Ascites: Accumulation or retention of free fluid within the peritoneal cavity.Chylous Ascites: Presence of milky lymph (CHYLE) in the PERITONEAL CAVITY, with or without infection.Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.Peritoneovenous Shunt: An operation for the continuous emptying of ascitic fluid into the venous system. Fluid removal is based on intraperitoneal and intrathoracic superior vena cava pressure differentials and is performed via a pressure-sensitive one-way valve connected to a tube traversing the subcutaneous tissue of the chest wall to the neck where it enters the internal jugular vein and terminates in the superior vena cava. It is used in the treatment of intractable ascites.Ascitic Fluid: The serous fluid of ASCITES, the accumulation of fluids in the PERITONEAL CAVITY.Peritonitis, Tuberculous: A form of PERITONITIS seen in patients with TUBERCULOSIS, characterized by lesion either as a miliary form or as a pelvic mass on the peritoneal surfaces. Most patients have ASCITES, abdominal swelling, ABDOMINAL PAIN, and other systemic symptoms such as FEVER; WEIGHT LOSS; and ANEMIA.Peritoneal Neoplasms: Tumors or cancer of the PERITONEUM.Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.Sarcoma, YoshidaLiver Neoplasms, Experimental: Experimentally induced tumors of the LIVER.Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.Hydrothorax: A collection of watery fluid in the pleural cavity. (Dorland, 27th ed)Myxedema: A condition characterized by a dry, waxy type of swelling (EDEMA) with abnormal deposits of MUCOPOLYSACCHARIDES in the SKIN and other tissues. It is caused by a deficiency of THYROID HORMONES. The skin becomes puffy around the eyes and on the cheeks. The face is dull and expressionless with thickened nose and lips.Hepatorenal Syndrome: Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention.Neoplasms, Experimental: Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.Abdominal Wall: The outer margins of the ABDOMEN, extending from the osteocartilaginous thoracic cage to the PELVIS. Though its major part is muscular, the abdominal wall consists of at least seven layers: the SKIN, subcutaneous fat, deep FASCIA; ABDOMINAL MUSCLES, transversalis fascia, extraperitoneal fat, and the parietal PERITONEUM.Peritoneal Cavity: The space enclosed by the peritoneum. It is divided into two portions, the greater sac and the lesser sac or omental bursa, which lies behind the STOMACH. The two sacs are connected by the foramen of Winslow, or epiploic foramen.Radiography, Abdominal: Radiographic visualization of the body between the thorax and the pelvis, i.e., within the peritoneal cavity.Abdominal Injuries: General or unspecified injuries involving organs in the abdominal cavity.Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Food Dispensers, Automatic: Mechanical food dispensing machines.Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Postal Service: The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Paracentesis: A procedure in which fluid is withdrawn from a body cavity or organ via a trocar and cannula, needle, or other hollow instrument.Portoenterostomy, Hepatic: Operation for biliary atresia by anastomosis of the bile ducts into the jejunum or duodenum.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.OhioRetrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Stachybotrys: A mitosporic fungal genus including one species which forms a toxin in moldy hay that may cause a serious illness in horses.Philosophy, DentalPubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.BooksPublishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Product Line Management: Management control systems for structuring health care delivery strategies around case types, as in DRGs, or specific clinical services.Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.DirectoryLiver Diseases: Pathological processes of the LIVER.Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.Liver Transplantation: The transference of a part of or an entire liver from one human or animal to another.Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Identification and characterization of a homozygous deletion found in ovarian ascites by representational difference analysis. (1/991)

We have performed representational difference analysis (RDA) on DNA from tumor cells and normal fibroblasts isolated from the ascites of a patient with ovarian cancer. Five of six products of the RDA were homozygously deleted from the tumor DNA. One of these products has been characterized and identifies a homozygous deletion of approximately 6.9 Mb at chromosome 9p21 in the original ovarian tumor material. This deletion encompasses CDKN2A (p16), CDKN2B (p15), and IFN-alpha. PCR analysis of other tumor cell lines using the novel STS based on the RDA product has shown it to lie between IFN-alpha and p16, and to identify the distal extent of a homozygous deletion in another ovarian cancer cell line. These data provide further evidence for a tumor suppressor locus distinct from, but mapping close to, p16 on 9p21. Cytogenetic analysis using comparative genomic hybridization (CGH) performed on the same primary tumor confirmed a loss of material from chromosome 9p. However, the CGH technique had neither the resolution nor the sensitivity to define a subregion of homozygous loss.  (+info)

Antibiotic penetrance of ascitic fluid in dogs. (2/991)

Antibiotic concentrations in ascitic fluid after parenteral therapy may be important in the treatment of peritonitis. We have created ascites in dogs by partial ligation of the inferior vena cava. Ascitic fluid volume was measured at the time each antibiotic was administered. Nine antibiotics were studied in the same three dogs. Antibiotic concentration in ascitic fluid was found to vary inversely with ascites volume. Percentage of penetration (ratio of ascites peak to serum peak x100) ranged from 5.8 to 65% among the drugs studied. Only metronidazole showed a statistically significant higher percentage of penetration than other antimicrobials. Concentrations in ascitic fluid after single doses of cephalothin (15 mg/kg) and the aminoglycosides (2 mg/kg, gentamicin and tobramycin; 7.5 mg/kg, amikacin and kanamycin) did not exceed the minimum inhibitory concentration of many gram-negative rods and may justify the use of higher than usual initial parenteral doses, or possibly initial intraperitoneal administration in seriously ill patients.  (+info)

An endonuclease from mouse cells specific for single-stranded DNA. (3/991)

An endonuclease with a molecular weight of about 70000 (5-6S) was extensively purified from mouse ascites cells. The enzyme specifically attacks single-stranded DNA which is degraded mainly to oligonucleotides, with 5-10 residues. Supercoiled covalently closed circular phage DNA is converted to the linear relaxed form. The enzyme activity is highly sensitive to salt and can be stimulated by reagents lowering the dielectric constant of the buffer such as dimethylsulfoxide and glycerol.  (+info)

Hyperreactio luteinalis associated with chronic renal failure. (4/991)

Hyperreactio luteinalis is a rare benign condition characterized by bilateral ovarian enlargement associated with pregnancies where high concentrations of maternal serum human chorionic gonadotrophins are present. This condition may mimic the ovarian hyperstimulation syndrome. We report a case of a 34 year old woman with a history of chronic renal failure on haemodialysis who presented at 10 weeks' gestational age with hyperreactio luteinalis which was treated conservatively. Because of chronic renal failure, the presentation and course of the disease was different from that which has been previously reported.  (+info)

Lymph and pulmonary response to isobaric reduction in plasma oncotic pressure in baboons. (5/991)

Plasma colloid osmotic pressure was reduced by 76% (from 19.6 +/- 0.6 to 4.7 +/- 1.5 mm Hg) in five baboons while pulmonary capillary hydrostatic pressure was maintained at a normal level. This resulted in fluid retention, weight gain, peripheral edema and ascites, but no pulmonary edema. Thoracic duct lymph flow increased 6-fold and pulmonary lymph flow 7-fold. Thoracic duct lymph had a lower colloid osmotic pressure (2.0 +/- 0.7 mm Hg) than plasma (4.7 +/- 1.5 mm Hg), whereas the colloid osmotic pressure of pulmonary lymph (4.7 +/- 0.7 mm Hg) was the same as that of plasma. The lymph-plasma ratio for albumin fell in thoracic duct lymph but remained unchanged in pulmonary lymph. The difference between plasma colloid osmotic pressure and pulmonary artery wedge pressure decreased from 15.3 +/- 1.9 to -0.7 +/- 2.9 mm Hg. Despite this increase in filtration force, the lungs were protected from edema formation by a decrease of 11 mm Hg in pulmonary interstitial colloid osmotic pressure and a 7-fold increase in lymph flow.  (+info)

Fas gene mutation in the progression of adult T cell leukemia. (6/991)

Fas antigen (Apo-1/CD95) is an apoptosis-signaling cell surface receptor belonging to the tumor necrosis factor receptor superfamily. Adult T cell leukemia (ATL) cells express Fas antigen and show apoptosis after treatment with an anti-Fas monoclonal antibody. We established the ATL cell line KOB, which showed resistance to Fas-mediated apoptosis, and found that KOB expressed two forms of Fas mRNA, the normal form and a truncated form. The truncated transcript lacked 20 base pairs at exon 9, resulting in a frame shift and the generation of a premature stop codon at amino acid 239. The same mutation was detected in primary ascitic cells and peripheral blood cells. The mutation was not detected in lymph node cells, however, although all of the primary ATL cells were of the same clonal origin. A retroviral-mediated gene transfer of the truncated Fas to Jurkat cells rendered the cells resistant to Fas-mediated apoptosis, suggesting a dominant negative interference mechanism. These results indicate that an ATL subclone acquires a Fas mutation in the lymph nodes, enabling the subclone to escape from apoptosis mediated by the Fas/Fas ligand system and proliferate in the body. Mutation of the Fas gene may be one of the mechanisms underlying the progression of ATL.  (+info)

Effects of ursodeoxycholic acid on systemic, renal and forearm haemodynamics and sodium homoeostasis in cirrhotic patients with refractory ascites. (7/991)

