Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.Ascorbic Acid Deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)Dehydroascorbic Acid: The reversibly oxidized form of ascorbic acid. It is the lactone of 2,3-DIKETOGULONIC ACID and has antiscorbutic activity in man on oral ingestion.Scurvy: An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. Scurvy is characterized by bleeding in any tissue, weakness, ANEMIA, spongy gums, and a brawny induration of the muscles of the calves and legs.Antioxidants: Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.L-Gulonolactone Oxidase: An enzyme involved in the metabolism of ASCORBIC ACID and aldarate. It catalyzes the oxidation of L-gulono-1,4-lactone to L-xylo-hex-3-ulonolactone.Sodium-Coupled Vitamin C Transporters: Membrane transport proteins that actively co-transport ASCORBIC ACID and sodium ions across the CELL MEMBRANE. Dietary absorption of VITAMIN C is highly dependent upon this class of transporters and a subset of SODIUM GLUCOSE TRANSPORTERS which transport the oxidized form of vitamin C, DEHYDROASCORBIC ACID.Ascorbate Oxidase: An enzyme that converts ascorbic acid to dehydroascorbic acid. EC 1.10.3.3.2,3-Diketogulonic Acid: Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Rats, Mutant Strains: Rats bearing mutant genes which are phenotypically expressed in the animals.Free Radical Scavengers: Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.Glutathione: A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.Phosphorous Acids: Inorganic derivatives of phosphorus trihydroxide (P(OH)3) and its tautomeric form dihydroxyphosphine oxide (HP=O(OH)2). Note that organic derivatives of phosphonic acids are listed under are ORGANOPHOSPHONATES.Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.PicratesVitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.alpha-Tocopherol: A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.Lipid Peroxidation: Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor.Chromaffin Granules: Organelles in CHROMAFFIN CELLS located in the adrenal glands and various other organs. These granules are the site of the synthesis, storage, metabolism, and secretion of EPINEPHRINE and NOREPINEPHRINE.Diet: Regular course of eating and drinking adopted by a person or animal.Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.Ferrous Compounds: Inorganic or organic compounds that contain divalent iron.Lipid Peroxides: Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin E, structural separation or low oxygen tension.Free Radicals: Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.Biological Availability: The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.Electrodes: Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.Electrochemistry: The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.Oxidative Stress: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Copper: A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.Chromaffin System: The cells of the body which stain with chromium salts. They occur along the sympathetic nerves, in the adrenal gland, and in various other organs.Malondialdehyde: The dialdehyde of malonic acid.Rutin: A flavonol glycoside found in many plants, including BUCKWHEAT; TOBACCO; FORSYTHIA; HYDRANGEA; VIOLA, etc. It has been used therapeutically to decrease capillary fragility.Chlorobutanol: A colorless to white crystalline compound with a camphoraceous odor and taste. It is a widely used preservative in various pharmaceutical solutions, especially injectables. Also, it is an active ingredient in certain oral sedatives and topical anesthetics.Thiobarbiturates: Compounds in which one or more of the ketone groups on the pyrimidine ring of barbituric acid are replaced by thione groups.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Vitamins: Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.Hydrogen Peroxide: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Food, Fortified: Any food that has been supplemented with essential nutrients either in quantities that are greater than those present normally, or which are not present in the food normally. Fortified food includes also food to which various nutrients have been added to compensate for those removed by refinement or processing. (From Segen, Dictionary of Modern Medicine, 1992)Malpighiaceae: A plant family of the order Polygalales, subclass Rosidae class, Magnoliopsida that are mostly shrubs and small trees. Many of the members contain indole alkaloids.Organic Anion Transporters, Sodium-Dependent: A subclass of ORGANIC ANION TRANSPORTERS whose transport of organic anions is driven either directly or indirectly by a gradient of sodium ions.Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.Sugar Alcohol Dehydrogenases: Reversibly catalyzes the oxidation of a hydroxyl group of sugar alcohols to form a keto sugar, aldehyde or lactone. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.; EC 1.1.2. and EC 1.1.99.Iron, Dietary: Iron or iron compounds used in foods or as food. Dietary iron is important in oxygen transport and the synthesis of the iron-porphyrin proteins hemoglobin, myoglobin, cytochromes, and cytochrome oxidase. Insufficient amounts of dietary iron can lead to iron-deficiency anemia.Kinetics: The rate dynamics in chemical or physical systems.Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Aniline Hydroxylase: A drug-metabolizing, cytochrome P-450 enzyme which catalyzes the hydroxylation of aniline to hydroxyaniline in the presence of reduced flavoprotein and molecular oxygen. EC 1.14.14.-.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Peroxides: A group of compounds that contain a bivalent O-O group, i.e., the oxygen atoms are univalent. They can either be inorganic or organic in nature. Such compounds release atomic (nascent) oxygen readily. Thus they are strong oxidizing agents and fire hazards when in contact with combustible materials, especially under high-temperature conditions. The chief industrial uses of peroxides are as oxidizing agents, bleaching agents, and initiators of polymerization. (From Hawley's Condensed Chemical Dictionary, 11th ed)Dopamine beta-HydroxylaseAdrenal Medulla: The inner portion of the adrenal gland. Derived from ECTODERM, adrenal medulla consists mainly of CHROMAFFIN CELLS that produces and stores a number of NEUROTRANSMITTERS, mainly adrenaline (EPINEPHRINE) and NOREPINEPHRINE. The activity of the adrenal medulla is regulated by the SYMPATHETIC NERVOUS SYSTEM.Thiobarbituric Acid Reactive Substances: Low-molecular-weight end products, probably malondialdehyde, that are formed during the decomposition of lipid peroxidation products. These compounds react with thiobarbituric acid to form a fluorescent red adduct.PhenylenediaminesTime Factors: Elements of limited time intervals, contributing to particular results or situations.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Fruit: The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.Oxalates: Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure.Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.Pharmaceutical Solutions: Homogeneous liquid preparations that contain one or more chemical substances dissolved, i.e., molecularly dispersed, in a suitable solvent or mixture of mutually miscible solvents. For reasons of their ingredients, method of preparation, or use, they do not fall into another group of products.

Double-blind intervention trial on modulation of ozone effects on pulmonary function by antioxidant supplements. (1/4830)

The aim of this study was to investigate whether the acute effects of ozone on lung function could be modulated by antioxidant vitamin supplementation in a placebo-controlled study. Lung function was measured in Dutch bicyclists (n = 38) before and after each training session on a number of occasions (n = 380) during the summer of 1996. The vitamin group (n = 20) received 100 mg of vitamin E and 500 mg of vitamin C daily for 15 weeks. The average ozone concentration during exercise was 77 microg/m3 (range, 14-186 microg/m3). After exclusion of subjects with insufficient compliance from the analysis, a difference in ozone exposure of 100 microg/m3 decreased forced expiratory volume in 1 second (FEV1) 95 ml (95% confidence interval (CI) -265 to -53) in the placebo group and 1 ml (95% CI -94 to 132) in the vitamin group; for forced vital capacity, the change was -125 ml (95% CI -384 to -36) in the placebo group and -42 ml (95% CI -130 to 35) in the vitamin group. The differences in ozone effect on lung function between the groups were statistically significant. The results suggest that supplementation with the antioxidant vitamins C and E confers partial protection against the acute effects of ozone on FEV1 and forced vital capacity in cyclists.  (+info)

Thiol-dependent degradation of protoporphyrin IX by plant peroxidases. (2/4830)

Protoporphyrin IX (PP) is the last porphyrin intermediate in common between heme and chlorophyll biosynthesis. This pigment normally does not accumulate in plants because its highly photodynamic nature makes it toxic. While the steps leading to heme and chlorophylls are well characterized, relatively little is known of the metabolic fate of excess PP in plants. We have discovered that plant peroxidases can rapidly degrade this pigment in the presence of thiol-containing substrates such as glutathione and cysteine. This thiol-dependent degradation of PP by horseradish peroxidase consumes oxygen and is inhibited by ascorbic acid.  (+info)

Stabilization of L-ascorbic acid by superoxide dismutase and catalase. (3/4830)

The effects of superoxide dismutase (SOD) and catalase on the autoxidation rate of L-ascorbic acid (ASA) in the absence of metal ion catalysts were examined. The stabilization of ASA by SOD was confirmed, and the enzyme activity of SOD, which scavenges the superoxide anion formed during the autoxidation of ASA, contributed strongly to this stabilization. The stabilization of ASA by catalase was observed for the first time; however, the specific enzyme ability of catalase would not have been involved in the stabilization of ASA. Such proteins as bovine serum albumin (BSA) and ovalbumin also inhibited the autoxidation of ASA, therefore it seems that non-specific interaction between ASA and such proteins as catalase and BSA might stabilize ASA and that the non-enzymatic superoxide anion scavenging ability of proteins might be involved.  (+info)

Glutathione-S-transferase (GSTM1) genetic polymorphisms do not affect human breast cancer risk, regardless of dietary antioxidants. (4/4830)

Glutathione-S-transferases catalyze the detoxication of carcinogen metabolites and reactive oxygen species (ROS) produced through a number of mechanisms. Glutathione-S-transferase (GST) M1 is polymorphic, and the null allele results in a lack of enzyme activity. Because there are indications that ROS may be involved in breast carcinogenesis, we sought to determine whether the GSTM1 null allele was associated with increased breast cancer, particularly among women with lower consumption of dietary sources of alpha-tocopherol, carotenoids and ascorbic acid. In a study of diet and cancer in western New York, women with primary, incident, histologically confirmed breast cancer (n = 740) and community controls (n = 810) were interviewed and an extensive food-frequency questionnaire administered. A subset of these women provided a blood specimen. DNA was extracted and genotyping performed for GSTM1. Data were available for 279 cases and 340 controls. The null allele did not increase breast cancer risk, regardless of menopausal status. There were also no differences in associations between the polymorphism and risk among lower and higher consumers of dietary sources of antioxidants or smokers and nonsmokers. These results indicate that GSTM1 genetic polymorphisms are not associated with breast cancer risk, even in an environment low in antioxidant defenses.  (+info)

Prospective cohort study of antioxidant vitamin supplement use and the risk of age-related maculopathy. (5/4830)

In a prospective cohort study, the authors examined whether self-selection for antioxidant vitamin supplement use affects the incidence of age-related maculopathy. The study population consisted of 21,120 US male physician participants in the Physicians' Health Study I who did not have a diagnosis of age-related maculopathy at baseline (1982). During an average of 12.5 person-years of follow-up, a total of 279 incident cases of age-related maculopathy with vision loss to 20/30 or worse were confirmed by medical record review. In multivariate analysis, as compared with nonusers of supplements, persons who used vitamin E supplements had a possible but nonsignificant 13% reduced risk of age-related maculopathy (relative risk = 0.87, 95 percent confidence interval (CI) 0.53-1.43), while users of multivitamins had a possible but nonsignificant 10% reduced risk (relative risk = 0.90, 95% CI 0.68-1.19). Users of vitamin C supplements had a relative risk of 1.03 (95% CI 0.71-1.50). These observational data suggest that among persons who self-select for supplemental use of antioxidant vitamin C or E or multivitamins, large reductions in the risk of age-related maculopathy are unlikely. Randomized trial data are accumulating to enable reliable detection of the existence of more plausible small-to-moderate benefits of these agents alone and in combination on age-related maculopathy.  (+info)

Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. (6/4830)

BACKGROUND: Hyperhomocysteinemia is a major and independent risk factor for vascular disease. The mechanisms by which homocysteine promotes atherosclerosis are not well understood. We hypothesized that elevated homocysteine concentrations are associated with rapid onset endothelial dysfunction, which is mediated through oxidant stress mechanisms and can be inhibited by the antioxidant vitamin C. METHODS AND RESULTS: We studied 17 healthy volunteers (10 male and 7 female) aged 33 (range 21 to 59) years. Brachial artery diameter responses to hyperemic flow (endothelium dependent), and glyceryltrinitrate (GTN, endothelium independent) were measured with high resolution ultrasound at 0 hours (fasting), 2 hours, and 4 hours after (1) oral methionine (L-methionine 100 mg/kg), (2) oral methionine preceded by vitamin C (1g/day, for 1 week), and (3) placebo, on separate days and in random order. Plasma homocysteine increased (0 hours, 12.8+/-1.4; 2 hours, 25.4+/-2.5; and 4 hours, 31. 2+/-3.1 micromol/l, P<0.001), and flow-mediated dilatation fell (0 hours, 4.3+/-0.7; 2 hours, 1.1+/-0.9; and 4 hours, -0.7+/-0.8%) after oral L-methionine. There was an inverse linear relationship between homocysteine concentration and flow-mediated dilatation (P<0. 001). Pretreatment with vitamin C did not affect the rise in homocysteine concentrations after methionine (0 hours, 13.6+/-1.6; 2 hours, 28.3+/-2.9; and 4 hours, 33.8+/-3.7 micromol/l, P=0.27), but did ameliorate the reduction in flow-mediated dilatation (0 hours, 4. 0+/-1.0; 2 hours, 3.5+/-1.2 and 4 hours, 2.8+/-0.7%, P=0.02). GTN-induced endothelium independent brachial artery dilatation was not affected after methionine or methionine preceded by vitamin C. CONCLUSIONS: We conclude that an elevation in homocysteine concentration is associated with an acute impairment of vascular endothelial function that can be prevented by pretreatment with vitamin C in healthy subjects. Our results support the hypothesis that the adverse effects of homocysteine on vascular endothelial cells are mediated through oxidative stress mechanisms.  (+info)

