A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)
An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. Scurvy is characterized by bleeding in any tissue, weakness, ANEMIA, spongy gums, and a brawny induration of the muscles of the calves and legs.
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Rats bearing mutant genes which are phenotypically expressed in the animals.
Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.
Plasma glycoproteins that form a stable complex with hemoglobin to aid the recycling of heme iron. They are encoded in man by a gene on the short arm of chromosome 16.
A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).
Detection of RNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane followed by hybridization with labeled NUCLEIC ACID PROBES.
A surgical specialty concerned with the study, diagnosis, and treatment of diseases of the urinary tract in both sexes, and the genital tract in the male. Common urological problems include urinary obstruction, URINARY INCONTINENCE, infections, and UROGENITAL NEOPLASMS.
An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)
An enzyme involved in the metabolism of ASCORBIC ACID and aldarate. It catalyzes the oxidation of L-gulono-1,4-lactone to L-xylo-hex-3-ulonolactone.
A subspecialty of internal medicine concerned with the anatomy, physiology, and pathology of the kidney.
A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
Process of substituting a symbol or code for a term such as a diagnosis or procedure. (from Slee's Health Care Terms, 3d ed.)
An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form.
A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.
Porphyrins with four acetic acid and four propionic acid side chains attached to the pyrrole rings.
Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules.
A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
Time period from 1501 through 1600 of the common era.
Time period from 1601 through 1700 of the common era.
Areas set apart as burial grounds.
The practice of medicine concerned with conditions affecting the health of individuals associated with the marine environment.
The quality of not being miscible with another given substance without a chemical change. One drug is not of suitable composition to be combined or mixed with another agent or substance. The incompatibility usually results in an undesirable reaction, including chemical alteration or destruction. (Dorland, 27th ed; Stedman, 25th ed)
A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)
A group of 3-hydroxy-4-keto-FLAVONOIDS.
A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.
Differential and non-random reproduction of different genotypes, operating to alter the gene frequencies within a population.
The state that distinguishes organisms from inorganic matter, manifested by growth, metabolism, reproduction, and adaptation. It includes the course of existence, the sum of experiences, the mode of existing, or the fact of being. Over the centuries inquiries into the nature of life have crossed the boundaries from philosophy to biology, forensic medicine, anthropology, etc., in creative as well as scientific literature. (Random House Unabridged Dictionary, 2d ed; Dr. James H. Cassedy, NLM History of Medicine Division)
Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.
A species of gram-negative, facultatively anaerobic bacteria. This organism shows remarkable pathobiologic properties: it adheres to cell surfaces, deeply penetrates into the cell, and strongly adsorbs human red blood cells and human CD4+ lymphocytes and monocytes. M. penetrans was first isolated from the urogenital tract of patients with AIDS and high frequencies of antibodies to it are seen in HIV-infected patients.
A species of the genus MYCOPLASMA, originally isolated infrequently from the lower genital tract of humans, and possessing uncertain pathogenicity. The incognitus strain of M. fermentans has been identified in necrotizing lesions of multiple organs from AIDS and non-AIDS patients dying of an acute influenza-like disease.
Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
Elements of limited time intervals, contributing to particular results or situations.
A plant genus of the family CUCURBITACEAE that is the source of bryodin 1 (a ribosome-inactivating protein).
A plant genus of the family CRASSULACEAE. Members contain rhodioloside. This roseroot is unrelated to the familiar rose (ROSA). Some species in this genus are called stonecrop which is also a common name for SEDUM.
The stonecrop plant family of the order ROSALES, subclass Rosidae, class Magnoliopsida that grow in warm, dry regions. The leaves are thick. The flower clusters are red, yellow, or white.

Dietary antioxidants and magnesium in type 1 brittle asthma: a case control study. (1/213)

BACKGROUND: Type 1 brittle asthma is a rare form of asthma. Atopy, psychosocial factors and diet may contribute to this condition. As increased dietary magnesium has a beneficial effect on lung function and selenium, vitamins A, C and E have antioxidant properties, a study was undertaken to test the hypothesis that patients with brittle asthma have diets deficient in these nutrients compared with subjects with non-brittle asthma and healthy adults. METHODS: A case control study of the dietary intakes of 20 subjects with brittle asthma, 20 with non-brittle asthma, and 20 healthy adults was performed using five day weighed dietary records. Intake of magnesium was the primary outcome measure with selenium and vitamins A, C and E as secondary outcomes. Serum levels were measured at the same time as the dietary assessment. RESULTS: Sixty subjects (27 men) of mean age 49.5 years were recruited and completed the study. Subjects with brittle asthma had statistically lower median dietary intakes of vitamins A and E than the other groups (vitamin A: brittle asthma 522.5 micrograms/day, non-brittle asthma 869.5 micrograms/day, healthy adults 806.5 micrograms/day; vitamin E: brittle asthma 4.3 mg/day, non-brittle asthma 4.6 mg/day, healthy adults 4.5 mg/day). Median dietary intakes for the other nutrients were not significantly different between groups. Serum levels were within normal ranges for each nutrient in all subjects. Intakes less than the reference nutrient intake (RNI) for magnesium and vitamins A and C, and less than the safe intake (SI) for vitamin E were more likely in patients with brittle asthma than in those with non-brittle asthma. CONCLUSION: Nutrient deficiency and reduced antioxidant activity may contribute to disease activity in type 1 brittle asthma, although a prospective study of replacement therapy will be needed to confirm this hypothesis.  (+info)

Parenteral vitamin requirements during intravenous feeding. (2/213)

Serum vitamin levels of 40 patients undergoing parenteral nutrition over a 5-to 42-day period were studied while the subjects received daily water-soluble and once weekly fat soluble vitamin formulations intravenously. Initial serum deficiencies of vitamins A, C, and folate were noted in a large portion of the severely malnourished population. At the replacement levels used in this study a small number of patients developed subnormal levels of vitamins A and D. Improvement in levels for vitamin C and folate were noted for most patients. Vitamin B12 deficiencies were not noted in any patient. Currently available commercial vitamin preparations can be used with safety in the parenterally nourished population and recommended guidelines for weekly infusion of both water and fat soluble vitamins are presented.  (+info)

Aortic wall damage in mice unable to synthesize ascorbic acid. (3/213)

By inactivating the gene for L-gulono-gamma-lactone oxidase, a key enzyme in ascorbic acid synthesis, we have generated mice that, like humans, depend on dietary vitamin C. Regular chow, containing about 110 mg/kg of vitamin C, is unable to support the growth of the mutant mice, which require L-ascorbic acid supplemented in their drinking water (330 mg/liter). Upon withdrawal of supplementation, plasma and tissue ascorbic acid levels decreased to 10-15% of normal within 2 weeks, and after 5 weeks the mutants became anemic, began to lose weight, and die. Plasma total antioxidative capacities were approximately 37% normal in homozygotes after feeding the unsupplemented diet for 3-5 weeks. As plasma ascorbic acid decreased, small, but significant, increases in total cholesterol and decreases in high density lipoprotein cholesterol were observed. The most striking effects of the marginal dietary vitamin C were alterations in the wall of aorta, evidenced by the disruption of elastic laminae, smooth muscle cell proliferation, and focal endothelial desquamation of the luminal surface. Thus, marginal vitamin C deficiency affects the vascular integrity of mice unable to synthesize ascorbic acid, with potentially profound effects on the pathogenesis of vascular diseases. Breeding the vitamin C-dependent mice with mice carrying defined genetic mutations will provide numerous opportunities for systematic studies of the role of antioxidants in health and disease.  (+info)

Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. (4/213)

BACKGROUND: Lack of reliable dietary data has hampered the ability to effectively distinguish between effects of smoking and diet on plasma antioxidant status. As confirmed by analyses of comprehensive food-frequency questionnaires, the total dietary intakes of fruit and vegetables and of dietary antioxidants were not significantly different between the study groups in the present study, thereby enabling isolation of the effect of smoking. OBJECTIVE: Our objective was to investigate the effect of smoking on plasma antioxidant status by measuring ascorbic acid, alpha-tocopherol, gamma-tocopherol, beta-carotene, and lycopene, and subsequently, to test the effect of a 3-mo dietary supplementation with a moderate-dose vitamin cocktail. DESIGN: In a double-blind, placebo-controlled design, the effect of a vitamin cocktail containing 272 mg vitamin C, 31 mg all-rac-alpha-tocopheryl acetate, and 400 microg folic acid on plasma antioxidants was determined in a population of smokers (n = 37) and nonsmokers (n = 38). The population was selected for a low intake of fruit and vegetables and recruited from the San Francisco Bay area. RESULTS: Only ascorbic acid was significantly depleted by smoking per se (P < 0.01). After the 3-mo supplementation period, ascorbic acid was efficiently repleted in smokers (P < 0.001). Plasma alpha-tocopherol and the ratio of alpha- to gamma-tocopherol increased significantly in both supplemented groups (P < 0.05). CONCLUSIONS: Our data suggest that previous reports of lower concentrations of plasma vitamin E and carotenoids in smokers than in nonsmokers may primarily have been caused by differences in dietary habits between study groups. Plasma ascorbic acid was depleted by smoking and repleted by moderate supplementation.  (+info)

Plasma vitamin C and food choice in the third Glasgow MONICA population survey. (5/213)

STUDY OBJECTIVE: To determine the contribution of different foods to the estimated intakes of vitamin C among those differing in plasma vitamin C levels, and thereby inform dietary strategies for correcting possible deficiency. DESIGN: Cross sectional random population survey. SETTING: North Glasgow, Scotland, 1992. PARTICIPANTS: 632 men and 635 women, aged 25 to 74 years, not taking vitamin supplements, who participated in the third MONICA study (population survey monitoring trends and determinants of cardiovascular disease). MEASUREMENTS AND MAIN RESULTS: Dietary and sociodemographic information was collected using a food frequency and lifestyle questionnaire. Plasma vitamin C was measured in non-fasted venous blood samples and subjects categorised by cut points of 11.4 and 22.7 micromol/l as being of low, marginal or optimal vitamin C status. Food sources of dietary vitamin C were identified for subjects in these categories. Plasma vitamin C concentrations were compared among groups classified according to intake of key foods. More men (26%) than women (14%) were in the low category for vitamin C status; as were a higher percentage of smokers and of those in the older age groups. Intake of vitamin C from potatoes and chips (fried potatoes) was uniform across categories; while the determinants of optimal versus low status were the intakes of citrus fruit, non-citrus fruit and fruit juice. Optimal status was achieved by a combined frequency of fruit, vegetables and/or fruit juice of three times a day or more except in older male smokers where a frequency greater than this was required even to reach a marginal plasma vitamin C level. CONCLUSION: Fruit, vegetables and/or fruit juice three or more times a day increases plasma vitamin C concentrations above the threshold for risk of deficiency.  (+info)

Vitamin C status and mortality in US adults. (6/213)

BACKGROUND: Low vitamin C status may increase the risk of mortality from cancer and cardiovascular disease. OBJECTIVE: The objective was to test whether an association existed between serum ascorbate concentrations and mortality and whether the association was modified by cigarette smoking status or sex. DESIGN: Serum ascorbate concentrations were measured in adults as part of the second National Health and Nutrition Examination Survey (1976-1980). Vital status was ascertained 12-16 y later. RESULTS: The relative risk (RR) of death, adjusted for potential confounders, was estimated by using Cox proportional hazards models. Men in the lowest (<28.4 micromol/L) compared with the highest (>/=73.8 micromol/L) serum ascorbate quartile had a 57% higher risk of dying from any cause (RR: 1.57; 95% CI: 1.21, 2.03) and a 62% higher risk of dying from cancer (RR: 1.62; 95% CI: 1.01, 2.59). In contrast, there was no increased risk among men in the middle 2 quartiles for these outcomes and no increased risk of cardiovascular disease mortality in any quartile. There was no association between serum ascorbate quartile and mortality among women. These findings were consistent when analyses were limited to nonsmokers or further to adults who never smoked, suggesting that the observed relations were not due to cigarette smoking. CONCLUSIONS: These data suggest that men with low serum ascorbate concentrations may have an increased risk of mortality, probably because of an increased risk of dying from cancer. In contrast, serum ascorbate concentrations were not related to mortality among women.  (+info)

Oral contraceptives and ascorbic acid. (7/213)

Plasma, leukocyte, and platelet ascorbic acid levels are decreased in women ingesting oral contraceptive steroids. Studies have shown that it is the estrogenic component of the oral contraceptive agents that is associated with the decresased ascorbic acid concentrations. Urinary excretion of ascorbic acid does not appear to be increased by the steroids. Although serum levels of copper are increased by estrogens and oral contraceptives, ascorbic acid catabolism does not appear to be increased (unpublished). Our preliminary data on tissue uptake of ascorbic acid suggest that changes in tissue distribution are one possible answer for the observed effects of the steroids on blood levels of ascorbic acid.  (+info)

Fractured neck of femur in black patients: a prospective study. (8/213)

