A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)
An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. Scurvy is characterized by bleeding in any tissue, weakness, ANEMIA, spongy gums, and a brawny induration of the muscles of the calves and legs.
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Rats bearing mutant genes which are phenotypically expressed in the animals.
Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.
Plasma glycoproteins that form a stable complex with hemoglobin to aid the recycling of heme iron. They are encoded in man by a gene on the short arm of chromosome 16.
A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).
Detection of RNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane followed by hybridization with labeled NUCLEIC ACID PROBES.

Dietary antioxidants and magnesium in type 1 brittle asthma: a case control study. (1/213)

BACKGROUND: Type 1 brittle asthma is a rare form of asthma. Atopy, psychosocial factors and diet may contribute to this condition. As increased dietary magnesium has a beneficial effect on lung function and selenium, vitamins A, C and E have antioxidant properties, a study was undertaken to test the hypothesis that patients with brittle asthma have diets deficient in these nutrients compared with subjects with non-brittle asthma and healthy adults. METHODS: A case control study of the dietary intakes of 20 subjects with brittle asthma, 20 with non-brittle asthma, and 20 healthy adults was performed using five day weighed dietary records. Intake of magnesium was the primary outcome measure with selenium and vitamins A, C and E as secondary outcomes. Serum levels were measured at the same time as the dietary assessment. RESULTS: Sixty subjects (27 men) of mean age 49.5 years were recruited and completed the study. Subjects with brittle asthma had statistically lower median dietary intakes of vitamins A and E than the other groups (vitamin A: brittle asthma 522.5 micrograms/day, non-brittle asthma 869.5 micrograms/day, healthy adults 806.5 micrograms/day; vitamin E: brittle asthma 4.3 mg/day, non-brittle asthma 4.6 mg/day, healthy adults 4.5 mg/day). Median dietary intakes for the other nutrients were not significantly different between groups. Serum levels were within normal ranges for each nutrient in all subjects. Intakes less than the reference nutrient intake (RNI) for magnesium and vitamins A and C, and less than the safe intake (SI) for vitamin E were more likely in patients with brittle asthma than in those with non-brittle asthma. CONCLUSION: Nutrient deficiency and reduced antioxidant activity may contribute to disease activity in type 1 brittle asthma, although a prospective study of replacement therapy will be needed to confirm this hypothesis.  (+info)

Parenteral vitamin requirements during intravenous feeding. (2/213)

Serum vitamin levels of 40 patients undergoing parenteral nutrition over a 5-to 42-day period were studied while the subjects received daily water-soluble and once weekly fat soluble vitamin formulations intravenously. Initial serum deficiencies of vitamins A, C, and folate were noted in a large portion of the severely malnourished population. At the replacement levels used in this study a small number of patients developed subnormal levels of vitamins A and D. Improvement in levels for vitamin C and folate were noted for most patients. Vitamin B12 deficiencies were not noted in any patient. Currently available commercial vitamin preparations can be used with safety in the parenterally nourished population and recommended guidelines for weekly infusion of both water and fat soluble vitamins are presented.  (+info)

Aortic wall damage in mice unable to synthesize ascorbic acid. (3/213)

By inactivating the gene for L-gulono-gamma-lactone oxidase, a key enzyme in ascorbic acid synthesis, we have generated mice that, like humans, depend on dietary vitamin C. Regular chow, containing about 110 mg/kg of vitamin C, is unable to support the growth of the mutant mice, which require L-ascorbic acid supplemented in their drinking water (330 mg/liter). Upon withdrawal of supplementation, plasma and tissue ascorbic acid levels decreased to 10-15% of normal within 2 weeks, and after 5 weeks the mutants became anemic, began to lose weight, and die. Plasma total antioxidative capacities were approximately 37% normal in homozygotes after feeding the unsupplemented diet for 3-5 weeks. As plasma ascorbic acid decreased, small, but significant, increases in total cholesterol and decreases in high density lipoprotein cholesterol were observed. The most striking effects of the marginal dietary vitamin C were alterations in the wall of aorta, evidenced by the disruption of elastic laminae, smooth muscle cell proliferation, and focal endothelial desquamation of the luminal surface. Thus, marginal vitamin C deficiency affects the vascular integrity of mice unable to synthesize ascorbic acid, with potentially profound effects on the pathogenesis of vascular diseases. Breeding the vitamin C-dependent mice with mice carrying defined genetic mutations will provide numerous opportunities for systematic studies of the role of antioxidants in health and disease.  (+info)

Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. (4/213)

BACKGROUND: Lack of reliable dietary data has hampered the ability to effectively distinguish between effects of smoking and diet on plasma antioxidant status. As confirmed by analyses of comprehensive food-frequency questionnaires, the total dietary intakes of fruit and vegetables and of dietary antioxidants were not significantly different between the study groups in the present study, thereby enabling isolation of the effect of smoking. OBJECTIVE: Our objective was to investigate the effect of smoking on plasma antioxidant status by measuring ascorbic acid, alpha-tocopherol, gamma-tocopherol, beta-carotene, and lycopene, and subsequently, to test the effect of a 3-mo dietary supplementation with a moderate-dose vitamin cocktail. DESIGN: In a double-blind, placebo-controlled design, the effect of a vitamin cocktail containing 272 mg vitamin C, 31 mg all-rac-alpha-tocopheryl acetate, and 400 microg folic acid on plasma antioxidants was determined in a population of smokers (n = 37) and nonsmokers (n = 38). The population was selected for a low intake of fruit and vegetables and recruited from the San Francisco Bay area. RESULTS: Only ascorbic acid was significantly depleted by smoking per se (P < 0.01). After the 3-mo supplementation period, ascorbic acid was efficiently repleted in smokers (P < 0.001). Plasma alpha-tocopherol and the ratio of alpha- to gamma-tocopherol increased significantly in both supplemented groups (P < 0.05). CONCLUSIONS: Our data suggest that previous reports of lower concentrations of plasma vitamin E and carotenoids in smokers than in nonsmokers may primarily have been caused by differences in dietary habits between study groups. Plasma ascorbic acid was depleted by smoking and repleted by moderate supplementation.  (+info)

Plasma vitamin C and food choice in the third Glasgow MONICA population survey. (5/213)

STUDY OBJECTIVE: To determine the contribution of different foods to the estimated intakes of vitamin C among those differing in plasma vitamin C levels, and thereby inform dietary strategies for correcting possible deficiency. DESIGN: Cross sectional random population survey. SETTING: North Glasgow, Scotland, 1992. PARTICIPANTS: 632 men and 635 women, aged 25 to 74 years, not taking vitamin supplements, who participated in the third MONICA study (population survey monitoring trends and determinants of cardiovascular disease). MEASUREMENTS AND MAIN RESULTS: Dietary and sociodemographic information was collected using a food frequency and lifestyle questionnaire. Plasma vitamin C was measured in non-fasted venous blood samples and subjects categorised by cut points of 11.4 and 22.7 micromol/l as being of low, marginal or optimal vitamin C status. Food sources of dietary vitamin C were identified for subjects in these categories. Plasma vitamin C concentrations were compared among groups classified according to intake of key foods. More men (26%) than women (14%) were in the low category for vitamin C status; as were a higher percentage of smokers and of those in the older age groups. Intake of vitamin C from potatoes and chips (fried potatoes) was uniform across categories; while the determinants of optimal versus low status were the intakes of citrus fruit, non-citrus fruit and fruit juice. Optimal status was achieved by a combined frequency of fruit, vegetables and/or fruit juice of three times a day or more except in older male smokers where a frequency greater than this was required even to reach a marginal plasma vitamin C level. CONCLUSION: Fruit, vegetables and/or fruit juice three or more times a day increases plasma vitamin C concentrations above the threshold for risk of deficiency.  (+info)

Vitamin C status and mortality in US adults. (6/213)

BACKGROUND: Low vitamin C status may increase the risk of mortality from cancer and cardiovascular disease. OBJECTIVE: The objective was to test whether an association existed between serum ascorbate concentrations and mortality and whether the association was modified by cigarette smoking status or sex. DESIGN: Serum ascorbate concentrations were measured in adults as part of the second National Health and Nutrition Examination Survey (1976-1980). Vital status was ascertained 12-16 y later. RESULTS: The relative risk (RR) of death, adjusted for potential confounders, was estimated by using Cox proportional hazards models. Men in the lowest (<28.4 micromol/L) compared with the highest (>/=73.8 micromol/L) serum ascorbate quartile had a 57% higher risk of dying from any cause (RR: 1.57; 95% CI: 1.21, 2.03) and a 62% higher risk of dying from cancer (RR: 1.62; 95% CI: 1.01, 2.59). In contrast, there was no increased risk among men in the middle 2 quartiles for these outcomes and no increased risk of cardiovascular disease mortality in any quartile. There was no association between serum ascorbate quartile and mortality among women. These findings were consistent when analyses were limited to nonsmokers or further to adults who never smoked, suggesting that the observed relations were not due to cigarette smoking. CONCLUSIONS: These data suggest that men with low serum ascorbate concentrations may have an increased risk of mortality, probably because of an increased risk of dying from cancer. In contrast, serum ascorbate concentrations were not related to mortality among women.  (+info)

Oral contraceptives and ascorbic acid. (7/213)

Plasma, leukocyte, and platelet ascorbic acid levels are decreased in women ingesting oral contraceptive steroids. Studies have shown that it is the estrogenic component of the oral contraceptive agents that is associated with the decresased ascorbic acid concentrations. Urinary excretion of ascorbic acid does not appear to be increased by the steroids. Although serum levels of copper are increased by estrogens and oral contraceptives, ascorbic acid catabolism does not appear to be increased (unpublished). Our preliminary data on tissue uptake of ascorbic acid suggest that changes in tissue distribution are one possible answer for the observed effects of the steroids on blood levels of ascorbic acid.  (+info)

Fractured neck of femur in black patients: a prospective study. (8/213)

We explored the role of iron overload, deficiency of vitamin C and alcohol abuse in the aetiology of cervical and intertrochanteric fractures of the neck of the femur as a result of minor trauma. We studied prospectively 72 patients (45 men, 27 women). Levels of serum iron markers, vitamin C and alcohol markers were measured. Consumption of alcohol was estimated using questionnaires. The findings were compared with those of an age- and gender-matched control group. The mean age of the men was 59.5 years and of the women 66.9 years, with a male predominance. In the men, iron overload, as shown by high levels of serum ferritin (p < 0.001) and deficiency of vitamin C (p < 0.03), as well as abuse of both Western and the traditional type of alcohol, appear to be important aetiological factors. In women, alcohol abuse was also common, but iron markers and levels of vitamin C did not differ significantly from the control group.  (+info)

