Substances which are of little or no nutritive value, but are used in the processing or storage of foods or animal feed, especially in the developed countries; includes ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS (both plain and LOCAL); VEHICLES; EXCIPIENTS and other similarly used substances. Many of the same substances are PHARMACEUTIC AIDS when added to pharmaceuticals rather than to foods.
United States Food and Drug Administration
Interaction of nucleotides with Asp(351) and the conserved phosphorylation loop of sarcoplasmic reticulum Ca(2+)-ATPase. (1/86)The nucleotide binding properties of mutants with alterations to Asp(351) and four of the other residues in the conserved phosphorylation loop, (351)DKTGTLT(357), of sarcoplasmic reticulum Ca(2+)-ATPase were investigated using an assay based on the 2', 3'-O-(2,4,6-trinitrophenyl)-8-azidoadenosine triphosphate (TNP-8N(3)-ATP) photolabeling of Lys(492) and competition with ATP. In selected cases where the competition assay showed extremely high affinity, ATP binding was also measured by a direct filtration assay. At pH 8.5 in the absence of Ca(2+), mutations removing the negative charge of Asp(351) (D351N, D351A, and D351T) produced pumps that bound MgTNP-8N(3)-ATP and MgATP with affinities 20-156-fold higher than wild type (K(D) as low as 0.006 microM), whereas the affinity of mutant D351E was comparable with wild type. Mutations K352R, K352Q, T355A, and T357A lowered the affinity for MgATP and MgTNP-8N(3)-ATP 2-1000- and 1-6-fold, respectively, and mutation L356T completely prevented photolabeling of Lys(492). In the absence of Ca(2+), mutants D351N and D351A exhibited the highest nucleotide affinities in the presence of Mg(2+) and at alkaline pH (E1 state). The affinity of mutant D351A for MgATP was extraordinarily high in the presence of Ca(2+) (K(D) = 0.001 microM), suggesting a transition state like configuration at the active site under these conditions. The mutants with reduced ATP affinity, as well as mutants D351N and D351A, exhibited reduced or zero CrATP-induced Ca(2+) occlusion due to defective CrATP binding. (+info)
On the sweetness of N-(trifluoroacetyl)aspartame. (2/86)A panel of tasters has found that the N-trifluoroacetyl derivative of aspartame is five times less sweet than the parent compound, contrary to the tenet in the literature, but consistent with sweet receptor models which require this nitrogen to exist in protonated form. (+info)
Genetic taste responses to 6-n-propylthiouracil among adults: a screening tool for epidemiological studies. (3/86)Genetically mediated taste responsiveness to 6-n-propylthiouracil (PROP) has been linked to reduced acceptance of some bitter foods. In this community-based study male (n = 364) and female (n = 378) adults enrolled in a self-help dietary intervention trial were screened for PROP taster status. Respondents, aged 18--70 years, were mailed filter papers impregnated with PROP or with aspartame solutions. They received instructions to rate taste intensity and hedonic preference using nine point category scales. Women rated PROP as more bitter than did men. Both sweetness and bitterness ratings were lower for older adults. Taste responsiveness to PROP was unrelated to body mass index in women or men. Higher bitterness ratings for PROP were weakly associated with higher sweetness ratings for aspartame, but were unrelated to sweet taste preferences. Successful administration of PROP filter papers by mail suggests new avenues for the screening of taste phenotypes in epidemiological studies. (+info)
Whole nerve chorda tympani responses to sweeteners in C57BL/6ByJ and 129P3/J mice. (4/86)The C57BL/6ByJ (B6) strain of mice exhibits higher preferences than does the 129P3/J (129) strain for a variety of sweet tasting compounds. We measured gustatory afferent responses of the whole chorda tympani nerve in these two strains using a broad array of sweeteners and other taste stimuli. Neural responses were greater in B6 than in 129 mice to the sugars sucrose and maltose, the polyol D-sorbitol and the non-caloric sweeteners Na saccharin, acesulfame-K, SC-45647 and sucralose. Lower neural response thresholds were also observed in the B6 strain for most of these stimuli. The strains did not differ in their neural responses to amino acids that are thought to taste sweet to mice, with the exception of L-proline, which evoked larger responses in the B6 strain. Aspartame and thaumatin, which taste sweet to humans but are not strongly preferred by B6 or 129 mice, did not evoke neural responses that exceeded threshold in either strain. The strains generally did not differ in their neural responses to NaCl, quinine and HCl. Thus, variation between the B6 and 129 strains in the peripheral gustatory system may contribute to differences in their consumption of many sweeteners. (+info)
Application of the U and gamma' models in binary sweet taste mixtures. (5/86)The U and Gamma' models of sensory interactions, successfully applied in olfaction for several years, are tested here using data from published studies on sweetness. The models are subsequently tested on new data obtained in studies of binary mixtures of four sodium sulfamates. The U model allows for the estimation of a global interaction, whereas the Gamma' model allows for the distinction between that which is due to an intrinsic interaction in the mixture itself and that which may be due to the power function exponents in the mixture. The models give satisfactory predictions for observed phenomena of sweet taste suppression, synergism or pure additivity. Additionally, they appear to be more suitable than other models recently applied in taste, particularly the equiratio model. Application of the models to the sulfamate mixtures, reveals additivity for sodium cyclohexylsulfamate (cyclamate)/potassium cyclohexylsulfamate and sodium cyclohexylsulfamate/sodium exo-2-norbornylsulfamate, respectively; whereas for sodium cyclohexylsulfamate/sodium 3-bromophenylsulfamate, the models revealed a slight hypo addition which is simply due to the dissimilarity values of the power function exponents of the components. (+info)
