Arterivirus
A genus of the family ARTERIVIRIDAE, in the order NIDOVIRALES. The type species is ARTERITIS VIRUS, EQUINE.
Arteritis Virus, Equine
Porcine respiratory and reproductive syndrome virus
Nidovirales
An order comprising three families of eukaryotic viruses possessing linear, nonsegmented, positive sense RNA genomes. The families are CORONAVIRIDAE; ARTERIVIRIDAE; and RONIVIRIDAE.
Arteriviridae
A family of viruses, of the order NIDOVIRALES, containing spherical virions. In contrast to CORONAVIRIDAE, no protruding spikes are obvious on the surface.
Lactate dehydrogenase-elevating virus
Porcine Reproductive and Respiratory Syndrome
A syndrome characterized by outbreaks of late term abortions, high numbers of stillbirths and mummified or weak newborn piglets, and respiratory disease in young unweaned and weaned pigs. It is caused by PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS. (Radostits et al., Veterinary Medicine, 8th ed, p1048)
RNA Replicase
Open Reading Frames
Viral Nonstructural Proteins
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
Virus Replication
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
Genome, Viral
The complete genetic complement contained in a DNA or RNA molecule in a virus.
Horses
Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.
Cricetinae
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Fatigue
Databases, Protein
Viral Envelope Proteins
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
Cimicidae
Adaptive Immunity
Protection from an infectious disease agent that is mediated by B- and T- LYMPHOCYTES following exposure to specific antigen, and characterized by IMMUNOLOGIC MEMORY. It can result from either previous infection with that agent or vaccination (IMMUNITY, ACTIVE), or transfer of antibody or lymphocytes from an immune donor (IMMUNIZATION, PASSIVE).
Encyclopedias as Topic
MedlinePlus
Aging
Internet
Wounds, Gunshot
Consumer Health Information
Social Media
Platforms that provide the ability and tools to create and publish information accessed via the INTERNET. Generally these platforms have three characteristics with content user generated, high degree of interaction between creator and viewer, and easily integrated with other sites.
Nucleic Acids
Nucleic Acid Hybridization
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
DNA Probes
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
DNA
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Oligonucleotide Probes
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
Terminology as Topic
Indigo Carmine
Classification
Red Cross
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
Vanilla
Paeonia
A plant genus of the family Paeoniaceae, order Dilleniales, subclass Dilleniidae, class Magnoliopsida. These perennial herbs are up to 2 m (6') tall. Leaves are alternate and are divided into three lobes, each lobe being further divided into three smaller lobes. The large flowers are symmetrical, bisexual, have 5 sepals, 5 petals (sometimes 10), and many stamens.
Hepatitis, Infectious Canine
A contagious disease caused by canine adenovirus (ADENOVIRUSES, CANINE) infecting the LIVER, the EYE, the KIDNEY, and other organs in dogs, other canids, and bears. Symptoms include FEVER; EDEMA; VOMITING; and DIARRHEA.
Dog Diseases
Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Cell Division
Dogs
Data Collection
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Luciferases, Renilla
Luciferases from RENILLA that oxidizes certain LUMINESCENT AGENTS to cause emission of PHOTONS.
Renilla
A genus of bioluminescent marine invertebrates in the family Renillidae, order Pennatulacea, class ANTHOZOA. It contains Renilla LUCIFERASE which oxidizes coelenterazine resulting in LUMINESCENCE.