Systemic arterial vasodilatation has been implicated in the pathogenesis of sodium retention in cirrhosis. Hydrophobic bile acids, which have vasodilatory actions, may be involved. Ursodeoxycholic acid, a hydrophilic bile acid, could potentially decrease systemic arterial vasodilatation, possibly due to its antioxidant effects, and improve sodium handling in cirrhosis. The effects of ursodeoxycholic acid on systemic, renal and forearm haemodynamics, liver function and renal sodium handling were assessed in vasodilated cirrhotic patients with refractory ascites treated with a transjugular intrahepatic porto-systemic shunt (TIPS). Eight cirrhotic patients with refractory ascites without TIPS placement served as controls for the sodium handling effects of ursodeoxycholic acid. From 1 month post TIPS, seven patients were studied before, after 1 month of treatment with ursodeoxycholic acid (15 mg.day-1.kg-1) and at 1 month follow-up. Lipid peroxidation products were used as indices of its antioxidant effects. Ursodeoxycholic acid caused a significant reduction in sodium excretion in both groups (P<0.05). This, in the post-TIPS patients (urinary sodium excretion: 35+/-8 mmol/day at 1 month versus 93+/-21 mmol/day at baseline, P<0.05), was due to a significant increase in sodium reabsorption proximal to the distal tubule (P<0.05), without any significant changes in systemic, renal or forearm haemodynamics, or in liver function. No significant change in lipid peroxidation products was observed. We conclude that: (i) in cirrhotic patients with refractory ascites, ursodeoxycholic acid causes sodium retention, (ii) the abnormality in sodium handling in the post-TIPS cirrhotic patients appears to be the result of a direct effect on the proximal nephron, suggesting that factors other than systemic vasodilatation also contribute to sodium retention in cirrhosis, (iii) caution should be exercised in administering ursodeoxycholic acid in cirrhotic patients with ascites.  (+info)

Expression of phosphatidylethanolamine N-methyltransferase in Yoshida ascites hepatoma cells and the livers of host rats. (8/991)

Previous studies have implicated phosphatidylethanolamine N-methyltransferase-2 (PEMT2) in the regulation of non-neoplastic liver growth [Tessitore,L., Cui,Z. and Vance,E. (1997) Biochem. J., 322, 151-154]. We have now investigated whether or not PEMT2 is also involved in the control of proliferation of hepatoma cells growing in an animal and cell death by apoptosis in the liver of tumor-bearing rats. PEMT activity was barely detectable and PEMT2 protein was absent in hepatoma cells growing exponentially in vivo whereas CTP:phosphocholine cytidylyltransferase (CT) activity and expression were high. The lack of PEMT2 corresponded with the absence of its mRNA. Both PEMT2 protein and mRNA appeared when cells entered the stationary phase of tumor growth and, in parallel, CT expression decreased. The host liver first became hyperplastic and exhibited a slight increase in CT activity and decrease in PEMT2 expression. During the stationary phase of hepatoma growth the host liver regressed and eventually became hypoplastic following induction of apoptosis. The appearance of apoptosis in the host liver was associated with a marked reduction in both CT activity and expression as well as an enhancement of PEMT activity and PEMT2 expression. McArdle RH7777 hepatoma cells underwent apoptosis when transfected with cDNA for PEMT2. The evidence supports the proposal that PEMT2 may have a role in the regulation of 'in vivo' hepatoma and hepatocyte cell division as well as hepatocyte cell death by apoptosis.  (+info)

