A family of viruses, of the order NIDOVIRALES, containing spherical virions. In contrast to CORONAVIRIDAE, no protruding spikes are obvious on the surface.
An order comprising three families of eukaryotic viruses possessing linear, nonsegmented, positive sense RNA genomes. The families are CORONAVIRIDAE; ARTERIVIRIDAE; and RONIVIRIDAE.
The type species of the genus ARTERIVIRUS and the etiologic agent of an important equine respiratory disease causing abortion, pneumonia, or other infections.
A genus of the family ARTERIVIRIDAE, in the order NIDOVIRALES. The type species is ARTERITIS VIRUS, EQUINE.
A species of ARTERIVIRUS causing reproductive and respiratory disease in pigs. The European strain is called Lelystad virus. Airborne transmission is common.
A contagious disease caused by canine adenovirus (ADENOVIRUSES, CANINE) infecting the LIVER, the EYE, the KIDNEY, and other organs in dogs, other canids, and bears. Symptoms include FEVER; EDEMA; VOMITING; and DIARRHEA.
Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
The systematic arrangement of entities in any field into categories classes based on common characteristics such as properties, morphology, subject matter, etc.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
Indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk.
A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).
A plant genus of the family Paeoniaceae, order Dilleniales, subclass Dilleniidae, class Magnoliopsida. These perennial herbs are up to 2 m (6') tall. Leaves are alternate and are divided into three lobes, each lobe being further divided into three smaller lobes. The large flowers are symmetrical, bisexual, have 5 sepals, 5 petals (sometimes 10), and many stamens.
An order comprising four families of eukaryotic viruses possessing linear, non-segmented, negative-strand RNA genomes. The families are BORNAVIRIDAE; FILOVIRIDAE; PARAMYXOVIRIDAE; and RHABDOVIRIDAE.
Infections with viruses of the order MONONEGAVIRALES. The concept includes FILOVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; and RHABDOVIRIDAE INFECTIONS.
A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster's New Geographical Dictionary, 1988, p715 & Room, Brewer's Dictionary of Names, 1992, p329)
A species in the genus Bornavirus, family BORNAVIRIDAE, causing a rare and usually fatal encephalitic disease in horses and other domestic animals and possibly deer. Its name derives from the city in Saxony where the condition was first described in 1894, but the disease occurs in Europe, N. Africa, and the Near East.
A republic stretching from the Indian Ocean east to New Guinea, comprising six main islands: Java, Sumatra, Bali, Kalimantan (the Indonesian portion of the island of Borneo), Sulawesi (formerly known as the Celebes) and Irian Jaya (the western part of New Guinea). Its capital is Djakarta. The ethnic groups living there are largely Chinese, Arab, Eurasian, Indian, and Pakistani; 85% of the peoples are of the Islamic faith.
An encephalomyelitis of horses, sheep and cattle caused by BORNA DISEASE VIRUS.
Infections caused by viruses of the genus ARTERIVIRUS.
A species of NAIROVIRUS of the family BUNYAVIRIDAE. It is primarily transmitted by ticks and causes a severe, often fatal disease in humans.
Proteins which are synthesized as a single polymer and then cleaved into several distinct proteins.
A group of viral diseases of diverse etiology but having many similar clinical characteristics; increased capillary permeability, leukopenia, and thrombocytopenia are common to all. Hemorrhagic fevers are characterized by sudden onset, fever, headache, generalized myalgia, backache, conjunctivitis, and severe prostration, followed by various hemorrhagic symptoms. Hemorrhagic fever with kidney involvement is HEMORRHAGIC FEVER WITH RENAL SYNDROME.
An enzyme that catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time, and can initiate a chain de novo. (Enzyme Nomenclature, 1992, p293)
Viruses whose genetic material is RNA.
A species of CORONAVIRUS causing atypical respiratory disease (SEVERE ACUTE RESPIRATORY SYNDROME) in humans. The organism is believed to have first emerged in Guangdong Province, China, in 2002. The natural host is the Chinese horseshoe bat, RHINOLOPHUS sinicus.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The number of mutations that occur in a specific sequence, GENE, or GENOME over a specified period of time such as years, CELL DIVISIONS, or generations.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
Ribonucleic acid that makes up the genetic material of viruses.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Spherical RNA viruses, in the order NIDOVIRALES, infecting a wide range of animals including humans. Transmission is by fecal-oral and respiratory routes. Mechanical transmission is also common. There are two genera: CORONAVIRUS and TOROVIRUS.