Synonyms for Ascorbic acid deficiency in Free Thesaurus. Antonyms for Ascorbic acid deficiency. 23 synonyms for scurvy: contemptible, mean, bad, low, base, rotten, sorry, worthless, shabby, vile, low-down, pitiful, abject, despicable, dishonourable.... What are synonyms for Ascorbic acid deficiency?
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Vitamin C is one of the most important nutrients that the human body needs. Here we tell you all you need know about Vitamin C deficiency and why you should prevent it.
Cham B.E., Roeser H.P. and Nikles A.C. (1990) Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea pigs. Biochemical Journal, 267 2: 535-537. ...
Latest urology and nephrology news, research and treatment articles for urologists and nephrologists to stay updated. Clinical reviews on renal and urology treatments.
Although vitamin C deficiency and scurvy are generally considered as pure nutritional disorders, only a minority of the vitamin C concentration is determined by food intake. In the presence of transit
Extended blood tests and other tests have shown that those patients who had a lack of vitamin C also had higher levels of hsCRP, a protein that increases chances of inflammations and heart problems.. A year later, the participants health condition was evaluated again. It turned out that 29 per cent of the participants (61 individual) suffered from various cardiac events, starting from visiting emergency department to treat cardiac problems and ending up with death. The tests and analysis helped the scientists come to a conclusion that such factor as vitamin C deficiency associated with increased levels of hsCRP protein in the blood is linked to higher risks of having cardiovascular problems.. One of the study leaders, Eun Kyeung Song, assistant professor in nursing, College of Medicine, University of Ulsan, commented on the findings of his colleagues as the following: We found that adequate intake of vitamin C was associated with longer survival in patients with heart failure. He said that ...
A preliminary study that will be presented at the American Academy of Neurology meeting in April-May 2014 suggests that being deficient in Vitamin C raises your risk for a stroke. The lead researcher of the study, Dr. Stéphane Vannier, M.D., of Pontchaillou University Hospital in France, said that the research pointed to Vitamin C deficiency…
If PKD patients experience these symptoms, such as pale look, bleeding gums, poor appetite and fatigue, it may indicate they are suffering from vitamin C deficiency. Read on and you can find causes and solutions of these symptoms. Cause of
Like us, guinea pigs cant make vitamin C, but must obtain it from their diet. This makes them a good model for examining the effects of vitamin C deficiency.. In a recent study looking specifically at the effects of prenatal vitamin C deficiency, 80 pregnant guinea pigs were fed a diet that was either high or low in vitamin C. Subsequently, 157 of the newborn pups were randomly allocated to either a low or high vitamin C diet (after weaning), creating four conditions: high/high (controls); high/low (postnatal depletion); low/high (postnatal repletion); low/low (pre/postnatal deficiency). Only males experienced the high/low condition (postnatal depletion).. Only the postnatal depletion group showed any effect on body weight; no group showed an effect on brain weight.. Nevertheless, although the brain as a whole grew normally, those who had experienced a prenatal vitamin C deficiency showed a significantly smaller hippocampus (about 10-15% smaller). This reduction was not reversed by later ...
A recent study published in the American Journal of Epidemiology has found that one in seven young adults in Canada has a vitamin C deficiency. The study included 979 nonsmoking men and women between the ages of 20 and 29 years, who participated in the Toronto Nutrigenomics and Health Study from 2004 to 2008. The researchers used a comprehensive questionnaire in which participants were asked to assess their food intake over the previous month. From the responses, a total daily vitamin C intake was calculated for each person. Then the researchers measured the participants height, weight, waist circumference and body mass index and blood tests confirmed their vitamin C, glucose, inflammation, cholesterol and insulin levels. The results revealed that one in seven young Canadian adults has a vitamin C deficiency and that one in three has less than optimal levels of vitamin C. The findings also suggested that young adults with a vitamin C deficiency have significantly higher waist circumference, ...
Malaria is one of the most important tropical infectious diseases. Despite the fact that it is a completely preventable disease, a staggering 3.4 billion people continues to be at risk of the disease globally with 1.2 billion people at high risk particularly in high endemic and predominantly developing countries. In 2012, malaria was responsible for the death of approximately 482,000 under-five children. In Nigeria, Plasmodium falciparum malaria is responsible for around 60% of the out-patient visits to health facilities, 30% of childhood death, 25% of death in children under one year and 11% of maternal deaths. This study was carried out to determine the effect of Plasmodium falciparum parasitaemia on the serum ascorbic acid level of 60 malaria parasitized children of African descent aged 6 month-5 years visiting the children emergency unit and paediatric unit of Sokoto State Specialist Hospital in Sokoto, North Western, Nigeria. Controls included 30 non-parasitized children. Serum vitamin C ...
Vitamin C is a water-soluble vitamin and is not stored in the body in large quantities for prolonged periods of time. Since the human body cannot synthesize it, dietary intake of vitamin C on a regular basis is therefore necessary. Excess vitamin C is excreted in the urine thereby ensuring that the body has a total pool of about 1,500 milligrams (mg). Scurvy arises when a persons diet is deficient of vitamin C for about 3 months and the total body pool of vitamin C declines to levels below 350 mg.. The signs and symptoms associated with scurvy are largely due to the impaired synthesis of collagen. It is essentially the cement between cells that gives various tissues its firmness and strength. Weakening of these tissues, like the capillaries, leads to bleeding (hemorrhage), brittle bones and in children the normal growth of bone is affected. Iron absorption, immune function, the breakdown of cholesterol and formation of neurotransmitters are affected in scurvy thereby contributing to the ...
Free, official information about 2011 (and also 2012-2015) ICD-9-CM diagnosis code 267, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
Foxp3 stability of vitamin C-treated induced-regulatory T cells (V-iTregs) is superior to that of conventional iTregs (C-iTregs). However, the role of V-iTregs in allograft rejection under vitamin C-deficient conditions, such as those seen in humans, remains unclear. We aimed to elucidate the role of vitamin C treatment on generation and maintenance of iTregs from gulo knockout (Gulo-KO) mice as well as wild type (WT) mice, and in vitro and in vivo suppressive effects of V-iTregs on heart allograft rejection in either Gulo-KO or WT recipient mice. Conversion efficiency of iTregs was similar between C- and V-iTregs in both WT and Gulo-KO mice. V-iTregs from WT or Gulo-KO mice showed better in vitro Foxp3 stability than C-iTregs, although there was no difference between WT V-iTregs and Gulo-KO V-iTregs. Furthermore, V-iTregs from WT or Gulo-KO mice suppressed in vitro T cell proliferation better than C-iTregs. Heterotrophic heart transplantation from BALB/c mice to WT or vitamin C-deficient ...
It turns out that scurvy and vitamin C deficiency is still around these days. Scurvy is a disease resulting from a lack of vitamin C. Most animals can synthesize vitamin C, but not humans. We must eat foods containing vitamin C to get the vitamin. Vitamin C deficiency results in defective formation of collagen and connective tissues (in our bones, skin, tendons, muscles), and symptoms may include weakness, feeling tired, curly hair, sore arms and legs, bruising, bleeding gums, and impaired wound healing.. A recent small Australian study looked at diabetic persons with chronic foot wounds (foot ulcers that didnt heal after several months). Their vitamin C levels were tested and if found to be low, then they were given vitamin C supplements of 500 or 1000 mg daily, and the result was that within 2 to 3 weeks the wounds were healed. The one person with a zinc deficiency was given 50 mg daily of zinc supplement and that wound also promptly healed.. Treatment of scurvy is by taking vitamin C ...
Background. Vitamin C is associated with lower levels of high-sensitivity C-reactive protein (hsCRP), an inflammatory biomarker that predicts cardiovascular disease. However, whether low vitamin C intake is associated with hsCRP and cardiac event-free survival in patients with heart failure (HF) has not been examined.. Purpose. We hypothesized that patients with low vitamin C intake would have higher risk for elevated hsCRP and cardiac events than those with adequate intake of vitamin C.. Method. A total of 212 patients with HF (age 61±12 years, 34% female, 45% NYHA class III/IV) provided blood to measure serum hsCRP and were divided into 2 groups using 3mg/l of hsCRP as a cut-point. Patients completed a 4-day food diary verified with a registered dietitian. Nutrition Data System software program was used to determine intake of vitamin C. Adequacy of vitamin C intake was determined using formulas from the Institute of Medicine. Patients were followed for 1 year to determine time to first event ...
If theres one vitamin most people think they understand, it is vitamin C. This vitamin - also known as ascorbic acid - is present in many fruits and vegetables, and well known for its antioxidant properties and immune-enhancing powers. It is also responsible for aiding in the formation of connective tissue such as the skin, bones, and blood vessels. It also happens to be an essential component of health that the body is incapable of manufacturing on its own. As a result, it is critical that the human diet contain adequate sources of this nutrient.. As part of its grand mission in the body, this vitamin regenerates tissue, protects against many ailments like the cold and heart disease, helps to avoid scurvy, reduce bad cholesterol, and combat free radicals that can damage cellular integrity. It also aids in the bodys ability to absorb iron, and can delay the onset of cataracts.. Its effects on fatigue are well-documented. Though it can take several weeks of lowered vitamin C levels to produce ...
