Flavoring agent sweeter than sugar, metabolized as PHENYLALANINE and ASPARTIC ACID.
Substances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed)
Peptides composed of two amino acid units.
An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.
A plant genus of the family ASTERACEAE. Members contain stevioside and other sweet diterpene glycosides. The leaf is used for sweetening (SWEETENING AGENTS).
One of the FLAVORING AGENTS used to impart a meat-like flavor.
The ability to detect chemicals through gustatory receptors in the mouth, including those on the TONGUE; the PALATE; the PHARYNX; and the EPIGLOTTIS.
Substances which are of little or no nutritive value, but are used in the processing or storage of foods or animal feed, especially in the developed countries; includes ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS (both plain and LOCAL); VEHICLES; EXCIPIENTS and other similarly used substances. Many of the same substances are PHARMACEUTIC AIDS when added to pharmaceuticals rather than to foods.
A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.
The minimum concentration at which taste sensitivity to a particular substance or food can be perceived.
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Salts and esters of cyclamic acid.
Flavoring agent and non-nutritive sweetener.
An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Drinkable liquids combined with or impregnated with carbon dioxide.
The process by which the nature and meaning of gustatory stimuli are recognized and interpreted by the brain. The four basic classes of taste perception are salty, sweet, bitter, and sour.
Laws concerned with manufacturing, dispensing, and marketing of drugs.
The collective designation of three organizations with common membership: the European Economic Community (Common Market), the European Coal and Steel Community, and the European Atomic Energy Community (Euratom). It was known as the European Community until 1994. It is primarily an economic union with the principal objectives of free movement of goods, capital, and labor. Professional services, social, medical and paramedical, are subsumed under labor. The constituent countries are Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden, and the United Kingdom. (The World Almanac and Book of Facts 1997, p842)
An iterative questionnaire designed to measure consensus among individual responses. In the classic Delphi approach, there is no interaction between responder and interviewer.
A course of food intake that is high in FATS and low in CARBOHYDRATES. This diet provides sufficient PROTEINS for growth but insufficient amount of carbohydrates for the energy needs of the body. A ketogenic diet generates 80-90% of caloric requirements from fats and the remainder from proteins.
A condition characterized by an abnormally elevated concentration of KETONE BODIES in the blood (acetonemia) or urine (acetonuria). It is a sign of DIABETES COMPLICATION, starvation, alcoholism or a mitochondrial metabolic disturbance (e.g., MAPLE SYRUP URINE DISEASE).
A diet that contains limited amounts of CARBOHYDRATES. This is in distinction to a regular DIET.
Decrease in existing BODY WEIGHT.
A two-person sport in which the fists are skillfully used to attack and defend.
A sport consisting of hand-to-hand combat between two unarmed contestants seeking to pin or press each other's shoulders to the ground.

Interaction of nucleotides with Asp(351) and the conserved phosphorylation loop of sarcoplasmic reticulum Ca(2+)-ATPase. (1/86)

The nucleotide binding properties of mutants with alterations to Asp(351) and four of the other residues in the conserved phosphorylation loop, (351)DKTGTLT(357), of sarcoplasmic reticulum Ca(2+)-ATPase were investigated using an assay based on the 2', 3'-O-(2,4,6-trinitrophenyl)-8-azidoadenosine triphosphate (TNP-8N(3)-ATP) photolabeling of Lys(492) and competition with ATP. In selected cases where the competition assay showed extremely high affinity, ATP binding was also measured by a direct filtration assay. At pH 8.5 in the absence of Ca(2+), mutations removing the negative charge of Asp(351) (D351N, D351A, and D351T) produced pumps that bound MgTNP-8N(3)-ATP and MgATP with affinities 20-156-fold higher than wild type (K(D) as low as 0.006 microM), whereas the affinity of mutant D351E was comparable with wild type. Mutations K352R, K352Q, T355A, and T357A lowered the affinity for MgATP and MgTNP-8N(3)-ATP 2-1000- and 1-6-fold, respectively, and mutation L356T completely prevented photolabeling of Lys(492). In the absence of Ca(2+), mutants D351N and D351A exhibited the highest nucleotide affinities in the presence of Mg(2+) and at alkaline pH (E1 state). The affinity of mutant D351A for MgATP was extraordinarily high in the presence of Ca(2+) (K(D) = 0.001 microM), suggesting a transition state like configuration at the active site under these conditions. The mutants with reduced ATP affinity, as well as mutants D351N and D351A, exhibited reduced or zero CrATP-induced Ca(2+) occlusion due to defective CrATP binding.  (+info)

On the sweetness of N-(trifluoroacetyl)aspartame. (2/86)

A panel of tasters has found that the N-trifluoroacetyl derivative of aspartame is five times less sweet than the parent compound, contrary to the tenet in the literature, but consistent with sweet receptor models which require this nitrogen to exist in protonated form.  (+info)

Genetic taste responses to 6-n-propylthiouracil among adults: a screening tool for epidemiological studies. (3/86)

Genetically mediated taste responsiveness to 6-n-propylthiouracil (PROP) has been linked to reduced acceptance of some bitter foods. In this community-based study male (n = 364) and female (n = 378) adults enrolled in a self-help dietary intervention trial were screened for PROP taster status. Respondents, aged 18--70 years, were mailed filter papers impregnated with PROP or with aspartame solutions. They received instructions to rate taste intensity and hedonic preference using nine point category scales. Women rated PROP as more bitter than did men. Both sweetness and bitterness ratings were lower for older adults. Taste responsiveness to PROP was unrelated to body mass index in women or men. Higher bitterness ratings for PROP were weakly associated with higher sweetness ratings for aspartame, but were unrelated to sweet taste preferences. Successful administration of PROP filter papers by mail suggests new avenues for the screening of taste phenotypes in epidemiological studies.  (+info)

Whole nerve chorda tympani responses to sweeteners in C57BL/6ByJ and 129P3/J mice. (4/86)

The C57BL/6ByJ (B6) strain of mice exhibits higher preferences than does the 129P3/J (129) strain for a variety of sweet tasting compounds. We measured gustatory afferent responses of the whole chorda tympani nerve in these two strains using a broad array of sweeteners and other taste stimuli. Neural responses were greater in B6 than in 129 mice to the sugars sucrose and maltose, the polyol D-sorbitol and the non-caloric sweeteners Na saccharin, acesulfame-K, SC-45647 and sucralose. Lower neural response thresholds were also observed in the B6 strain for most of these stimuli. The strains did not differ in their neural responses to amino acids that are thought to taste sweet to mice, with the exception of L-proline, which evoked larger responses in the B6 strain. Aspartame and thaumatin, which taste sweet to humans but are not strongly preferred by B6 or 129 mice, did not evoke neural responses that exceeded threshold in either strain. The strains generally did not differ in their neural responses to NaCl, quinine and HCl. Thus, variation between the B6 and 129 strains in the peripheral gustatory system may contribute to differences in their consumption of many sweeteners.  (+info)

Application of the U and gamma' models in binary sweet taste mixtures. (5/86)

The U and Gamma' models of sensory interactions, successfully applied in olfaction for several years, are tested here using data from published studies on sweetness. The models are subsequently tested on new data obtained in studies of binary mixtures of four sodium sulfamates. The U model allows for the estimation of a global interaction, whereas the Gamma' model allows for the distinction between that which is due to an intrinsic interaction in the mixture itself and that which may be due to the power function exponents in the mixture. The models give satisfactory predictions for observed phenomena of sweet taste suppression, synergism or pure additivity. Additionally, they appear to be more suitable than other models recently applied in taste, particularly the equiratio model. Application of the models to the sulfamate mixtures, reveals additivity for sodium cyclohexylsulfamate (cyclamate)/potassium cyclohexylsulfamate and sodium cyclohexylsulfamate/sodium exo-2-norbornylsulfamate, respectively; whereas for sodium cyclohexylsulfamate/sodium 3-bromophenylsulfamate, the models revealed a slight hypo addition which is simply due to the dissimilarity values of the power function exponents of the components.  (+info)

The effect of various substances on the suppression of the bitterness of quinine-human gustatory sensation, binding, and taste sensor studies. (6/86)

The purpose of this study was to quantify the degree of suppression of the perceived bitterness of quinine by various substances and to examine the mechanism of bitterness suppression. The following compounds were tested for their ability to suppress bitterness: sucrose, a natural sweetener; aspartame, a noncaloric sweetener; sodium chloride (NaCl) as the electrolyte; phosphatidic acid, a commercial bitterness suppression agent; and tannic acid, a component of green tea. These substances were examined in a gustatory sensation test in human volunteers, a binding study, and using an artificial taste sensor. Sucrose, aspartame, and NaCl were effective in suppressing bitterness, although at comparatively high concentrations. An almost 80% inhibition of bitterness (calculated as concentration %) of a 0.1 mM quinine hydrochloride solution required 800 mM of sucrose, 8 mM of aspartame, and 300 mM NaCl. Similar levels of bitterness inhibition by phosphatidic acid and tannic acid (81.7, 61.0%, respectively) were obtained at much lower concentrations (1.0 (w/v)% for phosphatidic acid and 0.05 (w/v)% for tannic acid). The mechanism of the bitterness-depressing effect of phosphatidic acid and tannic acid was investigated in terms of adsorption and masking at the receptor site. With phosphatidic acid, 36.1% of the bitterness-depressing effect was found to be due to adsorption, while 45.6% was due to suppression at the receptor site. In the case of 0.05 (w/v)% tannic acid, the total bitterness-masking effect was 61.0%. The contribution of the adsorption effect was about 27.5% while the residual masking effect at the receptor site was almost 33%. Further addition of tannic acid (0.15 (w/v)%), however, increased the bitterness score of quinine, which probably represents an effect of the astringency of tannic acid itself. Finally, an artificial taste sensor was used to evaluate or predict the bitterness-depressing effect. The sensor output profile was shown to reflect the depressant effect at the receptor site rather well. Therefore, the taste sensor is potentially useful for predicting the effectiveness of bitterness-depressant substances.  (+info)

Formaldehyde-induced shrinkage of rat thymocytes. (7/86)

To test the possibility that micromolar formaldehyde, a metabolite of methanol derived from aspartame, exerts cytotoxicity, its effect on rat thymocytes was examined under the in vitro condition using a flow cytometer. Incubation of thymocytes with formaldehyde at 100 micro M or more for 24 h significantly increased the populations of shrunken cells and cells with hypodiploid DNA. The peak blood concentration of methanol in human subjects administered abuse doses of aspartame has been reported to exceed 2 mg/dL (625 micro M). It would increase the population of thymocytes undergoing apoptosis if formaldehyde at 100 micro M or more appears in the blood after administration of aspartame.  (+info)

Modified DNA aptamers against sweet agent aspartame. (8/86)

We obtained a modified DNA aptamer against sweetener, aspartame, by in vitro selection method. The modified DNA was prepared from dATP, dGTP, dCTP and a modified dTTP bearing a terminal amino group at C-5 position in place of thymidine by PCR using a hyper thermophilic DNA polymerase, KOD Dash DNA polymerase. The synthetic 102-mer DNA with a 60-mer random region was used as an initial template for the PCR. The PCR-amplified modified DNA library was applied to an aspartame-agarose column, and then the bound modified DNA was eluted from the column for the affinity chromatography selection. Repeating the procedure, we selected the modified DNA aptamer against aspartame.  (+info)