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.
Virus diseases caused by CORONAVIRIDAE.

Site-directed mutagenesis of the Nidovirus replicative endoribonuclease NendoU exerts pleiotropic effects on the arterivirus life cycle. (1/2)

The highly conserved NendoU replicative domain of nidoviruses (arteriviruses, coronaviruses, and roniviruses) belongs to a small protein family whose cellular branch is prototyped by XendoU, a Xenopus laevis endoribonuclease involved in nucleolar RNA processing. Recently, sequence-specific in vitro endoribonuclease activity was demonstrated for the NendoU-containing nonstructural protein (nsp) 15 of several coronaviruses. To investigate the biological role of this novel enzymatic activity, we have characterized a comprehensive set of arterivirus NendoU mutants. Deleting parts of the NendoU domain from nsp11 of equine arteritis virus was lethal. Site-directed mutagenesis of conserved residues exerted pleiotropic effects. In a first-cycle analysis, replacement of two conserved Asp residues in the C-terminal part of NendoU rendered viral RNA synthesis and virus production undetectable. In contrast, mutagenesis of other conserved residues, including two putative catalytic His residues that are absolutely conserved in NendoU and cellular homologs, produced viable mutants displaying reduced plaque sizes (20 to 80% reduction) and reduced yields of infectious progeny of up to 5 log units. A more detailed analysis of these mutants revealed a moderate reduction in RNA synthesis, with subgenomic RNA synthesis consistently being more strongly affected than genome replication. Our data suggest that the arterivirus nsp11 is a multifunctional protein with a key role in viral RNA synthesis and additional functions in the viral life cycle that are as yet poorly defined.  (+info)

Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between corona- and arteriviridae. (2/2)

The causative agent of severe acute respiratory syndrome (SARS) is the SARS-associated coronavirus, SARS-CoV. The nucleocapsid (N) protein plays an essential role in SARS-CoV genome packaging and virion assembly. We have previously shown that SARS-CoV N protein forms a dimer in solution through its C-terminal domain. In this study, the crystal structure of the dimerization domain, consisting of residues 270-370, is determined to 1.75A resolution. The structure shows a dimer with extensive interactions between the two subunits, suggesting that the dimeric form of the N protein is the functional unit in vivo. Although lacking significant sequence similarity, the dimerization domain of SARS-CoV N protein has a fold similar to that of the nucleocapsid protein of the porcine reproductive and respiratory syndrome virus. This finding provides structural evidence of the evolutionary link between Coronaviridae and Arteriviridae, suggesting that the N proteins of both viruses have a common origin.  (+info)

View Notes - Genetics from ANSC 1101 at LSU. Present ed by Matthew Garcia August 14, 2011 Decides which individuals become parents Choose most favorable individuals to become parents I mprove
One hallmark of the PRRS virus in swine is its extremely high genetic diversity. This phenomenon has important implications for disease diagnosis and prevention and is one of the major causes of the partial or complete lack of protection against re-infections.. The PRRS virus is an RNA virus that belongs to the genus Arterivirus, the only genus in the family Arteriviridae, in the order Nidovirales. The PRRS virus contains a non-segmented, single-stranded, positive-sense RNA genome. The RNA genome is composed of ten open reading frames (ORFs).. Since the first outbreaks of PRRS in swine in America and Europe, two PRRS virus genotypes have been designated: European or Type 1 (prototype Lelystad virus) and North-American or Type 2 (prototype VR-2332). Interestingly, similarity between both prototype nucleotide sequences is as low as 55%. More importantly, intratype pairwise nucleotide sequence variation exceeds 20% (up to 30% in type 1 and around 21% in type 2).. A significant number of subtypes ...
