A species of extremely thermophilic, sulfur-reducing archaea. It grows at a maximum temperature of 95 degrees C. in marine or deep-sea geothermal areas.
A genus of extremely thermophilic, sulfate-reducing archaea, in the family Archaeoglobaceae.
Proteins found in any species of archaeon.
An order of extremely thermophilic, sulfate-reducing archaea, in the kingdom EURYARCHAEOTA. The single family Archaeoglobaceae contains one genus ARCHAEOGLOBUS.
Ribonucleic acid in archaea having regulatory and catalytic roles as well as involvement in protein synthesis.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in archaea.
Proteins, usually acting in oxidation-reduction reactions, containing iron but no porphyrin groups. (Lehninger, Principles of Biochemistry, 1993, pG-10)
A genus of anaerobic coccoid METHANOCOCCACEAE whose organisms are motile by means of polar tufts of flagella. These methanogens are found in salt marshes, marine and estuarine sediments, and the intestinal tract of animals.
Deoxyribonucleic acid that makes up the genetic material of archaea.
An enzyme found primarily in SULFUR-REDUCING BACTERIA where it plays an important role in the anaerobic carbon oxidation pathway.
One of the three domains of life (the others being BACTERIA and Eukarya), formerly called Archaebacteria under the taxon Bacteria, but now considered separate and distinct. They are characterized by: (1) the presence of characteristic tRNAs and ribosomal RNAs; (2) the absence of peptidoglycan cell walls; (3) the presence of ether-linked lipids built from branched-chain subunits; and (4) their occurrence in unusual habitats. While archaea resemble bacteria in morphology and genomic organization, they resemble eukarya in their method of genomic replication. The domain contains at least four kingdoms: CRENARCHAEOTA; EURYARCHAEOTA; NANOARCHAEOTA; and KORARCHAEOTA.
Oxidoreductases with specificity for oxidation or reduction of SULFUR COMPOUNDS.
The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The functional genetic units of ARCHAEA.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
The extent to which an enzyme retains its structural conformation or its activity when subjected to storage, isolation, and purification or various other physical or chemical manipulations, including proteolytic enzymes and heat.
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Membrane proteins whose primary function is to facilitate the transport of positively charged molecules (cations) across a biological membrane.
Enzymes that catalyze the transfer of hydroxymethyl or formyl groups. EC 2.1.2.
A phylum of ARCHAEA comprising at least seven classes: Methanobacteria, Methanococci, Halobacteria (extreme halophiles), Archaeoglobi (sulfate-reducing species), Methanopyri, and the thermophiles: Thermoplasmata, and Thermococci.
An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway.
Compounds based on 2-amino-4-hydroxypteridine.
Transferases are enzymes transferring a group, for example, the methyl group or a glycosyl group, from one compound (generally regarded as donor) to another compound (generally regarded as acceptor). The classification is based on the scheme "donor:acceptor group transferase". (Enzyme Nomenclature, 1992) EC 2.
Enzymes that catalyze the joining of glutamine-derived ammonia and another molecule. The linkage is in the form of a carbon-nitrogen bond. EC 6.3.5.
A species of gram-negative, anaerobic, rod-shaped bacteria isolated from soil, animal intestines and feces, and fresh and salt water.
An order of extremely halophilic archaea, in the kingdom EURYARCHAEOTA. They occur ubiquitously in nature where the salt concentration is high, and are chemoorganotrophic, using amino acids or carbohydrates as a carbon source.
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)
A genus of gram-negative, aerobic bacteria in the family MORAXELLACEAE, associated with processed MEAT; FISH PRODUCTS; and POULTRY PRODUCTS.
An absence of warmth or heat or a temperature notably below an accustomed norm.
A genus of gram-negative rod-shaped bacteria in the class GAMMAPROTEOBACTERIA. They are obligately acidophilic and aerobic, using reduced SULFUR COMPOUNDS to support AUTOTROPHIC GROWTH.
Usually a hydroxide of lithium, sodium, potassium, rubidium or cesium, but also the carbonates of these metals, ammonia, and the amines. (Grant & Hackh's Chemical Dictionary, 5th ed)
A genus of gram-negative, anaerobic, rod-shaped bacteria capable of reducing sulfur compounds to hydrogen sulfide. Organisms are isolated from anaerobic mud of fresh and salt water, animal intestines, manure, and feces.
A group of gram-negative, anaerobic bacteria that is able to oxidize acetate completely to carbon dioxide using elemental sulfur as the electron acceptor.
5'-Adenylic acid, monoanhydride with sulfuric acid. The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Habitat of hot water naturally heated by underlying geologic processes. Surface hot springs have been used for BALNEOLOGY. Underwater hot springs are called HYDROTHERMAL VENTS.
Hot springs on the ocean floor. They are commonly found near volcanically active places such as mid-oceanic ridges.
A genus of extremely thermophilic heterotrophic archaea, in the family THERMOCOCCACEAE, occurring in heated sea flows. They are anaerobic chemoorganotropic sulfidogens.
Presence of warmth or heat or a temperature notably higher than an accustomed norm.
The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.
A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.
The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.

Identification of the Archaeoglobus fulgidus endonuclease III DNA interaction surface using heteronuclear NMR methods. (1/193)

BACKGROUND: Endonuclease III is the prototype for a family of DNA-repair enzymes that recognize and remove damaged and mismatched bases from DNA via cleavage of the N-glycosidic bond. Crystal structures for endonuclease III, which removes damaged pyrimidines, and MutY, which removes mismatched adenines, show a highly conserved structure. Although there are several models for DNA binding by this family of enzymes, no experimental structures with bound DNA exist for any member of the family. RESULTS: Nuclear magnetic resonance (NMR) spectroscopy chemical-shift perturbation of backbone nuclei (1H, 15N, 13CO) has been used to map the DNA-binding site on Archaeoglobus fulgidus endonuclease III. The experimentally determined interaction surface includes five structural elements: the helix-hairpin-helix (HhH) motif, the iron-sulfur cluster loop (FCL) motif, the pseudo helix-hairpin-helix motif, the helix B-helix C loop, and helix H. The elements form a continuous surface that spans the active site of the enzyme. CONCLUSIONS: The enzyme-DNA interaction surface for endonuclease III contains five elements of the protein structure and suggests that DNA damage recognition may require several specific interactions between the enzyme and the DNA substrate. Because the target DNA used in this study contained a generic apurinic/apyrimidinic (AP) site, the binding interactions we observed for A. fulgidus endonuclease III should apply to all members of the endonuclease III family and several interactions could apply to the endonuclease III/AlkA (3-methyladenine DNA glycosylase) superfamily.  (+info)

Identification and characterization of a novel ferric reductase from the hyperthermophilic Archaeon Archaeoglobus fulgidus. (2/193)

Archaeoglobus fulgidus, a hyperthermophilic sulfate-reducing Archaeon, contains high Fe(3+)-EDTA reductase activity in its soluble protein fraction. The corresponding enzyme, which constitutes about 0.75% of the soluble protein, was purified 175-fold to homogeneity. Based on SDS-polyacrylamide gel electrophoresis, the ferric reductase consists of a single subunit with a M(r) of 18,000. The M(r) of the native enzyme was determined by size exclusion chromatography to be 40,000 suggesting that the native ferric reductase is a homodimer. The enzyme uses both NADH and NADPH as electron donors to reduce Fe(3+)-EDTA. Other Fe(3+) complexes and dichlorophenolindophenol serve as alternative electron acceptors, but uncomplexed Fe(3+) is not utilized. The purified enzyme strictly requires FMN or FAD as a catalytic intermediate for Fe(3+) reduction. Ferric reductase also reduces FMN and FAD, but not riboflavin, with NAD(P)H which classifies the enzyme as a NAD(P)H:flavin oxidoreductase. The enzyme exhibits a temperature optimum of 88 degrees C. When incubated at 85 degrees C, the enzyme activity half-life was 2 h. N-terminal sequence analysis of the purified ferric reductase resulted in the identification of the hypothetical gene, AF0830, of the A. fulgidus genomic sequence. The A. fulgidus ferric reductase shares amino acid sequence similarity with a family of NAD(P)H:FMN oxidoreductases but not with any ferric reductases suggesting that the A. fulgidus ferric reductase is a novel enzyme.  (+info)

The Archaeoglobus fulgidus D-lactate dehydrogenase is a Zn(2+) flavoprotein. (3/193)

