, but may include:
* Weakness or paralysis
* Vision problems
* Hearing loss
In severe cases, neuroaspergillosis can lead to brain abscesses, stroke, or death.
The diagnosis of neuroaspergillosis is based on a combination of clinical findings, laboratory tests, and imaging studies such as CT or MRI scans. Laboratory tests may include blood cultures, cerebrospinal fluid (CSF) analysis, and PCR testing for Aspergillus DNA.
Treatment of neuroaspergillosis typically involves a combination of antifungal medications and supportive care to manage symptoms and prevent complications. In some cases, surgical intervention may be necessary to drain abscesses or relieve pressure on the brain.
Prevention of neuroaspergillosis primarily involves managing underlying conditions that weaken the immune system, such as HIV/AIDS or cancer, and avoiding exposure to Aspergillus fungi. In high-risk individuals, prophylactic antifungal medications may be used to prevent infection.
There are several types of fungal eye infections, including:
1. Aspergillosis: This is a common type of fungal infection that affects the eye. It is caused by the fungus Aspergillus and can occur in people with weakened immune systems or pre-existing eye conditions.
2. Candidemia: This is another common type of fungal infection that affects the eye. It is caused by the fungus Candida and can occur in people with weakened immune systems or pre-existing eye conditions.
3. Cryptococcosis: This is a rare type of fungal infection that affects the eye. It is caused by the fungus Cryptococcus and can occur in people with weakened immune systems, such as those with HIV/AIDS.
4. Histoplasmosis: This is a rare type of fungal infection that affects the eye. It is caused by the fungus Histoplasma and can occur in people who have been exposed to the fungus in soil or bird droppings.
5. Blastomycosis: This is a rare type of fungal infection that affects the eye. It is caused by the fungus Blastomyces and can occur in people who have been exposed to the fungus in soil or water.
Fungal eye infections can cause a range of symptoms, including redness, discharge, pain, and vision loss. Treatment typically involves antifungal medication and may also include surgery to remove any infected tissue. In severe cases, fungal eye infections can lead to blindness if left untreated.
Prevention measures for fungal eye infections include good hygiene practices, such as washing hands regularly and avoiding close contact with people who have the infection. People with weakened immune systems should also avoid exposure to fungi by avoiding outdoor activities during peak fungal growth seasons and wearing protective clothing when working or playing in areas where fungi are likely to be present.
Overall, fungal eye infections are uncommon but can be serious conditions that require prompt medical attention. If you suspect you may have a fungal eye infection, it is important to seek medical care as soon as possible to receive proper diagnosis and treatment.
Examples of OIs include:
1. Pneumocystis pneumonia (PCP): A type of pneumonia caused by the fungus Pneumocystis jirovecii, which is commonly found in the lungs of individuals with HIV/AIDS.
2. Cryptococcosis: A fungal infection caused by Cryptococcus neoformans, which can affect various parts of the body, including the lungs, central nervous system, and skin.
3. Aspergillosis: A fungal infection caused by Aspergillus fungi, which can affect various parts of the body, including the lungs, sinuses, and brain.
4. Histoplasmosis: A fungal infection caused by Histoplasma capsulatum, which is commonly found in the soil and can cause respiratory and digestive problems.
5. Candidiasis: A fungal infection caused by Candida albicans, which can affect various parts of the body, including the skin, mouth, throat, and vagina.
6. Toxoplasmosis: A parasitic infection caused by Toxoplasma gondii, which can affect various parts of the body, including the brain, eyes, and lymph nodes.
7. Tuberculosis (TB): A bacterial infection caused by Mycobacterium tuberculosis, which primarily affects the lungs but can also affect other parts of the body.
8. Kaposi's sarcoma-associated herpesvirus (KSHV): A viral infection that can cause various types of cancer, including Kaposi's sarcoma, which is more common in individuals with compromised immunity.
The diagnosis and treatment of OIs depend on the specific type of infection and its severity. Treatment may involve antibiotics, antifungals, or other medications, as well as supportive care to manage symptoms and prevent complications. It is important for individuals with HIV/AIDS to receive prompt and appropriate treatment for OIs to help prevent the progression of their disease and improve their quality of life.
Also known as: chronic granulomatous disease, CGD.
1. Cutaneous fusariosis: This type of infection affects the skin and subcutaneous tissues, causing ulcers, nodules, and plaques.
2. Osteoarticular fusariosis: This type of infection affects the bones and joints, causing pain, swelling, and limited mobility.
3. Fusariosis sinusitis: This type of infection affects the paranasal sinuses and can cause chronic rhinosinusitis, meningitis, and ocular involvement.
