Arthritis infectious. Medical search

A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.

Arthritis caused by BACTERIA; RICKETTSIA; MYCOPLASMA; VIRUSES; FUNGI; or PARASITES.

Arthritis of children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.

A type of inflammatory arthritis associated with PSORIASIS, often involving the axial joints and the peripheral terminal interphalangeal joints. It is characterized by the presence of HLA-B27-associated SPONDYLARTHROPATHY, and the absence of rheumatoid factor.

An aseptic, inflammatory arthritis developing secondary to a primary extra-articular infection, most typically of the GASTROINTESTINAL TRACT or UROGENITAL SYSTEM. The initiating trigger pathogens are usually SHIGELLA; SALMONELLA; YERSINIA; CAMPYLOBACTER; or CHLAMYDIA TRACHOMATIS. Reactive arthritis is strongly associated with HLA-B27 ANTIGEN.

The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.

Also known as articulations, these are points of connection between the ends of certain separate bones, or where the borders of other bones are juxtaposed.

The clear, viscous fluid secreted by the SYNOVIAL MEMBRANE. It contains mucin, albumin, fat, and mineral salts and serves to lubricate joints.

Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The initial attacks are usually monoarticular but later attacks are often polyarticular.

Antibodies found in adult RHEUMATOID ARTHRITIS patients that are directed against GAMMA-CHAIN IMMUNOGLOBULINS.

Inflammation of a synovial membrane. It is usually painful, particularly on motion, and is characterized by a fluctuating swelling due to effusion within a synovial sac. (Dorland, 27th ed)

A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

A fibrillar collagen found predominantly in CARTILAGE and vitreous humor. It consists of three identical alpha1(II) chains.

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.

Measurement of rate of settling of erythrocytes in anticoagulated blood.

Methods of delivering drugs into a joint space.

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.

The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.

Roentgenography of a joint, usually after injection of either positive or negative contrast medium.

A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis.

A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.

The articulation between a metacarpal bone and a phalanx.

A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.

A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)

Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).

Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.

Antibodies produced by a single clone of cells.

A variable mixture of the mono- and disodium salts of gold thiomalic acid used mainly for its anti-inflammatory action in the treatment of rheumatoid arthritis. It is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis.

The joint that is formed by the distal end of the RADIUS, the articular disc of the distal radioulnar joint, and the proximal row of CARPAL BONES; (SCAPHOID BONE; LUNATE BONE; triquetral bone).

Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.

A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).

A subtype of HLA-DRB beta chains that includes over one hundred allele variants. The HLA-DRB1 subtype is associated with several of the HLA-DR SEROLOGICAL SUBTYPES.

The articulation between the head of one phalanx and the base of the one distal to it, in each finger.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

The articulations between the various TARSAL BONES. This does not include the ANKLE JOINT which consists of the articulations between the TIBIA; FIBULA; and TALUS.

An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.

Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells.

An HLA-DR antigen which is associated with HLA-DRB1 CHAINS encoded by DRB1*04 alleles.

Substances that reduce or suppress INFLAMMATION.

A subclass of HLA-D antigens that consist of alpha and beta chains. The inheritance of HLA-DR antigens differs from that of the HLA-DQ ANTIGENS and HLA-DP ANTIGENS.

Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.

Heterogeneous group of arthritic diseases sharing clinical and radiologic features. They are associated with the HLA-B27 ANTIGEN and some with a triggering infection. Most involve the axial joints in the SPINE, particularly the SACROILIAC JOINT, but can also involve asymmetric peripheral joints. Subsets include ANKYLOSING SPONDYLITIS; REACTIVE ARTHRITIS; PSORIATIC ARTHRITIS; and others.

The articulations extending from the ANKLE distally to the TOES. These include the ANKLE JOINT; TARSAL JOINTS; METATARSOPHALANGEAL JOINT; and TOE JOINT.

A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

A protective layer of firm, flexible cartilage over the articulating ends of bones. It provides a smooth surface for joint movement, protecting the ends of long bones from wear at points of contact.

The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS.

A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

A proinflammatory cytokine produced primarily by T-LYMPHOCYTES or their precursors. Several subtypes of interleukin-17 have been identified, each of which is a product of a unique gene.

Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.

The region in the hindlimb of a quadruped, corresponding to the human ANKLE.

An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*27 allele family.

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

Organic compounds that contain GOLD as an integral part of the molecule. Some are used as ANTIRHEUMATIC AGENTS. The term chrysotherapy derives from an ancient Greek term for gold.

Therapy with two or more separate preparations given for a combined effect.

The articulations extending from the WRIST distally to the FINGERS. These include the WRIST JOINT; CARPAL JOINTS; METACARPOPHALANGEAL JOINT; and FINGER JOINT.

An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.

Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)

A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.

A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.

Component of the NATIONAL INSTITUTES OF HEALTH. It supports research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress. It was established in 1986.

Elements of limited time intervals, contributing to particular results or situations.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.

Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.

3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.

A specific species of bacteria, part of the BORRELIA BURGDORFERI GROUP, whose common name is Lyme disease spirochete.

A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.

Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)

Infections with bacteria of the genus YERSINIA.

Pain in the joint.

Inflammation of the joints of the SPINE, the intervertebral articulations.

Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by AUTOIMMUNE DISEASES.

Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.

The articulation between the head of one phalanx and the base of the one distal to it, in each toe.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.

A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.

Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.

The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.

A plasma protein that circulates in increased amounts during inflammation and after tissue damage.

Deformities of the hand, or a part of the hand, acquired after birth as the result of injury or disease.

Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.

Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.

Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.

Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.

Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.

Bone loss due to osteoclastic activity.

An extracellular endopeptidase of vertebrate tissues similar to MATRIX METALLOPROTEINASE 1. It digests PROTEOGLYCAN; FIBRONECTIN; COLLAGEN types III, IV, V, and IX, and activates procollagenase. (Enzyme Nomenclature, 1992)

An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

A rare complication of rheumatoid arthritis with autoimmune NEUTROPENIA; and SPLENOMEGALY.

The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.

The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.

Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

A double gliding joint formed by the CLAVICLE, superior and lateral parts of the manubrium sterni at the clavicular notch, and the cartilage of the first rib.

The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).

The articulation between a metatarsal bone (METATARSAL BONES) and a phalanx.

An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact mechanism of action is unknown, but it is believed to act via immunological mechanisms and alteration of lysosomal enzyme activity. Its efficacy is slightly less than that of injected gold salts, but it is better tolerated, and side effects which occur are potentially less serious.

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.

Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.

The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.

Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.

Inflammation of the bone.

A species of LENTIVIRUS, subgenus ovine-caprine lentiviruses (LENTIVIRUSES, OVINE-CAPRINE), closely related to VISNA-MAEDI VIRUS and causing acute encephalomyelitis; chronic arthritis; PNEUMONIA; MASTITIS; and GLOMERULONEPHRITIS in goats. It is transmitted mainly in the colostrum and milk.

Treatment of diseases with biological materials or biological response modifiers, such as the use of GENES; CELLS; TISSUES; organs; SERUM; VACCINES; and humoral agents.

Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.

A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)

A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.

The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.

Sites on an antigen that interact with specific antibodies.

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.

Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.

Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.

The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Methods to determine in patients the nature of a disease or disorder at its early stage of progression. Generally, early diagnosis improves PROGNOSIS and TREATMENT OUTCOME.

Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Subset of helper-effector T-lymphocytes which synthesize and secrete IL-17, IL-17F, and IL-22. These cytokines are involved in host defenses and tissue inflammation in autoimmune diseases.

The performance of the basic activities of self care, such as dressing, ambulation, or eating.

A thioglucose derivative used as an antirheumatic and experimentally to produce obesity in animals.

Diseases of BONES.

A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases.

Gram-negative helical bacteria, in the genus BORRELIA, that are the etiologic agents of LYME DISEASE. The group comprises many specific species including Borrelia afzelii, Borellia garinii, and BORRELIA BURGDORFERI proper. These spirochetes are generally transmitted by several species of ixodid ticks.

Glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.

Glycoproteins which have a very high polysaccharide content.

An encapsulated lymphatic organ through which venous blood filters.

The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed)

The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.

Partial or total replacement of a joint.

A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.

Biologically active substances whose activities affect or play a role in the functioning of the immune system.

Combinations of diagnostic or therapeutic substances linked with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; or ANTIGENS. Often the diagnostic or therapeutic substance is a radionuclide. These conjugates are useful tools for specific targeting of DRUGS and RADIOISOTOPES in the CHEMOTHERAPY and RADIOIMMUNOTHERAPY of certain cancers.

Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)

Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.

Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.

In horses, cattle, and other quadrupeds, the joint between the femur and the tibia, corresponding to the human knee.

Surgical reconstruction of a joint to relieve pain or restore motion.

Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

Tuberculosis of the bones or joints.

A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.

The relationship between the dose of an administered drug and the response of the organism to the drug.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Distortion or disfigurement of the foot, or a part of the foot, acquired through disease or injury after birth.

The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.

A hinge joint connecting the FOREARM to the ARM.

A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.

The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.

Specific molecular sites on the surface of various cells, including B-lymphocytes and macrophages, that combine with IMMUNOGLOBULIN Gs. Three subclasses exist: Fc gamma RI (the CD64 antigen, a low affinity receptor), Fc gamma RII (the CD32 antigen, a high affinity receptor), and Fc gamma RIII (the CD16 antigen, a low affinity receptor).

Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)

The joint involving the CERVICAL ATLAS and axis bones.

PROTEOGLYCANS-associated proteins that are major components of EXTRACELLULAR MATRIX of various tissues including CARTILAGE; and INTERVERTEBRAL DISC structures. They bind COLLAGEN fibers and contain protein domains that enable oligomer formation and interaction with other extracellular matrix proteins such as CARTILAGE OLIGOMERIC MATRIX PROTEIN.

The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.

A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.

Antibodies which react with the individual structural determinants (idiotopes) on the variable region of other antibodies.

The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.

A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.

Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

Endoscopic examination, therapy and surgery of the joint.

Presence of calcium salts, especially calcium pyrophosphate, in the cartilaginous structures of one or more joints. When accompanied by attacks of goutlike symptoms, it is called pseudogout. (Dorland, 27th ed)

A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components.

A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.

Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules.

The immovable joint formed by the lateral surfaces of the SACRUM and ILIUM.

The CARPAL BONES; METACARPAL BONES; and FINGER PHALANGES. In each hand there are eight carpal bones, five metacarpal bones, and 14 phalanges.

A class of compounds composed of repeating 5-carbon units of HEMITERPENES.

Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They form into aggregates that provide tissues with the capacity to resist high compressive and tensile forces.

The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.

A fluid-filled sac lined with SYNOVIAL MEMBRANE that provides a cushion between bones, tendons and/or muscles around a joint.

Disease having a short and relatively severe course.