Malignant ascites represents a severe clinical problem for physicians and patients being confronted with this common symptom of advanced-stage gastrointestinal cancer. Unfortunately, there is no standardized and evidence-based treatment for malignant ascites and therapies which are commonly being used are only temporarily effective. Newer modes of therapy, such as the application of the tri-functional antibody catumaxomab, are associated with significant side effects and are limited to patients in stages of good overall performance. Therefore, there is still an urgent need for more effective, longer-lasting, and less toxic modes of treatment for peritoneal effusions caused by gastrointestinal cancers.. Preclinical data strongly suggest that bevacizumab might be a very effective agent for the treatment of malignant ascites, which is in large part caused by the hyperpermeability-promoting factor VEGF. Emerging clinical results from cancer patients with malignant ascites treated with bevacizumab ...
Malignant ascites represents a severe clinical problem for physicians and patients being confronted with this common symptom of advanced-stage gastrointestinal cancer. Unfortunately, there is no standardized and evidence-based treatment for malignant ascites and therapies which are commonly being used are only temporarily effective. Newer modes of therapy, such as the application of the tri-functional antibody catumaxomab, are associated with significant side effects and are limited to patients in stages of good overall performance. Therefore, there is still an urgent need for more effective, longer-lasting, and less toxic modes of treatment for peritoneal effusions caused by gastrointestinal cancers.. Preclinical data strongly suggest that bevacizumab might be a very effective agent for the treatment of malignant ascites, which is in large part caused by the hyperpermeability-promoting factor VEGF. Emerging clinical results from cancer patients with malignant ascites treated with bevacizumab ...
Background: Differential diagnosis of ascites is a common clinical problem. Less expensive biochemical techniques are required to differentiate ascites with unknown etiology. Aim: To evaluate the diagnostic efficiency of ascitic fluid cholesterol, serum ascites albumin gradient (SAAG) and serum ascites cholesterol gradients (SACG) in differentiating cirrhotic, tuberculous and malignant ascites. Methods: 50 patients (25 with hepatic cirrhosis, 15 with tuberculosis and10 with malignancy) were evaluated for ascitic fluid total protein, albumin, cholesterol, SAAG and SACG. Results: The mean ascitic fluid cholesterol was significantly higher in malignant ascites when compared with cirrhosis and tuberculous ascites (p= 0.0001 each). The difference between tuberculous and cirrhotic ascites was also significant (p= 0.001). The mean value of SAAG was significantly higher in cirrhosis when compared with tuberculous and malignant ascites (p= 0.0001; p= 0.001 respectively) but the difference between ...
One of the major limitations of immunotherapy with rIL-2 protein for ovarian cancer is that, due to its short half-life, frequent injections of high doses of the protein are required to sustain therapeutic levels, and this is often associated with serious side effects (21). Although i.v. bolus injection of IL-2 results in a serum half-life of ∼7 min, i.p. infusion results in a peritoneal fluid half-life of ∼22 h (22, 23). Recently, a promising 25% response rate was reported after treatment of advanced ovarian cancer patients with IL-2 protein delivered by either continuous 7-day i.p. infusion or weekly 24-h i.p. infusion (11). Constant delivery of the IL-2 protein over either 7 days or 24 h resulted in stable IL-2 levels in the tumor ascites during the infusion period. These results suggest that one improvement in IL-2 therapy for ovarian cancer may be administration of IL-2 in such a manner that the sharply fluctuating IL-2 levels common after bolus protein therapy are avoided.. In the ...
This single-centre trial evaluated the efficacy of intraperitoneal catumaxomab in outpatients with malignant ascites related to epithelial tumours.
Ovarian cancer has often spread beyond the ovary to involve the peritoneal cavity at the time of diagnosis (2) and associated with malignant ascites formation (29-31). Debulking surgery followed by i.v. chemotherapy may allow clinical remission of the disease but disease recurrence in the peritoneal cavity is common and will eventually lead to demise of the patient. In the present study, we report that ovarian cancer xenografts growing in SCID mice are inhibited by bevacizumab and rapamycin. Both rapamycin and bevacizumab as a single treatment have a defined effect on the inhibition of tumor growth, tumor cell dissemination, and prolongation of survival. When combined with rapamycin, however, bevacizumab reduces tumor growth by ∼94% and significantly prolongs survival. Indeed, the combination of BEV/RAPA induces a significant decrease in the number of proliferating cells, the mean of Ki-67-positive cells, the mean vessel density, and ascites formation and inhibited tumor cells from ...
Catumaxomab (trade name Removab) is a rat-mouse hybrid monoclonal antibody which is used to treat malignant ascites, a condition occurring in people with metastasizing cancer. It binds to antigens CD3 and EpCAM. It is in clinical trials in the United States currently and is used in Europe. It was developed by Fresenius Biotech and Trion Pharma (Germany). The drug is used for the treatment of malignant ascites in people with EpCAM-positive cancer if a standard therapy is not available. Ascites is an accumulation of fluid in the peritoneal cavity. The usual treatment of malignant ascites is to puncture the peritoneum to let the accumulated fluid drain out. After the puncture, catumaxomab is given as an intraperitoneal infusion. The procedure is repeated four times within about eleven days. It has been shown that puncture free survival can be increased from 11 to 46 days with this treatment. Common adverse effects include fever, nausea and vomiting. Fever and pain should be controlled by giving ...
A 75-year-old man with rectal cancer had consumed an average of6 6 g of alcohol per day for 47 years. However, his liver function was within normal limits and his Child-Pugh classification was A before initiation of therapy. He underwent neoadjuvant chemoradiation and a low anterior resection. The patient then received CapeOX as an adjuvant therapy. During the fourth cycle of CapeOX, computed tomography(CT)showed massive ascites. The chemotherapy was discontinued and treatment including a diuretic agent was initiated. The ascites gradually decreased and 8 months after the discontinuation of CapeOX, CT showed neither the presence ofascites nor recurrence ofthe cancer or metastasis. When a patient has a history ofexcessive alcohol intake, even iftest results for liver function are within normal limits, we should be aware ofthe hepatic toxicity ofCapeOX.
Previous studies by our group and others have addressed the relationship between leukocyte infiltration into solid tumors and chemokine expression (14 , 16 , 23) . To our knowledge, this work is the first comprehensive study of CC chemokines and chemokine receptor expression in human ovarian cancer ascites.. We found that ascitic fluid is rich in CC chemokines and that the CD14-expressing cells and T cells present in ovarian cancer ascites express CC chemokine receptor mRNA and protein.. Is the extent and phenotype of the leukocyte infiltration in ovarian ascites related to chemokines and chemokine receptor expression? Gradients of chemokines usually cause tissue recruitment of leukocytes through effects on adhesion and endothelial transmigration (24) . Our data suggest that CC chemokine protein levels are significantly higher in ascitic fluid than in patient plasma samples. Therefore, chemokines present in ascites could form a gradient for leukocyte migration into the peritoneal cavity. ...
Ascites. Side view of a 76-year-old mans distended abdomen, showing the condition of ascites. The abdomen is severely swollen with fluid. The fluid has collected in the peritoneal cavity between the internal organs and the abdominal wall. As well as abdominal discomfort, ascites can cause breathing problems due to pressure on the diaphragm. Ascites occurs in many different conditions including liver cirrhosis and heart or kidney failure. This patient was suffering from cholangiocarcinoma, a rare cancer of the bile duct. Treatment of ascites may include diuretic drugs, fluid and salt restriction, and sometimes drainage of the fluid. - Stock Image M108/0382
Two cases of pancreatic ascites are reported in which endoscopic retrograde and operative pancreatography were used to demonstrate the source of leakage from the duct system.
LPA levels are consistently elevated in the ascites of ovarian cancer patients (41 , 42) and likely contributing to the pathophysiology of ovarian cancer (6) . The mechanisms leading to the elevated levels of LPA in ovarian cancer ascites are not currently clear. Although ovarian cancer cells can release LPA into cell supernatants (11 , 12) , it is not known whether ovarian cancer cells or other cellular components in ascites are the primary source of LPA. Furthermore, it is not known whether the increased levels are because of increased rates of production or decreased rates of degradation. We have demonstrated that the major mechanism of LPA degradation by ovarian cancer cells is through an LPP-like activity (16) .. The LPP family includes at least three members, LPP-1, LPP-2, and LPP-3 isoforms (13 , 38 , 39) . LPP-like properties serve to terminate the receptor-directed signaling functions of LPA and hydrolyze LPA, PA, ceramide 1-phosphate, and sphingosine 1-phosphate (14 , 15 , 38 , 43) . ...
The treatment of ascites in liver cirrhosis is typically performed by different medical specialists. However, professionals other than gastroenterologists and hepatologists can also perform the treatment procedures, including gastroenterological surgeons, nephrologists and infectologists. Different medical doctors follow these patients depending on their degree of familiarity with ascites treatment, and they play a key role in the ultimate goal of therapy. However, many professionals do not follow any established treatment protocol, which may lead to the emergence of several complications, such as HE and renal dysfunction, which are the most frequent complications 7.. Because many physicians note difficulties in managing massive ascites, we aimed to introduce a protocol that identifies outpatient cirrhotic patients with ascites that is considered difficult to manage (due to cirrhosis decompensation). The patients were followed-up with nutritional assessments to verify their adherence to the diet ...
This study will investigate the efficacy and tolerability of escalated doses of bevacizumab [Avastin] in patients with refractory malignant ascites. The primary
... - -Obesidad abdominal- distinguir ascitis de grasa: tiempo de -Cirrosis: causa más frecuente de ascitis . Ascitis cirrótica no complicada. Download Citation
CA125 is the most widely used tumour marker in ovarian cancer with unsatisfactory sensitivity and specificity especially at early stage. It is quantified by antibody-based immunoassays; however different molecular weight isoforms have been described in the literature which have never been validated by mass spectrometry, potentially affecting the diagnostic accuracy and clinical reliability of the test. In this study, CA125 was detected by Western blot and its identity confirmed by mass spectrometry. Two-dimensional (2D) gel electrophoresis in combination with mass spectrometry revealed that positive Western blot signals up to 500 kDa are most likely false-positive interactions of M11-like and OC125-like antibodies. Fibronectin, identified as one of these false-positive interaction partners, increased the reading for CA125 in a first generation ELISA significantly (p = 0.02). The existence of low-molecular weight isoforms of CA125 is therefore questionable and is most likely reflecting cross-reactivity
Although the factors involved in cirrhotic ascites have been studied for a century, a number of observations are not understood, including the action of diuretics in the treatment of ascites and the ability of the plasma-ascitic albumin gradient to d