Neurological Benefits. The neurological benefits of vitamin C are profound and well-researched. This substance stimulates the production of a variety of enzymes involved in cognition. While the brain naturally produces these enzymes, it fails to produce them if you have a vitamin C deficiency.. As an antioxidant, vitamin C protects brain cells from the harmful effects of excessive stimulation. Oxidative stress leads to cell death, and vitamin C protects against oxidative stress in animal models.. Research has found that potassium channels play a role in depression. Vitamin C blocks potassium channels, which has antidepressive effects. A longitudinal study found that people who consumed adequate amounts of vitamin C were less likely to develop dementia. Since vitamin C is an antioxidant, it may also reduce the risk of Alzheimers disease.. Cardiovascular Benefits. Like other antioxidants, vitamin C appears to improve blood flow. Vitamin C deficiency increases your risk of atherosclerosis, so ...
Its wisdom thats been passed down through generations: Vitamin C, also known as ascorbic acid, can help prevent colds. Today, however. vitamin C is gaining in reputation as an amazing anti-ageing ingredient in advanced skincare formulations.. But in supplement form, its equally potent as a defender against hair loss ― and for one of the same reasons: collagen.. Collagen: Vitamin C is one of the most effective ways to boost your production of collagen, an antioxidant and protein that is equally important to a full, healthy head of hair it as it is to smooth, firm skin.. In the 1700s, it was discovered that citrus fruits could help prevent scurvy. It wasnt known why at the time, but the magic ingredient was eventually identified as vitamin C. Scurvy is actually caused by a vitamin C deficiency that disrupts the bodys ability to manufacture collagen and connective tissues in the skin.. Hair loss is a proven sign of vitamin C deficiency. Supplementing with vitamin C supports the production of ...
Vitamin C is one of the stars of skincare. Vitamin C is needed to make collagen that strengthens skin, muscles, and blood vessels and to ensure proper wound healing. Severe injury issues to increase vitamin C demands and vitamin c deficiency cause delayed healing.. Preliminary humans studies recommend that vitamin C supplementation in non-deficient people can speed healing of different varieties of wounds and trauma, including operation, minor scratches, herniated intervertebral discs, and skin ulcers. ...
When we look at the picture we are immediately drawn to the skin abnormality which is diffuse, purplish and irregular. It is in fact some mild bruising rather than a melanoma, although the latter is indeed a good thought. However, this is in part, a pseudo- red herring. It draws you away from the significant abnormality which is coiling of the hairs. Such a change is consistent with vitamin C deficiency (scurvy). One could indeed argue that the bruising is also caused by a vitamin C deficiency although there is not the typical peri-follicular hemorrhage that one sometimes sees in this condition ...
Obesity and the subsequent reprogramming of the white adipose tissue are linked to human disease-complexes including metabolic syndrome and concurrent non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). The dietary imposed dyslipidemia promotes redox imbalance by the generation of excess levels of reactive oxygen species and induces adipocyte dysfunction and reprogramming, leading to a low grade systemic inflammation and ectopic lipid deposition, e.g., in the liver, hereby promoting a vicious circle in which dietary factors initiate a metabolic change that further exacerbates the negative consequences of an adverse life-style. Large epidemiological studies and findings from controlled in vivo animal studies have provided evidence supporting an association between poor vitamin C (VitC) status and propagation of life-style associated diseases. In addition, overweight per se has been shown to result in reduced plasma VitC, and the distribution of body fat in obesity ...
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The observational study began on 01 November 2012 and is scheduled for a period of 10 years continued (until 01 November 2022). The duration of the observational study for each patient is not fixed corresponding to the character of a non-interventional study. According to the underlying disease, characterized either acute or chronic, there are 2 and 3 observations within the treatment period, respectively. Documentation comprises the course of the underlying diseases (by tracking of general and diseases-specific symptoms), drug compatibility (by ADR assessment), concomitant medication or other treatment, health economic data, details of treatment regimen and standard epidemiological data ...
Ascorbic acid is an essential nutrient involved in collagen formation, and its deficiency is associated with abnormal bone development. To examine the relation of ascorbic acid to bone mineral density and the prevalence of self-reported fractures, the authors analyzed data collected from 13,080 adults enrolled in the Third National Health and Nutrition Examination Survey (NHANES III) during 1988-1994. Because they identified three-way interactions among smoking, history of estrogen use, and dietary and serum ascorbic acid in postmenopausal women, they analyzed these relations stratified by smoking and estrogen use. Dietary ascorbic acid intake was independently associated with bone mineral density among premenopausal women (p = 0.002). Among men, serum ascorbic acid was associated in a nonlinear fashion with bone mineral density (p , 0.05), and dietary ascorbic acid intake was associated in a nonlinear fashion with self-reported fracture (p = 0.05). Among postmenopausal women without a history ...
Vitamin C deficiency causes scurvy and can compromise many bodily functions. Vitamin C is involved in mast cells and other immune cells, such as NK cells, and differ..
I was watching an episode of The Backyardigans the other day with my two five year olds and the characters started singing a song about What Do You Do with a Scurvy Pirate? The answer was that you make them walk the plank. So I got to thinking about it...isnt scurvy just a disease that was common on pirate ships and other ships long ago? Was it a reason to walk the plank? Are they using the term on the show to mean something different...like a bad pirate (as if any pirate was a good pirate by definition)? I think the song implied the later...like scurvy = treacherous, diabolical, dangerous, etc. So I looked up scurvy and it actually is caused by a vitamin C deficiency and it was prevalent on ships in the 1800s because the fruit the sailors would take with them would perish before their long voyage was over resulting in vitamin C deficiencies which often was fatal at that time. Fatalities from it are, of course, very rare now. And certainly, scurvy was never a reason to force someone to walk ...
Metabolic syndrome (MetS) is a constellation of cardiometabolic risk factors, which together predict increased risk of more serious chronic diseases. We propose that one consequence of dietary overnutrition is increased abundance of Gram-negative bacteria in the gut that cause increased inflammation, impaired gut function, and endotoxemia that further dysregulate the already compromised antioxidant vitamin status in MetS. This discussion is timely because healthy individuals are no longer the societal norm and specialized dietary requirements are needed for the growing prevalence of MetS. Further, these lines of evidence provide the foundational basis for investigation that poor vitamin C status promotes endotoxemia, leading to metabolic dysfunction that impairs vitamin E trafficking through a mechanism involving the gut-liver axis. This report will establish a critical need for translational research aimed at validating therapeutic approaches to manage endotoxemia-an early, but ...
The premise behind the Vitamin C theory of heart disease is this: chronic scurvy. Weve all heard of sailors of long ago who brought citrus fruits along with them on their long sea voyages to avoid scurvy. Scurvy is a disease resulting from a vitamin c deficiency. The human body is unable to synthesize its own supply of vitamin c, so it needs to be supplemented through vitamin c-rich foods, and/or a vitamin supplement. Symptoms of scurvy include bleeding gums, fatigue, irritability, leg pain, easily-bruised skin, wounds that fail to heal, and more. These symptoms usually occur about 3 months after the person has been lacking enough vitamin c. Vitamin c is present in fresh fruits and vegetables, and in some meats. However, when foods are heavily processed and cooked, they lose most of this vitamin. So if your diet lacks fresh produce, you are setting yourself up for what is known as chronic scurvy. Vitamin c (aka L-ascorbic acid) is necessary for collagen production and iron absorption. It also ...
What causes your arteries to get blocked?. Atherosclerosis is a disease defined as hardening or thickening of the arteries. What allows the blood to keep flowing is the thin layer of endothelial cells.. However, there are a few factors that damage endothelial cells (and form atherosclerotic lesion) including free radicals, antioxidant deficiency, increased homocysteine levels, and vitamin C deficiency.. Plaque will accumulate when various substances are unable to migrate out of the atherosclerotic lesion. These substances include toxic metals, cellular waste, calcium, LDL cholesterol, triglycerides, and blood clotting materials.. Although the real cause of clogged arteries remains unclear, mounting evidence suggests that atherosclerosis is a complex condition which might start in childhood and develop as you get older. Factors like diabetes, insulin resistance, smoking, and hypertension are known to be damaging to the arteries.. 10 natural foods to unclog your arteries. Your doctor may prescribe ...
Scurvy is a disease now known to be caused by a vitamin C deficiency, but in Linds day, the concept of vitamins was unknown. Vitamin C is necessary for the maintenance of healthy connective tissue. In 1740 the catastrophic result of Ansons circumnavigation attracted much attention in Europe; out of 1900 men, 1400 had died, most of them allegedly from having contracted scurvy. According to Lind, scurvy caused more deaths in the British fleets than French and Spanish arms.[6] Since antiquity in various parts of the world, and since the 17th century in England, it had been known that citrus fruit had an antiscorbutic effect, when John Woodall (1570-1643), an English military surgeon of the British East India Company recommended them[7] but their use did not become widespread. Although Lind was not the first to suggest citrus fruit as a cure for scurvy, he was the first to study their effect by a systematic experiment in 1747.[8] It ranks as one of the first reported, controlled, clinical ...
Scurvy is a disease caused by vitamin C deficiency that was once common among sailors and pirates who were at sea longer than fruits and vegetables could be stored. Symptoms include malaise and lethargy, followed by spotty skin, spongy gums (ew!!), and bleeding from mucous membranes. If youre suffering from spongy gums, Brazos cant do much for you, but if your Spring Break