L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells. (7/4830)

Ascorbic acid has been shown to enhance impaired endothelium-dependent vasodilation in patients with atherosclerosis by a mechanism that is thought to involve protection of nitric oxide (NO) from inactivation by free oxygen radicals. The present study in human endothelial cells from umbilical veins and coronary arteries investigates whether L-ascorbic acid additionally affects cellular NO synthesis. Endothelial cells were incubated for 24 h with 0.1-100 microM ascorbic acid and were subsequently stimulated for 15 min with ionomycin (2 microM) or thrombin (1 unit/ml) in the absence of extracellular ascorbate. Ascorbate pretreatment led to a 3-fold increase of the cellular production of NO measured as the formation of its co-product citrulline and as the accumulation of its effector molecule cGMP. The effect was saturated at 100 microM and followed a similar kinetics as seen for the uptake of ascorbate into the cells. The investigation of the precursor molecule L-gulonolactone and of different ascorbic acid derivatives suggests that the enediol structure of ascorbate is essential for its effect on NO synthesis. Ascorbic acid did not induce the expression of the NO synthase (NOS) protein nor enhance the uptake of the NOS substrate L-arginine into endothelial cells. The ascorbic acid effect was minimal when the citrulline formation was measured in cell lysates from ascorbate-pretreated cells in the presence of known cofactors for NOS activity. However, when the cofactor tetrahydrobiopterin was omitted from the assay, a similar potentiating effect of ascorbate pretreatment as seen in intact cells was demonstrated, suggesting that ascorbic acid may either enhance the availability of tetrahydrobiopterin or increase its affinity for the endothelial NOS. Our data suggest that intracellular ascorbic acid enhances NO synthesis in endothelial cells and that this may explain, in part, the beneficial vascular effects of ascorbic acid.  (+info)

Cytotoxic effect of paraquat on rat C6 glioma cells: evidence for the possibility of non-oxidative damage to the cells. (8/4830)

Although paraquat has been shown to cause oxidative damage to neuronal cells, little is known about its effect on glial cells. Thus the effect of paraquat on glial cells was examined using rat C6 glioma cells as a model system. Paraquat reduced cell viability in a concentration- and time-dependent manner, and this toxic effect was not significantly attenuated by various kinds of antioxidants. Furthermore, paraquat failed to increase 8-hydroxy-deoxyguanosine formation in the cells. These results indicate that paraquat can be toxic to glial cells and suggest that this cytotoxic effect may not be associated with the oxidative damage to the cells.  (+info)

*Ascorbic acid (molecular aspects)

... a diastereomer of ascorbic acid. Mineral ascorbates: salts of ascorbic acid Acids in wine Safety (MSDS) data for ascorbic acid ... to produce ascorbic acid. L-Ascorbic acid has a negative feedback on L-galactose dehydrogenase in spinach. Ascorbic acid efflux ... Yeasts do not make L-ascorbic acid but rather its stereoisomer, erythorbic acid Ascorbic acid is prepared in industry from ... xylonic acid, threonic acid and oxalic acid. Ascorbic acid and its sodium, potassium, and calcium salts are commonly used as ...

*Abusive head trauma

Johnston, C.S. (1996). "Chapter 10) The Antihistamine Action of Ascorbic Acid". Ascorbic Acid; Biochemistry and Biomedical Cell ...

*Flour treatment agent

Common oxidizing agents are: ascorbic acid (Ascorbic acid converts into its oxidizing form, dehydroascorbic acid (DHAA) during ... "Ascorbic acid". Sustain. Retrieved 8 July 2014. Tenbergen, Klaus. "Dough and Bread Conditioners". Food and Product Design ... Oxidizing agents primarily affect sulfur-containing amino acids, ultimately helping to form disulfide bridges between the ... fumaric acid sodium bisulfate[citation needed] non-leavening yeast (ruptured cells) Enzymes are also used to improve processing ...

*Vitamin C megadosage

Food portal Ascorbic acid Micronutrient Macronutrient Megavitamin therapy Orthomolecular medicine Uric acid Vitamin Institute ... and acid erosion of the teeth with chewing ascorbic-acid tablets. In addition, one case has been noted of a woman who had ... More recently, in vitro data in animal models suggests intravenous ascorbic acid at high doses may hold some promise in the ... "Vitamin C (Ascorbic Acid)". University of Maryland Medical Center. April 2002. Retrieved 2007-02-19. Pauling L (1970). " ...

*Alan Clemetson

Histamine and ascorbic acid in human blood. J. Nutr. 110:662-668. Biologic Markers in Reproductive Toxicology (1989) "Cell ... Clemetson CA (1976). "Ascorbic acid and diabetes mellitus". Medical Hypotheses. 2 (5): 193-4. doi:10.1016/0306-9877(76)90037-2 ... Clemetson CA (1 April 1980). "Histamine and ascorbic acid in human blood". Journal of Nutrition. 110 (4): 662-8. PMID 7365537. ... doi:10.1016/s0010-7824(71)80004-5. Saroja N, Mallikarjuneswara VR, Clemetson CA (1971). "Effect of estrogens on ascorbic acid ...

*P. Brahmayya Sastry

Ascorbic acid and melanogenesis. Br J Dermatol. 1977 Aug;97(2):201-4. 8. Reddi YV, Sastry PB, Ramadas G. The effects of excess ...

*Complications of diabetes mellitus

Antioxidants: Three vitamins, ascorbic acid; α-tocopherol; and β-carotene, are well recognized for their antioxidant activities ... CS1 maint: Multiple names: authors list (link) Mullan B. A.; Young I. S.; Fee H.; McCance D. R. (2002). "Ascorbic acid reduces ... Folic acid: Low plasma concentrations of folic acid were found to be associated with high plasma homocysteine concentrations. ... van Etten et al., found that a single dose of folic acid might help in reducing the risk of vascular complications and ...

*Vitamin C and the common cold

Manwaring WH (1945). "Ascorbic Acid vs. the Common Cold". Cal West Med. 62 (6): 309-10. PMC 1781017 . PMID 18747053. Hemilä H ( ...

*Threonic acid

... is a sugar acid derived from threose. The L-isomer is a metabolite of ascorbic acid (vitamin C). One study ... S Englard and S Seifter (1986). "The Biochemical Functions of Ascorbic Acid". Annual Review of Nutrition. 6: 365-406. doi: ...

*Median lethal dose

"Safety (MSDS) data for ascorbic acid". Oxford University. 2005-10-09. Archived from the original on 2007-02-09. Retrieved 2007- ... Handbook of Mushroom Poisoning Safety (MSDS) data for hydrochloric acid Ketamine Safety (MSDS) data for acetylsalicylic acid ... A.A. Babayan, A.V.Aleksandryan, "Toxicological characteristics of melamine cyanurate, melamine and cyanuric acid", Zhurnal ... Acid) Vault : Fatalities / Deaths. Erowid.org. Retrieved on 2013-07-17. Safety (MSDS) data for arsenic trioxide Safety (MSDS) ...

*Nitrosamine

"Dietary phenolic acids and ascorbic acid: Influence on acid-catalyzed nitrosative chemistry in the presence and absence of ... "Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation". Gut. 56 (12): 1678-84. doi:10.1136/gut ... Evidence now exists that ascorbic acid is a limiting factor in nitrosation reactions in people. Combet, E; Paterson, S; Iijima ... There are also rules about adding ascorbic acid or related compounds to meat, as the compounds inhibit formation of ...

*Solute carrier family

Takanaga H, Mackenzie B, Hediger MA (2004). "Sodium-dependent ascorbic acid transporter family SLC23". Pflugers Arch. 447 (5): ... Na+-dependent ascorbic acid transporter(SLC23A1, SLC23A2, SLC23A3, SLC23A4) (24) Na+/(Ca2+-K+) exchanger(SLC24A1, SLC24A2, ... cationic amino acid transporter/glycoprotein-associatedcationic amino acid transporters (SLC7A1, SLC7A2, SLC7A3, SLC7A4) ... Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y (2004). "CATs and HATs: the SLC7 family of amino acid transporters ...

*Synzyme

Ascorbic acid is oxidised with molecular oxygen. Antibodies can act as enzymes, then named abzymes, if they are selected ...

*Orthomolecular medicine

Ohno, S; Ohno, Y; Suzuki, N; Soma, G; Inoue, M (2009). "High-dose vitamin C (ascorbic acid) therapy in the treatment of ... amino acids, ω-3 fatty acids, ω-6 fatty acids, medium-chain triglycerides, dietary fiber, short and long chain fatty acids, ... Klenner FR (1971). "Observations on the dose and administration of ascorbic acid when employed beyond the range of a vitamin in ... 1998). "Observations on the dose and administration of ascorbic acid when employed beyond the range of a vitamin in human ...

*Dough

"How Is Ascorbic Acid Used in Food?". LIVESTRONG.COM. Retrieved 2017-07-28. "Ascorbic Acid and its Use in Food". The Spruce. ... Ascorbic acid, otherwise known as vitamin C, is used as an antioxidant in dough. By controlling the amount of oxygen reacting ... L-cysteine is a non-essential amino acid that the human body can obtain by converting the essential amino acid methionine. It ... L-cysteine hydrochloride is a non-essential amino acid formed by the body and is used in the baking industry as a dough ...

*Mineral ascorbates

... the anion of ascorbic acid). Mineral ascorbates are powders manufactured by reacting ascorbic acid with mineral carbonates in ... Mineral ascorbates are a group of salts of ascorbic acid (vitamin C). They are composed of a mineral cation bonded to ascorbate ... Ascorbate salts may be better tolerated by the human body than the corresponding weakly acidic ascorbic acid. Ascorbates are ... Vitamin C Ascorbic acid Ascorbyl palmitate Ascorbyl stearate. ...

*Vanadyl perchlorate

Kustin, Kenneth; Toppen, David L. (June 1973). "Reduction of vanadium(V) by L-ascorbic acid". Inorganic Chemistry. 12 (6): 1404 ... A solution of vanadium(V) perchlorate can be made by dissolving vanadium pentoxide in perchloric acid. Pervanadyl perchlorate ...

*Glucuronolactone reductase

Suzuki K, Mano Y, Shimazono N (1960). "Conversion of L-gulonolactone to L-ascorbic acid; properties of the microsomal enzyme in ...

*SLC23A1

Wang Y, Mackenzie B, Tsukaguchi H, Weremowicz S, Morton CC, Hediger MA (January 2000). "Human vitamin C (L-ascorbic acid) ... "Up-regulation and polarized expression of the sodium-ascorbic acid transporter SVCT1 in post-confluent differentiated CaCo-2 ... "A family of mammalian Na+-dependent L-ascorbic acid transporters". Nature. 399 (6731): 70-5. doi:10.1038/19986. PMID 10331392 ...

*List of dopaminergic drugs

... folic acid → tetrahydrofolic acid) • Vitamin C (ascorbic acid) • Zinc (Zn2+) Benzofuranylpropylaminopentane (BPAP) • ... Fusaric acid • Nepicastat • Phenopicolinic acid • Tropolone L-Phenylalanine → L-tyrosine → L-DOPA (levodopa) Ferrous iron (Fe2+ ... Amfonelic acid • Amineptine • Benzatropine (benztropine) • Bromantane • 2-Butyl-3-(p-tolyl)quinuclidine (BTQ) • BTS-74,398 • ... Lysergic acid diethylamide (LSD) • Pergolide Dihydrexidine derivatives: 2-OH-NPA • A-86,929 • Ciladopa • Dihydrexidine • ...

*Dermatographic urticaria

Johnston, C. S.; Martin, L. J.; Cai, X. (1992-04-01). "Antihistamine effect of supplemental ascorbic acid and neutrophil ...

*Monotreme

L-ascorbic acid is synthesized only in the kidneys. The monotremes also have extra bones in the shoulder girdle, including an ... Ascorbic acid biosynthesis in the mammalian kidney Myers, Pz. "Interpreting Shared Characteristics: The Platypus Genome." ...

*Dough conditioner

"Ascorbic Acid as an Oxidant in Wheat Flour Dough. I. Conversion to Dehydroascorbic Acid" (PDF). Cereal Chemistry. 57 (2): 85-87 ... Elkassabany, M.; Hoseney, R.C. (1980). "Ascorbic Acid as an Oxidant in Wheat Flour Dough. II. Rheological Effects" (PDF). ... Potassium bromate acts more directly or with fewer chemical conversion steps than ascorbic acid. Glutathione increases wheat ... Examples of dough conditioners include ascorbic acid, distilled monoglycerides, citrate ester of monoglycerides, diglycerides, ...

