Artemisia annua: A plant species of the genus ARTEMISIA, family ASTERACEAE. It is the source of the antimalarial artemisinin (ANTIMALARIALS).Artemisia: A plant genus of the family ASTERACEAE with strong-smelling foliage. It is a source of SANTONIN and other cytotoxic TERPENES.Perfume: A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell, especially a fluid containing fragrant natural oils extracted from flowers, woods, etc., or similar synthetic oils. (Random House Unabridged Dictionary, 2d ed)Artemisinins: A group of SESQUITERPENES and their analogs that contain a peroxide group (PEROXIDES) within an oxepin ring (OXEPINS).Cosmetics: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)SesquiterpenesPlant Leaves: Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)Asteraceae: A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of "daisy" refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.Plasmodium falciparum: A species of protozoa that is the causal agent of falciparum malaria (MALARIA, FALCIPARUM). It is most prevalent in the tropics and subtropics.Malaria, Cerebral: A condition characterized by somnolence or coma in the presence of an acute infection with PLASMODIUM FALCIPARUM (and rarely other Plasmodium species). Initial clinical manifestations include HEADACHES; SEIZURES; and alterations of mentation followed by a rapid progression to COMA. Pathologic features include cerebral capillaries filled with parasitized erythrocytes and multiple small foci of cortical and subcortical necrosis. (From Adams et al., Principles of Neurology, 6th ed, p136)Western Australia: A state in western Australia. Its capital is Perth. It was first visited by the Dutch in 1616 but the English took possession in 1791 and permanent colonization began in 1829. It was a penal settlement 1850-1888, became part of the colonial government in 1886, and was granted self government in 1890. (From Webster's New Geographical Dictionary, 1988, p1329)Artemisia absinthium: A plant species of the genus ARTEMISIA, family ASTERACEAE that has been used in ABSINTHE. The oil contains neurotoxic 1-thujone and d-isothujone.Baths: The immersion or washing of the body or any of its parts in water or other medium for cleansing or medical treatment. It includes bathing for personal hygiene as well as for medical purposes with the addition of therapeutic agents, such as alkalines, antiseptics, oil, etc.Tea: The infusion of leaves of CAMELLIA SINENSIS (formerly Thea sinensis) as a beverage, the familiar Asian tea, which contains CATECHIN (especially epigallocatechin gallate) and CAFFEINE.Smell: The ability to detect scents or odors, such as the function of OLFACTORY RECEPTOR NEURONS.Disinfectants: Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)Surgery, Veterinary: A board-certified specialty of VETERINARY MEDICINE, requiring at least four years of special education, training, and practice of veterinary surgery after graduation from veterinary school. In the written, oral, and practical examinations candidates may choose either large or small animal surgery. (From AVMA Directory, 43d ed, p278)Cyclization: Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Alkyl and Aryl Transferases: A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (excluding methyl groups). EC 2.5.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Melissa: A plant genus of the family LAMIACEAE. The common names of beebalm or lemonbalm are also used for MONARDA.Punicaceae: A plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida that is a small family with a single genus.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Weather: The state of the ATMOSPHERE over minutes to months.Plants, Medicinal: Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.Epimedium: A plant genus of the family BERBERIDACEAE which is used in DRUGS, CHINESE HERBAL. Members contain flavonol glycosides including epimedins, icariin and noricariin.Drugs, Chinese Herbal: Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.Medicine, Chinese Traditional: A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.Podophyllum: A genus of poisonous American herbs, family BERBERIDACEAE. The roots yield PODOPHYLLOTOXIN and other pharmacologically important agents. The plant was formerly used as a cholagogue and cathartic. It is different from the European mandrake, MANDRAGORA.Chenopodium: A plant genus in the CHENOPODIACEAE family.

Cloning and functional characterization of a beta-pinene synthase from Artemisia annua that shows a circadian pattern of expression. (1/50)

Artemisia annua plants produce a broad range of volatile compounds, including monoterpenes, which contribute to the characteristic fragrance of this medicinal species. A cDNA clone, QH6, contained an open reading frame encoding a 582-amino acid protein that showed high sequence identity to plant monoterpene synthases. The prokaryotically expressed QH6 fusion protein converted geranyl diphosphate to (-)-beta-pinene and (-)-alpha-pinene in a 94:6 ratio. QH6 was predominantly expressed in juvenile leaves 2 weeks postsprouting. QH6 transcript levels were transiently reduced following mechanical wounding or fungal elicitor treatment, suggesting that this gene is not directly involved in defense reaction induced by either of these treatments. Under a photoperiod of 12 h/12 h (light/dark), the abundance of QH6 transcripts fluctuated in a diurnal pattern that ebbed around 3 h before daybreak (9th h in the dark phase) and peaked after 9 h in light (9th h in the light phase). The contents of (-)-beta-pinene in juvenile leaves and in emitted volatiles also varied in a diurnal rhythm, correlating strongly with mRNA accumulation. When A. annua was entrained by constant light or constant dark conditions, QH6 transcript accumulation continued to fluctuate with circadian rhythms. Under constant light, advanced cycles of fluctuation of QH6 transcript levels were observed, and under constant dark, the cycle was delayed. However, the original diurnal pattern could be regained when the plants were returned to the normal light/dark (12 h/12 h) photoperiod. This is the first report that monoterpene biosynthesis is transcriptionally regulated in a circadian pattern.  (+info)

Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). (2/50)

Artemisia annua L. (annual wormwood) contains the antimalarial artemisinin. Aqueous preparations of the dried herb are included in the pharmacopoeia of the People's Republic of China for treatment of fever and malaria. Fourteen healthy male volunteers received one liter of tea prepared from nine grams of Artemisia annua leaves. Blood samples were taken and artemisinin was detected by reversed phase high-performance liquid chromatography. The mean +/- SD maximum plasma concentration of artemisinin was 240 +/- 75 ng/mL and the mean +/- SD area under the plasma concentration-time curve was 336 +/- 71 ng/mL x hr. Artemisinin was absorbed faster from herbal tea preparations than from oral solid dosage forms, but bioavailability was similar. One liter of an aqueous preparation of nine grams of Artemisia annua contained 94.5 milligrams of artemisinin (approximately 19% of the usually recommended daily dose). Artemisinin plasma concentrations after intake of this herbal tea are sufficient for clinical effects, but insufficient to recommend such preparations as equivalent substitutes for modern artemisinin drugs in malaria therapy.  (+info)

Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin. (3/50)

Artemisinin, a sesquiterpene lactone endoperoxide derived from the plant Artemisia annua, forms the basis of the most important treatments of malaria in use today. In an effort to elucidate the biosynthesis of artemisinin, an expressed sequence tag approach to identifying the relevant biosynthetic genes was undertaken using isolated glandular trichomes as a source of mRNA. A cDNA clone encoding a cytochrome P450 designated CYP71AV1 was characterized by expression in Saccharomyces cerevisiae and shown to catalyze the oxidation of the proposed biosynthetic intermediates amorpha-4,11-diene, artemisinic alcohol and artemisinic aldehyde. The identification of the CYP71AV1 gene should allow for the engineering of semi-synthetic production of artemisinin in appropriate plant or microbial hosts.  (+info)

Ensuring sustained ACT production and reliable artemisinin supply. (4/50)

INTRODUCTION: This paper reviews recent trends in the production, supply and price of the active ingredients as well as finished ACT products. Production and cost data provided in this paper are based on an ongoing project (Artepal). Stability data are derived from a development project on rectal artesunate. DISCUSSION: The artemisinin raw material and its derivatives appear to be very stable compared to the finished products. Supply of artemisinin changed in May 2004 when the Global Fund shifted financial support to qualified countries from chloroquine or sulphadoxine-pyrimethamine to an ACT for treatment of malaria. First, there was a sudden shortage of the starting material, and short term scarcity led to a steep rise in API price: it increased dramatically in 2004, from $350 per kg to more than $1000. Second, there was a parallel increase in the number of companies extracting artemisinin from 10 to 80 between 2003 and 2005 in China, and from 3 to 20 in Vietnam. Commercial cultivation began also in East Africa and Madagascar.A steady and predictable demand for the crop can eliminate such wide fluctuations and indirectly contribute to price stability of the herb, the API and ACT. With appropriate mechanisms to reduce those fluctuations, the cost of artemisinin might decrease sustainably to US$ 250-300 per kg. CONCLUSION: Today the global health community is facing the risk of another cyclical swing with lower demand feeding into reduced planting of A. annua and, thereafter, a new shortage of the raw material and higher API prices. International donors, the largest purchasers for ACTs could better coordinate their activities, in order to guarantee purchase of ACTs and consequently of API with manufacturers. In parallel, the base of quality producers of APIs and finished ACT products needs to be broadened.While the ACT programme is still in its early stages, the consequences of another wave of artemisinin and ACT shortages would permanently discredit it and impede any progress in rolling malaria back.  (+info)

The rapid determination of artemisinin by post-column derivatization high-performance liquid chromatography using matrix solid-phase dispersion method. (5/50)

Artemisinin (an antimalaric compound) is isolated as the active compound of the medicinal plant Artemisia annua L. A simple, rapid, and high-efficient method of extraction is developed, in which it is extracted by matrix solid-phase dispersion (MSPD) and directly analyzed by post-column derivatization high-performance liquid chromatography (HPLC). The quantitation results from the MSPD method are compared with two conventional liquid solvent extraction processes, Soxhlet and ultrasonic wave by F-test, and the result indicates no significant difference. The production rate of Artemisinin during wild plant growth (tested over two years, acquired from Yunnan, provincial Yuan Yan country) is determined. The recovery range of determination is 88.1-91.2%. The relative standard deviation (RSD) is 4.55-6.43%. The limits of detection are 0.1 microg/mL, and the limits of quantitation are 0.5 microg/mL.  (+info)

The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua. (6/50)

 (+info)

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. (7/50)

 (+info)

Recent advances in artemisinin production through heterologous expression. (8/50)

Artemisinin the sesquiterpene endoperoxide lactone extracted from the herb Artemisia annua, remains the basis for the current preferred treatment against the malaria parasite Plasmodium falciparum. In addition, artemisinin and its derivatives show additional anti-parasite, anti-cancer, and anti-viral properties. Widespread use of this valuable secondary metabolite has been hampered by low production in vivo and high cost of chemical synthesis in vitro. Novel production methods are required to accommodate the ever-growing need for this important drug. Past work has focused on increasing production through traditional breeding approaches, with limited success, and on engineering cultured plants for high production in bioreactors. New research is focusing on heterologous expression systems for this unique biochemical pathway. Recently discovered genes, including a cytochrome P450 and its associated reductase, have been shown to catalyze multiple steps in the biochemical pathway leading to artemisinin. This has the potential to make a semi-synthetic approach to production both possible and cost effective. Artemisinin precursor production in engineered Saccharomyces cerevisiae is about two orders of magnitude higher than from field-grown A. annua. Efforts to increase flux through engineered pathways are on-going in both E. coli and S. cerevisiae through combinations of engineering precursor pathways and downstream optimization of gene expression. This review will compare older approaches to overproduction of this important drug, and then focus on the results from the newer approaches using heterologous expression systems and how they might meet the demands for treating malaria and other diseases.  (+info)

*Artemisia annua

1753 Flora of Pakistan Altervista Flora Italiana, Assenzio annuale Artemisia annua L. Anonymus. "Artemisia annua (sweet ... for Artemisia annua L. Simonnet, X.; Quennoz, M.; Carlen, C. (2006). "New Artemisia annua hybrids with high artemisinin content ... Dry leave yields of Artemisia annua plantations vary between 0.5 and 3 t/ha. Source: In terms of the climate A. annua prefers ... armoise annuelle Artemisia annua Linnaeus, Sp. Pl. 2: 847. 1753. Flora of China Vol. 20-21 Page 691 黄花蒿 huang hua hao Artemisia ...

