American Native Continental Ancestry Group: Individuals whose ancestral origins are in the continents of the Americas.Asian Continental Ancestry Group: Individuals whose ancestral origins are in the southeastern and eastern areas of the Asian continent.African Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Africa.European Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Europe.Oceanic Ancestry Group: Individuals whose ancestral origins are in the islands of the central and South Pacific, including Micronesia, Melanesia, Polynesia, and traditionally Australasia.Asian Americans: Persons living in the United States having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent.Asia: The largest of the continents. It was known to the Romans more specifically as what we know today as Asia Minor. The name comes from at least two possible sources: from the Assyrian asu (to rise) or from the Sanskrit usa (dawn), both with reference to its being the land of the rising sun, i.e., eastern as opposed to Europe, to the west. (From Webster's New Geographical Dictionary, 1988, p82 & Room, Brewer's Dictionary of Names, 1992, p34)Genealogy and HeraldryPolymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.Genetics, Population: The discipline studying genetic composition of populations and effects of factors such as GENETIC SELECTION, population size, MUTATION, migration, and GENETIC DRIFT on the frequencies of various GENOTYPES and PHENOTYPES using a variety of GENETIC TECHNIQUES.Ethnic Groups: A group of people with a common cultural heritage that sets them apart from others in a variety of social relationships.Genome-Wide Association Study: An analysis comparing the allele frequencies of all available (or a whole GENOME representative set of) polymorphic markers in unrelated patients with a specific symptom or disease condition, and those of healthy controls to identify markers associated with a specific disease or condition.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Asia, Southeastern: The geographical area of Asia comprising BORNEO; BRUNEI; CAMBODIA; INDONESIA; LAOS; MALAYSIA; the MEKONG VALLEY; MYANMAR (formerly Burma), the PHILIPPINES; SINGAPORE; THAILAND; and VIETNAM.Haplotypes: The genetic constitution of individuals with respect to one member of a pair of allelic genes, or sets of genes that are closely linked and tend to be inherited together such as those of the MAJOR HISTOCOMPATIBILITY COMPLEX.Gene Frequency: The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION.African Americans: Persons living in the United States having origins in any of the black groups of Africa.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Genetic Variation: Genotypic differences observed among individuals in a population.Indians, South American: Individual members of South American ethnic groups with historic ancestral origins in Asia.Gene Pool: The total genetic information possessed by the reproductive members of a POPULATION of sexually reproducing organisms.Adie Syndrome: A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)Far East: A geographic area of east and southeast Asia encompassing CHINA; HONG KONG; JAPAN; KOREA; MACAO; MONGOLIA; and TAIWAN.Genetic Loci: Specific regions that are mapped within a GENOME. Genetic loci are usually identified with a shorthand notation that indicates the chromosome number and the position of a specific band along the P or Q arm of the chromosome where they are found. For example the locus 6p21 is found within band 21 of the P-arm of CHROMOSOME 6. Many well known genetic loci are also known by common names that are associated with a genetic function or HEREDITARY DISEASE.Trinidad and Tobago: An independent state in the Lesser Antilles in the West Indies, north of Venezuela, comprising the islands of Trinidad and Tobago. Its capital is Port of Spain. Both islands were discovered by Columbus in 1498. The Spanish, English, Dutch, and French figure in their history over four centuries. Trinidad and Tobago united in 1898 and were made part of the British colony of Trinidad and Tobago in 1899. The colony became an independent state in 1962. Trinidad was so named by Columbus either because he arrived on Trinity Sunday or because three mountain peaks suggested the Holy Trinity. Tobago was given the name by Columbus from the Haitian tambaku, pipe, from the natives' habit of smoking tobacco leaves. (Webster's New Geographical Dictionary, 1988, p1228, 1216 & Room, Brewer's Dictionary of Names, 1992, p555, 547)Alleles: Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.Hispanic Americans: Persons living in the United States of Mexican (MEXICAN AMERICANS), Puerto Rican, Cuban, Central or South American, or other Spanish culture or origin. The concept does not include Brazilian Americans or Portuguese Americans.Linkage Disequilibrium: Nonrandom association of linked genes. This is the tendency of the alleles of two separate but already linked loci to be found together more frequently than would be expected by chance alone.Product Surveillance, Postmarketing: Surveillance of drugs, devices, appliances, etc., for efficacy or adverse effects, after they have been released for general sale.Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.JapanAdverse Drug Reaction Reporting Systems: Systems developed for collecting reports from government agencies, manufacturers, hospitals, physicians, and other sources on adverse drug reactions.Fat Substitutes: Compounds used in food or in food preparation to replace dietary fats. They may be carbohydrate-, protein-, or fat-based. Fat substitutes are usually lower in calories but provide the same texture as fats.Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.Clinical Trials, Phase IV as Topic: Planned post-marketing studies of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques that have been approved for general sale. These studies are often conducted to obtain additional data about the safety and efficacy of a product. This concept includes phase IV studies conducted in both the U.S. and in other countries.Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.Polymorphism, Genetic: The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.Urinary Bladder: A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.China: A country spanning from central Asia to the Pacific Ocean.Genetic Association Studies: The analysis of a sequence such as a region of a chromosome, a haplotype, a gene, or an allele for its involvement in controlling the phenotype of a specific trait, metabolic pathway, or disease.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Paternity: Establishing the father relationship of a man and a child.Chromosomes, Human, Y: The human male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in humans.Tandem Repeat Sequences: Copies of DNA sequences which lie adjacent to each other in the same orientation (direct tandem repeats) or in the opposite direction to each other (INVERTED TANDEM REPEATS).Forensic Genetics: The application of genetic analyses and MOLECULAR DIAGNOSTIC TECHNIQUES to legal matters and crime analysis.Microsatellite Repeats: A variety of simple repeat sequences that are distributed throughout the GENOME. They are characterized by a short repeat unit of 2-8 basepairs that is repeated up to 100 times. They are also known as short tandem repeats (STRs).Forensic Medicine: The application of medical knowledge to questions of law.Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.Dental Prophylaxis: Treatment for the prevention of periodontal diseases or other dental diseases by the cleaning of the teeth in the dental office using the procedures of DENTAL SCALING and DENTAL POLISHING. The treatment may include plaque detection, removal of supra- and subgingival plaque and calculus, application of caries-preventing agents, checking of restorations and prostheses and correcting overhanging margins and proximal contours of restorations, and checking for signs of food impaction.Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.Gram-Positive Cocci: Coccus-shaped bacteria that retain the crystal violet stain when treated by Gram's method.Oral Hygiene: The practice of personal hygiene of the mouth. It includes the maintenance of oral cleanliness, tissue tone, and general preservation of oral health.

Genetic polymorphism and interethnic variability of plasma paroxonase activity. (1/8027)

A method for determining plasma paroxonase activity using an auto-analyser is described. Frequency distributions for British and Indian subjects show bimodality. A study of 40 British families confirms the presence of a genetic polymorphism with regard to plasma paroxonase activity. Two phenotypes can be defined, controlled by two alleles at one autosomal locus. The frequency of the low activity phenotype is less in the Indian population than in the British population. Malay, Chinese, and African subjects fail to show obvious bimodality.  (+info)

Cephalometric abnormalities in non-obese and obese patients with obstructive sleep apnoea. (2/8027)

The aim of this work was to comprehensively evaluate the cephalometric features in Japanese patients with obstructive sleep apnoea (OSA) and to elucidate the relationship between cephalometric variables and severity of apnoea. Forty-eight cephalometric variables were measured in 37 healthy males and 114 male OSA patients, who were classed into 54 non-obese (body mass index (BMI) <27 kg x m(-2), apnoea-hypopnoea index (AHI)=25.3+/-16.1 events x h(-1)) and 60 obese (BMI > or = 27 kg x m(-2), AHI=45.6+/-28.0 events h(-1)) groups. Diagnostic polysomnography was carried out in all of the OSA patients and in 19 of the normal controls. The non-obese OSA patients showed several cephalometric defects compared with their BMI-matched normal controls: 1) decreased facial A-P distance at cranial base, maxilla and mandible levels and decreased bony pharynx width; 2) enlarged tongue and inferior shift of the tongue volume; 3) enlarged soft palate; 4) inferiorly positioned hyoid bone; and 5) decreased upper airway width at four different levels. More extensive and severe soft tissue abnormalities with a few defects in craniofacial bony structures were found in the obese OSA group. For the non-obese OSA group, the stepwise regression model on AHI was significant with two bony structure variables as determinants: anterior cranial base length (S-N) and mandibular length (Me-Go). Although the regression model retained only linear distance between anterior vertebra and hyoid bone (H-VL) as an explainable determinant for AHI in the obese OSA group, H-VL was significantly correlated with soft tissue measurements such as overall tongue area (Ton), inferior tongue area (Ton2) and pharyngeal airway length (PNS-V). In conclusion, Japanese obstructive sleep apnoea patients have a series of cephalometric abnormalities similar to those described in Caucasian patients, and that the aetiology of obstructive sleep apnoea in obese patients may be different from that in non-obese patients. In obese patients, upper airway soft tissue enlargement may play a more important role in the development of obstructive sleep apnoea, whereas in non-obese patients, bony structure discrepancies may be the dominant contributing factors for obstructive sleep apnoea.  (+info)

Laboratory assay reproducibility of serum estrogens in umbilical cord blood samples. (3/8027)

We evaluated the reproducibility of laboratory assays for umbilical cord blood estrogen levels and its implications on sample size estimation. Specifically, we examined correlation between duplicate measurements of the same blood samples and estimated the relative contribution of variability due to study subject and assay batch to the overall variation in measured hormone levels. Cord blood was collected from a total of 25 female babies (15 Caucasian and 10 Chinese-American) from full-term deliveries at two study sites between March and December 1997. Two serum aliquots per blood sample were assayed, either at the same time or 4 months apart, for estrone, total estradiol, weakly bound estradiol, and sex hormone-binding globulin (SHBG). Correlation coefficients (Pearson's r) between duplicate measurements were calculated. We also estimated the components of variance for each hormone or protein associated with variation among subjects and variation between assay batches. Pearson's correlation coefficients were >0.90 for all of the compounds except for total estradiol when all of the subjects were included. The intraclass correlation coefficient, defined as a proportion of the total variance due to between-subject variation, for estrone, total estradiol, weakly bound estradiol, and SHBG were 92, 80, 85, and 97%, respectively. The magnitude of measurement error found in this study would increase the sample size required for detecting a difference between two populations for total estradiol and SHBG by 25 and 3%, respectively.  (+info)

A case-control study of risk factors for Haemophilus influenzae type B disease in Navajo children. (4/8027)

To understand the potential risk factors and protective factors for invasive Haemophilus influenzae type b (Hib) disease, we conducted a case-control study among Navajo children less than two years of age resident on the Navajo Nation. We analyzed household interview data for 60 cases that occurred between August 1988 and February 1991, and for 116 controls matched by age, gender, and geographic location. The Hib vaccine recipients were excluded from the analyses. Conditional logistic regression models were fit to examine many variables relating to social and environmental conditions. Risk factors determined to be important were never breast fed (odds ratio [OR] = 3.55, 95% confidence interval [CI] = 1.52, 8.26), shared care with more than one child less than two years of age (OR = 2.32, 95% CI = 0.91, 5.96); wood heating (OR = 2.14, 95% CI = 0.91, 5.05); rodents in the home (OR = 8.18, 95% CI = 0.83, 80.7); and any livestock near the home (OR = 2.18, 95% CI = 0.94, 5.04).  (+info)

Relationship of plasmin generation to cardiovascular disease risk factors in elderly men and women. (5/8027)