A List of Foods Containing Aspartame. Health concerns raised about the safety of aspartame, including increased cancer risk, have not been validated through research. The Academy of Nutrition and Dietetics, Food and Drug Administration (FDA) and American Cancer Society acknowledge that aspartame is safe for general use within a recommended intake. The FDA sets an Acceptable Daily Intake (ADI) for aspartame at 50 milligrams per kilogram, equivalent to 21 aspartame sweetened beverages for a 165 pound person.. Aspartame is safe for use by nearly all healthy individuals, including those with diabetes. The one exception is people who have phenylketonuria (PKU). People with PKU are unable to metabolize phenylalanine, a component of aspartame. A warning statement on all products containing aspartame advises against consuming it, if you have PKU.. Some not so obvious foods and products contain aspartame. For example, condiments that typically contain sugar, such as ketchup, dressings, sauces and ...
Dr. Janet Hull who just wrote a book called Sweet Poison talks about the dangers of Aspartame poisoning. She almost died from aspartame poisoning in 1991 and has been on a mission to spread the word to the government and anyone who will listen to tell them about her story. Dr. Janet Hull has been documenting the history of aspartame, government reports, senate hearings on aspartame safety and case history, including death. Through her research she has found that there are 92 disease symptoms that aspartame creates.. Dr. Hull notes that a lot of the symptoms suffered by those with Fibromyalgia and CFIDS are the same as some of the symptoms of aspartame poisoning. The components that make up aspartame can lead to a number of health problems. Side effects can occur gradually, immediately, or can be acute reactions. There is an enormous amount of the population that is suffering from the side effects of aspartame. For these people, they cant understand why drugs, supplements, and herbs dont ...
Aspartame is safe for both children and adults. According to extensive studies, there has been no evidence to suggest that aspartame use is risky for expecting mothers and their unborn children. Still, we advise you to always check with your doctor before switching to aspartame, to make sure that its the right choice for you.. So why is aspartame safe, exactly? Simply because its components are naturally occurring substances, that are swiftly broken down by your body. There is no build-up in your organs or blood. Aspartame also contains a very small amount of calories, that doesnt add anything to your diet. It has no nutritional value and does not spike your blood sugar levels. This makes it easier for you to take control of your body and become healthy. Lastly, it does not cause any diseases or impairments. Is aspartame safe for diabetics and obese people? According to the American Diabetes Association (ADA), it most certainly is! In fact, aspartame is mostly beneficial to people who want to ...
Not only has my life been changed by aspartame in ways that are apparently never going to be reversed (my eyesight and my memory) but recently I had a very hard time acquiring health insurance. The insurance underwriter actually told my insurance agent that he ran across 6,000 cases like mine (people claiming aspartame made them sick) a month. Now I do not know how many people his location underwrites in a month, whether he meant 6,000 people a year, whether he was exaggerating or even whether my agent was being honest with me. It is just one more piece of my aspartame story and one more way it has left its ugly mark on my life. Now I know this is America and I am ultimately in charge of where I end up in life, but why, when we have a system in place to protect people, does that very system seem so hell bent on writing off aspartame victims as unreliable at the possible cost of more injuries ...
While there are a lot of products that contain aspartame, it is highly unlikely that one would consume enough aspartame to exceed the ADI in a 24 hour period. Additionally, it is important that the ADI has a built in safety factor of 100 fold, so even if the ADI were exceeded, the amount of aspartame consumed would not reach dangerous levels. Further, the amount of aspartame used is miniscule and used to sweeten foods and beverages to remove calories and provide a low-calorie product. In recent research there have been no links to aspartame causing neurological problems, worsening disease states, or causing increased craving for sweet food/beverages. Humans innately crave sweet tasting foods and beverages. There have also been no scientific studies that can prove any adverse side effects. It is important to keep in mind that while these studies may have shown associations between aspartame and these side effects, it is not a cause and effect model and is untrue to say that aspartame is the cause ...
People try the sweetener aspartame when they are trying to lose weight. The reasoning is that it has no calories and can be substituted for sugar which is high calorie. Dieters would be surprised to know that research has shown that Aspartame actually increases the weight and waistlines of its users [1].. Along with weight gain there are other serious health considerations involved with Aspartame. Aspartame has been associated with cardiovascular incidents. In fact, a decade-long study of 60,000 women has confirmed that drinking diet soda sweetened with aspartame is linked with a 30 percent increase in heart attack risk and a 50 percent increase in death risk. These findings were presented at American College of Cardiology [2] Italian studies by Dr. Morand Soffriti concluded that aspartame is a multi-carcinogenic agent in rats. Further its multi-carcinogenic effects were evident even at daily dose 20mg/kg b.w. much less than the current ADI of 50mg/kg b.w. (22, Sofritti et al)[3]. The daily ...
There are 92 documented symptoms of ASPARTAME, from coma to death. The majority of them are all neurological, because the ASPARTAME destroys the nervous system. ASPARTAME Disease is partially the cause to what is behind some of the mystery of the Dessert Storm health problems some of the soldiers are experiencing. The burning tongue and other problems discussed in over 60 cases can be directly related to the consumption of an ASPARTAME product. Several thousand pallets of diet pop were shipped to the Dessert Storm troops. (Heat can liberate the methanol from the ASPARTAME at 86 degrees F). Diet pop sat in the 120 degree F Arabian sun for weeks at a time on pallets. The service men and women drank this diet pop all day long. All of their symptoms are identical to ASPARTAME poisoning ...
concept ,wikipedia=https://en.wikipedia.org/wiki/Aspartame ,image=Aspartame.svg ,constitutes=drug ,start=1965 ,sourcewatch=http://www.sourcewatch.org/index.php/Aspartame ,description=Widely used artificial sweetener with increasingly suspect looking health effects. }} Aspartame is a [[drug]] that was first made in 1965. It is widely used as a [[sugar]]-free sweetener worldwide. It has been banned twice by the , but re-legalised. Its safety is a continued subject of debate. ==Official narrative== A panel of experts set up by the [[European Food Safety Authority]] concluded in 2013 that aspartame is safe for human consumption at current levels of exposure.,ref>{{cite journal,title=Scientific Opinion on the re-evaluation of aspartame (E 951) as a food additive,journal=EFSA Journal,date=10 December 2013,volume=11,issue=12,page=263,doi=10.2903/j.efsa.2013.3496,url=http://www.efsa.europa.eu/en/efsajournal/pub/3496.htm,doi-broken-date=2017-01-28}},/ref> Evidence does not suggest that aspartame ...
US Food and Drug Administration Statement on European Aspartame Study. CFSAN/Office of Food Additive Safety. April 20, 2007. The FDA has completed its review concerning the long-term carcinogenicity study of aspartame, conducted by the European Ramazzini Foundation (ERF), located in Bologna, Italy. FDA reviewed the study data made available to them by ERF and finds that it does not support ERFs conclusion that aspartame is a carcinogen. Additionally, these data do not provide evidence to alter FDAs conclusion that the use of aspartame is safe.. Aspartame was first approved in the United States in 1981 and is one of the most widely used artificial sweeteners. When metabolised by the body, aspartame is broken down into two common amino acids, aspartic acid and phenylalanine, and a third substance, methanol. These three substances are available in similar or greater amounts from eating common foods.. Considering results from the large number of studies on aspartames safety, including five ...
China White Powder Nutrition Enhancers Aspartame 99%, Find details about China Aspartame, Aspartame 99% from White Powder Nutrition Enhancers Aspartame 99% - Zibo Qingxin Chemicals Co., Ltd.
Birth defects and subsequent generational stigmas. The finding of aspartame metabolites in DNA clearly has profound implications. I have described severe problems in the fetus or the infants of parents-including fathers-who consumed aspartame at the time of conception and/or during pregnancy.. Epidemiological studies will be necessary to corroborate the role of aspartame consumption in medical, neurological, metabolic, immune and neoplastic disorders involving subsequent generations.. The urgent need for action. It is clear to all who have studied the matter that the initial approval of aspartame by the FDA in l981-in the face of severe objections from its in-house scientists, consultants for the General Accounting Office, and even a Public Board of Inquiry-was an erroneous political decision. This opinion is supported by considerable clinical experience, an increasing number of credible scientific studies, and demographic evidence relating to the contributory role of aspartame sodas and other ...
One would think that with the extreme and almost omnipresent dangers of aspartame that there would be far less of the substance on the market compared to a decade or two ago. But, with fully sanctioned advertisements telling you just how great products are which contain aspartame, there seems to be no end in sight for this dangerous edible chemistry experiment. There have been, however, several dozen studies on just how viable the purely artificial sweetener actually is for the human body, mostly ignored by the general populace and still consumed just as much of the sweetener as before.. Methanol, Biproduct of Aspartame Linked to Autism, Preterm Delivery. Among these studies is a comprehensive one on Methanol, the primary alcoholic component used in the production of aspartame. A retired food scientist and Professor Emeritus of Food Science and Nutrition at the Arizona State University Dr. Woodrow Monte describes how the toxic chemical methanol and its use in the production of aspartame and ...
Have you ever heard the term aspartame? It sounds weird and it is definitely a chemical compound. But did you know that this substance is included in your favorite soft drinks and beverages? Aspartame, no matter how ridiculous it sounds, is an artificial sweetener that is added to foods and drinks to acquire distinct level of sweetness. While it is definitely one of the reasons that youve kept coming back for more of your favorite soda, your body may not like it at all because of the health woes that it may cause in the long run. Lets get to know more about Aspartame and its effects to our health.. History. Aspartame was first discovered in 1965, but it was several years later when FDA finally provided an approval of its use in carbonated drinks, beverages, and foods. NutraSweet, which was manufactured in 1965, was the very first brand of aspartame sold to the market. Today, it comes with other brand names such as Equal and Spoonful. Since then, it became the core of hot topics about its ...
This new study shows the importance of the quality of research. Most of the past studies showing no link between aspartame and cancer have been criticized for being too short in duration and too inaccurate in assessing long-term aspartame intake. This new study solves both of those issues. The fact that it also shows a positive link to cancer should come as no surprise, because a previous best-in-class research study done on animals (900 rats over their entire natural lifetimes) showed strikingly similar results back in 2006: aspartame significantly increased the risk for lymphomas and leukemia in both males and females. More worrying is the follow on mega-study, which started aspartame exposure of the rats at the fetal stage. Increased lymphoma and leukemia risks were confirmed, and this time the female rats also showed significantly increased breast (mammary) cancer rates. This raises a critical question: will future, high-quality studies uncover links to the other cancers in which aspartame ...
Aspartame Sugar manufacturers directory - trade platform for China Aspartame Sugar manufacturers and global Aspartame Sugar buyers provided by Bossgoo.com
This new study shows the importance of the quality of research. Most of the past studies showing no link between aspartame and cancer have been criticized for being too short in duration and too inaccurate in assessing long-term aspartame intake. This new study solves both of those issues. The fact that it also shows a positive link to cancer should come as no surprise, because a previous best-in-class research study done on animals (900 rats over their entire natural lifetimes) showed strikingly similar results back in 2006: aspartame significantly increased the risk for lymphomas and leukemia in both males and females. More worrying is the follow on mega-study, which started aspartame exposure of the rats at the fetal stage. Increased lymphoma and leukemia risks were confirmed, and this time the female rats also showed significantly increased breast (mammary) cancer rates. This raises a critical question: will future, high-quality studies uncover links to the other cancers in which aspartame ...
You say you were advised, but as Public Health Minister with the health interests of the UK at stake, dont you think you should have researched the issue? There are front groups for the aspartame industry like the Calorie Control Council who will advise all day long that aspartame is safe with full knowledge its not.. I believe I have more concern for the health of the people of Europe than you do because I came to England not to advise but to document the facts on aspartame beyond any shadow of a doubt. The lives of the people are at stake. It was obvious the aspartame industry knew I was coming. I was met with follow me by immigration. They didnt even ask my name. Immediately one of their people went through my suitcases and confiscated every record on aspartame including books by the experts. They knew exactly what they were looking for. I was detained three and a half hours. Immigration even wanted to know how many people would be at each of my lectures.. Finally I was taken to a ...
Contains an extensive index to facilitate quick access to specific information. Contents. Introduction: Regulatory Requirements for Human Studies. Clinical Studies with Food Additives. The Safety Assessment of Aspartame: Scientific and Regulatory Considerations. Acceptable Daily Intake and Estimation of Consumption.. Metabolism and Pharmacokinetic Studies in Humans: Metabolism and Pharmacokinetics of Radiolabeled Aspartame in Normal Subjects. Effects of Aspartame Ingestion on Plasma Aspartate, Phenylalanine, and Methanol Concentrations in Normal Adults. Effects of Aspartame Ingestion on Plasma Aspartate, Phenylalanine, and Methanol Concentrations in Potentially Sensitive Populations. Safety Evaluation in Pregnancy.. Tolerance in Various Populations: Tolerance in Healthy Adults and Children. Tolerance in Individuals with Diabetes. Tolerance in PKU Heterozygotes.Tolerance in Individuals with Renal Disease. Tolerance in Individuals with Liver Disease.. Evaluation of Anecdotal Medical Complaints: ...
Aspartame has never been tested on humans for safety.. Over a billion people consume aspartame in their foods and beverages across the world daily, believing it to be a safe ingredient.. Aspartame is the number one sweetener used in U.S. hospitals by doctors, nurses, visitors and patients.. Each of the three ingredients in the synthetic, chemical combination Aspartame - which is comprised of 50 percent phenylalanine, 40 percent aspartic acid, and 10 percent methanol - pose their own dangers.. The EPAs recommended limit for consumption of methanol is 7.8 milligrams per day, but a one liter bottle of an Aspartame-sweetened beverage contains over 50 mg of methanol! Heavy users of Aspartame-containing products consume over 250 mg daily of methanol - thats 30 times the EPA limit!. In 2013, The IDFA (International Dairy Foods Association) and the NMPF (National Milk Producers Federation) filed a petition with the FDA to change the standard entity of milk plus 17 other dairy products so that they can ...
After years of experience as a mother and a teacher, I truly believe that all schools should be deeply concerned about their students consumption of aspartame, an artificial sweetener unfortunately found in a multitude of products.. Aspartame is found in many brands of diet soda and other diet drinks, gum, candy, flavored fizzy water and many diabetic foods. It is even in health drinks, yogurt, gelatins, puddings, wine coolers, cereals, breath strips and mints; some medicines and chewable childrens vitamins also contain aspartame.. Most students realize that illegal drugs and smoking are bad for them, but many dont know anything about the hazards of aspartame. With all the media attention on obesity these days, students will start using even more diet products.. Obviously, obesity is a serious problem! However, turning to artificial sweeteners in an attempt to lose weight or prevent weight gain is not the answer. In fact, artificial sweeteners have been proven to contribute to weight gain. ...
Only after longer aspartame usage does liver damage cause blood methanol levels to measurably rise because the liver mitochondria are so damaged that the liver no longer quickly processes either methyl or ethyl (drink) alcohol. Then the acute methanol poisoning is directly measurable from lab results, as the blood methanol level elevates. This entire sequence or toxic axis begins with your very first dose of aspartame. Both acute and chronic poisonings from this methanol toxic axis, and other additive and synergistic aspartame poisonings, steadily accumulate in the aspartame consumer. We continue to get reports of people dying of methanol poisoning. Charles Fleming died and his wife, a Sunday School teacher, remains in a prison in Virginia. The detective on the case said, Diane is innocent but because I was promoted I could not stop the indictment. Be warned no diabetic should ever consume wood alcohol. The FDA did no NOAEL on methanol. Without it you cannot set an ADI, allowable daily ...
Aspartame is also the number one source of side effect complaints to the US Food and Drug Administration (FDA), with over 10,000 complaints filed and over 91 documented symptoms related to its consumption.. Most recently, studies are also starting to confirm lingering suspicions that artificial sweeteners like aspartame may play a role in the development of Alzheimers disease, a serious form of dementia that is now thought to kill over half a million Americans each year.. The key mechanism of harm appears to be methanol toxicity-a much-ignored problem associated with aspartame in particular.. In a previous interview, toxicology expert Dr. Woodrow Monte (author of the book While Science Sleeps: A Sweetener Kills), explained the links between aspartame and methanol toxicity and the formation of formaldehyde. In light of the latest research, this interview is more relevant than ever, which is why I included in the video above.. Studies using Mice have shown that Methanol Toxicity Leads to ...
http://groups.yahoo.com/group/aspartameNM/message/1126 same amount of methanol (source of formaldehyde, formic acid) from aspartame as from dark wines and liquors: Utz: Murray 2004.10.19 rmforall From: Jeffrey P Utz ,jeffutz at juno.com, To: ,Quackbusters at yahoogroups.com, Subject: Re: [Quackbusters] Aspartame -- Sweet Or Sour? Thea Jourdan, The London Daily Mail 2004.10.04: Murray 2004.10.18 rmforall Date: Tuesday, October 19, 2004 6:21 AM Funny, you anti aspartame folks claim the ethanol in fruit is an antidote for the methanol in fruit. Funny, how in liquor, it doesnt do this. Could you please provide references for the 11% methanol in dark wines and liquors, as well as how these cause headaches? Jeff On Mon, 18 Oct 2004 21:30:00 -0600 Rich Murray ,rmforall at comcast.net, writes: http://groups.yahoo.com/group/aspartameNM/message/1125 Aspartame -- Sweet Or Sour? Thea Jourdan, The London Daily Mail 2004.10.04: Murray 2004.10.18 rmforall [ Comments by Rich Murray are in square brackets. ...
Each year, Americans consume about 5,250 tons of aspartame in total. 86 percent of this aspartame (4,500 tons) is from the consumption of diet sodas. Diet soda is the largest dietary source of aspartame in the U.S. A study recently published at the beginning of December 2012 links the consumption of Aspartame to increased risk of Lymphoma and Leukemia. The […]
http://groups.yahoo.com/group/aspartameNM/message/1165 short review: research on aspartame (methanol, formaldehyde, formic acid): Murray 2005.04.09 Rich Murray, MA Room For All rmforall at comcast.net 505-501-2298 1943 Otowi Road Santa Fe, New Mexico 87505 USA http://groups.yahoo.com/group/aspartameNM/messages group with 180 members, 1,165 posts in a public, searchable archive http://groups.yahoo.com/group/aspartameNM/message/1071 research on aspartame (methanol, formaldehyde, formic acid) toxicity: Murray 2004.04.29 rmforall http://groups.yahoo.com/group/aspartameNM/message/1143 methanol (formaldehyde, formic acid) disposition: Bouchard M et al, full plain text, 2001: substantial sources are degradation of fruit pectins, liquors, aspartame, smoke: Murray 2005.04.02 rmforall Aspartame (NutraSweet, Equal, Canderel, E951), after eight years of controversy, was suddenly and capriciously approved by a new FDA commissioner, Arthur Hull Hayes, Jr, just appointed by President Reagan, a pharmacologist ...
How much aspartame do you consume? How often do you drink a diet coke or other diet sodas? How many times a week do you eat a sugar free yoghurt? How about aspartame flavoured cereal, chewing gum, puddings, cakes, juices or one of the other 6,000 products that contain aspartame? Aspartame dangers will go into how this
From Dr. Betty Martini, D.Hum. 6-15-7. Statement from Dr. Russell Blaylock, MD. Dear Betty,. My review of the first Ramazzini Study concluded that the study was one of the best designed, comprehensive and conclusive studies done to date on the multipotent carcinogenic potential of aspartame.. This second study is even more conclusive, in that it shows a dose-dependent statistically significant increase in lymphomas/ leukemia in both male and female rats exposed to aspartame. These two cancers are the fastest growing cancers in people under age 30.. Also, of major concern is their finding of statistically significant increases in breast cancer in animals exposed to aspartame. With newer studies clearly indicating that toxic exposures during fetal development can dramatically increase the cancer risk of the offspring, this study takes on a very important meaning to all pregnant women consuming aspartame products. Likewise, small children are at considerable risk of the later development of these ...
Why havent you heard about aspartame poisoning before? Partly because the diet industry is worth trillions of American dollars to corporations, and they want to protect their profits by keeping the truth behind aspartames dangers hidden from the public. When NutraSweet was introduced for the second time in 1981, a diet craze revolutionized Americas eating protocols and a well-oiled money machine was set into motion changing modern lifestyles.. After more than twenty years of aspartame use, the number of its victims is rapidly piling up, and people are figuring out for themselves that aspartame is at the root of their health problems. Patients are teaching their doctors about this nutritional peril, and they are healing themselves with little to no support from traditional medicine.. What can you do about aspartame poisoning?. Set an example by changing your diet.. - Tell everyone you know.. - Talk to the schools and day care centers. Offer to speak at parent-teachers meetings.. - Contact ...
We encourage considerate reader contributions on any attention-grabbing topic in the information. On the 18th, he did not use a condom. BJOG: a muslim women and pregnancy journal of obstetrics and gynaecology aspartame and pregnancy risks, 1315-1324, doi:10. Some women notice that the areola has a darker color and it might also aspartame and pregnancy risks into bigger. You may also lie dealing with the inner curve aspartame and pregnancy risks relaxation your belly on the middle, with your head and neck on the upper finish. The level of aspartame and pregnancy risks hormone in blood or urine depends upon the particular day, following fertilization. Its possible youll feel that you could not wait to fulfill your first born daughter. It tends to weigh down the again causing ache. Statistical data of adolescent moms who had a baby whose weight is decrease than the ideal have been reported in the year 2002. Sejal Shah, one of the researchers who conducted the study. The word just means that your ...
The artificial sweetener aspartame, a dipeptide with the formula Asp-Phe-me, is produced using a cloned micrcorganism [sic]. A DNA which codes for a large stable peptide comprised of the repeating amino acid sequence (Asp-Phe)n is inserted into a cloning vehicle which in turn is introduced into a suitable host microorganism. The host microorganism is cultured and the large peptide containing the repeating Asp-Phe sequence is harvested therefrom. The free carboxyl group of the large peptide is benzylated and then hydrolysed to benzyl Asp-Phe dipeptides. This dipeptide is methylated and then debenzylated to form aspartame ...
During observations of thousands of children diagnosed with ADD and ADHD, it was documented that they had a complete change in their behaviors after the aspartame had been removed from their diets. Ritalin and other behavior modification prescription drugs were no longer needed. The foods that the children were being fed that were supposed to have been better for them than sugar, were in fact slowly poisoning them on a daily basis.. It has been said aspartame can cause birth defects such as mental retardation if taken at the time of conception and during the early stage of pregnancy. There have been numerous cases relating to children who have suffered grand mal seizures amongst other neurological disturbances due to the use of Nutra Sweet. Artificial sweeteners should never be given to children!. It is not easy to convince parents that aspartame is bad for their child and may be the reason for the childs illness. Stevia is a sweet herb that helps in the metabolism of sugar and would be ideal ...
Aspartame. Aspartame is an artificial non-saccharide sweetener invented in the 1980s. It was commonly known through its popular brand names such as Spoonfuls, Sweetmate, and Equal. Aspartame is derived from amino-acids and it is metabolized and digested by the body just like food containing protein. Aspartame is about 200 times sweeter than sugar so only a tiny amount of this sweetener can satisfy your sweet cravings. Although aspartame comes very close to sugar in its taste profile, the taste still differs significantly in how it affects your receptors and how long it lasts.. Aspartame can be found in various types of products such as desserts, different kinds of snack foods, gums and candies, salad dressings, beverages, and breakfast cereals. Because of the way it breaks down, aspartame is not a good sweetener for baking and does not support a long shelf life of a product.. Aspartame is one of the most thoroughly tested food additives on the market. It is currently considered safe, although ...
An independent study done by European Ramazzini Foundation of Oncology and Environmental Sciences in Italy shows the intake of aspartame at far less than daily allowable levels is multi-carcinogenic (lymphomas and leukemias) in laboratory rats. Aspartame is marketed as Nutrasweet, Equal, and Aminosweet and commonly found in diet products such as diet sodas.. First Experimental Demonstration of the Multipotential Carcinogenic Effects of Aspartame Administered in the Feed to Sprague-Dawley Rats. Our study shows that APM is a multipotential carcinogenic compound whose carcinogenic effects are evident even at a daily dose of 20 mg/kg bw, much less than the current ADI for humans in Europe (40 mg/kg bw) and in the United States (50 mg/kg bw).. The results of carcinogenicity bioassays in rodents are consistent predictors of human cancer risks (Huff 1999; Rall 1995; Tomatis et al. 1989). The results of our study therefore call for an urgent reexamination of the present guidelines on the use and ...
New Aspartame Replacement - Cuddly Name, Harmful to Your Health. What if aspartame had a less ominous-sounding name, something dreamed up by marketing wizards that was designed to sound safe and harmless?. Thats exactly what the popular artificial sweetener Splenda has going for it, but many people still dont know the harmful side effects its been linked to. Splenda is now being added to Diet Pepsi (along with a second harmful chemical well get to later), but it may not be much better for your health than aspartame after all.. While it was once marketed as a natural form of sugar with no calories, Splenda is actually the result of a five-part laboratory process that takes an original sugar molecule and adds three molecules of chlorine to the mix, turning it into something unnatural and foreign to the body, meaning your body has no way of properly metabolizing it.. Splenda also has a habit of staying inside your body, as at least 15% of it is not excreted in a timely manner according to this ...