*Wushi'er Bingfang

"Plants & Fungi: Artemisia annua". Royal Botanic Gardens, Kew. Retrieved 24 August 2013. Harper 1998, p. 272. Hsu 2006, p. 666. ...

*Wreath

ISBN 978-0-521-41441-8. Ferreira, Jorge; Janick, Jules (2009). "Data sheet about Artemisia annua" (PDF). Purdue University. ...

*List of MeSH codes (B06)

... artemisia absinthium (wd , gwp gwe g , in it p) MeSH B06.388.100.100.100.144 --- artemisia annua (wd , gwp gwe g , in it p) ... artemisia (plant) (wd , gwp gwe g , in it p) MeSH B06.388.100.100.100.099 --- ...

*List of traditional Chinese medicines

Sweet wormwood (Artemisia annua, Qing Hao) is believed under TCM to treat fever, headache, dizziness, stopping bleeding, and ... Ferreira JF, Janick J (1995). "Floral Morphology of Artemisia annua with Special Reference to Trichomes". Int. J. Plant Sci. ... 2004). "Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of ... 1 February 2004). "Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. ( ...

*Epi-cedrol synthase

Hua, L.; Matsuda, S.P. (1999). "The molecular cloning of 8-epicedrol synthase from Artemisia annua". Arch. Biochem. Biophys. ... a sesquiterpene cyclase from Artemisia annua L". Arch. Biochem. Biophys. 369: 213-222. doi:10.1006/abbi.1999.1358. PMID ...

*beta-caryophyllene synthase

"A cDNA clone for β-caryophyllene synthase from Artemisia annua". Phytochemistry. 61: 523-529. doi:10.1016/s0031-9422(02)00265-0 ...

*Amorpha-4,11-diene synthase

ADS is expressed 16-fold higher in the leaves than in roots of the Artemisia annua plant and 10-fold higher than in the stems ... Liu B, Wang H, Du Z, Li G, Ye H (2011). "Metabolic engineering of artemisinin biosynthesis in Artemisia annua L". Plant Cell ... Under normal conditions, ADS is expressed at low levels in Artemisia annua; however, when exposed to cold, heat shock, or UV ... One of the synthetic genes in this procedure is ADS from Artemisia annua. The semi-synthetic production of artemisinin by ...

*Artesunate suppositories

Artemisinins are sesquiterpene lactones isolated from Artemisia annua, a Chinese traditional medicine. The risk of death from ...

*Casticin

Found in Artemisia annua, the flavonoid has been shown to enhance the antimalarial activity of artemisinin though casticin ... Liu KC; Yang SL; Roberts MF; Elford BC; Phillipson JD (1992). "Antimalarial activity of Artemisia annua flavonoids from whole ...

*Sphingomonas endophytica

nov., isolated from Artemisia annua L". International Journal of Systematic and Evolutionary Microbiology. 62 (Pt 7): 1576-80. ... nov., isolated from Artemisia annua L". International Journal of Systematic and Evolutionary Microbiology. 62 (Pt 7): 1576-80. ... is a Gram-negative bacteria from the genus of Sphingomonas which has been isolated from the root of the plant Artemisia annua ...

*Beta-farnesene synthase

... β-farnesene synthase from Artemisia annua". Phytochemistry. 66 (9): 961-967. doi:10.1016/j.phytochem.2005.03.027. PMID 15896363 ...

*R-linalool synthase

Jia JW, Crock J, Lu S, Croteau R, Chen XY (1999). "(3R)-Linalool synthase from Artemisia annua L.: cDNA isolation, ...

*Traditional Chinese medicine

A 2013 review suggested that although the antimalarial herb Artemisia annua may not cause hepatotoxicity, haematotoxicity, or ... which is a processed extract of Artemisia annua, a herb traditionally used as a fever treatment. Researcher Tu Youyou ... "A safety assessment of the antimalarial herb Artemisia annua during pregnancy in Wistar rats". Phytotherapy Research. 27 (5): ...

*Pseudonocardia artemisiae

nov., isolated from surface-sterilized Artemisia annua L". International Journal of Systematic and Evolutionary Microbiology. ... artemisiae is a bacterium from the genus of Pseudonocardia which has been isolated from the roots of the plant Artemisia annua ...

*Artemisinin

Artemisia annua is a common herb found in many parts of the world, and has been used by Chinese herbalists for more than 2000 ... In the course of this research, Tu Youyou discovered artemisinin in the leaves of Artemisia annua (annual wormwood; 1972). The ... Artemisinin is an antimalarial lactone derived from qinghao 青蒿 (Artemisia annua or sweet wormwood). The medicinal value of this ... Artemisinin is isolated from the plant Artemisia annua, sweet wormwood, a herb employed in Chinese traditional medicine. A ...

*Project 523

Among one of the earliest examined plants was huanghuahao (sweet wormwood, or scientifically, Artemisia annua). These two ... Artemisia annua extract, called qinghao, was described vividly in the fourth-century Chinese physician Ge Hong's book Zhouhou ...

*Altechromone A

... and Endophyte of Artemisia annua". Journal of Natural Products. 1. 70 (1): 114-117. doi:10.1021/np0604127. PMID 17253861. ...

*Ian A. Graham

Characterisation and genetic mapping of traits responsible for production of artemisinin in Artemisia annua has enabled ... "The Genetic Map of Artemisia annua L. Identifies Loci Affecting Yield of the Antimalarial Drug Artemisinin". Science. 327 (5963 ...

*Artemisinic aldehyde Delta11(13)-reductase

H+ This enzyme i present in Artemisia annua. Bertea, C.M.; Freije, J.R.; van der Woude, H.; Verstappen, F.W.; Perk, L.; Marquez ... reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua". J. Biol. Chem. 283 (31 ... "Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua". Planta ...

*Streptomyces endophyticus

nov., an endophytic actinomycete isolated from Artemisia annua L". International Journal of Systematic and Evolutionary ... nov., an endophytic actinomycete isolated from Artemisia annua L". International Journal of Systematic and Evolutionary ... is a bacterium species from the genus of Streptomyces which has been isolated from roots of the plant Artemisia annua L. in ...

*Streptomyces artemisiae

nov., isolated from surface-sterilized tissue of Artemisia annua L". International Journal of Systematic and Evolutionary ... nov., isolated from surface-sterilized tissue of Artemisia annua L". International Journal of Systematic and Evolutionary ... artemisiae is a bacterium species from the genus of Streptomyces which has been isolated from the plant Artemisia annua L. in ...

*Artemotil

It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. It is currently only ...

*Plant use of endophytic fungi in defense

... colonization on terpene emission and content of Artemisia annua L". Plant Biol. 10 (1): 108-122. doi:10.1055/s-2007-964963. ...

*Tu Youyou

By 1971, her team had made 380 extracts from 200 herbs, and discovered the extracts from qinghao (Artemisia annua, sweet ... One compound was effective, sweet wormwood (Artemisia annua), which was used for "intermittent fevers," a hallmark of malaria. ... Artemisia annua L). Weise, Elizabeth (12 September 2011). "'America's Nobel' awarded to Chinese scientist". USA Today. ...

