ArsphenamineIndiaClavulanic Acid: Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.beta-Lactamases: Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.beta-Lactams: Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.Clavulanic Acids: Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Amoxicillin: A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Salmonella typhimurium: A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER.Mutagenicity Tests: Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.Mutagens: Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.Lipopolysaccharides: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Histidine: An essential amino acid that is required for the production of HISTAMINE.Salmonella enterica: A subgenus of Salmonella containing several medically important serotypes. The habitat for the majority of strains is warm-blooded animals.Glass: Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.Alexander Disease: Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.History, 20th Century: Time period from 1901 through 2000 of the common era.AccidentsHistory, 19th Century: Time period from 1801 through 1900 of the common era.Famous PersonsSulfacetamide: An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.Sulfapyridine: Antibacterial, potentially toxic, used to treat certain skin diseases.Sulfamethizole: A sulfathiazole antibacterial agent.Thiamphenicol: A methylsulfonyl analog of CHLORAMPHENICOL. It is an antibiotic and immunosuppressive agent.Penicillin G Benzathine: Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.Sulfamerazine: A sulfanilamide that is used as an antibacterial agent.Tropical Medicine: The branch of medicine concerned with diseases, mainly of parasitic origin, common in tropical and subtropical regions.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Randomized Controlled Trials as Topic: Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.Haptens: Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response.Arsenicals: Inorganic or organic compounds that contain arsenic.Local Lymph Node Assay: The local lymph node assay (LLNA) is an alternative method for the identification of chemicals that have the ability to cause skin sensitization and allergic contact dermatitis. Endpoints have been established so fewer animals are required and less painful procedures are used.Dermatitis, Allergic Contact: A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.Animal Testing Alternatives: Procedures, such as TISSUE CULTURE TECHNIQUES; mathematical models; etc., when used or advocated for use in place of the use of animals in research or diagnostic laboratories.Cosmetics: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)Immune Tolerance: The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.Lindane: An organochlorine insecticide that has been used as a pediculicide and a scabicide. It has been shown to cause cancer.Scurvy: An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. Scurvy is characterized by bleeding in any tissue, weakness, ANEMIA, spongy gums, and a brawny induration of the muscles of the calves and legs.Micronesia: The collective name for islands of the Pacific Ocean east of the Philippines, including the Mariana, PALAU, Caroline, Marshall, and Kiribati Islands. (From Webster's New Geographical Dictionary, 1988, p761 & Room, Brewer's Dictionary of Names, 1992, p350)History, 18th Century: Time period from 1701 through 1800 of the common era.Gene Library: A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Gift Giving: The bestowing of tangible or intangible benefits, voluntarily and usually without expectation of anything in return. However, gift giving may be motivated by feelings of ALTRUISM or gratitude, by a sense of obligation, or by the hope of receiving something in return.Conflict of Interest: A situation in which an individual might benefit personally from official or professional actions. It includes a conflict between a person's private interests and official responsibilities in a position of trust. The term is not restricted to government officials. The concept refers both to actual conflict of interest and the appearance or perception of conflict.Industry: Any enterprise centered on the processing, assembly, production, or marketing of a line of products, services, commodities, or merchandise, in a particular field often named after its principal product. Examples include the automobile, fishing, music, publishing, insurance, and textile industries.Drug Discovery: The process of finding chemicals for potential therapeutic use.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Research Support as Topic: Financial support of research activities.

Paul Ehrlich: pioneer of chemotherapy and cure by arsenic (1854-1915). (1/2)

Paul Ehrlich's experiments in staining techniques at the end of the nineteenth century resulted in many discoveries which help to form the basis of present research work. Ehrlich's chemotherapy research led to his formulating the arsenic compound, Salvarsan, which was used in the treatment of syphilis during the first half of this century until it was superseded by penicillin.  (+info)

Arsphenamine jaundice and the recognition of instrument-borne virus infection. (2/2)

Soon after its introduction in 1910, intravenous arsphenamine treatment for syphilis was found to be complicated by jaundice. The underlying cause, unsterile syringes and needles, was eventually recognised in the early 1940s, mainly through the efforts of British Army investigators. The infection most often transmitted was probably hepatitis B virus (HBV), but the high mortality in a few of the outbreaks of arsphenamine jaundice suggests that variants of HBV, or other hepatitis viruses, were sometimes involved. Fifty years later, at a time when there are estimated to be over three hundred million carriers of HBV in the world and probably at least as many hepatitis C virus carriers, and when the World Health Organisation estimates that there have been 17 million infections with human immunodeficiency virus, the lessons learnt around 1945 about the need to use sterile instruments and needles for all injections and venepunctures remain highly pertinent.  (+info)

TRIVENI INTERCHEM PVT. LTD. - Exporter, Manufacturer, Distributor, Supplier, Trading Company of Arsphenamine based in Vapi, India
The development of drugs for the treatment of infectious diseases was a major focus of early research and development efforts; in 1900 pneumonia, tuberculosis, and diarrhea were the three leading causes of death in the United States and mortality in the first year of life exceeded 10%.[12][13]. In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan.[14] Ehrlich, noting both the general toxicity of arsenic and the selective absorption of certain dyes by bacteria, hypothesized that an arsenic-containing dye with similar selective absorption properties could be used to treat bacterial infections. Arsphenamine was prepared as part of a campaign to synthesize a series of such compounds, and found to exhibit partially selective toxicity. Arsphenamine proved to be the first effective treatment for syphilis, a disease which prior to that ...