4. Fusariosis pneumonia: This type of infection affects the lungs and can cause fever, cough, and difficulty breathing.
5. Fusariosis disseminated: This type of infection affects multiple organs and tissues, including the skin, bones, joints, lungs, and central nervous system.
The signs and symptoms of fusariosis can vary depending on the severity and location of the infection, but common symptoms include:
* Skin lesions such as ulcers, nodules, and plaques
* Joint pain and swelling
* Bone pain and limited mobility
* Difficulty breathing
* Weight loss
The diagnosis of fusariosis is based on a combination of clinical findings, laboratory tests, and imaging studies. Laboratory tests may include:
* Blood cultures: to isolate the fungus from the blood
* Skin or tissue biopsy: to confirm the presence of the fungus in the affected tissue
* Imaging studies such as X-rays, CT scans, or MRI scans: to evaluate the extent of the infection
Treatment of fusariosis is challenging and requires a multidisciplinary approach. The primary goal of treatment is to manage symptoms, prevent complications, and improve quality of life. Treatment options include:
* Antifungal medications: to target the fungus and prevent its growth
* Pain management: to control pain and discomfort
* Wound care: to promote healing of skin lesions and prevent further injury
* Physical therapy: to maintain joint mobility and strength
* Respiratory support: to manage respiratory symptoms
* Nutritional support: to ensure adequate nutrition and hydration
The prognosis for patients with fusariosis is generally poor, with high mortality rates reported in some cases. However, with early diagnosis, appropriate treatment, and close monitoring, some patients may experience improved symptoms and quality of life. It is important to note that the risk of recurrence is high in patients with fusariosis, and ongoing management and surveillance are often necessary to prevent further infections.
Prevention of fusariosis is challenging, but some measures can be taken to reduce the risk of infection. These include:
* Avoiding exposure to fungal spores
* Practicing good wound care and hygiene
* Avoiding immunosuppressive medications whenever possible
* Monitoring for signs of infection and seeking medical attention promptly if symptoms develop
Overall, fusariosis is a severe and potentially life-threatening infection that requires prompt diagnosis and appropriate treatment. With early intervention and ongoing management, some patients may experience improved outcomes and quality of life.
Antimicrobial-Resistant Aspergillus | Fungal Diseases | CDC
アミログルコシダーゼ from Aspergillus niger powder, white, ~120 U/mg | Sigma-Aldrich
Compost Is a Major Source of Pathogenic Aspergillus Spores | ASM.org
Quantitative iTRAQ Secretome Analysis of Aspergillus niger Reveals Novel Hydrolytic Enzymes
Aspergillosis: Diseases Caused By Aspergillus | Mold-Help.org - The world's largest TOXIC MOLD website
Genetic engineering in the <i>Aspergillus genus<...
Molecular cloning and biochemical characterization of an α-amylase family from Aspergillus niger | Wang | Electronic Journal of...
Contributions of Spore Secondary Metabolites to UV-C Protection and Virulence Vary in Different Aspergillus fumigatus Strains ...
Citric Acid Production by Wild and UV - Treated Strains of Aspergillus niger on Two Different Mineral Salt Media |...
Publication Year: 2020 / Subject: Aspergillus sojae and Plectranthus amboinicus - PubAg Search Results
Aspergillus Specific PCR and Galactomannan of Bronchoalveolar Lavage Are Superior to Concomitant Same-Day Testing of Concurrent...
CIPSM - AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus...