*beta-pinene synthase

"Cloning and functional characterization of a β-pinene synthase from Artemisia annua that shows a circadian pattern of ...
INTRODUCTION. Artemisia annua L. (Asteraceae) is an aromatic annual herb native to China and acclimatized in Brazil (Marchese & Rehder, 2001; Marchese et al., 2005). The herbs leaves are a source of artemisinin, a sesquiterpene lactone effective against resistant strains of Plasmodium falciparum that cause cerebral malaria (Ferreira & Janick, 1996) and are selectively cytotoxic to cancer cells (Ferreira, 2004; Efferth, 2007). Additionally, this species is a source of essential oil, which is commercially used in the perfume and cosmetic industries (Jain et al., 1996; Magalhães et al., 2004).. The herbs low yields of artemisinin have been the limiting factor for artemisinins large-scale isolation (Charles & Simon, 1990). Thus, breeding programs for A. annua seek to select late-flowering genotypes with high artemisinin contents and high leaf biomass production, which facilitates an increase in the production of artemisinin from 5 kg ha-1 to 25 kg ha-1 (Magalhães et al., 1997, 1999). Studies ...
The sweet wormwood is a traditional Chinese medicinal plant that has become known in recent times as a promising antimalaria drug. he Latin name Artemisia annua already refers to the fact that the plant grows annual. It can be found as a weed in the
Huzhou Purestar Biochem Co.,Ltd is provide the reliable quality Sweet Wormwood Extract,Artemisia Annua Extract,Artemisinine with ISO,KOSHER,HALAL.
Terpene synthases (TPSs) are responsible for the extremely diversified and complex structure of terpenoids. Amorpha-4,11-diene synthase (ADS) has a high (90%) fidelity in generating the sesquiterpene precursor for the biosynthesis of artemisinin, an antimalarial drug, however, little is known about how active site residues of ADS are involved in carbocation rearrangement and cyclization reactions. Here, we identify seven residues that are key to most of the catalytic steps in ADS. By structural modeling and amino acid sequence alignments of ADS with two functionally relevant sesquiterpene synthases from Artemisia annua, we performed site-directed mutagenesis and found that a single substitution, T296V, impaired the ring closure activity almost completely, and tetra-substitutions (L374Y/L404V/L405I/G439S) led to an enzyme generating 80% monocyclic bisabolyl-type sesquiterpenes, whereas a double mutant (T399L/T447G) showed compromised activity in regioselective deprotonation to yield 34.7 and ...
Dear All,. It is interesting reading the debate on malaria, Artemisia annua and ARTAVOL.. First I want to say I live in uganda in Africa where malaria is a problem and I used to suffer from malaria four times a year. I want to put it clear that in 2006 I investigated use of Artemisia tea for malaria prevention in two large farm groups, one in KIGO tea farm in western Uganda and another in Wagagai flower farm in central Uganda near Entebbe airport and found that the Artemisia tea reduced fever cases among the users by over 80% but this was not controlled clinical trial.. So in 2008 I submitted a proposal to the government of Uganda to fund us to investigate the effectiveness and safety of Artemisia tea in prevention of malaria using Randomised control trial method. We conducted the study for 12 months and proved that Artemisia tea taken regularly does not just reduce fever cases by more than 80% but actually brings malaria cases to 0% by the eigth month of intake.. This work has been published in ...
Geography and distribution Native to Eurasia, from south-east Europe (including Albania, Bulgaria, Montenegro, Romania, Russia, Serbia, Turkey) to Vietnam and northern India. Naturalised in many countries (including Argentina, Austria, the Czech Republic, France, Germany, Hungary, Italy, Poland, Slovakia, Spain, Switzerland and the United States). It has even been occasionally recorded growing wild in the UK, arising from bird seed or wool shoddy, and has been cultivated experimentally as far north as Finland. Description Overview: Sweet wormwood is a single-stemmed, hairless, sweetly aromatic annual growing up to 1 m high (2 m in cultivation). The stem is erect, ribbed and brownish or violet-brown. Leaves: The basal leaves are 3-pinnatisect (divided three times into deeply cut leaflets), 3-5 cm long and 2-4 cm wide; the upper leaves are 1-2-pinnatisect, smaller and sessile (lacking a leaf stalk). Flowers: The tiny flower heads (capitula) are globose, 2-2.5 mm in diameter and borne in loose ...
China Kingherbs′ 99% Artemisinin (CAS No.: 63968-64-9), Find details about China Artemisia Annua Extract, Artemisinin from Kingherbs′ 99% Artemisinin (CAS No.: 63968-64-9) - Kingherbs Limited
Contents Home Artemisias in Cultivation Artemisia Drug Use Artemisia annua and research into Malaria therapy Artemisia annua Artemisia annua is a...
17 health benefits of Artemisia Annua that can prevent and cure diseases which are dangerous to the body and can increase beauty alongside appetite.
The medicinal plant Artemisia annua is the primary source of the leading antimalarial, artemisinin. However the yield of the drug is very low making it expensive and unprofitable to produce.. Our academic founder CNAP, increased the yield of artemisinin by applying a treatment that increases genetic diversity to A. annua seed. Using high-throughput genetic and phenotypic tests to select individual plants with increased levels of the drug, they developed genetic markers to fast-track breed high-yield hybrids.. The new varieties will be supplied for cultivation in Africa, India and China helping malarial nations contribute to their own national health issues.. ...
NutriCology Artemisinin 100mg 90 Capsules Pure artemisinin or Qinghaosu, the active constituent of the herb Artemisia annua (sweet wormwood). Good quality Artemisia annua contains 0.3-0.5% artemisinin, so pure artemisinin provides hundreds of times more of the active constituent artemisinin than the whole herb itself. NutriCology introduced artemisinin to the U.S. market more than a decade ago. NutriCology does independent potency assays on every batch (using HPLC), and independent tests verify its effectiveness. NutriCology artemisinin is minimum 98.5% pure, and does not contain thujone. For more information about quality of artemisinin, see High Quality Artemisinin. Suggested use: As a dietary supplement, 1 or 2 capsules one or two times daily before meals, or as directed by a healthcare practitioner. Artemisinin is best taken as part of a program that includes appropriate liver support nutrients. Sensitive individuals may want to take with food. CAUTION: Not indicated for pregnant or
Researchers at the University of Washington have updated a traditional Chinese medicine to create a compound that is more than 1,200 times more specific in killing certain kinds of cancer cells than currently available drugs, heralding the possibility of a more effective chemotherapy drug with minimal side effects.. The new compound puts a novel twist on the common anti-malarial drug artemisinin, which is derived from the sweet wormwood plant (Artemisia annua L). Sweet wormwood has been used in herbal Chinese medicine for at least 2,000 years, and is eaten in salads in some Asian countries.. The scientists attached a chemical homing device to artemisinin that targets the drug selectively to cancer cells, sparing healthy cells. The results were published online Oct. 5 in the journal Cancer Letters.. "The compound is like a special agent planting a bomb inside the cell," said Tomikazu Sasaki, chemistry professor at UW and senior author of the study.. In the study, the UW researchers tested their ...
Artemisinin the sesquiterpene endoperoxide lactone extracted from the herb Artemisia annua, remains the basis for the current preferred treatment against the malaria parasite Plasmodium falciparum. In addition, artemisinin and its derivatives show additional anti-parasite, anti-cancer, and anti-viral properties. Widespread use of this valuable secondary metabolite has been hampered by low production in vivo and high cost of chemical synthesis in vitro. Novel production methods are required to accommodate the ever-growing need for this important drug. Past work has focused on increasing production through traditional breeding approaches, with limited success, and on engineering cultured plants for high production in bioreactors. New research is focusing on heterologous expression systems for this unique biochemical pathway. Recently discovered genes, including a cytochrome P450 and its associated reductase, have been shown to catalyze multiple steps in the biochemical pathway leading to ...
Quicksilver Scientific liposomal Artemisinin , also known as Qinghaosu, is a compound isolated from plant Artemisia annua (sweet wormwood) that has been used by ...
Introduction: Artesunate is a semi-synthetic derivative of artemisinin, a natural compound from the herb sweet wormwood (Artemisia annua L). Artemisinin has been used for centuries in traditional Chinese medicine while artesunate has recently been used as an anti-malarial drug. Artesunate is also cytotoxic to human cancer cells. Since the use of artesunate as an anti-malarial agent is associated with few adverse effects, artesunate may represent a less toxic alternative to conventional chemotherapy. This study investigates the effects of artesunate on ovarian cancer cell lines and the mechanism(s) underlying its activity. Methods and Results: Artesunate had a time- and dose-dependent growth inhibitory effect on all ovarian carcinoma cell lines examined (SKOV3, OVCAR3, IG-OV-1, HEY) using an MTT assay. Further examination of artesunate-treated SKOV3 and HEY cells using Oregon Green-488 and Annexin-V-FLUOS/propidium iodide staining indicated that artesunate had a strong anti-proliferative effect ...
I totally agree with you, anyone can grow this, I planted it not knowing what it was, it never got watered and survived through -3c to 47c. I live in a very hot part of Western Australia and have done very little to help this plant along, it is vibrant and growing beautifully. Now that I know what it is I drink it daily and bathe my ponies cancerous eye in it daily. My pony is 28 years and the vet said I have no other option than to put her down because her tumour was quite nasty. I started to bathe her eye with a Artimisinin tea I brew, one day it bled a lot of muck/blood, since then it seems to be getting smaller and she comes to me and rubs her eye into it knowing its doing her good. I couldnt handle the taste/smell at first but now it just smells like disinfectant to me ...
Sigma-Aldrich offers abstracts and full-text articles by [Pamela J Weathers, Mostafa A Elfawal, Melissa J Towler, George K Acquaah-Mensah, Stephen M Rich].
Iron accumulates in cancerous cells due to special receptors that help them in cell division, called transferrin receptors. Normal cells likely have these receptors as well, but cancerous cells have them in greater abundance, and thus can be targeted by the iron-artemisinin combination, like a 1-2 punch.. There have been many experiments now that prove this sweet wormwood derivative can effectively eradicate disease in the presence of iron. The extract has been used for thousand of years in China to treat malaria. The malaria parasite cannot live in the presence of artemisinin because they are iron-rich, but the treatment works just as well for cancerous cells, too. Bioengineers Henry Lai and Narendra Singh of the University of Washington, Seattle were the scientists who initially made this discovery. This is yet another example of a natural herb causing cancerous cell apoptosis.. While the sweet wormwood extract has been somewhat difficult to obtain for a fair price for countless years, it is ...
Surgical Management of Hearing Loss Andrew McCall, M.D. FACS Assistant Professor Division of Otology and Neurotology Department of Otolaryngology University of Pittsburgh Medical Center None Disclosures
Tuesday, January 27, 2015. Ground-up artemisia plants, from which the anti-malaria drug artemisininis derived, appear to work much better than the refined drug does by itself, according to research at the University of Massachusetts.. Artemisinin, discovered by Chinese scientists in a project started by Mao Zedong to help the North Vietnamese, has become the newest malaria miracle cure. But parasites resistant to it have emerged.. Scientists infected mice with two strains of rodent malaria - one that is already artemisinin-resistant and one that is not, but is biologically similar to Plasmodium falciparum, the deadliest strain of human malaria. They then fed the mice pure artemisinin or dried artemisia annua plants bred for high drug content at Worcester Polytechnic Institute.. The study was published this month by the Proceedings of the National Academy of Sciences.. The whole plant cured mice with artemisinin-resistant malaria. In mice with the dangerous strain, parasites resistant to the ...
article{76337ac6-36e6-4fff-b6e8-dfb8093c0fd5, abstract = {A clone encoding farnesyl diphosphate synthase (FPPS) was obtained by PCR from a cDNA library made from young leaves of Artemisia annua. A cDNA clone encoding the tobacco epi-aristolochene synthase (eAS) was kindly supplied by J. Chappell (University of Kentucky, Lexington, KY, USA). Two fusions were constructed, i.e. FPPS/eAS and eAS/FPPS. The stop codon of the N-terminal enzyme was removed and replaced by a short peptide (Gly-Ser-Gly) to introduce a linker between the two ORFs. These two fusions and the two single cDNA clones were separately introduced into a bacterial expression vector (pET32). Escherichia coli was transformed with the expression vectors and enzymatically active soluble proteins were obtained after induction with isopropyl thio-beta-d-thiogalactoside. The recombinant enzymes were purified using immobilized metal affinity chromatography on Co2+ columns. The fusion enzymes produced epi-aristolochene from isopentenyl ...