The effect of various substances on the suppression of the bitterness of quinine-human gustatory sensation, binding, and taste sensor studies. (6/86)The purpose of this study was to quantify the degree of suppression of the perceived bitterness of quinine by various substances and to examine the mechanism of bitterness suppression. The following compounds were tested for their ability to suppress bitterness: sucrose, a natural sweetener; aspartame, a noncaloric sweetener; sodium chloride (NaCl) as the electrolyte; phosphatidic acid, a commercial bitterness suppression agent; and tannic acid, a component of green tea. These substances were examined in a gustatory sensation test in human volunteers, a binding study, and using an artificial taste sensor. Sucrose, aspartame, and NaCl were effective in suppressing bitterness, although at comparatively high concentrations. An almost 80% inhibition of bitterness (calculated as concentration %) of a 0.1 mM quinine hydrochloride solution required 800 mM of sucrose, 8 mM of aspartame, and 300 mM NaCl. Similar levels of bitterness inhibition by phosphatidic acid and tannic acid (81.7, 61.0%, respectively) were obtained at much lower concentrations (1.0 (w/v)% for phosphatidic acid and 0.05 (w/v)% for tannic acid). The mechanism of the bitterness-depressing effect of phosphatidic acid and tannic acid was investigated in terms of adsorption and masking at the receptor site. With phosphatidic acid, 36.1% of the bitterness-depressing effect was found to be due to adsorption, while 45.6% was due to suppression at the receptor site. In the case of 0.05 (w/v)% tannic acid, the total bitterness-masking effect was 61.0%. The contribution of the adsorption effect was about 27.5% while the residual masking effect at the receptor site was almost 33%. Further addition of tannic acid (0.15 (w/v)%), however, increased the bitterness score of quinine, which probably represents an effect of the astringency of tannic acid itself. Finally, an artificial taste sensor was used to evaluate or predict the bitterness-depressing effect. The sensor output profile was shown to reflect the depressant effect at the receptor site rather well. Therefore, the taste sensor is potentially useful for predicting the effectiveness of bitterness-depressant substances. (+info)
Formaldehyde-induced shrinkage of rat thymocytes. (7/86)To test the possibility that micromolar formaldehyde, a metabolite of methanol derived from aspartame, exerts cytotoxicity, its effect on rat thymocytes was examined under the in vitro condition using a flow cytometer. Incubation of thymocytes with formaldehyde at 100 micro M or more for 24 h significantly increased the populations of shrunken cells and cells with hypodiploid DNA. The peak blood concentration of methanol in human subjects administered abuse doses of aspartame has been reported to exceed 2 mg/dL (625 micro M). It would increase the population of thymocytes undergoing apoptosis if formaldehyde at 100 micro M or more appears in the blood after administration of aspartame. (+info)
Modified DNA aptamers against sweet agent aspartame. (8/86)We obtained a modified DNA aptamer against sweetener, aspartame, by in vitro selection method. The modified DNA was prepared from dATP, dGTP, dCTP and a modified dTTP bearing a terminal amino group at C-5 position in place of thymidine by PCR using a hyper thermophilic DNA polymerase, KOD Dash DNA polymerase. The synthetic 102-mer DNA with a 60-mer random region was used as an initial template for the PCR. The PCR-amplified modified DNA library was applied to an aspartame-agarose column, and then the bound modified DNA was eluted from the column for the affinity chromatography selection. Repeating the procedure, we selected the modified DNA aptamer against aspartame. (+info)
... foods that contain aspartame are required to list aspartame among the ingredients, include the amount of aspartame per serving ... Aspartame is not recognized by rodents due to differences in the taste receptors. Aspartame is rapidly hydrolyzed in the small ... Aspartame is around 180 to 200 times sweeter than sucrose (table sugar). Due to this property, even though aspartame produces 4 ... The PBOI concluded aspartame does not cause brain damage, but it recommended against approving aspartame at that time, citing ...
FDA Statement on Aspartame, November 18, 1996 "Aspartame - what it is and why it's used in our food". Food Standards Australia ... The controversy over aspartame safety originated in perceived irregularities in the aspartame approval process during the 1970s ... "EFSA makes aspartame studies available". Food Navigator. 2011. Retrieved November 25, 2011. "EFSA delay Aspartame review ... In December 1975, the FDA placed a stay on the aspartame approval, preventing Searle from marketing aspartame.: 28 The Searle ...
The rights to aspartame-acesulfame are now owned by The NutraSweet Company Inc who have continued to market the sweetener ... Aspartame-acesulfame salt is an artificial sweetener marketed under the name Twinsweet. It is produced by soaking a 2-1 mixture ... Aspartame-acesulfame salt was invented in 1995 by sweetener expert Dr John Fry while working for The Holland Sweetener Company ... In North America it falls under the same regulations as aspartame and acesulfame-K, and is also approved for use in China, ...
... foods containing aspartame must carry ingredient panels that refer to the presence of "aspartame or E951" and they must be ... ISBN 1-57259-153-6. "Aspartame". UK: Food Standards Agency. Archived from the original on 2012-02-21. Retrieved 2007-06-19. "D- ... Another common source of phenylalanine is anything sweetened with the artificial sweetener aspartame, such as diet drinks, diet ... Accordingly, all products in Australia, the U.S. and Canada that contain aspartame must be labeled: "Phenylketonurics: Contains ...
"Aspartame". UK FSA. 17 June 2008. Retrieved 23 September 2010. "Aspartame". EFSA. Retrieved 23 September 2010. "Aspartame". ... When cooked or stored at high temperatures, aspartame breaks down into its constituent amino acids. This makes aspartame ... with aspartame being one of the most rigorously tested food ingredients to date. Although aspartame has been subject to claims ... Aspartame was discovered in 1965 by James M. Schlatter at the G.D. Searle company. He was working on an anti-ulcer drug and ...
"Aspartame". UK FSA. June 17, 2008. Retrieved April 20, 2011. "Aspartame". EFSA. Retrieved April 20, 2011. "Aspartame". Health ... "Food Additive Approval Process Followed for Aspartame". Food Additive Approval Process Followed for Aspartame GAO/HRD-87-46 ( ... aspartame, which was marketed as the brand NutraSweet, in 1983. Aspartame has been the subject of controversy, most notably in ... Aspartame has been deemed safe for human consumption by regulatory agencies in their respective countries, including the U.S. ...