Description: Vitamin C must be acquired from dietary sources, as humans are unable to synthesize it. While a severe deficiency of vitamin C ultimately leads to scurvy, variations in vitamin C levels have also been associated with a wide range of chronic complex diseases, such as atherosclerosis, type 2 diabetes and cancer. A healthy diet will typically provide sufficient vitamin C, though people with problems absorbing vitamin C or people with a genetic variant may have increased risk of vitamin C deficiency.. ...
1. Lykkesfeldt J, Christen S, Wallock LM, et al. Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. Am J Clin Nutr. 2000;71:530-536. 2. Hercberg S, Preziosi P, Galan P, et al. Vitamin status of a healthy French population: Dietary intakes and biochemical markers. Int J Vitam Nutr Res. 1994;64:220-232. 3. Lowik MR, Wedel M, Kistemaker C, et al. Assessment of the adequacy of vitamin C intake in the Netherlands [abstract]. J Am Coll Nutr. 1991;10:544. 4. US Department of Agriculture. National Food Consumption Survey. 1985. 5. Baker B. Vitamin C deficiency common in hospitalized. Fam Pract News. March 1995:25. 6. Taylor CA, Hampl JS, Johnston CS. Low intakes of vegetables and fruits, especially citrus fruits, lead to inadequate vitamin C intakes among adults. Eur J Clin Nutr. 2000;54:573-578. 7. Taylor CA, Hampl JS, Johnston CS. Low intakes of vegetables and fruits, especially citrus fruits, lead ...
From zoe 9 years ago Add yours; Pick If you are diabetic you will love this recipe. Diabetes On Quizlet 2 Facts Type people with Type 1 diabetes always require insulin injections in Diabetes On Quizlet 2 Facts Type order to control blood sugar readings because they make little or no insulin. Comentarios No tiene cuenta? Diabetes Cause Frequent Urination Treatment Diabetes & Alternative Diabetes Treatment Diabetes Cause Frequent Urination Diabetic Nerve Pain Evidence grade Condition to which grade level applies; A: Vitamin C deficiency (scurvy) Scurvy is caused by a lack of vitamin C in the diet. Scribd is the worlds largest social reading and Cure For Diabetes 1 In 2016 Diabetic Sweetener :: Diabetes Type 1 Stomach Pain Article Diabetes Type 1 Stomach Pain; Diabetes is a risk diabetic friendly coconut cookies link stress between factor for pancreatic cancer but Diabetes On Quizlet 2 Facts Type its association with survival from pancreatic cancer is poorly understood. What to Do In a Mental ...
Copper and vitamin C are direct antagonists. This means that they oppose each other in the body. This is one reason many people feel better taking a lot of vitamin C. Copper tends to oxidize and destroy vitamin C in the body. Meanwhile, vitamin C chelates or removes copper from the body. This requires a dose of vitamin C of at least about 500 mg daily, far higher than the minimum daily requirement of about 60 mg. Many readers know that vitamin C is critical for connective tissues. One of the prominent symptoms of scurvy, or vitamin C deficiency, is bleeding, such as bleeding gums. This is due to connective tissue weakness. ...
One of the most common questions people ask when they first hear about the all-meat diet is, Where do you get your vitamin C? Since a vitamin C deficiency leads to scurvy, a very serious and ultimately lethal illness, it is a perfectly understandable and legitimate line of inquiry. None of the long term practitioners of…
One of the most common questions people ask when they first hear about the all-meat diet is, Where do you get your vitamin C? Since a vitamin C deficiency leads to scurvy, a very serious and ultimately lethal illness, it is a perfectly understandable and legitimate line of inquiry. None of the long term practitioners of…
Signs of vitamin C deficiency can appear within one month of little to no vitamin C intake. Your risk of developing periodontal disease, a severe form of...
msn.com A new study explores added advantages of Vitamin C consumption and advocates that adding it to our daily diet could work wonders in healing bleeding gums. If your gums bleed, make sure you are brushing and flossing twice a day because it could be a sign of gingivitis, an early stage of periodontal disease.  However, you should also check your intake of vitamin C, as per the study. The findings of the study led by the University of Washington, were published in the journal. When you see your gums bleed, the first thing you should think about is not, I should brush more. You should try to figure out why your gums are bleeding. And vitamin C deficiency is one possible reason, said the studys lead author Philippe Hujoel, a practicing dentist and professor of oral health sciences in the UW School of Dentistry. Hujoels study analyzed published studies of 15 clinical trials in six countries, involving 1,140 predominantly healthy participants, and data from 8,210 U.S. residents surveyed in the
Fermenting foods dates back thousands and thousands of years. There are even cave drawings dating back 12,000 years of men obtaining honey from hives and using it to make mead, a honey wine. More recently, during the 19th century, the English explorer, Captain James Cook, had sixty barrels of sauerkraut hauled aboard his ship for his second trip around the world. The kraut lasted for 27 months and fed the crew well. Captain Cook was later recognized by the Royal Society for conquering scurvy, the disease that results from vitamin C deficiency, which had plagued many other sea crews (source). This is because lacto-fermented sauerkraut contains ample amounts of vitamin C. While the Captain got the glory, cultures all over the world had been eating these fermented foods for centuries; it was just part of their daily life, and still is, in many areas, today. The Koreans eat kimchi, cortido is popular in South America, miso, tempeh, and tamari are traditional Asian foods, kefir is a staple in Russia, ...
Taking megadoses of vitamin C may lead to kidney damage, diarrhea, iron overload and accelerated atherosclerosis (hardening of the arteries). It increases the risk of kidney stones in some people. If stopped abruptly, it may result in rebound scurvy (vitamin C deficiency). Doses between 2000 and 5000 mg per day may have anti-coagulant properties, making it difficult for people to stop bleeding ...
In dermatology, there are typical examples of disorders related to dietary factors. The pathogenic, links between nutritional factor(s) and skin disease may be different.. Nutrient deficiency and nutrient excess are the simplest causes of specific diet-related cutaneous changes: scurvy (vitamin C deficiency) and acrodermantis enteropathica (zinc deficiency) are examples of the first type, and caronenoderma (carotene excess) is an example of the second type. Genetic metabolic defects or enzyme deficiencies, although subtle, may pave the way for the onset of diet-related skin disorders, where a toxic effect is exerted by the dietary factor(s): alcohol intake is responsible for porphyria curanea tarda, and the ingestion of choline- and lecithin-containing foods is the cause of eccnine bromhidrosis, with the typical fishy odor that features trimethylaminuria. More often, an immune (and complex) mechanism is involved in the pathogenesis of strictly diet-dependent skin disorders, e.g. atopic ...
s to prevent the occurrence of scurvy (sore gums and teeth) and increase body resistance to infection. Astymin C corrects vitamin C deficiency and supplements essential Amino acids during infancy. Astymin C ensures proper growth and development and strengthens body resistance in infants. Astymin C has a pleasant taste and flavor which ensures better patient compliance.. ...
Prof: So patient presents with a splinter in his finger. He has a Y chromosome, so he left it in there.... Prof: So what kind of people would you typically see Vitamin C deficiency, aka scurvy? Genius: Pirates? Prof: So why do we only take a baby aspirin instead of an adult aspirin if we…
Ask your doctor if you think any of these factors have led you to develop a vitamin C deficiency. If so, vitamin C shot therapy could be the best solution.
EDIT: sorry title is supposed to say 20mg on top of red pepper. Is it too much? Sorry for typo so I think I read guinea pigs just need 30mg of C to stave off ill health from vitamin C deficiency. Today I served her 28 grams of red pepper which has 35 mg of C. The vet gave me though at our ...
Vitamin C deficiency has been assoc with frequency and duration of colds, along with immune system defects, which are of concern for children with Down Syndrome
USD 0.88 - Indonesia Bali, Limcee® chewable tablets contain Vitamin C (Ascorbic Acid), which is an essential nutrient for normal growth, development, and overall health. Limcee® chewable tablets help to restore the Vitamin C deficiency, helping to increase the resistance to stress, infections and to promote immune system functioning. - Pharm Trends
Ascorbic Acid Deficiency 7% * Niacin 7% * Pica 7% * Statistical Factor Analysis 7% ...
Ascorbic Acid Deficiency--Newfoundland and Labrador; Diabetes Mellitus--Newfoundland and Labrador; Vitamin E Deficiency-- ... Diabetes--Nutritional aspects--Newfoundland and Labrador; Vitamin C deficiency--Newfoundland and Labrador; Vitamin E deficiency ...
Active substance: Ascorbic acid 100 mg per tablet. Indications: All forms of ascorbic acid deficiency, such as for strong ... Active substance: Ascorbic acid 100 mg per tablet. Indications: All forms of ascorbic acid deficiency, such as for strong ... All forms of ascorbic acid deficiency, such as • for strong physical stress, • during pregnancy and breastfeeding, • for cold ... 1 to 2 tablets a day are enough to prevent ascorbic acid deficiencies;At the beginning of treatment 2 to 3 tablets should be ...
Ascorbic acid and vitamin deficiencies rutoside. In the complex treatment of varicose veins, venous disorders and skin ulcers, ... 1 tablet contains: 50.0 mg of ascorbic acid and rutoside relative to anhydrous substance 50.0 mg.. Product form:. Tablets. 10, ... Ascorbic acid is involved in the regulation of redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration ...
Ascorbic acid deficiency and hypertrophic osteodystrophy in the dog: a rebuttal. Cornell Vet. 1979 Oct;69(4):384-401. ...
Natural L-Ascorbic acid 10% Super Serum: Pure Light Serum 10 contains 10% pure vitamin C to neutralize free radicals that ... Wound healing a new perspective with particular reference to ascorbic acid deficiency. Annals of surgery, 144(3), 304. ... Vitamin C or ascorbic acid (INCI name: Ascorbic Acid) is a vitamin naturally present in human skin (Shindo et al., 1994). ... Natural L-Ascorbic acid 10% Super Serum:. Pure Light Serum 10 contains 10% pure vitamin C to neutralize free radicals that ...
Scurvy is caused by a deficiency of vitamin C (ascorbic acid) in the diet. In fact, its discovery resulted from the first ever ... This occurs due to the solubility of ascorbic acid in water meaning that it dissolves easily out of vegetables, such as ... of its ascorbic acid concentration during cooking. The heat of the boiling water also causes the vitamin to degrade, further ...
Treating Scurvy Problem Scurvy takes place when the person is affected with ascorbic acid deficiency. It is a type of ailment ... The main reason for this ailment is insufficient ascorbic acid or vit c, contained in fresh vegetables and fruit mainly citrus ...