Alpha-toxin and gamma-toxin jointly promote Staphylococcus aureus virulence in murine septic arthritis. (1/959)

Septic arthritis is a common and feared complication of staphylococcal infections. Staphylococcus aureus produces a number of potential virulence factors including certain adhesins and enterotoxins. In this study we have assessed the roles of cytolytic toxins in the development of septic arthritis by inoculating mice with S. aureus wild-type strain 8325-4 or isogenic mutants differing in the expression of alpha-, beta-, and gamma-toxin production patterns. Mice inoculated with either an alpha- or beta-toxin mutant showed degrees of inflammation, joint damage, and weight decrease similar to wild-type-inoculated mice. In contrast, mice inoculated with either double (alpha- and gamma-toxin-deficient)- or triple (alpha-, beta-, and gamma-toxin-deficient)-mutant S. aureus strains showed lower frequency and severity of arthritis, measured both clinically and histologically, than mice inoculated with the wild-type strain. We conclude that simultaneous production of alpha- and gamma-toxin is a virulence factor in S. aureus arthritis. (+info)

Genetic control of experimental lyme arthritis in the absence of specific immunity. (2/959)

Host genetics play an important role in determining resistance or susceptibility to experimental Lyme arthritis. While specific immunity appears to regulate disease resolution, innate immunity appears to regulate disease severity. Intradermal infection with Borrelia burgdorferi yields severe arthritis in C3H/He (C3H) mice but only minimal arthritis in BALB/c mice. Intradermal infection of immunodeficient C3H SCID mice also results in severe arthritis, but arthritis of only moderate severity in BALB/c SCID mice. In the present study, we examined immunodeficient recombinase-activating gene-knockout (RAG-1(-/-)) (RAG-) mice from resistant C57BL/6 (B6) and DBA/2 (DBA) mouse strains. B. burgdorferi-infected B6 RAG- and DBA RAG- mice had little or no ankle swelling, a low occurrence of inflammatory infiltrates in tibiotarsal joints, and low arthritis severity scores in comparison to RAG+ and RAG- BALB/c or C3H mice. Few differences in spirochete DNA levels in ankles of resistant and susceptible RAG- mice were seen. These data suggest that resistance to arthritis development following B. burgdorferi infection is not necessarily dependent on an acquired immune response and can occur despite the presence of high spirochete burden. Thus, genes expressed outside the specific immune response can be central regulators of experimental arthritis. (+info)

Osteonecrosis of the hip in sickle-cell disease associated with tuberculous arthritis. A review of 15 cases. (3/959)

We report a study of 15 cases of tuberculous hips with sickle-cell disease who presented during 1991-1993. Although the osteonecrosis was long-standing, biopsy was nearly always required to reveal the more recent tuberculous infection. Management consisted of 6 months of anti-tuberculous chemotherapy with appropriate palliative surgery 5-8 weeks after the start of drug treatment. The operative techniques which we used are described. The results were good both post-operatively, and in 12 patients followed-up at an average of 3 years. We recommend this combined management for the treatment of secondary tuberculous infections of hips previously damaged by sickle-cell disease. (+info)

Longitudinal and cross-sectional variability in markers of joint metabolism in patients with knee pain and articular cartilage abnormalities. (4/959)

OBJECTIVE: To determine the within- and between-patient variability in the concentrations of synovial fluid, serum and urine markers of joint tissue metabolism in a cohort of patients with knee pain and cartilage changes consistent with early-stage knee osteoarthritis. DESIGN: Samples of synovial fluid, serum, and urine were obtained from 52 patients on eight different occasions during 1 year, as part of a clinical trial in patients with cartilage abnormalities and knee pain. In joint fluid, aggrecan fragments were quantified by dye precipitation and enzyme-linked immunosorbent assay (ELISA), and matrix metalloproteinases-1 and -3, and tissue inhibitor of metalloproteinases-1 by sandwich ELISAs. In serum, keratan sulfate was quantified by ELISA. Type I collagen N-telopeptide cross-links in urine were determined by ELISA. RESULTS: The degree of cross-sectional variability in marker concentrations did not vary between the different sampling occasions, and did not differ between the periods of weeks 0 (baseline), 1-4 (treatment) and 13-26 (follow-up). Both between-patient and within-patient coefficients of variation varied for markers in different body fluid compartments, with the lowest variability for serum keratan sulfate, followed by urine type I collagen N-telopeptide crosslinks, and the highest for synovial fluid markers. For synovial fluid, aggrecan fragments showed the least variability, and matrix metalloproteinases the highest. One patient with septic arthritis showed a fivefold peak increase in joint fluid aggrecan fragment concentrations, while the concentration of matrix metalloproteinase-3 increased 100-fold. CONCLUSIONS: Molecular markers of joint tissue metabolism have been suggested as, for example, outcome measures for clinical trials of disease-modifying drugs in osteoarthritis. This report is the first to present data on between- and within-patient variability for such molecular markers in three different body fluid compartments in stable cohort of patients. The availability of such data enables calculations to determine the number of patients needed in prospective studies using these markers as outcome measures. (+info)

IL-1beta, IL-6 and TNF-alpha in synovial fluid of patients with non-gonococcal septic arthritis. (5/959)

Interleukin-1 beta (IL-1beta), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are the main proinflammatory cytokines responsible for the inflammatory process and cartilage destruction of inflammatory arthropathies. The present study sequentially measured the concentrations of these cytokines and their proportions of detectable levels in the synovial fluid (SF) of 23 patients with non-gonococcal (GC) septic arthritis before and after treatment. Persistently high concentrations and proportions of IL-6 and TNF-alpha were found up to day 7 of treatment, while SF IL-1beta concentration declined significantly after day 7 (p = 0.036). SF IL-1beta and TNF-alpha correlated with each other significantly and with SF WBC counts (p < 0.01). Positive correlations between SF IL-1beta concentration and joint effusion (p < 0.01) and between SF TNF-alpha concentration and joint tenderness (p < 0.001) were observed. SF IL-1beta and TNF-alpha were significantly higher in patients with local complications of septic arthritis. In conclusion, high levels of IL-1beta, IL-6 and TNF-alpha were detected in SF of patients with non-GC septic arthritis. Only IL-1beta decreased significantly after day 7 of treatment, but IL-6 and TNF-alpha concentrations were persistently high. SF IL-1beta and TNF-alpha may be useful in predicting the outcome and complications of patients with this disease. (+info)

Slipped capital femoral epiphysis after septic arthritis of the hip in an adolescent: report of a case. (6/959)

Septic arthritis of the hip must be managed promptly to avoid the serious complications associated with the condition. In the case reported here, the diagnosis was delayed and was complicated by a slipped capital femoral epiphysis. The patient, an adolescent boy previously in good health, presented with a 2-week history of hip pain and systemic illness. Septic arthritis was diagnosed and was managed by incision and drainage and antibiotic therapy. Two weeks later he presented with a subcutaneous abscess and a slipped capital femoral epiphysis, which was pinned in situ. There was a 2.5-cm leg-length discrepancy. Avascular necrosis of the femoral head subsequently developed leaving the boy with a permanent disability. (+info)

Gamma interferon and interleukin-10 gene expression in synovial tissues from patients with early stages of Chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers. (7/959)

Genetically determined differences in interleukin-10 (IL-10) and gamma interferon (IFN-gamma) responses in mice correlate with clearance of Chlamydia pneumonitis infection. We measured the synovial expression of IL-10 and IFN-gamma and additional cytokine genes in patients who had recent-onset Chlamydia-associated arthritis (Chl-AA). IL-10 and IFN-gamma mRNA were relatively abundant in recent-onset Chl-AA. (+info)

Development of lyme arthritis in mice deficient in inducible nitric oxide synthase. (8/959)

Nitric oxide (NO) is a powerful antimicrobial agent and an important regulatory molecule of the innate immune response. To determine if NO has a role in experimental Lyme disease, arthritis-resistant DBA/2J and arthritis-susceptible C3H/HeJ mice were bred to be genetically deficient for inducible NO synthase (iNOS). Following footpad injection of Borrelia burgdorferi, arthritis was similar between iNOS-deficient and control animals regardless of their genetic background. Histologic examination and arthritis severity scores of ankles revealed no differences in arthritis development between iNOS-deficient and control animals. Despite being deficient in a key antimicrobial agent, iNOS-deficient mice had tissue levels of B. burgdorferi similar to those in control mice. Thus, NO does not have a critical role in susceptibility to Lyme arthritis through tissue damage via an overexuberant inflammatory response, nor is it required in resistance through the clearance of spirochetes from tissues. (+info)

Acute septic arthritis, infectious arthritis, suppurative arthritis, osteomyelitis, or joint infection is the invasion of a ... Joints with preexisting arthritis, such as rheumatoid arthritis, are especially prone to bacterial arthritis spread through the ... Crystal induced arthritis such as gout or pseudogout Inflammatory arthritis Rheumatoid arthritis Seronegative ... the signs and symptoms of septic arthritis can be deceptive and mimic other infectious and non-infectious disorders. In ...

https://en.wikipedia.org/wiki/Septic_arthritis

"Arthritis, Infectious". NORD (National Organization for Rare Disorders). 2009. Archived from the original on 21 February 2017. ... "Arthritis-Related Statistics: Prevalence of Arthritis in the United States". U.S. Centers for Disease Control and Prevention ( ... and all chronic forms of arthritis (e.g., costochondritis, gout, and rheumatoid arthritis). In gout, uric acid crystals cause ... bone') combined with arthritis (from ἀρθρῖτῐς, arthrîtis, lit. ''of or in the joint''), which is itself derived from arthr- ( ...

https://en.wikipedia.org/wiki/Osteoarthritis

"What is Reactive Arthritis?". Reactive Arthritis. 2019-02-06. Acheson, David; Allos, Ban Mishu (2001-04-15). "Campylobacter ... Campylobacteriosis is an infectious disease caused by bacteria of the genus Campylobacter. In most people who become ill with ... Another chronic condition that may be associated with Campylobacter infection is reactive arthritis. Reactive arthritis is a ... Most often, the symptoms of reactive arthritis will occur up to several weeks after infection. In 1886 a pediatrician, Theodor ...

https://en.wikipedia.org/wiki/Campylobacter_jejuni

Arthritis Care & Research. 73 (1): 1-9. doi:10.1002/acr.24495. PMID 33251700. S2CID 227237140. Evans, Laura; et al. (2021). " ... Infectious Diseases Society of America European Federation of Biotechnology International Society for Infectious Diseases The ... After the Society's inclusion of infectious diseases in the late 80s, the first ECCMID was held in 1991 in Oslo, Norway. ... The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) is a non-profit scientific international ...

https://en.wikipedia.org/wiki/European_Society_of_Clinical_Microbiology_and_Infectious_Diseases

Sallusto F, Lanzavecchia A (2002). "The instructive role of dendritic cells on T-cell responses". Arthritis Research. 4 Suppl 3 ... Clinical Infectious Diseases. 41 Suppl 7: S421-6. doi:10.1086/431992. PMID 16237641. ... drugs without having any affinity for μ-opioid receptor When microbes were first recognized as the cause of infectious diseases ...

https://en.wikipedia.org/wiki/Toll-like_receptor

The Journal of Infectious Diseases. 190 (10): 1869-1879. doi:10.1086/425042. ISSN 0022-1899. PMID 15499545. "Arthritis, ... Further research in this area may allude to clinical manifestations of this infectious disease, as there could be possible ... It was first known as mansonelliasis, which referred to an infectious disease of any of three parasite species, including ... Therefore, there is a great need for thorough parasitological studies in this area of tropical infectious diseases. The ...

https://en.wikipedia.org/wiki/Acanthocheilonemiasis

doi: 10.1093/rheumatology/key333 Isaacs D (2013). "Infectious risks associated with biologics". Hot Topics in Infection and ... Arthritis mutilans has also been called chronic absorptive arthritis, and may be seen in rheumatoid arthritis as well. ... reactive arthritis, gouty arthritis, systemic lupus erythematosus, and inflammatory bowel disease-associated arthritis. In ... Psoriatic arthritis is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. ...

https://en.wikipedia.org/wiki/Psoriatic_arthritis

Infectious Diseases Immunization Committee (1995). "Poststreptococcal arthritis". The Canadian Journal of Infectious Diseases. ... Reactive arthritis, also known as Reiter's syndrome, is a form of inflammatory arthritis that develops in response to an ... Arthritis occurring alone following sexual exposure or enteric infection is also known as reactive arthritis. Patients can also ... "Arthritis and Rheumatism". Retrieved 16 May 2011. eMedicine/Medscape (5 January 2010). "Reactive Arthritis". Retrieved 16 May ...

https://en.wikipedia.org/wiki/Reactive_arthritis

Blair, John E.; Reeves, David L. (1928). "The Placental Transmission of Bacteriophage". The Journal of Infectious Diseases. 42 ... Hallman, Frances A. (1934). "Rheumatoid (Atrophic) Arthritis". Archives of Internal Medicine. 53: 87-96. doi:10.1001/archinte. ... Staphylococcal Infections". Highlights of Research Progress in Allergy and Infectious Diseases. U.S. Department of Health, ... Hallman, Frances A. (1935). "Streptococcal agglutinins and antistreptolysins in rheumatoid (atrophic) arthritis" (PDF). The ...

https://en.wikipedia.org/wiki/John_Edward_Blair

No infectious agent has been consistently linked with RA and there is no evidence of disease clustering to indicate its ... Wikimedia Commons has media related to Rheumatoid arthritis. Rheumatoid arthritis at Curlie "Rheumatoid Arthritis". MedlinePlus ... "Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other ... in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis ...

https://en.wikipedia.org/wiki/Rheumatoid_arthritis

Schmitt, SK (June 2017). "Reactive Arthritis". Infectious Disease Clinics of North America (Review). 31 (2): 265-77. doi: ... It is associated with HLA B27 arthropathies, such as ankylosing spondylitis, psoriatic arthritis, and reactive arthritis. ... "Tendinitis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 12 April 2017. Retrieved 18 November 2018. ... thought to often precede psoriatic arthritis). A common autoimmune enthesitis is at the heel, where the Achilles tendon ...

