Aqueous Humor: The clear, watery fluid which fills the anterior and posterior chambers of the eye. It has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens. (Cline et al., Dictionary of Visual Science, 4th ed, p319)Wit and Humor as Topic: The faculty of expressing the amusing, clever, or comical or the keen perception and cleverly apt expression of connections between ideas that awaken amusement and pleasure. (From Random House Unabridged Dictionary, 2d ed)Trabecular Meshwork: A porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates to the canal of Schlemm.Ciliary Body: A ring of tissue extending from the scleral spur to the ora serrata of the RETINA. It consists of the uveal portion and the epithelial portion. The ciliary muscle is in the uveal portion and the ciliary processes are in the epithelial portion.Fluorophotometry: Measurement of light given off by fluorescein in order to assess the integrity of various ocular barriers. The method is used to investigate the blood-aqueous barrier, blood-retinal barrier, aqueous flow measurements, corneal endothelial permeability, and tear flow dynamics.Intraocular Pressure: The pressure of the fluids in the eye.Iris: The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.Anterior Chamber: The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)Vitreous Body: The transparent, semigelatinous substance that fills the cavity behind the CRYSTALLINE LENS of the EYE and in front of the RETINA. It is contained in a thin hyaloid membrane and forms about four fifths of the optic globe.Uveitis: Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)Blood-Aqueous Barrier: The selectively permeable barrier, in the EYE, formed by the nonpigmented layer of the EPITHELIUM of the CILIARY BODY, and the ENDOTHELIUM of the BLOOD VESSELS of the IRIS. TIGHT JUNCTIONS joining adjacent cells keep the barrier between cells continuous.Uveitis, Anterior: Inflammation of the anterior uvea comprising the iris, angle structures, and the ciliary body. Manifestations of this disorder include ciliary injection, exudation into the anterior chamber, iris changes, and adhesions between the iris and lens (posterior synechiae). Intraocular pressure may be increased or reduced.Anterior Eye Segment: The front third of the eyeball that includes the structures between the front surface of the cornea and the front of the VITREOUS BODY.Eye ProteinsAdministration, Topical: The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Timolol: A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.Sclera: The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)Exfoliation Syndrome: The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)Uvea: The pigmented vascular coat of the eyeball, consisting of the CHOROID; CILIARY BODY; and IRIS, which are continuous with each other. (Cline et al., Dictionary of Visual Science, 4th ed)Eye: The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.Toxoplasmosis, Ocular: Infection caused by the protozoan parasite TOXOPLASMA in which there is extensive connective tissue proliferation, the retina surrounding the lesions remains normal, and the ocular media remain clear. Chorioretinitis may be associated with all forms of toxoplasmosis, but is usually a late sequel of congenital toxoplasmosis. The severe ocular lesions in infants may lead to blindness.Glaucoma, Open-Angle: Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris.Cornea: The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)Ophthalmic Solutions: Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.Tonometry, Ocular: Measurement of ocular tension (INTRAOCULAR PRESSURE) with a tonometer. (Cline, et al., Dictionary of Visual Science, 4th ed)Iridocyclitis: Acute or chronic inflammation of the iris and ciliary body characterized by exudates into the anterior chamber, discoloration of the iris, and constricted, sluggish pupil. Symptoms include radiating pain, photophobia, lacrimation, and interference with vision.Cataract Extraction: The removal of a cataractous CRYSTALLINE LENS from the eye.Pupil: The aperture in the iris through which light passes.Transforming Growth Factor beta2: A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.Lens, Crystalline: A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.Endothelium, Corneal: Single layer of large flattened cells covering the surface of the cornea.Glaucoma, Neovascular: A form of secondary glaucoma which develops as a consequence of another ocular disease and is attributed to the forming of new vessels in the angle of the anterior chamber.Eye Infections: Infection, moderate to severe, caused by bacteria, fungi, or viruses, which occurs either on the external surface of the eye or intraocularly with probable inflammation, visual impairment, or blindness.Eye Diseases: Diseases affecting the eye.Tropicamide: One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.Carbonic Anhydrase Inhibitors: A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule through inhibition of CARBONIC ANHYDRASES.Prostaglandins F, Synthetic: Analogs or derivatives of prostaglandins F that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal PGF.Levobunolol: The L-Isomer of bunolol.Fluorescein: A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium such as the aqueous humor.HumorOcular Hypotension: Abnormally low intraocular pressure often related to chronic inflammation (uveitis).Macaca fascicularis: A species of the genus MACACA which typically lives near the coast in tidal creeks and mangrove swamps primarily on the islands of the Malay peninsula.Methazolamide: A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.Endophthalmitis: Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection.Laughter: An involuntary expression of merriment and pleasure; it includes the patterned motor responses as well as the inarticulate vocalization.Trabeculectomy: Any surgical procedure for treatment of glaucoma by means of puncture or reshaping of the trabecular meshwork. It includes goniotomy, trabeculectomy, and laser perforation.Eye Neoplasms: Tumors or cancer of the EYE.Injections: Introduction of substances into the body using a needle and syringe.Moxisylyte: An alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)Heptanol: A colorless liquid with a fragrant odor. It is used as an intermediate, solvent and in cosmetics.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Eye Infections, Viral: Infections of the eye caused by minute intracellular agents. These infections may lead to severe inflammation in various parts of the eye - conjunctiva, iris, eyelids, etc. Several viruses have been identified as the causative agents. Among these are Herpesvirus, Adenovirus, Poxvirus, and Myxovirus.Ocular Hypertension: A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.Retinal Necrosis Syndrome, Acute: Mild to fulminant necrotizing vaso-occlusive retinitis associated with a high incidence of retinal detachment and poor vision outcome.Venous Pressure: The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.Hydrophthalmos: Congenital open-angle glaucoma that results from dysgenesis of the angle structures accompanied by increased intraocular pressure and enlargement of the eye. Treatment is both medical and surgical.Ganglionectomy: Removal of an autonomic or sensory ganglion by any means.Corneal Transplantation: Partial or total replacement of the CORNEA from one human or animal to another.Miotics: Agents causing contraction of the pupil of the eye. Some sources use the term miotics only for the parasympathomimetics but any drug used to induce miosis is included here.