This is the timeline of antimicrobial (anti-infective) therapy. The years show when a given drug was released onto the pharmaceutical market. This is not a timeline of the development of the antibiotics themselves. 1911 - Arsphenamine a.k.a. Salvarsan 1912 - Neosalvarsan 1935 - Prontosil (an oral precursor to sulfanilimide), the first sulfonamide 1936 - Sulfanilimide 1938 - Sulfapyridine (M&B 693) 1939 - sulfacetamide 1940 - sulfamethizole 1942 - benzylpenicillin, the first penicillin 1942 - gramicidin S, the first peptide antibiotic 1942 - sulfadimidine 1943 - sulfamerazine 1944 - streptomycin, the first aminoglycoside 1947 - sulfadiazine 1948 - chlortetracycline, the first tetracycline 1949 - chloramphenicol, the first amphenicol 1949 - neomycin 1950 - oxytetracycline 1950 - penicillin G procaine 1952 - erythromycin, the first macrolide 1954 - benzathine penicillin 1955 - spiramycin 1955 - tetracycline 1955 - thiamphenicol 1955 - vancomycin, the first glycopeptide 1956 - ...
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애플의 기본 프로그램인 포토부스의 멋진 그래픽 필터 효과들을 사용해 본 경험이 있으세요? Paul Neave씨는 브라우저만으... (이 페이지는 태그 WebGL(으)로 필터링 되었습니다.)
Most of First Corinthians is Paul telling the people in the church there that they are not doing the right things by God, and he gives them advice on how to fix their actions ...
Interpretare si rationalitate - Paul Cornea - - Lucrarea constituie o explorare monografica a interpretarii, ca demers corectiv, explorator, mediator, explicat
Icons made by Dave Gandy from www.flaticon.com is licensed by CC 3.0 BY. Icons made by Madebyoliver from www.flaticon.com is licensed by CC 3.0 BY. ...
Tarihçe Paul Ansbro 1946 Supraklavikular Kateter Selander Aksiller Kateter Tuominen İnterskalen Kateter Boezaart Stimüle Edici Kateter
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Drie namen, twee stijlen en n dubbelaar. Paul Elstak en Lunatic & Miss Hysteria zijn verantwoordelijk voor de nieuwste Hardcore Heroes mix cd. De tracklist is verassend en maakt ons in ieder geval nieuwsgierig om te luisteren wat deze iconen uit de scene neerzetten ...
There are four categories of Ron Paul voters. The first category is made up of true Paul supporters. They vote for Paul because they truly believe in his p
... Hardcastle Paul Miscellaneous 19 19 by Paul Hardcastle send any corrections to [email protected] In 1965 Vietnam seemed like just ano
Paul Bettany Directs Wife Jennifer Connelly for Shelter: Photo #2959313. Jennifer Connelly gives a coy smile while receiving a note from her director and husband Paul Bettany on the set of their latest film Shelter on Monday (September…
Excel 2016 Formulas and Functions (includes Content Update Program) (Heftet) av forfatter Paul McFedries. Pris kr 289. Se flere bøker fra Paul McFedries.
PAUL DARCY is a Group 1, Classic winning trainer, based in Newmarket. Since starting out in 1998, Paul has achieved great success from a very small number of horses and has demonstrated his ability to achieve excellent results at the top level.
If you thought that title meant Pope John Paul II, you wouldnt be faulted. Thats logical and in fact, Im sure theres truth to it. But Im talking here about John Paul Kilners story: Nothing can prepare you for seeing...
Explore some of Paul Erlich best quotations and sayings on Quotes.net -- such as The first rule to tinkering is to save all the parts. and more...
The Anoka-Hennepin district made the announcement early Monday afternoon, and was soon followed by Minneapolis, St. Paul and others.
Paul S. Wheatley is the author of this article in the Journal of Visualized Experiments: Synthese van zeolieten met behulp van de ADOR (Assembly-Demontage-Organisatie-Montage) Route
Visit Healthgrades for information on Paul Teri Find Phone & Address information, medical practice history, affiliated hospitals and more.