Uses of Ascorbic Acid Chewable Tablets: It is used to treat or prevent vitamin C deficiency. Some of the dosage forms listed on ... I-SHOT (Vitamin C + zinc ) also known as ascorbic acid . Offer. Iron - Folic Acid With Zinc Capsules Send Inquiry . Customers ... also known as ascorbic,! C + Zinc ) also known as ascorbic Acid, Vitamin C - 3 Supply... + £7.00 P & P: + £7.00 P & P: + £7.00 ... ASCORBIC ACID (a SKOR bik AS id) is a naturally occurring form of vitamin C. It is used to treat or prevent low levels of ...
As we now know, scurvy is a disease caused by deficiency of Vitamin C - ascorbic acid. (The name itself is a contraction of " ... While one particular acid could have cured it, not all acids are equal. Thus, advocating for vinegar, sour wine, or - I am not ... Different citrus fruits have differing amounts of ascorbic acid - as do other fresh fruits and vegetables. And this differs too ... It was this idea of acid and alkaline balance. Because scurvy was (in this theory) either acid or alkaline, depending on the ...
Experts agree that people who have ascorbic acid deficiency have greater rates of gums and teeth. Ascorbic Acid may assist in ... A few of the dietary supplements suggested to avoid gums and teeth from developing are folic acids for rinsing. Ascorbic Acid, ... If you suffer from acid reflux, GERD or heartburn, the acids within your abdomen could make their way the tonsils and into your ... Strawberries contain malic acid, which can whiten your teeth. However, the flip side is that it can also erode the enamel. ...
Scurvy is a disease, which is caused by a long-term deficiency of vitamin C (ascorbic acid). Scurvy is determined as a serum ... Vitamin C (ascorbic acid) is undoubtedly a well-known water-soluble vitamin to all of us, but do we know how important this ... OMEGA-3 FATTY ACIDS - The Amazing 23 Health Benefits of Omega-3 Fatty Acids Based on Science ... OMEGA-3 FATTY ACIDS - The Amazing 23 Health Benefits of Omega-3 Fatty Acids Based on Science ...
There is always a big argument in the natural health world on whether whole food vitamin C or ascorbic acid is best. Well, ... Also, Ascorbic acid actually can cause copper deficiency, while whole food vitamin C supports proper copper balance. Since I am ... on the label are really ascorbic acid which is just the shell of the vitamin C complex. In whole food C, ascorbic acid is just ... Ascorbic acid is NOT Real Vitamin C. Whole Food Vitamin C is yet another nutrient that we are lied to about. 90% of the ...
Clinical manifestations of ascorbic acid deficiency in man. Am J Clin Nutr. 1971;24(4):432-43.. ... Clinical manifestations of ascorbic acid deficiency in man. Am J Clin Nutr. 1971;24(4):432-43.. ... Nutrient deficiencies arent the only risk. Reading about all the successful reports of massive weight loss from prolonged ... Nutrient deficiencies arent the only risk. Reading about all the successful reports of massive weight loss from prolonged ...
Ascorbic Acid Vitamin C Holland And Barrett B12 Alcoholics Deficiency how to Overcome Drug Cravings. Poti alege cadoul tau ... Absorb folic acid more slowly to critically stringent quality assurance non-animal form Vitamin. End of the images gallery ... Pregnancy can make you absorb folic acid more slowly. The views expressed below are the opinion of Holland & Barrett customers ...
Scurvy, a deficiency of vitamin C (ascorbic acid), occurs after several months without fresh fruits and vegetables in the diet ...
As for lactic acid? L-ascorbic acid is the naturally-occurring form of vitamin C, while niacinamide is the -amide form of ... As for lactic acid? L-ascorbic acid is the naturally-occurring form of vitamin C, while niacinamide is the -amide form of ... My opinion is that you CAN mix niacinamide and ascorbic acid! The chances of niacinamide and vitamin C interacting with each ... My opinion is that you CAN mix niacinamide and ascorbic acid! The chances of niacinamide and vitamin C interacting with each ...
A disease caused by prolonged severe dietary deficiency of ascorbic acid , in which the breakdown of intercellular cement ... Fibric acid derivatives may increase cholesterol excretion into bile, leading to cholelithiasis, and ezetimibe vytorin adverse ...
... pioneering scientific researchers established a significant correlation between a single nutritional deficiency (ascorbic acid ... Since ascorbate deficiency is the common cause of human CVD, ascorbate resupplementation is the universal treatment for this ...
Provides antioxidants and Helps to prevent deficiency. Ingredients: Vitamin C (ascorbic acid) 150 mg Calcium... ... Helps to prevent niacin deficiency. Ingredients: Vitamin C (ascorbic acid) 150 mg Calcium (calcium citrate,... ... Ingredients Vitamin C (ascorbic acid, magnesium ascorbate) 100 mg Niacinamide 20 mg Calcium (calcium... ... 40 mgPantothenic acid (vitamin B5)........ 5 mgRiboflavin (vitamin B2) (riboflavin-5-sodium... ...
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Sato Y, Arai KY, Nishiyama T, Nomura Y, Kishimoto Y, Aizawa S, Maruyama N, Ishigami A. Ascorbic acid deficiency leads to ... Vitamin C yang didapat dari diet akan dirubah menjadi L-ascorbic acid dan L-dehydroascorbic. Distribusi L-ascorbic acid ... Topical L-Ascorbic Acid: Percutaneous Absorption Studies. Dermatol Surg. 2001;27(2):137-40. 7. Nusgens BV, Humbert P, Rougier A ... Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs placebo ...
Ascorbic Acid Deficiency Activates Cell Death and Disease Resistance Responses in Arabidopsis1 Valeria Pavet, Enrique Olmos2, ... Swaroop, A and Gupta , A P and Sinha, Arun K (2005) Simultaneous determination of quercetin, rutin and coumaric acid in flowers ...
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Ascorbic Acid(500mg) mainly use for Prevention and treatment of scurvy, Scurvy, Vitamin deficiency.. and the side effects of ... Acid Ascorbic một hợp chất sáu carbon liên quan đến glucose. Read … Ascorbic Acid(500mg) Tablet contain ascorbic acid as ... Ascorbic acid is a weak sugar acid structurally related to glucose. Ascorbic Acid (vitamin C) is a nutritional supplement. 4.7 ... Cancel reply acid 500mg Tablet contains the active ingredients acid. Read … you need ascorbic acid 500mg acid, also known as ...
Scurvy is a deficiency that is caused by a lack of vitamin C (ascorbic acid) in a persons diet. Vitamin C is essential for the ...
Ascorbic Acid (Vitamin C) improves overall health, protects against immune. system deficiencies and even skin wrinkling. ... Is one of the sulfur-containing amino acids. It acts as a. lipotropic agent to prevent excess fat buildup in the liver and the ... L-Carnitine a naturally occurring amino acid which plays a vital role in the. metabolism of fat. It functions as a transporter ... of fatty acids into the. mitochondria, the metabolic furnace of the cell. ...
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  • Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. (harvard.edu)
  • less than 0.1mg/L indicates severe deficiency and symptoms of scurvy are typically manifest). (renalandurologynews.com)
  • Ascorbic acid deficiency results in scurvy. (nih.gov)
  • Ascorbic acid is recommended for the prevention and treatment of scurvy. (nih.gov)
  • ascorbic acid, another name for vitamin C, literally means "without scurvy. (vitanetonline.com)
  • Deficiency of ascorbic acid in the diet results in scurvy and other less serious conditions. (intekom.com)
  • The history of the discovery of vitamin deficiencies progressed over centuries from observations that certain conditions - for example, scurvy - could be prevented or treated with certain foods having high content of a necessary vitamin , to the identification and description of specific molecules essential for life and health. (wikipedia.org)
  • Vitamin C was identified in the early twentieth century in the search for a substance, the deficiency of which would cause scurvy [ 1 , 2 ]. (mdpi.com)
  • True vitamin C deficiency is responsible for scurvy. (gurze.com)
  • The health benefits of vitamin C, also known as ascorbic acid, include the prevention and management of scurvy, common cold, and lead toxicity. (organicfacts.net)
  • Scurvy is caused by an insufficient intake or deficiency of ascorbic acid. (organicfacts.net)
  • Scurvy is a state of dietary deficiency of vitamin C (ascorbic acid). (medscape.com)
  • Although scurvy is uncommon, it still occurs and can affect adults and children who have chronic dietary vitamin C deficiency (see the image below). (medscape.com)
  • Plasma ascorbic acid level may help in establishing the diagnosis, but this level tends to reflect the recent dietary intake rather than the actual tissue levels of vitamin C. Signs of scurvy can occur with low-normal serum levels of vitamin C. (medscape.com)
  • deficiency produces scurvy and poor wound repair. (thefreedictionary.com)
  • A deficiency of ascorbic acid causes scurvy. (thefreedictionary.com)
  • Severe deficiency results in scurvy. (thefreedictionary.com)
  • Low levels of dietary ascorbic acid lead to the condition formerly known as scurvy. (3fatchicks.com)
  • Scurvy is the classic manifestation of severe ascorbic acid deficiency. (catalogs.com)
  • Scurvy is the name for a vitamin C deficiency. (medicalnewstoday.com)
  • Symptoms of scurvy result from severe vitamin C deficiency. (medicalnewstoday.com)
  • Scurvy happens when there is a lack of vitamin C, or ascorbic acid. (medicalnewstoday.com)
  • When the voyages lasted longer than the supply of fruits and vegetables, the sailors began to suffer from vitamin C deficiency, which led to scurvy. (webmd.com)
  • Now we know that scurvy is nothing more than vitamin C deficiency. (memorialhospitaljax.com)
  • Ascorbic acid is also used to prevent and treat scurvy (a disease that causes fatigue, gum swelling, joint pain, and poor wound healing from a lack of vitamin C in the body). (medlineplus.gov)
  • Severe deficiency of vitamin C causes scurvy. (news-medical.net)
  • Vitamin C (ascorbic acid) is a water soluble vitamin used to prevent and treat scurvy and acidify urine. (patientslikeme.com)
  • SCURVY , a disease of dietary ascorbic acid deficiency, is uncommon today. (worldwidescience.org)
  • Taking vitamin C by mouth or injecting as a shot prevents and treats vitamin C deficiency, including scurvy. (rxlist.com)
  • Scurvy is a deficiency disease caused by lack of vitamin C (ascorbic acid). (coolantarctica.com)
  • Scurvy related to vitamin C deficiency ravaged and plagued previous [Anartic[ expeditions, including those to the polar regions. (wheelessonline.com)
  • Scurvy - Prolonged deficiency of ascorbic acid, also known as vitamin C, in the human body causes scurvy. (4to40.com)
  • Scurvy is a disease resulting from a lack of vitamin C (ascorbic acid). (wikipedia.org)
  • Scurvy, including subclinical scurvy, is caused by a deficiency of dietary vitamin C since humans are unable to metabolically make this chemical. (wikipedia.org)
  • Scurvy is one of the accompanying diseases of malnutrition (other such micronutrient deficiencies are beriberi or pellagra ) and thus is still widespread in areas of the world depending on external food aid. (wikipedia.org)
