Arthritis infectious. Medical search

A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.

Arthritis caused by BACTERIA; RICKETTSIA; MYCOPLASMA; VIRUSES; FUNGI; or PARASITES.

Arthritis of children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.

A type of inflammatory arthritis associated with PSORIASIS, often involving the axial joints and the peripheral terminal interphalangeal joints. It is characterized by the presence of HLA-B27-associated SPONDYLARTHROPATHY, and the absence of rheumatoid factor.

An aseptic, inflammatory arthritis developing secondary to a primary extra-articular infection, most typically of the GASTROINTESTINAL TRACT or UROGENITAL SYSTEM. The initiating trigger pathogens are usually SHIGELLA; SALMONELLA; YERSINIA; CAMPYLOBACTER; or CHLAMYDIA TRACHOMATIS. Reactive arthritis is strongly associated with HLA-B27 ANTIGEN.

The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.

Also known as articulations, these are points of connection between the ends of certain separate bones, or where the borders of other bones are juxtaposed.

The clear, viscous fluid secreted by the SYNOVIAL MEMBRANE. It contains mucin, albumin, fat, and mineral salts and serves to lubricate joints.

Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The initial attacks are usually monoarticular but later attacks are often polyarticular.

Antibodies found in adult RHEUMATOID ARTHRITIS patients that are directed against GAMMA-CHAIN IMMUNOGLOBULINS.

Inflammation of a synovial membrane. It is usually painful, particularly on motion, and is characterized by a fluctuating swelling due to effusion within a synovial sac. (Dorland, 27th ed)

A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

A fibrillar collagen found predominantly in CARTILAGE and vitreous humor. It consists of three identical alpha1(II) chains.

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.

Measurement of rate of settling of erythrocytes in anticoagulated blood.

Methods of delivering drugs into a joint space.

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.

The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.

Roentgenography of a joint, usually after injection of either positive or negative contrast medium.

A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis.

A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.

The articulation between a metacarpal bone and a phalanx.

A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.

A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)

Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).

Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.

Antibodies produced by a single clone of cells.

A variable mixture of the mono- and disodium salts of gold thiomalic acid used mainly for its anti-inflammatory action in the treatment of rheumatoid arthritis. It is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis.

The joint that is formed by the distal end of the RADIUS, the articular disc of the distal radioulnar joint, and the proximal row of CARPAL BONES; (SCAPHOID BONE; LUNATE BONE; triquetral bone).

Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.

A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).

A subtype of HLA-DRB beta chains that includes over one hundred allele variants. The HLA-DRB1 subtype is associated with several of the HLA-DR SEROLOGICAL SUBTYPES.

The articulation between the head of one phalanx and the base of the one distal to it, in each finger.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

The articulations between the various TARSAL BONES. This does not include the ANKLE JOINT which consists of the articulations between the TIBIA; FIBULA; and TALUS.

An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.

Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells.

An HLA-DR antigen which is associated with HLA-DRB1 CHAINS encoded by DRB1*04 alleles.

Substances that reduce or suppress INFLAMMATION.

A subclass of HLA-D antigens that consist of alpha and beta chains. The inheritance of HLA-DR antigens differs from that of the HLA-DQ ANTIGENS and HLA-DP ANTIGENS.

Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.

Heterogeneous group of arthritic diseases sharing clinical and radiologic features. They are associated with the HLA-B27 ANTIGEN and some with a triggering infection. Most involve the axial joints in the SPINE, particularly the SACROILIAC JOINT, but can also involve asymmetric peripheral joints. Subsets include ANKYLOSING SPONDYLITIS; REACTIVE ARTHRITIS; PSORIATIC ARTHRITIS; and others.

The articulations extending from the ANKLE distally to the TOES. These include the ANKLE JOINT; TARSAL JOINTS; METATARSOPHALANGEAL JOINT; and TOE JOINT.

A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

A protective layer of firm, flexible cartilage over the articulating ends of bones. It provides a smooth surface for joint movement, protecting the ends of long bones from wear at points of contact.

The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS.

A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

A proinflammatory cytokine produced primarily by T-LYMPHOCYTES or their precursors. Several subtypes of interleukin-17 have been identified, each of which is a product of a unique gene.

Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.

The region in the hindlimb of a quadruped, corresponding to the human ANKLE.

An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*27 allele family.

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

Organic compounds that contain GOLD as an integral part of the molecule. Some are used as ANTIRHEUMATIC AGENTS. The term chrysotherapy derives from an ancient Greek term for gold.

Therapy with two or more separate preparations given for a combined effect.

The articulations extending from the WRIST distally to the FINGERS. These include the WRIST JOINT; CARPAL JOINTS; METACARPOPHALANGEAL JOINT; and FINGER JOINT.

An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.

Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)

A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.

A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.

Component of the NATIONAL INSTITUTES OF HEALTH. It supports research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress. It was established in 1986.

Elements of limited time intervals, contributing to particular results or situations.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.

Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.

3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.

A specific species of bacteria, part of the BORRELIA BURGDORFERI GROUP, whose common name is Lyme disease spirochete.

A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.

Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)

Infections with bacteria of the genus YERSINIA.

Pain in the joint.

Inflammation of the joints of the SPINE, the intervertebral articulations.

Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by AUTOIMMUNE DISEASES.

Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.

The articulation between the head of one phalanx and the base of the one distal to it, in each toe.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.

A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.

Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.

The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.

A plasma protein that circulates in increased amounts during inflammation and after tissue damage.

Deformities of the hand, or a part of the hand, acquired after birth as the result of injury or disease.

Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.

Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.

Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.

Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.

Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.

Bone loss due to osteoclastic activity.

An extracellular endopeptidase of vertebrate tissues similar to MATRIX METALLOPROTEINASE 1. It digests PROTEOGLYCAN; FIBRONECTIN; COLLAGEN types III, IV, V, and IX, and activates procollagenase. (Enzyme Nomenclature, 1992)

An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

A rare complication of rheumatoid arthritis with autoimmune NEUTROPENIA; and SPLENOMEGALY.

The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.

The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.

Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

A double gliding joint formed by the CLAVICLE, superior and lateral parts of the manubrium sterni at the clavicular notch, and the cartilage of the first rib.

The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).

The articulation between a metatarsal bone (METATARSAL BONES) and a phalanx.

An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact mechanism of action is unknown, but it is believed to act via immunological mechanisms and alteration of lysosomal enzyme activity. Its efficacy is slightly less than that of injected gold salts, but it is better tolerated, and side effects which occur are potentially less serious.

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.

Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.

The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.

Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.

Inflammation of the bone.

A species of LENTIVIRUS, subgenus ovine-caprine lentiviruses (LENTIVIRUSES, OVINE-CAPRINE), closely related to VISNA-MAEDI VIRUS and causing acute encephalomyelitis; chronic arthritis; PNEUMONIA; MASTITIS; and GLOMERULONEPHRITIS in goats. It is transmitted mainly in the colostrum and milk.

Treatment of diseases with biological materials or biological response modifiers, such as the use of GENES; CELLS; TISSUES; organs; SERUM; VACCINES; and humoral agents.

Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.

A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)

A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.

The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.

Sites on an antigen that interact with specific antibodies.

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.

Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.

Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.

The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Methods to determine in patients the nature of a disease or disorder at its early stage of progression. Generally, early diagnosis improves PROGNOSIS and TREATMENT OUTCOME.

Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Subset of helper-effector T-lymphocytes which synthesize and secrete IL-17, IL-17F, and IL-22. These cytokines are involved in host defenses and tissue inflammation in autoimmune diseases.

The performance of the basic activities of self care, such as dressing, ambulation, or eating.

A thioglucose derivative used as an antirheumatic and experimentally to produce obesity in animals.

Diseases of BONES.

A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases.

Gram-negative helical bacteria, in the genus BORRELIA, that are the etiologic agents of LYME DISEASE. The group comprises many specific species including Borrelia afzelii, Borellia garinii, and BORRELIA BURGDORFERI proper. These spirochetes are generally transmitted by several species of ixodid ticks.

Glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.

Glycoproteins which have a very high polysaccharide content.

An encapsulated lymphatic organ through which venous blood filters.

The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed)

The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.

Partial or total replacement of a joint.

A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.

Biologically active substances whose activities affect or play a role in the functioning of the immune system.

Combinations of diagnostic or therapeutic substances linked with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; or ANTIGENS. Often the diagnostic or therapeutic substance is a radionuclide. These conjugates are useful tools for specific targeting of DRUGS and RADIOISOTOPES in the CHEMOTHERAPY and RADIOIMMUNOTHERAPY of certain cancers.

Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)

Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.

Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.

In horses, cattle, and other quadrupeds, the joint between the femur and the tibia, corresponding to the human knee.

Surgical reconstruction of a joint to relieve pain or restore motion.

Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

Tuberculosis of the bones or joints.

A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.

The relationship between the dose of an administered drug and the response of the organism to the drug.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Distortion or disfigurement of the foot, or a part of the foot, acquired through disease or injury after birth.

The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.

A hinge joint connecting the FOREARM to the ARM.

A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.

The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.

Specific molecular sites on the surface of various cells, including B-lymphocytes and macrophages, that combine with IMMUNOGLOBULIN Gs. Three subclasses exist: Fc gamma RI (the CD64 antigen, a low affinity receptor), Fc gamma RII (the CD32 antigen, a high affinity receptor), and Fc gamma RIII (the CD16 antigen, a low affinity receptor).

Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)

The joint involving the CERVICAL ATLAS and axis bones.

PROTEOGLYCANS-associated proteins that are major components of EXTRACELLULAR MATRIX of various tissues including CARTILAGE; and INTERVERTEBRAL DISC structures. They bind COLLAGEN fibers and contain protein domains that enable oligomer formation and interaction with other extracellular matrix proteins such as CARTILAGE OLIGOMERIC MATRIX PROTEIN.

The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.

A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.

Antibodies which react with the individual structural determinants (idiotopes) on the variable region of other antibodies.

The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.

A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.

Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

Endoscopic examination, therapy and surgery of the joint.

Presence of calcium salts, especially calcium pyrophosphate, in the cartilaginous structures of one or more joints. When accompanied by attacks of goutlike symptoms, it is called pseudogout. (Dorland, 27th ed)

A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components.

A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.

Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules.

The immovable joint formed by the lateral surfaces of the SACRUM and ILIUM.

The CARPAL BONES; METACARPAL BONES; and FINGER PHALANGES. In each hand there are eight carpal bones, five metacarpal bones, and 14 phalanges.

A class of compounds composed of repeating 5-carbon units of HEMITERPENES.

Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They form into aggregates that provide tissues with the capacity to resist high compressive and tensile forces.

The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.

A fluid-filled sac lined with SYNOVIAL MEMBRANE that provides a cushion between bones, tendons and/or muscles around a joint.

Disease having a short and relatively severe course.