List of health scares
Hattan, David (2 February 2010). "Aspartame". Snopes. Retrieved 25 March 2014. "The Mouse that Roared: Health Scares on the ... and statements about the toxicity of methanol produced by aspartame metabolism rely on ignoring the small amounts produced by ... In 1998 an email began circulating claiming that aspartame, an artificial sweetener, caused many chronic diseases, including ...
uses the slogan "Kick Aspartame" to promote their sugar-free and aspartame-free products. In 2010, entrepreneur Jay Klein aimed ... PUR Gum is a brand of aspartame-free gum produced by The PUR Company Inc. and founded in 2010 by Jay Klein in Toronto, Ontario ... "Aspartame-free gum makes inroads in first year". The Canadian Jewish News. 2011-11-17. Retrieved 2014-06-27. Blackwell, Richard ... Watson, Elaine (2013-08-19). "Kicking aspartame? The rise and rise of PÜR Gum". FoodNavigator USA. Retrieved 2014-06-27. Seale ...
Sprite Zero Sugar
... aspartame, and acesulfame potassium. (Aspartame contains phenylalanine.) Comparing Sprite Zero Sugar to other popular lemon- ...
Aspartame Petersen S; Muller E (1948). "Über eine neue Gruppe von Süsstoffen (On a new group of sweet substances)". Chemische ...
The sweetener aspartame, present in many diet foods and soft drinks, must also be avoided, as aspartame contains phenylalanine ... 172.804 Aspartame". US Food and Drug Administration. 1 April 2018. Retrieved 22 August 2019. MacDonald A, Rylance GW, Asplin D ...
Cook, Winifred I. (1983-05-31). "Aspartame is being used". The Central New Jersey Home News. p. 4. Retrieved 2020-09-25. ... Crystal Light is sweetened with a combination of aspartame, acesulfame potassium, Sucralose, and/or sugar depending on the ...
He was involved in the evaluations of aspartame when it was first being introduced as an artificial sweetener; he initially ... Rovner, Sandy (1 July 1983). "Aspartame: Sweet and Sour". Washington Post. "Hormone Pills Aid Sleep". The New York Times. ...
Aspartame has been deemed safe for human consumption by the regulatory agencies of many countries. Diet Coke and Mentos ... "Coke Beginning Aspartame Use". New York Times. August 18, 1983. p. D4. Ordoñez, Franco (March 3, 2005). "Suit Alleges Deceit in ... Diet Coke in the US was sweetened with aspartame, an artificial sweetener, after the sweetener became available in the United ... After Diet Rite cola advertised its 100 percent use of aspartame, and the manufacturer of NutraSweet (then G. D. Searle & ...
Timeline of United States discoveries
1965 Aspartame Aspartame is the name for an artificial, non-saccharide sweetener, aspartyl-phenylalanine-1-methyl ester; that ... Aspartame was discovered in 1965 by James M. Schlatter, a chemist working for G.D. Searle & Company. Schlatter had synthesized ... "Desert Island Discs". BBC Radio 4. "History". The Aspartame Information Service. Landolt, Arlo U. (1968). "A New Short-Period ... aspartame in the course of producing an anti-ulcer drug candidate. 1965 Pulsating white dwarfs A pulsating white dwarf is a ...
solesides26 (20 June 2012). "Aspartame Skate Video" (Video upload). YouTube. Google, Inc. Retrieved 14 January 2013.[dead ... Aspartame Lakai: Beware Of The Flare (2002) Cliche: Gypsy Tour (2004) Cliche: Bon Appetit (2004) Cliche: Freedom Fries (2004) ...
New York University Tandon School of Engineering
... oversaw the development of the artificial sweetener aspartame; developed nontoxic processes to create food colorings and remove ... development of the artificial sweetener aspartame; development of nontoxic processes to create food colorings and remove ...
Other examples include aspartame and carnosine. Diborane (B2H6) is a classic example of an inorganic dimer. Borane does not ...
The stereochemistry of aspartame is conserved during the synthesis and therefore, neotame and aspartame have the same ... Aspartame binds to the same receptor. Water solutions of neotame, that are equivalent in sweetness to sucrose water solutions, ... Unlike aspartame, neotame doesn't form diketopiperazines via intra-molecular cyclization due to its N-alkyl substitution with 3 ... Neotame, also known by the trade name Newtame, is a non-caloric artificial sweetener and aspartame analog by NutraSweet. By ...
Median lethal dose
"Material Safety Data Sheet: Aspartame" (PDF). Spectrum. Archived from the original (PDF) on 2016-12-26. "Safety (MSDS) data for ...
In that same year, aspartame was discovered. Aspartame was introduced into the Assugrin brand as Assugrin Gold. In 1987, orange ...
Pepsi Zero Sugar
"Pepsi Reintroducing Aspartame, Bringing Back Crystal Pepsi". "Diet Pepsi Max". "DIET PEPSI MAX SAYS "WAKE UP, PEOPLE!"appeared ... Zero calories." Carbonated water Caramel color Phosphoric acid Aspartame Potassium benzoate Caffeine Natural flavor Acesulfame ... ginseng-infused cola sweetened with aspartame and acesulfame K, marketed by PepsiCo. It has nearly twice the caffeine of ...
Following the US FDA's re-approval of aspartame in 1981, Ajinomoto began producing the sweetener at its Tokai factory in 1982. ... "Court of Appeal rules in Ajinomoto/Asda aspartame case". www.foodbev.com. 2010-06-03. Retrieved 2010-06-23. "Radical new twist ... entered the sweetener business by producing aspartame. In 1984 it released a low-calorie consumer sweetener PAL SWEET. By 2021 ... is the world's largest manufacturer of aspartame, sold under the trade name Aminosweet. Ajinomoto also sells ...
Aspartame Aspartame controversy Sugar substitute "Canderel - for a Healthy Balanced Lifestyle that Tastes as Good as Sugar. ... Canderel is a brand of artificial sweetener made mainly from aspartame. Canderel is marketed by The Merisant Company, a global ... It is the leading aspartame-based sweetener in France (where it was launched in 1979) and the United Kingdom (since 1983). ... "Canderel tablets" ingredients: lactose, aspartame, acesulfame potassium, leucine, cross-linked CMC, flavouring. Canderel is ...
... the artificial sweetener aspartame has two enantiomers. L-aspartame tastes sweet whereas D-aspartame is tasteless. Odor: R-(-)- ...
Scarlett Johansson on screen and stage
Bradshaw, Peter (April 20, 2016). "Captain America: Civil War review - an aspartame rush". The Guardian. Archived from the ...
Bradshaw, Peter (19 April 2016). "Captain America: Civil War review - an aspartame rush". The Guardian. Archived from the ...