Effect of aspergillus infestation on nutritional value of chickpea seeds | International Journal of Current Research
Gene: ANIA 00859 - Summary - Aspergillus nidulans - Ensembl Genomes 56
Aspergillus niger CBS 147353
ASPERGILLUS | FUNGI | FLORAFONDNESS | 2023
aspergillus | Journey of Resilience
Aspergillus: Dangerous Mold on Plants
Species Report for: Aspergillus carbonarius
Aspergillus Oryzae Archives - Miracle Farms
Aspergillus fumigatus | primerdesign | genesig : genesig
Domain assignment for jgi|Aspca1|14395|e gw1.00168.488.1 from Aspergillus carbonarius ITEM 5010
Koji kin (aspergillus oryzae) « Shoku Japan
NHANES 2005-2006: Allergen Specific IgE(s) & Total IgE - Serum Data Documentation, Codebook, and Frequencies
- The natural lifestyle of Aspergillus niger made them more effective secretors of hydrolytic proteins and becomes critical when this species were exploited as hosts for the commercial secretion of heterologous proteins. (figshare.com)
- Microbial production of citric acid by a novel Aspergillus niger EE-12 and its UV - treated strain (UV-1) were carried out in shake flask cultures using mineral salt media containing sucrose or fructose as the carbon and energy sources. (nepjol.info)
- Aspergillus niger, A. flavus, A. quericinus, A. Oryzae, and A. nidulans are major Aspergillus species recovered from selected chickpea varieties. (journalcra.com)
- A. fumigatus, A. terreus, A. nidulans, A. flavus, and A. niger were inoculated on Czapek-Dox agar and grown Aspergillus fumigatus is a fungus with septate hyphae that branch at 45°, and conidia in radiating chains at ends of conidiophores. (web.app)
- The strains of aspergillus that pose the biggest threat to human health are Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, and Aspergillus terreus. (terravera.com)
- Organism-specific therapeutic regimens for otitis externa are provided below, including those for Pseudomonas aeruginosa, Staphylococcus aureus , Candida albicans , and Aspergillus niger . (medscape.com)
- Aspergillosis is an infection caused by Aspergillus , a common mold (a type of fungus) that lives indoors and outdoors. (cdc.gov)
- The genome size and the number of protein-coding genes are notably larger than those of the most common etiological agent of aspergillosis, Aspergillus fumigatus . (nih.gov)
- However, concentrations of Aspergillus spores have not been found to be correlated to any seasonal pattern or the occurrence of invasive aspergillosis (Hospenthal et al. (mold-help.org)
- The type of mold that causes most forms of aspergillosis, Aspergillus fumigatus, is common in our environment. (web.app)
- Aspergillosis precipitin is a laboratory test to detect antibodies in the blood resulting from exposure to the fungus aspergillus . (medlineplus.gov)
- For example, invasive aspergillosis often does not produce a positive result, even though aspergillus is present. (medlineplus.gov)
- Aspergillosis is a disease caused by a fungus (or mold) called Aspergillus. (nih.gov)
- Singh Shreya, Choudhary Hansraj, Agnihotri Sourav, Sehgal Inderpaul Singh, Agarwal Ritesh, Kaur Harsimran, Ghosh Anup, Chakrabarti Arunaloke, Rudramurthy Shivaprakash M.. LDBio Aspergillus immunochromatographic test lateral flow assay for IgG/IgM antibody detection in chronic pulmonary aspergillosis: Single-centre evaluation and meta-analysis. (who.int)
- Purpose: Chronic pulmonary aspergillosis (CPA) is an infection of the lung usually caused by Aspergillus fumigatus in patients with pre-existing pulmonary diseases. (who.int)
- This invention relates to assays for the detection and species-specific identification of Aspergillus fungi. (nih.gov)
- Det finns generellt 5 former av aspergillosEtiologiAspergillus fumigatus (vanligast), Aspergillus flavus (särskilt vid nedsatt immunförsvar 2007-11-01 17 hours ago 1999-04-01 Aspergillus fumigatus is the most common cause of human Aspergillus infections (both azole-resistant and nonresistant infections). (web.app)
- Aspergillus flavus. (web.app)
- MIXED ASPERGILLUS- aspergillus flavus var. (nih.gov)
- FAPP MIXTURE- aspergillus flavus var. (nih.gov)
- Most people breathe in Aspergillus spores every day without getting sick. (cdc.gov)
- It's difficult to avoid breathing in Aspergillus spores because the fungus is common in the environment. (mold-help.org)
- Because aspergillus grows so easily many people breathe airborne aspergillus spores regularly. (terravera.com)
- Some of the most harmful effects of aspergillus are caused when the spores are inhaled- this is a particular concern in the cannabis industry where the product is inhaled. (terravera.com)
- It is important to keep in mind that members of the genus Aspergillus are all free-living, saprobic species that can potentially become opportunistic pathogens (Bennett 2009). (mold-help.org)
- The cell wall integrity (CWI) pathway, best characterized in S. cerevisiae, is strikingly conserved in Aspergillus species. (cipsm.de)
- Major pathogenic species of Aspergillus. (web.app)
- Most of the species of Aspergillus are saprophytes growing on decaying vegetables. (florafondness.com)
- Some species of Aspergillus infect human ear and cause Otomycosis. (florafondness.com)
- The species of Aspergillus developing perfect stage i.e. cleistothecium are placed under the genus Eurotium. (florafondness.com)
- There are over 200 species of aspergillus, and they are very common. (terravera.com)