Malaria brings misery and death to millions in the developing world each year, and the cycle of resistance to anti-malarial drugs is one of the great health problems facing the world today. UMass Amherst molecular parasitologist Stephen Rich and colleagues report a promising new low-cost combined therapy with a much higher chance of outwitting Plasmodium falciparum, the mosquito-borne parasite that causes the deadliest form of the disease. The results, if they translate to humans with further research, could drastically reduce the high cost associated with malaria treatment by allowing for low cost, locally sustainable production of whole plant therapy. The image above shows a detail of the plant used (Artemisia annua) and a microscopic image of red blood cells, some of which are infected with malaria parasites (those with purple/pink staining). Learn more.. Photo credit: Stephen Rich Research Group. ...
BBa_K1060002 contains an open reading frame that codes for a sesquiterpene synthase (GenBank Accession No. AY835398), (E)-b-farnesene synthase, that has been isolated from Artemisia annua (Picaud et al., 2005). The enzyme converts farnesyl diphosphate into E-β-farnesene. E-β-farnesene is an alarm hormone produced by aphids. It is also an important semiochemical in aphid localization. It is released in the cornicle secretions of many aphid species (Franscis et al., 2005) to alert surrounding aphids of the presence of natural enemies (Kunert et al., 2005). Detection of these short range chemical cues leads not to the aphid directly, but only indicates the presence, improving prey detection of the predators and parasitoids ...
http://allafrica.com/stories/200710150153.html 14 October 2007 Posted to the web 15 October 2007 Kampala The Youth in Kabale district are abusing Artemisia annua, a plant used for making...
From The Oregonian, Nov 28, 2001 p C12 Researchers find cancer hope in wormwood An herb mentioned in ancient Chinese texts helps fight malaria and kills cancer cells in the lab By RICHARD L. HILL, The Oregonian An ancient Chinese folk medicine thats effective against malaria also might be a potent cancer-fighting candidate, scientists at the University of Washington say. Henry Lai and Narendra Singh, research professors in UWs bioengineering department, have found that a compound - artemisinin - in a plant called sweet wormwood kills breast-cancer cells in the laboratory. Lai and Singh report in the current issue of Life Sciences that the chemical killed three-quarters of breast-cancer cells in eight hours and all of them in 16 hours. The compound appears to be extremely toxic to cancer cells but had little impact on normal cells, said Lai, who also has found the chemical to be effective in killing leukemia cells. In addition, its been shown to be safe because about 1 or 2 million malaria ...
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The striking simplification of artemisinin synthesis required not only a keen sense for an elegant combination of the correct partial reactions to enable the process to take place in a single step; it also took a degree of courage, as the chemists departed from the paths typically taken by industry up to now. The effect of the molecule, which not only targets malaria but possibly also other infections and even breast cancer, is due to, among other things, a very reactive chemical group formed by two neighbouring oxygen atoms - which chemists refer to as an endoperoxide. Peter Seeberger and François Lévesque use photochemistry to incorporate this structural element into the artemisinic acid. Ultraviolet light converts oxygen into a form that can react with molecules to form peroxides. 800 photoreactors should suffice to cover the global requirement for artemisinin. "Photochemistry is a simple and cost-effective method. However, the pharmaceutical industry has not used it to date because it was ...
There have been many experiments now that prove this sweet wormwood derivative can effectively eradicate disease in the presence of iron. The extract has been used for thousand of years in China to treat malaria. The malaria parasite cannot live in the presence of artemisinin because they are iron-rich, but the treatment works just as well for cancerous cells, too. Bioengineers Henry Lai and Narendra Singh of the University of Washington, Seattle were the scientists who initially made this discovery. This is yet another example of a natural herb causing cancerous cell apoptosis ...
Simon Best, Johns Hopkins University School of Medicine Discussion of different drugs and compounds that have been used in RRP or are under investigation Evaluation of evidence for and against the use of various adjuvant treatments in RRP and future directions in RRP research Cidofovir - Based on Hopkins study involving 162 patients (15 JORRP), it has shown efficacy but should be used cautiously as it may produce significant vocal fold scarring with some risk of nephrotoxicity. The Hopkins study does not indicate a significant dysplasia risk. DIM - P450 inhibitor that affects the metabolism of estrogen. Rosen et al., phase 1 study - 35 patients, 1/3, 1/3, 1/3 complete, partial, no response. According to the RRPF website, DIM is the most common adjuvant therapy among RRP patients with 55% overall positive response rate. Artemisinin - An herbal medicine also known as sweet wormwood that is widely used to treat Malaria. It has been used to treat some cancers by "starving" cancer cells of iron, ...
Allergy Research Group Tricycline is an herbal formula that features berberine (the active constituent of goldenseal), artemisinin (the active constituent of sweet wormwood), ...
Yeast make ACT production faster and more manageable. The microbes are not affected by weather, and they churn out artemisinic acid that is readily turned into semi-synthetic artemisinin, which Sanofi or other makers can convert into ACT ingredients such as artesunate. The whole process takes less than three months.
Also called honesty plant. I saw these purple wildflowers on the side of a road in April, not on someones property but on city property. They looked like some kind of tall roadside weed, so I didnt think it was so wrong to pick just two flowers. I stuck them in dirt and they are now quite happy. Ugly but happy. Ill plant them in my wildflower garden, near the back. I read that they are one of those dreaded and dreadful biennials. Bloom twice and then die. Ive come to dislike the whole idea of biennials. Seems unnatural. Plants should bloom always or once. Not some wishy washy middle ground. The top photo is from www.zum.de/stueber/lindman/212.jpg ...
The New York Flora Atlas is a source of information for the distribution of plants within the state, as well as information on plant habitats, associated ecological communities, and taxonomy. In addition, users can learn about the location of vouchered specimens and see images to get a better visual for each plant.
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A derivative of the sweet wormwood plant used since ancient times to fight malaria and shown to precisely target and kill cancer cells may someday aid in stopping breast cancer before it gets a toehold, according to a study by two University of Washington bioengineers.
Life is not what it used to be. Synthetic is an anthropological story about how it got that way. Living things bearing genomes streamlined or cobbled together from synthesized DNA now scurry, swim, and flourish in test tubes and bioreactors: viruses named for computer software, bacteria encoding passages of James Joyce, yeast buckling under the metabolic strain of genes harvested from sweet wormwood, petunias, and microbes from Icelandic thermal pools. This ... Read more. ...
What is the general view of the term and phenomena of penetrance? This refers to differential expression of a phenotype under various environmental conditions or genetic backgrounds, although the genotype of a plant or line is the same. It seems to be a rather vague term. My question arises because I may be seeing differing penetrance of flowering genes in Poa annua due to environment and genetic background. PJ john0130 at gold.tc.umn.edu ...
Artemisinin is an anti-malarial parasite drug extracted from a Chinese medicinal plant called sweet wormwood (Artemisia annua; Asteraceae family). It is also known as qinghaosu in Chinese and it is the most rapid acting drug currently available against the malarial parasite, Plasmodium falciparum.. The 2015 Nobel Prize in Physiology and Medicine is shared by William C. Campbell, Satoshi Omura and Youyou Tu for the discoveries of therapies against parasitic infections which saved millions of life over the globe. Among the three Nobel laureates, Professor Youyou Tu of China shares half of the Prize money for the credit of isolation, purification and structure elucidation of Artemisinin, the anti-malarial parasite drug for the first time from a Chinese traditional medicinal plant Artemisia annua. Professor Tu is the first China based Woman scientist to win the science Nobel.. Continue reading→. ...
International Scholarly Research Notices is a peer-reviewed, Open Access journal covering a wide range of subjects in science, technology, and medicine. The journals Editorial Board as well as its Table of Contents are divided into 108 subject areas that are covered within the journals scope.
Three native Turkish medicinal and aromatic plants (Artemisia absinthum, Artemisia santonicum and Saponaria officinalis) were investigated to analyze their antioxidant activity, total phenolic content and antimicrobial activity. Their total antioxidant activity was determined by using a β-carotene bleaching assay and their antimicrobial activity was determined by utilizing an agar disc diffusion assay. Methanol extracts of the three species analyzed showed high antioxidant activity and among them Artemisia absinthum possessed the highest quantity (71.78%). The total phenolic content (Folin-Ciocalteu assay) was shown to be between 6.57 µgGAE/mg dry weight basis (Saponaria officinalis) and 8.86 µgGAE/mg dry weight basis (Artemisia absinthum). There was a positive correlation (R = 0.819) between the total phenolic content and the antioxidant activity measured in the plant samples. The aqueous and methanol extracts of the aerial parts of the species showed antibacterial activities against a number of
Yet another list of one of their favorite natural remedies for acid reflux disease-like plant called Artemisia asiatica.. GERD/Acid Reflux and Natural Treatments. Artemisia asiatica and garlic have compounds which optimize bowel flora and kill this pathogenic organism.. Extraction and purification of eupatilin from Artemisia princeps. - Abstract−A recycling preparative HPLC was used to extract and separate the eupatilin contained in Artemisia princeps. PAMPAN, and the optimum operating. vious studies revealed that Artemisia asiatica, a medicinal plant that is widely used in traditional. TFA (trifluoroacetic acid) was from Sigma. (St Louis, MO, USA).. Home » Herbs for Gastroesophageal Reflux Disease. Artemisia asiatica. To assess three different methods of correlating symptoms with episodes of acid reflux.. Gaviscon® Neutralizes Stomach Acid And Helps Keep Acid Down for Hours!. Baby Acid Reflux Acid Reflux Gerd Gerd Surgery Pre Theyre Thanksgiving traditions for many, but so is unwanted ...
As a vassal of Persia, Artemisia was obliged to recruit her own small force when Xerxes invaded Greece - in fact, Artemisia commanded five ships in her own right. Artemisia alone of his commanders advised Xerxes against a naval battle with the Greeks but Xerxes, however, chose to follow the advice of his male advisors, and met the Greeks on the sea in the channel of Salamis on 20th September 480 BCE. Artemisia was aboard one of her ships, commanding their movements. After the initial confusion, the Persians took the offensive. Though she only had one ship left, Artemisia herself disabled the ship of King Damasithymus of Calynda. At a council, Artmesia spoke her mind - she had opposed the war from the beginning and opposed its continuation. She advised Xerxes to leave his trusted commander Mardonus to pursue the Greeks whilst Xerxes himself return home, and would still maintained his dignity whether in victory or defeat. For her wisdom, Xerxes entrusted Artemisia with the care on his sons, and ...
The NCBI web site requires JavaScript to function. Traditional Chinese Medicines TCM Artemisia bei Psoriasis rapidly gaining attention in the West as sources of new drugs, dietary supplements and functional foods.. However, Artemisia bei Psoriasis of consistent manufacturing practices and quality standards, fear of adulteration, and perceived deficiencies in scientific see more of efficacy and Artemisia bei Psoriasis impede worldwide acceptance of TCM. In addition, Western pharmaceutical industries Psoriasis von Barbera Behandlung regulatory agencies are partial toward single ingredient drugs based on synthetic molecules, and skeptical of natural product mixtures.. This review concentrates on three examples of TCM-derived pharmaceuticals and functional foods that have, despite these usual obstacles, risen to wide acceptance in the West based on their remarkable performance in recent scientific investigations. Sweet wormwood Artemisia annuathe source of artemisinin, which is the currently ...
Background and objectives: Toxoplasma gondii affects almost one-third of people worldwide, causing disorders such as abortion or congenital disease in its intermediate hosts. This is while the current available medications are limited in terms of efficacy and side effects. Previous researches have shown Artemisia annua to be highly effective on this parasite. The aim of this study was to evaluate the antitoxoplasma effects of A. vulgaris. Methods: Anti toxoplasmosis activity was evaluated in vitro using different concentrations of A. vulgaris total extract and the petroleum ether, chloroform, ethyl acetate and n-butanol fractions. After 2 h of incubation, flow cytometry method was applied to determine the anti-parasitic activity. Phytochemical profiles of these extracts were developed by HPTLC. For the in vivo experiment, toxoplasmosis was induced by intradermal injection of the parasite tachyzoites into the rats. Average survival time of the rats treated with 16-128 mg/kg of the total extract was
