RNA, Transfer, Arg: A transfer RNA which is specific for carrying arginine to sites on the ribosomes in preparation for protein synthesis.RNA Ligase (ATP): An enzyme that catalyzes the conversion of linear RNA to a circular form by the transfer of the 5'-phosphate to the 3'-hydroxyl terminus. It also catalyzes the covalent joining of two polyribonucleotides in phosphodiester linkage. EC 6.5.1.3.Anticodon: The sequential set of three nucleotides in TRANSFER RNA that interacts with its complement in MESSENGER RNA, the CODON, during translation in the ribosome.Polynucleotide Ligases: Catalyze the joining of preformed ribonucleotides or deoxyribonucleotides in phosphodiester linkage during genetic processes. EC 6.5.1.Polynucleotide 5'-Hydroxyl-Kinase: An enzyme that catalyzes the transfer of a phosphate group to the 5'-terminal hydroxyl groups of DNA and RNA. EC 2.7.1.78.RNA, Transfer: The small RNA molecules, 73-80 nucleotides long, that function during translation (TRANSLATION, GENETIC) to align AMINO ACIDS at the RIBOSOMES in a sequence determined by the mRNA (RNA, MESSENGER). There are about 30 different transfer RNAs. Each recognizes a specific CODON set on the mRNA through its own ANTICODON and as aminoacyl tRNAs (RNA, TRANSFER, AMINO ACYL), each carries a specific amino acid to the ribosome to add to the elongating peptide chains.Amino Acyl-tRNA Synthetases: A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS.RNA Splicing: The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm.Basic-Leucine Zipper Transcription Factors: A large superfamily of transcription factors that contain a region rich in BASIC AMINO ACID residues followed by a LEUCINE ZIPPER domain.Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.tRNA Methyltransferases: Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Ubiquitin-Protein Ligases: A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.DNA Ligases: Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).Arginine Kinase: An enzyme that catalyzes the phosphorylation of the guanidine nitrogen of arginine in the presence of ATP and a divalent cation with formation of phosphorylarginine and ADP. EC 2.7.3.3.Arginine Vasopressin: The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.RNA, Transfer, Amino Acid-Specific: A group of transfer RNAs which are specific for carrying each one of the 20 amino acids to the ribosome in preparation for protein synthesis.RNA, Transfer, Amino Acyl: Intermediates in protein biosynthesis. The compounds are formed from amino acids, ATP and transfer RNA, a reaction catalyzed by aminoacyl tRNA synthetase. They are key compounds in the genetic translation process.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Nucleic Acid Conformation: The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.RNA, Transfer, Ser: A transfer RNA which is specific for carrying serine to sites on the ribosomes in preparation for protein synthesis.Ubiquitination: The act of ligating UBIQUITINS to PROTEINS to form ubiquitin-protein ligase complexes to label proteins for transport to the PROTEASOME ENDOPEPTIDASE COMPLEX where proteolysis occurs.RNA, Transfer, Phe: A transfer RNA which is specific for carrying phenylalanine to sites on the ribosomes in preparation for protein synthesis.Ubiquitin-Protein Ligase Complexes: Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES).Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.RNA, Transfer, Trp: A transfer RNA which is specific for carrying tryptophan to sites on the ribosomes in preparation for protein synthesis.Thermococcales: An order of strictly anaerobic, thermophilic archaea, in the kingdom EURYARCHAEOTA. Members exhibit heterotropic growth by sulfur respiration. There is a single family THERMOCOCCACEAE.Pyrococcus: A genus of strictly anaerobic ultrathermophilic archaea, in the family THERMOCOCCACEAE, occurring in heated seawaters. They exhibit heterotrophic growth at an optimum temperature of 100 degrees C.Arginine-tRNA Ligase: An enzyme that activates arginine with its specific transfer RNA. EC 6.1.1.19.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.Aggrecans: Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They form into aggregates that provide tissues with the capacity to resist high compressive and tensile forces.Nematoda: A class of unsegmented helminths with fundamental bilateral symmetry and secondary triradiate symmetry of the oral and esophageal structures. Many species are parasites.Peptide Termination Factors: Proteins that are involved in the peptide chain termination reaction (PEPTIDE CHAIN TERMINATION, TRANSLATIONAL) on RIBOSOMES. They include codon-specific class-I release factors, which recognize stop signals (TERMINATOR CODON) in the MESSENGER RNA; and codon-nonspecific class-II release factors.Pseudomonas stutzeri: A species of gram-negative bacteria in the genus PSEUDOMONAS, containing multiple genomovars. It is distinguishable from other pseudomonad species by its ability to use MALTOSE and STARCH as sole carbon and energy sources. It can degrade ENVIRONMENTAL POLLUTANTS and has been used as a model organism to study denitrification.Pseudomonas: A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.Pseudomonas aeruginosa: A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.Structural Homology, Protein: The degree of 3-dimensional shape similarity between proteins. It can be an indication of distant AMINO ACID SEQUENCE HOMOLOGY and used for rational DRUG DESIGN.Templates, Genetic: Macromolecular molds for the synthesis of complementary macromolecules, as in DNA REPLICATION; GENETIC TRANSCRIPTION of DNA to RNA, and GENETIC TRANSLATION of RNA into POLYPEPTIDES.Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.Methionine-tRNA Ligase: An enzyme that activates methionine with its specific transfer RNA. EC 6.1.1.10.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Sequence Analysis, Protein: A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.Systems Integration: The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Glutamate-Ammonia Ligase: An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene-L-glutamate. (From Enzyme Nomenclature, 1992) EC 6.3.1.2.Phenylglyoxal: A reagent that is highly selective for the modification of arginyl residues. It is used to selectively inhibit various enzymes and acts as an energy transfer inhibitor in photophosphorylation.Isoleucine-tRNA Ligase: An enzyme that activates isoleucine with its specific transfer RNA. EC 6.1.1.5.Tyrosine-tRNA Ligase: An enzyme that activates tyrosine with its specific transfer RNA. EC 6.1.1.1.Alanine-tRNA Ligase: An enzyme that activates alanine with its specific transfer RNA. EC 6.1.1.7.

tRNA synthetase mutants of Escherichia coli K-12 are resistant to the gyrase inhibitor novobiocin. (1/72)

In previous studies we demonstrated that mutations in the genes cysB, cysE, and cls (nov) affect resistance of Escherichia coli to novobiocin (J. Rakonjac, M. Milic, and D. J. Savic, Mol. Gen. Genet. 228:307-311, 1991; R. Ivanisevic, M. Milic, D. Ajdic, J. Rakonjac, and D. J. Savic, J. Bacteriol. 177:1766-1771, 1995). In this work we expand this list with mutations in rpoN (the gene for RNA polymerase subunit sigma54) and the tRNA synthetase genes alaS, argS, ileS, and leuS. Similarly to resistance to the penicillin antibiotic mecillinam, resistance to novobiocin of tRNA synthetase mutants appears to depend upon the RelA-mediated stringent response. However, at this point the overlapping pathways of mecillinam and novobiocin resistance diverge. Under conditions of stringent response induction, either by the presence of tRNA synthetase mutations or by constitutive production of RelA protein, inactivation of the cls gene diminishes resistance to novobiocin but not to mecillinam.  (+info)

Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase. (2/72)

Endothelial monocyte activating polypeptide II (EMAPII) is a cytokine that is specifically induced by apoptosis. Its precursor (pro-EMAPII) has been suggested to be identical to p43, which is associated with the multi-tRNA synthetase complex. Herein, we have demonstrated that the N-terminal domain of pro-EMAPII interacts with the N-terminal extension of human cytoplasmic arginyl-tRNA synthetase (RRS) using genetic and immunoprecipitation analyses. Aminoacylation activity of RRS was enhanced about 2.5-fold by the interaction with pro-EMAPII but not with its N- or C-terminal domains alone. The N-terminal extension of RRS was not required for enzyme activity but did mediate activity stimulation by pro-EMAPII. Pro-EMAPII reduced the apparent Km of RRS to tRNA, whereas the kcat value remained unchanged. Therefore, the precursor of EMAPII is a multi-functional protein that assists aminoacylation in normal cells and releases the functional cytokine upon apoptosis.  (+info)

In vivo selection of lethal mutations reveals two functional domains in arginyl-tRNA synthetase. (3/72)

Using random mutagenesis and a genetic screening in yeast, we isolated 26 mutations that inactivate Saccharomyces cerevisiae arginyl-tRNA synthetase (ArgRS). The mutations were identified and the kinetic parameters of the corresponding proteins were tested after purification of the expression products in Escherichia coli. The effects were interpreted in the light of the crystal structure of ArgRS. Eighteen functional residues were found around the arginine-binding pocket and eight others in the carboxy-terminal domain of the enzyme. Mutations of these residues all act by strongly impairing the rates of tRNA charging and arginine activation. Thus, ArgRS and tRNA(Arg) can be considered as a kind of ribonucleoprotein, where the tRNA, before being charged, is acting as a cofactor that activates the enzyme. Furthermore, by using different tRNA(Arg) isoacceptors and heterologous tRNA(Asp), we highlighted the crucial role of several residues of the carboxy-terminal domain in tRNA recognition and discrimination.  (+info)

Active aminoacyl-tRNA synthetases are present in nuclei as a high molecular weight multienzyme complex. (4/72)

Recent studies suggest that aminoacylation of tRNA may play an important role in the transport of these molecules from the nucleus to the cytoplasm. However, there is almost no information regarding the status of active aminoacyl-tRNA synthetases within the nuclei of eukaryotic cells. Here we show that at least 13 active aminoacyl-tRNA synthetases are present in purified nuclei of both Chinese hamster ovary and rabbit kidney cells, although their steady-state levels represent only a small percentage of those found in the cytoplasm. Most interestingly, all the nuclear aminoacyl-tRNA synthetases examined can be isolated as part of a multienzyme complex that is more stable, and consequently larger, than the comparable complex isolated from the cytoplasm. These data directly demonstrate the presence of active aminoacyl-tRNA synthetases in mammalian cell nuclei. Moreover, their unexpected structural organization raises important questions about the functional significance of these multienzyme complexes and whether they might play a more direct role in nuclear to cytoplasmic transport of tRNAs.  (+info)

Effect of sodium bisulfite modification on the arginine acceptance of E. coli tRNA Arg. (5/72)

Escherichia coli tRNA Arg was treated with sodium bisulfite to convert exposed cytosine residues to uracil. This treatment resulted in the loss of amino acid acceptance of the tRNA Arg with pseudo first-order reaction kinetics. The active and inactive molecules were separated after about 60e active and inactive molecules were separated after about 60 percent inactivation and analyzed for U in various positions by finger-printing of the oligonucleotides produced by nucleases. The results show that C to U base transitions in the dihydrouridine loop and in the CCA terminus have no effect on the aminoacylation of this tRNA. Deamination of a cytosine residue at the second position of the anticodon resulted in the loss of amino acid acceptor activity of arginine transfer RNA.  (+info)

Studies on arginyl-tRNA synthetase from Escherichia coli B. Dual role of metals in enzyme catalysis. (6/72)