https://en.wikipedia.org/wiki/Enthesitis

Schmitt, SK (June 2017). "Reactive Arthritis". Infectious Disease Clinics of North America (Review). 31 (2): 265-277. doi: ... It is associated with HLA B27 arthropathies such as ankylosing spondylitis, psoriatic arthritis, and reactive arthritis. ... Less common causes include infection, arthritis, gout, thyroid disease, and diabetes. Despite the injury of the tendon, there ... Less common causes include infection, arthritis, gout, thyroid disease, diabetes and the use of quinolone antibiotic medicines ...

https://en.wikipedia.org/wiki/Tendinopathy

Schmitt, SK (November 2017). "Reactive Arthritis". Infectious Disease Clinics of North America (Review). 31 (2): 265-77. doi: ... It is also a food-borne disease and are defined as diseases, usually either infectious or toxic in nature, caused by agents ... A small number of people afflicted with salmonellosis experience reactive arthritis, which can last months or years and can ... Freezing kills some Salmonella, but it is not sufficient to reliably reduce them below infectious levels. While Salmonella is ...

https://en.wikipedia.org/wiki/Salmonellosis

https://en.wikipedia.org/wiki/Tubercle_(bone)

Puius YA, Kalish RA (June 2008). "Lyme arthritis: pathogenesis, clinical presentation, and management". Infectious Disease ... an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities". Arthritis and Rheumatism. 20 ... clinical practice guidelines by the Infectious Diseases Society of America". Clinical Infectious Diseases. 43 (9): 1089-134. ... People with Lyme arthritis should limit their level of physical activity to avoid damaging affected joints, and in case of ...

https://en.wikipedia.org/wiki/Lyme_disease

Ahmeti, Salih; Ajazaj-Berisha, Lindita; Halili, Bahrije; Shala, Anita (Apr 2014). "Acute arthritis in Crimean-Congo hemorrhagic ... fever". Journal of Global Infectious Diseases. 6 (2): 79-81. doi:10.4103/0974-777X.132052. PMC 4049045. PMID 24926169. Heyman, ... injuries leading to a hemarthrosis are associated with cartilage damage that can lead to progressive degenerative arthritis. X- ...

https://en.wikipedia.org/wiki/Hemarthrosis

Infectious arthritis is another severe form of arthritis. It presents with sudden onset of chills, fever and joint pain. The ... The word arthritides is the plural form of arthritis, and denotes the collective group of arthritis-like conditions. ... Antiarthritics Arthritis Care (charity in the UK) Arthritis Foundation (US not-for-profit) Knee arthritis Osteoimmunology ... "Smoking and Rheumatoid Arthritis". NRAS. National Rheumatoid Arthritis Society. Retrieved 20 November 2020. "How is arthritis ...

https://en.wikipedia.org/wiki/Arthritis

... structural transitions of infectious proteins called prions); and intracellular protein quality control by energy-dependent ... August 1950-An arthritis program was established within the National Institute of Arthritis and Metabolic Diseases under Public ... "Arthritis, Musculoskeletal and Skin Diseases Home Page". nih.gov. "NIH/National Institute of Arthritis and Musculoskeletal and ... January 1975-The National Arthritis Act (P.L. 93-640) established the National Commission on Arthritis and Related ...

https://en.wikipedia.org/wiki/National_Institute_of_Arthritis_and_Musculoskeletal_and_Skin_Diseases

... and infectious arthritis in swine; and soft-tissue infections in small animals. While tylosin may be one appropriate ...

https://en.wikipedia.org/wiki/Tylosin

Juvenile idiopathic arthritis. Legg-Calvé-Perthes disease. Lyme disease, which is transmitted by ticks and is characterized by ... Infectious, such as Lyme disease and osteomyelitis. Neurological, such as spinal cord injury and vertebral degeneration. ... Septic arthritis, a severe infection of the joint that can lead to permanent joint damage. Spondyloarthropathies. Viral ... "Septic Arthritis". The Lecturio Medical Concept Library. Retrieved 27 August 2021. von Moos, R. Strasser, F. Gillessen, S. ...

https://en.wikipedia.org/wiki/Bone_pain

... the Paul Bunn Award in Infectious Disease; the Lee C. Howley Prize in Arthritis Research; and the Irish Society for Immunology ... He started his own group in the National Cancer Institute in 1989, and then moved to the National Institute of Arthritis and ... in 1981 for subspecialty training in allergy and immunology in the National Institute of Allergy and Infectious Diseases. He ... FoxP3+ regulatory T cells confer infectious tolerance in a TGF- -dependent manner". Journal of Experimental Medicine. 205 (9): ...

https://en.wikipedia.org/wiki/John_J._O'Shea

Melendez PR, Johnson RH (1991). "Bacteremia and septic arthritis caused by Moraxella catarrhalis". Reviews of Infectious ... This was also the second case of M. catarrhalis causing septic arthritis (although in the first case, no mention of bacteremia ... During the first reported case of M. catarrhalis causing bacteremia that was associated with septic arthritis, the microbe was ... Moraxella catarrhalis has also been linked with septic arthritis in conjunction with bacteremia. Although cases of bacteremia ...

https://en.wikipedia.org/wiki/Moraxella_catarrhalis

"Candida Arthritis: Analysis of 112 Pediatric and Adult Cases". Open Forum Infectious Diseases. 3 (1): ofv207. doi:10.1093/ofid/ ...

https://en.wikipedia.org/wiki/Candida_(fungus)

Infectious canine hepatitis is a sometimes fatal infectious disease of the liver. Canine herpesvirus is an infectious disease ... Symptoms in dogs include acute arthritis, anorexia and lethargy. There is no rash as is typically seen in humans. Ehrlichiosis ... Leptospirosis is an infectious disease caused by a spirochaete. Symptoms include liver and kidney failure and vasculitis. Lyme ... Echinococcosis is an infectious disease infecting dogs and sheep. Heartworm disease is caused by Dirofilaria immitis, which ...

https://en.wikipedia.org/wiki/List_of_dog_diseases

"Propionibacterium acnes postoperative shoulder arthritis: an emerging clinical entity". Clinical Infectious Diseases. 46 (12): ... Lim, Sung A.; Na, Kyung-Sun; Joo, Choun-Ki (September 2017). "Clinical Features of Infectious Keratitis Caused by ... "Propionibacterium Cutibacterium - late breaking news and a new name". Shoulder Arthritis / Rotator Cuff Tears: causes of ... The Journal of Infectious Diseases. 93 (1): 28-35. doi:10.1093/infdis/93.1.28. PMID 13069766. McLean RJ, Hussain AA, Sayer M, ...

https://en.wikipedia.org/wiki/Cutibacterium_acnes

On occasion, it causes cellulitis, osteomyelitis, and infectious arthritis. It is one cause of neonatal infection. Due to ... It can also cause cellulitis (skin infection) and infectious arthritis (inflammation of the joint). Naturally acquired disease ... Reviews of Infectious Diseases. 13 (Suppl 6): S463-S469. doi:10.1093/clinids/13.supplement_6.s463. PMID 1862277. Hosmer J, ... The Pediatric Infectious Disease Journal. 17 (9 Suppl): S204-S207. doi:10.1097/00006454-199809001-00026. PMID 9781764. "Signs ...

https://en.wikipedia.org/wiki/Haemophilus_influenzae

Progressive non-infectious anterior vertebral fusion (PAVF), later known as Copenhagen disease, was first fully described by ... Arthritis & Rheumatology. 69 (6): 1324. doi:10.1002/art.40081. PMID 28235247. Décarie JC, Babyn PS (1993). "Progressive ... "Orphanet: Progressive non infectious anterior vertebral fusion". www.orpha.net. 2013. Archived from the original on 2022-02-25 ... Sagittal MRI imaging provides accurate scans of the spine showing non-infectious fusion. CT scans can also be used to locate ...

https://en.wikipedia.org/wiki/Copenhagen_disease

Dendle, C.; Woolley, I. J.; Korman, T. M. (December 2006). "Rat-bite fever septic arthritis: illustrative case and literature ... International Journal of Infectious Diseases. 5 (3): 151-154. doi:10.1016/s1201-9712(01)90090-6. ISSN 1201-9712. PMID 11724672 ... Symptoms of RBF include sudden high temperature fevers with rigors, vomiting, headaches, painful joints/arthritis. A red, bumpy ... and arthritis of large joints can be seen. The organism can be cultivated in blood or articular fluid. The disease can be fatal ...

https://en.wikipedia.org/wiki/Rat-bite_fever

Dendle C, Woolley IJ, Korman TM (December 2006). "Rat-bite fever septic arthritis: illustrative case and literature review". ... and Bennett's principles and practice of infectious diseases (Eighth ed.). Philadelphia, PA. pp. 2629-2632. doi:10.1016/B978-1- ... European Journal of Clinical Microbiology & Infectious Diseases. 25 (12): 791-7. doi:10.1007/s10096-006-0224-x. PMID 17096137. ...

https://en.wikipedia.org/wiki/Spirillum_minus

Patients are usually no longer infectious once the rash has appeared. Teenagers and adults may present with a self-limited ... It manifests in painful swelling of the joints that feels similar to arthritis. Older children and adults with fifth disease ... In cases of arthropathy, such as those with arthritis or arthralgia, non-steroidal anti-inflammatories (NSAIDs) or other ant- ... Individuals with fifth disease are most infectious before the onset of symptoms. Typically, school children, day-care workers, ...

https://en.wikipedia.org/wiki/Fifth_disease

"Virus-like infectious agent (VLIA) is a novel pathogenic mycoplasma: Mycoplasma incognitus". The American Journal of Tropical ... Genotypic Characterization of Seven Strains of Mycoplasma fermentans Isolated From Synovial Fluids of Patients With Arthritis J ...

https://en.wikipedia.org/wiki/Mycoplasma_incognitus

Research on T-cell vaccination so far has focused mostly on multiple sclerosis and to a lesser extent on rheumatoid arthritis, ... The concept of T-cell vaccination is, at least partially, analogous to classical vaccination against infectious disease. ...

https://en.wikipedia.org/wiki/T-cell_vaccination

... including synovial tissue of patients with rheumatoid arthritis (RA), salivary glands of patients with Sjögren's syndrome, and ... "Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes". PLOS Pathogens. 11 (12): e1005285. doi:10.1371/journal. ...

https://en.wikipedia.org/wiki/Follicular_dendritic_cells

Kalliolias GD, Ivashkiv LB (2010). "Overview of the biology of type I interferons". Arthritis Research & Therapy. 12 Suppl 1 ( ... Long SS, Pickering LK, Prober CG (2012). Principles and Practice of Pediatric Infectious Disease. Elsevier Health Sciences. p. ... Yasu-ichi Nagano and Yasuhiko Kojima-two Japanese virologists working at the Institute for Infectious Diseases at the ... BMC Infectious Diseases. 7: 8. doi:10.1186/1471-2334-7-8. PMC 1810538. PMID 17319959. ...

https://en.wikipedia.org/wiki/Interferon

608 A physical examination and medical history are generally not enough to distinguish between infectious and non-infectious ... Swelling of multiple joints along with restricted range of motion may indicate arthritis instead.: p. ... 608 Unlike arthritis, except in severe cases prepatellar bursitis generally does not affect the range of motion of the knee, ... 608 a threshold significantly lower than that of septic arthritis (50,000 cells per microliter).: p. 360 A tuberculosis ...

https://en.wikipedia.org/wiki/Prepatellar_bursitis

Oral LP is a non infectious, chronic inflammatory condition that involves the oral mucosa and may be accompanied by skin ... Hellgren L (December 1970). "The prevalence of rheumatoid arthritis in different geographical areas in Sweden". Acta ...

https://en.wikipedia.org/wiki/Lichen_planus

Examples include methotrexate (used in chemotherapy and in treating rheumatic arthritis) and the protease inhibitors used to ... Agbowuro AA, Huston WM, Gamble AB, Tyndall JD (July 2018). "Proteases and protease inhibitors in infectious diseases". ... inflammatory cytokines and hence these inhibitors are used to treat a variety of inflammatory diseases in including arthritis, ...

https://en.wikipedia.org/wiki/Enzyme_inhibitor

It is also responsible for inflammation and autoimmunity with diseases such as rheumatoid arthritis, multiple sclerosis, and ... Infectious diseases, Apoptosis, Cell signaling, Cytokines). ...