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The medicinal properties of the wormwood The discovery of the therapeutic benefits of the wormwood, once called ponema by the Gauls, is not new. This herbaceous plant is renowned for its strengthening power. It is also an excellent stimulant digestive, antispasmodic, anti-inflammatory, diuretic, antifungal and a powerful antibacterial. History of the use of wormwood in phytotherapy Scientific name: Artemisia vulgaris Botanical description of the wormwood
Artemisia from Allergy Research Group delivers a concentrated extract of the leaves of sweet wormwood, an herb that has been used for centuries in China. Each serving delivers...
Allergy Research Groups Artemisia provides sweet wormwood extract, which may offer natural support for healthy digestion. PureFormulas ships for free.
Wormwood Tales are stories written by the Wormwood creative team, designed to tell stories before, after and around our central tale. These stories may contain
Looking for Grande Wormwood? Find out information about Grande Wormwood. an emerald-green liqueur liqueur , strong alcoholic beverage made of almost neutral spirits, flavored with herb mixtures, fruits, or other materials, and... Explanation of Grande Wormwood
Mercurialis annua is a ANNUAL growing to 0.5 m (1ft 8in). It is not frost tender. It is in flower from Jul to October. The flowers are dioecious (individual flowers are either male or female, but only one sex is to be found on any one plant so both male and female plants must be grown if seed is required) and are pollinated by Bees, flies, wind.The plant is not self-fertile. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. Suitable pH: acid, neutral and basic (alkaline) soils. It cannot grow in the shade. It prefers moist soil.
Polyploidy is a key factor in the evolution of higher plants and plays an important role in the variation of plant genomes, leading to speciation in some cases. During polyploidisation, different balancing processes take place at the genomic level that can promote variation in nuclear DNA content. We estimated genome size using flow cytometry in 84 populations of 67 Artemisia species and one population of Crossostephium chinense. A total of 73 sequences of nrDNA ITS and 3′-ETS were newly generated and analysed, together with previously published sequences, to address the evolution of genome size in a phylogenetic framework. Differences in 2C values were detected among some lineages, as well as an increase of genome size heterogeneity in subgenera whose phylogenetic relationships are still unclear. We confirmed that the increase in 2C values in Artemisia polyploids was not proportional to ploidy level, but 1Cx genome size tended to decrease significantly when high ploidy levels were reached. ...
Botanical Name: Artemisia glacialis Family: Asteraceae Tribe: Anthemideae Genus: Artemisia Species:A. glacialis Kingdom:Plantae Order: Asterales Common Name :
APG IV Classification: Domain: Eukaryota • (unranked): Archaeplastida • Regnum: Plantae • Cladus: angiosperms • Cladus: eudicots • Cladus: core eudicots • Cladus: superasterids • Cladus: asterids • Cladus: euasterids II • Ordo: Asterales • Familia: Asteraceae • Subfamilia: Asteroideae • Tribus: Anthemideae • Genus: Artemisia • Species: Artemisia afra Jacq. ex Willd., 1804 ...
175. Artemisia angustissima Nakai, Bot. Mag. (Tokyo). 29: 8. 1915. 狭叶牡蒿 xia ye mu hao Artemisia japonica Thunberg subf. angustissima (Nakai) Pampanini; A. japonica var. angustissima (Nakai) Kitamura.. Herbs, perennial, 20-60 cm tall, stems few, slender and erect, branching from upper nodes, sparsely arachnoid pilose, ± glabrescent. Lower and middle stem leaves ± sessile; leaf blade ovate or suborbicular in outline, 1.5-2.2 × 1.5-2.2 cm, (1 or)2-pinnatisect; segments 2(or 3) pairs, 5-10 × 3-5 mm, partite or few serrate. Middle stem leaves pinnatisect; lobes linear or narrowly linear-lanceolate, 5-8(-10) × 0.8-3 mm, entire or few serrate. Uppermost leaves and leaflike bracts 3-sect or entire. Synflorescence a narrow panicle. Capitula shortly pedunculate or sessile, nodding. Involucre ovoid or subglobose, 1-1.5 mm in diam. Marginal female florets 2 or 3. Disk florets 2-5, male. Achenes obovoid. Fl. and fr. Aug-Oct.. Slopes, roadsides; low elevations to 500 m. S Gansu, Hebei, SE ...
In general as far as I know customers who bought Merrell Womens Artemisia Lace-Up or other products in the Internet also were interested in reviews, cheap & lowest prices in outlets and stores, shipping, gift ideas, city deals, sales, coupons online, new, holiday & daily deals, bargain, best buy products including special offers on Merrell Womens Artemisia Lace-Up, best deals, discount coupons, top & hot deals, great offers, last minute deals and so on ...
Artemisia stelleriana, also known as Artemisia Silver Brocade, grows in U.S. Department of Agriculture hardiness zones 3 through 9. Silver Brocade closely resembles an annual bedding plant ...
The report generally describes artemisia baumgarteni, ext., examines its uses, production methods, patents. Artemisia baumgarteni, ext. market situation
Artemisia stelleriana Moris Form is good for ground cover planted under an Abraham Darby rose bush to contrast the grey and soft yellow. Buy Artemisia stelleriana Moris Form
Yin Chen Hao is also known as Capillaris. The acrid, bitter and cool herb has been used in TCM asantipyretic agent and to treat liver infection of liver and gallbladder, jaundice, difficulty in urination headaches, etc., as it clears Heat and Damp-Heat, drains Heat and damp-Heat, etc., by enhancing the functions of liver, spleen, gallbladder …. ...
Wormwood oil is considered as a narcotic oil when used in higher doses. The adverse effects of Wormwood oil is attributed to the presence of chemical constituent thujone, which contributes to about 50 percent of the oil. Thujone containing oils are restricted prevalently, mainly due to the concern of its psychotropic, nephrotoxic and neurotoxic effects. It may cause skin irritation, redness, eruptions in sensitive skin and dermatitis.. Studies witness the excitation of the autonomic nervous system due to convulsions and binding of the GABA receptors caused due to α and β-thujone. It is also a known fact that high amount of thujone and its metabolites can induce convulsions, unconsciousness, seizures, gastrointestinal cramps, insomnia, tremors, dizziness, hallucinations, vomiting, headaches, retention of urine, renal lesions, congestive heart failure and rhabdomyolysis (collapse of muscular fibers).. Wormwood should never be used internally as there are numerous studies witnessing the severe ...
Alibaba.com offers 1,361 wormwood herb products. About 42% of these are herbal extract, 11% are equipments of traditional chinese medicine, and 4% are crude medicine. A wide variety of wormwood herb options are available to you, such as free samples, paid samples.
Artemisia absinthium plant What is wormwood? A drawing of warmwood Common name in English: Wormwood, holy grass, assensio, bitter sagebrush, ajorizo. Common name in other languages: - Spanish /Español: Ajenjo, hierba santa, asensio, artemisa amarga, ajorizo. - Catalan / Català: donzell
Incorporating the use of glyphosate into a weed management program offers turfgrass managers increased flexibility and cost savings when attempting to control troublesome weeds such as annual bluegrass (ABG) (Poa annua L.). Field trials of glyphosate tolerant perennial ryegrass (PRG) (Lolium perenne L.) cultivars, JS501 and Replay, were initiated to determine glyphosate tolerance and rates required for ABG control. In the tolerance trial, glyphosate was applied on 15 Sept. 2010 and 9 Aug. 2011 at rates of 0, 0.29, 0.58, 1.16, 1.74, 2.32, and 3.48 kg.ha-1 a.e. Glufosinate was also applied at 0, 1.68, and 3.37 kg.ha-1 a.i. In the ABG control trial, glyphosate was applied on 17 June followed by 19 Aug. 2009 and 25 June followed by 25 Aug. 2010 at rates of 0, 0.15, 0.29, 0.44, and 0.58 kg.ha-1 a.e. In the tolerance trial, linear regression analysis revealed a glyphosate application rate of 0.81 kg.ha-1 a.e. was required to cause 20% leaf firing. By the end of the trial, the highest rate of ...
Incorporating the use of glyphosate into a weed management program offers turfgrass managers increased flexibility and cost savings when attempting to control troublesome weeds such as annual bluegrass (ABG) (Poa annua L.). Field trials of glyphosate tolerant perennial ryegrass (PRG) (Lolium perenne L.) cultivars, JS501 and Replay, were initiated to determine glyphosate tolerance and rates required for ABG control. In the tolerance trial, glyphosate was applied on 15 Sept. 2010 and 9 Aug. 2011 at rates of 0, 0.29, 0.58, 1.16, 1.74, 2.32, and 3.48 kg.ha-1 a.e. Glufosinate was also applied at 0, 1.68, and 3.37 kg.ha-1 a.i. In the ABG control trial, glyphosate was applied on 17 June followed by 19 Aug. 2009 and 25 June followed by 25 Aug. 2010 at rates of 0, 0.15, 0.29, 0.44, and 0.58 kg.ha-1 a.e. In the tolerance trial, linear regression analysis revealed a glyphosate application rate of 0.81 kg.ha-1 a.e. was required to cause 20% leaf firing. By the end of the trial, the highest rate of ...
113. Artemisia mattfeldii Pampanini, Nuovo Giorn. Bot. Ital., n.s.,. 36: 425. 1930. 粘毛蒿 nian mao hao Herbs, perennial, 35-50 cm tall, capitately branched, densely glandular pubescent, strongly aromatic. Lowermost and middle stem leaves: petiole 2-3 cm or more; leaf blade oblong or oblong-ovate, 3.5-6 × 1.5-4 cm, abaxially gray or yellowish arachnoid tomentose or glabrous, adaxially and abaxially on veins glandular pubescent. Lowermost leaves (2 or)3-pinnatisect; middle leaves 2(or 3)-pinnatisect; segments 5 or 6 pairs, ovate or oblong-ovate, 1.5-2.5 × 1-1.5 cm; lobules lanceolate or deeply serrate, 3-7 × 1-1.5 mm, margin revolute, acute or obtuse apically; rachis winged. Uppermost leaves and leaflike bracts 1- or 2-pinnatisect. Synflorescence a narrow panicle. Involucre oblong or broadly ovoid, 3-4 mm in diam.; phyllaries sparsely glandular pubescent. Marginal female florets 5-7. Disk florets 8-15, bisexual. Achene obovoid or oblong. Fl. and fr. Jul-Oct.. ● Forest margins, grasslands, ...
Artemisia vulgaris (Ai Ye) has a long and rich history of use in medicine as an herbal remedy. This page contains uses, pictures, cautions, and references.
|i|Artemisia|/i| is an important genus of Iranian flora. Cytotoxic activities for some species of the genus have already been reported. In this study, we have investigated the cytotoxic effects of |i|n|/i|-hexane, CH|sub|2|/sub|Cl|sub|2|/sub|, EtOAc, EtOH, and EtOH/H|sub|2|/sub|O (1 : 1) extracts of |i|A. turanica|/i| Krasch. on two human leukemic cancer cell lines (K562 and HL-60) and J774 as normal cells using alamarBlue (resazurin) assay. PI staining of the fragmented DNA and western blot analysis were used to evaluate the possible apoptotic effect of the extract. The CH|sub|2|/sub|Cl|sub|2|/sub| extract of |i|A. turanica|/i| showed the most antiproliferative effect on cancer cells among all tested extracts with IC|sub|50|/sub| values of 69 and 104 |i|μ|/i|g/mL on K562 and HL-60 cells, respectively, whereas the normal cells were not affected significantly by this extract. Sub-G1 peak in the flow cytometry histogram of the cells treated with CH|sub|2|/sub|Cl|sub|2|/sub|
It is also effective against bladder infections and helps the liver and bile process waste. Treatments for the stomach, gall bladder and spleen work more effectively when they contain elements of the Artemisia plant.. For external treatment of wounds and insect bits, the herb is most commonly administered in decoctions and infusions.. For internal use, extracts and herbal tinctures, as well as capsules with powdered or solid herb can be taken. In fact, due to the bitter taste, it is often easiest to ingest the herb in capsule form.. ...
Discover Lifes page about the biology, natural history, ecology, identification and distribution of Artemisia ludoviciana image
Shop artemisia gentileschi metal prints from thousands of artists from around the world. Our metal wall art produces vibrant colors and amazing details. Worldwide shipping available at Society6.com.
Dark Progressive metallers Sun Caged are back with Artemisia, their second album - but is it really Sun Caged? A new vocalist, keyboardist, drummer and bassist have joined the ranks since the release of their last album in 2003 leaving only one founding member. Nonetheless, these guys have really found their groove and perform on this album like theyve been writing and playing music together for a long time ...
SYNOPSIS: Italy, 1610. Artemisia (Valentina Cervi) is seventeen years old and has inherited her well-known painter-father Orazio s (Michel Serrault) talent and passion for painting. But painting is forbidden for
The aqueous extract of Artemisia herba-alba Asso. (Compositae) produced an initial hyperglycaemia which was followed by hypoglycaemia in normoglycaemic and alloxan-treated rabbits and mice. The extract (0.39 g/kg) significantly increased gastrointestinal transit time and the reaction time to thermal stimuli but had no effect on the activity of alkaline phosphatase or concentrations of creatinine and urea in plasma. Histopathological examination indicated mild hydropic degeneration in hepatocytes and proximal convoluted tubules. The duodenum showed mild oedema of the substantia of the mucosal propria. The plant extract showed weak antimicrobial activity.
Rodrigo Santoro, wholl reprise his role as Xerxes, says director Noam Murros |i|300: Battle of Artemisia|/i| begins filming in July, and confirms the spin-off depicts the series of naval engagements that occurred at the same time as the Battle of Thermopylae.
... - Paintings Index - Artchive.com - Galleries of famous artists - old masters & contemporary. Words largest virtual museum. Featuring the largest collection of paintings by artists like Renoir, Da Vinci, Picasso and more
One of the lesser known herbs, or rather underutilized in some regions, is the southernwood herb plant, also known as southernwood Artemisia. Learn more about this plant is the article that follows.
title: DA-9601, Artemisia Asiatica Herbal Extract, Ameliorates Airway Inflammation of Allergic Asthma in Mice, doi: none, category: Article
Wormwood 365mg (100 capsules). Ingredients: Wormwood (Artremesia absinthinum) 365 mg, gelatin capsule. Suggested Use: Adults and children 12 or more years of age: 1-3 capsules daily or as directed. For further information, please view the product label by clicking the blue