One hallmark of the PRRS virus in swine is its extremely high genetic diversity. This phenomenon has important implications for disease diagnosis and prevention and is one of the major causes of the partial or complete lack of protection against re-infections.. The PRRS virus is an RNA virus that belongs to the genus Arterivirus, the only genus in the family Arteriviridae, in the order Nidovirales. The PRRS virus contains a non-segmented, single-stranded, positive-sense RNA genome. The RNA genome is composed of ten open reading frames (ORFs).. Since the first outbreaks of PRRS in swine in America and Europe, two PRRS virus genotypes have been designated: European or Type 1 (prototype Lelystad virus) and North-American or Type 2 (prototype VR-2332). Interestingly, similarity between both prototype nucleotide sequences is as low as 55%. More importantly, intratype pairwise nucleotide sequence variation exceeds 20% (up to 30% in type 1 and around 21% in type 2).. A significant number of subtypes ...
Equine arteritis virus (EAV) and Porcine reproductive and respiratory syndrome virus (PRRSV) are enveloped RNA viruses belonging to the family Arteriviridae. EAV infection leads to abortion and respiratory illness in horses. PRRSV causes persistent infections in pigs, which is one of the main reasons for the economic losses in the swine industry. The glycoprotein complex Gp2/3/4 and Gp5/M are essential for cell entry and budding, respectively. PRRSV and EAV Gp2/3/4 ectodomains were co-expressed to determine their complex formation in insect cells. The results revealed that PRRSV Gp2/3/4 proteins secreted into the cell culture supernatant as a disulphide linked complex. In contrast, Gp3 of EAV was expressed, but not associated with Gp2/4. The Gp2/3/4 proteins of both PRRSV and EAV are attached to the membrane through their C-terminal hydrophobic transmembrane region as they were secreted when it is removed. This result showed that all the proteins contain type I membrane topology except EAV Gp3 since
This chapter focuses on the arterivirus proteins that are involved in genome replication and subgenomic RNA (sgRNA) synthesis. These proteins, which are collectively referred to as
Morgan, SB, Graham, SP, Salguero, J, Steinbach, F and Frossard, JP (2012) Increased pathology during infection with an atypical European porcine Arterivirus correlates with an enhanced adaptive immune response In: European Congress of Immunology, 2012-09-05 - 2012-09-08, Glasgow, SCOTLAND. Full text not available from this repository ...
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically important pathogens, that hinder the development of global pork industry. Its nonstructural protein 11 (nsp11), with the nidoviral uridylate-specific endoribonuclease (NendoU) domain, is essential for PRRSV genome replication and it also contributes to host innate immunity suppression. However, the immunogenicity and immune structure of PRRSV nsp11 have not been well investigated yet. In this study, a monoclonal antibody (mAb), designated 3F9, that against nsp11 was generated. Subsequently, a series of partially overlapped fragments, covered the nsp1140-223aa, were expressed to test the reactivity with mAb 3F9, and the 111DCREY115 was found to be the core unit of the B-cell epitope recognized by mAb 3F9. Further investigation indicated that both genotype 1 and genotype 2 PRRSV can be recognized by mAb 3F9, due to the 111DCREY115 is conserved in both genotype virus. Meanwhile, this epitope, localized at the
PRRSV is a member of the genus Arterivirus, family Arteriviridae, order Nidovirales. Other members of the genus Arterivirus ... 10 November 2015). "In the family Arteriviridae create 10 species (1 unassigned, 9 in the genus Arterivirus) and rename one ... Nidovirales Arteriviridae Porartevirus Porcine reproductive and respiratory syndrome virus 1 0 M96262.2 Nidovirales ... Nidovirales, Cavenagh D. (1997). "a new order comprising Coronaviridae and Arteriviridae". Arch Virol. 142 (3): 629-33. PMID ...
Familie Arteriviridae. *Unterfamilie Crocarterivirinae. *Genus Muarterivirus. *Unterfamilie Equarterivirinae. *Genus ...
PRRSV is in the Arteriviridae family and the order Nidovirales. It has a positive sense RNA genome that is 15 kb long. This ... As a member of the family Arteriviridae, PRRSV has an in vivo and in vitro tropism for cells like macrophages or monocytes. ...
The order includes the families Coronaviridae, Arteriviridae, Roniviridae, and Mesoniviridae. Member viruses have a viral ... a clade that includes the distantly related Arteriviridae (12.7-15.7 kb). The large nidoviruses encode both a 2'-O- ... Abnidovirineae Abyssoviridae Arnidovirineae Arteriviridae Cremegaviridae Gresnaviridae Olifoviridae Cornidovirineae ...