Alpha-toxin and gamma-toxin jointly promote Staphylococcus aureus virulence in murine septic arthritis. (1/959)

Septic arthritis is a common and feared complication of staphylococcal infections. Staphylococcus aureus produces a number of potential virulence factors including certain adhesins and enterotoxins. In this study we have assessed the roles of cytolytic toxins in the development of septic arthritis by inoculating mice with S. aureus wild-type strain 8325-4 or isogenic mutants differing in the expression of alpha-, beta-, and gamma-toxin production patterns. Mice inoculated with either an alpha- or beta-toxin mutant showed degrees of inflammation, joint damage, and weight decrease similar to wild-type-inoculated mice. In contrast, mice inoculated with either double (alpha- and gamma-toxin-deficient)- or triple (alpha-, beta-, and gamma-toxin-deficient)-mutant S. aureus strains showed lower frequency and severity of arthritis, measured both clinically and histologically, than mice inoculated with the wild-type strain. We conclude that simultaneous production of alpha- and gamma-toxin is a virulence factor in S. aureus arthritis. (+info)

Genetic control of experimental lyme arthritis in the absence of specific immunity. (2/959)

Host genetics play an important role in determining resistance or susceptibility to experimental Lyme arthritis. While specific immunity appears to regulate disease resolution, innate immunity appears to regulate disease severity. Intradermal infection with Borrelia burgdorferi yields severe arthritis in C3H/He (C3H) mice but only minimal arthritis in BALB/c mice. Intradermal infection of immunodeficient C3H SCID mice also results in severe arthritis, but arthritis of only moderate severity in BALB/c SCID mice. In the present study, we examined immunodeficient recombinase-activating gene-knockout (RAG-1(-/-)) (RAG-) mice from resistant C57BL/6 (B6) and DBA/2 (DBA) mouse strains. B. burgdorferi-infected B6 RAG- and DBA RAG- mice had little or no ankle swelling, a low occurrence of inflammatory infiltrates in tibiotarsal joints, and low arthritis severity scores in comparison to RAG+ and RAG- BALB/c or C3H mice. Few differences in spirochete DNA levels in ankles of resistant and susceptible RAG- mice were seen. These data suggest that resistance to arthritis development following B. burgdorferi infection is not necessarily dependent on an acquired immune response and can occur despite the presence of high spirochete burden. Thus, genes expressed outside the specific immune response can be central regulators of experimental arthritis. (+info)

Osteonecrosis of the hip in sickle-cell disease associated with tuberculous arthritis. A review of 15 cases. (3/959)

We report a study of 15 cases of tuberculous hips with sickle-cell disease who presented during 1991-1993. Although the osteonecrosis was long-standing, biopsy was nearly always required to reveal the more recent tuberculous infection. Management consisted of 6 months of anti-tuberculous chemotherapy with appropriate palliative surgery 5-8 weeks after the start of drug treatment. The operative techniques which we used are described. The results were good both post-operatively, and in 12 patients followed-up at an average of 3 years. We recommend this combined management for the treatment of secondary tuberculous infections of hips previously damaged by sickle-cell disease. (+info)

Longitudinal and cross-sectional variability in markers of joint metabolism in patients with knee pain and articular cartilage abnormalities. (4/959)

OBJECTIVE: To determine the within- and between-patient variability in the concentrations of synovial fluid, serum and urine markers of joint tissue metabolism in a cohort of patients with knee pain and cartilage changes consistent with early-stage knee osteoarthritis. DESIGN: Samples of synovial fluid, serum, and urine were obtained from 52 patients on eight different occasions during 1 year, as part of a clinical trial in patients with cartilage abnormalities and knee pain. In joint fluid, aggrecan fragments were quantified by dye precipitation and enzyme-linked immunosorbent assay (ELISA), and matrix metalloproteinases-1 and -3, and tissue inhibitor of metalloproteinases-1 by sandwich ELISAs. In serum, keratan sulfate was quantified by ELISA. Type I collagen N-telopeptide cross-links in urine were determined by ELISA. RESULTS: The degree of cross-sectional variability in marker concentrations did not vary between the different sampling occasions, and did not differ between the periods of weeks 0 (baseline), 1-4 (treatment) and 13-26 (follow-up). Both between-patient and within-patient coefficients of variation varied for markers in different body fluid compartments, with the lowest variability for serum keratan sulfate, followed by urine type I collagen N-telopeptide crosslinks, and the highest for synovial fluid markers. For synovial fluid, aggrecan fragments showed the least variability, and matrix metalloproteinases the highest. One patient with septic arthritis showed a fivefold peak increase in joint fluid aggrecan fragment concentrations, while the concentration of matrix metalloproteinase-3 increased 100-fold. CONCLUSIONS: Molecular markers of joint tissue metabolism have been suggested as, for example, outcome measures for clinical trials of disease-modifying drugs in osteoarthritis. This report is the first to present data on between- and within-patient variability for such molecular markers in three different body fluid compartments in stable cohort of patients. The availability of such data enables calculations to determine the number of patients needed in prospective studies using these markers as outcome measures. (+info)

IL-1beta, IL-6 and TNF-alpha in synovial fluid of patients with non-gonococcal septic arthritis. (5/959)

Interleukin-1 beta (IL-1beta), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are the main proinflammatory cytokines responsible for the inflammatory process and cartilage destruction of inflammatory arthropathies. The present study sequentially measured the concentrations of these cytokines and their proportions of detectable levels in the synovial fluid (SF) of 23 patients with non-gonococcal (GC) septic arthritis before and after treatment. Persistently high concentrations and proportions of IL-6 and TNF-alpha were found up to day 7 of treatment, while SF IL-1beta concentration declined significantly after day 7 (p = 0.036). SF IL-1beta and TNF-alpha correlated with each other significantly and with SF WBC counts (p < 0.01). Positive correlations between SF IL-1beta concentration and joint effusion (p < 0.01) and between SF TNF-alpha concentration and joint tenderness (p < 0.001) were observed. SF IL-1beta and TNF-alpha were significantly higher in patients with local complications of septic arthritis. In conclusion, high levels of IL-1beta, IL-6 and TNF-alpha were detected in SF of patients with non-GC septic arthritis. Only IL-1beta decreased significantly after day 7 of treatment, but IL-6 and TNF-alpha concentrations were persistently high. SF IL-1beta and TNF-alpha may be useful in predicting the outcome and complications of patients with this disease. (+info)

Slipped capital femoral epiphysis after septic arthritis of the hip in an adolescent: report of a case. (6/959)

Septic arthritis of the hip must be managed promptly to avoid the serious complications associated with the condition. In the case reported here, the diagnosis was delayed and was complicated by a slipped capital femoral epiphysis. The patient, an adolescent boy previously in good health, presented with a 2-week history of hip pain and systemic illness. Septic arthritis was diagnosed and was managed by incision and drainage and antibiotic therapy. Two weeks later he presented with a subcutaneous abscess and a slipped capital femoral epiphysis, which was pinned in situ. There was a 2.5-cm leg-length discrepancy. Avascular necrosis of the femoral head subsequently developed leaving the boy with a permanent disability. (+info)

Gamma interferon and interleukin-10 gene expression in synovial tissues from patients with early stages of Chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers. (7/959)

Genetically determined differences in interleukin-10 (IL-10) and gamma interferon (IFN-gamma) responses in mice correlate with clearance of Chlamydia pneumonitis infection. We measured the synovial expression of IL-10 and IFN-gamma and additional cytokine genes in patients who had recent-onset Chlamydia-associated arthritis (Chl-AA). IL-10 and IFN-gamma mRNA were relatively abundant in recent-onset Chl-AA. (+info)

Development of lyme arthritis in mice deficient in inducible nitric oxide synthase. (8/959)

Nitric oxide (NO) is a powerful antimicrobial agent and an important regulatory molecule of the innate immune response. To determine if NO has a role in experimental Lyme disease, arthritis-resistant DBA/2J and arthritis-susceptible C3H/HeJ mice were bred to be genetically deficient for inducible NO synthase (iNOS). Following footpad injection of Borrelia burgdorferi, arthritis was similar between iNOS-deficient and control animals regardless of their genetic background. Histologic examination and arthritis severity scores of ankles revealed no differences in arthritis development between iNOS-deficient and control animals. Despite being deficient in a key antimicrobial agent, iNOS-deficient mice had tissue levels of B. burgdorferi similar to those in control mice. Thus, NO does not have a critical role in susceptibility to Lyme arthritis through tissue damage via an overexuberant inflammatory response, nor is it required in resistance through the clearance of spirochetes from tissues. (+info)

When microbes were first recognized as the cause of infectious diseases, it was immediately clear that multicellular organisms ... Sallusto F, Lanzavecchia A (2002). "The instructive role of dendritic cells on T-cell responses". Arthritis Research. 4 Suppl 3 ... Clinical Infectious Diseases. 41 Suppl 7: S421-6. doi:10.1086/431992. PMID 16237641. ...

https://en.wikipedia.org/wiki/Toll-like_receptor

Schmitt, SK (June 2017). "Reactive Arthritis". Infectious Disease Clinics of North America (Review). 31 (2): 265-77. doi: ... It is associated with HLA B27 arthropathies, such as ankylosing spondylitis, psoriatic arthritis, and reactive arthritis. ... "Tendinitis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 12 April 2017. Retrieved 18 November 2018. ... thought to often precede psoriatic arthritis). A common autoimmune enthesitis is at the heel, where the Achilles tendon ...

https://en.wikipedia.org/wiki/Enthesitis

Schmitt, SK (June 2017). "Reactive Arthritis". Infectious Disease Clinics of North America (Review). 31 (2): 265-277. doi: ... It is associated with HLA B27 arthropathies such as ankylosing spondylitis, psoriatic arthritis, and reactive arthritis. ... Less common causes include infection, arthritis, gout, thyroid disease, and diabetes. Despite the injury of the tendon there is ... Less common causes include infection, arthritis, gout, thyroid disease, and diabetes. Diagnosis is typically based on symptoms ...

https://en.wikipedia.org/wiki/Tendinopathy

... the Paul Bunn Award in Infectious Disease; the Lee C. Howley Prize in Arthritis Research; and the Irish Society for Immunology ... He started his own group in the National Cancer Institute in 1989, and then moved to the National Institute of Arthritis and ... in 1981 for subspecialty training in allergy and immunology in the National Institute of Allergy and Infectious Diseases. He ... FoxP3+ regulatory T cells confer infectious tolerance in a TGF- -dependent manner". Journal of Experimental Medicine. 205 (9): ...

https://en.wikipedia.org/wiki/John_J._O'Shea

Melendez PR, Johnson RH (1991). "Bacteremia and septic arthritis caused by Moraxella catarrhalis". Reviews of Infectious ... This was also the second case of M. catarrhalis causing septic arthritis (although in the first case, no mention of bacteremia ... During the first reported case of M. catarrhalis causing bacteremia that was associated with septic arthritis, the microbe was ... M. catarrhalis has also been linked with septic arthritis in conjunction with bacteremia. Although cases of bacteremia caused ...

https://en.wikipedia.org/wiki/Moraxella_catarrhalis

"Candida Arthritis: Analysis of 112 Pediatric and Adult Cases". Open Forum Infectious Diseases. 3 (1): ofv207. doi:10.1093/ofid/ ...

https://en.wikipedia.org/wiki/Candida_(fungus)

Dendle, C.; Woolley, I. J.; Korman, T. M. (December 2006). "Rat-bite fever septic arthritis: illustrative case and literature ... International Journal of Infectious Diseases. 5 (3): 151-154. doi:10.1016/s1201-9712(01)90090-6. ISSN 1201-9712. PMID 11724672 ... Symptoms of RBF include sudden high temperature fevers with rigors, vomiting, headaches, painful joints/arthritis. A red, bumpy ... and arthritis of large joints can be seen. The organism can be cultivated in blood or articular fluid. The disease can be fatal ...

https://en.wikipedia.org/wiki/Rat-bite_fever

Meanwhile, by way of continuing case reports claiming cures of chronic diseases like arthritis after extraction of infected or ... Fish theorized that by removing the infectious nidus, dentists would permit recovery from the infection, and Fish's reasoning ... In ancient Greece, Hippocrates reported cure of an arthritis case by tooth extraction. Yet modern focal infection theory ... In 1938, Cecil and Angevine reported 200 cases of rheumatoid arthritis, but no consistent cures by tonsillectomies or tooth ...

https://en.wikipedia.org/wiki/Focal_infection_theory

Patients are usually no longer infectious once the rash has appeared. Teenagers and adults may present with a self-limited ... It manifests in painful swelling of the joints that feels similar to arthritis. Older children and adults with fifth disease ... Individuals with fifth disease are most infectious before the onset of symptoms. Typically, school children, day-care workers, ...

https://en.wikipedia.org/wiki/Fifth_disease

"Infectious bovine keratoconjunctivitis" (IBK) is a disease affecting cattle caused by the bacteria Moraxella bovis. "Pink eye ... "Sicca" means "dryness" in medical contexts.) It occurs with 20% of rheumatoid arthritis patients. The term "vernal ... in sheep and goat" is another infectious keratoconjunctivitis of veterinary concern, mostly caused by Chlamydophila pecorum. " ...

https://en.wikipedia.org/wiki/Keratoconjunctivitis

... is a mosquito-borne infectious disease caused by infection with the Ross River virus. The illness is typically ... Mice infected with RRV develop hind-limb arthritis/arthralgia which is similar to human disease. The disease in mice is ... Before the identification of this infectious agent, the disease was referred to as "epidemic polyarthritis". This term was also ... Symptoms of the disease vary widely in severity, but major indicators are arthralgia, arthritis, fever, and rash. The ...

https://en.wikipedia.org/wiki/Ross_River_fever

The differential for this finding includes malignant and inflammatory etiologies, either infectious or sterile. This includes ... It also includes lung manifestations of autoimmune diseases such as Sjögren syndrome or rheumatoid arthritis. Histopathologic ...