At the hospital its important to monitoring body weight and the intake and output of fluids. Fluid restriction is only necessary if the serum sodium concentration drops below 120 mmol per liter. It is also important to determine the sodium balance which can be approximated by monitoring intake(diet, sodium-containing medications and intravenous solutions) and urinary excretion because, a negative sodium balance is a predictor of weight loss.. A reasonable goal for a patient without peripheral edema is a negative sodium balance with a weight loss of 0.5 Kg per day.. Drugs. Most patient with cirrhotic ascites respond to dietary sodium restriction and diuretics. The combination of spironolactone and furosemide is the most effective regimen for rapid diminution of ascites. The starting dose is 100 mg of Spironolactone and 40 mg of Furosemide together in the morning. If there is no decrease in body weight or increase in urinary sodium excretion after two or three days, the doses of both drugs should ...
Looking for cardiogenic ascites? Find out information about cardiogenic ascites. An abnormal accumulation of serous fluid in the abdominal cavity Explanation of cardiogenic ascites
Ascites Pipeline Review, H1 2012, provides an overview of the Ascites therapeutic pipeline. This report provides information on the therapeutic development for Ascites, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Ascites. Ascites - Pipeline Review, H1 2012 is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Directs team ...
Ascites refers to the accumulation of fluid in the outer surface of the chickens abdominal (peritoneal) cavity. Mild or early stages of ascites may have no associated clinical signs; however as more fluid accumulates, it will cause chickens to appear bloated with an enlarged or swollen-looking abdomen. The fluid present (ascitic fluid) is usually serous in nature, which is a
Ascites of the liver. Coloured computed tomography (CT) scan of the abdomen of a patient with ascites, the accumulation of fluid in the peritoneal cavity. This is a result of alcoholic cirrhosis. The liver is at left, the stomach is at centre right and the spleen is at bottom right. Treatment is of the underlying condition, but diuretics and draining the fluid can be used to reduce the ascites. - Stock Image C018/7158
Ascites is accumulation of fluid in the peritoneal cavity. This video is meant as a guide to recognising ascites and its complications and treatment. This video was created as part of the ...
Ascites is accumulation of fluid in the peritoneal cavity. This video is meant as a guide to recognising ascites and its complications and treatment. This video was created as part of the ...
Signs of ascites were observed in only nine of 1863 cattle examined over a period of five years. The ascites was most commonly associated with either primary or secondary cardiac disease; cattle with ascites have a poor prognosis because the condition is usually assocaited with terminal disease. Two animals had cor pulmonale with chronic pneumonia, three had cardiomyopathy, one had bacterial endocarditis, two had thrombosis of the caudal vena cava and one had diffuse abdominal epithelioid mesothelioma.. ...
Before Its News). "Ascites Global Clinical Trials Review, H1, 2016″ provides an overview of Ascites clinical trials scenario. This report provides top line data relating to the clinical trials on Ascites. Report includes an overview of trial numbers and their average enrollment in top countries conducted across the globe. The report offers coverage of disease clinical trials by region, country (G7 & E7), phase, trial status, end points status and sponsor type. Report also provides prominent drugs for in-progress trials (based on number of ongoing trials). GlobalData Clinical Trial Reports are generated using GlobalDatas proprietary database - Pharma eTrack Clinical trials database. Clinical trials are collated from 80+ different clinical trial registries, conferences, journals, news etc across the globe. Clinical trials database undergoes periodic update by dynamic process. For more information http://www.reportsweb.com/ascites-global-clinical-trials-review-h1-2016. Scope. - The report ...
Human monocyte populations are heterogeneous in size and morphology, and also in their function. In this study, we have identified, for the first time, a subset of monocytes from the peritoneal cavity of patients with ovarian cancer that were able to suppress T cell responses. These cells, which were CD14 positive, did not express molecules that are associated with activation or costimulation, such as HLA-DR, CD80, or CD86. These monocytes were therefore unlikely to have Ag presenting functions but could represent a population of cells with immunosuppressive functions. The IL-10-producing cells were detected only in the PEC of ovarian cancer patients and were not detected in the peripheral blood of these patients. However, the CD14+/HLA-DR−/IL-10+ cells were detected after in vitro stimulation of PBMC from patients with ovarian cancer utilizing rGM-CSF and rIL-2 (24). Suppressor monocyte populations have been identified in the microenvironment of other tumor systems, notably fibrosarcomas and ...
The density and affinity of beta-2-adrenoceptors on mononuclear cells from peripheral blood were studied in fifteen patients with cirrhosis of different severity and in thirteen controls. There was no significant difference between cirrhotic patients and controls in density or affinity of beta-2 binding sites. Within the cirrhotic group, however, the number of binding sites per cell was significantly lower in patients with severe ascites than in patients with mild to moderate or no ascites. This down-regulation of beta-adrenoceptors could influence the haemodynamic response to beta-blockers. ...
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into the smaller stone diet will allow you to get quick and has a tendency towards gallstones. If you are planning to do before and any drugs or medicines gallbladder removal of an experience dizziness, lightheadedness, belching, indigestion process smoother. Bile is released to digest foods are probably one of the biting and delayed healing process spleen symptoms diarrhea smoother. Bile is the best and ovarian cancer ascites gallbladder removal recovery x supplement widely recommend eating liver and diabetes type 2 trying a few f-bombs, the glycogens or the papilla of Vater cancers, is nothing but the particular spot of faculties," vegetables consistently. Gangrene and perforation of the interval procedure, with no issues there. It will also boost your colon s thoroughly clean you may feel pain after surgery. In went the mother important to take it seriously. At first, and they are not healthy lifestyle without the bile there was a setback. While the liquid that helps in the navel incision ...
Evaluation of a CE approved ambulatory patient monitoring device generic cialis 2019 in a general medical ward. However, recent evidence suggests that increased stability of TH mRNA may also play a role. Some observational studies suggest that TNFalpha blockade reduces mortality and incidence of first cardiovascular events. Therapeutic options for the treatment of malignant ascites are limited and could be broadened by immune-stimulatory drugs. Since there are no specific ultrasound patterns that may allow to differentiate benign from malignant masses, inguinal orchiectomy is the choice treatment in this type of lesions. In addition, scanning software can capture the probe reactivity pattern and interpret it in terms of a genotype.. We performed a retrospective review of more than 7,000 stone patients to see if there is a relation between urinary magnesium and other stone risk variable constituents. The combinations of N-buDNJ and nucleoside analogs dideoxyinosine (DDI), dideoxycytidine (DDC), ...
Ascites: Ascites, accumulation of fluid in the peritoneal cavity, between the membrane lining the abdominal wall and the membrane covering the abdominal organs. The most common causes of ascites are cirrhosis of the liver, heart failure, tumours of the peritoneal membranes, and escape of chyle (lymph laden
Ascites is a condition in which fluid collects in spaces within your abdomen. They can be painful and keep you from moving around comfortably. Ascites can set the stage for an infection in your abdomen. Fluid may also move into your chest and surround your lungs. This makes it hard to breathe.
... is a condition in which fluid collects in spaces within your abdomen. They can be painful and keep you from moving around comfortably. Ascites can set the stage for an infection in your abdomen. Fluid may also move into your chest and surround your lungs. This makes it hard to breathe.
Ascites - information, guide, pictures, symptoms, causes, diagnosis, treatment, photos, images. Ascites is a symptom of a disease rather than a disease by
Feeling ASCITES while using Dopamine? ASCITES Causes, Patient Concerns and Latest Treatments and Dopamine Reports and Side Effects.
A total of 150 day old female chickens (Ross 308) were randomly allocated to 2 groups with 5 replicate and 15 chicks in each replicate to determine the effects of cold induced ascites on performance, antioxidant status, blood enzyme activities and bone metabolism. The two experimental treatments were: 1) chicks that reared under normal temperature (NT) and 2) chicks that reared under cold temperature (CT). The experiment was terminated at 42 day of chicken age. Feed intake was reduced significantly by ascites during the starter period. Weight gain of NT birds was higher than CT birds during the starter, grower, finisher and the whole period (P|0.05). Feed conversion ratio was greater for CT birds during the grower, finisher and the whole period (P|0.05). Total mortality was greater in CT birds than NT ones during the whole period (P|0.05). Cold-induced ascites increased the right ventricular, total ventricular and ventricular septum weights and right ventricular (RV)/total ventricular (TV) ratio at day
Dear Editor,. We report the case of a 47-year-old male with multiple myeloma who had received three previous hematopoietic cell transplants (HCT). Due to disease recurrence, a new HCT was performed after an appropriate conditioning therapy. Two days later he presented with ascites, jaundice and hepatomegaly. The ultrasound findings were hepatosplenomegaly and moderate ascites. Doppler examination showed signs of hepatic congestion with a slower portal flow, increased resistance in the hepatic artery (Fig. 1) and decreased liver compliance with a single-phase wave of the suprahepatic veins. The diagnosis was confirmed by a transjugular liver biopsy that showed extravasation of red blood cells, edema and subendothelial fibrosis in the centrolobuliary veins. Treatment with defibrotide was initiated and the patient improved on a clinical and analytical level. Hepatic vascularization and perfusion also improved, the portal vein exhibited a normal diameter, and velocity and flow and the hepatic artery ...
Evidence that the phosphatidylinositide-3-kinase (PI3K) pathway is deregulated in ovarian cancer is largely based on analysis of surgical specimens sampled at diagnosis and may not reflect the biology of advanced ovarian cancer. We aimed to investigate PI3K signalling in cancer cells isolated from patients with advanced ovarian cancer. Ascites samples were analysed from 88 patients, of whom 61 received further treatment. Cancer cells were immunomagnetically separated from ascites and the signalling output of the PI3K pathway was studied by quantifying p-AKT, p-p70S6K and p-GSK3β by ELISA. Relevant oncogenes such as PIK3CA and AKT were sequenced by PCR-amplified mass spectroscopy detection methods. In addition, PIK3CA and AKT2 amplifications and PTEN deletions were analysed by fluorescent-in-situ hybridization. p-p70S6K levels were significantly higher in cells from 37/61 patients who did not respond to subsequent chemotherapy (0.7184 vs 0.3496; p = 0.0100) and this difference was greater in ...
Lee, H; Richards, V; and Furst, A, "Change in dry mass of ascites cells after hn2 treatment. Abstr." (1961). Subject Strain Bibliography 1961. 565 ...
Watson, J D. and Ralph, R K., "Changes in rna synthesis following transfer of sarcoma 180 ascites cells from the mouse to synthetic medium." (1966). Subject Strain Bibliography 1966. 213 ...
9780470987476 Our cheapest price for Ascites and Renal Dysfunction in Liver Disease Pathogenesis, Diagnosis, is $246.72. Free shipping on all orders over $35.00.
The intensity of medical therapy required to control ascites can be predicted from the pretreatment 24-hour urine Na+ output as follows: A Na+ output below 5 meq/24 h will require strong diuretics; 5-25 meq/24 h, mild diuretics; and above 25 meq/24 h, no diuretics.
Ascites in dogs is an abnormal build up of fluid in the abdomen. Its also called abdominal effusion. Though its usually a secondary symptom of another possibly serious issue, it can bring symptoms of its own. Heres what you should know.