Mononegavirales adalah ordo virus RNA yang berada dalam filum Negarnaviricota dan kelas Monjiviricetes.[1] Nama Mononegavirales berasa dari bahasa Yunani μóνος [monos] yang merujuk pada genom untai tunggal pada sebagian besar ordo ini, bahasa Latin negare yang merujuk pada sifat sense-negatif genom virus, serta akhiran -virales yang menunjukkan ordo virus.[2] Anggota ordo ini yang dikenal di antaranya virus rabies dan virus Ebola yang dapat menyebabkan penyakit, baik pada manusia maupun hewan. ...
The arteriviridae infect macrophages in animals and cause a variety of diseases. LDV specifically causes lifelong persistent ... Lactate dehydrogenase elevating virus, or LDV for short, belongs to part of the arteriviridae family and the nidovirales order ...
It is a positive-stranded RNA virus classified in the family Arteriviridae. It is the only member of the subgenus Hedartevirus ... 8 August 2018). "Expansion of the rank structure of the family Arteriviridae and renaming its taxa" (docx). International ...
Arteriviridae Arterivirus, equine arteritis virus Enveloped Icosahedral ss IV 16. Hepeviridae Hepatitis E virus Naked ...
In the arteriviridae and coronaviridae families of virus that also cause the common cold, in vitro studies found that zinc ...
... arteriviridae MeSH B04.820.504.080.100 - arterivirus MeSH B04.820.504.080.100.100 - arteritis virus, equine MeSH B04.820. ... arteriviridae MeSH B04.909.777.500.080.500 - arterivirus MeSH B04.909.777.500.080.500.100 - arteritis virus, equine MeSH ...
Order Nidovirales Family Arteriviridae Family Coronaviridae - includes Human coronavirus (common cold viruses HCoV-229E, HCoV- ...
Alphatetraviridae Alvernaviridae Amalgaviridae Amnoonviridae Ampullaviridae Anelloviridae Arenaviridae Arteriviridae ...
... is a family of viruses in the suborder Arnidovirineae. Members of the family are known as arteriviruses. Positive ... Family: Arteriviridae; subfamilies: Crocarterivirinae Equarterivirinae Heroarterivirinae Simarterivirinae Variarterivirinae ...
Arteriviridae , Arterivirus: , Ascoviridae , Ascovirus: , Asfarviridae , Asfivirus: , Astroviridae , Atadenovirus: , ...
When retroviruses have integrated their own genome into the germ line, their genome is passed on to a following generation. These endogenous retroviruses (ERVs), contrasted with exogenous ones, now make up 5-8% of the human genome.[7] Most insertions have no known function and are often referred to as "junk DNA". However, many endogenous retroviruses play important roles in host biology, such as control of gene transcription, cell fusion during placental development in the course of the germination of an embryo, and resistance to exogenous retroviral infection. Endogenous retroviruses have also received special attention in the research of immunology-related pathologies, such as autoimmune diseases like multiple sclerosis, although endogenous retroviruses have not yet been proven to play any causal role in this class of disease.[8] While transcription was classically thought to occur only from DNA to RNA, reverse transcriptase transcribes RNA into DNA. The term "retro" in retrovirus refers to ...
The hepatitis envelope proteins are composed of subunits made from the viral preS1, preS2, and S genes. The L (for "large") envelope protein contains all three subunits. The M (for "medium") protein contains only preS2 and S. The S (for "small") protein contains only S. The genome portions encoding these envelope protein subuntis share both the same frame and the same stop codon (generating nested transcripts on a single open reading frame. The pre-S1 is encoded first (closest to the 5' end), followed directly by the pre-S2 and the S. When a transcript is made from the beginning of the pre-S1 region, all three genes are included in the transcript and the L protein is produced. When the transcript starts after the pro-S1 at the beginning of the pre-S2 the final protein contains the pre-S2 and S subunits only and therefore is an M protein. The smallest envelope protein containing just the S subunit is made most because it is encoded closest to the 3' end and comes from the shortest transcript. ...