Arterivirus discontinuous mRNA transcription is guided by base pairing between sense and antisense transcription-regulating sequences. (1/55)
To generate an extensive set of subgenomic (sg) mRNAs, nidoviruses (arteriviruses and coronaviruses) use a mechanism of discontinuous transcription. During this process, mRNAs are generated that represent the genomic 5' sequence, the so-called leader RNA, fused at specific positions to different 3' regions of the genome. The fusion of the leader to the mRNA bodies occurs at a short, conserved sequence element, the transcription-regulating sequence (TRS), which precedes every transcription unit in the genome and is also present at the 3' end of the leader sequence. Here, we have used site-directed mutagenesis of the infectious cDNA clone of the arterivirus equine arteritis virus to show that sg mRNA synthesis requires a base-pairing interaction between the leader TRS and the complement of a body TRS in the viral negative strand. Mutagenesis of the body TRS of equine arteritis virus RNA7 reduced sg RNA7 transcription severely or abolished it completely. Mutations in the leader TRS dramatically influenced the synthesis of all sg mRNAs. The construction of double mutants in which a mutant leader TRS was combined with the corresponding mutant RNA7 body TRS resulted in the specific restoration of mRNA7 synthesis. The analysis of the mRNA leader-body junctions of a number of mutants with partial transcriptional activity provided support for a mechanism of discontinuous minus-strand transcription that resembles similarity-assisted, copy-choice RNA recombination. (+info)Gill-associated virus of Penaeus monodon prawns: an invertebrate virus with ORF1a and ORF1b genes related to arteri- and coronaviruses. (2/55)
A 20089 nucleotide (nt) sequence was determined for the 5' end of the (+)-ssRNA genome of gill-associated virus (GAV), a yellow head-like virus infecting Penaeus monodon prawns. Clones were generated from a approximately 22 kb dsRNA purified from lymphoid organ total RNA of GAV-infected prawns. The region contains a single gene comprising two long overlapping open reading frames, ORF1a and ORF1b, of 4060 and 2646 amino acids, respectively. The ORFs are structurally related to the ORF1a and ORF1ab polyproteins of coronaviruses and arteriviruses. The 99 nt overlap between ORF1a and ORF1b contains a putative AAAUUUU 'slippery' sequence associated with -1 ribosomal frameshifting. A 131 nt stem-loop with the potential to form a complex pseudoknot resides 3 nt downstream of this sequence. Although different to the G/UUUAAAC frameshift sites and 'H-type' pseudoknots of nidoviruses, in vitro transcription/translation analysis demonstrated that the GAV element also facilitates read-through of the ORF1a/1b junction. As in coronaviruses, GAV ORF1a encodes a 3C-like cysteine protease domain located between two hydrophobic regions. However, its sequence suggests some structural relationship to the chymotrypsin-like serine proteases of arteriviruses. ORF1b encodes homologues of the 'SDD' polymerase, which among (+)-RNA viruses is unique to nidoviruses, as well as metal-ion-binding and helicase domains. The presence of a dsRNA replicative intermediate and ORF1a and ORF1ab polyproteins translated by a-1 frameshift suggests that GAV represents the first invertebrate member of the Order NIDOVIRALES: (+info)The arterivirus replicase is the only viral protein required for genome replication and subgenomic mRNA transcription. (3/55)
Equine arteritis virus (EAV) (ARTERIVIRIDAE:) encodes several structural proteins. Whether any of these also function in viral RNA synthesis is unknown. For the related mouse hepatitis coronavirus (MHV), it has been suggested that the nucleocapsid protein (N) is involved in viral RNA synthesis. As described for MHV, we established that the EAV N protein colocalizes with the viral replication complex, suggesting a role in RNA synthesis. Using an infectious cDNA clone, point mutations and deletions were engineered in the EAV genome to disrupt the expression of each of the structural genes. All structural proteins, including N, were found to be dispensable for genome replication and subgenomic mRNA transcription. We also constructed a mutant in which translation of the intraleader ORF was disrupted. This mutant had a wild-type phenotype, indicating that, at least in cell culture, the product of this ORF does not play a role in the EAV replication cycle. (+info)Biochemical characterization of the equine arteritis virus helicase suggests a close functional relationship between arterivirus and coronavirus helicases. (4/55)
The arterivirus equine arteritis virus nonstructural protein 10 (nsp10) has previously been predicted to contain a Zn finger structure linked to a superfamily 1 (SF1) helicase domain. A recombinant form of nsp10, MBP-nsp10, was produced in Escherichia coli as a fusion protein with the maltose-binding protein. The protein was partially purified by affinity chromatography and shown to have ATPase activity that was strongly stimulated by poly(dT), poly(U), and poly(dA) but not by poly(G). The protein also had both RNA and DNA duplex-unwinding activities that required the presence of 5' single-stranded regions on the partial-duplex substrates, indicating a 5'-to-3' polarity in the unwinding reaction. Results of this study suggest a close functional relationship between the arterivirus nsp10 and the coronavirus helicase, for which NTPase and duplex-unwinding activities were recently demonstrated. In a number of biochemical properties, both arterivirus and coronavirus SF1 helicases differ significantly from the previously characterized RNA virus SF1 and SF2 enzymes. Thus, the combined data strongly support the idea that nidovirus helicases may represent a separate group of RNA virus-encoded helicases with distinct properties. (+info)Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole. (5/55)
