Takayasu Arteritis: A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.Arteritis: INFLAMMATION of any ARTERIES.Giant Cell Arteritis: A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)Arteritis Virus, Equine: The type species of the genus ARTERIVIRUS and the etiologic agent of an important equine respiratory disease causing abortion, pneumonia, or other infections.Temporal Arteries: Arteries arising from the external carotid or the maxillary artery and distributing to the temporal region.Polymyalgia Rheumatica: A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.Arterivirus Infections: Infections caused by viruses of the genus ARTERIVIRUS.Polyarteritis Nodosa: A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.HLA-B52 Antigen: A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*52 allele family.Aortic Arch Syndromes: Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.Horse Diseases: Diseases of domestic and wild horses of the species Equus caballus.Blood Sedimentation: Measurement of rate of settling of erythrocytes in anticoagulated blood.Aortitis: Inflammation of the wall of the AORTA.Arterivirus: A genus of the family ARTERIVIRIDAE, in the order NIDOVIRALES. The type species is ARTERITIS VIRUS, EQUINE.Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.Subclavian Artery: Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.Horses: Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.Subclavian Steal Syndrome: A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)Axillary Artery: The continuation of the subclavian artery; it distributes over the upper limb, axilla, chest and shoulder.Biopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Optic Neuropathy, Ischemic: Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)Angiography: Radiography of blood vessels after injection of a contrast medium.Mucocutaneous Lymph Node Syndrome: An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.Strongyle Infections, Equine: Infection of horses with parasitic nematodes of the superfamily STRONGYLOIDEA. Characteristics include the development of hemorrhagic nodules on the abdominal peritoneum.Brachiocephalic Trunk: The first and largest artery branching from the aortic arch. It distributes blood to the right side of the head and neck and to the right arm.Vasculitis: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.Vasculitis, Central Nervous System: Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)Adrenal Cortex HormonesMagnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Aortography: Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.Anti-Inflammatory Agents: Substances that reduce or suppress INFLAMMATION.Lactobacillus casei: A rod-shaped bacterium isolated from milk and cheese, dairy products and dairy environments, sour dough, cow dung, silage, and human mouth, human intestinal contents and stools, and the human vagina.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Aneurysm: Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.Arachnoiditis: Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)AIDS Arteritis, Central Nervous System: Inflammation of ARTERIES in the CENTRAL NERVOUS SYSTEM that occurs in patients with ACQUIRED IMMUNODEFICIENCY SYNDROME or AIDS-RELATED OPPORTUNISTIC INFECTIONS.Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.Methylprednisolone: A PREDNISOLONE derivative with similar anti-inflammatory action.Infarction: Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.Retinal Artery Occlusion: Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye.Blindness: The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.Adie Syndrome: A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)Renal Artery: A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.Togaviridae: A family of RNA viruses, mainly arboviruses, consisting of two genera: ALPHAVIRUS (group A arboviruses), and RUBIVIRUS. Virions are spherical, 60-70 nm in diameter, with a lipoprotein envelope tightly applied to the icosahedral nucleocapsid.Aorta, Abdominal: The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.Vasa Vasorum: Nutrient blood vessels which supply the walls of large arteries or veins.Ultrasonography, Doppler, Color: Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Amaurosis Fugax: Transient complete or partial monocular blindness due to retinal ischemia. This may be caused by emboli from the CAROTID ARTERY (usually in association with CAROTID STENOSIS) and other locations that enter the central RETINAL ARTERY. (From Adams et al., Principles of Neurology, 6th ed, p245)Vertebral Artery: The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).Vaccines, Marker: Vaccines used in conjunction with diagnostic tests to differentiate vaccinated animals from carrier animals. Marker vaccines can be either a subunit or a gene-deleted vaccine.Aorta: The main trunk of the systemic arteries.Aorta, Thoracic: The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Arteries: The vessels carrying blood away from the heart.Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).
Aleutian disease
Fibrin ring granuloma
Florencio (horse)
Duffy antigen system
Ostial disease
Temporomandibular joint
Jonathan Hutchinson
Giant Cell Arteritis - Symptoms, Treatments and Resources for Giant Cell Arteritis
Polymyalgia rheumatica and giant cell arteritis | GPonline
9780198729204: Polymyalgia Rheumatica and Giant Cell Arteritis (Oxford Rheumatology Library) - AbeBooks: 0198729200
Blood dehydroepiandrosterone sulphate (DHEAS) levels in polymyalgia rheumatica/giant cell arteritis & primary fibromyalgia (FM)
Tissue cytokine patterns in patients with polymyalgia rheumatica and giant cell arteritis
Diffuse Eosinophilic Arteritis | The BMJ
Temporal Arteritis | Giant Cell Arteritis | MedlinePlus
What are the racial predilections of Takayasu arteritis?