*Euterpe (plant)

... ascorbic acid fortification and storage". Food Research International. 40 (5): 620-628. doi:10.1016/j.foodres.2006.11.006. WCSP ...

*Tetrahydrobiopterin

Ascorbic acid is oxidized to dehydroascorbic acid during this process, although it can be recycled back to ascorbic acid. Other ... Muller-Delp, J. M. (2009). "Ascorbic acid and tetrahydrobiopterin: looking beyond nitric oxide bioavailability". Cardiovascular ... Research shows that ascorbic acid (also known as ascorbate or vitamin C) is effective at recycling BH3 into BH4, preventing the ... Ascorbic Acid, and Thiols: Implications For Uncoupling Endothelial Nitric-Oxide Synthase". Journal of Biological Chemistry. 278 ...

*List of food additives

Pantothenic acid) - Vitamin B6 (Pyrodoxine) - Vitamin B12 (Cyanocobalamin) - Vitamin C (Ascorbic acid) - Vitamin D (Calciferol ... Common food acids include vinegar, citric acid, tartaric acid, malic acid, fumaric acid, and lactic acid. Acidity regulators ... Citranaxanthin - color Citric acid - food acid Citric acid esters of mono- and diglycerides of fatty acids - emulsifier Citrus ... Phosphated distarch phosphate - thickener, vegetable gum Phosphoric acid - food acid Phytic acid - preservative Pigment Rubine ...
To the best of our knowledge, this is the first prospective cohort study to examine the relationship between serum vitamin C concentration and the incidence of stroke. Compared with previous cohort studies based on mortality data,6 10 our study based on incidence data may have some advantages, such as the relatively accurate diagnosis of disease outcomes and the inclusion of nonfatal cases. Serum vitamin C concentration was inversely associated with the subsequent incidence of all stroke during the 20-year observation period. Although a previous study that examined the association between plasma vitamin C concentration and stroke mortality6 had a potential weakness that arose from generally known inaccuracies in death certification, particularly in elderly people,6 our similar results based on incidence data would support their findings and emphasize the importance of the serum (or plasma) vitamin C concentration in predicting the occurrence of stroke.. Most interestingly, an inverse association ...
BACKGROUND: Some studies have hypothesized the protective role of Vitamin C against cardiovascular disorders (CVD) in patients with end-stage renal disease (ESRD). This study was designed to assess plasma Vitamin C concentration and its relationship to hemodialysis (HD) patients morbidity and mortality. METHODS: Plasma Vitamin C concentrations were assessed in HD patients using spectrophotometry and subjects were prospectively followed for up eighteen months for all-cause mortality. Any association between Vitamin C concentration and patients demographic data, co-morbidities, or the cause of ESRD were investigated using the Chi-square test. RESULTS: Ninety-one patients with a mean age of 56.7 ? 15.7 years were included in this study. The most frequent cause of ESRD was simultaneous hypertension and diabetes in 30 % of patients, followed by hypertension in 25.6 %, and diabetes in 11.1 %, respectively. About 34 % of patients had CVD as the most prevalent co-morbidity. Forty-nine patients (53.8 ...
Exercise induces a multitude of physiological and biochemical changes in blood affecting its redox status. Tissue damage resulting from exercise induces activation of inflammatory cells followed by the increased activity of myeloperoxidase (MPO) in circulation. Vitamin C readily scavenges free radicals and may thereby prevent oxidative damage of important biological macromolecules. The aim of this study was to examine the effect of vitamin C supplementation on oxidative stress and neutrophil inflammatory response induced by acute and regular exercise. Experiment was conducted on acute exercise group (performing Bruce Treadmill Protocol (BTP)) and regular training group. Markers of lipid peroxidation, malondialdehyde (MDA), MPO activity, and vitamin C status were estimated at rest and after BTP (acute exercise group) and before and after vitamin C supplementation in both groups. Our results showed increased postexercise Asc in serum independently of vitamin supplementation. They also showed that vitamin
Background: Reactive Oxygen species induced bronchial abnormalities may have important consequences in asthma, the main symptom being wheezing specially in children. Vitamin C is an important antioxidant known to quench the reactive oxygen species. A beneficial effect of fresh fruit consumption on lung function has been observed in several studies. Plasma levels Vitamin C was determined in relation to wheezing symptoms in cross sectional study. Methods: In a cross sectional blood samples of 50 patients attending pediatrics OPD, having wheezing and shortness of breath were analyzed for plasma Ascorbic acid level and compared with healthy controls of same age and sex. Results: The total number of 50 wheezing children were in the age group of 2 to 12 years with similar age matched controls. It was observed that the plasma ascorbic acid concentration in the wheezing children (0.43 - 0.12 mg/dl) was significantly decreased as compared to the normal controls ( 0.75 - 0.18 mg/dl ) P, 0.001. The highly ...
TY - JOUR. T1 - Effect of ascorbic acid administration in hemodialysis patients on in vitro oxidative stress parameters. T2 - Influence of serum ferritin levels. AU - Chen, Wei Teing. AU - Lin, Yuh Feng. AU - Yu, Fu Chiu. AU - Kao, Woei Yau. AU - Huang, Wen Hsin. AU - Yan, Horng Chin. PY - 2003/7/1. Y1 - 2003/7/1. N2 - Background: Ascorbic acid supplementation has been recommended to circumvent resistance to erythropoietin, which sometimes occurs in iron-overloaded uremic patients. In considering the pro-oxidant effect of ascorbic acid, the authors hypothesize that adjuvant therapy with larger doses of ascorbic acid in hemodialysis patients with iron overload may raise the risk of increasing free radical generation. The oxidative stress of intravenous ascorbic acid supplementation in hemodialysis patients was evaluated in this study. Methods: Six healthy subjects and 29 hemodialysis patients were enrolled. Chemical scavenging activity of various compounds was measured by in vitro ...
article{141703, author = {Langlois, Michel and Duprez, Daniel and Delanghe, Joris and De Buyzere, Marc and Clement, Denis}, issn = {0009-7322}, journal = {CIRCULATION}, language = {eng}, number = {14}, pages = {1863--1868}, title = {Serum vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis (with comment: Vitamin C depletion linked to inflammation in peripheral artery disease. M. Larkin Lancet, 357, 2001, 1184).}, volume = {103}, year = {2001 ...
Mason, Shaun, Rasmussen, Bodil and Wadley, Glenn 2018, Ascorbic acid supplementation improves postprandial glucose and blood pressure in people with Type 2 diabetes, in 78th Scientific Sessions, American Diabetes Association, American Diabetes Association, [Orlando, Florida], doi: 10.2337/db18-789-P. ...
The aim of the present study was to investigate if the depletion of UV-B radiation affected the most representative carotenoids as well as the ascorbic acid content in tomato fruits, harvested at both breaker and firm red stages. To do this, three tomato genotypes, DRW 5981, HP 1, and Esperanza, were grown inside a greenhouse either covered with polyethylene transparent to UV-B or depleted of UV-B by a special covering film. The antioxidant properties of the fruits were evaluated on the water-insoluble fractions according to the ABTS method. UV-B effect on antioxidant activity was negligible in DRW and HP 1 genotypes, whereas it was detrimental in Esperanza at both ripening stages. This genotype seems to have a negligible capability of accumulating carotenoids and a great susceptibility to detrimental effects of UV-B; conversely, the DRW genotype shows high carotenoid levels under sunlight conditions and a further promotion by UV-B. On the other hand, the HP 1 mutant displays an intermediate ...
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Schedule Appointment. Intravenous Vitamin C Therapy with various other antioxidants and nutrients has been used for years as a treatment option for various types of cancer. The very high doses of Intravenous Vitamin C (15 to 100 grams/infusion) appear to be toxic (lethal) to cancer cells. It is used to stabilize membranes, boost the immune system, and increase energy. It also has anti-viral, anti-bacterial and anti-histamine properties. High doses of vitamin C given intravenously have very few side effects. Intravenous Vitamin C Therapy is not a cure for cancer but a viable treatment option.. Components of High Dose Intravenous Vitamin C & Mineral Infusions can include:. ...
Hypothesis 1A: Vitamin C infusion will significantly attenuate sepsis-induced systemic organ failure as measured by Sequential Organ Failure Assessment (SOFA) score,. Hypothesis 1B: Vitamin C infusion will attenuate sepsis-induced lung injury as assessed by the oxygenation index and the VE40. Hypothesis 1C: Vitamin C infusion will attenuate biomarkers of inflammation (C-Reactive Protein, Procalcitonin), vascular injury (Thrombomodulin, Angiopoietin-2), alveolar epithelial injury (Receptor for Advanced Glycation Products), while inducing the onset of a fibrinolytic state (Tissue Factor Pathway Inhibitor). ...
Low maternal dietary vitamin E (but not vitamin C) intake during pregnancy has been associated with increased in vitro cord blood mononuclear cell (CBMC) proliferative responses, childhood wheezing and asthma. We investigated whether these associations reflect direct effects of vitamin E by investigating the effects of supplementing CBMC cultures with physiological concentrations of vitamin E. CBMC from seventy neonates were cultured supplemented with either nothing, α-tocopherol or ascorbic acid. Proliferative, IFN-γ, IL-4, IL-10 and TGF-β responses were measured. In general, vitamin E supplementation was associated with a trend for reduced proliferative responses after stimulation with antigens and house dust mite, and with increased proliferation after stimulation with timothy grass allergen. There was a trend for CBMC cultures to exhibit decreased secretion of IFN-γ, IL-10 and IL-4. Supplementation with vitamin C had no effect on CBMC proliferation, but increased IFN-γ and IL-4 production,
Background In the setting of atherosclerosis, endothelial vasomotor function is abnormal. Increased oxidative stress has been implicated as one potential mechanism for this observation. We therefore hypothesized that an antioxidant, ascorbic acid, would improve endothelium-dependent arterial dilation in patients with coronary artery disease. Methods and Results Brachial artery endothelium-dependent dilation in response to hyperemia was assessed by high-resolution vascular ultrasound before and 2 hours after oral administration of either 2 g ascorbic acid or placebo in a total of 46 patients with documented coronary artery disease. Plasma ascorbic acid concentration increased 2.5-fold 2 hours after treatment (46±8 to 114±11 μmol/L, P=.001). In the prospectively defined group of patients with an abnormal baseline response (,5% dilation), ascorbic acid produced marked improvement in dilation (2.0±0.6% to 9.7±2.0%), whereas placebo had no effect (1.1±1.5% to 1.7±1.5%, P=.003 for ascorbic acid ...
Why was I offered an infusion of vitamin C?. With my compromised immune system, I am susceptible to bacterial infections. As getting the best available treatment urgently has been drummed into me by my medical team, I do my best to avoid any kind of preventable illness. I had not heard of a vitamin C infusion as a first line of treatment, so asked for the evidence. I was told that the practice "uses vitamin C a lot, and has some really excellent results for all kinds of conditions". The GP, too, was also unable to offer a plausible biological explanation. The infusion was to be administered by the practice nurse and was to cost $130.. This is not the only medical practitioner offering vitamin C infusions and other unproven interventions. A growing number of medical clinics, claiming to be holistic, integrative, anti-ageing or health and wellness; centres, are offering a "comprehensive integrated approach to health and delaying aging based upon the biology of the neuroendocrine system, ...
The purposes of the present study are to determine the ascorbic acid values of foods served in the lunch room of North Texas State Teachers College Demonstration School at the time food preparation is completed, at the beginning of the serving period, and at the end of the serving period; to ascertain the loss of ascorbic acid during these intervals; and to determine the quantity of ascorbic acid present in the size portions served primary, elementary, and high school students.
Description: Ascorbyl Palmitate is a fat-soluble form of Vitamin C that can cross the blood-brain barrier and cell membranes. As a form of Vitamin C, it provides antioxidant activity and is intended to provide nutritive support for normal, healthy collagen synthesis, cartilage and bone development, immune function, capillary and blood vessel integrity and nerve impulse transmission. Size: 60ct 500mg Directions: Take 1 capsul daily. Serving Size: 1 Capsule 60 Servings per container Ingredients: Amount Per Serving - % Daily Value Vitamin C (as Ascorbyl Palmitate) 215 mg 358% Other Ingredients: Gelatin Capsule, Cellulose, Silica and Magnesium Stearate
Purpose: : To investigate the effect of ultraviolet radiation-B (UVR-B) exposure on lens ascorbate concentration in the pigmented guinea pig. Methods: : Twenty 20 pigmented guinea pigs were randomly divided into two groups. One group received drinking water supplemented with 0 mM ascorbate while the other group received drinking water supplemented with 5.5 mM ascorbate, for four weeks. All animals were thereafter unilaterally exposed to UVR-B. One day after the exposure to UVR, the animals were sacrificed and the lenses were removed for measurement of intensity of forward light scattering. Ascorbate concentration was measured once in each lens using ultrafiltration and HPLC with UVR detection. Results: : There was no significant difference of ascorbate content between exposed and not exposed lenses in either of the 0 mM or the 5.5 mM group [t-test]. Anterior subcapsular cataract developed in all exposed lenses and none of not UVR-exposed lenses. In both the ascorbate-supplemented and the not ...
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[150 Pages Report] Check for Discount on Global and Chinese Ascorbyl palmitate (CAS 137-66-6) Industry, 2016 Market Research Report report by Prof Research. The Global and Chinese Ascorbyl palmitate Industry, 2011-2021 Market...
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This cancer information summary provides an overview of the use of high-dose vitamin C (also known as ascorbate or L-ascorbic acid) as a treatment for people with cancer. This summary includes a brief history of early clinical trials of high-dose vitamin C; reviews of laboratory, animal, and human studies; and current...
The effect of acute endotoxin-induced septic shock on myocardium oxidative stress after low or high vitamin C and/or E dietary supplementation was studied in guinea pigs, laboratory animals which, like human, do not have capacity for ascorbate synthesis. Neither the antioxidant enzymes or GSH were modified by endotoxin and vitamin treatments. Vitamin E showed a strong capacity to protect the myocardium against both enzymatic and non-enzymatic lipid peroxidation even in the presence of endotoxin. Vitamin C supplementation increased heart ascorbate whereas endotoxic shock totally depleted the heart ascorbate of vitamin C supplemented animals without changing vitamin E. Endotoxin significantly increased myocardium uric acid, a marker of ischemia induced oxidative stress, in animals fed with low vitamin C levels. This increase was totally prevented in vitamin C supplemented, but not in vitamin E supplemented animals. Strongly depressed levels of plasma vitamin C have been recently described in ...