Arteriviruses are enveloped, positive-stranded RNA viruses and include pathogens of major economic concern to the swine- and horse-breeding industries. The arterivirus replicase gene encodes two large precursor polyproteins that are processed by the viral main proteinase nonstructural protein 4 (nsp4). The three-dimensional structure of the 21-kDa nsp4 from the arterivirus prototype equine arteritis virus has been determined to 2.0 A resolution. Nsp4 adopts the smallest known chymotrypsin-like fold with a canonical catalytic triad of Ser-120, His-39, and Asp-65, as well as a novel alpha/beta C-terminal extension domain that may play a role in mediating protein-protein interactions. In different copies of nsp4 in the asymmetric unit, the oxyanion hole adopts either a collapsed inactive conformation or the standard active conformation, which may be a novel way of regulating proteolytic activity. (+info)Chimeric arteriviruses generated by swapping of the M protein ectodomain rule out a role of this domain in viral targeting. (6/55)
Arteriviruses are enveloped, positive-strand RNA viruses for which the two major envelope proteins GP(5) and M occur as disulfide-linked heterodimers. These were assumed to serve the viral targeting functions, but recent ectodomain swapping studies with equine arteritis virus (EAV) indicate that the GP(5) protein does not determine arteriviral tropism. Here, we focused on the short, 13- to 18-residue ectodomain of the M protein. Using an infectious cDNA clone of the Lelystad virus isolate of porcine reproductive and respiratory syndrome virus (PRRSV), we substituted the genomic sequence encoding the M ectodomain by that of murine lactate dehydrogenase-elevating virus, EAV, and the US PRRSV-isolate, VR2332. Viable viruses with a chimeric M protein were obtained in all three cases, but for the latter two only after removal of the genomic overlap between the M and GP(5) genes. Characterization of the chimeric viruses revealed that they could be distinguished immunologically from wild-type virus, that they were genetically stable in vitro, but that they were impaired in their growth, reaching lower titers than the parental virus. The latter appeared to be due to an increased particle-to-infectivity ratio of the chimeric virus particles. Interestingly, the chimeric viruses had retained their ability to infect porcine cells and had not acquired tropism for cells susceptible to the viruses from which the foreign ectodomains were derived. We conclude that the surface structures composed by the arterivirus M and GP(5) ectodomains do not determine viral tropism. (+info)Quantitative assessment of the effect of uracil-DNA glycosylase on amplicon DNA degradation and RNA amplification in reverse transcription-PCR. (7/55)
Although PCR and RT-PCR provided a valuable approach for detection of pathogens, the high level of sensitivity of these assays also makes them prone to false positive results. In addition to cross-contamination with true positive samples, false positive results are also possible due to "carry-over" contamination of samples with amplicon DNA generated by previous reactions. To reduce this source of false positives, amplicon generated by reactions in which dUTP was substituted for dTTP can be degraded by uracil DNA glycosylase (UNG). UNG does not degrade RNA but will cleave contaminating uracil-containing DNA while leaving thymine-containing DNA intact. The availability of heat-labile UNG makes use of this approach feasible for RT-PCR. In this study, real-time RT-PCR was used to quantify UNG degradation of amplicon DNA and the effect of UNG on RNA detection. Using the manufacturers' recommended conditions, complete degradation of DNA was not observed for samples containing 250 copies of amplicon DNA. Doubling the UNG concentration resulted in degradation of the two lowest concentrations of DNA tested, but also resulted in an increase of 1.94 cycles in the CT for RNA detection. To improve DNA degradation while minimizing the effect on RNA detection, a series of time, temperature and enzyme concentrations were evaluated. Optimal conditions were found to be 0.25 U UNG per 25 microl reaction with a 20 min, 30 degrees C incubation prior to RT-PCR. Under these conditions, high concentrations of amplicon DNA could be degraded while the CT for RNA detection was increased by 1.2 cycles. (+info)An RNA pseudoknot in the 3' end of the arterivirus genome has a critical role in regulating viral RNA synthesis. (8/55)
In the life cycle of plus-strand RNA viruses, the genome initially serves as the template for both translation of the viral replicase gene and synthesis of minus-strand RNA and is ultimately packaged into progeny virions. These various processes must be properly balanced to ensure efficient viral proliferation. To achieve this, higher-order RNA structures near the termini of a variety of RNA virus genomes are thought to play a key role in regulating the specificity and efficiency of viral RNA synthesis. In this study, we have analyzed the signals for minus-strand RNA synthesis in the prototype of the arterivirus family, equine arteritis virus (EAV). Using site-directed mutagenesis and an EAV reverse genetics system, we have demonstrated that a stem-loop structure near the 3' terminus of the EAV genome is required for RNA synthesis. We have also obtained evidence for an essential pseudoknot interaction between the loop region of this stem-loop structure and an upstream hairpin residing in the gene encoding the nucleocapsid protein. We propose that the formation of this pseudoknot interaction may constitute a molecular switch that could regulate the specificity or timing of viral RNA synthesis. This hypothesis is supported by the fact that phylogenetic analysis predicted the formation of similar pseudoknot interactions near the 3' end of all known arterivirus genomes, suggesting that this interaction has been conserved in evolution. (+info)
rep - Replicase polyprotein 1ab - Simian hemorrhagic fever virus (SHFV) - rep gene & protein
Equestrian OutreachEquine Viral Arteritis Page
ASMscience | The Arterivirus Replicas
Increased pathology during infection with an atypical European porcine Arterivirus correlates with an enhanced adaptive immune...