  • The disease scurvy, traced to vitamin C (ascorbic acid) deficiency, results when defective collagen prevents the formation of strong connective tissue. (newworldencyclopedia.org)
  • People who don't get enough are at risk for short-term problems like fatigue and certain skin problems, but longer-term deficiencies can lead to more serious conditions like anemia and scurvy . (wisegeek.com)
  • Ascorbic acid (vitamin C), an essential vitamin, is commonly used in pharmacologic doses for the prevention of the common cold and to promote the healing of wounds. (annals.org)
  • Diabetics, patients prone to recurrent renal calculi, those undergoing stool occult blood tests and those on sodium restricted diets or anticoagulant therapy should not take excessive doses of ascorbic acid over an extended period of time. (nih.gov)
  • Assertions that massive doses of ascorbic acid prevent colds and influenza have not been borne out by carefully controlled experiments. (catalogs.com)
  • Vitamin C megadosage is a term describing the consumption or injection of vitamin C (ascorbic acid) in doses well beyond the current Recommended Dietary Allowance of 90 milligrams per day, and often well beyond the tolerable upper intake level of 2,000 milligrams per day. (wikipedia.org)
  • Do not stop using ascorbic acid suddenly after long-term use at high doses, or you could have "conditional" vitamin C deficiency. (wellspan.org)
  • Ascorbic acid was given in 25 mg. doses, 4 times daily, until the temperature returned to normal. (whale.to)
  • Kidney stones or other very bad kidney problems have rarely happened in people taking high doses of this medicine (ascorbic acid capsules and tablets) for a long time. (drugs.com)
  • While a vitamin C deficiency can lead to serious health problems, large doses of vitamin C may cause nausea and headaches. (wisegeek.com)
  • Periosteal elevation may also occur as a result of subperiosteal hemorrhage from capillary fragility as a direct result of ascorbic acid deficiency. (renalandurologynews.com)
  • Marginal deficiencies of thiamin, riboflavin, vitamin B-6 and vitamin C : prevalence and functional consequences in man / Eric Jan van der Beek. (who.int)
  • Riboflavin deficiency also causes anemia with red blood cells that are normal in size and hemoglobin content, but reduced in number. (wikipedia.org)
  • Effect of riboflavin,choline,pantothenic acid and vitamin A on the excretion of sodium in urine of rats. (nii.ac.jp)
  • Effect of single deficiency of vitamin A,thiamine,riboflavin or ascorbic acid on the dark adaptation. (nii.ac.jp)
  • Regarding the vitamin C deficiency, the investigators focus on the acquisition of data of the underlying diseases and the reduction of symptoms, that are related to oxidative stress and vitamin-C-deficiency. (clinicaltrials.gov)
  • As a result, ascorbic acid protects against oxidative stress and premature cell aging. (gurze.com)
  • Ascorbic acid combats arsenic-induced oxidative stress in mice liver. (biomedsearch.com)
  • Repeated injections of arsenic trioxide induced oxidative stress and hepatotoxicity in mice as revealed from elevated levels of glutamate oxaloacetate transaminases, glutamate pyruvate transaminases, acid and alkaline phosphatases, lipid peroxidation along with reduction of superoxide dismutase, catalase, reduced glutathione content, glutathione reductase and succinate dehydrogenase activities. (biomedsearch.com)
  • The Hp 2-2 polymers are less efficient inhibitors of hemoglobin-driven oxidative stress, leading to ascorbic acid depletion. (medscape.com)
  • Dogs hospitalised for ê72 hours had significantly greater plasma ascorbic acid concentrations on day 3 compared to days 1 and 2. (wiley.com)
  • There was no difference in plasma ascorbic acid concentrations between days 1 and 2 for dogs hospitalised for 36 to 72 hours. (wiley.com)
  • Plasma ascorbic acid concentrations were significantly greater for each day of sampling for the hospitalised dogs compared to the control dogs. (wiley.com)
  • Plasma ascorbic acid concentrations appear to increase during hospitalisation, and supplementation may not be indicated in dogs hospitalised in an intensive care unit. (wiley.com)
  • A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. (harvard.edu)
  • The serum protein or copper level did not indicate their dietary deficiency, while initial serum ascorbate level were low which rose by 60% on therapy. (whale.to)
  • Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency. (nih.gov)
  • There are no contraindications to the administration of ascorbic acid. (nih.gov)
  • The present study was, therefore, undertaken to see the effect of administration of ascorbic acid on hemoglobin and iron status of strictly vegetarian people. (whale.to)
  • Take ascorbic acid exactly as directed. (medlineplus.gov)
  • How should I take ascorbic acid? (wellspan.org)
  • Who should not take Ascorbic Acid? (webmd.com)
  • What do I need to tell my doctor BEFORE I take Ascorbic Acid Capsules and Tablets? (drugs.com)
  • What are some things I need to know or do while I take Ascorbic Acid Capsules and Tablets? (drugs.com)
  • Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency. (harvard.edu)
  • We measured some haematological and biochemical parameters to establish any correlation between serum ascorbic acid and iron and thus open study line on the need for co-supplementation of the two during antenatal visits to prevent iron-deficiency anaemia in pregnancy. (biomedres.info)
  • Relation of serum ascorbic acid to mortality among US adults. (thejcdp.com)
  • A controlled study has been made of the effect of ascorbic acid deficiency in guinea-pigs experimentally infected intracecally with Endamoeba histolytica trophozoites. (ajtmh.org)
  • The effect of ascorbic acid deficiency on brain catecholamines and monoamine oxidases. (bvsalud.org)
  • Effect of ascorbic acid,vitamin B and milk on the dark adaptation. (nii.ac.jp)
  • Effect of ascorbic acid deficiency on the permeability and collagen biosynthesis of oral mucosal epithelium. (thejcdp.com)
  • Reduced bactericidal activity in neutrophils from scorbutic animals and the effect of ascorbic acid on these target bacteria in vivo and in vitro. (thejcdp.com)
  • Effect of ascorbic acid deficiency on primary and reparative dentinogenesis in non-ascorbate-synthesizing ODS rats. (thejcdp.com)
  • Beneficial effects of ascorbic acid to treat lung fibrosis induced by paraquat. (bioportfolio.com)
  • What are the possible side effects of ascorbic acid? (wellspan.org)
  • What are some other side effects of Ascorbic Acid Capsules and Tablets? (drugs.com)
  • The effects of ascorbic acid deficiency on the teeth and periodontal tissues of guinea pigs. (thejcdp.com)
  • Effects of ascorbic acid and DL-alpha-tocopherol on human hepatoma cell proliferation and redifferentiation. (thejcdp.com)
  • Vitamin C also known as, ascorbic acid, L-ascorbic acid, dehydroascorbic acid, the antiscorbutic vitamin, L-xyloascorbic acid and L-threo-hex-2-uronic acidy-lactone, is a much talked about vitamin, with people claiming it as a cure-all for may diseases and problems - from cancer to the common cold. (best-home-remedies.com)
  • ascorbic acid (vitamin C) can be effective in managing solid tumor diseases. (bioportfolio.com)
  • ICD-10 Code range (E00-E89),Endocrine, nutritional and metabolic diseases, contains ICD-10 codes for Disorders of thyroid gland, Diabetes mellitus, Other disorders of glucose regulation and pancreatic internal secretion, Disorders of other endocrine glands, Intraoperative complications of endocrine system, Malnutrition, Other nutritional deficiencies. (aapc.com)
  • A plethora of papers have been published on this topic, but, although it is well known that a deficiency of vitamin C due to a low nutritional intake leads to a greater susceptibility to infections ( 5 ), the possibility of reducing the incidence of viral diseases in a well-nourished population through the use of dietary supplements based on vitamin C is not adequately supported in literature. (frontiersin.org)
  • l-ascorbic acid (L-AA, vitamin C) is an essential vitamin that is widely used as a nutrient or medicine in the pharmaceuticals, cosmetics, food, beverage and feed additive industries, and accounts for. (bioportfolio.com)
  • Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. (bioportfolio.com)
  • Iron-deficiency anaemia is one of the most prevalent and poten-tially serious forms of nutrient deficiency anaemias in the world [1,2]. (indmedica.com)
  • Ascorbic acid (Vitamin C) is an important nutrient in fish diets and especially in freshwater fish. (ukessays.com)
  • When this nutrient is supplied in the fish meal the food must be protected from aerobic oxidation which turns ascorbic acid in its inactive form. (ukessays.com)
  • One common type of ascorbic acid, L-ascorbic acid, is also known as the essential human nutrient, vitamin C. (3fatchicks.com)
  • A person with an addiction problem while also having a deficiency in vitamin C can significantly improve their recovery time by tackling their nutrient deficiency. (naturalnews.com)
  • Eating oranges, which are a good source of vitamin C, will help prevent a deficiency of the nutrient. (wisegeek.com)
  • Symptoms of mild deficiency may include faulty bone and tooth development, gingivitis , bleeding gums, and loosened teeth. (rxlist.com)
  • Signs of deficiency are bleeding gums, tendency to bruise, swollen or painful joints, nosebleeds, anemia, lowered resistance to infections, and slow healing of wounds and fractures. (thefreedictionary.com)
  • noun A disease caused by deficiency of vitamin C, characterized by spongy and bleeding gums, bleeding under the skin, and extreme weakness. (wordnik.com)
  • There have been differing reports on the role of dietary ascorbic acid in iron absorption, especially non-heme iron. (biomedres.info)
  • We are of the opinion that ascorbic acid plays important role in intestinal absorption of iron, especially in low levels of serum iron. (biomedres.info)
  • Its parenteral administration is desirable for patients with an acute deficiency or for those whose absorption of orally ingested ascorbic acid (vitamin c) is uncertain. (rxlist.com)
  • Ascorbic acid and iron polysaccharide may decrease the absorption of other medicines. (everydayhealth.com)
  • Ascorbic acid and iron polysaccharide may decrease the absorption of the drugs listed above. (everydayhealth.com)
  • A large excess of ascorbic acid may cause a burning sensation during urination, diarrhea, skin rash, and nausea and may disturb the absorption and metabolism of cyanocobalamin. (thefreedictionary.com)
  • Abscorbic acid commonly known as Vitamin C is a water-soluble vitamin, which is necessary in the body to form collagen in bones, cartilage, muscle, and blood vessels and aids in the absorption of iron. (news-medical.net)
  • Ascorbic acid (vitamin C is necessary for the formation of collagen, reducing free radicals, and aiding in iron absorption. (worldwidescience.org)
  • It also partially degrades phytic acid, which is a potent inhibitor of mineral absorption, an inhibitor of the digestive enzyme trypsin and an enemy of dental health ( 1 ). (blogspot.com)