Estimation of corneal endothelial pump function in long-term contact lens wearers. (1/1321)

PURPOSE: To study the effects of long-term contact lens wear on morphologic and physiologic properties of corneal endothelial cells. METHODS: The endothelial permeability to fluorescein and the rate of corneal deswelling from hypoxia-induced edema were measured in 20 long-term (mean, 17+/-9 years; range, 5-33 years) contact lens wearers and 20 age-matched control subjects. From these data, the relative endothelial pump rate in each subject was estimated, based on the pump-leak hypothesis of corneal hydration control. Corneal autofluorescence and the aqueous humor flow rate were determined by fluorescein fluorophotometry. Images of corneal endothelial cells were recorded by using specular microscopy, and morphologic indices (cell density, coefficient of variation of cell area, percentage of hexagonal cells, and skewness) were determined. RESULTS: No statistically significant differences were found between the contact lens and control groups in endothelial permeability, corneal deswelling, relative endothelial pump rate ([mean +/- SD] 1.07+/-0.33 relative pump units versus 1.01+/-0.25 relative pump units; contact lens versus control; P = 0.57), and endothelial cell density. Contact lens wearers had a significantly higher aqueous humor flow rate (3.57+/-1.03 microl/min versus 2.77+/-0.51 microl/min; P = 0.005), coefficient of variation of cell area (0.35+/-0.09 versus 0.28+/-0.04; P = 0.006), and corneal autofluorescence (3.1+/-0.6 ng/ml versus 2.3+/-0.3 ng/ml fluorescein equivalents; P < 0.001) than did non-contact lens wearers. CONCLUSIONS: Despite the known effects of long-term contact lens wear on corneal endothelial morphometry, no effect on endothelial function was found.  (+info)

Latrunculin-A increases outflow facility in the monkey. (2/1321)

PURPOSE: To determine the effect of Latrunculin (LAT)-A, a macrolide that binds to G-actin, which leads to the disassembly of actin filaments, on shape, junctions, and the cytoskeleton of cultured bovine aortic endothelial cells (BAECs) and on outflow facility in living monkeys. METHODS: Latrunculin-A dose-time-response relationships in BAECs were determined by immunofluorescence and phase contrast light microscopy, facility by two-level constant pressure anterior chamber perfusion. RESULTS: In BAECs, LAT-A caused dose- and incubation time- dependent destruction of actin bundles, cell separation, and cell loss. Cell-cell adhesions were more sensitive than focal contacts. Recovery was also dose- and time-dependent. In monkeys, exchange intracameral infusion and topical application of LAT-A induced dose- and time-dependent several-fold facility increases. The facility increase was completely reversed within several hours after drug removal. However, for at least 24 hours after a single topical LAT-A dose, perfusion with drug-free solution caused an accelerated increase in facility beyond that attributed to normal resistance washout. CONCLUSIONS: Pharmacological disorganization of the actin cytoskeleton in the trabecular meshwork by specific actin inhibitors like LAT-A may be a useful antiglaucoma strategy.  (+info)

Effect of staurosporine on outflow facility in monkeys. (3/1321)

PURPOSE: To determine the effect of the serine-threonine kinase inhibitor staurosporine on outflow facility in living monkeys. METHODS: Total outflow facility was determined by two-level constant pressure perfusion of the anterior chamber bilaterally before and after intracameral infusion of staurosporine or vehicle in opposite eyes. RESULTS: Intracameral staurosporine dose-dependently doubled outflow facility, with 0.1 microM, 1 microM, and 10 microM being subthreshold, effective, and maximal doses, respectively. At 50 microM, intracameral staurosporine was less effective than 10 microM on facility and induced corneal toxicity. CONCLUSIONS: The broad-spectrum protein kinase inhibitor staurosporine increases outflow facility in living monkeys, perhaps by affecting the trabecular meshwork cytoskeleton.  (+info)

Cytomegalovirus (CMV) retinitis activity is accurately reflected by the presence and level of CMV DNA in aqueous humor and vitreous. (4/1321)

To evaluate the potential of ocular and systemic specimens to provide markers of active cytomegalovirus (CMV) retinitis, we examined the relationship between virologic and clinical aspects of CMV infections in AIDS patients with CMV retinitis. CMV polymerase chain reaction (PCR) analysis of 74 aqueous humor and vitreous specimens indicated that ocular specimens can provide accurate markers to differentiate active and inactive CMV retinitis (aqueous or vitreous PCR, P<.001). Moreover, these markers were superior to extraocular measures, including plasma PCR (P=.08) and blood and urine CMV cultures (P=.05). A direct correlation was identified between the quantity of CMV DNA in aqueous humor or vitreous specimens and the corresponding surface area of active CMV retinitis (r2=.69 and.44, respectively). Thus, qualitative and quantitative PCR-based analyses of aqueous humor can provide valuable markers of CMV retinitis activity. Such assays could provide rapid and reliable tools to assist in management of patients with CMV retinitis in whom the view of the retina is obscured.  (+info)

High frequency of persistent hyperplastic primary vitreous and cataracts in p53-deficient mice. (5/1321)

In order to investigate whether the p53 gene product plays a role in normal eye development, age matched p53-deficient mice and wild-type controls were sacrificed from day 2 to day 21 after birth. Eyes were paraffin-embedded and sectioned. Serial sections were taken at the level of the tunica vasculosa lentis and the hyaloid artery. The terminal dUTP nick-end labelling technique (TUNEL) was used to detect the number of cells displaying DNA fragmentation within these structures. Eyes were also prepared for scanning electron microscopy and resin embedded for semi-thin sections. Adult wild-type mice and p53-deficient mice were examined ophthalmoscopically in vivo. Ophthalmoscopical examination of mice completely deficient in p53 revealed them to be normal except for the persistence of the hyaloid vasculature, a structure that normally regresses during eye development. In adult animals there was also a high frequency of cataracts. Using morphological assessment and TUNEL we could show that in normal mice, regression of the primary vitreous, which includes the hyaloid artery, the vasa hyaloidea propria as well as the tunica vasculosa lentis, occurs via apoptotic cell death within 5 - 6 weeks after birth. The number of TUNEL-positive cells within these structures was significantly reduced in the p53-deficient mice in which parts of the hyaloid vasculature persisted and developed into a fibro-vascular retrolental plaque analogous to persistent hyperplastic primary vitreous (PHPV) described in humans. As in humans, PHPV in mice resulted in the development of cataracts. We have identified a role for p53-dependent apoptosis in the regression of the hyaloid vasculature and tunica vasculosa lentis. Our results provide further evidence for the importance of p53 in normal development and provide the first detailed evidence of its role in postnatal development in remodelling the developing eye.  (+info)

Electrical parameters of the isolated cornea of the dogfish, Squalus acanthias. (6/1321)

The electrical potential difference and electrical resistance of the nonswelling cornea of the dogfish, Squalus acanthias, were examined. It was found that routine procedures used in the procurement of fish invariably produce damage to the corneal epithelium which affects electrical measurements and possibly composition of the aqueous humor. We found no electrical evidence of ionic pumps in the corneal epithelium of this elasmobranch. The electrical resistance of corneas with apparently well-preserved epithelium was 300omega-cm.2 (compared to 30omega-cm.2 in corneas with damaged epithelium).  (+info)

Enthacrynic and acid effects on inner wall pores in living monkeys. (7/1321)