Plasmin-alpha2-antiplasmin complex (PAP) marks plasmin generation and fibrinolytic balance. We recently observed that elevated levels of PAP predict acute myocardial infarction in the elderly, yet little is known about the correlates of PAP. We measured PAP in 800 elderly subjects who were free of clinical cardiovascular disease in 2 cohort studies: the Cardiovascular Health Study and the Honolulu Heart Program. Median PAP levels did not differ between the Cardiovascular Health Study (6.05+/-1.46 nmol/L) and the Honolulu Heart Program (6.11+/-1.44 nmol/L), and correlates of PAP were similar in both cohorts. In CHS, PAP levels increased with age (r=0. 30), procoagulant factors (eg, factor VIIc, r=0.15), thrombin activity (prothrombin fragment F1+2, r=0.29), and inflammation-sensitive proteins (eg, fibrinogen, r=0.44; factor VIIIc, r=0.37). PAP was associated with increased atherosclerosis as measured by the ankle-arm index (AAI) (P for trend, +info)

Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. The Insulin Resistance Atherosclerosis Study (IRAS). (6/8027)

Hyperinsulinemia is associated with the development of coronary heart disease. However, the underlying mechanisms are still poorly understood. Hypercoagulability and impaired fibrinolysis are possible candidates linking hyperinsulinism with atherosclerotic disease, and it has been suggested that proinsulin rather than insulin is the crucial pathophysiological agent. The aim of this study was to investigate the relationship of insulin and its precursors to markers of coagulation and fibrinolysis in a large triethnic population. A strong and independent relationship between plasminogen activator inhibitor-1 (PAI-1) antigen and insulin and its precursors (proinsulin, 32-33 split proinsulin) was found consistently across varying states of glucose tolerance (PAI-1 versus fasting insulin [proinsulin], r=0.38 [r=0.34] in normal glucose tolerance; r=0.42 [r=0.43] in impaired glucose tolerance; and r=0.38 [r=0.26] in type 2 diabetes; all P<0.001). The relationship remained highly significant even after accounting for insulin sensitivity as measured by a frequently sampled intravenous glucose tolerance test. In a stepwise multiple regression model after adjusting for age, sex, ethnicity, and clinic, both insulin and its precursors were significantly associated with PAI-1 levels. The relationship between fibrinogen and insulin and its precursors was significant in the overall population (r=0.20 for insulin and proinsulin; each P<0.001) but showed a more inconsistent pattern in subgroup analysis and after adjustments for demographic and metabolic variables. Stepwise multiple regression analysis showed that proinsulin (split products) but not fasting insulin significantly contributed to fibrinogen levels after adjustment for age, sex, clinic, and ethnicity. Decreased insulin sensitivity was independently associated with higher PAI-1 and fibrinogen levels. In summary, we were able to demonstrate an independent relationship of 2 crucial factors of hemostasis, fibrinogen and PAI-1, to insulin and its precursors. These findings may have important clinical implications in the risk assessment and prevention of macrovascular disease, not only in patients with overt diabetes but also in nondiabetic subjects who are hyperinsulinemic.  (+info)

Low-density lipoprotein particle size is inversely related to plasminogen activator inhibitor-1 levels. The Insulin Resistance Atherosclerosis Study. (7/8027)

High levels of plasminogen activator inhibitor-1 (PAI-1) and preponderance of small dense low-density lipoproteins (LDL) have both been associated with atherosclerotic disease and with the insulin resistance syndrome (IRS). In vitro studies have shown a stimulatory effect of various lipoproteins on PAI-1 release from different cells, including endothelial cells and adipocytes. The authors sought to investigate the relation of PAI-1 to LDL particle size in a large tri-ethnic population (n=1549) across different states of glucose tolerance. LDL size was determined by gradient gel electrophoresis, and PAI-1 was measured by a 2-site immunoassay, sensitive to free PAI-1. PAI-1 was inversely related to LDL size in the overall population (r=-0.21, P<0.0001), independent of gender and ethnicity. However, the authors found a significant interaction with glucose tolerance status (P=0.035). In univariate analysis, the association between PAI-1 and LDL size was most pronounced in subjects with normal glucose tolerance (NGT, r=-0.22, P<0.0001) and weaker in impaired glucose tolerance (IGT, r=-0.12, P=0.03) and type-2 diabetes (r=-0.10, P=0.02). After adjustment for demographic variables and metabolic variables known to influence PAI-1 levels (triglyceride and insulin sensitivity), a significant inverse relation of LDL size to PAI-1 levels was only present in NGT (P=0. 023). In subjects with IGT or overt diabetes, who usually have elevated PAI-1 levels, additional factors other than LDL size seem to contribute more importantly to PAI-1 levels. The demonstrated inverse relation of LDL size and PAI-1 levels provides one possible explanation for the atherogeneity of small dense LDL particles.  (+info)

Influence of ethnic background on clinical and serologic features in patients with systemic sclerosis and anti-DNA topoisomerase I antibody. (8/8027)

OBJECTIVE: To investigate the effect of ethnicity on clinical and serologic expression in patients with systemic sclerosis (SSc) and anti-DNA topoisomerase I (anti-topo I) antibody. METHODS: Clinical and serologic features, as well as HLA class II allele frequencies, were compared among 47 North American white, 15 North American black, 43 Japanese, and 12 Choctaw Native American SSc patients with anti-topo I antibody. RESULTS: The frequency of progressive pulmonary interstitial fibrosis was lower, and cumulative survival rates were better in white compared with black and Japanese patients. Sera of white and black patients frequently recognized the portion adjacent to the carboxyl terminus of topo I, sera of Japanese patients preferentially recognized the portion adjacent to the amino terminus of topo I, and sera of Choctaw patients recognized both portions of topo I. Anti-RNA polymerase II and anti-SSA/Ro antibodies were present together with anti-topo I antibody more frequently in sera of Japanese patients than in sera of white patients. The HLA-DRB1 alleles associated with anti-topo I antibody differed; i.e., DRB1*1101-*1104 in whites and blacks, DRB1*1502 in Japanese, and DRB1*1602 in Choctaws. Multivariate analysis showed that ethnic background was an independent determinant affecting development of severe lung disease as well as survival. CONCLUSION: Clinical and serologic features in SSc patients were strongly influenced by ethnic background. The variability of disease expression in the 4 ethnic groups suggests that multiple factors linked to ethnicity, including genetic and environmental factors, modulate clinical manifestations, disease course, and autoantibody status in SSc.  (+info)

*List of MeSH codes (M01)

... asian americans MeSH M01.686.508.400 --- european continental ancestry group MeSH M01.686.508.600 --- oceanic ancestry group ... continental population groups MeSH M01.686.508.100 --- african continental ancestry group MeSH M01.686.508.100.100 --- african ... asian continental ancestry group MeSH M01.686.508.200.100 --- ... american native continental ancestry group MeSH M01.686.508.150 ... asian americans MeSH M01.686.754.283 --- gypsies MeSH M01.686.754.441 --- Hispanic Americans MeSH M01.686.754.441.500 --- ...

*Race, Evolution, and Behavior

... terms have since been replaced in the scientific literature-the MeSH terminology as of 2004 is Asian Continental Ancestry Group ... African Continental Ancestry Group and European Continental Ancestry Group.) Rushton uses averages of hundreds of studies, ... in favor of terms such as African Continental Ancestry Group: The MeSH descriptor Racial Stocks, and its four children ( ... Recent genetic research indicates that the degree of genetic heterogeneity within groups and homogeneity across groups make ...

*Asian people

November 17, 2006.Nlm.nih.gov: Asian Continental Ancestry Group is also used for categorical purposes. British Sociological ... "Asian". Afro-Asian (African-Asian mixed ancestry) Amerasian - especially the offspring of a U.S. serviceman and an Asian Asia ... "West Asian", "South Asian", "Central Asian" and "Southeast Asian". The Canadian government uses "West Asian" in its statistics ... combining several individual ancestry groups into "Asian or Pacific Islander." By the 1990 Census, Asian or Pacific Islander ( ...

*Asian Canadians

Canadians of Asian ancestry comprise the largest and fastest growing visible minority group in Canada, with roughly 17% of the ... In Canada, the term 'Asian' is pan-continental unlike its usage in the US and Australia. See Asian Americans. Asian Canadians ... of Canadians of Asian ancestry South Asian Canadians Asian Americans Asian Argentines Asian Australians Asian Brazilians Asian ... Asian Canadians refers to Canadians who can trace their ancestry back to the continent of Asia or Asian people. ...

*Human genetic variation

... many individuals affiliate with two or more continental groups. Thus, the genetically based "biogeographical ancestry" assigned ... Western Asians, Central Asians, Southern Asians and Northern Africans; Eastern Asians, Southeast Asians, Polynesians and Native ... of the variation in human head shapes occurs within continental groups, and ~10% separates groups, with a greater variability ... Forensic anthropologists can determine aspects of geographic ancestry (i.e. Asian, African, or European) from skeletal remains ...

*Y Chromosome Haplotype Reference Database

... criterion seems most appropriate to group data by taking the ancestry into account and produce subdatabases with respect to ... Continental Metapopulations in the YHRD comprises all individuals sampled in a particular continent regardless of their ... East Asian, Eskimo-Aleut, and Eurasian. Some of these metapopulations are further subdivided, e.g. Eurasian into six ... Thus, the population groups are more similar within the metapopulation than to groups outside the metapopulation. The concept ...

*Race and intelligence

When one samples continental groups, the clusters become continental; if one had chosen other sampling patterns, the clusters ... is a visual estimate of a person's continental ancestry based on their phenotype-which correlates with genotypical ancestry as ... They found the highest national IQs among Western and East Asian developed nations and the lowest national IQs in the world's ... Hence the causes of differences within a group and between groups may not be the same, even when looking at traits that are ...

*Human genetic clustering

When one samples continental groups the clusters become continental; if one had chosen other sampling patterns the clustering ... Pan-Asian SNP Consortium in 2009 using the similar principal components analysis found that East Asian and South-East Asian ... the genetic ancestry test is using the HapMap reference population is likely to incorrectly assign the ancestry of that portion ... between individuals within continental groups relative to genetic differences between individuals between continental groups. ...

*Chinese Americans

The Chinese American community comprises the largest ethnic group of Asian Americans, comprising 25.9% of the Asian American ... as well as East Asian or East Asian American subjects of Vietnamese, Korean, Filipino and Chinese ancestry. A clear ... The continental populations are from the Human Genome Diversity Panel (Cambodian, Yi, Daur, Mongolian, Lahu, Dai, Hezhen, ... Chinese Americans constitute one group of overseas Chinese and also a subgroup of East Asian Americans, which is a further ...

*Race and genetics

When one samples continental groups, the clusters become continental; with other sampling patterns, the clusters would be ... groups based on phenotypical traits and impressions of probable geographic ancestry and cultural identity-these are the groups ... African and East Asian). The global human population is more complex, and studying a large number of groups would require an ... and self-identified race or ethnic groups does not mean that such a cluster (or group) corresponds to only one ethnic group. ...

*Multiregional origin of modern humans

Garrigan, D.; Mobasher, Z.; Severson, T.; Wilder, J. A.; Hammer, M. F. (February 2005). "Evidence for archaic Asian ancestry on ... A second group finds the same ancient origin for PDHA1, but finds no evidence of a recent expansion, consistent with other ... Theory proponents also explain this with the fact that genetic changes occur on a regional basis rather than a continental ... the ancestry from these archaic alleles at the HLA-A site was more than 50% for modern Europeans, 70% for Asians, and 95% for ...

*Breinigsville, Pennsylvania

Of the population 7.08% were of Hispanic or Latino ancestry. The town has a population of 4,138 with a median age of 34.6. The ... In 2012, TEK Park was sold to MRA Group for $50 million. As of the 2010 census, Breinigsville consists of 51.11% females and ... Breinigsville lies within the humid continental climate zone (Köppen: Dfa ), and experiences four distinct seasons. Summers are ... Asian, 0.0% Native Hawaiian, 1.55% were two or more races, and 1.74% were some other race. ...