https://en.wikipedia.org/wiki/Tree-in-bud_sign

Several different animal species are susceptible to infection by S. dysgalactiae, but bovine mastitis and infectious arthritis ... "Sources of Streptococcus dysgalactiae in English and Welsh sheep flocks affected by infectious arthritis (joint ill)". The ... The first pivotal step in infectious pathogenesis is the attachment to the host tissues. The M-protein, the most extensively ... S. dysgalactiae has been isolated from infectious polyarthritis in several animal species, including piglets, lambs, calves and ...

https://en.wikipedia.org/wiki/Streptococcus_dysgalactiae

Clinical Infectious Diseases. 62 (4): 491-3. doi:10.1093/cid/civ875. PMID 26449564. Working with Marine Mammals and Your Health ... "Identification of a Novel Mycoplasma Species in a Patient With Septic Arthritis of the Hip and Seal Finger". ... Clinical Infectious Diseases. 27 (5): 1168-70. doi:10.1086/514980. JSTOR 4481672. PMID 9827264. Westley, Benjamin P.; ...

https://en.wikipedia.org/wiki/Seal_finger

... see infectious arthritis). Common noninfectious tenosynovitis are: stenosing tenosynovitis, intersection syndrome, extensor ... Infectious tenosynovitis is the infection of closed synovial sheaths in the flexor tendons of the fingers. It is usually caused ... Most infectious tenosynovitis cases should be managed with tendon sheath irrigation and drainage, with or without debridement ... "Infectious Tenosynovitis". Uptodate. Avira M, Giladi; Sunitha, Malay; Kevin, C Chung (23 March 2016). "Management of acute ...

https://en.wikipedia.org/wiki/Tenosynovitis

Rarely, the major complaint may be arthritis. Shunt nephritis occurs when a shunt becomes infected with bacteria, most commonly ... Management is focused on removing the infectious source. The shunt is removed immediately and antibiotics are begun. The ... Legoupil N, Ronco P, Berenbaum F (May 2003). "Arthritis-related shunt nephritis in an adult". Rheumatology (Oxford). 42 (5): ... Approximately 12% of ventriculoatrial shunts become infected, with Staphylococcus epidermidis being the infectious agent in 75 ...

https://en.wikipedia.org/wiki/Shunt_nephritis

... including cancer and arthritis. Cell adhesion is also essential for infectious organisms, such as bacteria or viruses, to cause ... Arthritis Research. 2 (5): 368-373. doi:10.1186/ar114. PMC 130138. PMID 11094450. Pizarro-Cerdá, Javier; Cossart, Pascale (2006 ...

https://en.wikipedia.org/wiki/Cell_adhesion

Infectious diseases that affect dogs are important not only from a veterinary standpoint, but also because of the risk to ... Over time it often causes arthritis in the hips. Dysplasia can also occur in the elbow joint. Luxating patellas can be a ... An infectious disease is caused by the presence of organisms such as viruses, bacteria, fungi, or parasites (either animalian ... Certain infectious diseases are a concern from a public health standpoint because they are zoonoses (transmittable to humans). ...

https://en.wikipedia.org/wiki/Dog_health

Infectious diseases: hepatitis B, hepatitis C, human immunodeficiency virus (HIV), cytomegalovirus, lyme disease, human T-cell- ... Some examples of such illness which can cause vasculitic neuropathy are: Connective tissue diseases: rheumatoid arthritis, ...

https://en.wikipedia.org/wiki/Vasculitic_neuropathy

Rheumatoid arthritis. Confusion with rheumatoid arthritis may be common even though IH is a non-inflammatory condition without ... Links to other infectious disease have also been posited over the years. These included Brucella, gonorrhoea, and syphilis. ... Atlanta: Arthritis Foundation, 1997: 127-9. Setti G, Calciolari CA, Cimino V, et al. The treatment of idiopathic and secondary ... Mattingly suggests that IH may be an unusual variant of rheumatoid arthritis, and some patients may go on to develop RA. Joint ...

https://en.wikipedia.org/wiki/Intermittent_hydrarthrosis

Septic arthritis, a severe infection of the joint that can lead to permanent joint damage. Spondyloarthropathies. Viral ... Infectious, such as Lyme disease and osteomyelitis. Neurological, such as spinal cord injury and vertebral degeneration. ... Juvenile idiopathic arthritis. Lyme disease, which is transmitted by ticks and is characterized by debilatating polyarthritis, ... Rheumatic, such as ankylosing spondylitis, rheumatoid arthritis, gout. Others, such as fractures, osteoarthritis, Paget's ...

https://en.wikipedia.org/wiki/Bone_pain

Cooke GS, Hill AV (December 2001). "Genetics of susceptibility to human infectious disease". Nature Reviews. Genetics. 2 (12): ... Researchers speculate that HLA-B27 may abnormally display to the immune system peptides that trigger arthritis. Other research ... Following an infection, affected individuals may develop arthritis, back pain, and eye inflammation. Like ankylosing ... reactive arthritis, is typically triggered by bacterial infections of the gastrointestinal or genital tract. ...

https://en.wikipedia.org/wiki/HLA-B

Psoriatic arthritis[edit]. In 2003, adalimumab began undergoing trials for use in treating psoriasis and psoriatic arthritis.[ ... Non-infectious uveitis[edit]. Adalimumab is indicated for the treatment of non-infectious uveitis (inflammation of the layer ... polyarticular juvenile idiopathic arthritis and active enthesitis-related arthritis (both rare diseases causing inflammation in ... Since 2008, adalimumab had been approved by the FDA for the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing ...

https://en.wikipedia.org/wiki/Adalimumab?fbclid=IwAR0kN6_SAsvpklfBrX1eex9_OYvtp-Oxig3N-LuJPcx5MvcJhmzA9_Cv2ko

Research on T-cell vaccination so far has focused mostly on multiple sclerosis and to a lesser extent on rheumatoid arthritis, ... The concept of T-cell vaccination is, at least partially, analogous to classical vaccination against infectious disease. ...

https://en.wikipedia.org/wiki/T-cell_vaccination

... rheumatoid arthritis, and infectious diseases. In December 2007, Eisai acquired MGI Pharma, a company specializing in oncology ...

https://en.wikipedia.org/wiki/Eisai_(company)

Other infectious causes include a lung abscess, pneumonia (including pneumocystis pneumonia) or rarely nocardial infection or ... such as rheumatoid arthritis or granulomatosis with polyangiitis, or organizing pneumonia. A solitary lung nodule can be found ... inflammatory or infectious, for example) will also show up on a PET scan. If the nodule has a diameter of less than one ...

https://en.wikipedia.org/wiki/Lung_nodule

National Institute of Allergy and Infectious Diseases (NIAID). *National Institute of Arthritis and Musculoskeletal and Skin ... The National Institute of Allergy and Infectious Diseases maintains its Rocky Mountain Labs in Hamilton, Montana,[23] with an ... National Institute of Arthritis and Musculoskeletal and Skin Diseases. *National Institute of Biomedical Imaging and ... With this hopefully more pain management will be available including techniques for arthritis sufferers.[30] ...

https://en.wikipedia.org/wiki/National_Institute_of_Health

Avian arthritis causes significant lameness in joints, specifically the hock joints. In the most severe cases, viral arthritis ... Infectious agents, which increase the pathogenicity of reovirus in the joints of chicken, include Mycoplasma synoviae, ... Infection causes arthritis and tenosynovitis in poultry. It can also cause respiratory disease. Avian orthoreovirus infection ... Chicks that are infected one day after birth are more prone to experimentally synthesized tenosynovitis/arthritis than those ...

https://en.wikipedia.org/wiki/Avian_orthoreovirus

... is an infectious disease caused by the gram negative bacillus Yersinia pseudotuberculosis. In Japan ... knees skin desquamation exanthema red tongue toxic shock syndrome Other features include mesenteric lymphadenitis and arthritis ...

https://en.wikipedia.org/wiki/Far_East_scarlet-like_fever

The Journal of Infectious Diseases. 184 (5): 582-90. doi:10.1086/322803. ISSN 0022-1899. JSTOR 30137322. PMID 11474432.. ... septic arthritis, endocarditis, peritonitis, pericarditis, cellulitis, and brain abscess.[6] ... Diagnostic Microbiology and Infectious Disease. 90 (4): 248-250. doi:10.1016/j.diagmicrobio.2017.12.003. ISSN 1879-0070. PMID ... The Pediatric Infectious Disease Journal. 20 (12): 1144-9. doi:10.1097/00006454-200112000-00010. PMID 11740321.. ...

https://en.wikipedia.org/wiki/S._pneumoniae

Infectious Diseases (Systematic Review). 16 (3): e23-33. doi:10.1016/S1473-3099(15)00527-7. PMID 26852728. Archived (PDF) from ... "National Institute of Arthritis and Musculoskeletal and Skin Diseases. May 2013. Archived from the original on 2 February 2015. ... Questions and Answers about Acne - US National Institute of Arthritis and Musculoskeletal and Skin Diseases ...

https://en.wikipedia.org/wiki/Acne_vulgaris

Infectious. *Septic arthritis. *Tuberculosis arthritis. Crystal. *Chondrocalcinosis. *CPPD (Psudogout). *Gout. Seronegative. * ...

https://en.wikipedia.org/wiki/Osteochondroprogenitor_cell

Lyme disease or borreliosis, is an infectious disease. It is caused by bacteria of the genus Borrelia. The disease is carried ... Arthritis. *Fatigue. *Headache. *Myalgias (muscle pain) and arthralgias (joint pain). *Stiff neck ...

https://simple.wikipedia.org/wiki/Lyme_disease

"Study finds bacteria in milk linked to rheumatoid arthritis". MedicalXpress. University of Central Florida. 30 January 2018. ... The Lancet Infectious Diseases. 7 (9): 607-613. doi:10.1016/S1473-3099(07)70211-6. PMID 17714674.. ... and suspected causative agent in human Crohn's disease and rheumatoid arthritis.[2] The type strain is ATCC 19698 (equivalent ...

https://en.wikipedia.org/wiki/Mycobacterium_avium_subspecies_paratuberculosis

Chronic inflammation - especially juvenile rheumatoid arthritis, rheumatoid arthritis, Still's disease, Crohn's disease, ... Infectious diseases - viral (AIDS, SARS, West Nile encephalitis, hepatitis, herpes, measles, others), bacterial (TB, typhoid, ... Immune dysfunction - arthritis, systemic lupus erythematosus, Sjögren syndrome, myasthenia gravis, systemic vasculitis, Behcet- ... Immune dysfunction - disorders of collagen, AIDS, rheumatoid arthritis. *Blood cell dysfunction - megaloblastic anemia, ...

https://en.wikipedia.org/wiki/Immune_cell

Equine infectious anemia. *Bovine immunodeficiency virus (BIV). *Caprine arthritis encephalitis virus. *Visna virus ... These are infectious RNA- or DNA-containing viruses which are transmitted from individual to individual. ... Thus it is the Env protein that enables the retrovirus to be infectious. ...

https://en.wikipedia.org/wiki/SsRNA-RT_virus

These infectious agents produce proteases and collagenases which break down the corneal stroma. Complete loss of the stroma can ... These include Rheumatoid arthritis, rosacea, systemic sclerosis which lead to a special type of corneal ulcer called Mooren's ... In ophthalmology, a corneal ulcer usually refers to having an infectious cause while the term corneal abrasion refers more to ... Topical antibiotics are used at hourly intervals to treat infectious corneal ulcers. Cycloplegic eye drops are applied to give ...

https://en.m.wikipedia.org/wiki/Corneal_ulcer

... helps remove infectious agents.[2] Also, mucus traps infectious agents.[2] The gut flora can prevent the colonization of ... swelling of affected tissues, such as the upper throat during the common cold or joints affected by rheumatoid arthritis; ... Acting as a physical and chemical barrier to infectious agents; via physical measures like skin or tree bark and chemical ... The epithelial surfaces form a physical barrier that is impermeable to most infectious agents, acting as the first line of ...

https://en.wikipedia.org/wiki/Innate_immune_system

In microbiology, xenophagy is the autophagic degradation of infectious particles. Cellular autophagic machinery also play an ... "Arthritis Rheum. 62 (3): 791-801. doi:10.1002/art.27305. PMC 2838960 . PMID 20187128.. ... "Arthritis Rheum. 64 (4): 1182-1192. doi:10.1002/art.33444. PMC 3288456 . PMID 22034068.. ... "Arthritis Rheumatol. 67 (6): 1568-1576. doi:10.1002/art.39073. PMC 4446178 . PMID 25708836.. ...

