Arteriviridae
Nidovirales
Arteritis Virus, Equine
Arterivirus
Site-directed mutagenesis of the Nidovirus replicative endoribonuclease NendoU exerts pleiotropic effects on the arterivirus life cycle. (1/2)
The highly conserved NendoU replicative domain of nidoviruses (arteriviruses, coronaviruses, and roniviruses) belongs to a small protein family whose cellular branch is prototyped by XendoU, a Xenopus laevis endoribonuclease involved in nucleolar RNA processing. Recently, sequence-specific in vitro endoribonuclease activity was demonstrated for the NendoU-containing nonstructural protein (nsp) 15 of several coronaviruses. To investigate the biological role of this novel enzymatic activity, we have characterized a comprehensive set of arterivirus NendoU mutants. Deleting parts of the NendoU domain from nsp11 of equine arteritis virus was lethal. Site-directed mutagenesis of conserved residues exerted pleiotropic effects. In a first-cycle analysis, replacement of two conserved Asp residues in the C-terminal part of NendoU rendered viral RNA synthesis and virus production undetectable. In contrast, mutagenesis of other conserved residues, including two putative catalytic His residues that are absolutely conserved in NendoU and cellular homologs, produced viable mutants displaying reduced plaque sizes (20 to 80% reduction) and reduced yields of infectious progeny of up to 5 log units. A more detailed analysis of these mutants revealed a moderate reduction in RNA synthesis, with subgenomic RNA synthesis consistently being more strongly affected than genome replication. Our data suggest that the arterivirus nsp11 is a multifunctional protein with a key role in viral RNA synthesis and additional functions in the viral life cycle that are as yet poorly defined. (+info)Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between corona- and arteriviridae. (2/2)
The causative agent of severe acute respiratory syndrome (SARS) is the SARS-associated coronavirus, SARS-CoV. The nucleocapsid (N) protein plays an essential role in SARS-CoV genome packaging and virion assembly. We have previously shown that SARS-CoV N protein forms a dimer in solution through its C-terminal domain. In this study, the crystal structure of the dimerization domain, consisting of residues 270-370, is determined to 1.75A resolution. The structure shows a dimer with extensive interactions between the two subunits, suggesting that the dimeric form of the N protein is the functional unit in vivo. Although lacking significant sequence similarity, the dimerization domain of SARS-CoV N protein has a fold similar to that of the nucleocapsid protein of the porcine reproductive and respiratory syndrome virus. This finding provides structural evidence of the evolutionary link between Coronaviridae and Arteriviridae, suggesting that the N proteins of both viruses have a common origin. (+info)
Arteriviridae
... is a family of enveloped, positive-strand RNA viruses in the order Nidovirales which infect vertebrates. Host ... "Chapter 25 - Arteriviridae and Roniviridae". Fenner's Veterinary Virology (Fifth ed.). Academic Press. 2017. pp. 463-476. doi: ... The family Arteriviridae contains the subfamilies: Crocarterivirinae Equarterivirinae Heroarterivirinae Simarterivirinae ... Variarterivirinae Zealarterivirinae "Arteriviridae ~ ViralZone". viralzone.expasy.org. Retrieved 17 June 2021. "Virus Taxonomy ...
Betaarterivirus
The genus is in the family Arteriviridae and order Nidovirales. The genus contains four subgenera and six species. Member ... Articles with 'species' microformats, Nidovirales, Arteriviridae, Virus genera). ...
Betaarterivirus suid 1
PRRSV is a member of the family Arteriviridae, and order Nidovirales. Other members of the family Arteriviridae include: equine ... The most conserved proteins within the whole family of Arteriviridae and PRRSV, in particular, are nsp9 (RNA-dependent RNA ... 10 November 2015). "In the family Arteriviridae create 10 species (1 unassigned, 9 in the genus Arterivirus) and rename one ... Nidovirales Arteriviridae Porartevirus Porcine reproductive and respiratory syndrome virus 1 0 M96262.2 Nidovirales ...
Variarterivirinae
The subfamily is in the family Arteriviridae and order Nidovirales. The subfamily contains three genera. Member viruses are ...
Porcine reproductive and respiratory syndrome virus 2
PRRSV is in the Arteriviridae family and the order Nidovirales. It has a positive sense RNA genome that is 15 kb long. This ... As a member of the family Arteriviridae, PRRSV has an in vivo and in vitro tropism for cells like macrophages or monocytes. ...
Nidovirales
The order includes the families Coronaviridae, Arteriviridae, Roniviridae, and Mesoniviridae. Member viruses have a viral ... a clade that includes the distantly related Arteriviridae (12.7-15.7 kb).[citation needed] The large nidoviruses encode both a ... Abnidovirineae Abyssoviridae Arnidovirineae Arteriviridae Cremegaviridae Gresnaviridae Olifoviridae Cornidovirineae ...
Simarterivirinae
The subfamily is in the family Arteriviridae and order Nidovirales. The subfamily contains six genera. Member viruses are ... Articles with 'species' microformats, Taxonbars without primary Wikidata taxon IDs, Nidovirales, Arteriviridae, Virus ...
Deltaarterivirus hemfev
It is a positive-stranded RNA virus classified in the family Arteriviridae. It is the only member of the subgenus Hedartevirus ... 8 August 2018). "Expansion of the rank structure of the family Arteriviridae and renaming its taxa" (docx). International ... Arteriviridae, Hemorrhagic fevers, All stub articles, Virus stubs). ...