*Cumans

A group of families formed a clan, led by a chief; a group of clans formed a tribe, led by a khan. A typical Cuman clan was ... Nevertheless, the Asian mitochondrial haplotype in sample Cu26 may still reflect the Asian origins of the Cumanians of Csengele ... It is interesting that the only skeleton for which anthropological examination indicated a partly European ancestry was that of ... although haplogroup F is almost absent in continental Europe; therefore the presence of this haplogroup in the modern Hungarian ...

*Kunság

Haplogroups U3 and D occur exclusively in the ancient group, and 11 haplogroups (HV, U4, U5, K, J, J1a, T, T1, T2, W, and F) ... All but one is a West Eurasian haplogroup [the remaining one is East Asian (haplogroup F)], but all belong to the N lineage. ... It is interesting that the only skeleton for which anthropological examination indicated a partly European ancestry was that of ... although haplogroup F is almost absent in continental Europe; therefore the presence of this haplogroup in the modern Hungarian ...

*Antonio Arnaiz-Villena

Greeks possess none of the lineages denoting North African ancestry within the last 5000 years and have only 2% (3/148) of the ... In a sample of 125 Greeks from Thessaloniki and Sarakatsani, 2 Asian-specific mtDNA sequences (M and D) were detected (1.6%). ... Antonio Arnaiz-Villena is a Spanish immunologist noted for his controversial research into the genetic history of ethnic groups ... Additionally, in a sample of 366 Greeks from thirteen locations in continental Greece, Crete, Lesvos and Chios, a single ...

*Caspian, Michigan

Mlive Media Group. December 4, 2016. Retrieved December 5, 2016. Walter Romig, Michigan Place Names, p. 102. "Census of ... 26.6% were of Italian, 13.8% German, 10.9% Polish, 9.2% Finnish, 8.4% Swedish and 6.4% French ancestry according to Census 2000 ... According to the Köppen Climate Classification system, Caspian has a humid continental climate, abbreviated "Dfb" on climate ... Asian, 0.20% from other races, and 0.50% from two or more races. Hispanic or Latino of any race were 0.30% of the population. ...

*Demographics of Chicago

The racial makeup of the city in 2010 was 45.3% white (31.7% non-Hispanic white), 32% black, 5% Asian, and 3% from two or more ... One of the most distinct of these German groups were the Volga Germans, or ethnic Germans having lived along the Volga River in ... As of the 2010 Census, Chicago has the third-largest Puerto Rican population in the continental United States, after New York ... As of the 2007 US Census American Community Survey the largest European ancestries were: Irish: (201,836) German: (200,392) ...

*Huancayo

Amerindian and Mestizos (Amerindian and Spanish ancestry) are the two largest ethnic groups in the city. Asian (mainly ... Universidad Nacional del Centro del Peru (UNCP) Universidad Peruana Los Andes (UPLA) Universidad Continental de Ciencias e ... descendants of Japanese and Chinese immigrants) and European descendants are important minority groups. Huancayo has ...

*Demographics of Filipino Americans

More than half of Asian Americans in Nevada in 2010 were Filipino, and are the largest group of Asian Americans in Nevada. In ... By the early 2010s estimates were there were around 90,000 Filipinos living in the region, being the largest Asian-ancestry in ... the San Francisco-Oakland metropolitan area had the largest population of Filipinos of any metropolitan area in the continental ... ISBN 978-0-7385-7134-8. Wu, Sen-Yuan (17 February 2012). "New Jersey's Asian Population by Asian Group: 2010" (PDF). NJ ...

*Racial segregation

These minority groups have long tenured residence in the Republic, but are precluded from becoming citizens as a result of ... Segregation continues today, but more than 35%of the fishermen in the BC commercial fishery are of aboriginal ancestry, yet ... PHILLIPS, D. (2002) Movement to opportunity? South Asian relocation in northern cities. End of Award report, ESRC R000238038. ... Indians and other Sub-Continentals, and has been thought to be the basis of ethnic tensions, and a deterioration of the ...

*Juniata County, Pennsylvania

The same rock formations are found in the borough of Port Royal, along with the Clinton Group and the Hamilton Group to the ... Juniata County is in the Humid Continental climatic region. In the summer, highs are generally in between 80 °F (27 °C) and 90 ... Asian (0.1% Indian, 0.1% Chinese, and 0.1% Korean), 1.1% from other races, and 1% from two or more races. There are eight ... English ancestry according to Census 2000. 3.95% reported speaking Pennsylvania German, German, or Dutch at home; 1.63% speak ...

*Rochester, Minnesota

In terms of ancestry, the 2005-2007 American Community Survey found German Americans to be the largest single ethnic group in ... Rochester features a humid continental climate (Dfa/Dfb), with hot summers and very cold winters. The city features four ... Asian (1.3% Indian, 1.2% Cambodian, 1.0% Chinese, 0.9% Vietnamese, 0.6% Laotian, 0.4% Korean, 0.4% Filipino, 0.2% Hmong, 0.1% ... In addition, Kerry Flavours and Ingredients, a subsidiary of the global Irish company called Kerry Group, maintains a ...

*Mexicans of European descent

Other ethnic group in Mexico, the Mestizos, is characterized by having people with varying amounts of European ancestry, with ... "Asian" (primarily Amerindian), and 5.03% Other. An autosomal ancestry study performed on Mexico city reported that the European ... among other statistics the relatively low frequency of marriages between people of different continental ancestries in colonial ... counting only studies that looked at the ancestry of both parents (autosomal ancestry): "Amerindian ancestry is most prevalent ...

*Plymouth, Minnesota

On May 11, 1858, the group voted to change the town's name to Medicine Lake. This was used once at the town meeting, but for ... 27.0% were of German, 13.1% Norwegian, 7.8% Irish and 7.5% Swedish ancestry. There were 24,820 households out of which 37.8% ... Plymouth has a humid continental climate, typical of the Midwestern United States, with very cold winters, and hot, often humid ... Asian, 1.0% from other races, and 2.3% from two or more races. Hispanic or Latino of any race were 3.0% of the population. ...

*Australasia

... is separated by deep water from both the southeast Asian continental shelf and the Australia-New Guinea continental shelf. ... A group of Australasian islands east of the Wallace Line, including Sulawesi, Halmahera, Lombok, Flores, Sumba, Sumbawa, and ... others specific to particular parts but sharing a common ancestry. The long isolation of Australasia from other continents ... Similarly, Australia and New Guinea are linked by a shallow continental shelf, and were linked by a land bridge during the ice ...