About a year ago, I covered aspartame, the sometimes-maligned intense artificial sweetener. There is still a camp of substantial size insisting aspartame is deadly. Of course, its widely sold, and still FDA-approved, etc. There is one group of people for whom aspartame is undisputedly dangerous, however: phenylketonurics.
Aspartame consumption is implicated in the development of obesity and metabolic disease despite the intention of limiting caloric intake. The mechanisms responsible for this association remain unclear, but may involve circulating metabolites and the gut microbiota. Aims were to examine the impact of …
IFIC Statement. Todays opinion by the European Food Safety Authority (EFSA) has once again shown the strong evidence available to support aspartames safe use in foods and beverages. In addition to being reaffirmed as safe on numerous occasions by regulatory, health, and scientific authorities around the world, low-calorie sweeteners such as aspartame, when consumed in the context of a healthful diet and regular physical activity, can also be an effective weight management tool.. The International Food Information Council (IFIC) is committed to communicating science-based information and has communicated about the safety of aspartame for more than 25 years. The overwhelming consensus among qualified experts, based on decades of research, is that aspartame is a safe low-calorie sweetener for the general population and does not cause adverse health effects.. According to David Schmidt, President & CEO of IFIC, This latest EFSA review is one of a long string of studies, reviews, and ...
By Michael Biamonte CCN.. In the keynote address by the EPA, it was announced that in the United States in 2001 there is an epidemic of multiple sclerosis and systemic lupus. It was difficult to determine exactly what toxin was causing this to be rampant.. Now it appears that it is Aspartame. Marketed as Nutra Sweet, Equal, and Spoonful. When the temperature of this sweetener exceeds 86 degrees F, the wood alcohol in ASPARTAME converts to formaldehyde and then to formic acid, which in turn causes metabolic acidosis. Formic acid is the poison found in the sting of fire ants. The methanol toxicity mimics, among other conditions, multiple sclerosis and systemic lupus.. Many people are being diagnosed in error. Although multiple sclerosis is not a death sentence, Methanol toxicity is!. Systemic lupus has become almost as rampant as multiple sclerosis, especially with Diet Coke and Diet Pepsi drinkers. The victim usually does not know that the Aspartame is the culprit. He or she continues its ...
Aspartame is a sweetener made from two amino acids, phenylalanine and the excitotoxin aspartate. It should be avoided at all costs. Aspartame complaints accounts for approximately 70% of ALL complaints to the FDA. It is implicated in everything from blindness to headaches to convulsions. Sold under dozens of brand names such as NutraSweet and Equal, aspartame breaks down within 20 minutes at room temperature into several primary toxic and dangerous ingredients: ...
Cordell E Logan. Aspartame was discovered by accident in 1965 when James Schlatter, a chemist for G.D. Searle Co., was testing a drug for ulcers. It was approved for dry goods in 1981 and for carbonated beverages in 1983. However, in 1974 it was originally approved for dry goods, but neuroscience researcher Dr. John W. Olney put a hold on it. In 1985, Monsanto purchased G.D. Searle and made Searle Pharmaceuticals and NutraSweet Company separate subsidiaries.. The FDA reported that over 75% of adverse reactions to food additives are from Aspartame.. Aspartame is made up of aspartic acid (40%), phenylalanine (50%), and methanol (10%). Aspartic acid and glutamate are neurotransmitters. Too much of either one can kill certain brain neurons by allowing too much calcium to enter cells, which leads to an influx of free radicals that kill the cells. Excess of these amino acids can cross the blood brain barrier (BBB), especially in children. Problems include MS, ALS, memory loss, hormone imbalances, ...
Thanks Will! Oh yes, Rummy was very much involved.. To NovemberIsComing,. I thank you for your contribution. I do like to keep all perspectives in mind when I write, and I did research the claims by both the aspartame critics and those who promote/advocate for it. Your comment actually mirrors much of what I saw on the sites in support of aspartame. Almost to the letter.. Heres what I will agree with. Aspartame HAS been tested repeatedly over the years. Without a doubt. The question that arises as I stated within this article is the veracity of those tests. Seems they created more questions than answers, and the public record reflects at the minimum a cause for concern with how these tests were carried out. If the testing process has repeatedly come into question, I think it should make any rationally minded person hesitate to accept the company line that safety has been overwhelmingly affirmed.. Now, with regard to Monsanto, which by the way I mention ONCE at the very bottom of my post in an ...
What? That cant be right, you are likely thinking. It is.The methanol in aspartame affects the dopamine system of the brain causing addiction. Methanol, or wood alcohol, is classified as a severe metabolic poison.Aspartame is a dipeptide molecule produced by joining phenylalanine and aspartic acid. Aspartame itself does not occur…
Dr Betty Martini PhD, http://mpwhi.com/, Aspartame Makes Methanol to Formaldehyde, Special Studies Europe Likely to BAN Aspartame Toxic Sweetners, Second Segment, Dr Woodroe Monte MD, http://www.whilesciencesleeps.com/, Men Twice Gut Alcohol Dehydrogenase Women, Aspartame to Methanol to Formalde ...
Of course other foods (from diet yoghurts to low calorie jams) contain aspartame but diet drinks have the lions share and result in 80 per cent of consumption.. Chris Woollams, former Oxford University Biochemist and founder of CANCERactive, When the researchers did their first study, vested interests were happy to jump on the findings. This backfired. The researchers took all the comments onboard and repeated the research and got worse risk figures for aspartame. Needless to say, no action will be taken by people responsible for our health. In a meta-analysis produced in 2017, it was found that cans of fizzy soft drinks containing aspartame were associated with increased BMI and increased risk of diabetes, cardiovascular disease and strokes.. ...
Note: This information required a Freedom Of Information Act request to pry it from the reluctant hands of the FDA.. Nutrasweet (brand name for Aspartame) was not approved until 1981, in dry foods. For over eight years the FDA refused to approve it because of the seizures and brain tumors this drug produced in lab animals. The FDA continued to refuse to approve it until President Reagan took office (a friend of Searle) and fired the FDA Commissioner who wouldnt approve it. Dr. Arthur Hull Hayes was appointed as commissioner. Even then there was so much opposition to approval that a Board of Inquiry was set up. The Board said: Do not approve aspartame. Dr. Hayes OVERRULED his own Board of Inquiry. Shortly after Commissioner Arthur Hull Hayes, Jr., approved the use of aspartame in carbonated beverages, he left for a position with G.D. Searles Public Relations firm. Long-Term Damage. It appears to cause slow, silent damage in those unfortunate enough to not have immediate reactions and a reason ...
A. A brain tumor in adults can take many years or decades to become large and easily detectable. Aspartame couldnt have been the original cause of these brain tumors because it wasnt on the market long enough. However, it is known that certain less deadly brain tumors can transform into more deadly and larger forms in a shorter period of time. If aspartame was a brain tumor agent, that is what we would see first. Olney showed that in the most susceptible population group, there has been an enormous increase in these deadly types of brain tumors since within a few years after aspartame appeared on the market. Of course, there has been a corresponding decrease in the less deadly types of brain tumors during that time. That is why the *overall* brain tumor rate looks somewhat stable. So, whenever some government official talks about *overall* brain tumor rates, they clearly didnt read the Olney study ...
Dr. Bill Deagle says: Most people when asked how Aspartame is made do not have the first step of understanding. While an E.R. doctor and primary care physician in Augusta, GA in 1987 and 1988, I was told a number of interesting facts about the adjacent Aspartame factory. Bacteria with genes inserted generate a sludge which is centrifuged to remove the aspartame and many hundreds of contaminant organic and amino acids are present. We were told not to report illness or workers compensation issues for fear of being fired by the hospital, now the Augusta Regional Medical Center. Many of their employees presented with psychiatric, neuropathy conditions, chronic fatigue and organic cases of loss of cognitive function. This powder from the dried sludge was then transported for packaging in factories elsewhere in the US, before sale as Equal and now the myriad of names of this neurotoxin. Bill Deagle, M.D. ...
Save on Fiber With Aspartame (psyllium husk aspartame) prescription medication with Blink Pharmacy. Same pills. Lower prices. No coupon req.
To prevent the decline in sales, PepsiCo has replaced aspartame in diet pepsi, Caffeine Free Diet Pepsi and Wild Cherry Diet Pepsi with sucralose.
aspartame_and_sudden_death.htm Below are the real facts. You need more than the Secret Service to save his life. You have to educate President Trump and remove the Diet Coke because it contains aspartame, a chemical poison masquerading as an additive. As neurosurgeon Dr. Russell Blaylock said at a lecture: Understand the reactions from aspartame are not allergic but toxic like arsenic and cyanide.. I note in the picture above President Trumps skin is splotchy red. I dont know if this is the quality of the photo or if he has rosacea. Rosacea is usually genetic and incurable. http://scopeblog.stanford.edu/2015/03/12/researchers-identify-genetic-basis-for-rosacea/ Rosacea from aspartame is from the methanol and usually disappears when the victim abstains after a few months. This can also happen with Splenda or sucralose from the chlorine. When Charles Fleming died of methanol poisoning from aspartame he was on two rosacea drugs. From a rosacea support group here are people discussing ...
Mintel data* shared by stevia supplier PureCircle shows the number of global new product launches containing stevia grew by 10% in 2017, with stevia utilized in 28% of new products containing high intensity sweeteners, slightly ahead of aspartame - which featured in 25% of launches.
Diet drinks: The artificial sweetener aspartame, once listed by the Pentagon as a possible biochemical weapon, breaks down, when stored at 85 degrees for a week, into formaldehyde and other chemicals linked to brain tumors. Mattresses: Flame retardants and vinyl combine with room warmth and common fungi to create toxic gases that may cause headaches and dizziness - and asphyxiate babies as in Sudden Infant Death Syndrome. Deodorants: Contain suspected cancer-causing chemicals; perfumes and hairspray use industrial substances known to damage the liver, kidney, hormonal process and sperm count. Non-stick cookware: Nearly 100 percent of umbilical cords from newborns contain the chemical PFOA - used to make Teflon - which may alter hormone levels and cause birth defects. Plastic food containers: Zapping meals in the microwave heats and releases plastic chemicals, which seep into the food. The chemicals can harm fetal development ...
Carbonated beverage, low calorie, cola or pepper-type, with aspartame, contains caffeine from the USDA Nutrition Facts on RecipeTips.Com
Artificial sweeteners have been around for over 100 years, and people generally substitute sugar for artificial sweeteners for two basic reasons. One is to prevent weight gain and the other is to avoid the adverse effects of sugar is you are diabetic. Artificial sweeteners are known by many names but fall into three primary categories--saccharin SweetN Low), aspartame(Equal), and sucralose (Splenda). But what most people dont realize is that artificial sweeteners are chemicals that were never originally intended to be digested ...
Artificial sweeteners have been scrutinized intensely for decades. Critics of artificial sweeteners say that they cause a variety of health problems, including cancer. Thats largely because of studies dating to the 1970s that linked saccharin to bladder cancer in laboratory rats. Because of those studies, saccharin once carried a warning label that it may be hazardous to your health.. But according to the National Cancer Institute and other health agencies, theres no sound scientific evidence that any of the artificial sweeteners approved for use in the U.S. cause cancer or other serious health problems. And numerous research studies confirm that artificial sweeteners are generally safe in limited quantities, even for pregnant women. As a result of the newer studies, the warning label for saccharin was dropped.. Artificial sweeteners are regulated by the Food and Drug Administration (FDA) as food additives. They must be reviewed and approved by the FDA before being made available for ...
Dr. Cara Frankenfeld presented work on alteration of the human microbiome caused by artificial sweeteners at the Medical Nutrition: Nutrition and the Microbiome conference at the Boston Convention & Exhibition Center on March 30th, 2015.. Artificial Sweetener Consumption and Microbiome Profiles in 31 Adults Living in the United States. Cara L. Frankenfeld, Evan Lamb, Masoumeh Sikaroodi, Sarah Shoemaker and Patrick M. Gillevet. 1Global and Community Health, George Mason University (GMU), United States; 2Biology, GMU, United States and 3Microbiome Analysis Center, GMU, United States. The objective was to evaluate gut microbiome in relation to recent aspartame and Acesulfame-K artificial sweetener consumption. Thirty-one adults completed a four-day food record and provided a fecal sample on the fifth day. Fecal samples were analyzed for bacterial DNA using Multitag Pyrosequencing. Median values for bacterial abundance across non-consumers and consumers were compared. Overall bacterial abundance ...
Many sweeteners, and products like candy and chocolate that contain them, can come from GMO sources. Look for organic and non-GMO sweeteners, candy and chocolate products made with 100% cane sugar (to avoid the GM beet sugar), evaporated cane juice or organic sugar. And watch out for soy lecithin in chocolates and corn syrup in candies.. The sweetener aspartame is derived from GM microorganisms. It is also referred to as NutraSweet or Equal and is found in over 6,000 products, including soft drinks, gum, candy, desserts, yogurt, tabletop sweeteners, and some pharmaceuticals such as vitamins and sugar-free cough drops.. ...
If you thought that substituting sweeteners in place of sugar was better for you, you may want to read this first.. According to a new study by the University of Sydney, more than half of us are exceeding the World Health Organizations recommended daily intake of added sugars, which is at 10%.. Sugar can be found in lots of food and, in a bid to improve your sugar intake, you might reach for that artificial sweetener instead.. Artificial sweeteners are chemical substances that are used as an alternative to sugar to sweeten foods and beverages.. Whilst they add fewer calories to your diet than sugar, consuming sweeteners can lead to side affects, such as diarrhoea.. Each brand of artificial sweetener consists of chemical sweetening ingredients.. Equal is probably the most common artificial sweetener; this contains the sweetening ingredients of aspartame and acesulfame potassium.. The US National Cancer Institute found in 2006 that the consumption of aspartame does not increase in the risk of ...
Just 1/1000th the legally mandated dose of Aspartame, ingested for only 60 days, caused the highest incidence of brain tumor in rats, that any chemical ever tested at any dose, ever caused! The Aspartame dicarboxlic amino acid neural excito toxicity is also molecularly maximized, when given the two factors entioned above, (which also maximize the methyl alcohol toxic axis toxicity.) Medically well known examples of the extreme damage from these two factors and chemical classes, are Guam Parkinson disease, and Prince Edward Island shell fish: Domoic Acid poisoning, both of which have caused extreme neurological disease epidemics in Guam (And all around the Worlds Oceans), and Prince Edward Island, with lifelong neural sequelae, and also additional disease generations, occurring in those epidemics victims!(Just as Aspartame also always does!) For a clearer presentation of the even greater picture of Aspartames extreme toxicity, Plz get Ch 7 of Sweet Mystery in The Present Darkness: What ...
This legal-authority question has been asked of the attorney general, Patricia Madrid, whose office is presently preparing a formal opinion as to whether our states boards can legitimately challenge a Food and Drug Administration-approved product like aspartame. The FDAs approval was flawed, if not corrupt, to begin with, as was made clear in the September 2005 Sun article Rumsfelds Disease. Therefore it seems incomprehensible that such a faulty FDA approval could not be questioned by a state board having heard a significant amount of evidence thus far. But this is just what corporate lawyers representing the Japanese firm Ajinomoto, the worlds largest aspartame manufacturer, would like the boards and the attorney general to believe. Ajinomoto is joined in this legal effort by an industry front group, the Calorie Control Council. They have both hired high-powered lawyers to silence the boards on the grounds that aspartame is safe and that, besides, no one but the FDA, Congress and the ...
Concentrated Low Calorie Soft Drink with Vegetable Extracts with Sweeteners Post-Mix Syrup. Water, Colour (Caramel E150d), Phosphoric Acid, Sweeteners (Aspartame, Acesulfame K). Natural Flavourings including Caffeine, Acidity Regulator (Sodium Citrate), Preservative (Sodium Benzoate), Antifoaming Agent (Dimethyl Polysiloxane). Contains a Source of Phenylalanine.. ...
Phenylalanine ammonia lyase (EC 4.3.1.24) is an enzyme that catalyzes a reaction converting L-phenylalanine to ammonia and trans-cinnamic acid. Phenylalanine ammonia lyase (PAL) is the first and committed step in the phenyl propanoid pathway and is therefore involved in the biosynthesis of the polyphenol compounds such as flavonoids, phenylpropanoids, and lignin in plants. Phenylalanine ammonia lyase is found widely in plants, as well as some yeast and fungi, with isoenzymes existing within many different species. It has a molecular mass in the range of 270-330 kDa. The activity of PAL is induced dramatically in response to various stimuli such as tissue wounding, pathogenic attack, light, low temperatures, and hormones. PAL has recently been studied for possible therapeutic benefits in humans afflicted with phenylketonuria. It has also been used in the generation of L-phenylalanine as precursor of the sweetener aspartame. The enzyme is a member of the ammonia lyase family, which cleaves ...
Refined white sugar is considered to be one of the harmful ingredients in the modern diet. It can contribute to all sorts of diseases from diabetes to fatty liver to stress.. Get the Free Tracker App to find a Nintendo Switch in Stock. Nearly two decades ago, an artificial sweetener had been introduced under the brand name of Splenda. The artificial sweetener was promoted as a healthier alternative to white sugar but new research has found that Splenda is increasing the risk for leukemia. A recent study published in International Journal of Occupational and Environmental Health has shown a link between Splenda and blood cancer.. The study involved more than 800 mice who were fed high doses of Splenda or Sucralose daily throughout their lives. It was found that the artificial sweetener can contribute in developing leukemia and other blood cancers. The latest study somehow supports the findings of many previous studies that also claimed that artificial sweetener can cause cancer.. In 2013, ...
http://news.therawfoodworld.com/artificial-sweeteners-muck-gut-lower-human-microbiome/ (TRFW News) Recent studies have found that artificial sweeteners aren t just bad for weight gain, headaches, and heightening sugar cravings they re also renowned for mucking up the gut and disrupting the human microbiome (1). Artificial sweeteners lower microbiome function Diabetics have been using artificial sweeteners (also referred to as non-caloric artificial sweeteners or NAS) for years in the conquest to eliminate refined and natural sugars in their diet to support their blood sugar (1 ...
http://news.therawfoodworld.com/artificial-sweeteners-muck-gut-lower-human-microbiome/ (TRFW News) Recent studies have found that artificial sweeteners aren t just bad for weight gain, headaches, and heightening sugar cravings they re also renowned for mucking up the gut and disrupting the human microbiome (1). Artificial sweeteners lower microbiome function Diabetics have been using artificial sweeteners (also referred to as non-caloric artificial sweeteners or NAS) for years in the conquest to eliminate refined and natural sugars in their diet to support their blood sugar (1 ...
Humans have always had a fondness for sweets. During the world wars, saccharose, (common sugar) was obtained from sugar cane or beets. Saccharin, the first artificial sweetener, was synthesized in 1879, and was popular during the world wars due to its low production cost. After World War II, sugar became more affordable, and since the 1950s, the reason for using saccharin shifted to calorie reduction. However, the bitter after-taste of saccharin produced a growing need for improved taste of calorie-reduced substances. Artificial sweeteners are classified as first generation (saccharin, cyclamate and aspartame) and new generation (acesulfame-K, sucralose, alitame and neotame). Cyclamate was introduced in the 1950s, but the Food and Drug Administration (FDA) banned it from all dietary foods in 1970, due to suspicion that it induced cancer in experimental animals. Cyclamate is still used in other countries, especially in combination with other sweeteners. Aspartame (NutraSweet) was approved by the ...
In the Israeli experiment, 10-week-old mice were fed a daily dose of aspartame, sucralose or saccharin. Another cluster of mice were given water laced with one of two natural sugars, glucose or sucrose. After 11 weeks, the mice receiving sugar were doing fine, whereas the mice fed artificial sweeteners had abnormally high blood sugar (glucose) levels, an indication that their tissues were having difficulty absorbing glucose from the blood. Left unchecked, this glucose intolerance can lead to a host of health problems, including diabetes and a heightened risk of liver and heart disease. But it is reversible: after the mice were treated with broad-spectrum antibiotics to kill all their gut bacteria, the microbial population eventually returned to its original makeup and balance, as did blood glucose control.. These bacteria are not agnostic to artificial sweeteners, says computational biologist Eran Segal of the Weizmann Institute of Science in Rehovot, Israel, one of the two scientists ...
Studies done with animals have shown that artificial sweeteners cause weight gain. A sweet taste causes insulin to be produced. This will store some of the sugar in the blood in tissues, including fat. With artificial sweeteners, the amount of sugar in the blood does not increase. This means that there will be too little sugar in the blood. This is known as hypoglycemia. On the next meal, more food will be eaten to get the blood sugar level back to normal values. After a while, rats given sweeteners have steadily increased the amount of calories. This increased body weight, and adiposity (fatness). The natural response to eating sugary foods is to eat less at the next meal and to use some of the extra energy to warm the body after the meal. When using artificial sweeteners, this effect is lost gradually.[2] ...
When sugar-free beverages first became available, I was skeptical that they could really taste as good as the real thing. I quickly changed my mind. In fact, it seemed to me that the sugar-free versions actually tasted better than the real thing.. It seemed like a no-brainer. Sugar-free beverages had no calories and tasted better-maybe there is such a thing as a free lunch. Obviously, many people who also wanted to lose weight made the same switch. Were we right about artificial sweeteners?. Although short-term studies suggest that switching from sugar to no-calorie sweeteners can help, other research suggests it may actually promote weight gain. Writing in the December 2011 Harvard Health Letter, noted obesity researcher Dr. David Ludwig explores the possible connection between sugar substitutes and weight gain.. The FDA has approved six calorie-free sweeteners: acesulfame, aspartame, neotame, saccharin, Stevia, and sucralose. They are hundreds to thousands of times sweeter than table ...
The Weizmann Institutes Eran Elinav, Ph.D, who headed the research revolving around this study, believes that the mechanism behind this may be changes in the composition of gut microbiota brought on by artificial sweeteners. Even though artificial sweeteners do not contain sugar, the belief from the authors of this study is that they still affect the bodys ability to utilize glucose, leading to glucose intolerance, which in turn leads to adult-onset diabetes and metabolic syndrome.. The study itself involved giving mice water laced with three common artificial sweeteners in equivalent amounts to those permitted by the FDA, then repeating the process with different types of mice and amounts of sweeteners. In all cases, the mice developed glucose intolerance. The conclusion that gut microbiota played a role in this intolerance was based off of a previous hypothesis. In order to test this, the glucose intolerant mice were given antibiotics to wipe their microbiota, which resulted in a full ...
Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota Noncaloric artificial sweeteners (NASs) are popular because of their low caloric intake and perceived health benefits for weight loss and normalization of blood sugar levels. Artificial sweeteners have been increasingly introduced as an additive into common foods as an alternative to high-caloric sugars. However, increased consumption has coincided with a dramatic increase worldwide in obesity and diabetes epidemics.
The next time you drink diet soda or eat low-fat yogurt, look closely at the labels; the sweetness you taste may be due to the artificial sweetener...
Artificial sweeteners receive tons of attention in the nutrition world and. To produce the final product often found in soft drinks and other diet foods, of our system, but I think the most important is to just stop them coming in. Reducing sugar in your diet can help you drop pounds, improve your. Though they dont contribute calories, artificial sweeteners are not. In addition to diet drinks and those little colored packets, artificial sweeteners be lurking in foods you dont suspect, including gum,
Global Artificial Sweeteners Market: Dynamics. Growth of the global artificial sweeteners market is mainly bound to various micro-economic and macro-economic factors. The report states that the global artificial sweeteners market is significantly driven by increasing preference for healthy food products.
How to Avoid Artificial Sweeteners. For most people, avoiding artificial sweeteners should not be a concern. But for some - especially pregnant women or people with metabolic disorders - avoiding artificial sweeteners is an important way to...
The never-ending debate about the fattening effects of artificial / non-nutritive sweeteners is probably going to kick up a notch once the rest of the web has gotten wind of the results of this soon-to-be published paper. Is it possible that one of the allegedly harmless sugar alcohols is worse than the the synthetic bad guys? The results of the study at hand allow for A LOT of speculations...
There are four main artificial sweeteners on the market today - saccharin, aspartame, sucralose, and stevia - each has their own positives and negatives you need to know about.
New Canadian research published Monday suggests that artificial sweeteners, such as aspartame, sucralose and stevia, may be doing more harm than good.
If there is a problem with a food product that means it should not be sold, then it might be withdrawn (taken off the shelves) or recalled (when customers are asked to return the product). The FSA issues Product Withdrawal Information Notices and Product Recall Information Notices to let consumers and local authorities know about problems associated with food. In some cases, a Food Alert for Action is issued. This provides local authorities with details of specific action to be taken on behalf of consumers. ...
Can be found in over 6,000 processed products which line our grocery shelves from puddings, sodas, yogurts, ice creams and even in childrens vitamins…