https://en.wikipedia.org/wiki/Cell-mediated_immunity

But, when the arthritis is an isolated symptom, it is referred to as poststreptococcal reactive arthritis. This arthritis can ... The Lancet Infectious Diseases. The Lancet: Infectious Disease. 18 (2): 180-187. doi:10.1016/S1473-3099(17)30693-X. PMID ... Poststreptococcal reactive arthritis: The presentation of arthritis after a recent episode of group A streptococcal pharyngitis ... These criteria include arthritis, carditis, neurological issues, and skin findings. Diagnosis also depends on evidence of a ...

https://en.wikipedia.org/wiki/Scarlet_fever

The development of drugs for the treatment of infectious diseases was a major focus of early research and development efforts; ... White WB (May 2009). "Defining the problem of treating the patient with hypertension and arthritis pain". The American Journal ... Nonetheless, the dramatic decrease in deaths from infectious diseases that occurred prior to World War II was primarily the ... an anti-inflammatory medication used for arthritis. In the Bextra case, the government also charged Pfizer with illegally ...

https://en.wikipedia.org/wiki/Pharmaceutical_industry

RCT found that in blood samples taken after bouts of exhaustive exercise, there was a reduced response to an infectious ... Jacob S (2003). MSM the Definitive Guide: Nutritional Breakthrough for Arthritis, Allergies and More. Freedom Press. ISBN 978-1 ... "MSM for arthritis pain: Is it safe?". Expert Answers. Mayo Clinic. Retrieved 14 July 2015. Usha PR, Naidu MU (2004). " ...

https://en.wikipedia.org/wiki/Methylsulfonylmethane

Arthritis Res. 4 Suppl 3 (Suppl 3): S127-32. doi:10.1186/ar567. PMC 3240143. PMID 12110131. McKenna K, Beignon A, Bhardwaj N ( ... "Difference in production of infectious wild-type measles and vaccine viruses in monocyte-derived dendritic cells". Virus Res. ...

https://en.wikipedia.org/wiki/Dendritic_cell

Multi-omic data analysis has been employed to gather novel insights about the immune response to infectious diseases, such as ... "Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets". PLOS ONE. 10 (4): e0124254. ... The applications range from understanding host-pathogen interactions and infectious diseases, cancer, to understanding better ... ACS Infectious Diseases. 5 (4): 493-505. doi:10.1021/acsinfecdis.9b00080. ISSN 2373-8227. PMID 30857388. S2CID 75137107. Aderem ...

https://en.wikipedia.org/wiki/Multiomics

Post-infectious glomerulonephritis can also be caused by bacterial or viral infections. Streptococcal throat or skin infection ... Arthritis Care & Research. 64 (6): 797-808. doi:10.1002/acr.21664. PMC 3437757. PMID 22556106. Mok, Chi Chiu; Ying, King Yee; ...

https://en.wikipedia.org/wiki/Diffuse_proliferative_nephritis

The elderly and people with severe arthritis are at high risk for SCI because of defects in the spinal column. In nontraumatic ... Multiple sclerosis is a disease that can damage the spinal cord, as can infectious or inflammatory conditions such as ...

https://en.wikipedia.org/wiki/Spinal_cord_injury

Moffet's Pediatric Infectious Diseases: A Problem-oriented Approach. Lippincott Williams & Wilkins. pp. 145-. ISBN 978-0-7817- ... Seronegative rheumatoid arthritis[citation needed] Irritable bowel syndrome[citation needed] Chronic pain syndromes[citation ...

https://en.wikipedia.org/wiki/Wastebasket_diagnosis

The drug paralyses and kills the microfilariae causing fever, itching, and possibly oedema, arthritis and lymphadenopathy. ... Journal of Infectious Diseases. 187 (4): 714-7. doi:10.1086/367709. JSTOR 30085595. PMID 12599094. Murdoch ME, Hay RJ, ... Current Opinion in Infectious Diseases. 21 (6): 673-81. doi:10.1097/QCO.0b013e328315cde7. PMID 18978537. S2CID 26046513. Yates ... Infectious diseases with eradication efforts, Parasitic infestations, stings, and bites of the skin, Wikipedia medicine ...

https://en.wikipedia.org/wiki/Onchocerciasis

Mount Sinai Medical Center provides following clinical services: Allergy / Immunology Arthritis & Rheumatology Alzheimer's ... Emergency Medicine Endocrinology Family Medicine Gastroenterology General Surgery Gynecology Hospice Care Infectious Disease ...

https://en.wikipedia.org/wiki/Mount_Sinai_Medical_Center_(Miami)

As infectious diseases have become less lethal, and the most common causes of death in developed countries are now tumors and ... arthritis, and epilepsy then men do. Galen also hypothesized that there are three faculties. The natural faculty affects growth ... Eradication of infectious diseases is an international effort, and several new vaccines have been developed during the post-war ... Old ideas of infectious disease epidemiology were gradually replaced by advances in bacteriology and virology. The Russian ...

https://en.wikipedia.org/wiki/History_of_medicine

The synthetic amino-psoralen, amotosalen HCl, has been developed for the inactivation of infectious pathogens (bacteria, ... and rheumatoid arthritis). While cell-surface modification and ion channel blocking are two newly discovered mechanisms of ...

https://en.wikipedia.org/wiki/Psoralen

However, fibrates are associated with a number of adverse effects including arthritis, leg edema, polydipsia, and myalgias. ... and infectious agents. Urinary tract infection with E. coli is a particularly strong risk factor for PBC. A possible ...

https://en.wikipedia.org/wiki/Cholestasis

S. hyicus has also been noted as a cause of arthritis in young pigs in the absence of any signs of exudative epidermitis. The ... Another notable case is a man who was diagnosed with a case of infectious spondylodiscitis. A culture of his infected bone and ... "Importance of Staphylococcus hyicus ssp hyicus as a cause of arthritis in pigs up to 12 weeks of age". Australian Veterinary ... "Microbiological and laboratory studies on porcine arthritis". {{cite journal}}: Cite journal requires ,journal= (help) Hill, Bd ...

https://en.wikipedia.org/wiki/Staphylococcus_hyicus

Enthesitis Ankylosing spondylitis Juvenile rheumatoid arthritis psoriatic arthritis reactive arthritis Behçet's disease ... For non-infectious uveitis, women are more likely (57%) to be affected than men, possibly due to their higher prevalence of ... Rheumatoid arthritis is not uncommon in Asian countries as a significant association of uveitis. Sympathetic ophthalmia Behçet ... Vitamin D deficiency and smoking are risk factors for non-infectious uveitis. The prognosis is generally good for those who ...

https://en.wikipedia.org/wiki/Uveitis

Morshed, S.; Malek (February 2007). "Clostriduim cadaveris septic arthritis in a metastatic breast cancer patient". J. ... Clinical Infectious Diseases. 29 (5): 1354-1355. doi:10.1086/313491. PMID 10525006. Starr, S..E.; Killgore, Dowell (October ... Clinical Infectious Diseases. 25 (1): 160. doi:10.1086/516893. PMID 9243057.{{cite journal}}: CS1 maint: multiple names: ... Scandinavian Journal of Infectious Diseases. 38 (1): 59-78. doi:10.1080/00365540500388792. PMID 16338840. S2CID 38559710. Keto- ...

https://en.wikipedia.org/wiki/Clostridium_cadaveris

NRH may develop via autoimmune, hematological, infectious, neoplastic, vascular, or drug-related causes. It is associated with ... rheumatoid arthritis, Felty syndrome, myeloproliferative disorders, hereditary hemorrhagic telangiectasia (HHT, Osler-Weber- ...

https://en.wikipedia.org/wiki/Nodular_regenerative_hyperplasia

Cases discussed in Emerging Infectious Diseases in February 2014 show that A. algerae myositis caused fever, weight loss, ... It has caused severe myositis in patients taking immunosuppressive medication for rheumatoid arthritis or solid-organ ...

https://en.wikipedia.org/wiki/Anncaliia_algerae

Diseases that must be excluded in the diagnosis of iMCD include infectious diseases, such as HHV-8-associated MCD, Epstein-Barr ... Self-directed antibodies are commonly seen in autoimmune diseases such as systemic lupus erythematous and rheumatoid arthritis ... such as systemic lupus erythematosus and rheumatoid arthritis; and cancers, including lymphoma, multiple myeloma, and primary ...

https://en.wikipedia.org/wiki/Idiopathic_multicentric_Castleman_disease

Learn why people get infectious arthritis, tests needed and how it is treated. ... Infectious or septic arthritis is a bacterial infection of the joint. ... ClinicalTrials.gov: Arthritis, Infectious (National Institutes of Health) * ClinicalTrials.gov: Arthritis, Reactive (National ... One type of infectious arthritis is reactive arthritis. The reaction is to an infection somewhere else in your body. The joint ...

https://medlineplus.gov/infectiousarthritis.html

Post-Chikungunya Rheumatoid Arthritis, Saint Martin. Emerging Infectious Diseases. 2015;21(3):530-532. doi:10.3201/ ... rheumatoid arthritis, and psoriatic arthritis (2,4,5). Although the proportion of patients with chronic disease has decreased, ... Post-chikungunya chronic arthritis-our experience with DMARDs over two year follow up. J Assoc Physicians India. 2011;59:83-6 . ... A report of 21 cases of rheumatoid arthritis following chikungunya fever. A mean follow-up of two years. Joint Bone Spine. 2009 ...

https://wwwnc.cdc.gov/eid/article/21/3/14-1397_article

... infectious arthritis) include joint infection due to bacteria, virus or fungi. Low immunity, morbidity & mortality are other ... Septic Arthritis (Infectious Arthritis) - Joint Fluid & Tissue Infection. Septic arthritis (infectious arthritis) is an ... infectious arthritis) and it may affect to joints of the body. The common symptoms of septic arthritis (infectious arthritis) ... infectious arthritis), therefore it becomes essential to know more about causes of septic arthritis (infectious arthritis) and ...

http://www.home-remedies-for-you.com/blog/causes-of-septic-arthritis-infectious-arthritis.html

Infectious arthritis of native and prosthetic joints may be caused by viruses, or fungi, but the most common cause is bacteria. ... Acute Bacterial Arthritis. Epidemiology. The burden of septic arthritis in the general population is considerable. The ... Nonbacterial pathogens that may cause septic arthritis include viruses, fungi, and mycobacteria. Viral arthritis is often ... clinical presentation and treatment differ for these two forms of infectious arthritis, but both are associated with ...

https://www.the-hospitalist.org/hospitalist/article/122903/infectious-arthritis-native-and-prosthetic-joints

Background Septic arthritis (SA) results from the presence of microbial agents in a joint space. SA of the hip is a true ... Infectious agents. In neonates (aged , 2 mo), Staphylococcus aureus is the most common cause of septic arthritis (SA), but ... Thompson A, Mannix R, Bachur R. Acute pediatric monoarticular arthritis: distinguishing lyme arthritis from other etiologies. ... encoded search term (Pediatric Septic Arthritis) and Pediatric Septic Arthritis What to Read Next on Medscape ...

https://www.medscape.com/answers/970365-177537/what-is-the-pathogenesis-of-pediatric-septic-arthritis-sa

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease of unknown cause. The hallmark feature of this condition ... Infectious agents. For many decades, numerous infectious agents have been suggested as potential causes of RA, including ... For more information, see the Arthritis Center, as well as Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, and Rheumatoid ... Chapter 5: Ultrasound of Rheumatoid Arthritis. Bruno MA, Mosher TJ, Gold GE. Arthritis in Color: Advanced Imaging of Arthritis ...

http://emedicine.medscape.com/article/331715-overview

Nongonococcal infectious arthritis is an acute or subacute illness with potentially significant morbidity and mortality. It can ... encoded search term (Nongonococcal Infectious Arthritis) and Nongonococcal Infectious Arthritis What to Read Next on Medscape ... Nongonococcal Infectious Arthritis Clinical Presentation. Updated: Mar 09, 2021 * Author: Edward Dwyer, MD; Chief Editor: ... Smith JW, Chalupa P, Shabaz Hasan M. Infectious arthritis: clinical features, laboratory findings and treatment. Clin Microbiol ...

https://www.staging.medscape.com/answers/334286-169895/which-clinical-history-findings-are-characteristic-in-nongonococcal-infectious-arthritis

Infectious arthropathies. 712. Yes. Crystal arthropathies. 713. Arthropathy associated with other disorders classified ... 12.2 days with arthritis, 6.6 days without arthritis) and diabetes (15.4 days with arthritis, 8.2 days without arthritis) (11 ... by Arthritis Status. Characteristic. With Arthritis (n = 25,724). Without Arthritis (n = 33,251). P Valuea ... 7.9 days without arthritis; mentally unhealthy days: 4.8-5.2 days with arthritis, 4.2 days without arthritis) (12). As with ...