Paul J. Cordo is the author of this article in the Journal of Visualized Experiments: Methode om Tone van axiale en proximale spier te meten
The senator doesnt recognize gay rights as a real issue because rights based on behavior lack legitimacy. Paul may not have thought this one through.
I want your news tips, especially in and near Minnesota. I write whats interesting and important, with interesting being my preference. Follow @walshpj
The aim of my writing is to illuminate and guide others to create positive change in the worldI do this through: - Being curious and sharing...
Lab+Life Scientist magazine and LabOnline website providing The latest industry news, articles, Case studies, products, directory, Events
Barry found a couple of very good words to take the early lead. Paul got some of the ground back in the first numbers round, but then Barry extended it again in round four. Paul managed to match Barry in the fifth round, and another good numbers result put him only a little behind. Then Barry faltered in the last letters round and Paul took the lead for the first time in the game. Neither contestant was able to make any headway on the last numbers round, and the conundrum also proved to be too difficult for them both. Paul wobbled home with the win, 31 to 26 ...
Paul McCartney Drive My Car Lyrics. Drive My Car lyrics performed by Paul McCartney: Asked a girl what she wanted to be She said baby, cant you see I wanna be famous, a star on the screen But you can do something in between
See ratings and reviews, wine tasting notes, food pairings, and find where to buy Vintage 2008 Domaine Paul Autard Red Rhone Blend Châteauneuf-du-Pape Cuvée la Cote Ronde
Xavier Paul is going to try to take advantage of Manny Ramirezs 50-game suspension.Paul was called up to take Mannys spot on the Dodgers 25-man roster after hitting .344 with a pair of home runs, eight stolen bases, and a ...
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paul can type 60 words per minute and jen can type 80 words per minute. how dose puls typing speed compare to jen? 1.Paul can type 1/4 as fast as Jen. 2.Paul can type 1/3 as fast as Jen. 3.Paul can type 3/4 as fast as Jen. 4.Paul can type 1 1/3 times as fast as Jen. i think ... ...
Paul OGrady has shared a throwback to his days on The Bill that had his followers on Instagram comparing him to a stripper. Read more here.
Quit Smoking Today Without Gaining Weight von McKenna, Paul beim ZVAB.com - ISBN 10: 140276572X - ISBN 13: 9781402765728 - Sterling Pub - 2011 - Hardcover
Study GI Drugs flashcards from paul heggem's class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
Featuring Polarized, Polycarbonate lenses set in a lightweight & stylish frame, find out why Jonathan Paul has been making the best Fitovers for over 20 years, thanks in part to their best in class fit and proven technology.
Lyrics to Ac-Cent-Tchu-Ate The Positive by Paul McCartney: Gather round me, everybody / Gather round me, while I preach some / Feel a
For Sale - 2990 St Paul Road Ne, Owatonna, MN - $17,490. View details, map and photos of this lots/land property with 0 bedrooms and 0 total baths. MLS# 2918146.
Dr. Paul I. Terasaki, HLA Pioneer, founder of One Lambda, Inc. and founder of the Terasaki Foundation, passed away the morning of January 25, 2016 at his home in Los Angeles.
Hey Baby lyrics by Sean Paul: Sexy ladies in the place / You know how we do it / [Hook] / Hey baby trinna find what you driving me crazy
Visit Paul Berntsons CaringBridge website where youll find the latest updates and a place to share messages of love, hope & compassion.
By all accounts this schismatic man is engaging in the behavior condemned by Paul in v. 9. The heretic, in this context, is someone who is causing division within the church. Before you run out and begin to pronounce everyone a heretic, due care must be given to the particulars. First, what makes a heretic divisive is not simply his disagreement with Paul and Titus. It is the nature of his disagreement with them. Barnabas disagreed with Paul and he was not pronounced a heretic. Their disagreement was so sharp that they ceased working together. And yet Barnabas was never pronounced a heretic. Mere disagreement does not equal schismatic behavior. We should take care not to engage in malicious and slanderous practices by pronouncing those who have mere disagreements with us to be heretics or divisive. After all, Paul says in 3:2 that we are to malign no one. This word is the same word that is translated "blaspheme" and it means to speak about someone in a disrespectful way that demeans and ...
By Jake Crosby Like Seth Mnookin did earlier this month, Paul Offit blatantly lied about me while giving a lecture. The congressionally reprimanded millionaire vaccine industrialist told a room full of people I was a
Download - - - (right-click, then click Save Link As) Ron Paul: This may well be the last time I speak on the House Floor. At the end of the year Ill l
Visit Healthgrades for information on Dr. Paul Weiden, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Jerry Landis is Paul Simon, back before he got in touch with his Greenwich Village side. He actually recorded under several pseudonyms before folking himself into our lives. "The Lone Teen Ranger," which doesnt make any narrative sense (but neither did "Duke of Earl"), got up to #99 on the American charts. It was released in 1962, five years after The Lone Ranger went off TV, so it wasnt exactly the timeliest of releases. Its cute to hear Simon do the doo-wop versicles at the beginning and throughout the track ...