Did you find that the lemonade made with artificial sweetener was sweeter than that made with sugar? Did the original sugar lemonade taste almost as sour and bitter as the pure lemon juice?. Artificial sweeteners are synthetic compounds designed to produce the intense sweet taste you observed in the artificially sweetened lemonade. In fact, the sweetness of artificial sweeteners is many times that of sugar. This means that if you add equal quantities of sugar and an artificial sweetener, the drink with the artificial sweetener will taste sweeter.. If you completed the Extra challenge, you may have seen that it took several teaspoons of sugar to equal the sweetness of the artificial sweetener. Splenda is 600 times sweeter than sugar and saccharine, found in Sweetn Low, is 300 to 500 times sweeter. In the lemonade some of the sweetness is masked by the sourness of the lemon so you will not need to add 100 more teaspoons of sugar to get the same sweetness as one-quarter teaspoon of ...
Ever had any of the Wrigleys Orbit chewing gum? Its darn good and pretty much different than any other gum out there. If you notice the bold ingredient on the side says CONTAINS PHENYLALANINE. So I decided to find out what exactly is in that stuff. According to Wikipedia Phenylalanine is an amino acid and comes in either the D- or the L- form. It is used as a sweetener in prepared foods, like soft drinks. Due to phenylketonuria [a metabolic disorder], products containing aspartame usually have a warning label that they contain phenylalanine, in compliance with U.S. FDA guidelines. This disease only occurs in less than 1 in 15,000 persons. On the positive note cockatoo writes about the sexual enhancing side effects of Phenylalanine, and weight loss aid by suppressing your appetite. So if you dont have PKU go on and enjoy it. It has no side effects and not cancerous according to tracy, Although do watch out for stuff that contains Aspartame. They are a dangerous combo. ...
Its funny how people will use aspartame or the other diet sweeteners, and consume food chemicals that have been proven to be harmful to good health, yet they seem more cautious when using a nutritional supplement.. That said, it is always best to be cautious when introducing new food regimens and new supplements, especially if you have special circumstances or health weaknesses.. You might want to monitor taking Spirulina if you are PKU because it contains the amino acid phenylalanine; albeit, it is a natural form of the amino acid, unlike the manufactured form of phenylalanine found in aspartame.. If you start using Spirulina, check with your doctor if you are taking anti-coagulation medicine, and if you are pregnant or nursing, you might want to stop using Spirulina at this time. Remember, Spirulina is a powerful protein source, gram to gram, and your body might be sensitive to the amino acid content.. Personally, I love Spirulinas health benefits, and feel that it is a wonderful addition to ...
Splenda is not Splendid Compiled by Ingri Cassel Since we have been sharing about the dangers of diet products containing aspartame and encouraging people to read The Artificially Sweetened Times [http://www.vaclib.org/news/astimes.htm], many have asked us about Splenda, thinking that sucralose doesnt have the same problems as aspartame, saccharine and refined white sugar. The following articles address the problems with Splenda according to a biochemist, a researcher and one mans personal experiences with the chemically altered sweetener. Splenda, the brand name for sucralose, is produced by chlorinating sugar (sucrose). This involves chemically changing the structure of the sugar molecules by substituting three chlorine atoms for three hydroxyl group atoms. Sucralose was discovered in 1976 by researchers working under the auspices of Tate & Lyle Ltd., a large British sugar refiner. In 1980, Tate & Lyle arranged with Johnson & Johnson, the worlds largest health care company, to develop ...
In this review, aspartame and Ala-Gln are produced using different industrial processes, the manufacturing processes of these two dipeptides are compared to clarify the characteristics of each procedure. The functions and applications of l-α-dipeptides (dipeptides) have been poorly studied compared with proteins or amino acids. Only a few dipeptides, such as aspartame (l-aspartyl-l-phenylalanine methyl ester) and l-alanyl-l-glutamine (Ala-Gln), are commercially used. This can be attributed to the lack of an efficient process for dipeptide production though various chemical or chemoenzymatic method have been reported. Recently, however, novel methods have arisen for dipeptide synthesis including a nonribosomal peptide-synthetase-based method and an l-amino acid α-ligase-based method, both of which enable dipeptides to be produced through fermentative processes. Since it has been revealed that some dipeptides have unique physiological functions, the progress in production methods will undoubtedly
Carbonated water, caramel color, phosphoric acid, sodium saccharin, potassium benzoate (to protect taste), natural flavors, citric acid, caffeine, potassium citrate, Aspartame, dimethylpolysiloxane. Phenylketonurics: Aspartame contains phenylalanine ...
TY - JOUR. T1 - Microbial aspartase and its activity on deamination of L-aspartyl-L-phenylalanine methyl ester. AU - Chung, Wonyoon. AU - Goo, Yang Mo. PY - 1988/6. Y1 - 1988/6. N2 - Examination of many microorganisms and soil isolates for the activity of aspartase proved that R. rubra, G. suboxydans, A. versicolor, P. purpurogenum, E. coli, Ps. aeruginosa, A. gigantus, A. unguis, A. parasiticus and a soil isolate(S-90) had high activity of aspartase. Comparision of the activity of the aspartase by cell free extracts of these micro-organisms with the activity of the enzyme catalyzing the deamination of aspartame by the same cell free extracts showed similar kinetic characteristics. The aspartase existing in the cell free extracts seemed to catalyze the deamination of aspartame, too.. AB - Examination of many microorganisms and soil isolates for the activity of aspartase proved that R. rubra, G. suboxydans, A. versicolor, P. purpurogenum, E. coli, Ps. aeruginosa, A. gigantus, A. unguis, A. ...
If you keep the total amount of glutamate in your body under control, you can prevent neurologic symptoms. One way you can do this is by eliminating gluten and casein from your diet. You also want to eliminate glutamate and anything that sounds like that, and aspartate and anything that sounds like that, from your supplements.. Glutamine is a frequently recommended supplement, but glutamate and glutamine change back and forth into each other. This means that the administration of glutamine, say for gastro intestinal support, actually increases the level of glutamate.. There is a neurotransmitter, which opposes glutamate, which has a calming effect. This is GABA, gamma amino butyric acid. It is an inhibitory neurotransmitter. Glutamate should be able to convert into GABA.. Glutamate is acted on by the enzyme glutamic acid decarboxylase (GAD), but several factors may interfere with this conversion, and you get stuck at glutamate.. GABA is the neurotransmitter involved with this function. GABA is ...
If you need to delete a post, please follow the tutorial on the contact page on this link or use the yellow icon ASK TO REMOVE THIS POST in the bottom of the original post ...
In the paper Diet Coke and Mentos: What is really behind this physical reaction? by Tonya Shea Coffey the findings of the Mythbuster teams are largely confirmed.. By measuring contact angles it was shown that aspartame and potassium benzoate reduce the surface tension of water. Aspartame is a winner, and as an extra benefit clean up is much easier with Diet Coke than sugared Coke. The amount of caffeine however is too low to have any effect. The roughness of the Mentos surface was studied with special microscopes (see picture below). Fruit Mentos have smooth patches, but the coating is not uniform and contrary to the Mythbuster experiment normal Mentos and Fruit Mentos performed equally well with regards to foam formation. The roughness of the Mentos surface was inbetween that of rock salt and the Life savers which suggests that roughness is not a single factor determining the reaction. The Mentos surface is covered with gum arabic which reduces surface tension, and experiments showed that ...
The #1 Childrens Vitamin Brand in the US contains ingredients that most parents would never intentionally expose their children to, so why arent more opting for healthier alternatives? Kids vitamins are supposed to be healthy, right? Well then, whats going on with Flintstones Vitamins, which proudly claims to be Pediatricians #1 Choice? Produced by the global…
Fibromyalgia and Liver Toxicity Located on the correct side of the abdomen, the liver is first to course of the nutrients delivered by means of the blood stream. WhaleShark Media After studying about the benefits of therapeutic massage therapy from a earlier GoMassage consumer, WhaleSharkMedia contacted GoMassage in pursuit of a creative strategy to thank their workplace employees. Who can practice therapeutic massage in Hollywood? Find the right massage therapy in Hollywood FL that matches your Holistic well being care wants! Professional pores and skin care helps expose the pores and skin to useful nutrients and improve the cellular regeneration process, so youll feel and appear wholesome. Silymarin helps the cells produce a strong antioxidant often known as glutathione. Cysteine, glycine and glutamine (glutamic acid) combine to make glutathione. When the temperature of Aspartame exceeds 86 levels F, the wooden alcohol in Aspartame is changed into formaldehyde after which into formic acid. ...
Today however, on waking, and getting the usual fat lip feeling, i saw my eye was slightly swollen, but the whole of my body was covered in huge hives , which has not happened to this extent before , and instead of fading slowly through the day, they became more itchy, and red marks appeared in the pinky coloured hives . I felt as if i was on fire, so went to Primecare, but got the same answers.... it could last weeks, months, or years . My hospital records show id had a skin test, but on enquiring why it says that, i was told theres no point having a skin test ....i said i wasnt asking for one, i was asking why it says ive had one just to be blah-blahed and ignored ...I really feel at the end of my tether , and working with someone who thinks its funny to tell my workmates to avoid me as i have scabies , is wearing thin . I have found out the hard way to avoid Ibuprofen, as i had a bad reaction to it, and my throat started to swell, and Anadin Extra, which caused the worst facial ...
Supporting: 1, Mentioning: 73 - The rapid increase in the prevalence of obesity worldwide has been partially attributed to the overconsumption of added sugars. Recent guidelines call for limiting the consumption of simple sugars to less than 10% of daily caloric consumption. High intensity sweeteners are regulated as food additives and include aspartame, acesulfame-k, neotame, saccharin, sucralose, cyclamate and alitame. Steviol glycosides and Luo Han Guo fruit extracts are high intensity sweeteners that are designated as generally recognized as safe (GRAS). Commonly used non-caloric artificial sweeteners may have unfavorable effect on health including glucose intolerance and failure to cause weight reduction. The nutritive sweeteners include sugar alcohols such as sorbitol, xylitol, lactitol, mannitol, erythritol, trehalose and maltitol. Naturally occurring rare sugars have recently emerged as an alternative category of sweeteners. These monosaccharides and their derivatives are found in nature in
Cell Metabolism, 2016 July 12;24(1): 75-90. Both flies and mice have the same pathways which are triggered by sucralose (Splenda) to make the body think it is starving and increase the desire to eat. Wang explains that a sweet taste without any calorie content creates the sensation of fasting and increases calorie consumption. It also promotes hyperactivity, insomnia, and glucose intolerance. All these problems are reversible by taking away the sweeteners.. Will it do the same for humans? Well, we do have genetic, hormonal, and neurotransmitter pathways very similar to both flies and mice.. NOTE: If you use any of the artificial sweeteners, experiment on yourself and see if you are hungrier at lunch when you put artificial sweetener in your breakfast coffee or when you use real sugar.. NOTE: Artificial sweeteners like sucralose, saccharin, and aspartame are not acceptable on the Feingold, the Paleo, or the Failsafe diets. They should probably be avoided by everybody else, too, as much as ...
Artificial sweeteners are sugar substitutes that have a sweet taste. There are many different types of sweeteners available. Some are found in pre-packaged foods and drinks and some may be purchased to add to foods like coffee and tea, or for baking and cooking. Read on to learn more about artificial sweeteners, where they can be found and if they may be right for you.
The safety of aspartame has been studied since its discovery.[17] Aspartame is one of the most rigorously tested food ... Aspartame is rapidly hydrolyzed in the small intestines. Even with ingestion of very high doses of aspartame (over 200 mg/kg), ... Main article: Aspartame controversy. Aspartame has been found to be safe for human consumption by more than ninety countries ... The PBOI concluded aspartame does not cause brain damage, but it recommended against approving aspartame at that time, citing ...
... foods containing aspartame must carry ingredient panels that refer to the presence of "aspartame or E951" and they must be ... Another common source of phenylalanine is anything sweetened with the artificial sweetener aspartame, such as diet drinks, diet ... Accordingly, all products in Australia, the U.S. and Canada that contain aspartame must be labeled: "Phenylketonurics: Contains ... L-Phenylalanine is produced for medical, feed, and nutritional applications, such as aspartame, in large quantities by ...
"Aspartame". UK FSA. June 17, 2008. Retrieved April 20, 2011. "Aspartame". EFSA. Retrieved April 20, 2011. "Aspartame". Health ... "Food Additive Approval Process Followed for Aspartame". Food Additive Approval Process Followed for Aspartame GAO/HRD-87-46 ( ... aspartame, which was marketed as the brand NutraSweet, in 1983. Aspartame has been the subject of controversy, most notably in ... Aspartame has been deemed safe for human consumption by regulatory agencies in their respective countries, including the U.S. ...
Hattan, David (2 February 2010). "Aspartame". Snopes. Retrieved 25 March 2014. "The Mouse that Roared: Health Scares on the ... and statements about the toxicity of methanol produced by aspartame metabolism rely on ignoring the small amounts produced by ... In 1998 an email began circulating claiming that aspartame, an artificial sweetener, caused many chronic diseases, including ...
uses the slogan "Kick Aspartame" to promote their sugar-free and aspartame-free products. In 2010, entrepreneur Jay Klein aimed ... PUR Gum is a brand of aspartame-free gum produced by The PUR Company Inc. and founded in 2010 by Jay Klein in Toronto, Ontario ... CS1 maint: discouraged parameter (link) "Aspartame-free gum makes inroads in first year". The Canadian Jewish News. 2011-11-17 ... CS1 maint: discouraged parameter (link) Watson, Elaine (2013-08-19). "Kicking aspartame? The rise and rise of PÜR Gum". ...
It contains aspartame. Trident White no longer contains Recaldent (casein phosphopeptide-amorphous calcium phosphate), a milk- ... It is also sweetened with sorbitol, Mannitol, Aspartame, Sucralose and Acesulfame potassium. Trident White (formerly Trident ... aspartame, phenylalanine, and other sweeteners. It also contains Gelatin and hence is not suitable for vegans or those who ...
Cook, Winifred I. (1983-05-31). "Aspartame is being used". The Central New Jersey Home News. p. 4. Retrieved 2020-09-25. ... Crystal Light is sweetened with a combination of aspartame, acesulfame potassium, Sucralose, and/or sugar depending on the ...
He was involved in the evaluations of aspartame when it was first being introduced as an artificial sweetener; he initially ... Rovner, Sandy (1 July 1983). "Aspartame: Sweet and Sour". Washington Post. "Hormone Pills Aid Sleep". The New York Times. ...
... relies on aspartame, which has been suggested to pose health concerns. Aspartame is one of the most intensively scrutinized ... "Coke Beginning Aspartame Use". New York Times. August 18, 1983. p. D4. Ordoñez, Franco (March 3, 2005). "Suit Alleges Deceit in ... After Diet Rite cola advertised its 100 percent use of aspartame, and the manufacturer of NutraSweet (then G. D. Searle & ... Diet Coke was sweetened with aspartame, an artificial sweetener, after the sweetener became available in the United States in ...
1965 Aspartame Aspartame is the name for an artificial, non-saccharide sweetener, aspartyl-phenylalanine-1-methyl ester; that ... Aspartame was discovered in 1965 by James M. Schlatter, a chemist working for G.D. Searle & Company. Schlatter had synthesized ... "Desert Island Discs". BBC Radio 4. "History". The Aspartame Information Service. Landolt, Arlo U. (1968). "A New Short-Period ... aspartame in the course of producing an anti-ulcer drug candidate. 1965 Pulsating white dwarves A pulsating white dwarf is a ...
Aspartame controversyEdit. Main article: Aspartame controversy. In 1998 an email began circulating claiming that aspartame, an ... "Aspartame". Snopes. Retrieved 25 March 2014.. *^ "The Mouse that Roared: Health Scares on the Internet". Food Insight. May- ... and statements about the toxicity of methanol produced by aspartame metabolism rely on ignoring the small amounts produced by ...
... oversaw the development of the artificial sweetener aspartame; developed nontoxic processes to create food colorings and remove ... development of the artificial sweetener aspartame; development of nontoxic processes to create food colorings and remove ...
Other examples are aspartame and carnosine. Pyrimidine dimers are formed by a photochemical reaction from pyrimidine DNA bases ...
Aspartame binds to the same receptor. Water solutions of neotame, that are equivalent in sweetness to sucrose water solutions, ... Unlike aspartame, neotame doesn't form diketopiperazines via intra-molecular cyclization due to its N-alkyl substitution with 3 ... Neotame, also known by the trade name Newtame, is a non-caloric artificial sweetener and aspartame analog by NutraSweet. By ... Neotame is formally a secondary amine of 3,3-dimethylbutanal and aspartame. Latter is a dipeptide of phenylalanine and aspartic ...
"Material Safety Data Sheet: Aspartame" (PDF). Spectrum. Archived from the original (PDF) on 2016-12-26. "Safety (MSDS) data for ...
Aspartame Aspartame controversy Sugar substitute "Archived copy". Archived from the original on 2006-12-06. Retrieved 2006-12- ... Canderel is a brand of artificial sweetener made mainly from aspartame. Canderel is marketed by The Merisant Company, a global ... It is the leading aspartame-based sweetener in France (where it was launched in 1979) and the United Kingdom (since 1983). ... "Canderel tablets" ingredients: lactose, aspartame, acesulfame potassium, leucine, cross-linked CMC, flavouring. Canderel is ...
In that same year, aspartame was discovered. Aspartame was introduced into the Assugrin brand as Assugrin Gold. In 1987, orange ... Business Wire (September 27, 2007) The Worldwide Artificial Sweeteners Market - Aspartame, Acesulfame Potassium, Saccharin and ...
That was replaced by NutraSweet-brand aspartame. Around the time of the 2005 redesign, acesulfame potassium was added as a ... Aspartame Acesulfame potassium Acacia Natural flavors Glycerol ester of wood rosin Carob bean gum North America (Mexico): ...
Aspartame. *Birch sap. *L-Xylulose reductase. *Xylonic acid. References[edit]. *^ Safety data sheet for xylitol from Fisher ...
Aspartame. *Aspartame-acesulfame salt. *Dulcin. *Glucin. *Hydrogenated starch hydrolysates. *Neohesperidin dihydrochalcone. * ...
... is often used with aspartame in diet carbonated soft drinks, so some sweetness remains should the fountain syrup be ... stored beyond aspartame's relatively short shelf life. In its acid form, saccharin is not water-soluble. The form used as an ... to be widely used in the United States and is now the third-most popular artificial sweetener behind sucralose and aspartame. ...
... the artificial sweetener aspartame has two enantiomers. L-aspartame tastes sweet whereas D-aspartame is tasteless. Odor: R-(-)- ...
Bradshaw, Peter (April 20, 2016). "Captain America: Civil War review - an aspartame rush". The Guardian. Archived from the ...
Aspartame was also discovered accidentally when chemist Schlatter tasted a sweet substance that had stuck to his hand. ... Gratzer, Walter (28 November 2002). "5. Light on sweetness: the discovery of aspartame". Eurekas and Euphorias: The Oxford Book ...
Aspartame, commonly known by the brand name NutraSweet, is one of the most commonly used artificial sweeteners. The 1982 ... The newer aspartame-free drinks can also be safely consumed by phenylketonurics, because they do not contain phenylalanine. ... Today, at least in the United States, "diet" is nearly synonymous with the use of aspartame in beverages. Neotame and advantame ... After further studies in the 1980s linked saccharin to cancer as well, most manufacturers switched to aspartame in 1983. By the ...
Others, such as aspartame and sodium saccharin, have much larger variation. Even some inorganic compounds are sweet, including ... New World monkeys do not find aspartame sweet, while Old World monkeys and apes (including most humans) all do. Felids like ... I. Why Does Alitame Taste Sweet in all Prosimians and Simians, and Aspartame only in Old World Simians?" (PDF). Chemical Senses ... Saccharin, cyclamate, aspartame, acesulfame potassium, sucralose, alitame, and neotame are commonly used.[citation needed] A ...
... 's effervescent tablets contain small quantities of aspartame (phenylalanine). Berocca ran a series of television ...
L-aspartame tastes sweet whereas D-aspartame is tasteless. Odor: R-(-)-carvone smells like spearmint whereas S-(+)-carvone ... Examples of this selectivity include: Flavour: the artificial sweetener aspartame has two enantiomers. ...
An allegation was that the G. D. Searle & Company was trying to bring aspartame to market and get it approved by the U.S. Food ... Metzenbaum was skeptical of corporations and agencies promoting aspartame. ... that aspartame was safe for most people. Of the report, Metzenbaum said, "I wish that this [JAMA] report could ease my concerns ... Senate heard testimony relating to an amendment by Metzenbaum that would require the quantity of aspartame in a product to be ...
... soda is a zero-calorie, aspartame-sweetened carbonated soft drink canned and distributed by the ... Canfield's Diet Chocolate Fudge by this time sweetened with aspartame. When Chicago Tribune reporter Bob Greene reviewed the ...
The safety of aspartame has been studied since its discovery.[17] Aspartame is one of the most rigorously tested food ... Aspartame is rapidly hydrolyzed in the small intestines. Even with ingestion of very high doses of aspartame (over 200 mg/kg), ... Main article: Aspartame controversy. Aspartame has been found to be safe for human consumption by more than ninety countries ... The PBOI concluded aspartame does not cause brain damage, but it recommended against approving aspartame at that time, citing ...
aspartame: an artificial sweetener used in place of sugar because it has few calories. its sold in stores under the brand ... What is aspartame?. ANSWER Aspartame: An artificial sweetener used in place of sugar because it has few calories. Its sold in ...
Aspartame (NutraSweet, Equal, etc) is one of the most common artificial sweeteners in use today. Find out what we know about ... Does Aspartame Cause Cancer?. What is aspartame? Aspartame is an artificial sweetener, sold under brand names such as ... Aspartame (see FAQ section): www.efsa.europa.eu/en/topics/topic/aspartame. EFSA Explains the Safety of Aspartame: www.efsa. ... Is aspartame regulated?. In the United States, artificial sweeteners such as aspartame are regulated by the FDA. These products ...
There is still a camp of substantial size insisting aspartame is deadly. Of course, its widely sold, and still FDA-approved, ... There is one group of people for whom aspartame is undisputedly dangerous, however: phenylketonurics. ... I covered aspartame, the sometimes-maligned intense artificial sweetener. ... Fully 11% of aspartame is methanol -- 1,120 mg aspartame. in 2 L diet soda, almost six 12-oz cans, gives 123 mg. methanol (wood ...
Controversies with aspartame]" (2003). Med Pregl 56 Suppl 1: 27-9.. *↑ "Aspartame and seizure susceptibility: results of a ... I. Aspartame hemihydrate." (Mar 2001). Pharm Res 18 (3): 267-73.. *↑ Roberts HJ (2004). "Aspartame disease: a possible cause ... Aspartame disease. H.J. Roberts, MD, coined the term "aspartame disease" in a book filled with over 1,000 pages of information ... Aspartame in bottled liquids breaks down after six to eight weeks of shelf life. Aspartames major decomposition products are ...
Aspartame is an artificial sweetener used in many foods. Its health effects are highly controversial, and this article examines ... Claim: Aspartame Causes Weight Gain. As a low-calorie sweetener, aspartame is commonly consumed by people who want to enjoy the ... Claim: Aspartame Causes Seizures. A few small studies have investigated the effects of aspartame on seizures. Most of them ... Aspartame is an artificial sweetener, often denoted as E951.. Originally sold under the brand name NutraSweet, aspartame was ...
Aspartame is an intense sweetener, approximately 200 times sweeter than sugar, which has been used in soft drinks and other low ... Since aspartame is also a source of phenylalanine, all food products containing aspartame are clearly labelled to indicate the ... Aspartame was first approved in the UK in 1982 following the review of its safety by the UKs Committee on Toxicity, Consumer ... Aspartame is an intense sweetener, approximately 200 times sweeter than sugar, which has been used in soft drinks and other low ...
FDA had received about consumption of aspartame-containing products. The request followed an increase in aspartame-related ... aspartame and onset of symptoms often were incomplete because aspartame consumption was part of the daily routine. ... where the possibility of aspartame use leading to illness received particularly extensive press coverage. Although aspartame- ... As far as is known, complaints, such as those reported in this analysis as being related to aspartame use, have not been ...
Aspartame Chemical Formula: Synonyms. L-alpha-aspartyl-L-phenylalanine methyl ester Description. White powder. Aspartame is ... In acidic solutions at high temperatures, aspartame degrades and looses its sweetness. aspartame: InChI=1/C14H18N2O5/c1-21-14( ... Aspartame is a low-calorie sweetener used in many foods and drinks. Because it is between 160 and 200 times sweeter than sugar ... A typical 12 ounce low-calorie soft drink will have 180 milligrams of aspartame in it. ...
Aspartame is a low-calorie, intense artificial sweetener. It is a white, odourless powder, approximately 200 times sweeter than ... Background on aspartame:. 1. What is aspartame?. Aspartame is a low-calorie, intense sweetener which is approximately 200 times ... What happens to aspartame in the body once it is ingested?. Following ingestion, aspartame breaks down in the gut into its ... 2. In which food products is aspartame used?. Aspartame is authorised in the EU for use as a food additive to sweeten a variety ...
What is aspartame?. Aspartame (L-aspartyl-L-phenylalanine methyl ester) (E 951) is a dipeptide of L-phenylalanine methyl ester ... Is aspartame representing a health risk and where the EFSA conclusions of its previous risk evaluation of aspartame modified?. ... and concluded that aspartame consumption was not of safety concern at the current aspartame and its degradation products ... 40 mg/kg bw/day for aspartame). In calculating a safe level of aspartame exposure (based on plasma phenylalanine concentrations ...
I have heard so much controversy regarding aspartame (found in diet drinks) and MS. I was wondering what thoughts anyone had on ... and specifically told me to be careful of aspartame...I dont recall why. Thats all I know about the aspartame/MS thing. I ... Aspartame is a toxin, its poison as far as Im concerned and although I was not a big diet coke fan, it was the only soda I ... The MS/Aspartame link is bogus. You can read about it at Snopes.com under their scientific urban legends. If you choose to ...
... foods that contain aspartame are required to list aspartame among the ingredients, include the amount of aspartame per serving ... Aspartame is around 180 to 200 times as sweet as sucrose (table sugar). Due to this property, even though aspartame produces 4 ... Aspartame is rapidly hydrolyzed in the small intestines. Even with ingestion of very high doses of aspartame (over 200 mg/kg), ... The PBOI concluded aspartame does not cause brain damage, but it recommended against approving aspartame at that time, citing ...
Learn more about the side effects of aspartame, and the alternatives, here. ... The food additive aspartame is a sweetener used in many foods and drinks. It is controversial and has a range of purported side ... The EFSA ruled aspartame safe for human consumption and set an acceptable daily intake or ADI of aspartame at 40 milligrams (mg ... Alternatives to aspartame. Those wishing to limit their intake of aspartame can try an alternative natural sweetener from the ...
PepsiCo said it would reintroduce the aspartame-sweetened version of Diet Pepsi in U.S. stores in September, its latest attempt ... Aspartame has been the soda industrys go-to diet sweetener since the 1980s-and the longstanding focus of consumer health fears ... PepsiCo to Reintroduce Aspartame-Sweetened Diet Pepsi The company says it will continue to sell sucralose-sweetened Diet Pepsi ... One Diet Pepsi TV spot featured an ice-filled glass being filled with aspartame-free Diet Pepsi as Doris Troys "Just One Look ...