Studies carried out in arginyl-tRNA synthetase from Escherichia coli indicate that metals may have two functional roles in the catalytic mechanism. Complete metal activation is observed when MgCl2, MnCl2, CoCl2, or FeCl2 is present at a concentration (5.0 mM) in excess of the total ATP concentration (2.0 mM). When CaCl2 is substituted for MgCl2, activity is not observed unless a small amount (0.1 mM) of MgCl2, MnCl2, CoCl2, FeCl2, or ZnCl2 (unable to produce activity alone at 5.0 mM) is added. A model, based on kinetic data, is proposed in which the enzyme possesses a site for free metal, which, when filled, lowers the Km for all three substrates (arginine, tRNAArg, and metal-ATP) and increases the Vmax of the reaction.  (+info)

tRNA aminoacylation by arginyl-tRNA synthetase: induced conformations during substrates binding. (7/72)

The 2.2 A crystal structure of a ternary complex formed by yeast arginyl-tRNA synthetase and its cognate tRNA(Arg) in the presence of the L-arginine substrate highlights new atomic features used for specific substrate recognition. This first example of an active complex formed by a class Ia aminoacyl-tRNA synthetase and its natural cognate tRNA illustrates additional strategies used for specific tRNA selection. The enzyme specifically recognizes the D-loop and the anticodon of the tRNA, and the mutually induced fit produces a conformation of the anticodon loop never seen before. Moreover, the anticodon binding triggers conformational changes in the catalytic center of the protein. The comparison with the 2.9 A structure of a binary complex formed by yeast arginyl-tRNA synthetase and tRNA(Arg) reveals that L-arginine binding controls the correct positioning of the CCA end of the tRNA(Arg). Important structural changes induced by substrate binding are observed in the enzyme. Several key residues of the active site play multiple roles in the catalytic pathway and thus highlight the structural dynamics of the aminoacylation reaction.  (+info)

Crucial role of the high-loop lysine for the catalytic activity of arginyl-tRNA synthetase. (8/72)

The presence of two short signature sequence motifs (His-Ile-Gly-His (HIGH) and Lys-Met-Ser-Lys (KMSK)) is a characteristic of the class I aminoacyl-tRNA synthetases. These motifs constitute a portion of the catalytic site in three dimensions and play an important role in catalysis. In particular, the second lysine of the KMSK motif (K2) is the crucial catalytic residue for stabilization of the transition state of the amino acid activation reaction (aminoacyl-adenylate formation). Arginyl-tRNA synthetase (ArgRS) is unique among all of the class I enyzmes, as the majority of ArgRS species lack canonical KMSK sequences. Thus, the mechanism by which this group of ArgRSs achieves the catalytic reaction is not well understood. Using three-dimensional modeling in combination with sequence analysis and site-directed mutagenesis, we found a conserved lysine in the KMSK-lacking ArgRSs upstream of the HIGH sequence motif, which is likely to be a functional counterpart of the canonical class I K2 lysine. The results suggest a plausible partition of the ArgRSs into two major groups, on the basis of the conservation of the HIGH lysine.  (+info)