Arterivirus GP4 envelope glycoprotein (IPR003412) | InterPro | EMBL-EBI
Quercetin and Zinc: Our Allies in Fighting Viruses
Discount forex Rjukan
RCSB PDB
- 1MBM: NSP4 proteinase from Equine Arteritis Virus Literature Report Page
Português
Nederlands
DNA Replication & Transcription Antibodies | EpiGentek
Estudio de la excreción y transmisión del aislado chileno del virus del síndrome respiratorio y reproductivo porcino (PRRS) en...
Nucleic Acids Essay - 1383 Words | AntiEssays
First quinoa sown - WUR
Niki Terpstra in intensive care after training crash | Cycling Today
IJMS | Free Full-Text | Genetic Diversity Characterization of Porcine Reproductive and Respiratory Syndrome Virus Isolates in...
Antigenic and genetic variations of the 15 kD nucleocapsid protein of porcine reproductive and respiratory syndrome virus...
4 Genetic diversity of the PRRS virus
Sequence Similarity
- 4IUM: Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin...
Viruses | Free Full-Text | Replication-Competent Recombinant Porcine Reproductive and Respiratory Syndrome (PRRS) Viruses...
EAV Bucyrus antigen Shirley - Science Marketplace
Biochemical properties and processing of the three major structural proteins of PRRS virus expressed by recombinant...
Alternative codon usage of PRRS virus ORF5 gene increases eucaryotic expression of GP5 glycoprotein and improves immune...
Alternative codon usage of PRRS virus ORF5 gene increases eucaryotic expression of GP5 glycoprotein and improves immune...
Publications - Institute for Bioengineering of Catalonia (IBEC)
Publications - Institute for Bioengineering of Catalonia (IBEC)
Amino acid substitutions in the structural or nonstructural proteins of a vaccine strain of equine arteritis virus are...
Heterogeneous antigenic properties of the porcine reproductive and respiratory syndrome virus nucleocapsid | Veterinary...
Comparison of M and N gene sequences distinguishes variation amongst equine arteritis virus isolates | Microbiology Society
Equine arteritis virus replication in monocytic cells suppresses differentiation and function of dendritic cells - Surrey...
Lelystad Airport (LEY) News Room - Latest news and breaking stories - Aviation24.be
ALZFORUM | NETWORKING FOR A CURE
Abstract: Dee SA. 1996;4(4):181-184 Detecting subpopulations after PRRS virus infection in large bre
Terje Dokland
Sμ-Sα junction sequences. (A) Percentage of switch | Open-i
virotype PRRSV NA/EU RT-PCR Rgt - QIAGEN Online Shop
Detection of equine arteritis virus by real-time TaqMan® reverse transcription-PCR assay<...
Equine Arteritis Virus Uses Equine CXCL16 as an Entry Receptor by Sanjay Sarkar, Lakshman Chelvarajan et al.
Structure and function of replicative proteins from alphaviruses | EUVIRNA
anti-GP 3 of Porcine reproductive and respiratory syndrome virus (PRRSV), clone Hy P10-c40-c1 (CCLV-RIE 1167) | EVAg
NC229: Detection and Control of Porcine Reproductive and Respiratory Syndrome Virus and Emerging Viral Diseases of Swine
...
Laboratory Investigation of PRRS Virus Infection in Three Swine Herds - The Pig Site
動物疾病研究報告行動知識家
Journal News: MCP: Using hamsters to study hemorrhagic fever
Genetic variant determines if stallions become carriers of equine arteritis virus | EurekAlert! Science News
The open reading frame 3 of equine arteritis virus encodes an immunogenic glycosylated, integral membrane protein. - PubMed -...
Cloning, expression, and sequence analysis of the ORF4 gene of the porcine reproductive and respiratory syndrome virus MN-1b -...
Jianqiang Zhang | College of Veterinary Medicine
Jianqiang Zhang | College of Veterinary Medicine
Identification of Neutralizing and Nonneutralizing Epitopes in the Porcine Reproductive and Respiratory Syndrome Virus GP5...
Hemorrhagic Fever Viruses (HFVs)
Swine Farms - AAF International
Development of PRRSv-Resistant Hogs a Critical Scientific Breakthrough
The A - Z Of Aol Mail Inbox | Kerala State Poultry Development Corporation
Related changes
m Arterivirus; 13:12 . . (+13) . . . Tom.Reding. (talk , contribs) (Add from=Q707854 to {{Taxonbar}}; WP:GenFixes on, using ...