Aspartame was also discovered accidentally when chemist Schlatter tasted a sweet substance that had stuck to his hand. ... Gratzer, Walter (28 November 2002). "5. Light on sweetness: the discovery of aspartame". Eurekas and Euphorias: The Oxford Book ...
Diet Mountain Dew
In 2006 Diet Mountain Dew was reformulated with a new "Tuned Up Taste", using a blend of sucralose, aspartame, and acesulfame ... The previous formulation was sweetened exclusively with aspartame. Smith, Andrew (2006). Encyclopedia of junk food and fast ...
In 2015, Nooyi removed aspartame from Diet Pepsi. As part of Performance with a Purpose, Nooyi also focused on environmental ...
Evaluation of Consumer Complaints Related to Aspartame Use
FDA had received about consumption of aspartame-containing products. The request followed an increase in aspartame-related ... aspartame and onset of symptoms often were incomplete because aspartame consumption was part of the daily routine. ... where the possibility of aspartame use leading to illness received particularly extensive press coverage. Although aspartame- ... As far as is known, complaints, such as those reported in this analysis as being related to aspartame use, have not been ...
Breaking News -- $350 Million RICO Lawsuit Filed Over Aspartame
Defendants in this lawsuit continue to maintain that aspartame is safe for consumption. Aspartame is found in more than 5,000 ... 350 MILLION RICO LAWSUIT FILED OVER ASPARTAME By Devvy. Posted: September 16, 2004. 12:05 AM Eastern. NewsWithViews.com A $350 ... Yet, the false results were submitted to the FDA like the rest of the 150 G.D. Searle studies (on aspartame and other products ... Plaintiffs maintain that this lawsuit will prove how deadly the chemical sweetener aspartame is when consumed by humans. ...
Aspartame - PubMed
An extremely large intake of aspartame (equivalent to 17 cans of soda or 100 packets of Equal Sweetener) can slightly increase ... Aspartame is not detectable in breastmilk after maternal ingestion because it is rapidly broken down in the mothers body. ... Aspartame No authors listed In: Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child ... Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut. Burgert SL, Andersen DW ...
Profile for satire writer Aspartame Boy | The Spoof
Aspartame sources, health risks
Aspartame is a man-made sweetener with almost no calories that is used in place of sugar. It is a compound ... ... Aspartame creates depression and exacerbates anxiety - heres how. Summary. Aspartame is a man-made sweetener used to replace ... Harmful effects that can be caused by aspartame. Only a very small amount of aspartame is needed to give food and beverages a ... Aspartame withdrawal and side effects explained - Heres how to protect yourself. *Aspartame found to cause breast cancer, ...
Aspartame doesn't raise risk of cancer - DVHARDWARE
"It goes a fair way toward allaying concerns about aspartame," said Michael Jacobson, head of the Center for Science in the ... Aspartame doesnt raise risk of cancer. Posted on Thursday, April 06 2006 @ 11:16 CEST by Thomas De Maesschalck ... A huge study involving 340,045 men and 226,945 women, ages 50 to 69, found that the artificial sweetener aspartame doesnt ... but according to the study this is false as aspartame, which replaces sugar, doesnt have nasty side-effects. No increased risk ...
Bread - Aspartame
DailyMed - LIPOTOX- squalene, cholesterinum, estrogen, progesterone, aspartame, benzalkonium chloride, formalinum, methylene...
ASPARTAME (UNII: Z0H242BBR1) (ASPARTAME - UNII:Z0H242BBR1) ASPARTAME. 30 [hp_X] in 1 mL. ... squalene, cholesterinum, estrogen, progesterone, aspartame, benzalkonium chloride, formalinum, methylene chloride liquid. ... Squalene 8X, Cholesterinum 12X, Estrogen 12X, Progesterone 12X, Aspartame 30X, Benzalkonium chloride 30X, Formalinum 30X, ... Label: LIPOTOX- squalene, cholesterinum, estrogen, progesterone, aspartame, benzalkonium chloride, formalinum, methylene ...
ASPARTAME STUDY - UK
Ralph Walton who has also done a study on aspartame said, the correct ADI for aspartame is zero. The independent aspartame ... Subject: Aspartame Study. UK. Hi All,. I was sent this email the other day. Professor Atkin is doing a study on Aspartame and ... These are not experts that are with the aspartame industry who defend aspartame and create the propaganda. These are ... aspartame in people who say they have a problem eating aspartame and people who normally consume foods containing aspartame ...
Revisiting the safety of aspartame - PubMed
Since 1981, when aspartame was first approved by the US Food and Drug Administration, researchers have debated both its ... Aspartame is a synthetic dipeptide artificial sweetener, frequently used in foods, medications, and beverages, notably ... Aspartame Safety as a Food Sweetener and Related Health Hazards. Shaher SAA, Mihailescu DF, Amuzescu B. Shaher SAA, et al. ... Aspartame. Review of safety issues. Council on Scientific Affairs. [No authors listed] [No authors listed] JAMA. 1985 Jul 19; ...
Is Aspartame Bad for You?
Weve all heard the rumors about aspartame, but is it really that bad for you? ... Is aspartame good for you?. Despite all the negatives, aspartame isnt all that bad. According to Diabetes.co.uk, aspartames ... What is aspartame?. According to EcoWatch, aspartame mimics sugar in the mouth by stimulating the sweet taste buds on the ... Is aspartame bad for you?. According to MedicineNet, aspartame has been linked to everything from pancreatic damage to cancer, ...
Aspartame Can Harm Your Health
Aspartame: New Study Renews Cancer Concern, Says CSPI | Center for Science in the Public Interest
The smallest amount of aspartame (20 milligrams per kilogram of body weight) that caused a significant increase in cancer ... Aspartame, also sold as Equal and NutraSweet, is used in Diet Coke, Diet Pepsi, and thousands of other foods and is consumed by ... The authors of the Italian study call for "urgent re-examination of permissible exposure levels of [aspartame] in both food and ... CSPI has long urged that aspartame be better tested, but has not maintained that the artificial sweetener is harmful, except to ...