Dr. Baker responded: NO!!!. Most herbal medicines are quite safe but wormwood is not one of them! there are several varieties of wormwood, but this usually refers to artemesia absinthium. It has a long history of folk use for treating worms, dyspepsia & |a href="/topics/fever" track_data="{
Aromatic and bitter perennial plant form compositae family up to 90 cm.. Erect stems, woody below, whitish and pubescent, ribbed, arising from a perennial underground rhizome.. Leaves with silky hairs on both sides which provides a soft touch. Lower leaves with long petioles up to 25 cm long, pinnate or tripinnade; higher with shorter petioles, sometimes without petiole, with the vertices of leaflets obtuse, what mainly differentiates this species from Artemisia vulgaris, presenting more pointed ends.. Yellow flowers gathered in deciduous inflorescences almost globular (heads) of 3 to 5 cm in diameter, composed of many tubular florets. The heads are arranged along panicles, attached to the stem by long petioles, with a bract at their base that reminds the rest of the leaves. Pendulous heads with silky hemispherical cup is what mainly distinguishes this species from other plants of the genus Artemisia.. Fruits in aqueny. It blooms from July to September.. ...
PYTF0078 King Toad China, Our factory specialize in manufacture and process of Argy wormwood leaf and relative products , with annual production capacity of 1200MT, it is mainly exported to Japan,
There does not appear to be any scientific evidence supporting the claim that wormwood tea can treat parasitic infections. NYU Langone Medical Center admits there are extremely preliminary...
My son takes this product together with a liquid chlorophyll. We think that to take chlorophyll with this Wormwood Compination is more healthy and you can be sure that all toxins were removed from the body. My son doesnt notice yet any worms running like a lamplighter from his body but he believes that it is necessary to take a worm killing product twice a year (in spring and in fall) in order to be cleansed from the uninvited tenants. If my review was helpful to you, please click YES below. Thanks!-------- Мой сын принимает этот продукт вместе с жидким хлорофиллом. Мы считаем, что этот продукт стоить принимать вместе с хлорофиллом, так как это полезно для здоровья, и для того, чтобы быть уверенным, что все токсины выведены из организма. Мой сын пока не заметил паразитов, ...
Wormwood is sometimes recommended today for the treatment of digestive conditions such as intestinal parasites, dyspepsia, esophageal reflux, and irritable bowel syndrome. However, there is no meaningful evidence to indicate that it is effective for any of these conditions. Only double-blind, placebo-controlled studies can show a treatment effective, and only one has been performed using wormwood. (For information on why such studies are essential, see Why Does This Database Rely on Double-blind Studies?) This 10 week study conducted in Germany evaluated the potential benefits of wormwood for treatment of people with Crohns disease, an inflammatory condition of the intestines.9 All forty people enrolled in the study had achieved good control of their symptoms through use of steroids and other medications. Half were given an herbal blend containing wormwood (500 mg three time daily) while the other half were given an identical-appearing placebo. Both researchers and study participants were kept ...
Buy Wormwood 60 Capsules Online in Australia, Compare Prices of 100 Products from 5 Stores. Lowest Price is $9.09. Save with MyShopping.com.au!
I have not heard of Chronicles of Wormwood up until this part, but when you have Garth Ennis writing such a strange script...how can you resist. Look at th
M. Suchy, Z. Samek, V. Herout, R. B. Bates, G. Snatzke, and F. Sorm, Coll. Czech. Chem. Comm., 32, no. 11, 3917, 1967.Google Scholar ...
Malaria is a deadly disease. Because of its reliance on tropical mosquitos for transmission, it disproportionately affects people living in the developing world
AI XIN China, PURE MOXA-ROLL Exquisite moxa-roll is made of pure argyi powder. It is easy to light with fragrant odour which is no irritation to body. specification: Φ12×120mm hollow main ingredient:
This herbaceous perennial may not be so pronounced as its French counterpart but is it is a much more hardy plant that prefers poor soils and can cope with a bit of neglect. It produces lots of leaves, which can be used for a milder flavour. Tarragon will make its home in the poorest area of your garden. It prefers full sun and dry sandy soil. They are perfect for growing in containers near the kitchen door. To order this plant email: [email protected] ...
Agnelarul John Nayagam*, Shobana Gunasekaran, Santhi R. ABSTRACT. Epilepsy is the second most common neurologic disorder after stroke. Approximately 1% of the worlds population has epilepsy, is a condition where the people suffer from recurrent seizure. The present study was aimed to evaluate the antiepileptic activity of aqueous extract of Artemisia nilagrica Linn. On ethanol induced seizures in albino rats. Experiments were carried out in wistar strains of albino rats and rats were divided in five groups. Group I rats was treated as normal, Group II rats was administrated with ethanol (38/ 1g bw/ day) for 30 days, Group III and Group IV rats was administrated with ethanol (38/1gbw/day) and followed by aqueous extract of Artemisia nilagrica Linn (100 and 200mg/1g bw/day) for 30 days. The effect of ethanol in the brain was estimating the physical behaviors like Immobility and swimming test, nociceptive function, locomotors activity, lipid peroxide antioxidants (SOD, LPO, and GSH) and neuro ...
Available: http://www.calflora.org/ (Accessed: Dec 16, 2017). The information on this page comes from diverse sources. None of the links are sponsored. ...
Pareur: Orecchini + Girocollo + Bracciale + Anello in materiale argentato anallergico con rose e perline nere ***La spedizione avverrà col servizio Posta Prioritaria di Poste Italiane (pacco non ...
An article published in Dogs Naturally magazine in August of 2015 espoused the use of a natural plant compound called artemisinin in treating canine cancer. A researcher at the University of Washington, Dr. Henry Lai, treated a dog with severe osteosarcoma who could barely walk with the compound and five days later, the dog had made a complete recovery. X-rays indicated that the tumor was completely gone. When my first dog, Porter, was diagnosed with hemangiosarcoma, artemisinin was one of the ingredients in his supplements. But because his cancer had already metastasized, it is hard to say whether anything could have helped him by that point.. The effectiveness of artemisinin relies on the high iron concentrations and transferrin receptors that are found in cancer cells. When the compound comes into contact with iron, it causes a chemical reaction where free radicals are created from charged atoms that are released. The free radicals then "attack and bind with cell membranes, breaking them ...
New"fork AvertlMeU. OltNAMENTAL IRON WORK. , Wrought !aa ...... ...i.iKnx. O.TEWAr., WW. BALCON- ,.o FARM FBNUE8, TUI OUaW STALL QUABI. MA0B AMD WIN- DOW QUAED. f i . . " - - Ir.n rrHre. ..i.,... rtadu-. and CHI. AkwMetlniMS, ell J- -. . . ...-a. u. v ir riowr Train., , , i-t NU"U"""- BUW,HIBO.WIOiB.HAm DAILY OHIO STATE TTfnTr J TTD TT A 7T VOLUME XXVI COLUMBUS, OHIO.- Fill OA YJ MORN IN a, JULY 18, 1SU2, NUMBER 14." Cincinnati Adverflaelna. H P 15 K R H. ihhab, r . ii i II.:,:.. ci..: j No. ?A o.el etrew, er Broadway, ew , wr- it bBiVISI UIVWIVII nillllf) Hum no. aoauaaei air, ,7 ,1" .,el Agt foe "Mew Hoik WlfW-IUUim Oe, may lo-ano ud Blacking LiboraUrj. EARLES NEW HOTEL I No M WfUMl.g.,, Cincinnati, o i.... ,,Mae CHEMICAL WBITISO FLUID, Termts. $1.50 per Day. Illkfl A BO VK IIOTKl. IS OW OMI I f..r lh. ncntlonof itnaeta. The looetloa MIDI OH trel It very eoof enleut to buaineM and plaoM of annua. Oopyl.g, BI.C OIIi Bio., rtormtae, Jepa., Stenciling end POXiZH abb Feb-M-ly ...
My vase this week is very simple. A neighbor up the road has Silver Dollar Plant (Lunaria annua) that she tossed in the field next to the road many years ago, and it has self-sowed each year since. Every fall, if I pass that way before theyve fallen to the ground, I pick a bunch of the dried…
BACKGROU ND: U.S. professional medical societies and the national health systems of all other industrialized nations recommend that most women need not undergo Papanicolaou (Pap) smear screening annua
Bynke - Wikipedia, den frie encyklopædi.Bynke (Artemisia) er en slægt med ca. 85 arter, der er udbredt i Europa, Nordafrika, Asien og Nordamerika. Det er stauder, som har fjersnitdelte, duftende blade.--Have-Malurt - Wikipedia, den frie encyklopædi.Have-Malurt (Artemisia absinthium) er en op til 100 cm høj urt, der i Danmark vokser vildt på strandvolde og nær bebyggelse. Alle overjordiske dele af planten er ...--Estragon - Wikipedia, den frie encyklopædi.Estragon (Artemisia dracunculus) er en staude med en opret, svagt forgrenet vækst. Den bliver dyrket på grund af den karakteristiske, anisagtige duft fra bladene ...--Grå-Bynke - Wikipedia, den frie encyklopædi.Grå-Bynke (Artemisia vulgaris) er en 60-120 cm høj urt, der vokser langs veje og på agerjord. Beskrivelse. Grå-Bynke er en høj flerårig urt med en stift opret ...--Malurt - Wikipedia, den frie encyklopædi.Malurt har flere betydninger: Malurt er et dansk rockband. Forskellige plantearter af slægten Malurt (Artemisia), ...
A number of studies have been undertaken into the bioactive properties of the volatile oil from Artemisia dracunculus (). In two studies into insect responses to the volatile oil and its constituents, Papilio spp. evoked different reactions to the oil. Using GC coupled electroantennograms, they were able to demonstrate which components from the oil were active in determining oviposition preference and larval performance, areas where plant extracts could be used in insect control. In a further study, the attractiveness or repulsiveness of Artemisia dracunculus volatile oil towards insects infected with tick-borne encephalitis virus allowed not only those infected to be distinguished from those uninfected, but to identify individuals with varying degrees of virus replication.. The antimicrobial properties of various species of Artemisia are well recorded where a number of Gram positive and Gram negative bacteria were inhibited in their growth. The test bacteria are all capable of infection, and ...
Looking for online definition of Artemisia absinthium in the Medical Dictionary? Artemisia absinthium explanation free. What is Artemisia absinthium? Meaning of Artemisia absinthium medical term. What does Artemisia absinthium mean?
Since there has been an Absinthe revival in many countries over the past few years, many people are seeking Absinthe info.. Absinthe is known as "La Fee Verte" or "The Green Fairy" because of its characteristic green color. Different from the alcoholic beverages beer and cider it is distilled generally with a wine base and a variety of herbail ingredients.. Absinthe got its name and its distinctive bitter taste from the wormwood, artemisia absinthium. Some "fake" Absinthes do not contain wormwood because thujone, from wormwood, was strictly regulated in countries like the USA and proper wormwood Absinthe was banned.. Fennel, green aniseed, star anise, hyssop, lemon balm, juniper, angelica, licorice, dittany, coriander, nutmeg and sweet flag are the different types of herbs and essential oils used in Absinthe production. Due to the essential oils Absinthe louches when coming in contact with water. The oils are soluble in alcohol but not in water and so cause the drink to go cloudy.. Absinthe ...
Objective: To evaluate the effects of Salvia officinalis and Artemisia abrotanum extracts against digestive system parasites of mice. Methods: The ethanol extract was prepared and dissolved in distilled water. The mebendazole was used as positive control and distilled water as negative control. After counting eggs per gram feces, infected mice with 16 eggs per gram feces contained two to three parasites of Syphacia obvelata, Aspicoloris terepetra and Hymenolipis nana designated in 4 groups. The first group was given extracts of Artemisia (150 mg/kg), the second group was given Salvia extract (150 mg/kg), the third group was given mebendazole (10 mg/kg) and finally the fourth group was given distilled water (2 mL/kg). Results: The ethanol extracts of Artemisia and Salvia plants reduced the number of parasite eggs per gram of feces. Results showed significant reduction (P-value,0.001) in the number of eggs excreted by Hymenolepis nana, Aspiculuris tetraptera, Syphacia obvelata in mice. ...
Thirteen-week repeated dose toxicity study - posted in Absinthe In Science: Thirteen-week repeated dose toxicity study of wormwood (Artemisia absinthium) extract in rats.Muto T, Watanabe T, Okamura M, Moto M, Kashida Y, Mitsumori K.Laboratory of Veterinary Pathology, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo 183-8509, Japan.Wormwood, Artemisia absinthium, is a very bitter plant, and its extract has been used as food additives...
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Another issue, Crane Fly Larvae LOVE to chew on our chosen varieties and dont like the native grasses like Poa Trivialis, Poa Annua and Native Creeping Bentgrass. (see photos). Normally when our chosen varieties are growing well under normal weather conditions we can tolerate as many as 10-12 larvae per square foot. Since there is nothing "Normal" about this spring, the Crane Fly Larvae are causing more visible damage. We are always inspecting for Crane Fly Larvae. When damage is detected and an application is warranted, we will set up a Spring Curative Application for your lawn. Remember, to protect beneficial insects, microorganisms and earth worms, it is our environmental policy to ONLY apply insect control when it is required or requested to protect your turf! Insect control is not included in any of our programs and is billed at the time of service (BATS). It is also price to all prepaid program customers.. Thanks for reading! If all of you could please do your best "Sun Dance" maybe that ...