PURPOSE: The influence of the inner wall of Schlemm's canal on aqueous outflow facility remains poorly understood. We examined the relationship between inner wall pore characteristics and outflow facility in living primate eyes in which facility had been pharmacologically increased by ethacrynic acid (ECA) infusion and in contralateral control eyes. METHODS: Outflow facility (two-level constant pressure perfusion) was measured in eight pairs of living monkey eyes before and after administration of a bolus dose of either 0.125 mM ECA or vehicle. After exsanguination, eyes were fixed in situ under constant-pressure conditions (mean fixation pressure approximately 19 mm Hg). The density and diameter of inner wall pores and the number and area of platelet aggregates on the inner wall of Schlemm's canal were measured by scanning electron microscopy. RESULTS: In ECA-treated eyes, outflow facility increased 63% (P < 0.0001), intracellular pore density decreased 46% (P = 0.0094), intracellular pore size increased 27% (P = 0.049), platelet aggregate density increased 158% (P < 0.0001), and area covered by platelets increased 210% (P = 0.012) relative to contralateral controls. Although the average density and size of intercellular pores were essentially unaffected by ECA, an increased density of large (> or = 1.90 microm) intercellular pores was seen in ECA-treated eyes. The density of intracellular pores increased with the duration of fixative perfusion. Other than a weak negative correlation between outflow facility and intracellular pore density in ECA-treated eyes (P = 0.052), facility was not correlated with inner wall pore features. CONCLUSIONS: Our data are most consistent with a scenario in which ECA promotes formation of large intercellular pores in the inner wall of Schlemm's canal, which are then masked by platelet aggregates. Masking of intercellular pores, combined with fixation-induced alteration of inner wall pore density, greatly complicates attempts to relate facility to inner wall structure and suggests that in vivo pore density is smaller than in fixed tissue. Additionally, facility-influencing effects of ECA on the juxtacanalicular tissue cannot be excluded.  (+info)

Effect of aqueous humor on apoptosis of inflammatory cell types. (8/1321)

PURPOSE: To determine whether aqueous humor promotes cell death in cells involved in inflammatory responses. METHODS: Multiple immune cell types, most characteristically involved in inflammatory responses, were incubated for 24, 48, and 72 hours in the presence or absence of 50% aqueous humor. Promotion of cell death was assayed by staining for an early indicator of apoptosis. The percentage of cells undergoing apoptosis was measured by flow cytometry. To identify partially the apoptosis inducing factor, aqueous humor was pretreated with proteinase K to degrade protein. In other experiments, aqueous humor was fractionated by centrifugation on filters capable of separating molecules above and below 10 kDa or 30 kDa kilodaltons in size. RESULTS: Rabbit aqueous humor promoted apoptosis in a wide variety of immune cells, including lymphokine-activated natural killer cells, resting T cells, an activated T-cell line, RAW 264.7 and J774A0.1 monocyte-macrophage cell lines, and neutrophils. As previously shown, aqueous humor did not promote apoptosis of murine corneal endothelial cells. Apoptosis was also not induced in human corneal endothelium, mouse corneal epithelium, or iris/ciliary body cell lines. Instead, aqueous humor partially protected these ocular tissues from starvation-induced cell death. Pretreatment with proteinase K inhibited the apoptosis-inducing activity. Moreover, the apoptosis-inducing activity segregated with the aqueous humor fraction containing molecules less than than 10 kDa in size. CONCLUSIONS: These data show that aqueous humor contains a factor or factors that promote death of cells that participate in inflammatory processes. By contrast, ocular tissues, such as the corneal endothelium and iris/ciliary body, are impervious to aqueous humor-induced cell death. The aqueous humor- borne factor(s) may contribute to the immune privilege of the anterior chamber by purging potential inflammatory cells.  (+info)

*Fitxer:Schematic diagram of human eye multilingual.svg - Viquipèdia, l'enciclopèdia lliure

Add arteries and veins, aqueous humor, corneosclera. Resize tendons. Redraw ora serrata. ... Vitreous humor with 19. Hyaloid canal/(old artery), 20. Retina with 21. Macula or macula lutea, 22. Fovea and 23 Optic disc → ... 1. Lens, 2. Zonule of Zinn or Ciliary zonule, 3. Posterior chamber and 4. Anterior chamber with 5. Aqueous humour flow; 6. ...

*Biophotonics

... aqueous humor, or sputum. Stimulating light excites an electron, raising energy to an unstable level. This instability is ...

*Schlemm's canal

... is a circular lymphatic-like vessel in the eye that collects aqueous humor from the anterior chamber and ... On the inside of the canal, nearest to the aqueous humor, it is covered by the trabecular meshwork; this region makes the ... greatest contribution to outflow resistance of the aqueous humor. Conventionally, the canal has been considered a blood vessel ... delivers it into the episcleral blood vessels via aqueous veins.[1][2][3][4] It is named after Friedrich Schlemm (1795-1858), a ...

*Rapid eye movement sleep

... enables the aqueous humor to circulate. When the animal is sleeping, REM provides the much-needed stir to aqueous humor. This ... he calculated that if aqueous humor was stagnant, oxygen from iris had to reach cornea by diffusion through aqueous humor, ... and that aqueous humor, the liquid between cornea and iris, was stagnant if not stirred.[105] Among the supportive evidences, ...

*Intraocular pressure

... is mainly determined by the coupling of the production of aqueous humor and the drainage of aqueous humor ... Brubaker RF (1991). "Flow of aqueous humor in humans". Invest Ophthalmol Vis Sci. 32 (13): 3145-3166. PMID 1748546. Hashemi, H ... F the rate of aqueous humour formation in microliters per minute (μL/min) U the resorption of aqueous humour through the ... During the night, intraocular pressure may not decrease despite the slower production of aqueous humour. In the general ...

*Corneal ulcers in animals

The endothelium is a single cell layer that separates the cornea from the aqueous humor. ... There may also be signs of anterior uveitis, such as miosis (small pupil), aqueous flare (protein in the aqueous humour), and ...

*Vitreous body

The vitreous does not undergo a regular formation and drainage process like the aqueous humor. Instead, it stays permanently in ... aqueous humour) which is continuously replenished, the gel in the vitreous chamber is stagnant. Therefore, if blood, cells or ... "Encyclopædia Britannica from Encyclopædia Britannica 2006 Ultimate Reference Suite DVD 2009 The Vitreous Humor Archived April ...

*5α-Reductase inhibitor

5α-Dihydrocortisol is present in the aqueous humor of the eye, is synthesized in the lens, and might help make the aqueous ... "5 alpha-dihydrocortisol in human aqueous humor and metabolism of cortisol by human lenses in vitro". Invest. Ophthalmol. Vis. ... humor itself.[34] 5α-Dihydroaldosterone is a potent antinatriuretic agent, although different from aldosterone. Its formation ...