https://www.cdc.gov/pcd/issues/2017/16_0495.htm

John Burrow We dont often think of arthritis as being caused by an infectious agent, but rather consider it to be a byproduct ... We dont often think of arthritis as being caused by an infectious agent, but rather consider it to be a byproduct of old age ... There are certain risk factors that can increase a persons chance of contracting infectious arthritis, such as diabetes, ... If Septic Arthritis is suspected, it is important to quickly determine if a pathogen is present in the synovial fluid and to ...

https://www.osc-ortho.com/blog/septic-infectious-arthritis-john-d-burrow/

Articles provide the most up-to-date information on infectious diseases and their effects on global health. ... It offers global health professionals the latest scientific information on emerging infectious diseases and trends. ... Emerging Infectious Diseases is a peer-reviewed, monthly journal published by the Centers for Disease Control and Prevention ( ... After appropriate treatment, 13.3% of acute brucellosis cases progressed to chronic disease; arthritis was an early predictor. ...

http://cdc.gov/eid

Arthritis Caused by Nannizziopsis obscura, France. Emerging Infectious Diseases. 2022;28(9):1929-1931. doi:10.3201/ ... We report a case of septic arthritis caused by N. obscura.. In April 2019, a 56-year-old man, originally from Senegal and a ... We present a rare case of septic arthritis with necrotizing cellulitis caused by N. obscura in a patient in France who had ... This rare case of septic arthritis due to N. obscura occurred secondarily to a skin and soft tissue infection. Such severe ...

https://wwwnc-origin.cdc.gov/eid/article/28/9/22-0375_article

... works at Kuzell Institute for Arthritis and Infectious Dise and is well known for Mycobacterium Avium, Mycobacterium Avium ... Kuzell Institute for Arthritis & Infectious Diseases, San Francisco, USA Department of Immunology and Infectious Diseases, Palo ... Kuzell Institute for Arthritis and Infectious Diseases, Division of Infectious Diseases, California Pacific Medical Center, ... Kuzell Institute for Arthritis and Infectious Diseases, 2200 Webster Street, R305, San Francisco, CA 94115, U.S.A. ...

https://www.keyopinionleaders.com/Mycobacterium-Avium-Complex/Lowell-S-Young-Clinical-Microbiology-Laboratory-And-Div-dtetxuc-vh.html

Other clinical manifestations include peripheral arthritis, enthesitis, and extra-articular organ involvement. ... TNFi are also approved for the treatment of rheumatoid arthritis and psoriatic arthritis. Other approved indications include ... Non-infectious uveitis (adalimumab) Toxicities associated with TNFi include injection-site and infusion reactions. Increased ... Working status in patients with rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis: results from the British ...

https://www.medscape.com/answers/332945-70122/what-is-the-role-of-joint-replacement-in-the-treatment-of-ankylosing-spondylitis-as

Septic arthritis is an infection in the joint fluid (synovial fluid) and joint tissues. It occurs more often in children than ... Septic Arthritis (Infectious Arthritis) in Children. What is septic arthritis in children?. Septic arthritis is an infection in ... How is septic arthritis diagnosed in a child?. Early diagnosis of septic arthritis is important. It can prevent long-term ( ... Key points about septic arthritis in a child. * Septic arthritis is an infection in the joint fluid (synovial fluid) and joint ...

https://healthlibrary.somc.org/Library/DiseasesConditions/Pediatric/Orthopedic/90,P01730

The signs of septic arthritis include heat, swelling, and pain in one or more joints. There will typically be decreased range ... Osteoarthritis, other joint damage, or injections into a joint can also be root causes of septic arthritis. If a cat with ... Any trauma that penetrates a joint, or a surgery involving a joint, can result in septic arthritis. ... septic arthritis is very ill, they will be hospitalized and treated as necessary to become stabilized. Joint fluid will be ...

https://vcahospitals.com/know-your-pet/septic-arthritis-in-cats

... also called septic arthritis, and how it is treated by the Division of Rheumatology at Brigham and Womens Hospital. ... Infectious Arthritis #iw_comp1607841061731{}. Infectious arthritis, also called septic arthritis, is a type of arthritis caused ... The treatment for an infectious arthritis depends on the type of infection. For example, a bacterial or fungal arthritis is ... Most types of infectious arthritis are caused by bacteria either from the skin or blood stream. Viral and fungal infections can ...

http://www.handballinpanamerica.org/infectious-arthritis.html

Infectious Disease online now, exclusively on AccessPediatrics. AccessPediatrics is a subscription-based resource from McGraw ... The presenting symptoms of Lyme arthritis and gonococcal arthritis differ from typical septic arthritis. Lyme arthritis is a ... Septic Arthritis. In: Shah SS. Shah S.S.(Ed.),Ed. Samir S. Shah.eds. Pediatric Practice: Infectious Disease. McGraw Hill; 2009 ... Septic Arthritis." Pediatric Practice: Infectious Disease Shah SS. Shah S.S.(Ed.),Ed. Samir S. Shah. McGraw Hill, 2009, https ...

https://accesspediatrics.mhmedical.com/content.aspx?bookid=453§ionid=40249720

Categories: Arthritis, Infectious Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...

https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Arthritis,+Infectious&parentid=14006&catid=3525

Arthritis. *Arthritis, Infectious. *Asthma. *Astigmatism. *Attention Deficit Hyperactivity Disorder (ADHD). *Autism Spectrum ...

https://corp.credoreference.com/component/booktracker/edition/15848.html

... also known as infectious arthritis, may represent a direct invasion of joint space by various microorganisms, most commonly ... See also Pediatric Septic Arthritis, Pediatric Septic Arthritis Surgery, and Septic Arthritis Surgery. ... Infectious arthritis. Clin Infect Dis. 1995 Feb. 20 (2):225-30; quiz 231. [QxMD MEDLINE Link]. ... During the progression of infectious arthritis of the hip, this image was obtained early in the disease and shows only ...

https://reference.medscape.com/article/236299-overview

National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases; National Institute of Allergy and Infectious ... Part E of the subject questionnaire relates to arthritis. The battery of questions is adapted from the Arthritis Supplement ... National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases; National Institute of Allergy and Infectious ... The arthritis questions asked in the proxy question- naire are coded in section VO, cols. 3711-3716. E1 0671 Have you had pain ...

https://wonder.cdc.gov/wonder/sci_data/surveys/hanes/followup/type_txt/intrv824.asp

The conditions being studied were: cancer (3 studies); infectious diseases (2 studies); diabetes (1 study); rheumatoid ... arthritis (1 study); acute coronary syndrome (1 study); schizophrenia (1 study); and uveitis (1 study). The clinical trials ... with cancer or vascular diseases had lower therapeutic misconception scores compared with those with inherited or infectious ...

https://www.emro.who.int/emhj-volume-21-2015/volume-21-issue-3/investigating-the-informed-consent-process-therapeutic-misconception-and-motivations-of-egyptian-research-participants-a-qualitative-pilot-study.html

Learn about the different types of arthritis, how they differ and why its important. ... Infectious Arthritis. A bacterial, viral or fungal infection triggers infectious arthritis. It usually starts when an infection ... About Arthritis Common Topics. What Is Arthritis? Arthritis is not one disease. Learn about the different types of arthritis, ... Rheumatoid arthritis (RA) is the most common form of autoimmune inflammatory arthritis. Psoriatic arthritis (PsA) axial ...

https://www.arthritis.org/health-wellness/about-arthritis/understanding-arthritis/what-is-arthritis

... with Quizlet and memorize flashcards containing terms like What are risk factors for non-gonococcal acute bacterial arthritis ... What should be done when a pt with a joint prosthesis gets septic arthritis in that joint? ... What is the mortality rate of non-gonococcal septic arthritis if more than one joint is involved? ... Who is more likely to have more than one joint infected with non-gonococcal septic arthritis? ...

https://quizlet.com/316822805/septic-arthritis-and-gonococcal-arthritis-flash-cards/

Disease burden of infectious diseases in Europe: a pilot study. RIVM report 215011001.2007 RIVM, Centre for Infectious Disease ... Validation of an ELISA for the Diagnosis of recent Campylobacter infections in Guillain-Barre and reactive arthritis patients. ...

https://wwwn.cdc.gov/Nchs/Nhanes/2005-2006/SSSAL_D.htm

Juvenile idiopathic and infectious arthritis. *Osteoarthritis and rheumatoid arthritis. *Lupus, gout, and scleroderma ... Common conditions: arthritis, Crohn's disease, gout, lupus Our team cares for and treats Veterans with joint and ... Arthritis care for inflamed, swollen, or damaged joints. *Foot and ankle fracture treatment, repair of cartilage, torn tendons ... Infectious disease We evaluate and treat Veterans with infections including hepatitis, HIV/AIDS and tuberculosis. ...

https://www.va.gov/dayton-health-care/locations/dayton-va-medical-center/

Arthritis. Arthritis, Rheumatoid. Spondylarthritis. Joint Diseases. Musculoskeletal Diseases. Rheumatic Diseases. Connective ... Background : Inflammatory arthritis (rheumatoid arthritis (RA) or spondyloarthritis (SpA) are painful chronic diseases which ... Background Inflammatory arthritis (rheumatoid arthritis (RA) or spondyloarthritis (SpA) are painful chronic diseases which ... Rheumatoid Arthritis (RA) Spondyloarthritis (SpA) Other: Nurse-led self-management education intervention Not Applicable ...

https://www.clinicaltrials.gov/show/NCT02855320

Infectious arthritis (See: Infectious arthritis, also known asSeptic arthritis) * Infectious diseases ...

https://www.mayoclinic.org/diseases-conditions/index?letter=I

Infectious Disease *Arthritis, septic *Toxic synovitis *Lyme disease *Osteomyelitis *Rheumatic fever *Viral syndromes * ... Arthritis, reactive *Dermatomyositis *Henoch Schonlein purpura *Juvenile idiopathic arthritis *Systemic lupus erythematosus * ...