My therapist is always aware of issues that impact my sense of efficacy (since its rather low), and Paul acting this way seems to be strongly implying that Jesse cant get by without therapy with Paul, or that he cant have gained ANYTHING from their time together if things dont go in the future the way that PAUL wants them to go; it has nothing to do with anything Jesse does, at all, completely taking anything and everything away from him, that he participates in the therapy ...
Innovative modifications to processes can improve productivity, helping producers and manufacturers succeed in a challenging global environment. View full article › ...
Posted on Tuesday, 5th January 2016. BIGGA would like to welcome James Hutchinson to the team who has accepted the newly created role of Sustainability Executive.. James was previously Environmental Officer at St Andrews. Prior to that he was Ecology Manager at Fairhaven Golf Club in Lytham, Lancashire.. This new role will involve James working closely with the Golf Environment Organisation and other industry bodies to uncover and promote examples of good sustainability practice on golf courses among the BIGGA membership, and demonstrate our members commitment to sustainability.. James will also have an influence on our Learning & Development activity which will have an even more increased focus on this topical issue.. It is intended that BIGGA will offer a range of environmental and sustainability advisory services to its members and their golf clubs, as an acknowledged expert in his field with a successful track record in providing environmental plans James is an outstanding candidate to ...
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(CNN) - Sen. Rand Paul rushed to show support Tuesday for slain Navy sniper Chris Kyle after Pauls father, former Rep. Ron Paul, drew criticism for asserting a political opinion in a Tweet about Kyles death. Chris Kyle was a hero like all Americans who don the uniform to defend our country.
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Health,... MOORESVILLE N.C. Aug. 1 /- Anpath Group ... We are very pleased to have Paul Boyer and Dave Gilroy join our board...Mr. Breedlove highlighted Messrs. Boyers and Gilroys qualifications... Paul Boyer brings over 20 years of experience as a finance andoperat...,Anpath,Group,,Inc.,Announces,Appointments,of,David,V.,Gilroy,and,Paul,A.,Boyer,to,Board,of,Directors,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
We should remember that the New Testament, as we have it, is much more dominated by Paul than appears at first sight. As we read it, we come across the Four Gospels, of which Jesus is the hero, and do not encounter Paul as a character until we embark on the post-Jesus narrative of Acts. Then we finally come into contact with Paul himself, in his letters. But this impression is misleading, for the earliest writings in the New Testament are actually Pauls letters, which were written about AD 50-60, while the Gospels were not written until the period AD 70-110. This means that the theories of Paul were already before the writers of the Gospels and coloured their interpretations of Jesus activities. Paul is, in a sense, present from the very first word of the New Testament. This is, of course, not the whole story, for the Gospels are based on traditions and even written sources which go back to a time before the impact of Paul, and these early traditions and sources are not entirely obliterated in ...
We should remember that the New Testament, as we have it, is much more dominated by Paul than appears at first sight. As we read it, we come across the Four Gospels, of which Jesus is the hero, and do not encounter Paul as a character until we embark on the post-Jesus narrative of Acts. Then we finally come into contact with Paul himself, in his letters. But this impression is misleading, for the earliest writings in the New Testament are actually Pauls letters, which were written about AD 50-60, while the Gospels were not written until the period AD 70-110. This means that the theories of Paul were already before the writers of the Gospels and coloured their interpretations of Jesus activities. Paul is, in a sense, present from the very first word of the New Testament. This is, of course, not the whole story, for the Gospels are based on traditions and even written sources which go back to a time before the impact of Paul, and these early traditions and sources are not entirely obliterated in ...
From the American Dream to Presence (Productions) My friend-in-music and frequent contributor to this site, Paul Payton, has indeed live and continue to live the life of music. Over the years - via Pauls official comments to this site, I was often intrigued by his background in the world of Rock and Roll (and Country,…
DEATH RACE is a film for no one. Neither bloody enough to please the gorehounds, nor trashy enough to qualify as a transgressive pleasure, Paul W.S. Andersons lobotomization of Paul Bartels futuristic satire is just a mindless onslaught...
Deep Relaxation By Paul Haider Notes written by Paul Haider, Well Known Author and Keynote Speaker What is everyone looking for these days? They are all lo
12 Senior Accounting Analyst Salaries in Minneapolis-St. Paul, MN provided anonymously by employees. What salary does a Senior Accounting Analyst earn in Minneapolis-St. Paul?