We explored the role of iron overload, deficiency of vitamin C and alcohol abuse in the aetiology of cervical and intertrochanteric fractures of the neck of the femur as a result of minor trauma. We studied prospectively 72 patients (45 men, 27 women). Levels of serum iron markers, vitamin C and alcohol markers were measured. Consumption of alcohol was estimated using questionnaires. The findings were compared with those of an age- and gender-matched control group. The mean age of the men was 59.5 years and of the women 66.9 years, with a male predominance. In the men, iron overload, as shown by high levels of serum ferritin (p < 0.001) and deficiency of vitamin C (p < 0.03), as well as abuse of both Western and the traditional type of alcohol, appear to be important aetiological factors. In women, alcohol abuse was also common, but iron markers and levels of vitamin C did not differ significantly from the control group.  (+info)

Synonyms for Ascorbic acid deficiency in Free Thesaurus. Antonyms for Ascorbic acid deficiency. 23 synonyms for scurvy: contemptible, mean, bad, low, base, rotten, sorry, worthless, shabby, vile, low-down, pitiful, abject, despicable, dishonourable.... What are synonyms for Ascorbic acid deficiency?
Vitamin C is one of the most important nutrients that the human body needs. Here we tell you all you need know about Vitamin C deficiency and why you should prevent it.
Cham B.E., Roeser H.P. and Nikles A.C. (1990) Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea pigs. Biochemical Journal, 267 2: 535-537. ...
Latest urology and nephrology news, research and treatment articles for urologists and nephrologists to stay updated. Clinical reviews on renal and urology treatments.
Although vitamin C deficiency and scurvy are generally considered as pure nutritional disorders, only a minority of the vitamin C concentration is determined by food intake. In the presence of transit
A preliminary study that will be presented at the American Academy of Neurology meeting in April-May 2014 suggests that being deficient in Vitamin C raises your risk for a stroke. The lead researcher of the study, Dr. Stéphane Vannier, M.D., of Pontchaillou University Hospital in France, said that the research pointed to Vitamin C deficiency…
If PKD patients experience these symptoms, such as pale look, bleeding gums, poor appetite and fatigue, it may indicate they are suffering from vitamin C deficiency. Read on and you can find causes and solutions of these symptoms. Cause of
Like us, guinea pigs cant make vitamin C, but must obtain it from their diet. This makes them a good model for examining the effects of vitamin C deficiency.. In a recent study looking specifically at the effects of prenatal vitamin C deficiency, 80 pregnant guinea pigs were fed a diet that was either high or low in vitamin C. Subsequently, 157 of the newborn pups were randomly allocated to either a low or high vitamin C diet (after weaning), creating four conditions: high/high (controls); high/low (postnatal depletion); low/high (postnatal repletion); low/low (pre/postnatal deficiency). Only males experienced the high/low condition (postnatal depletion).. Only the postnatal depletion group showed any effect on body weight; no group showed an effect on brain weight.. Nevertheless, although the brain as a whole grew normally, those who had experienced a prenatal vitamin C deficiency showed a significantly smaller hippocampus (about 10-15% smaller). This reduction was not reversed by later ...
A recent study published in the American Journal of Epidemiology has found that one in seven young adults in Canada has a vitamin C deficiency. The study included 979 nonsmoking men and women between the ages of 20 and 29 years, who participated in the Toronto Nutrigenomics and Health Study from 2004 to 2008. The researchers used a comprehensive questionnaire in which participants were asked to assess their food intake over the previous month. From the responses, a total daily vitamin C intake was calculated for each person. Then the researchers measured the participants height, weight, waist circumference and body mass index and blood tests confirmed their vitamin C, glucose, inflammation, cholesterol and insulin levels. The results revealed that one in seven young Canadian adults has a vitamin C deficiency and that one in three has less than optimal levels of vitamin C. The findings also suggested that young adults with a vitamin C deficiency have significantly higher waist circumference, ...
Malaria is one of the most important tropical infectious diseases. Despite the fact that it is a completely preventable disease, a staggering 3.4 billion people continues to be at risk of the disease globally with 1.2 billion people at high risk particularly in high endemic and predominantly developing countries. In 2012, malaria was responsible for the death of approximately 482,000 under-five children. In Nigeria, Plasmodium falciparum malaria is responsible for around 60% of the out-patient visits to health facilities, 30% of childhood death, 25% of death in children under one year and 11% of maternal deaths. This study was carried out to determine the effect of Plasmodium falciparum parasitaemia on the serum ascorbic acid level of 60 malaria parasitized children of African descent aged 6 month-5 years visiting the children emergency unit and paediatric unit of Sokoto State Specialist Hospital in Sokoto, North Western, Nigeria. Controls included 30 non-parasitized children. Serum vitamin C ...
Vitamin C is a water-soluble vitamin and is not stored in the body in large quantities for prolonged periods of time. Since the human body cannot synthesize it, dietary intake of vitamin C on a regular basis is therefore necessary. Excess vitamin C is excreted in the urine thereby ensuring that the body has a total pool of about 1,500 milligrams (mg). Scurvy arises when a persons diet is deficient of vitamin C for about 3 months and the total body pool of vitamin C declines to levels below 350 mg.. The signs and symptoms associated with scurvy are largely due to the impaired synthesis of collagen. It is essentially the cement between cells that gives various tissues its firmness and strength. Weakening of these tissues, like the capillaries, leads to bleeding (hemorrhage), brittle bones and in children the normal growth of bone is affected. Iron absorption, immune function, the breakdown of cholesterol and formation of neurotransmitters are affected in scurvy thereby contributing to the ...
Free, official information about 2011 (and also 2012-2015) ICD-9-CM diagnosis code 267, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
It turns out that scurvy and vitamin C deficiency is still around these days. Scurvy is a disease resulting from a lack of vitamin C. Most animals can synthesize vitamin C, but not humans. We must eat foods containing vitamin C to get the vitamin. Vitamin C deficiency results in defective formation of collagen and connective tissues (in our bones, skin, tendons, muscles), and symptoms may include weakness, feeling tired, curly hair, sore arms and legs, bruising, bleeding gums, and impaired wound healing.. A recent small Australian study looked at diabetic persons with chronic foot wounds (foot ulcers that didnt heal after several months). Their vitamin C levels were tested and if found to be low, then they were given vitamin C supplements of 500 or 1000 mg daily, and the result was that within 2 to 3 weeks the wounds were healed. The one person with a zinc deficiency was given 50 mg daily of zinc supplement and that wound also promptly healed.. Treatment of scurvy is by taking vitamin C ...
Background. Vitamin C is associated with lower levels of high-sensitivity C-reactive protein (hsCRP), an inflammatory biomarker that predicts cardiovascular disease. However, whether low vitamin C intake is associated with hsCRP and cardiac event-free survival in patients with heart failure (HF) has not been examined.. Purpose. We hypothesized that patients with low vitamin C intake would have higher risk for elevated hsCRP and cardiac events than those with adequate intake of vitamin C.. Method. A total of 212 patients with HF (age 61±12 years, 34% female, 45% NYHA class III/IV) provided blood to measure serum hsCRP and were divided into 2 groups using 3mg/l of hsCRP as a cut-point. Patients completed a 4-day food diary verified with a registered dietitian. Nutrition Data System software program was used to determine intake of vitamin C. Adequacy of vitamin C intake was determined using formulas from the Institute of Medicine. Patients were followed for 1 year to determine time to first event ...
If theres one vitamin most people think they understand, it is vitamin C. This vitamin - also known as ascorbic acid - is present in many fruits and vegetables, and well known for its antioxidant properties and immune-enhancing powers. It is also responsible for aiding in the formation of connective tissue such as the skin, bones, and blood vessels. It also happens to be an essential component of health that the body is incapable of manufacturing on its own. As a result, it is critical that the human diet contain adequate sources of this nutrient.. As part of its grand mission in the body, this vitamin regenerates tissue, protects against many ailments like the cold and heart disease, helps to avoid scurvy, reduce bad cholesterol, and combat free radicals that can damage cellular integrity. It also aids in the bodys ability to absorb iron, and can delay the onset of cataracts.. Its effects on fatigue are well-documented. Though it can take several weeks of lowered vitamin C levels to produce ...
Neurological Benefits. The neurological benefits of vitamin C are profound and well-researched. This substance stimulates the production of a variety of enzymes involved in cognition. While the brain naturally produces these enzymes, it fails to produce them if you have a vitamin C deficiency.. As an antioxidant, vitamin C protects brain cells from the harmful effects of excessive stimulation. Oxidative stress leads to cell death, and vitamin C protects against oxidative stress in animal models.. Research has found that potassium channels play a role in depression. Vitamin C blocks potassium channels, which has antidepressive effects. A longitudinal study found that people who consumed adequate amounts of vitamin C were less likely to develop dementia. Since vitamin C is an antioxidant, it may also reduce the risk of Alzheimers disease.. Cardiovascular Benefits. Like other antioxidants, vitamin C appears to improve blood flow. Vitamin C deficiency increases your risk of atherosclerosis, so ...
Its wisdom thats been passed down through generations: Vitamin C, also known as ascorbic acid, can help prevent colds. Today, however. vitamin C is gaining in reputation as an amazing anti-ageing ingredient in advanced skincare formulations.. But in supplement form, its equally potent as a defender against hair loss ― and for one of the same reasons: collagen.. Collagen: Vitamin C is one of the most effective ways to boost your production of collagen, an antioxidant and protein that is equally important to a full, healthy head of hair it as it is to smooth, firm skin.. In the 1700s, it was discovered that citrus fruits could help prevent scurvy. It wasnt known why at the time, but the magic ingredient was eventually identified as vitamin C. Scurvy is actually caused by a vitamin C deficiency that disrupts the bodys ability to manufacture collagen and connective tissues in the skin.. Hair loss is a proven sign of vitamin C deficiency. Supplementing with vitamin C supports the production of ...
Vitamin C is one of the stars of skincare. Vitamin C is needed to make collagen that strengthens skin, muscles, and blood vessels and to ensure proper wound healing. Severe injury issues to increase vitamin C demands and vitamin c deficiency cause delayed healing.. Preliminary humans studies recommend that vitamin C supplementation in non-deficient people can speed healing of different varieties of wounds and trauma, including operation, minor scratches, herniated intervertebral discs, and skin ulcers. ...
When we look at the picture we are immediately drawn to the skin abnormality which is diffuse, purplish and irregular. It is in fact some mild bruising rather than a melanoma, although the latter is indeed a good thought. However, this is in part, a pseudo- red herring. It draws you away from the significant abnormality which is coiling of the hairs. Such a change is consistent with vitamin C deficiency (scurvy). One could indeed argue that the bruising is also caused by a vitamin C deficiency although there is not the typical peri-follicular hemorrhage that one sometimes sees in this condition ...
Obesity and the subsequent reprogramming of the white adipose tissue are linked to human disease-complexes including metabolic syndrome and concurrent non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). The dietary imposed dyslipidemia promotes redox imbalance by the generation of excess levels of reactive oxygen species and induces adipocyte dysfunction and reprogramming, leading to a low grade systemic inflammation and ectopic lipid deposition, e.g., in the liver, hereby promoting a vicious circle in which dietary factors initiate a metabolic change that further exacerbates the negative consequences of an adverse life-style. Large epidemiological studies and findings from controlled in vivo animal studies have provided evidence supporting an association between poor vitamin C (VitC) status and propagation of life-style associated diseases. In addition, overweight per se has been shown to result in reduced plasma VitC, and the distribution of body fat in obesity ...