Positive-sense single-stranded RNA virus
All but the arterivirus family contain at least one human pathogen; arteriviruses are known only as animal pathogens. Many ...
Virus
In 1957, equine arterivirus and the cause of Bovine virus diarrhoea (a pestivirus) were discovered. In 1963, the hepatitis B ...
Nidovirales
Animal viruses RNA viruses Coronavirus Arterivirus Luis Enjuanes, Isabel Sola, Sonia Zúñiga and Fernando Almazán (2008). " ...
Diferenzas entre revisións de «Virus de ARN», a enciclopedia libre
arterivirus. . The. Os. coronaviruses. coronavirus. and. e. toroviruses. torovirus. appear. parecen. to. ser. be. familias. ...
History of virology
... equine arterivirus was discovered. In the 1950s, improvements in virus isolation and detection methods resulted in the ...
Taxonomic list of viruses
Arterivirus Equine arteritis virus Lactate dehydrogenase-elevating virus Porcine reproductive and respiratory syndrome virus ...
List of MeSH codes (B04)
... arterivirus MeSH B04.820.504.080.100.100 --- arteritis virus, equine MeSH B04.820.504.080.100.500 --- lactate dehydrogenase- ... arterivirus MeSH B04.909.777.500.080.500.100 --- arteritis virus, equine MeSH B04.909.777.500.080.500.500 --- lactate ...
List of genera of viruses
Anulavirus Aparavirus Aphthovirus Apscaviroid Aquabirnavirus Aquamavirus Aquaparamyxovirus Aquareovirus Arterivirus Ascovirus ...
List of MeSH codes (C02)
... arterivirus infections MeSH C02.782.600.100.700 --- porcine reproductive and respiratory syndrome MeSH C02.782.600.550 --- ...
List of EC numbers (EC 3)
... equine arterivirus serine peptidase EC 3.4.21.115: infectious pancreatic necrosis birnavirus Vp4 peptidase EC 3.4.21.116: ...
List of virus species
Flock House virus Florida wood cockroach cyclovirus Foot-and-mouth disease virus Forest pouched giant rat arterivirus Fort ... virus Datura leaf distortion virus Datura shoestring virus Datura yellow vein nucleorhabdovirus DeBrazza's monkey arterivirus ...
Arterivirus
... at the US National Library of Medicine Medical Subject Headings (MeSH) ICTVdb Animal viruses Viralzone: Arterivirus ... Arterivirus is the only genus of viruses in the family Arteriviridae, which is within the order Nidovirales. Vertebrates serve ... These proposals would abolish the genus Arterivirus and create five new genera: Dipartevirus, Equartevirus, Nesartevirus, ... Viruses in Arterivirus are enveloped, with spherical, Round, and Isometric geometries. The diameter is around 45-60 nm. Genomes ...
Equine arterivirus serine peptidase
... in arterivirus replicase translation products ORF1a and ORF1ab In the equine arterivirus (EAV), the replicase gene is ... Equine arterivirus serine peptidase (EC 3.4.21.114) is an enzyme. This enzyme catalyses the following chemical reaction ... Equine arterivirus serine peptidase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... "The arterivirus nsp4 protease is the prototype of a novel group of chymotrypsin-like enzymes, the 3C-like serine proteases". J ...
Category:Low-importance virus articles
Talk:Arterivirus. *Talk:Artichoke Italian latent virus. *Talk:Asama virus. *Talk:Astrovirus ...
Category:EC 3.4.21
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization ...
腸道病毒 - 维基百科，自由的百科全书
Arterivirus（英语：Arterivirus）. *冠状病毒科 Coronaviridae. *Roniviridae（英语：Roniviridae） ...
中東呼吸綜合症 - 维基百科，自由的百
Arterivirus（英语：Arterivirus）. *冠状病毒科 Coronaviridae. *Roniviridae（英语：Roniviridae） ...
Arterivirus GP4 envelope glycoprotein (IPR003412) | InterPro | EMBL-EBI
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
ASMscience | The Arterivirus Replicas
This chapter focuses on the arterivirus proteins that are involved in genome replication and subgenomic RNA (sgRNA) synthesis. ... Comparison of arterivirus replicase gene features. Citation: van Hemert M, Snijder E. 2008. The Arterivirus Replicase, p 83-101 ... Molenkamp, R.,, H. van Tol,, B. C. Rozier,, Y. van der Meer,, W. J. Spaan, and, E. J. Snijder. 2000. The arterivirus replicase ... Snijder, E. J.,, A. L. Wassenaar,, L. C. van Dinten,, W. J. Spaan, and, A. E. Gorbalenya. 1996. The arterivirus nsp4 protease ...