Paul Reilly is president of Reilly Sales Training a St. Louis-based, privately owned company that specializes in training sales professionals, sales managers, and service professionals. He can be reached at 636-778-0175 or [email protected] ReillySalesTraining.com to sign up for his free newsletter.. ...
MAN RAY (American, 1890-1976) Paul and Nusch Eluard, circa 1930 Vintage gelatin silver 4-1/4 x 3-1/8 inches (10.8 x 7.9 - Available at 2012 May 1 Photographs...
In the face of a life-changing accident climber Paul Pritchard continued to beat the odds thanks to his determination, resilience and strength.
DentalPlans detailed profile of Paul Nativi , DDS - Dentist in 62095. View plans, sample savings & pricing, patient reviews & practice information.
TY - JOUR. T1 - TRAPIANTO DI FEGATO. T2 - LESPERIENZA DELLOSPEDALE PAUL BROUSSE. AU - Bismuth, H.. AU - Meriggi, F.. AU - Forni, E.. PY - 1989. Y1 - 1989. UR - http://www.scopus.com/inward/record.url?scp=0024950972&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0024950972&partnerID=8YFLogxK. M3 - Articolo. C2 - 2518304. AN - SCOPUS:0024950972. VL - 10. SP - 365. EP - 368. JO - Giornale di Chirurgia. JF - Giornale di Chirurgia. SN - 0391-9005. IS - 7-8. ER - ...
Painted by Paul Brent, the Patchwork Foliage wall mural from Murals Your Way will add a distinctive touch to any room. Choose a pre-set size, or customize to your wall.
Meet Dr. Montalbano - Dr. Paul Montalbano is a neurosurgeon in Boise, Idaho and has been practicing neurosurgery for over 22 years. He received his medical
Case opinion for US 10th Circuit TENNILLE v. Sikora Nelson; Paul Dorsey, Objectors-Appellants.. Read the Courts full decision on FindLaw.
Here is a column idea for Paul Krugman (you remember him - he used to be talked about, before the Times Reject debacle?). The setting is Princeton, NJ, which is Krugmans hometown. The theme is the minority achievement gap in...
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Visit DocBios.com for information about Paul W. Kampfe, M.D., P.C.. Find Phone & Address information, specialties, ratings and more
One more flu update. I think we have peaked in the epidemic in North America. Here is a short update. Good luck, Paul paulherscuepidemics.blogspot.com ...
Sen. Rand Paul says parents should have some input when it comes to getting their children vaccinated. CNNs Dana Bash, Gloria Borger, and Wolf Blitzer discuss.
Information about Paul Smiths College RN program. Completion of an accredited nursing program or other medical training, can qualify you to start working immediately.
If someone comes out of a liquor store with a weapon and fifty dollars in cash I dont care if a drone kills him or a police man kills him... - Rand Paul
See what Paul Maguire (paulathebarn) has discovered on Pinterest, the worlds biggest collection of everybodys favorite things.
Paul S. Linker, MD is a practicing Pediatrician in Summerville, SC. Dr. Linker graduated from Medical University of South Carolina College of Medicine in 1...
Los Angeles Clippers point guard Chris Paul and Cleveland Cavaliers big man Anderson Varejao were both warned by the league for flopping.
As a surgeon, Dr. Paul Bjordahl, MD, specializes surgery, critical care and adult trauma, offering the latest in surgical care at Sanford Surgical Associates.
Welcome to the new SheKnows Community,. where you can share your stories, ideas. and CONNECT with millions of women.. Get Started ...
Im still working on the numbers, but Ive gotten a fair number of requests for comment on the Senate version of the stimulus. The short answer: to appease the centrists, a plan that was already too small and too focused on ineffective tax cuts has been made significantly smaller, and even more focused on tax cuts.
The Administrative Core (AC) serves as the central coordinating center that manages and integrates the multiple program activities carried out at the ADCS and c...
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Spring is almost here, so you should feel the urge to start traveling again. Nothing compares to that feeling of freedom you get when you are on the road, ready…. ...
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but that didnt stop fans from poring over the Beatles albums for "clues" to Pauls untimely demise. Many of the supposed clues to Pauls death are simply vague references to death. Other clues are pictures of the Beatles that show Paul in a manner that is different from the other Beatles in some way, especially involving the colors red (blood) or black (death). Most of the "Paul is dead" clues are simply the product of an obsessive search for significance, but a few are genuinely chilling. The Beatles all denied that they had perpetrated a hoax and insisted that none of the "clues" about Pauls supposed death had any significance whatsoever. According to Ringo, "Its all a load of crap." When asked if he had intentionally placed any of the clues, John denied it in similar terms, "No. That was bullshit, the whole thing was made up." Lennon Remembers (New York: Popular Library, 1971), p. 97.. When Detroit DJ Russ Gibb spoke on the air about Paul McCartneys rumored death, the story had already ...