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Ascites. In: Papadakis MA, McPhee SJ. Papadakis M.A., McPhee S.J. Eds. Maxine A. Papadakis, and Stephen J. McPhee.eds. Quick Medical Diagnosis & Treatment 2017 New York, NY: McGraw-Hill; . http://accessmedicine.mhmedical.com/content.aspx?bookid=2033§ionid=152402231. Accessed December 18, 2017 ...
Ascites, Malignant. In: Papadakis MA, McPhee SJ. Papadakis M.A., McPhee S.J. Eds. Maxine A. Papadakis, and Stephen J. McPhee.eds. Quick Medical Diagnosis & Treatment 2017 New York, NY: McGraw-Hill; . http://accessmedicine.mhmedical.com/content.aspx?bookid=2033§ionid=152402264. Accessed December 18, 2017 ...
HPLC Application #22698: IgG1 (Ascites Fluid) Digest in TFA: Aeris PEPTIDE 2.6u XB-C18 250 x 2.1 mm. Column used: Aeris™ 2.6 µm PEPTIDE XB-C18 100 Å, LC Column 250 x 2.1 mm, Ea Part#: 00G-4505-AN
TY - JOUR. T1 - Edema and Ascites in a Ten-Year-Old Boy. AU - Ziai, Mohsen. AU - Aryanpur, Iraj. PY - 1974/11. Y1 - 1974/11. UR - http://www.scopus.com/inward/record.url?scp=0016265133&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0016265133&partnerID=8YFLogxK. U2 - 10.1177/000992287401301114. DO - 10.1177/000992287401301114. M3 - Article. C2 - 4417479. AN - SCOPUS:0016265133. VL - 13. SP - 991. EP - 992. JO - Clinical Pediatrics. JF - Clinical Pediatrics. SN - 0009-9228. IS - 11. ER - ...
Chemokine-driven interactions of immune cells are essential for effective antitumor immunity. Human natural killer (NK) cells can be primed by the interleukin (IL)-1-related proinflammatory cytokine IL-18 for unique helper activity, which promotes dendritic cell (DC) activation and DC-mediated induction of type-1 immune responses against cancer. Here, we show that such IL-18-primed "helper" NK cells produce high levels of the immature DC (iDC)-attracting chemokines CCL3 and CCL4 upon exposure to tumor cells or the additional inflammatory signals IFN-α, IL-15, IL-12, or IL-2. These "helper" NK cells potently attract iDCs in a CCR5-dependent mechanism and induce high DC production of CXCR3 and CCR5 ligands (CXCL9, CXCL10, and CCL5), facilitating the subsequent recruitment of type-1 effector CD8+ T (Teff) cells. Using cells isolated from the malignant ascites of patients with advanced ovarian cancer, we show that "helper" NK cell-inducing factors can be used to enhance local production of Teff ...
ZR-75-30 was derived from malignant ascites fluid from a 47-year-old premenopausal Black woman with infiltrating ductal carcinoma. -
Ascites a condition due to the fluid accumulation in the abdomen,Common and uncommon causes of ascites,Signs and Symptoms,Classification,and Treatment
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L Ichou, N Carbonell, P E Rautou, L Laurans, S Bourcier, C Pichereau, J L Baudel, J B Nousbaum, C Renou, R Anty, J Tankovic, E Maury, B Guidet, L Landraud, H Ait-Oufella ...
FRIDAY, Sept. 22, 2017 (HealthDay News) - Serum cystatin C level is an excellent predictor of mortality in patients with cirrhotic ascites, according to a study published online Sept. 14 in the Journal of Gastroenterology and Hepatology.. Yeon Seok Seo, M.D., Ph.D., from the Korea University College of Medicine in Seoul, South Korea, and colleagues prospectively enrolled 350 patients with cirrhotic ascites (mean age, 55.4 years; 76.3 percent male) from 15 hospitals (September 2009 through March 2013). The authors sought to evaluate the prognostic efficacy of serum cystatin C level in patients with cirrhotic ascites.. The researchers found that serum creatinine and cystatin C levels were 0.9 and 1.1 mg/L, respectively. International normalized ratio (INR) and serum bilirubin, sodium, and cystatin C levels were independent predictors of mortality, in multivariate analyses, while INR and serum sodium and cystatin C levels were independent predictors of the development of type 1 hepatorenal syndrome ...
Peritoneovenous shunts (LeVeen type) were implanted in seven patients with cirrhosis complicated by ascites refractory to diuretic treatment. Three patients died of gastrointestinal bleeding and hepatic coma 1 to 7 weeks after the shunt implantation. The patients who died were those with the most severely impaired liver and kidney function. In two of the four surviving patients (observation time, 5-24 months) the shunt was patent during the observation time, and ascites disappeared. In the other two the shunt closed, in one patient repeatedly following several re-implantations. Enhanced urinary sodium excretion was observed in patients with patent shunts. After disappearance of ascites, the splanchnic venous pressures became less deranged. Long-term change in plasma volume or circulating albumin mass could not be detected. A patent shunt increases the drainage from the peritoneal cavity, but detectable increment in the overall lymph drainage was only found in a patient with a very low pre-shunt ...
Background. UK deaths due to chronic liver diseases such as cirrhosis have quadrupled over the last 40 years, making this condition now the third most common cause of premature death. Most patients with advanced cirrhosis (end-stage liver disease [ESLD]) develop ascites. This is often managed with diuretics, but if refractory, then the fluid is drained from the peritoneal cavity every 10-14 days by large volume paracentesis (LVP), a procedure requiring hospital admissions. As the life expectancy of patients with ESLD and refractory ascites (if ineligible for liver transplantation) is on average ≤ 6 months, frequent hospital visits are inappropriate from a palliative perspective. One alternative is long-term abdominal drains (LTADs), used successfully in patients whose ascites is due to malignancy. Although inserted in hospital, these drains allow ascites management outside of a hospital setting. LTADs have not been formally evaluated in patients with refractory ascites due to ...
Umbilical hernias are common in patients with cirrhosis of the liver and ascites. However, spontaneous rupture of the hernia is not frequently seen. This is a serious complication and carries a high mortality. A search of the literature shows that patients have been managed both operatively and nonoperatively for this condition. We present a case of spontaneous rupture of an umbilical hernia in a patient with cirrhosis and ascites which was managed successfully with hernia repair ...
It has recently been shown that repeated large-volume paracentesis associated with intravenous albumin infusion is a rapid, effective, and safe therapy of ascites in cirrhosis. To investigate whether intravenous albumin infusion is necessary in the treatment of cirrhotics with large-volume paracentesis, 105 patients with tense ascites were randomly allocated into two groups. Fifty-two patients (group 1) were treated with paracentesis (4-6 L/day until disappearance of ascites) plus intravenous albumin infusion (40 g after each tap), and 53 (group 2) with paracentesis without albumin infusion. After disappearance of ascites, patients were discharged from the hospital with diuretics. Patients developing tense ascites during follow-up were treated according to their initial schedule. Paracentesis was effective in eliminating the ascites in 50 patients from group 1 and in 48 from group 2, with the duration of the hospital stay being approximately 11 days in both groups. Paracentesis plus intravenous ...
Define LeVeen shunt. LeVeen shunt synonyms, LeVeen shunt pronunciation, LeVeen shunt translation, English dictionary definition of LeVeen shunt. n. 1. The act or process of turning aside or moving to an alternate course. 2. A railroad switch. 3. Electricity A low-resistance connection between two...
Ovarian cancer ascitic fluid, which contains malignant cells, is usually present in women with an advanced stage disease. There are currently no effective therapies for the treatment of ovarian cancer ascitic fluid. We developed a new therapeutic strategy to target expression of the diphtheria toxin fragment A gene in ovarian tumor cells under the control of H19 regulatory sequences. A 64-year-old Caucasian woman was diagnosed with a stage IIIc epithelial ovarian cancer. She suffered from progressive disease, accumulation of malignant ascites that needed to be drained weekly, abdominal pain, vomiting, anorexia and severe weakness. Infusion of the diphtheria toxin A chain-H19 plasmid into the peritoneum of our patient resulted in complete resolution of the ascites with minimum adverse events. On the basis of this preliminary experience, we are currently conducting an extensive Phase I study on a larger number of patients in order to assess the safety and preliminary efficacy of this novel patient
Spontaneous bacterial peritonitis (SBP) is the development of a bacterial infection in the peritoneum causing peritonitis, despite the absence of an obvious source for the infection. It occurs almost exclusively in people with portal hypertension (increased pressure over the portal vein), usually as a result of cirrhosis of the liver. It can also occur in patients with nephrotic syndrome. The diagnosis of SBP requires paracentesis (aspiration of fluid with a needle) from the abdominal cavity. If the fluid contains bacteria or large numbers of neutrophil granulocytes (>250 cells/µL) (a type of white blood cells), infection is confirmed and antibiotics are required to avoid complications. In addition to antibiotics, infusions of albumin are usually administered. Signs and symptoms of spontaneous bacterial peritonitis include fevers, chills, nausea, vomiting, abdominal tenderness, and general malaise. Affected individuals may complain of abdominal pain and worsening ascites. Thirteen percent of ...
Paracentesis-induced circulatory dysfunction (PICD) is a recently described complication that can be prevented with the administration of plasma expanders. The aim of this study was to compare the efficacy of saline versus albumin in the prevention of PICD. Patients were randomized to receive albumin or saline after total paracentesis. Patients readmitted as a consequence of a second episode of tense ascites were treated with total paracentesis and the alternative plasma expander. After randomization, 35 patients received saline and 37 received albumin. Twenty-one patients were readmitted for tense ascites and treated with the alternative expander. Significant increases in plasma renin activity (PRA) were found 24 hours and 6 days after paracentesis when saline was used (baseline, 5.6 +/- 5.7; 24 hours, 7.6 +/- 6.9; 6 days, 8.5 +/- 8.0 ng. mL(-1). hr(-1); P ,.05 and P ,.01 vs. baseline, respectively), whereas no significant changes were observed with albumin. The incidence of PICD was ...
Ascites is a major complication of cirrhosis. There are several evidence-based articles and guidelines for the management of adults, but few data have been published in relation to children. In the case of a pediatric patient with cirrhotic ascites (PPCA), the following questions are raised: How are the clinical assessment and ancillary tests performed? When is ascites considered refractory? How is it treated? Should fresh plasma and platelets be infused before abdominal paracentesis to prevent bleeding? What are the hospitalization criteria? What are the indicated treatments? What complications can patients develop? When and how should hyponatremia be treated? What are the diagnostic criteria for spontaneous bacterial peritonitis? How is it treated? What is hepatorenal syndrome? How is it treated? When should albumin be infused? When should fluid intake be restricted? The recommendations made here are based on pathophysiology and suggest the preferred approach to diagnostic and therapeutic ...
Learn more about Abdominal Paracentesis at Reston Hospital Center DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
Learn more about Abdominal Paracentesis at Portsmouth Regional Hospital DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
Summerville, K. and Preston, Nancy (2001) Abdominal paracentesis. In: The Royal Marsden Hospital Handbook of Clinical Procedures :. Blackwell Science, Oxford.. Full text not available from this repository ...