aspartame synonyms, aspartame pronunciation, aspartame translation, English dictionary definition of aspartame. n. An ... aspartame. Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.. Related to aspartame: Acesulfame potassium ... Effects of aspartame on fetal kidney: a morphometric and stereological study/Efectos del aspartame en el rinon fetal: estudios ... Aspartame - definition of aspartame by The Free Dictionary https://www.thefreedictionary.com/aspartame ...
This article reviews the similarities and differences between sucralose and aspartame. ... aspartame. Sucralose and aspartame are sugar replacements that are used to sweeten foods or beverages without adding a ... Similarly, aspartame-based sweeteners contain some of the same fillers. Thus, while aspartame- and sucralose-based sweeteners ... Aspartame. Aspartame comprises two amino acids - aspartic acid and phenylalanine. While these are both naturally occurring ...
A study found drinking aspartame-sweetened diet soda daily increases the risk of type 2 diabetes by 67 percent and the risk of ... A study found drinking aspartame-sweetened diet soda daily increases the risk of type 2 diabetes by 67 percent and the risk of ... Aspartame May Promote Obesity by Blocking Gut Enzyme Activity. A study on mice revealed that animals fed aspartame-laced ... The Aspartame End Game... And Whats Next. *Aspartame Update: Coke Illegally Claims Diet Soda Can Combat Obesity, and ...
... Dr. Betty Martini, D. Hum. Photos Copyright Stephanie Relfe 2010. Relfe.com. 3-8-13 ... She asked, "Why would they spray aspartame on crops". I said, "Its a systemic neurotoxin; it will kill the bugs just like it ... I told Monsanto years ago they could make just as much money selling aspartame as a rat poison, just change the label. It ...
Aspartame/NutraSweet: The History of the Aspartame Controversy By James Turner, ESQ. Director of the National Institute of ... of aspartame. She says in her report that in order to be certain that aspartame is safe, further clinical tests are needed. ... How Aspartame Became Legal - The Timeline. From Rich Murray [email protected] 12-24-2. From Norfolk Genetic Information Network ... further testing because aspartame is very unstable in liquid form. When liquid aspartame is stored in temperatures above 85 ...
... chances are you have eaten or drank products containing aspartame. ... Symptoms which May be Due to Aspartame. What kinds of symptoms may occur as a result of ingesting aspartame? They may involve ... If they do, you should probably eliminate aspartame entirely. Mechanisms in the Biochemistry and Pharmacology of Aspartame ... How much aspartame do Americans eat? The average American consumes over 14 pounds of aspartame each year and this amount has ...
The Role Of Aspartame, MSG And Other Excitotoxins. By Russell L. Blaylock, MD. 2-28-5. Over 460,000 people per year are now ... High consumption of aspartame adds an additional cardiac muscle toxin, methanol. A number of studies have shown that consuming ... He can be seen in the movie, Sweet Misery: A Poisoned World on aspartame. You can get a copy from [email protected] ... Previously, it was thought that excitotoxin food additives, such as monosodium glutamate and aspartic acid in aspartame, cause ...
The duration of exposure to aspartame is inadequate in the study.". Ninety-two symptoms caused by aspartame were disclosed, ... The AARP questionnaire/study hailed as proof that aspartame does not cause cancer was not an aspartame study. ... markers to get aspartame approved." This, despite the overwhelming evidence aspartame caused brain and breast cancers in ... Denial that aspartame causes cancer was circulated to the public in a press release written by the Calorie Control Council, an ...
Aspartame has the chemical formula C14H18N2O5. Aspartame is the methyl ester of the dipeptide of the natural amino acids L- ... The taste of aspartame is not identical to that of sugar: the sweetness of aspartame has a slower onset and longer duration ... Aspartame is also one of the sugar substitutes used by diabetics. However, aspartame is not always suitable for baking because ... While aspartame, like other peptides, has a caloric value of 4 kilocalories (17 kilojoules) per gram, the quantity of aspartame ...
The safety of aspartame and its metabolic constituents was established through extensive toxicology studies in laboratory ... Over 20 years have elapsed since aspartame was approved by regulatory agencies as a sweetener and flavor enhancer. ... Aspartame: review of safety Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 2):S1-93. doi: 10.1006/rtph.2002.1542. ... The safety testing of aspartame has gone well beyond that required to evaluate the safety of a food additive. When all the ...
In France, aspartame has been permitted since 1988. The Acceptable Daily Intake (ADI) of aspartame for humans was fixed at 40 ... Aspartame Assessment Report chap. 3: Identity, physical and chemical properties and stability of aspartame. ... Aspartame has also been considered by other bodies including the Joint FAO/WHO Expert Committee on Food Additives (JECFA, 1980 ... The safety of aspartame and its metabolic breakdown products (phenylalanine, aspartic acid and methanol) has been assessed in ...
... has written an excellent article about aspartame: Aspartame - Truth vs Fiction. The article is on the Science-Based Medicine ... I will comment however on one aspect of the aspartame controversy. ... has written an excellent article about aspartame: Aspartame - Truth vs Fiction. The a... ... Steven Novella MD, has written an excellent article about aspartame: Aspartame - Truth vs Fiction. The article is on the ...
Aspartame, Ketogenic Diets and Health. Both aspartame and ketogenic diets have been known to pose health risks. In an August 4 ... Aspartame and Ketosis. Aspartame is a calorie-free artificial sweetener found in diet soft drinks and other sugar-free products ... Before you add another spoonful of aspartame to your coffee or chug another diet soda, however, consider aspartames impact on ... Joseph Mercola blasts aspartame as a deadly neurotoxin, citing episodes from its hard-won battle for U.S. Food and Drug ...
FDA Statement on Aspartame, November 18, 1996 "Aspartame - what it is and why its used in our food". Food Standards Australia ... The controversy over aspartame safety originated in perceived irregularities in the aspartame approval process during the 1970s ... "EFSA makes aspartame studies available". Food Navigator. 2011. Retrieved November 25, 2011. "EFSA delay Aspartame review ... In December 1975, the FDA placed a stay on the aspartame approval, preventing Searle from marketing aspartame. The Searle ...
  • Aspartame ( APM ) is an artificial non- saccharide sweetener used as a sugar substitute in some foods and beverages. (wikipedia.org)
  • This makes aspartame undesirable as a baking sweetener, and prone to degradation in products hosting a high pH, as required for a long shelf life. (wikipedia.org)
  • In products that may require a longer shelf life, such as syrups for fountain beverages , aspartame is sometimes blended with a more stable sweetener, such as saccharin . (wikipedia.org)
  • Aspartame: An artificial sweetener used in place of sugar because it has few calories. (webmd.com)
  • Aspartame is an artificial sweetener, sold under brand names such as NutraSweet® and Equal®, that has been in use in the United States since the early 1980s. (cancer.org)
  • Aspartame is commonly used as a tabletop sweetener, as a sweetener in prepared foods and beverages, and in recipes that don't require too much heating (since heat breaks down aspartame). (cancer.org)
  • The US Food and Drug Administration (FDA) has concluded that "the use of aspartame as a general purpose sweetener… is safe. (cancer.org)
  • About a year ago, I covered aspartame, the sometimes-maligned intense artificial sweetener. (scienceblogs.com)
  • Aspartame is metabolized via esterases and peptidases - esterases remove the methyl ester as methanol (tiny, tiny quantities, but this is a big part of why some people insist this is a dangerous sweetener). (scienceblogs.com)
  • Aspartame is being replaced with Sucralose, a sweetener made from sugar. (scienceblogs.com)
  • Aspartame is an artificial sweetener, often denoted as E951. (healthline.com)
  • Aspartame is an artificial sweetener, originally marketed as NutraSweet. (healthline.com)
  • As a low-calorie sweetener, aspartame is commonly consumed by people who want to enjoy the sweetness but need to limit their sugar intake. (healthline.com)
  • Aspartame is a commonly used artificial sweetener found in many food items. (bellaonline.com)
  • Aspartame is an intense sweetener, approximately 200 times sweeter than sugar, which has been used in soft drinks and other low-calorie or sugar-free foods throughout the world for more than 25 years. (nationalarchives.gov.uk)
  • In the case of aspartame, an adult would have to consume 14 cans of a sugar-free drink every day before reaching the ADI, assuming the sweetener was used in the drink at the maximum permitted level. (nationalarchives.gov.uk)
  • Aspartame is a low-calorie sweetener used in many foods and drinks. (scitoys.com)
  • The artificial sweetener aspartame has been the subject of several controversies since its initial approval by the U.S. Food and Drug Administration (FDA) in 1974. (wikipedia.org)
  • The weight of existing scientific evidence indicates that aspartame is safe as a non-nutritive sweetener. (wikipedia.org)
  • Aspartame is a low-calorie, intense artificial sweetener. (europa.eu)
  • The sweetener aspartame and its breakdown products have been a matter of extensive investigation for more than 30 years including experimental animal studies, clinical research, intake and epidemiological studies and post-marketing surveillance. (europa.eu)
  • Since 2002, EFSA has kept the safety of aspartame under regular review and its Scientific Panels have issued several opinions on studies related to this sweetener. (europa.eu)
  • Aspartame is a widely used, low-calorie, artificial sweetener and one of the most popular sugar substitutes in low-calorie food and drinks, including diet sodas. (medicalnewstoday.com)
  • Despite its extensive use and popularity, aspartame has become a source of controversy in recent years with several studies claiming the sweetener has adverse side effects. (medicalnewstoday.com)
  • Less than a year after launching its new Diet Pepsi with sucralose-and abandoning the controversial sweetener aspartame-PepsiCo has made an about-face. (wsj.com)
  • Aspartame is a low-calorie sweetener made by linking the amino acid aspartic acid to a second amino acid, phenylalanine. (thefreedictionary.com)
  • 5 June 2009 - A recently-published study by the ADA Evidence Analysis Library has come to the conclusion that using aspartame as a sweetener has no effect on appetite or food intake. (thefreedictionary.com)
  • Research by Nielsen suggests fears over the health risks of artificial sweetener aspartame have dented supermarket sales in New Zealand of low- and no-calorie drinks such as Coke Zero and produced a resurgence in their full sugar counterparts. (thefreedictionary.com)
  • A study on mice revealed that animals fed aspartame-laced drinking water gained weight and developed symptoms of metabolic syndrome while mice not fed the artificial sweetener did not. (mercola.com)
  • On January 21, 1981, the day after Ronald Reagan's inauguration, Searle re-applied to the FDA for approval to use aspartame in food sweetener, and Reagan's new FDA commissioner, Arthur Hayes Hull, Jr., appointed a 5-person Scientific Commission to review the board of inquiry's decision. (rense.com)
  • Questions are also raised about safety of saccharin, the only other artificial sweetener on the market, leaving the field wide open for aspartame. (rense.com)
  • December 18, 1970-- Searle Company executives lay out a 'Food and Drug Sweetener Strategy' that they feel will put the FDA into a positive frame of mind about aspartame. (rense.com)
  • In April, 1993, aspartame was approved for use in baked goods and mixes which greatly added to the 4,200 products already containing the synthetic sweetener. (healthy.net)
  • While cardiologists have found coronary disease and suspect previous scars from silent heart attacks in a number of these individuals, one mechanism is getting no attention at all, and that is excitotoxic damage caused by food additives and the artificial sweetener aspartame. (rense.com)
  • Media blitz by the artificial sweetener industry denies aspartame (Equal, NutraSweet) link to cancer. (prweb.com)
  • Since I am a reluctant expert on the subject of the chemical sweetener, aspartame, I think I would have noted questions pertaining to chemical sweeteners. (prweb.com)
  • Marilyn Marchione of the Associated Press writes the AARP study "takes the fizz out of arguments that the diet soda sweetener aspartame might raise the risk of cancer. (prweb.com)
  • Aspartame further synergizes with other sweeteners, allowing use of less total sweetener, and it also intensifies and extends fruit flavors (Blachford 2002). (newworldencyclopedia.org)
  • Aspartame is an attractive sweetener because it is approximately 200 times sweeter than sugar (sucrose) in typical concentrations, without the high energy value of sugar. (newworldencyclopedia.org)
  • While aspartame, like other peptides , has a caloric value of 4 kilocalories (17 kilojoules) per gram, the quantity of aspartame needed to produce a sweet taste is so small that its caloric contribution is negligible, which makes it a popular sweetener for those trying to avoid calories from sugar. (newworldencyclopedia.org)
  • Blends of aspartame with acesulfame potassium are purported to have a more sugar-like taste, and to be more potent than either sweetener used alone. (newworldencyclopedia.org)
  • Over 20 years have elapsed since aspartame was approved by regulatory agencies as a sweetener and flavor enhancer. (nih.gov)
  • Following a recap of the physical and chemical properties of aspartame, this report will review, firstly, the available toxicological and epidemiological data on the effects of this additive on the nervous system ( cancer and seizures) and secondly, the estimates of the consumption of this sweetener by the general population and by specific populations such as children and diabetic adolescents. (greenfacts.org)
  • Aspartame is an artificial sweetener that was synthesized in 1965 and approved by the FDA in 1974. (opposingviews.com)
  • Aspartame is a calorie-free artificial sweetener found in diet soft drinks and other sugar-free products. (livestrong.com)
  • In response to research published by Italian scientists that suggests that the artificial sweetener aspartame can cause cancer , the U.S. consumer organization Center for Science in the Public Interest requested an urgent Food and Drug Administration (FDA) review of the product's safety in June 2007. (medicinenet.com)
  • Scientists from ERF concluded from their study that aspartame causes cancer and that current uses and consumption of the sweetener should be reevaluated. (medicinenet.com)
  • The U.S. FDA approved aspartame as a synthetic sweetener in 1981. (mercola.com)
  • Aspartame is an artificial sweetener made up of two amino acids , phenylalanine and aspartic acid, and an alcohol, methanol. (howstuffworks.com)
  • Aspartame, no matter how ridiculous it sounds, is an artificial sweetener that is added to foods and drinks to acquire distinct level of sweetness. (thegreenguide.com)
  • A. Aspartame (NutraSweet, Equal) is a popular artificial sweetener and an ingredient often found in diet sodas and other food products. (chicagotribune.com)
  • Aspartame is a noncaloric synthetic sweetener found in many soft drinks, and it is formed by combining the amino acids phenylalanine and aspartic acid. (reference.com)
  • Aspartame was finally approved as a general sweetener in the United States in 1996. (reference.com)
  • Aspartame was mentioned once when it asked what sweetener they put in tea and coffee. (rense.com)
  • A Florida doctor claims to have discovered a link between benign intracranial hypertension and aspartame disease - chronic methanol poisoning caused by the use of products containing this chemical sweetener. (healthy.net)
  • All were also preoccupied with their weight and consumed considerable amounts of the artificial sweetener aspartame, mainly as diet drinks. (healthy.net)
  • The European Food Safety Authority (EFSA) has received the primary data for Ramazzini Foudation's recent study on the sweetener aspartame and is commencing its risk assessment as a matter of priority. (foodnavigator.com)
  • Up until now the regulator has not been urging consumers to avoid aspartame, which is used in more than 6,000 food and drink products in the EU and as a table-top sweetener. (foodnavigator.com)
  • the sweetness you taste may be due to the artificial sweetener aspartame. (livestrong.com)
  • Aspartame is also used as a powdered sweetener by diabetics and other individuals trying to cut down on calories and sugar. (livestrong.com)
  • Only consume aspartame within the acceptable amounts, and read food labels to check which of the foods you are eating contain this artificial sweetener, since it is added to a surprising number of foods and beverages, even chewing gum. (livestrong.com)
  • To start off, Rumsfeld is responsible for contributing to the approval of the artificial sweetener Aspartame. (infowars.com)
  • A new review has revealed that there is no proof that Aspartame, a non- nutritive sweetener, has adverse effects on health or that it causes cancer, neurological damage or other problems in humans. (medindia.net)
  • In 1965, a researcher at G.D. Searle pharmaceutical company inadvertently discovered the artificial sweetener aspartame while working on an anti-ulcer medication. (redicecreations.com)
  • America's Deadliest Sweetener Betrays Millions, Then Hoodwinks You With Name Change Aspartame is the most controversial food additive in history, and its approval for use in food was the most contested in FDA history. (pearltrees.com)
  • The Aspartame Trap: You May Be Unknowingly Ingesting this Toxic Sweetener. (pearltrees.com)
  • The board of inquiry was overruled, and in 1981, aspartame was licensed by the FDA for use as a tabletop sweetener. (life-enthusiast.com)
  • Sold under the leading brands Equal and NutraSweet, aspartame is armed not just with its marketing charms, but also with the slick maneuverings of the multi-billion artificial sweetener industry and government agencies that often fail to walk their talk of consumer safety. (mercola.com)
  • What would readers think about aspartame, the artificial sweetener that's an ingredient in thousands of products, if you were privy to information regarding its harmful health effects, plus lawsuits, that have been settled out of court with documents sealed under gag order? (activistpost.com)
  • Because they're both present in the modern diet, especially in the U.S. Aspartate is a component of aspartame -- the artificial sweetener known as Equal, NutraSweet and AminoSweet. (medhelp.org)
  • When Pepsi announced last week it was dumping the artificial sweetener aspartame from its Diet Pepsi formula, it surprised many people that the soda giant would tamper with the recipe for such a successful product. (newsmax.com)
  • Pepsi will replace aspartame with sucralose - known as Splenda - a somewhat less controversial artificial sweetener, and Ace K, acesulfame potassium, a non-calorie sweetener that's 200 times sweeter than sugar. (newsmax.com)
  • Add to that various studies in rats suggesting aspartame could cause cancers like leukemia and lymphoma, and you may understand why concern about this artificial sweetener lingers. (cnn.com)
  • This was originally published as a "SkepDoc" column in Skeptic magazine under the title "Aspartame: Safe Sweetener or Perilous Poison? (sciencebasedmedicine.org)
  • Aspartame, a widespread sweetener used in many food products, is considered as a highly hazardous compound. (nih.gov)
  • Known as NutraSweet or Equal, Aspartame, is an artificial sweetener, and is 180 times as sweet as sugar. (greenmedinfo.com)
  • You've heard a lot about aspartame by now, the synthetic sweetener found in many diet soft drinks, thousands of foods and supplements. (greenmedinfo.com)
  • Hopefully you missed it, but Italy's Ramazzini Foundation recently publicized yet another study purporting to raise concerns about the safety of the intense sweetener aspartame . (foodprocessing.com)
  • From the folks that brought us Aspartame, meet Neotame, a deadly sweetener that you'll never see on a label because…well that's just the way the FDA wants it. (infowars.com)
  • Neotame is officially marketed as an inexpensive artificial sweetener made by NutraSweet, which is a former division of Monsanto and original manufacturer of aspartame . (infowars.com)
  • I] have considerable concern for the increased dissemination and consumption of the sweetener aspartame - 1-methyl N-L-a-aspartyl-L-phenylalanine - in our world food supply. (preventdisease.com)
  • I will explain why Aspartame is so dangerous: When the temperature of this sweetener exceeds 86 degrees F, the wood alcohol in ASPARTAME converts to formaldehyde and then to formic acid, which in turn causes metabolic acidosis. (grinnell.edu)
  • In response to customer feedback, PepsiCo announced on April 21 that diet pepsi with artificial sweetener aspartame will be replaced with sucralose. (medindia.net)
  • The blend replaces aspartame, an artificial sweetener approved by the US Food and Drug Administration but which has been plagued by criticism for years that it poses health risks. (medindia.net)
  • Aspartame-acesulfame salt and sucralose were both evaluated by the Scientific Committee on Food (SCF) - now the European Food Safety Authority (EFSA) - in 2000 and authorised for use as a sweetener in the Sweeteners Directive 94/35/EC as amended by Directive 2003/115/EC. (scribd.com)
  • He told me to do an aspartame challenge, so I had to buy the sweetener, pop it into a glass of water, drink it and see what happened. (healingwell.com)
  • One type of low-calorie sweetener, aspartame, has been used in foods and beverages for decades as a way to lower intake of added sugars, while still providing satisfaction from enjoying something sweet. (foodinsight.org)
  • This is why a packet of a aspartame sweetener seems equal in quantity to a packet of table sugar, for example. (foodinsight.org)
  • Regretfully, neither Governor General Jean nor Prime Minister Stephen Harper have taken seriously the need to protect Canadians from USA exports of Aspartame in Diet soda, sugarless gum, low fat yogurt, children's medications, etc., despite the fact that both have had for at least 8 months a DVD on the medical harm done by this artificial sweetener. (sott.net)
  • Mr. Taylor blames his problems on aspartame, the decade-old artificial sweetener that Monsanto Co. markets under the brand names NutraSweet and Equal. (baltimoresun.com)
  • Nine months later, discounting the board's recommendation, then-FDA Commissioner Arthur Hull Hayes Jr. approved the use of aspartame in dry foods and as a granulated table-top sweetener. (baltimoresun.com)
  • It happened to be "sweet", and with some good marketing and by switching the FDA paperwork from "drug" to "food additive", aspartame came onto the American food supply as a "sweetener. (janethull.com)
  • Is the writing finally on the wall for aspartame, the artificial sweetener used in diet and sugar-free drinks and foods? (healthy.net)
  • Two years after aspartame was introduced onto the market I first became aware of the negative impact of this artificial sweetener on the central nervous system. (sirianrevelations.net)
  • In lieu of withdrawing its aspartame approval, the agency prevailed on Searle to refrain from marketing the sweetener until after completion of the hearing process. (stevia.net)
  • By Rosanne Rust MS, RDN, LDN - Aspartame is a non-nutritive sweetener made of two amino acids (phenylalanine and aspartic acid) and methanol. (aspartame.org)
  • Neva Cochran, MS, RDN, LD April 30, 2018 - Aspartame has been approved for use as a sweetener in foods and beverages in the U.S. for over three decades. (aspartame.org)
  • Aspartame is a low-calorie sweetener that has been safely used in a variety of foods and beverages for over 30 years. (aspartame.org)
  • It proves to all consumers that the aspartame safety issue has been grossly manipulated since the 1960s, when aspartame was first labeled a sweetener instead of the ulcer drug that it was discovered to be. (janethull.com)
  • This article is the most inaccurate and biased article that I have ever read written in favor of the aspartame and artificial sweetener industry. (janethull.com)
  • : 2 The safety of aspartame has been the subject of several political and medical controversies, United States congressional hearings , and Internet hoaxes. (wikipedia.org)
  • The safety of aspartame has been studied since its discovery and it is one of the most rigorously tested food ingredients. (wikipedia.org)
  • Indeed, as part of its systematic re-evaluation of all food additives, EFSA has re-evaluated the safety of aspartame (see External sites box). (nationalarchives.gov.uk)
  • From 8 January to 15 February 2013, EFSA held an online public consultation on its draft scientific opinion on the safety of aspartame. (europa.eu)
  • In May 2011, EFSA was asked by the European Commission to bring forward the full re-evaluation of the safety of aspartame (E 951). (europa.eu)
  • In this article, we look at the most recent evidence on the safety of aspartame. (medicalnewstoday.com)
  • The AARP questionnaire has not been made available to the public, yet the National Cancer Institute is presenting statistics from the questionnaire claiming the safety of aspartame. (prweb.com)
  • The safety of aspartame and its metabolic constituents was established through extensive toxicology studies in laboratory animals, using much greater doses than people could possibly consume. (nih.gov)
  • The safety of aspartame has been assessed and recognised by a number of other national and international organisations including the FAO / WHO Committee of Experts on Food Additives ( JECFA ) and, at EU level, by the Scientific Committee on Food. (greenfacts.org)
  • Before its FDA approval, the safety of aspartame was tested in over 100 scientific studies. (medicinenet.com)
  • At that time, an EFSA press release stated that EFSA's review of ERF's study concluded, among other things, that on the basis of all evidence currently available to EFSA, ERF's conclusion that aspartame is a carcinogen is not supported by the data and the EFSA sees no need to further review its earlier scientific opinion on the safety of aspartame or to revise the Acceptable Daily Intake . (medicinenet.com)
  • Since it was first approved for use in the United States, the safety of aspartame has been questioned by some. (medicinenet.com)
  • To date, however, the agency has not been presented with scientific information that would support a change in our conclusions about the safety of aspartame. (medicinenet.com)
  • In summary, the FDA currently supports its previous position regarding the safety of aspartame. (medicinenet.com)
  • "Based on current evidence on the safety of aspartame, EFSA does not recommend that consumers who wish to choose foods containing aspartame make any changes to their dietary habits," ​ it said in an earlier statement. (foodnavigator.com)
  • Since then there has been ongoing debate amongst scientists and the media about the safety of aspartame itself and its components, aspartic acid, phenylalanine and methanol, although so far the fears have not been borne out by the available evidence. (foodnavigator.com)
  • Though there has been extensive research on the safety of aspartame, there is much debate on possible side effects, including muscle cramps and pain. (livestrong.com)
  • The safety of Aspartame for people of all ages, and with a variety of health conditions, was evaluated by an international expert panel from 10 universities and medical schools. (medindia.net)
  • There have been continued questions in the media and on the internet about the safety of aspartame. (medindia.net)
  • Truth is - and an ugly one at that - there are scientifically backed evidences and lab results showing the dangers and unproven safety of aspartame use. (mercola.com)
  • The European Food Safety Authority (EFSA) also reviewed the previous Ramazzini study of aspartame and likewise concluded that it contained no information that called into question the safety of aspartame. (foodprocessing.com)
  • The safety of aspartame is even supported by a human epidemiology study published in 2006. (foodprocessing.com)
  • Council spokesperson and toxicologist Bernadene Magnuson, PhD provides her opinion of the review "Revisiting the safety of aspartame" below. (aspartame.org)
  • More than 200 scientific studies support the safety of aspartame. (aspartame.org)
  • The American Cancer Society's opinion on the safety of aspartame is that it does not cause cancer and is not linked to health problems. (lovetoknow.com)
  • Originally sold under the brand name NutraSweet, aspartame was approved for use in food products in the 1980s. (healthline.com)
  • Aspartame is the primary component in Nutrasweet, Equal, Spoonful and Equal-Measure. (bellaonline.com)
  • Aspartic acid makes up 40% of aspartame - Nutrasweet. (bellaonline.com)
  • Aspartame is also known as Nutrasweet, Equal, Spoonful and Equal-Measure. (bellaonline.com)