https://pediatriceducation.org/2014/05/19/what-causes-leg-pain/

There are various forms of arthritis among which some are associated with other diseases or infectio. (home-remedies-for-you.com)
There are certain risk factors that can increase a person's chance of contracting infectious arthritis, such as diabetes, alcoholism, sickle-cell anemia, immune-deficiency diseases, IV drug usage and rheumatic illnesses. (osc-ortho.com)
Emerging Infectious Diseases , 29 (3), 477-483. (cdc.gov)
Emerging Infectious Diseases , 29 (3), 484-492. (cdc.gov)
Department of Immunology and Infectious Diseases, Palo Alto Medical Foundation, California 94301. (keyopinionleaders.com)
Disease burden of infectious diseases in Europe: a pilot study. (cdc.gov)
The Arthritis Foundation's JA camp programs give kids with arthritis and related childhood rheumatic diseases the chance to make lasting memories. (arthritis.org)
Background : Inflammatory arthritis (rheumatoid arthritis (RA) or spondyloarthritis (SpA) are painful chronic diseases which impair quality of life and work capacity. (clinicaltrials.gov)
Emerging Infectious Diseases , 14 (1), 1-3. (cdc.gov)
Emerging Infectious Diseases , 14 (1), 4-9. (cdc.gov)
The North is a frontier for exploration of emerging infectious diseases and the large-scale drivers influencing distribution, host associations, and evolution of pathogens among persons, domestic animals, and wildlife. (cdc.gov)
Investigations of emerging infectious diseases associated with parasites in northern wildlife involved a network of multidisciplinary collaborators and incorporated geographic surveys, archival collections, historical foundations for diversity, and laboratory and field studies exploring the interface for hosts, parasites, and the environment. (cdc.gov)
Such integrative approaches serve as cornerstones for detection, prediction, and potential mitigation of emerging infectious diseases in wildlife and persons in the North and elsewhere under a changing global climate. (cdc.gov)
We're pleased to have with us Ms. Amanda Ingram, who's an Epidemiologist Supervisor working in the Infectious Diseases and Outbreaks Division at the Alabama Department of Public Health. (cdc.gov)
They summarize essential background vaccination à grande échelle, résument les information on their respective diseases informations essentielles sur les maladies et and vaccines, and conclude with the les vaccins associés et présentent en conclu- current WHO position concerning their sion la position actuelle de l'OMS concernant use in the global context. (who.int)
They may be confused with diseases such as chronic fatigue syndrome, rheumatoid arthritis, multiple sclerosis, depression, and even Alzheimer's disease. (sharecare.com)
If left untreated, Lyme arthritis can develop, which could mimic other inflammatory joint diseases. (sharecare.com)
In addition, diseases like rheumatoid arthritis and gout can predispose a person to infections of bursae and joints, and that possibility has to be considered and investigated. (everydayhealth.com)
Moreover, neutralization of TNF-a activity leads to improvement in models of inflammatory diseases and in patients with arthritis and sepsis. (cdc.gov)
certain localized infections - see body system-related chapters infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium [except obstetrical tetanus] (O98. (who.int)
Although many serious infectious diseases are bution of known infectious agents. (cdc.gov)
Scandinavian Journal of Infectious Diseases , 39 (1), 80-83. (vumc.nl)
Rijkeboer, A , Voskuyl, A & van Agtmael, M 2007, ' Fatal Salmonella enteritidis septicaemia in a rheumatoid arthritis patient treated with a TNF-α antagonist ', Scandinavian Journal of Infectious Diseases , vol. 39, no. 1, pp. 80-83. (vumc.nl)
It is essential that physicians consider autoinflammatory diseases as a possible diagnosis when they are presented with a patient who has recurrent fevers or other signs of systemic inflammation, especially since childhood, along with other symptoms such as rash and/or arthritis. (saidsupport.org)
Implementation of infectious diseases rapid molecular diagnostic tests and antimicrobial stewardship program involvement in acute-care hospitals. (cornell.edu)
The clinic is supervised by Dr. Taylor Carlisle, a highly-trained infectious diseases physician who is trained in tropical medicine and public health. (bsahs.org)
The clinical drivers of the market are growing incidence and prevalence of chronic diseases such as rheumatic disorders, cardiology, allergy and others, lower side effects associated with herbal medicines and lack of effectiveness of modern allopathy in treatment of diseases such as Hepatitis, arthritis and others. (medgadget.com)
After a literature review was conducted, a survey was distributed to pediatric rheumatology and infectious diseases physicians who treat PFAPA patients to query their management strategies. (acrabstracts.org)
The demand for infectious disease specialists is increasing every year, largely due to the increase in the number of infectious diseases in our society. (medicoleads.com)
Infectious disease doctors are responsible for diagnosing and treating patients impacted by infectious diseases. (medicoleads.com)
There is not a single relationship between the cause of an infection and its contagiousness, as there are bacterial diseases that are contagious and others that are not," explains Amesh Adalja, MD, an infectious disease physician and Senior Scholar at the Johns Hopkins Center for Health Security , adding that the same is true for the world's smorgasbord of viruses. (thehealthy.com)
ENR 5335 This course provides an introduction to the ecology of infectious diseases. (osu.edu)
We will investigate infectious disease transmission and control in single- and multi-host systems and for vector-borne diseases. (osu.edu)

We report post-chikungunya rheumatoid arthritis from Saint Martin, the epicenter of the current epidemic. (cdc.gov)
Swollen and stiff hands of a 70-year-old woman with post-chikungunya rheumatoid arthritis 10 months after acute infection with chikungunya virus, Saint Martin. (cdc.gov)
The patient's condition met the 2010 American College of Rheumatology/European League against Rheumatism criteria for rheumatoid arthritis ( https://www.rheumatology.org/practice/clinical/classification/ra/ra_2010.asp ), and the only cause observed for this disease was acute chikungunya. (cdc.gov)
For this corticosteroid-resistant, seronegative, and nondestructive post-chikungunya rheumatoid arthritis, methotrexate was prescribed at a weekly low dose after exclusion of contraindications, but the patient was not followed-up after she returned to Saint Martin. (cdc.gov)
The incidence of native joint septic arthritis is approximately 5 cases per 100,000 persons per year and is much higher in patients with rheumatoid arthritis (1,2). (the-hospitalist.org)
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease whose hallmark feature is a persistent symmetric polyarthritis (synovitis) that affects the hands and feet (see the image below). (medscape.com)
See Rheumatoid Arthritis: In and Out of the Joint , a Critical Images slideshow, to help identify the distinguishing features of RA as well as the signs of extra-articular manifestations of this disfiguring disease. (medscape.com)
Approximately 10% of individuals with bacterial arthritis have infection in multiple joints, particularly in the presence of a preexisting destructive joint disease (eg, rheumatoid arthritis) or compromising medical conditions (eg, diabetes and conditions necessitating glucocorticoid therapy). (medscape.com)
This pathogen causes 80% of infected joints affected by rheumatoid arthritis (RA). (medscape.com)
Sometimes Lyme arthritis can appear similar to other types of arthritis, such as rheumatoid arthritis osteoarthritis, and it may not be immediately recognized as Lyme arthritis unless you know that you have Lyme disease or that you had a tick bite. (verywellhealth.com)
Orencia (abatacept) for Rheumatoid Arthritis 'This medication made sense to me. (drugs.com)
Orencia (abatacept) for Rheumatoid Arthritis 'I was diagnosed with severe ra in 2009 with Sjögren's, Raynauds and Fibro. (drugs.com)
Orencia (abatacept) for Rheumatoid Arthritis 'This medication has worked spectacularly well for me. (drugs.com)
What are the new drugs for the treatment of rheumatoid arthritis (RA)? (drugs.com)
Orencia (abatacept) for Rheumatoid Arthritis 'I am a 49 year old male. (drugs.com)
Background - In community settings, disease-modifying antirheumatic drug (DMARD) use for rheumatoid arthritis (RA) falls short of treatment recommendations. (ices.on.ca)
[10] [6] Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. (wikipedia.org)
Osteoarthritis affects more than 3.8% of people, while rheumatoid arthritis affects about 0.24% of people. (wikipedia.org)
Stiffness and joint pain are also commonly associated with rheumatoid arthritis (RA). (sharecare.com)
Rheumatoid arthritis may also cause morning stiffness, which may not be the case with Lyme. (sharecare.com)
There are also specific biomarkers for rheumatoid arthritis that are used to diagnose this chronic inflammatory condition. (sharecare.com)
We present a case of tuberculous peritonitis in a 46-year-old woman with rheumatoid arthritis treated with adalimumab, and we review the association between anti-tumour necrosis factor therapy and tuberculosis. (scirp.org)
Herein, we present a case of tuberculous peritonitis in a patient with rheumatoid arthritis treated with adalimumab. (scirp.org)
This means CBD can help with symptom relief in common types of arthritis, including osteoarthritis and rheumatoid arthritis. (healthcanal.com)
Inflammation may be caused by a systemic arthritis such as rheumatoid arthritis , gout , and others. (everydayhealth.com)
The present report describes the case of a 6-year-old boy with a history of rheumatoid arthritis who presented with pain, swelling, and redness in the right TMJ region, as well as limited jaw opening, closure, and lateral excursion bilaterally. (bvsalud.org)
We report a patient with a rare presentation of extra-intestinal salmonellosis after infliximab therapy for rheumatoid arthritis. (vumc.nl)
According to the Hawai'i State Department of Health Behavioral Risk Factor Surveillance Survey (BRFSS), 41.4% of Native Hawaiian elders (age 65 years and older) said that they had been told by a doctor or other health professional that they have some form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia. (stanford.edu)
Researchers characterized the IgA anti-citrulline protein antibodies responses in the saliva and serum in relation to the clinical picture and to risk factors among patients with rheumatoid arthritis. (rheumatologyadvisor.com)
The presence of salivary immunoglobulin (Ig)A anti-citrulline protein antibodies (ACPAs) may identify patients with rheumatoid arthritis (RA) who have higher disease activity, according to data published in Arthritis Research & Therapy . (rheumatologyadvisor.com)
Roos Ljungberg K, Börjesson E, Martinsson K, Wetterö J, Kastbom A, Svärd A. Presence of salivary IgA anti-citrullinated protein antibodies associate with higher disease activity in patients with rheumatoid arthritis . (rheumatologyadvisor.com)
ORAL Surveillance, evaluating tofacitinib in rheumatoid arthritis patients, as a result of subsequent events or developments. (micronus.xyz)