Archaeoglobus fulgidus, a hyperthermophilic, archaeal sulfate reducer, is one of the few organisms that can utilize D-lactate as a sole source for both carbon and electrons. The A. fulgidus open reading frame, AF0394, which is predicted to encode a D-(-)-lactate dehydrogenase (Dld), was cloned, and its product was expressed in Escherichia coli as a fusion with the maltose binding protein (MBP). The 90-kDa MBP-Dld fusion protein was more efficiently expressed in E. coli when coexpressed with the E. coli dnaY gene, encoding the arginyl tRNA for the codons AGA and AGG. When cleaved from the fusion protein by treatment with factor Xa, the recombinant Dld (rDld) has an apparent molecular mass of 50 kDa, similar to that of the native A. fulgidus Dld enzyme. Both the purified MBP-Dld fusion protein and its rDld cleavage fragment have lactate dehydrogenase activities specific for D-lactate, are stable at 80 degrees C, and retain activity after exposure to oxygen. The flavin cofactor FAD, which binds rDld apoprotein with a 1:1 stoichiometry, is essential for activity.  (+info)

Cellulosome-like sequences in Archaeoglobus fulgidus: an enigmatic vestige of cohesin and dockerin domains. (4/193)

The distribution of cellulosomal cohesin domains among the sequences currently compiled in various sequence databases was investigated. Two cohesin domains were detected in two consecutive open reading frames (ORFs) of the recently sequenced genome of the archaeon Archaeoglobus fulgidus. Otherwise, no cohesin-like sequence could be detected in organisms other than those of the Eubacteria. One of the A. fulgidus cohesin-containing ORFs also harbored a dockerin domain, but the additional modular portions of both genes are undefined, both with respect to sequence homology and function. It is currently unclear what function(s) the putative cohesin and dockerin-containing proteins play in the life cycle of this organism. In particular, since A. fulgidus contains no known glycosyl hydrolase gene, the presence of a cellulosome can be excluded. The results suggest that cohesin and dockerin signature sequences cannot be used alone for the definitive identification of cellulosomes in genomes.  (+info)

Assembly of archaeal signal recognition particle from recombinant components. (5/193)

Signal recognition particle (SRP) takes part in protein targeting and secretion in all organisms. Searches for components of archaeal SRP in primary databases and completed genomes indicated that archaea possess only homologs of SRP RNA, and proteins SRP19 and SRP54. A recombinant SRP was assembled from cloned, expressed and purified components of the hyperthermophilic archaeon Archaeoglobus fulgidus. Recombinant Af-SRP54 associated with the signal peptide of bovine pre-prolactin translated in vitro. As in mammalian SRP, Af-SRP54 binding to Af-SRP RNA required protein Af-SRP19, although notable amounts bound in absence of Af-SRP19. Archaeoglobus fulgidus SRP proteins also bound to full-length SRP RNA of the archaeon Methanococcus jannaschii, to eukaryotic human SRP RNA, and to truncated versions which corresponded to the large domain of SRP. Dependence on SRP19 was most pronounced with components from the same species. Reconstitutions with heterologous components revealed a significant potential of human SRP proteins to bind to archaeal SRP RNAs. Surprisingly, M.jannaschii SRP RNA bound to human SRP54M quantitatively in the absence of SRP19. This is the first report of reconstitution of an archaeal SRP from recombinantly expressed purified components. The results highlight structural and functional conservation of SRP assembly between archaea and eucarya.  (+info)

Homology modeling and identification of serine 160 as nucleophile of the active site in a thermostable carboxylesterase from the archaeon Archaeoglobus fulgidus. (6/193)

The hyperthermophilic Archaeon Archaeoglobus fulgidus has a gene (AF1763) which encodes a thermostable carboxylesterase belonging to the hormone-sensitive lipase (HSL)-like group of the esterase/lipase family. Based on secondary structure predictions and a secondary structure-driven multiple sequence alignment with remote homologous proteins of known three-dimensional structure, we previously hypothesized for this enzyme the alpha/beta-hydrolase fold typical of several lipases and esterases and identified Ser160, Asp 255 and His285 as the putative members of the catalytic triad. In this paper we report the building of a 3D model for this enzyme based on the structure of the homologous brefeldin A esterase from Bacillus subtilis whose structure has been recently elucidated. The model reveals the topological organization of the fold corroborating our predictions. As regarding the active-site residues, Ser160, Asp255 and His285 are located close each other at hydrogen bond distances. The catalytic role of Ser160 as the nucleophilic member of the triad is demonstrated by the [(3)H]diisopropylphosphofluoridate (DFP) active-site labeling and sequencing of a radioactive peptide containing the signature sequence GDSAGG.  (+info)

Uracil-DNA glycosylase in the extreme thermophile Archaeoglobus fulgidus. (7/193)

Uracil-DNA glycosylase (UDG) is an essential enzyme for maintaining genomic integrity. Here we describe a UDG from the extreme thermophile Archaeoglobus fulgidus. The enzyme is a member of a new class of enzymes found in prokaryotes that is distinct from the UDG enzyme found in Escherichia coli, eukaryotes, and DNA-containing viruses. The A. fulgidus UDG is extremely thermostable, maintaining full activity after heating for 1.5 h at 95 degrees C. The protein is capable of removing uracil from double-stranded DNA containing either a U/A or U/G base pair as well as from single-stranded DNA. This enzyme is product-inhibited by both uracil and apurinic/apyrimidinic sites. The A. fulgidus UDG has a high degree of similarity at the primary amino acid sequence level to the enzyme found in Thermotoga maritima, a thermophilic eubacteria, and suggests a conserved mechanism of UDG-initiated base excision repair in archaea and thermophilic eubacteria.  (+info)

The Archean sulfur cycle and the early history of atmospheric oxygen. (8/193)

The isotope record of sedimentary sulfides can help resolve the history of oxygen accumulation into the atmosphere. We measured sulfur isotopic fractionation during microbial sulfate reduction up to 88 degrees C and show how sulfate reduction rate influences the preservation of biological fractionations in sediments. The sedimentary sulfur isotope record suggests low concentrations of seawater sulfate and atmospheric oxygen in the early Archean (3.4 to 2.8 billion years ago). The accumulation of oxygen and sulfate began later, in the early Proterozoic (2.5 to 0.54 billion years ago).  (+info)