Viruses in Betanodavirus are non-enveloped, with icosahedral geometries, and T=3 symmetry. The diameter is around 30 nm. Genomes are linear and segmented, bipartite, around 21.4kb in length.[8]. The crystal structure of a betanodavirus- T=3 Grouper nervous necrosis virus (GNNV)-like particle has been determined by X-ray crystallography. The virus-like particle contains 180 subunits of the capsid protein, and each capsid protein (CP) shows three major domains: (i) the N-terminal arm, an inter-subunit extension at the inner surface; (ii) the shell domain (S-domain), a jelly-roll structure; and (iii) the protrusion domain (P-domain) formed by three-fold trimeric protrusions. [10]. ...
Nucleic acid analysis suggests a very long association of the viruses with the wasps (greater than 70 million years).. Two proposals have been advanced for how the wasp/virus association developed. The first suggests that the virus is derived from wasp genes. Many parasitoids that do not use PDVs inject proteins that provide many of the same functions, that is, a suppression of the immune response to the parasite egg. In this model, the braconid and ichneumonid wasps packaged genes for these functions into the viruses-essentially creating a gene-transfer system that results in the caterpillar producing the immune-suppressing factors. In this scenario, the PDV structural proteins (capsids) were probably "borrowed" from existing viruses.. The alternative proposal suggests that ancestral wasps developed a beneficial association with an existing virus that eventually led to the integration of the virus into the wasp's genome. Following integration, the genes responsible for virus replication and the ...
Louis Pasteur was unable to find a causative agent for rabies and speculated about a pathogen too small to be detected using a microscope.[21] In 1884, the French microbiologist Charles Chamberland invented a filter (known today as the Chamberland filter or the Pasteur-Chamberland filter) with pores smaller than bacteria. Thus, he could pass a solution containing bacteria through the filter and completely remove them from the solution.[22] In 1892, the Russian biologist Dmitri Ivanovsky used this filter to study what is now known as the tobacco mosaic virus. His experiments showed that crushed leaf extracts from infected tobacco plants remain infectious after filtration. Ivanovsky suggested the infection might be caused by a toxin produced by bacteria, but did not pursue the idea.[23] At the time it was thought that all infectious agents could be retained by filters and grown on a nutrient medium - this was part of the germ theory of disease.[2] In 1898, the Dutch microbiologist Martinus ...
The Herpesvirales naming system originated in 1973 and has been elaborated considerably since. All herpesviruses described since this system was adopted have been named in accordance with it. The recommended naming system specifies that each species name consists of three parts: a first word, a second word, and finally a number. The first word should be derived from the taxon (family or subfamily) to which its primary natural host belongs. The subfamily name is used for viruses from members of the family Bovidae or from primates (the virus name ending in -ine, e.g. bovine), and the host family name for other viruses (ending in -id, e.g. equid). Human herpesviruses have been treated as an exception (human rather than hominid). Following the host-derived term, species in the family Herpesviridae, which are divided into subfamilies Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae, will have the word alphaherpesvirus, betaherpesvirus, or gammaherpesvirus added, respectively. Species in ...
Despite his other successes, Louis Pasteur (1822-1895) was unable to find a causative agent for rabies and speculated about a pathogen too small to be detected using a microscope.[1] In 1884, the French microbiologist Charles Chamberland (1851-1931) invented a filter - known today as the Chamberland filter - that had pores smaller than bacteria. Thus, he could pass a solution containing bacteria through the filter and completely remove them from the solution.[2] In 1876, Adolf Mayer, who directed the Agricultural Experimental Station in Wageningen was the first to show that what he called "Tobacco Mosaic Disease" was infectious, he thought that it was caused by either a toxin or a very small bacterium. Later, in 1892, the Russian biologist Dmitry Ivanovsky (1864-1920) used a Chamberland filter to study what is now known as the tobacco mosaic virus. His experiments showed that crushed leaf extracts from infected tobacco plants remain infectious after filtration. Ivanovsky suggested the infection ...
Gammaherpesviruses are of primary interest due to the two human viruses, EBV and KSHV and the diseases they cause. The gammaherpesviruses replicate and persist in lymphoid cells but some are capable of undergoing lytic replication in epithelial or fibroblast cells. Gammaherpesviruses may be a cause of chronic fibrotic lung diseases in humans and in animals.[10] Murid herpesvirus 68 is an important model system for the study of gammaherpesviruses with tractable genetics. The gammaherpesviruses, including HVS, EBV, KSHV, and RRV, are capable of establishing latent infection in lymphocytes.[9] Attenuated virus mutants represent a promising approach towards gamma-herpesvirus infection control. Surprisingly, latency-deficient and, therefore, apathogenic MHV-68 mutants are found to be highly effective vaccines against these viruses.[8] Research in this area is almost exclusively performed using MHV68 as KSHV and EBV (the major human pathogens of this family) do not productively infect model organisms ...