Aaren San - Aspartame - Plasmapool
Diet Pepsi Is Removing Aspartame From Its Product In Stores, But Not Online
PepsiCo has decided to replace the aspartame in Diet Pepsi with sucralose. ... and about three times as sweet as aspartame. Sucralose has received slightly less public contempt than aspartame, though both ... Diet Pepsi Is Removing Aspartame From Its Product In Stores, But Not Online. Jul 10, 2015 10:39 AM. By Ali Venosa ... Aspartame was discovered in 1965 and approved for use in carbonated beverages in 1983 by the Food and Drug Administration (FDA ...
How to Detox From Aspartame and Other Artificial Sweeteners
Detoxing from Aspartame, an artificial sweetener, includes activated charcoal to remove toxicity from the body. Supplements can ... Side Effects of Aspartame Toxicity. Being that aspartame is a sugar alternative designed to be safe and present in so many ... Detoxing Aspartame. Whether experiencing those effects or not, you should consider detoxing your body from aspartame to prevent ... The issue is not the toxicity of aspartame that kills us. It is the resultant breakdown of aspartame by our own body to form ...
Monsanto's Saccharin + Aspartame + GMO - Janet Starr Hull PhD, CN
Filed Under: Aspartame Tagged With: aspartame, diet sweeteners, GD Searle, GMO, GMO foods, GMO seeds, GMOs, history of ... The Aspartame Matrix. Monsanto is all over the news these days as the target of the hot debate concerning GMO health safety. I ... Monsantos Saccharin + Aspartame + GMO. July 15, 2013. By Janet Hull PhD, CN ... Yep - Monsanto owned and produced BOTH saccharin and NutraSweet/Equal (aspartame), at the same time, over several decades. ...
New aspartame distribution tie-up for UK focused on security of supply
A new aspartame distribution deal will benefit the UK and Irish food and drink sector through security of supply, claims ... Sweet UK deal for ACT on aspartame A new aspartame distribution deal will benefit the UK and Irish food and drink sector ... Aspartame demand . According to Leatherhead, aspartame remains one of the most widely used and widely recognised of the ... Aspartame safety . Leatherhead further notes that negative publicity linking aspartame consumption with cancer has also ...
Inquiry for ASPARTAME 22839-47-0 of China ASPARTAME 22839-47-0 Suppliers
Aspartame | Running Raw
How Many Calories in Gelatin desserts, dry mix, reduced calorie, with aspartame, no added sodium
... with aspartame, no added sodium along with its full nutrition facts including carbs, fat, protein and more. ... How many calories are there in Gelatin desserts, dry mix, reduced calorie, with aspartame, no added sodium?. Here you will find ... the full nutrition facts for Gelatin desserts, dry mix, reduced calorie, with aspartame, no added sodium including calories, ...
Lemonade, low calorie, with aspartame, powder, prepared with water nutrition
... with aspartame, powder, prepared with water. Daily value nutrient chart. ... Lemonade, low calorie, with aspartame, powder, prepared with water. Log in to save to My Foods. *1 serving 1 cup 8 fl oz (239g) ... Nutrition information for Lemonade, low calorie, with aspartame, powder, prepared with water. The nutrition information on this ... Nutrition information for Lemonade, low calorie, with aspartame, powder, prepared with water. The nutrition information on this ...
Organics, River Conservation, GE Free, Human Rights & the Dangers of Aspartame - Prism News Podcast » Prism Webcast News
Additive 951/aspartame is technically defined as L-Aspartyl-l-phenylalanine methyl ester, 98%, aspartame CAS #22839-47-0, ... The Dangers of Aspartame by Dr Betty Martini. The New Zealand Soil & Health Association and the Safe Food Campaign recently ... In this podcast I interview Betty Martini about the dangers of aspartame, but first I needed to find out how to pronounce it ... Organics, River Conservation, GE Free, Human Rights & the Dangers of Aspartame - Prism News Podcast. Sunday, August 12, 2007. ...
Aspartame hazard and risk assessment results released. Aspartame results Home Assessments of the health impacts of the non- ... Joint summary of findings of the evaluation of aspartame. Read Summary of findings: English, French, Arabic, Chinese, Russian, ... sugar sweetener aspartame are released today by the International Agency for Research on Cancer (IARC) and the World Health ... IARC classified aspartame as possibly carcinogenic to humans (IARC Group 2B) and JECFA reaffirmed the acceptable daily intake ...
aspartame - NIH Director's Blog
aspartame. Taking a New Look at Artificial Sweeteners Posted on October 7th, 2014. by Dr. Francis Collins ... Tags: antibiotics, artificial sweeteners, aspartame, blood glucose level, calories, DNA sequencing, glucose, glucose ... or aspartame (Equal®, Nutrasweet®). Both groups ate a diet of normal mouse chow. ...
Aspartame | Sherein Saeid Abdelgayed
Zero calorie sweetener with aspartame by CHESTNUT HILL nutrition facts and analysis.
️ Zero calorie sweetener with aspartame by CHESTNUT HILL nutrition facts and analysis. ... Zero calorie sweetener with aspartame by CHESTNUT HILL nutrition facts and analysis.. Daily values are based on a 2000 calorie ... Zero calorie sweetener with aspartame by CHESTNUT HILL belong to Granulated, Brown & Powdered Sugar food category. The UPC ... Zero calorie sweetener with aspartame by CHESTNUT HILL nutrition facts and analysis per 1 packet (1.0 g). ...