https://en.wikipedia.org/wiki/Autophagy_

Virchow, RL (1966) [1866]. "Rudolph Virchow on ochronosis.1866". Arthritis and Rheumatism. 9 (1): 66-71. doi:10.1002/art. ... He was the first to establish a link between infectious diseases between humans and animals, for which he coined the term " ... Benedek, Thomas G. (1966). "Rudolph virchow on ochronosis". Arthritis & Rheumatism. 9 (1): 66-71. doi:10.1002/art.1780090108. ...

https://en.m.wikipedia.org/wiki/Rudolf_Virchow

The Journal of Infectious Diseases. 148 (5): 785-794. doi:10.1093/infdis/148.5.785. ISSN 0022-1899. PMID 6605395.. .mw-parser- ...

https://en.wikipedia.org/wiki/Antibody-dependent_cellular_cytotoxicity

National Institute of Allergy and Infectious Diseases (July 2012). "Food Allergy An Overview" (PDF). Archived from the original ... National Institute of Allergy and Infectious Diseases (July 2004). "Food Allergy: An Overview" (PDF). National Institutes of ...

https://en.wikipedia.org/wiki/Food_allergy

Chronic arthritis[edit]. In those who have more than two weeks of arthritis, ribavirin may be useful.[4] The effect of ... "Current Infectious Disease Reports. 13 (3): 218-28. doi:10.1007/s11908-011-0180-1. PMC 3085104. PMID 21465340.. ... "Arthritis Research & Therapy. 15 (1): R9. doi:10.1186/ar4137. PMC 3672753. PMID 23302155.. ... "Emerging Infectious Diseases. 14 (3): 412-5. doi:10.3201/eid1403.070720. PMC 2570824. PMID 18325255.. ...

https://en.wikipedia.org/wiki/Chikungunya_vaccine

Discovery of anti-TNF therapy as an effective treatment for rheumatoid arthritis and other autoimmune diseases.[47] ... many of whom are now distinguished leaders in the fields of microbiology and infectious diseases.[2] ...

https://en.wikipedia.org/wiki/Lasker_Foundation

National Institute of Allergy and Infectious Diseases. *National Institute of Arthritis and Musculoskeletal and Skin Diseases ...

https://en.wikipedia.org/wiki/Harold_Varmus

The spasticity can and usually does lead to a very early onset of muscle stress symptoms like arthritis and tendinitis, ... Osler also suspected polioencephalitis as an infectious cause. Through the 1890s, scientists commonly confused CP with polio.[6 ... Intrauterine and neonatal insults (many of which are infectious) increase the risk.[63] ...

https://en.wikipedia.org/wiki/Cerebral_palsy

... individuals who have not yet healed after this point will rarely gain full function in their arm and may develop arthritis. ... Infectious. *Vertically transmitted infection. *Neonatal infection *Congenital rubella syndrome. *Neonatal herpes simplex ...

https://en.wikipedia.org/wiki/Erbs_Palsy

The most common infectious causes are viral followed by bacterial.[2] The viral infection may occur along with other symptoms ... Reactive arthritis is highly associated with HLA-B27. Conjunctivitis is associated with the autoimmune disease relapsing ... Conjunctivitis is part of the triad of reactive arthritis, which is thought to be caused by autoimmune cross-reactivity ... Some more serious conditions can present with a red eye, such as infectious keratitis, angle-closure glaucoma, or iritis. These ...

https://en.wikipedia.org/wiki/Pink_Eye

"The lag time between onset of symptoms and diagnosis of rheumatoid arthritis". Arthritis and Rheumatism. 37 (6): 814-820. doi: ... For instance, a proper diagnosis of infectious diseases usually requires both an examination of signs and symptoms, as well as ...

https://en.wikipedia.org/wiki/Diagnosis_

"Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation". Nature ... and Infectious disease.[68][69] ...

https://en.wikipedia.org/wiki/Single_cell_sequencing?source=post_page---------------------------

Squalene has caused rheumatoid arthritis in rats already prone to arthritis.[28] ... 1987). Immunopharmacology of infectious diseases: vaccine adjuvants and modulators of non-specific resistance. Progress in ... "The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats". The American Journal of Pathology ...

https://en.wikipedia.org/wiki/Immunologic_adjuvant

... systemic sclerosis juvenile idiopathic arthritis, and psoriatic arthritis.[12][clarification needed] ... In areas where multiple infectious diseases are endemic, autoimmune diseases are quite rarely seen. The reverse, to some extent ... Thus, in rheumatoid arthritis there are autoantibodies to IgG Fc but apparently no corresponding T cell response. In systemic ... Systemic autoimmune diseases include SLE, Sjögren's syndrome, sarcoidosis, scleroderma, rheumatoid arthritis, cryoglobulinemic ...

https://en.wikipedia.org/wiki/Autoimmune

Infectious disease Lemierre's syndrome refers to infectious thrombophlebitis of the internal jugular vein.[1] It most often ... Beldman TF, Teunisse HA, Schouten TJ (November 1997). "Septic arthritis of the hip by Fusobacterium necrophorum after ... Hagelskjaer Kristensen L, Prag J (Aug 2000). "Human necrobacillosis, with emphasis on Lemierre's syndrome". Clinical Infectious ...

https://en.wikipedia.org/wiki/Lemierre's_syndrome

"Center for Infectious Disease Research & Policy. Retrieved 27 December 2007.. *^ LeDuc JW, Jahrling PB (2001). "Strengthening ... Swollen joints limit movement, and arthritis may lead to limb deformities, ankylosis, malformed bones, flail joints, and stubby ... "Emerging Infectious Diseases. 17 (4): 676-680. doi:10.3201/eid1704.101960. ISSN 1080-6040. PMC 3377426. PMID 21470458.. ... Smallpox was an infectious disease caused by one of two virus variants, Variola major and Variola minor.[7] The last naturally ...

https://en.wikipedia.org/wiki/Smallpox

Cohen, Jonathan; Powderly, William (2004). Infectious Diseases, 2nd ed. Mosby (Elsevier). Chapter 33: Bronchitis, ...

https://en.wikipedia.org/wiki/Bronchitus

Shaw, Susan E.; Day, Michael J. (11 April 2005). Arthropod-borne Infectious Diseases of the Dog and Cat. Manson Publishing. p. ... Arthralgias (noninflammatory joint pain, unlike arthritis, which is inflammatory). *Nausea. *Vomiting. *Sore throat ... In Europe, B. divergens is the primary cause of infectious babesiosis and is transmitted by I. ricinus.[4] ... This was the first demonstration that an arthropod could act as a disease vector to transmit an infectious agent to a ...

https://en.wikipedia.org/wiki/Babesiosis

Oral LP is a non infectious, chronic inflammatory condition that involves the oral mucosa and may be accompanied by skin ... Hellgren L (December 1970). "The prevalence of rheumatoid arthritis in different geographical areas in Sweden". Acta ...

https://en.wikipedia.org/wiki/Lupus_erythematosus–lichen_planus_overlap_syndrome

Learn why people get infectious arthritis, tests needed and how it is treated. ... Infectious or septic arthritis is a bacterial infection of the joint. ... ClinicalTrials.gov: Arthritis, Infectious (National Institutes of Health) * ClinicalTrials.gov: Arthritis, Reactive (National ... One type of infectious arthritis is reactive arthritis. The reaction is to an infection somewhere else in your body. The joint ...

https://medlineplus.gov/infectiousarthritis.html

Infectious arthritis in dogs is also referred to as bacterial or septic arthritis. As the name suggests, a bacterial infection ... Symptoms of infectious arthritis usually center around pain. This type of acute arthritis normally affects one specific area, ... Infectious arthritis in dogs is most commonly caused by a bacterial infection. Bacterial infections can arise from tick-borne ... Infectious arthritis is a dangerous condition that doesnt always end with a favorable outcome. Prognosis is better the earlier ...

https://www.vetinfo.com/infectious-arthritis-symptoms-in-dogs.html

Infectious arthritis is a condition in which the fluid and tissues of a joint become infected. The signs of infectious ... Infectious arthritis, also called septic arthritis, is an infection in the fluid and tissues of a joint. It is most commonly a ... If a case of infectious arthritis is bacterial, antibiotics should begin clearing it up within 48 hours. Fungal infectious ... you should consult a doctor immediately as you may have infectious arthritis. Those with chronic arthritis should consult a ...

http://www.wisegeek.com/what-is-infectious-arthritis.htm

Septic Arthritis (Infectious Arthritis) in Children. What is septic arthritis in children?. Septic arthritis is an infection in ... How is septic arthritis diagnosed in a child?. Early diagnosis of septic arthritis is important. This is to prevent long-term ( ... What are the symptoms of septic arthritis in a child?. The most common joints affected by septic arthritis are the knee, hip, ... Key points about septic arthritis in a child. *Septic arthritis is an infection in the joint fluid (synovial fluid) and joint ...

https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=90&ContentID=P01730&redir=urmc.rochester.edu

Nongonococcal infectious arthritis is an acute or subacute illness with potentially significant morbidity and mortality. It can ... encoded search term (Nongonococcal Infectious Arthritis) and Nongonococcal Infectious Arthritis What to Read Next on Medscape. ... to be mindful of the possibility that infectious arthritis and crystal-induced arthritis may be coexisting in a single joint, ... Nongonococcal Infectious Arthritis Workup. Updated: Dec 31, 2019 * Author: Edward Dwyer, MD; Chief Editor: Herbert S Diamond, ...

https://emedicine.medscape.com/article/334286-workup

Infectious Arthritis. What is infectious arthritis?. Click Image to Enlarge. Infectious arthritis is an infection in the joint ... Treatment for infectious arthritis. Specific treatment for infectious arthritis will be determined by your doctor based on:. * ... How is infectious arthritis diagnosed?. Prompt diagnosis of infectious arthritis is necessary to prevent permanent damage to ... What are the symptoms of infectious arthritis?. The most common joints affected by infectious arthritis are the knee, hip, ...

http://www.nyhq.org/diw/content.asp?pageid=P03180

Articles tagged with "infectious arthritis". ACR 2013 State-of-the-Art Clinical Symposium: Diagnosis and Management of ...

https://www.the-rheumatologist.org/tag/infectious-arthritis/

... (septic arthritis) is caused by a bacterial, viral, or fungal infection inside a ... Infectious arthritis usually affects one joint, but it can affect many joints. Symptoms may include:. *Severe pain with the ...

https://www.lancastergeneralhealth.org/Healthwise/Document.aspx?id=sti150808

An overview of arthritis Arthritis literally means "inflammation of a joint." It is a major cause of lost work time and serious ... Septic arthritis takes place when the organism causing the septic passes from the blood stream to the joint in the body. Septic ... Signs that Indicate you Suffer from Arthritis Many people start to feel pain and stiffness in their bodies over time. ... These Symptoms of Rheumatoid Arthritis will Tell you if you Have it or Not ...

http://www.onlymyhealth.com/septic-arthritis-symptoms-1298015446

Get information and read articles on Infectious Arthritis signs, symptoms, causes, treatment, prevention and diagnosis at ... Infectious Arthritis - Get information and read articles on Infectious Arthritis signs, symptoms, causes, treatment, prevention ...

http://www.onlymyhealth.com/infectious-arthritis-1295953606.html

Artificial Joint Infectious Arthritis (Prosthetic Joint Infection; Artificial Joint Infection; Prosthetic Joint Infectious ... By Steven Schmitt, MD, Associate Professor of Medicine;Head, Section of Bone and Joint Infections, Department of Infectious ...

http://www.merckmanuals.com/en-pr/home/bone,-joint,-and-muscle-disorders/bone-and-joint-infections/artificial-joint-infectious-arthritis

9 infectious arthritis, 28 gouty arthritis and 2 who had both of them simultaneously. Age, sex, time from onset of symptoms and ... It is difficult to rule out infectious arthritis from a gouty arthritis when the latter has been demonstrated by the existence ... infectious arthritis, gouty arthritis and both simultaneous, respectively ). The difference between PCT measure in the first ... Objectives To determine the usefulness of measurement of procalcitonin (PCT) to discrimine infectious and gouty arthritis in an ...

http://ard.bmj.com/content/72/Suppl_3/A309.2

The knee is the joint most frequently affected by infectious arthritis. Infectious arthritis is diagnosed by taking a sample of ... "Infectious arthritis" (open studies are recruiting volunteers) and 153 "Infectious arthritis" studies with "all" status. Visit ... Infectious arthritis is a painful swelling in the joints caused by a bacterial, viral, or fungal infection. Infectious ... TNFalpha blockers and infectious risk in rheumatoid arthritis]. Author(s): B Raffeiner, C Botsios, F Ometto, L Bernardi, A ...