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The observational study began on 01 November 2012 and is scheduled for a period of 10 years continued (until 01 November 2022). The duration of the observational study for each patient is not fixed corresponding to the character of a non-interventional study. According to the underlying disease, characterized either acute or chronic, there are 2 and 3 observations within the treatment period, respectively. Documentation comprises the course of the underlying diseases (by tracking of general and diseases-specific symptoms), drug compatibility (by ADR assessment), concomitant medication or other treatment, health economic data, details of treatment regimen and standard epidemiological data ...
Ascorbic acid is an essential nutrient involved in collagen formation, and its deficiency is associated with abnormal bone development. To examine the relation of ascorbic acid to bone mineral density and the prevalence of self-reported fractures, the authors analyzed data collected from 13,080 adults enrolled in the Third National Health and Nutrition Examination Survey (NHANES III) during 1988-1994. Because they identified three-way interactions among smoking, history of estrogen use, and dietary and serum ascorbic acid in postmenopausal women, they analyzed these relations stratified by smoking and estrogen use. Dietary ascorbic acid intake was independently associated with bone mineral density among premenopausal women (p = 0.002). Among men, serum ascorbic acid was associated in a nonlinear fashion with bone mineral density (p , 0.05), and dietary ascorbic acid intake was associated in a nonlinear fashion with self-reported fracture (p = 0.05). Among postmenopausal women without a history ...
Vitamin C deficiency causes scurvy and can compromise many bodily functions. Vitamin C is involved in mast cells and other immune cells, such as NK cells, and differ..
Metabolic syndrome (MetS) is a constellation of cardiometabolic risk factors, which together predict increased risk of more serious chronic diseases. We propose that one consequence of dietary overnutrition is increased abundance of Gram-negative bacteria in the gut that cause increased inflammation, impaired gut function, and endotoxemia that further dysregulate the already compromised antioxidant vitamin status in MetS. This discussion is timely because healthy individuals are no longer the societal norm and specialized dietary requirements are needed for the growing prevalence of MetS. Further, these lines of evidence provide the foundational basis for investigation that poor vitamin C status promotes endotoxemia, leading to metabolic dysfunction that impairs vitamin E trafficking through a mechanism involving the gut-liver axis. This report will establish a critical need for translational research aimed at validating therapeutic approaches to manage endotoxemia-an early, but ...
The premise behind the Vitamin C theory of heart disease is this: chronic scurvy. Weve all heard of sailors of long ago who brought citrus fruits along with them on their long sea voyages to avoid scurvy. Scurvy is a disease resulting from a vitamin c deficiency. The human body is unable to synthesize its own supply of vitamin c, so it needs to be supplemented through vitamin c-rich foods, and/or a vitamin supplement. Symptoms of scurvy include bleeding gums, fatigue, irritability, leg pain, easily-bruised skin, wounds that fail to heal, and more. These symptoms usually occur about 3 months after the person has been lacking enough vitamin c. Vitamin c is present in fresh fruits and vegetables, and in some meats. However, when foods are heavily processed and cooked, they lose most of this vitamin. So if your diet lacks fresh produce, you are setting yourself up for what is known as chronic scurvy. Vitamin c (aka L-ascorbic acid) is necessary for collagen production and iron absorption. It also ...
What causes your arteries to get blocked?. Atherosclerosis is a disease defined as hardening or thickening of the arteries. What allows the blood to keep flowing is the thin layer of endothelial cells.. However, there are a few factors that damage endothelial cells (and form atherosclerotic lesion) including free radicals, antioxidant deficiency, increased homocysteine levels, and vitamin C deficiency.. Plaque will accumulate when various substances are unable to migrate out of the atherosclerotic lesion. These substances include toxic metals, cellular waste, calcium, LDL cholesterol, triglycerides, and blood clotting materials.. Although the real cause of clogged arteries remains unclear, mounting evidence suggests that atherosclerosis is a complex condition which might start in childhood and develop as you get older. Factors like diabetes, insulin resistance, smoking, and hypertension are known to be damaging to the arteries.. 10 natural foods to unclog your arteries. Your doctor may prescribe ...
Scurvy is a disease now known to be caused by a vitamin C deficiency, but in Linds day, the concept of vitamins was unknown. Vitamin C is necessary for the maintenance of healthy connective tissue. In 1740 the catastrophic result of Ansons circumnavigation attracted much attention in Europe; out of 1900 men, 1400 had died, most of them allegedly from having contracted scurvy. According to Lind, scurvy caused more deaths in the British fleets than French and Spanish arms.[6] Since antiquity in various parts of the world, and since the 17th century in England, it had been known that citrus fruit had an antiscorbutic effect, when John Woodall (1570-1643), an English military surgeon of the British East India Company recommended them[7] but their use did not become widespread. Although Lind was not the first to suggest citrus fruit as a cure for scurvy, he was the first to study their effect by a systematic experiment in 1747.[8] It ranks as one of the first reported, controlled, clinical ...
Scurvy is a disease caused by vitamin C deficiency that was once common among sailors and pirates who were at sea longer than fruits and vegetables could be stored. Symptoms include malaise and lethargy, followed by spotty skin, spongy gums (ew!!), and bleeding from mucous membranes. If youre suffering from spongy gums, Brazos cant do much for you, but if your Spring Break
Description: Vitamin C must be acquired from dietary sources, as humans are unable to synthesize it. While a severe deficiency of vitamin C ultimately leads to scurvy, variations in vitamin C levels have also been associated with a wide range of chronic complex diseases, such as atherosclerosis, type 2 diabetes and cancer. A healthy diet will typically provide sufficient vitamin C, though people with problems absorbing vitamin C or people with a genetic variant may have increased risk of vitamin C deficiency.. ...
1. Lykkesfeldt J, Christen S, Wallock LM, et al. Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. Am J Clin Nutr. 2000;71:530-536. 2. Hercberg S, Preziosi P, Galan P, et al. Vitamin status of a healthy French population: Dietary intakes and biochemical markers. Int J Vitam Nutr Res. 1994;64:220-232. 3. Lowik MR, Wedel M, Kistemaker C, et al. Assessment of the adequacy of vitamin C intake in the Netherlands [abstract]. J Am Coll Nutr. 1991;10:544. 4. US Department of Agriculture. National Food Consumption Survey. 1985. 5. Baker B. Vitamin C deficiency common in hospitalized. Fam Pract News. March 1995:25. 6. Taylor CA, Hampl JS, Johnston CS. Low intakes of vegetables and fruits, especially citrus fruits, lead to inadequate vitamin C intakes among adults. Eur J Clin Nutr. 2000;54:573-578. 7. Taylor CA, Hampl JS, Johnston CS. Low intakes of vegetables and fruits, especially citrus fruits, lead ...
From zoe 9 years ago Add yours; Pick If you are diabetic you will love this recipe. Diabetes On Quizlet 2 Facts Type people with Type 1 diabetes always require insulin injections in Diabetes On Quizlet 2 Facts Type order to control blood sugar readings because they make little or no insulin. Comentarios No tiene cuenta? Diabetes Cause Frequent Urination Treatment Diabetes & Alternative Diabetes Treatment Diabetes Cause Frequent Urination Diabetic Nerve Pain Evidence grade Condition to which grade level applies; A: Vitamin C deficiency (scurvy) Scurvy is caused by a lack of vitamin C in the diet. Scribd is the worlds largest social reading and Cure For Diabetes 1 In 2016 Diabetic Sweetener :: Diabetes Type 1 Stomach Pain Article Diabetes Type 1 Stomach Pain; Diabetes is a risk diabetic friendly coconut cookies link stress between factor for pancreatic cancer but Diabetes On Quizlet 2 Facts Type its association with survival from pancreatic cancer is poorly understood. What to Do In a Mental ...
Copper and vitamin C are direct antagonists. This means that they oppose each other in the body. This is one reason many people feel better taking a lot of vitamin C. Copper tends to oxidize and destroy vitamin C in the body. Meanwhile, vitamin C chelates or removes copper from the body. This requires a dose of vitamin C of at least about 500 mg daily, far higher than the minimum daily requirement of about 60 mg. Many readers know that vitamin C is critical for connective tissues. One of the prominent symptoms of scurvy, or vitamin C deficiency, is bleeding, such as bleeding gums. This is due to connective tissue weakness. ...
One of the most common questions people ask when they first hear about the all-meat diet is, Where do you get your vitamin C? Since a vitamin C deficiency leads to scurvy, a very serious and ultimately lethal illness, it is a perfectly understandable and legitimate line of inquiry. None of the long term practitioners of…
Signs of vitamin C deficiency can appear within one month of little to no vitamin C intake. Your risk of developing periodontal disease, a severe form of...
Taking megadoses of vitamin C may lead to kidney damage, diarrhea, iron overload and accelerated atherosclerosis (hardening of the arteries). It increases the risk of kidney stones in some people. If stopped abruptly, it may result in rebound scurvy (vitamin C deficiency). Doses between 2000 and 5000 mg per day may have anti-coagulant properties, making it difficult for people to stop bleeding ...
In dermatology, there are typical examples of disorders related to dietary factors. The pathogenic, links between nutritional factor(s) and skin disease may be different.. Nutrient deficiency and nutrient excess are the simplest causes of specific diet-related cutaneous changes: scurvy (vitamin C deficiency) and acrodermantis enteropathica (zinc deficiency) are examples of the first type, and caronenoderma (carotene excess) is an example of the second type. Genetic metabolic defects or enzyme deficiencies, although subtle, may pave the way for the onset of diet-related skin disorders, where a toxic effect is exerted by the dietary factor(s): alcohol intake is responsible for porphyria curanea tarda, and the ingestion of choline- and lecithin-containing foods is the cause of eccnine bromhidrosis, with the typical fishy odor that features trimethylaminuria. More often, an immune (and complex) mechanism is involved in the pathogenesis of strictly diet-dependent skin disorders, e.g. atopic ...
s to prevent the occurrence of scurvy (sore gums and teeth) and increase body resistance to infection. Astymin C corrects vitamin C deficiency and supplements essential Amino acids during infancy. Astymin C ensures proper growth and development and strengthens body resistance in infants. Astymin C has a pleasant taste and flavor which ensures better patient compliance.. ...
Prof: So patient presents with a splinter in his finger. He has a Y chromosome, so he left it in there.... Prof: So what kind of people would you typically see Vitamin C deficiency, aka scurvy? Genius: Pirates? Prof: So why do we only take a baby aspirin instead of an adult aspirin if we…
EDIT: sorry title is supposed to say 20mg on top of red pepper. Is it too much? Sorry for typo so I think I read guinea pigs just need 30mg of C to stave off ill health from vitamin C deficiency. Today I served her 28 grams of red pepper which has 35 mg of C. The vet gave me though at our ...
Vitamin C deficiency has been assoc with frequency and duration of colds, along with immune system defects, which are of concern for children with Down Syndrome
In a society full of chemical laden, high calorie, high fat, low nutritional value convenience foods, vitamins & nutrition supplements are becoming more than just a health nut trend. Healthy, nutritional vitamins have become an absolute necessity.. A deficiency of vitamins K, E, and C, along with essential fatty acids can cause premature aging and skin cancer. Vitamin C deficiency can cause easy bleeding and bruising, hair and tooth loss, joint pain and swelling. These symptoms appear to be related to the weakening of blood vessels, connective tissue, and bone, which contain collagen.. Too little vitamin D can lead to osteoporosis, or a weakening of the skeletal system, due to compromised calcium absorption. D vitamin deficiency can also cause muscle weakness and cancer.. Blindness is one result of a diet lacking vitamin A. This type of deficiency has also been linked to immune system disorders and birth moralities.. B vitamins can cause a whole slew of health challenges when not present in ...
we are the best suppliers of Redion-XT Syrup.it is a vitamin, prescribed for anemia due to vitamin C deficiency. It helps the body make healthy new cells.