*Iron Mountain, Michigan

Both formations belong to the Animikie Group. The Vulcan is between 300 and 800 feet thick and consists of hematite and ... 20.6% were of Italian, 14.0% German, 9.0% Swedish, 8.8% English, 8.8% French, 5.8% Finnish and 5.5% Irish ancestry according to ... According to the Köppen Climate Classification system, Iron Mountain has a humid continental climate, abbreviated "Dfb" on ... Asian, 0.3% from other races, and 1.7% from two or more races. Hispanic or Latino of any race were 1.6% of the population. ...
The 9p21 locus, a strong risk locus for coronary arterial disease, has been also associated with other cardiovascular disease including ischemic stroke (IS) in Caucasians. However, the association between 9p21 locus and IS in Chinese Han population is still debatable because of ambiguous results reported previously. Genetic heterogeneity between Southern and Northern Chinese Han populations could be one of the reasons for this uncertainty. Four genetic variants selected from the three conjunctional LD blocks within the 44 kb candidate region on chromosome 9p21 were genotyped in 1,429 IS patients and 1,191 healthy controls from the Northern Chinese Han population. Among the four studied variants, the G allele of the SNP rs2383207 was significantly associated with IS with allele frequency 66.8% in patients and 63.4% in controls. This association appears to be dominant with an OR of 1.417 (p=0.003) for people with either GG or AG genotypes. We did not find any association for the other three SNPs
This study suggests that the APOB polymorphism rs679899 is associated with type 2 diabetes and GGT levels, while the LIPC polymorphism rs6083 may influence CHOL, TG, and LDL levels in Chinese Han population.
Loci with genome-wide associations with schizophrenia in the Han Chinese population - Volume 207 Issue 6 - Zhiqiang Li, Yuqian Xiang, Jianhua Chen, Qiaoli Li, Jiawei Shen, Yun Liu, Wenjin Li, Qinghe Xing, Qingzhong Wang, Lei Wang, Guoyin Feng, Lin He, Xinzhi Zhao, Yongyong Shi
The JAK2-STAT3 pathway is a signaling target of a multitude of cytokines that are thought to play significant biological roles in immune-mediated diseases. This pathway is essential in Th1 cell differentiation and proliferation. Additionally, it is also important for the development of Th17 cells. 12 Both Th1 and Th17 cells play critical roles in immune-mediated diseases such as BD. 26 The JAK2 and STAT3 signaling pathway may thus exert its influence on immune-mediated diseases, including BD, by modulating the Th1 and Th17 response. Recently, genetics polymorphisms of JAK2 and STAT3 have been investigated for their association with a number of autoimmune diseases including Crohns disease and ulcerative colitis. 20,27 -32 All these results prompted us to examine whether the polymorphisms of the JAK2 and STAT3 genes could possibly also contribute to the development of BD in a Han Chinese population. To ensure the results, we made the following efforts. First, we strictly selected the patients ...
Sigma-Aldrich offers abstracts and full-text articles by [Xingwang Li, Jing Zhang, Yang Wang, Jue Ji, Fengping Yang, Chunling Wan, Peng Wang, Guoyin Feng, Klaus Lindpaintner, Lin He, Guang He].
Objective: Our objective was to compare total body fat to lean mass ratio (F:LM) in Aboriginal, Chinese, European, and South Asian individuals with differences in insulin resistance.. …. Results: After adjustment for confounders and at a given body fat, South Asian men had less lean mass than Aboriginal [3.42 kg less; 95% confidence interval (CI) = 1.55-5.29], Chinese (3.01 kg less; 95% CI = 1.33-4.70), and European (3.57 kg less; 95% CI = 1.82-5.33) men, whereas South Asian women had less lean mass than Aboriginal (1.98 kg less; 95% CI = 0.45-3.50), Chinese (2.24 kg less; 95% CI = 0.81-3.68), and European (2.97 kg less; 95% CI = 1.67-4.27) women. In adjusted models, F:LM was higher in South Asian compared with Chinese and European men and higher in South Asian compared with Aboriginal, Chinese, and European women (P < 0.01 for all). Insulin and HOMA were greatest in South Asians after adjustment; however, these differences were no longer apparent when F:LM was considered.. Conclusions: South ...
This study investigated bioavailability of pegvisomant single 30 mg/ml subcutaneous injection versus two 15 mg/ml subcutaneous injection in healthy Asian
Heart attacks strike South Asian men and women at younger ages and are more deadly compared to people from other world regions. [...] last month, Stanford Health Care opened the Stanford South Asian Translational Heart Initiative, a program that will treat existing heart patients, screen potential ones and conduct research. Dr. Rajesh Dash, medical and scientific director for the Stanford initiative, explained that genetics seem to put South Asians in harms way, even when their cholesterol and blood glucose levels and body mass index measurements are just a little elevated. 4 times South Asians risk of heart disease is four times greater than the general world populations, according to statistics provided by the South Asian Heart Center at El Camino Hospital.
A mongoloid baby is crying on the subway and so now everyone is a hostage. Everyone is either sitting next to or across from the baby or standing up and away from it but we might as well be bound and gagged in the back of a gas station. We all look at each other like we dont know what but its undeniable and true that we want this baby dead or to stop crying so we can go back to the magazine we are reading or the music we are listening to or the frayed hem of the skirt we cant stop touching. Everyone feels badly about this, about wanting this baby dead or to stop crying because it is a Mongoloid baby and it is the middle of the day. Perhaps if it were early morning or late at night people would feel differently and yes, its true, that everyone knows youre not supposed to call this kind of baby a Mongoloid anymore, but this is what we call him. Maybe if this baby werent a Mongoloid everyone would feel differently, but theres no way of knowing. We think most people dont want to be around a ...
The reason why, the researchers said, is because their bodies store extra fat differently. Rather than distributing it throughout the body under the skin, as is the case with people from most ethnic groups, the bodies of individuals of South Asian descent store the fat around the internal organs of the abdomen. This is known as visceral fat ...
Evolutionary biologists call it the r-K scale of reproductive strategies. At one end of this scale are r-strategies that rely on high reproductive rates. At the other end are K-strategies that rely on high levels of parental care. This scale is generally used to compare the life histories of different species of animals. I have used it to explain the smaller but real differences between the human races.. On this scale, Orientals are more K-selected than Whites, while Whites are more K-selected than Blacks. Highly K-selected women produce fewer eggs (and have bigger brains) than r-selected women. Highly K-selected men invest time and energy in their children rather than the pursuit of sexual thrills. They are "dads" rather than "cads.". Chapter 7 shows that the race differences in reproductive strategies make sense in terms of human evolution. Modern humans evolved in Africa about 200,000 years ago. Africans and non-Africans then split about 100,000 years ago. Orientals and Whites split about ...
rs2024513 is a SNP in the neurexin-1 NRXN1 gene on chromosome 2p16.3. Based on a case-control study of 700+ Han Chinese patients with schizophrenia, rs2024513(A) was associated with higher risk, at an odds ratio of 1.3 (CI: 1.07 - 1.56, p=0.006).[PMID 21477380 ...
Quote: Originally Posted by Looking for a fight You seem a multiculturalist speaking. The speaking of the facts that we have today...
A condition which, as its name suggests, is most common among people of Asian descent, although it can be found to a lesser extent in individuals from ...
Vol 8: Association between IL-21 gene rs907715 polymorphisms and Graves- disease in a Southern Chinese population.. This article is from Experimental and Therapeutic Medicine, volume 8.AbstractInterleukin-21 (IL-21) is a pleiotropic cyt. Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
TY - JOUR. T1 - Allelic diversity and haplotype structure of HLA loci in the Chinese Han population living in the Guanzhong region of the Shaanxi province. AU - Shen, Chun Mei. AU - Zhu, Bo Feng. AU - Ye, Shi Hui. AU - Liu, Meng Li. AU - Yang, Guang. AU - Liu, Sheng. AU - Qin, Hai Xia. AU - Zhang, Hua Dong. AU - Lucas, Rudolf. AU - Li, Shen Bing. PY - 2010/6/1. Y1 - 2010/6/1. N2 - The allele and haplotype frequencies of HLA-A, -B and -DRB1 loci in 10,000 healthy unrelated Han individuals living in the Guanzhong region of the Shaanxi Province were analyzed with the methods of SSO, SSP and SBT. Subsequently, these data were compared with results obtained in Han populations living in other regions as well as to other ethnic groups, using genetic distance measurements, neighbor-joining dendrograms and principal component analysis. In total 18 alleles were detected at the HLA-A locus, 46 alleles at the HLA-B locus and 14 alleles at the HLA-DRB1 locus. HLA-A02 was the most common HLA-A allele ...
Aims: To describe the prevalence and causes of decreased visual acuity (VA) in Singaporean Chinese children. Methods: A population-based survey of Singaporean Chinese children aged 6 to 72 months was conducted. Participants underwent an orthoptic evaluation, cycloplegic refraction and biometric measurements. A sub-group of children aged 30 to 72 months with presenting logMAR VA were included in this analysis. Retesting was performed on the same day or another day by predefined criteria with best refractive correction. Decreased VA was defined as worse than 20/50 (0.4 logMAR) for ages 30 to 47 months and worse than 20/40 (0.3 logMAR) for ages 48 to 72 months. Results: The study examined 3009 children (participation rate 72.3%) of which 2017 children aged 30 to 72 months were eligible for VA testing and completed in 1684 (83.5%). In children aged 30-47 months, the prevalence of decreased presenting VA was 2.1%, and in children 48-72 months, it was 2.05%, with no significant difference between boys ...
The present study was performed to investigate the association of IL23R polymorphisms with Fuchs syndrome in a Chinese Han population. The results showed that the AA genotype of the rs11209032 SNP was associated with an increased susceptibility to Fuchs syndrome. However, there was no difference with regard to the genotypes and alleles of rs7517847 and rs17375018 between patients with Fuchs syndrome and normal controls. Fuchs syndrome is a relatively rare uveitis entity [2]. Although the etiology and pathogenesis of Fuchs syndrome are not fully understood, several hypotheses including sympathetic lesions, association with ocular toxoplasmosis, vascular abnormalities, viral infections and autoimmunity have been proposed [15,16]. Among these presumptions, a viral infection has been accepted, as supported by the demonstration of local intraocular antiviral antibody production [16-18],Elevatedγ-interferon and interleukin 10, an increased number of CD8+ T cells in the aqueous humor and a ...
For this study, 461 Chinese Han patients with depressive disorder were recruited. The AKT1 genotype and allele distribution were determined by PCR amplification and direct sequencing. UNPHASED software was used to analyze associations between the 17-item Hamilton Depression Rating Scale, total score, four factors and the AKT1 rs2494746 and rs3001371 polymorphisms. The results indicate that there is a significant association between suicidal ideation and anxiety symptoms in depressed patients and the rs2494746 polymorphism. The other AKT1 polymorphism, rs3001371, was significantly associated with work and activities. Patients with the rs3001371-A allele had a significantly more severe illness compared to patients with the rs3001371-G allele. Thus, AKT1 polymorphisms appear to be associated with depression severity, anxiety symptoms, work and activities, and suicide attempts in patients with depressive disorder.
In a prospective study of a general Japanese population, we clearly demonstrated that elevated HbA1c levels, even in the prediabetic range, were a significant risk factor for the development of CVD, especially for CHD and ischaemic stroke, in a general Japanese population. These associations remained robust even after controlling for comprehensive confounding factors. Furthermore, adding the HbA1c value to the confounding factors significantly improved the predictive ability for total CVD. These findings are important in that they indicate HbA1cs value for predicting the long-term risk of CVD in Japanese.. Some clinical and population-based cohort studies have shown that increased HbA1c levels were positively associated with the risks of CVDs and mortality [6-11, 20-25]. In the present study, the risks of CHD and ischaemic stroke were significantly or marginally higher even in the subjects with HbA1c levels of ≥5.5% compared with those with HbA1c levels of ≤5.0%. There has been controversy ...
GSK2190915 is currently in development for the treatment of asthma. This study aims to assess the safety and tolerability of single doses of GSK2190915 in healthy Japanese subjects. The study will also look at the pharmacokinetics (PK) and pharmacodynamics (PD) of single doses of GSK2190915 and aims to characterise the PK/PD relationship in healthy Japanese subjects. Twelve healthy Japanese subjects will take part in this single escalating dose study and subjects will receive one of five possible treatments, 10 mg, 50 mg, 150 mg, 450 mg GSK2190915 or placebo in each treatment period. Blood samples (for safety, pharmacokinetics and pharmacodynamics), urine samples (for safety and pharmacodynamics) and ECGs, blood pressure readings, physical examinations and a review of adverse events will take place at a number of timepoints pre and post each dose. A minimum 7 day washout between treatment periods will be required. Regardless if a subject completes or prematurely withdraws from the study, a ...
The principal function of NILTs is to identify patients with high probability of having advanced fibrosis at the time of testing. Currently, decisions such as management in primary or secondary care or consideration for clinical trials are largely based on the results of these NILTs. As with any clinical test, there is a danger that if applied or interpreted inappropriately, wrong decisions can be made and, ultimately, harm may come to a patient. Despite the relatively small sample size, our data show that the sensitivity of commonly used NILTs is lower in patients of South Asian ethnicity suggesting that large numbers of South Asian patients may be inappropriately reassured that they do not have advanced disease. We recorded self-reported ethnicity and not first or subsequent generation immigration. Nevertheless, our data suggest that NASH may be more aggressive in South Asian patients who are almost a decade younger, have lower BMI and less severe BMI category than white patients with ...
Background Telomerase expression is one of the characteristics of gastric cancer (GC) cells and telomerase activity is frequently up-regulated by a variety of mechanisms during GC development....
PK samples at pre-dose, 0.25h, 0.5h, 0.75h, 1h, 1.5h, 2h, 2.5h, 3h, 4h, 5h, 6h, 8h, 10h, 12h, 16h and 24h, 36h, 48h, 72h, 96h, 120h, 144h and 168h post dose after single dose and at the time points pre-dose, 0.25h, 0.5h, 0.75h, 1h, 1.5h, 2h, 2.5h, 3h, 4h, 5h, 6h, 8h, 10h, 12h, 16h and 24h after administration of a repeated ...
Chinese peoples joints wear out too, but replacement implants have, on occasion, been too large. Now a team of 21 experts from France and Chinas Sichuan
List of causes of Mongoloid palpebral fissure in children and Respiratory symptoms, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
With increasing number of epidemiological studies about BLL in China in recent years, it is now possible to obtain direct evidence of lead poisoning situation of Chinese population aged 0-18 years old. Based on strict inclusion criteria, eliminated relative low-quality studies by quality assessment of cross-sectional study, we identified 55 articles in this meta-analysis including 200,002 subjects, covering 19 provinces, autonomous regions and municipalities, thus the large population guaranteed the reliability of this study.. In this study, pooled rate of BLL ≥10 μg/dL in the 0-18 year old Chinese population during 1990-2012 was 25.1 % and corrected pooled rate under trim and fill method was 9 %, both much higher than all levels during 1991-1994 (4.4 %), 1999-2002 (1.6 %) and 2007-2010 (0.8 %) in US [8-10].. Considering high heterogeneity, subgroup analysis of different study year ranges showed overall decreasing trend of the rate with time. The decline appears to be attributed to government ...
THE EARTH A SPHERE. -- That the earth, too, is round is shown thus. The signs and stars do not rise and set the same for all men everywhere but rise and set sooner for those in the east than for those in the west; and of this there is no other cause than the bulge of the earth. Moreover, celestial phenomena evidence that they rise sooner for Orientals than for westerners. For one and the same eclipse of the moon which appears to us in the first hour of the night appears to Orientals about the third hour of the night, which proves that they had night and sunset before we did, of which setting the bulge of the earth is the cause ...