  • Aspartame is available in the United States under the brand names Nutrasweet and Equal. (medicalnewstoday.com)
  • Q Is it true that aspartame (Nutrasweet) causes cancer? (thefreedictionary.com)
  • I finally discovered, however, that ingesting aspartame (NutraSweet) would trigger an ocular migraine within a few hours. (thefreedictionary.com)
  • Sucralose is widely sold under the brand name Splenda, while aspartame is typically found as NutraSweet or Equal. (healthline.com)
  • In 1985 Monsanto purchased G.D. Searle, the chemical company that held the patent to aspartame, the active ingredient in NutraSweet. (rense.com)
  • Aspartame is known commercially as "Nutrasweet" when added to products or "Equal" when it is in the form of a sugar substitute in a packet. (healthy.net)
  • The media blitz is on to discredit Dr. Morando Soffritti and the Ramazzini Cancer institute's 7-year study showing aspartame (Equal, NutraSweet) causes cancer, especially lymphoma and leukemia. (prweb.com)
  • Aspartame is 180 to 200 times sweeter than sugar (Herbst 2001) and is marketed under a number of trademark names, such as NutraSweet ® , Equal, and Canderel. (newworldencyclopedia.org)
  • Aspartame is the technical name for the brand names NutraSweet, Equal, Spoonful, and Equal-Measure. (mercola.com)
  • NutraSweet, which was manufactured in 1965, was the very first brand of aspartame sold to the market. (thegreenguide.com)
  • Methanol, also known as methyl alcohol, is a prime component of aspartame and nutrasweet. (bellaonline.com)
  • Sold under the names Equal and NutraSweet, aspartame is a dipeptide methyl ester of L-aspartyl-L-phenylalanine that is approximately 200 times sweeter than sugar. (reference.com)
  • Aspartame is marketed under the brand names NutraSweet, Canderel and E951 in Europe. (livestrong.com)
  • Nutrasweet is the brand name of aspartame. (reference.com)
  • I've also heard that when artificial sweeteners like aspartame and nutrasweet get too hot, they actually turn toxic. (healthboards.com)
  • Because there are a few scientific inaccuracies in the email, Monsanto/NutraSweet may attempt to create the image that aspartame poisoning is a hoax and that the email is a hoax. (holisticmed.com)
  • Please see the case histories, scientific FAQs, and other important details on the Aspartame / NutraSweet Toxicity Information Center web page for more details. (holisticmed.com)
  • Probably nothing encapsulates the aspartame 'pedigree' more than the article "The Aspartame / NutraSweet Fiasco" written by Attorney James S. Turner, with whom I've been in contact since the 1980s. (activistpost.com)
  • Later Searle lawyer Robert Shapiro named aspartame NutraSweet. (activistpost.com)
  • Aspartame is a low calorie sugar substitute marketed under brand names like Equal and Nutrasweet. (sciencebasedmedicine.org)
  • However the FDA still refused to allow Nutrasweet (aspartame) on the market. (preventdisease.com)
  • I have spent several days lecturing at the WORLD ENVIRONMENTAL CONFERENCE on 'ASPARTAME,' marketed as 'NutraSweet,' 'Equal,' and 'Spoonful. (grinnell.edu)
  • There are more than 4,000 aspartame-sweetened products, NutraSweet reminds Americans with the $25 million advertising campaign it launched last month in honor of its 10th anniversary. (baltimoresun.com)
  • In 1980, a scientific board selected by the FDA, NutraSweet and concerned consumer groups recommended that aspartame should not be approved without more research. (baltimoresun.com)
  • Thank you for the information relating to aspartame & Nutrasweet. (earthrainbownetwork.com)
  • Searle was bought by Monsanto in 1985 , which formed the Nutrasweet Company to market aspartame. (coactivate.org)
  • Many health-conscious people believe that avoiding aspartame, found in over 5000 products under brand names such as Equal and NutraSweet, can improve their quality of life. (stevia.net)
  • Since it was first introduced to the consumer market four decades ago, aspartame, the main ingredient in low-calorie sweeteners like Equal and Nutrasweet, has sparked controversy in the medical and scientific world. (lovetoknow.com)
  • Aspartame is a methyl ester of the aspartic acid / phenylalanine dipeptide . (wikipedia.org)
  • Beta-aspartame differs from aspartame based upon which carboxyl group of aspartate binds to the nitrogen of phenylalanine. (wikipedia.org)
  • In 2013, a study published in Folia Neuropathology found that aspartame is metabolized into three toxic molecules - phenylalanine, aspartic acid and methanol. (sourcewatch.org)
  • Aspartame is manufactured from phenylalanine produced by a genetically modified (GM) strain of E. coli, a bacterium normally found in the bowel. (sourcewatch.org)
  • Because aspartame contains a small amount of phenylalanine, foods containing aspartame sold in the United States must state: "Phenylketonurics: Contains Phenylalanine" on product labels. (wikipedia.org)
  • In Canada, foods that contain aspartame are required to list aspartame among the ingredients, include the amount of aspartame per serving, and state that the product contains phenylalanine. (wikipedia.org)
  • Concerns about the safety of phenylalanine from aspartame for those without phenylketonuria center largely on hypothetical changes in neurotransmitter levels as well as ratios of neurotransmitters to each other in the blood and brain that could lead to neurological symptoms. (wikipedia.org)
  • Aspartame is actually a dipeptide, a small protein made of two amino acids, phenylalanine and aspartic acid. (healthline.com)
  • Aspartame is a minor source of phenylalanine compared to the amounts you get from other foods, so this is not a cause for concern. (healthline.com)
  • Aspartame is a source of phenylalanine, an essential amino acid. (healthline.com)
  • Since aspartame is also a source of phenylalanine, all food products containing aspartame are clearly labelled to indicate the presence of phenylalanine so that those people who suffer from PKU can avoid consuming these products. (nationalarchives.gov.uk)
  • Aspartame (L-aspartyl-L- phenylalanine methyl ester) (E 951) is a dipeptide of L-phenylalanine methyl ester and L- aspartic acid , which are two amino acids usually found in proteins . (greenfacts.org)
  • After oral ingestion , aspartame is rapidly and completely hydrolysed in the gastrointestinal tract to its degradation products, which are mostly phenylalanine, aspartic acid, and methanol . (greenfacts.org)
  • This is why it is recommended to persons suffering from phenylketonuria to not consume aspartame, which is a source of phenylalanine . (greenfacts.org)
  • Meanwhile, in calculating a safe level of aspartame exposure (based on plasma phenylalanine concentrations), the expert Panel of EFSA assumed the worst-case scenario, and concluded that aspartame consumption was not of safety concern at the current aspartame and its degradation products exposure estimates, which are below their respective Acceptable Daily Intake (ADI) recommended in 2006 (40 mg/kg bw/day for aspartame). (greenfacts.org)
  • In calculating a safe level of aspartame exposure (based on plasma phenylalanine concentrations), the Panel assumed the worst-case scenario. (greenfacts.org)
  • Therefore, there was no reason to revise the ADI of aspartame, which however is not applicable to PKU patients who should limit as much as possible their exposure to any source of phenylalanine, including in their regular diet. (greenfacts.org)
  • The Panel noted that in all the repeat aspartame administration studies, where human healthy adults, children or patients suffering various diseases, including PKU individuals, received daily dose of aspartame above the current ADI of 40 mg/kg/day for periods up to 6 months, no significant increase in plasma phenylalanine concentration was observed. (greenfacts.org)
  • Therefore, that there is no risk of phenylalanine accumulation in such human populations with normal uses levels of aspartame (at or below the ADI). (greenfacts.org)
  • Aspartame comprises two amino acids - aspartic acid and phenylalanine. (healthline.com)
  • Aspartame is the methyl ester of the dipeptide of the natural amino acids L- aspartic acid and L- phenylalanine . (newworldencyclopedia.org)
  • Several scientific issues continued to be raised after approval, largely as a concern for theoretical toxicity from its metabolic components--the amino acids, aspartate and phenylalanine, and methanol--even though dietary exposure to these components is much greater than from aspartame. (nih.gov)
  • Aspartame is a dipeptide methyl ester of L-aspartyl-L- phenylalanine . (greenfacts.org)
  • It is broken down to numerous chemicals one of which is phenylalanine, and therefore people with phenylketonuria (PKU) must avoid products containing aspartame. (opposingviews.com)
  • Aspartame, which has been on the U.S. market since 1981, is composed primarily of two common amino acids, aspartic acid and phenylalanine. (medicinenet.com)
  • However, because of its phenylalanine component, aspartame does carry a risk for people with the rare genetic disorder phenylketonuria . (medicinenet.com)
  • People who have this disorder should avoid or restrict aspartame use because of their body's difficulty in metabolizing phenylalanine. (medicinenet.com)
  • After you eat or drink an aspartame-sweetened product, aspartame breaks down into its starting components: phenylalanine, aspartate, and methanol. (howstuffworks.com)
  • The main residual components of aspartame include aspartic acid, methanol, and phenylalanine. (thegreenguide.com)
  • Phenylalanine is another substance found when aspartame is broken down. (thegreenguide.com)
  • Because it contains the essential amino acid phenylalanine, found in all proteins, aspartame may be a concern if you have a rare birth defect called phenylketonuria (PKU). (chicagotribune.com)
  • The only group for whom EFSA considered aspartame consumption to be risky was for those with phenylketonuria, characterised by an inability to break down the amino acid phenylalanine, which is present in aspartame as well as a wide variety of other foods. (foodnavigator.com)
  • Apart from phenylalanine, the opinion also clarifies that other breakdown products of aspartame, such as methanol and aspartic acid, are also naturally present in other foods. (foodnavigator.com)
  • People with PKU cannot break down phenylalanine, which is one of the byproducts of aspartame in your body. (livestrong.com)
  • Aspartame is made by combining the two amino acids aspartic acid and phenylalanine. (reference.com)
  • Aspartame is a dipeptide, but breaks down into the following chemicals: methanol (wood alchol) -- whether aspartame is heated or not, aspartic acid, phenylalanine, aspartylphenylalanine diketopiperazine (DKP), beta-aspartame, and a few odds and ends. (holisticmed.com)
  • Aspartame breaks down into methanol (wood alcohol) -- whether it is heated or not, free-form aspartic acid, aspartylphenylalanine diketopiperazine (DKP), phenylalanine, beta-aspartame, and a few other chemicals. (holisticmed.com)
  • However, many researchers believe that the adverse neurological effects of aspartame may be at least partially due to the phenylalanine derived from aspartame ingestion. (holisticmed.com)
  • Because the phenylalanine from aspartame is in free-form (unbound to protein), it is absorbed suddenly and can spike the blood plasma levels of phenylalanine (Caballero 1986, Matalon 1988, Stegink 1987). (holisticmed.com)
  • Nor does this phenylalanine "rush" occur when ingesting aspartame in capsules (Stegink 1987). (holisticmed.com)
  • Wurtman (1988) reviews the research to show that a dose of 60 times more aspartame is needed for rodent studies to simulate the change in phenylalanine/LNAA ratio change that occurs in humans. (holisticmed.com)
  • Countering claims that lab tests indicated little harm from small amounts of aspartame, Dr Elsas noted, "Normal humans do not metabolize phenylalanine as efficiently as do lower species, such as rodents, and thus most of the previous studies in aspartame effects on rats are irrelevant to eh question. (preventdisease.com)
  • This is due to the depletion of serotonin caused by the phenylalanine in aspartame. (preventdisease.com)
  • When you introduce abnormally large amounts of phenylalanine and aspartic acid (synthetically bound together by an ester bond) into your bloodstream - which is exactly what happens whenever you drink a can of soda that is sweetened with aspartame - your cells can be overwhelmed. (drbenkim.com)
  • ADHD and PKU linked through Phenylalanine and Aspartame? (hubpages.com)
  • This article looks at a possible link of ADHD with Aspartame, a disease known as PKU and the effects of chemical processes involved with phenylalanine. (hubpages.com)
  • Upon ingestion, aspartame breaks down into its components, including phenylalanine and methanol. (hubpages.com)
  • Thus the higher level of phenylalanine from the aspartame triggers the worse hyperactive state, but eventually returns to the (normal but high)level as it is slowly converted and made into dopamine. (hubpages.com)
  • Aspartame consists of the amino acids aspartic acid and phenylalanine, which are building blocks of protein, and is about 200 times sweeter than sugar. (foodinsight.org)
  • Phenylketonuria (PKU) is a rare genetic disease that makes an affected person unable to properly metabolize phenylalanine, one of the amino acids found in aspartame and many common foods. (foodinsight.org)
  • While aspartame does adversely effect some people including those who are unable to metabolize the amino acid phenylalanine it has been tested more than 200 times, and each test has confirmed that your Diet Coke is safe to drink. (time.com)
  • Also, no differences were noted for any of the biochemical measures, except for the expected increase in plasma phenylalanine and tyrosine following aspartame. (aappublications.org)
  • They found that aspartame could cause brain damage and was dangerous for people with PKU (Phenenlyketonuria), a genetic disease that causes people to be unable to break down phenylalanine. (lovetoknow.com)
  • Closely monitor everything you eat to avoid ingesting phenylalanine or products containing aspartame. (lovetoknow.com)
  • Coincidentially, the Calorie Control Council represents the companies making low-calorie foods that contain aspartame. (bellaonline.com)
  • Does Splenda contain aspartame? (healthline.com)
  • Thus, while aspartame- and sucralose-based sweeteners share some of the same fillers, Splenda does not contain aspartame. (healthline.com)
  • Splenda does not contain aspartame, though it has fillers that are also found in aspartame-based sweeteners. (healthline.com)
  • Which Diet Sodas Do Not Contain Aspartame? (livestrong.com)
  • You might be surprised by the number of products that contain aspartame. (responsibletechnology.org)
  • Some prescription and over-the-counter medications and chewable vitamins may contain aspartame to increase palatability. (foodinsight.org)
  • It's a major worry for anyone who takes vitamin supplements that they could contain aspartame. (healthy.net)
  • According to the Aspartame Information Center, more dry products contain aspartame than do drink products. (aacrjournals.org)
  • If you find a product you bought contains this poison return it to the store and insist on getting your money back or a substitute that does not contain aspartame. (aspartame.ca)
  • Centrum,Jr vitamins contain aspartame. (aspartame.ca)
  • Compared to other dietary sources, aspartame is a minor source of aspartic acid. (healthline.com)
  • Aspartame is a minor source of aspartic acid, a naturally-occurring amino acid found in foods that contain protein. (healthline.com)
  • Spring 1971-- Neuroscientist Dr. John Olney (whose pioneering work with monosodium glutamate was responsible for having it removed from baby foods) informs Searle that his studies show that aspartic acid (one of the ingredients of aspartame) caused holes in the brains of infant mice. (rense.com)
  • Previously, it was thought that excitotoxin food additives, such as monosodium glutamate and aspartic acid in aspartame, cause their damage in the cardiovascular centers in the brain stem and/or by over stimulating sympathetic centers in the hypothalamus of the brain. (rense.com)
  • Basically, prior to the breakdown, aspartame already consists of 40% aspartic acid, which is a substance known for increasing the body's alcohol level and headaches. (thegreenguide.com)
  • Aspartic acid a major component of aspartame is a non-essential amino acid. (thegreenguide.com)
  • Of the three components of aspartame - phenylaline, aspartic acid and methanol, methanol is only 10% of the makeup. (bellaonline.com)
  • Dr. John Olney, a neuropathologist and neuroscientist, pointed out to FDA investigators that aspartame contained at least two distinct components that could harm the brain-diketopiperizine and aspartic acid. (redicecreations.com)
  • Dr. Olney had already shown that aspartic acid (one aspartame component) caused microscopic holes in the brains of rats after each feeding. (stevia.net)
  • The methanol produced during the digestion of aspartame is only a small part of the total dietary intake. (healthline.com)
  • As aspartame is digested, low amounts of methanol are formed. (healthline.com)
  • Aspartame is only a minor source of methanol in the diet, so it is not considered to be a problem. (healthline.com)
  • Aspartame is made from two amino acids and methanol. (scitoys.com)
  • High consumption of aspartame adds an additional cardiac muscle toxin, methanol. (rense.com)
  • Under strongly acidic or alkaline conditions, aspartame first generates methanol by hydrolysis . (newworldencyclopedia.org)
  • Your question really deals more with the potential effects of the methanol in aspartame than with aspartame itself. (howstuffworks.com)
  • The big debate is whether there's enough of these toxins produced from the methanol in aspartame to damage your body. (howstuffworks.com)
  • Methanol is another substance found when aspartame is broken down. (thegreenguide.com)
  • Most pro-aspartame sites compare the methanol volume with that found in tomato juice. (bellaonline.com)
  • Most industry-sponsored tests of aspartame didn't even start counting until 4mg/l, so a person could in essence have a 400% increase of methanol in their system without it being noticed at all. (bellaonline.com)
  • This is because heating aspartame over 86F turns the methanol into formaldehyde. (bellaonline.com)
  • So either you ingest the methanol and your body turns it into formaldehyde, or you heat up the aspartame (in your coffee or in cooking) and it turns into formaldehyde before you even consume it. (bellaonline.com)
  • Find out for yourself if you are sensitive to methanol and aspartame. (bellaonline.com)
  • Some of the potential health problems potentially linked to aspartame in some studies include alteration of the brain's neurochemical composition, changes in neuroendocrine functions, methanol toxicity, brain tumors and epilepsy. (reference.com)
  • following aspartame ingestion, methanol or formaldehyde is distributed all over the place. (holisticmed.com)
  • Methanol levels do not rise after aspartame ingestion. (holisticmed.com)
  • A. The aspartame manufacturers funded 13 years of studies where a 1960's methanol testing procedure was used. (holisticmed.com)
  • Astrocytes do not play a significant role in methanol poisoning due to a permanent consumption of large amounts of aspartame. (nih.gov)
  • Chronic exposure to aspartame results in oxidative stress in the brain of albino rats, as well as methanol formation. (greenmedinfo.com)
  • Methanol, or wood alcohol in aspartame breaks down further in heat and in the body, into Formaldehyde (embalming fluid), Formic Acid (venom in ant stings) and the most deadly of all - Diketopiperazine (DKP), a brain tumor agent. (infowars.com)
  • When heated to 86 degrees Fahrenheit (human body ~ 98.6) -- aspartame releases free methanol that breaks down into formic acid and formaldehyde in the body. (preventdisease.com)
  • One quart of aspartame-added beverage contains about 56 mg of methanol. (preventdisease.com)
  • Physicians and legislators could recommend to the Health and Justice Ministers of Indonesia that this ban must be made permanent, because of the long list of neurodegenerative illnesses caused by Aspartame/Methanol/Formaldehyde/Diketopiperazine, all proven brain tumor causal factors. (sott.net)
  • It was once on the Pentagon list of biowarfare chemicals submitted to Congress and, in 1984, Dr Woodrow C Monte observed: 'Methanol (one of the breakdown products of aspartame) has no therapeutic properties and is considered only as a toxicant. (healthy.net)
  • The US Environmental Protection Agency advises daily maximum methanol consumption of just 7.8 mg - and yet, many cans of diet sodas contain twice that, and a diabetic using aspartame all day could consume 30 times that amount. (healthy.net)
  • The methanol in the aspartame converts to formaldehyde in the retina of the eye. (spiritual-endeavors.org)
  • This means that only a tiny amount of aspartame is necessary to sweeten foods and drinks. (medicalnewstoday.com)
  • Being 200 times sweeter than sugar, only a small amount of aspartame is used in commercial sweeteners. (healthline.com)
  • Mice in the study were fed either plain water or water infused with the equivalent amount of aspartame found in two to 3 1/2 cans of soda, along with a normal diet or a high-fat diet. (mercola.com)
  • For the same level of sweetness as sugar, a less amount of aspartame (and less calories) is required. (newworldencyclopedia.org)
  • Nevertheless, reviews and tests reveal that the needed amount of aspartame to reach its desired sweetness is so minute its possible negative effects to the body are negligible. (thegreenguide.com)
  • Table 1 , from the European Ramazzini Foundation, estimates the average daily amount of aspartame consumed from some of the most commonly used products out of the more than 6,000 in which it is present ( 3 ). (aacrjournals.org)
  • No credible evidence was found that aspartame is carcinogenic, neurotoxic, or has any other adverse effect on health when consumed even at quantities many times the established ADI (Acceptable Daily Intake) levels. (preparedfoods.com)
  • It follows a 5.2 percent drop in sales of Diet Pepsi in 2014, and a survey found that aspartame is the main reason many consumers avoid diet sodas. (newsmax.com)
  • One study found that aspartame became a brain toxin when combined with a common food coloring. (newsmax.com)
  • Though research into a possible link between aspartame and cancer continues, these agencies agree that studies done so far have not found such a link. (cancer.org)
  • Further research on human participants might lead to a better understanding of the link between aspartame consumption and appetite control. (medicalnewstoday.com)
  • It is this formation of formaldehyde that is the link between aspartame and lymphoma and leukemia. (mercola.com)
  • The review, "Aspartame: A Safety Evaluation Based on Current Use Levels, Regulations, and Toxicological and Epidemiological Studies," published in the September issue of Informa Healthcare's Critical Reviews in Toxicology (Volume 37, Issue 8, pp. 629-727), also identified serious flaws in two recent European studies that claimed to find a link between aspartame and cancer in rats. (preparedfoods.com)
  • The panel also considered recent highly publicized studies by the Italian Ramazzini group that purported to show a link between aspartame and cancer in rats. (preparedfoods.com)
  • As far back as 1996, folks were writing about the potential link between aspartame and increasing brain tumor rates. (pearltrees.com)
  • An unsettling link between aspartame and genetically modified foods. (100777.com)
  • A more definitive link between aspartame and Multiple Sclerosis. (100777.com)
  • Aspartame was first made in 1965 and approved for use in food products by the U.S. Food and Drug Administration (FDA) in 1981. (wikipedia.org)
  • The FDA approval of aspartame was highly contested, beginning with suspicions of its involvement in brain cancer, alleging that the quality of the initial research supporting its safety was inadequate and flawed, and that conflicts of interest marred the 1981 approval of aspartame, previously evaluated by two FDA panels that concluded to keep the approval on hold before further investigation. (wikipedia.org)
  • The U.S. Food and Drug Administration (FDA) approved aspartame for use in food and drink back in 1981. (medicalnewstoday.com)
  • Although aspartame has been around since 1965, the Food and Drug Administration (FDA) did not approve it for use until 1981. (healthline.com)
  • The review panel spent 11 months looking at past research on aspartame, which entered the food supply in 1981 and is used in more than 6,000 food products worldwide, including most diet soft drinks and many sugar-free chewing gums. (preparedfoods.com)
  • The 1974 approval was withdrawn and after the results of these investigations were reviewed privately, aspartame was given approval once again in 1981. (redicecreations.com)
  • In 1981, Arthur Hull Hayes was appointed commissioner of the FDA and in 1983 he approved aspartame for use in beverages. (redicecreations.com)
  • Read about how Donald Rumsfeld, the same powerful political figure in the Bush administration, proved instrumental in the FDA approval of aspartame in 1981 and the political appointments leading to it. (mercola.com)
  • In January 1981 Rumsfeld told a sales meeting, according to one attendee, that he would call in his chips and get aspartame approved by the end of the year. (activistpost.com)
  • Pushed globally as a beneficial to dieters since its approval in 1981, accumulating research indicates that aspartame may actually damage the brain and cause cancer, to name but a few of a wide range of adverse health effects consumers risk by using this 'no-calorie' sugar alternative. (greenmedinfo.com)
  • Searle salesperson Patty Wood-Allott claimed that in 1981 Rumsfeld told company employees 'he would call in all his markers and that no matter what, he would see to it that aspartame be approved this year. (preventdisease.com)
  • Aspartame was forced through the United States Food and Drug Administration in 1981 by G.D. Searle, the pharmaceutical corporation that owned the patent. (sott.net)
  • Aspartame, approved by the FDA in 1981, came under fire almost immediately. (baltimoresun.com)
  • Aspartame was not approved by the Food and Drug Administration as a food additive until July 1981. (aacrjournals.org)
  • In 1981, the synthetic compound aspartame was approved for use, and it capitalized on saccharin's bad publicity by becoming the leading additive in diet colas. (time.com)
  • 2. Aspartame was approved by the FDA in 1981 . (coactivate.org)
  • After Hayes approved Aspartame in 1981, he left the FDA in 1983 to become senior scientific consultant to PR firm Burson-Marsteller , who did work for Searle. (coactivate.org)
  • Aspartame was de-regulated in 1980 by the board, but in 1981, the FDA Commissioner overruled the board and re-approved the substance for use. (lovetoknow.com)
  • Since 1981, almost every governmental regulatory body, along with many other scientific and medical journals , have deemed aspartame to be safe. (lovetoknow.com)
  • However, aspartame is not always suitable for baking because it often breaks down when heated and loses much of its sweetness, and at temperatures above 90 o F a component of it can convert to formaldehyde (Chamberlin and Narins 2005). (newworldencyclopedia.org)
  • Dr. Morando Soffritti, who led both projects, noted that so much formaldehyde developed in aspartame-exposed rats that their skin turned yellow. (mercola.com)
  • They even dismissed the second study, performed by the same team in 2007, which showed that the aspartame-exposed rats developed so much formaldehyde in their bodies that their skin turned yellow. (mercola.com)
  • It is well known aspartame turns into wood alcohol when it is consumed, however, few people realize this wood alcohol morphs into formaldehyde - the same stuff used for embalming - in the cells of your body. (mercola.com)
  • Lately, scientists discovered that further breakdown of aspartame can change it into formaldehyde and formic acid, another set of chemical ingredients that are known as culprits to a number of health woes. (thegreenguide.com)
  • formaldehyde formation from aspartame ingestion is very common and does indeed accumulate within the cell, reacting with cellular proteins (mostly enzymes) and DNA (both mitochondrial and nuclear). (bellaonline.com)
  • It is concluded that aspartame consumption may constitute a hazard because of its contribution to the formation of formaldehyde adducts. (holisticmed.com)
  • Significant toxicity of aspartame metabolites (e.g., formaldehyde) seen in numerous scientific studies. (holisticmed.com)
  • formaldehyde and excitotoxins derived from aspartame metabolism. (holisticmed.com)
  • Aspartame converts to formaldehyde and formic acid, which are highly toxic to the body, but the nervous system in particular. (greenmedinfo.com)
  • Since wood alcohol that comes with aspartame doesn't have fiber to keep it out of your bloodstream, just about all of it gets absorbed into your blood, where it can spontaneously convert to formaldehyde, a poisonous substance that is an established carcinogen. (drbenkim.com)
  • When the temperature of Aspartame exceeds 86 degrees F, the wood alcohol in AS PA RTAME coverts to formaldehyde and then to formic acid, which in turn causes metabolic acidosis. (spiritual-endeavors.org)
  • That the wood alcohol in aspartame converts to formaldehyde and then formic acid,( ant sting poison) and causes metabolic acidosis. (oocities.org)