The effect of acute endotoxin-induced septic shock on myocardium oxidative stress after low or high vitamin C and/or E dietary supplementation was studied in guinea pigs, laboratory animals which, like human, do not have capacity for ascorbate synthesis. Neither the antioxidant enzymes or GSH were modified by endotoxin and vitamin treatments. Vitamin E showed a strong capacity to protect the myocardium against both enzymatic and non-enzymatic lipid peroxidation even in the presence of endotoxin. Vitamin C supplementation increased heart ascorbate whereas endotoxic shock totally depleted the heart ascorbate of vitamin C supplemented animals without changing vitamin E. Endotoxin significantly increased myocardium uric acid, a marker of ischemia induced oxidative stress, in animals fed with low vitamin C levels. This increase was totally prevented in vitamin C supplemented, but not in vitamin E supplemented animals. Strongly depressed levels of plasma vitamin C have been recently described in ...
The relatively common condition known as premature rupture of the chorioamniotic membranes (PROM) may result in premature delivery and infection. Earlier studies have found that vitamin C plays an important role in maintaining the collagen in the membrane throughout gestation but it is not stored well by the body, which excretes whatever it does not need on a daily basis.. The researchers, led by Esther Casanueva, set out to determine the effectiveness of a daily 100mg dose in preventing PROM.. In the controlled double-blind trial, 120 women in their 20th week of pregnancy were randomly assigned to two groups; one group received 100mg of vitamin C each day and the other received a placebo.. The womens plasma and leukocyte vitamin C concentrations were measured every fourth week and the results published in the April issue of the American Journal of Clinical Nutrition​ (81, 4: 859-863).. They showed that mean plasma vitamin C concentrations decreased as pregnancy progressed in all of the 109 ...
Fat-soluble vitamin C Ascorbyl palmitate is a highly bioavailable, fat-soluble derivative of ascorbic acid. It possesses all the benefits of vitamin C, but, unlike the water-soluble form, is able to be stored in the lipid cell membrane until the body is ready to put it to use. Vitamin C offers a wide range of support for the human body. It is a potent antioxidant and free radical scavenger. It supports the body by enhancing defense system cell activity. It is essential for the formation and maintenance of intercellular ground substance and collagen. Vitamin C aids in the absorption of iron and the formation of red blood cells and converts folic acid to active folinic acid. It maintains healthy histamine release and supports lymphocyte formation. Vitamin C is also required for the synthesis of carnitine and steroids. Vitamin C, one of the most potent dietary antioxidants, provides optimal nutritional support to all physiological functions, including, notably, vascular and capillary integrity in
Find patient medical information for VITAMIN C ASCORBIC ACID on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and products that have it.
AIMS Vitamin C (ascorbic acid) is thought to enhance immune function, but the mechanisms involved are obscure. We utilized an in vitro model of T-cell maturation to evaluate the role of ascorbic acid in lymphocyte development. RESULTS Ascorbic acid was essential for the developmental progression of mouse bone marrow-derived progenitor cells to functional T-lymphocytes in vitro and also played a role in vivo. Ascorbate-mediated enhancement of T-cell development was lymphoid cell-intrinsic and independent of T-cell receptor (TCR) rearrangement. Analysis of TCR rearrangements demonstrated that ascorbic acid enhanced the selection of functional TCRαβ after the stage of β-selection. Genes encoding the coreceptor CD8 as well as the kinase ZAP70 were upregulated by ascorbic acid. Pharmacologic inhibition of methylation marks on DNA and histones enhanced ascorbate-mediated differentiation, suggesting an epigenetic mechanism of Cd8 gene regulation via active demethylation by ascorbate-dependent Fe(2+) and 2
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Ascorbate and glutathione (GSH) are the primary water-soluble antioxidants in the CNS. Oxidative stress, sometimes indicated by loss of these antioxidants, has been linked to several clinical and experimental conditions, including cerebral ischemia. These conditions are also gender-linked, with greater incidence or severity in males than females. To test whether there are gender differences in oxidant/antioxidant regulation, we determined basal levels of ascorbate and GSH in rat brain and their loss after 1 h decapitation ischemia. We found that ascorbate levels in male rat brain were 7-10% higher than in females, depending on region, whereas GSH levels were gender-independent. Significant ascorbate loss (up to 12%) occurred in males during ischemia, with a regional pattern of cerebellum | hippocampus | prefrontal cortex. Loss of ascorbate in females was not significant in any region. By contrast, loss of GSH was significant in both males and females. Greater loss of GSH than ascorbate was in agreement
Per 100 g, the leaf is reported to contain 73.1 g H2O, 8.4 g protein, 1.4 g fat, 11.8 g NFE, 2.2 g fiber, 3.1 g ash, 1,130 mg Ca, 80 mg P, 3.9 mg Fe, 9,000 IU vit. A, 0.21 mg thiamine, 0.09 mg riboflavin, 1.2 mg niacin, and 169 mg ascorbic acid. Leaves contain (ZMB) per 100 g, 321 calories, 36.3 g protein, 7.5 g fat, 47.1 g carbohydrate, 9.2 g fiber, 9.2 g ash, 1684 mg Ca, 258 mg P, 21 mg Na, 2,005 mg K, 25,679 mg b-carotene equivalent, 1.00 mg thiamine, 1.04 mg riboflavin, 9.17 mg niacin and 242 mg ascorbic acid. The flowers (ZMB) contain per 100 g, 345 calories, 14.5 g protein, 3.6 g fat, 77.3 g carbohydrate, 10.9 g fiber, 4.5 g ash, 145 mg Ca, 290 mg P, 5.4 mg Fe, 291 mg Na, 1,400 mg K, 636 mg b-carotene equivalent, 0.91 mg thiamine, 0.72 mg riboflavin, 14.54 mg niacin, and 473 mg ascorbic acid. Seeds (ZMB) contain 36.5% CP, 7.4% fat, 51.6% total carbohydrate, and 4.5% ash. The seed oil contains 12.3% palmitic, 5.2% stearic, 26.2% oleic, and 53.4% linoleic acids. The seed testa, which ...
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Supplemental vitamin C taken by pregnant smokers improved measures of lung function for newborns and decreased the incidence of wheezing for infants through one year, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the American Thoracic Society International Conference.
Low levels of vitamin C were associated with higher levels of high sensitivity C-Reactive protein (hsCRP) and shorter intervals without major cardiac issues or death for heart failure patients, in research presented at the American Heart Associations Scientific Sessions 2011.. Compared to those with high vitamin C intake from food, heart failure patients in the study who had low vitamin C intake were 2.4 times more likely to have higher levels of hsCRP, a marker for inflammation and a risk factor for heart disease.. The study is the first to demonstrate that low vitamin C intake is associated with worse outcomes for heart failure patients.. Study participants with low vitamin C intake and hsCRP over 3 milligrams per liter (mg/L) were also nearly twice as likely to die from cardiovascular disease within one year of follow-up.. "We found that adequate intake of vitamin C was associated with longer survival in patients with heart failure," said Eun Kyeung Song, Ph.D., R.N., lead author of the ...
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Vitamin C is a nutrient found in food and dietary supplements. It is an antioxidant and also plays a key role in making collagen (see Question 1). High-dose vitamin C may be given by intravenous (IV) infusion (through a vein into the bloodstream) or orally (taken by mouth). When taken by intravenous infusion, vitamin C...
I started a stain treatment yesterday with 2lbs of ascorbic acid, 1 qt of algecide and 1 qt of Jacks Pink Stuff. However, the FC was at 2.5 (I was impatient) and I still have stains even though I think they are lighter. Now, its 8:15 pm and raining. However, my FC is 0, PH is 7.2, ALK is 70. I have 1lb of ascorbic acid and 2 qts of the Pink Stuff left. Should I try now? It seems my numbers are perfect but Im not sure if the rain will make a difference. Or should I just go put a jug of bleach
What is high-dose vitamin C? Vitamin C (also called L-ascorbic acid or ascorbate) is a nutrient that humans must get from food or dietary supplements since it cannot be made in the body. Vitamin C is an antioxidant and helps prevent oxidative stress. It also works with enzymes to play a key role in making collagen.. When taken by intravenous (IV) infusion, vitamin C can reach much higher levels in the blood than when it is taken by mouth. Studies suggest that these higher levels of vitamin C may cause the death of cancer cells in the laboratory.. A severe deficiency (lack) of vitamin C in the diet causes scurvy, a disease with symptoms of extreme weakness, lethargy, easy bruising, and bleeding. The lack of vitamin C in patients with scurvy makes collagen thinner in texture; when vitamin C is given, collagen becomes thicker again.. ...
Low prices on Vitamin C! Vitamin C is a powerful antioxidant that benefits the whole body*. Vitamin C supports the immune system and the formation of healthy connective tissue throughout the body.* It cannot be made or stored by the body, so supplementing with vitamin C is essential.V itamin C is available in a variety of potencies and forms, such as capsules, tablets, time-released formulas, effervescent drink mixes, chewables and powders.
Vitamin C is thought to be an important local protective factor against gastric carcinogenesis. H pylori infection induces marked infiltration of inflammatory cells within the gastric mucosa; these inflammatory cells such as neutrophils and monocytes synthesise and release copious amounts of toxic ROMs26 which may be neutralised by vitamin C and other antioxidants in the stomach. Gastric epithelial cells actively secrete ascorbic acid, the reduced form of vitamin C, into gastric lumen, where there is a significantly higher concentration than that in plasma in healthy subjects.27,28 There is variation in gastric juice concentrations of vitamin C (ascorbic acid alone or plus DHA) in healthy subjects according to the methods and subjects involved in the studies. Although low levels have been reported,29 most studies in the fasting stomach have detected ascorbic acid concentrations in the range 50 to 400 μM. However, gastric juice vitamin C is significantly reduced or even absent in H pylori ...
Vitamin C is water-soluble, and probably the most famous of all the vitamins. Even before its discovery in 1932, physicians recognised that there must be a compound in citrus fruits preventing scurvy, a disease that killed as many as 2 million sailors between 1500 and 1800. Later researchers discovered that man, other primates and the guinea pig depend on external sources to cover their Vitamin C requirements. Most other animals are able to synthesise Vitamin C from glucose and galactose in their body. The most prominent role of Vitamin C is its immune stimulating effect, which is important for the defence against infections such as common colds. It also acts as an inhibitor of histamine, a compound that is released during allergic reactions. As a powerful antioxidant it can neutralise harmful free radicals and aids in neutralising pollutants and toxins. Thus it is able to prevent the formation of potentially carcinogenic nitrosamines in the stomach (due to consumption of nitrite-containing ...
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People who have used high doses of traditional vitamin C often experience a watery diarrhea, called a C-flush. This phenomenon happens whenever a large amount of vitamin C is not absorbed in the small intestine. The unabsorbed vitamin C reaches the colon where it draws water into the bowels. At the point of bowel tolerance, a watery diarrhea naturally ensues. This is not an adverse side effect, it simply happens because the intestines cannot handle the volume of water the vitamin C draws into the large bowel. The vitamin C dosage that initiates a C-flush is referred to as a "bowel tolerance" dosage.. Daily bowel tolerance dosing to determine your current need for vitamin C can be inconvenient and unpleasant, but a good strategy includes periodic utilization of this type of vitamin C supplementation. Once a month, or even once a week, take spaced doses of vitamin C powder dissolved in water until the onset of diarrhea. At this point a baseline dose can be determined, and the bowels will benefit ...
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The need for additional Vitamin C (Ascorbic Acid) is increased during periods of emotional, psychological or physiological stress. During this time urinary excretion of Vitamin C is increased. The functions of Vitamin C in the human body are very diverse. It participates in the synthesis of collagen by hydroxylating proline to form hydroxyproline, the major protein from which connective tissue, cartilage, bone, skin, tendon and tooth dentin is made. It desaturates fatty acids, acts as an antioxidant, increases absorption of nonheme iron and oxidates Phenylalanine and Tyrosine. Vitamin C also promotes resistance to infections by boosting the immune system. We use only USP quality (99.5% or higher purity) Vitamin C. We provide a teaspoon scoop (1 gram dose) for your convenience. pH = 2.3.* Supplement facts: Serving size teaspoon (1000 mg) Servings per container 454 Amount per serving: Vitamin C (as Ascorbic Acid) 1000 mg Suggested Use: 1/4 teaspoon (1000 mg) daily as a dietary supplement, or
Biologics have changed the management of inflammatory bowel disease (IBD), but there are concerns with unexpected systemic toxicity and loss of therapeutic response following administration by injection. Rectal administration of biologics offers potentially reduced therapy costs, as well as safer and more effective local delivery to inflammation sites. Hydrogels are potentially useful carriers of biologics for improved delivery to the inflamed intestinal mucosa. Here, we prepared a hydrogel system based on ascorbyl palmitate (AP) and incorporated a model macromolecular drug (fluorescently-labelled dextran) into the system. Characterization of gel properties included rheology, drug loading and release, cytotoxicity, and drug delivery in an in vitro intestinal model. We report that this hydrogel can be formed under a moderate environment that is amenable to incorporation of some biologics. The system showed a shear-thinning behavior. AP hydrogel released approximately 60% of the drug within 5 h and showed
Charcot Marie Tooth disease (CMT), or inherited peripheral neuropathies, are among the most frequent heritable disorders, affecting approximately 1 in 2500 people. The most frequent genetic form of CMT is CMT1A. CMT1A is caused by a 1.4 Mb duplication within chromosome 17p11.2 in the region containing the PMP22 gene. Most subjects with CMT1A have a typical phenotype characterized by onset in childhood or early adulthood, distal weakness, sensory loss, foot deformities and absent reflexes. How increased expression of PMP22 causes these disabilities is unknown but is currently being investigated in both animal and tissue culture systems. In this study, researchers will evaluate whether ascorbic acid (Vitamin C), administered orally, slows clinical progression of CMT1A and affects the PMP22 mRNA levels of myelinated peripheral nerve fibers obtained from biopsies of glabrous skin ...