PMID 23838578] Genetic variants rs2393903 at 10q21.2 and rs6010620 at 20q13.33 are associated with clinical features of atopic dermatitis in the Chinese Han population ...
This phase 1 study investigated Pharmacokinetics of apatinib in healthy Caucasian, Japanese and Chinese subjects following a single-dose administration to
Describes the nature and extent of residential provision for people with intellectual disabilities in 1991 in England, Scotland and Wales. Data from the OPCS Census suggest that: (1) substantial regional and national variation existed; (2) overall, the level of provision was significantly lower than Department of Health targets for 1991; (3) the majority of people with intellectual disabilities were living in relatively large-scale congregate care settings; (4) the majority of residents were younger and middle-aged adults; (5) young black men were significantly more likely to be placed in residential provision than their peers from other ethnic groups; (6) young Asian men, young Chinese/Other men and young Asian women were significantly less likely to be placed in residential provision than their peers from other ethnic groups; (7) rates of employment and marriage among residents were markedly lower than for the general population. The results are discussed in relation to national policy aims ...
Chinaman isnt racist - just unfashionable. Just like Oriental. After all, Chinese are from China, which is in the Orient. Its not like moron and idiot, which started out just like Chinaman, i.e. once upon a time they were literally, the word for that. The only reason idiot & moron became insults/slurs is because of everyone metaphorically comparing each other to idiots. But the thing is, people are always gonna want to call out stupid people, so the name for retarded or whatnot has to change every few years to keep one step ahead of people trying to use it to fuck with each other. Pretty sure retarded isnt the right word anymore either, and I dont even know the current term, but whoever decides these things should pick something so boring and bureaucratic/totalitarian-sounding that nobody even wants to use it as a slur - like differently abled - that was a good one. Whereas nobody is looking to call their non-Chinese friends Chinese, or call attention to Chinese people. Youre ...
Chinaman isnt racist - just unfashionable. Just like Oriental. After all, Chinese are from China, which is in the Orient. Its not like moron and idiot, which started out just like Chinaman, i.e. once upon a time they were literally, the word for that. The only reason idiot & moron became insults/slurs is because of everyone metaphorically comparing each other to idiots. But the thing is, people are always gonna want to call out stupid people, so the name for retarded or whatnot has to change every few years to keep one step ahead of people trying to use it to fuck with each other. Pretty sure retarded isnt the right word anymore either, and I dont even know the current term, but whoever decides these things should pick something so boring and bureaucratic/totalitarian-sounding that nobody even wants to use it as a slur - like differently abled - that was a good one. Whereas nobody is looking to call their non-Chinese friends Chinese, or call attention to Chinese people. Youre ...
The Chinese Exclusion Act (1882) was a US law that shut off all immigration of the Chinese race to the US - except for scholars, merchants, diplomats and professionals. Chinese people already in the US had to carry ID, even citizens. It is where the American idea of illegal aliens comes from, the beginning of…
Analysis of ERBB4 mutations and expression in japanese patients with lung cancer.: Only the kinase domain of ERBB4 has been analyzed in East Asian populations,
... This is a group for Chinese Adults to view and post photos, leave messages and arrange for other fun and adventures. Please add your two cents. yahoo.com/group/Indian-Adults yahoo.com/group/Pakistani-AdultsAsian Personals
Consistent with previous descriptions, our results show that the African population is the most diverse in terms of the number of variants expected to exist, the Asian populations the least diverse, with the European population in-between. In addition, our results show a clear distinction between the Chinese and the Japanese populations, with the Japanese population being the less diverse. To find all common variants (frequency at least 1%) the number of individuals that need to be sequenced is small (∼350) and does not differ much among the different populations; our data show that, subject to sequence accuracy, the 1000 Genomes Project is likely to find most of these common variants and a high proportion of the rarer ones (frequency between 0.1 and 1%). The data reveal a rule of diminishing returns: a small number of individuals (∼150) is sufficient to identify 80% of variants with a frequency of at least 0.1%, while a much larger number (> 3,000 individuals) is necessary to find all of ...
Libraries, Committee on East Asian (1981) "Notice on Membership," Journal of East Asian Libraries: Vol. 1981 : No. 66 , Article 11 ...
Google is continuing to test new strategies in China after the U.S. search giant released its first mini program for WeChat, the countrys hugely popular messaging app. WeChat is used by hundreds of millions of Chinese people daily for services that stretch beyond chat to include mobile payments, bill paying, food delivery and more. Tencent, […]
Indian American Rajeev Majumdar sworn in as Washington State Bar Associations new president-- the first state bar president of South Asian descent.
A photo of a Chinese woman, Feng Jianmei, and the bloody body of her 7-month-old fetus has outraged web users in China. Feng was forced to have an abortion
Researchers found that a gene mutation prevents tyrosine kinase inhibitors from working in some East Asian cancer patients, and can correct this.
At first glance, things seem to be getting better for Japanese women. In an economy thats historically lagged other developed nations when it comes to fem
Zhongli Quan or Han Zhongli, one of the Eight Immotrals One of the Eight Immortals in Chinese folklore is Han Zhongli or Zhongli Quan. Here is a slightly different account of his birth and his life. Han Zhongli means a man named Zhongli of the Han dynasty (206 B.C. - 220 A.D.). The name Zhongli…
As of Jan. 1, number of Japanese people fell by record 308,084 from a year earlier to 125,583,658, marking eighth consecutive year of declines, government data show
Dirty Asian girls in really wet porn scenes - they blow cocks ready to shoot, they take them up their pussy and ass cause thats what they strive for
Having joined the ranks of advanced economies, Singapore can endure slower growth and still maintain absolute real economic gains similar to those of the past and of other countries. In other words, incomes here today may need to grow just 2 per cent to rise by the same absolute amount as a 10 per cent increase in the past, or a 10 per cent increase in another country. ...
9月26日「中秋节快乐「"最近几天3烟霾很多3大家心情都比较烦一点》今天烟霾被风吹到别的地方了3我们今天晚上可以看到一个圆圆的明月3非常地高兴》所以3但愿人长久3千里共婵娟》" 李显龙总理 Lee Hsien Loong 今晚出席德义区的中秋活动时3祝福大家中秋节快乐》中秋前夕3全岛各地纷纷举行庆中秋活动》当中3德义区傍晚更吸引了5000个居民聚集在碧山-宏茂桥公园3齐庆中秋 ...
Download and look at thousands of study documents in Asian literature on Docsity. Find notes, summaries, exercises for studying Asian literature!
Please do not believe all the talk about the green shoots of the Japanese economy, which I suspect you might have heard. We are in pretty bad shape. ...
Caucasians News by Date. Find breaking news, commentary, and archival information about Caucasians From The latimes (Page 3 of 5)
Explain the Asian Migration Hypothesis in detail. According to the theory, how did natives gradually spread over the continent in subsequent.
... who carried - wallstreet forex, forex free custom forex charts custom, what time does the asian forex market open
Han, C. W.; Choksi, T.; Milligan, C.; Majumdar, P.; Manto, M.; Cui, Y.; Sang, X.; Unocic, R. R.; Zemlyanov, D.; Wang, C,; Ribeiro, F. H.; Greeley, J.; Ortalan, V.. ...
Han, C. W.; Choksi, T.; Milligan, C.; Majumdar, P.; Manto, M.; Cui, Y.; Sang, X.; Unocic, R. R.; Zemlyanov, D.; Wang, C,; Ribeiro, F. H.; Greeley, J.; Ortalan, V.. ...
CONCLUSIONS: Asian subjects were generally 15-20 Kgs lighter, with fewer psoriatic arthritis, shorter disease duration since diagnosis, and higher baseline severity compared to western subjects. Better efficacy had been found in some studies such as secukinumab, brodalumab, ixekizumab, and tofacitinib in Japanese groups. The safety in Asian trials was generally compatible with the pivotal studies, except for the occurrence of active tuberculosis in the infliximab trial in China. Additional indications of pustular and erythrodermic psoriasis are approved in Japan for some of the agents based on phase II/III studies.. ...
TY - JOUR. T1 - Cognitive function, body mass index and mortality in a rural elderly Chinese cohort. AU - Gao, Sujuan. AU - Jin, Yinlong. AU - Unverzagt, Frederick. AU - Cheng, Yibin. AU - Su, Liqin. AU - Wang, Chenkun. AU - Ma, Feng. AU - Hake, Ann. AU - Kettler, Carla. AU - Chen, Chen. AU - Liu, Jingyi. AU - Bian, Jianchao. AU - Li, Ping. AU - Murrell, Jill R.. AU - Clark, Daniel. AU - Hendrie, Hugh. PY - 2014. Y1 - 2014. N2 - Background: Previous studies have shown that poor cognition and low body mass index were associated with increased mortality. But few studies have investigated the association between cognition and mortality across the entire cognitive spectrum while adjusting for BMI. The objective of this study is to examine the associations between cognitive function, BMI and 7-year mortality in a rural elderly Chinese cohort. Methods: A prospective cohort of 2,000 Chinese age 65 and over from four rural counties in China were followed for 7-years. Cognitive function, BMI and other ...
Minimally Invasive Modified Bentall Operation in a Young Chinese Male with Severe Aortic Regurgitation Secondary to Infective Endocarditis in the Backgrou
Xeroderma pigmentosum group C (XPC) is a key component of the nucleotide excision repair (NER) pathway. Dysfunctional XPC protein may impair NER-mediated DNA repair capacity and further lead to genomic instability and carcinogenesis. Two common nonsynonymous polymorphisms in the XPC gene, Lys939Gln (rs2228001 A > C) and Ala499Val (rs2228000 C > T), have been investigated in various types of cancer. We genotyped these two polymorphisms in 1141 cases with histologically confirmed colorectal cancer (CRC) and 1173 healthy controls to explore their causative association with CRC susceptibility. Overall, no association was observed between these two variants and the risk of CRC. Our meta-analysis also confirmed a lack of overall association. Stratified analyses were performed by age, gender, smoking status, pack-year, drinking status, tumor sites, and Dukes stages. We found that XPC Lys939Gln polymorphism was significantly associated with an increased CRC risk in subjects at 57 years of age or younger
BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies covering a wide range of subjects in life sciences and medicine. The journal is divided into 55 subject areas.
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
BACKGROUND Previous studies support Becks cognitive model of vulnerability to depression. However, the relationship between his cognitive triad and other clinical features and risk factors among those with major depression (MD) has rarely been systematically studied. METHOD The three key cognitive symptoms of worthlessness, hopelessness and helplessness were assessed during their lifetime worst episode in 1970 Han Chinese women with recurrent MD. Diagnostic and other risk factor information was assessed at personal interview. Odds ratios (ORs) were calculated by logistic regression. RESULTS Compared to patients who did not endorse the cognitive trio, those who did had a greater number of DSM-IV A criteria, more individual depressive symptoms, an earlier age at onset, a greater number of episodes, and were more likely to meet diagnostic criteria for melancholia, postnatal depression, dysthymia and anxiety disorders. Hopelessness was highly related to all the suicidal symptomatology, with ORs ranging
PLOS ONE: March 7, 2013. The burden of stroke is disproportionately high in the South Asian subcontinent with South Asian ethnicity conferring a greater risk of ischemic stroke than European ancestry regardless of country inhabited. While genes associated with stroke in European populations have been investigated, they remain largely unknown in South Asians. We conducted a comprehensive meta-analysis of known genetic polymorphisms associated with South Asian ischemic stroke, and compared effect size of the MTHFR C677T-stroke association with effect sizes predicted from homocysteine-stroke association. Electronic databases were searched up to August 2012 for published case control studies investigating genetic polymorphisms associated with ischemic stroke in South Asians. Read more. ...
From different parts of the world, South Asian ethnicity has been reported to be an independent risk factor for cardiovascular events [1, 18], although survival thereafter does not seem to be worse compared to Caucasians [19, 20]. We studied the effect of MBL genotype and level in a group of type 2 diabetic subjects of South Asians descent.. The main finding of the present study is that in type 2 diabetic South Asians, the O/O MBL genotype was significantly associated with the occurrence of cardiovascular events compared to wild-type.. The association between low MBL genotype and cardiovascular events has previously been reported in different populations [12, 21, 22]. For instance, the Strong Heart Study included American Indians [12], which - like South Asians-have a high burden of diabetes and subsequent vascular complications. A low MBL genotype was associated with a threefold increased risk for coronary heart disease.. With respect to serum MBL levels and cardiovascular events, data are more ...
RESULTS: We found that the most prevalent genotype was Apo Eε3/3, followed in order by Apo Eε3/4 and Apo Eε2/2. The estimated ApoE allelic frequencies in individuals with SD were 0.095, 0.560, and 0.345 for ε2, ε3, and ε4, respectively. In controls, the corresponding Apo E allelic frequencies were 0.146, 0.699, and 0.155. The percentage of ε4 allele carriers in SD group was significantly higher than that in control group ( ...
Get information, facts, and pictures about Evenki (Asian people) at Encyclopedia.com. Make research projects and school reports about Evenki (Asian people) easy with credible articles from our FREE, online encyclopedia and dictionary.
Last month I pointed to a paper on Chinese population structure, Genomic Dissection of Population Substructure of Han Chinese and Its Implication in Association Studies. One to note was that the average FST differentiation Han populations was on the order of 0.002, while those differentiating Europeans was on the order of 0.009. Below are the various Han population, along with Japanese. CHB = Beijing, while CHD = Denver. The Denver sample is probably biased toward Cantonese and Fujianese, since most American Chinese are from these two groups. As a point of reference, here are South Asian genetic distances. ...
Overall, the prevalence of unmet need was 16.2% for hospitalization service. Among predisposing factors, only educational level was statistically significant. Individuals with higher education were less likely to report unmet needs. Among enabling factors, residential area, social support, personal yearly income and personal healthcare expenditure were strongly associated with the presence of unmet need. Those with less enabling resources (e.g. residing in rural areas) were more likely to report unmet need [Odds ratio (OR) = 1.5-6.5]. All the need factors, except for physical function, were strongly associated with the presence of unmet need. Seniors in poorer health (e.g. in fair or poor health) were more likely to report unmet need than their counterparts in better health (OR = 1.5-2.8).. ...
The design of the Singapore Chinese Health Study has been described in detail elsewhere (6) . Briefly, 63,257 Chinese men (27,959) and women (35,298) ages 45-74 years were recruited into the population-based residential cohort between April 1993 and December 1998. Eighty-five percent of eligible subjects participated in the study. At recruitment, each participant was interviewed in-person by a trained interviewer using a subsequently validated 165-item food frequency questionnaire. The structured questionnaire also requested demographic information, lifetime use of tobacco, current alcohol drinking pattern, current physical activity profile, reproductive history (women only), occupational exposures, medical history, and family history of cancer.. There are seven common soyfoods (all are nonfermented) in the Singapore Chinese diet, including plain tofu, taupok, taukwa, foopei, foojook, tofu-far, and soybean drink. Taupok is taukwa plus oil and tofu-far is tofu plus syrup. We used the following ...