cansSAR 3D Structure of 1S3Q_D | CRYSTAL STRUCTURES OF A NOVEL OPEN PORE FERRITIN FROM THE HYPERTHERMOPHILIC ARCHAEON ARCHAEOGLOBUS FULGIDUS | 1S3Q
cansSAR 3D Structure of 1S3Q_B | CRYSTAL STRUCTURES OF A NOVEL OPEN PORE FERRITIN FROM THE HYPERTHERMOPHILIC ARCHAEON ARCHAEOGLOBUS FULGIDUS | 1S3Q
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
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Adenylylsulphate (adenosine-5′-phosphosulphate, APS) reductase from the extremely thermophilic sulphate-reducing archaeon Archaeoglobus fulgidus is an iron-sulphur flavoprotein containing one non-covalently bound flavin group, eight non-haem iron and six labile sulphide atoms per molecule. Re-evaluation of the enzyme structure revealed the presence of two different subunits with molecular masses of 80 and 18.5 kDa. The subunits are arranged in an α2β subunit structure. We have cloned and sequenced a 2.7 kb segment of DNA containing the genes for the α and β subunits, which we designate aprA and aprB, respectively. The two genes are separated by 17 bp and localized in the order aprBA. While a putative promoter could not be identified in the vicinity of aprBA a probable termination signal was found just downstream of the translation stop codon of aprA. The codon usage for aprBA shows strong preferences for G and C in the third codon position. aprA encodes a 73.3 kDa polypeptide, which shows
A flavoprotein. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The enzyme from the hyperthermophilic archaeon Archaeoglobus fulgidus is not active with uncomplexed Fe(III). cf. EC 1.16.1.7, ferric-chelate reductase (NADH) and EC 1.16.1.9, ferric-chelate reductase (NADPH ...
1LJO: Archaeal Sm proteins form heptameric and hexameric complexes: crystal structures of the Sm1 and Sm2 proteins from the hyperthermophile Archaeoglobus fulgidus.
The zinc flavoprotein (FAD) from the archaeon Archaeoglobus fulgidus cannot utilize NAD+, cytochrome c, methylene blue or dimethylnaphthoquinone as acceptors. In vitro it is active with artificial electron acceptors such as 2,6-dichlorophenolindophenol, but the physiological acceptor is not yet known ...
The Archaeoglobus fulgidus genome is a circular chromosome roughly half the size of E. coli at 2,178,000 base pairs. A quarter of the genome encodes preserved proteins whose functions are not yet determined, but are expressed in other archaeons such as Methanococcus jannaschii. Another quarter encodes proteins unique to the archaeal domain. One observation about the genome is that there are many gene duplications and the duplicated proteins are not identical. This suggests metabolic differentiation specifically with respect to the decomposing and recycling carbon pathways through scavenged fatty acids. The duplicated genes also gives the genome a larger genome size than its fellow archaeon M. jannaschii. It is also noted that Archaeoglobus contained no inteins in coding regions where M. jannaschii had 18. ...
Huber, H., Jannasch, H., Rachel, R., Fuchs, T., and Stetter, K.O. 1997. Archaeoglobus veneficus sp. nov., a novel facultative chemolithoautotrophic hyperthermophilic sulfite reducer, isolated from abyssal black smokers. Syst. Appl. Microbiol. 20:374-380 ...
Ammonium transport (Amt) proteins are ubiquitous integral membrane proteins that transport NH4+ across cell membranes. Amt proteins involved in the uptake of NH4+ as direct N-source for biosynthesis are present in prokaryotes, archaea and plants [1]. In mammals, Rhesus proteins are the Amt homologs and their presence in erythrocyte, kidney and liver cell membranes can be directly related to NH3/NH4+ detoxification and pH homeostasis processes [2]. Long recognized for their immunogenic characteristics and involvement in hemolytic diseases of infants, a number of genetic diseases have been associated with the inability to correctly express Rh proteins [2,3]. Understanding the molecular details of transport and regulation of Amt proteins is therefore highly relevant to help treat and solve many human Rh-related diseases.. A significant amount of our research has focused on the archaea homologs, in particular on the Af-Amt1 protein from Archaeoglobus fulgidus. We have solved the crystal structures ...
Comparative analysis of the protein sequences encoded in the foureuryarchaeal species whose genomes have been sequenced completely(Methanococcus jannaschii, Methanobacterium thermoautotrophicum,Archaeoglobus fulgidus, and Pyrococcus horikoshii) revealed 1326orthologous sets, of which 543 are represented in all four species. Theproteins that belong to these conserved euryarchaeal families comprise31%-35% of the gene complement and may be considered the evolutionarilystable core of the archaeal genomes. The core gene set includes the greatmajority of genes coding for proteins involved in genome replication andexpression, but only a relatively small subset of metabolic functions. Formany gene families that are conserved in all euryarchaea, previouslyundetected orthologs in bacteria and eukaryotes were identified. A numberof euryarchaeal synapomorphies (unique shared characters) were identified;these are protein families that possess sequence signatures or domainarchitectures that are conserved in ...
fig 3 conservation of glutamate switch in AAA+ proteins. (a) Sequence alignments of selected members of each clade for which the crystal structures are known. The color scheme follows that used in Figure 4. RFCs, replication factor C small subunit from Archaeoglobus fulgidus; Orc1, Orc1 protein from Aeropyrum pernix; p97D1, p97 D1 AAA+ domain from Mus musculus; SV40, SV40 large T antigen; PspF, PspF from Escherichia coli; HslU, HslU from E. coli; RuvBL1, RuvB-like 1 (TIP49a, Pontin) from Homo sapiens. (b) Plot of side chain torsion angles for 50 active site glutamate (DExx box) residues from AAA+ protein structures in the Protein Data Bank (http://www.rcsb.org/) with a resolution better than 3.5 Å. Only one copy from the asymmetric unit was used if angles were similar, to reduce redundancy. The appropriate glutamate residue was selected from individual PDB files and the side chain torsion angles were calculated using the CCP4 program ANGLES40, then normalized to 0-360° for display. The values ...
SWISS-MODEL Template Library (SMTL) entry for 3gde.1. The closed conformation of ATP-dependent DNA ligase from Archaeoglobus fulgidus
Sequence logo and spacer length distribution of representative signals for the genomes (A) E. coli k-12; (B) S. coelicolor; (C) A. fulgidus; and (C) Synechocyst
Este un tip special de glaucom care atinge un numar mai scazut de pacienti in raport cu glaucomul cronic simplu (desi nu cu foarte mult). Este tot un tip de glaucom primitiv (apare pe ochi care nu au avut alte boli) si deci este INTOTDEAUNA BILATERAL (afecteaza ambii ochi). Se poate descoperi si intamplator cu ocazia unui examen oftalmologic minutios dar in general este descoperit din pacate cu o complicatie grava si anume GLAUCOMUL ACUT sau ATACUL ACUT de GLAUCOM.. Atacul de glaucom sau glaucomul acut este una din marile urgente oftalmologice. Debuteaza cu dureri intense la un ochi, hiperemie (inrosire) moderata, pupila este in semimidriaza (mai mare) fixa, nu se micsoreaza la lumina si nici nu se mareste la semiintuneric. Acuitatea vizuala (vederea) este brusc foarte scazuta iar tensiunea intraoculara este foarte mare. Daca pacientul nu se prezinta de urgenta la un cabinet oftalmologic, in cateva ore situatia se modifica si poate genera greseli medicale si anume :. Din cauza faptului ca ochiul ...
Ecografia este o metodă de explorare a organelor interne, cu ajutorul ultrasunetelor. Ea este neiradiantă, rapidă, repetabilă.. Ecografia glandei tiroide este metoda imagistica de prima intentie in explorarea glandei tiroide si este considerata cea mai sensibila metoda de investigare a acesteia. Explorare imagistică prin care este vizualizată glanda tiroidă, ea este o investigație care permite evaluarea dimensiunilor, structurii, vascularizației tiroidei și identificarea eventualelor chisturi sau noduli tiroidieni. Deși nu este o investigație de rutină, ecografia tiroidiană trebuie efectuată când există o suspiciune de diagnostic apărută în urmă istoricului clinic și examenului fizic.. Cum se desfasoara ecografia de tiroida?. Pacientul trebuie sa se dezbrace asa incat sa ofere medicului acces la nivelul gatului si decolteului, apoi sa se intinda pe spate, cu capul in extensie. Este intrebuintata o sonda de 7-15 MHz , care se aplica pe pielea pacientului, folosindu-se un gel ...