http://profiles.nlm.nih.gov/MM/B/B/R/R/_/mmbbrr.pdf ]. To the Editor: An article in your Sept. 30 Week in Review section, "Vitamin C Fails as a Cancer Cure" (with reference to me in the first sentence), said that a controlled study of 150 Mayo Clinic patients with advanced cancer, published in the New England Journal of Medicine, had shown no evidence that large doses of vitamin C help.. This is indeed what was reported by the Mayo Clinic investigators. They themselves and The Times article do not point out, however, that the population of cancer patients investigated in the Mayo Clinic was so different from that investigated by my associate Dr. Ewan Cameron in Vale of Leven Hospital, Loch Lomondside, Scotland, that the results observed in the Mayo Clinic study cannot be considered to refute the results observed in the study in Scotland.. The chief investigator in the Mayo Clinic study wrote to me last year that he hoped to repeat Dr. Camerons work as closely as possible. I then wrote to him, ...
High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men Journal Article ...
Acccording to the study of "Vitamin C and acute respiratory infections" by Hemilä H, Douglas RM., posted in US National Library of Medicine National Institutes of Health, researchers wrote that one randomised trial reported substantial treatment benefit from vitamin C in elderly UK patients hospitalized with pneumonia or bronchitis. It seems that the preventive effects of supplementation are mainly limited to subjects with low dietary vitamin C intake, but therapeutic effects may occur in wider population groups. Further carefully designed trials are needed to explore the effects of vitamin C ...
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I did the ascorbic acid treatment about a month ago. While the chlorine was at zero, I had Polyquat-60 in. The chlorine was brought back up slowly, as the directions for the ascorbic acid treatment indicated. That was finished 2-3 weeks ago. Based on what Ive read here, Im pretty sure that the ascorbic acid and Polyquat-60 effects on the chlorine are long past. The problem is that I cant get the chlorine to hold. For the past 2 weeks Ive been losing 4-5 ppm per day, as opposed to the 1-2
If this post has helped you, please would you help me? I am now fundraising for cancer treatments at GoFundMe http://www.gofundme.com/78jh2w or at JustGiving: https://www.justgiving.com/goBananasforRona Revised 7 April 2014 re. importance of oxygen supply to tumour Ive posted previously about IV C. Despite adhering to a strict regime of 3 x 6 days a week of infusions plus twice weekly…
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
2/1/17(Natural News) It would be naive to think that the FDA endeavors to protect the publics health as its primary focus. Indeed, that would be a conflict of interest, as it serves its master,...read more
IV therapy uses high dose vitamins, minerals and natural substances intravenously or intramuscularly to treat many health concerns and diseases. It is primarily used for chronic or debilitating conditions that require additional support in the healing process and it is used as part of cancer treatments. Contact us for answers to frequently asked questions about intravenous therapy and its role in the healing process.. Some of the conditions that IV therapy benefits:. ...
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Intravenous Vitamin (IV) Therapy is helpful for a variety of conditions, often producing dramatic results. By administering nutrients intravenously, concentrations not obtainable by oral administration can be achieved, effectively flooding the bodys ce
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Results Of the 62 patients screened, 24 met the study inclusion criteria. Of these, 13 were assigned to receive ascorbic acid and 11 received placebo. Ascorbic acid did not affect the natural course of inflammatory marker rise for C-reactive protein (CRP) concentration, white blood cell (WBC) count, or fibrinogen concentration versus placebo at any evaluated time point (p , 0.05 for all intergroup comparisons). Intragroup analyses demonstrated significant differences among baseline and postoperative measures of all inflammatory mediators (p , 0.05). No significant differences were noted in inflammatory markers between patients undergoing cardiothoracic surgery with or without cardiopulmonary bypass, regardless of treatment group. ...
Increase your Vitamin C. Studies indicate that as little as 250 mg of this antioxidant daily after surgery can reduce recovery time in half. Vitamin C offers support to the immune system and promotes healing. In most instances it is possible to significantly boost Vitamin C with no adverse reactions with surgery. For patients facing invasive procedures and people with compromised immune systems, a nutritional IV with high doses of Vitamin C can be the easiest and most effective way to support the body. Vitamin C supplementation and IV therapy can be started prior to and continue after surgery for most people. To boost Vitamin C levels prior to surgery, take between five and ten grams daily in divided doses the week leading up to surgery. Too much Vitamin C will result in a looser-than-normal stool and indicates that someone should back off on the dose but not stop taking it ...
The aim of this study was to i nvestigate whether post-exercise vitami n C suppleme ntatio n i nflue nces recovery from a n u naccustomed bout of exercise. Sixtee n male subjects were allocated to eit
The blood vessels of overweight and obese adults have elevated activity of the small vessel-constricting protein endothelin (ET)-1. Because of the high ET-1 activity, these vessels are more prone to constricting, becoming less responsive to blood flow demand and increasing risk of developing vascular disease. Exercise has been shown to reduce ET-1 activity, but incorporating an exercise regimen into a daily routine can be challenging. This study, conducted at the University of Colorado, Boulder, examined whether vitamin C supplements, which have been reported to improve vessel function, can also lower ET-1 activity. The researchers found that daily supplementation of vitamin C (500 mg/day, time-released) reduced ET-1-related vessel constriction as much as walking for exercise did. Vitamin C supplementation represents an effective lifestyle strategy for reducing ET-1-mediated vessel constriction in overweight and obese adults, the researchers wrote ...
Hydraplenish plus Vitamin C Serum information including description from Natures Way, supplement facts, and suggested use. Order online for quick delivery at the best prices.
Natural News) In order to have stronger, healthier bones, all you need to do is to drink orange juice daily. According to a report by The Daily Mail, a new study suggests that increasing your intake of vitamin C can reduce the risk of hip fractures.. Researchers from Zhengzhou University in China carried out a meta-analysis to assess the association of dietary consumption of vitamin C and the risk of hip fracture. In the study, they analyzed data from a total of six previous studies on vitamin C and fracture risk, with more than 10,000 study participants in all. For this study, they observed the vitamin C intake of 2,899 patients with hip fracture. Then, they compared the results with 7,908 healthy volunteers of a similar age. The meta-analysis on vitamin C and its effect on bones revealed that vitamin C consumption, whether by eating foods rich in vitamin C or drinking their juice, make bones stronger and prevents fractures.. The findings of the study revealed that the risk of a hip fracture ...
Our highest strength of vitamin C with 1000mg in a sustained-release tablet to help maximize tissue retention and reduce excess loss typical of regular forms.
In studies at two area health care centers, 30% of new admissions with a diagnosis of depression had low plasma vitamin C levels. Actually, we did this study a number of years ago and found that if you took a hundred people who are depressed without checking their level and gave them all vitamin C, 30% would get better. Statistically that would be below the placebo level. That is why it is important to separate out the 30% from the large group, so the people who are low in vitamin C will obviously respond more to the vitamin C than the people who are not. Of course, man and woman does not live by vitamin C alone. It is possible to become depressed because of the lack of a sufficient amount of a single trace element. The following is from an audio tape of a person who had this problem: "I was getting more depressed. I had two grand babies coming at the end of July and I didnt want to see them. Thats rather odd for a grandmother. I knew I wasnt up to helping my children with their children. I ...
WHY VITAMIN C SERUM? Taking vitamin C through a supplement or food is beneficial to your health, but to specifically target signs of aging on your face, topical vitamin C is best. Applying Vitamin C to the skin is up to 20 times more effective than taking it orally - Dr. Oz. One of the most powerful functions of vitamin C is its role in the production of collagen, a protein that gives your skin its elasticity. As you age, collagen breaks down and wrinkles begin to form. Stabilizing your skins levels of vitamin C can help to counteract wrinkle formation by increasing collagen production. Vitamin C helps boost collagen, which will bring elasticity to your skin and can prevent sagging in as little as 2 weeks - Dr. Oz When it comes to treating age spots, you dont need chemical peels and lasers - Vitamin C can have almost the same results! Age spots are essentially sun damage, and Vitamin C is a powerful antioxidant, shown to reduce the number of sunburned cells as well as reverse age-related ...
Plasma vitamin C was lower in periodontitis patients compared with controls (8.3 and 11.3 mg/l, respectively, p = 0.03). Only in the control group a positive correlation was present between vitamin C intake and plasma values. No differences could be assessed between patients and controls regarding vitamin C dietary intake and levels in PMNs and PBMCs. In the patient group, pocket depth appeared to be negatively associated with the vitamin C concentration in PMNs ...
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Laboratory, animal and clinical research has revealed that vitamin C ameliorates radiation damage at a cellular level. Specifically, vitamin C causes significant and immediate reductions in DNA damage, which often sets the stage for cancer. An animal study showed that pretreatment with vitamin C increased sperm head survival after the injection of radioactive iodine-131 in mice, while another study showed that the vitamin markedly improved intestinal damage following massive irradiation.. In addition, a clinical study showed that a combination of alpha-lipoic acid and vitamin E decreased urinary radioactivity and oxidative stress in children who had suffered from radiation exposure at Chernobyl. And, finally, a study of 17 workers who had undergone severe radiation exposure at the Fukushima nuclear plant revealed that supplementation with vitamin C and other antioxidants reduced their cancer risk. Workers who took intravenous vitamin C before they entered the plant - and consistently took ...
Agreement among three indicators of vitamin C status-serum ascorbate level, a 24-hour recall, and the frequency of fruit and vegetable consumption-was examined using data from the Second National Health and Nutrition Examination Survey conducted between 1976 and 1980. Agreement between pairs of these indicators was good when assessed at the...
An experiment was conducted to evaluate the efficacy of intra-amnion administration of different doses of ascorbic acid (AA) on hatchability, growth performance, blood metabolites, jejunal morphology, and tibia breaking strength in 36h post hatch fasted broiler chickens. Two hundred eighty-eight Ross-308 fertile eggs at the 15thday of incubation were divided into four treatment groups, each containing four replicates of 18 eggs. The treatments included non-injected (control), injected into the amnion with 0.7 mL diluent (distilled water; sham treatment), and injected with 0.7 mL diluent containing 3 or 6 mg AA. The neonatal chicks were deprived of feed and water for 36 h. Hatched chicks were raised till 10 d of age. Hatch percentage was increased due to in ovo injection of 6 mg/egg AA.In ovo injection of different levels of AA had no significant effect on body weight gain, feed intake, and feed conversion ratio. In ovo injection of AA, especially at the 6 mg level, significantly increased villus height,
This example compares two binomial proportions by using a log odds ratio statistic in a five-stage group sequential test. A clinic is studying the effect of vitamin C supplements in treating flu symptoms. The study consists of patients in the clinic who exhibit the first sign of flu symptoms within the last 24 hours. These patients are randomly assigned to either the control group (which receives placebo pills) or the treatment group (which receives large doses of vitamin C supplements). At the end of a five-day period, the flu symptoms of each patient are recorded. Suppose that you know from past experience that flu symptoms disappear in five days for 60% of patients who experience flu symptoms. The clinic would like to detect a 70% symptom disappearance with a high probability. A test that compares the proportions directly specifies the null hypothesis ...
This example demonstrates group sequential tests that use an OBrien-Fleming group sequential design. A clinic is studying the effect of vitamin C supplements in treating flu symptoms. The study consists of patients in the clinic who have exhibited the first sign of flu symptoms within the last 24 hours. These patients are randomly assigned to either the control group (which receives placebo pills) or the treatment group (which receives large doses of vitamin C supplements). At the end of a five-day period, the flu symptoms of each patient are recorded. Suppose that you know from past experience that flu symptoms disappear in five days for 60% of patients who experience flu symptoms. The clinic would like to detect a 75% symptom disappearance with a high probability. A test that compares the proportions directly specifies the null hypothesis ...
SkinCeuticals Topical Vitamin-C products contain stable L-ascorbic acid at a low pH, which allows vitamin-C to be absorbed by the skin. Most commonly marketed products utilise vitamin-C derivatives such as ascorbyl palmitate and magnesium ascorbyl phosphate, which must be converted to L-ascorbic acid in order to be used by the skin.. To be effective, vitamin-C derivatives must first get into the skin and then must be chemically converted by the skins cells into L-ascorbic acid. Because the skin is difficult to penetrate and the enzymes necessary to convert these derivatives into L-ascorbic acid are not always available, derivatives are not very effective in delivering vitamin-C into the skin.. It is the Duke University patented technology and the stability technique developed by Dr. Sheldon R. Pinnell and his colleagues which renders the SkinCeuticals Topical Vitamin-C products effective. In addition, SkinCeuticals Topical Vitamin-C products are designed to reduce the temporary stinging ...