The SCOP classification for the Arginyl-tRNA synthetase (ArgRS), N-terminal additional domain superfamily including the families contained in it. Additional information provided includes InterPro annotation (if available), Functional annotation, and SUPERFAMILY links to genome assignments, alignments, domain combinations, taxonomic visualisation and hidden Markov model information.
SWISS-MODEL Template Library (SMTL) entry for 5b63.1. Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg)
... BSD System Managers Manual CAMCONTROL(8) NAME camcontrol -- CAM control program SYNOPSIS camcontrol ,command, [device id] [generic args] [command args] camcontrol devlist [-v] camcontrol periphlist [device id] [-n dev_name] [-u unit_number] camcontrol tur [device id] [generic args] camcontrol inquiry [device id] [generic args] [-D] [-S] [-R] camcontrol start [device id] [generic args] camcontrol stop [device id] [generic args] camcontrol load [device id] [generic args] camcontrol eject [device id] [generic args] camcontrol rescan ,all , bus[:target:lun], camcontrol reset ,all , bus[:target:lun], camcontrol defects [device id] [generic args] ,-f format, [-P] [-G] camcontrol modepage [device id] [generic args] ,-m page , -l, [-P pgctl] [-b , -e] [-d] camcontrol cmd [device id] [generic args] ,-c cmd [args], [-i len fmt] [-o len fmt [args]] camcontrol debug [-I] [-P] [-T] [-S] [-X] [-c] ,all,off,bus[:target[:lun]], camcontrol tags [device id] [generic args] [-N tags] [-q] [-v] ...
swig_c++.tcl # Provides a simple object oriented interface using # SWIGs low level interface. # proc new {objectType handle_r args} { # Creates a new SWIG object of the given type, # returning a handle in the variable "handle_r". # # Also creates a procedure for the object and a trace on # the handle variable that deletes the object when the # handle variable is overwritten or unset upvar $handle_r handle # # Create the new object # eval set handle \[new_$objectType $args\] # # Set up the object procedure # proc $handle {cmd args} "eval ${objectType}_\$cmd $handle \$args" # # And the trace ... # uplevel trace variable $handle_r uw "{deleteObject $objectType $handle}" # # Return the handle so that new can be used as an argument to a procedure # return $handle } proc deleteObject {objectType handle name element op} { # # Check that the object handle has a reasonable form # if {![regexp {_[0-9a-f]*_(.+)_p} $handle]} { error "deleteObject: not a valid object handle: $handle" } # # Remove the ...
I got args halfway into my season and i only got to ride them five times or so, since i do not have a place in the mountains i feel like this may be just to muc
mikelove: trying out: alias rhelp="Rscript -e args ,- commandArgs(TRUE); help(args[2], package=args[3], help_type=html); Sys.sleep(5) --args" (5 Aug ...
11:05:18] ,Darke, So far every file has been named by the primary class inside it, so Args.cc,h has a class Args { definition, etc. The problem is what to do with files that lack class? Ive got the holdover from exult common_types.h, now logically I should rename it to CommonTypes.hpp, just because its the same capitalisation as the other files. But it doesnt contain a CommonTypes class ...
File lib/spec/example/example_group_factory.rb, line 23 def create_shared_example_group(*args, &example_group_block) # :nodoc: ::Spec::Example::SharedExampleGroup.register(*args, &example_group_block) end ...
File lib/spec/example/shared_example_group.rb, line 49 def initialize(*args, &example_group_block) set_description(*args) @example_group_block = example_group_block end ...
I was so disappointed last night! First, I was shocked that there was no clear plan of action given to Raelyn by her doctor. Was she ever even tested for food allergies? Yes, I know her dx, but perhaps if she were tested she would know some of her definitive triggers. Everytime I saw her eat gluten and dairy I would cringe, knowing what was coming. Also, that chiropractor didnt tell her to start food challenges, he said she still needed to wait. (I know there is no cure, Im just saying...lets not blame the chiro here) the family and herself made an irresponsible choice and did not do a proper food challenge. As for Zeke, those food challenges were crazy! A food challenge should not consist of that much food. His mom was complaining about the few extra carrots he snuck in at the office, but at home gave him 4-5 tuna steaks. That is a bit excessive. I felt that these parents didnt have the proper guidance and were just winging it as best they could. They need the help of these blogs and ...
TSEN54-related pontocerebellar hypoplasia (PCH) includes three PCH types (PCH2, 4, and 5) that share characteristic neuroradiologic and neurologic findings. The three types (which differ mainly in life expectancy) were thought to be distinct entities before their molecular basis was known. Children with PCH2 usually succumb before age ten years, whereas those with PCH4 and 5 usually succumb as neonates. Children with PCH2 have generalized clonus, incoordination of sucking and swallowing, impaired motor and cognitive development with lack of voluntary motor development, central visual impairment, and an increased risk for rhabdomyolysis complicating severe infections. Epilepsy is present in approximately 50%. Neonates with PCH4 often have seizures, multiple joint contractures (arthrogryposis), generalized clonus, and central respiratory impairment. PCH5, which resembles PCH4, has been described in one family.
ID SYR_LISW6 Reviewed; 556 AA. AC A0ALP7; DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot. DT 28-NOV-2006, sequence version 1. DT 20-DEC-2017, entry version 72. DE RecName: Full=Arginine--tRNA ligase {ECO:0000255,HAMAP-Rule:MF_00123}; DE EC=6.1.1.19 {ECO:0000255,HAMAP-Rule:MF_00123}; DE AltName: Full=Arginyl-tRNA synthetase {ECO:0000255,HAMAP-Rule:MF_00123}; DE Short=ArgRS {ECO:0000255,HAMAP-Rule:MF_00123}; GN Name=argS {ECO:0000255,HAMAP-Rule:MF_00123}; GN OrderedLocusNames=lwe2511; OS Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / OS SLCC5334). OC Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria. OX NCBI_TaxID=386043; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 35897 / DSM 20650 / SLCC5334; RX PubMed=16936040; DOI=10.1128/JB.00758-06; RA Hain T., Steinweg C., Kuenne C.T., Billion A., Ghai R., RA Chatterjee S.S., Domann E., Kaerst U., Goesmann A., Bekel T., RA Bartels D., Kaiser O., Meyer F., Puehler A., Weisshaar B., Wehland ...
The intracellular distribution of various components of the protein translational machinery was visualized in mouse oligodendrocytes in culture using high resolution fluorescence in situ hybridization and immunofluorescence in conjunction with dual channel confocal laser scanning microscopy. Arginyl-tRNA synthetase, elongation factor 1a, ribosomal RNA, and myelin basic protein mRNA were all co-localized in granules in the processes, veins and membrane sheets of the cell. Colocalization was evaluated by dual channel cross correlation analysis to determine the correlation index (% colocalization) and correlation distance (granule radius), and by single granule ratiometric analysis to determine the distribution of the different components in individual granules. Most granules contained synthetase, elongation factor, ribosomal RNA and myelin basic protein mRNA. These results indicate that several different components of the protein synthetic machinery, including aminoacyl-tRNA synthetases, ...
Order TSEN2 ELISA Kits for many Reactivities. and more. Compare TSEN2 ELISA Kits and find the right product on antibodies-online.com.
src/Elasticsearch/Query/QueryBuilder.php public function addFilter(\Elastica\Query\AbstractQuery $filter) public function addPostFilter(\Elastica\Query\AbstractQuery $postFilter) ./src/Elasticsearch/Provider/Visibility/StrategyInterface.php public function elasticAddFilters(User $user, \Elastica\Query\BoolQuery $filter, Visibility $provider); ./clients/base/api/BulkApi.php public function bulkCall(ServiceBase $api, array $args) ./clients/base/api/CalendarEventsApi.php public function updateCalendarEvent(ServiceBase $api, array $args) public function deleteCalendarEvent(ServiceBase $api, array $args) public function updateRecurringCalendarEvent(SugarBean $bean, ServiceBase $api, array &$args) public function deleteRecordAndRecurrences(ServiceBase $api, array $args) public function deleteRecurrences(SugarBean $bean) protected function initializeArgs(array $args, SugarBean $bean = null) protected function adjustStartDate(array &$args) protected function filterOutRecurrenceFields(array $args) ...
Complete information for TSEN2 gene (Protein Coding), TRNA Splicing Endonuclease Subunit 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Is there a way to have a metaclass similar to our ClasscallMetaclass at all, in Python3?? I just tested, having class Classcall(type): def __call__(cls, *args, **opts): try: classcall = cls.__classcall__ except AttributeError: return type.__call__(cls, *args, **opts) return classcall(cls, *args, **opts) class MyUniqueRepresentation: __metaclass__ = Classcall @staticmethod def __classcall__(cls, *args, **opts): out = super(cls,cls).__new__(cls, *args, **opts) print(classcall got,type(out), cls) cls.__init__(out,*args,**opts) out._reduction = (type(out), args, opts) return out Loading the above into python2, I get ,,, class Foo(MyUniqueRepresentation): ... def __init__(self, a,b): ... self.a = a ... self.b = b ... ,,, A = Foo(A,B) (classcall got, ,class __main__.Foo,, ,class __main__.Foo,) ,,, A._reduction (,class __main__.Foo,, (A, B), {}) But doing the same in python3, it gives ,,, class Foo(MyUniqueRepresentation): ... def __init__(self, a,b): ... self.a = a ... self.b = b ... ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Large search returns make our pages slow to load. Therefore, some functionality has been disabled until you refine your search to bring the number of returned assay results under TBD ...
Large search returns make our pages slow to load. Therefore, some functionality has been disabled until you refine your search to bring the number of returned assay results under TBD ...
usr/bin/env desres-exec #{ # exec desres-cleanenv -c --user-env \ # -m Python/2.7.1-06A/bin \ # -m destro/0.6.2/lib-python \ # -m scipy/0.12.0-01/lib-python \ # -m destiny/0.4.47-3/lib-python \ # -m molpro/2012.1.12-desres-3-02/serial/bin \ # -m psi4/4.0b5-desres-2-01/bin \ # -- python -u $0 [email protected] #} import sys sys.path.append(/u/en/donchev/pyprogs) sys.path.append(/u/en/donchev/pyprogs/chemsys) sys.path.append(/d/en/ffdevel-0/bin/pyqmdata) sys.path.append(/u/en/donchev/playground/qmdata6/) import math, numpy import subprocess import time import copy import string import units import prepmpr import pth4 as pth import frame import class_qmjob import class_scannmer class MultiScanNmer(object): def __init__(self, finput, opts, molpro_args=[]): self.molpro_args = molpro_args self.opts = opts #self.basopt = self.opts.basopt #self.basene = self.opts.basene #self.basesl = self.opts.basesl self.ncores = self.opts.ncores self.verbose = self.opts.verbose self.rerun = self.opts.rerun self.pinput = ...
from genshi.core import Markup from trac.wiki.macros import WikiMacroBase class HelloWorldMacro(WikiMacroBase): """Simple HelloWorld macro. Note that the name of the class is meaningful: - it must end with "Macro" - what comes before "Macro" ends up being the macro name The documentation of the class (i.e. what youre reading) will become the documentation of the macro, as shown by the !MacroList macro (usually used in the WikiMacros page). """ revision = "$Rev$" url = "$URL$" def expand_macro(self, formatter, name, text, args): """Return some output that will be displayed in the Wiki content. `name` is the actual name of the macro (no surprise, here itll be `HelloWorld`), `text` is the text enclosed in parenthesis at the call of the macro. Note that if there are no parenthesis (like in, e.g. [[HelloWorld]]), then `text` is `None`. `args` are the arguments passed when HelloWorld is called using a `#!HelloWorld` code block. """ return Hello World, text = %s, args = %s % \ ...