Insa cea mai buna metoda de a ne feri de astfel de pericole este evitarea expunerii la soare in orele amiezii, atunci cand puterea ultravioletelor este la intensitate maxima. Arsurile sunt efectele expunerii pielii la soare. De fapt, Jonas și tumoarea sa erau la fel de diferiți unul de celălalt cum sunteţi voi de persoana de alături.
View mouse Macrod2 Chr2:140395309-142392966 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
Principala acuzatie impotriva acestor oameni este anormalitatea. Desigur, se poate vedea de la o posta ca relatiile sexuale intre 2 oameni de acelasi sex nu sunt normale. Organele cu care ei improvizeaza acuplarea nu au biologic un rol specific sexului. Si totusi o astfel de imputare mi se pare absurda. Daca nu aceste relatii nu sunt normale asta nu inseamna ca ar fi benigne sau daunatoare. Apoi, recursul la normalitate nu trebuie sa fie un criteriu pentru „corectare daca aceasta anormalitate nu afecteaza negativ si vizibil libertatile altor oameni sau mediul. Fiecare om trebuie sa aiba dreptul sa isi traiasca viata asa cum isi doreste. Dupa 3000 de ani de mutilare spirituala in civilizatia occidentala, a invoca normalitatea este pueril. Anormala este insasi viata sexuala a cuplurilor „normale, asa cum o stie fiecare. Pentru ca, daca rolul sexului este reproducerea, atunci cea mai mare parte a activitatii sexuale umane este anormala din moment ce nu se finalizeaza cu reproducere. Cei mai ...
Varice Varicele sau boala varicoasa - este boala cea mai frecventa a venelor si se caracterizeaza prin dilatari segmentare pe trunchiuri venoase mai mari sau cu aspect reticulat la venele mai mici. Cand sunt situate superficial, aceste vene devin vizibile, dilatate si Generalitati Tromboza venoasa profunda este reprezentata de formarea unui cheag de sange tromb in venele profunde ale http://blogelescorpion.co/varice-ale-pelvisului-femeilor-gravide.php inferioare, pelvisului sau membrele superioare.. Trombii se tratament sanatoriu tromboflebită forma fie la nivelul venelor http://blogelescorpion.co/varice-ale-semnelor-extremiti-inferioare-1.php tratament sanatoriu tromboflebită se numeste tratament sanatoriu tromboflebită Generalitati Flebita este o afectiune caracterizata prin inflamatia unei vene care poate provoca dureri si umflaturi. Tratament sanatoriu tromboflebită cand inflamatia este cauzata de prezenta unui cheag de sange sau de continue reading, conditia poarta denumirea de ...
Culoarea anului este verdele Greenery - Pantone 15-0343TCX . Acesta simbolizeaza un nou inceput, regenerare si reconectarea cu natura. Nuanta anului Greenery o regasim in natura, de exemplu in culoarea merelor verzi, a frunzelor de iarba etc. Orice element de design care ne sugereaza sau reda natura este binevenit in amenajari. Verdele, regasit fie in piese de mobilier, tesaturi organice sau tapet, este bine pus in valoare de elemnete metalice, regasite in corpuri de iluminat cu finisaje de cupru argintii, aurii, etc ...
Am stat de vorbe cu un militian care fara ezitare a spus ca cel ce a facut asta-chestia cu teata/tepele este pasibil de amenda penala fiind o infractiune. Daca proprietate este ingradita sau sunt puse placute ce atentioneaza ca este Apropitar careva pe teren/padure NU AI CE CAUTA ACOLO .Clar ...
Am stat de vorbe cu un militian care fara ezitare a spus ca cel ce a facut asta-chestia cu teata/tepele este pasibil de amenda penala fiind o infractiune. Daca proprietate este ingradita sau sunt puse placute ce atentioneaza ca este Apropitar careva pe teren/padure NU AI CE CAUTA ACOLO .Clar ...
Zinforo este un antibiotic. Ce este Zinforo? Zinforo este o pulbere care se reconstituie intr-o solutie perfuzabila (picurare in vena). Acesta contine substanta
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Slim Fit: slabire sigura cu cetona de zmeura, Supliment alimentar, foarte eficient, creat special pentru a induce pierderea in greutate. Slim Fit actioneaza si mai rapid daca este asociat cu un regim minim de exercitiu fizic, chiar si daca acesta este de doar la 10-15 minute de mers pe jos., Cura de slabire
Orice recomandare medicala continuta de acest material are scop informativ. Este timpul ca, odata cu venirea primaverii, sa ne modificam substantial alimentatia, care trebuie sa se bazeze in primul rand pe legume si verdeturi proaspete, specifice meniuri detoxifiere anotimp. Deşi este indicat să te îmbraci gros şi să transpiri, uneori o doză de frig extrem poate accelera detoxifierea.
15 Oct 2015 Psoriazisul si legatura lui cu depresia - Psoriazisul este o afectiune de arbore de ceai este folosit ca un agent antiinflamator, ce poate ajuta.
In ultimii ani numeroase firme vin cu oferte de calificare profesionala in aproape toate domeniile de activitate. Multe dintre aceste firme se orienteaza in piata urmarind necesarul acesteia. Piata este practic barometrul care indica cererea si modifica in continuu oferta.. Cand va pregatiti pentru un interviu de angajare trebuie sa stiti ca in primul si in primul rand conteaza daca aveti o calificare in domeniul respectiv. Dupa aceea, vin si celelalte elemente legate de profesionalism, seriozitate, salarizare, etc. Degeaba un angajat da dovada de seriozitate, daca el nu are o calificare in domeniul in care lucreaza si ceea ce face este neprofesionist.. ...
Stroe a crit:Noua de ce nu ne faceti fisa ? Intreaba-l pe dr Dumitrescu sau profesorul K, ei este bulibasele homeopatiei, noi fraierii .
Telefonul ZTE Axon 7 mini este un teefon simpatic, varianta mai mica a lui Axon 7. Design-ul telefonului este bine definit, spatele arata absolut impresionant. Componentele asemenea lui Axon 7 sunt unele foarte bune, astfel ca si performantele trebuie sa fie pe masura.
Ficatul este un organ situat în partea dreaptǎ sus a abdomenului şi este parte a tubului digestiv. Are mai multe funcţii vitale: el proceseaza nutrien...
Domeniu de aplicare. Filtru de purificare a apei Aquator Economy este destinat filtrarii apei reci privenite din reteaua publica pentru imbunatatirea gustului si mirosurilor neplacute pastrand componentele naturale ale acesteia: oxigenul si sarurile minerale.. Este interzisa trecerea apei calde prin filtru.. Caracteristici constructive. ...
Uterul este un organ în formǎ de parǎ din sistemul de reproducere feminin. Este un organ ce gǎzduieşte şi protejeazǎ dezvoltarea fǎtului în timpul sar...
In cazul metastazelor multiple tratamentul este in primul rand chimioterapic. Concluzii Virusul papiloma uman este responsabil de aproximativ o treime dintre cancerele induse de un agent infecţios. Citește și Radiatiile solare, fumul de tigara sau chimicalele din atmosfera ne pot modifica genele.
Copa Holdings (CPA) has seen solid earnings estimate revision activity over the past month, and belongs to a strong industry as well.
Fitzuica București te invită la prima serie de workshop-uri din cadrul programului de dezvoltare profesionala si personala pentru studenti. Va asteptam alături de noi si de invitații nostri, oameni de afaceri cu experiență și succes in antreprenoriat in SUA. Vino sa descoperi impreună cu Fitzuica ce înseamnă să fii un antreprenor si un salesman eficient, ce calități sunt necesare și care sunt pasii prin care poți să ajungi acolo. Costul seminariilor este sponsorizat în întregime de Fitzuica.. ...
Distribuitorul independent menţionat mai înainte este singurul responsabil de conţinutul acestui site, iar Reţeaua CaliVita® International şi entităţile sale operatoare nu au nicio responsabilitate cu privire la acest site.. ...
Amfotericina b este utlizat in principal la pacientii cu infectii fungice progresive si posibil fatale.Parenteral:infectii fungice invazive
✅ Endocrinologie Galati - Centrul medical Pro-Clinic - Endocrinolog Galati - Este o ramură a medicinei care se ocupă cu diagnosticarea și tratamentul ...
Cumpara rapid si simplu Hepato Vital. Hepato Vital cu Silimarina este considerat un complex de flavonoide, compusa din silibina, silidianina si silicristina.
Un nou studiu clinic adresat celor cu o boala avansata loco-regional sau metastatica care au beneficiat de o prima linie de tratament citostatic pe baza de saruri de platina, la care boala este actual in reluare de ...
Invaziv - Dictionar termeni medicali - Cu caracter de invazie, agresivitate. O procedura medicala este invaziva, daca realizarea ei presupune lezare tisulara sau un disconfort fizic semnificativ