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Exercise is still recommended for those who are overweight, but the study suggests a vitamin C supplement can help those patients who cant or wont pursue activity.
I am so glad to have found this page as I had my NT ultrasound 2 days ago with a reading of 6. If the tests lead your physician recommended vitamin c intake during pregnancy suspect that prostate cancer may be indicated, a biopsy will likely be performed. Make certain your consumption of calcium and magnesium is satisfactory by eating plenty recommended vitamin c intake during pregnancy leafy inexperienced greens and cheese. Adam Urato, a maternal-fetal medication specialist at Tufts Medical Middle in Boston, says that as a society, we have turn out to be too cavalier - too relaxed - about the situation of chemical exposures in pregnancy. Many women also have large families in order to HOLD ON oregnancy their husbands and THEY LOVE the attention that being pregnant entails. 30,2012 Nd Ended Jan. According to one study in the journal Fertility and Sterility, 17 percent of women who had conceived through IVF how many stripes on a pregnancy test got pregnant naturally shortly after. Neither of us ...
Indications: skin diseases, hair and nails, anemia, gynecological and ocular osłabiebie, the collapse of the immune system, symptoms and diseases of old age, diabetes, obesity, cardiovascular disease, cancer, treatment with salicylates, infectious disease, hemorrhagic, hormonal disorders,convalescence, spots on the skin, teeth decay.
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High-Quality Liposomal Vitamin C Contains 1000mg of Liposomal Vitamin C, 175mg of Quercetin plus 1000mg PC per serving. Liposomal Vitamin C is gluten-free, non-GMO and non-soy. No better way to orally supplement Vitamin C - guaranteed! Protects Healthy Cells Compared with tablet or powdered vitamin C, Liposomal vitamin C goes straight to the source, using its expedited delivery system to reach cells up to 10 hours faster than over-the-counter tablets. No Side Effects Liposomal Vitamin C rapidly raises blood concentrations without any side effects that are often associated with high doses of Vitamin C. Various Benefits For Optimal Health Vitamin C has countless health benefits, with the potential to support immune function, brain health, blood sugar and heart health. Vitamin C may help to maintain healthy bones, cartilage and connective tissues. Its needed by the body to protect against stress and injury. By combining CureC™ with Quercetin, it enhances antioxidant enzymes produced in the body and
Find the best vitamin C supplement and learn about the health benefits of vitamin C, whether it can help for colds, different forms (ascorbic acid, sodium ascorbate, calcium ascorbate, liposomal vitamin C), dosage, safety, potential side effects and more.
Graphic by Nate Barton Ever heard someone say that drinking orange juice or taking a vitamin C supplement helps combat a cold? Nearly everyone has, but studies show that that vitamin C has little effect on colds. With the number of students who catch colds during the year, it would be nice if there was a surefire way to prevent illness, but the answer is not vitamin C.. According to the Linus Pauling Institue Micronutrient Infromation Center, the claim that vitamin C could be a possible treatment for respiratory infections began gaining popularity in 1970 when, after several tests, Linus Pauling concluded that the vitamin might relieve and prevent colds. Since then, many studies have been conducted on the matter and the results are not inspiring.. A group of studies conducted by Harri Hemila and Elizabeth Chalker in 2013 for the Cochrane Acute Respiratory Infections Group tested the effect of vitamin C in preventing and treating colds. Their results showed that vitamin C, when taken daily before ...
Vitamin C, known as L-ascorbic acid in medical terms, is a water resolvable vitamin that is biologically appears in certain food items. Even Vitamin C is accessible as a dietary add-on. The human being is incapable to produce vitamin C endogenously, thus it is a crucial dietary constituent. Water-soluble vitamins melt in water an excess quantity of the vitamin exit from the body via urine. So we need a nonstop source of such vitamins in your nutritional regime. Appearance of ascorbic acid is white to faintly yellowish crystalline fine particles, almost fragrance-free, with a convincing acidic taste.. Functions of Vitamin C:. The most noticeable responsibility of vitamin C is its immunity accelerating power, for instance, it is very vital to fight against illnesses like flu. It also works as an obstruction of histamine, a composite that is discharged through sensitive responses. As a strong antioxidant, vitamin c can counteract damaging free radicals and it supports in defusing toxins and ...
Get radiant results when you use The Ordinary Ascorbyl Glucoside Solution 12%, a topical vitamin C treatment that brightens dull skin tones. For those looking for a visibly brighter complexion, the Ascorbyl Glucoside Solution 12% is a light ser
Get radiant results when you use The Ordinary Ascorbyl Glucoside Solution 12%, a topical vitamin C treatment that brightens dull skin tones. For those looking for a visibly brighter complexion, the Ascorbyl Glucoside Solution 12% is a light ser
Coldrex MaxGrip Lemon + Vitamin C information about active ingredients, pharmaceutical forms and doses by GlaxoSmithKline, Coldrex MaxGrip Lemon + Vitamin C indications, usages and related health products lists
Emergen C Tropical Flavor 36 pkts by Alacer is widely used by athletes and people in all walks of life to provide nutritional support for a great variety of needs, such as starting the day, jogging, weight lifting, general stress, even to help ward off the late afternoon let-down! Emergen-C fizzes in water to furnish 1,000 mg Vitamin C with 28 different mineral electrolytes plus B Vitamins. A delicious invigorating drink with eight times as much potassium as Gatorade. Sweetened with Fructose (except Lite and Lo-Cal) for Quick Energy with Staying Power!Unlike other Vitamin C supplements, its a combination of ascorbic acid (Vitamin C) and specific minerals which make it easier for your body to assimilate and absorb. A great emergency remedy for everything from hangovers to jet lag, its effects last for up to eight hours. Better than a dozen cups of coffee, and healthier. Ingredients: 1000 mg Vitamin C 24 Nutrients 7 B Vitamins Electrolytes Antioxidants Tropical Flavored Fizzy Drink Mix Amount
1. Pelletier, O. & Keith, M.O. Bioavailability of synthetic and natural ascorbic acid. Journal of the American Dietetic Association. 1974; 64: 271-275. 2. Mangels, A.R. et al. The bioavailability to humans of ascorbic acid from oranges, orange juice, and cooked broccoli is similar to that of synthetic ascorbic acid. Journal of Nutrition. 1993; volume 123: pages 1054-1061. (PubMed). 3. Gregory, J.F. Ascorbic acid bioavailability in foods and supplements. Nutrition Reviews. 1993; volume 51: pages 301-309. (PubMed). 4. Yung, S. et al. Ascorbic acid absorption in humans: a comparison among several dosage forms. Journal of Pharmaceutical Sciences. 1982; volume 71: pages 282-285. (PubMed). 5. Nyyssonen, K. et al. Effect of supplementation of smoking men with plain or slow release ascorbic acid on lipoprotein oxidation. European Journal of Clinical Nutrition. 1997; volume 51: pages 154-163. (PubMed). 6. Viscovich M, Lykkesfeldt J, Poulsen HE. Vitamin C pharmacokinetics of plain and slow release ...
Natures True Health recently announced it will be selling its latest product the Liposomal Vitamin C on both Amazon and its web store. This is to allow more people access to this latest breakthrough technology that can help them live naturally healthier lives.. Vitamin C plays a very important role in the body as an anti-histamine. It reduces inflammatory conditions associated with allergies, colds, flu, and fever. Studies have also shown that getting the right dosage of Vitamin C can help improve lung function, reduce infections and many forms of oxidative stress that affect the blood vessels. As a result, it is necessary that the body gets the right amount of Vitamin C in order to stay fit and functional.. Conventional Vitamin C are water soluble vitamins and they do not efficiently interact with the bodys cell membrane wall which is made up of fatty acids. This simply is because water and fats or oil do not mix efficiently. It is estimated that only about 20% of the oral intake Vitamin C is ...
Taking large doses of vitamin C may moderately reduce blood pressure, according to an analysis of years of research by Johns Hopkins scientists.
Vitamin C, also known as L-Ascorbic Acid or L-Ascorbate, is essential vitamin for humans and certain animal species. Acting as an antioxidant, it protects the body against oxidation, assists in several enzymatic reactions including collagen synthesis which can cause extreme symptoms of scurvy when dysfunctional. For animals, these reactions are essential for the healing of wounds and capillary bleeding prevention. Many mammals and plants produce this vitamin themselves, but humans do not nor do they store it which makes vitamin C rich foods important to include in your daily diet. This water soluble vitamin, all species need vitamin C as part of their diet for normal development and growth. Deficiency in this vitamin causes scurvy in humans, a condition known since ancient times, yet not isolated until 1932 and finally synthesized in 1934. Daily dose recommendations of vitamin C are debated and range from 45 Mg-95 Mg per day. Although there are studies suggesting that vitamin C prevents the ...
Some cereals and other foods and beverages are fortified with vitamin C. Fortified means a vitamin or mineral has been added to the food. Check the product labels to see how much vitamin C is in the product.. Cooking vitamin C-rich foods or storing them for a long period of time can reduce the vitamin C content. Microwaving and steaming vitamin C-rich foods may reduce cooking losses. The best food sources of vitamin C are uncooked or raw fruits and vegetables. Exposure to light can also reduce vitamin C content. Choose orange juice that is sold in a carton instead of a clear bottle. ...
Vitamin C is known to protect mucosal tissues from oxidative stress and inhibit nitrosamine formation in the stomach. High consumption of fruits, particularly citrus, and higher circulating vitamin C concentrations may be inversely associated with gastric cancer (GC) risk. We investigated 20 polymorphisms in vitamin C transporter genes SCL23A1 and SCL23A2 and GC risk in 365 cases and 1,284 controls nested within the European Prospective Investigation into Cancer and Nutrition cohort. We also evaluated the association between these polymorphisms and baseline plasma vitamin C levels in a subset of participants. Four SNPs were predictors of plasma vitamin C levels (SLC23A1 rs11950646 and rs33972313; SLC23A2 rs6053005 and rs6133175) in multivariable linear regression models. One SNP (SLC23A2 rs6116569) was associated with GC risk, in particular non-cardia GC (OR = 1.63, 95 % CI = 1.11-2.39, based on 178 non-cardia cases), but this association was attenuated when plasma vitamin C was included in the ...
Abstract: : Purpose: To determine:1. The presence of sodium-dependent vitamin C transporter 1 (SVCT1) and 2 (SVCT2) in mammalian lens and 2. The effects of glucose, H2O2 and agonists for PKA and PKC on ascorbic acid (ASA) transport in lens. Methods: RT-PCR and immunostaining were performed to identify lens SVCT1 and SVCT2. Regulation of ascorbic acid transporters was studied under hyperglycemic conditions. Glucose or ascorbic acid uptake by intact guinea pig and rabbit lenses was determined by incubation in 3H labeled 2-deoxyglucose, and/or 14C labeled ascorbic acid. PKA was activated using membrane permeant cAMP and PKC using PMA. Results: RT-PCR of lens total RNA and immunostaining of lens sections showed the presence of SVCT1 and SVCT2 in mouse and rabbit lens epithelium and fiber cells; however, expression of SVCT2 was higher than that of SVCT1. SVCT 1 and SVCT2 were localized more to the apical side of the lens epithelium. In fiber cells, the SVCTs showed uniform distribution. In lenses ...
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Vitamin C is one of the most important nutrients that the human body needs. Here we tell you all you need know about Vitamin C deficiency and why you should prevent it.
If PKD patients experience these symptoms, such as pale look, bleeding gums, poor appetite and fatigue, it may indicate they are suffering from vitamin C deficiency. Read on and you can find causes and solutions of these symptoms. Cause of
List of Contributors. How to Use This Book.. Part 1 Acidulants.. Acetic acid.. Adipic acid.. Caprylic acid.. Citric acid.. Dehydroacetic acid.. Fumaric acid.. Glucono-delta-lactone.. Lactic acid.. Malic acid.. Phosphoric acid.. Propionic acid.. Sodium diacetate.. Succinic acid.. Tartaric acid.. Part 2 Antioxidants.. Ascorbic acid and isomers (L-ascorbic acid and erythorbic acid).. Ascorbyl palmitate.. Beta-carotene.. Butylated hydroxyanisole (BHA).. Butylated hydroxytoluene (BHT).. Tert-Butylhydroquinone (TBHQ).. Calcium ascorbate.. Citric acid and its salts.. Ethoxyquin.. Ethylenediaminetetraacetic acid (EDTA).. Propyl gallate (PG).. Rosemary extract; natural spice extract.. Sodium ascorbate.. L-Tartaric acid.. Tea extract.. Tocopherols, mixed a (DL), g and d (synthetic).. Tocopherol, mixed natural concentrate.. Part 3 Colourings.. Alkanet.. Allura Red AC.. Aluminium.. Amaranth.. Ammonia caramel.. Annatto.. Anthocyanin.. Beetroot Red.. Beta-apo-80-carotenal (C30).. Black iron oxide.. Brilliant ...
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Author : Sankar Kumar Dey, Durga Pada Dolai, Debasis Mandal, Balaram Das, Sandeep Kumar Dash, Debnarayan Roy and Somenath Roy. Nicotine, a major toxic component of cigarette smoke has been identified as a major risk factor for different diseases. In the present study, we evaluated the protective effects of aqueous extract of Andrographis paniculata (AE-AP) and Vitamin C on lipid peroxidation and antioxidants status against nicotine treated liver and kidney toxicity. A group of male Wistar rats were induced by subcutaneous injection of vehicle, nicotine (2mg/kg body weight/day), nicotine plus AE-AP250 (250 mg/kg body weight/day), nicotine plus AE-AP500 (500 mg/kg body weight/day) and nicotine plus Vitamin C (5 mg/kg body weight/day) for the period of 15 days. Measurement of biochemical marker enzyme lactate dehydrogenase (LDH), lipid peroxidation (MDA), conjugated dienes and antioxidants were used to monitor the antiperoxidative effects of AE-AP and Vitamin C. The decreased biochemical marker ...
Water (Aqua); Zinc Oxide; Cyclopentasiloxane; Butylene Glycol; Glycerin; Glyceryl Stearate; PEG-100 Stearate; Cyclohexasiloxane; Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone; Sorbitan Stearate; Dimethicone; Polyacrylamide; C13-14 Isoparaffin; Laureth-7; Phenoxyethanol; Caprylyl Glycol; Ethylhexylglycerin; Hexylene Glycol; Imperata Cylindrica Root Extract; PEG-8; Carbomer; Triethoxysilylethyl Polydimethylsiloxyethyl Hexyl; Dimethicone; Cetyl Alcohol; Lecithin; Tocopherol; Ascorbyl Palmitate; Ascorbic Acid; Citric Acid; Xanthan Gum; Tocopheryl Linoleate/Oleate; Teprenone; Caprylic/Capric Triglyceride; Phoenix Dactylifera (Date) Fruit Extract; Polygonum Aviculare Extract; Sodium Lactate; Disodium EDTA; Dipotassium Glycyrrhizate; Arabidopsis Thaliana Extract; Plankton Extract; Micrococcus Lysate. ...