Some cells, including neutrophils, accumulate high intracellular ascorbate concentrations, which suggests that they have an important function in these cells. In this study we have used L-gulono-γ-lactone oxidase (Gulo)-/- mice, which are unable to synthesize ascorbate, to generate ascorbate-deficie …
Excess fragility of the microvasculature can lead to abnormal mucocutaneous bleeding. This is most commonly seen as a result of natural aging in the elderly but can also be seen as an aspect of Cushing Syndrome due to chronic glucocorticoid use as well as secondary to Vitamin C Deficiency and systemic amyloidosis. A discussion of these etiologies can be found on their respective pages but will not be considered further in this chapter ...
Question - Bulky uterus, endometrial thickness, delayed periods, bleeding gums. Cure for symptoms?. Ask a Doctor about diagnosis, treatment and medication for Vitamin c deficiency, Ask an OBGYN, Gynecologic Oncology
J. S. Kirkwood, Lebold, K. M., Miranda, C. L., Wright, C. L., Miller, G. W., Tanguay, R. L., Barton, C. L., Traber, M., and Stevens, J. F., Vitamin C deficiency activates the purine nucleotide cycle in zebrafish., The Journal of biological chemistry, vol. 287, no. 6, pp. 3833-41, 2012. ...
J. S. Kirkwood, Lebold, K. M., Miranda, C. L., Wright, C. L., Miller, G. W., Tanguay, R. L., Barton, C. L., Traber, M. G., and Stevens, J. F., Vitamin C Deficiency Activates the Purine Nucleotide Cycle in Zebrafish, Journal of Biological Chemistry, vol. 287, no. 6, pp. 3833 - 3841, 2012. ...
J. S. Kirkwood, Lebold, K. M., Miranda, C. L., Wright, C. L., Miller, G. W., Tanguay, R. L., Barton, C. L., Traber, M. G., and Stevens, J. F., Vitamin C Deficiency Activates the Purine Nucleotide Cycle in Zebrafish, Journal of Biological Chemistry, vol. 287, no. 6, pp. 3833 - 3841, 2012. ...
J. S. Kirkwood, Lebold, K. M., Miranda, C. L., Wright, C. L., Miller, G. W., Tanguay, R. L., Barton, C. L., Traber, M. G., and Stevens, J. F., Vitamin C Deficiency Activates the Purine Nucleotide Cycle in Zebrafish, Journal of Biological Chemistry, vol. 287, no. 6, pp. 3833 - 3841, 2012. ...
"Acute haemolysis induced by high dose ascorbic acid in glucose-6-phosphate dehydrogenase deficiency". British Medical Journal. ... Food portal Vitamin C Intravenous ascorbic acid Megavitamin therapy Orthomolecular medicine Uric acid Institute of Medicine ( ... The G6PD deficiency test is a common laboratory test. Because oxalic acid is produced during metabolism of vitamin C, ... "Vitamin C (Ascorbic Acid)". University of Maryland Medical Center. April 2002. Archived from the original on 2005-12-31. ...
... scurvy is a disease resulting from a severe deficiency of vitamin C (ascorbic acid). Vitamin C is essential for the synthesis ...
... as well as ascorbic acid deficiency. Koehler, Franz A., Special Rations for the Armed Forces: Army Operational Rations - A ... Significantly, diagnosed cases of malnourishment and vitamin deficiency, which had been reported among other light infantry ... malnourishment and vitamin deficiency) had become apparent, the Quartermaster Corps attempted to shift responsibility for ...
... ascorbic acid, vitamin D, magnesium, zinc, copper and manganese to name only a few There is a significant body of evidence ... this reason that bone growth is stunted during general malnutrition and specific bone abnormalities develop with deficiencies ...
... a song by Can Chemistry of ascorbic acid Vitamin C and the common cold Vitamin C deficiency or scurvy Vitamin C megadosage, ... Vitamin C is an essential nutrient, the compound L-ascorbic acid. Vitamin C may also refer to: Vitamin C (singer), an American ...
... high-dosages of ascorbic acid are administered intravenously to supplement these deficiencies. The use of intravenous ascorbic ... Intravenous Ascorbic Acid (also known as vitamin C or L-ascorbic acid), is a type of therapy that delivers soluble ascorbic ... In in vitro studies, the primary mechanism of high dosage intravenous ascorbic acid can be related to ascorbic acid's pro- ... intravenous ascorbic acid is contraindicated as high dosages of ascorbic acid may result in iron overloading and therefore, ...
Deficiency of vitamin C causes scurvy, formerly a major disease of sailors in long sea voyages. It is used as a food additive ... a diastereomer of ascorbic acid. Mineral ascorbates: salts of ascorbic acid Acids in wine Safety (MSDS) data for ascorbic acid ... Iodine is reduced by ascorbic acid, and, when all the ascorbic acid has reacted, the iodine is then in excess, forming a blue- ... Eighty percent of the world's supply of ascorbic acid is produced in China. Ascorbic acid is prepared in industry from glucose ...
This salvage process delays onset of deficiency.[107] Ascorbic acid also converts (reversibly) to dehydroascorbate (DHA) and ... "ascorbic acid" refer in the nutritional literature to l-ascorbate and l-ascorbic acid respectively. Ascorbic acid is a weak ... to produce ascorbic acid.[122] l-Ascorbic acid has a negative feedback on l-galactose dehydrogenase in spinach.[132] Ascorbic ... Haworth and Szent-Györgyi proposed that L-hexuronic acid be named a-scorbic acid, and chemically l-ascorbic acid, in honor of ...
Because of this, hexuronic acid was subsequently renamed ascorbic acid. 21st centuryEdit. Rates of scurvy in most of the world ... but he could not prove it without an animal-deficiency model. In 1932, the connection between hexuronic acid and scurvy was ... Ascorbic acid is also not synthesized by at least two species of caviidae, the capybara[74] and the guinea pig. There are known ... Scurvy is a disease resulting from a lack of vitamin C (ascorbic acid).[1] Early symptoms include weakness, feeling tired, and ...
Ascorbic acid, Scorbic meaning Scurvy). There is a ward named after him at St Mary's Hospital, Paddington, London. Wright was ... In 1932, the true cause of the disease was determined to be the deficiency from the diet of a particular nutrient, now called ...
This salvage process delays onset of deficiency.[97] Ascorbic acid also converts (reversibly) to dehydroascorbate (DHA) and ... "ascorbic acid" refer in the nutritional literature to L-ascorbate and L-ascorbic acid respectively. Ascorbic acid is a weak ... to produce ascorbic acid.[124] L-Ascorbic acid has a negative feedback on L-galactose dehydrogenase in spinach.[134] Ascorbic ... Vitamin C, also known as ascorbic acid and L-ascorbic acid, is a vitamin found in food and used as a dietary supplement.[2] The ...
Hill CH (1979). "Studies on the ameliorating effect of ascorbic acid on mineral toxicities in the chick". J. Nutr. 109 (1): 84- ... Some of the most common deficiency observed with chronic mercury intake is a selenium deficiency. Such deficiency might impact ... Similar to thiamine, iron aggravates mercury exposure effect while ascorbic acid will help reduce the mercury toxicity effect. ... Other deficiencies that are observed with a persisting mercury intake are vitamin E, vitamin B12 and vitamin C. Long term ...
GLO deficiency is the most common of metabolic diseases affecting children, limiting ascorbic acid biosynthesis to a minute ... This enzyme deficiency allows glutaric acid, 3-hydroxyglutaric acid and (to a lesser extent) glutaconic acid to build up to ... GA1 causes secondary carnitine deficiency, as glutaric acid, like other organic acids, is detoxified by carnitine. Mental ... This includes urine organic acid analysis, looking for glutaric acid and 3-hydroxyglutaric acid. Plasma and urine acylcarnitine ...
... ascorbic acid) spontaneously, without enzymatic action. Contents. *1 Gulonolactone oxidase deficiency. *2 Consequences of loss ... Grano A, De Tullio MC (2007). "Ascorbic acid as a sensor of oxidative stress and a regulator of gene expression: the Yin and ... However, the tissues of animal models with a GULO gene generally have high levels of ascorbic acid and so are often only ... Calabrese proposed that "the loss of an ability to synthesize ascorbic acid in humans...may have been a critical preadaptation ...
... and use ascorbic acid (vitamin C) to return the iron to its reduced state. Deprivation of ascorbate leads to deficiencies in ... It can take place on several amino acids, like lysine, asparagine, aspartate and histidine, but the most frequently ... of the protein in our bodies and contains a hydroxyproline at almost every 3rd residue in its amino acid sequence. Collagen ... hydroxylated amino acid residue in human proteins is proline. This is due to the fact that collagen makes up about 25-35% ...
The blood plasma concentration of vitamin C or ascorbic acid as a function of dose attains a plateau with a half-life of about ... The plateau principle is important in determining how much time is needed to produce a deficiency when intake is insufficient. ... This principle has been demonstrated for the response of liver enzymes that degrade amino acids to cortisone, which is a ...
Another way to treat LID is with an iron rich diet and in addition ascorbic acid or Vitamin C, contained in many types of ... "Iron Deficiency Anemia". Merck Manuals Professional Edition. Retrieved 2016-06-22. "Iron deficiency anemia - Mayo Clinic". www. ... "The fortification of common salt with ascorbic acid and iron". British Journal of Haematology. 28 (4): 483-95. doi:10.1111/j. ... "Iron absorption from rice meals cooked with fortified salt containing ferrous sulphate and ascorbic acid". The British Journal ...
Studies on metabolism of vitamin A: 7. Lowered synthesis of ascorbic acid in vitamin A deficient rats: P. Malathi and J. ... Effect of vitamin A deficiency on the concentrations of sodium and potassium in the blood plasma of rats: H. S. Juneja, S. K. ... Absorption of retinoic acid (vitamin A acid) in rats: D. S. Deshmukh, P. Malathi, K. Subba Rao and J. Ganguly, Indian J. ... Rapid conversion of retinal (vitamin A aldehyde) to retinoic acid (vitamin A acid) in the living rat: D. S. Deshmukh, P. ...
維生素C(英语:Vitamin C/ascorbic acid,又稱L-抗壞血酸,又譯維他命C)是高等靈長類動物與其他少數生物的必需營養素。是一種存在於食物中的維他命,可作為營養補充品。維生素C在大多数生物體内可藉由新陳代謝製造出來,但是有许多例外,比如 ... Effect of ascorbate deficiency on the in situ activity of gammabutyrobetaine hydroxylase. J Biol Chem 259:10764-10770, 1984. ... Total vitamin C, ascorbic
... deficiency w/o anemia 267 Ascorbic acid deficiency 268 Vitamin D deficiency 269 Other nutritional deficiencies 269.0 Deficiency ... of metabolism 277.83 Iatrogenic carnitine deficiency 277.84 Other secondary carnitine deficiency 277.85 Disorders of fatty acid ... of vitamin A deficiency 264.8 Other manifestations of vitamin A deficiency 264.9 Unspecified vitamin A deficiency 265 Thiamine ... of vitamin K 269.1 Deficiency of other vitamins 269.2 Unspecified vitamin deficiency 269.3 Mineral deficiency, not elsewhere ...
Vitamin B12 deficiency has been linked to two diabetic complications; atherosclerosis and diabetic neuropathy. Folic acid: Low ... Antioxidants: Three vitamins, ascorbic acid; α-tocopherol; and β-carotene, are well recognized for their antioxidant activities ... Mullan B. A.; Young I. S.; Fee H.; McCance D. R. (2002). "Ascorbic acid reduces blood pressure and arterial stiffness in type 2 ... Additionally, deficiency of thiamine was observed to be associated with dysfunction of β-cells and impaired glucose tolerance. ...
Johnston, C.S. (1996). "Chapter 10) The Antihistamine Action of Ascorbic Acid". Ascorbic Acid; Biochemistry and Biomedical Cell ... Some authors have suggested that certain cases of suspected shaken baby syndrome may result from vitamin C deficiency. This ... Fung EL, Nelson EA (December 2004). "Could Vitamin C deficiency have a role in shaken baby syndrome?". Pediatrics International ... concluded that there was no convincing evidence to conclude that vitamin C deficiency can be considered to be a cause of shaken ...
... thiamine and ascorbic acid and yields approximately 1,490 kilojoules (355 kilocalories) of food energy.[citation needed] Sago ... so sago cultivation is often the most ecologically appropriate form of land-use and the nutritional deficiencies of the food ...
He conducted research on scurvy that helped lead others to the discovery that ascorbic acid is a vitamin. He discovered that ... Edward Bright Vedder (June 28, 1878 - January 30, 1952) was a U.S. Army physician, a noted researcher on deficiency diseases, ... He studied beriberi, a deficiency disease affecting the peripheral nerves, and established an extract of rice bran as its ... The experiment demonstrated conclusively that beriberi was a deficiency disease rather than the result of a toxin in the ...
Ascorbic acid presence, particularly in high doses has also been shown to mediate response to psychological stress and speed ... This should make pH regulation much easier (unlike the normal potassium-deficiency situation, in which two sodium ions move in ... Brody S, Preut R, Schommer K, Schürmeyer TH (January 2002). "A randomized controlled trial of high dose ascorbic acid for ... Cortisol raises the free amino acids in the serum by inhibiting collagen formation, decreasing amino acid uptake by muscle, and ...
In addition, tyrosinase can convert tyrosine directly to l-DOPA in the presence of a reducing agent such as ascorbic acid. The ... Hyland K, Clayton PT (December 1992). "Aromatic L-amino acid decarboxylase deficiency: diagnostic methodology" (PDF). Clinical ... l-DOPA, also known as levodopa and l-3,4-dihydroxyphenylalanine, is an amino acid that is made and used as part of the normal ... l-DOPA is produced from the amino acid l-tyrosine by the enzyme tyrosine hydroxylase. l-DOPA can act as an l-tyrosine mimetic ...