Correlation among agronomic, physiological and phytochemical traits in Artemisia annua L. varietiesCorrelation among agronomic, physiological and phytochemical traits in Artemisia annua L. varieties

Um estudo químico de Artemisia annua L. aclimatada no Brasil [A chemical study of Artemisia annua L. acclimatized in Brazil]. ... de Artemisia annua L. [Characterization of the photosynthetic mechanism and aspects related to the flowering of Artemisia annua ... Seleção, melhoramento e nutrição da Artemisia annua L., para cultivo em região intertropical [Selection, improvement and ... FERREIRA, J.F.S. Artemisia annua L.: The hope against malaria and cancer. Medicinal and aromatic plant: Production, business ...
more infohttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-05722013000100019&lng=en&nrm=iso&tlng=en

PatientsLikeMe | Artemisia Absinthium (wormwood) report for  patients like youPatientsLikeMe | Artemisia Absinthium (wormwood) report for patients like you

Find the most comprehensive real-world treatment information on Artemisia Absinthium (wormwood) at PatientsLikeMe. 4 patients ... bipolar I disorder or psoriasis currently take Artemisia Absinthium (wormwood). ... See also: Artemisia annua Wormwood is used primarily for liver, gall bladder and stomach ailments. It is also used to make a ... Stopped taking Artemisia Absinthium (wormwood) Duration. Patients. This item is relevant to you: Less than 1 month 1 * 1 ...
more infohttps://www.patientslikeme.com/treatments/show/9316-artemisinin-side-effects-and-efficacy

Artemisia annua - WiktionaryArtemisia annua - Wiktionary

species): Asteraceae - family; Asteroideae - subfamily; Anthemideae - tribe; Artemisiinae - subtribe; Artemisia - genus; ... Retrieved from "https://en.wiktionary.org/w/index.php?title=Artemisia_annua&oldid=48186633" ... Artemisia annua on Wikipedia.Wikipedia. *. Artemisia annua on Wikispecies.Wikispecies. *. Artemisia annua on Wikimedia Commons. ... Artemisia - subgenus; Artemisia sect. Seriphidium - section. References[edit]. *. ...
more infohttps://en.wiktionary.org/wiki/Artemisia_annua

Artemisia annua L.: a source of novel antimalarial drugs | SpringerLinkArtemisia annua L.: a source of novel antimalarial drugs | SpringerLink

Artemisia annuaL. contains artemisinin, an endoperoxide sesquiterpene lactone, mainly in its leaves and inflorescences. This ... Tissue culture ofArtemisia annua L.- a potential source of an antimalarial drug. Current Sci 1988;57:344-6.Google Scholar ... Rücker G, Mayer R, Manns D.α- Andβ-myrcene hydroperoxide fromArtemisia annua. J Nat Prod 1987;50:287-9.Google Scholar ... Artemisia annua L. Artemisinin Biosynthesis Chemistry, analytical Clinical trials Pharmacology Sesquiterpene lactones Structure ...
more infohttps://link.springer.com/article/10.1007%2FBF01980041

Artemisia annua leaf powder cures resistant malaria - ESCOPArtemisia annua leaf powder cures resistant malaria - ESCOP

Artemisia annua, considered a safe herb (GRAS), having been consumed by humans and traditionally used as a therapeutic remedy, ... Cultivating Artemisia annua and producing and testing the tablets, according to Weathers, are ideal local businesses that can ... It is a pioneer in the use of Artemisia annua leaf extract as a therapy against malaria. According to this researcher, this is ... In 2011 published his first study in Phytochemistry Reviews in which he showed that the leaf of Artemisia annua is able to ...
more infohttp://escop.com/herbal-treatment-cures-malaria-resistant-to-treatment/

Artemisia Annua - 1 fl. oz (30 ml)Artemisia Annua - 1 fl. oz (30 ml)

Artemisia Annua Extract by Herb Pharm provides sweet wormwood, which is an herb that may work to maintain digestive health. ... Never used Artemisia Annua by Herb Pharm before, I got it for my dog who has lymphoma and Artemisia Annua is a recommended ... Never used Artemisia Annua by Herb Pharm before, I got it for my dog who has lymphoma and Artemisia Annua is a recommended ... Artemisia Annua Flowering Herb (Artemisia annua) (O) Extract 652mg(E) / †. †Daily Value (DV) not established.. (O)Certified ...
more infohttps://pureformulas.com/artemisia-annua-1-oz-by-herb-pharm.html

FAEC - Artemisia annua tea: prophylaxis against malariaFAEC - Artemisia annua tea: prophylaxis against malaria

... promote artemisia annua tea in tropical countries. This plant has excellent therapeutical properties against malaria, as ... In 2010 artemisia annua plantations were extended to some 50 schools. Pupils and teachers use the tea as cure against malaria ( ... PE Ogwang et al., Brit J Pharm Res ISSN 2231-2919). A medical team at Luxembourg had already found in 2010 that Artemisia annua ... And over the months they noticed that Artemisia annua has a strong prophylactic effect. Absenteeism for students and teachers ...
more infohttp://www.mitosyfraudes.org/Pesti/prophylaxis.html

Isolation and characterization of AaAER, a novel double bond reductase from Artemisia annua | SpringerLinkIsolation and characterization of AaAER, a novel double bond reductase from Artemisia annua | SpringerLink

... gene from Artemisia annuaL. cDNA library through homologous cloning strategy. Enzymatic properties of AaAER, including ... Artemisia annua L Detoxification Double bond reductase Enzyme activity Reactive carbonyls Abbreviations. MeJA. Methyl jasmonate ... We isolated a 2-alkenal reductase (AaAER) gene from Artemisia annua L. cDNA library through homologous cloning strategy. ... Isolation and characterization of AaAER, a novel double bond reductase from Artemisia annua ...
more infohttps://link.springer.com/article/10.1007%2Fs13562-014-0278-2

Taxonomic Implications of Artemisia annua L. | Springer for Research & DevelopmentTaxonomic Implications of Artemisia annua L. | Springer for Research & Development

... belongs to genus Artemisia L. of family Asteraceae and tribe Anthemideae. ArtemisiaL. approximately comprises of about 500 taxa ... Artemisia annua L. (sweet sagewort) belongs to genus Artemisia L. of family Asteraceae and tribe Anthemideae. Artemisia L. ... Taxonomic Implications of Artemisia annua L.. In: Aftab T., Ferreira J., Khan M., Naeem M. (eds) Artemisia annua - Pharmacology ... Yang R-Y, Zeng X-M, Lu Y-Y et al (2009) Senescent leaves of Artemisia annua are one of the most active organs for ...
more infohttps://rd.springer.com/chapter/10.1007/978-3-642-41027-7_6

Sweet Annie, Sweet Sagewort, Annual Wormwood, Huang Hua Hao  Artemisia annuaSweet Annie, Sweet Sagewort, Annual Wormwood, Huang Hua Hao Artemisia annua

Artemisia annua) supplied by member gardeners in the PlantFiles database... ... the 2012 hot season and 2013 cold season to determine the most effective treatment for rapid germination of Artemisia annua by ... annua. Early March is recommended as the ideal planting period so that seedlings are transplanted on the field at the onset of ...
more infohttps://davesgarden.com/guides/pf/go/1140/

Artemisia annua - WikipediaArtemisia annua - Wikipedia

1753 Flora of Pakistan Altervista Flora Italiana, Assenzio annuale Artemisia annua L. Anonymus. "Artemisia annua (sweet ... for Artemisia annua L. Simonnet, X.; Quennoz, M.; Carlen, C. (2006). "New Artemisia annua hybrids with high artemisinin content ... Dry leave yields of Artemisia annua plantations vary between 0.5 and 3 t/ha. Source: In terms of the climate A. annua prefers ... armoise annuelle Artemisia annua Linnaeus, Sp. Pl. 2: 847. 1753. Flora of China Vol. 20-21 Page 691 黄花蒿 huang hua hao Artemisia ...
more infohttps://en.wikipedia.org/wiki/Artemisia_annua

Frontiers | Leishmanicidal activities of Artemisia annua leaf essential oil against Visceral Leishmaniasis | MicrobiologyFrontiers | Leishmanicidal activities of Artemisia annua leaf essential oil against Visceral Leishmaniasis | Microbiology

In this study, we showed the leishmanicidal effect of essential oil from Artemisia annua leaves (AALEO) against Leishmania ... In this study, we showed the leishmanicidal effect of essential oil from Artemisia annua leaves (AALEO) against Leishmania ... FIGURE 5. Artemisia annua leaves induces cell cycle arrest in L. donovani promastigotes at sub-G0-G1 phase. After treatment ... Artemisia annua leaves (0-100 μg ml-1) treatment demonstrated a dose-dependent killing of the promastigotes and a 50% ...
more infohttps://www.frontiersin.org/articles/10.3389/fmicb.2014.00626/full

No toxicity detected for Artemisia annua or afra | MalariaWorldNo toxicity detected for Artemisia annua or afra | MalariaWorld

No toxicity detected for Artemisia annua or afra. August 5, 2019 - 19:06 -- Pierre Lutgen. Artemisias are used since ... Annual Wormwood (Artemisia annua L.)International Journal for Parasitology. 2002 Volume: 32, Issue: 13, Pages: 1655-1660 ... Many studies have shown that Artemisia annua stimulates the immune system. This effect is probably due to other constituents ... Artemisia annua has low poisonous function, and has a promising prospect for potential application. ...
more infohttps://malariaworld.org/blog/no-toxicity-detected-artemisia-annua-or-afra

Use of Artemisia annua L. Infusion for Malaria Prevention : Publications | Carnegie Corporation of New YorkUse of Artemisia annua L. Infusion for Malaria Prevention : Publications | Carnegie Corporation of New York

Use of Artemisia Annua L. Infusion for Malaria Prevention: Mode of Action and Benefits in a Ugandan Community. British Journal ... In this paper we report the use of Artemisia annua L. for malaria prophylaxis at a Ugandan floricultural farm. We conducted a ... annua tea. A. annua variety or product thereof rich in flavonoids but devoid of artemisinin should be developed and tried for ... annua leaf powder used in community indicated the presence of artemisinin (0.4% to 0.5%) and flavonoids (9% to 11%). A. annua ...
more infohttps://www.carnegie.org/publications/use-of-artemisia-annua-l-infusion-for-malaria-prevention/

Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L.Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L.