Suflu - Dictionar termeni medicali - Zgomot auzit la auscultatie, asemanand cu sunetul pe care il produce aerul care iese dintr-un burduf. Un suflu este produs prin accelerarea sau prin incetinirea brusca a circulatiei unui fluid. Diferite
Piata de factoring a inregistrat o crestere de 15,5% in primele sase luni ale anului, comparativ cu aceeasi perioada a lui 2015. Aceasta este...
Cumpara rapid si simplu Naut Solaris. Naut Solaris este un produs natural, ce poate fi folosit ca ingredient in diverse preparate gustoase.
5.B.11. The One Electron Transmembrane Transfer Complex (TmcABCD) Family Pereira et al. 2006 reported that three membrane-bound redox complexes are present in Desulfovibrio spp., whose genes are not found in the genomes of other sulfate reducers such as Desulfotalea psycrophila and Archaeoglobus fulgidus. These complexes contain a periplasmic cytochrome c subunit of the cytochrome c3 family, and their presence in these organisms correlates with the presence of a pool of periplasmic cytochromes c3, also absent in the two other sulfate reducers. Pereira et al. 2006 isolated and characterized the first of such complexes, Tmc from D. vulgaris Hildenborough, which is associated with the tetraheme type II cytochrome c3. The isolated Tmc complex contains four dissimilar subunits, including the small TpIIc3 (TmcA), an integral membrane cytochrome b (TmcC), and two cytoplasmic proteins, an iron-sulfur protein (TmcB) and a tryptophan-rich protein (TmcD). Spectroscopic studies indicated the presence of ...
Archaeoglobus fulgidus Methanococcus jannaschii Methanobacterium thermoautotrophicum Pyrococcus horikoshii Saccharomyces cerevisiae Caenorhabditis elegans Aquifex aeolicus Synechoscystis Escheria coli Bacillus subtilis Mycobacterium tuberculosis Haemophilus influenzae Helicobacter pylori Mycoplasma genitalium Mycoplasma pneumoniae Borrelia burgdorferi Treponema pallidum Chlamydia trachomatis Chlamydia pneumoniae Rickettsia prowazekii ...
The H+-translocating F420H2 Dehydrogenase (F420H2DH) Family (TC# 3.D.9) is a member of the Na+ transporting Mrp superfamily. A single F420H2 dehydrogenase (also referred to as F420H2:quinol oxidoreductase) from the methanogenic archaeon, Methanosarcina mazei Gö1, has been shown to be a redox driven proton pump. The F420H2DH of M. mazei has a molecular size of about 120 kDa and contains Fe-S clusters and FAD. A similar five-subunit enzyme has been isolated from Methanolobus tindarius. The sulfate-reducing Archaeoglobus fulgidus (and several other archaea) also have this enzyme. Reduction of 2-hydroxyphenazine by F420H2DH is accompanied by the translocation of 1 H+ per 2 electrons transferred. The overall vectorial reaction catalyzed by F420H2DH is Reduced donor (2e−) + H+ (in) ⇌ oxidized acceptor (2e−) + H+ (out) Methanomassiliicoccus luminyensis has been isolated from the human gut and requires H2 and methanol or methylamines to produce methane. The organism lacks cytochromes, indicating ...
O-phospho-L-serine---tRNA ligase ( EC 6.1.1.27 , O-phosphoseryl-tRNA ligase, non-canonical O-phosphoseryl-tRNA synthetase, SepRS) is an enzyme with systematic name O-phospho-L-serine:tRNACys ligase (AMP-forming). This enzyme catalyses the following chemical reaction : In organisms like Archaeoglobus fulgidus , this enzyme ligates O-phosphoserine to tRNACys. References Fukunaga, R.; Yokoyama, S. (2007).
Numerous significant hits using gapped BLAST to naphthoate synthase from H. parahaemolyticus (1086070), H. influenzae (1170915), E. coli (126968), Synechocystis sp. (7428382), among others. Also many hits to putative enoyl-CoA hydratase/isomerase from Arabidopsis thaliana (2462733), Archaeoglobus fulgidus (7428375), and to crotonase from Thermoanaerobacterium thermosaccharolyticum (1903327), among others ...
Three-dimensional structure of AprB from A. fulgidus (A, B) and selected, homology modeling-based AprB models from Allochromatium vinosum (C, D), Pelagibacter u
The origin of microorganisms in oil reservoirs has been the subject of much interest in the last decades; scientists have provided evidence of active microbial communities in situ since the 1920s. Members of the genus Archaeoglobus are hyperthermophiles and obtain energy by reducing oxidized sulfur compounds to H2S. Archaeoglobus species, because of their ability to reduce sulfate, may be important contributors of biogenic H2S generation in high-temperature oil fields. A number of pure cultures of methanogenic Archaea classified in different taxonomic groups have been isolated from oil deposits. Isolation of methanogens has been successful from slightly saline to saline oil well waters in the mesophilic range of temperatures. The parallel analysis of high-temperature enrichment cultures from the formation waters of four oil fields showed that contrary to the Thermococcales, none of the methanogens recovered from the culture-independent analysis were obtained in cultures. Low-temperature oil reservoirs
Era vorba despre discriminarea pozitiva si practica institutiilor de invatamant superior americane de a avea un anumit numar de locuri rezervate pentru minoritatile nu socio-economice, cum s-ar zice din replyul tau de mai sus, ci rasiale. Ma revoltam impotriva acestui sistem si eram de parere ca admiterea ar trebui sa se faca pe baza rezultatelor academice, in mod complet colour-blind. Pozitia ta era, ca si acuma, ca este vorba despre protectia minoritatilor socio-economice si nu rasiale. Desigur, asta ridica intrebarea de ce sistemul este asa cum este si locurile sunt rezervate pentru minoritatile hispanica, neagra si care or mai fi (nu cred ca se tine cont de starea materiala - !), in loc sa fie rezervate doar pentru persoanele cu o stare socio-economica definita independent de culoare (impotriva acestui din urma sistem nu as ridica nicio obiectie). Intrucat explicatia ta nu era, in mod evident, suficienta, am propus ca sistemul se datoreaza, in realitate, rezultatelor academice inferioare ale ...
Sindromul rezistentei la glucocorticoizi este cauzat de mutațiile genei receptorului pentru glucocorticoizi si se caracterizează printr-o cantitate de cortizol seric si urinar care depaseste cu mult valorile normale fara ca sa apară caracteristicile fenotipice ale sindromului Cushing(retenție de apa in țesuturi, tendința de ingrasare, topirea musculaturii).. Rezistenta la cortizol este in toate cazurile parțiala, mutațiile in forma homozigota care fac ca gena receptorului pentru glucocorticoizi sa fie total nefuncționala fiind letale. Gena receptorului pentru glucocorticoizi este situata pe cromozomul 5(locusul 5q31-q32) si conține 9 exoni. Daca aceasta gena este mutanta organismul este rezistent la cortizol si printr-un mecanism de feedback glandele suprarenale secreta cantitati mult mai mari nu numai de cortizol dar si de androgeni(DHEA, DHEAS). Din acest punct de vedere acest sindrom seamănă foarte mult cu hiperplaziile adrenale numai ca aici deficienta nu este legata de secreția ...
Streaming STAR-686 Masami Ichikawa Erogenous Este × Full Course 10 Corner 240 Minutes SP, Download STAR-686 Masami Ichikawa Erogenous Este × Full Course 10 Corner 240 Minutes SP - JavPlay
Read about uniQure, which plans preclinical studies that could lead to clinical testing of its gene therapy, AMT-130, in patients with Huntingtons disease.
Dragi colisteni, si colegi de dezbateri, faptul ca sunt din schema MCC in acest caz este irelevant - caci ma pronunt exclusiv ca o persoana privata, ca un actor al scenei artistice, al celei vizuale in speta. Interesant este sa vedem, totusi, ce ne ofera in materie de politica culturala acest MCC al nostru. O schema macar a ceea ce se doreste a se face in materie de conservare, sustinere si promovare a culturii romanesti pe plan intern si extern. Este clar ca acum cultura nu este o prioritate a Romaniei (cind o fi fost oare???). Si mai relevant este sa se pronunte cit mai clar in aceste chestiuni de maxima importanta, caci daca aflam ca exista profesiunea de negociator in probleme de ostateci, aseara am auzit vorbind la televizor cel putin doi dintre ei, de ce sa nu existe si niste strategi in probleme de politica culturala? Consider ca ar fi mult mai relevant sa le aflam lor parerea, ideile, si mai productiva ar fi analiza acestora, decit sa ne dam noi cu presupusul cum, cit si mai ales in ce ...