http://www.diseaseinfosearch.org/result/3820

Acute Monarticular Arthritis. Chronic Monarticular Arthritis. Polyarticular Arthritis. Staphylococcus aureus. Mycobacterium ... Infectious Arthritis." Harrisons Principles of Internal Medicine, 18e Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, ... Infectious Arthritis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J. Longo D.L., Fauci A.S., Kasper D.L ... Approach to the Patient: Infectious Arthritis. ++. Aspiration of synovial fluid an essential element in the evaluation of ...

http://accesspharmacy.mhmedical.com/content.aspx?bookid=331§ionid=40727137

There is no single test that can confirm a diagnosis of infectious arthritis. As explained in this eMedTV resource, however, ... Doctors can use x-rays to help when diagnosing infectious arthritis. Depending on the type of infectious arthritis, early ... Tests Used to Diagnose Infectious Arthritis. Certain tests your healthcare provider may recommend to help diagnose infectious ... Before making an infectious arthritis diagnosis, the healthcare provider will also consider other conditions that share a ...

http://arthritis.emedtv.com/infectious-arthritis/diagnosing-infectious-arthritis-p2.html

Most cases of bacterial arthritis arise due to hematogenous spread. Risk factors for infectious arthritis include surgery or ... Arthritis due to Mycoplasma hominis can cause arthritis. Human parvovirus B19 is the most common cause of viral arthritis in ... Infectious arthritis may be due to many different microorganisms, including bacteria, fungi, mycobacteria, and viruses. Septic ... Tenosynovitis is rarely seen in other forms of infectious arthritis.. Symptoms of prosthetic joint infections include joint ...

http://www.cancertherapyadvisor.com/labmed/infectious-arthritis/article/611090/

Also referred to as septic arthritis, Bacterial arthritis, or Non-gonococcal bacterial arthritis, Infectious Arthritis is an ... Infectious arthritis can happen to people of any age, sex or gender. Infants can also be affected by infectious arthritis when ... Most of the time infectious arthritis will affect only one joint.. Infectious arthritis in younger, sexually active individuals ... 3 Gonococcal infectious arthritis present symptoms in one of two possible ways:. • Asymmetric polyarthritis, often associated ...

https://www.reliawire.com/infectious-arthritis-definition-symptoms/

So there is infectious arthritis. What diseases may cause this pathology? What specific symptoms does infectious arthritis? ... Infectious arthritis: etiology, pathogenesis and clinical course. Arthritis is a term that encompasses various inflammatory ... Infectious arthritis of the knee joint. Among all diseases of musculoskeletal system arthritis of the knee joint is the most ... It can be bacterial, and fungal infectious agents. Often infectious (or pyogenic) arthritis is a secondary disease, that is in ...

http://medicalj-center.info/diseases/traumatology/infectious-arthritis-etiology-pathogenesis-and-clinical-course.html

... of all cases of infectious arthritis, which can be caused by mosquito bites, infections, and injuries. ... The risk of death due to infectious arthritis increases if you have heart or kidney problems, rheumatoid arthritis, or a ... Led by Arthritis Consumer Experts and the Arthritis Research Centre of Canada, the Arthritis Broadcast Network (ABN) is a multi ... 2013 Arthritis Broadcast Network / Arthritis Consumer Experts / Arthritis Research Centre of Canada ...

http://arthritisbroadcastnetwork.org/2017/09/viruses-transmitted-mosquitos-associated-infectious-arthritis/

Infectious arthritis is new public health threat. - If you have high fever along with severe joint pain, it may be infectious ... Infectious arthritis is new public health threat IN , भारतीय समय - सोमवार, नवंबर 07, 2016 ...

http://pairsonnalites-au.blogspot.com/2016/11/infectious-arthritis-is-new-public.html

Doctors call this condition septic arthritis, bacterial arthritis, or infectious arthritis. ... Doctors call this condition septic arthritis, bacterial arthritis, or infectious arthritis.. Germs dont have to invade a joint ... Infectious arthritis. Mayo Clinic online... National Institute of Arthritis and Musculoskeletal Diseases. Questions and Answers ... Both septic arthritis and reactive arthritis can cause pain and swelling in a joint. Septic arthritis most often occurs in one ...

https://consumer.healthday.com/encyclopedia/arthritis-3/arthritis-management-news-40/infectious-arthritis-645415.html

... ANSWER Many organisms may infect the knee. Gonorrhea, a ...

https://www.webmd.com/pain-management/knee-pain/qa/how-is-an-infection-or-infectious-arthritis-described-and-treated

Make research projects and school reports about Infectious arthritis easy with credible articles from our FREE, online ... and pictures about Infectious arthritis at Encyclopedia.com. ... Septic arthritis What Is Infectious Arthritis?. Most of the ... Infectious Arthritis. Definition. Infectious arthritis, which is sometimes called septic arthritis or pyogenic arthritis, is a ... Arthritis, Infectious Complete Human Diseases and Conditions COPYRIGHT 2008 Gale Group. Arthritis, Infectious. What Is ...

https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/infectious-arthritis

swollen joints and pain from infectious arthritis are treated with antibiotics to stop the infection. sometimes, you may ... "Psoriatic Arthritis;" and "Systemic Lupus Erythematotus." The Merck Manual of Medical Information: "Infectious Arthritis." ... "Psoriatic Arthritis;" and "Systemic Lupus Erythematotus." The Merck Manual of Medical Information: "Infectious Arthritis." ... Swollen joints and pain from infectious arthritis are treated with antibiotics to stop the infection. Sometimes, you may ...

https://www.webmd.com/arthritis/qa/how-are-swollen-joints-joint-effusion-caused-by-infectious-arthritis-treated

... infectious arthritis) infection reaches joints through bloodstream. Injury or surgery infect joints & develop septic arthritis. ... The descriptions of septic arthritis (infectious arthritis) include diagnosis of Septic arthritis (infectious arthritis) and it ... age is the key factors for diagnosis of Septic arthritis (infectious arthritis). Septic arthritis (infectious arthritis) is one ... Causes of Septic (Infectious) Arthritis. The causes of septic arthritis (infectious arthritis) can include infection by ...

http://www.home-remedies-for-you.com/blog/septic-arthritis-infectious-arthritis.html

Infectious arthritis is a type of inflammatory arthritis that affects young and old people alike. It is usually caused by ... Infectious arthritis is a type of inflammatory arthritis that affects young and old people alike. It is usually caused by ... If undetected or untreated, infectious arthritis can destroy a joint within days. So, if an infection is suspected, diagnostic ...

https://bodyandhealth.canada.com/channel/infection/overview/infectious-arthritis

... also known as septic arthritis or pyogenicarthritis, is a joint inflammation caused by infection by one of a number of ... What Is Infectious Arthritis?. Infectious arthritis, which is also called septic arthritis or pyogenicarthritis, is a joint ... Infectious Arthritis Treatment. *Antibiotics are prescribed to treat bacterial infections and Lyme arthritis. These drugs ... Fungal infection may cause infectious arthritis; it typically progresses more slowly and is milder than bacterial arthritis. ...

http://www.healthcommunities.com/arthritis/infectious-arthritis-facts.shtml

What is infectious arthritis? Meaning of infectious arthritis medical term. What does infectious arthritis mean? ... Looking for online definition of infectious arthritis in the Medical Dictionary? infectious arthritis explanation free. ... Related to infectious arthritis: Lyme disease, Reactive arthritis, Metabolic arthritis. Infectious Arthritis. Definition. ... infectious arthritis. Septic arthritis, see there. arthritis. inflammation of a joint. See also arthropathy, polyarthritis. ...

https://medical-dictionary.thefreedictionary.com/infectious+arthritis

It is also called septic arthritis. Infectious arthritis is usually not a long-term or chronic illness. Treated promptly and ... However, without proper treatment, infectious arthritis can result in serious damage to the joints involved and may ... Infectious arthritis is a form of arthritis that is produced by an infection. ... properly, it is generally a curable form of arthritis. ... Basics of Infectious Arthritis. Infectious arthritis is a form ...

http://www.orthop.washington.edu/?q=patient-care/articles/arthritis/infectious-arthritis.html

General Illness Information. Common Name: ARTHRITIS, INFECTIOUS. Medical Term: Septic Arthritis. Description:. Painful swelling in an inflamed joint resulting from infection in the synovial fluid and the tissues of the joint. Any joint may be involved, but larger joints are more commonly affected.. Causes:. Infection is mainly caused by bacteria which usually enter the joint through the blood stream. However, a joint can be infected directly if it is contaminated by injury, injection or surgery.. ...

https://www.rxmed.com/b.main/b1.illness/b1.1.illnesses/arthritis,_infectious.html

Infectious Arthritis. Infectious arthritis (septic arthritis) is caused by a bacterial, viral, or fungal infection inside a ... Infectious arthritis usually affects one joint, but it can affect many joints. Symptoms may include:. *Severe pain with the ...

https://www.parkviewmc.com/community-education/health-library/document-viewer/?id=sti150808

Post-Chikungunya Rheumatoid Arthritis, Saint Martin. Emerging Infectious Diseases. 2015;21(3):530-532. doi:10.3201/ ... rheumatoid arthritis, and psoriatic arthritis (2,4,5). Although the proportion of patients with chronic disease has decreased, ... Post-chikungunya chronic arthritis-our experience with DMARDs over two year follow up. J Assoc Physicians India. 2011;59:83-6 . ... A report of 21 cases of rheumatoid arthritis following chikungunya fever. A mean follow-up of two years. Joint Bone Spine. 2009 ...

https://wwwnc.cdc.gov/eid/article/21/3/14-1397_article

... in reactive arthritis, 20% in enteric arthritis or psoriatic arthritis). All of these diseases can be viewed as seronegative ... Classification of Reactive Arthritides. Emerging Infectious Diseases. 1998;4(3):510-512. doi:10.3201/eid0403.980350.. ... Blumberg, D. R., & Sloan, V. S. (1998). Classification of Reactive Arthritides. Emerging Infectious Diseases, 4(3), 510-512. ... Reactive arthritis is so named because it is felt that the arthritis and other inflammatory manifestations are an immune ...

https://wwwnc.cdc.gov/eid/article/4/3/98-0350_article

Acute nongonococcal infectious arthritis. Evaluation of risk factors, therapy, and outcome Arthritis Rheum. 1980 Aug;23(8):889- ... Arthritis, Infectious / diagnosis* * Arthritis, Infectious / drug therapy * Arthritis, Infectious / surgery * Arthritis, ...

https://pubmed.ncbi.nlm.nih.gov/6773530/?dopt=Abstract

Chronic infectious arthritis. Chronic infectious arthritis is usually caused by Mycobacterium tuberculosis (the main cause of ... Acute infectious arthritis. Acute infectious arthritis that is caused by bacteria begins quickly. It accounts for 95% of ... Chronic infectious arthritis. Chronic infectious arthritis begins gradually over several weeks. It accounts for 5% of ... Acute infectious arthritis. Acute infectious arthritis is usually caused by bacteria and viruses. ...

http://www.merckmanuals.com/en-ca/home/bone,-joint,-and-muscle-disorders/bone-and-joint-infections/infectious-arthritis

Distinguish infectious from gouty arthritis or pseudogout by analysis of joint fluid. ... Gram stains are negative in about 50% of cases of bacterial arthritis (and 75% of cases of gonococcal arthritis), but cultures ... Margaretten, ME, Kohlwes, J, Moore, D, Bent, S. "Does this adult patient have septic arthritis?". JAMA. vol. 297. 2007. pp. ... Margaretten, ME, Kohlwes, J, Moore, D, Bent, S. "Does this adult patient have septic arthritis?". JAMA. vol. 297. 2007. pp. ...

https://www.clinicaladvisor.com/home/decision-support-in-medicine/critical-care-medicine/infections-of-joints-septic-arthritis-infectious-arthritis/

Orthopedics , OCOSH Classification , Joint Diseases , Arthritis , Septic Arthritis , Septic Arthritis eMedicine Infectious ... inflammatory arthritis, bacterial septic arthritides, bacterial septic arthritis, suppurative arthritis, Neisseria gonorrhoeae ... crystalline arthritis, Lyme disease, Lyme arthritis, prosthetic joint infections, PJI, rheumatoid arthritis. John L Brusch, MD ... Septic Arthritis eMedicine Infectious Diseases. Visit Resource Review It Rate It Bookmark It ...

http://www.orthopaedicweblinks.com/Detailed/13954.html

Science 89:228-229, 1939 2. Cole BC, Ward JR, Smith CB: Studies on the infectious etiology of rheumatoid arthritis. Arthritis ... Studies on the infectious etiology of human rheumatoid arthritis.. код для вставки. код для вставки на сайт или в блог. Ширина ... An infectious etiology for human rheumatoid arthritis remains a n attractive hypothesis despite numerous conflicting and ... Chandler RW, Robinson H, Masi AT: Serological investigations for evidence of an infectious etiology of rheumatoid arthritis. ...

https://www.docme.ru/doc/2170563/studies-on-the-infectious-etiology-of-human-rheumatoid-ar..