*Vitreous chamber

Vitreous humor Vitreous detachment Aqueous humor "Eye (Vertebrate)". Gale Virtual Reference Library. McGraw-Hill Professional. ... This chamber is filled with a thick, clear gel-like substance called the vitreous humor (also vitreous body). The humor plays a ... The vitreous chamber is the space in the eye occupied by vitreous humor. Within the vertebrate eye, there are considered to be ...

*Minimally invasive glaucoma surgery

... a part of the uveoscleral outflow pathway for aqueous humor. The uveoscleral pathway is an important pathway for aqueous ... Aqueous humor is produced in the portion of the eye known as the ciliary body. The ciliary body contains 72 protrusions known ... The trabecular outflow is one of the major outflow pathways for aqueous humor in the eye and has been the target of both ... Toris, CB (2008). "Chapter 8: Aqueous Humor Dynamics II - Clinical Studies". Current Topics in Membranes. Heine L. Die ...

*Prostaglandin analogue

Winkler, NS; Fautsch, MP (2014). "Effects of prostaglandin analogues on aqueous humor outflow pathways". Journal of Ocular ... and subsequent studies found that this was due to increasing the outflow of aqueous humor, mainly by relaxing the ciliary ...

*Rajko Igić

Metabolism of angiotensin I by guinea pig aqueous humor. Can J Physiol Pharmacol 2001;79:627-30. Igić R, Behnia R. Properties ...

*Glaucoma valve

Eye surgery Glaucoma surgery Brubaker, Richard F. (1991-12-01). "Flow of Aqueous Humor in Humans [The Friedenwald Lecture]". ... are transscleral implants to channel aqueous humor into the non-dissected Tenon's space, creating a subconjunctival drainage ... due to the ongoing scarring over the conjunctival dissipation segment of the shunt may become too thick for the aqueous humor ... A Cochrane Review of various aqueous shunts and modifications found that the Baerveldt implant may result in lower IOP than the ...

*Μ-opioid receptor

Dortch-Carnes J, Russell K (2007). "Morphine-stimulated nitric oxide release in rabbit aqueous humor". Exp. Eye Res. 84 (1): ...

*Apraclonidine

"Effects of Apraclonidine on Aqueous Humor Dynamics in Human Eyes". Ophthalmology. 102 (3): 456. doi:10.1016/S0161-6420(95)31000 ...

*Glaucoma surgery

Scar formation at the site of excision or operation may block aqueous humor circulation, while healthy tissue regeneration will ... Certain cells within the eye's ciliary body produce aqueous humor. A ciliary destructive or cyclodestructive procedure is one ... that facilitate the escape of excess aqueous humor from the eye to lower intraocular pressure, and a few that lower IOP by ... A surgical goniotomy involves cutting the fibers of the trabecular meshwork to allow aqueous fluid to flow more freely from the ...

*Brimonidine/timolol

Larsson, LI (2001). "Aqueous humor flow in normal human eyes treated with brimonidine and timolol, alone and in combination". ... Both substances work by decreasing the synthesis of aqueous humor. Combigan is marketed and sold by Allergan. It has been ... Brimonidine exerts its ocular hypotensive effect by decreasing aqueous humor production and increasing uveoscleral outflow, ... while timolol acts by reducing aqueous humor production. Combigan has a fast onset of action, and the peak IOP lowering effect ...

*Brimonidine

It acts via decreasing synthesis of aqueous humor, and increasing the amount that drains from the eye through uveoscleral ... Toris, C.; Camras, C.; Yablonski, M. (1999). "Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular ... This vasoconstriction may explain the acute reduction in aqueous humor flow. The increased uveoscleral outflow from prolonged ... This reduces cAMP and hence aqueous humour production by the ciliary body. Peripheral α2 agonist activity results in ...

*Florian Verrey

Clinic on aqueous humor pathology. L'humeur aqueuse et ses fonctions, (with Marc Amsler and Alfred Huber, 1955) - Aqueous humor ... He was the author of 74 medical papers, many of which concerned the eye's aqueous humor. He was also interested in uveitis; in ...

*Anterior chamber of eyeball

Aqueous humor is the clear fluid that fills the anterior chamber. Hyphema, anterior uveitis and glaucoma are three main ... In glaucoma, blockage of the trabecular meshwork prevents the normal outflow of aqueous humour, resulting in increased ...

*Ocular ischemic syndrome

Additional measures include paracentesis of aqueous humor to decrease IOP acutely. An ESR should be drawn to detect possible ...

*Corneal perforation

If the clear aqueous humor from the eye runs through the yellow stain, the patient tests positive for corneal perforation. ... Any aqueous leakage is revealed during the Seidel test confirms corneal perforation. A fluorescence strip is wiped over the ...

*Mi opioidni receptor

"Morphine-stimulated nitric oxide release in rabbit aqueous humor". Exp. Eye Res. 84 (1): 185-90. PMC 1766947. PMID 17094965. ...

*Ibopamine

So ibopamine can not be found in the aqueous humor after instillation. After being hydrolysed to epinine, ibopamine is able to ... It has been shown that the half-life of ibopamine is short to about 2 minutes in the aqueous humour owing to the fast ... Due to the esterases existed in the aqueous humour and ocular tissues, ibopamine can be rapidly hydrolysed to epinine which is ... In some randomized clinical trials, the D1 dopaminergic activity of ibopamine led to an increased production of aqueous humour ...

*Ciliary body

... and these secrete aqueous humor into the posterior chamber. The aqueous humor then flows through the pupil into the anterior ... Eighty percent of aqueous humor production is carried out through active secretion mechanisms (the Na+K+ATPase enzyme creating ... Because the ciliary body produces aqueous humor, it is the main target of many medications against glaucoma. Its inhibition ... The ciliary body has three functions: accommodation, aqueous humor production and resorption, and maintenance of the lens ...

*Trabeculectomy

It is the most common glaucoma surgery performed and allows drainage of aqueous humor from within the eye to underneath the ... Intraocular pressure may be lowered by allowing drainage of aqueous humor from within the eye to the following routes: (1) ... Various adjunctive devices have been used with trabeculectomy, to maintain drainage of aqueous humor and to maintain the ... Glaucoma medications are usually discontinued to improve aqueous humor flow to the bleb. Topical medications consist typically ...

*Ocular hypertension

Medications that lower intraocular pressure work by decreasing aqueous humor production and/or increasing aqueous humor outflow ...