Temporal Arteritis Pathology: Definition, Epidemiology, Etiology
Obliterative Brachiocephalic Arteritis | Circulation
Takayasu Arteritis Imaging: Practice Essentials, Radiography, Ultrasonography
Giant Cell Arteritis | HealthLink BC
Formed visual hallucinations: a symptom of cranial arteritis. | The BMJ
Takayasu's arteritis - definition of Takayasu's arteritis by The Free Dictionary
Typical angina in a patient with Takayasu arteritis. - PubMed - NCBI
Three Presentations of Takayasu's Arteritis in Hispanic Patients
Takayasus's Arteritis in Northeast Iran - 613 Words | Bartleby
Takayasu's arteritis symptoms, treatments & forums | PatientsLikeMe
A Rare Cause of Pericardial Effusion: Giant Cell Arteritis
List of Temporal Arteritis Medications (3 Compared) - Drugs.com
TakayasuPolymyalgia rheumatica and giant cell arteGiant cell arteritis and polymyalgia rheumSymptoms of giant cell arteClinicalGlucocorticoidEquineArteryRheumatologyOccurVasculitisTakayasu ArteritisTakayasu's ArteritisCranialArteriesPolymyalgia Rheumatica and Giant Cell ArteIncidenceKnown as temporal arteritisInflammatoryEstablishing the diagnosis of temporal arteritisChronicCriteria for diagnosing gianPatients with suspected giant cell arte2016Giant Cell Arteritis SymSimilar to giant cell arteBiopsy-proven giant cell arteSuffer from temporal arteritisSymptoms of temporal arteritisDevelopment of giant cell arteAffectsTreatmentEquine arteritis virusHeadacheCorticosteroidSevereVascularOccurs
Takayasu3
- Prepulseless Phase Takayasu arteritis, also referred to as pulseless disease and aortic arch syndrome, is a rare chronic inflammatory vasculitis that primarily affects large- and medium-sized vessels. (visualdx.com)
- No definitive cause of Takayasu arteritis has been identified, but it is thought to be an IgG-mediated autoimmune vasculitis, perhaps triggered by a cross-reacting infectious agent. (visualdx.com)
- Takayasu arteritis in children rarely presents with pulselessness, claudication, or bruits. (visualdx.com)
Polymyalgia rheumatica and giant cell arte1
- Diagnosis and management of polymyalgia rheumatica and giant cell arteritis, including American College of Rheumatology criteria for a diagnosis, recommended corticosteroid therapy and potential side-effects of treatment. (gponline.com)
Giant cell arteritis and polymyalgia rheum1
- An international expert in giant cell arteritis and polymyalgia rheumatica, Professor Dasgupta is well known for his ground-breaking work on establishing criteria for diagnosing giant cell arteritis (GCA). (abebooks.com)
Symptoms of giant cell arte1
- If you have symptoms of giant cell arteritis (GCA) and your doctor believes you may have it, he or she may order a temporal artery biopsy to make sure. (peacehealth.org)
Clinical2
- It has been suggested that polymyalgia rheumatica (PMR) and temporal arteritis are clinical syndromes that form part of the spectrum of giant cell arteritis (GCA), so are different manifestations of the same disease process. (gponline.com)
- Giant cell arteritis, an inflammatory form of vasculitis, may present with a broad spectrum of clinical manifestations and can be complicated by acute ischemic events, the most serious of which is permanent blindness. (abebooks.com)
Glucocorticoid1
- Objective: To determine patient experiences of glucocorticoid (GC) therapy in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). (sahmriresearch.org)
Equine2
- A one-tube real-time TaqMan® reverse transcription-polymerase chain reaction (RT-PCR) assay was developed for the detection of equine arteritis virus (EAV). (elsevier.com)
- cDNA copies of the M and N genes of equine arteritis virus (EAV) isolates were synthesized by reverse transcription followed by polymerase chain reaction amplification. (microbiologyresearch.org)
Artery4
- We would like to report 2 cases of suspected temporal arteritis which were managed without routine temporal artery biopsy. (asianjo.com)
- If a temporal artery biopsy shows no signs of inflammation but your symptoms strongly suggest giant cell arteritis, you and your doctor will discuss the risks and benefits of treatment and of no treatment. (peacehealth.org)
- Temporal artery biopsy is the gold standard investigation for the diagnosis of giant cell arteritis. (rcpe.ac.uk)
- The aim of this retrospective study was to investigate the use of temporal artery biopsy in diagnosing giant cell arteritis in south-east Scotland over a five-year period. (rcpe.ac.uk)
Rheumatology2
- Although there are no widely accepted standard treatment protocols in relation to dose or duration of treatment, guidelines from the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) recommend starting corticosteroid therapy with 12.5-25mg/day of prednisolone or the equivalent (see resources), or 40-60mg daily for GCA where temporal arteritis is suspected. (gponline.com)
- Part of the Oxford Rheumatology Library series, P olymyalgia Rheumatica and Giant Cell Arteritis provides quick and practically relevant information on several aspects of the diseases, particularly on diagnosis and management, with the ultimate aim of improving the patient's care. (abebooks.com)
Occur1
- Although GCA, including temporal arteritis, is linked with PMR, both conditions can occur in isolation. (gponline.com)
Vasculitis33
- Arteritis and phlebitis are forms of vasculitis. (wikipedia.org)
- Takayasu's arteritis (also known as Takayasu's disease, "aortic arch syndrome," "nonspecific aortoarteritis," and "pulseless disease") is a form of large vessel granulomatous vasculitis with massive intimal fibrosis and vascular narrowing, most commonly affecting often young or middle-age women of Asian descent, though anyone can be affected. (wikipedia.org)
- Takayasu's arteritis is similar to other forms of vasculitis, including giant cell arteritis which typically affects older individuals. (wikipedia.org)
- Giant cell arteritis is a systemic obliterative vasculitis mainly involving the arteries that originate from the arch of the aorta. (medscape.com)
- Giant cell arteritis, also called temporal arteritis or cranial arteritis , is a serious disease characterized by inflammation of the walls of the blood vessels ( vasculitis ). (medicinenet.com)
- Temporal arteritis , also known as giant-cell arteritis and cranial arteritis, is a systemic vasculitis of medium-sized and large-sized arteries. (medscape.com)
- [ 3 ] Temporal arteritis is the most common systemic vasculitis of adults in Western countries. (medscape.com)