Lactate dehydrogenase elevating virus
... constitutes the species Gamamaarterivirus lacdeh which is part of the family Arteriviridae and order Nidovirales. The order ...
Equine arteritis virus leader TRS hairpin (LTH)
Page for Equine arteritis virus leader TRS hairpin (LTH) at Rfam v t e (Cis-regulatory RNA elements, Arteriviridae, All stub ...
Arnidovirineae
Arteriviridae Cremegaviridae Gresnaviridae Olifoviridae Muarterivirus Alphaarterivirus Lambdaarterivirus Deltaarterivirus ... "Arteriviridae ~ ViralZone". viralzone.expasy.org. Retrieved 2022-07-26. Zhou, Zhijian; Qiu, Ye; Ge, Xingyi (2021-04-23). "The ...
Equine arterivirus serine peptidase
Arteriviridae, All stub articles, Enzyme stubs). ...
Zinc and the common cold
In the arteriviridae and coronaviridae families of virus that also cause the common cold, in vitro studies found that zinc ...
List of MeSH codes (B04)
... arteriviridae MeSH B04.820.504.080.100 - arterivirus MeSH B04.820.504.080.100.100 - arteritis virus, equine MeSH B04.820. ... arteriviridae MeSH B04.909.777.500.080.500 - arterivirus MeSH B04.909.777.500.080.500.100 - arteritis virus, equine MeSH ...
RNA virus
Order Nidovirales Family Arteriviridae Family Coronaviridae - includes Human coronavirus (common cold viruses HCoV-229E, HCoV- ...
List of virus families and subfamilies
Alphatetraviridae Alvernaviridae Amalgaviridae Amnoonviridae Ampullaviridae Anelloviridae Arenaviridae Arteriviridae ...
Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 - Volume 27, Number 2...
Arteriviruses (Arteriviridae). In: Granoff A, Webster R, editors. Encyclopedia of virology, 2nd ed. Amsterdam: Elsevier; 1999. ... We detected a novel pathogenic arterivirus in the ever expanding family Arteriviridae. Because no wild animals were identified ... Reorganization and expansion of the nidoviral family Arteriviridae. Arch Virol. 2016;161:755-68. DOIPubMedGoogle Scholar ... family Arteriviridae. Arteriviruses infect equids, pigs, possums, nonhuman primates, and rodents. For example, equine arteritis ...
An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small...
MeSH Browser
Arteriviridae Preferred Term Term UI T440530. Date03/23/2001. LexicalTag NON. ThesaurusID NLM (2002). ... Arteriviridae Preferred Concept UI. M0382051. Registry Number. txid76803. Scope Note. A family of viruses, of the order ... Arteriviridae. Tree Number(s). B04.820.578.500.080. Unique ID. D028382. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/ ...
TREE NUMBER DESCRIPTOR
DeCS
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MeSH Browser
Arteriviridae Preferred Term Term UI T440530. Date03/23/2001. LexicalTag NON. ThesaurusID NLM (2002). ... Arteriviridae Preferred Concept UI. M0382051. Registry Number. txid76803. Scope Note. A family of viruses, of the order ... Arteriviridae. Tree Number(s). B04.820.578.500.080. Unique ID. D028382. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/ ...
Orthohantavirus - Wikipedia
Findings of significant congruence between phylogenies of hantaviruses and phylogenies of their rodent reservoirs have led to the theory that rodents, although infected by the virus, are not harmed by it because of long-standing hantavirus-rodent host coevolution,[18][19] although findings in 2008 led to new hypotheses regarding hantavirus evolution.[20][21] Various hantaviruses have been found to infect multiple rodent species, and cases of cross-species transmission (host switching) have been recorded.[22][23][24] Additionally, rates of substitution based on nucleotide sequence data reveal that hantavirus clades and rodent subfamilies may not have diverged at the same time.[21][25] Furthermore, as of 2007 hantaviruses have been found in multiple species of non-rodent shrews and moles.[21][26][27][28] Taking into account the inconsistencies in the theory of coevolution, it was proposed in 2009 that the patterns seen in hantaviruses in relation to their reservoirs could be attributed to ...
Deakin University / All Locations
Pesquisa | Portal Regional da BVS
Arteriviridae/classificação , Arteriviridae/isolamento & purificação , Infecções por Vírus de RNA/veterinária , Arteriviridae/ ... Reorganization and expansion of the nidoviral family Arteriviridae. Kuhn, Jens H; Lauck, Michael; Bailey, Adam L; Shchetinin, ... The family Arteriviridae presently includes a single genus Arterivirus. This genus includes four species as the taxonomic homes ...
NEW (2002) MESH HEADINGS WITH SCOPE NOTES (UNIT RECORD FORMAT; 8/27/2001
CDC Science Clips
CDV Healthcare Answer Retrieval - PMC Open Access
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Nidovirales: a new order comprising Coronaviridae and Arteriviridae - PubMed
Science Clips - Volume 13, Issue 1, January 5, 2021
Code System Concept
Detection and Prevalence Patterns of Group I Coronaviruses in Bats, Northern Germany - Volume 14, Number 4-April 2008 -...
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CDC Science Clips
Pesquisa | Biblioteca Virtual em Saúde - BRASIL
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Nidovirales1
- The causal agent of EVA is a positive single-stranded RNA virus belonging to the Equarterivirinae genus of the Arteriviridae family in the Nidovirales order. (iswavld2023.org)
Family1
- LDV), equine arteritis virus, and simian hemorrhagic regenerated permissive macrophages and the escape from fever virus, belongs to the family Arteriviridae ( 6). (cdc.gov)