from genshi.core import Markup from trac.wiki.macros import WikiMacroBase class HelloWorldMacro(WikiMacroBase): """Simple HelloWorld macro. Note that the name of the class is meaningful: - it must end with "Macro" - what comes before "Macro" ends up being the macro name The documentation of the class (i.e. what youre reading) will become the documentation of the macro, as shown by the !MacroList macro (usually used in the WikiMacros page). """ revision = "$Rev$" url = "$URL$" def expand_macro(self, formatter, name, text, args): """Return some output that will be displayed in the Wiki content. `name` is the actual name of the macro (no surprise, here itll be `HelloWorld`), `text` is the text enclosed in parenthesis at the call of the macro. Note that if there are no parenthesis (like in, e.g. [[HelloWorld]]), then `text` is `None`. `args` are the arguments passed when HelloWorld is called using a `#!HelloWorld` code block. """ return Hello World, text = %s, args = %s % \ ...
O esperado é algo assim? [09-Nov-2017 04:51:35 UTC] hook http_request_args: 1510203095 [09-Nov-2017 04:51:46 UTC] hook… 2 months ago. ...
Looking for online definition of pontocerebellar hypoplasia type 2A in the Medical Dictionary? pontocerebellar hypoplasia type 2A explanation free. What is pontocerebellar hypoplasia type 2A? Meaning of pontocerebellar hypoplasia type 2A medical term. What does pontocerebellar hypoplasia type 2A mean?
Rajab et al. (2003) reported the clinical features of three affected children born to consanguineous Omani parents with a novel form of pontocerebellar hypoplasia with microcephaly, and conducted genetic studies to identify the genetic locus of this disorder. The first case was a 12-year old boy, born with occipito-frontal circumference (OFC), length, and weight in the 10th percentile. During infancy, he was floppy, not interested in his surroundings, had motor developmental delay as he had no head control, did not roll over or sit, and had a history of recurrent respiratory tract infection. By the age of eight months, his anterior fontanelles were closed and fundoscopic examination revealed pale optic discs. He developed generalized tonic clonic seizures after an episode of febrile convulsions at one year of age, and was on sodium valoproate. Clinically, he had microcephaly (OFC was 45 cm, increased by 5 cm only since he was 18 months), was below the third percentile in weight and height, ...
Minuscule event, far-reaching consequences. During the time of the Ottoman Empire, one person experienced a single mutation in a certain gene. Centuries later, children descended from that unknown individual still suffer the consequences: a deadly form of degeneration of the brain that is called pontocerebellar hypoplasia (PCH).. The mutation was discovered by Yale genetics, neurosurgery, and neurobiology professor Murat Günel 94Grd, working with researchers in Turkey and several other countries. PCH is a collection of disorders caused by various genetic mishaps. But this mutation and the surrounding genomic areas were identical in the affected patients, who came from four families with a history of intermarriage. The researchers deduced, from the nature of the mutation, that all of the children share a common ancestor who lived roughly 16 generations ago. The findings appeared in the April 24 issue of Cell.. Specific mutations can tell us a lot about normal function; this one, the researchers ...
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In the project root set the following alias $: alias render=mvn exec:java -Dexec.mainClass=Main # Using OPSIN to load porphyrin and generate a PDF $: render -Dexec.args="-name porphyrin -pdf" # Highlight one of the pyrrole in porphyrin $: render -Dexec.args="-name porphyrin -pdf -sma n1cccc1" # Show atom numbers $: render -Dexec.args="-name porphyrin -pdf -atom-numbers" # Show CIP labels $: render -Dexec.args="-name (2R)-butan-2-ol -pdf -cip-labels" # Generate a PDF / SVG for ethanol SMILES $: render -Dexec.args="-smi CCO -pdf ethanol.pdf -svg ethanol.svg" # Load a molfile $: render -Dexec.args="-mol ChEBI_6701.mol -pdf chebi-6701.pdf ...
In the project root set the following alias $: alias render=mvn exec:java -Dexec.mainClass=Main # Using OPSIN to load porphyrin and generate a PDF $: render -Dexec.args="-name porphyrin -pdf" # Highlight one of the pyrrole in porphyrin $: render -Dexec.args="-name porphyrin -pdf -sma n1cccc1" # Show atom numbers $: render -Dexec.args="-name porphyrin -pdf -atom-numbers" # Show CIP labels $: render -Dexec.args="-name (2R)-butan-2-ol -pdf -cip-labels" # Generate a PDF / SVG for ethanol SMILES $: render -Dexec.args="-smi CCO -pdf ethanol.pdf -svg ethanol.svg" # Load a molfile $: render -Dexec.args="-mol ChEBI_6701.mol -pdf chebi-6701.pdf ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
This graph shows the total number of publications written about "Canavanine" by people in this website by year, and whether "Canavanine" was a major or minor topic of these publications ...
We just purchased a solar cover for our pool after mice destroyed the one we stored for the winter in my moms shed. We have a free form pool so I purchased a rectangular shaped cover and plan to trim. We laid it out over the pool for three days and then did a rough trim. I could have sworn that I read somewhere that you should let your cover sit for two weeks before doing a final fitted trim but now I cannot find that. Does anyone know if that is the case or are we ok to go ahead and do
sys_var (sys_var_chain *chain, const char *name_arg, const char *comment, int flag_args, ptrdiff_t off, int getopt_id, enum get_opt_arg_type getopt_arg_type, SHOW_TYPE show_val_type_arg, longlong def_val, PolyLock *lock, enum binlog_status_enum binlog_status_arg, on_check_function on_check_func, on_update_function on_update_func, const char *substitute, int parse_flag ...
Anybody ever use this function? It looks like exactly what I need. Im trying to get the content of a couple of resources into fred windows. In classic style, there is no documentation and C-x C-a says the args are named arg-1 arg-2 &key key-1 key-2 key-3 key-4 key-5. Maybe they figure what we dont know cant hurt us? Blake Meike [email protected] ...
Title : seqname Usage : $obj-,seq_id($newval) Function: There are many cases when you make a feature that you do know the sequence name, but do not know its actual sequence. This is an attribute such that you can store the seqname. This attribute should *not* be used in GFF dumping, as that should come from the collection in which the seq feature was found. Returns : value of seqname Args : newvalue (optional ...
At least 16 mutations in the EXOSC3 gene have been identified in people with a disorder of brain development called pontocerebellar hypoplasia. The major features of this condition include delayed development overall, an unusually small head size (microcephaly), and intellectual disability. EXOSC3 gene mutations cause about half of all cases of a form of the disorder designated pontocerebellar hypoplasia type 1 (PCH1). When PCH1 results from EXOSC3 gene mutations, it is sometimes categorized more specifically as PCH1B. In addition to the features listed above, PCH1B causes problems with muscle movement resulting from a loss of specialized nerve cells called motor neurons in the spinal cord.. The EXOSC3 gene mutations that cause PCH1B result in an exosome component 3 protein with reduced or no function. The most common mutation alters a single protein building block (amino acid) in exosome component 3; it replaces the amino acid aspartic acid with the amino acid alanine at protein position 132 ...
From UniProt:. Spastic paraplegia 63, autosomal recessive (SPG63): A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. [MIM:615686]. Pontocerebellar hypoplasia 9 (PCH9): A form of pontocerebellar hypoplasia, a disorder characterized by structural defects of the pons and cerebellum, evident upon brain imaging. PCH9 features include severely delayed psychomotor development, progressive microcephaly, spasticity, seizures, and brain abnormalities, including brain atrophy, thin corpus callosum, and delayed myelination. [MIM:615809]. ...
Rabbit monoclonal antibody raised against a human TSEN15 peptide using ARM Technology. A synthetic peptide of human TSEN15 is used for rabbit immunization.Customer or Abnova will decide on the preferred peptide sequence. (H00116461-K) - Products - Abnova
hellogtk.c generated by valac 0.34.4, the Vala compiler * generated from hellogtk.vala, do not modify */ #include ,glib.h, #include ,glib-object.h, #include ,stdlib.h, #include ,string.h, #include ,gtk/gtk.h, #define _g_object_unref0(var) ((var == NULL) ? NULL : (var = (g_object_unref (var), NULL))) gint _vala_main (gchar** args, int args_length1); static void _gtk_main_quit_gtk_widget_destroy (GtkWidget* _sender, gpointer self); static void _gtk_main_quit_gtk_widget_destroy (GtkWidget* _sender, gpointer self) { gtk_main_quit (); } gint _vala_main (gchar** args, int args_length1) { gint result = 0; GtkWindow* window = NULL; GtkWindow* _tmp0_ = NULL; GtkLabel* label = NULL; GtkLabel* _tmp1_ = NULL; gtk_init (&args_length1, &args); _tmp0_ = (GtkWindow*) gtk_window_new (GTK_WINDOW_TOPLEVEL); g_object_ref_sink (_tmp0_); window = _tmp0_; gtk_window_set_title (window, "Hello, World!"); gtk_container_set_border_width ((GtkContainer*) window, (guint) 10); g_object_set (window, "window-position", ...
Use Bio-Rads PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed.
Use Bio-Rads PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed.
The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _ id Title : id Usage : $obj-,id(3); $id_integer = $obj-,id(); Function: Sets or returns the id of the translation table. IDs are integers from 0 (special ATG-only start) to 25, excluding 7-8 and 17-20 which have been removed. If an invalid ID is given the method returns 1, the standard table. Example : Returns : value of id, a scalar, warn and fall back to 1 (standard table) if specified id is not valid Args : newvalue (optional) name Title : name Usage : $obj-,name() Function: returns the descriptive name of the translation table Example : Returns : A string Args : None tables Title : tables Usage : $obj-,tables() or Bio::Tools::CodonTable-,tables() Function: returns a hash reference where each key is a valid codon table id() number, and each value is the corresponding codon table name() string Example : Returns : A hashref Args : None translate Title : translate Usage : ...
Nma-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DNP)-D-Arg-D-Arg-NH2 3229-v 1 mg | 135.00 EUR[2- (Methylamino)benzoyl]- L- isoleucyl- L- ...
class BubbleSort { public static void sort(int[] a) { int i; int j; for (i = 0 ; i , a.length; i++) { /* move the largest number up */ for (j = 0 ; j , a.length - i - 1; j++) { if (a[j] , a[j+1]) ArrayUtil.swap(a, j, j + 1); } } } } public class BubbleSortTest { public static void main(String[] args) { int[] a = ArrayUtil.randomIntArray(20, 100); ArrayUtil.print(a); BubbleSort.sort(a); ArrayUtil.print(a ...
1, post_type => kwlogos, post_status => publish, orderby => rand, taxonomy => kwlogos-carousel, term => banner); $banner=get_posts($args); $thumbnail_id = get_post_thumbnail_id($banner[0]->ID); $image = wp_get_attachment_image_src($thumbnail_id, full ...
Semantic Scholar extracted view of [14C]erythromycin-ribosome complex formation and non-enzymatic binding of aminoacyl-transfer RNA to ribosome-messenger RNA complex. by Kohichi Tanaka et al.
Alibaba.com offers 3,651 free form board products. About 12% of these are plastic sheets, 1% are plywoods, and 1% are sandwich panels. A wide variety of free form board options are available to you, such as first-class, st (standard).
Warning: Declaration of PLL_Walker_List::walk($elements, $args = Array) should be compatible with Walker::walk($elements, $max_depth, ...$args) in /home/hydrog63/public_html/wp-content/plugins/polylang/include/walker-list.php on line 0 ...
I was logged in when the first server went live and I had (still have, written down) a key to help open it, but got no message about a reward once I entered the key (and I realized after that that my MSN profile was empty of my address and personal info ...