but that didnt stop fans from poring over the Beatles albums for "clues" to Pauls untimely demise. Many of the supposed clues to Pauls death are simply vague references to death. Other clues are pictures of the Beatles that show Paul in a manner that is different from the other Beatles in some way, especially involving the colors red (blood) or black (death). Most of the "Paul is dead" clues are simply the product of an obsessive search for significance, but a few are genuinely chilling. The Beatles all denied that they had perpetrated a hoax and insisted that none of the "clues" about Pauls supposed death had any significance whatsoever. According to Ringo, "Its all a load of crap." When asked if he had intentionally placed any of the clues, John denied it in similar terms, "No. That was bullshit, the whole thing was made up." Lennon Remembers (New York: Popular Library, 1971), p. 97.. When Detroit DJ Russ Gibb spoke on the air about Paul McCartneys rumored death, the story had already ...
Paul Hickert, Actor: The Defenders. Paul Hickert is known for his work on The Defenders (2017), Mindhunter (2017) and Law & Order: Special Victims Unit (1999).
County of St. Paul No. 19 is located in NE Alberta, Canada. Our communities are diversified in mixed agriculture, oil and gas industry and offer great tourist attractions.
E. Paul Kelly fire battalion chief E. Paul Kelly, 79, of Frontier Road, died December 5, 2011 at Rhode Island Hospital. He was the beloved husband of the late Jacqueline E. (Babin) Kelly, to …
Paul Penders range of natural skin care products are not new to me but I had absolutely no idea that this Dutch brand is actually based in the Langkawi island in Malaysia! Interestingly, this brand has been around for over 40 years in Holland but it was only in 2003 that founder, Paul Penders, discovered the
Get an answer for What is a summary of Paul Austers Mr. Vertigo? and find homework help for other Paul Auster questions at eNotes
1 review and complaint on Dr. Paul Daniel Corona - United States - Dr. Paul Daniel Corona accused of fueling fatal overdoses - Rated 1 out of 5 based on 1 review
Paul Ferguson, 42, is accused of shooting 15-year-old Della Jette and her 16-year-old brother, Sterling Jette Jr., in their chests at the home in Watertown Tuesday night, according police told NBC Connecticut.
Paul Forsyth Cardiac Alert Dog for Lindsey Lindsey and I have been together for 20 years and moved to Australia 10 years ago with the hope of raising a famil
Vinnie Paul Abbott's cause of death has been revealed. The 54-year-old PANTERA and HELLYEAH drummer died of dilated cardiomyopathy - an enlarged he...
The midseason premiere of Greys Anatomy ended with quite the WTF moment. Star Camilla Luddington discusses the Paul mystery and whats next - interview
Promoters of a traveling exhibit of artifacts and memorabilia belonging to Pope John Paul II will reveal more details of the tour beginning next year in Lubbock.
... , Sabaton, Demi Lovato, Pavle Kavec, Leonard Cohen, 3 Doors Down, Gavin Degraw, Tragically Hip, Cradle Of Filth, Sleigh Bells, Artes, M.I.A., Mitja Podlesnik, David, Alex Volasko, Sam, Oko, Toots Thielemans, Backstreet Boys, *NSYNC.. ...
Get the facts about Paul Smiths College RN degrees. Whether you are considering an associates degree (CNA, LVN, or LPN), or a bachelor of science in nursing (RN), you will find many doors opening after graduation.
1911 - Arsphenamine a.k.a. Salvarsan 1912 - Neosalvarsan 1935 - Prontosil (an oral precursor to sulfanilimide), the first ...
The first time a drug was systematically improved was with arsphenamine (Salvarsan). Numerous derivatives of the dangerously ...
With this new knowledge, Ehrlich tested Compound 606 (chemically arsphenamine) on a syphilis-infected rabbit. On 31 August 1909 ... Williams, K. (2009). "The introduction of 'chemotherapy' using arsphenamine - the first magic bullet". Journal of the Royal ...
Williams KJ (2009). "The introduction of 'chemotherapy' using arsphenamine - the first magic bullet". J R Soc Med. 102 (8): 343 ...
This drug is now known as arsphenamine.[101] The drug was used to treat syphilis in the first half of the 20th century. In 1908 ... "The introduction of 'chemotherapy' using arsphenamine - the first magic bullet". Journal of the Royal Society of Medicine. 102 ...
At the time of the outbreak of World War I, the only effective treatments for syphilis were based on arsphenamine which was ... As early as March, 1916 the Research Institute was supplying arsphenamine to all 48 states and to the military. In Nov of 1917 ... Early in the war the Research Institute developed a process for the manufacture of arsphenamine. By early 1916, the supply of ...