The hydroxylation reaction is catalyzed by an enzyme that requires ascorbic acid (vitamin C), deficiencies in which lead to ... Amino acids are polymerised via peptide bonds to form a long backbone, with the different amino acid side chains protruding ... 20 natural amino acid notation Amino Acid 3-Letter[4]. 1-Letter[4]. ... In particular, the L-amino acids normally found in proteins can spontaneously isomerize at the C. α. {\displaystyle \mathrm {C ...
Treating two Lurgan "blue men", he discovered the use of ascorbic acid in the treatment of familial idiopathic ... He first came to prominence in the 1930s after publishing a study on the nutritional deficiencies of male factory workers in ...
Parenteral ascorbic acid as a key for regulating microcirculation in critically ill. Crit Care Med. 2008 Aug;36(8):2466-8 ... Seeliger MW, Biesalski HK, Wissinger B, Gollnick H, Gielen S, Frank J, Beck S, Zrenner E. Phenotype in retinol deficiency due ... These subjects also have night blindness and retinal dystrophy but few other signs of vitamin A deficiency." Strauss O The ... Biesalski HK, Wellner U, Weiser H. Vitamin A deficiency increases noise susceptibility in guinea pigs. J Nutr. 1990 Jul;120(7): ...
Histamine and ascorbic acid in human blood. J. Nutr. 110:662-668. Biologic Markers in Reproductive Toxicology (1989) "Cell ... The mechanism he argued to be high histamine levels associated with low serum vitamin C, the latter deficiency arising before ... Clemetson CA (1976). "Ascorbic acid and diabetes mellitus". Medical Hypotheses. 2 (5): 193-4. doi:10.1016/0306-9877(76)90037-2 ... Clemetson CA (1 April 1980). "Histamine and ascorbic acid in human blood". Journal of Nutrition. 110 (4): 662-8. doi:10.1093/jn ...
38th day acid mucopolysaccharides adrenal ascorbic acid amino sugars amount of galactosamine analysis ascorbic acid deficiency ... acid_deficiency.html?id=5N1PAAAAYAAJ&utm_source=gb-gplus-shareAscorbic acid deficiency. ... Ascorbic acid deficiency: its effect on galactosamine content, hexosamine synthesis, and UDP-N-acetyl Glucosamine-4-epimerace ... Ascorbic acid deficiency: its effect on galactosamine content, hexosamine synthesis, and UDP-N-acetyl Glucosamine-4-epimerace ...
Scurvy (Vitamin C deficiency, Ascorbic acid deficiency) Dermatology. Scurvy (Vitamin C deficiency, Ascorbic acid deficiency). * ... Vitamin C or ascorbic acid is not natively synthesized by human organisms because we lack the enzyme L-gulonolactone oxidase, ... "Regulation of collagen synthesis by ascorbic acid". Proc Natl Acad Sci USA. vol. 78. 1981. pp. 2879-82. ... A concise paper describing the role of ascorbic acid in collagen synthesis.) Noble, JM, Mandel, A, Patterson, MC. "Scurvy and ...
Ascorbic Acid-Induced Hemolysis in G-6-PD Deficiency G. DOUGLAS CAMPBELL JR., B.A.; MARTIN H. STEINBERG, M.D., F.A.C.P.; JOHN D ... Ascorbic Acid-Induced Hemolysis in G-6-PD Deficiency. Ann Intern Med. ;82:810. doi: 10.7326/0003-4819-82-6-810_1 ... Ascorbic acid (vitamin C), an essential vitamin, is commonly used in pharmacologic doses for the prevention of the common cold ... Though the origins of erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) deficiency are rooted in human antiquity, the ...
Ascorbic acid (vitamin C) deficiency (scurvy) 267. *Avitaminosis (multiple NEC) (see also Deficiency, vitamin) 269.2. *. C ( ... Ascorbic acid deficiency. *ICD-9-CM 267 is a billable medical code that can be used to indicate a diagnosis on a reimbursement ... cevitamic acid (with scurvy) 267. *. vitamin (multiple) NEC 269.2. *. A 264.9. *. with*. Bitôts spot 264.1. *. corneal 264.2. ... Nutritional Deficiencies 260-269 > Ascorbic acid deficiency 267- ... C (ascorbic acid) (with scurvy) 267. *. D (calciferol) ( ...
Chemical determinations of ascorbic acid levels in the plasma, muscle, liver and spleen revealed no significant alterations in ... rates and a more severe type of disease were encountered in guinea-pigs fed a purified diet deficient in ascorbic acid than in ... the distribution of tissue ascorbic acid in infected guinea-pigs. ... A controlled study has been made of the effect of ascorbic acid ... deficiency in guinea-pigs experimentally infected intracecally with Endamoeba histolytica trophozoites. Higher infectivity and ...
Ascorbic acid deficiency may be a cause of refractoriness to iron-therapy in the treatment of iron-deficiency anemia ... Ascorbic acid deficiency may be a cause of refractoriness to iron-therapy in the treatment of iron-deficiency anemia ... Ascorbic acid deficiency may be a cause of refractoriness to iron-therapy in the treatment of iron-deficiency anemia ...
Ascorbic acid, L-dehydroascorbic acid. Vitamin C also known as, ascorbic acid, L-ascorbic acid, dehydroascorbic acid, the ... If aspirin and standard vitamin C (ascorbic acid) are taken together in large doses, stomach irritation can occur, possibly ... Vitamin B17 - Benefits, Deficiency Symptoms And Food Sources Side Effects of a Vitamin C Overdose > Leave a Reply Cancel reply ... ClinicalTrials.gov: Ascorbic Acid. *https://www.ncbi.nlm.nih.gov/pubmed/28739448?_ga=2.153649208.128372027.1523338560- ...
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4 had normal ascorbic acid values and 4 were deficient (5 to 8 mu mol/L). Plasma ascorbic acid values were normal for all ... Ascorbic Acid Deficiency in Porphyria Cutanea Tarda. Porphyria cutanea tarda (POT), the most common form of porphyria, is ... Ascorbic acid deficiency may be one of the factors that contributes to the pathogenesis of PCT. Author: SINCLAIR PR, VET ADM ... Plasma ascorbic acid was low (less than 23 mu mol/L) in 11 (85%) of the 13 untreated PCT patients and deficient (less than 11 ...
Antonyms for Ascorbic acid deficiency. 23 synonyms for scurvy: contemptible, mean, bad, low, base, rotten, sorry, worthless, ... shabby, vile, low-down, pitiful, abject, despicable, dishonourable.... What are synonyms for Ascorbic acid deficiency? ... Synonyms for Ascorbic acid deficiency in Free Thesaurus. ... Ascorbic acid deficiency synonyms, Ascorbic acid deficiency ... Related to Ascorbic acid deficiency: Vitamin C deficiency, Vitamin E Deficiency, Folic acid deficiency ...
Ascorbic acid] since the body is unable to synthesize vitamin C. ... Ascorbic acid - Deficiency Aftermath!. Deficiency of Vitamin C ... and skin hemorrhages caused by a prolonged deficiency of vitamin C or ascorbic acid in the diet. The human body is unable to ... Scurvy is a nutritional disease caused by a diet that lacks vitamin C [Ascorbic acid]. It is a condition characterized by ... Scurvy is confirmed by a blood test for ascorbic acid showing levels , 11 mol/L and response of symptoms to treatment with ...
There have been differing reports on the role of dietary ascorbic acid in iron absorption, especially non-heme iron. We ... Role of ascorbic acid in the prevention of iron-deficiency anaemia in pregnancy. There have been differing reports on the role ... We are of the opinion that ascorbic acid plays important role in intestinal absorption of iron, especially in low levels of ... We measured some haematological and biochemical parameters to establish any correlation between serum ascorbic acid and iron ...
Intravenous ascorbic acid in hemodialysis patients with functional iron deficiency: a clinical trial * ... Recent studies suggest that intravenous ascorbic acid (IVAA) may circumvent rHuEpo resistance. The aim of our study was to show ... Hemodialysis (HD) patients with functional iron deficiency (FID) often develop resistance to recombinant human erythropoietin ( ...
... clinicaltrials.gov The study is designed to determine if high doses of intravenous ascorbic acid (vitamin C) can be effective ... Ascorbic Acid Deficiency. A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, ... High Dose Ascorbic Acid Treatment of CMT1A. This study will look at the impact of ascorbic acid (Vitamin C) on the progression ... Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation. The purpose of this study is to see if ascorbic acid ( ...
Ascorbic Acid (Vitamin C) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related ... Administration of ascorbic acid (vitamin c) completely reverses the symptoms of ascorbic acid (vitamin c) deficiency. ... Ascorbic Acid Injection, USP (vitamin c) No preservative added.. DESCRIPTION. Ascorbic acid (vitamin C) is a water-soluble ... Ascorbic Acid (vitamin c) Injection is a sterile solution. Each mL contains: Ascorbic Acid (vitamin c) 250 mg and Edetate ...
Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency. ... Ascorbic Acid (UNII: PQ6CK8PD0R) (Ascorbic Acid - UNII:PQ6CK8PD0R) Ascorbic Acid. 500 mg in 1 mL. ... The chemical name of Ascorbic Acid is L-ascorbic acid. The molecular formula is C6H806 and the molecular weight is 176.13. The ... Ascorbic Acid injection is a clear, colorless to slightly yellow sterile solution of Ascorbic Acid in Water for Injection, for ...
Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency. ... ASCORBIC ACID (UNII: PQ6CK8PD0R) (ASCORBIC ACID - UNII:PQ6CK8PD0R). ASCORBIC ACID. 500 mg in 1 mL. ... Ascorbic acid - Box 1 vial Ascorbic acid - Box 10 vials Ascorbic acid leaflet ... ASCORBIC ACID- ascorbic acid injection, solution To receive this label RSS feed. Copy the URL below and paste it into your RSS ...
... of pigs with hereditary deficiency in ascorbate synthesis. Groups of animals were depleted of, or supplemented with dietary ... Modulation of interleukin production by ascorbic acid Vet Immunol Immunopathol. 1998 Jun 30;64(1):45-57. doi: 10.1016/s0165- ... Ascorbic Acid / metabolism * Ascorbic Acid / pharmacology* * Ascorbic Acid Deficiency / drug therapy * Ascorbic Acid Deficiency ... of pigs with hereditary deficiency in ascorbate synthesis. Groups of animals were depleted of, or supplemented with dietary ...
Ascorbic Acid Deficiency. Chronic Disease. Acute Disease. Disease Attributes. Pathologic Processes. Avitaminosis. Deficiency ... Drug Information available for: Ascorbic acid Sodium ascorbate Magnesium ascorbate Genetic and Rare Diseases Information Center ... Ascorbic Acid. Micronutrients. Nutrients. Growth Substances. Physiological Effects of Drugs. Antioxidants. Molecular Mechanisms ... Vit C deficiency in acute diseases Patients with vitamin C deficiency due to a acute underlying disease treated with Pascorbin ...
Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea ... Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea ... Cham B.E., Roeser H.P. and Nikles A.C. (1990) Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not ...
Vitamin C (ascorbic acid) deficiency and excess. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ...
Deficiency of other B group vitamins. Billable Codes. E54 Ascorbic acid deficiency ... Other nutritional deficiencies ICD-10-CM Code range E50-E64. The ICD-10 code range for ICD-10 Other nutritional deficiencies ...
Key words: ascorbic acid, iron deficiency, anemia, vegetarians, hemoglobin, iron, ferritin. INTRODUCTION. Anemia is the second ... CORRECTION OF ANEMIA AND IRON DEFICIENCY IN VEGETARIANS BY ADMINISTRATION OF ASCORBIC ACID. DINESH C. SHARMA* AND RATI MATHUR. ... Ascorbic Acid (mg/dl). 00.47 00.10. 00.75 00.20. 7.03. ,0.001. 59.50. Total Proteins (g/dl). 08.33 00.47. 06.42 00.43. 0.09. NS ... Ascorbic acid: effect on ongoing iron absorption and status in iron depleted young women. Am J Clin Nutr 1990;51:649-655. ...
Ascorbic acid deficiency induced inflammation related gene expression in the livers of deficient animals. Jan 31, 2015. ... Retinoic Acid (a Vitamin A metabolite) in conjunction with IL-15 promotes rather than prevents Inflammation in CeliacsMar 09, ... Problem Substances : Trans Fatty Acids. Adverse Pharmacological Actions : Inflammatory, Tumor necrosis factorα (TNFα) up- ... Problem Substances : Hydrogenated Oil , Margarine, Trans Fatty Acids. Adverse Pharmacological Actions : Atherogenic, ...
Ascorbic acid deficiency induced inflammation related gene expression in the livers of deficient animals. Jan 31, 2015. ... Vitamin A deficiency may retard fetal lung development or influence the differentiation of critical cell lines.Nov 30, 1998. ... Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.Apr 30, 2020 ... Supplementation of vitamin D may improve wound healing and regeneration in patients with a vitamin D deficiency.May 20, 2016. ...
Deficiency of ascorbic acid in experimental diabetes. Relationship with collagen and polyol pathway abnormalities. ... Ascorbic acid metabolism and polyol pathway in diabetes.. Yue DK, McLennan S, Fisher E, Heffernan S, Capogreco C, Ross GR, ...
Vitamin C Deficiency. Intakes of less than 10 mg per day of vitamin C can result in scurvy. Symptoms of vitamin C deficiency ... Vitamin C, also called ascorbic acid, is a water-soluble vitamin. Water-soluble vitamins are stored in the body in very limited ... Populations at Risk for Vitamin C Deficiency. The following populations may be at risk for vitamin C deficiency and may require ... Ascorbic acid. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated July 7, 2016. Accessed July 21, ...
Ascorbic Acid Deficiency. A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, ... Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cows milk exclusively during ... Ascorbic Acid. A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic ... acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active ...
Ascorbic acid Vitamin B6 Vitamin B9 Vitamin B-12 Vitamin-F Dandy Walker Syndrome Undetected Nutrient Deficiencies: the Cause of ... Ascorbic acid. Vital info about vitamin C, its molecular structure, dietary sources, beneficial aspects, symptoms of deficiency ... Undetected Nutrient Deficiencies: The Cause of Ill Health. Micronutrient and antioxidant deficiencies are most common and go ... Vitamin D Deficiency. Vitamin D the sunshine vitamin is essential for strong bones. Vitamin D deficiency is reportedly ...