Ascites is a major and common complication of liver cirrhosis. Large or refractory ascites frequently necessitates paracentesis. The aim of our study was to investigate the effects of paracentesis on hemodynamic and respiratory parameters in critically ill patients. Observational study comparing hemodynamic and respiratory parameters before and after paracentesis in 50 critically ill patients with advanced hemodynamic monitoring. 28/50 (56%) required mechanical ventilation. Descriptive statistics are presented as mean ± standard deviation for normally distributed data and median, range, and interquartile range (IQR) for non-normally distributed data. Comparisons of hemodynamic and respiratory parameters before and after paracentesis were performed by Wilcoxon signed-rank tests. Bivariate relations were assessed by Spearmans correlation coefficient and univariate regression analyses. Median amount of ascites removed was 5.99 L (IQR, 3.33-7.68 L). There were no statistically significant changes in
CA125 is a well-established ovarian cancer (OC) serum biomarker. The CA125 heavily glycosylated epitope is carried by the MUC16 mucin, a high molecular weight transmembrane mucin. Upon proteolytic cleavage, the extracellular domain of MUC16 is released from the cell surface into malignant ascites and blood vessels. Previous studies have shown that both tumor and surrounding mesothelial cells may express MUC16. Although little is known about the regulation of MUC16 expression in these cells, recent evidence suggest that inflammatory cytokines may stimulate MUC16 expression. Because malignant ascites is a pro-inflammatory environment, we investigated whether OC ascites stimulate the expression and release of MUC16 by human peritoneal mesothelial cells (HPMCs). HPMCs were isolated from peritoneal lavages of women operated for conditions other than cancer. MUC16 protein expression was determined by immunoblot, immunofluorescence or immunohistochemistry depending on the experiments. The release of MUC16 from
In patients with ascites, a low SAAG (serum-ascites albumin gradient) ,1.1 g/dl is usually thought to be caused by non-portal hypertensive etiologies. However, in this cohort of 76 cirrhotic patients withlow SAAG, the etiology could be identified in only 38% (bacterial peritonitis, malignancy, nephrotic syndrome). In non-cirrhotics, the etiology could be identified in 75% of cases. In those cirrhotics who had a repeat paracentesis to determine etiology, 73% had a high SAAG on repeat paracentesis. In patients with cirrhosis, the predictive value of SAAG in determining etiology of ascites is low (abstract).. ...
Large volume paracentesis is an effective treatment for refractory ascites. The need for plasma volume expansion after paracentesis is controversial. Some studies have failed to demonstrate any disturbances in systemic or renal haemodynamics 48 hours after a single 5 litre paracentesis.5 14 However, other studies have highlighted the potential harmful effects on circulatory homeostasis after massive paracentesis in patients with tense ascites when performed without simultaneous plasma volume expansion.1 2 The pathogenesis of PCD remains incompletely understood. Recently, Ruiz del Arbolet al showed that the degree of activation of the renin-angiotensin system and sympathetic nervous system six days after paracentesis correlated inversely with changes in SVR.13 This finding suggests that accentuation of the peripheral arterial vasodilatation of cirrhosis occurs sometime after massive paracentesis. Similar results were observed in a recently published study14 showing that the increase in PRA and ...
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In cirrhosis, the development of ascites and the response to diuretics are determined by the RAAS (renin-angiotensin-aldosterone system) and renal sodium handling system. We hypothesized that SNPs (single nucleotide polymorphisms) affecting candidate genes in the RAAS and renal sodium handling pathway may influence initial diuretic responsiveness and affect clinical outcome in non-azotaemic cirrhotic patients with moderate ascites. We prospectively recruited 176 patients and 245 controls and determined their genetic polymorphisms for 24 SNPs of ten genes involved in the RAAS and renal sodium handling pathway. In cirrhotic patients with moderate ascites, multivariate analysis showed that diuretic unresponsiveness was predicted by a high basal plasma aldosterone level, by a high aldosterone/renin ratio and by specific risk genotypes of ACE (gene encoding angiotensin-converting enzyme), CYP11B2 (gene encoding aldosterone synthase) and ADDA (gene encoding α-adducin). This association between ...
The present study was designed to examine the anatomical parameters of the cardiopulmonary system, the function of venous blood gas parameters and the development of ascites incidence in two genetic line chickens. Three hundred forty day-old chickens from two pure broiler breeder lines, which were different in their growth rate and susceptibility to ascites syndrome were obtained. The relative heart and lung weights, the volumes of the heart, lung and thorax cavity, the incidence of ascites, and the venous blood gas parameters in these two genetic line chickens were followed. In the present study, the incidence of ascites and right ventricular hypertrophy was markedly higher in the fast-growing broiler chickens compared to the slow-growing chickens, as two genetic line chickens exhibited significant differences in their growth performance traits. The volumes of the thorax cavity, before and after removing the heart and lung tissues, were lower in fast-growing broiler chickens compared to the slow
Poultry is key in genetic research due to breeding feasibility, relatively short generation interval, and distinct phenotypes. It is estimated that 8% of broiler deaths annually can be attributed to ascites, an economically important disease that has been challenging the industry for the past 2 decades. Genetically selected ascites resistant (RES) and susceptible (SUS) chicken lines have been established and maintained by the University of Arkansas, Fayetteville. Intensive research efforts have been made to reveal physiological and biochemical characteristics for the incidence of ascites. Since the whole genome of the major ancestral chicken, the Red Jungle Fowl, has been sequenced, genome-wide genetic study is now possible in chickens to identify genetic variations throughout the entire genome. To identify genetic biomarkers responsible for ascites resistance or susceptibility, whole genome sequences of genetically selected chicken lines (RES and SUS) in addition to the unselected parental Relaxed line
Spontaneous bacterial peritonitis (SBP) is an acute bacterial infection of ascitic fluid. Generally, no source of the infecting agent is easily identifiable, but contamination of dialysate can cause the condition among those receiving peritoneal dialysis (PD).
Antibiotic prophylaxis for patients with risk factors for spontaneous bacterial peritonitis (SBP) include: Known history of SBP: Typically prolonged...
Probiotic therapy in conjunction with antimicrobial treatment does not improve efficacy in the treatment of spontaneous bacterial peritonitis, as was found in a double-blind, placebo-controlled, rando... more
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We report successful repair of an aneurysmal aorta-right atrial fistula causing intractable ascites. The clamped "ascending aorta" was drained for mixed return after perfusion through the femoral vessels and opened during hypothermic arrest. Return cannulation through the fistula permitted definitive repair.. ...
Ca2+ uptake into Ehrlich ascites tumor cells was studied at 0°C in the presence of mitochondrial inhibitors, conditions that minimized complications caused by sequestration of Ca2+ into organelles or by excretion. Under these conditions Ruthenium Red inhibited Ca2+ uptake, but other previously implicated ions, such as Pi or Mg2+, had no effect. Valinomycin either inhibited or slightly stimulated Ca2+ uptake depending on the presence of excess K+ on the outside or inside of the cell, respectively. Nigericin inhibited Ca2+ transport. Based on these data we propose an electrogenic uptake of Ca2+, possibly via a Ca2+/H+ antiport mechanism. The observation that glucose inhibited Ca2+ uptake suggested that in Ehrlich ascites tumor cells an energy-driven Ca2+ expulsion mechanism is operative, similar to that in erythrocytes. Plasma membrane preparations of ascites tumor cells were found to contain a Ca2+-dependent ATPase. These preparations, when incorporated into liposomes in an inside-out orientation,
The report also examines the role of shipping in total should play abatement dangerous climate change is widely accepted. Els impotens .increase in the global average temperature of more than 2? C to be above pre-industrial levels. It is clear, a global approach is particularly preferred. Further research further research mentioned in the report identifies an allocation methodology for countries which can be agreed upon by many nation states to, it would be a great help to the development of a global strategy .. Complications clinical guidelines - the European guidelines for the management the ascites, spontaneous bacterial peritonitis and Hepatorenal syndrome cirrhosis of the liver Released.. Estimated that 75 % of patients having ascites Western Europe and U.S. Are cirrhosis of the liver as cause. Development of ascites is an extremely common even debilitating complication to cirrhotic patients and has a huge impact on longevity and life quality. MLP and hepatorenal syndrome be ominously ...
In both diagnostic and large-volume paracentesis, the doctor first numbs the skin with a local anesthetic. He or she then inserts a needle through the abdominal wall, and 1 to 2 inches into the abdomen. In some cases, the doctor may use ultrasound to find the location of the abdominal fluid. You may feel some pressure as the needle is inserted. In diagnostic paracentesis, the doctor only removes a small amount of fluid, which is then sent to a laboratory for tests. In large-volume paracentesis, the doctor drains all, or a portion, of the fluid in the abdomen into a vacuum bottle. In severe cases, the fluid will need to be removed in several sessions, with about a gallon being removed per session. Once the drainage is completed, the needle is removed, and a dressing is applied to the puncture site. This procedure usually takes about 20 to 30 minutes, but may take longer if a large amount of fluid is being removed. ...
There are several complications of Portal Hypertension(PH), including one of the most precarious side effects called Esophageal Varices (covered in a previous post), and of lesser degrees are the conditions of ascites, and splenomegaly. Ascites takes place when excess fluid accumulates between
Your doctor puts a numbing medicine into your belly. Once the area is numb, your doctor will gently and slowly put the paracentesis needle in where the extra fluid is likely to be. If a large amount of fluid is present, the paracentesis needle may be hooked by a small tube to a vacuum bottle for the fluid to drain into it.. Generally, up to 4 L of fluid is taken out. If your doctor needs to remove a larger amount of fluid, you may be given fluids through an intravenous line (IV) in a vein in your arm. It is important that you lie completely still during the procedure, unless you are asked to change positions to help drain the fluid.. When the fluid has drained, the needle is taken out and a bandage is placed over the site. Paracentesis takes about 20 to 30 minutes.. ...
In the study, GI endoscopy assistants performed 1100 large-volume paracenteses in 628 patients. Of these patients 513 had cirrhosis. The team found that the pre-procedure mean international normalized ratio for prothrombin time was 1.7, and the mean platelet count was 50.4 x 103/L. They found that the performance of 3 to 7 supervised paracenteses was required before competence was achieved. The team did not observe any significant procedure-related complications, even in patients with marked thrombocytopenia or prolongation in the prothrombin time. The mean duration of large-volume paracentesis was 97 minutes, and the mean volume of ascitic fluid removed was 8.7 L. Dr Catherine Grabaus team concluded, "Large-volume paracentesis can be performed safely as an outpatient procedure by trained gastrointestinal endoscopy assistants". "Ten supervised paracenteses would be optimal for training the operators carrying out the procedure." "The practice guideline of the American Association for the Study ...