  • [12] The taste of aspartame and other artificial sweeteners differs from that of table sugar in the times of onset and how long the sweetness lasts, though aspartame comes closest to sugar's taste profile among approved artificial sweeteners. (wikipedia.org)
  • [13] The sweetness of aspartame lasts longer than that of sucrose, so it is often blended with other artificial sweeteners such as acesulfame potassium to produce an overall taste more like that of sugar. (wikipedia.org)
  • In the United States, artificial sweeteners such as aspartame are regulated by the FDA. (cancer.org)
  • Aspartame is one of the most controversial sweeteners in the world. (healthline.com)
  • In practice most drinks use aspartame in combination with other sweeteners so that the level is considerably lower. (nationalarchives.gov.uk)
  • By contrast, a 2017 review of the latest research found no evidence that the low-calorie sweeteners aspartame, sucralose, and stevioside, were effective for weight management. (medicalnewstoday.com)
  • One way aspartame and other nonnutritive sweeteners may affect body weight is by increasing people's appetite, which may lead to a higher food consumption. (medicalnewstoday.com)
  • Yet, you may wonder how popular artificial sweeteners like sucralose and aspartame differ - and whether they're safe to use. (healthline.com)
  • Like sucralose, aspartame-based sweeteners usually contain fillers that mellow the intense sweetness ( 9 ). (healthline.com)
  • Similarly, aspartame-based sweeteners contain some of the same fillers. (healthline.com)
  • Sucralose and aspartame are artificial sweeteners. (healthline.com)
  • A lot of controversy surrounds the safety and long-term health effects of artificial sweeteners like sucralose and aspartame. (healthline.com)
  • Recently, a team of Massachusetts General Hospital (MGH) investigators even revealed a potential reason why artificial sweeteners like aspartame prevent, rather than promote, weight loss. (mercola.com)
  • Both athletes and those over age 45 years should take magnesium supplements, antioxidants, omega-3 oils, eat more vegetables and avoid foods and artificial sweeteners containing excitotoxins such as aspartame and MSG. (rense.com)
  • Overall, the best approach is to use aspartame and other artificial sweeteners sensibly and in moderate amounts. (chicagotribune.com)
  • Both aspartame and sucralose are used as artificial sweeteners in place of sugar and both have zero calories. (reference.com)
  • Right now, in the midst of a major childhood obesity epidemic, the giant dairy lobby is trying to force the federal government to redefine "milk" to include artificial sweeteners such as aspartame in children's school lunches without proper labels. (pearltrees.com)
  • With the green light from the FDA and a diet-obsessed nation later, aspartame and other artificial sweeteners have deeply penetrated mainstream diet, with throngs and throngs of believers sending the pro-diabetic, pro-health messages across. (mercola.com)
  • With hopes of striking a responsive chord, I'd like to tell you today: "Sweet" isn't all there is to aspartame and these artificial sweeteners entering your body. (mercola.com)
  • If you're trying to shed the extra pounds and you happen to make a trip to the supermarket, you might have to be more wary of picking out products marketed as "reduced calorie," "sugar-free," and "diet," thus containing aspartame or other artificial sweeteners. (mercola.com)
  • They also found that people who regularly used artificial sweeteners, including aspartame and saccharin, had elevated levels of HbA1C, a measure of blood sugar. (newsmax.com)
  • Artificial sweeteners, including aspartame, are a disaster,' says board-certified family physician Dr. David Brownstein, author of the Natural Way to Health newsletter. (newsmax.com)
  • Artificial Sweeteners: Is Aspartame Safe? (sciencebasedmedicine.org)
  • Response to Indonesian government's action to consider banning aspartame and other artificial sweeteners. (sott.net)
  • Artificial Sweeteners: How Bad Are Saccharin, Aspartame? (time.com)
  • By the Calorie Control Editorial Team Questions about the role of aspartame in weight management continue to provoke controversy, even after 30 plus years of use as an alternative to nutritive sweeteners. (aspartame.org)
  • Some of the concerns about cancer stem from the results of studies in rats published by a group of Italian researchers, which suggested aspartame might increase the risk of some blood-related cancers (leukemias and lymphomas). (cancer.org)
  • A study published by the Ramazzini Foundation in Bologna, Italy, in July 2005 claimed to have shown that rats given dosages of aspartame equivalent to the Acceptable Daily Intake (ADI) may develop tumours. (nationalarchives.gov.uk)
  • The toxicity of aspartame was tested in mice, rats, rabbits and dogs and was found to be very low. (greenfacts.org)
  • These studies were carried out in both humans and laboratory animals and included studies of rats that were fed aspartame in doses greater than 100 times the amount that humans would normally consume. (medicinenet.com)
  • The scientists carried out tests of over 4,000 rats that regularly consumed high doses of aspartame and were allowed to live until they died naturally. (medicinenet.com)
  • In 2005, a rigorous three year study on 1,800 rats concluded that aspartame causes significant increases in lymphoma and leukemia and is a multi-potential carcinogen. (mercola.com)
  • A member of the CIC committee mentioned the rats had infections as relates to the Ramazzini Studies which proved aspartame is a multipotential carcinogen. (rense.com)
  • They also say that while rats fed aspartame ate less food, there was no difference in body weight between treated and untreated animals. (foodnavigator.com)
  • In Searle's original study Dr. Olney found that there was a 47X increase in brain tumors in the rats exposed to high dose aspartame. (redicecreations.com)
  • In a study with mice and rats Toth and Lajtha found that, when giving aspartame and glutamate either as single amino acids or as liquid diets over a prolonged time (several hours to days), they could significantly elevate brain levels of these supposedly excluded excitotoxins. (abovetopsecret.com)
  • In the most recent study, rats were exposed to aspartame in feed at concentrations of either 400 parts per million (ppm) or 2,000 ppm. (foodprocessing.com)
  • For rats in the treatment groups, exposure to aspartame was intended to begin in utero, with aspartame administered via feed to female breeders. (foodprocessing.com)
  • The Ramazzini Foundation interprets the study results as showing a statistically significant increase in the number of cancers in rats consuming aspartame compared to those that did not consume aspartame. (foodprocessing.com)
  • Some experimental studies have not found a connection to brain malignancies and aspartame consumption in rats ( 9 ). (aacrjournals.org)
  • 1] Soffritti M, Belpoggi F, Degli Esposti D, Lambertini L, Tibaldi E, Rigano A. First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. (organicconsumers.org)
  • 2] Soffritti M, Belpoggi F, Tibaldi E, Esposti DD, Lauriola M. Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats. (organicconsumers.org)
  • What are the side effects of aspartame? (medicalnewstoday.com)
  • In 2013, the European Food Safety Authority (EFSA) conducted a review of hundreds of studies looking into the effects of aspartame. (medicalnewstoday.com)
  • The debate has been covered by the media, notably on the Internet where several thousand websites are devoted to the effects of aspartame. (greenfacts.org)
  • It considered more than 500 studies, articles and reports conducted over the last 25 years on the health effects of aspartame, including unpublished works submitted to the Food and Drug Administration and the Department of Health and Human Services for regulatory approvals of the ingredient. (preparedfoods.com)
  • The aim of this article is to demonstrate the direct and indirect role of astrocytes participating in the harmful effects of aspartame metabolites on neurons. (nih.gov)
  • The Center For Science in the Public Interest has a nice review here aspartame about the potential adverse health effects of aspartame. (snack-girl.com)
  • In 1973, Dr. John Olney, M.D. and James Turner, released their findings regarding the toxic effects of aspartame. (lovetoknow.com)
  • The European Food Safety Authority (EFSA) has stated, "Studies do not suggest an increased risk associated with aspartame consumption for… leukaemia, brain tumours or a variety of cancers, including brain, lymphatic and haematopoietic (blood) cancers. (cancer.org)
  • Aspartame has been deemed safe for human consumption by over 100 regulatory agencies in their respective countries, including the United States Food and Drug Administration, UK Food Standards Agency, the European Food Safety Authority (EFSA), Health Canada, Australia, and New Zealand. (wikipedia.org)
  • In December 2013 EFSA published its first full risk assessment of aspartame. (europa.eu)
  • In May 2013, EFSA and the European Commission agreed to extend the timeframe for the Authority's full re-evaluation of aspartame to allow sufficient time to consider and address the feedback, including new information, resulting from the public consultation on its draft opinion. (europa.eu)
  • EFSA therefore launched an additional call for data on DKP and other degradation products of aspartame. (europa.eu)
  • In 2011 and 2013, EFSA updated its opinion on the basis of the most recent studies on aspartame. (greenfacts.org)
  • Is aspartame representing a health risk and where the EFSA conclusions of its previous risk evaluation of aspartame modified? (greenfacts.org)
  • In particular the results of the carcinogenicity study on aspartame conducted in mice in 2010 did not provide a sufficient basis to reconsider the previous evaluations by EFSA. (greenfacts.org)
  • The EFSA ruled aspartame safe for human consumption and set an acceptable daily intake or ADI of aspartame at 40 milligrams (mg) per kilogram (kg) of body weight . (medicalnewstoday.com)
  • The EFSA's ADI for aspartame is 10 mg lower than the amount the FDA consider safe. (medicalnewstoday.com)
  • The European Food Safety Authority (EFSA) reviewed over 600 studies on aspartame in 2013 and found no reason to believe it isn't safe for consumption ( 10 , 18 ). (healthline.com)
  • The European Food Safety Authority (EFSA) announced in April that, "there is no indication of any genotoxic or carcinogenic potential of aspartame. (mercola.com)
  • EFSA claims that the 2005 study by the Ramazzini Foundation (which concluded that aspartame causes significant increases in lymphomas/leukemias and is a multi-potential carcinogen) was "deficient. (mercola.com)
  • "The contribution of breakdown products of aspartame to the overall dietary exposure to these substances is low," ​ EFSA said. (foodnavigator.com)
  • Leading global health authorities such as the European Food Safety Authority (EFSA), FAO/WHO Joint Expert Committee on Food Additives (JECFA), Japan's Ministry of Health, Labor, and Welfare , Food Standards Australia New Zealand and Health Canada have also found aspartame to be safe. (foodinsight.org)
  • The European Food Safety Authority (EFSA) has announced an April 9, 2013, scientific meeting to discuss its draft opinion on the re-evaluation of aspartame (E951). (lexology.com)
  • Lawsuit charges the defendants engaged in unlawful acts of "knowingly and intentionally using the neurotoxic Aspartame as a sugar substitute in the manufacture of Equal, while knowing that exposure to Aspartame causes among other diseases/symptoms. (life-enthusiast.com)
  • We are also astonished by your inclusion of the Calorie Control Council, whose entire purpose is to please their corporate fenders, which include aspartame manufacturers and users, like Coca Cola, Ajinomoto, and the Merisant Corporation, maker of Equal. (indymedia.org)
  • Some headaches have been attributed to aspartame but many chemicals and situations can trigger headaches so that is nothing to get excited about (unless you are the headache sufferer in which case you should avoid aspartame). (opposingviews.com)
  • The University of Maryland Medical Center advises that individuals with the metabolic disorder phenylketonuria, or PKU, should avoid aspartame. (livestrong.com)
  • Additionally, pregnant and breastfeeding women should avoid aspartame and other artificial food additives. (livestrong.com)
  • The controversy over aspartame safety originated in irregularities in the aspartame approval process during the 1970s and early 1980s, including allegations of conflicts of interest and claims that aspartame producer G.D. Searle , a Monsanto subsidiary, had withheld safety data. (sourcewatch.org)
  • Searle had submitted 168 studies [2] (p20) on aspartame, including seven animal studies that were considered crucial by the FDA. (sourcewatch.org)
  • In December 1975, the FDA placed a stay on the aspartame approval, preventing Searle from marketing aspartame. (wikipedia.org)
  • In 1977 and 1978, an FDA task force and a panel of academic pathologists reviewed 15 aspartame studies by Searle, and concluded that, although there were major lapses in quality control, the resulting inconsistencies would not have affected the studies' conclusions. (wikipedia.org)
  • The FDA had actually banned aspartame based on this finding, only to have Searle Chairman Donald Rumsfeld (currently the Secretary of Defense) vow to 'call in his markers,' to get it approved. (rense.com)
  • December 1965-- While working on an ulcer drug, James Schlatter, a chemist at G.D. Searle, accidentally discovers aspartame, a substance that is 180 times sweeter than sugar yet has no calories. (rense.com)
  • Spring 1967-- Searle begins the safety tests on aspartame that are necessary for applying for FDA approval of food additives. (rense.com)
  • Fall 1967-- Dr. Harold Waisman, a biochemist at the University of Wisconsin, conducts aspartame safety tests on infant monkeys on behalf of the Searle Company. (rense.com)
  • Donald Rumsfeld, fresh from the Ford White house went through the revolving door from government to industry to become CEO of the pharmaceutical company, G. D. Searle, owners of the aspartame patent. (prweb.com)
  • Aspartame was discovered in 1965 by a chemist working for the American company Searle and an initial marketing authorisation (MA) was granted in the United States by the Food and Drug Administration ( US-FDA ) in 1974. (greenfacts.org)
  • G.D. Searle spent tens of millions of dollars to conduct the necessary approval tests on aspartame. (mercola.com)
  • Not surprisingly, studies funded by Searle and other groups with a financial interest in aspartame found no adverse health effects. (mercola.com)
  • Aspartame was originally discovered by the American chemical company Searle in 1965. (reference.com)
  • Searle, accidentally discovers aspartame, a substance that is 180 times sweeter than sugar yet has no calories. (pearltrees.com)
  • Donald Rumsfeld was CEO of Searle, the conglomerate that manufactured aspartame. (preventdisease.com)
  • Dr. Arthur Hull Hayes, made FDA Commissioner in exchange for his cooperation, and Samuel Knox Skinner, the attorney hired by the FDA to prosecute Searle for fraud, who then hired on with Searle's public relations firm at $1000 a day: these also assisted in forcing the approval for Aspartame. (sott.net)
  • In 1973, Searle applied to the US Food and Drug Administration (FDA) for approval to market aspartame as a food additive . (coactivate.org)
  • 1. In 1977, former Secretary of Defence (Ford Administration) Donald Rumsfeld was hired as CEO of Searle Laboratories, manufacturer of aspartame, in the hopes his Washington connections could help get aspartame approved by the US Food and Drug Administration. (coactivate.org)
  • 2. Aspartame was initially approved by the FDA in 1974 , one year after Searle applied, but this approval was blocked by various scientific controversies. (coactivate.org)
  • In 1965, a Searle scientist licked some of a new ulcer drug from his fingers and discovered the sweet taste of aspartame. (stevia.net)
  • In December of 1975 the Task force reported serious problem with Searle research on a wide range of products, including aspartame. (stevia.net)
  • It found 11 pivotal studies conducted in a manner so flawed as to raise doubts about aspartame safety and create the possibility of serious criminal liability for Searle. (stevia.net)
  • It is inescapable, however, that the dangers of aspartame cannot be kept from the public forever. (janethull.com)
  • Despite these alarm calls, it's been down to individual scientists to investigate the dangers of aspartame. (healthy.net)
  • Since she had mentioned to me that her goal for the year was to get healthier, she agreed to take a look at some links about the dangers of aspartame. (kellythekitchenkop.com)
  • This is all about dangers of Aspartame. (oocities.org)
  • Did she decide that all the documentation about the dangers of aspartame was not worth passing on to her readers? (janethull.com)
  • TIME.com and Ms. Suddath have just told YOU that aspartame is safe, but they know darn well that it has proven health dangers. (janethull.com)
  • Since 1996, I have been writing about the dangers of aspartame. (janethull.com)
  • There is also Carol Guilford, cookbook author who has been informing people about the dangers of aspartame in her cookbooks for years. (janethull.com)
  • In order to decide for yourself about the potential dangers of aspartame, it's essential to know the facts. (lovetoknow.com)
  • Reviews of the literature have found no consistent findings to support such concerns, and while high doses of aspartame consumption may have some biochemical effects, these effects are not seen in toxicity studies to suggest aspartame can adversely affect neuronal function. (wikipedia.org)
  • To determine the effects of large doses of aspartame on behavior, cognition, and monoamine metabolism in children with attention deficit disorder. (aappublications.org)
  • But more than these, the deceptive studies on aspartame safety are already a distressing truth in themselves. (mercola.com)
  • Recently, new safety studies on aspartame were assessed in the publication "Mutagenicity and genotoxicity studies of aspartame," which recently appeared in Regulatory Toxicology and Pharmacology. (aspartame.org)
  • In 1980, a Public Board of Inquiry (PBOI) heard testimony from Olney and disagreed with his claims that aspartame could cause brain damage, including in the developing fetus. (wikipedia.org)
  • Since its approval, there have been claims that aspartame can cause a variety of illnesses and diseases, including brain tumors, breast cancer, leukemia, lymphoma and lupus. (chicagotribune.com)
  • In February 1984, the U.S. Food and Drug Administration (FDA) requested CDC's assistance in evaluating consumer complaints that FDA had received about consumption of aspartame-containing products. (cdc.gov)
  • Evaluation of dose-response relationships might have been fruitful had individuals reported symptoms with increasingly high consumption of aspartame-containing products. (cdc.gov)
  • Dr. Morando Soffritti told Melanie Warner of the New York Times, 'The NCI's researchers collected no data on people's prior consumption of aspartame or whether they recently began consuming them. (prweb.com)
  • Before we move on to the possible adverse effects that this product can bring to the body, it should be known that FDA allows a person's consumption of aspartame to no more than 50 milligrams. (thegreenguide.com)
  • 1 ) found no relationship between the "Consumption of aspartame-containing beverages and incidence of hematopoietic and brain malignancies" by surveying retired individuals about their consumption of diet sodas and determining whether they had an increase in brain tumors 5 years later. (aacrjournals.org)
  • For those who are dieting, daily consumption of aspartame can be considerably higher. (aacrjournals.org)
  • Aspartame was first discovered in 1965 , but it was several years later when FDA finally provided an approval of its use in carbonated drinks, beverages, and foods. (thegreenguide.com)
  • Discovered by chemist James M. Schlatter in 1965 by pure accident, aspartame and its intrigue-laced approval tells many a tale about corporate America, the contingent blessings brought by the cyclamate and saccharin bans, and the arbiters of government power. (mercola.com)
  • Aspartame was discovered in 1965 and raises a lot of controversy up to date. (nih.gov)
  • Of the seven monkeys that were being fed aspartame mixed with milk, one dies and five others have grand mal seizures. (rense.com)
  • Some pilots have lost their licenses after having experienced seizures from aspartame. (healthy.net)
  • Nonetheless, additional research, including evaluations of possible associations between aspartame and headaches, seizures, behavior, cognition, and mood as well as allergic-type reactions and use by potentially sensitive subpopulations, has continued after approval. (nih.gov)
  • Other concerns of aspartame include headache pain, seizures, mood changes and weight gain, but GreenFacts.org reports that research has shown that aspartame does not increase the risk of these health concerns. (livestrong.com)
  • An enormous number of people have reported serious toxicity reactions from extended use of aspartame including seizures, vision loss, neuropathy symptoms, loss of blood sugar control, nausea, memory loss, depression, and other signs of gradual damage to the body's neurological and immunological systems. (holisticmed.com)
  • As of 1995 more than 7% of the aspartame toxicity reactions reports sent to the U.S. Food and Drug Administration (FDA) involve seizures and convulsions (DHHS 1995). (holisticmed.com)
  • In a study looking at 551 aspartame reactors, Roberts (1988) found that grand mal, petit mal, and absence seizures occurred in 18% of the cases. (holisticmed.com)
  • In 1986, Food and Chemical News reported that 80 cases of aspartame-induced seizures had been reported to Dr. Richard Wurtman at M.I.T. (Food 1986). (holisticmed.com)
  • Walton (1986, 1988) published reports of nine cases of seizures linked to aspartame use. (holisticmed.com)
  • The hypothesis is that this change in brain chemistry will lead to a lowering of the seizure threshold and persons ingesting aspartame will become more susceptible to having seizures. (holisticmed.com)
  • Tollefson inappropriately classified seizures as "Group D -- highly unlikely" related to aspartame if the subjects refused to release their medical records. (holisticmed.com)
  • Skinner went on to become secretary of transportation, squelching cries of the pilots having seizures on this seizure-triggering drug, aspartame, and then chief of staff under G.H.W.Bush. (preventdisease.com)
  • This bill would have put a moratorium on aspartame, and had the NIH do independent studies on the problems being seen in the population, interaction with drugs, seizures, problems with pregnancy, and even behavioral problems in children. (preventdisease.com)
  • Anyone can get on the Worldwide Web and find the research proving that aspartame causes seizures, lymphoma, brain lesions, and leukemia. (janethull.com)
  • With the exception of the risk to those with phenylketonuria, aspartame is considered to be a safe food additive by governments worldwide and major health and food safety organizations. (wikipedia.org)
  • What is phenylketonuria and what is its relationship with aspartame? (greenfacts.org)
  • The second: those who remained ardent fans liked the taste of aspartame, and didn't like sucralose. (wsj.com)
  • Now, PepsiCo says, the Diet Pepsi with aspartame will be carried in U.S. stores along with the sucralose version. (wsj.com)
  • Sucralose vs. Aspartame: What's the Difference? (healthline.com)
  • What's the Difference Between Sucralose and Aspartame? (healthline.com)
  • This article explores the differences between sucralose and aspartame. (healthline.com)
  • Sucralose and aspartame are sugar replacements that are used to sweeten foods or beverages without adding a significant number of calories or carbs. (healthline.com)
  • The difference between aspartame and sucralose is the chemical composition of each compound. (reference.com)
  • Aspartame is made from two amino acids, while sucralose is made by modifying the chemical makeup of sucrose or sugar. (reference.com)
  • The general consensus in the scientific community is that saccharin, aspartame and sucralose are harmless when consumed in moderation. (time.com)
  • Aspartame may also be carcinogenic because at least its metabolite diketopiperazine, can cause cancers in the central nervous system such as gliomas, medulloblastomas and meningiomas. (sourcewatch.org)
  • Furthermore, no new data demonstrated a genotoxic or carcinogenic potential of aspartame. (greenfacts.org)
  • on the basis of all the evidence currently available including the [second] published ERF study there is no indication of any genotoxic or carcinogenic potential of aspartame and that there is no reason to revise the previously established ADI (allowable daily intake) for aspartame of 40mg/kg bw/day. (mercola.com)
  • Aspartame Is An Excitoneurotoxic Carcinogenic Drug! (redicecreations.com)
  • The conclusion was that aspartame did not increase the risk of brain or endocrine dysfunction but that it could be carcinogenic. (lovetoknow.com)
  • People were telling us at the Conference of the American College of Physicians, that they had relatives that switched from saccharin to an aspartame product and how that relative had eventually gone into a coma. (spiritual-endeavors.org)
  • Like many other peptides , aspartame may hydrolyze (break down) into its constituent amino acids under conditions of elevated temperature or high pH . (wikipedia.org)
  • Aspartame is a simple compound made from two amino acids and a methyl group, all of which occur naturally in the diet and are consumed in larger amounts from other normal dietary sources. (foodnavigator.com)
  • Although wood alcohol naturally occurs in some of the foods that we eat, it doesn't come naturally bound to amino acids as it does in aspartame. (drbenkim.com)
  • A can of diet soda, for example, contains only about 190 mg of aspartame. (medicalnewstoday.com)
  • For further context, one 12-ounce (355-ml) can of diet soda contains about 180 mg of aspartame. (healthline.com)
  • The study found drinking aspartame-sweetened diet soda daily increased the risk of type 2 diabetes by 67 percent (regardless of whether they gained weight or not) and the risk of metabolic syndrome 36 percent. (mercola.com)
  • Before you add another spoonful of aspartame to your coffee or chug another diet soda, however, consider aspartame's impact on diets that induce ketosis. (livestrong.com)
  • If you normally are a big diet-soda drinker, or ingest other products with aspartame, cut them ALL out for 4 weeks. (bellaonline.com)
  • Diet soda, aspartame linked to premature deaths in women. (pearltrees.com)
  • NaturalNews) A decade-long study of 60,000 women has confirmed that drinking diet soda sweetened with aspartame is linked with a 30 percent increase in heart attack risk and a 50 percent increase in death risk. (pearltrees.com)
  • In a nutshell, she was being poisoned by the Aspartame in the diet soda. (grinnell.edu)
  • For a person weighing 150 pounds (68 kg), this equates to 3,400 mg of aspartame - the amount found in 19 cans of diet soda or more than 100 individual packets of aspartame - consumed, on average, every day over a lifetime. (foodinsight.org)
  • study assumed that the average daily intake of aspartame was equivalent to approximately one 12-oz. can of diet soda and did not include products, such as table sugars, candies, yogurt, nutrition bars, and even chewing gum ( 2 ). (aacrjournals.org)
  • I drink alot of diet soda drinks daily and have done for years, I've always known they are not healthy and I have heard of aspartame before, but never really knew to much about it. (abovetopsecret.com)
  • At the end of last year Coca Cola introduced Coke Life (an interesting choice of name from my perspective as a health coach), a new diet soda that replaces aspartame with stevia and sugar . (kellythekitchenkop.com)
  • I think a lot of diet soda drinkers want to give up aspartame, but don't… or can't. (kellythekitchenkop.com)
  • Just read the shocking 7-DAY DETOX ASPARTAME WITHDRAWAL SYMPTOMS of a 42-year-old addict with a 5-8 can per day habit for 25 years (not unusual by the way, many diet soda drinkers start as teenagers). (kellythekitchenkop.com)
  • Part of the first generation of these is aspartame, which is 180 times sweeter than sugar. (mercola.com)
  • However, because aspartame is much sweeter than sugar, very little is needed in foods and beverages to match the sweetness provided by sugar. (foodinsight.org)
  • Aspartame was seen as a good substitute - and one that packed a kick for all those with a sweet tooth, as it is 200 times sweeter than sugar. (healthy.net)
  • As it is 200 times sweeter than sugar, only tiny amounts of aspartame are needed to achieve the desired sweetness, reducing the number of calories compared with sugar. (aspartame.org)
  • Criteria originally developed to assess potential adverse reactions to medications were adapted to evaluate the likelihood that symptoms reported by individuals through this passive surveillance system could be due to aspartame consumption (1,2). (cdc.gov)
  • An important criterion in assessing potential adverse reactions is the consistency of reported symptoms with rechallenge, i.e., the recurrence of symptoms after consuming aspartame-containing products a second time. (cdc.gov)
  • But animal studies have revealed that aspartame can cause adverse reactions and conditions, some of which could be life threatening. (opposingviews.com)