SweetenersSaccharinNutraSweetAcesulfame potassiumToxicity Evaluation of AspartameContinued aspartame consumptionConsumptionArtificialApproval of aspartameSweetener aspartameRatsCarcinogenicitySodiumMimicsEvaluationEqualIngestionCarcinogenicDietExposureMice1983FormaldehydeNutritionBeveragesStudiesAllergiesHealthResearchersSugarEquivalentHarmfulCommonlySymptomsDangerousCancerChemicalStudyDeclineGroupBodyNewsSafeFoodMedicationsSmallIndustryAnimalsSearchSide
- For example, those who suffer from diabetes often opt for alternative sweeteners to keep their blood sugar down, but because aspartame interferes with one's metabolism to a degree, it can trigger a condition called metabolic syndrome. (greenmatters.com)
- At a minimum, the government should conduct new animal studies of aspartame and encourage consumers and manufacturers that use artificial sweeteners to switch to sucralose, which CSPI considers to be the safest of the several artificial sweeteners on the market. (cspinet.org)
- According to Leatherhead, aspartame remains one of the most widely used and widely recognised of the intense sweeteners, mainly as a result of its strong position in the US, which accounts for 60% of global demand. (bakeryandsnacks.com)
- Recent years have seen an increase in consumption of diet and light foods by teenagers or those who are looking for a low-calorie diet , thus resulting in several sweeteners such as aspartame . (bvsalud.org)
- Nonnutritive sweeteners (NNS), including saccharin, sucralose, aspartame, and acesulfame-potassium, are commonly consumed in the general population, and all except for saccharin are considered safe for use during pregnancy and lactation. (nih.gov)
- 1. Genotoxicity testing of low-calorie sweeteners: aspartame, acesulfame-K, and saccharin. (nih.gov)
- 8. Estimated intake of the artificial sweeteners acesulfame-K, aspartame, cyclamate and saccharin in a group of Swedish diabetics. (nih.gov)
- Yep - Monsanto owned and produced BOTH saccharin and NutraSweet/Equal (aspartame), at the same time, over several decades. (janethull.com)
- The aim of the this study was to evaluate the effect of an intensive treatment with chlorhexidine (CHX) gel, containing either saccharin or aspartame, in deaf children highly infected with mutans streptococci (MS). Methods: Eighteen children were randomly divided into two groups, according to the sweetener used to improve the CHX gel bitter taste: saccharin or aspartame. (bvsalud.org)
- 5. Intake of saccharin, aspartame, acesulfame K and cyclamate in Italian teenagers: present levels and projections. (nih.gov)
- 17. Assessment of Korean consumer exposure to sodium saccharin, aspartame and stevioside. (nih.gov)
- Aspartame might be most recognizable as the main sweetening component of Nutrasweet, Equal, and Sugar Twin. (greenmatters.com)
- However, they blew it this time with their editorial on aspartame (NutraSweet) that was published yesterday. (mercola.com)
- Aspartame, also sold as Equal and NutraSweet, is used in Diet Coke, Diet Pepsi, and thousands of other foods and is consumed by 200 million people in the United States and around the world, according to the industry's Calorie Control Council. (cspinet.org)
- With the recent upturn in health concerns, aspartame has been and continues to be, used in many products, including many trademark brands: Tropicana Slim, NutraSweet, Equal, diet sodas, condiments, and even some vitamin supplements. (earthclinic.com)
- In 1982 , Rumsfeld had succeeded in getting the U.S. Food and Drug Administration to finally approve NutraSweet (aspartame), which had previously been denied FDA approval, and engineered Monsanto's purchase of GD Searle in 1985. (janethull.com)
- 12. Astrogliosis and decreased neural viability as consequences of early consumption of aspartame and acesulfame potassium in male Wistar rats. (nih.gov)
Toxicity Evaluation of Aspartame1
- Genetic Toxicity Evaluation of Aspartame in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
Continued aspartame consumption1
- However, recent research has uncovered many harmful side effects of continued aspartame consumption. (earthclinic.com)
- In February 1984, the U.S. Food and Drug Administration (FDA) requested CDC's assistance in evaluating consumer complaints that FDA had received about consumption of aspartame-containing products. (cdc.gov)
- Criteria originally developed to assess potential adverse reactions to medications were adapted to evaluate the likelihood that symptoms reported by individuals through this passive surveillance system could be due to aspartame consumption (1,2). (cdc.gov)
- Moreover, details relating to the time between ingestion of aspartame and onset of symptoms often were incomplete because aspartame consumption was part of the daily routine. (cdc.gov)
- Evaluation of dose-response relationships might have been fruitful had individuals reported symptoms with increasingly high consumption of aspartame-containing products. (cdc.gov)
- Defendants in this lawsuit continue to maintain that aspartame is safe for consumption. (newswithviews.com)
- In fact, there are over 92 different health side effects associated with aspartame consumption . (naturalpedia.com)
- The defendants in those lawsuits number twelve and all produce or use the artificial sweetener aspartame as a sugar substitute in their products. (newswithviews.com)
- A huge study involving 340,045 men and 226,945 women, ages 50 to 69, found that the artificial sweetener aspartame doesn't raise the risk of cancer. (dvhardware.net)
- According to Dr. David Ludwig, an endocrinologist and professor of nutrition at Harvard Medical School, artificial flavor compounds like aspartame and MSG work in similar ways. (greenmatters.com)
- The Food and Drug Administration should immediately review the safety of the artificial sweetener aspartame, and possibly ban it, in light of a new study published in the European Journal of Oncology. (cspinet.org)
- CSPI has long urged that aspartame be better tested, but has not maintained that the artificial sweetener is harmful, except to some people in whom it causes headaches. (cspinet.org)
- PepsiCo said earlier this year that it would be replacing the aspartame used to sweeten Diet Pepsi with sucralose, another artificial sweetener more commonly known as Splenda. (medicaldaily.com)
- Scientifically speaking, aspartame is the name given to the artificial, non-saccharide sweetener, aspartyl phenylalanine-1-methyl ester. (earthclinic.com)
Approval of aspartame3
- This increase coincided with approval of aspartame for use in soft drinks in July 1983. (cdc.gov)
- From the clinical studies performed before FDA approval of aspartame, there was little to suggest that acute reactions would be likely to occur. (cdc.gov)
- According to the Affidavit, the doctor directing the studies has been missing since the approval of aspartame in 1984. (newswithviews.com)
- Plaintiffs maintain that this lawsuit will prove how deadly the chemical sweetener aspartame is when consumed by humans. (newswithviews.com)
- Assessments of the health impacts of the non-sugar sweetener aspartame are released today by the International Agency for Research on Cancer (IARC) and the World Health Organization (WHO) and the Food and Agriculture Organization (FAO) Joint Expert Committee on Food Additives (JECFA). (who.int)