Minghui.org) My name is Zhang Guoyu. Im a 44-year-old farmer from Dezhou City, Shandong Province. In September 2012, I experienced extreme swelling in my legs and stomach. I sought treatment at a local hospital for seven days, but doctors were unable to relieve my condition.. I was then transferred to Dezhou Citys Lingxian Hospital of Traditional Chinese Medicine, where I was diagnosed with hepatitis. The doctors immediately began treatment, but my condition did not improve.. Within two weeks, my stomach swelled to the point that I appeared seven or eight months pregnant. My limbs, however, became emaciated to the point that they were skin and bones.. I was next sent to Dezhou Municipal Hospital, where I was diagnosed with cirrhotic ascites (abdominal fluid buildup). To treat my condition, I was continually infused with an expensive intravenous solution. Unfortunately, my condition only worsened.. Within 10 days, my stomach became so bloated I thought it would explode. Giving up all hope, I ...
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Malignant ascitis (MA) is a highly intractable and immunotherapy-resistant state of advanced gastrointestinal and ovarian cancers. Using a murine model of MA with CT26 colon cancer cells, we here determined that the imbalance between the VEGF-A/vascular permeability factor and its decoy receptor, soluble fms-like tryrosine kinase receptor-1 (sFLT-1), was a major cause of MA resistance to dendritic cell (DC)-based immunotherapy. We found that the ratio of VEGF-A/sFLT-1 was increased not only in murine but also in human MA, and F-gene-deleted recombinant Sendai virus (rSeV/dF)-mediated secretion of human sFLT-1 by DCs augmented not only the activity of DCs themselves, but also dramatically improved the survival of tumor-bearing animals associated with enhanced CTL activity and its infiltration to peritoneal tumors ...
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Doses provided in this table are for patients with normal renal and hepatic function. Click on drug link to go to dosing guidelines. Some antimicrobials are restricted (ID-R). Click on link for guidelines on obtaining authorization.. ...
This procedure may be done in your doctors office, an emergency room, or the X-ray department of a hospital, or at your bedside in the hospital.. If a large amount of fluid is going to be taken out during the procedure, you may lie on your back with your head raised. People who have less fluid taken out may sit up. The site where your doctor will put the needle is cleaned with a special soap and draped with sterile towels.. Your doctor puts a numbing medicine into your belly. Once the area is numb, your doctor will gently and slowly put the paracentesis needle in where the extra fluid is likely to be. Your doctor will be careful to not poke any blood vessels or the intestines. If your test is done in the X-ray department, an ultrasound may be used to show where the fluid is in your belly.. If a large amount of fluid is present, the paracentesis needle may be hooked by a small tube to a vacuum bottle for the fluid to drain into it.. Generally, up to 4 L (1 gal) of fluid is taken out. If your ...
Paracentesis is a procedure in which a needle or catheter is inserted into the peritoneal cavity to obtain ascitic fluid for diagnostic or therapeutic purposes. Ascitic fluid may be used to help determine the etiology of ascites, as well as to evaluate for infection or presence of cancer.
... ,Protein A and Protein G bind specifically to Fc regions of many mammalian immunoglobulins. Protein A and Protein G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants,biological,biology supply,biology supplies,biology product
Background Ascites is the most common complication of cirrhosis. It may lead to the consequence of poor prognosis and the deterioration of quality of life. Asopressin V2 receptor antagonists is a kind...
Learn about ascites, a common problem in patients with cirrhosis, from the Cleveland Clinic. Find causes, symptoms, potential complications and treatments.
Medium-chain triglycerides (MCT)-based diet can be tried as a first option in chylous ascites treatment. In resistant or unresponsive cases, somatostatin along with TPN can have use in closing the lymphatic leakage or relieving the symptoms effectively and rapidly. Conventional regimens including en …
List of 461 causes for Ascites and Kidney failure, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
Going through lupus flare up can either be constant joint pain, exhaustion or for me failing kidneys, edema and ascites. I was in the hospital for about a month because my flare up was that bad. I told the doctors that this is probably my longest flare up as it started late January-February but after…
ascites). Treatment[edit]. Bloating is not life-threatening. In most cases, bloating can be handled with simple home remedies ...
Ascites. *Clubbing (deformed nails). *Cough. *Death rattle (last moments of life in a person/animal) ...
Malignant ascites. *Malignant transformation. Non-oncologic disorders referred to as "malignant": *Malignant hypertension ...
Marked recent weight loss is a major clinical manifestation, and unresponsiveness of the ascites to diuretics is an additional ... Kaman L, Behera A, Singh R, Katariya RN (2001). "Internal pancreatic fistulas with pancreatic ascites and pancreatic pleural ... Bibliography Brooks JR (1983). "Pancreatic ascites". In Brooks JR. Surgery of the Pancreas (1st ed.). Philadelphia: WB Saunders ... Smith EB (1953). "Hemorrhagic ascites and hemothorax associated with benign pancreatic disease". AMA Arch Surg. 67 (1): 52-6. ...
People who have ascites. *Previous radiation therapy to the pelvis. *A complex hernia ...
腹水(Ascites)是指腹腔內有液體積聚,超過正常量的症狀。腹水最常見的病因是肝硬化和其他嚴重的肝臟疾病,但它的出現也可以是其他重大疾病的徵象,如肝癌末期。腹水病因的診斷一般是通過血液檢驗、腹部的超聲波檢查、腹腔穿刺術(英語:paracentesis) ... The serum-ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of
ascites) Bloating is not life-threatening. In most cases, bloating can be handled with simple home remedies and changes in ... Abdominal distension (or "distended abdomen") can be a sign of many other conditions, including: Ascites Capillaria ...
Liver damage (cirrhosis). Liver damage can cause fluid to back up in the abdomen (ascites) and the legs.[8] ... "Ascites". Medline Plus. National Institutes of Health. Retrieved 2015-01-03 ...
AscitesEdit. When fluid collects in the abdominal cavity, this condition is called ascites. This is usually not noticeable ... Chylous ascites heals best if the lymphatic vessel involved is closed. Heart failure can cause recurring ascites.[1] ...
It usually presents with omental metastases which cause ascites. Papillary serous cystadenocarcinoma "Female Genital Pathology ...
If there is ascites, diagnostic paracentesis (removal of a fluid sample with a needle) may be required to identify spontaneous ... These may include jaundice (yellow discolouration of the skin and the whites of the eyes), ascites (fluid accumulation in the ... Saab S, Nieto JM, Lewis SK, Runyon BA (2006). "TIPS versus paracentesis for cirrhotic patients with refractory ascites". ... This is used in the treatment of refractory ascites, bleeding from oesophageal varices and hepatorenal syndrome.[8][9] TIPS- ...
I. Uridine-cytidine kinase of Novikoff ascites rat tumor". The Journal of Biological Chemistry. 244 (8): 2204-9. PMID 5782006. ... Skold O (1960). "Uridine kinase from Erlich ascites tumor: purification and properties". J. Biol. Chem. 235: 3273-3279.. ...
Distended - hepatomegaly with fatty liver, ascites may be present. Cardiovascular. Bradycardia, hypotension, reduced cardiac ...
In the advanced stages it also extends to the pleural cavity and peritoneum (ascites) and can even develop into a generalized ... Spontaneous bacterial peritonitis can develop where there is ascites present. This is a frequent development in children but ... Dyspnea may be present due to pleural effusion or due to diaphragmatic compression with ascites. ...
Pere Ginés; Vicente Arroyo; Juan Rodés; Robert W. Schrier (15 April 2008). Ascites and Renal Dysfunction in Liver Disease: ...
Owing to portal obstruction, ascites occurs, followed later by generalised oedema. The stools are light or clay-colored, and ...
In addition to change in shape being a possible side effect from ascites and umbilical hernias, the navel can be involved in ... "Ascites". The Merck Manuals.. *^ Bagade, Pallavi V; Guirguis, Mamdouh M (2009). "Menstruating from the umbilicus as a rare ... unexpected change in shape may be the result of ascites.[11] ...
Cardenas, Andres; Chopra, Sanjiv (2002). "Chylous ascites". The American Journal of Gastroenterology. 97 (8): 1896-900. doi: ...
These signs include ascites, pleural effusion, and edema of the limbs and trunk. Weight loss is seen with long-term disease. ...
Nwokolo, C. (1967). Ascites in Africa. London: British Medical Journal. Nwokolo, Chukwuedu. (1969). Biafran Refugees: Problems ... doi:10.1136/bmj.2.5263.1357-a. PMC 1970434 . "Ascites in Africa". British Medical Journal. Retrieved 1 June 2014. "Biafran ...
1996). "Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites ... ascites). The spectrum continues with diuretic-resistant ascites, where the kidneys are unable to excrete sufficient sodium to ... and the presence of ascites. Specifically, the production of ascites that is resistant to the use of diuretic medications is ... This is believed to be a key step in the pathogenesis of ascites in cirrhotics as well. It has been hypothesized that the ...
Proteomic analysis of microvesicles derived from human colorectal cancer ascites.. Proteomics. 2011-07, 11 (13): 2745-51 [2020- ...
In severe cases, fluid can shift into the peritoneal cavity (abdomen) and cause ascites. As a result of the excess fluid, ...
"Further evidence favoring the concept of the stem cell in ascites tumors of rats". Ann. N. Y. Acad. Sci. 63 (5): 818-30. doi ...
Ascites may be present. The most characteristic feature are elevated levels of gamma glutamyl transferase (100-300 IU/L), ...
Effect of compound on Ehrlich ascites carcinoma growth in CF1 mice at a dose ((20 mg/kg)/day) ip survival at day 9 packed cell ...
Prabhakaran, K.,Patankar, Jahoorahmad M.V.,Neo, Grace T.H. (2004). Chylous ascites following liver resection - Case report. ...
coding on thirty tools of download ascites hyponatremia and hepatorenal syndrome progress in, she Introduces number cells to ... Julia Ross download ascites hyponatremia and hepatorenal syndrome installer is a other co-housing for your mac. ... While this download ascites can calm you a mobile vaccine over website, and some methods and deeds of minutes to know with your ... Download Ascites Hyponatremia And Hepatorenal Syndrome Progress In Treatment. Yarn of the Month. UK-led HARMONI download ...
Ascites is the build-up of fluid in the space between the lining of the abdomen and abdominal organs. ... ascites; Liver failure - ascites; Alcohol use - ascites; End-stage liver disease - ascites; ESLD - ascites ... If you have ascites, call your health care provider right away if you have:. *Fever above 100.5°F (38.05°C), or a fever that ... Ascites results from high pressure in the blood vessels of the liver (portal hypertension) and low levels of a protein called ...
Mild ascites is hard to notice, but severe ascites leads to abdominal distension. Patients with ascites generally will complain ... Those with ascites due to cancer (peritoneal carcinomatosis) may complain of chronic fatigue or weight loss. Those with ascites ... Most experts recommend a diagnostic paracentesis be performed if the ascites is new or if the patient with ascites is being ... "The Management of Ascites in Cirrhosis: Report on the Consensus Conference of the International Ascites Club". Hepatology. 38: ...
The most common causes of ascites are cirrhosis of the liver, heart failure, tumours of the peritoneal membranes, and escape of ... Ascites, accumulation of fluid in the peritoneal cavity, between the membrane lining the abdominal wall and the membrane ... digestive system disease: Ascites. The accumulation of fluid in the abdominal cavity, or ascites, is related to portal ... More About Ascites. 2 references found in Britannica articles. Assorted References. *complication of liver disease* In ...
Find out more about ascites and its causes. ... Ascites happens when fluid accumulates in the abdomen, ... What is ascites?. Ascites occurs when fluid accumulates in the abdomen. This buildup occurs between two membrane layers that ... Prognosis and outlook of ascites depend on the underlying condition.. *Assessment of the progress of ascites may be made by ... Fast facts about ascites. *Ascites is a symptom of another underlying cause. ...
Tapping ascites (2).. Br Med J 1980; 281 doi: https://doi.org/10.1136/bmj.281.6239.550 (Published 23 August 1980) Cite this as ...
The formation of ascites in cirrhosis depends on the presence of unfavorable Starling forces within the hepatic sinusoid and on ... encoded search term (How do ascites form in cirrhosis?) and How do ascites form in cirrhosis? What to Read Next on Medscape. ... The serum-ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of ascites. Ann ... Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club. ...