Study of Plasma Ascorbic Acid Levels in Wheezing Children  - CogprintsStudy of Plasma Ascorbic Acid Levels in Wheezing Children - Cogprints

However the ascorbic acid levels were at the lower side in female and with severe symptoms. Conclusions: Plasma Ascorbic acid ... Nagdeote, AN and Paunipagar, PV and Muddeshwar, MG and Suryawanshi, NP (2011) Study of Plasma Ascorbic Acid Levels in Wheezing ... Ascorbic acid directly neutralizes free radical and protects the bronchial tissue from oxidative injury, so it can be concluded ... The highly significant low levels of plasma ascorbic acid level in wheezing children was irrespective of sex and severity of ...
more infohttp://cogprints.org/7253/

Scurvy (Vitamin C deficiency, Ascorbic acid deficiency) - Renal and Urology NewsScurvy (Vitamin C deficiency, Ascorbic acid deficiency) - Renal and Urology News

Vitamin C or ascorbic acid is not natively synthesized by human organisms because we lack the enzyme L-gulonolactone oxidase, ... "Regulation of collagen synthesis by ascorbic acid". Proc Natl Acad Sci USA. vol. 78. 1981. pp. 2879-82. ... A concise paper describing the role of ascorbic acid in collagen synthesis.) Noble, JM, Mandel, A, Patterson, MC. "Scurvy and ... Dupertuis, YM, Ramseyer, S, Fathi, M, Pichard, C. "Assessment of ascorbic acid stability in different multilayered parenteral ...
more infohttp://www.renalandurologynews.com/dermatology/scurvy-vitamin-c-deficiency-ascorbic-acid-deficiency/article/591203/

Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea...Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea...

Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea ... Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not lipid-associated ferritin in livers of guinea ... Cham B.E., Roeser H.P. and Nikles A.C. (1990) Ascorbic acid deficiency affects the metabolism of cytosolic ferritin but not ...
more infohttps://espace.library.uq.edu.au/view/UQ:404737

Wheeler Group | Marine Biological AssociationWheeler Group | Marine Biological Association

Ascorbic acid in plants: biosynthesis and function. Crit Rev Biochem Mol Biol 2000. 35(4):291-314 ... Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis. PNAS 1999. 96:4198-4203 ... a plant ascorbic acid biosynthetic enzyme. J Biol Chem. 2006. 281(23):15662-70. ...
more infohttps://www.mba.ac.uk/fellows/wheeler-group

Serum Vitamin C Concentration Was Inversely Associated With Subsequent 20-Year Incidence of Stroke in a Japanese Rural...Serum Vitamin C Concentration Was Inversely Associated With Subsequent 20-Year Incidence of Stroke in a Japanese Rural...

The determination of ascorbic acid in small amounts of blood serum. J Biol Chem.. 1945;160:609-615. ... Ascorbic acid promotes endothelial prostacyclin,32 33 which decreases vascular tone and inhibits platelet aggregation.34 ... Serum ascorbic acid and cardiovascular disease prevalence in U.S. adults. Epidemiology.. 1998;9:316-321. ... Ascorbic acid enhances the formation of prostaglandin E1 in washed human platelets and prostacyclin in rat aortic rings. ...
more infohttp://stroke.ahajournals.org/content/31/10/2287

Ascorbic Acid: MedlinePlus Drug InformationAscorbic Acid: MedlinePlus Drug Information

Ascorbic Acid: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Before taking ascorbic acid,. *tell your doctor and pharmacist if you are allergic to ascorbic acid or any other drugs. ... Take ascorbic acid exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. ... Ascorbic acid may cause side effects. Tell your doctor if either of these symptoms is severe or does not go away: *diarrhea ...
more infohttps://medlineplus.gov/druginfo/meds/a682583.html

ascorbic acid (CHEBI:22652)ascorbic acid (CHEBI:22652)

D-ascorbic acid (CHEBI:51384) is a ascorbic acid (CHEBI:22652). D-isoascorbic acid (CHEBI:51438) is a ascorbic acid (CHEBI: ... L-ascorbic acid (CHEBI:29073) is a ascorbic acid (CHEBI:22652). L-isoascorbic acid (CHEBI:51440) is a ascorbic acid (CHEBI: ... ascorbic acid (CHEBI:22652) is a ketoaldonic acid (CHEBI:24963) ascorbic acid (CHEBI:22652) is conjugate acid of ascorbate ( ... ascorbic acid 2-sulfate (CHEBI:2869) has functional parent ascorbic acid (CHEBI:22652). ascorbic acid derivative (CHEBI:63395) ...
more infohttp://www.ebi.ac.uk/chebi/es/searchId.do?chebiId=22652

Category:Ascorbic acid - Wikimedia CommonsCategory:Ascorbic acid - Wikimedia Commons

English: This category contains pictures of ascorbic acid (vitamin C is L-ascorbic acid) and its derivatives (isoascorbic acid ... Ascorbic-acid-vs-erythorbic-acid-2D-skeletal.png 2,000 × 1,879; 94 KB. ... Media in category "Ascorbic acid". The following 109 files are in this category, out of 109 total. ... Biradik Vit C ascorbic acid german subt.png 1,372 × 441; 24 KB. ... Ascorbic-acid-from-xtal-1997-3D-balls.png 1,100 × 862; 151 KB. ...
more infohttps://commons.wikimedia.org/wiki/Category:Ascorbic_acid

Ingredient Feature: L-Ascorbic AcidIngredient Feature: L-Ascorbic Acid

L-ascorbic acid, the most widely known form of the antioxidant Vitamin C, has been described by many as the secret to flawless- ... Ingredient Feature: L-Ascorbic Acid. 09.03.2013, 11:04 CDT , Posted In: Eye Area, Prevention & Protection, Signs of Aging, ... The good news is that Obagis fan favorite, the Professional-C™ Serums, provide L-ascorbic acid in a bioavailable form for ... The function and popularity of ascorbic acid has evolved over the centuries. Its first use in the 1700s and the origin of its ...
more infohttp://www.obagi.com/patients/blog/ingredient-feature-l-ascorbic-acid?type=categories&tid=antioxidants

Ascorbic Acid News, Research - Page 2Ascorbic Acid News, Research - Page 2

Ascorbic Acid News and Research. RSS Abscorbic acid commonly known as Vitamin C is a water-soluble vitamin, which is necessary ... also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with ... Vitamin C supplementation, alone or in combination with allopurinol, appears to have a weak effect on lowering uric acid levels ...
more infohttps://www.news-medical.net/?tag=/Ascorbic-Acid&page=2

DailyMed - ASCOR- ascorbic acid injectionDailyMed - ASCOR- ascorbic acid injection

ASCORBIC ACID (UNII: PQ6CK8PD0R) (ASCORBIC ACID - UNII:PQ6CK8PD0R). ASCORBIC ACID. 500 mg in 1 mL. ... The chemical name of Ascorbic Acid is L-ascorbic acid. The molecular formula is C 6H 8O 6. It has the following structural ... Ascorbic acid (vitamin C) is present in human milk after maternal oral intake. Maternal oral intake of ascorbic acid (vitamin C ... by ascorbic acid (7.1). * ​Amphetamine and Other Drugs Affected by Urine Acidification:​ Ascorbic acid may cause acidification ...
more infohttps://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=388aad52-fc01-4784-9791-1dbc80c69306

Contraindications for Ascorbic Acid (Vitamin C) OralContraindications for Ascorbic Acid (Vitamin C) Oral

Find out what health conditions may be a health risk when taken with Ascorbic Acid (Vitamin C) Oral ... WebMD provides common contraindications for Ascorbic Acid (Vitamin C) Oral. ... Drugs & MedicationsAscorbic Acid. Who should not take Ascorbic Acid?. The following conditions are contraindicated with this ...
more infohttps://www.webmd.com/drugs/2/drug-322/ascorbic-acid-vitamin-c-oral/details/list-contraindications

Ascorbic acid in the brain.  - PubMed - NCBIAscorbic acid in the brain. - PubMed - NCBI

Ascorbic acid in the brain.. Grünewald RA1.. Author information. 1. Institute of Neurology, National Hospital for Neurology, ... Ascorbic acid is highly concentrated in the central nervous system. Measurement of the extracellular concentration of ascorbate ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/8467348

ascorbic acidascorbic acid

Below is the last interview given by Dr Linus Pauling on the virtues of ascorbic acid ... And you need lysine to be alive, it is an essential amino acid, you have to get about a gram a day to keep in protein balance, ... The answer is there is a particular amino acid in a protein in the wall of the artery - lysine, which is one of the twenty ... any physical chemist would say at once that the thing to do is to prevent that by puffing the amino acid lysine in the blood to ...
more infohttp://healthyaction.com.au/ascorbic-acid.html

ASCORBIC ACID (VITAMIN C) || Skin Deep® Cosmetics Database | EWGASCORBIC ACID (VITAMIN C) || Skin Deep® Cosmetics Database | EWG

About ASCORBIC ACID (VITAMIN C): Ascorbic acid (Vitamin C) is a naturally occurring antioxidant.. Function(s): Antioxidant; ... Synonym(s): ASCORBIC ACID, L-ASCORBIC ACID; VITAMIN C; 3-KETO-L-GULOFURANOLACTONE; 3-OXO-L-GULOFURANOLACTONE; 3-OXO-L- ...
more infohttp://www.ewg.org/skindeep/ingredient/700544/ASCORBIC_ACID_%28VITAMIN_C%29/