The causes of septic arthritis (infectious arthritis) can include infection by bacteria and it may be caused by viruses and fungi. (home-remedies-for-you.com)
Therefore, it becomes essential to know more about causes of septic arthritis (infectious arthritis) to prevent its serious side effects. (home-remedies-for-you.com)
Infection in the joint is one of the common causes of septic arthritis (infectious arthritis) and it occurs when bacteria reaches a joint. (home-remedies-for-you.com)
The causes of septic arthritis (infectious arthritis) commonly found in young children and young babies. (home-remedies-for-you.com)
However, hemophilus influenzae and gram-negative bacteria are common causes of septic arthritis (infectious arthritis).Gonococci, staphylococci, streptococci, and mycobacteriums are the causes of septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Fungal infection is one of the common causes of septic arthritis (infectious arthritis) and it may occur in very rare condition. (home-remedies-for-you.com)
Viruses are the most common cause of septic arthritis (infectious arthritis) and it may affect to joints of the body. (home-remedies-for-you.com)
The common symptoms of septic arthritis (infectious arthritis) include joint pain and joint swelling in one or more joints. (home-remedies-for-you.com)
These causes of septic arthritis (infectious arthritis) can be found in approximately 10 percent of patients and it affects multiple joints. (home-remedies-for-you.com)
The bacteria may enter the body in variety of ways, the most common causes of septic arthritis (infectious arthritis) is infection that spreads from another source from source inside the body like ear infections is the common causes of septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Sometimes, infected wounds may cause septic arthritis (infectious arthritis) like open fractures or bones that penetrate through the skin. (home-remedies-for-you.com)
Foreign objects may penetrate the skin and therefore, it may cause septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Trauma is another cause behind septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Moreover, researchers are finding new ways to know more about causes of septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Additionally, there are several other factors responsible for septic arthritis (infectious arthritis), therefore it becomes essential to know more about causes of septic arthritis (infectious arthritis) and its symptoms. (home-remedies-for-you.com)
Septic arthritis (infectious arthritis) is an infection of the joint fluid and joint tissues. (home-remedies-for-you.com)
Septic arthritis is a type of infection that affects the joint. (home-remedies-for-you.com)
The burden of septic arthritis in the general population is considerable. (the-hospitalist.org)
The most common causes of bacterial septic arthritis are outlined in Table 1. (the-hospitalist.org)
Polymicrobial floras are found in up to 8% of cases of septic arthritis. (the-hospitalist.org)
Nonbacterial pathogens that may cause septic arthritis include viruses, fungi, and mycobacteria. (the-hospitalist.org)
Onset of Ki ngella kingae septic arthritis in pediatric patients likewise is typically insidious, and clinical manifestations tend to be milder than those of septic arthritis from other bacteria. (medscape.com)
Septic arthritis in immunocompetent and immunosuppressed hosts. (medscape.com)
Momodu II, Savaliya V. Septic Arthritis. (medscape.com)
Septic Arthritis: An Evidence-Based Review of Diagnosis and Image-Guided Aspiration. (medscape.com)
Case Studies and Literature Review of Pneumococcal Septic Arthritis in Adults. (medscape.com)
Kingella kingae as the Main Cause of Septic Arthritis: Importance of Molecular Diagnosis. (medscape.com)
Chen Y, Huang Z, Fang X, Li W, Yang B, Zhang W. Diagnosis and treatment of mycoplasmal septic arthritis: a systematic review. (medscape.com)
Three-decade trends in the distribution of organisms causing septic arthritis in native joints: Single-center study of 374 cases. (medscape.com)
Gupta MN, Sturrock RD, Field M. A prospective 2-year study of 75 patients with adult-onset septic arthritis. (medscape.com)
Considered a medical emergency when it occurs, septic arthritis can completely destroy a joint in a matter of days and can spread throughout the body. (osc-ortho.com)
In this article, I will discuss the causes of Septic Arthritis and the treatments available. (osc-ortho.com)
To make a diagnosis of septic arthritis , I listen to the patient describe their symptoms and ask about the speed at which the pain and inflammation developed. (osc-ortho.com)
If Septic Arthritis is suspected, it is important to quickly determine if a pathogen is present in the synovial fluid and to then isolate the microorganism that is causing the infection. (osc-ortho.com)
Drainage of infected joint fluid is required for the treatment of septic arthritis. (osc-ortho.com)
What is septic arthritis in children? (somc.org)
What causes septic arthritis in a child? (somc.org)
The most common type of bacteria that cause septic arthritis is Staphylococcus aureus, or staph. (somc.org)
Which children are at risk for septic arthritis? (somc.org)
Septic arthritis may occur without any known risk factors. (somc.org)
What are the symptoms of septic arthritis in a child? (somc.org)
How is septic arthritis diagnosed in a child? (somc.org)
Early diagnosis of septic arthritis is important. (somc.org)
How is septic arthritis treated in a child? (somc.org)
Septic arthritis often needs treatment right away with antibiotics if bacteria are the source of infection. (somc.org)
What are possible complications of septic arthritis in a child? (somc.org)
Septic arthritis can cause joint damage. (somc.org)
My cat was diagnosed with septic arthritis. (vcahospitals.com)
Septic arthritis occurs when bacteria or another infectious agent is introduced into one (or more) joints, leading to painful inflammation. (vcahospitals.com)
What are the signs of septic arthritis? (vcahospitals.com)
What kinds of infectious agents cause septic arthritis? (vcahospitals.com)
Bacteria that can live and grow in the presence of oxygen (aerobic bacteria) and bacteria that can live and grow in the absence of oxygen (anaerobic bacteria), and fungal organisms can all cause septic arthritis. (vcahospitals.com)
If septic arthritis is suspected, your cat's blood will be taken to look for evidence infection and inflammation. (vcahospitals.com)
Are there any specific risk factors that set the stage for septic arthritis? (vcahospitals.com)
Any trauma that penetrates a joint, or a surgery involving a joint, can result in septic arthritis. (vcahospitals.com)
Osteoarthritis, other joint damage, or injections into a joint can also be root causes of septic arthritis. (vcahospitals.com)
Medications that suppress the immune system can also influence the development of septic arthritis. (vcahospitals.com)
If your cat has septic arthritis and is very ill, they will be hospitalized and treated as necessary to become stabilized. (vcahospitals.com)
Some cats with septic arthritis require surgical opening of the joint, removal of abnormal tissue, and copious lavage. (vcahospitals.com)
Infectious arthritis, also called septic arthritis, is a type of arthritis caused by an infection in the joint. (handballinpanamerica.org)
Septic, pyogenic, and suppurative arthritis are the names given to the inflammation of the joint space caused by the presence of bacteria or fungi. (mhmedical.com)
Septic arthritis is more common in childhood than in any other period of human life and more than half of cases are diagnosed in individuals younger than 20 years of age. (mhmedical.com)
Since septic arthritis usually has a hematogenous origin, the age distribution of pediatric patients with joint infection is markedly skewed, reflecting the increased attack rate of bacteremia in early childhood. (mhmedical.com)
1 Since a significant fraction of suspected cases of septic arthritis remains bacteriologically unconfirmed, the true incidence of the disease is uncertain. (mhmedical.com)
2 Several pediatric subpopulations are at increased risk for septic arthritis, as summarized in Table 48-1 . (mhmedical.com)
Occasionally, septic arthritis results by direct inoculation of bacteria in the joint by penetrating trauma, bites, intra-articular injections (particularly corticosteroids) or a surgical procedure. (mhmedical.com)
The term Septic Arthritis (SA) represents an invasion of a joint space by a variety of microorganisms, most commonly bacteria. (medscape.com)
Septic arthritis is increasingly common among persons older than 65 years, among immunosuppressed individuals, and among those with various comorbidities such as diabetes. (medscape.com)
Fifty-six percent of patients with septic arthritis are male. (medscape.com)
The pathogen of Lyme disease , Borrelia burgdorferi, commonly produces a septic arthritis picture. (medscape.com)
Brucella may cause septic arthritis in areas where cattle are not vaccinated. (medscape.com)
Acute septic arthritis: remember gonorrhea. (medscape.com)
Saini A, Eichenseer C, Meyers A, Frousiakis P. Septic gonococcal arthritis in a pediatric patient: Rare case report. (medscape.com)
[6] Other types include gout , lupus , fibromyalgia , and septic arthritis . (wikipedia.org)
This form of arthritis is also called septic arthritis, and the infected joint is referred to as a "septic joint. (humanillnesses.com)
Staphylococcus (stah-fih-lo-KAH-kus) or Streptococcus (strep-tuh-KAH-kus) bacteria are the culprits in most cases of septic arthritis. (humanillnesses.com)
Septic arthritis is more common in the large joints, with the knee and hip most frequently affected. (bvsalud.org)
Background: Childhood pyogenic septic arthritis and its associated musculoskeletal morbidity is an important health concern in developing countries. (bvsalud.org)
The aim of this study was to determine the pattern and outcome of childhood septic arthritis in our environment. (bvsalud.org)
Materials and Methods: This was a retrospective study of all the children seen with pyogenic septic arthritis in Federal Teaching Hospital Abakaliki between January 2005 and December 2015. (bvsalud.org)
Results: Childhood septic arthritis accounted for 44 (83%) of the 53 patients seen with pyogenic septic arthritis. (bvsalud.org)
Conclusion: In our setting, pyogenic septic arthritis is predominantly a childhood health problem and children under 5 years of age are the most vulnerable. (bvsalud.org)
Clinical findings were similar to our case series although complications, particularly endocarditis and septic arthritis, occurred in approximately a third of cases. (nsw.gov.au)

Another form of reactive arthritis starts with eating food or handling something that has bacteria on it. (medlineplus.gov)
Infectious arthritis of native and prosthetic joints may be caused by viruses, or fungi, but the most common cause is bacteria. (the-hospitalist.org)
The bacteria that cause prosthetic joint arthritis vary depending on the stage of infection as defined by the elapsed time after implantation surgery (Table 1 on page 31). (the-hospitalist.org)
Most types of infectious arthritis are caused by bacteria either from the skin or blood stream. (handballinpanamerica.org)
If present, the specific bacteria or other infectious agent can be identified for treatment. (handballinpanamerica.org)
Microbiome, microbes, microorganisms - these terms may be confusing, but the types of bacteria living in and on our bodies can impact arthritis. (arthritis.org)
Lyme arthritis is a chronic condition that occurs when the bacteria that cause Lyme disease lead to inflammation of joint tissues. (verywellhealth.com)
Lyme arthritis occurs when Lyme disease bacteria enter joint tissues and cause inflammation. (verywellhealth.com)
Since the Borrelia bacteria invade the sensitive tissues that line the joints, they can cause damage to the cartilage, resulting in Lyme arthritis. (verywellhealth.com)
The unique peptidoglycan structure of the Borrelia bacteria contributes to this organism's ability to cause chronic Lyme arthritis. (verywellhealth.com)
Artificial Joint Infectious Arthritis Artificial joints can become infected by bacteria. (merckmanuals.com)
Sometimes bacteria enter the bursa and an infection sets in, called infectious bursitis. (everydayhealth.com)
leukocytes are specialized white blood cells that can destroy infectious microorganisms such as bacteria, parasites, and viruses. (humanillnesses.com)
Most of the time, bacteria cause infectious arthritis. (humanillnesses.com)

Infectious arthritis is an infection in the joint. (medlineplus.gov)
Sometimes, reactive arthritis is set off by an infection in the bladder, or in the urethra, which carries urine out of the body. (medlineplus.gov)
Acute bacterial arthritis is a potentially serious and rapidly progressive infection that may involve native or prosthetic joints. (the-hospitalist.org)
Viral arthritis is often associated with a systemic febrile illness and other manifestations of infection such as rash. (the-hospitalist.org)
The treatment for an infectious arthritis depends on the type of infection. (handballinpanamerica.org)
Reactive arthritis represents a sterile inflammatory process that may be triggered by an extra-articular infection. (medscape.com)
Typical symptoms of Lyme disease occur hours to weeks following the infection, with Lyme arthritis typically presenting itself any time within the first four weeks to several months after the initial infection. (verywellhealth.com)
Gonococcal arthritis and disseminated gonococcal infection are treated with antibiotics. (medscape.com)
Ceftriaxone is the drug of choice for disseminated gonococcal infection or gonococcal arthritis, according to guidelines developed by the Centers for Disease Control and Prevention (CDC). (medscape.com)
Cefotaxime is a third-generation cephalosporin used as an alternative to ceftriaxone for treatment of disseminated gonococcal infection or gonococcal arthritis. (medscape.com)
Gonococcal arthritis (disseminated gonococcal infection). (medscape.com)
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus) is found to be associated with 617 drugs and 384 conditions by eHealthMe. (ehealthme.com)

N. gonorrhoeae is a significant cause of bacterial arthritis in sexually active adults and adolescents (19) and Kingella kingae and Haemophilus influenzae are likely pediatric isolates (20,21). (the-hospitalist.org)
The clinical course of bacterial arthritis is typically acute in onset. (medscape.com)
The most commonly affected joint in persons with bacterial arthritis is the knee. (medscape.com)
A common cause of bacterial arthritis is Staphylococcus which lives on our skin. (handballinpanamerica.org)
For example, a bacterial or fungal arthritis is treated with antibiotics, while a viral arthritis will typically resolve on its own. (handballinpanamerica.org)
Balsa A, Martin-Mola E. Infectious arthritis I: bacterial arthritis. (medscape.com)

One type of infectious arthritis is reactive arthritis. (medlineplus.gov)
What Is Reactive Arthritis? (medlineplus.gov)
Validation of an ELISA for the Diagnosis of recent Campylobacter infections in Guillain-Barre and reactive arthritis patients. (cdc.gov)
The American College of Rheumatology report that chlamydia infections can also cause reactive arthritis . (medicalnewstoday.com)
Quo vadis reactive arthritis? (wjgnet.com)
Reactive Arthritis Update: Spotlight on New and Rare Infectious Agents Implicated as Pathogens. (wjgnet.com)
Thus, shigellosis and campylobacteriosis have been associated with the development of reactive arthritis, either alone or as part of a constellation of arthritis, conjunctivitis, and urethritis known as Reiter's syndrome [12]. (pharmiweb.com)
Severe symptoms and invasive infections can also occur, and persons with Campylobacter infections are at increased risk for three post-infectious complications: Guillain-Barre syndrome (GBS), reactive arthritis, and irritable bowel syndrome. (cdc.gov)

Nongonococcal infectious arthritis is an acute arthritis, which occurs due to morbidity and mortality. (home-remedies-for-you.com)
If there are signs of very acute inflammation, such as swelling, redness, heat over the skin, and severe pain, infectious bursitis should be suspected, and I recommend immediate medical attention. (everydayhealth.com)
Findacode.com doesn't have a Joint under arthritis either: [CODE]Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) M19.90 Non-specific code 13. (aapc.com)

Most kinds of arthritis cause pain and swelling in your joints. (medlineplus.gov)
Arthritis is a condition in which the joints get severely affected. (home-remedies-for-you.com)
Parvovirus B19 is the most common viral arthritide, presenting as a symmetric polyarticular arthritis involving the joints of the hand as well as larger joints (26). (the-hospitalist.org)
This imaging test uses a tiny amount of a radioactive substance to look for arthritis changes in the joints. (somc.org)
Common arthritis symptoms include swelling, pain, stiffness and diminished range of motion in joints. (arthritis.org)
Some types of arthritis affect the heart, eyes, lungs, kidneys and skin as well as the joints. (arthritis.org)
Lyme arthritis usually involves only a few joints, and it is likely to be asymmetrical-it does not affect both sides of the body the same way. (verywellhealth.com)
With Lyme arthritis, the joints tend to swell up significantly and the pain and swelling tend to come and go. (verywellhealth.com)
This leads to an inflammatory immune response that rids the body of the remaining peptidoglycans-this immune process also produces inflammation around the joints, which leads to the symptoms of Lyme arthritis. (verywellhealth.com)
Arthritis is a term often used to mean any disorder that affects joints . (wikipedia.org)

Arthritis, including rheumatic conditions, is a highly prevalent (29%) chronic condition in Medicare beneficiaries and is a leading cause of disability (1-3). (cdc.gov)
An undifferentiated arthritis is an arthritis that does not fit into well-known clinical disease categories, possibly being an early stage of a definite rheumatic disease . (wikipedia.org)
He has published research regarding infectious arthritis, medical ethics, and diagnostic test performance in rheumatic disease. (harvard.edu)
Arthritis, fibromyalgia, chronic fatigue syndrome, or any other mechanic or degenerative non-inflammatory rheumatic disease. (who.int)

Individuals with mycobacterial or fungal arthritis also tend to have a much more indolent or subacute prodrome before the diagnosis is considered. (medscape.com)
A new arthritis diagnosis can be overwhelming. (arthritis.org)
And contrary to popular belief, chronic Lyme disease isn't a recognized medical diagnosis, according to Danial Kaswan, MD, an infectious disease specialist affiliated with Aventura Hospital and Medical Center in Aventura, Florida. (sharecare.com)