- Takayasu's arteritis is a form of vasculitis - inflammation of the blood vessels - that damages the large arteries, especially the aorta. (mayoclinic.org)
- Takayasu's arteritis (tah-kah-YAH-sooz ahr-tuh-RIE-tis) is a rare type of vasculitis, a group of disorders that cause blood vessel inflammation. (mayoclinic.org)
- Takayasu arteritis is a granulomatous vasculitis of unknown etiology that commonly affects the thoracic aorta and its branches, the pulmonary arteries, and the coronary arteries. (medscape.com)
- Table 1 Differential diagnosis of digital ischaemia post-cardiac surgery Aetiology Pathology and clinical examples Vessel wall Atherosclerosis Vasculitis: drug induced, cryoglobulinaemia, Takayasu's arteritis , Wegener's granulomatosis, Reynaud's syndrome, systemic sclerosis, mixed connective tissue disease Embolism Cardiac source Proximal arterial aneurysm Thrombosis Atherosclerosis Arterial reconstruction Arterial catheter injury Arterial dissection Antiphospholipid syndrome Thrombosic thrombocytopenia purpura HITTS Disseminated intravascular coagulation Trauma/physical Drugs, e. (thefreedictionary.com)
- Takayasu arteritis (TA) is a well-reported form of large-vessel vasculitis that primarily affects the aorta and its major branches. (nih.gov)
- Takayasu's arteritis (TA) is a medium and large vessel vasculitis, defined as a nonspecific aortitis that usually involves the aorta and its branches Kobayashi and Numano (2002). (hindawi.com)
- Introduction: Takayasu's arteritis (TA) is a chronic vasculitis of unknown etiology. (bartleby.com)
- Giant cell arteritis (GCA) is the most common systemic vasculitis in persons aged 50 and above (incidence, 3.5 per 100 000 per year). (aerzteblatt.de)
- Takayasu arteritis (TA) is a chronic large-vessel vasculitis that mainly affects the aorta and its major branches. (clinicaltrials.gov)
- Takayasu arteritis (TA) is a chronic vasculitis that causes inflammation of the aorta and its main branches and is characterized by adventitial thickening and cellular infiltration of the tunica media, with local destruction of vascular smooth muscle cells and elastin. (clinicaltrials.gov)
- (cmaj.ca)
- Giant cell arteritis (GCA), temporal arteritis or Horton's arteritis, is a systemic vasculitis which involves large and medium sized vessels, especially the extracranial branches of the carotid arteries, in persons usually older than 50 years. (bmj.com)
- Giant cell arteritis (GCA), temporal arteritis or Horton's arteritis, is a relatively common systemic vasculitis. (bmj.com)
- Takayasu arteritis is a chronic vasculitis with an unknown cause which frequently involves the aorta and its main branches. (thefreedictionary.com)
- Temporal arteritis is a type of vasculitis . (thefreedictionary.com)
- Giant cell arteritis, an inflammatory form of vasculitis, may present with a broad spectrum of clinical manifestations and can be complicated by acute ischemic events, the most serious of which is permanent blindness. (abebooks.com)
- Takayasu arteritis(TA) is a chronic progressive vasculitis predominantly affecting the aorta and its major branches. (bioportfolio.com)
- Takayasu's arteritis (TA) is a large vessel vasculitis. (clinicaladvisor.com)
- Lastly, Takayasu's arteritis needs to be differentiated from giant cell arteritis, the other large vessel vasculitis. (clinicaladvisor.com)
- Giant cell arteritis is a granulomatous immune-mediated vasculitis of medium and large vessels. (ovid.com)
- Prepulseless Phase Takayasu arteritis, also referred to as pulseless disease and aortic arch syndrome, is a rare chronic inflammatory vasculitis that primarily affects large- and medium-sized vessels. (visualdx.com)
- No definitive cause of Takayasu arteritis has been identified, but it is thought to be an IgG-mediated autoimmune vasculitis, perhaps triggered by a cross-reacting infectious agent. (visualdx.com)
- Giant cell arteritis (GCA), also known as temporal arteritis, is an uncommon form of granulomatous vasculitis that affects primarily the large and medium-sized arteries. (renalandurologynews.com)
- Other vasculitides such as polyarteritis nodosa, granulomatosis with polyangiitis (GPA, Wegener's), microscopic polyangiitis (MPA), or eosinophilic granulomatosis with polyangiitis (eGPA) and Takayasu arteritis rarely cause vasculitis of the superficial temporal artery. (renalandurologynews.com)
- Takayasu's arteritis (TAK) is a large vessel vasculitis with important infiltration of proinflammatory T cells in the aorta and its main branches, but its aetiology is still unknown. (onmedica.com)
- Background Giant cell arteritis (GCA) is the most frequent primary large-vessel vasculitis in patients aged over 50 years. (bmj.com)
Takayasu Arteritis62
- Angiography is commonly used in the diagnosis of Takayasu arteritis, especially in the advanced stages of the disease, when arterial stenosis, occlusion, and aneurysms may be observed. (wikipedia.org)
- However, angiography is a relatively invasive investigation, exposing patients to large doses of radiation, so is not recommended for routine, long-term monitoring of disease progression in patients with Takayasu arteritis. (wikipedia.org)
- Magnetic resonance angiography is used to diagnose Takayasu arteritis in the early stages, showing changes such as the thickening of the vessel wall. (wikipedia.org)
- It is also used for long-term monitoring of disease progression in Takayasu arteritis. (wikipedia.org)
- It includes two types, temporal arteritis and Takayasu arteritis. (wikipedia.org)
- Takayasu arteritis is more common in women of Asian descent who are in their reproductive years. (wikipedia.org)
- Takayasu arteritis is an inflammatory disease that mainly affects the larger vessels such as the aorta and its surrounding branches. (wikipedia.org)
- Research focused on Takayasu arteritis in the western parts of the world remains limited. (wikipedia.org)
- In view of the chronic process and good collateral development, Raynaud's phenomenon or digital gangrene are very rare in Takayasu arteritis. (wikipedia.org)
- Although the cause of Takayasu arteritis is unknown, the condition is characterized by segmental and patchy granulomatous inflammation of the aorta and its major derivative branches. (wikipedia.org)
- Takayasu arteritis is an inflammation of large arteries such as the aorta and its major branches . (medlineplus.gov)
- The cause of Takayasu arteritis is not known. (medlineplus.gov)
- Takayasu arteritis appears to be an autoimmune condition. (medlineplus.gov)