The company Farbwerke Hoechst marketed arsphenamine as the drug Salvarsan, "the arsenic that saves". Its specificity of action ... Ehrlich and Bertheim's 606th arsenobenzene, synthesized in 1907, was arsphenamine, found ineffective against trypanosomes, but ...
The number 606 would become the slang name for the treatment with Salvarsan, the trade name for arsphenamine. Born: Ferenc ... Paul Ehrlich found the first successful treatment for syphilis, arsphenamine, on his 606th experiment. The compound, based on ...
"The introduction of 'chemotherapy' using arsphenamine - the first magic bullet". J R Soc Med 102 (8): 343-8. PMC 2726818. PMID ...
The first modern chemotherapeutic agent was arsphenamine, an arsenic compound discovered in 1907 and used to treat syphilis. ...
The Abelin reaction is a qualitative reaction for demonstrating the presence of arsphenamine and neoarsphenamine in blood and ...
... (1879-1965) was a German born ophthalmologist known for his work on arsphenamine for the treatment of ...
A representative leader was Joseph Igersheimer (1879-1965), best known for his discoveries with arsphenamine for the treatment ...
Arsphenamine proved to be the first effective treatment for syphilis, a disease which prior to that time was incurable and led ... Arsphenamine was prepared as part of a campaign to synthesize a series of such compounds, and found to exhibit partially ... Compared to arsphenamine, the sulfonamides had a broader spectrum of activity and were far less toxic, rendering them useful ... In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the ...
When the study started, arsphenamine (Salvarsan) and Neosalvarsan were the only available treatments for syphilis, and both ...
By 1910 Paul Ehrlich and his laboratory group began developing arsenic-based arsphenamine, (Salvarsan), as the first effective ...
... arsphenamine MeSH D02.691.088.060 --- p-azobenzenearsonate MeSH D02.691.088.100 --- cacodylic acid MeSH D02.691.088.500 --- ...
Arsphenamine, the first modern chemotherapeutic agent 1909 - Fritz Haber: Haber Process for industrial production of ammonia ...
The drug "606" or "compound 606", which became known as arsphenamine Roland TR-606 Drum Machine 606 (radio show), the BBC Radio ...
... where he assisted Paul Ehrlich in the discovery of arsphenamine, which proved effective in curing syphilis. It was called ... was a prominent Japanese bacteriologist who assisted in developing the Arsphenamine drug in 1909 in the laboratory of Paul ...
Hoechst AG market Arsphenamine under the trade name Salvarsan, the first organic antisyphilitic, its properties having been ...
The first synthetic antimicrobial drug, arsphenamine, discovered in 1909 by Sahachiro Hata in the laboratory of Paul Ehrlich, ...
The first antibiotic was arsphenamine (Salvarsan) discovered by Paul Ehrlich in 1908 after he observed that bacteria took up ...
99,0 99,1 «The introduction of 'chemotherapy' using arsphenamine - the first magic bullet»։ Journal of the Royal Society of ...
Exporter, Manufacturer, Distributor, Supplier, Trading Company of Arsphenamine based in Vapi, India ...
The Effect of Arsenic Preparations (Neoarsphenamine and Silver Arsphenamine) on the Protein Fractions of Blood Plasma in ...
Arsphenamine. 03.21.2013 Author: admin Category: Antibiotics 0 Comment » The arsphenamine, more known as Salvarsan and 606, is ...
Because of the popularity of beta-lactam drugs, certain bacteria have been able to develop counter-measures to traditional drug therapies. An enzyme called beta-lactamase is present in many different types of bacteria, which serves to break the beta lactam ring, which effectively nullifies the antibiotics effectiveness. An example such enzyme is the NDM-1 discovered in 2009.. As a response to bacterial resistance to beta-lactam drugs, there are drugs, such as Augmentin/CLA, that are designed to disable the beta-lactamase enzyme. Augmentin/CLA (FGP) is made of amoxicillin, a beta-lactam antibiotic, and clavulanic acid, a beta-lactamase inhibitor. The clavulanic acid is designed to overwhelm all beta-lactamase enzymes, bind irreversibly to them, and effectively serve as an antagonist so that the amoxicillin is not affected by the beta-lactamase enzymes.. Full article ▸. ...
The test uses several strains of the bacterium Salmonella typhimurium that carry mutations in genes involved in histidine synthesis i.e. it is a auxotrophic mutant, so that they require histidine for growth. The variable being tested is the mutagens ability to cause a reversion to growth on a histidine-free medium. The tester strains are specially constructed to have both frameshift and point mutations in the genes required to synthesize histidine, which allows for the detection of mutagens acting via different mechanisms. Some compounds are quite specific, causing reversions in just one or two strains.[3] The tester strains also carry mutations in the genes responsible for lipopolysaccharide synthesis, making the cell wall of the bacteria more permeable,[4] and in the excision repair system to make the test more sensitive.[5] Rat liver extract is optionally added to simulate the effect of metabolism, as some compounds, like benzo[a]pyrene, are not mutagenic themselves but their metabolic ...