Increased pathology during infection with an atypical European porcine Arterivirus correlates with an enhanced adaptive immune...
rep - Replicase polyprotein 1ab - Simian hemorrhagic fever virus (SHFV) - rep gene & protein
Equestrian OutreachEquine Viral Arteritis Page
Equine viral arteritis (EVA) is a disease of horses caused by an RNA virus of the genus Arterivirus. The virus which causes EVA ...
Quercetin and Zinc: Our Allies in Fighting Viruses
Arterivirus - Wikipedia
Arterivirus at the US National Library of Medicine Medical Subject Headings (MeSH) ICTVdb Animal viruses Viralzone: Arterivirus ... Arterivirus is the only genus of viruses in the family Arteriviridae, which is within the order Nidovirales. Vertebrates serve ... These proposals would abolish the genus Arterivirus and create five new genera: Dipartevirus, Equartevirus, Nesartevirus, ... Viruses in Arterivirus are enveloped, with spherical, Round, and Isometric geometries. The diameter is around 45-60 nm. Genomes ...
Equine arterivirus serine peptidase - Wikipedia
... in arterivirus replicase translation products ORF1a and ORF1ab In the equine arterivirus (EAV), the replicase gene is ... Equine arterivirus serine peptidase (EC 3.4.21.114) is an enzyme. This enzyme catalyses the following chemical reaction ... Equine arterivirus serine peptidase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... "The arterivirus nsp4 protease is the prototype of a novel group of chymotrypsin-like enzymes, the 3C-like serine proteases". J ...
arterivirus | Journal of Virology
Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 - Volume 27, Number 2...
We used next-generation sequencing to identify a novel arterivirus with a genome coding sequence of only 43% similarity to ... Vanmechelen B, Vergote V, Laenen L, Koundouno FR, Bore JA, Wada J, et al. Expanding the arterivirus host spectrum: Oliviers ... Arterivirus molecular biology and pathogenesis. J Gen Virol. 2013;94:2141-63. DOIPubMed ... Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 On This Page ...
Figure 1 - Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 - Volume 27,...
We used next-generation sequencing to identify a novel arterivirus with a genome coding sequence of only 43% similarity to ... Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 Akbar Dastjerdi. , Nadia ... Phylogenetic analysis of the coding sequence of hedgehog arterivirus 1. The virus genome was aligned by using the MegAlign ... Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019. ...
Heterodimerization of the Two Major Envelope Proteins Is Essential for Arterivirus Infectivity | Journal of Virology
Arterivirus particles are enveloped and have a diameter of 40 to 60 nm. The virion probably contains a set of seven structural ... The arterivirus genome contains a large 5′-proximal replicase gene (ORF1a plus ORF1b) that is translated from the genome RNA. ... The isometric arterivirus nucleocapsid is composed of the RNA genome and a small nucleocapsid protein (N; 110 to 128 amino ... The arterivirus replicase is the only viral protein required for genome replication and subgenomic mRNA transcription. J. Gen. ...
Add your annotation to InterPro | InterPro | EMBL-EBI
Arteriviridae | IVIS
Arterivirus. Equine Viral Arteritis. Cause. Equine arteritis virus.. Occurrence. Hosts are horses, donkeys and mules. Equine ... An arterivirus. Antigenic differences have been noted among different isolates. Three different genotypes have been identified ... It has only one genus, Arterivirus, whose virus species are antigenically distinct from each other. ...
Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these...
Animals, Arterivirus, Arterivirus Infections, Blotting, Western, Cercopithecus aethiops, Electrophoretic Mobility Shift Assay, ... Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these ... Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these ...
Related changes - Wikipedia
Patent US20030152942 - Nucleic acid detection in pooled samples - Google Patents
"Arterivirus". (a floating genus). nonenveloped. Astroviridae. Caliciviridae. Picornaviridae. Potyviridae. DNA step in ...
Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses, Book by Andrew MQ King (Other) | chapters...
The Springer Index of Viruses | SpringerLink
The continuous growth of knowledege makes it very difficult for scientists to retrieve comprehensive and accurate data on viruses. The desired information is often dispersed in a variety of books, jou
Kay Faaberg : USDA ARS
Arterivirus structural proteins and assembly - Faaberg, K.S. 2007. Arterivirus structural proteins and assembly. In: Perlman, S ... Arterivirus: 03.004.0.01.002. Simian hemorrhagic fever virus. In: A.J. Davison, et al. (chair), Vertebrate Virus Subcommittee. ... Arterivirus: 03.004.0.01.003. Lactate dehydrogenase elevating virus. In: A.J. Davison, et al. (chair), Vertebrate Virus ...
Viruses | Free Full-Text | Replication-Competent Recombinant Porcine Reproductive and Respiratory Syndrome (PRRS) Viruses...