- Treatment of Takayasu arteritis is difficult. (medlineplus.gov)
- Alomari I, Patel PM. Takayasu arteritis. (medlineplus.gov)
- Updates in pathophysiology, diagnosis and management of Takayasu arteritis. (medlineplus.gov)
- What are the racial predilections of Takayasu arteritis? (medscape.com)
- Takayasu arteritis is observed more frequently in patients of Asian or Indian descent. (medscape.com)
- Japanese patients with Takayasu arteritis have a higher incidence of aortic arch involvement. (medscape.com)
- Takayasu arteritis: advanced understanding is leading to new horizons. (medscape.com)
- Hata A, Noda M, Moriwaki R, Numano F. Angiographic findings of Takayasu arteritis: new classification. (medscape.com)
- Numano F, Kobayashi Y. Takayasu arteritis--beyond pulselessness. (medscape.com)
- Espinoza JL, Ai S, Matsumura I. New Insights on the Pathogenesis of Takayasu Arteritis: Revisiting the Microbial Theory. (medscape.com)
- The genetics of Takayasu arteritis. (medscape.com)
- Identification of multiple genetic susceptibility loci in Takayasu arteritis. (medscape.com)
- Yagi K, Kobayashi J, Yasue S, Yamaguchi M, Shiobara S, Mabuchi H. Four unrelated cases with Takayasu arteritis and CD36 deficiency: possible link between these disorders. (medscape.com)
- Onen F, Akkoc N. Epidemiology of Takayasu arteritis. (medscape.com)
- Current status of Takayasu arteritis in India. (medscape.com)
- Seyahi E. Takayasu arteritis: an update. (medscape.com)
- Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients. (medscape.com)
- Aortic Dissection in Takayasu Arteritis. (medscape.com)
- Takayasu arteritis: clinical features in 110 Mexican Mestizo patients and cardiovascular impact on survival and prognosis. (medscape.com)
- Imaging is considered the cornerstone of the diagnosis of Takayasu arteritis. (medscape.com)
- See the image of Takayasu arteritis below. (medscape.com)
- Although not a primary tool for diagnosis, radiographic manifestations have been historically described in patients with Takayasu arteritis. (medscape.com)
- [ 31 ] Collateral formation of occluded carotid arteries frequently occur and have incidentally suggested the diagnosis of Takayasu arteritis. (medscape.com)
- Typical angina in a patient with Takayasu arteritis. (nih.gov)
- Endovascular management of takayasu arteritis: is it a durable option? (nih.gov)
- Interim outcome of endovascular management of Takayasu arteritis (TA) was determined retrospectively to assess the efficacy of angioplasty and/or stenting in 24 patients with 35 lesions in the chronic inactive stage. (nih.gov)
- Takayasu arteritis presenting as postpartum cardiomyopathy. (biomedsearch.com)
- A case of Takayasu arteritis (TA) presenting as postpartum cardiomyopathy in a puerperal 26-year-old Hispanic female patient is presented. (biomedsearch.com)
- Other biologic agents that show promising benefits for treating Takayasu arteritis include tocilizumab, and rituximab. (floridahealthfinder.gov)
- Keser G, Aksu K. What is new in management of Takayasu arteritis? (floridahealthfinder.gov)
- Efficacy of biological-targeted treatments in Takayasu arteritis: multicenter, retrospective study of 49 patients. (floridahealthfinder.gov)
- Diagnosis and Assessment of Takayasu Arteritis by Multiple Biomarkers. (biomedsearch.com)
- Background: Patients with Takayasu arteritis (TA) often show recurrence under steroid treatment without an elevation of C-reactive protein (CRP). (biomedsearch.com)
- The role of mean platelet volume in patients with Takayasu arteritis [published online ahead of print June 20, (thefreedictionary.com)
- Takayasu arteritis and atherosclerosis: Illustrating the consequences of endothelial damage. (thefreedictionary.com)
- Takayasu arteritis in Mexico: a 38-year clinical perspective through literature review. (thefreedictionary.com)
- Wegener's granulomatosis and giant cell arteritis are extremely rare in India and Japan, but Takayasu arteritis is common. (thefreedictionary.com)
- average age of Takayasu arteritis was 34 years. (thefreedictionary.com)
- The demographic, clinical and prognostic features of Takayasu arteritis. (bioportfolio.com)
- The Takayasu arteritis (TA) is a rare inflammatory large vessel arteritis which often occurs women in Aisa, one of which is China. (bioportfolio.com)
- Vascular Ultrasound for monitoring of inflammatory activity in Takayasu Arteritis. (bioportfolio.com)
- Takayasu Arteritis (TA) is a rare large-vessel arteritis that primarily affects the aorta and its major branches. (bioportfolio.com)
- Takayasu arteritis in children rarely presents with pulselessness, claudication, or bruits. (visualdx.com)
- Hotchi, M. (1992) Pathological studies on Takayasu arteritis. (scirp.org)
- Soto, M. E., Espinola, N., Flores-Suarez, L.F.and Reyes, P.A. (2008) Takayasu arteritis: Clinical features in 110 Mexican Mestizo patients and cardiovascular impact on survival and prognosis. (scirp.org)
- Giant cell arteritis (GCA) and Takayasu arteritis (TA) are referred to as large vessel vasculitides. (clinicaladvisor.com)
- The clinical features of Takayasu arteritis (TA) are similar to giant cell arteritis (GCA), especially compared to patients with GCA who lack temporal artery involvement. (clinicaladvisor.com)
- Takayasu arteritis in children. (jrheum.org)
- OBJECTIVE: To retrospectively evaluate the clinical features, angiographic findings, and outcomes of children with Takayasu arteritis (TA) in Turkey. (jrheum.org)
Takayasu's Arteritis61
- In the Western world, atherosclerosis is a more frequent cause of obstruction of the aortic arch vessels than Takayasu's arteritis. (wikipedia.org)
- Due to obstruction of the main branches of the aorta, including the left common carotid artery, the brachiocephalic artery, and the left subclavian artery, Takayasu's arteritis can present as pulseless upper extremities (arms, hands, and wrists with weak or absent pulses on the physical examination) which may be why it is also commonly referred to as the "pulseless disease. (wikipedia.org)
- One rare, important feature of the Takayasu's arteritis is ocular involvement in form of visual field defects, vision loss, or retinal hemorrhage. (wikipedia.org)
- Some individuals with Takayasu's arteritis may present with only late vascular changes, without a preceding systemic illness. (wikipedia.org)
- The genetic contribution to the pathogenesis of Takayasu's arteritis is supported by the genetic association with HLA-B∗52. (wikipedia.org)