- The aspartame industry consistently tries to rebut all findings with ridiculous reasons like in the Ramazzini Studies saying the rats had respiratory disease when respiratory disease is the dying process, and the rats were dying. (wnho.net)
- The study, conducted in Italy, found statistically significant increases in lymphomas and leukemias among female rats given aspartame. (cspinet.org)
- An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Aspartame (22839-47-0). (nih.gov)
- Thus, the aim of this study was to evaluate the effects of aspartame supplementation on dietary intake , physical, biochemical, and histopathological parameters in 18 male Wistar rats , at five weeks old (young mice ) treated for 21 days. (bvsalud.org)
- Throughout the experiment the rats treated with aspartame showed a significant increase in body weight and food intake compared to the control group . (bvsalud.org)
- Haemolymphoreticular neoplasias (HLRNs) from the Ramazzini Institute (RI) carcinogenicity studies on Aspartame (APM) in rats and mice were heterogeneously grouped over the years and different statistical methods were applied. (bvsalud.org)
- Citing "limited evidence" for carcinogenicity in humans, IARC classified aspartame as possibly carcinogenic to humans (IARC Group 2B) and JECFA reaffirmed the acceptable daily intake of 40 mg/kg body weight. (who.int)
- How many calories are there in Gelatin desserts, dry mix, reduced calorie, with aspartame, no added sodium ? (acaloriecounter.com)
- This option will ensure that the nutrition facts shown are 100% accurate for your specific amount of Gelatin desserts, dry mix, reduced calorie, with aspartame, no added sodium. (acaloriecounter.com)
- According to EcoWatch , aspartame mimics sugar in the mouth by stimulating the sweet taste buds on the tongue. (greenmatters.com)
- An extremely large intake of aspartame (equivalent to 17 cans of soda or 100 packets of Equal Sweetener) can slightly increase the amount of phenylalanine in breastmilk. (nih.gov)
- It was recognized from the outset that this investigation alone would be unlikely to establish any cause-and-effect relationship between the ingestion of aspartame and the occurrence of reported symptoms. (cdc.gov)
- Aspartame is not detectable in breastmilk after maternal ingestion because it is rapidly broken down in the mother's body. (nih.gov)
- Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults. (nih.gov)
- The methanol that results from the digestion of aspartame gets converted into formaldehyde, a toxic and carcinogenic chemical often used in embalming. (greenmatters.com)
- People who suffer from genetic disease phenylketonuria (PKU) and those who cannot metabolize phenylalanine normally need to avoid diet drinks and other products containing aspartame. (naturalpedia.com)
- Starting as soon as this summer, Diet Pepsi will be aspartame free - in stores, at least. (medicaldaily.com)
- John Sicher, the publisher of the industry tracker Beverage Digest, thought that making the aspartame version of Diet Pepsi available online would be a smart move for PepsiCo. (medicaldaily.com)
- In any case, avoiding aspartame-laden products and eating a clean diet is the best step toward healthy, toxin-free living. (earthclinic.com)
- Nos últimos anos, tem-se observado um aumento no consumo de alimentos diet e light por adolescentes ou por aqueles que estão à procura de uma alimentação com baixo teor calórico, surgindo, assim, diversos edulcorantes , como o aspartame . (bvsalud.org)
- The authors of the Italian study call for "urgent re-examination of permissible exposure levels of [aspartame] in both food and beverages, especially to protect children. (cspinet.org)
- Hemolymphoreticular Neoplasias from the Ramazzini Institute Long-term Mice and Rat Studies on Aspartame. (bvsalud.org)
- The request followed an increase in aspartame-related complaints in the latter half of 1983. (cdc.gov)
- These are researchers who have either researched aspartame for years like Monte and Bowen or even done one of the most damning studies in history on aspartame like Dr. Alemany showing how the formaldehyde embalms the body and damages DNA. (wnho.net)
- Zero calorie sweetener with aspartame by CHESTNUT HILL nutrition facts and analysis. (nutritionvalue.org)
- Only a very small amount of aspartame is needed to give food and beverages a sweet flavor because it is approximately 200 times sweeter than sugar, according to the American Cancer Society . (naturalpedia.com)
- Although it is prudent to avoid the use of aspartame in women who are nursing an infant with phenylketonuria, amounts that are typically ingested in aspartame-sweetened foods and beverages do not result in any additional risk to breastfed infants with phenylketonuria. (nih.gov)
- Plaintiffs maintain that Rumsfeld used his political muscle to get aspartame approved by the FDA despite objections of many FDA health researchers and negative studies. (newswithviews.com)
- According to the press release issued on this RICO lawsuit: "On or about September 8, 2004 an affidavit was signed describing the initial third world studies and the health hazards of aspartame. (newswithviews.com)
- The "double blind" studies showed conclusive evidence that aspartame caused severe health problems and even death to the exposed study group. (newswithviews.com)
- Yet, the false results were submitted to the FDA like the rest of the 150 G.D. Searle studies (on aspartame and other products), bearing a Searle Pathology-Toxicology project number. (newswithviews.com)
- Between the original studies showing everything from adenocarcinoma, brain tumors, testicular tumors, thyroid, pancreatic, uterine, ovarian and mammary tumors - at least for starters, the oncogene studies and Dr. Soffritti's studies anyone who says aspartame doesn't cause cancer is showing himself to be completely ignorant, unresearched or a downright fool. (wnho.net)
- However, new data has brought the results of those studies into question and there has been little consistency when it comes to linking cancer and aspartame. (greenmatters.com)
- The FDA immediately should ask the government's National Toxicology Program to conduct new animal studies to assess the cancer risk from aspartame. (cspinet.org)
- As a precautionary measure, in the several years it would take to design and conduct such studies, the FDA should consider ordering aspartame off the market," said CSPI executive director Michael F. Jacobson. (cspinet.org)
- The California Environmental Protection Agency has also called for further studies on aspartame. (cspinet.org)
- 3. Mutagenicity and genotoxicity studies of aspartame. (nih.gov)
- 4. In vivo cytogenetic studies on blends of aspartame and acesulfame-K. (nih.gov)
- Aspartame has side effects in the skin such as itching without a rash, lip and mouth reactions, hives, and aggravated respiratory allergies such as asthma. (naturalpedia.com)
- Then, there are those with aspartame allergies, who experience hives, rashes, or labored breathing when they accidentally ingest it. (greenmatters.com)