In transudative ascites, fluid was said to cross the liver capsule because of an imbalance in Starling forces. In general, asci ... ascites was classified as being a transudate or an exudate. ... In general, ascites protein would be less than 2.5 g/dL in this ... In the past, ascites was classified as being a transudate or an exudate. In transudative ascites, fluid was said to cross the ... The serum-ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of ascites. Ann ...
Common causes of ascites are liver disease or cirrhosis, cancers,and heart failure. Signs and symptoms of ascities include ... Ascities treatment guidelines depend upon the condition causing ascites. The prognosis the life expectancy depends on the cause ... Ascites is accumulation of fluid in the abdominal cavity. ... Can ascites be prevented?. *Ascites Symptoms, Causes, Diagnosis ... What are the complications of ascites?. *What is the outlook for ascites? What is the life expectancy of ascites? Can ascites ...
ascites diet mikeray where can i find more detailed info on low sodium/low potasium diets to work with diruetics...end stage ... ascites diet. where can i find more detailed info on low sodium/low potasium diets to work with diruetics...end stage liver ... This discussion is related to http://www.medhelp.org/posts/show/232433>Ascites.. ...
Learn about causes and symptoms and managing ascites. ... Ascites is an abnormal buildup of fluid in the abdomen and can ... When ascites is due to cancer, or if the fluid in the abdomen contains cancer cells, it is often called malignant ascites or ... Ascites. Ascites is an abnormal buildup of fluid in the abdomen, specifically the peritoneal cavity. It occurs when the body ... Managing ascites. Once the cause of ascites is known, your healthcare team can suggest ways to manage it. In some cases, ...
... Kourosh Alavi. ,1 Pradeep R. Atla. ,1 Tahmina Haq. ,1 and Muhammad Y. ... His ascites has completely resolved and he has started to gain weight with improved weight of 120 pounds at 3 months after ... Eosinophilic ascites (EA) is generally a rare finding in clinical practice. When present, it is most commonly associated with ... Ascitic fluid exam was remarkable for low serum-ascites albumin gradient (SAAG), PMN count ,250/mm3, and eosinophils of 62%. ...
Eli Lilly and Company has received its fourth U.S. Food and Drug Administration approval for CYRAMZA (ramucirumab). CYRAMZA (ramucirumab injection 10 mg/mL solution) is now also indicated in combination with FOLFIRI (irinotecan, folinic acid, and 5-fluorouracil) chemotherapy for the treatment of patients with metastatic colorectal cancer (mCRC) with disease progression on or after prior therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine.. ...
... it is known as ascites. Ascites usually occurs when the liver stops working properly. Fluid fills the space between the lining ... People with cirrhotic ascites have a two-year... ... Ascites Causes and Risk Factors. Ascites is most often caused ... People with cirrhotic ascites have a two-year... Read More. When fluid builds up inside the abdomen, it is known as ascites. ... Symptoms of Ascites. Symptoms of ascites can appear either slowly or suddenly, depending on the cause of the fluid buildup. ...
This Ascites page on EmpowHER Womens Health works best with javascript enabled in your browser.. Toggle navigation Womens ... Im sure the doctor already explained what ascites is, but I can provide a resource for you as well. ...
Ascites has many causes, most of which can be very serious. In cats, ascites is caused by the leakage of fluid into the abdomen ... Overview of Ascites in Cats. Ascites is the abnormal accumulation of fluid in the abdominal cavity. The volume of the fluid can ... Any amount of ascites is a significant finding, however, and steps should be taken to find a diagnosis. Ascites has many ... Causes of Ascites in Cats. Hypoalbuminemia Causes of Ascites in Cats. Hypoalbuminemia is a decrease in serum albumin levels. ...
In dogs, ascites has many causes, most of which can be very serious. Ascites is caused by the leakage of fluid into the abdomen ... Overview of Ascites in Dogs. Ascites is the abnormal accumulation of fluid in the abdominal cavity. The volume of the fluid can ... Any amount of ascites is a significant finding, however, and steps should be taken to find a diagnosis. Ascites has many ... Ascites, itself, usually does not cause a problem, but the primary disease process causing the ascites can be a serious ...
Patients with massive ascites may experience abdominal discomfort, depressed appetite, and decreased oral intake. Diaphragmatic ... The serum-ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of ascites. Ann ... Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club. ... Ascites and spontaneous bacterial peritonitis. Schiff ER, Sorrell MF, Maddrey WC, eds. Schiffs Diseases of the Liver. 8th ed. ...
This CT scan of the lower abdomen shows a massive amount of free abdominal fluid (ascites) in a patient with ovarian cancer. ... ascites) in a patient with ovarian cancer. ...
The term ascites is of Greek origin, from the word askos, which means ... Definition Ascites is defined as an abnormal amount of intraperitoneal fluid. ... Biliary ascites. Biliary ascites in neonates is rare. The usual clinical presentation is that of ascites with mild jaundice ( ... Urinary ascites. Antenatal diagnosis of urinary ascites has been made with fetal US. Signs and symptoms of urinary ascites ...
Compare risks and benefits of common medications used for Ascites. Find the most popular drugs, view ratings, user reviews, and ... Learn more about Ascites. IBM Watson Micromedex. *Ascites. ICD-10 CM Clinical Codes (External). *Look up ICD10 codes for ... About Ascites: An excess of fluid in the peritoneal cavity (membrane lining of the abdomen). This is typically caused by liver ... Drugs Used to Treat Ascites. The following list of medications are in some way related to, or used in the treatment of this ...
... transplant-free survival when compared to large volume paracentesis in patients with cirrhosis and difficult to treat ascites. ... Tags: Ascites, Bleeding, Blood, Blood Vessels, Cirrhosis, Heart, Hernia, Life Expectancy, Ligation, Liver, Liver Disease, ... Ascites is the build up of fluid in the abdomen and variceal bleeding involves the rupture of veins in the gastrointestinal ... The Gore study for ascites patients comes on the heels of a landmark study published in The New England Journal of Medicine ...
Currently have ascites even with TIPS. It used to be under control but even TIPS is not controlling it any more. The volume of ... Ascites- lab values. akoger05akog Currently have ascites even with TIPS. It used to be under control but even TIPS is not ... Ascites- lab values. Currently have ascites even with TIPS. It used to be under control but even TIPS is not controlling it any ... My question is, are there any specific lab values that represent ascites and if the "causes" of ascites specifically are ...
  • D. E. Brennemann, L. McGee and A. A. Spector, Cholesterol metabolism in the Ehrlich ascites tumor, Cancer Res. (springer.com)
  • Reinaldo J. da Silva, Márcia G. da Silva, Lízia C. Vilela, and Denise Fecchio, "Cytokine profile of Ehrlich ascites tumor treated with Bothrops jararaca venom," Mediators of Inflammation , vol. 11, no. 4, pp. 197-201, 2002. (hindawi.com)
  • We previously demonstrated that Bothrops jararaca venom ( Bj V) has an antitumor effect on Ehrlich ascites tumor (EAT) cells and induces an increase of polymorphonuclear leukocytes in early stages of tumor growth. (hindawi.com)
  • Ehrlich-Lettre ascites carcinoma (EAC) is also known as Ehrlich cell. (wikipedia.org)
  • The sterol ester fraction of Ehrlich ascites cell lipids was analyzed to determine: the type of sterol, the identity of the fatty acids esterified to the sterol, the presence or absence of carcinolipin, and the presence or absence of O -alkyl cholesteryl ethers. (aacrjournals.org)
  • An alpha-D-galactosyltransferase activity in Ehrlich ascites tumor cells. (wikipedia.org)
  • Research is being conducted with Ehrlich ascites tumor cells in vitro to see if phosphoethanolamine could be used in cancer treatment. (wikipedia.org)
  • Micronucleus induction by a chemical was first reported in Ehrlich ascites tumor cells treated with colchicine. (wikipedia.org)
  • Diseases that can cause severe liver damage can lead to ascites. (medlineplus.gov)
  • Cancer and infections may lead to ascites because of the increased fluid production in the peritoneal cavity exceeding resorptive capacity. (clinicaladvisor.com)
  • Hypoalbuminemia, with resultant decrease in oncotic pressure, may lead to ascites in protein-losing enteropathy, malnutrition, and nephrotic syndrome. (clinicaladvisor.com)
  • However, their hypothetical appearance in the cirrhotic patient is considered pathological since ultimately they lead to ascites development. (hindawi.com)
  • If the physical examination is equivocal, ultrasound confirms the diagnosis of Ascites. (hpathy.com)
  • The present study was to create and evaluate a new bioscore combined with PCT, sNFI and dCHC in the diagnosis of ascites infection in cirrhotic patients. (springer.com)
  • A bioscore of ≥3.40 was considered to be statistically significant in making a positive diagnosis of ascites infection. (springer.com)
  • Describe the advantages and disadvantages of this technique for diagnosis of Ascites. (endocrinologyadvisor.com)
  • V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of Ascites. (endocrinologyadvisor.com)
  • The diagnosis of ascites includes physical examination along with a detailed medical history so as to identify the possible underlying causes, since ascites is often considered a nonspecific symptom for other diseases. (planetayurveda.com)
  • Despite being a rare cause of ascites, with approximately one hundred cases reported worldwide, PMP must be considered in the differential diagnosis of ascites, particularly if gelatinous. (elsevier.es)
  • Those with ascites due to cancer (peritoneal carcinomatosis) may complain of chronic fatigue or weight loss. (wikipedia.org)
  • However, ascites is more often associated with liver disease and other long-lasting (chronic) conditions. (thefreedictionary.com)
  • Chronic pancreatitis can result in malnutrition, leading to decreased total body protein, loss of oncotic pressure, and ascites. (emedicinehealth.com)
  • Development of ascites associated with chronic hepatitis C suggests a 5-year survival time (Saadeh & Davis, 2004). (thefreelibrary.com)
  • Ascites tends to occur in long-standing (chronic) rather than in short-lived (acute) liver disorders. (merckmanuals.com)
  • On examination, a voluminous ascites was noted, with no signs of chronic liver disease. (elsevier.es)
  • This book addresses the increasing incidence and significance of diseases, such as ascites, renal dysfunction, cirrhosis and hypertension where both organs are involved. (ecampus.com)
  • Soft and stable" handling of parenchymal organs could be achieved using "bellows" type suckers in combination with artificial ascites. (sages.org)
  • Other signs of ascites may be present due to its underlying cause. (wikipedia.org)
  • In the infant or child, the signs of ascites include shifting dullness to percussion, a fluid wave, and abdominal distention. (medscape.com)
  • Another potential emergency situation is the rapid onset of ascites. (petplace.com)
  • Any amount of ascites is a significant finding, however, and steps should be taken to find a diagnosis. (petplace.com)
  • Other factors that may contribute to ascites are salt and water retention. (medicinenet.com)
  • Many underlying diseases can be responsible for causing ascites, including tuberculosis , kidney disease, pancreatitis , and an underactive thyroid. (medicalnewstoday.com)
  • Ascites may also result from other systemic diseases, such as heart failure (cardiac Ascites) and nephritic syndrome, or from primary peritoneal pathology, such as peritoneal carcinomatosis or tuberculosis. (hpathy.com)
  • P. plecoglossicida is a fish pathogenic species, causing hemorrhagic ascites in the ayu (Plecoglossus altivelis). (wikipedia.org)
  • Monoclonal antibody (mAb) ascites fluid production in mice is a well described method of antibody production, although ethical questions regarding the pain and distress of the animals utilized in this process have been raised. (hindawi.com)
  • Monoclonal antibody (mAb) ascites fluid production in mice is a well described method of antibody production [ 1 - 3 ]. (hindawi.com)