Publikationen • Institut für Virologie • Fachbereich Veterinärmedizin
The Big Picture Book of Viruses - Baltimore Listing
Figure 2 - Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 - Volume 27,...
We used next-generation sequencing to identify a novel arterivirus with a genome coding sequence of only 43% similarity to ... Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 Akbar Dastjerdi. , Nadia ... Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019. ... Genomic organization of hedgehog arterivirus-1. The genome arrangement resembles those of classical arteriviruses with open ...
Diferenzas entre revisións de «Virus de ARN» - Wikipedia, a enciclopedia libre
USDA APHIS | Horse Disease Information
Frontiers | Direct Interaction Between CD163 N-Terminal Domain and MYH9 C-Terminal Domain Contributes to Porcine Reproductive...
RNA structures regulating nidovirus RNA synthesis
Virology
Viruses | Free Full-Text | Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein | Notes
Mice and Rats as Laboratory Animals - Exotic and Laboratory Animals - Merck Veterinary Manual
Publications | Max Planck Institute of Biochemistry
"Arterivirus papain-like proteinase 1α". Handbook of Proteolytic Enzymes. Oxford: Academic Press, pp. 2199-2204. ... "Arterivirus papain-like proteinase 1β". Handbook of Proteolytic Enzymes. Oxford: Academic Press, pp. 2205-2210. ... "Arterivirus nsp1 modulates the accumulation of minus-strand templates to control the relative abundance of viral mRNAs". PLoS ... "Arterivirus subgenomic mRNA synthesis and virion biogenesis depend on the multifunctional nsp1 autoprotease". J Virol. 81 (19 ...
Porcine arterivirus2
- Little is known for such regulatory elements controlling porcine arterivirus replication. (nih.gov)
- Porcine arterivirus attachment to the macrophage-specific receptor sialoadhesin is dependent on the sialic81, 9546-9550 (2007). (functionalglycomics.org)
Arteritis virus1
- Group: ssRNA(+) Order: Nidovirales Family: Arteriviridae Genus: Arterivirus Equine arteritis virus Lactate dehydrogenase-elevating virus Porcine reproductive and respiratory syndrome virus Simian hemorrhagic fever virus Viruses in Arterivirus are enveloped, with spherical, Round, and Isometric geometries. (wikipedia.org)
Equine4
- Equine arterivirus serine peptidase (EC 3.4.21.114) is an enzyme. (wikipedia.org)
- This enzyme catalyses the following chemical reaction Cleavage of (Glu/Gln)-(Gly/Ser/Ala) in arterivirus replicase translation products ORF1a and ORF1ab In the equine arterivirus (EAV), the replicase gene is translated into open reading frame 1a (ORF1a) and ORF1ab [polyprotein]s. (wikipedia.org)
- Equine Viral Arteritis (EVA) is caused by arterivirus. (usda.gov)
- In the equine arterivirus (EAV), the replicase gene is translated into open reading frame 1a (ORF1a) and ORF1ab polyproteins. (expasy.org)
Genome7
- We used next-generation sequencing to identify a novel arterivirus with a genome coding sequence of only 43% similarity to existing GenBank arterivirus sequences. (cdc.gov)
- The arterivirus genome is composed of a single, 12-16 kb, polyadenylated, RNA strand that contains 2 major genomic regions. (cdc.gov)
- We describe the disease history, histopathology, and the near complete genome sequence of a novel arterivirus, hedgehog arterivirus 1 (HhAV-1). (cdc.gov)
- The arterivirus genome contains a large 5′-proximal replicase gene (ORF1a plus ORF1b) that is translated from the genome RNA. (asm.org)
- This chapter focuses on the arterivirus proteins that are involved in genome replication and subgenomic RNA (sgRNA) synthesis. (asmscience.org)
- These proteins, which are collectively referred to as "replicase/transcriptase" or-for simplicity-just "replicase," are encoded by open reading frames 1a and 1b (ORF1a and ORF1b) of the arterivirus genome. (asmscience.org)
- The arterivirus replicase gene covers approximately 75% of the genome. (asmscience.org)
Genus6
- Arterivirus is the only genus of viruses in the family Arteriviridae, which is within the order Nidovirales. (wikipedia.org)
- These proposals would abolish the genus Arterivirus and create five new genera: Dipartevirus, Equartevirus, Nesartevirus, Rodartevirus and Simartevirus. (wikipedia.org)
- It has only one genus, Arterivirus , whose virus species are antigenically distinct from each other. (ivis.org)
- The PRRSV belongs to the order Nidovirales, family Arteriviridae, genus Arterivirus [ 1 ]. (hindawi.com)
- The PRRS virus is an enveloped RNA virus in the genus Arterivirus, classified in the virus family, Arteriviridae. (iastate.edu)