Osteoarthritis (OA) is by far the most common type of arthritis. (arthritis.org)
Arthritis, osteoarthritis, tendonitis, bursitis and as an adjunct in the treatment of infectious processes that cause inflammation and pain. (jetpharms.com)

For most, Lyme arthritis is highly treatable with antibiotics within 30 days. (verywellhealth.com)
Even Dr. Allen Steere, who first described Lyme arthritis in 1979, prescribes longer courses of antibiotics. (lymedisease.org)

Timely recognition of emerging infections requires such as acquired immunodeficiency syndrome (AIDS) early warning systems to detect new infectious dis- and TB vividly illustrate that no nation can be compla- eases before they become public health crises. (cdc.gov)

The PFAPA Work Group of CARRA (Childhood Arthritis and Rheumatology Research Alliance) developed CTPs for PFAPA that will lead to improved characterization of a well-defined cohort and optimal treatment. (acrabstracts.org)

Arthritis is a common condition characterized by joint pain and inflammation. (healthcanal.com)
Although more research is needed, early studies [1] indicate that CBD and other cannabinoids may relieve the pain and inflammation involved in arthritis. (healthcanal.com)
Better yet, there's some evidence that CBD may have a positive effect on the inflammation that causes some types of arthritis, which means it may help the condition directly. (healthcanal.com)
Research both in the laboratory and in humans demonstrates that omega-3s can not only reduce laboratory test results for inflammation but also decrease symptoms of inflammation associated with arthritis and bursitis. (everydayhealth.com)

Arthritis is associated with diminished health-related quality of life (HRQoL) in several studies of adults aged 18 years or older, many of which used the Centers for Disease Control and Prevention (CDC) Healthy Days (or HRQoL-4) instrument (7-12). (cdc.gov)

001). Older adults with arthritis and either congestive heart failure, chronic obstructive pulmonary disease, diabetes, or hypertension reported significantly more adjusted physically, mentally, and total unhealthy days than older adults without arthritis but with the same chronic conditions. (cdc.gov)
Almost half of people with heart disease or diabetes and one-third of those with obesity have arthritis (4,5). (cdc.gov)
We combined administrative claims diagnoses of older adults with Healthy Days survey data to 1) characterize the relationship between arthritis and HRQoL in older adults and 2) assess the impact of comorbid arthritis on HRQoL among those with coronary artery disease, congestive heart failure, chronic obstructive pulmonary disease, diabetes, or hypertension. (cdc.gov)
the interaction between diabetes and arthritis was positive, suggesting that these two conditions have synergistic effects such that having both conditions was more disabling than would be expected by the effects of each individual condition. (healthcare-economist.com)

García-De La Torre I, Nava-Zavala A. Gonococcal and nongonococcal arthritis. (medscape.com)
Tuttle CS, Van Dantzig T, Brady S, Ward J, Maguire G. The epidemiology of gonococcal arthritis in an Indigenous Australian population. (medscape.com)

Le présent document remplace la précédente note de synthèse on hepatitis B vaccines.2 It provides updated informa- sur les vaccins anti-hépatite B, publiée par l'OMS en 2009.2 Il tion on hepatitis B vaccines and their storage, transport fournit des informations actualisées sur les vaccins anti-hépa- and deployment. (who.int)
Ces recommandations soulignent en importance of vaccination of all infants at birth as particulier l'importance de la vaccination à la naissance de tous the most effective intervention for the prevention of les nourrissons, une intervention qui constitue le moyen le plus hepatitis B virus-associated disease worldwide. (who.int)

Also known as infectious bursitis. (rxlist.com)

[13] [6] Recommended medications may depend on the form of arthritis. (wikipedia.org)
Its writing was motivated by my wish to help a friend who suffers from a highly debilitating form of arthritis for which conventional approaches are mostly inadequate-as inadequate as they are for all other degenerative chronic conditions. (healthfully.net)

We sought to determine whether this relationship persisted in an older population using claims-based arthritis diagnoses and whether people who also had arthritis and at least 1 of 5 other chronic conditions had lower HRQoL. (cdc.gov)
In older adults, having arthritis is associated with lower HRQoL and even lower HRQoL among those with at least 1 of 5 other common chronic conditions. (cdc.gov)
Because arthritis is so common among older adults, improving HRQoL depends on managing both underlying chronic conditions and any accompanying arthritis. (cdc.gov)
Severe arthritis can result in chronic pain, difficulty performing daily activities and make walking and climbing stairs painful and grueling. (arthritis.org)
Lyme arthritis is considered one of the most common chronic conditions associated with Lyme disease. (verywellhealth.com)
Nationally recognized infectious disease and chronic disease health care providers will contribute their perspective and answer questions about why getting vaccinated against the flu is a priority this year, particularly for those living with chronic conditions such as inflammatory arthritis. (creakyjoints.org)
The Global Healthy Living Foundation is a 501(c)(3) non-profit organization whose mission is to improve the quality of life for people living with chronic illnesses (such as arthritis, osteoporosis, migraine, psoriasis, inflammatory bowel disease, and cardiovascular disease) by advocating for improved access to health care at the community, state, and federal levels, and amplifying education and awareness efforts within its social media framework. (creakyjoints.org)
Not surprisingly, among very elderly Palauans (86 years of age and older), arthritis was reported to be the most common chronic illness (Jensen & Polloi, 1984, 1988). (stanford.edu)

Moreover, there is no known way to prevent viral arthritis. (home-remedies-for-you.com)

Influenza, commonly known as "the flu", is an infectious disease caused by the influenza virus. (primepharmacyng.com)

Arthritis Rheumatol. (cornell.edu)

More than 20 million individuals with arthritis have severe limitations in function on a daily basis. (wikipedia.org)

The epidemiology, pathophysiology, repertoire of potential infecting pathogens, clinical presentation and treatment differ for these two forms of infectious arthritis, but both are associated with significant morbidity and mortality. (the-hospitalist.org)
Smith JW, Chalupa P, Shabaz Hasan M. Infectious arthritis: clinical features, laboratory findings and treatment. (medscape.com)
The phase IV clinical study analyzes which people take Sutent and have Enteritis infectious. (ehealthme.com)

Mycobacterial and fungal arthritis. (medscape.com)
These agents are used when fungal arthritis, such as candidal arthritis, is documented. (medscape.com)

Thought you might appreciate this item(s) I saw in The Pediatric Infectious Disease Journal. (lww.com)
A core group of PFAPA experts including pediatric rheumatologists, infectious disease specialists and immunologists comprised the CARRA PFAPA Workgroup. (acrabstracts.org)

Learn about the different types of arthritis, how they differ and why it's important. (arthritis.org)
the term refers to joint pain or joint disease, and there are more than 100 types of arthritis and related conditions. (arthritis.org)
People of all ages, races and sexes live with arthritis, and it is the leading cause of disability in the U.S. It's most common among women, and although it's not a disease of aging, some types of arthritis occur in older people more than younger people. (arthritis.org)
[2] [3] In some types of arthritis, other organs are also affected. (wikipedia.org)
There are over 100 types of arthritis. (wikipedia.org)
Pain, which can vary in severity, is a common symptom in virtually all types of arthritis. (wikipedia.org)
In comparison, prescription drugs typically only focus on pain relief instead of improving the root cause of certain types of arthritis. (healthcanal.com)

Epstein-Barr virus (EBV) is a wide-spread human herpesvirus that is highly associated with infectious mononucleosis and several malignancies. (biomedcentral.com)

To diagnose infectious arthritis, your health care provider may do tests of your blood, urine, and joint fluid. (medlineplus.gov)
Arthrocentesis (sampling joint fluid) will also be performed, and the fluid will be assessed for the presence of inflammatory cells, as well as cultured to determine what infectious agent is present. (vcahospitals.com)
Arthritis can also cause permanent joint changes. (arthritis.org)
Many arthritis sufferers use CBD as an alternative remedy for easing joint pain. (healthcanal.com)

The Arthritis Foundation is mobilizing patients and their families to engage in studies comparing the effectiveness of treatments for juvenile arthritis and funding research for more options. (arthritis.org)
Dr. R.M. Lakshmanan is currently providing Services/Treatments like Health Checkup (General), Infectious Disease Treatment, Fever Treatment, Insulin Treatment, Stress Management Counselling and many more. (drlogy.com)

Learn the evidence behind popular touch therapies for arthritis, including what to try and what to avoid, for how long and when. (arthritis.org)

Your immune system is a complex network of cells, proteins, tissues and organs that work together to protect you against germs, infectious organisms and disease. (primalblueprint.com)

What Is Lyme Arthritis? (verywellhealth.com)
As many as 300,000 people will become infected with Lyme disease each year , with about 25% of those cases developing Lyme arthritis. (verywellhealth.com)
If you suspect you may be developing Lyme disease-induced arthritis, contact your healthcare provider right away to discuss testing and treatment options. (verywellhealth.com)
Roughly 60% of those with untreated Lyme disease will develop Lyme arthritis. (verywellhealth.com)
Lyme arthritis is the best understood and most studied manifestation of Lyme disease. (lymedisease.org)
In 2015 Dr. Steere wrote: "In our experience, some patients do require longer courses of antibiotic therapy for effective treatment of Lyme arthritis. (lymedisease.org)
Lyme arthritis is not the only consequence of late stage Lyme . (lymedisease.org)

Learn about the National Juvenile Arthritis Conference, a place for families to connect, share and learn. (arthritis.org)

Anatomy49

Organisms12

Diseases51

Chemicals and Drugs81

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Psychiatry and Psychology2

Phenomena and Processes19

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena4

Humanities1

Information Science2

Health Care24

Alpha-toxin and gamma-toxin jointly promote Staphylococcus aureus virulence in murine septic arthritis. (1/959)

Genetic control of experimental lyme arthritis in the absence of specific immunity. (2/959)

Osteonecrosis of the hip in sickle-cell disease associated with tuberculous arthritis. A review of 15 cases. (3/959)

Longitudinal and cross-sectional variability in markers of joint metabolism in patients with knee pain and articular cartilage abnormalities. (4/959)

IL-1beta, IL-6 and TNF-alpha in synovial fluid of patients with non-gonococcal septic arthritis. (5/959)

Slipped capital femoral epiphysis after septic arthritis of the hip in an adolescent: report of a case. (6/959)

Gamma interferon and interleukin-10 gene expression in synovial tissues from patients with early stages of Chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers. (7/959)

Development of lyme arthritis in mice deficient in inducible nitric oxide synthase. (8/959)

Arthritis, Rheumatoid

Arthritis

Arthritis, Experimental

Arthritis, Infectious

Arthritis, Juvenile

Arthritis, Psoriatic

Arthritis, Reactive

Synovial Membrane

Joints

Synovial Fluid

Arthritis, Gouty

Rheumatoid Factor

Mice, Inbred DBA

Synovitis

Osteoarthritis

Collagen Type II

Methotrexate

Severity of Illness Index

Rats, Inbred Lew

Autoantibodies

Blood Sedimentation

Injections, Intra-Articular

Tumor Necrosis Factor-alpha

Rheumatic Diseases

Immunoglobulin G

Arthrography

Rheumatology

Knee Joint

Metacarpophalangeal Joint

Spondylitis, Ankylosing

Sulfasalazine

Peptides, Cyclic

Autoimmune Diseases

Antibodies, Monoclonal

Gold Sodium Thiomalate

Wrist Joint

Rheumatoid Nodule

Collagen

HLA-DRB1 Chains

Finger Joint

Disease Models, Animal

Treatment Outcome

Tarsal Joints

Lyme Disease

Receptors, Tumor Necrosis Factor

HLA-DR4 Antigen

Anti-Inflammatory Agents

Joint Diseases

HLA-DR Antigens

Citrulline

Cytokines

Spondylarthropathies

Foot Joints

Psoriasis

Cartilage, Articular

Ankle Joint

Inflammation

T-Lymphocytes

Interleukin-17

Edema

Freund's Adjuvant

Tarsus, Animal

Enzyme-Linked Immunosorbent Assay

Tenosynovitis

HLA-B27 Antigen

Biological Markers

Organogold Compounds

Drug Therapy, Combination

Hand Joints

Glucose-6-Phosphate Isomerase

Disability Evaluation

Pain

Lupus Erythematosus, Systemic

Cells, Cultured

Interleukin-6

Chronic Disease

Interleukin-1

Genetic Predisposition to Disease

Interleukin 1 Receptor Antagonist Protein

Cartilage