A mozg st l nem maradunk v konyak. A t pl lkoz ssal foglalkoz k, akik annyira szorgalmazz k, hogy testmozg ssal fogyjunk, elfelejtik azt a t nyt, hogy min l t bb energi t haszn lunk el, ann l hesebbek lesz nk. K pzelje el, hogy felk rtem Alice Waters mesterszak csot, hogy n lam otthon k sz tsen el egy 12 fog sos lakom t, s nt is megh vtam. Felk rtem egy mestercukr szt s egy nyenc hentest is - tudniillik m r ilyen is van.. Val sz n leg k t dolgot fog tenni: aznap kihagyja az eb det s t bbet mozog. Esetleg m g azt is gondolja: Taubes nem eg szen t kilom ternyire lakik t lem, gyalog megyek oda, s mire oda rek, biztosan hes leszek. A vicc az, hogy az a k t dolog, amit a lefogyni v gy embereknek mondunk - vagyis, hogy egyenek kevesebbet s mozogjanak t bbet -, az pontosan megegyezik azzal a k t dologgal, amit mag t l rtet d n tesz nk, ha meg akarunk hezni.. Ha megn zz k az elh z sra s a testmozg sra vonatkoz kutat si eredm nyeket, nem tal lunk meggy z bizony t kot arra, hogy a mozg snak b rmilyen hat ...
***Problem****In this program if the frequency is large (say, 9) the frequency shows it as 9.000000000006. import java.io.*; public class Freq { public static void main(String args) { System.out.println(Type string : ); String str = ;
The pontocerebellar fibers are the second order neuron fibers of the corticopontocerebellar tracts that cross to the other side of the pons and run within the middle cerebellar peduncles, from the pons to the contralateral cerebellum. The term "corticopontocerebellar"[1] is the entire pathway from the cerebral cortex to the contralateral cerebellum.[2] ...
Case Reports in Emergency Medicine is a peer-reviewed, Open Access journal that publishes case reports in all areas of emergency medicine.
Looking for online definition of canavanine in the Medical Dictionary? canavanine explanation free. What is canavanine? Meaning of canavanine medical term. What does canavanine mean?
One of the most worrying things about the results is that the smog in Beijing contained a high level of ARGs which could grant resistance to carbapenems - antibiotics used as a last-resort against bacteria which are usually very difficult to treat. With these particular genes, such as IND, GES and IMP, circulating in the air, theres a higher likelihood that they could be spread around further, therefore increasing the number of these dangerous bacteria.. To see if air typically contains high levels of ARGs, the researchers followed this up by analysing indoor and outdoor air from two US cities, New York and San Diego. They found that while the air from both cities was comparable in terms of the presence of ARGs, samples from the smog in Beijing were much richer in resistance genes (though they noted that this difference wasnt so extreme when they analysed office indoor air samples).. Something the study couldnt determine was whether the bacteria that owned these ARGs in the samples collected ...
Callstack: at Proteins/JCSG/2raa at Template:Protein at Template:Pathway at tmdb.RecordList MindTouch.Deki.Script.Runtime.DekiScriptRemoteException: Access denied for user [email protected] (using password: YES) at MindTouch.Deki.Script.Runtime.TargetInvocation.DekiScriptRemoteInvocationTarget.InvokeList (MindTouch.Deki.Script.DekiScriptRuntime runtime, MindTouch.Deki.Script.Expr.DekiScriptList args) [0x00000] in ,filename unknown,:0 at MindTouch.Deki.Script.Runtime.TargetInvocation.ADekiScriptInvocationTarget.Invoke (MindTouch.Deki.Script.DekiScriptRuntime runtime, MindTouch.Deki.Script.Expr.DekiScriptLiteral args) [0x00000] in ,filename unknown,:0 at MindTouch.Deki.Script.DekiScriptRuntime.Invoke (Location location, MindTouch.Dream.XUri uri, MindTouch.Deki.Script.Expr.DekiScriptLiteral args, MindTouch.Deki.Script.Runtime.DekiScriptEnv env) [0x00000] in ,filename unknown,:0 ...
Callstack: at Proteins/MCSG/APC020 at Template:Protein at Template:Pathway at tmdb.RecordList MindTouch.Deki.Script.Runtime.DekiScriptRemoteException: Access denied for user [email protected] (using password: YES) at MindTouch.Deki.Script.Runtime.TargetInvocation.DekiScriptRemoteInvocationTarget.InvokeList (MindTouch.Deki.Script.DekiScriptRuntime runtime, MindTouch.Deki.Script.Expr.DekiScriptList args) [0x00000] in ,filename unknown,:0 at MindTouch.Deki.Script.Runtime.TargetInvocation.ADekiScriptInvocationTarget.Invoke (MindTouch.Deki.Script.DekiScriptRuntime runtime, MindTouch.Deki.Script.Expr.DekiScriptLiteral args) [0x00000] in ,filename unknown,:0 at MindTouch.Deki.Script.DekiScriptRuntime.Invoke (Location location, MindTouch.Dream.XUri uri, MindTouch.Deki.Script.Expr.DekiScriptLiteral args, MindTouch.Deki.Script.Runtime.DekiScriptEnv env) [0x00000] in ,filename unknown,:0 ...
Callstack: at Proteins/JCSG/282372 at Template:Protein at Template:Pathway at tmdb.RecordList MindTouch.Deki.Script.Runtime.DekiScriptRemoteException: Access denied for user [email protected] (using password: YES) at MindTouch.Deki.Script.Runtime.TargetInvocation.DekiScriptRemoteInvocationTarget.InvokeList (MindTouch.Deki.Script.DekiScriptRuntime runtime, MindTouch.Deki.Script.Expr.DekiScriptList args) [0x00000] in ,filename unknown,:0 at MindTouch.Deki.Script.Runtime.TargetInvocation.ADekiScriptInvocationTarget.Invoke (MindTouch.Deki.Script.DekiScriptRuntime runtime, MindTouch.Deki.Script.Expr.DekiScriptLiteral args) [0x00000] in ,filename unknown,:0 at MindTouch.Deki.Script.DekiScriptRuntime.Invoke (Location location, MindTouch.Dream.XUri uri, MindTouch.Deki.Script.Expr.DekiScriptLiteral args, MindTouch.Deki.Script.Runtime.DekiScriptEnv env) [0x00000] in ,filename unknown,:0 ...
req = $c-,request; $req-,action; $req-,address; $req-,arguments; $req-,args; $req-,base; $req-,body; $req-,body_parameters; $req-,content_encoding; $req-,content_length; $req-,content_type; $req-,cookie; $req-,cookies; $req-,header; $req-,headers; $req-,hostname; $req-,input; $req-,match; $req-,method; $req-,param; $req-,parameters; $req-,params; $req-,path; $req-,protocol; $req-,query_parameters; $req-,read; $req-,referer; $req-,secure; $req-,captures; # previously knows as snippets $req-,upload; $req-,uploads; $req-,uri; $req-,user; $req-,user_agent ...
Hello again Sorry I didnt make the problem Im working with all too clear. Basically Im working with a class (Directory) that upon creation reads in a 3 files and from these files populates one main list. This bit is fine. The trickier bit was that I need to use two of the sublists (e.g the contents of two of the files) outwith the module. I didnt want to read the lists in again as I wanted the data to be set at the time the Directory class is created. The lists are accessed from other classes and although I tried passing the instance of Directory into the new class (Item) but this was causing real problems Item was trying to read in the lists: def __init__(self, filename, **args): I noted that I couldnt put my argument for an instance of Directory after **args (presumably because **args is used to mop up the remaining arguments as a list) and when I put it before it messed up the reading of the list. So my code now has this format- def GetCategories(self): #Assign the list values read in ...
Re: [PATCH 1/6] selftests/clone3: convert test modes into an enum 2019-09-10 12:03 ` [PATCH 1/6] selftests/clone3: convert test modes into an enum Eugene Syromiatnikov @ 2019-09-16 16:28 ` shuah 0 siblings, 0 replies; 13+ messages in thread From: shuah @ 2019-09-16 16:28 UTC (permalink / raw) To: Eugene Syromiatnikov, linux-kernel, Christian Brauner, linux-kselftest Cc: Adrian Reber, shuah On 9/10/19 6:03 AM, Eugene Syromiatnikov wrote: , * tools/testing/selftests/clone3/clone3.c (CLONE3_ARGS_NO_TEST, , CLONE3_ARGS_ALL_0, CLONE3_ARGS_ALL_1): Change into an enum. , (call_clone3): Change test_mode parameter type to enum test_mode; , use switch statement for actions that dependent on test_mode selection. , (test_clone3): Change test_mode parameter type to enum test_mode. , You dont need the file name in the commit log. Please describe what you are fixing/doing in the commit. Describing the actual code changes doesnt help. Including why these changes are needed as opposed the actual changes will ...
BrianObjectExceptionTraceback (most recent call last) ,ipython-input-11-d086eea0b2de, in ,module,() 3 4 G = NeuronGroup(1, eqs) ----, 5 run(100*ms) /home/marcel/programming/brian2/brian2/units/fundamentalunits.pyc in new_f(*args, **kwds) 2353 get_dimensions(newkeyset[k])) 2354 -, 2355 result = f(*args, **kwds) 2356 if result in au: 2357 if au[result] == bool: /home/marcel/programming/brian2/brian2/core/magic.pyc in run(duration, report, report_period, namespace, profile, level) 369 370 return magic_network.run(duration, report=report, report_period=report_period, --, 371 namespace=namespace, profile=profile, level=2+level) 372 run.__module__ = __name__ 373 /home/marcel/programming/brian2/brian2/core/magic.pyc in run(self, duration, report, report_period, namespace, profile, level) 229 self._update_magic_objects(level=level+1) 230 Network.run(self, duration, report=report, report_period=report_period, --, 231 namespace=namespace, profile=profile, level=level+1) 232 233 def store(self, ...
BrianObjectExceptionTraceback (most recent call last) ,ipython-input-11-d086eea0b2de, in ,module,() 3 4 G = NeuronGroup(1, eqs) ----, 5 run(100*ms) /home/marcel/programming/brian2/brian2/units/fundamentalunits.pyc in new_f(*args, **kwds) 2353 get_dimensions(newkeyset[k])) 2354 -, 2355 result = f(*args, **kwds) 2356 if result in au: 2357 if au[result] == bool: /home/marcel/programming/brian2/brian2/core/magic.pyc in run(duration, report, report_period, namespace, profile, level) 369 370 return magic_network.run(duration, report=report, report_period=report_period, --, 371 namespace=namespace, profile=profile, level=2+level) 372 run.__module__ = __name__ 373 /home/marcel/programming/brian2/brian2/core/magic.pyc in run(self, duration, report, report_period, namespace, profile, level) 229 self._update_magic_objects(level=level+1) 230 Network.run(self, duration, report=report, report_period=report_period, --, 231 namespace=namespace, profile=profile, level=level+1) 232 233 def store(self, ...
You need to allow cookies if you want the configuration to be stored. If not, remember/bookmark the right URL that will be provided after submitting changes. You can override the settings by providing an extra arg to the URL (e.g. &buildd=1 if you want to display the buildd column). These args will not change the custom settings you defined before (the cookie is not modified ...
You need to allow cookies if you want the configuration to be stored. If not, remember/bookmark the right URL that will be provided after submitting changes. You can override the settings by providing an extra arg to the URL (e.g. &buildd=1 if you want to display the buildd column). These args will not change the custom settings you defined before (the cookie is not modified ...
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4, category_name => Photos & Videos ); $myposts = get_posts( $args ); foreach( $myposts as $post ) : setup_postdata($post ...
I did not get much luck with those recommendations either. I was doing = exactly the same. Something is phishy with my pymol and/or APBS = installation. I did check for different pdb files, so it is not pdb = related. The roor message is below: =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D= =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D= =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D= =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D= =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D Running (/usr/bin/APBS/apbs-0.5.0/bin/apbs, = /home/Vaheh/Work/Fc3M/pymol-generated.in) OSError Exception in Tk callback Function: ,function ,lambda, at 0xf608448c, (type: ,type function,) Args: () Traceback (innermost last): File = /usr/bin/pymol/ext/lib/python2.4/site-packages/Pmw/Pmw_1_2/lib/PmwBase.p= y, line 1747, in __call__ return apply(self.func, args) File = ...
public class Phylogeny { static public void main (String args[]) { SpeciesSet ss = new SpeciesSet (); ... (open file for reading) while (not end of file) { Species current = new Species (name from file, genome from file); ss.insert (current); } } public class SpeciesSet { private Vector els; public void insert (/*@[email protected]*/ Species s) { if (getIndex (s) < 0) els.add (s ...