- It is the prototype virus of the family Arteriviridae (genus Arterivirus, order Nidovirales) [4, 5]. (ukessays.com)
PRRS2
- PRRS is caused by an arterivirus. (pigprogress.net)
- PRRS is a highly contagious disease caused by a virus belonging to the Arterivirus family. (thermofisher.com)
Lactate Dehyd1
- In this article, we show that infection with lactate dehydrogenase-elevating virus, a benign mouse arterivirus, exacerbates the pathogenicity of IgM anti-platelet, but not anti-erythrocyte autoantibodies. (jimmunol.org)
Virology2
- Hij is voormalig Editor van the Journal of General Virology, lid van de Editorial Board van the Journal of Virology en Virus Research, en lid van de Adviescommissie van het Beijerinck Virologie Fonds. (lumc.nl)
- Voor het LUMC curriculum Biomedische Wetenschappen coördineert hij de master cursus "Molecular Virology of RNA viruses" en is hij betrokken in een aantal andere onderwijsactiviteiten. (lumc.nl)
Coding sequence2
- Phylogenetic analysis of the coding sequence of hedgehog arterivirus 1. (cdc.gov)
- Firth AE, Zevenhoven-Dobbe JC, Wills NM, Go YY, Balasuriya UB, Atkins JF, Snijder EJ, Posthuma CC (2011) Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production. (springer.com)
Hedgehog1
- Genomic organization of hedgehog arterivirus-1. (cdc.gov)
Nsp11
- The arterivirus nsp1 region contains a tandem of papain-like autoprotease domains (PCP α and PCP β ), and the arterivirus PCP α and PCP β domains were found to be active in the reticulocyte lysates and the E. coli systems [ 12 , 13 ]. (hindawi.com)
Infections1
- Regulatory T Cells in Arterivirus and Coronavirus Infections: Do They Protect Against Disease or Enhance it? (vt.edu)
Coronavirus1
- Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. (ox.ac.uk)
Replication2
- The chapter also talks about the properties of replicase subunits, and the arterivirus replication/transcription complex. (asmscience.org)
- The obtained knowledge of arterivirus RNA synthesis, formed the basis for an virus inhibitor study in which regulatory RNA sequences were targeted in an attempt to block virus replication in cell culture using phosphorodiamidate morpholino oligomers (P-PMOs). (leidenuniv.nl)
Nsp42
- Structure of arterivirus nsp4. (wikipedia.org)
- Arterivirus NSP4. (expasy.org)
SHFV3
- The two new SHFV variants, SHFV-krc1 and SHFV-krc2 are highly divergent from each other (51.9% nucleotide sequence identity) and from the SHFV type strain LVR 42-0/M6941 (52.0% and 51.8% nucleotide sequence identity, respectively) and demonstrate greater phylogenetic diversity within SHFV than has been documented within any other arterivirus. (nih.gov)
- They also demonstrate a degree of evolutionary divergence within SHFV that is roughly equivalent to the degree of divergence between other arterivirus species. (nih.gov)
- The presence of two such highly divergent SHFV variants co-infecting a single individual represents a degree of within-host viral diversity that exceeds what has previously been reported for any arterivirus. (nih.gov)
Virus3
- Op allerlei fronten is bovendien sprake van een moleculaire wapenwedloop tussen virus en gastheer, waarbij virussen er steeds weer in slagen cellulaire verdedigingsmechanismen te ontduiken of te ontregelen. (lumc.nl)
- The Porcine Respiratory and Reproductive Syndrome is caused by a virus and is categorised under arterivirus. (marketresearch.com)
- En este estudio evaluamos los fenotipos neutralizantes de las 5 únicas cepas de arteritis viral equina aisladas en Argentina y los comparamos con los de la cepa de referencia EAV-UCD por virus neutralización cruzada y análisis de secuencias aminoacídicas de las proteínas M y GP5. (bvsalud.org)
Envelope1
- Also, the nomenclature of arterivirus envelope glycoproteins has not yet been standardized. (asm.org)
Synthesis1
- In vitro transcription was performed using the Riboscribe RNA probe synthesis kit (TEBU, Le Perray-en-Yvelines, France) by adding the reaction mixture directly to the solid phase. (asm.org)
Life cycle1
- Proteolytic processing plays an important role during the arterivirus life cycle and presumably is a way to control the temporal and spatial release of replicase subunits. (asmscience.org)
Conserved domains1
- Comparative sequence analysis of the various prototypic arterivirus genomes, and comparison with more distantly related nidoviruses, led to the identification of a number of conserved domains within the replicase. (asmscience.org)