The Birnaviridae genome encodes several proteins: Birnaviridae RNA-directed RNA polymerase (VP1), which lacks the highly conserved Gly-Asp-Asp (GDD) sequence, a component of the proposed catalytic site of this enzyme family that exists in the conserved motif VI of the palm domain of other RNA-directed RNA polymerases.[3] The large RNA segment, segment A, of birnaviruses codes for a polyprotein (N-VP2-VP4-VP3-C) [4] that is processed into the major structural proteins of the virion: VP2, VP3 (a minor structural component of the virus), and into the putative protease VP4.[4] VP4 protein is involved in generating VP2 and VP3.[4] recombinant VP3 is more immunogenic than recombinant VP2.[5] Infectious pancreatic necrosis virus (IPNV), a birnavirus, is an important pathogen in fish farms. Analyses of viral proteins showed that VP2 is the major structural and immunogenic polypeptide of the virus.[6][7] All neutralizing monoclonal antibodies are specific to VP2 and bind to continuous or discontinuous ...
Arteriviridae · Coronaviridae · Roniviridae. Astroviridae · Barnaviridae · Bromoviridae · Caliciviridae · Closteroviridae · ...
Arteriviridae is a family of viruses in the suborder Arnidovirineae. Members of the family are known as arteriviruses. Positive ... Family: Arteriviridae; subfamilies: Crocarterivirinae Equarterivirinae Heroarterivirinae Simarterivirinae Variarterivirinae ...
Arteriviridae (50 - 70 nm in diameter). Positive sense, single-stranded RNA viruses that have a spherical appearance due to the ... Available at: https://www.ivis.org/library/concise-review-of-veterinary-virology/arteriviridae-0 (Accessed: 13 August 2020). ...
Familia: Arteriviridae. Genera: Dipartevirus - Equartevirus - Nesartevirus - Porartevirus - Simartevirus Name[edit]. ... Arteriviridae References[edit]. *Snijder, E.J. & Meulenberg, J.J.M. 2001: Arteriviruses. In: Fields Virology, 4th ed., (D.M. ... Retrieved from "https://species.wikimedia.org/w/index.php?title=Arteriviridae&oldid=5500984" ...
Domain architectures: Arteriviridae zinc-binding domain (IPR027355). Showing 1 to 20 of 25 results ...
The continuous growth of knowledege makes it very difficult for scientists to retrieve comprehensive and accurate data on viruses. The desired information is often dispersed in a variety of books, jou
Arteriviridae. In: Concise Review of Veterinary Virology Author(s):. Carter G.R. and ...
Familie Arteriviridae. *Unterfamilie Crocarterivirinae. *Genus Muarterivirus. *Unterfamilie Equarterivirinae. *Genus ...
Arteriviridae 26. Picornaviridae 27. Caliciviridae 28. Astroviridae 29. Togaviridae 30. Flaviviridae 31. Other Viruses: ...
Family Arteriviridae Family Papillomaviridae Family Parvoviridae TT Virus: A Newly Described Human Virus Further Reading The ...
Arteriviridae: 03.004.0.01. Arterivirus: 03.004.0.01.002. Simian hemorrhagic fever virus. In: A.J. Davison, et al. (chair), ... Arteriviridae: 03.004.0.01. Arterivirus: 03.004.0.01.003. Lactate dehydrogenase elevating virus. In: A.J. Davison, et al. ( ...
Family Arteriviridae 384. Family Bornaviridae 386. Family Flaviviridae 386. Family Bunyaviridae 391 ...
Arteriviridae. Genus. Arterivirus. Family. Coronaviridae. Subfamily. Coronavirinae. Genus. Alphacoronavirus. Genus. ...
Arteriviruses (Arteriviridae). In: Granoff A, Webster R, editors. Encyclopedia of virology, 2nd ed. Amsterdam: Elsevier; 1999. ... We detected a novel pathogenic arterivirus in the ever expanding family Arteriviridae. Because no wild animals were identified ... Reorganization and expansion of the nidoviral family Arteriviridae. Arch Virol. 2016;161:755-68. DOIPubMed ... family Arteriviridae. Arteriviruses infect equids, pigs, possums, nonhuman primates, and rodents. For example, equine arteritis ...