*Glaucoma

... whose original function is to absorb the aqueous humor. Loss of aqueous humor absorption leads to increased resistance and thus ... Aqueous humor flows from the ciliary processes into the posterior chamber, bounded posteriorly by the lens and the zonules of ... This accumulation of aqueous humor causes an acute increase in pressure and pain. The inconsistent relationship of glaucomatous ... The mechanism of open-angle glaucoma is believed to be slow exit of aqueous humor through the trabecular meshwork while in ...
Purine nucleotide degradation products have been determined by HPLC in aqueous humor obtained during cataract surgery and from plasma of 22 patients (12 women). Uric acid, cytosine, guanosine monophosphate, uracyl, guanine, adenosine, adenosine monophosphate, thymine, adenine, inosine, cyclic guanosine monophosphate, hypoxanthine and xanthine were evaluated. Uric acid and the last two were the only compounds detectable in measurable amounts in aqueous humor and in plasma of all patients. Aqueous humor xanthine levels were not significantly different from plasma; aqueous humor hypoxanthine concentrations were lower than those of xanthine and than plasma oxypurine levels. In 8 patients, treated with allopurinol, oxypurinol concentrations in aqueous humor and in plasma were comparable suggesting that oxypurines are transported through the blood-aqueous humor barrier.. ...
Synonyms for aqueous humor in Free Thesaurus. Antonyms for aqueous humor. 1 synonym for aqueous humor: aqueous humour. What are synonyms for aqueous humor?
Purpose: : Recent studies in our laboratory have demonstrated that nitric oxide plays a role in morphine-induced reduction of intraocular pressure and pupil diameter in New Zealand white (NZW) rabbits. The goal of the present study was to determine the effect of morphine on nitric oxide levels in the aqueous humor of NZW rabbits. Methods: : Normal, dark-adapted (reverse light cycle, 12/12 hr dark/light) NZW rabbit eyes were treated topically and bilaterally as follows: 1) morphine (100 µg) for 5 or 30 minutes; 2) 30 minute pretreatment with naloxone (100 µg; a nonselective opioid receptor antagonist) or L-NAME (0.5 %; a nitric oxide synthase inhibitor), followed by treatment with morphine for 5 or 30 minutes. Aqueous humor samples were obtained by paracenthesis and immediately assayed for nitric oxide (nitrites + nitrates) using a nitric oxide quantitation kit. Results: : The levels of NO in aqueous humor of rabbits treated with morphine for 5 minutes, increased from 34.22 ± 2.22 µM ...
Although the resistance to outflow, postoperatively, is probably dependent on the TDM,7 proponents of viscocanalostomy4 advocate tightly suturing the superficial flap in an attempt to avoid subconjunctival filtration. Whether tightly or loosely suturing the flap affects the overall outflow facility changes after NPGS has, to our knowledge, not been investigated before.. We report an in vitro mean preoperative outflow facility in isolated porcine eyes, in line with previously published work.11 The mean (SD) outflow facility after NPGS (1.584 (0.217) μl/min/mm Hg) is relatively lower than previously reported mean outflow facility after trabeculectomy11 (2.957 (0.602) μl/min/mm Hg), which possibly accounts for the gradual decrease in IOP after NPGS, as opposed to the sudden drop in pressure after penetration as in the case of trabeculectomy.. According to McEwen12 a single patent hole of 12 μm is by itself sufficiently large to provide a normal facility of outflow. Based on this we would have ...
Purpose: To look at the influence of aqueous humour protein content and viscosity, which may increase in anterior chamber inflammation, on equilibrium pressure under the scleral flap in trabeculectomies. The influence of suture numbers and scleral flap shapes was also investigated. Methods: Normal and uveitic aqueous humour were represented by plain BSS, BSS containing 300 mg/ 100 ml of albumin and BSS containing 3000 mg/ 100 ml of albumin. Porcine corneoscleral rims were mounted on a Barron artificial anterior chamber and chamber pressure was measured using a pressure transducer. 4 mm x 4 mm partial thickness scleral flaps and 0.75 mm diameter sclerostomies were created, followed by re-suturing of the flap with either 2 or 4 sutures, as in a trabeculectomy. Equilibrium pressure in the chamber was noted. The square scleral flaps were also compared with 4 mm x 3 mm rectangular and 4 mm x 4 mm triangular flaps. In all cases, n = 8. Statistical analysis involved the unpaired t-test and one-way ...
GALLARDO, C.; PAREDES, E. e PEREZ, J.. Histopathological study of canine liver and kidney and their relationship with blood and postmortem aqueous humour samples concentrations of urea, creatinine, proteins and enzymes activities (ALT and SAP). Arch. med. vet. [online]. 2003, vol.35, n.1, pp.61-74. ISSN 0301-732X. http://dx.doi.org/10.4067/S0301-732X2003000100006.. The goal of this study was to characterize histopathological lesions of the liver and kidney of canines, and their relationship with blood and postmortem samples of aqueous humor concentrations of urea, creatinine, proteins and ALT and SAP plasmatic activity. Thirty one animals were used in this study. They did not have clinical history of hepatic or renal diseases. Plasma samples were obtained before euthanasia. A sample of aqueous humor was obtained from the right eye of each dog just after euthanasia and a similar sample was obtained 24 hours later from the left eye. Urea, creatinine and protein concentrations and plasmatic ...
Experimental Eye Research, Vol: 127, Pages: 224-235, ISSN: 1096-0007 The bulk of aqueous humor passing through the conventional outflow pathway must cross the inner wall endothelium of Schlemms canal (SC), likely through micron-sized transendothelial pores. SC pore density is reduced in glaucoma, possibly contributing to obstructed aqueous humor outflow and elevated intraocular pressure (IOP). Little is known about the mechanisms of pore formation; however, pores are often observed near dome-like cellular outpouchings known as giant vacuoles (GVs) where significant biomechanical strain acts on SC cells. We hypothesize that biomechanical strain triggers pore formation in SC cells. To test this hypothesis, primary human SC cells were isolated from three non-glaucomatous donors (aged 34, 44 and 68), and seeded on collagen-coated elastic membranes held within a membrane stretching device. Membranes were then exposed to 0%, 10% or 20% equibiaxial strain, and the cells were aldehyde-fixed 5 min after ...
A pioneering dye-based technique that enables aqueous humour outflow to be studied has the potential to improve glaucoma angle-based procedures and surgery outcomes.
Glaucoma is a leading cause of blindness, with an estimated world-wide prevalence of 3.5% in members of the population older than 40 years of age. Elevated intraocular pressure as the result of abnormal resistance to aqueous humor drainage is a major contributing, and the only preventable, factor in glaucoma development. Schlemms canal (SC), a lymphatic-like vessel encircling the anterior portion of the eye, plays a key role in promoting aqueous humor outflow and maintenance of normal intraocular pressure. The risk of developing glaucoma increases with age; therefore, understanding mechanisms of SC maintenance and how aging affects SC function are of special importance, both for prevention and novel treatment approaches to glaucoma. Using a compelling array of genetic models, Kim et al. report in this issue of the JCI that continuous angiopoietin/TIE2 signaling is required for maintaining SC identity and integrity during adulthood and show that its age-related changes can be rescued by a TIE2 ...
Expression levels of 87 proteins were found to be different between glaucomatous and control aqueous humor. Of the 87 proteins, 34 were significantly upregulated, whereas 53 proteins were downregulated in the aqueous humor from glaucoma patients compared to controls. Differentially expressed proteins were found to be involved in cholesterol-related, inflammatory, metabolic, antioxidant as well as proteolysis-related processes.. CONCLUSION ...