  • The suggestions of adverse effects from aspartame consumption have absolutely no credible scientific basis," said William J. Waddell, MD, Professor and Chair, Emeritus, Toxicology, at the University of Louisville School of Medicine, who chaired the panel. (preparedfoods.com)
  • Aspartame has not been shown to have adverse effects on reproductive activity or lactation. (medindia.net)
  • What I did find was that FD&C dyes (not aspartame) are the food additives most frequently associated with adverse reactions. (sciencebasedmedicine.org)
  • Even so, aspartame accounts for more than 75 per cent of adverse reactions to food reported every year to the Food and Drug Administration (FDA). (healthy.net)
  • That study -"Adverse Reactions to Aspartame: Double- Blind Challenge in Patients from a Vulnerable Population" was published in Biological Psychiatry in 1993. (wellnesscenter.net)
  • In 1996, the controversy reached a wider audience with a 60 Minutes report [23] on concerns that aspartame could cause brain tumors in humans. (sourcewatch.org)
  • I have heard so much controversy regarding aspartame (found in diet drinks) and MS. I was wondering what thoughts anyone had on this matter? (dailystrength.org)
  • I will comment however on one aspect of the aspartame controversy. (opposingviews.com)
  • Sayer Ji, ContributorActivist Post A new study on aspartame has the potential to reignite the decades-old controversy behind this artificial sweetener's safety, or lack thereof. (pearltrees.com)
  • To understand the sordid realities surrounding the release of aspartame into U.S. food and pharmaceutical use, one has to appreciate that controversy surrounded aspartame almost from its very beginning when the U.S. FDA's own scientists would not recommend it. (activistpost.com)
  • There is a lot of controversy as to whether or not aspartame should be avoided by people with ADHD/ADD. (hubpages.com)
  • From the time aspartame received FDA approval in 1973, there has been controversy surrounding its safety. (lovetoknow.com)
  • It's unlikely that the controversy over aspartame will ever go away. (lovetoknow.com)
  • When an excess of food-borne excitotoxins, such as MSG, hydrolyzed protein, soy protein isolate and concentrate, natural flavoring, sodium caseinate and aspartate from aspartame, are consumed, these glutamate receptors are over stimulated, producing cardiac arrhythmias. (rense.com)
  • A number of studies have shown that consuming aspartame and MSG (and similar excitotoxins) together greatly magnifies the toxicity. (rense.com)
  • This is thought to occur because both aspartame and MSG are "excitotoxins" that can trigger excess activity in a nervous system called NMDA. (livestrong.com)
  • His laboratory studies had demonstrated that high dose aspartame could cause the very same brain injury as other excitotoxins. (redicecreations.com)
  • It is not unreasonable to assume that mothers will eat several meals and snacks containing various forms of excitotoxins such as MSG, hydrolyzed vegetable protein, and aspartame. (abovetopsecret.com)
  • 3) Excitotoxins -- aspartame, monosodium glutamate and others (see below). (100777.com)
  • The elimination of MSG, Aspartame and other excitotoxins from the diets of patients with fibromyalgia is a successful treatment option. (greenmedinfo.com)
  • The risk of experiencing nerve cell death from ingesting too much aspartame is higher in people who smoke, have high blood pressure, or have diabetes, as all of these factors potentially increase the permeability of the blood-brain barrier that is supposed to protect your nerve cells against excitotoxins. (drbenkim.com)
  • [7] [8] A 2011 study showed that aspartame exposure increases blood glucose levels and therefore ups the risk of diabetes in humans. (sourcewatch.org)
  • Overall, there is no conclusive evidence to suggest that aspartame increases the risk of cancer in humans. (healthline.com)
  • The Acceptable Daily Intake ( ADI ) of aspartame for humans was fixed at 40 mg/kg body weight/day by the JECFA (1980). (greenfacts.org)
  • Both published and unpublished data, including all the information on genotoxicity and carcinogenicity in animals and humans, were considered at that time and the SCF re-confirmed the previously established acceptable daily intake (ADI) for aspartame. (foodnavigator.com)
  • Even though the tests were poorly conducted they did demonstrate that aspartame was associated with a dramatic, dose-dependent, increase in a variety of brain tumors-mainly astrocytomas-the type commonly seen in humans. (redicecreations.com)
  • The possible effect of full lifetime and prenatal exposures on humans of aspartame cannot be evaluated in the Lim et al. (aacrjournals.org)
  • A panel of experts set up by the European Food Safety Authority concluded in 2013 that aspartame is safe for human consumption at current levels of exposure. (wikipedia.org)
  • The current Acceptable Daily Intake (ADI) of 40mg/kg bw/day is considered protective for the general population and consumer exposure to aspartame is well below this ADI. (europa.eu)
  • Conservative estimates of exposure to aspartame made by the Panel for the general population were up to 36 mg/kg bw/day at the 95th percentile (the highest consumers), thus below the ADI. (greenfacts.org)
  • The duration of exposure to aspartame is inadequate in the study. (prweb.com)
  • Enough exposure to aspartame can lead to nerve cell death. (drbenkim.com)
  • Issued by the agency's Scientific Panel on Food Additives and Nutrient Sources Added to Food (ANS Panel), the re-evaluation declined to revise the current Acceptable Daily Intake (ADI) for aspartame after concluding that the substance and its breakdown products "pose no toxicity concern for consumers at current levels of exposure. (lexology.com)
  • Aspartame is approximately 200 times sweeter than sucrose (table sugar). (wikipedia.org)
  • Aspartame is around 180 to 200 times as sweet as sucrose (table sugar). (wikipedia.org)
  • the sweetness of aspartame has a slower onset and longer duration than that of sucrose, and some consumers find it unappealing. (newworldencyclopedia.org)
  • Though aspartame has the same number of calories as sugar on a weight-to-weight basis, it can be added to food or pharmaceuticals at a fraction of what would be needed with sucrose to achieve the same sweetness, with far fewer calories. (medindia.net)
  • The sweetness of aspartame is between 180 and 200 times sweeter than sucrose. (physicsforums.com)
  • That means to get the same sweetness you add about .5% as much aspartame as you do sucrose. (physicsforums.com)
  • In this study, the children spent 40% more time in spike wave after aspartame than after sucrose. (holisticmed.com)
  • Aspartame also includes phenylalinine, which causes PKU in a small number of susceptible children, and methyl, or wood, alcohol which is neurotoxic in large amounts. (stevia.net)
  • The results of epidemiologic studies (studies of groups of people) of possible links between aspartame and cancer (including blood-related cancers) have not been consistent. (cancer.org)
  • The Panel noted there was no epidemiological evidence for possible association of aspartame with various cancers in the human population . (greenfacts.org)
  • This, despite the overwhelming evidence aspartame caused brain and breast cancers in Searle's experimental testing. (prweb.com)
  • An FDA investigation of Searle's cover-up of the cancers caused by aspartame was conducted by Dr. Jerome Bressler of the FDA. (prweb.com)
  • The American Diabetes Association states that there is no evidence that shows a connection between aspartame and an increased risk of cancers. (livestrong.com)
  • In February the agency's Dietary Guidelines Advisory Committee reiterated its stance, although it mentioned a 'possible association' between aspartame and the risk of some blood cancers, such as non-Hodgkins lymphoma. (newsmax.com)
  • No correlation was found between aspartame consumption and risk of these cancers over a 15-year period. (foodprocessing.com)
  • Soffritti's September 2007 publication ( 10 ) supported the 2005 ( 11 ) experiment that found an obvious association between aspartame and multiple types of cancers. (aacrjournals.org)
  • Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice. (organicconsumers.org)
  • In America today, more than 10 million children regularly consume sodas and other foods containing aspartame. (aacrjournals.org)
  • In the case of aspartame, the ADI is set at 40 milligrams per kilogram of body weight. (nationalarchives.gov.uk)
  • In the case of aspartame use, because few of the complainants sought medical aid, few physician reports containing information specific to the aspartame complaints were available. (cdc.gov)
  • There have been concerns from the beginning, however, that consuming synthetic compounds with hyper-sweetness (200 times that of sugar in the case of aspartame) has some serious drawbacks. (mercola.com)
  • In fact, studies show that even diabetics, people who are high in blood sugar level, which is most likely caused by abnormal intake of sugar, don't have exceeding levels of aspartame in their blood. (thegreenguide.com)
  • The panel used the latest data from the National Health and Nutrition Examination Surveys (NHANES) to determine the most current levels of aspartame consumption. (medindia.net)
  • 1.1 What is the history of aspartame? (greenfacts.org)
  • History of Aspartame Frequently Asked Questions (FAQs) report. (holisticmed.com)
  • Aspartame has a very convoluted history, and what you read on the Internet and in my book Sweet Poison about the history of aspartame is true. (janethull.com)
  • So, here we are decades later, still trying to get the truth about aspartame public. (janethull.com)
  • This article has turned the spotlight on the public manipulation of the truth about aspartame, and it shows the one-sided spin of propaganda concerning aspartame safety. (janethull.com)
  • It was recognized from the outset that this investigation alone would be unlikely to establish any cause-and-effect relationship between the ingestion of aspartame and the occurrence of reported symptoms. (cdc.gov)
  • Moreover, details relating to the time between ingestion of aspartame and onset of symptoms often were incomplete because aspartame consumption was part of the daily routine. (cdc.gov)
  • The current wholesale ingestion of aspartame products by over half the adult population constitutes an imminent public health hazard. (life-enthusiast.com)
  • Several studies have researched the connection between aspartame consumption and cancer. (healthline.com)
  • The board decided that further study was needed on a postulated connection between aspartame and brain tumors, and revoked approval of aspartame. (wikipedia.org)
  • As of 2018, several reviews of clinical trials showed that using aspartame in place of sugar reduces calorie intake and body weight in adults and children. (wikipedia.org)
  • A 2017 review of metabolic effects by consuming aspartame found that it did not affect blood glucose, insulin, total cholesterol, triglycerides, calorie intake, or body weight, while high-density lipoprotein levels were higher. (wikipedia.org)
  • Like many food additives, the safety assessment for aspartame has led to the setting of an Acceptable Daily Intake, or ADI. (nationalarchives.gov.uk)
  • this report does not consider the possible intake (very limited compared with dietary intake) of aspartame from this later source. (greenfacts.org)
  • Aspartame intake has also been shown to increase your risk of breast or prostate cancer . (mercola.com)
  • The food safety body concluded that the current ADI (acceptable daily intake) of aspartame - 40 mg per kg of bodyweight per day - was protective for the general population. (foodnavigator.com)
  • As part of its review, the panel applied the most recent food consumption survey information to estimate current aspartame intake. (preparedfoods.com)
  • Even the very highest consumers of aspartame are well below the acceptable daily intake (ADI) and well below the amounts used in animal testing," said Magnuson. (medindia.net)
  • The FDA recommends a daily intake of no more than 50 mg of aspartame per kilogram of body weight. (cnn.com)
  • The FDA established an acceptable daily intake (ADI) for aspartame of 50 milligrams per kilogram of body weight (mg/kg) per day. (foodinsight.org)
  • In people who report consuming aspartame, the estimated average intake is 4.9 mg/kg per day, which is less than 10 percent of the FDA's ADI ( Magnuson 2007 ). (foodinsight.org)
  • For those in the 95th percentile of aspartame consumption, intake is estimated at 13.3 mg/kg per day - still far below the ADI. (foodinsight.org)
  • Globally, aspartame intake also remains well below the ADI - a 2018 study noted that only in rare instances did individuals exceed more than 20 percent of the ADI, even in the highest-consuming groups ( Martyn 2018 ). (foodinsight.org)
  • a child weighing 30 kg (∼66 lb) with a similar daily intake would have an aspartame daily dose twice as high-30.3 mg/kg of body weight ( 4 ). (aacrjournals.org)
  • For instance, the South Beach Diet attempts to eliminate sugar intake by endorsing the extensive use of sugar substitutes, such as aspartame ( 5 ). (aacrjournals.org)
  • This increase coincided with approval of aspartame for use in soft drinks in July 1983. (cdc.gov)
  • From the clinical studies performed before FDA approval of aspartame, there was little to suggest that acute reactions would be likely to occur. (cdc.gov)
  • In 1987, the U.S. Government Accountability Office concluded that the food additive approval process had been followed properly for aspartame. (wikipedia.org)
  • July 26, 1974-- The FDA grants aspartame its first approval for restricted use in dry foods. (rense.com)
  • Dr. Olney's research, released in 1996, showed significant brain tumor increases since the approval of aspartame. (prweb.com)
  • In an August 4, 2010 Huffington Post article, physician and author Dr. Joseph Mercola blasts aspartame as a deadly neurotoxin, citing episodes from its hard-won battle for U.S. Food and Drug Administration approval and numerous clinical studies linking it to brain cancer. (livestrong.com)
  • The approval process for aspartame was riddled with scandal, bribes and other shady dealings within the pharmaceutical industry, large American corporations, and the FDA. (mercola.com)
  • In 1992, Dr. Olney published a study that suggested that the significant rise in human brain tumors was related to the widespread use of aspartame, since it began after the approval of aspartame in foods and beverages. (redicecreations.com)
  • During the FDA approval process, a number of government officials were rewarded with jobs connected to the aspartame industry (GAO 1986). (holisticmed.com)
  • Dr.Martinni noted: "The FDA set up a board of inquiry of the best scientists they had to offer, who said aspartame is not safe and causes brain tumors, and the petition for approval is hereby revoked. (preventdisease.com)
  • Approval of aspartame in carbonated beverages followed in July 1983. (baltimoresun.com)
  • Arthur Hull Hayes, blackmailed to sign the aspartame approval. (earthrainbownetwork.com)
  • As a sugar substitute, aspartame stimulates the taste buds on the tongue in the same way as sugar. (healthline.com)
  • Psychiatry in 1993, and the drug it denounced was aspartame , the widely used sugar substitute. (thefreedictionary.com)
  • September 30 Medical Letter on the CDC & FDA -- A new review of aspartame research -- the most comprehensive ever conducted -- once again has concluded the widely used sugar substitute is safe, even among its heaviest users. (preparedfoods.com)
  • A typical 12 ounce low-calorie soft drink will have 180 milligrams of aspartame in it. (scitoys.com)
  • In actual fact, the information released from the study states only…"there was no cancer link to those who consumed 400 milligrams of aspartame, about 2 cans of soda daily. (prweb.com)
  • For instance, a 12 oz of soda contains 0.0063 oz or 180 milligrams of aspartame. (thegreenguide.com)
  • Encouragement that the relevant and responsible medical and judicial authorities make this ban permanent, based on sound medical evidence that aspartame causes neurodegenerative illnesses like brain tumors and multiple sclerosis, and even worse illnesses. (sott.net)
  • In 1995 and 1996, misinformation about aspartame that linked the chemical to everything from multiple sclerosis to Gulf War syndrome was widely disseminated on the Internet. (time.com)
  • The request followed an increase in aspartame-related complaints in the latter half of 1983. (cdc.gov)
  • In November 1983 the FDA approved aspartame for soft drinks - Hayes' last decision. (activistpost.com)
  • The testimony of the Center for Science in the Public Interest was helpful in that they knew of the misinformation of the European Food Safety Authority review that sugarcoated aspartame as "safe" and warned not to consider it. (rense.com)
  • May 8, 2018 - A recent peer-reviewed article evaluated the reliability of the available literature investigating possible links between aspartame and cancer and the results are in: studies linking aspartame to cancer scored as "not reliable" according to an internationally recognized grading system for scientific research. (aspartame.org)
  • My other reason for not drinking it was that I had heard once about 15 years ago that Aspartame may be linked to brain cancer. (dailystrength.org)
  • When Olney and his colleagues fed aspartame to immature mice, they found it destroyed the nerve cells in the brain. (prweb.com)
  • In 1996, an article by J.W. Olney suggesting a link between an increased incidence of brain tumours in the United States and the marketing of aspartame relaunched the debate on the risks to human health posed by its consumption. (greenfacts.org)
  • The panel also said there was no risk to the developing foetus from aspartame consumption, and that aspartame does not harm the brain, nervous system or cognitive function in children or adults. (foodnavigator.com)
  • Aspartame: Approved In 90 Nations, But Damages Brain. (pearltrees.com)
  • Dr. Adrian Gross, the FDA's own toxicologist, testified before Congress that without a shadow of a doubt, aspartame can cause brain tumors and brain cancer. (patientslikeme.com)
  • There was also some discussion that aspartame causes brain tumours, but that's a claim generally rejected by researchers as having no validity. (healthboards.com)
  • That means every bit of aspartame or MSG you ingest has free reign to get your pain receptors worked into a frenzy, sending a whole bunch of extra pain signals to your brain. (medhelp.org)
  • In the 1990s a researcher suggested that rates of brain cancer seemed to surge at about the same time aspartame was introduced here. (cnn.com)
  • Many researchers have linked a host of health problems, including brain diseases, migraines and neurological ailments to Aspartame. (greenmedinfo.com)
  • This study examined the eating habits of about a half a million older Americans and compared the occurrence of lymphoma, leukemia and brain cancer among consumers and non-consumers of aspartame-containing beverages. (foodprocessing.com)
  • FDA toxicologist Dr. Adrian Gross testified to congress that aspartame caused tumors and brain cancer in lab animals and therefore violated the Delaney Amendment that forbids putting anything in food that is know to cause cancer. (preventdisease.com)
  • Both Indonesia and South Africa are leading the world in firmly moving towards prohibiting this chemical for medical reasons: aspartame is an excitotoxin and causes brain damage. (sott.net)
  • Up till 1995, the FDA kept a continually growing list of consumer complaints about aspartame, and the fact that it caused brain tumors, headaches, memory loss, cardiac arrythmia, sudden death, a total of 92 symptoms. (sott.net)
  • 6] Olney JW, Farber NB, Spitznagel E, Robins LN. Increasing brain tumor rates: is there a link to aspartame? (organicconsumers.org)
  • Increasing brain tumor rates: Is there a link to aspartame? (rti.org)
  • In October 1980 the Public Board of Inquiry (PBOI) impaneled by the FDA to evaluate aspartame safety found that the chemical caused an unacceptable level of brain tumors in animal testing. (stevia.net)
  • Anyone can get on the Internet and read the research proving aspartame is a carcinogen, a brain toxin, and that aspartame has been proven to cause fetal deformities. (janethull.com)
  • why an angry parent of a child with a deformed cleft palate or born with a brain lesion wonders why she was told, and read , that aspartame was perfectly safe during pregnancy. (janethull.com)
  • The board was tasked with determining if aspartame can lead to brain damage or tumors. (lovetoknow.com)
  • Below are more details about these three breakdown products of aspartame. (healthline.com)
  • The opinion concludes that aspartame and its breakdown products are safe for general population (including infants, children and pregnant women). (europa.eu)
  • Examples of neuroexcitatory toxins in high concentrations are monosodium glutamate, also known as MSG and components or breakdown products of aspartame. (healthy.net)
  • Aspartame is a toxin, it's poison as far as I'm concerned and although I was not a big diet coke fan, it was the only soda I would drink. (dailystrength.org)
  • I told Monsanto years ago they could make just as much money selling aspartame as a rat poison, just change the label. (rense.com)
  • Www.relfe.com/2010/aspartame_ant_cockroach_poison.html. (pearltrees.com)
  • See What Ants Do To Aspartame Using Aspartame for Ant & Cockroach Poison by Stephanie Relfe B.Sc. (pearltrees.com)
  • Sydney) July 22 2010 I had heard of a woman who made up ant poison from aspartame, and since we in Florida were being invaded by ants, I decided to make up some ant poison of my own. (pearltrees.com)
  • If you seriously think aspartame isn't poison, just drink it up little sheeple - we're better off without you. (abovetopsecret.com)
  • I honestly thought all the 'aspartame is poison' talk was a bunch of crap, but after this experience I am probably done with it for life. (anabolicminds.com)
  • In addition, Dr. Janet Hull has written about aspartame in her book, Sweet Poison . (janethull.com)
  • but, if you google it you can see that where there's vanillin in a list of ingredients, 99% of the time aspartame is right there next to it - but they don't always tell you that. (abovetopsecret.com)
  • When exposed to high temperatures or simply stored for a long period of time, aspartame breaks down into a few different compounds, one of which is aspartylphenylalanine diketopiperazine (DKP). (drbenkim.com)
  • [16] In products such as powdered beverages , the amine in aspartame can undergo a Maillard reaction with the aldehyde groups present in certain aroma compounds . (wikipedia.org)
  • In the course of its scientific deliberations, the Panel found that there were too little data available on 5-benzyl-3,6-dioxo-2-piperazine acetic acid (DKP) and other potential degradation products that can be formed from aspartame in food and beverages when stored under certain conditions. (europa.eu)
  • Aspartame is an ingredient in approximately 6,000 consumer foods and beverages sold worldwide. (newworldencyclopedia.org)
  • The NSDA wrote a 33 page protest against using aspartame in carbonated beverages, then turned around and lobbied for the manufacturer. (rense.com)
  • estimated average daily aspartame consumption values based solely on the consumption of beverages containing aspartame. (aacrjournals.org)
  • states that 70% of consumed aspartame is obtained through diet beverages, citing the American Dietetic Association as the source of this information. (aacrjournals.org)
  • By 1998, aspartame products were the cause of 80% of complaints to the FDA about food additives. (sourcewatch.org)
  • Aspartame was originally approved for use in dry foods in 1974 by then FDA Commissioner Alexander Schmidt after review by the FDA's Center for Food Safety and Applied Nutrition. (sourcewatch.org)
  • Aspartame is one of the most rigorously tested food ingredients. (wikipedia.org)
  • Aspartame was first approved in the UK in 1982 following the review of its safety by the UK's Committee on Toxicity, Consumer Products and the Environment (COT), a committee of independent experts that advises the Government on the safety of food chemicals. (nationalarchives.gov.uk)
  • Instead legislation on food additives specifies the categories of foods in which aspartame can be used and the levels that can be added. (nationalarchives.gov.uk)
  • FDA officials describe aspartame as "one of the most thoroughly tested and studied food additives the agency has ever approved" and its safety as "clear cut. (wikipedia.org)
  • Most of the food items in which aspartame is authorised are subject to limitations. (greenfacts.org)
  • Michael Jacobson, of the CSPI, (Center for Science in the Public Interest) admits about the AARP study…"the new study's means of measuring aspartame consumption-food-frequency questionnaires, is imprecise. (prweb.com)
  • The safety testing of aspartame has gone well beyond that required to evaluate the safety of a food additive. (nih.gov)
  • Slick marketing of products containing aspartame by giants in the food industry -- especially marketing that sends the message it's healthy to consume these products - have been brainwashing and lulling consumers into a false sense of security for decades. (mercola.com)
  • Unlike other food substitutes such as the artificial fat olestra , aspartame is digested by your body. (howstuffworks.com)
  • "This opinion represents one of the most comprehensive risk assessments of aspartame ever undertaken," ​ said the chair of EFSA's Panel on Food Additives and Nutrient Sources Added to Foods (ANS Panel), Dr Alicja Mortensen. (foodnavigator.com)
  • A further review of all the original and more recent data on aspartame was carried out in 2002 by the EC Scientific Committee for Food. (foodnavigator.com)
  • The study notes that patients with a chronic pain disorder called fibromyalgia, or FM, showed improved symptoms after completely removing aspartame and a food additive called monosodium glutamate, or MSG, from their diet. (livestrong.com)
  • Because aspartame use has increased dramatically over the years, the panel made a special effort to review the most up-to-date consumption data," said Bernadene A. Magnuson, PhD, a University of Maryland food toxicologist who coordinated the panel for the Burdock Group of Vero Beach, Florida. (preparedfoods.com)
  • He completely lied about the truth of what Aspartame can do to the human body, and in turn said that it was "the most studied food additive. (infowars.com)
  • GM Aspartame is not only used in food, per se, but is also used in pharmaceutical products. (responsibletechnology.org)
  • So, how did aspartame get into food and pharmaceuticals? (activistpost.com)
  • Still, the Food and Drug Administration insists aspartame is safe. (newsmax.com)
  • How dangerous is food containing aspartame? (cnn.com)
  • The Food and Drug Administration has concluded that aspartame is safe, and there are no strong data out there to refute that. (cnn.com)
  • The FDA stopped accepting aspartame toxicity reaction reports in 1995 (Food 1995). (holisticmed.com)
  • Aspartame and L-glutamic acid work synergistically with food coloring agents to induce neurotoxicity. (greenmedinfo.com)
  • Aspartame receives an extraordinary amount of attention from conspiracy theorists and those who are generally apprehensive about food safety and the food industry. (foodprocessing.com)
  • Whether or not FDA attempts a complete review of Ramazzini's latest study, aspartame is already the most scrutinized food additive present in the diet. (foodprocessing.com)
  • Unfortunately, certain consumers will remain distrustful of aspartame and will regard any honest and straightforward discussion of its safety as being inappropriately influenced by the food industry. (foodprocessing.com)
  • STOP drinking diet sodas and be alert for Aspartame on food labels! (grinnell.edu)
  • ADHD is often said to be inherited just like PKU, and many parents swear that their child's hyperactivity is made worse soon after the child has had food containing aspartame. (hubpages.com)
  • Aspartame is one of the most exhaustively studied substances in the human food supply, with over 200 studies supporting its safety. (foodinsight.org)
  • What brilliant news, that the Indonesian Drug and Food Monitoring Agency is considering considering banning aspartame! (sott.net)
  • Of the 8,500 food-additive complaints received by the Food and Drug Administration since 1984 when monitoring began, 6,000 have been about aspartame. (baltimoresun.com)
  • Anyone "in the know" has known since the late 1960s that aspartame is a dangerous food toxin. (janethull.com)
  • But sadly, aspartame was approved and put into the public food supply anyway. (janethull.com)
  • Aspartame had been approved in the States two years earlier as a safe food additive. (healthy.net)
  • Snack Girl is on the case with two different gums that don't include aspartame or artificial colors (see the article F.D.A. Panel to Consider Warnings for Artificial Food Colorings, March 29th, 2011 ). (snack-girl.com)
  • it loses flavor a little quicker than most gum but definitely another aspartame-free option and it's sold at Whole Foods and other natural health food stores, I believe. (snack-girl.com)
  • Based on this fact, the PBOI ruled that aspartame should not be added to the food supply. (stevia.net)
  • February 7, 2019 - Aspartame is one of the most studied ingredients in our food supply, but it is also one of the most controversial. (aspartame.org)
  • By Rosanne Rust MS, RDN, LDN - Aspartame allows food manufacturers to create many delicious and innovative low-calorie products, which help support weight control efforts and a healthy lifestyle. (aspartame.org)