- About 200,000 genetic variants were genotyped in two ethnically divergent Takayasu's arteritis cohorts from Turkey and North America by using a custom-designed genotyping platform (Immunochip). (wikipedia.org)
- In addition, a genetic association was identified and confirmed between Takayasu's arteritis and the FCGR2A/FCGR3A locus on chromosome 1 (rs10919543, OR = 1.81, p = 5.89 × 10-12). (wikipedia.org)
- Non-glucocorticoid drugs for the treatment of Takayasu's arteritis: A systematic review and meta-analysis. (medlineplus.gov)
- Aggarwal A, Chag M, Sinha N, Naik S. Takayasu's arteritis: role of Mycobacterium tuberculosis and its 65 kDa heat shock protein. (medscape.com)
- Kumar Chauhan S, Kumar Tripathy N, Sinha N, Singh M, Nityanand S. Cellular and humoral immune responses to mycobacterial heat shock protein-65 and its human homologue in Takayasu's arteritis. (medscape.com)
- Clinical characteristics and outcomes of Takayasu's arteritis: analysis of 108 patients using standardized criteria for diagnosis, activity assessment, and angiographic classification. (medscape.com)
- Quality of life in patients with Takayasu's arteritis is impaired and comparable with rheumatoid arthritis and ankylosing spondylitis patients. (medscape.com)
- Takayasu's arteritis is a chronic (long-term) disease in which arteries become inflamed. (harvard.edu)
- In most cases, Takayasu's arteritis targets the aorta and its major branches, including arteries to the brain, arms and kidneys. (harvard.edu)
- Over time, Takayasu's arteritis can cause scarring, narrowing and abnormal ballooning of involved blood vessels. (harvard.edu)
- In Takayasu's arteritis, the inflammation damages the aorta - the large artery that carries blood from your heart to the rest of your body - and its main branches. (mayoclinic.org)
- Takayasu's arteritis can also lead to arm or chest pain, high blood pressure, and eventually heart failure or stroke. (mayoclinic.org)
- If you don't have symptoms, you may not need treatment for Takayasu's arteritis. (mayoclinic.org)
- The signs and symptoms of Takayasu's arteritis often occur in two stages. (mayoclinic.org)
- Early detection of Takayasu's arteritis is key to getting effective treatment. (mayoclinic.org)
- If you've already been diagnosed with Takayasu's arteritis, keep in mind that your symptoms may come and go even with effective treatment. (mayoclinic.org)
- With Takayasu's arteritis, the aorta and other major arteries, including those leading to your head and kidneys, become inflamed. (mayoclinic.org)
- No one knows exactly what causes the initial inflammation in Takayasu's arteritis. (mayoclinic.org)
- Takayasu's arteritis primarily affects girls and women younger than 40. (mayoclinic.org)
- The authors (1) reported on a 48-year-old female patient who was diagnosed with Takayasu's arteritis along with a spontaneous left main coronary artery dissection. (thefreedictionary.com)
- Takayasu's arteritis accompanied with massive pericardial effusion--a case report. (thefreedictionary.com)
- The vascular abnormalities in Williams-Beuren syndrome must be distinguished from other congenital or acquired arteriopathies such as fibromuscular dysplasia or Takayasu's arteritis , respectively. (thefreedictionary.com)
- Takayasu's arteritis (TA) is a rare condition characterized by idiopathic chronic inflammation of the medium and large vessels. (hindawi.com)
- These symptoms are frequently misdiagnosed as infection 3.Takayasu's arteritis primarily affects the aorta and its primary branches 4. (bartleby.com)
- What is Takayasu's arteritis? (patientslikeme.com)
- Takayasu's Arteritis is a rare, chronic, inflammatory disease primarily of the aorta and its branches. (patientslikeme.com)
- Data from patients with Takayasu's arteritis, who reported starting treatments within the last 5 years. (patientslikeme.com)
- Takayasu's arteritis is an inflammatory disease of unknown etiology that affects the aorta and its branches. (bionity.com)
- The first case of Takayasu's arteritis was described in 1908 by Dr. Mikito Takayasu at the Annual Meeting of the Japan Ophthalmology Society. (bionity.com)
- The other half of patients with Takayasu's arteritis present with only late vascular changes, without an antecedent systemic illness. (bionity.com)
- The great majority of patients with Takayasu's arteritis respond to prednisone . (bionity.com)
- About 20 percent of patients, especially those with Takayasu's arteritis, require surgery to bypass portions of arteries narrowed by the disease or to repair aneurysms caused by the disease. (uvahealth.com)
- Takayasu's arteritis: associated inflammatory diseases. (medworm.com)
- Symptomatic pulmonary artery stenosis is a relatively uncommon manifestation of Takayasu's arteritis. (massgeneral.org)
- A few studies have shown that percutaneous angioplasty and stent implantation is a safe and effective treatment in patients with pulmonary stenosis caused by Takayasu's arteritis (2,3). (massgeneral.org)
- Endovascular stent implantation for severe pulmonary artery stenosis in aortoarteritis (Takayasu's arteritis). (massgeneral.org)
- Qin L, Hong-Liang Z, Zhi-Hong L, Chang-Ming X, Xin-Hai N. Percutaneous transluminal angioplasty and stenting for pulmonary stenosis due to Takayasu's arteritis: clinical outcome and four-year follow-up. (massgeneral.org)
- To the editor: The prospective analysis by Shelhamer and colleagues (1) of 20 patients seen at the National Institute of Health is a valuable contribution to the study of Takayasu's arteritis. (annals.org)
- Patterns of Arterial Disease in Takayasu's Arteritis and Giant Cell Arteritis. (bioportfolio.com)
- To identify and validate, using computer-driven methods, patterns of arterial disease in Takayasu's arteritis (TAK) and giant cell arteritis (GCA). (bioportfolio.com)
- Takayasu's arteritis - frontal MRI of the abdomen. (sciencephoto.com)
- Takayasu's arteritis ( disease of the pulseless women ) is a rare pathology found in young, mainly asian, women characterized by stenosis of the large and medium-sized arteries, most commonly the aorta. (sciencephoto.com)
- Diagnostic Confirmation: Are you sure your patient has Takayasu's Arteritis? (clinicaladvisor.com)
- The diagnosis of Takayasu's arteritis can be confirmed with the American College of Rheumatology's (ACR) classification criteria. (clinicaladvisor.com)
- Takayasu's arteritis is primarily a disease of adolescent girls and young women, who account for 80-90% of cases. (clinicaladvisor.com)
- C. History Part 3: Competing diagnoses that can mimic Takayasu's Arteritis. (clinicaladvisor.com)