HISTOTOPOCHEMISTRY OF ASCORBIC ACID IN TENDON FIBRES.  - PubMed - NCBIHISTOTOPOCHEMISTRY OF ASCORBIC ACID IN TENDON FIBRES. - PubMed - NCBI

PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
more infohttps://www.ncbi.nlm.nih.gov/pubmed/14243399?dopt=Abstract

DailyMed - ASCORBIC ACID- ascorbic acid injection, solutionDailyMed - ASCORBIC ACID- ascorbic acid injection, solution

ASCORBIC ACID (UNII: PQ6CK8PD0R) (ASCORBIC ACID - UNII:PQ6CK8PD0R). ASCORBIC ACID. 500 mg in 1 mL. ... Ascorbic acid - Box 1 vial Ascorbic acid - Box 10 vials Ascorbic acid leaflet ... ASCORBIC ACID- ascorbic acid injection, solution To receive this label RSS feed. Copy the URL below and paste it into your RSS ... The chemical name of Ascorbic Acid is L-ascorbic acid. The molecular formula is C 6H 80 6 and the molecular weight is 176.13. ...
more infohttps://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1ac7a17e-75d0-4444-e054-00144ff88e88

Ascorbic Acid and Healing of Corneal Ulcers | The BMJAscorbic Acid and Healing of Corneal Ulcers | The BMJ

Ascorbic Acid and Healing of Corneal Ulcers Br Med J 1950; 2 :1145 ... Ascorbic Acid and Healing of Corneal Ulcers. Br Med J 1950; 2 doi: https://doi.org/10.1136/bmj.2.4689.1145 (Published 18 ...
more infohttp://www.bmj.com/content/2/4689/1145

Vitamin C (Ascorbic Acid) - Health LibraryVitamin C (Ascorbic Acid) - Health Library

Vitamin C, also called ascorbic acid, is a water-soluble vitamin. Water-soluble vitamins are stored in the body in very limited ... Ascorbic acid. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated July 7, 2016. Accessed July 21, ...
more infohttp://healthlibrary.epnet.com/GetContent.aspx?token=38405ca3-6cab-4817-9cba-dc64dc5c69f1&chunkiid=14069

ascorbic acid and carbonyl iron | Cignaascorbic acid and carbonyl iron | Cigna

Ascorbic acid is important for the skin and connective tissues, for normal chemical and hormonal production, and for the immune ... Ascorbic acid (vitamin C) is found in citrus fruit, tomatoes, potatoes, and leafy vegetables. ... What is ascorbic acid and carbonyl iron?. Ascorbic acid (vitamin C) is found in citrus fruit, tomatoes, potatoes, and leafy ... What other drugs will affect ascorbic acid and carbonyl iron?. Other drugs may interact with ascorbic acid and carbonyl iron, ...
more infohttps://www.cigna.com/individuals-families/health-wellness/hw/medications/ascorbic-acid-and-carbonyl-iron-d07854a1

Ascorbic acid | The Fresh LoafAscorbic acid | The Fresh Loaf

... and am wondering if the addition of ascorbic acid will help to make them lighter. Does anyone routinely use ascorbic acid in ... and am wondering if the addition of ascorbic acid will help to make them lighter. Does anyone routinely use ascorbic acid in ... ascorbic acids greater effectiveness than its mirror-image-twin ("optical isomer") erythrobic acid. For any baker of a ... Amount of ascorbic acid in flour. Ive seen it mentioned that 25ppm or so is sometimes pre-added to white flour as an improver ...
more infohttp://www.thefreshloaf.com/comment/37689

ascorbic acid - это... Что такое ascorbic acid?ascorbic acid - это... Что такое ascorbic acid?

ascorbic acid. См. витамин С. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., ... ascorbic acid - vitamin C vitamin C n. a vitamin that prevents scurvy. Also called {ascorbic acid}. Syn: ascorbic acid. [ ... ascorbic acid. ascorbic acid.. См. витамин С.. (Источник: «Англо-русский толковый словарь генетических терминов». Арефьев В.А ... ascorbic acid - [[t]æskɔ͟ː(r)bɪk æ̱sɪd[/t]] N UNCOUNT Ascorbic acid is another name for vitamin C. [TECHNICAL] Syn: vitamin C ...
more infohttps://dic.academic.ru/dic.nsf/genetics/1036/ascorbic

Ascorbic acid, tetra-TMS | C18H40O6Si4 - PubChemAscorbic acid, tetra-TMS | C18H40O6Si4 - PubChem

Ascorbic acid, tetra-TMS , C18H40O6Si4 , CID 521634 - structure, chemical names, physical and chemical properties, ...
more infohttps://pubchem.ncbi.nlm.nih.gov/compound/521634

Vitamin C (Ascorbic acid).Vitamin C (Ascorbic acid).

Vitamin C - Ascorbic acid. This very important vitamin is also known as ascorbic acid, and people report the most amazing ... Also see our more complete page on vitamin C (Ascorbic acid). Herbal information. Herbal encyclopedia ... and the conversion of cholesterol to bile acids. It enhances iron bioavailability to the body. ...
more infohttps://ageless.co.za/vitamin-c.htm

Acetaminophen-aspirin-ascorbic acid: uses & side-effects | PatientsLikeMeAcetaminophen-aspirin-ascorbic acid: uses & side-effects | PatientsLikeMe

Find the most comprehensive real-world treatment information on Acetaminophen-aspirin-ascorbic acid at PatientsLikeMe. 0 ... bipolar I disorder or psoriasis currently take Acetaminophen-aspirin-ascorbic acid. ...
more infohttps://www.patientslikeme.com/treatments/show/25110-thomapyrin-c-side-effects-and-efficacy
  • THE purpose of this paper is to present observations suggesting that ascorbic acid possesses antirheumatic activity when administered in large doses. (seanet.com)
  • Kidney stones or other very bad kidney problems have rarely happened in people taking high doses of this medicine (ascorbic acid capsules and tablets) for a long time. (drugs.com)
  • Haldane (2), taking issue with this suggestion, proposed two hypotheses: that individuals with high serum uric acid levels should show increased intellectual abilities , and that such individuals should be unusually resistant to certain types of fatigue. (drproctor.com)
  • Neither one of these has received much experimental support, although serum uric acid levels have been correlated with social class, achievement, and achievement -oriented behavior. (drproctor.com)
  • Uric acid ( along with the rest of the purines ) is also a strong electron-donor (5). (drproctor.com)
  • Ascorbic acid is an electron donor for enzymes involved in collagen hydroxylation, biosynthesis of carnitine and norepinephrine, tyrosine metabolism, and amidation of peptide hormones. (hmdb.ca)
  • A diprotic acid, such as sulfuric acid, H 2 SO 4 has two acidic hydrogen atoms. (bartleby.com)
  • For this reason, ascorbic acid is much more acidic than would be expected if the compound contained only isolated hydroxyl groups. (wikipedia.org)
  • The group D has been provided with the 150 gm of the Ascorbic acid supplement per kg of feed. (thefreedictionary.com)
  • Ascorbic acid is found naturally in citrus fruits and many vegetables and is an essential nutrient in human diets. (hmdb.ca)
  • In fact the primates, including man, are the only group whose bodies cannot make ascorbic acid. (cassiopaea.org)
  • Alopecia cell cellular disease reactive ros oxygen superoxide peroxide melanin Richard Cutler has related longevity in primates to relative levels of uric acid. (drproctor.com)
  • Primates (including humans) and a few other species in all divisions of the animal kingdom, notably the guinea pig, have lost the ability to synthesize ascorbic acid and must obtain it in their food. (hmdb.ca)
  • Ascorbic acid may interfere with laboratory tests based on oxidation-reduction reactions, including blood and urine glucose testing (5.3) . (nih.gov)
  • It is also essential for the oxidation of phenylalanine and tyrosine, and the conversion of folacin to tetrahydrofolic acid. (purebulk.com)
  • Ascorbic acid is easily destroyed by oxidation, particularly in the presence of heat and alkalinity. (purebulk.com)
  • For people who are sensitive to sour products or for those who do not like the sour taste of ascorbic acid supplements, we suggest using ascorbic acid capsules. (purebulk.com)
  • Ascorbic acid can prevent or relieve joint problems by supporting the creation of collagen‚ an essential building block of the cartilage that cushions your joints. (pureformulas.com)
  • Ascorbic acid has been shown to combat sun damage, reduce inflammation, brighten pigmentation, and stimulate new and healthy collagen formation in skin. (womenshealthmag.com)
  • Ascorbic acid is required for collagen synthesis and plays a structural role in bone, cartilage and teeth. (purebulk.com)
  • The only non-primate mammalian strain whose final purine metabolite is uric acid is the Dalmatian dog. (drproctor.com)
  • In the present study we compared the efficacies of minocycline and ascorbic acid in the life span, motor activity and lipid peroxidation in Drosophila melanogaster, in an effort to find a substance capable of providing protection against the aging associated oxidative stress. (thefreedictionary.com)
  • Ascorbic acid is important for the skin and connective tissues, for normal chemical and hormonal production, and for the immune system. (cigna.com)
  • This was the last of the compound from animal sources, but, later that year, Szent-Györgyi's group discovered that paprika pepper, a common spice in the Hungarian diet, is a rich source of hexuronic acid. (wikipedia.org)
  • In honor of the compound's antiscorbutic properties, Haworth and Szent-Györgyi now proposed the new name of "a-scorbic acid" for the compound. (wikipedia.org)
  • however, it soon became clear that other dietary acids, such as vinegar, had no such benefits. (wikipedia.org)
  • Diabetics should talk to their doctor or pharmacist for the correct way to test their urine while taking large amounts of ascorbic acid. (medlineplus.gov)
  • When I lived in France boulangers (bread bakers) were allowed to use ascorbic acid, in small amounts, in their bread baking, mostly baguettes, batards, etc. (thefreshloaf.com)
  • It is oxidized with loss of one electron to form a radical cation and then with loss of a second electron to form dehydroascorbic acid. (wikipedia.org)
  • Ascorbic acid may cause side effects. (medlineplus.gov)
  • What are the possible side effects of ascorbic acid and carbonyl iron? (cigna.com)
  • Using polyethylene glycol 3350, electrolytes, and ascorbic acid with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. (drugs.com)
  • However, after the omission of this drug and prior to treatment with ascorbic acid he had elevation of the temperature to 102° F. by rectum, several nosebleeds and a swollen painful knee. (seanet.com)
  • Treatment with ascorbic acid was begun on the evening of March 6. (seanet.com)
  • Does anyone routinely use ascorbic acid in wholemeal/spelt bread making, and if so, what is your purpose in using it. (thefreshloaf.com)
  • Route and duration of administration: Lead acetate and ascorbic acid were administered orally by gastric gavage once per day for three weeks. (thefreedictionary.com)
  • An excessive intake of ascorbic acid increases the blood supply to the ocular areas of the body. (organicfacts.net)
  • PureBulk's L-Ascorbic acid is derived from Sorbitol, derived from Glucose that is sourced from Corn and contains no fillers, additives or anti-caking agents. (purebulk.com)
  • Dr Stone's thesis is that human beings suffer from a genetic glitch that prevents us from synthesising ascorbic acid in our bodies. (cassiopaea.org)
  • However, in order to be most beneficial to the skin, it must be in the L-ascorbic form, which, while effective, is equally difficult to stabilize. (obagi.com)
  • Is this the bioactive form L-Ascorbic Acid? (purebulk.com)
  • The Bioactive form of Ascorbic acid is the L- form and is the only one currently offered at Purebulk.com. (purebulk.com)
  • In most cases when you see a product labeled as "Ascorbic acid" it is likely the L- form as the D- form and the racemic DL- form have not been as commercially available for some time. (purebulk.com)
  • If a molecule donate only one hydrogen atom then the acid is called a monoprotic acid. (bartleby.com)
  • If each molecule can donate two or more hydrogen ions, the acid is a polyprotic acid. (bartleby.com)
  • Please note that ascorbic acid is a relatively fragile molecule and it may be lost from foods during preparation, cooking, and/or storage. (purebulk.com)
  • 3 Unfortunately, once it is degraded, L-ascorbic acid can no longer carry out its beauty benefits and its effectiveness in fighting free-radical damage. (obagi.com)
  • Loss of uricase in human evolution resulted in the substituio of uric acid for ascorbic acid Syndrome x is the same as metabolic syndrome, in whic elvated levels of uric acid may play a role. (drproctor.com)
  • tell your doctor and pharmacist if you are allergic to ascorbic acid or any other drugs. (medlineplus.gov)
  • What other drugs will affect ascorbic acid and carbonyl iron? (cigna.com)
  • 10799361 ). Moreover, ascorbic acid is found to be associated with hyperoxalemia, which is an inborn error of metabolism. (hmdb.ca)
  • What should I avoid while taking ascorbic acid and carbonyl iron? (cigna.com)
  • At that time, it was ingested to treat and prevent the disease but later research showed that ascorbic acid could be helpful in cosmeceuticals as well. (obagi.com)