Mononegavirales adalah ordo virus RNA yang berada dalam filum Negarnaviricota dan kelas Monjiviricetes.[1] Nama Mononegavirales berasa dari bahasa Yunani μóνος [monos] yang merujuk pada genom untai tunggal pada sebagian besar ordo ini, bahasa Latin negare yang merujuk pada sifat sense-negatif genom virus, serta akhiran -virales yang menunjukkan ordo virus.[2] Anggota ordo ini yang dikenal di antaranya virus rabies dan virus Ebola yang dapat menyebabkan penyakit, baik pada manusia maupun hewan. ...
The families are CORONAVIRIDAE; ARTERIVIRIDAE; and RONIVIRIDAE.. Mandible. The largest and strongest bone of the FACE ...
Reorganization and expansion of the nidoviral family Arteriviridae.. Kuhn JH, Lauck M, Bailey AL, Shchetinin AM, Vishnevskaya ... Genome Sequences of Simian Hemorrhagic Fever Virus Variant NIH LVR42-0/M6941 Isolates (Arteriviridae: Arterivirus). ...
Reorganization and expansion of the nidoviral family Arteriviridae.. Kuhn JH, Lauck M, Bailey AL, Shchetinin AM, Vishnevskaya ...
Arteriviridae Arterivirus, equine arteritis virus Enveloped Icosahedral ss IV 16. Hepeviridae Hepatitis E virus Naked ...
PRRSV is a member of the genus Arterivirus, family Arteriviridae, order Nidovirales. Other members of the genus Arterivirus ... 10 November 2015). "In the family Arteriviridae create 10 species (1 unassigned, 9 in the genus Arterivirus) and rename one ... Nidovirales Arteriviridae Porartevirus Porcine reproductive and respiratory syndrome virus 1 0 M96262.2 Nidovirales ... Nidovirales, Cavenagh D. (1997). "a new order comprising Coronaviridae and Arteriviridae". Arch Virol. 142 (3): 629-33. PMID ...
Belongs to the arteriviridae polyprotein family.Curated. Zinc finger. Feature key. Position(s). DescriptionActions. Graphical ... Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Nidovirales › Arteriviridae › Simartevirus ...
The order Nidovirales contains three families: Coronviridae, Roniviridae, and Arteriviridae. Roniviruses seem to infect shrimp ...
Nidovirales I (Arteriviridae). 26 April 2021. Nidovirales II (Coronaviridae). Bunyavirales, Arenaviridae. 3 May 2021. ...
Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 142:629-633. ...
2016). Reorganization and expansion of the nidoviral family arteriviridae. Arch. Virol. 161, 755-768. doi: 10.1007/s00705-015- ...
Family Arteriviridae. *Family Coronaviridae - includes Coronavirus, SARS. *Family Roniviridae. *Unassigned *Family Astroviridae ...
The PRRSV belongs to the order Nidovirales, family Arteriviridae, genus Arterivirus [1]. The PRRSV genome contains at least 9 ...
Cavanagh D (1997) Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch Virol 142:629-633PubMedGoogle ...
Nidoviruses (Coronaviridae, Arteriviridae, and Roniviridae) feature the most complex genetic organization among plus-strand RNA ...
Porcine reproductive and respiratory syndrome virus (PRRSV) is a member of family Arteriviridae which, along with the ... Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 142:629-633. ... the prototypic family member of Arteriviridae (41). Each of these NSP constructs was cotransfected into HeLa cells, along with ... the prototypic member of Arteriviridae family, antagonizes host innate immune response by deconjugating ubiquitin and ISG15 ...