... is used to designate that form of chronic multiple arthritis more commonly called chronic infectious or atrophic arthritis. ... Review: In rheumatoid arthritis, TNF-α inhibitors do not differ from placebo or DMARDs for all-cause mortality Annals of ... In patients with rheumatoid arthritis, bDMARD therapy was not associated with malignant neoplasms Annals of Internal Medicine; ... In high-risk patients with arthritis and previous upper GI bleeding, celecoxib vs naproxen reduced recurrent bleeding Annals of ...

https://annals.org/aim/article-abstract/670050/bacteriological-investigations-blood-synovial-fluid-subcutaneous-nodules-rheumatoid-chronic-infectious

Other factors that may need to be examined are possibilities for the onset of future joint problems, rheumatoid arthritis or problems with the immune system caused by the infection. (vetinfo.com)
Several conditions can cause jaw pain (TMJ pain) such as osteoarthritis, rheumatoid arthritis, infectious arthritis and several other medical conditions. (nethealthbook.com)

Symptoms of infectious arthritis are similar to other forms, such as osteoarthritis or hip dysplasia, making this particular condition difficult to diagnose. (vetinfo.com)
Symptoms of infectious arthritis usually center around pain. (vetinfo.com)
What are the symptoms of septic arthritis in a child? (rochester.edu)
People who suffer from a more chronic infectious arthritis that's caused by mycobacteria will have less dramatic symptoms. (reliawire.com)

This type of acute arthritis normally affects one specific area, so the dog may seem to be lame in only one leg. (vetinfo.com)
Leukocytosis is common in patients with acute bacterial arthritis. (medscape.com)
90%) in persons with acute bacterial arthritis. (medscape.com)
Acute septic arthritis. (medscape.com)

Vaccinations have been known to cause this type of arthritis, as has severe gum disease, which tends to be common among canines. (vetinfo.com)
But children who have an open skin wound and an impaired immune systems due to diabetes, kidney disease, HIV infection, or cancer may be at greater risk of septic arthritis. (rochester.edu)
Other bacteria causing infectious arthritis include the spirochete bacterium which causes Lyme disease , E. coli , Pseudomonas spp. (reliawire.com)
Severe forms of the disease result in chronic incapacitating arthralgia and arthritis. (edu.au)
RRV as an infection model has the potential to provide key insights into such disease processes, particularly as many viruses, other than alphaviruses, are known to cause infectious arthritides. (edu.au)

Infectious arthritis is an infection in the joint. (medlineplus.gov)
Sometimes, reactive arthritis is set off by an infection in the bladder, or in the urethra, which carries urine out of the body. (medlineplus.gov)
This is considered the most dangerous form of arthritis, however, due to the potential for the bacterial infection to spread to other parts of the body. (vetinfo.com)
Infectious arthritis in dogs is most commonly caused by a bacterial infection. (vetinfo.com)
Infectious arthritis (septic arthritis) is caused by a bacterial, viral, or fungal infection inside a joint. (lancastergeneralhealth.org)
Also referred to as septic arthritis, Bacterial arthritis, or Non-gonococcal bacterial arthritis, Infectious Arthritis is an infection in the fluid in tissues of the joints that is usually caused by bacteria, but sometimes is triggered by viruses or fungi. (reliawire.com)
Infants can also be affected by infectious arthritis when an infection settles in one of their joints. (reliawire.com)
An arthritis that involves infection by a pathogen located_in joint. (jensenlab.org)

One type of infectious arthritis is reactive arthritis. (medlineplus.gov)
Another form of reactive arthritis starts with eating food or handling something that has bacteria on it. (medlineplus.gov)
What Is Reactive Arthritis? (medlineplus.gov)

The most common type of bacteria that causes septic arthritis is called Staphylococcus aureus. (rochester.edu)
Infectious arthritis in younger, sexually active individuals could be caused by Neisseria gonorrhea bacteria. (reliawire.com)
The most frequent cause of infectious arthritis is bacteria. (reliawire.com)

Most kinds of arthritis cause pain and swelling in your joints. (medlineplus.gov)
This imaging test uses a tiny amount of a radioactive substance to look for arthritis changes in the joints. (rochester.edu)
Infectious arthritis usually affects one joint, but it can affect many joints. (lancastergeneralhealth.org)

Blood culture results are positive in approximately 33%-50% of patients with nongonococcal bacterial arthritis. (medscape.com)

Six patients (mean age 39.5 years) with chronic SCJ infectious arthritis were included in the study. (biomedcentral.com)
This procedure was utilized in six patients with infectious arthritis. (biomedcentral.com)

Bleeding from the knee results in an infectious arthritis because the blood enters the joint space. (reliawire.com)

Smith JW, Chalupa P, Shabaz Hasan M. Infectious arthritis: clinical features, laboratory findings and treatment. (medscape.com)

A microscopic examination of synovial fluid for monosodium urate crystals and calcium pyrophosphate crystals is performed to exclude crystal-induced arthritis (eg, gout or pseudogout). (medscape.com)

If indicated, arthrocentesis for synovial fluid analysis is the single most important diagnostic procedure for evaluating infectious arthritis. (medscape.com)

García-De La Torre I, Nava-Zavala A. Gonococcal and nongonococcal arthritis. (medscape.com)

What are the possible complications of septic arthritis in a child? (rochester.edu)

Septic arthritis often needs treatment right away with antibiotics. (rochester.edu)

To diagnose infectious arthritis, your health care provider may do tests of your blood, urine, and joint fluid. (medlineplus.gov)

What is septic arthritis in children? (rochester.edu)

Radionuclide studies (eg, bone scans) yield positive results for any inflammatory arthritis and thus have poor specificity. (medscape.com)

Case Studies and Literature Review of Pneumococcal Septic Arthritis in Adults. (medscape.com)

It is important, however, to be mindful of the possibility that infectious arthritis and crystal-induced arthritis may be coexisting in a single joint, though such coexistence is reportedly very uncommon. (medscape.com)

If your physician suspects that you may have an infectious arthritic joint they will require a sample of the fluid which is removed with a sterile needle as soon as possible. (reliawire.com)

Chen Y, Huang Z, Fang X, Li W, Yang B, Zhang W. Diagnosis and treatment of mycoplasmal septic arthritis: a systematic review. (medscape.com)
Flowchart of the three stages of the surgical treatment for sternoclavicular joint septic arthritis. (biomedcentral.com)