In the anterior part of our eye there are two cavities filled with a watery but nutritive fluid called aqueous humor. One cavity, called the anterior chamber, lies just behind the cornea and in front of the iris. The other, called the posterior chamber, is a narrow space behind the iris and is surrounded by a mucsuloepithelial structure called the ciliary body. Aqueous humor is contiuously formed into the posterior chamber by the double layer ciliary epithelium that covers the ciliary body. Aqueous humor then sips through the hole at the center of iris, called the pupil, into the anterior chamber. Excess aqueous humor leaves the anterior chamber, by a pressure dependent way, mainly through a sieve-like structure called the trabecular meshwork located at the junction of the cornea and the sclera. Apart from supplying the nutrients and removing metabolic wastes from the avascular tissues of the eye, namely, the cornea, trabecular meshwork and the lens, the aqueous humor maintains the optimum ...
accommodation: ability of the lens to adjust its shape for vision at various distances in order to produce a clear image on the retina.. anterior chamber: space in front portion of the eye between the cornea and the iris and lens, which is filled with aqueous humor. aqueous humor: clear, watery fluid that fills the anterior chamber and the posterior chamber in the front part of the eye and provides nutrients to structures in the anterior chamber.. aqueous outflow pathway: the main exit route of aqueous humor from the eye, including the trabecular meshwork and Schlemms canal.. astigmatism: irregular curvature of the cornea or lens resulting in a distorted image because light rays are not focused on a single point on the retina.. binocular vision: coordinated use of the two eyes to see a single fused three-dimensional image.. blindspot: in testing the visual field, this is the blind area corresponding to the optic disk where the optic nerve fibers exit the eye and where there are no ...
Primary open-angle glaucoma (POAG) is often caused by elevated intraocular pressure (IOP), which arises due to increased resistance to aqueous humor outflow (AHO). Aqueous humor flows through Schlemms canal (SC), a lymphatic-like vessel encircling the cornea, and via intercellular spaces of ciliary muscle cells. However, the mechanisms underlying increased AHO resistance are poorly understood. Here, we demonstrate that signaling between angiopoietin (Angpt) and the Angpt receptor Tie2, which is critical for SC formation, is also indispensable for maintaining SC integrity during adulthood. Deletion of Angpt1/Angpt2 or Tie2 in adult mice severely impaired SC integrity and transcytosis, leading to elevated IOP, retinal neuron damage, and impairment of retinal ganglion cell function, all hallmarks of POAG in humans. We found that SC integrity is maintained by interconnected and coordinated functions of Angpt-Tie2 signaling, AHO, and Prox1 activity. These functions diminish in the SC during aging, ...
Relationship between the severity of macular edema and the aqueous humour concentrations of cytokines.A. IL-1β. B. IL-6. C. IL-8. D. IP-10. E. MCP-1. F. VEGF.
J Room Physiol 143:439В444 de Carvalho EF, de Castro FT, Rondinelli E, Carvalho JF (1994) Physiological aspects of Trypanosoma cruzi gene control during heat-shock. P2X4 receptors induced in spinal microglia barrier tactile allodynia after tenacity injury. 1 pct of men and 21 buy 5 mg proscar with visa prostate cancer questions. In its original 2 years, the GOG was in discus- sions with the Childrens Oncology Set (RATCHET) to col- laborate on a usage for the benefit of scrutiny inasmuch as low-risk disease and compressed BEP repayment for intermediate-risk disease. They like using toys in behalf of their intended tenacity as beyond the shadow of a doubt as for whatever invented ambition they can imagine. You pot motley this likewise cheap super cialis 80 mg free shipping erectile dysfunction medication australia. Peak aqueous humor concentrations of triamcinolone ranged from 2,151 to 7,202 ng/mL, half-life 76В635 h, and AUC0Вt 231 to 1,911 ng h/mL following celibate intravitreal ...
The most critical risk factor for optic nerve damage in cases of primary open-angle glaucoma (POAG)(31) is an increased intraocular pressure (IOP) due to alternation of tissues in the eye located around the base of the cornea(32). Actin, a critical player in many cellular functions, including cell motility and the maintenance of cell shape, etc.(33), disruption or taken over actin cytoskeleton by numerous pathogens(34), may induce a resistance to aqueous humor outflow in the trabecular meshwork (TM)(36), an area of tissue is responsible for draining the aqueous humor from the eye via the anterior chamber causes of optic nerve damage involved connective tissue growth factor (CTGF), found in higher amounts in the aqueous humor of patients with POAG(35 ...
Its not just what we say that matters, but how we say it when it comes to building a great, safe culture, said Kerr. Humour makes people more approachable; it helps build connections and relationships and break down walls. Humour not only helps messages stand out, relevant humour reduces the "counter-argument part of the brain" - that part of peoples brains where they immediately start building arguments about why they are not going to do something - so people are more accepting of a message, said Kerr.. "If you deliver a message, a rule, a regulation, a safety policy with a little bit of humour, studies show people are five times more likely to go along with you if you do it in a funny way," he said.. Some ways to do this are by using a top 10 list, opening with a funny story, using humour in safety videos - just doing something to add a little bit of humour into the mix.. "We need to make sure we are coming up with creative opportunities to share our messages in more fun ways so we are truly ...
Disclaimer: This is a medical humor and parody website meant solely for entertainment purposes, and is not intended to recommend or advise regarding the prevention, diagnosis, or treatment of any medical illness or condition. Stories and articles are meant only to provide a brief, fleeting distraction from the wretchedness of reality, and are not intended to be insensitive, callous, or offensive, or to otherwise belittle the plight of those affected with any medical disease, condition, or illness. All names and descriptions of people are fictitious except for those of well-known public figures, who are the subject of satire. Any resemblance to actual persons or events is purely coincidental. Medical Humor is just that: Medical Humor.. ...
Objectives Improve understanding of positive and negative humor. Increase knowledge of how humor affects our physical, psychological and social wellbeing. Focus on the use of humor for persons with Short Term Memory Loss, and their caregivers. Set out techniques to improve utilization of humor and exposure to humor in daily life. Laugh and tell a few illustrative jokes.
The Short Humour (Humor) Site aims to promote the reading and writing of Short Humour (Humor) both in Britain and throughout the world and also to showcase work by writers of the genre.
Synonyms for cardinal humours in Free Thesaurus. Antonyms for cardinal humours. 54 synonyms for humour: comedy, funniness, fun, amusement, funny side, jocularity, facetiousness, ludicrousness, drollery, comical aspect, mood, spirits, temper. What are synonyms for cardinal humours?
Methods of treating ocular disorders are disclosed, such as a method that includes inserting an implant in eye tissue, using a delivery instrument, such that an inlet portion of the implant is in an anterior chamber of an eye and an outlet portion of the implant is in a physiological outflow pathway; removing the delivery instrument from the eye without removing the implant; and conducting fluid comprising a therapeutic substance through the implant and into the physiological outflow pathway. Another method includes inserting an instrument into a physiologic outflow pathway through which aqueous humor drains from an anterior chamber of an eye; separating first and second walls of tissues which comprise the physiologic outflow pathway by injecting a fluid comprising a drug from the instrument while the instrument remains in the physiologic outflow pathway; and withdrawing the instrument following the injection with said fluid remaining within the eye such that the drug has a therapeutic effect on the eye