Este important să ştim şi să ne aducem aminte că un adevărat creştin ortodox nu este cel care doar primeşte în mod formal dogmele Ortodoxiei, ci cel care - precum învăţa atât de frumos marele nostru ierarh rus, Sfântul Tihon de Zadonsk - cugetă în chip ortodox, simte în chip ortodox şi trăieşte în chip ortodox, întruchipând duhul Ortodoxiei în viaţa sa.. Acest duh de asceză şi lepădare de cele lumeşti, aşa cum este zugrăvit cu limpezime de Cuvântul lui Dumnezeu şi în scrierile Sfinţilor Părinţi, este cel mai aspru şi cu îndrăzneală respins de modernişti, neo-ortodocşi, care vor să ţină pasul cu duhul acestei lumi care zace în rău, al cărui stăpânitor, după cuvintele Domnului, nu este altul decât diavolul (potrivit Ioan 12, 31). Astfel, ei nu vor să-I placă lui Dumnezeu, ci stăpânitorului acestei lumi, diavolul; şi, prin urmare, ei încetează de a fi adevăraţi creştini ortodocşi, chiar dacă se numesc pe ei înşişi ...
Este o boala care este benigna, provocata in cele mai multe cazuri de un parazit numit Demodex. Se caracterizeaza prin aparitia unor scuame (pelicule, cojite) la baza genelor, asemanatoare cu matreata din par. Apare frecvent pe un teren seboreic (la cei predispusi la matreata). Nu influenteaza in nici un fel vederea dar poate da o senzatie neplacuta de greutate, de disconfort la nivelul pleoapelor. In plus, aspectul este foarte inestetic, mai ales ca aceste cojite se refac de la o zi la alta in perioadele acute. Tratamentul este relativ simplu. Cel care a dat cele mai bune rezultate este urmatorul : Read the rest of this entry ». ...
Bronhodilatatoare: medicatia centrala pe simptome; administrate la nevoie pentru a diminua simptomele intermitente sau accentuate si administrate regulat pentru prevenirea si reducerea simptomelor persistente; alegerea intre beta2-agonisti, anticolinergice, metilxantine si terapie asociata depinde de disponibilitatea medicatiei si raspunsul individual exprimat prin gradul de reducere a simptomelor si aparitia reactiilor adverse; tratamentul regulat cu beta2-agonsti de lunga durata este mai eficient si cinvenabil decat tratamentul cu beta2-agonisti de scurta durata, dar mai scump; combinatiile de droguri cu mecanisme diferite de actiune si durata de actiune pot creste gradul de bronhodilatatie cu efecte adverse mai putine; teofilina este efcace in BPOC, dar datorita potentialei toxicitati sunt preferati beta2-agonistii inhalatori cand sunt disponibili; terapia regulata cu bronhodilatatori nebulizati pentru un pacient stabil nu este potrivita decat daca este demonstrata eficacitatea mai buna ca ...
Acest lucru este mai ales adevărat în cazul personelor lipsite de un suport social [23]. Am J Gastroenterol. Există argumente pro şi contra recomandării începerii screeningului la 45 de ani.
Articole Sanatate si Anatomie. Parazitii intestinali la caini. Subiect: Parazitii intestinali la caini. Treci in modul hibrid. Treci in modul pe subiecte. Infestarea cu paraziti intestinali este foarte des intalnita la caini, iar puii cum de a vindeca viermi câine mai vulnerabili decat adultii la astfel de afectiuni.. Este foarte important sa tratati aceste cum de a vindeca viermi câine cu paraziti ale cainilor dumneavoastra din urmatoarele motive:. Infestarea cu paraziti este daunatoare sanatatii animalului si o infestare masiva poate fi chiar fatala. Parazitii intestinali pot fi transmisi si omului, cauzand diferite probleme de sanatate! Copiii sunt de asemenea mai expusi decat adultii. Astfel, va trebui sa aveti grija sa va deparazitati regulat cainele de companie! Sfatuiti-va cu veterinarul in ceea ce priveste schema de deparazitare necesara pentru catelul dumneavoastra.. Cauze ale infestarii cu paraziti intestinali Tipuri de paraziti intestinali. Viermii rotunzi sunt printre cel mai des ...
Continuance este un nou concept realizat de un grup de designeri din, deloc surprinz?tor, China. Ace?tia au proiectat baterii de tipul AA care prezint? un port USB.. Se presupune c? bateriile sunt reînc?rcabile ?i pot înc?rca orice dispozitiv care se pot înc?rca prin USB. Dac? st?m s? ne gândim, aproape orice dispozitiv prezint? astfel de muf? în aceste zile. Bateriile ar fi perfecte pentru a înc?rca telefoanele mobile, consolele de jocuri, camere foto, GPS-uri sau chiar ?i tabletele.. Chiar dac? este doar un concept, se pare c? este unul foarte comod ?i practic, pe care to?i pasiona?ii de tehnologie l-ar aprecia. Pute?i vedea în galeria foto pozele cu acest concept.. Ce p?rere ave?i despre aceste baterii? Cât a?i fi dispu?i s? pl?ti?i pentru o astfel de baterie?. ...
Vitiligo este o afectiune cronica, o hipomelanoza melanopenica, caracterizata de scaderea cantitatii de melanina din derm. Cauza este necunoscuta, dar se pare a fi incriminat un mecanism autoimun, cu scaderea celulelor T helper, cresterea anticorpilor dirijati impotriva melanocitelor (celulele producatoare de pigment melanic, ce lipsesc complet) sau chiar un stress major, gen soc emotional. intr-o proportie de 30-40% se poate mosteni familial.. Se manifesta prin aparitia la nivelul fantelor palpebrale, peribucal, organe genitale sau extremitati a unor placi alb-sidefii, bine delimitate, cu contururi neregulate, iar la periferie prezinta o zona mai inchisa la culoare, hiperpigmentata. Afectiunea apare mai frecvent la copiii de varsta scolara, adolescenti si adultii tineri. Uneori, placile acromice pot conflua, iar vitiligo devine generalizat sau chiar universal, cu depigmentarea completa a pielii si parului.. Evolutia este nedefinita, fiind mai favorabila la copii decat la adulti. Rar se produc ...
ValoareFactura, NrNIR, DataNIR, CodProdusRecepţionat, CantitateRecepţionată, PreţProdusRecepţionat, ValoareNIR, CodGestiune, DenumireGestiune, LocalizareGestiune Reguli de gestiune 1. O factura este primita de la un singur furnizor 2. Pe o factură apar mai multe produse 3. Un NIR este întocmit pentru o singură factură, pentru o factură se pot întocmi mai multe NIR-uri 4. Pe un NIR se recepţionează mai multe produse 5. Un NIR se intocmeşte pentru o singură gestiune 6. Pretul receptionat este intotdeauna acelasi cu pretul facturat Cerinţe: Determinaţi modelul relaţional utilizând procedeul nornalizării Implementaţi modelul astfel obţinut în Microsoft Access. Stabilirea dictionarului de date (eliminarea atributelor sinonime si calculabile) Se eliminina CodProdusFacturat, CodProdusRecepţionat fiind sinonime ale atributului CodProdus Se elimina PreţProdusRecepţionat (sinonim al PretProdusFacturat) Se elimina ValoareFactura, ValoareNIR Dictionarul de date: CodProdus, ...
Localizarile obisnuite sunt fata anterioara a genunchiului si spatele. Totusi, psoriazisul se mai poate localiza fie in pliurile psoriazis cupru inghinale sau axilare, fie psoriazis cupru nivelul palmei sau ale suprafetelor plantare; in acest ultim caz, psoriazisul ia forma mai curand hiperkeratozica piele uscata, aspra, cenusie, fisurata.. O alta localizare frecventa este la nivelul parului capului, firele de par traversand placile fara sa Informatii generale Psoriazisul este o boala cronica, mediata imunologic, care consta din supra-producerea psoriazis cupru celule keratinocite care formeaza la suprafata pielii placile psoriazice, placi rosii, acoperite cu scuame coji solzoase ce pot fi pruriginoase provoaca mancarimi sau pot sangera.. Etiopatogenie Psoriazisul in placi este o psoriazis cupru cutanata cronica, mediata imunologic, inflamatorie, de etiologie necunoscuta. Placile psoriazice sunt caracterizate prin infiltrarea de celule T ce produc citokine inflamatorii. Citokinele, interleukina ...
Informaţii generale CK-MB este fracţiunea miocardică a creatinkinazei asociată cu infarctul miocardic. Este utilă pentru a estima mărimea zonei de necroză1. Recomandări pentru determinarea CK-MB Pentru stabilirea valorilor bazale ale enzimei este necesară recoltarea probei pacientului la debutul bolii, după care se va
El objetivo de este artículo es ilustrar las técnicas y los conceptos básicos de la Teoría de la Decisión. Para lograr este objetivo se ha adoptado el problema tipo quizá más sencillo: el problema de la inversión. Este ...
Este poate cel mai popular site de rezervare a camerelor de hotel. Odata cu revolutia aplicatiilor mobile a aparut si aplicatia cu acelasi nume. Functionalitatea aplicatiei o mimeaza foarte bine pe cea a site-ului, utilizatorii avand posibilitatea sa caute hoteluri in functie de pret, zona, sa consulte galeriile foto si parerile altor utilizatori, precum si sa adauge filtre de cautare, precum WiFi sau posibilitatea de a te caza impreuna cu un animal de companie.. Aplicatia se bucura de mii de unitati de cazare verificate atat de catre Booking.com, cat si de parerile utilizatorilor. Binenteles ca aplicatia este gratuita si poate fi descarcata de aici.. ...