Ascorbic Acid Deficiency / epidemiology * Beverages * Body Mass Index * Case-Control Studies * Child, Preschool ...
  • less than 0.1mg/L indicates severe deficiency and symptoms of scurvy are typically manifest). (renalandurologynews.com)
  • Ascorbic acid deficiency results in scurvy. (nih.gov)
  • Ascorbic acid is recommended for the prevention and treatment of scurvy. (nih.gov)
  • Deficiency of ascorbic acid in the diet results in scurvy and other less serious conditions. (intekom.com)
  • The health benefits of vitamin C, also known as ascorbic acid, include the prevention and management of scurvy, common cold, and lead toxicity. (organicfacts.net)
  • Scurvy is caused by an insufficient intake or deficiency of ascorbic acid. (organicfacts.net)
  • ascorbic acid, another name for vitamin C, literally means "without scurvy. (vitanetonline.com)
  • Low levels of dietary ascorbic acid lead to the condition formerly known as scurvy. (3fatchicks.com)
  • True vitamin C deficiency is responsible for scurvy. (gurze.com)
  • Ascorbic acid is also used to prevent and treat scurvy (a disease that causes fatigue, gum swelling, joint pain, and poor wound healing from a lack of vitamin C in the body). (medlineplus.gov)
  • Scurvy is a state of dietary deficiency of vitamin C (ascorbic acid). (medscape.com)
  • Although scurvy is uncommon, it still occurs and can affect adults and children who have chronic dietary vitamin C deficiency (see the image below). (medscape.com)
  • Plasma ascorbic acid level may help in establishing the diagnosis, but this level tends to reflect the recent dietary intake rather than the actual tissue levels of vitamin C. Signs of scurvy can occur with low-normal serum levels of vitamin C. (medscape.com)
  • deficiency produces scurvy and poor wound repair. (thefreedictionary.com)
  • A deficiency of ascorbic acid causes scurvy. (thefreedictionary.com)
  • Severe deficiency results in scurvy. (thefreedictionary.com)
  • Scurvy is the classic manifestation of severe ascorbic acid deficiency. (catalogs.com)
  • Scurvy is the name for a vitamin C deficiency. (medicalnewstoday.com)
  • Symptoms of scurvy result from severe vitamin C deficiency. (medicalnewstoday.com)
  • Scurvy happens when there is a lack of vitamin C, or ascorbic acid. (medicalnewstoday.com)
  • When the voyages lasted longer than the supply of fruits and vegetables, the sailors began to suffer from vitamin C deficiency, which led to scurvy. (webmd.com)
  • Now we know that scurvy is nothing more than vitamin C deficiency. (memorialhospitaljax.com)
  • Severe deficiency of vitamin C causes scurvy. (news-medical.net)
  • Vitamin C (ascorbic acid) is a water soluble vitamin used to prevent and treat scurvy and acidify urine. (patientslikeme.com)
  • SCURVY , a disease of dietary ascorbic acid deficiency, is uncommon today. (worldwidescience.org)
  • Taking vitamin C by mouth or injecting as a shot prevents and treats vitamin C deficiency, including scurvy. (rxlist.com)
  • Vitamin C (ascorbic acid) is a water soluble vitamin found in citrus fruits and green vegetables and deficiency of which is the cause of scurvy. (wikimd.org)
  • Vitamin C deficiency is the cause of scurvy which is marked by fatigue, spongy gums, loss of teeth, ecchymosis, petechiae and excessive bleeding including bleeding from the gums, into joints and into internal organs. (wikimd.org)
  • Scurvy is a deficiency disease caused by lack of vitamin C (ascorbic acid). (coolantarctica.com)
  • Scurvy related to vitamin C deficiency ravaged and plagued previous [Anartic[ expeditions, including those to the polar regions. (wheelessonline.com)
  • Scurvy - Prolonged deficiency of ascorbic acid, also known as vitamin C, in the human body causes scurvy. (4to40.com)
  • Scurvy is a disease resulting from a lack of vitamin C (ascorbic acid). (wikipedia.org)
  • Scurvy, including subclinical scurvy, is caused by a deficiency of dietary vitamin C since humans are unable to metabolically make this chemical. (wikipedia.org)
  • Scurvy is one of the accompanying diseases of malnutrition (other such micronutrient deficiencies are beriberi or pellagra ) and thus is still widespread in areas of the world depending on external food aid. (wikipedia.org)
  • The disease scurvy, traced to vitamin C (ascorbic acid) deficiency, results when defective collagen prevents the formation of strong connective tissue. (newworldencyclopedia.org)
  • People who don't get enough are at risk for short-term problems like fatigue and certain skin problems, but longer-term deficiencies can lead to more serious conditions like anemia and scurvy . (wisegeek.com)
  • Vitamin C deficiency is known as scurvy . (healthline.com)
  • Scurvy is caused by severe and chronic deficiency of vitamin C (ascorbic acid), and is in modern times extremely rare. (theconversation.com)
  • In humans, vitamin C deficiency leads to impaired collagen synthesis, contributing to the more severe symptoms of scurvy . (wikipedia.org)
  • Scurvy is a disease resulting from a deficiency of vitamin C, since without this vitamin, collagen made by the body is too unstable to perform its function. (wikipedia.org)
  • Ascorbic acid (vitamin C), an essential vitamin, is commonly used in pharmacologic doses for the prevention of the common cold and to promote the healing of wounds. (annals.org)
  • Diabetics, patients prone to recurrent renal calculi, those undergoing stool occult blood tests and those on sodium restricted diets or anticoagulant therapy should not take excessive doses of ascorbic acid over an extended period of time. (nih.gov)
  • Vitamin C megadosage is a term describing the consumption or injection of vitamin C (ascorbic acid) in doses well beyond the current Recommended Dietary Allowance of 90 milligrams per day, and often well beyond the tolerable upper intake level of 2,000 milligrams per day. (wikipedia.org)
  • Ascorbic acid was given in 25 mg. doses, 4 times daily, until the temperature returned to normal. (whale.to)
  • Assertions that massive doses of ascorbic acid prevent colds and influenza have not been borne out by carefully controlled experiments. (catalogs.com)
  • Do not stop using ascorbic acid suddenly after long-term use at high doses, or you could have "conditional" vitamin C deficiency. (wellspan.org)
  • Kidney stones or other very bad kidney problems have rarely happened in people taking high doses of this medicine (ascorbic acid capsules and tablets) for a long time. (drugs.com)
  • While a vitamin C deficiency can lead to serious health problems, large doses of vitamin C may cause nausea and headaches. (wisegeek.com)
  • Periosteal elevation may also occur as a result of subperiosteal hemorrhage from capillary fragility as a direct result of ascorbic acid deficiency. (renalandurologynews.com)
  • Regarding the vitamin C deficiency, the investigators focus on the acquisition of data of the underlying diseases and the reduction of symptoms, that are related to oxidative stress and vitamin-C-deficiency. (clinicaltrials.gov)
  • As a result, ascorbic acid protects against oxidative stress and premature cell aging. (gurze.com)
  • Ascorbic acid combats arsenic-induced oxidative stress in mice liver. (biomedsearch.com)
  • Repeated injections of arsenic trioxide induced oxidative stress and hepatotoxicity in mice as revealed from elevated levels of glutamate oxaloacetate transaminases, glutamate pyruvate transaminases, acid and alkaline phosphatases, lipid peroxidation along with reduction of superoxide dismutase, catalase, reduced glutathione content, glutathione reductase and succinate dehydrogenase activities. (biomedsearch.com)
  • The Hp 2-2 polymers are less efficient inhibitors of hemoglobin-driven oxidative stress, leading to ascorbic acid depletion. (medscape.com)
  • Dogs hospitalised for ê72 hours had significantly greater plasma ascorbic acid concentrations on day 3 compared to days 1 and 2. (wiley.com)
  • There was no difference in plasma ascorbic acid concentrations between days 1 and 2 for dogs hospitalised for 36 to 72 hours. (wiley.com)
  • Plasma ascorbic acid concentrations were significantly greater for each day of sampling for the hospitalised dogs compared to the control dogs. (wiley.com)
  • Plasma ascorbic acid concentrations appear to increase during hospitalisation, and supplementation may not be indicated in dogs hospitalised in an intensive care unit. (wiley.com)
  • Vitamin C also known as, ascorbic acid, L-ascorbic acid, dehydroascorbic acid, the antiscorbutic vitamin, L-xyloascorbic acid and L-threo-hex-2-uronic acidy-lactone, is a much talked about vitamin, with people claiming it as a cure-all for may diseases and problems - from cancer to the common cold. (best-home-remedies.com)
  • Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. (nih.gov)
  • The active form is ascorbic acid and the inactive dehydroascorbic acid is white crystalline compounds. (ukessays.com)
  • Also this vitamin is very instable to oxidation in presence of elements like cooper or iron because increase oxidation and inactive ascorbic acid into dehydroascorbic acid. (ukessays.com)
  • Vitamin C exists in two forms, the reduced form (ascorbic acid) and the oxidized form (dehydroascorbic acid) (Figure 1). (ukessays.com)
  • Oxidized forms of the molecule such as dehydroascorbic acid are converted back to ascorbic acid by reducing agents. (wikipedia.org)
  • [3] Doing so converts vitamin C to an oxidized state - either as semidehydroascorbic acid or dehydroascorbic acid . (wikipedia.org)
  • We studied the influence of ascorbate (vitamin C) on peripheral blood mononuclear cells (PBMC) of pigs with hereditary deficiency in ascorbate synthesis. (nih.gov)
  • The serum protein or copper level did not indicate their dietary deficiency, while initial serum ascorbate level were low which rose by 60% on therapy. (whale.to)
  • Throughout evolution, a number of animals including humans have lost the ability to synthesize ascorbic acid (ascorbate, vitamin C), an essential molecule in the physiology of animals and plants. (frontiersin.org)
  • L-Ascorbic Acid (L-threo-hex-2-enono-1,4-lactone, ascorbate), also called vitamin C, is an essential antioxidant molecule in plant and animal metabolism and also functioning as a cofactor in many enzymes. (frontiersin.org)
  • Vitamin C supplements are available in two forms: ascorbic acid and ascorbate. (memorialhospitaljax.com)
  • Ascorbate and ascorbic acid are both naturally present in the body, since the forms interconvert according to pH . (wikipedia.org)
  • We here show that both redox and protein nitros(yl)ation status in blood and vital organs vary dynamically during development of ascorbate deficiency. (pubmedcentralcanada.ca)
  • Prolonged marginal ascorbate deficiency is associated with cell/tissue-specific perturbations in ascorbate and glutathione redox and NO status. (pubmedcentralcanada.ca)
  • The elevated cardiovascular risk in marginal ascorbate deficiency is likely to be associated with perturbations of NO/redox-sensitive signaling nodes unrelated to the regulation of vascular tone. (pubmedcentralcanada.ca)
  • This new model may have merit for the future study of redox-sensitive events in marginal ascorbate deficiency. (pubmedcentralcanada.ca)
  • This is the first study that investigated the time-course of changes in NO/redox status in blood and tissues during acute and marginal ascorbate deficiency in vivo . (pubmedcentralcanada.ca)
  • The system is characterized by a compensatory upregulation of NO production and protein nitros(yl)ation as a response to the redox stress caused by ascorbate deprivation, with a compromised reactivity following prolonged marginal deficiency. (pubmedcentralcanada.ca)
  • In contrast, marginal ascorbate deficiency, a condition caused by suboptimal vitamin C intake, is much more prevalent. (pubmedcentralcanada.ca)
  • This suggests that regular intake of ascorbic acid can protect against increased lead levels in the blood. (organicfacts.net)
  • Excessive intake of ascorbic acid increases the blood supply to the ocular areas of the body. (organicfacts.net)
  • What are the possible side effects of ascorbic acid? (wellspan.org)
  • What are some other side effects of Ascorbic Acid Capsules and Tablets? (drugs.com)
  • Its parenteral administration is desirable for patients with an acute deficiency or for those whose absorption of orally ingested ascorbic acid (vitamin c) is uncertain. (rxlist.com)
  • There have been differing reports on the role of dietary ascorbic acid in iron absorption, especially non-heme iron. (biomedres.info)
  • We are of the opinion that ascorbic acid plays important role in intestinal absorption of iron, especially in low levels of serum iron. (biomedres.info)
  • Ascorbic acid and iron polysaccharide may decrease the absorption of other medicines. (everydayhealth.com)
  • Ascorbic acid and iron polysaccharide may decrease the absorption of the drugs listed above. (everydayhealth.com)
  • A large excess of ascorbic acid may cause a burning sensation during urination, diarrhea, skin rash, and nausea and may disturb the absorption and metabolism of cyanocobalamin. (thefreedictionary.com)
  • Abscorbic acid commonly known as Vitamin C is a water-soluble vitamin, which is necessary in the body to form collagen in bones, cartilage, muscle, and blood vessels and aids in the absorption of iron. (news-medical.net)
  • Ascorbic acid (vitamin C is necessary for the formation of collagen, reducing free radicals, and aiding in iron absorption. (worldwidescience.org)