Arsphenamine was important not only because it was the first synthetic compound to kill a specific invading microorganism but ... history of medicine: Ehrlich and arsphenamine. Their success inaugurated the chemotherapeutic era, which was to revolutionize ...
1911 - Arsphenamine a.k.a. Salvarsan 1912 - Neosalvarsan 1935 - Prontosil (an oral precursor to sulfanilamide), the first ...
The first time a drug was systematically improved was with arsphenamine (Salvarsan). Numerous derivatives of the dangerously ...
1911 - Arsphenamine a.k.a. Salvarsan 1912 - Neosalvarsan 1935 - Prontosil (an oral precursor to sulfanilimide), the first ...
6. Neo-arsphenamine by rectum is efficacious. * 7. Colloidal quinine (Colobiases de Quinine-Dausse), in doses of 1 grain (0.065 ... 5. Neo-arsphenamine in concentrated solutions-as much as 0.9 gram in 2 cc.-fulfills all essential requirements of the higher ... 4. The arsphenamines promptly abort acute attacks in all forms of malaria, and are specifics in the tertian field. ...
1907 - Arsphenamine, first modern medicine ,, No, any drug that has side effects is poisonous and not healthful. See 1861.. ...
This drug is now known as arsphenamine.[101] The drug was used to treat syphilis in the first half of the 20th century. In 1908 ... "The introduction of chemotherapy using arsphenamine - the first magic bullet". Journal of the Royal Society of Medicine. 102 ...
03/31/1923 - "4. The method of gland transfers was used to test the sterilizing effect of arsphenamine and neoarsphenamine on ...
The value of sulphur-containing amino-acids and casein digest in the prevention of post-arsphenamine jaundice. BMJ 2: 651-655. ... The value of sulphur-containing amino-acids and casein digest in the prevention of post-arsphenamine jaundice. BMJ 2: 651-655. ...
p class=MsoNormal style=margin-bottom:.0001pt;line-height:normal;,Death following arsphenamine. Page.,/p,. ,p class= ...
Arsphenamine was marketed with the trade name of Salvarsan and was used to treat syphilis until the 1940s, when it was replaced ... The first of these was arsphenamine, which was developed in 1910 by the German medical scientist Paul Ehrlich for the treatment ... Arsphenamine was the 606th chemical studied by Ehrlich in his quest for an antisyphilitic drug. Its efficacy was first ... Arsphenamine was important not only because it was the first synthetic compound to kill a specific invading microorganism but ...
ON THE SPIROCHETICIDAL ACTION OF THE ARSPHENAMINES ON SPIROCHETA PALLIDA IN VITRO ...
With this new knowledge, Ehrlich tested Compound 606 (chemically arsphenamine) on a syphilis-infected rabbit. On 31 August 1909 ... Williams, K. (2009). "The introduction of chemotherapy using arsphenamine - the first magic bullet". Journal of the Royal ...
Williams KJ (2009). "The introduction of chemotherapy using arsphenamine - the first magic bullet". J R Soc Med. 102 (8): 343 ...
Interestingly enough, a revised structure of arsphenamine was published in 2005 (Lloyd et al., 2005). The story of arsphenamine ... The story of arsphenamine illustrates the value of both pharmacology and drug metabolism. Ehrlich established a system of ... Although arsphenamine had been the initial chemotherapeutic example of drug activation, the sulfanilamides had much greater ... The in vivo activity was later explained by Voegtlin and Smith when they determined that arsphenamine is actually a prodrug ...
At the time of the outbreak of World War I, the only effective treatments for syphilis were based on arsphenamine which was ... As early as March, 1916 the Research Institute was supplying arsphenamine to all 48 states and to the military. In Nov of 1917 ... Early in the war the Research Institute developed a process for the manufacture of arsphenamine. By early 1916, the supply of ...
Examples are quinine (q. v.), used against malaria; arsphenamine, used against syphilis; the sulfa drugs (q.v.) , used against ...
The company Farbwerke Hoechst marketed arsphenamine as the drug Salvarsan, "the arsenic that saves". Its specificity of action ... Ehrlich and Bertheims 606th arsenobenzene, synthesized in 1907, was arsphenamine, found ineffective against trypanosomes, but ...
The number 606 would become the slang name for the treatment with Salvarsan, the trade name for arsphenamine. Born: Ferenc ... Paul Ehrlich found the first successful treatment for syphilis, arsphenamine, on his 606th experiment. The compound, based on ...
  • Poisoning may also result from prolonged treatment with such medications as Fowler's solution (potassium arsenate) and arsphenamine. (britannica.com)