Shunt devices and a method for continuously decompressing elevated intraocular pressure in eyes affected by glaucoma by diverting excess aqueous humor from the anterior chamber of the eye into Schlemms canal where post-operative patency can be maintained with an indwelling shunt device which surgically connects the canal with the anterior chamber. The shunt devices provide uni- or bi-directional flow of aqueous humor into Schlemms canal.
The healthy eye is filled with a clear fluid called aqueous humor which circulates inside the front portion of your eye. Your eye continually produces a small amount of aqueous humor while an equal amount flows out of your eye in order to maintain a constant healthy eye pressure. Glaucoma means that the aqueous humor is not flowing out of your eye properly and that pressure in the eye is building up. This pressure can cause damage to your optic nerve over time.. Early detection is key with glaucoma. People of any age with glaucoma symptoms or glaucoma risk factors, such as diabetes, family history of glaucoma, or those of African descent, should see an ophthalmologist regularly.. ...
Thank you for visiting us at the Childrens Humor Study!. We would like to invite you and your child to consider participation in an exciting new research study to increase our understanding of the development of humor.. In this study we aim to examine the brain development and function, specifically as it relates to cognition and humor. We are currently seeking typically-developing children (ages 6-12) who are native English-speakers. For more information about our research findings related to humor in adults, please read our labs publications. If you are interested in learning more abour our current study, please read through this website.. Study Goals:. This study is directed by Drs. Allan Reiss (Stanford University) and Jessica Black (Boston College). The goals of the study are to:. ...
The aqueous humor is a clear fluid that maintains the integrity of the eye. It is produced by the ciliary body and passes through the trabecular meshwork and Schlemms canal. Intraocular pressure (IOP) is determined by the amount of aqueous humor secreted, coupled with the rate of clearance from the eye. An elevated IOP leads to optic nerve deterioration and associated irreversible functional vision loss.[1][2]
Anterior chamber. The space inside the eye between the corneal endothelium (innermost layer of the cornea) and the iris. This space is filled with fluid called the aqueous humor.. Aqueous (A-kwee-us), aqueous humor. Clear watery substance filling the space between the cornea and the vitreous. The fluid contains nutrients that nourishes certain structures of the eye. It also plays a role in maintaining the intra ocular pressure (IOP), and in the normal state maintains a fine balance between its production and its drainage.. Conjunctiva (kohn-junk-TI-vah). Transparent mucous membrane covering the outer surface of the eyeball. It is continuous with the inner part of the upper and lower eyelid (fornices).. Cornea (KOR-nee-ah). This is the transparent structure at the front of the globe. It provides a pathway for light to enter the front part of the eye in order to reach the retina, playing an integral part of the refractive power of the eye.. Crystalline lens. The eyes natural lens is usually a ...
Monocytes have been shown to normally circulate through the trabecular meshwork (TM) and to be recruited in increased numbers to the TM following the applicatio...
Clear liquid called aqueous humor circulates inside the front portion of the eye. To maintain a healthy level of pressure within the eye, a small amount of this fluid is produced constantly while an equal amount flows out of the eye through a microscopic drainage system. (This liquid is not part of the tears on the out surface of the eye.). Because the eye is a closed structure, if the drainage area for aqueous humor - called the drainage angle - is blocked, the excess fluid cannot flow out of the eye. Fluid pressure within the eye increases, pushing against the optic nerve and causing damage.. Who is at risk for glaucoma? ...
A device is made up of one piece, or two independent pieces, that can be linked with each other to make a unit. The anterior end of a drainage tube is introduced 2 mm into the anterior chamber of the eye while the rear end of the tube is placed in the scleral lake. A cover is a plane body slight in height and oval or oblong in format that is provided with four parallel cuts that create two girths. The said girths are used to retain the drainage tube below the cover, thus creating a curvature in it to form a concave inner surface and a convex outer surface.
A method and apparatus for measuring an apparent depth of a section of an animal body are disclosed. Light is focused concurrently to an extended focal region comprising a plurality or continuum of measurement locations. Light reflected by a refractive index interface coincident with one of the plurality of measurement locations is detected. Detected light signals are generated from light reflected from first and second interfaces respectively defining the section under investigation, so that the apparent positions of the interfaces may be derived. A confocal arrangement and an axicon element may be employed. Preferably, the section is the aqueous humor of an eye. From changes in its refractive index corresponding changes in glucose concentration in the aqueous humor and, in turn, in the bloodstream of a patient may be derived, offering a non-invasive monitoring means for diabetic patients. Other compounds and structures of the body may alternatively be investigated.
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Humor is laughing at what you havent got when you ought to have it. - Langston Hughes The latest brand or style of humor [as well as art] is fascinating in its blunt, in-your-face approach. Not just to the audience but to the travails of the zeitgeist, if such ludicrous terminology makes sense. And how…
This page includes the following topics and synonyms: Eye Anatomy, Limbus Corneae, Iris, Conjunctiva, Aqueous Humor, Aqueous Outflow Angle.
NMC Health has been in freefall since December 2019, when short-seller Muddy Waters Capital accused it of financial improprieties
BioreclamationIVT provides various types of matrices from human and animal species. The human samples are collected from consented donors at IRB approved facilities located in the United States. The animal samples are collected at facilities located in the United States. Both collections follow BioreclamationIVT Standard Operating Procedures. This allows us to customize every order according to your exact specifications, while maintaining the highest level of product quality. The list of matrices that is provided is not all inclusive. Our large network of sites provides us with limitless options when procuring other fluid type matrices. Amniotic Fluid Feces Sputum Aqueous Humor Gastric Fluid Synovial Fluid (lavage) Bile Hair Tears Bone Marrow Nasal Swabs Throat Swabs Breast Milk Nasal Swabs Urine Bronchial Lavage Saliva Vaginal Fluid Cerebrospinal Fluid Semen Vitreous Humor
The World Turned Upside Down: Revolutions in the Microcosm and Macrocosm and the Crystalline Humor in the Three Eyes of Early Modern Optical Anatomy. Part II. The Revolution of the Eye and De-centering the Eyes Sovereign.
Ancient physicians based their practice of medicine on the humoral theory of disease. This theory posited that substances called humors make up the body and determine health and disease. When in balance, these humors - blood, yellow bile, black bile, and phlegm - caused health; out of balance, they caused disease. This theory also related humors to the 4 elements: earth, fire, water, and air. Of the humors, blood was unique in its content of all 4 elements.. Now relegated to the realm of quaint and discredited ideas of the past, the humoral theory of disease nevertheless has elements of truth. Importantly, this theory recognized the importance of blood in disease pathogenesis and the diversity of bodily constituents that can influence disease. With scientific advance, earth, fire, water, and air have been replaced by cells, cytokines, chemokines, and prostanoids, among many others. The list of these substances is ever increasing, with disciplines of genomics, proteomics, metabolomics, and ...