  • It also partially degrades phytic acid, which is a potent inhibitor of mineral absorption, an inhibitor of the digestive enzyme trypsin and an enemy of dental health ( 1 ). (blogspot.com)
  • The combination of grinding and sour fermentation causes grains to efficiently degrade their own phytic acid (as long as they haven't been heat treated first), making minerals much more available for absorption ( 4 , 5 , 6 , 7 ). (blogspot.com)
  • Take ascorbic acid exactly as directed. (medlineplus.gov)
  • How should I take ascorbic acid? (wellspan.org)
  • Who should not take Ascorbic Acid? (webmd.com)
  • What do I need to tell my doctor BEFORE I take Ascorbic Acid Capsules and Tablets? (drugs.com)
  • What are some things I need to know or do while I take Ascorbic Acid Capsules and Tablets? (drugs.com)
  • l-ascorbic acid (L-AA, vitamin C) is an essential vitamin that is widely used as a nutrient or medicine in the pharmaceuticals, cosmetics, food, beverage and feed additive industries, and accounts for. (bioportfolio.com)
  • Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. (bioportfolio.com)
  • One common type of ascorbic acid, L-ascorbic acid, is also known as the essential human nutrient, vitamin C. (3fatchicks.com)
  • Iron-deficiency anaemia is one of the most prevalent and poten-tially serious forms of nutrient deficiency anaemias in the world [1,2]. (indmedica.com)
  • Ascorbic acid (Vitamin C) is an important nutrient in fish diets and especially in freshwater fish. (ukessays.com)
  • When this nutrient is supplied in the fish meal the food must be protected from aerobic oxidation which turns ascorbic acid in its inactive form. (ukessays.com)
  • A person with an addiction problem while also having a deficiency in vitamin C can significantly improve their recovery time by tackling their nutrient deficiency. (naturalnews.com)
  • Eating oranges, which are a good source of vitamin C, will help prevent a deficiency of the nutrient. (wisegeek.com)
  • ascorbic acid (vitamin C) can be effective in managing solid tumor diseases. (bioportfolio.com)
  • ICD-10 Code range (E00-E89),Endocrine, nutritional and metabolic diseases, contains ICD-10 codes for Disorders of thyroid gland, Diabetes mellitus, Other disorders of glucose regulation and pancreatic internal secretion, Disorders of other endocrine glands, Intraoperative complications of endocrine system, Malnutrition, Other nutritional deficiencies. (aapc.com)
  • A plethora of papers have been published on this topic, but, although it is well known that a deficiency of vitamin C due to a low nutritional intake leads to a greater susceptibility to infections ( 5 ), the possibility of reducing the incidence of viral diseases in a well-nourished population through the use of dietary supplements based on vitamin C is not adequately supported in literature. (frontiersin.org)
  • Symptoms of mild deficiency may include faulty bone and tooth development, gingivitis , bleeding gums, and loosened teeth. (rxlist.com)
  • Signs of deficiency are bleeding gums, tendency to bruise, swollen or painful joints, nosebleeds, anemia, lowered resistance to infections, and slow healing of wounds and fractures. (thefreedictionary.com)
  • noun A disease caused by deficiency of vitamin C, characterized by spongy and bleeding gums, bleeding under the skin, and extreme weakness. (wordnik.com)
  • In experimental animal models, ascorbic acid modulates chemically induced uroporphyrin accumulation, The purpose of this study was to determine whether ascorbic acid is decreased in the plasma of patients with PCT. (hepcprimer.com)
  • Electrocatalytic oxidation of ascorbic acid (AA) at a carbon paste electrode, chemically modified 2,2'-[3,6-dioxa-1,8-octanediylbis(nitriloethylidyne)]-bis-hydroquinone, was thoroughly investigated. (biomedsearch.com)
  • Vitamin C is a water soluble vitamin known chemically as L-ascorbic acid (as kore' bik as' id). (wikimd.org)
  • Vitamin C is known chemically as ascorbic acid, and this compound is very important for a range of bodily functions. (wisegeek.com)
  • Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency. (nih.gov)
  • There are no contraindications to the administration of ascorbic acid. (nih.gov)
  • The present study was, therefore, undertaken to see the effect of administration of ascorbic acid on hemoglobin and iron status of strictly vegetarian people. (whale.to)
  • Ascorbic Acid injection is a clear, colorless to slightly yellow sterile solution of Ascorbic Acid in Water for Injection, for intravenous, intramuscular or subcutaneous use. (nih.gov)
  • Recent studies suggest that intravenous ascorbic acid (IVAA) may circumvent rHuEpo resistance. (drcalapai.net)
  • Sodium Hydroxide and/or Hydrochloric Acid may have been used to adjust pH. (rxlist.com)
  • Ascorbic Acid 500 mg, Disodium Edetate 0.25 mg, Sodium Hydroxide 110 mg, in Water for Injection q.s. pH (range 5.5 to 7.0) adjusted with Sodium Bicarbonate and Sodium Hydroxide. (nih.gov)
  • Each mL contains: Ascorbic Acid 500 mg, Edetate Disodium 0.25 mg, Water for Injection q.s. pH (range 5.5-7.0) adjusted with Sodium Bicarbonate and Sodium Hydroxide. (nih.gov)
  • In the body it is found as ascorbic acid or sodium or calcium ascorbates. (gurze.com)
  • Some forms of ascorbic acid contain sodium and should be avoided if you are on a sodium- or salt-restricted diet. (medlineplus.gov)
  • It is used as an antiscorbutic and nutritional supplement, in the treatment of iron-deficiency anemia and chronic iron toxicity, and in the labeling of red blood cells with sodium chromate Cr 51 . (thefreedictionary.com)
  • Effect of riboflavin,choline,pantothenic acid and vitamin A on the excretion of sodium in urine of rats. (nii.ac.jp)
  • Effect of single deficiency of vitamin A,thiamine,riboflavin or ascorbic acid on the dark adaptation. (nii.ac.jp)
  • In this study, we aim to determine whether the combination of Ascorbic Acid (Vitamin C), Thiamine (Vitamin B1), and Corticosteroids improves the trajectory of organ failure and reduces mortality in patients with sepsis and septic shock as compared to placebo. (clinicaltrials.gov)
  • PMID 27940189) demonstrated a remarkable benefit when the combination of Ascorbic Acid (Vitamin C), Corticosteroids, and Thiamine (Vitamin B1) were given to patients with sepsis. (clinicaltrials.gov)
  • Corticosteroids, a mainstay of therapy for refractory shock in sepsis, have also been shown to enhance the beneficial cellular effects of vitamin C. Finally, thiamine has been shown to be an effective mitochondrial resuscitator in sepsis, especially for the ~30% of septic shock patients who present with thiamine deficiency (Donnino et. (clinicaltrials.gov)
  • Ascorbic acid supplements are available alone and in combination with other vitamins. (medlineplus.gov)
  • Studies have shown that as many as 39% of those taking vitamins on a regular basis in a nursing home setting were not absorbing the same vitamins they are taking by mouth leading to significant deficiencies. (wikimd.org)
  • In humans, an exogenous source of ascorbic acid is required for collagen formulation and tissue repair. (nih.gov)
  • Pauling argued that because humans lack a functional form of L-gulonolactone oxidase, an enzyme required to make vitamin C that is functional in most other mammals, plants, insects, and other life forms, humans have developed a number of adaptations to cope with the relative deficiency. (wikipedia.org)
  • Most animals can synthesize their own ascorbic acid within their bodies, but humans don't have this capability. (3fatchicks.com)
  • In other experiments, however, ascorbic acid has been shown to prevent the formation of nitrosamines compounds found to produce tumors in laboratory animals and possibly also in humans. (catalogs.com)
  • Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta oxidation. (wikipedia.org)
  • Gamma-butyrobetaine dioxygenase also catalyses the oxidation of mildronate to form multiple products including malonic acid semialdehyde, dimethylamine, formaldehyde and (1-methylimidazolidin-4-yl)acetic acid, which is proposed to be formed via a Stevens rearrangement mechanism. (wikipedia.org)
  • Ascorbic acid is prone to oxidation in vivo, and body stores are affected by environmental and lifestyle factors (eg, smoking), biological conditions (eg, inflammation, iron excess), and pathologic conditions (eg, malabsorption) that may alter its oxidation. (medscape.com)
  • Ascorbic acid is metabolized in the liver by oxidation and sulfation. (medscape.com)
  • It is a condition characterized by general weakness, anemia, gum disease, and skin hemorrhages caused by a prolonged deficiency of vitamin C or ascorbic acid in the diet. (medindia.net)
  • Anemia is the second most common affliction in the world and iron deficiency is the most common cause of it (1) . (whale.to)
  • The incidence of iron deficiency anemia is much greater in India than western countries, despite the fact that daily iron intake of Indians is twice that of westerners (2 , 3) . (whale.to)
  • Iron deficiency results in anemia which may increase the risk of death from hemorrhage during delivery, but its effects on fetal development and birth outcomes is still unclear. (slideshare.net)
  • The iron deficiency has been pointed out as the most frequent cause of anemia in the world, both in countries with low level of development and in the highly industrialized ones. (sld.cu)
  • In Cuba, the iron-deficiency anemia constitutes a problem of health that affects fundamentally older infants, adolescents, women in fertile age and pregnant women. (sld.cu)
  • Iron polysaccharide is used as a dietary supplement, and to prevent and to treat iron deficiencies and iron deficiency anemia. (everydayhealth.com)
  • The deficiency leads to symptoms of weakness, anemia, gum disease , and skin problems. (medicalnewstoday.com)
  • a vitamin C deficiency results in impaired collagen synthesis. (medscape.com)
  • The typical pathologic manifestations of vitamin C deficiency, including poor wound healing, are noted in collagen-containing tissues and in organs and tissues such as skin, cartilage, dentine, osteoid, and capillary blood vessels. (medscape.com)
  • The most important signs of the deficiency of vitamin C are anorexia, reduction of growth, reduced bone collagen, lordosis, scoliosis, haemorrhagies in the fins and in the internal organs, problems in the gill filaments, erosion of the fins, and increased mortality. (ukessays.com)
  • A distinctive feature of collagen is the regular arrangement of amino acids in each of the three chains of the collagen subunits. (newworldencyclopedia.org)
  • Vitamin C (ascorbic acid) is a water-soluble vitamin, which is needed by the body to form collagen in bones, cartilage, muscle, and blood vessels. (livingnaturally.com)
  • Ascorbic acid ( vitamin C ) is a water-soluble vitamin. (rxlist.com)
  • Vitamin C, or ascorbic acid, is a water-soluble vitamin that is present in large quantities in the body. (gurze.com)
  • L-Ascorbic Acid (Vitamin C) is a water-soluble vitamin that is essential for growth and repair of tissue. (cerilliant.com)
  • A scorbic acid (vitamin C) is the most potent water-soluble antioxidant in biological fluids and is widely distributed across cells/tissues ( 36 ). (pubmedcentralcanada.ca)
  • The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration. (nih.gov)
  • The primary purpose of this study is to evaluate the safety and tolerability of vitamin C (ascorbic acid) given by injection into the vein. (bioportfolio.com)
  • Ascorbic Acid (vitamin c) Injection is a sterile solution. (rxlist.com)
  • Each mL contains: Ascorbic Acid (vitamin c) 250 mg and Edetate Disodium 0.025% in Water for Injection qs. (rxlist.com)
  • Ascorbic Acid (vitamin c) Injection, USP, 250 mg/mL is available in 2 mL ampules, in cartons of 25. (rxlist.com)
  • Animal reproduction studies have not been conducted with Ascorbic Acid Injection. (nih.gov)
  • It is also not known whether Ascorbic Acid Injection can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. (nih.gov)
  • Ascorbic Acid Injection should be given to a pregnant woman only if clearly needed. (nih.gov)
  • Caution should be exercised when Ascorbic Acid Injection is administered to a nursing woman. (nih.gov)
  • Ascorbic acid is administered by injection in severe deficiency states and where persistent vomiting, diarrhoea or other conditions prevent adequate utilisation by mouth. (intekom.com)
  • Higher infectivity and mortality rates and a more severe type of disease were encountered in guinea-pigs fed a purified diet deficient in ascorbic acid than in those on the same diet with an adequate supplement of this vitamin. (ajtmh.org)
  • Plasma ascorbic acid was low (less than 23 mu mol/L) in 11 (85%) of the 13 untreated PCT patients and deficient (less than 11 mu mol/L) in 8 (62%), Two patients with normal ascorbic acid levels (45 and 62 mu mmol/L) had consumed multivitamins. (hepcprimer.com)
  • Chemical determinations of ascorbic acid levels in the plasma, muscle, liver and spleen revealed no significant alterations in the distribution of tissue ascorbic acid in infected guinea-pigs. (ajtmh.org)
  • Aims Aldehyde reductase (AKR1A), a member of the aldo-keto reductase superfamily, is highly expressed in the liver and is involved in both the detoxification of carbonyl compounds and ascorbic acid biosynthesis. (elsevier.com)
  • Thus, ascorbic acid also had no effect on the detoxification system in the liver. (elsevier.com)
  • The dietary survey of vegetarian mothers revealed that their diet was lacking in ascorbic acid as the consumption of fruits and citrus fruits was meagre (5) . (whale.to)