We replicated previous findings that a SNP (rs4430796) in intron 2 of HNF1β was significantly associated with type 2 diabetes in our Chinese population. Our results are consistent with those reported by Gudmundsson et al. (12), and the effect size of the at-risk G allele for rs4430796 in our Chinese subjects (OR 1.16) is quite similar to that determined by the DECODE findings (for the G allele, overall OR 1.10). Notably, the allele frequency for the SNP rs4430796 is quite different between different ethnic groups. The at-risk G allele for rs4430796 had a frequency of 0.25-0.30 in the Chinese population but a frequency of 0.47-0.54 and 0.70-0.73 in Caucasians and West Africans, respectively (11,12). Although the minor G allele identified in the Chinese and Caucasian populations is the major allele in West Africans, this allele showed the same direction of its effect for type 2 diabetes. rs4430796 was not significantly associated with type 2 diabetes in Hong Kong Chinese, although the effect ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
The Effects of Genetic Variation in FTO rs9939609 on Obesity and Dietary Preferences in Chinese Han Children and Adolescents. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
BACKGROUND: Transforming growth factor β (TGFβ) is an important immunoregulatory cytokine in regulatory T cell (Treg) and Th17-mediated pathology, including uveitis due to Behçets disease (BD). Of the three isoforms, TGFβ2 is found at highest levels in the aqueous humour of uninflamed eyes. TGFβ signals through a cell-surface receptor comprising three subunits (TGFBR1, 2 and 3). TGFBR3 is considered necessary for TGFβ2 signal transduction, but not for other isoforms. A polymorphism in TGFBR3 (rs1805110) has previously been identified in Han Chinese patients with BD. We investigated the frequency of this polymorphism in a Caucasian population with BD and idiopathic intermediate uveitis (IIU).. METHODS: The single-nucleotide polymorphism (SNP) rs1805110 in TGFBR3 was genotyped in 75 BD patients, 92 IIU disease controls and 85 disease-free controls. The association with both diseases was analysed using Fishers exact test.. RESULTS: No significant difference in rs1805110 allele or genotype ...
Publication date: July 2019Source: Biomedical and Environmental Sciences, Volume 32, Issue 7Author(s): Xue Yan WU, Lin LIN, Qi Hong Yan, Rui DU, Chun Yan HU, Li Na MA, Kui PENG, Mian LI, Yu XU, Min XU, Yu Hong CHEN, Jie Li LU, Yu Fang BI, Wei Qing WANG, Guang NING...
Read more about Bong Joon Hos Parasite is first South Korean film to win international feature Oscar on Business Standard. Director Bong Joon Hos Parasite scripted history at the Oscars by becoming the first South Korean film to be nominated and win in the international feature category at the 92nd Academy Awards.It was the second Oscar win of the night for the
Body mass index is positively associated with blood pressure, according to the ongoing study of 1.7 million Chinese men and women being conducted by researchers at the Yale Center for Outcomes Research and Evaluation (CORE) and in China. The research was published in JAMA Network Open.
According to research published in the August issue of the Journal of the American Medical Association, four common variants of a gene have been implicated in renal disease development in Chinese patients with type 2 diabetes.Kidney failure is a common cause of death among diabetic individuals, and Asian populations seem to be particularly at risk.
Amid mounting pressure from the public, Seoul and Washington have sealed a legally-binding agreement that facilitates new rules for shipping biological samples by the US. From now on the USFK has to report the quantity, type and purpose of any biological samples, as well as provide information about the senders and recipients, with the Korea Customs Service having the authority to oversee the shipments. ...
Results In total, 319 children from the cohort were included. Having a fever (hazard ratio 1.80, 95% CI 1.10, 2.93), any part South Asian ethnicity (HR 1.75, 95% CI 1.04, 2.95), highly educated parents (HR 1.69, 95% CI 1.18, 2.44), and limp (HR 1.55, 95% 1.16, 2.06) were significantly associated with shorter time from symptom onset to first PR assessment, while a history of heel pain or enthesitis (HR 0.61, 95% 0.38, 0.97) was significantly associated with a longer time to first PR visit. ...
Novaerus has partnered with powerhouse distributor, Gatevision, to launch its air dis-infection solutions to the South Korean Market. Gatevision launched two Novaerus…
Grouping people from the continent of Asia, which holds more than half of the worlds population, together into a single group is obviously not optimal, but it is whats available. In this context, it understates the difficulty people of Asian descent living in the US have in finding an acceptable mate who shares their ancestry. Grouping Hispanics of all races into a single category presents similar problems.. Graphs depicting data from the tables above follow. The race and gender in each graphs title is married to or cohabitating with members of the opposite sex at the rates depicted. Keep in mind that the comparisons are among those of the same sex and gender who are in the same living situation. That is, the first graph shows the percentage of married white women, not of all white women, who are married to men of the various racial groups. The color coding is designed to be intuitive and is as follows: White = whites, Black = blacks, Brown = Hispanics, Yellow = Asians, Red = others ...
A dark, rich, and satisfying English mixture of Orientals, Virginias, Carolinas, and Cyprian Latakia. A sweet, soft, pleasant smelling, American style English.
Orientals develop close bonds with their owners. If they are left alone for long periods they may show signs of depression. Learn more...
Dr Kim and colleagues from California, USA compared the prevalence of non-obese NAFLD in women with or without PCOS, and assessed an independent association between PCOS and NAFLD in a non-obese Asian cohort ...
Last night, Sods was the very picture of intoxicated multiculturalism: an Irish pub, in a traditionally Peranakan neighbourhood, with imbibers ranging from muted, middle-aged Indian men to loud Chinese people to a girl in a neat black top that I kept admiring from a distance (hope she didnt think I was admiring the guy she was with) to interracial couples (including the pub owners, the Bs and yours truly, though we dont look it) to an older Eurasian couple that seems to be happily growing old together to a totally blotto gentleman whod apparently been drinking for nine hours and, fortunately, had a friend to prop him up on his way out, or hedve fallen sideways onto the pavement and probably stayed there unable to get up till this morning. Earlier in the evening, a couple in their early twenties paced cautiously up the courtyard, peered into the bar, and promptly turned around and walked right back out onto the street. Were they expecting Zouk ...
One of the great things about visiting Japan for the IMF/WB meetings is that I will have a chance to talk about the contribution the Japanese people have made to immunization. The Japanese people have become the worlds strongest supporters of
Oncotarget | https://doi.org/10.18632/oncotarget.23660 Yuji Shimizu, Shimpei Sato, Jun Koyamatsu, Hirotomo Yamanashi, Mako Nagayoshi, Koichiro Kadota, Shin-Ya Kawashiri, Takahiro Maeda
After being around the block many times back in your own country and finally realizing that the traits you are looking for in a wife cannot be found among the women from your own culture, you give cross-cultural relationships a shot and find out that Chinese women possess desirable traits that make them the best lifetime partners.
Kidnappers have snatched a second U.S. businessman off the streets of Tijuana. Though the victims are both of Asian descent and the two abductions took place within the space of a week, authorities do not believe the cases are connected. KPBS reporter Amy Isackson has details.
New Forbes magazine list of most powerful women in the world includes nine Chinese women, a sign of womens growing power in Chinese society
Asians Big Tits and Japanese big boobs adult tube with free asian porn, chinese porn, korean porn,free japanese porn and asian girls sex videos.
BEIJING - At least 65 people were killed Saturday by an explosion at an eastern Chinese automotive parts factory that supplies General Motors, state media reported.
Results Highly frequent shopping compared to never or rarely predicted survival (HR 0.54, 95% CI 0.43 to 0.67) with adjustment for physical function and cognitive function and other covariates HR was 0.73 (95% CI 0.56 to 0.93). Elderly who shopped every day have 27% less risk of death than the least frequent shoppers. Men benefited more from everyday shopping than women with decreased HR 28% versus 23% compared to the least. ...
You may have already known that soybeans are used in many Japanese dishes. Soybeans are very nutritious and versatile to cook. Japanese people have benefitted
Hamster is the best porn site to Charlotte from Essex hot teen girl shows her naked body. Watch these hot girls go crazy when knob is in their face XXX Videos these hot girls go crazy when knob is Handsome man is about to have sex with 2 hot girls. FREE videos found on Lots of japanese women lactating and breastfeeding their gigantic titty milk.. ...
Most noticeable on CEATEC Japan for those of us who dont live in Japan was a host of robotic and sensor products programmed to talk, think, and behave like Japanese people, mirroring Japanese sensibilities, preferences, and habits.
With the numbers of Filipinos vacationing and working in Singapore, our awareness for Singaporean food has quickly risen, triggering shops that offer this distinct cuisine everywhere in the Metro. Even famous Singaporean chains have set up shop here. Nevertheless, its … Continue reading →. ...
Ive been known to relentlessly express concerns over Chinas geopolitical ambitions and military buildup, but now Im forced to report that the Chinese are also leaving us behind in urban design: Thats a new pedestrian bridge in Hunan Province, built to resemble Chinese knots (whatever those are). There are a lot more pictures at the…
Map of Shanghai Blues Chinese Restauarant, Oludeniz: Locate Oludeniz hotels for Shanghai Blues Chinese Restauarant based on popularity, price, or availability, and see TripAdvisor reviews, photos, and deals.
Background: Sugar-sweetened carbonated beverages (called soft drinks) and juices, which have a high glycemic load relative to other foods and beverages, have been hypothesized as pancreatic cancer risk factors. However, data thus far are scarce, especially from non-European descent populations. We investigated whether higher consumption of soft drinks and juice increases the risk of pancreatic cancer in Chinese men and women.. Methods: A prospective cohort analysis was done to examine the association between soft drink and juice consumption and the risk of pancreatic cancer in 60,524 participants of the Singapore Chinese Health Study with up to 14 years of follow-up. Information on consumption of soft drinks, juice, and other dietary items, as well as lifestyle and environmental exposures, was collected through in-person interviews at recruitment. Pancreatic cancer cases and deaths were ascertained by record linkage of the cohort database with records of population-based Singapore Cancer ...
PURPOSE: To determine whether the main mitochondrial DNA (mtDNA) haplogroups of the Han people have an impact on long-term clinical outcome. METHODS: We prospectively studied 181 individuals who were sequentially admitted to the intensive care unit. Demographic and clinical data were recorded along with clinical outcome over 180 days. Follow-up was completed for all study participants. We then determined the mtDNA haplogroups of the patients and 570 healthy, age-matched Han people from Zhejiang province, Southeast China, by analyzing sequences of hypervariable mtDNA segments and testing diagnostic polymorphisms in the mtDNA coding region with DNA probes. RESULT: The frequency of the main subhaplogroups of the Han population in the study cohort did not differ significantly from the control group. mtDNA haplogroup R, one of the three main mtDNA haplogroups of the Han people, was a strong independent predictor for the outcome of severe sepsis, conferring a 4.68-fold (95% CI 1.903-10.844, P = 0.001) ...
The present investigation was undertaken to study the genetic polymorphism of the DRB3 exon 2 in 75 crossbred cattle by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. Five genotypes i.e. HaeIII-a, HaeIII-b, HaeIII-e, HaeIII-ab and HaeIII-ae were observed when the 284 bp PCR products were digested with HaeIII restriction enzyme. The corresponding frequencies of these patterns were 0.53, 0.04, 0.01, 0.38 and 0.04, respectively. Digestion with RsaI restriction enzyme resolved 24 different restriction patterns. The frequencies of these patterns ranged from 0.013 (RsaI-f, RsaI-k and RsaI-c/n) to 0.120 (RsaI-n). The results revealed that the crossbred cows belonged to the RsaI patterns namely b, k, l, a/l, d/s, l/n, l/o and m/n, whose corresponding frequencies were 0.027, 0.013, 0.040, 0.027, 0.040, 0.067, 0.027 and 0.067, respectively. Digestion of the 284 bp PCR product of DRB3.2 gene with PstI in the crossbred cattle did not reveal any restriction site. ...
Background: More than 60 genetic susceptibility loci associated with type 2 diabetes mellitus (T2DM) have been established in populations of Asian and European ancestry. Given ethnic differences and environmental factors, validation of the effects of genetic risk variants with reported associations identified by Genome-Wide Association Studies (GWASs) is essential. The study aims at evaluating the associations of T2DM with 29 single nucleotide polymorphisms (SNPs) from 19 candidate genes derived from GWASs in a northern Han Chinese population. Method: In this case-control study, 461 T2DM-diagnosed patients and 434 controls were recruited at the Jidong oil field hospital (Hebei, China) from January 2009 to October 2013. A cumulative genetic risk score (cGRS) was calculated by summation of the number of risk alleles, and a weight GRS (wGRS) was calculated as the sum of risk alleles at each locus multiplied by their effect sizes for T2DM, using the independent variants selected. Result: The allelic
South Asian populations are the largest visible minority group in Canada; however, there is very little information on the mental health of these populations. The objective of this study was to determine the prevalence rates and characteristics of mental health outcomes for South Asian first-generation immigrant and second-generation Canadian-born populations. The Canadian Community Health Survey (CCHS) 2011 was used to calculate the estimated prevalence rates of the following mental health outcomes: mood disorders, anxiety disorders, fair-poor self-perceived mental health status, and extremely stressful life stress. The characteristics associated with these four mental health outcomes were determined through multivariate logistic regression analysis of merged CCHS 2007-2011 data. South Asian Canadian-born (3.5%, 95% CI 3.4-3.6%) and South Asian immigrant populations (3.5%, 95% CI 3.5-3.5%) did not vary significantly in estimated prevalence rates of mood disorders. However, South Asian immigrants
Aims: Several studies indicated that CYP2C19 loss-of-function polymorphisms have a higher risk of stent thrombosis (ST) after percutaneous coronary interventions (PCIs). However, this association has not been investigated thoroughly in Chinese population. In this study, we aimed to determine the effect of CYP2C19 loss-of-function polymorphisms on the occurrence of ST and other adverse clinical events in Chinese population.. Methods: The study population included 1 068 consecutive patients undergoing intracoronary stent implantation after pre-loading with 600mg of clopidogrel. CYP2C19*2 and CYP2C19*3 were genotyped by use of polymerase chain reaction-restriction fragment length polymorphism analysis. The adverse clinical events recorded were ST, death, myocardial infarction, and bleeding events. The primary end point of the study was the incidence of cumulative ST within 1 year following PCI. The secondary end point was other adverse clinical outcomes 1 year after the procedure.. Results: The ...
INTRODUCTION: Low vitamin D status is prevalent among South Asians living in the UK. The relationship, however, between serum 25-hydroxyvitamin D level (25OHD), serum parathyroid level (PTH) and bone mass in this group of women is unknown. The aim of this study was to determine the association between serum PTH, 25OHD and bone mass in a population based sample of young UK South Asian women. MATERIALS AND METHODS: Names of South Asian women aged 18 to 36 years of Pakistani origin living in the Greater Manchester area were identified from primary care registers using validated computer software. Subjects were invited to attend for (i) a blood test for assessment of serum calcium (Ca), albumin, PTH and 25OHD and (ii) for bone mineral density (BMD) scanning using the following: areal BMD at the hip (femoral neck, total hip) and lumbar spine using dual X-ray absorptiometry (Hologic QDR 4500), and volumetric BMD at the distal radius using peripheral quantitative computed tomography (Norland Stratec XCT 2000).