- Aspergillus species. (medlineplus.gov)
- Accurate clinical diagnosis of Aspergillus species has become increasingly important as certain species, such as A. terreus and A. fumigatus , are resistant to specific commonly employed antifungal compounds. (nih.gov)
- This invention directly addresses those inadequacies by providing a method to rapidly and accurately differentiate all medically important species of Aspergillus based on differences in the DNA sequences of the internal transcribed spacer 1 region of ribosomal DNA. (nih.gov)
- Asperterpenes A (1) and B (2), two 3,5-dimethylorsellinic acid-based meroterpenoids that contain a unique β-oriented Me-21 with an unprecedented 1,2,5-trimethyl-4,9-dioxobicyclo[3.3.1]non-2-ene-3-carboxylic acid moiety, were obtained from Aspergillus terreus in very limited amounts of 3.6 mg and 1.8 mg, respectively. (nih.gov)
- resistance in clinical Aspergillus isolates. (cdc.gov)
- A total of 3,788 Aspergillus isolates were screenedin22centersfrom19countries.Azole-resistant tries (18 European and 4 non-European sites) (Figure 1). (cdc.gov)
- Washington, D.C. - Fourteen percent of Aspergillus fumigatus isolates cultured from garden soils were resistant to an agricultural triazole antifungal drug, tebuconazole. (asm.org)
- Several isolates of the human pathogen Aspergillus fumigatus have been found contaminating the ISS, an environment with increased exposure to UV radiation. (caltech.edu)
- Taken together, this work suggests differential roles of specific spore metabolites across Aspergillus isolates and by types of environmental stress. (caltech.edu)
- Then it is also reasonable to conclude that management of Aspergillus and the disease-causing members of this genus will remain an important issue in the management of environmental and clinical health in the future. (mold-help.org)
- The annotated genome of Aspergillus tanneri , a recently discovered drug-resistant pathogen, was determined by employing the Oxford Nanopore MinION platform and the Funannotate pipeline. (nih.gov)
- Influence of Aspergillus fumigatus conidia viability on murine pulmonary microRNA and mRNA expression following subchronic inhalation exposure. (nih.gov)
- The types of health problems caused by Aspergillus include allergic reactions, lung infections, and infections in other organs. (cdc.gov)
- In addition, it has been associated with prolonged hospital stays , as well as several predisposing risk factors , such as fungal factors (nosocomial organism, the size of the conidia , and the ability of the Aspergillus spp. (bvsalud.org)
- The sample is sent to a laboratory where it is examined for precipitin bands that form when aspergillus antibodies are present. (medlineplus.gov)
- Aspergillus causes inflammation in the lungs and allergy symptoms such as coughing and wheezing, but doesn't cause an infection. (mold-help.org)
- Aspergillus causes inflammation in the sinuses and symptoms of a sinus infection (drainage, stuffiness, headache) but doesn't cause an infection. (mold-help.org)
- Aspergillus enters the body through a break in the skin (for example, after surgery or a burn wound) and causes infection, usually in people who have weakened immune systems. (mold-help.org)
- For people who have weakened immune systems, there may be some ways to lower the chances of developing a severe Aspergillus infection. (mold-help.org)
- A isolate, patient characteristics were registered through an zole resistance is increasingly recognized as a prob- online questionnaire, and patients with invasive aspergillo- lem in aspergillus diseases ( 1 ). (cdc.gov)
- To investigate azole resistance in clinical Aspergillus iso- lance Collaboration on Aspergillus Resistance in Europe lates, we conducted prospective multicenter international [SCARE-network]), comprising 22 centers from 19 coun- surveillance. (cdc.gov)
- As the name suggests, it is a ball of Aspergillus that grows in the lungs or sinuses, but usually does not spread to other parts of the body. (mold-help.org)
- Aspergillus can be grown on butter, bread, leather or any other similar substance in humid conditions. (florafondness.com)
- Grape, hops, and cannabis growers often have large amounts of plant material in one place, and aspergillus growth is always a risk. (terravera.com)
- Seeing product test positive for aspergillus can be crushing for growers. (terravera.com)
- A normal test result means you do not have aspergillus antibodies. (medlineplus.gov)
- Herein, we evaluated the performance of a newly introduced point of care test (POCT) kit, the LDBio Aspergillus IgG/IgM lateral flow assay (LFA) in India with the standard ImmunoCAP kit for diagnosing CPA. (who.int)
- Methods: A total of 60 serum samples (30 CPA cases and 30 controls) were evaluated by the Aspergillus immunochromatographic test (ICT) IgG/IgM LFA. (who.int)
- Many cannabis growers struggle with aspergillus, and some have had product recalls after their products hit the market. (terravera.com)
- Most people can easily avoid aspergillus in their homes by maintaining a clean kitchen and bathroom and keeping plumbing in good repair, but it can be more a difficult task in agricultural settings. (terravera.com)
- Aspergillus fumigatus up close. (nih.gov)
- I have helped a number of operators deal with their aspergillus problems. (terravera.com)