The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _ new Title : new Usage : my $obj = Bio::Align::ProteinStatistics-,new(); Function: Builds a new Bio::Align::ProteinStatistics object Returns : an instance of Bio::Align::ProteinStatistics Args : distance Title : distance Usage : my $distance_mat = $stats-,distance(-align =, $aln, -method =, $method); Function: Calculates a distance matrix for all pairwise distances of sequences in an alignment. Returns : L,Bio::Matrix::PhylipDist, object Args : -align =, Bio::Align::AlignI object -method =, String specifying specific distance method (implementing class may assume a default) available_distance_methods Title : available_distance_methods Usage : my @methods = $stats-,available_distance_methods(); Function: Enumerates the possible distance methods Returns : Array of strings Args : none D - distance methods D_Kimura Title : D_Kimura Usage : my $matrix = $pepstats-,D_Kimura($aln); Function: ...
usr/locanl/bin/tclsh # FILE: /home/joze/src/tclreadline/tclreadlineSetup.tcl.in # LAST MODIFICATION: Sat, 01 Jul 2000 21:53:28 +0200 (joze) # (C) 1998 - 2000 by Johannes Zellner, ,[email protected], # $Id$ # --- # tclreadline -- gnu readline for tcl # http://www.zellner.org/tclreadline/ # Copyright (c) 1998 - 2000, Johannes Zellner ,[email protected], # This software is copyright under the BSD license. package provide tclreadline @[email protected] proc unknown args { global auto_noexec auto_noload env unknown_pending tcl_interactive global errorCode errorInfo # Save the values of errorCode and errorInfo variables, since they # may get modified if caught errors occur below. The variables will # be restored just before re-executing the missing command. set savedErrorCode $errorCode set savedErrorInfo $errorInfo set name [lindex $args 0] if ![info exists auto_noload] { # # Make sure were not trying to load the same proc twice. # if [info exists unknown_pending($name)] { return -code error ...
The pathological basis of multiple sclerosis involves damage to both myelin sheaths and axons. Demyelination and axonal transection are considered to cause reversible and irreversible neurological deficits respectively, gradually destroying the neuronal circuitry of the CNS. In order to analyse the individual effects of the pathological hallmarks of multiple sclerosis on neurons, the pontocerebellar pathway was targeted with either lysolecithin-induced chemical demyelination or complete pathway transection. Transcriptional changes in the pontocerebellar neuronal nuclei were investigated with microarrays at days 4, 10 and 37 post-intervention to identify underlying molecular responses. A common as well as unique set of injury response genes was identified in the transection and the demyelination conditions. The increased expression of activating transcription factor 3 (Atf3) and thyrotropin-releasing hormone (Trh) in both injury paradigms was validated by immunohistochemistry. Expression of Atf3 in a
Buy our Recombinant Human Arginyl tRNA synthetase protein. Ab114873 is a full length protein produced in Wheat germ and has been validated in WB, ELISA…
define (ask object message . args) (apply (get-method object message) object args)) (define (get-method object message) (object message)) (define make-object (lambda (name) (lambda (message) (case message ((class) (lambda (self) object)) ((object?) (lambda (self) #t)) ((name) (lambda (self) name)) (else (error "No method")))))) (define make-boat (lambda (name) (let ((super (make-object name)) (floating #t)) (lambda (message) (case message ((class) (lambda (self) boat)) ((boat?) (lambda (self) #t)) ((is-floating?) (lambda (self) floating)) ((sink) (lambda (self) (set! floating #f))) (else (get-method super message))))))) (define make-sail-boat (lambda (name) (let ((super (make-boat name)) (sailing #f)) (lambda (message) (case message ((class) (lambda (self) sail-boat)) ((raise-sail) (lambda (self) (set! sailing #t))) ((lower-sail) (lambda (self) (set! sailing #f))) (else (get-method super message ...
Usage: fossil unversioned SUBCOMMAND ARGS... or: fossil uv SUBCOMMAND ARGS.. Unversioned files (UV-files) are artifacts that are synced and are available for download but which do not preserve history. Only the most recent version of each UV-file is retained. Changes to an UV-file are permanent and cannot be undone, so use appropriate caution with this command. Subcommands: add FILE ... Add or update one or more unversioned files in the local repository so that they match FILEs on disk. Changes are not pushed to other repositories until the next sync. add FILE --as UVFILE Add or update a single file named FILE on disk and UVFILE in the repository unversioned file namespace. This variant of the add command allows the name to be different in the repository versus what appears on disk, but it only allows adding a single file at a time. cat FILE ... Concatenate the content of FILEs to stdout. edit FILE Bring up FILE in a text editor for modification. export FILE OUTPUT Write the content of FILE ...
Usage: fossil unversioned SUBCOMMAND ARGS... or: fossil uv SUBCOMMAND ARGS.. Unversioned files (UV-files) are artifacts that are synced and are available for download but which do not preserve history. Only the most recent version of each UV-file is retained. Changes to an UV-file are permanent and cannot be undone, so use appropriate caution with this command. Subcommands: add FILE ... Add or update one or more unversioned files in the local repository so that they match FILEs on disk. Changes are not pushed to other repositories until the next sync. add FILE --as UVFILE Add or update a single file named FILE on disk and UVFILE in the repository unversioned file namespace. This variant of the add command allows the name to be different in the repository versus what appears on disk, but it only allows adding a single file at a time. cat FILE ... Concatenate the content of FILEs to stdout. edit FILE Bring up FILE in a text editor for modification. export FILE OUTPUT Write the content of FILE ...
On Tue, 2016-11-29 at 11:56 +0800, Chris McCormick wrote: , Hi Roman, , , On 29/11/16 05:36, Roman Haefeli wrote: , , , , As far as I can see it, it is currently impossible to pass a , , variable , , number of arguments to child objects and also [list args] wouldnt , , address that. , Yes, you are right. You could do that with dynamic patching of , course , but I guess that answer is suboptimal for you ...
Admission representations and military recruiters are scheduled to visit ARGS and meet with your student on the dates listed below. ...
The beetle Caryedes brasiliensis is able to tolerate this however as it has the most highly discriminatory arginine-tRNA ligase ... presumably by virtue of highly discriminatory Arginine-tRNA ligase, the enzyme responsible for the first step in the ... of dietary canavanine because their arginine-tRNA ligase has little, if any, discriminatory capacity. No one has examined ... experimentally the arginine-tRNA synthetase of these organisms. But comparative studies of the incorporation of radiolabeled L- ...
In enzymology, an arginine-tRNA ligase (EC 6.1.1.19) is an enzyme that catalyzes the chemical reaction ATP + L-arginine + ... arginine-tRNA synthetase, and arginine translase. This enzyme participates in arginine and proline metabolism and aminoacyl- ... L-arginine, and tRNA(Arg), whereas its 3 products are AMP, diphosphate, and L-arginyl-tRNA(Arg). This enzyme belongs to the ... The systematic name of this enzyme class is L-arginine:tRNAArg ligase (AMP-forming). Other names in common use include arginyl- ...
... and prolinyl-tRNA ligase. This enzyme participates in arginine and proline metabolism and aminoacyl-trna biosynthesis. As of ... In enzymology, a proline-tRNA ligase (EC 6.1.1.15) is an enzyme that catalyzes the chemical reaction ATP + L-proline + tRNAPro ... and L-prolyl-tRNA(Pro). This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in ... aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-proline:tRNAPro ligase (AMP-forming). Other ...
... alanine-tRNA ligase MeSH D08.811.464.263.200.100 --- arginine-tRNA ligase MeSH D08.811.464.263.200.150 --- aspartate-tRNA ... isoleucine-trna ligase MeSH D08.811.464.263.200.500 --- leucine-trna ligase MeSH D08.811.464.263.200.550 --- lysine-trna ligase ... tyrosine-tRNA ligase MeSH D08.811.464.263.200.950 --- valine-tRNA ligase MeSH D08.811.464.267.500 --- coenzyme a ligases MeSH ... glutamate-trna ligase MeSH D08.811.464.263.200.350 --- glycine-trna ligase MeSH D08.811.464.263.200.400 --- histidine-trna ...
... has been shown to interact with EEF1G. Leucine-tRNA ligase GRCh38: Ensembl release 89: ENSG00000133706 ... It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C ... This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded ... Lue SW, Kelley SO (2007). "A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation ...
... cysteine-tRNA ligase EC 6.1.1.17: glutamate-tRNA ligase EC 6.1.1.18: glutamine-tRNA ligase EC 6.1.1.19: arginine-tRNA ligase EC ... threonine-tRNA ligase EC 6.1.1.4: leucine-tRNA ligase EC 6.1.1.5: isoleucine-tRNA ligase EC 6.1.1.6: lysine-tRNA ligase EC 6.1. ... valine-tRNA ligase EC 6.1.1.10: methionine-tRNA ligase EC 6.1.1.11: serine-tRNA ligase EC 6.1.1.12: aspartate-tRNA ligase EC ... phenylalanine-tRNA ligase EC 6.1.1.21: histidine-tRNA ligase EC 6.1.1.22: asparagine-tRNA ligase EC 6.1.1.23: aspartate-tRNAAsn ...
Ferber, S. dan Ciechanover, A. (1987) Role of Arginine-tRNA in Protein Degradation by the Ubiquitin Pathway. Nature 326,808-811 ... Hershko, A., Heller, H., Elias, S. dan Ciechanover, A. (1983) Components of ubiquitin-protein ligase system: resolution, ... Purification and characterization of arginyl-tRNA-protein transferase from rabbit reticulocytes: its involvement in ...
Aminoacyl tRNA synthetase *Alanine. *Arginine. *Asparagine. *Aspartate. *Cysteine. *D-alanine-poly(phosphoribitol) ligase ... Stage two involves four key Mur ubiquitin ligase enzymes: MurC (EC),[1] MurD (EC),[2] MurE (EC) [3] and MurF (EC).[4] These ... 6-diaminopimelate ligase (MurE), and UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (MurF). This entry also includes ... All four Mur ligases are topologically similar to one another, even though they display low sequence identity. They are each ...
Aminoacyl tRNA synthetase *Alanine. *Arginine. *Asparagine. *Aspartate. *Cysteine. *D-alanine-poly(phosphoribitol) ligase ... The common names of ligases often include the word "ligase", such as DNA ligase, an enzyme commonly used in molecular biology ... DNA ligase. References[edit]. *^ "Synthases and ligases". chem.qmul.ac.uk. Archived from the original on October 15, 2012. ... This article is about general ligases. For DNA specific ligases, see DNA ligase. ...
MetG1 (Methionine-tRNA ligase) is required for elongation of protein synthesis and the initiation of all mRNA translation ... It is proline and arginine rich and isoleucine, asparagine, phenylalanine, and tyrosine poor. The predicted secondary structure ... tRNA ligase GeneCard. 8orf58 Gene(Protein Coding) Chromosome 8 Open Reading Frame 58. [5].. ... through initiator tRNA(fMet) aminoacylation. An important paralog of this gene is ENSG00000248235. Orthologs of the human gene ...
Protein arginine methyltransferase 6 PSRC1: Proline/serine-rich coiled-coil protein 1 RAD54L: RAD54-like RAP1A (1p13) RBM15 ( ... E3 ubiquitin-protein ligase component n-recognin 4 UROD: uroporphyrinogen decarboxylase (the gene for porphyria cutanea tarda) ... Tryptophanyl-tRNA synthetase, mitochondrial WDR77 (1p13) YBX1 (1p34) ZCCHC17: zinc finger CCHC-type containing 17 ZMYM1 ... also known as arginine decarboxylase (ADC) BCAS2: Breast carcinoma amplified sequence 2 BCL10 (1p22) BCL2L15 (1p13) C1orf103: ...
UBR4: E3 ubiquitin-protein ligase component n-recognin 4. *UROD: uroporphyrinogen decarboxylase (the gene for porphyria cutanea ... AZIN2: encoding enzyme Antizyme inhibitor 2 (AzI2) also known as arginine decarboxylase (ADC) ... "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) ...
An aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase, is an enzyme that attaches the appropriate amino acid onto ... "Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases". PLoS Computational Biology ... If the incorrect tRNA is added (aka. the tRNA is found to be improperly charged), the aminoacyl-tRNA bond is hydrolyzed. This ... Delarue, M (1995). "Aminoacyl-tRNA synthetases". Structural Biology. 5: 48-55.. *^ "Molecule of the Month: Aminoacyl-tRNA ...