Asian Continental Ancestry Group | Profiles RNSAsian Continental Ancestry Group | Profiles RNS

"Asian Continental Ancestry Group" by people in this website by year, and whether "Asian Continental Ancestry Group" was a major ... "Asian Continental Ancestry Group" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Asian Continental Ancestry Group" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Asian Continental Ancestry Group". ...
more infohttps://profiles.umassmed.edu/display/116949

topic:Asian Continental Ancestry Group - psychology found 42 records • Arctic Healthtopic:"Asian Continental Ancestry Group - psychology" found 42 records • Arctic Health

European Continental Ancestry Group - psychology 11 * Asian Continental Ancestry Group - psychology - statistics & numerical ... Asian Continental Ancestry Group - psychology China - ethnology Emigration and Immigration Ethnopsychology Female Focus Groups ... Asian Continental Ancestry Group - psychology Canada Child Child, Preschool Cross-Cultural Comparison European Continental ... Asian Continental Ancestry Group - psychology Chemical Hazard Release - psychology Disasters Ego Female Humans Male Middle Aged ...
more infohttps://arctichealth.org/en/list?q=topic%3A%22Asian+Continental+Ancestry+Group+-+psychology%22&p=1&ps=&sort=title_sort+asc

Asian Continental Ancestry Group | Profiles RNSAsian Continental Ancestry Group | Profiles RNS

"Asian Continental Ancestry Group" by people in this website by year, and whether "Asian Continental Ancestry Group" was a major ... "Asian Continental Ancestry Group" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Asian Continental Ancestry Group" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Asian Continental Ancestry Group". ...
more infohttp://profiles.ouhsc.edu/display/66837

Whats New for 2004 MeSH. NLM Technical Bulletin. 2003 Nov-DecWhat's New for 2004 MeSH. NLM Technical Bulletin. 2003 Nov-Dec

Asian Continental Ancestry Group. M1.686.508.200. Asian Americans. M1.686.508.200.100. European Continental Ancestry Group. ... Recent genetic research indicates that the degree of genetic heterogeneity within groups and homogeneity across groups make ... Ethnic Groups and Geographic Origins Categories I and M:. The MeSH descriptor Racial Stocks,and its four children (Australoid ... Other revised chemical groups include Xanthones and Flavonoids. Many of the flavones required retreeing to the appropriate area ...
more infohttps://www.nlm.nih.gov/pubs/techbull/nd03/nd03_mesh.html

Smoking cessation and mortality among middle-aged and elderly Chinese in Singapore: the Singapore Chinese Health Study |...Smoking cessation and mortality among middle-aged and elderly Chinese in Singapore: the Singapore Chinese Health Study |...

Asian Continental Ancestry Group. *carcinogens. *global health. *prevention. *smoking-caused disease. *secondhand smoke ... Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to ... Copyright © 2019 BMJ Publishing Group Ltd. All rights reserved.. 京ICP备15042040号-3 ...
more infohttps://tobaccocontrol.bmj.com/content/22/4/235

Beta-blocker prescription among Japanese cardiologists and its effect on various outcomes.Beta-blocker prescription among Japanese cardiologists and its effect on various outcomes.

Considering the vast amount of evidence showing their benefits in this group of patients, the aim of the present study was to ... Asian Continental Ancestry Group. Cardiology / methods, trends. Coronary Artery Disease / drug therapy*, mortality. Drug ... From this group, 4,160 (30.1%) patients were prescribed beta-blockers at the time of discharge. These patients were ... Considering the vast amount of evidence showing their benefits in this group of patients, the aim of the present study was to ...
more infohttp://www.biomedsearch.com/nih/Beta-Blocker-Prescription-Among-Japanese/20234099.html

Safety and effectiveness responses to etanercept for rheumatoid arthritis in Japan: a sub-analysis of a post-marketing...Safety and effectiveness responses to etanercept for rheumatoid arthritis in Japan: a sub-analysis of a post-marketing...

Asian Continental Ancestry Group. Chi-Square Distribution. Drug Substitution. Drug Therapy, Combination. Female. Humans. ... The largest group of patients (1,593) had RA for between 5 and 10 years, while the next largest group (1,214) had RA for ... Because the present PMS study evaluated a very large group of patients, dividing groups according to duration with RA and also ... The smallest group of patients (707) had RA for less than 2 years. The patients with longer duration of RA were older and had ...
more infohttp://www.biomedsearch.com/nih/Safety-effectiveness-responses-to-etanercept/21327436.html

CYP2C19 | Cancer Genetics WebCYP2C19 | Cancer Genetics Web

Asian Continental Ancestry Group. *Genetic Predisposition. *Antineoplastic Agents, Hormonal. *Stereoisomerism. *Spectrometry, ... in group 2, P = 0.014, 95 % confidence interval (CI)). The differences were statistically significant between group 1 and group ... This research covered the above two factors and divided the patients with PLC into two groups (one group with HBV infection and ... Eight hundred sixty-four cancer-free Han people (controls, named group 1), 207 Han PLC patients with HBV infection (group 2), ...
more infohttp://www.cancerindex.org/geneweb/CYP2C19.htm

IL12B | Cancer Genetics WebIL12B | Cancer Genetics Web

Asian Continental Ancestry Group. *Interleukin-10. *Stomach Cancer. Tag cloud generated 16 March, 2017 using data from PubMed, ... the AA genotype and A allele were less frequent in the group with low-grade cervical lesions than in group with high-grade ... The genotype distributions of IL-6 (-174 C/G) genotype were similar between the cases and the control groups; however, among ... Asian Pac J Cancer Prev. 2014; 15(18):7869-73 [PubMed] Related Publications ...
more infohttp://www.cancerindex.org/geneweb/IL12B.htm

The location of the mental foramen in a selected Malay population  - CogprintsThe location of the mental foramen in a selected Malay population - Cogprints

Asian Continental Ancestry Group; Humans; Radiography, Panoramic. Subjects:. JOURNALS. JOURNALS , Online Journal of Health and ... Adolescent; Adult; Article; Asian; Chin; Female; Histology; Human; Malaysia; Male; Mandible; Panoramic Radiography; Radiography ...
more infohttp://cogprints.org/8181/index.html