- The differential diagnosis of Takayasu's arteritis is divided into several categories. (clinicaladvisor.com)
- Takayasu's arteritis is a chronic inflammatory arteritis involving the great vessels with predominance in aorta and its main branches. (sld.cu)
- Mycobacterium tuberculosis in the aorta of a patient with takayasu's arteritis. (scirp.org)
- Takayasu's arteritis (TA), of unknown etiology, has been related with Mycobacterium tuberculosis infection. (scirp.org)
- The possibility that Takayasu's arteritis is an extra pulmonary tu-berculosis must be explored. (scirp.org)
- Pantell, R.H. and Goodman, B.W., Jr. (1981) Takayasu's arteritis: The relationship with tuberculosis. (scirp.org)
- Robles, M. and Reyes, P.A. (1994) Takayasu's arteritis in Mexico: A clinical review of 44 consecutive cases. (scirp.org)
- 2009) Absence of Mycobacterium tuberculosis in arterial lesions from patients with Takayasu's arteritis. (scirp.org)
- 2008) Simultaneous occurrence of diffuse Takayasu's arteritis and severe disseminated tuberculosis. (scirp.org)
- Targeting JAK/STAT pathway in Takayasu's arteritis. (onmedica.com)
Cranial12
- Cranial ultrasound for the diagnosis of giant cell arteritis. (medscape.com)
- Formed visual hallucinations: a symptom of cranial arteritis. (bmj.com)
- Hart C. T. . Formed visual hallucinations: a symptom of cranial arteritis. (bmj.com)
- Also known as cranial or giant-cell arteritis, this painful condition is twice as common in women than in men and usually occurs in people ages 50 or older. (sharecare.com)
- Temporal arteritis is also called giant cell arteritis or cranial arteritis. (thefreedictionary.com)
- Cranial arteritis and giant cell arteritis are also used to refer to temporal arteritis. (mightyguide.net)
- Temporal arteritis (also called cranial or giant cell arteritis) is an inflammation of the temporal artery (which runs over the temple, beside the eye). (cureresearch.com)
- Unfortunately, Mary experiences total loss of vision in her right eye four days later, prompting an urgent visit to her eye doctor, who makes the diagnosis of cranial arteritis with optic nerve damage due to loss of blood flow. (patriotledger.com)
- Cranial Arteritis (also known as temporal arteritis or giant cell arteritis ) is an inflammatory disorder of blood vessels of unknown cause, which is seen primarily in patients over 50, and which can cause blindness as well as strokes. (patriotledger.com)
- Patients in this age group should take care to report any visual symptoms in association with headache, but for some Cranial Arteritis patients, the first sign of visual involvement is blindness, so it is essential that screening blood test be performed promptly for all older patients who present with new, unexplained headaches. (patriotledger.com)
- The temporal arteries on the side of the head are most commonly affected and, for this reason, the condition is also known as temporal arteritis or cranial arteritis. (southerncross.co.nz)
- Giant Cell Arteritis, also called Temporal or Cranial Arteritis, is an autoimmune disease that leads to the inflammation of the arteries. (healthadel.com)
Arteries31
- Arteritis is the inflammation of the walls of arteries, usually as a result of infection or autoimmune response. (wikipedia.org)
- Temporal arteritis, the second type of giant cell arteritis, is also a chronic, inflammatory disease involving mid- to large-sized arteries. (wikipedia.org)
- Color Doppler ultrasound of the temporal arteries--a new method for diagnosing temporal arteritis]. (medscape.com)
- Color Doppler sonography of the temporal arteries in giant cell arteritis and polymyalgia rheumatica. (medscape.com)
- Diamantopoulos AP, Haugeberg G, Hetland H, Soldal DM, Bie R, Myklebust G. The diagnostic value of color Doppler ultrasonography of temporal arteries and large vessels in giant cell arteritis: A consecutive case series. (medscape.com)
- Giant cell arteritis is a disorder that causes inflammation of your arteries, usually in the scalp, neck, and arms. (medlineplus.gov)
- Giant cell arteritis is a result of inflammation of arteries. (medicinenet.com)
- Because giant cell arteritis is commonly due to inflammation of the arterial blood vessels affecting the head, it frequently leads to headaches , pain in the jaw when repetitively chewing, and tenderness of the scalp (usually over the inflamed arteries of the sides of the head). (medicinenet.com)
- When the arteries affected by giant cell arteritis become inflamed, they can narrow to the degree that the blood flow through them is limited. (medicinenet.com)
- GCA is sometimes referred to as temporal arteritis, as one of the more commonly affected arteries is the temporal artery at the side of your forehead (temple). (rnib.org.uk)
- Temporal arteritis shows a predilection for the vertebral arteries, the subclavian arteries, and the extracranial branches of the carotid arteries (ie, the superficial temporal, ophthalmic, occipital, and posterior ciliary arteries). (medscape.com)
- Giant cell arteritis is an inflammation of the lining of your arteries. (mayoclinic.org)
- With giant cell arteritis, the lining of arteries becomes inflamed. (mayoclinic.org)
- 1 Temporal arteritis causes inflammation of medium- to large-sized arteries, particularly branches of the carotid artery. (mja.com.au)
- Classically, temporal arteritis presents as a recent-onset headache with scalp tenderness over the temporal arteries. (mja.com.au)
- Colour duplex sonography of temporal arteries before decision for biopsy: a prospective study in 55 patients with suspected giant cell arteritis. (portsmouthhospital.com)
- 1- 13 It is a large and medium sized granulomatous arteritis, especially involving the extracranial branches of the carotid arteries. (bmj.com)
- A severe, constant headache may be one of the first signs of temporal arteritis, a condition caused by inflammation of the large temporal arteries located on either side of the head. (sharecare.com)
- The term temporal arteritis literally means 'inflammation of the temporal arteries. (thefreedictionary.com)
- Temporal arteritis is inflammation of the arteries. (doctors-hospital.net)
- Temporal arteritis is a grave disorder which results in inflammation of the medium and large arteries within the head. (mightyguide.net)
- The temporal arteries are usually affected by temporal arteritis. (mightyguide.net)