Ferber, S. lan Ciechanover, A. (1987) Role of Arginine-tRNA in Protein Degradation by the Ubiquitin Pathway. Nature 326,808-811 ... Hershko, A., Heller, H., Elias, S. lan Ciechanover, A. (1983) Components of ubiquitin-protéin ligase system: resolution, ... Purification and characterization of arginyl-tRNA-protéin transferase from rabbit reticulocytes: its involvement in ...
Putative substrates of parkin include synphilin-1, CDC-rel1, cyclin E, p38 tRNA synthase, Pael-R, synaptotagmin XI, sp22 and ... crystallisation of parkin revealed a cationic pocket in RING0 formed by lysine and arginine residues Lys161, Arg163 and Lys211 ... "Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases". Nature Communications. 4: 1982 ... Parkin (ligase) has been shown to interact with: Alpha-synuclein, CASK, CUL1, FBXW7 and GPR37, HSPA1A, HSPA8, Multisynthetase ...
Aminoacyl tRNA synthetase *Alanine. *Arginine. *Asparagine. *Aspartate. *Cysteine. *D-alanine-poly(phosphoribitol) ligase ... It represents the first committed step in pyrimidine and arginine biosynthesis in prokaryotes and eukaryotes, and in the urea ... cycle in most terrestrial vertebrates.[2] Most prokaryotes carry one form of CPSase that participates in both arginine and ...
Aminoacyl tRNA synthetase *Alanine. *Arginine. *Asparagine. *Aspartate. *Cysteine. *D-alanine-poly(phosphoribitol) ligase ... L-glutamine amido-ligase, (ADP-forming), 2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine, and amido-ligase (ADP- ... This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with ... The systematic name of this enzyme class is N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming ...
Aminoacyl tRNA synthetase *Alanine. *Arginine. *Asparagine. *Aspartate. *Cysteine. *D-alanine-poly(phosphoribitol) ligase ... E3 ligase activity[edit]. The E3 ubiquitin ligase MDM2 is a negative regulator of the p53 tumor suppressor protein. MDM2 binds ... ubiquitin protein ligase activity. • NEDD8 ligase activity. • disordered domain specific binding. • protein domain specific ... The RING domain of Mdm2 confers E3 ubiquitin ligase activity and is sufficient for E3 ligase activity in Mdm2 RING ...
Aminoacyl tRNA synthetase *Alanine. *Arginine. *Asparagine. *Aspartate. *Cysteine. *D-alanine-poly(phosphoribitol) ligase ... L-glutamine amido-ligase (AMP-forming).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction ...
... queuine tRNA-ribosyltransferase EC 2.4.2.30: NAD+ ADP-ribosyltransferase EC 2.4.2.31: NAD(P)+-protein-arginine ADP- ... protein ligase EC 2.7.7.64: UTP-monosaccharide-1-phosphate uridylyltransferase EC 2.7.7.65: diguanylate cyclase EC 2.7.7.66: ... tRNA (cytosine-5-)-methyltransferase EC 2.1.1.30: deleted EC 2.1.1.31: tRNA (guanine-N1-)-methyltransferase EC 2.1.1.32: tRNA ( ... arginine N-methyltransferase EC 2.1.1.125: histone-arginine N-methyltransferase EC 2.1.1.126: (myelin basic protein)-arginine N ...
... if a tRNA synthases loaded an incorrect amino acid onto a tRNA, the resulting peptide would have unexpectedly altered ... "The primordial metabolism: an ancestral interconnection between leucine, arginine, and lysine biosynthesis". BMC Evolutionary ... Perona JJ, Hadd A (November 2012). "Structural diversity and protein engineering of the aminoacyl-tRNA synthetases". ... properties, consequently to enhance fidelity several additional domains are present.[27] Similar in reaction to tRNA synthases ...
... arginine/serine-rich 14 SFRS16: encoding protein Splicing factor, arginine/serine-rich 16 SLC5A5: Solute carrier family 5 ( ... Gene map locus 19q13.2 FCGBP: Fc fragment of IgG binding protein SARS2: seryl-tRNA synthetase 2, mitochondrial. Gene map locus ... encoding enzyme Long-chain-fatty-acid-CoA ligase ANKRD24: encoding protein Ankyrin repeat domain-containing protein 24 ARMC6: ... "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) ...
005687 phenylalanyl-tRNA synthetase, beta subunit GARS (gene)GARS NM_002047 glycyl-tRNA synthetase HARS NM_002109 histidyl-tRNA ... arginine/serine-rich EIF1 aka SUI1 EIF1AD EIF1B EIF2A EIF2AK1 EIF2AK3 EIF2AK4 EIF2AK1 EIF2B2 EIF2B3 EIF2B4 EIF2S2 EIF3A EIF3B ... 021178 E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression ... 002884 arginyl-tRNA synthetase RARS2 NM_020320 arginyl-tRNA synthetase 2, mitochondrial SARS NM_006513 Homo sapiens seryl-tRNA ...
"TRDMT1 tRNA aspartic acid methyltransferase 1 (Homo sapiens)". Entrez Gene. NCBI. 2010-11-01. Retrieved 2010-11-07.. ... tRNA aspartic acid methyltransferase 1) to better reflect its biological function.[23] TRDMT1 is the first RNA cytosine ... "Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2". Science. 311 (5759): 395-398. doi:10.1126/science.1120976 ...
... the phenylalanine-tRNA ligase beta-subunit, VARS, elongation factor Tu, the RNA polymerase beta-subunit, and the ribosomal ... arginine, phenylalanine, and tryptophan. Some strains of Sulcia muelleri are incapable of making the amino acid, tryptophan. It ... Sulcia muelleri lacks a full set of Aminoacyl tRNA synthetases; surprisingly, however, it possesses all of the genes necessary ... The proteins used were the DNA polymerase III beta-subunit, initiation factor IF-2, leucyl-tRNA synthetase, ...
... tRNA ↽ − − ⇀ aminoacyl − tRNA + AMP {\displaystyle {\ce {{Aminoacyl-AMP}+ tRNA <=> {aminoacyl-tRNA}+ AMP}}} The combination of ... Okazaki fragments are covalently joined by DNA ligase to form a continuous strand. Then, to complete DNA replication, RNA ... In the first step of arginine biosynthesis in bacteria, glutamate is acetylated by transferring the acetyl group from acetyl- ... This reaction, called tRNA charging, is catalyzed by aminoacyl tRNA synthetase. A specific tRNA synthetase is responsible for ...
arginine→. *Ornithine aminotransferase. *Ornithine decarboxylase. *Agmatinase. →alpha-ketoglutarate→TCA. *Glutamate ...
Narayanan N, Wang Z, Li L, Yang Y (2017). "Arginine methylation of USP9X promotes its interaction with TDRD3 and its anti- ... eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules". Molecular Biology ... "Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity". Proceedings of the National ... Tsai WC, Reineke LC, Jain A, Jung SY, Lloyd RE (September 2017). "Histone arginine demethylase JMJD6 is linked to stress ...
Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg) ... in complex with substrate tRNA(Arg). To Be Published Release Date. 2017-05-31. Peptides. Arginine--tRNA ligase: AC. SMTL:PDB. ... Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg). Coordinates. PDB Format ... Zhou, M. et al., Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) ...
The SCOP classification for the Arginyl-tRNA synthetase (ArgRS), N-terminal additional domain superfamily including the ... INHERITED FROM: ligase activity ,, ligase activity, forming carbon-oxygen bonds ,, catalytic activity ,, arginine-tRNA ligase ... Ligases forming aminoacyl-tRNA and related compoun. 0. Moderately Informative. Direct. Enzyme Commission (EC). Arginine--tRNA ... Ligases. 0. 0.6568. Least Informative. DIRECT. Enzyme Commission (EC). Ligases forming aminoacyl-tRNA and related compoun. 0. ...
In enzymology, an arginine-tRNA ligase (EC 6.1.1.19) is an enzyme that catalyzes the chemical reaction ATP + L-arginine + ... arginine-tRNA synthetase, and arginine translase. This enzyme participates in arginine and proline metabolism and aminoacyl- ... L-arginine, and tRNA(Arg), whereas its 3 products are AMP, diphosphate, and L-arginyl-tRNA(Arg). This enzyme belongs to the ... The systematic name of this enzyme class is L-arginine:tRNAArg ligase (AMP-forming). Other names in common use include arginyl- ...
IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR036695. Arg-tRNA-synth_N_sf. ... IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR036695. Arg-tRNA-synth_N_sf. ... Arginine--tRNA ligaseUniRule annotation. ,p>Information which has been generated by the UniProtKB automatic annotation system, ... ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation. ,p>Information which has been ...
IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR035684. ArgRS_core. IPR008909. DALR_ ... IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR035684. ArgRS_core. IPR008909. DALR_ ... Arginine--tRNA ligaseUniRule annotation. ,p>Manual validated information which has been generated by the UniProtKB automatic ... ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation. ,p>Manual validated information ...
... where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded ...
Arginine--tRNA ligase. Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081). Loading... ... Arginine--tRNA ligase. Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334). Loading... ... Arginine--tRNA ligase. Methanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT). Loading... ... Arginine--tRNA ligase. Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1). Loading... ...
Buy our Recombinant Human Arginyl tRNA synthetase protein. Ab114873 is a full length protein produced in Wheat germ and has ... Arginine tRNA ligase. *Arginine tRNA ligase 1, cytoplasmic. *Arginine--tRNA ligase. *Arginyl tRNA synthetase 1 ... Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein ...
... arginine-tRNA ligase activity; IEA:InterPro. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0006420; P:arginyl-tRNA ...
L-arginine supplements may improve the quality of life and erectile function in men who are prostate cancer surv... ... Arginine-trna Ligase. An enzyme that activates arginine with its specific transfer RNA. EC 6.1.1.19. ... Arginine Kinase. An enzyme that catalyzes the phosphorylation of the guanidine nitrogen of arginine in the presence of ATP and ... L-Arginine Supplements in Treating Women Who Are Cancer Survivors. RATIONALE: L-arginine supplements may improve the quality of ...
... arginine-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN arginyl-tRNA aminoacylation (inferred); tRNA ... ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); ... ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); arginine-tRNA ligase activity (inferred); ATP ... arginine-tRNA ligase activity IEA. InterPro:IPR008909. 2290270. UniProtKB. GO_REF:0000002, MGI:MGI:2152098. ...
BP] arginyl-tRNA aminoacylation *[CC] cytoplasm *[MF] ATP binding *[MF] arginine-tRNA ligase activity ...
Probable arginine--tRNA ligase, cytoplasmic. Organism. Caenorhabditis elegans (AnAge). Potential relevance to longevity and/or ...
0913900 a putative arginine-tRNA ligase. When considering drug-resistant candidate polymorphism, crt mutations (K76T, Q271E, ...
Ligase; Nucleotide-binding; Protein biosynthesis. FT CHAIN 1 556 Arginine--tRNA ligase. FT /FTId=PRO_1000018054. FT MOTIF 132 ... DR InterPro; IPR001278; Arg-tRNA-ligase. DR InterPro; IPR005148; Arg-tRNA-synth_N. DR InterPro; IPR036695; Arg-tRNA-synth_N_sf ... DE RecName: Full=Arginine--tRNA ligase {ECO:0000255,HAMAP-Rule:MF_00123}; DE EC=6.1.1.19 {ECO:0000255,HAMAP-Rule:MF_00123}; DE ... DR GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:UniProtKB-EC. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO ...
Arginine-trna Ligase. An enzyme that activates arginine with its specific transfer RNA. EC 6.1.1.19. ... L-arginine add-on Therapy in Patients With Schizophrenia. This study evaluates the addition of L-Arginine to the usual regimen ... Study of Arginine and Nitric Oxide in Patients With Diabetes. This study will test the effect of arginine versus citrulline ... Arginine Kinase. An enzyme that catalyzes the phosphorylation of the guanidine nitrogen of arginine in the presence of ATP and ...
aja:AJAP_29485 Arginine-tRNA ligase K01887 574 104 ( -) 30 0.309 110 -, 1 apr:Apre_0153 Beta-glucosidase K01223 457 104 ( -) 30 ... lagg:B0E33_25740 glutamate--tRNA ligase K01885 474 106 ( -) 30 0.312 77 -, 1 lth:KLTH0D11902g KLTH0D11902p K04648 819 106 ( -) ... ahm:TL08_00170 arginyl-tRNA synthetase K01887 582 103 ( -) 29 0.305 105 -, 1 amo:Anamo_1277 urocanate hydratase K01712 679 103 ... aht:ANTHELSMS3_04207 DNA ligase B K10747 530 100 ( -) 29 0.307 140 -, 1 amed:B224_3976 sensor kinase CitA, putative 521 100 ...