- These are independent researchers and Dr. Bowen who has been studying it for over 20 years has Lou Gehrigs from it because he used it before he researched it and accepted the lies of our FDA and the aspartame industry. (wnho.net)
- Aspartame is a man-made sweetener with almost no calories that is used in place of sugar. (naturalpedia.com)
- Aspartame is a man-made sweetener used to replace sugar. (naturalpedia.com)
- You've probably already heard one or more times that light products like Cola Light increase the risk of getting cancer, but according to the study this is false as aspartame, which replaces sugar, doesn't have nasty side-effects. (dvhardware.net)
- But is aspartame actually bad for you or is it just bad press concocted by Big Sugar? (greenmatters.com)
- You only need a small amount of aspartame to get the same sweetness you might be used to from sugar . (greenmatters.com)
- Created as a "safe" alternative to regular sugar, continued research has shown that aspartame is more harmful than helpful. (earthclinic.com)
- Being that aspartame is a sugar alternative designed to be safe and present in so many products, it may seem that little problem exists with the product. (earthclinic.com)
- Zero calorie sweetener with aspartame by CHESTNUT HILL belong to 'Granulated, Brown & Powdered Sugar' food category. (nutritionvalue.org)
- One of the most common sugar substitutes, aspartame is approved for use in more than 90 countries around the world and is used in 6,000 different products, including soft drinks, cereals, breath mints, chewing gum, hard candies. (businessinsider.com)
- A single gram of aspartame has the same amount of calories as a gram of sugar, but because it is 180 times sweeter than plain old sugar, you end up using a lot less to achieve the same sweetness. (businessinsider.com)
- Leatherhead reports that the global market for aspartame was worth 17,500 tonnes in 2010, equivalent to $320m in value terms. (bakeryandsnacks.com)
- As far as is known, complaints, such as those reported in this analysis as being related to aspartame use, have not been commonly reported in other countries in which aspartame is also in use. (cdc.gov)
- The quality and type of evidence that may be obtained by a passive surveillance system does not allow definitive determination of whether given symptoms are or are not caused by the agent under question--in this case, aspartame. (cdc.gov)
- An important criterion in assessing potential adverse reactions is the consistency of reported symptoms with rechallenge, i.e., the recurrence of symptoms after consuming aspartame-containing products a second time. (cdc.gov)
- If you still believe that aspartame is not dangerous you are in for a serious surprise. (mercola.com)
- Dr. Soffritti's research is just as damning proving once and for all that aspartame is a multipotential carcinogen which goes along with what FDA Toxicologist, Dr. Adrian Gross, told Congress, that it violated the Delaney Amendment because without a shadow of a doubt it caused tumors and cancer, and therefore no ADI should have been able to be set. (wnho.net)
- Dr. Soffritti's research is as damning as Dr. Alemany's because he not only proved aspartame causes cancer but that it can be passed on to a woman's offspring. (wnho.net)
- Aspartame: Diabetic Lifeline or Cancer-Causing Sweetener? (greenmatters.com)
- According to MedicineNet , aspartame has been linked to everything from pancreatic damage to cancer, heart disease , erectile dysfunction, and even Alzheimer's. (greenmatters.com)
- Does aspartame cause cancer? (greenmatters.com)
- The smallest amount of aspartame (20 milligrams per kilogram of body weight) that caused a significant increase in cancer incidence is in the ballpark of what many people consume. (cspinet.org)
- You have to understand aspartame is a chemical hypersensitization agent because of its poisonous nature as a deadly chemical poison. (wnho.net)
- This study will determine the effect of aspartame in the heterozygous p53 deficient (+/-) mouse, hemizygous Tg. (nih.gov)
- It goes a fair way toward allaying concerns about aspartame," said Michael Jacobson, head of the Center for Science in the Public Interest, which had urged the government to review the sweetener's safety after a troubling rat study last year. (dvhardware.net)
- As Dr. Ralph Walton who has also done a study on aspartame said, the correct ADI for aspartame is zero. (wnho.net)
- The change was influenced by customer feedback and, according to ABC News, executives' concerns that the public's fears about aspartame were causing sales to decline. (medicaldaily.com)
- The global aspartame market has been in a period of decline since the middle of the last decade, with global oversupply having eroded prices, it added. (bakeryandsnacks.com)
- At each of five concentrations plus a control group, fifteen animals per sex shall receive aspartame in the feed for 39-weeks. (nih.gov)
- The animals were randomly assigned into two groups control group (CG) - treated with distilled water by gavage and aspartame group (GA) - treated with 2ml/100g/day of aspartame . (bvsalud.org)
- The components of aspartame can harm a number of body organs and systems. (naturalpedia.com)
- Aspartame Boy hasn't written anything in a while, so his/her news feed is seriously out of date! (thespoof.com)
- The ACS also cites that while the FDA states the use of aspartame as a general purpose sweetener is safe, the European Food Safety Authority (EFSA) indicates a link in the risks associated with both leukemia, lymphatic, hematopoietic and brain cancers. (greenmatters.com)
- If Food Standards continues to put the aspartame industry's propaganda on their web site that has been proven to be absolutely absurd and non-scientific, its an abomination. (wnho.net)
- A new aspartame distribution deal will benefit the UK and Irish food and drink sector through security of supply, claims leading player Atlantic Chemicals Trading (ACT). (bakeryandsnacks.com)
- Although this claim remains unproven, there are still calls in some quarters for aspartame to be banned in food manufacture. (bakeryandsnacks.com)
- People who suffer from PKU and those who are taking medications for schizophrenia should avoid aspartame. (naturalpedia.com)
- So once you get back on it you're destined to react sometimes so severely it has caused victims to go into anaphylactic shock or like in the movie, Sweet Misery , a Code Blue who was revived, when she used some Crystal Lite Lemonade with aspartame, a very small glass. (wnho.net)
- These are not experts that are with the aspartame industry who defend aspartame and create the propaganda. (wnho.net)
- The aspartame industry has also been hit by falling demand in other parts of the world, such as Latin America and the Asia-Pacific region, continues the Leatherhead publication. (bakeryandsnacks.com)
- A review of the metabolism of the aspartyl moiety of aspartame in experimental animals and man. (nih.gov)
- Contained in the lawsuit is the key role played by current Secretary of Defense, Donald Rumsfeld ( search ) in helping to get aspartame pushed through the FDA. (newswithviews.com)
- Other side effects of aspartame include frequency of voiding and burning during urination, excessive thirst, fluid retention, leg swelling, bloating, and increased susceptibility to infection. (naturalpedia.com)