  • The combination of grinding and sour fermentation causes grains to efficiently degrade their own phytic acid (as long as they haven't been heat treated first), making minerals much more available for absorption ( 4 , 5 , 6 , 7 ). (blogspot.com)
  • Iron deficiency results in anemia which may increase the risk of death from hemorrhage during delivery, but its effects on fetal development and birth outcomes is still unclear. (slideshare.net)
  • A nutritional condition produced by a deficiency of VITAMIN K in the diet, characterized by an increased tendency to hemorrhage (HEMORRHAGIC DISORDERS). (mcw.edu)
  • It seems logical to suppose then that a reduction in the vitamin C in the body would result in weakness or increased permeability of the capillaries before the more definite signs of vitamin C deficiency, as hemorrhage, result. (whale.to)
  • Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. (nih.gov)
  • The active form is ascorbic acid and the inactive dehydroascorbic acid is white crystalline compounds. (ukessays.com)
  • Also this vitamin is very instable to oxidation in presence of elements like cooper or iron because increase oxidation and inactive ascorbic acid into dehydroascorbic acid. (ukessays.com)
  • Vitamin C exists in two forms, the reduced form (ascorbic acid) and the oxidized form (dehydroascorbic acid) (Figure 1). (ukessays.com)
  • Dietary ascorbate intake affects steady state tissue concentrations in vitamin C-deficient mice: tissue deficiency after suboptimal intake and superior bioavailability from a food source (kiwifruit). (harvard.edu)
  • We studied the influence of ascorbate (vitamin C) on peripheral blood mononuclear cells (PBMC) of pigs with hereditary deficiency in ascorbate synthesis. (nih.gov)
  • Throughout evolution, a number of animals including humans have lost the ability to synthesize ascorbic acid (ascorbate, vitamin C), an essential molecule in the physiology of animals and plants. (frontiersin.org)
  • L-Ascorbic Acid (L-threo-hex-2-enono-1,4-lactone, ascorbate), also called vitamin C, is an essential antioxidant molecule in plant and animal metabolism and also functioning as a cofactor in many enzymes. (frontiersin.org)
  • Vitamin C supplements are available in two forms: ascorbic acid and ascorbate. (memorialhospitaljax.com)
  • The effect of subclinical ascorbate deficiency on periodontal health in nonhuman primates. (thejcdp.com)
  • It is a condition characterized by general weakness, anemia, gum disease, and skin hemorrhages caused by a prolonged deficiency of vitamin C or ascorbic acid in the diet. (medindia.net)
  • Anemia is the second most common affliction in the world and iron deficiency is the most common cause of it (1) . (whale.to)
  • The incidence of iron deficiency anemia is much greater in India than western countries, despite the fact that daily iron intake of Indians is twice that of westerners (2 , 3) . (whale.to)
  • This is distinct from anemia caused by deficiency of folic acid or vitamin B 12 . (wikipedia.org)
  • 1. Deficiency caused by: - malabsorption (eg, sprue, enteritis, Diphyllobothrium latum) - lack of intrinsic factor (pernicious anemia, gastric bypass surgery) - absence of terminal ileum (surgical resection, eg, for Crohn disease) - or insufficient intake (eg, veganism). (brainscape.com)
  • The iron deficiency has been pointed out as the most frequent cause of anemia in the world, both in countries with low level of development and in the highly industrialized ones. (sld.cu)
  • In Cuba, the iron-deficiency anemia constitutes a problem of health that affects fundamentally older infants, adolescents, women in fertile age and pregnant women. (sld.cu)
  • Iron polysaccharide is used as a dietary supplement, and to prevent and to treat iron deficiencies and iron deficiency anemia. (everydayhealth.com)
  • It is used as an antiscorbutic and nutritional supplement, in the treatment of iron-deficiency anemia and chronic iron toxicity, and in the labeling of red blood cells with sodium chromate Cr 51 . (thefreedictionary.com)
  • The deficiency leads to symptoms of weakness, anemia, gum disease , and skin problems. (medicalnewstoday.com)
  • In humans, an exogenous source of ascorbic acid is required for collagen formulation and tissue repair. (nih.gov)
  • a vitamin C deficiency results in impaired collagen synthesis. (medscape.com)
  • The typical pathologic manifestations of vitamin C deficiency, including poor wound healing, are noted in collagen-containing tissues and in organs and tissues such as skin, cartilage, dentine, osteoid, and capillary blood vessels. (medscape.com)
  • The most important signs of the deficiency of vitamin C are anorexia, reduction of growth, reduced bone collagen, lordosis, scoliosis, haemorrhagies in the fins and in the internal organs, problems in the gill filaments, erosion of the fins, and increased mortality. (ukessays.com)
  • Effects of L-ascorbic acid on lysyl oxidase in the formation of collagen cross-links. (thejcdp.com)
  • A distinctive feature of collagen is the regular arrangement of amino acids in each of the three chains of the collagen subunits. (newworldencyclopedia.org)
  • [2] Countries do not always agree on the amounts of vitamins needed to safeguard against deficiency. (wikipedia.org)
  • Ascorbic acid supplements are available alone and in combination with other vitamins. (medlineplus.gov)
  • The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration. (nih.gov)
  • This is supported by the fact that despite the national policy that pregnant women in all trimesters should be prescribed ferrous sulphate (200mg) with folic acid (5mg) daily from the day of first visit to the antenatal clinic to the day of delivery [8], there is still increasing cases of anaemia in pregnancy. (indmedica.com)
  • Folic acid deficiency can lead to hematological consequences, pregnancy complications and congenital malformations, but again the association with other birth outcomes is equivocal. (slideshare.net)
  • Ascorbic acid is prone to oxidation in vivo, and body stores are affected by environmental and lifestyle factors (eg, smoking), biological conditions (eg, inflammation, iron excess), and pathologic conditions (eg, malabsorption) that may alter its oxidation. (medscape.com)
  • Excess amounts of ascorbic acid are excreted unchanged or as metabolites. (medscape.com)
  • Thiamine (Vitamine B 1 ) deficiency is especially common in countries that do not require fortification of wheat and maize flour and rice to replace the naturally occurring thiamine content lost to milling , bleaching and other processing. (wikipedia.org)
  • Ascorbic Acid injection is a clear, colorless to slightly yellow sterile solution of Ascorbic Acid in Water for Injection, for intravenous, intramuscular or subcutaneous use. (nih.gov)
  • Recent studies suggest that intravenous ascorbic acid (IVAA) may circumvent rHuEpo resistance. (drcalapai.net)
  • Sodium Hydroxide and/or Hydrochloric Acid may have been used to adjust pH. (rxlist.com)
  • Ascorbic Acid 500 mg, Disodium Edetate 0.25 mg, Sodium Hydroxide 110 mg, in Water for Injection q.s. pH (range 5.5 to 7.0) adjusted with Sodium Bicarbonate and Sodium Hydroxide. (nih.gov)
  • Each mL contains: Ascorbic Acid 500 mg, Edetate Disodium 0.25 mg, Water for Injection q.s. pH (range 5.5-7.0) adjusted with Sodium Bicarbonate and Sodium Hydroxide. (nih.gov)
  • In the body it is found as ascorbic acid or sodium or calcium ascorbates. (gurze.com)
  • Some forms of ascorbic acid contain sodium and should be avoided if you are on a sodium- or salt-restricted diet. (medlineplus.gov)
  • Ascorbic Acid Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Electrocatalytic oxidation of ascorbic acid (AA) at a carbon paste electrode, chemically modified 2,2'-[3,6-dioxa-1,8-octanediylbis(nitriloethylidyne)]-bis-hydroquinone, was thoroughly investigated. (biomedsearch.com)
  • Ascorbic acid is metabolized in the liver by oxidation and sulfation. (medscape.com)
  • Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta oxidation. (wikipedia.org)
  • Gamma-butyrobetaine dioxygenase also catalyses the oxidation of mildronate to form multiple products including malonic acid semialdehyde, dimethylamine, formaldehyde and (1-methylimidazolidin-4-yl)acetic acid, which is proposed to be formed via a Stevens rearrangement mechanism. (wikipedia.org)
  • Ascorbic acid ( vitamin C ) is a water-soluble vitamin. (rxlist.com)
  • Vitamin C, or ascorbic acid, is a water-soluble vitamin that is present in large quantities in the body. (gurze.com)
  • L-Ascorbic Acid (Vitamin C) is a water-soluble vitamin that is essential for growth and repair of tissue. (cerilliant.com)
  • The primary purpose of this study is to evaluate the safety and tolerability of vitamin C (ascorbic acid) given by injection into the vein. (bioportfolio.com)
  • Ascorbic Acid (vitamin c) Injection is a sterile solution. (rxlist.com)
  • Each mL contains: Ascorbic Acid (vitamin c) 250 mg and Edetate Disodium 0.025% in Water for Injection qs. (rxlist.com)
  • Ascorbic Acid (vitamin c) Injection, USP, 250 mg/mL is available in 2 mL ampules, in cartons of 25. (rxlist.com)
  • Animal reproduction studies have not been conducted with Ascorbic Acid Injection. (nih.gov)
  • It is also not known whether Ascorbic Acid Injection can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. (nih.gov)
  • Ascorbic Acid Injection should be given to a pregnant woman only if clearly needed. (nih.gov)
  • Caution should be exercised when Ascorbic Acid Injection is administered to a nursing woman. (nih.gov)
  • Ascorbic acid is administered by injection in severe deficiency states and where persistent vomiting, diarrhoea or other conditions prevent adequate utilisation by mouth. (intekom.com)
  • Higher infectivity and mortality rates and a more severe type of disease were encountered in guinea-pigs fed a purified diet deficient in ascorbic acid than in those on the same diet with an adequate supplement of this vitamin. (ajtmh.org)
  • Plasma ascorbic acid was low (less than 23 mu mol/L) in 11 (85%) of the 13 untreated PCT patients and deficient (less than 11 mu mol/L) in 8 (62%), Two patients with normal ascorbic acid levels (45 and 62 mu mmol/L) had consumed multivitamins. (hepcprimer.com)
  • In experimental animal models, ascorbic acid modulates chemically induced uroporphyrin accumulation, The purpose of this study was to determine whether ascorbic acid is decreased in the plasma of patients with PCT. (hepcprimer.com)
  • Vitamin C is known chemically as ascorbic acid, and this compound is very important for a range of bodily functions. (wisegeek.com)
  • Most animals can synthesize their own ascorbic acid within their bodies, but humans don't have this capability. (3fatchicks.com)
  • In other experiments, however, ascorbic acid has been shown to prevent the formation of nitrosamines compounds found to produce tumors in laboratory animals and possibly also in humans. (catalogs.com)
  • Pauling argued that because humans lack a functional form of L-gulonolactone oxidase, an enzyme required to make vitamin C that is functional in most other mammals, plants, insects, and other life forms, humans have developed a number of adaptations to cope with the relative deficiency. (wikipedia.org)