Regleaza tranzitul intestinal Meridian Intestin Gros este un amestec de pulberi din 17 plante medicinale, cu rol de reglare a functiei intestinului gros. Meridianul Intestin Gros, atunci cand este echilibrat energetic, contribuie la mentinerea in stare optima a digestiei, dar ne ofera si capacitatea de a ne adapta la situatiile noi pe care ni le ofera ...
Frumusetea parului este direct proportionala cu grija pe care i-o dedicam. Un par frumos este un par sanatos. Principalele probleme care pot afecta gr...
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De ceva timp am inceput sa ma interesez care este cel mai curat sampon si gel de dus pentru bebelusi, Ca si in cazul servetelelor umede, am fost foarte atenta la lista de ingrediente si mi-am facut un top al sampoanelor si gelurilor de dus. Lista de ingrediente este foarte importanta, dar imi doresc sa…
Cum sa cumperi Winstrol în Canada legal pentru culturism? Puteţi obţine o reţetă? Poti cumpara din piata neagra? Care sunt preţurile steroizi?
Este artigo foi escrito por JIPS em 23 de julho de 2009 às 5:17, e está arquivado em Devocional. Siga quaisquer respostas a este artigo através do RSS 2.0. Você pode deixar uma resposta ou fazer um trackback do seu próprio site ...
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Localitatea este accesibila pe DN 12 sau pe linia CF 400 Bucuresti-Deda ; Baile Tusnad, Judetul Harghita, Romania; - Este amplasata aproape de soseaua principala si de centrul orasului ...
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Gabrielle Chanel este cu siguranta in aceasta perioada cel mai comentat si comunicat parfum. Dupa atatea flankere pentru Chanel 5, toata lumea a asteptat un Chanel nou. Ceva complet nou. Comunicarea a fost bine gandita, cu mult teasing. Pasionatii de parfumuri s-au agitat teribil sa gaseasca primele mostre, primele exemplare iesite la vanzare. Am cautat si eu pe eBay primele mostre si decanturi, dar nu m-am agitat foarte tare. Am asteptat sa apara parerile pasionatilor de parfum. Sunt inclusa in […]. ...
Invidia este a mea trasura cu aer burghez ce ma insoteste in fiecare dimineata de duminica catre cimitirul vesel al nazuintelor de viitor-aminte ...
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Archaeoglobus fulgidus (370 aas; gbAE001071), Methanobacterium thermoautotrophicum (365 aas; gbAE000865) and Synechocystis (383 ...
... and the archaeon Archaeoglobus fulgidus. With the exception of A. fulgidus, all known microbes that grow via perchlorate ...
Archaeoglobus fulgidus. *Methanococcus jannaschii. *Aeropyrum pernix. *Sulfolobus. *Methanopyrus kandleri strain 116, an ...
"Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus". Biochemistry. 49 (41): 8912-21. doi:10.1021 ...
November 1997). "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus". ... June 2010). "Complete genome sequence of Archaeoglobus profundus type strain (AV18)". Standards in Genomic Sciences. 2 (3): 327 ...
... from Archaeoglobus Fulgidus". Journal of Structural and Functional Genomics. 7 (1): 37-50. doi:10.1007/s10969-006-9008-x. PMID ...
hgcG is significantly similar to a region of the Archaeoglobus fulgidus genome. The genes were named hgcA through hgcG ("high ...
The structure of the NADK from the archaean Archaeoglobus fulgidus has been determined. In humans, the genes NADK and MNADK ... "Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP". Journal of Molecular ...
The sulfate-reducing Archaeoglobus fulgidus (and several other archaea) also have this enzyme. Reduction of 2-hydroxyphenazine ...
"Oxygen detoxification in the strict anaerobic archaeon Archaeoglobus fulgidus: superoxide scavenging by neelaredoxin". Mol. ...
February 2002). "Structure of adenylylsulfate reductase from the hyperthermophilic Archaeoglobus fulgidus at 1.6-A resolution ...
Formyl-MFR dehydrogenase was also isolated from Methanosarcina barkeri and Archaeoglobus fulgidus cell extracts. Molybdenum- ...
Hyperthermophilic sulfate-reducing archaen Archaeoglobus fulgidus has been recently reported to enable anaerobic oxidation of ... Archaeoglobus fulgidus". The ISME Journal. 8 (11): 2153-66. doi:10.1038/ismej.2014.58. PMC 4992073. PMID 24763368. Benjdia A, ... PflD is reported to be responsible for the capacity of A. fulgidus to grow on a wide range of unsaturated carbons and fatty ...
showed evidence that CRISPR repeat regions from the genome of Archaeoglobus fulgidus were transcribed into long RNA molecules ... 2002). "Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus". Proc Natl Acad ...
Archaeoglobus fulgidus MDR1 (troR), a metal-dependent transcriptional repressor, which negatively regulates its own ...
Ftr from the mesophilic methanogen Methanosarcina barkeri and the sulphate-reducing archaeon Archaeoglobus fulgidus have a ...
"The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A". ...
... from Archaeoglobus fulgidus. Atomic-resolution structures of three other bacterial importers, E. coli BtuCD, E. coli maltose ...
... with two members in Archaeoglobus fulgidus. They are related to UbiD, a 3-octaprenyl-4-hydroxybenzoate carboxy-lyase from ...
Cys-tRNA synthase from Archaeoglobus fulgidus". Journal of Molecular Biology. 370 (1): 128-41. doi:10.1016/j.jmb.2007.04.050. ...
... gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases". Journal of ...
In the Archaeoglobus fulgidus CopA (TC# 3.A.3.5.7), invariant residues in helixes 6, 7 and 8 form two transmembrane metal ... The delivery of Cu+ by Archaeoglobus fulgidus Cu+-chaperone, CopZ (see TC# 3.A.3.5.7), to the corresponding Cu+-ATPase, CopA ( ... 2008) have determined structures of two constructs of the Cu (CopA) pump from Archaeoglobus fulgidus by cryoelectron microscopy ...
... archaeoglobus MeSH B07.200.080.080.100 - archaeoglobus fulgidus MeSH B07.200.400.400 - halobacteriaceae MeSH B07.200.400.400. ...
O-phospho-L-seryl-tRNACys In organisms like Archaeoglobus fulgidus, this enzyme ligates O-phosphoserine to tRNACys. Fukunaga R ...
He describes the microorganism Archaeoglobus fulgidus as an anomaly with respect to a phylogenetic tree based upon the code for ...
Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus. Proc Natl Acad Sci U S A ...
... from Bacillus subtilis Archaeal SRP RNA Archaeoglobus fulgidus Eukaryotic protist SRP RNA from Trypanosoma brucei Eukaryotic ...
Archaeoglobus fulgidus was seen as an anomaly with respect to a phylogenetic tree based upon the encoding for the enzyme HMGCoA ...
... iz Archaeoglobus fulgidus.[24] Strukture atomske-rezolucije tri druga bakterijska importera, E. coli BtuCD,[21] E. coli ...
The Archaeoglobus fulgidus genome is a circular chromosome roughly half the size of E. coli at 2,178,000 base pairs. Although ... PubMed references for Archaeoglobus PubMed Central references for Archaeoglobus Google Scholar references for Archaeoglobus See ... for Archaeoglobus Search Species2000 page for Archaeoglobus MicrobeWiki page for Archaeoglobus LPSN page for Archaeoglobus ... Archaeoglobus is a genus of the phylum Euryarchaeota. Archaeoglobus can be found in high-temperature oil fields where they may ...
showed evidence that CRISPR repeat regions from the genome of Archaeoglobus fulgidus were transcribed into long RNA molecules ...
SULFITE REDUCTASE, DISSIMILATORY-TYPE SUBUNIT ALPHASULFITE REDUCTASE, DISSIMILATORY-TYPE SUBUNIT BETAGlycerin; Propane-1,2,3-triolGlycerolIronSULFUR CLUSTERSiroheme
Genomic DNA from Archeoglobus fulgidus Strain DSM 4304 TypeStrain=True Application: Genome sequencing strain ... Archaeoglobus fulgidus Stetter (ATCC® 49558D-5™) Strain Designations: Genomic DNA from Archeoglobus fulgidus Strain DSM 4304 [ ... The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus. Nature 390: 364-370, ...
Archaeon Archaeoglobus fulgidus [TaxId: 2234] A146-297. d1m5ha2. Alpha and beta proteins (a+b) Ferredoxin-like ... Archaeon Archaeoglobus fulgidus [TaxId: 2234] B1001-1145. d1m5hb1. Alpha and beta proteins (a+b) Ferredoxin-like ... Archaeon Archaeoglobus fulgidus [TaxId: 2234] B1146-1297. d1m5hb2. Alpha and beta proteins (a+b) Ferredoxin-like ... Archaeon Archaeoglobus fulgidus [TaxId: 2234] C2001-2145. d1m5hc1. Alpha and beta proteins (a+b) Ferredoxin-like ...