Y. Y. Tu, M. Y. Ni, and Y. R. Zhong, "Studies on the constituents of Artemisia annua L. and derivatives of artemisinin," ... Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L.. Suganthi Appalasamy ... regulating artemisinin biosynthesis in Artemisia annua L," In Vitro Cellular and Developmental Biology, vol. 47, no. 3, pp. 329 ... 7-dehydroartemisinic acid from Artemisia annua," Journal of Natural Products, vol. 52, no. 1, pp. 196-198, 1989. View at Google ...
more infohttps://www.hindawi.com/journals/bmri/2014/215872/ref/

First-time comparison of the in vitro antimalarial activity of Artemisia annua herbal tea and artemisinin.  - PubMed - NCBIFirst-time comparison of the in vitro antimalarial activity of Artemisia annua herbal tea and artemisinin. - PubMed - NCBI

Artemisia annua tea has been proven to be a very effective treatment for malaria in various clinical trials, but to date its ... First-time comparison of the in vitro antimalarial activity of Artemisia annua herbal tea and artemisinin.. De Donno A1, Grassi ... A study was therefore performed to evaluate the effects of A. annua tea on Plasmodium falciparum cultures in vitro. The ... Quantification of artemisinin in the extract of leaves of A. annua was performed using proton nuclear magnetic resonance ((1)H- ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/22986092

Molecules | Free Full-Text | The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)Molecules | Free Full-Text | The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)

However, A. annua is distinguished from the other members of the family both by the very large number of natural products which ... The phytochemistry of A. annua is dominated by both sesquiterpenoids and flavonoids, as is the case for many other plants in ... annua plants, it has now been possible to demonstrate that dihydroartemisinic acid is a late-stage precursor to artemisinin and ... annua. In the particular case of artemisinin, these in vivo results are also supported by in vitro studies, demonstrating ...
more infohttp://www.mdpi.com/1420-3049/15/11/7603

Ultrasonic assisted extraction of artemisinin from Artemisia Annua L. using monoether-based solvents - Green Chemistry (RSC...Ultrasonic assisted extraction of artemisinin from Artemisia Annua L. using monoether-based solvents - Green Chemistry (RSC...

Solvent extraction is the most widely used method to separate artemisinin from the Chinese medicinal herb Artemisia annua L. In ... Ultrasonic assisted extraction of artemisinin from Artemisia Annua L. using monoether-based solvents Y. Zhang, P. Prawang, C. ... Solvent extraction is the most widely used method to separate artemisinin from the Chinese medicinal herb Artemisia annua L. In ... Ultrasonic assisted extraction of artemisinin from Artemisia Annua L. using monoether-based solvents ...
more infohttps://pubs.rsc.org/en/Content/ArticleLanding/GC/2018/C7GC03191B

Should Artemisia annua (wormwood) tea be used as a prophylactic in endemic countries? | MalariaWorldShould Artemisia annua (wormwood) tea be used as a prophylactic in endemic countries? | MalariaWorld

Artemisia annua can do the same. A resistance to synthetic artemisia analogues has already happened and the increased dosage of ... Artemisia annua tea as a way to eradicate malaria Submitted by jean-Jacques Schul (not verified) on November 12, 2012 - 19:35. ... Should Artemisia annua (wormwood) tea be used as a prophylactic Submitted by K (not verified) on September 1, 2013 - 02:10. My ... A. annua as a prophylactic?. Submitted by Antoniana U. Krettli (not verified) on March 29, 2013 - 14:59. No, the artemisia ...
more infohttps://malariaworld.org/poll/should-artemisia-annua-wormwood-tea-be-used-prophylactic-endemic-countries

FAEC - The essential role of sulfated polysaccharides in <i>artemisia annua</i>...FAEC - The essential role of sulfated polysaccharides in <i>artemisia annua</i>...

The reason may be that they are only soluble in water and most of the Artemisia extracts for research are obtained by organic ... So far the presence of polysaccharides in Artemisia annua has been barely covered in the scientific literature. ... There was 45 times more pure artemisinin fed to the mice than the amount fed via Artemisia annua leaves, yet almost the same ... 625-30). Artemisia annua also contains 3.4 % of sulfur and the acidic polysaccharides it contains are probably sulfated.. ...
more infohttp://www.mitosyfraudes.org/Pesti/sulfated_polysaccharides.html

Artemisia annua: Prospects, Applications and Therapeutic Uses book by Tariq Aftab (Editor), M. Naeem (Editor), M. Masroor A....Artemisia annua: Prospects, Applications and Therapeutic Uses book by Tariq Aftab (Editor), M. Naeem (Editor), M. Masroor A....

Artemisia annua: Prospects, Applications and Therapeutic Uses has 1 available editions to buy at Alibris ... Artemisia annua: Prospects, Applications and Therapeutic Uses by Tariq Aftab (Editor), M. Naeem (Editor), M. Masroor A. Khan ( ... Artemisia annua: Prospects, Applications and Therapeutic Uses. by Tariq Aftab (Editor), M. Naeem (Editor), M. Masroor A. Khan ( ... Artemisia annua is a well-known medicinal plant that has been utilized for a number of purposes, including malaria, for ...
more infohttps://www.alibris.com/Artemisia-annua-Prospects-Applications-and-Therapeutic-Uses/book/38803596

Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase | Biochemical JournalSystematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase | Biochemical Journal

Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase. Xin Fang, Jian-Xu Li, Jin-Quan ... A. annua (E)-β-farnesene synthase; GAS, A. annua germacrene A synthase; NDP, nerolidyl diphosphate; Ni-NTA, nickel ... A. annua amorpha-4,11-diene synthase; AS, Penicillium roqueforti aristolochene synthas; BOS, A. annua α-bisabolol synthase; ... Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase ...
more infohttp://www.biochemj.org/content/474/13/2191

Inducing Effect of Dihydroartemisinic Acid in the Biosynthesis of Artemisinins with Cultured Cells of Artemisia annua by...Inducing Effect of Dihydroartemisinic Acid in the Biosynthesis of Artemisinins with Cultured Cells of Artemisia annua by...

Inducing Effect of Dihydroartemisinic Acid in the Biosynthesis of Artemisinins with Cultured Cells of Artemisia annua by ... "Inducing Effect of Dihydroartemisinic Acid in the Biosynthesis of Artemisinins with Cultured Cells of Artemisia annua by ...
more infohttps://www.hindawi.com/journals/tswj/2014/293190/cta/

Pharmacokinetics of artemisinin delivered by oral consumption of Artemisia annua dried leaves in healthy vs. Plasmodium...Pharmacokinetics of artemisinin delivered by oral consumption of Artemisia annua dried leaves in healthy vs. Plasmodium...

When plant material was present either as mouse chow or Artemisia annua pACT, artemisinin levels in the serum rose to 2.44 and ... The Chinese have used Artemisia annua as a tea infusion to treat fever for >2000 years. The active component is artemisinin. ... Pharmacokinetics of artemisinin delivered by oral consumption of Artemisia annua dried leaves in healthy vs. Plasmodium ... a single oral dose of dried leaves of Artemisia annua (pACT) delivered to Plasmodium chabaudi-infected mice reduced parasitemia ...
more infohttps://www.sigmaaldrich.com/catalog/papers/24661969

Artemisia annua | definition of Artemisia annua by Medical dictionaryArtemisia annua | definition of Artemisia annua by Medical dictionary

Artemisia annua explanation free. What is Artemisia annua? Meaning of Artemisia annua medical term. What does Artemisia annua ... Looking for online definition of Artemisia annua in the Medical Dictionary? ... Artemisia annua. Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.. Related to Artemisia annua: Artemisia ... Treatment with Artemisia annua was performed by Dr.. Activity of Artemisia annua and artemisinin derivatives, in prostate ...
more infohttps://medical-dictionary.thefreedictionary.com/Artemisia+annua
  • This observation forms the basis of a proposal that the biogenesis of many of the highly oxygenated terpene metabolites from A. annua - including artemisinin itself - may proceed by spontaneous oxidation reactions of terpene precursors, which involve these highly reactive allyllic hydroperoxides as intermediates. (mdpi.com)
  • Part II: chemical, toxicological, pharmacological and microbiological profiles of Artemisia annua L. volatiles. (malariaworld.org)
  • Paired with the relatively low demand on the environment Artemisia annua can have characteristics of a neophytic plant. (wikipedia.org)
  • The most convincing human trial on toxicity of the Artemisia plant comes from Uganda. (malariaworld.org)
  • When plant material was present either as mouse chow or Artemisia annua pACT, artemisinin levels in the serum rose to 2.44 and 4.32 mg L(-1), respectively, indicating that the presence of the plant matrix, even that of mouse chow, had a positive impact on the appearance of artemisinin in the blood. (sigmaaldrich.com)
  • Artemisinin is the active pharmaceutical ingredient (API) of Artemisia annua plant. (thefreedictionary.com)
  • Most recently, she has been experimenting with a therapeutic regime that involves administering the Artemisia annua plant itself in the form of ground leaves pressed into tablets or placed in capsules. (thefreedictionary.com)
  • Together, these enzymes produce specialized triterpenoids that are constituents of the wax layer of the cuticle covering the aerial parts of A. annua and likely function in the protection of the plant against biotic and abiotic stress. (plantcell.org)
  • he Latin name Artemisia annua already refers to the fact that the plant grows annual. (magicgardenseeds.com)
  • Epi-deoxy-arteannuin B and 6,7-dehydroartemisinic acid from Artemisia annua . (springer.com)
  • And over the months they noticed that Artemisia annua has a strong prophylactic effect. (mitosyfraudes.org)
  • In this study, we showed the leishmanicidal effect of essential oil from Artemisia annua leaves (AALEO) against Leishmania donovani in vitro and in vivo . (frontiersin.org)
  • Chemical Composition and Antioxidant and Antimicrobial Activity of Essential Oil of Artemisia annua L. (thefreedictionary.com)
  • Studies on the constituents of Artemisia annua . (springer.com)
  • Y. Y. Tu, M. Y. Ni, and Y. R. Zhong, "Studies on the constituents of Artemisia annua L. and derivatives of artemisinin," Zhongguo Zhong Yao Za Zhi , vol. 6, no. 31, 1981. (hindawi.com)
  • In addition, polysaccharide constituents of A. annua may enhance bioavailability of artemisinin. (ac.ke)
  • In traditional Chinese medicine (TCM), A. annua is traditionally used to treat fever. (wikipedia.org)
  • The identification of a novel double bond reductase in A. annua provides an opportunity to explore the mechanism underlying the detoxification of aldehyde ketone molecules, which are generated by HPL downstream pathway and the redox process in the metabolic pathway of artemisinin synthesis. (springer.com)
  • We isolated a 2-alkenal reductase (AaAER) gene from Artemisia annua L. cDNA library through homologous cloning strategy. (springer.com)
  • The full-length cDNA sequence of AaERF3 was cloned and characterized from Artemisia annua . (springer.com)
  • Artemisia annua produces 400,000 to 800,000 daily doses of treatment per hectare in reasonable growing conditions. (timothywise.com)
  • Cultivating Artemisia annua and producing and testing the tablets, according to Weathers, are ideal local businesses that can provide jobs in impoverished areas and greatly expand access to antimalarial therapy. (escop.com)
  • According to this researcher, this is the first case of control of a resistant strain in humans with leaf of Artemisia annua , which would support its incorporation into the antimalarial treatment regime where resistant strains emerge. (escop.com)
  • The growing period of Artemisia annua from seeding till harvest is 190-240 days, depending on the climate and altitude of the production area. (wikipedia.org)
  • Using warm water is a simple and affordable treatment especially to local farmers which will give the best result in the germination and seedling production of A. annua. (davesgarden.com)
  • Thus, breeding programs for A. annua seek to select late-flowering genotypes with high artemisinin contents and high leaf biomass production, which facilitates an increase in the production of artemisinin from 5 kg ha -1 to 25 kg ha -1 (Magalhães et al. (scielo.br)
  • Most of the polysaccharids in Artemisia tripartita are sulfated and inhibit ROS production ( G Xie et al. (mitosyfraudes.org)