- Primarily affecting arteries in the head, neck and eyes - as well as the aorta and its primary branches - giant cell arteritis, also called temporal arteritis, is an important cause of irreversible blindness. (eurekalert.org)
- Blindness, which affects up to 20 percent of giant cell arteritis patients, can result from inflammation of the arteries supplying the optic nerve and the retina. (eurekalert.org)
- Salvarani and colleagues (1) described their experience with color Doppler ultrasonography of the temporal arteries in patients with polymyalgia rheumatica and giant-cell arteritis. (annals.org)
- Temporal arteritis (Horton's disease) is a condition in which medium and large arteries, usually in the head and neck, become inflammed. (sciencephoto.com)
- Giant cell arteritis (GCA) is a common inflammation disease of medium- to large-sized arteries. (shoppersdrugmart.ca)
- Giant cell arteritis is an inflammatory condition affecting arteries of the upper body and head. (southerncross.co.nz)
- Note that arteritis is an inflammation of the arteries that comes on over a fairly short period of time, which is different from atherosclerosis, which is hardening of the arteries that occurs gradually. (canada.com)
- Prevalence and distribution of VZV in temporal arteries of patients with giant cell arteritis. (neurology.org)
- Giant Cell Arteritis can affect one, or both temporal arteries. (healthadel.com)
Polymyalgia Rheumatica and Giant Cell Arte1
- Diagnosis and management of polymyalgia rheumatica and giant cell arteritis, including American College of Rheumatology criteria for a diagnosis, recommended corticosteroid therapy and potential side-effects of treatment. (gponline.com)
Incidence9
- Temporal arteritis has a higher incidence in people of Scandinavian descent. (wikipedia.org)
- Giant cell arteritis is a disease of elderly persons, the incidence of which increases with increasing age. (medscape.com)
- To analyze the incidence of biopsy-confirmed giant cell arteritis among black and white patients, Gruener and colleagues conducted a retrospective review of all patients who underwent temporal artery biopsy at the Johns Hopkins Wilmer Eye Institute, in Baltimore, from July 1, 2007, through Sept. 30, 2017. (healio.com)
- The primary outcome was the estimated incidence rates of biopsy-confirmed giant cell arteritis among black and white patients. (healio.com)
- Crude annual incidence rates for biopsy-confirmed giant cell arteritis were 2.9 (95% CI, 1.3-5.5) per 100,000 among black patients, compared with 4.2 (95% CI, 3.0-5.6) per 100,000 for white patients. (healio.com)
- Various sources and calculations are available in statistics about Temporal arteritis , prevalence and incidence statistics for Temporal arteritis , and you can also research other medical statistics in our statistics center . (cureresearch.com)
- Do solar cycles influence giant cell arteritis and rheumatoid arthritis incidence? (osti.gov)
- Our objective was to examine the influence of solar cycle and geomagnetic effects on the incidence of giant cell arteritis (GCA) and rheumatoid arthritis (RA). (osti.gov)
- The incidence of giant cell arteritis increases with age. (southerncross.co.nz)
Known as temporal arteritis3
- Giant cell arteritis (GCA), also known as temporal arteritis, is a condition that can be a great threat to your sight. (rnib.org.uk)
- Giant cell arteritis is also known as temporal arteritis. (reference.com)
- Giant cell arteritis (GCA) - also known as temporal arteritis (TA) - is a potentially life-threatening autoimmune condition. (roche.com)
Inflammatory7
- In GCA, the artery walls become inflamed (arteritis) with large inflammatory cells (giant cells). (rnib.org.uk)
- Inflammatory arteritis is inflammation of the aorta, the body's largest artery that carries blood from the heart to the rest of the body. (uvahealth.com)
- Inflammatory arteritis can cause blockages in the aorta or aneurysms. (uvahealth.com)
- Disorders in connective tissue, such as ligaments and tendons, can cause inflammatory arteritis. (uvahealth.com)
- This, despite the fact that we have had glucocorticoids as the standard of care treatment for giant cell arteritis, as a corner stone of so many of our other inflammatory diseases. (healio.com)
- Giant cell arteritis (GCA) or temporal arteritis is an inflammatory condition that mainly affects the blood vessels in your head. (arthritisresearchuk.org)
- Sufferers can also ingest anti-inflammatory drugs like Ibuprofen to relieve temporal arteritis symptoms, however these over the counter drugs, won't cure the diseases or lower the risk factors. (healthadel.com)
Establishing the diagnosis of temporal arteritis1
- Temporal artery biopsy is the criterion standard for establishing the diagnosis of temporal arteritis. (medscape.com)
Chronic2
- OTCQX: RHHBY) announced today that the Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending approval of Actemra®/RoActemra® (tocilizumab) for the treatment of giant cell arteritis (GCA), a chronic and potentially life-threatening autoimmune condition. (roche.com)
- OTCQX: RHHBY), announced today that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation status to Actemra/RoActemra® (tocilizumab) for giant cell arteritis (GCA), a chronic, potentially life-threatening autoimmune condition. (roche.com)
Criteria for diagnosing gian1
- An international expert in giant cell arteritis and polymyalgia rheumatica, Professor Dasgupta is well known for his ground-breaking work on establishing criteria for diagnosing giant cell arteritis (GCA). (abebooks.com)
Patients with suspected giant cell arte3
- What is the maximum recommended delay for obtaining a temporal artery biopsy after initiation of corticosteroids in patients with suspected giant cell arteritis? (aafp.org)
- Corticosteroid therapy in patients with suspected giant cell arteritis should not degrade the accuracy of temporal artery biopsy if the biopsy is performed within four weeks of corticosteroid initiation. (aafp.org)
- A retrospective case-control study in 2012 evaluated 335 patients with suspected giant cell arteritis, 81 of whom had a positive temporal artery biopsy. (aafp.org)
20161
- 2016) Allelic Variation in CXCL16 Determines CD3+ T Lymphocyte Susceptibility to Equine Arteritis Virus Infection and Establishment of Long-Term Carrier State in the Stallion. (eurekalert.org)
Giant Cell Arteritis Sym1
- What are giant cell arteritis symptoms and signs? (medicinenet.com)
Similar to giant cell arte1
- This condition has many features that are similar to giant cell arteritis or temporal arteritis in older people. (medlineplus.gov)