jal:BZG29_04770 arginine--tRNA ligase K01887 569 103 ( -) 29 0.300 100 -, 1 jan:Jann_0374 Chromosome segregation protein SMC ... tRNA ligase, beta subun K01890 788 100 ( -) 29 0.303 122 -, 1 echs:ECHOSC_0381 phenylalanine--tRNA ligase, beta subun K01890 ... echw:ECHWAK_0680 phenylalanine--tRNA ligase, beta subun K01890 788 100 ( -) 29 0.303 122 -, 1 fgi:OP10G_3733 enolase K01689 432 ... abf:AMK58_11325 histidine--tRNA ligase K01892 449 110 ( -) 31 0.333 78 -, 1 bamf:U722_06060 ABC transporter ATP-binding protein ...
arginine-tRNA ligase activity (GO:0004814), nucleotide binding (GO:0000166), ATP binding (GO:0005524). ... The aminoacyl-tRNA synthetase (also known as aminoacyl-tRNA ligase) catalyse the attachment of an amino acid to its cognate ... Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition. ... THERMUS THERMOPHILUS ARGINYL-TRNA SYNTHETASE. 2zue. Crystal structure of Pyrococcus horikoshii arginyl-tRNA synthetase ...
The beetle Caryedes brasiliensis is able to tolerate this however as it has the most highly discriminatory arginine-tRNA ligase ... presumably by virtue of highly discriminatory Arginine-tRNA ligase, the enzyme responsible for the first step in the ... of dietary canavanine because their arginine-tRNA ligase has little, if any, discriminatory capacity. No one has examined ... experimentally the arginine-tRNA synthetase of these organisms. But comparative studies of the incorporation of radiolabeled L- ...
Bacteriophage T4 RNA ligase 2 (gp24.1) exemplifies a family of RNA ligases found in all phylogenetic domains ... in addition to tRNA2Gln, tRNALys, and tRNAGlu. This is also the case for tRNACys, tRNATrp, tRNA3Ser, tRNA2Gly, and tRNA3Gly, ... for tRNAArgCCU (18). The DNA probes for control RNAs, tRNATyr, tRNAHis, tRNAAsn tRNAAsp, tRNA2Gln, tRNALys, tRNAGlu, and 16S- ... tRNAArgCCG, tRNAArgU*CU, and tRNAArgCCU. As shown in Fig. 3, not only tRNAArgICG but also tRNAArgCCG, tRNAArgU*CU, and tRNAArg ...
... hydroxyl of the tRNA, while, in class II reactions, the 3-hydroxyl site is preferred. The synthetases specific for arginine, ... Isoleucine-tRNA ligase (IPR002301). Short name: Ile-tRNA-ligase Family relationships *Isoleucine-tRNA ligase (IPR002301) * ... Isoleucine-tRNA ligase (also known as Isoleucyl-tRNA synthetase)(EC:6.1.1.5) is an alpha monomer that belongs to class Ia. The ... The aminoacyl-tRNA synthetase (also known as aminoacyl-tRNA ligase) catalyse the attachment of an amino acid to its cognate ...
arginyl-tRNA aminoacylation (GO:0006420). GO function:. arginine-tRNA ligase activity (GO:0004814), ATP binding (GO:0005524). ... Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition. ... THERMUS THERMOPHILUS ARGINYL-TRNA SYNTHETASE. 2zue. Crystal structure of Pyrococcus horikoshii arginyl-tRNA synthetase ... CRYSTAL STRUCTURE OF THE ARGINYL-TRNA SYNTHETASE COMPLEXED WITH THE TRNA(ARG) AND L-ARG. ...
Arginyi-tRNA synthetase Current Synonym true false 2971785015 Arginine-transfer ribonucleic acid ligase Current Synonym true ... Arginine-transfer ribonucleic acid ligase (substance). Code System Preferred Concept Name. Arginine-transfer ribonucleic acid ... Arginine-tRNA ligase Current Synonym true false 108295010 ... Substance with ligase mechanism of action (substance) {1672007 ...
Buy online RARS-arginyl-tRNA synthetase Gene from ProteoGenix cat# PTXBC000528. Shop among our wide range of DNA & ... arginyl-tRNA synthetase. Synonyms: ArgRS; DALRD1; HLD9; arginine--tRNA ligase, cytoplasmic; arginine tRNA ligase 1, cytoplasmic ... arginyl-tRNA synthetase, cytoplasmic; arginyl-tRNA synthetase. Sequence primers: Forward primer M13R (5→3): GTAAAACGACGGCCAGT ... More info about RARS-arginyl-tRNA synthetase Gene. Availability: PRODUCT NOT AVAILABLE. ...
  • Two mecillinam resistant mutants, lov-1 and lovB, both able to dispense entirely with PBP2, are shown here to be affected in the aminoacyl-tRNA synthetase genes argS and alaS, respectively. (microbialphenotypes.org)
  • BLASTN P-value scores are indicated for RSTs having homology with rDNA and tRNA genes of S. cerevisiae . (gsf.de)
  • Using a genome-wide approach in the fission yeast S. pombe, this study found that Dcr1 (see Drosophila Dicer-1 ), but not other components of the canonical RNAi pathway, promotes the release of Pol II (see Drosophila Pol2 ) from the 3' end of highly transcribed genes, and, surprisingly, from antisense transcription of rRNA and tRNA genes, which are normally transcribed by Pol I and Pol III. (sdbonline.org)
  • The genome also included four genes specifying tRNAs. (biomedcentral.com)
  • The 3′ ends of tRNA and other RNA polymerase III (Pol III)-dependent genes contain dT n termination signals at which Pol III pauses and releases its RNA ( 6 ). (pubmedcentralcanada.ca)
  • The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules. (ebi.ac.uk)
  • We also identify a paralogous version of the methionyl-tRNA synthetase, which is widespread in bacteria, and present evidence using contextual information that it might function independently of protein synthesis as a peptide ligase in the formation of a peptide- derived secondary metabolite. (biomedcentral.com)
  • This metabolite is likely to be heavily modified through multiple reactions catalyzed by a metal-binding cupin domain and a lysine N6 monooxygenase that are strictly associated with this paralogous methionyl-tRNA synthetase (MtRS). (biomedcentral.com)
  • leading to Vision IP, an initiation of the World Intellectual Property Organization( WIPO) was to binding recessive to zone, less than 5 metabolism of deficiencies have probable in connective complexes p53-dependent as Braille or many factors within the poor disease of ligase, while 33 physical of gangliosides with well domains and 47 maintenance of thus intracellular mechanisms circulate endothelial to initiate aggregates in the winds they bind. (evakoch.com)
  • Here, we show that colicin D specifically cleaves tRNAs Arg including four isoaccepting molecules both in vivo and in vitro . (pnas.org)
  • Other common names for ligases include the word "synthetase", because they are used to synthesize new molecules. (wikipedia.org)
  • The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. (princeton.edu)
  • tRNA molecules are misaminoacylated with non-radioactive markers which may be non-native amino acids, amino acid analogs. (google.ca)
  • tRNA molecules are misaminoacylated with non-radioactive markers which may be non-native amino acids, amino acid analogs or derivatives, or substances recognized by the protein synthesizing machinery. (google.ca)
  • It is structurally related to the proteinogenic α-amino acid L-arginine, the sole difference being the replacement of a methylene bridge (-CH 2- unit) in arginine with an oxa group (i.e., an oxygen atom) in canavanine. (wikipedia.org)
  • Each aaRS contains a catalytic central domain (CCD), responsible for activating amino acid, and an anticodon-binding domain (ABD), necessary for binding the anticodon in cognate tRNA. (embl-heidelberg.de)
  • Consistent with the cleavage of tRNAs Arg , the RNA fraction of colicin-treated cells significantly reduced the amino acid-accepting activity only for arginine. (pnas.org)
  • Suzuki M, Takahashi Y, Noguchi A, Arai T, Yagasaki M, Kino K, Saito J.The structure of L -amino-acid ligase from Bacillus licheniformis.Acta Crystallogr D Biol Crystallogr. (kyowahakko-bio.co.jp)
  • The argS and alaS mutants have high pools of the nucleotide ppGpp (effector of the stringent response) and the mecillinam resistance of both mutations is suppressed by a relA mutation, inactivating the ribosome-associated ppGpp synthetase and preventing ppGpp synthesis in response to aminoacyl-tRNA starvation. (microbialphenotypes.org)
  • Moreover, existing drugs that deplete asparagine and arginine may be effective against brain tumors, and should be studied in conjunction with chemotherapy. (beds.ac.uk)
  • The data indicate that Rpc11p limits RNA 3′-U length and that this significantly restricts pre-tRNAs to a La-independent pathway of maturation in fission yeast. (pubmedcentralcanada.ca)
  • While La-homologous protein (Lhp1p) is nonessential in the yeast Saccharomyces cerevisiae (and in Schizosaccharomyces pombe ), its deletion causes lethality or growth deficiency in combination with mutations that impair base pairing or modification of certain pre-tRNAs, indicating that defective pre-tRNAs can be salvaged by La ( 5 , 7 , 21 , 38 ). (pubmedcentralcanada.ca)
  • An opal suppressor tRNA Ser UGAM gene with a dT 7 terminator ( tRNAmSer7T ), which suppresses a nonsense mutation in the ade6 - 704 allele and accumulation of red pigment, has been used to study tRNA biogenesis and the function of the La homolog, Sla1p, in the yeast S. pombe . (pubmedcentralcanada.ca)
  • These four Mur ligases are responsible for the successive additions of L-alanine, D-glutamate, meso- diaminopimelate or L-lysine, and D-alanyl-D-alanine to UDP- N-acetylmuramic acid . (wikipedia.org)
  • This family includes UDP-N-acetylmuramate-L-alanine ligase (MurC), UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase (MurE), and UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (MurF). (wikipedia.org)
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. (cathdb.info)
  • [n The necessity for this ligand also connects the high concentration of nitrogen, reflected in excess of glutamate and arginine to produce NAG, to an increase in CPSI activity to clear this excess. (wikidoc.org)
  • This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. (mssm.edu)
  • The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. (mssm.edu)
  • This stays because late conditions are required displaced to be specific caspase-1 and Toll-like intracellular production protons physical to next t gene, downstream cisternae of receptors are higher than in the CETN2 tRNA, and when there are carnitine VOCs reaction, they can be ribosomal and 6(1 GHGs. (evakoch.com)
  • The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. (wikidoc.org)
  • Bi-allelic mutations in Phe-tRNA synthetase associated with a multi-system pulmonary disease support non-translational function. (expasy.org)
  • Furthermore, we generated a single mutation of histidine in the C-terminal possible catalytic domain, which caused the loss of the killing activity in vivo together with the tRNA Arg -cleaving activity both in vivo and in vitro . (pnas.org)
  • A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity. (embl-heidelberg.de)
  • Despite these apparently similar actions on tRNAs and cells, colicins D and E5 not only exhibit no sequence homology but also have different molecular mechanisms as to both substrate recognition and catalytic reaction. (pnas.org)
  • Alternatively they might supply aminoacylated tRNAs for other biosynthetic pathways like that for tetrapyrrole or directly function as peptide ligases as in the case of mycothiol and those identified here. (biomedcentral.com)
  • Multiple reports indicate that yeasts use La-dependent and -independent pathways for tRNA maturation, with defective pre-tRNAs being most sensitive to decay and most dependent on La for maturation and function. (pubmedcentralcanada.ca)
  • Finding the reverse order suggests that different pre-tRNAs use the La-independent and -dependent pathways to various degrees ( 25 ). (pubmedcentralcanada.ca)
  • Mutations in pre-tRNA Ser UGAM that confer dependence on La also appear to cause it to be temperature sensitive, recognized poorly by RNase P, and cleaved aberrantly ( 13 , 35 ). (pubmedcentralcanada.ca)
  • Arginine, N(2)-acetylarginine and N(2)-glutamylarginine do not act as substrates. (cathdb.info)
  • Two conserved arginine residues (R325 and R335) were identified in Merlin that addition to the FERM domain, are required for interaction with Sip1. (sdbonline.org)
  • Mutation of the arginine residues result in reduced Sip1 binding to Merlin and loss of Merlin growth suppressor function. (sdbonline.org)
  • Recently, we found that colicin E5 stops protein synthesis by cleaving the anticodons of specific tRNAs for Tyr, His, Asn, and Asp. (pnas.org)
  • E5 is a novel RNase that cleaves the anticodons of tRNA Tyr , tRNA His , tRNA Asn , and tRNA Asp , which leads to impairment of protein synthesis and cell death. (pnas.org)
  • A seven amino acids long loop between beta-strands β3/β4 is crucial for EF-P function and modified at its tip by lysylation of lysine or rhamnosylation of arginine. (frontiersin.org)