Doctors call this condition septic arthritis, bacterial arthritis, or infectious arthritis. (healthday.com)
Both septic arthritis and reactive arthritis can cause pain and swelling in a joint. (healthday.com)
Septic arthritis most often occurs in one joint, usually a knee, shoulder, or wrist, but it can involve several. (healthday.com)
Septic arthritis is more common in the very young, the very old, and anyone with a weakened immune system, including IV drug users and patients with cancer, diabetes, or HIV. (healthday.com)
Septic arthritis is generally the easiest to spot. (healthday.com)
Medications attack septic arthritis at the source. (healthday.com)
With prompt treatment, most people with septic arthritis recover completely. (healthday.com)
Infectious arthritis in dogs is also referred to as bacterial or septic arthritis. (vetinfo.com)
Infectious arthritis, also called septic arthritis, is an infection in the fluid and tissues of a joint. (wisegeek.com)
Infectious arthritis, which is sometimes called septic arthritis or pyogenic arthritis, is a serious infection of the joints characterized by pain, fever, occasional chills, inflammation and swelling in one or more joints, and loss of function in the affected joints. (encyclopedia.com)
Septic arthritis is considered a medical emergency because of the damage it causes to bone as well as cartilage, and its potential for creating septic shock, which is a potentially fatal condition. (encyclopedia.com)
Viruses and bacteria are most common source of Septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Additionally, age is the key factors for diagnosis of Septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Septic arthritis (infectious arthritis) is one of the major bone related disease of the world, nearly 2 percent population in United States is affected by Septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Therefore, it becomes essential to know more about Septic arthritis (infectious arthritis). (home-remedies-for-you.com)
There are some reasons are useful to know if a person is affected from Septic arthritis (infectious arthritis), the Causes of septic arthritis (infectious arthritis) include infection by bacteria and it may be caused by viruses and fungi. (home-remedies-for-you.com)
Therefore, it becomes essential to know more about causes of septic arthritis (infectious arthritis) to prevent its serious side effects. (home-remedies-for-you.com)
Sometimes, due to infection people may develop of septic arthritis (infectious arthritis) and it occurs when bacteria reaches a joint. (home-remedies-for-you.com)
The Causes of septic arthritis (infectious arthritis) commonly found in young children and young babies. (home-remedies-for-you.com)
However, hemophilus influenzae and gram-negative bacteria are common causes of septic arthritis (infectious arthritis). (home-remedies-for-you.com)
The gonococci, staphylococci, streptococci, and mycobacterium are the causes of septic arthritis (infectious arthritis). (home-remedies-for-you.com)
Due to weak immune system, people may develop symptoms of septic arthritis. (home-remedies-for-you.com)
The descriptions of septic arthritis (infectious arthritis) include diagnosis of Septic arthritis (infectious arthritis) and it may include complete physical examination and complete medical history of the patients. (home-remedies-for-you.com)
The diagnosis of Septic arthritis (infectious arthritis) may include removal of joint fluid to examine for white blood cells and bacteria and blood tests to detect bacteria. (home-remedies-for-you.com)
The treatment of Septic arthritis (infectious arthritis) may depends on overall health and medical history of patients and extend of the condition. (home-remedies-for-you.com)
People those are suffering from Septic arthritis (infectious arthritis) symptoms usually go for doctors to take advice to prevent severe side effects of Septic arthritis (infectious arthritis). (home-remedies-for-you.com)
The causes of septic arthritis (infectious arthritis) can include infection by bacteria and it may b. (home-remedies-for-you.com)
Septic arthritis is a type of infection that affects the joint. (home-remedies-for-you.com)
What is septic arthritis in children? (rochester.edu)
What causes septic arthritis in a child? (rochester.edu)
The most common type of bacteria that causes septic arthritis is called Staphylococcus aureus. (rochester.edu)
Which children are at risk for septic arthritis? (rochester.edu)
Septic arthritis may occur without any known risk factors. (rochester.edu)
But children who have an open skin wound and an impaired immune systems due to diabetes, kidney disease, HIV infection, or cancer may be at greater risk of septic arthritis. (rochester.edu)
What are the symptoms of septic arthritis in a child? (rochester.edu)
How is septic arthritis diagnosed in a child? (rochester.edu)
Early diagnosis of septic arthritis is important. (rochester.edu)
How is septic arthritis treated in a child? (rochester.edu)
Septic arthritis often needs treatment right away with antibiotics. (rochester.edu)
What are the possible complications of septic arthritis in a child? (rochester.edu)
Septic arthritis can cause joint damage. (rochester.edu)
Infectious arthritis, which is also called septic arthritis or pyogenicarthritis, is a joint inflammation due to infection by one of a number of microorganisms. (healthcommunities.com)
Infectious arthritis (septic arthritis) is caused by a bacterial, viral, or fungal infection inside a joint. (parkviewmc.com)
Septic arthritis in immunocompetent and immunosuppressed hosts. (medscape.com)
Case Studies and Literature Review of Pneumococcal Septic Arthritis in Adults. (medscape.com)
Kingella kingae as the Main Cause of Septic Arthritis: Importance of Molecular Diagnosis. (medscape.com)
Chen Y, Huang Z, Fang X, Li W, Yang B, Zhang W. Diagnosis and treatment of mycoplasmal septic arthritis: a systematic review. (medscape.com)
Septic arthritis takes place when the organism causing the septic passes from the blood stream to the joint in the body. (onlymyhealth.com)
A general tendency to feel tired, fatigued and weak after short spans of time can also be seen in the patients of septic arthritis. (onlymyhealth.com)
Failure to recognize and to appropriately treat septic arthritis results in significant rates of morbidity and may even lead to death. (orthopaedicweblinks.com)
Because of the increasing use of prosthetic joints, infection associated with these devices may be the most common and challenging type of septic arthritis encountered by most clinicians. (orthopaedicweblinks.com)
The most common type of bacteria that cause septic arthritis is called Staphylococcus aureus, or staph. (brighamandwomens.org)
Serum procalcitonin for discrimination between septic and non-septic arthritis. (bmj.com)
Septic arthritis and osteomyelitis often present with a subacute course of illness and vague signs and symptoms. (ebmedicine.net)
This issue provides evidence-based recommendations for the diagnosis and management of pediatric patients with septic arthritis and/or osteomyelitis and offers guidance for appropriate antibiotic treatment. (ebmedicine.net)
Septic arthritis and osteomyelitis in pediatric patients represent true emergencies, and can quickly threaten life and limb. (ebmedicine.net)
Septic arthritis and osteomyelitis can occur concurrently, so suspicion for one should also prompt investigation for the other. (ebmedicine.net)
This issue reviews the current literature and provides an evidence-based approach for the evaluation and management of pediatric patients with septic arthritis and osteomyelitis. (ebmedicine.net)
Septic arthritis of the ankle as seen in a 3 month old. (chromoscience.com)
Also called septic arthritis , infectious arthritis can be either an acute or a chronic condition. (chromoscience.com)
S. aureus is the most common cause of acute septic arthritis in the general population of adults and young children. (chromoscience.com)
Septic arthritis is uncommon from age 3 to adolescence, at which time the incidence increases again (appearing as gonococcal arthritis in females with cervical gonorrhea). (health-cares.net)
Children with septic arthritis are more likely than adults to be infected with group B streptococcus and Haemophilus influenza. (health-cares.net)
Acute septic arthritis tends to be caused by organisms such as staphylococcus, streptococcus (pneumoniae) and group B streptococcus while chronic septic arthritis (which occurs less frequently) is caused by organisms such as Mycobacterium tuberculosis and Candida albicans. (health-cares.net)
Patients with recent joint injuries or surgery, or patients receiving medications injected directly into a joint are also at a greater risk for developing septic arthritis. (health-cares.net)
Typically, women and male homosexuals are at greater risk for septic arthritis than are male heterosexuals. (health-cares.net)
Septic arthritis develops when bacteria spread from a source of infection through the bloodstream to a joint or the joint is directly infected by traumatic penetration. (health-cares.net)
What're the symptoms of septic arthritis? (health-cares.net)
The symptoms of septic arthritis (infectious arthritis) include swelling in the infected joint and pain when the joint is moved. (health-cares.net)
What is the treatment for septic arthritis? (health-cares.net)
The goal of treatment for septic arthritis is to eliminate the infection with antibiotic therapy. (health-cares.net)
Septic arthritis requires immediate treatment. (health-cares.net)
Septic arthritis generally refers to a bacterial process, but the entity also includes infection due to fungi and mycobacteria. (cancertherapyadvisor.com)
Septic arthritis is considered a rheumatologic emergency because of the potential for rapid joint destruction and patient decompensation. (cancertherapyadvisor.com)
In adults with nongonococcal septic arthritis, Staphylococcus aureus (including methicillin resistant S. aureus) and Streptococcus spp. (cancertherapyadvisor.com)
Gram-negative bacilli are recovered from 5-20% of patients with septic arthritis. (cancertherapyadvisor.com)
3 people with Infectious arthritis / Septic arthritis have taken the SF36 survey. (diseasemaps.org)
Also referred to as septic arthritis, Bacterial arthritis, or Non-gonococcal bacterial arthritis, Infectious Arthritis is an infection in the fluid in tissues of the joints that is usually caused by bacteria, but sometimes is triggered by viruses or fungi. (reliawire.com)
How does one cure septic arthritis? (answers.com)
In order to cure septic arthritis, antibiotics will be needed to make sure the infection is contained and that it will not spread. (answers.com)
Infectious arthritis, which is sometimes called septic arthritis or pyogenic arthritis, is a serious infection of the joints. (answers.com)
Septic arthritis is infection of one or more joints by microorganisms. (medicinenet.com)
Septic arthritis can be caused by fungal, viral, and bacterial infections . (medicinenet.com)
Risks for the development of septic arthritis include a patient taking immune-suppression medicines, intravenous drug abuse , past joint disease, injury or surgery, and underlying medical illnesses, including diabetes , alcoholism , sickle cell disease , rheumatic diseases, and immune deficiency disorders. (medicinenet.com)
Septic arthritis treatment requires a patient to take antibiotics and a health care professional to drain the infected joint fluid from the joint. (medicinenet.com)
What microbes cause septic arthritis? (medicinenet.com)
Septic arthritis can be caused by bacteria, viruses , and fungi. (medicinenet.com)
The most common causes of septic arthritis are bacterial, including Staphylococcus aureus ( staph ) and Haemophilus influenzae . (medicinenet.com)
Other bacteria that can cause septic arthritis include Mycobacterium tuberculosis and the spirochete bacterium that causes Lyme disease . (medicinenet.com)
Fungi that can cause septic arthritis include Histoplasma , Coccidioides , and Blastomyces . (medicinenet.com)
Is septic arthritis contagious? (medicinenet.com)
Who is at risk of developing septic arthritis? (medicinenet.com)
Chronic septic arthritis is very rare and is caused by microorganisms like M. tuberculosis. (findarthritistreatment.com)
This entry was posted in Causes , Featured and tagged common causes of infectious arthritis , factors causing infectious arthritis , infectious arthritis , infectious arthritis causes , septic arthritis . (findarthritistreatment.com)
Joint inflammation may also be caused by infection, which can lead to septic arthritis. (hpathy.com)
Septic arthritis is a painful infection of joint. (kasturihospitals.com)
Staphylococcus, the most common bacteria, is the main cause of septic arthritis of joints. (kasturihospitals.com)
Joints of hip, shoulder, knee, wrist and elbow are most often affected with septic arthritis. (kasturihospitals.com)
The doctor will initially undergo certain tests to confirm the diagnosis of septic arthritis infection. (kasturihospitals.com)
At initial stages, the pain due to septic arthritis is very high. (kasturihospitals.com)
Traditional inflammatory markers are generally unhelpful in discerning septic arthritis from inflammatory joint disease due to their lack of specificity. (springer.com)
Thirty-six patients presenting with an acute flare of chronic rheumatic arthritis, 31 with crystal-induced arthritis and 23 with septic arthritis were included. (springer.com)
Subgroup analysis excluding patients with septic arthritis without concurrent bacteremia, and likewise exclusion of the patients with septic arthritis caused by coagulase negative staphylococci, both improved the diagnostic accuracy of CD64 and PCT, but not of WBC and CRP. (springer.com)
The diagnosis of septic arthritis depends largely on positive microbiological cultures, but the technique is time-consuming and often delays the final diagnosis by 2-3 days. (springer.com)
In general, septic arthritis is characterized by its presentation as either acute or chronic. (renalandurologynews.com)
Some authors suggest that in 50% of patients a careful history and physical examination will suggest a primary site or origin for the pathogen causing acute or chronic septic arthritis. (renalandurologynews.com)
Despite advances in antimicrobial and surgical therapy, septic arthritis remains a rheumatologic emergency that can lead to rapid joint destruction and irreversible loss of function. (springer.com)
To the best of our knowledge, Streptococcus gordonii has not yet been described as agent of septic arthritis. (springer.com)
We describe here two cases of septic arthritis due to Streptococcus gordonii . (springer.com)
It gives us an opportunity to review epidemiology, diagnosis criteria and management of septic arthritis. (springer.com)
Although implication of S. gordonii as aetiologic agent of subacute endocarditis is well known, this organism is a rare cause of septic arthritis. (springer.com)
Treatment for septic arthritis was undertaken, and arthroscopic lavage of the joint performed. (springer.com)
Septic Arthritis of Native Joints. (medscape.com)
McGuire NM, Kauffman CA. Septic arthritis in the elderly. (medscape.com)
Baraboutis I, Skoutelis A. Streptococcus pneumoniae septic arthritis in adults. (medscape.com)
Raad J, Peacock JE Jr. Septic arthritis in the adult caused by Streptococcus pneumoniae: a report of 4 cases and review of the literature. (medscape.com)
Margaretten ME, Kohlwes J, Moore D, Bent S. Does this adult patient have septic arthritis? (medscape.com)
Ross JJ, Shamsuddin H. Sternoclavicular septic arthritis: review of 180 cases. (medscape.com)
Daily needle aspiration versus surgical lavage for the treatment of bacterial septic arthritis in adults. (medscape.com)
What are the treatment options for septic arthritis if antibiotic therapy fails? (medscape.com)

According to the National Institute of Arthritis and Musculoskeletal Diseases about 80 percent of patients with reactive arthritis have a particular gene called HLA-B27. (healthday.com)
National Institute of Arthritis and Musculoskeletal Diseases. (healthday.com)
Bone scanning is a method to evaluate any degenerative and arthritis changes in the joints to detect tumors and bone diseases and this tests is done in the case of pain and inflammation. (home-remedies-for-you.com)
There are various forms of arthritis among which some are associated with other diseases or infectio. (home-remedies-for-you.com)
Spondylitis may occur in reactive arthritis, psoriatic arthritis, or the arthropathy associated with inflammatory bowel disease, but is less common in these diseases (approximately 50% in reactive arthritis, 20% in enteric arthritis or psoriatic arthritis). (cdc.gov)
Supported by the National Institutes of Arthritis and Metabolic Diseases grant No. AM02255 and by a grant from the Kroc Foundation. (docme.ru)
Nearly two thirds of people with arthritis are younger than age 65, and are affected by over 100 types of arthritis, rheumatic diseases, and related conditions. (acufinder.com)
For example, how many infectious diseases are capable of producing vesicular rash and arthritis in American children? (gideononline.com)
Juvenile arthritis is the term used to describe joint and rheumatic diseases that affect children and teens. (arthritis.org)
Arthritis is a term that encompasses various inflammatory diseases of the joints. (medicalj-center.info)
The inflammatory process, in particular, could be the result of various infectious diseases. (medicalj-center.info)
In a later age, children increasingly suffer from various infectious diseases. (medicalj-center.info)
People suffering from diseases such as HIV, Cancer etc. that can potentially weaken the immune system make them more prone to Infectious Arthritis. (findarthritistreatment.com)
Prion diseases - also known as transmissible spongiform encephalopathies (TSEs) - are infectious brain conditions that affect people and animals. (healthcanal.com)
The Bioinformatics Resource Centers (BRCs) for Infectious Diseases program was initiated in 2004 with the main objective of collecting, archiving, updating, and integrating a variety of research data and providing such information through user friendly interfaces and computational analysis tools to be made freely available to the scientific community. (nih.gov)
The Infectious Diseases Management Program (IDMP) at UCSF is an interprofessional and interhospital collaboration aimed at improving antimicrobial use and the care of patients with infections. (ucsf.edu)
Red Book: Report of the Committee on Infectious Diseases. (cdc.gov)
The first group are the non-infectious diseases to consider and the second group are the infection-related conditions. (roboskin.org)
As with many infectious diseases, management or environmental factors that stress the pig or depress the immune response can precipitate systemic disease or an infectious arthritis. (merckvetmanual.com)
and changing rations are all major stresses that can lead to development of infectious arthritides or neurologic diseases that affect movement. (merckvetmanual.com)
The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. (medscape.com)
Executive summary: diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. (medscape.com)