Biopsy-proven giant cell arte2
- Contrary to widespread belief that biopsy-proven giant cell arteritis is comparatively rare among black patients, researchers found the condition occurs at a similar rate among black and white patients, according to data published in JAMA Ophthalmology . (healio.com)
- Prevalence of a normal c-reactive protein with an elevated erythrocyte sedimentation rate in biopsy-proven giant cell arteritis. (doctors-hospital.net)
Suffer from temporal arteritis2
- About 20 out of 100,000 people over the age of 50 suffer from temporal arteritis. (thefreedictionary.com)
- Women are three times more likely to suffer from temporal arteritis. (healthadel.com)
Symptoms of temporal arteritis3
- Symptoms of temporal arteritis are classified as specific and nonspecific. (wikipedia.org)
- Symptoms of temporal arteritis can be either constitutional or vascular-related. (medscape.com)
- Further information about the symptoms of Temporal arteritis is available including a list of symptoms of Temporal arteritis , other diseases that might have similar symptoms in differential diagnosis of Temporal arteritis , or alternatively return to research other symptoms in the symptom center . (cureresearch.com)
Development of giant cell arte1
- In the impressive nested case-control study recently published in the Annals of the Rheumatic Diseases, 2 Rhee et al examined the relationship between any infection or herpes zoster infection and the development of giant cell arteritis (GCA) in a large cohort of patients (n=4559) and controls (n=22 759). (bmj.com)
Affects2
- The most common symptoms of giant cell arteritis are head pain and tenderness - often severe - that usually affects both temples. (mayoclinic.org)
- Giant cell arteritis affects adults only, and rarely those under 50. (mayoclinic.org)
Treatment17
- It is often associated with aneurysms and Hepatitis B. The first-line treatment for arteritis is oral glucocorticoid (steroid) medication, such as prednisone, taken daily for a period of three months. (wikipedia.org)
- What is the treatment for giant cell arteritis? (rnib.org.uk)
- Patients should seek immediate medical attention when symptoms of giant cell arteritis appear to ensure early diagnosis and treatment of the condition. (reference.com)
- Over the past 30 years, 49 articles on giant cell arteritis (GCA) have been published in the Journal of Neuro-Ophthalmology, highlighting the diverse presentations of patients, discussing controversies in diagnosis and treatment, and reviewing prognosis. (lww.com)
- Prompt treatment with corticosteroid medications usually relieves symptoms of giant cell arteritis and may prevent loss of vision. (mayoclinic.org)
- If you're diagnosed with giant cell arteritis, starting treatment as soon as possible can usually help prevent vision loss. (mayoclinic.org)
- The specialist then put her on pregnasone treatment ( I can't remember the doseage but i think it was about 60- 80 mg a day ) and they did the biopsy to determine it was in fact temporal arteritis. (medhelp.org)
- The typical symptoms and findings of giant cell arteritis (GCA) are still too often misinterpreted, and urgently needed treatment is delayed. (aerzteblatt.de)
- Jover JA, Hernandez-Garcia C, Morado IC, Vargas E, Banares A, Fernandez-Gutierrez B. Combined treatment of giant-cell arteritis with methotrexate and prednisone. (cmaj.ca)
- The role of corticosteroid-sparing agents such as methotrexate in the treatment of temporal arteritis has remained unclear. (cmaj.ca)
- GiACTA (NCT01791153) is a phase III, global, randomised, double-blind, placebo-controlled trial investigating the efficacy and safety of Actemra / RoActemra (tocilizumab) as a novel treatment for giant cell arteritis (GCA). (roche.com)
- Phase 3 results for tocilizumab (Actemra), a novel interleukin-6 (IL-6) receptor antagonist , shows it outperforms steroid-only treatment for treatment of giant cell arteritis. (aao.org)
- Based on the results of numerous case studies and the 2 randomized control trials, tocilizumab is the first agent to be approved by the Food and Drug Administration for treatment of giant cell arteritis. (ovid.com)
- So, once a diagnosis of giant cell arteritis has been made, treatment is started as soon as possible in order to reduce the risk of complications. (southerncross.co.nz)
- Giant cell arteritis (GCA) is treatable, and complications can be avoided when treatment is started early enough. (canada.com)
- Compared with healthy subjects, aortic distensibility and aortic strain are decreased in patients with giant cell arteritis before initiation of corticosteroid treatment. (bmj.com)
- GSK today announced that dosing has commenced in a phase III study evaluating sirukumab, a human anti-interleukin (IL)-6 monoclonal antibody, for the treatment of patients with giant cell arteritis (GCA). (gsk.com)
Equine arteritis virus2
- Equine arteritis virus can be efficiently spread through artificial insemination (AI) and the use of raw, cooled-transported or frozen semen. (aaep.org)
- Identification of CXCL16 as a determinant of equine arteritis virus persistent infection in the stallion. (eurekalert.org)
Headache1
- Headache caused by giant cell arteritis. (springer.com)
Corticosteroid2
- To treat giant cell arteritis, doctors prescribe corticosteroid drugs, which fight inflammation, explains Mayo Clinic. (reference.com)
- Brief Summary: Primary Objective: To evaluate the efficacy of sarilumab in patients with giant cell arteritis (GCA) as assessed by the proportion of patients with sustained remission for sarilumab compared to placebo, in combination with a corticosteroid (CS) tapering course. (vasculitisfoundation.org)
Severe1
- An obliterative arteritis of the branches of the aortic arch results in severe ocular and cerebral damage. (ahajournals.org)
Vascular1
- The net effect of these events is an arteritis with local vascular destruction and intimal hyperplasia leading to luminal stenosis and occlusion. (medscape.com)
Occurs4
- Giant cell arteritis occurs in 10%-15% of patients with polymyalgia rheumatica . (medicinenet.com)
- Temporal arteritis occurs in 3 histologic patterns: classic, atypical, and healed. (medscape.com)
- Other symptoms of giant cell arteritis include vision loss, fever and jaw claudication, which usually occurs when chewing or opening the mouth widely. (reference.com)
- Temporal arteritis almost always occurs in people over 50, and it becomes more common as people age. (thefreedictionary.com)