  • Cavanagh D (1997) Nidovirales: a new order comprising Coronaviridae and Arteriviridae. (springer.com)
  • Nidoviruses (Coronaviridae, Arteriviridae, and Roniviridae) feature the most complex genetic organization among plus-strand RNA viruses. (ebi.ac.uk)
  • Porcine reproductive and respiratory syndrome virus (PRRSV) is a member of family Arteriviridae which, along with the Coronaviridae , are classified in the order Nidovirales ( 9 ). (asm.org)
  • On the basis of conserved amino acid sequence motifs in their polymerase (poly)proteins and similarities in their genome organization and gene expression strategy, the Arteriviridae have been grouped together with the Coronaviridae and the recently established family Roniviridae in the order Nidovirales ( 2 , 3 , 4 ). (asm.org)
  • Nidoviruses (Coronaviridae, Arteriviridae, and Roniviridae) feature the most complex genetic organization among plus-strand RNA viruses [ E1 , E2 , E3 ]. (expasy.org)
  • Cavanagh Deborah: Nidovirales: a whole new get containing Coronaviridae and also Arteriviridae. (carbonminds.com)
  • Both PRRSV1 and PRRSV2 belong to the genus Porarterivirus , one of the five genera established within the family Arteriviridae , placed with the families Mesoniviridae , Roniviridae and Coronaviridae in the order Nidovirales. (hipra.com)
  • Arteriviruses are enveloped, spherical viruses with a positive-sense, single-stranded, linear RNA genome ( 1 ), and they are assigned to the order Nidovirales, family Arteriviridae . (cdc.gov)
  • PRRSV is a member of the genus Arterivirus, family Arteriviridae, order Nidovirales. (wikipedia.org)
  • The PRRSV belongs to the order Nidovirales, family Arteriviridae, genus Arterivirus [ 1 ]. (hindawi.com)
  • Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus belonging to the family Arteriviridae of the order Nidovirales . (asm.org)
  • The causative agent is a positive sense RNA virus that groups within the order Nidovirales , family Arteriviridae , and is referred to as the PRRS virus (PRRSV) [3] . (prolekare.cz)
  • It is the prototype virus of the family Arteriviridae (genus Arterivirus, order Nidovirales) [4, 5]. (ukessays.com)
  • In 1996, the family Arteriviridae was included within the order Nidovirales. (caister.com)
  • The PRRS virus (PRRSV) is an enveloped positive-stranded RNA virus which belongs to the family of Arteriviridae in the order of the Nidovirales . (beds.ac.uk)
  • The PRRS virus is an enveloped RNA virus in the genus Arterivirus, classified in the virus family, Arteriviridae. (iastate.edu)
  • Equine viral arteritis (EVA) is a highly contagious disease of equines and is caused by equine arteritis virus (EAV), a RNA virus belonging to the genus Arterivirus in the family Arteriviridae. (expertsmind.com)
  • Porcine reproductive and respiratory syndrome virus (PRRSV), a member of the genus Arterivirus in the family Arteriviridae, is the most important viral pathogens in swine industry worldwide. (bvsalud.org)
  • Genus Tequatrovirus ( T4virus , T4-ähnliche Viren , en. (wikipedia.org)
  • Other members of this single genus in the family Arteriviridae are Lactate dehydrogenase-elevating virus (LDV), Porcine reproductive and respiratory syndrome virus (PRRSV), and Simian hemorrhagic fever virus . (asm.org)
  • The etiological agent, PRRSV belongs to the genus Artevirus within the family Arteriviridae, and its strains are divided into major genotypes. (hipra.com)
  • Equine arteritis virus (EAV) and Porcine reproductive and respiratory syndrome virus (PRRSV) are enveloped RNA viruses belonging to the family Arteriviridae. (dissertation.com)
  • The causal agent is an RNA-virus (PRRSV) from the Arteriviridae family that is highly mutagenic and resistant to the low temperatures registered in Midwestern areas of the US, where a significant proportion of the US swine industry is located. (swineweb.com)
  • Porcine reproductive and respiratory syndrome virus (PRRSV) is a small enveloped, positive-stranded RNA virus belonging to the family Arteriviridae. (bvsalud.org)
  • PRRSV is a positive-sense ssRNA enveloped virus of the family Arteriviridae. (cvd.com.ua)
  • LDV), equine arteritis virus, and simian hemorrhagic regenerated permissive macrophages and the escape from fever virus, belongs to the family Arteriviridae ( 6). (cdc.gov)
  • El genoma del virus del PRRS consiste en una sola cadena no segmentada de ARN de sentido positivo. (prrscontrol.com)
  • Arteriviridae (50 - 70 nm in diameter). (ivis.org)
  • It is an enveloped, positive-stranded RNA virus, belonging to the family Arteriviridae . (biomedcentral.com)