Trans-ancestry Mutational Landscape of Hepatocellular Carcinoma Genomes - PubMedTrans-ancestry Mutational Landscape of Hepatocellular Carcinoma Genomes - PubMed

Asian Continental Ancestry Group Actions. * Search in PubMed * Search in MeSH * Add to Search ... Trans-ancestry Mutational Landscape of Hepatocellular Carcinoma Genomes Yasushi Totoki 1 , Kenji Tatsuno 2 , Kyle R Covington 3 ... Trans-ancestry Mutational Landscape of Hepatocellular Carcinoma Genomes Yasushi Totoki et al. Nat Genet. 2014 Dec. . ... Differences in somatic mutation landscape of hepatocellular carcinoma in Asian American and European American populations. Yao ...
more infohttps://pubmed.ncbi.nlm.nih.gov/25362482/

Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)

Categories: Asian Continental Ancestry Group Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
more infohttps://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Asian+Continental+Ancestry+Group&parentid=42254&catid=42251

Comparison of PK parameters clearance and exposure betw | Open-iComparison of PK parameters clearance and exposure betw | Open-i

Comparison of PK parameters clearance and exposure between non-Asian and Asian patients following multiple infusions of ... Asian Continental Ancestry Group. *Dose-Response Relationship, Drug. *Drug Administration Schedule. *Female ... White circles (○) = CLss, non-Asian patients; black circles (•) = CLss, Asian patients; white triangles (▵) = AUCτ, non-Asian ... White circles (○) = CLss, non-Asian patients; black circles (•) = CLss, Asian patients; white triangles (▵) = AUCτ, non-Asian ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4317910_cas0105-0862-f3&req=4

Hong Kong men with low incomes have worse health-related quality of life as judged by SF-36 scores | HKMJHong Kong men with low incomes have worse health-related quality of life as judged by SF-36 scores | HKMJ

Key words: Asian continental ancestry group; Hong Kong; Income; Quality of life ... The distribution of income was 30% in high-, 54.8% in middle-, and 15.2% in low-income groups. Women had similar SF-36 scores ... The subjects were categorised into three income groups according to monthly income in Hong Kong dollars (low, 10 000-25 000; ... among different income groups. In men, for most variables there was a significant positive linear correlation between income ...
more infohttp://www.hkmj.org/abstracts/v12n5/351.htm

HKU Scholars Hub: A novel mutation of Arg306 of factor V gene in Hong Kong chineseHKU Scholars Hub: A novel mutation of Arg306 of factor V gene in Hong Kong chinese

Asian Continental Ancestry Group. en_HK. dc.subject.mesh. Factor V - genetics. en_HK. ...
more infohttp://hub.hku.hk/handle/10722/49067

multiple sclerosis  - BioMedLib™ search enginemultiple sclerosis - BioMedLib™ search engine

Asian Continental Ancestry Group. Enzyme Activation / genetics. Female. Gene Frequency. Gene Silencing. Genotype. Humans. Male ... Group. A2.9.1. Professional or Occupational Group. A2.9.2. Population Group. A2.9.3. Family Group. A2.9.4. Age Group. A2.9.5. ... And for these age groups: Newborn: birth to 1 month. Infant: 1 to 23 months. Preschool child: 2 to 5 years. Child: 6 to 12 ... Additionally, Asian or low latitude (20.1-30°N) people with ApaI homozygous genotype, , 2013 publication year people in the ...
more infohttp://bmlreview.com/?kwr=multiple+sclerosis&smntc=gene+or+genome&kwr=&ck=&cxts=10&fntszff=100&hghlght=maroon&srtrdr=relevance&annttn=none&pdthm=2010&hqryhstry=5062b3f288e4d101&pgwdth=100&mld=&wft=wims&b4s=614881810

multiple sclerosis  - BioMedLib™ search enginemultiple sclerosis - BioMedLib™ search engine

Asian Continental Ancestry Group. Enzyme Activation / genetics. Female. Gene Frequency. Gene Silencing. Genotype. Humans. Male ... Group. A2.9.1. Professional or Occupational Group. A2.9.2. Population Group. A2.9.3. Family Group. A2.9.4. Age Group. A2.9.5. ... And for these age groups: Newborn: birth to 1 month. Infant: 1 to 23 months. Preschool child: 2 to 5 years. Child: 6 to 12 ... Additionally, Asian or low latitude (20.1-30°N) people with ApaI homozygous genotype, , 2013 publication year people in the ...
more infohttp://bmlreview.com/?kwr=multiple+sclerosis&smntc=gene+or+genome&kwr=&ck=&cxts=10&fntszff=100&hghlght=maroon&srtrdr=relevance&annttn=none&pdthm=2010&hqryhstry=5062b3f288e4d101&pgwdth=100&mld=&wft=wims&b4s=851542823

malignant lymphoma of small intestine drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search enginemalignant lymphoma of small intestine drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine

Asian Continental Ancestry Group. Humans. Japan. Male. Remission Induction. Transplantation, Autologous. Tumor Burden ... The nonleukemic period after the diagnosis of GS was significantly longer in Group III than in the other groups (median, 12 ... These patients were divided into 3 groups by therapeutic regimens; Group I included 12 patients who received only biopsy or ... And for these age groups: Newborn: birth to 1 month. Infant: 1 to 23 months. Preschool child: 2 to 5 years. Child: 6 to 12 ...
more infohttp://www.bmlsearch.com/?kwr=malignant+lymphoma+of+small+intestine+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1

stage i childhood precursor lymphoblastic lymphoma drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search enginestage i childhood precursor lymphoblastic lymphoma drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine

Asian Continental Ancestry Group. Asparaginase / therapeutic use. Child. Child, Preschool. China. Cyclophosphamide / ... Group. A2.9.1. Professional or Occupational Group. A2.9.2. Population Group. A2.9.3. Family Group. A2.9.4. Age Group. A2.9.5. ... Cooperative study group for childhood acute lymphoblastic leukemia (COALL) and Pediatric Oncology Group studies. ... And for these age groups: Newborn: birth to 1 month. Infant: 1 to 23 months. Preschool child: 2 to 5 years. Child: 6 to 12 ...
more infohttp://www.bmlsearch.com/?kwr=stage+i+childhood+precursor+lymphoblastic+lymphoma+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1

Irish Child Health Database. Department of Health and ChildrenIrish Child Health Database. Department of Health and Children

Irish Child Health Database » » A » Asian Continental Ancestry Group/ ethnology Asian Continental Ancestry Group/ ethnology. ...
more infohttp://www.childrensdatabase.ie/Irish-child-health-database/list.asp?KID=9056

FST profile for nine genes with a significantly higher  | Open-iFST profile for nine genes with a significantly higher | Open-i

African Continental Ancestry Group. *Asian Continental Ancestry Group. *China. *Databases, Genetic. *European Continental ... Conclusion: These results suggest a possible basis for varying susceptibility to CVD among ethnic groups. ... Conclusion: These results suggest a possible basis for varying susceptibility to CVD among ethnic groups. ... of a set of genes in etiologic pathways of CVD among 3 ethnic groups: Yoruba in Nigeria (YRI), Utah residents with European ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC1937006_1471-2156-8-48-6&req=4

Related GMR Articles | GMR | Genetics and Molecular Research | The Original by FUNPEC-RPRelated GMR Articles | GMR | Genetics and Molecular Research | The Original by FUNPEC-RP

Asian Continental Ancestry Group; China; Chromosomes, Human, X; Chromosomes, Human, Y; DNA fingerprinting; Ethnic groups; ...
more infohttps://www.geneticsmr.com/related/8629

Welcome to LibAge, the ageing reference resourceWelcome to LibAge, the ageing reference resource

Entries tagged Asian Continental Ancestry Group/genetics (14). Sort:. Number of citations. Author. Title. Year. PubMed ID. ... 2003) "Angiotensin I-converting enzyme gene polymorphism in two ethnic groups living in Brazils southern region: association ... Integrative Genomics of Ageing Group Our lab leads the upkeep and development of HAGR. ...
more infohttp://libage.ageing-map.org/entries/tags/1586/

Related GMR Articles | GMR | Genetics and Molecular Research | The Original by FUNPEC-RPRelated GMR Articles | GMR | Genetics and Molecular Research | The Original by FUNPEC-RP

Asian Continental Ancestry Group; China; Gene frequency; Genetic predisposition to disease; Genotype; Humans; Interleukin-1beta ... especially those that use materials from different heterotic groups. These studies are also useful in tropical environments and ...
more infohttps://geneticsmr.com/related/8018
  • This genetic connection between the ancestors of the Andamanese and South Asian tribal groups ~30 kya has important implications for the debate concerning migration routes and settlement patterns of humans leaving Africa during the late Pleistocene, and indicates the need for more detailed genotyping strategies. (edu.au)
  • Asian flushing: genetic and sociocultural factors of alcoholism among East asians. (umassmed.edu)
  • Past research showed that East Asians' belief in holism was expressed as their tendencies to include background facial emotions into the evaluation of target faces more than North Americans. (arctichealth.org)
  • In three studies, European Canadians and East Asians rated the intensity of target facial emotions surrounded with either affectively salient landscape sceneries or background facial emotions. (arctichealth.org)
  • Rushton argues that race is a valid biological concept and that racial differences frequently arrange in a continuum across 60 different behavioral and anatomical variables, with "Mongoloids" (East Asians) at one end of the continuum, "Negroids" (Sub-Saharan Africans) at the opposite extreme, and "Caucasoids" (Europeans, Middle Easterners and North Africans) in the middle. (wikipedia.org)
  • Rushton's book is focused on what he considers the three broadest racial groups, and does not address other populations such as South East Asians and Australian aboriginals. (wikipedia.org)
  • He writes in particular, "Whites and East Asians have wider hips than Blacks. (wikipedia.org)
  • The prevalence of infertility in American Indian/Alaska Natives and other racial/ethnic groups: National Survey of Family Growth. (ouhsc.edu)
  • Mean FST values for common putatively functional variants were significantly higher than FST values for nonfunctional variants.Thus, putative functional SNPs in genes in etiologic pathways for CVD show greater population differentiation than non-functional SNPs and a significant variance of FST values was noted among pairwise population comparisons for different biological processes.These results suggest a possible basis for varying susceptibility to CVD among ethnic groups. (nih.gov)
  • We investigated patterns of population differentiation (FST) of a set of genes in etiologic pathways of CVD among 3 ethnic groups: Yoruba in Nigeria (YRI), Utah residents with European ancestry (CEU), and Han Chinese (CHB) + Japanese (JPT). (nih.gov)
  • These results suggest a possible basis for varying susceptibility to CVD among ethnic groups. (nih.gov)
  • In this report, 3029 women between the ages of 42 and 54 yr from five ethnic groups were studied for 2 yr. (umassmed.edu)
  • The magnitude of this association varied by ethnic group, and the decline in log circulating DHEAS levels with higher log BMI was steepest for Chinese and least steep for Hispanics. (umassmed.edu)
  • 2 model (Gaudreau & Thompson, 2010) and academic outcomes (i.e., academic satisfaction and grade-point average [GPA]) differed across 2 sociocultural groups: Asian Canadians and European Canadians. (arctichealth.org)
  • This graph shows the total number of publications written about "Asian Continental Ancestry Group" by people in this website by year, and whether "Asian Continental Ancestry Group" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Asian Continental Ancestry Group" by people in Profiles. (umassmed.edu)
  • 2 model of perfectionism: a comparison across Asian Canadians and European Canadians. (arctichealth.org)
  • The results showed that, although affectively salient landscapes influenced the judgment of both cultural groups, only European Canadians downplayed the background facial emotions. (arctichealth.org)
  • A sample of 697 undergraduate students (23% Asian Canadians) completed self-report measures of dispositional perfectionism, academic satisfaction, and GPA. (arctichealth.org)