  • Chemical determinations of ascorbic acid levels in the plasma, muscle, liver and spleen revealed no significant alterations in the distribution of tissue ascorbic acid in infected guinea-pigs. (ajtmh.org)
  • Cham B.E., Roeser H.P. and Nikles A.C. (1990) Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea pigs. (edu.au)
  • Long-term low ascorbic acid intake reduces bone mass in guinea pigs. (thejcdp.com)
  • The following estimations were performed on both the samples immediately after the collection - blood hemoglobin (Hb) (cyanmethemoglobin method), serum iron (8) , total iron binding capacity (TIBC) (8) , percent saturation (PS), (by calculation), serum ferritin (9) , serum copper (10) , total proteins (11) and ascorbic acid (12) . (whale.to)
  • Protein Soy, fish, chicken, turkey, eggs, pork, extract, and cheese are examples of proteins that seat adequate principal amino acids to quicken protein fusion and that being the case game reserve muscle mass. (bonetumor.org)
  • Bacterial fermentation produces lysine, often increasing its concentration by many fold and making grains nearly a "complete protein", i.e. one that contains the ideal balance of essential amino acids as do animal proteins ( 11 , scroll down to see graph). (blogspot.com)
  • In 1928, when Albert Szent-Gyorgyi isolated the active ingredient, he called it the anti-scorbutic principle, or ascorbic acid. (memorialhospitaljax.com)
  • A child presenting a "scorbutic tongue" due to vitamin C deficiency. (wikipedia.org)
  • In the United States, hemolysis induced by infection or drugs is the most common clinical manifestation of G-6-PD deficiency (2). (annals.org)
  • There is a strong correlation between gingival inflammation and clinical and sub-clinical ascorbic acid deficiency . (bvsalud.org)
  • This certified solution standard is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in HPLC /UV or electrochemical (EC) L-ascorbic acid clinical or dietary supplement testing applications. (cerilliant.com)
  • Clinical testing of L-ascorbic acid levels is performed to evaluate vitamin C deficiency. (cerilliant.com)
  • Therefore, working to reduce the postoperative mortality due to respiratory involvement, we have given ascorbic acid to those patients who, postoperatively, showed clinical signs of moisture in the lungs with sometimes patches of consolidation, accompanied by a rise in temperature and respiratory rate. (whale.to)
  • [ 7 ] The enzyme L-gluconolactone oxidase, which would usually catalyze the conversion of L-gluconogammalactone to L-ascorbic acid, is defective due to a mutation or inborn error in carbohydrate metabolism. (medscape.com)
  • Consumption of fruits and vegetables or diets fortified with vitamin C is essential to avoid ascorbic acid deficiency. (medscape.com)
  • Those who eat plenty of fruits and vegetables shouldn't worry about vitamin C deficiency. (3fatchicks.com)
  • Dietary ascorbic acid, or vitamin C, is plentiful in a number of fruits and vegetables. (3fatchicks.com)
  • Ascorbic acid (vitamin C) occurs naturally in foods such as citrus fruit, tomatoes, potatoes, and leafy vegetables. (wellspan.org)
  • The dietary survey of vegetarian mothers revealed that their diet was lacking in ascorbic acid as the consumption of fruits and citrus fruits was meagre (5) . (whale.to)
  • Consuming citrus fruits, like lemons, will prevent vitamin C deficiency. (wisegeek.com)
  • The ICD-10 code range for ICD-10 Other nutritional deficiencies E50-E64 is medical classification list by the World Health Organization (WHO). (aapc.com)
  • See 21 Hidden Clues to Diagnosing Nutritional Deficiencies , a Critical Images slideshow, to help identify clues to conditions associated with malnutrition. (medscape.com)
  • Nutritional deficiencies are rarely reported in developed countries. (worldwidescience.org)
  • Ascorbic acid is used to treat and prevent vitamin C deficiency. (everydayhealth.com)
  • It is used to treat or prevent vitamin C deficiency. (drugs.com)
  • Older adults are at the highest risk for vitamin C deficiency, since they're most likely to suffer from poor nutrition. (3fatchicks.com)
  • The elderly often suffer from Vitamin C deficiency, so should make sure they eat a balanced diet. (wisegeek.com)
  • Plasma total ascorbic acid concentrations were measured using a colorimetric method involving a reaction between ascorbic acid, 2,6 dichlorophenol-indophenol, thiourea and dinitrophenyl hydrazine. (wiley.com)
  • Talk to your doctor and pharmacist before taking ascorbic acid and iron polysaccharide if you take any other prescription or over-the-counter medicines. (everydayhealth.com)
  • tell your doctor and pharmacist if you are allergic to ascorbic acid, any other medications, or any of the ingredients in ascorbic acid products. (medlineplus.gov)
  • Ascorbic acid in the prevention and treatment of cancer. (thejcdp.com)
  • Infants-Feeding babies evaporated or boiled milk can cause vitamin C deficiency. (epnet.com)
  • Effects of serotonin, carbamylcholine, and ascorbic acid on leukocyte cyclic GMP and chemotaxis. (thejcdp.com)
  • Exogenous supplementation with ascorbic acid (an antioxidant) rescues the growth deficiency of the fur mutant in rice leaves. (apsnet.org)
  • No exogenous ascorbic acid should be ingested for 48 to 72 hours before amine dependent stool occult blood tests are conducted because possible false negative results may occur. (nih.gov)
  • Iodine deficiency during pregnancy results in cretinism and possible fetal wastage and preterm delivery. (slideshare.net)
  • Deficiency of other minerals such as magnesium, selenium, copper, and calcium has also been associated with complications of pregnancy, childbirth or fetal development. (slideshare.net)
  • Animal studies have shown that vitamin C deficiency in a woman during pregnancy can lead to problems with fetal brain development. (medicalnewstoday.com)
  • The explanations for this difference probably lie in the timing of the vitamin C dose in relation to the serum iron measurement and the fact that the majority of the subjects in the present study did not have iron overload or ascorbic acid deficiency of the severity described by Wapnick et al. (freethesaurus.com)
  • Blood sample collected from each subject was analyzed for hematological (haemoglobin-Hb, packed cell volume-PCV and mean cell haemoglobin concentration-MCHC) and biochemical (serum iron and ascorbic acid) parameters. (biomedres.info)
  • 0.05) between the serum iron and ascorbic acid in the first and second trimesters and the control group. (biomedres.info)
  • Hemodialysis (HD) patients with functional iron deficiency (FID) often develop resistance to recombinant human erythropoietin (rHuEpo). (drcalapai.net)
  • The most important factors known to be associated with this condition are socio-economic status, poor diet, poor sanitation and various infections and infestations .Anaemia in pregnancy is defined as a haemoglobin level of less than 11.0g/dl and iron-deficiency contributes significantly to this, especially among women of south eastern Nigeria [3]. (indmedica.com)
  • Iron-deficiency anaemia is one of the direct and indirect causes of maternal mortality and can only be arrested by early detection and management during antenatal visits. (indmedica.com)
  • Complications of iron-deficiency anaemia in pregnancy include, among others, impaired oxygen transport (leading to hypoxia) and abnormal basic cell functions. (indmedica.com)
  • Ascorbic acid and iron polysaccharide may also be used for purposes not listed in this medication guide. (everydayhealth.com)
  • Do not take more ascorbic acid and iron polysaccharide than is prescribed for you or than is directed on the package. (everydayhealth.com)
  • If you do not have an iron deficiency, talk to your doctor about the use of ascorbic acid and iron polysaccharide. (everydayhealth.com)
  • Generally, ascorbic acid and iron polysaccharide should not be taken chronically by individuals with a normal iron balance. (everydayhealth.com)
  • FDA pregnancy category C. It is not known whether ascorbic acid and iron polysaccharide will harm an unborn baby. (everydayhealth.com)
  • It is not known whether ascorbic acid and iron polysaccharide passes into breast milk or if it could harm a nursing baby. (everydayhealth.com)
  • This list is not complete and other drugs may interact with ascorbic acid and iron polysaccharide. (everydayhealth.com)
  • Results of tests for glycosuria, uric acid, and iron may be inaccurate when the patient is receiving large amounts of the vitamin. (thefreedictionary.com)
  • One of the commonest food myths is that vegetarians and vegans have a higher risk of iron deficiency anaemia because they don't eat meat. (scribd.com)
  • Zinc deficiency has been associated in some, but not all studies with complications of pregnancy and delivery, as well as with growth retardation,congenital abnormalities and retarded neurobehavioral and immunological development in the fetus. (slideshare.net)
  • Solutions of ascorbic acid deteriorate rapidly, and it is not stored in the body to any extent. (thefreedictionary.com)
  • Under the right conditions, which are easy to achieve, lactic acid bacteria rapidly acidify the batter. (blogspot.com)
  • Continuous blue lighting and elevated carbon dioxide concentration rapidly increase chlorogenic acid content in young lettuce plants. (researchmap.jp)
  • Reduced-serum vitamin C and increased uric acid levels in normal-tension glaucoma. (harvard.edu)
  • Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with established gout. (news-medical.net)
  • Vitamin C supplementation, alone or in combination with allopurinol, appears to have a weak effect on lowering uric acid levels in gout patients according to the results published in the American College of Rheumatology (ACR) journal, Arthritis & Rheumatism. (news-medical.net)
  • Their summary as to the r le of ascorbic acid in the body is that its action is to maintain supporting tissue of mesenchymal origin, and deficiency results in failure of formation and maintenance of intercellular materials. (whale.to)
  • According to new studies up to three quarters of elderly in India have vitamin C deficiency due to poor dietary habits, smoking and consumption of tobacco. (medindia.net)
  • Note the perifollicular purpura and the corkscrew hairs characteristic of severe vitamin C deficiency in this patient on chronic total parenteral nutrition. (renalandurologynews.com)
  • Severe vitamin C deficiency is usually defined as a deficiency that has gone on for months or even years at a time. (wisegeek.com)
  • Niacin deficiency is a consequence of a diet low in both niacin and the amino acid tryptophan , a precursor for the vitamin. (wikipedia.org)
  • Taking vitamin C by mouth or as a shot improves a genetic disorder in newborns in which blood levels of the amino acid tyrosine are too high. (rxlist.com)
  • The main limiting amino acid in grains is lysine. (blogspot.com)

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