  • Ascorbic acid (vitamin C) occurs naturally in foods such as citrus fruit, tomatoes, potatoes, and leafy vegetables. (wellspan.org)
  • Consuming citrus fruits, like lemons, will prevent vitamin C deficiency. (wisegeek.com)
  • In the United States, hemolysis induced by infection or drugs is the most common clinical manifestation of G-6-PD deficiency (2). (annals.org)
  • This certified solution standard is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in HPLC /UV or electrochemical (EC) L-ascorbic acid clinical or dietary supplement testing applications. (cerilliant.com)
  • Clinical testing of L-ascorbic acid levels is performed to evaluate vitamin C deficiency. (cerilliant.com)
  • Therefore, working to reduce the postoperative mortality due to respiratory involvement, we have given ascorbic acid to those patients who, postoperatively, showed clinical signs of moisture in the lungs with sometimes patches of consolidation, accompanied by a rise in temperature and respiratory rate. (whale.to)
  • Cham B.E., Roeser H.P. and Nikles A.C. (1990) Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea pigs. (edu.au)
  • [ 7 ] The enzyme L-gluconolactone oxidase, which would usually catalyze the conversion of L-gluconogammalactone to L-ascorbic acid, is defective due to a mutation or inborn error in carbohydrate metabolism. (medscape.com)
  • The recommended dietary allowance of vitamin C (ascorbic acid) increases with age. (wellspan.org)
  • Excess amounts of ascorbic acid are excreted unchanged or as metabolites. (medscape.com)
  • The explanations for this difference probably lie in the timing of the vitamin C dose in relation to the serum iron measurement and the fact that the majority of the subjects in the present study did not have iron overload or ascorbic acid deficiency of the severity described by Wapnick et al. (freethesaurus.com)
  • We measured some haematological and biochemical parameters to establish any correlation between serum ascorbic acid and iron and thus open study line on the need for co-supplementation of the two during antenatal visits to prevent iron-deficiency anaemia in pregnancy. (biomedres.info)
  • Blood sample collected from each subject was analyzed for hematological (haemoglobin-Hb, packed cell volume-PCV and mean cell haemoglobin concentration-MCHC) and biochemical (serum iron and ascorbic acid) parameters. (biomedres.info)
  • 0.05) between the serum iron and ascorbic acid in the first and second trimesters and the control group. (biomedres.info)
  • The following estimations were performed on both the samples immediately after the collection - blood hemoglobin (Hb) (cyanmethemoglobin method), serum iron (8) , total iron binding capacity (TIBC) (8) , percent saturation (PS), (by calculation), serum ferritin (9) , serum copper (10) , total proteins (11) and ascorbic acid (12) . (whale.to)
  • Plasma total ascorbic acid concentrations were measured using a colorimetric method involving a reaction between ascorbic acid, 2,6 dichlorophenol-indophenol, thiourea and dinitrophenyl hydrazine. (wiley.com)
  • An estimated 25% of British men and 16% of women on low incomes have blood vitamin C concentrations indicative of deficiency, and a further fifth of the population have levels in the depleted range. (theconversation.com)
  • Protein Soy, fish, chicken, turkey, eggs, pork, extract, and cheese are examples of proteins that seat adequate principal amino acids to quicken protein fusion and that being the case game reserve muscle mass. (bonetumor.org)
  • It is characterized by the regular arrangement of amino acids in each of the three chains, with regular repetition and high glycine content-with glycine found at almost every third residue. (newworldencyclopedia.org)
  • There are two uncommon derivative amino acids not directly inserted during translation of mRNA . (newworldencyclopedia.org)
  • Besides containing a fairly low concentration of protein to begin with, they also don't contain a good balance of essential amino acids. (blogspot.com)
  • This prevents their efficient use by the body, unless a separate source of certain amino acids is eaten along with them. (blogspot.com)
  • Bacterial fermentation produces lysine, often increasing its concentration by many fold and making grains nearly a "complete protein", i.e. one that contains the ideal balance of essential amino acids as do animal proteins ( 11 , scroll down to see graph). (blogspot.com)
  • The ICD-10 code range for ICD-10 Other nutritional deficiencies E50-E64 is medical classification list by the World Health Organization (WHO). (aapc.com)
  • See 21 Hidden Clues to Diagnosing Nutritional Deficiencies , a Critical Images slideshow, to help identify clues to conditions associated with malnutrition. (medscape.com)
  • Nutritional deficiencies are rarely reported in developed countries. (worldwidescience.org)
  • Ascorbic acid is used to treat and prevent vitamin C deficiency. (everydayhealth.com)
  • It is used to treat or prevent vitamin C deficiency. (drugs.com)
  • Older adults are at the highest risk for vitamin C deficiency, since they're most likely to suffer from poor nutrition. (3fatchicks.com)
  • The elderly often suffer from Vitamin C deficiency, so should make sure they eat a balanced diet. (wisegeek.com)
  • Hemodialysis (HD) patients with functional iron deficiency (FID) often develop resistance to recombinant human erythropoietin (rHuEpo). (drcalapai.net)
  • The most important factors known to be associated with this condition are socio-economic status, poor diet, poor sanitation and various infections and infestations .Anaemia in pregnancy is defined as a haemoglobin level of less than 11.0g/dl and iron-deficiency contributes significantly to this, especially among women of south eastern Nigeria [3]. (indmedica.com)
  • Iron-deficiency anaemia is one of the direct and indirect causes of maternal mortality and can only be arrested by early detection and management during antenatal visits. (indmedica.com)
  • Complications of iron-deficiency anaemia in pregnancy include, among others, impaired oxygen transport (leading to hypoxia) and abnormal basic cell functions. (indmedica.com)
  • Ascorbic acid and iron polysaccharide may also be used for purposes not listed in this medication guide. (everydayhealth.com)
  • Do not take more ascorbic acid and iron polysaccharide than is prescribed for you or than is directed on the package. (everydayhealth.com)
  • Talk to your doctor and pharmacist before taking ascorbic acid and iron polysaccharide if you take any other prescription or over-the-counter medicines. (everydayhealth.com)
  • If you do not have an iron deficiency, talk to your doctor about the use of ascorbic acid and iron polysaccharide. (everydayhealth.com)
  • Generally, ascorbic acid and iron polysaccharide should not be taken chronically by individuals with a normal iron balance. (everydayhealth.com)
  • FDA pregnancy category C. It is not known whether ascorbic acid and iron polysaccharide will harm an unborn baby. (everydayhealth.com)
  • It is not known whether ascorbic acid and iron polysaccharide passes into breast milk or if it could harm a nursing baby. (everydayhealth.com)
  • This list is not complete and other drugs may interact with ascorbic acid and iron polysaccharide. (everydayhealth.com)
  • Results of tests for glycosuria, uric acid, and iron may be inaccurate when the patient is receiving large amounts of the vitamin. (thefreedictionary.com)
  • One of the commonest food myths is that vegetarians and vegans have a higher risk of iron deficiency anaemia because they don't eat meat. (scribd.com)
  • tell your doctor and pharmacist if you are allergic to ascorbic acid, any other medications, or any of the ingredients in ascorbic acid products. (medlineplus.gov)
  • However, starting vitamin C supplementation when you feel a cold coming on may be significantly less helpful than regular inclusion of the acid in your diet. (organicfacts.net)
  • Associate Professor Mark Bolland and colleagues at the University of Auckland, New Zealand and the University of Aberdeen, Scotland say those at high risk of vitamin D deficiency should be advised about sunlight exposure and diet and offered low dose supplements, but the rest of us should focus on eating a healthy balanced diet with food containing vitamin D and getting regular short bursts of sunshine. (medindia.net)
  • Poor diet is the primary cause of vitamin C deficiency. (3fatchicks.com)
  • Ascorbic acid (vitamin C) is used as a dietary supplement when the amount of ascorbic acid in the diet is not enough. (medlineplus.gov)
  • People most at risk for ascorbic acid deficiency are those with a limited variety of food in their diet, or who have intestinal malabsorption problems from cancer or kidney disease. (medlineplus.gov)
  • A nutritional condition produced by a deficiency of VITAMIN K in the diet, characterized by an increased tendency to hemorrhage (HEMORRHAGIC DISORDERS). (mcw.edu)
  • Iodine deficiency during pregnancy results in cretinism and possible fetal wastage and preterm delivery. (slideshare.net)
  • Deficiency of other minerals such as magnesium, selenium, copper, and calcium has also been associated with complications of pregnancy, childbirth or fetal development. (slideshare.net)
  • Animal studies have shown that vitamin C deficiency in a woman during pregnancy can lead to problems with fetal brain development. (medicalnewstoday.com)
  • Solutions of ascorbic acid deteriorate rapidly, and it is not stored in the body to any extent. (thefreedictionary.com)
  • Under the right conditions, which are easy to achieve, lactic acid bacteria rapidly acidify the batter. (blogspot.com)
  • Continuous blue lighting and elevated carbon dioxide concentration rapidly increase chlorogenic acid content in young lettuce plants. (researchmap.jp)
  • In 1928, when Albert Szent-Gyorgyi isolated the active ingredient, he called it the anti-scorbutic principle, or ascorbic acid. (memorialhospitaljax.com)
  • A child presenting a "scorbutic tongue" due to vitamin C deficiency. (wikipedia.org)
  • According to new studies up to three quarters of elderly in India have vitamin C deficiency due to poor dietary habits, smoking and consumption of tobacco. (medindia.net)
  • Those who eat plenty of fruits and vegetables shouldn't worry about vitamin C deficiency. (3fatchicks.com)
  • Dietary ascorbic acid, or vitamin C, is plentiful in a number of fruits and vegetables. (3fatchicks.com)
  • Consumption of fruits and vegetables or diets fortified with vitamin C is essential to avoid ascorbic acid deficiency. (medscape.com)
  • This is supported by the fact that despite the national policy that pregnant women in all trimesters should be prescribed ferrous sulphate (200mg) with folic acid (5mg) daily from the day of first visit to the antenatal clinic to the day of delivery [8], there is still increasing cases of anaemia in pregnancy. (indmedica.com)
  • Folic acid deficiency can lead to hematological consequences, pregnancy complications and congenital malformations, but again the association with other birth outcomes is equivocal. (slideshare.net)
  • Note the perifollicular purpura and the corkscrew hairs characteristic of severe vitamin C deficiency in this patient on chronic total parenteral nutrition. (renalandurologynews.com)
  • Severe vitamin C deficiency is usually defined as a deficiency that has gone on for months or even years at a time. (wisegeek.com)
  • Though the origins of erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) deficiency are rooted in human antiquity, the presence of drug-induced hemolysis in individuals subsequently felt to have G-6-PD deficiency was first reported in 1926 and the biochemical lesion responsible for this phenomenon elucidated in 1956 (1). (annals.org)
  • Electrochemical behavior of ascorbic acid at a 2,2'-[3,6-Dioxa-1,8-octanediylbis(nitriloethylidyne)]-bis-hydroquinone carbon paste electrode. (biomedsearch.com)
  • Vitamin C, also known as ascorbic acid and L-ascorbic acid, is a vitamin found in food and used as a dietary supplement. (giantmicrobes.com)
  • l -ascorbic acid , is a vitamin found in various foods and sold as a dietary supplement . (wikipedia.org)
  • Zinc deficiency has been associated in some, but not all studies with complications of pregnancy and delivery, as well as with growth retardation,congenital abnormalities and retarded neurobehavioral and immunological development in the fetus. (slideshare.net)
  • Ascorbic acid comes in extended-release (long-acting) capsules and tablets, lozenges, chewable tablets, chewable gels (gummies), and liquid drops to be given by mouth. (medlineplus.gov)
  • If you have an allergy to ascorbic acid or any other part of this medicine (ascorbic acid capsules and tablets). (drugs.com)
  • You must check to make sure that it is safe for you to take this medicine (ascorbic acid capsules and tablets) with all of your drugs and health problems. (drugs.com)
  • Tell all of your health care providers that you take this medicine (ascorbic acid capsules and tablets). (drugs.com)
  • Do not take this medicine (ascorbic acid capsules and tablets) for longer than you were told by your doctor. (drugs.com)
  • You will need to talk about the benefits and risks of using this medicine (ascorbic acid capsules and tablets) while you are pregnant. (drugs.com)
  • How is this medicine (Ascorbic Acid Capsules and Tablets) best taken? (drugs.com)
  • Use this medicine (ascorbic acid capsules and tablets) as ordered by your doctor. (drugs.com)
  • Keep taking this medicine (ascorbic acid capsules and tablets) as you have been told by your doctor or other health care provider, even if you feel well. (drugs.com)