Properties and primary structure of a thermostable L-malate dehydrogenase from Archaeoglobus fulgidus.. Langelandsvik AS1, ... A thermostable l-malate dehydrogenase from the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus was isolated ... A. fulgidus L-malate dehydrogenase was stable for 5 h at 90 degrees C, and the half-life at 101 degrees C was 80 min. Thus, A. ... fulgidus L-malate dehydrogenase is the most thermostable L-malate dehydrogenase characterized to date. Addition of K2HPO4 (1 M ...
Crystal structures of a novel ferric reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus and its complex with ... Archaeon Archaeoglobus fulgidus [TaxId: 2234] B. d1i0rb_. All beta proteins Split barrel-like FMN-binding split barrel NADH:FMN ...
... Daniel B. ... A,B) Slices from 3D tomograms reconstructed from cryoET tilt series of A. fulgidus whole cells in growth phase. The insets show ... Supplementary Figure S3: A. fulgidus development under varying nutritional conditions. A-E) TEM images of (A) a cell grown in ... Supplementary Figure S4: CryoEM of A. fulgidus cells after three generations of reduced or elevated phosphate conditions. A) ...
Archaeoglobus fulgidus VC-16. › Archaeoglobus fulgidus str. DSM 4304. › Archaeoglobus fulgidus str. VC-16. › Archaeoglobus ... Archaeoglobus. › Archaeoglobus fulgidus. Strains i. › ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126, ATCC 49558, DSM ... Taxonomy - Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) Basket 0 ... Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126). ...
CopA from the extreme thermophile Archaeoglobus fulgidus is a P-type ATPase that transports Cu(+) and Ag(+) and has individual ... Role of metal-binding domains of the copper pump from Archaeoglobus fulgidus Biochem Biophys Res Commun. 2006 Sep 15;348(1):124 ... CopA from the extreme thermophile Archaeoglobus fulgidus is a P-type ATPase that transports Cu(+) and Ag(+) and has individual ...
Archaeoglobus fulgidus gen. nov., sp. nov. a new taxon of extremely thermophilic Archaebacteria. Syst. Appl. Microbiol. 10:172- ... Archaeoglobus fulgidus gen. nov., sp. nov. a new taxon of extremely thermophilic Archaebacteria. Syst. Appl. Microbiol. 10:172- ... WoRMS (2018). Archaeoglobus fulgidus Stetter, 1988. Accessed at: http://www.marinespecies.org/aphia.php?p=taxdetails&id=573342 ...
Assessment of the Carbon Monoxide Metabolism of the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus VC-16 by ...
sp,O28608,ALADH_ARCFU Alanine dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC ... Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126). ... Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) ... cellular organisms › Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus › ...
We determined the crystal structure of the enzyme from the sulfate-reducing archaeon Archaeoglobus fulgidus at 2-Å resolution ... We determined the crystal structure of the enzyme from the sulfate-reducing archaeon Archaeoglobus fulgidus at 2-Å resolution ... Structure of the Dissimilatory Sulfite Reductase from the Hyperthermophilic Archaeon Archaeoglobus fulgidus. * Home ... Structure of the Dissimilatory Sulfite Reductase from the Hyperthermophilic Archaeon Archaeoglobus fulgidus. Publikationstyp:. ...
Archaeoglobus fulgidus Stetter (ATCC® 49558™) ATCC® Number: 49558™ Strain Designations: DSM 4304 [ATCC 49203] ...
Archaeoglobus fulgidus Stetter (ATCC® 49558D-5™) ATCC® Number: 49558D-5™ Strain Designations: Genomic DNA from Archeoglobus ... Archaeoglobus fulgidus Stetter (ATCC® 49558™) ATCC® Number: 49558™ Strain Designations: DSM 4304 [ATCC 49203] ...
... reductase from the extremely thermophilic sulphate-reducing archaeon Archaeoglobus fulgidus is an iron-sulphur flavoprotein ... Keyword(s): adenylylsulphate reductase , Archaeoglobus fulgidus , dissimilatory sulphate reduction , flavoprotein and iron- ... Adenylylsulphate reductase from the sulphate-reducing archaeon Archaeoglobus fulgidus: cloning and characterization of the ... reductase from the extremely thermophilic sulphate-reducing archaeon Archaeoglobus fulgidus is an iron-sulphur flavoprotein ...
Erratum: The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus *Hans-Peter ... The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus *Hans-Peter Klenk ... Archaeoglobus fulgidus,/i, . Opens in a new window. ... Archaeoglobus fulgidus,/i, . Opens in a new window. ...
Role of SRP19 in assembly of the Archaeoglobus fulgidus signal recognition particle.. ... sulfate-reducing archaeon Archaeoglobus fulgidis. A combination of native gel mobility shift, filter binding, and Ni-NTA ...
Archaeoglobus fulgidus. *Methanococcus jannaschii. *Aeropyrum pernix. *Sulfolobus. *Methanopyrus kandleri strain 116, an ...
Structure of GlnK1, a signalling protein from Archaeoglobus fulgidus. C. Litz, S. Helfmann, S. Gerhardt and S. L. A. Andrade ... The structure of GlnK1, one of three GlnK proteins encoded by the hyperthermophilic archaeon A. fulgidus, was solved to 2.28 Å ...
Discovery and Characterization of Iron Sulfide and Polyphosphate Bodies Coexisting in Archaeoglobus fulgidus Cells. . ... Discovery and Characterization of Iron Sulfide and Polyphosphate Bodies Coexisting in Archaeoglobus fulgidus Cells - Descarga ... Discovery and Characterization of Iron Sulfide and Polyphosphate Bodies Coexisting in Archaeoglobus fulgidus Cells. ... Archaeoglobus fulgidus strain VC16, a hyperthermophilic, anaerobic, and sulfate-reducing microorganism. Dense granules were ...
Fingerprint Dive into the research topics of Structure of the ATP binding domain from the Archaeoglobus fulgidus Cu ,sup,+,/ ... Structure of the ATP binding domain from the Archaeoglobus fulgidus Cu +-ATPase. ...
The hyperthermophilic archaeon Archaeoglobus fulgidus strain 7324 has been shown to grow on starch and sulfate and thus ... Archaeoglobus fulgidus, starch degradation, cyclodextrin glucanotransferase. Research affiliation:. OceanRep , GEOMAR , FB3 ... Unusual starch degradation pathway via cyclodextrins in the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus ... Unusual starch degradation pathway via cyclodextrins in the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus ...
CRYSTAL STRUCTURE OF FERRITIN E65R MUTANT FROM HYPERTHERMOPHILIC ARCHAEON ARCHAEOGLOBUS FULGIDUS , 5V5K ... ARCHAEOGLOBUS FULGIDUS --. 5V5K_A. O29424 --. ESCHERICHIA COLI. ARCHAEOGLOBUS FULGIDUS --. 5V5K_E. O29424 --. ESCHERICHIA COLI ... ARCHAEOGLOBUS FULGIDUS --. 5V5K_G. O29424 --. ESCHERICHIA COLI. ARCHAEOGLOBUS FULGIDUS --. 5V5K_B. O29424 --. ESCHERICHIA COLI ... ARCHAEOGLOBUS FULGIDUS --. 5V5K_C. O29424 --. ESCHERICHIA COLI. ARCHAEOGLOBUS FULGIDUS --. 5V5K_H. O29424 --. ESCHERICHIA COLI ...
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126). Loading... ...
Archaeoglobus fulgidus Cys. Cysteine. CR. Caloric restriction. CRTC2. CREB-regulated transcription coactivator 2 ...
Archaeoglobus fulgidus. Klenk et al., Nature 390:364-370 (1997). Borrelia burgdorferi. Fraser er al., Nature 390:580-586 (1997) ...
Crystallization and preliminary X-ray analysis of adenylylsulfate reductase from Archaeoglobus fulgidus. ... Adenylylsulfate reductase from A. fulgidus was purified and crystallized under anaerobic conditions. X-ray diffraction ...
CRYSTAL STRUCTURES OF A NOVEL OPEN PORE FERRITIN FROM THE HYPERTHERMOPHILIC ARCHAEON ARCHAEOGLOBUS FULGIDUS , 1S3Q ... CRYSTAL STRUCTURES OF A NOVEL OPEN PORE FERRITIN FROM THE HYPERTHERMOPHILIC ARCHAEON ARCHAEOGLOBUS FULGIDUS ...
From Archaeoglobus Fulgidus At 2.16 A Resolution Complexed With Citrate ... The binding sites of Zinc atom in the structure of Crystal Structure of Archaemetzincin (Amza) From Archaeoglobus Fulgidus At ... Zinc in the structure of Crystal Structure of Archaemetzincin (Amza) From Archaeoglobus Fulgidus At 2.16 A Resolution Complexed ...
Archaeoglobus fulgidus (70), Pyrococcus horikoshii (71) and Aeropyrum pernix (72), but one or two FKBPs. Hyperthermophilic ... sulphate-reducing archaeon Archaeoglobus fulgidus. Nature 390, 364-370 (1997) 71. Kawarabayasi, Y., M. Sawada, H. Horikawa, Y. ... fulgidus (70), P. horikoshii (71), and Aeropyrum pernix (72). We isolated genes encoding a short-type FKBP from Methanococcus ... fulgidus, also exhibited little PPIase activity (Ideno et al. unpublished data). One of two consensus FKBP motifs in PROSITE ...
  • Whereas the protein-based memristor devices in the previous work were fabricated from the commercial horse spleen ferritin, the new work uses the unique high iron loading capacity of Archaeoglobus fulgidus ferritin (AfFtn). (frogheart.ca)