One type of infectious arthritis is reactive arthritis. (medlineplus.gov)
What Is Reactive Arthritis? (medlineplus.gov)
This is called reactive arthritis. (healthday.com)
Reactive arthritis can result from a bout of salmonella, shigella, and campylobacter contracted through food poisoning. (healthday.com)
A case of reactive arthritis can also follow certain sexually transmitted infections, including chlamydia, gonorrhea, and HIV. (healthday.com)
Reactive arthritis is most common among men in their 20s or 30s. (healthday.com)
Reactive arthritis is a little less clear-cut. (healthday.com)
Most patients with reactive arthritis are treated with nonsteroidal anti-inflammatory drugs, like indomethacin (Indocin) or ibuprofen (Motrin). (healthday.com)
Likewise, most people with reactive arthritis get better with treatment. (healthday.com)
Questions and Answers About Reactive Arthritis. (healthday.com)
Reactive arthritis: What you should know. (healthday.com)
Reactive arthritis (Reiter's syndrome). (healthday.com)
In reactive arthritis, the joint is inflamed but not actually infected. (merckmanuals.com)
Obtain urine test for chlamydia and stool cultures for bacterial pathogens if reactive arthritis is a possibility, even in the absence of genital or intestinal symptoms. (clinicaladvisor.com)
Reactive arthritis, a sterile inflammatory process, may be the consequence of an infectious process located elsewhere in the body. (orthopaedicweblinks.com)
Reactive arthritis happens most commonly after infections of the genital and gastrointestinal tracts. (cdc.gov)
Lauhio A, Lahdevirta J, Janes R, Kontiainen S, Repo H. Reactive arthritis associated with Shigella sonnei Arthritis. (cdc.gov)
Reactive arthritis associated with Shigella sonnei . (cdc.gov)
Hannu T. Reactive arthritis. (medscape.com)
The term "reactive arthritis" is strongly preferred and increasingly used as a substitute for this designation because Hans Conrad Julius Reiter was not the first to describe the syndrome, his conclusions regarding its pathogenesis were incorrect, and because he committed war crimes as a Nazi at Buchenwald concentration camp during World War II. (wikipedia.org)
Reactive arthritis is an RF-seronegative, HLA-B27-linked arthritis often precipitated by genitourinary or gastrointestinal infections. (wikipedia.org)
Patients with HIV have an increased risk of developing reactive arthritis as well. (wikipedia.org)
Because common systems involved include the eye, the urinary system, and the hands and feet, one clinical mnemonic in reactive arthritis is "Can't see, can't pee, can't climb a tree. (wikipedia.org)
The presence of keratoderma blennorrhagica is diagnostic of reactive arthritis in the absence of the classical triad. (wikipedia.org)
Ocular involvement (mild bilateral conjunctivitis) occurs in about 50% of men with urogenital reactive arthritis syndrome and about 75% of men with enteric reactive arthritis syndrome. (wikipedia.org)
Eye involvement typically occurs early in the course of reactive arthritis, and symptoms may come and go. (wikipedia.org)
Dactylitis, or "sausage digit", a diffuse swelling of a solitary finger or toe, is a distinctive feature of reactive arthritis and other peripheral spondylarthritides but can also be seen in polyarticular gout and sarcoidosis. (wikipedia.org)

It is important to keep in mind that infectious arthritis can coexist with other forms of arthritis, gout, rheumatic fever, Lyme disease, or other disorders that can cause a combination of joint pain and fever. (encyclopedia.com)
These treatments are also applied to inflammatory types of arthritis, such as RA, along with anti-inflammatory medications such as corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs), and a relatively new class of drugs known as biologics. (medicalnewstoday.com)
These markers are often elevated regardless of whether the inflammatory stimulus is trauma, rheumatic disorders or infectious disease [ 3 ]. (springer.com)

Although any infectious agent may cause arthritis, bacterial pathogens are the most significant because of their rapidly destructive nature. (orthopaedicweblinks.com)
This is mainly an infectious disease of the upper respiratory tract caused by pathogens such as streptococci and staphylococci. (medicalj-center.info)

Many forms of arthritis and related conditions can cause pain, stiffness and swelling in the hips. (arthritis.org)
It can occur in the toes with several different forms of arthritis causing problems. (medicalnewstoday.com)
It offers potential relief and rejuvenation for all forms of arthritis, safely, naturally and without side effects. (health-cares.net)
These are the most devastating forms of arthritis because if you miss the diagnosis, a person can die. (arthritisbroadcastnetwork.org)
Differential diagnosis can be a difficult undertaking because so many forms of arthritis, particularly inflammatory forms of arthritis look alike. (roboskin.org)

this was previously referred to as Reiter's syndrome, Reiter's disease or Reiter's arthritis. (wikipedia.org)

Other sporadic causes of osteomyelitis and/or arthritis in poultry include coagulase-negative Staphylococcus spp, Pasteurella multocida , Ornithobacterium rhinotracheale , Trueperella (Arcanobacterium) pyogenes , Enterococcus spp, Streptococcus spp, Salmonella spp, Streptobacillus moniliformis , and Aspergillus spp. (merckvetmanual.com)

Vaccinations have been known to cause this type of arthritis, as has severe gum disease, which tends to be common among canines. (vetinfo.com)
Can Acupuncture treat this type of Arthritis? (acufinder.com)
Information about symptoms, health and lifestyle habits will help determine the type of arthritis you have. (arthritis.org)
Medications will depend on the type of arthritis. (medicalnewstoday.com)
More than 50 million adults and 300,000 children have some type of arthritis. (arthritis.org)
Arthritis diagnosis often begins with a primary care physician, who performs a physical exam and may do blood tests and imaging scans to help determine the type of arthritis. (arthritis.org)
It really depends on what type of arthritis you have. (answers.com)
Yes, Arthritis Curable but depends on which type of arthritis. (answers.com)
A type of arthritis that develop at a young age is ruemetoid (sp? (answers.com)
By identifying infected joint fluid, doctors may make a diagnosis of this type of arthritis . (medicinenet.com)
What Type of Arthritis Do You Have? (healthline.com)
The causes and treatment options available vary from one type of arthritis to another. (healthline.com)
To find the best treatment and management strategies, it's important to determine the type of arthritis you have. (healthline.com)
this type of arthritis is not well known to most people across the globe. (findarthritistreatment.com)
Type of arthritis in which cartilage loses its elasticity, and becomes stiff. (hpathy.com)

Treated promptly and properly, it is generally a curable form of arthritis. (washington.edu)
According to the Centers for Disease Control and Prevention (CDC), 54.4 million adults in the United States have received a diagnosis of some form of arthritis. (medicalnewstoday.com)
With this form of arthritis, microbes are identifiable in an affected joint's fluid. (medicinenet.com)
Fibromyalgia is a form of arthritis characterized by long-lasting and widespread tenderness and pain at specific points on the body. (jointhealthmagazine.com)
Typically, this form of arthritis is referred to as a syndrome because it involves a set of symptoms and signs that occur together without a known cause. (jointhealthmagazine.com)
Osteoporosis refers to a form of arthritis that causes your bones to become fragile. (jointhealthmagazine.com)
According to the Centers for Disease Control and Prevention (CDC[1]), approximately 22,7% of people in the U.S. were told by a doctor to have some form of arthritis. (consumerhealthdigest.com)

After the disease, after a certain period of time, children have the phenomenon of post-infectious arthritis. (medicalj-center.info)
Post-infectious arthritis. (cdc.gov)
About 2% 1-4 of people who are infected with the type of Shigella called Shigella flexneri will experience post-infectious arthritis, which causes joint pains, eye irritation, and painful urination. (cdc.gov)
Post-infectious arthritis usually does not occur in people who get sick from the other types of Shigella, called S. sonnei 8 , 9 , S. boydii, or S. dystenteriae 10 . (cdc.gov)

What Causes Infectious Arthritis? (healthcommunities.com)

People with HIV are at increased risk for non-infectious complications, including cardiovascular disease. (nih.gov)

If you have high fever along with severe joint pain, it may be infectious arthritis (also called viral arthritis). (blogspot.com)
See Viral Arthritis . (merckvetmanual.com)

After the fourth course the patient presented to our clinic for fever with chills, pollakiuria, hematuria, conjunctivitis, myalgia and disabling migratory arthritis of the left ankle and right knee. (biomedcentral.com)

The diagnosis of infectious arthritis depends on a combination of laboratory testing with careful history-taking and physical examination of the affected joint. (encyclopedia.com)
Prompt diagnosis of infectious arthritis is necessary to prevent permanent damage to the joint. (nyhq.org)
It was determined by an ROC curve that a determination of PCT higher or equal than 1.475 established the diagnosis of infectious arthritis with a sensitivity of 100% and a specificity of 88.89% (Likelihood ratio 9.00). (bmj.com)
Diagnosis of infectious arthritis requires the aspiration of a small quantity of synovial fluid from the afflicted joint. (chromoscience.com)

Common arthritis joint symptoms include swelling, pain, stiffness and decreased range of motion. (arthritis.org)

These details may help to differentiate infectious arthritis from some other inflammatory or arthritic condition. (vetinfo.com)
In this article, we look at the symptoms of arthritis in the toes, the different types of arthritis, and how a person can find relief from arthritic pain and discomfort. (medicalnewstoday.com)
If your physician suspects that you may have an infectious arthritic joint they will require a sample of the fluid which is removed with a sterile needle as soon as possible. (reliawire.com)

Infectious arthritis can occur in any age group, including newborns and children. (encyclopedia.com)
This infectious arthritis can occur within days or weeks after the symptoms of gonorrhea appear. (washington.edu)
These imaging tests are better than x-rays at showing early changes that can occur with a number of types of infectious arthritis. (emedtv.com)

Additional evidence for the infectious etiology of human RA was recently presented by Gottlieb et al (12), who demonstrated that prior to onset of arthritis COLE ET AL 436 Table 1. (docme.ru)

After 2 months of antiTB, glucocorticoid and sulfasalazine treatment the evolution was favorable, with remission of arthritis and fever. (biomedcentral.com)
and naproxen naproxen and naproxen sodium, potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever. (thefreedictionary.com)

Anatomy49

Organisms12

Diseases51

Chemicals and Drugs81

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Psychiatry and Psychology2

Phenomena and Processes19

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena4

Humanities1

Information Science2

Health Care24

Alpha-toxin and gamma-toxin jointly promote Staphylococcus aureus virulence in murine septic arthritis. (1/959)

Genetic control of experimental lyme arthritis in the absence of specific immunity. (2/959)

Osteonecrosis of the hip in sickle-cell disease associated with tuberculous arthritis. A review of 15 cases. (3/959)

Longitudinal and cross-sectional variability in markers of joint metabolism in patients with knee pain and articular cartilage abnormalities. (4/959)

IL-1beta, IL-6 and TNF-alpha in synovial fluid of patients with non-gonococcal septic arthritis. (5/959)

Slipped capital femoral epiphysis after septic arthritis of the hip in an adolescent: report of a case. (6/959)

Gamma interferon and interleukin-10 gene expression in synovial tissues from patients with early stages of Chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers. (7/959)

Development of lyme arthritis in mice deficient in inducible nitric oxide synthase. (8/959)

Arthritis, Rheumatoid

Arthritis

Arthritis, Experimental

Arthritis, Infectious

Arthritis, Juvenile

Arthritis, Psoriatic

Arthritis, Reactive

Synovial Membrane

Joints

Synovial Fluid

Arthritis, Gouty

Rheumatoid Factor

Mice, Inbred DBA

Synovitis

Osteoarthritis

Collagen Type II

Methotrexate

Severity of Illness Index

Rats, Inbred Lew

Autoantibodies

Blood Sedimentation

Injections, Intra-Articular

Tumor Necrosis Factor-alpha

Rheumatic Diseases

Immunoglobulin G

Arthrography

Rheumatology

Knee Joint

Metacarpophalangeal Joint

Spondylitis, Ankylosing

Sulfasalazine

Peptides, Cyclic

Autoimmune Diseases

Antibodies, Monoclonal

Gold Sodium Thiomalate

Wrist Joint

Rheumatoid Nodule

Collagen

HLA-DRB1 Chains

Finger Joint

Disease Models, Animal

Treatment Outcome

Tarsal Joints

Lyme Disease

Receptors, Tumor Necrosis Factor

HLA-DR4 Antigen

Anti-Inflammatory Agents

Joint Diseases

HLA-DR Antigens

Citrulline

Cytokines

Spondylarthropathies

Foot Joints

Psoriasis

Cartilage, Articular

Ankle Joint

Inflammation

T-Lymphocytes

Interleukin-17

Edema

Freund's Adjuvant

Tarsus, Animal

Enzyme-Linked Immunosorbent Assay

Tenosynovitis

HLA-B27 Antigen

Biological Markers

Organogold Compounds

Drug Therapy, Combination

Hand Joints

Glucose-6-Phosphate Isomerase

Disability Evaluation

Pain

Lupus Erythematosus, Systemic

Cells, Cultured

Interleukin-6

Chronic Disease

Interleukin-1

Genetic Predisposition to Disease

Interleukin 1 Receptor Antagonist Protein

Cartilage