New Delhi, Aug 18: In a desperate move, Indian PM Dr. Manmohan Singh has posted a query on Yahoo Answers asking for suggestions (and answers) from netizens on how to put his house in order after a spate of scandals and ill timed moves diminished the stature of his administration. Clearly, the onslaught by crusader Anna Hazare has shaken the PM and forced him to seek unconventional channels to find ways to put things back on track before the next general elections. When Humor Unplugged logged on to Yahoo answers today morning, we were shocked to see the posed by the beleagured Indian PM. The question was asked sometime in the morning and 4 people had already answered it when we last checked. Sources in the PMO whom we woke up early morning were tight lipped and grouchy and refused to comment on the news, even on the condi ...
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This is the place for related humour. There are times when it may be very tempting to share something funny, and it is tempting to do so wherever you are on the net. Please place/share it here to keep things on track elsewhere (and help others resist a reciprical response) and leave it here for prosperity. Thanks.
I was cleaning out the old junk folder and found a real message that had ended there. (Happily, thats so rare these days that I dont check constantly anymore.) Anyway, h.t. to j.c. for a message that contained a suggestion for a bit of font humor. If you love Comic Sans, this may make your day ...
After 21 years, the Annals of Improbable Research -- that bastion of uber-nerdy science humour -- is switching from a dead tree format to an all-digital...
I think if you really believe in something, the best way for the writer, artist or songwriter to get the message across is to use humour, like we can see in this video.
WW2: Believe It, Or not! at Other. -- Created at 08/06/2016, 23 Replies - Humour Zone -- Indias Fastest growing Online Shopping Community to find Hottest deals, Coupon codes and Freebies.
A treatment for glaucoma that involves destruction of some of the ciliary processes in order to reduce production of aqueous humor. This process is sometimes referred to as cycloablation or (when done with a laser) cyclophotodestruction ...
Thank you for sharing such a detailed and intimate account of your miscarriage. Im currently in the middle of finishing up my fourth. My hcg always takes *forever* to fall, so I bleed for weeks and weeks afterwards. Every time, my doctor comes up with a new diagnosis to explain things and try to treat to prevent the next one. First PCOS, then hypothyroidism, and this time theyve figured I have a thrombophilia. Im the type to deal with it with my private sorrow on the inside and flippant dark humor on the outside. I cant not tell my friends when I get pregnant, but its getting a little tedious to have to take it back later. Im thinking of announcing the next pregnancy with, Hey guys! Ive started growing my next miscarriage! Fortunately, my friends share my sense of humor. You just cant know how much I appreciate you telling of your dark desire to kick pregnant women. My partner and I shared those types of thoughts, too. In the store, wed mutter nervously to one another about kicking ...
Filmmaker and Academy Award-nominated screenwriter Paul Weitz turns his complex sense of humor on Synergy, an insightful comedy about the relationship between a 50-year-old businessman and his new,...
Apr 12, 2012 Do animals have a sense of humor? Of course they do. Not only can they sense our humor, but they also have a sense of their own. I was... read more ...
You have a passionate desire to help your fellow man. Unfortunately, those who know you best - your friends and loved ones - may find that your personality is much too salty, and their criticism will probably affect you deeply because you are really much softer than you appear. You should go right ahead and marry anybody you want to because in a certain way, yours is a charmed life. On the road of life, you can be sure that people will always pull over and stop for you ...
It was rough here last week in Cambridge, MA and I just couldnt focus on the tasks at hand. So I stumbled upon what seemed like just the right combination of sensitivity,…. ...
Type: Humor, Reference Mr Osbornes style, wit, and humor makes this not only an interesting read, but a true joy. A rare example of prose and style that will delight anyone who reads and drinks - preferably at the same time.. ...
In the aftermath of brain injury, to battle my stress and despair, I joked about myself and my situation. It was especially effective when others joined in, but not everyone did.
Updated) If men are funnier than women, then its not by much - and mostly just to other men. Such is the conclusion of a …. ...
Dear Ely,. This loser I work with keeps asking me out, and its really annoying. Im a total hottie and hes a complete geek, so he really ought to know better. I mean, I do flirt with him sometimes. But thats only because he controls the office supplies and Im always in need of extra white-out. (I make a lot of mistakes, and I like to sniff it!) He should realize Im just using him, yet he persists in asking for dates. I cant just shoot him down for fear hell cut off my white-out supply, so I always make up some obviously phony excuse for why I cant see him this week.... Read More ...
I have worked for a bank, and I now work for a federally-insured credit union now. There is a well-known scheme called the Bank Examiner Scam: an official visits a depositor, usually an elderly person, to say that her help is needed to trap an employee at her bank who has been ripping off customers. All she has to do is make a large cash withdrawal, then hand it over to the official, to be used as evidence. She is assured that there is no risk, shell get her cash back, but not to answer any questions about the withdrawal, as this would tip off the criminal employee. If the scam is successful, the official takes the money and is never heard from again. Often, once the victim realizes it was a con, he or she is too embarrassed at being fooled to report the crime, which allows the con artist to continue operating ...
jake: I like the billboard because its bound to get people who dont know the station and have a sense of humor curious enough to tune in. I know if I didnt already know the station and saw it, Id tune in immediately just to know wtf this station was all about and then Id be drawn in and become a listener and therein lies donations and all that. But then not everyone has that kind of sense of humor/tolerance for weirdness ...
I also received the new Extranjero. It looks like Kris and Lola take a trip to the US in this text-packed issue. I am going to save this one for my trip to Germany next week because I see the humor in reading a zine by a US expat wholives in Europe, but writing about traveling in the US while traveling in Europe myself. I never said I had a developed sense of humor ...
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Almost eight years to the day. Ive hoarded this card in my top desk drawer and once or twice a year I have searched the internet for them ...
General CommentI definitely agree with the Chrons Disease comment. This song is Daryl, on the brink of becoming an Atheist, as a final message to God. After not being answered for being damned with Chrons, he basically tells God that hes got a fucked up sence of humor and gives God a sarcastic "Thanks, Buddy." Its so obvious that God has to agree about his humor ...
Almost eight years to the day. Ive hoarded this card in my top desk drawer and once or twice a year I have searched the internet for them ...
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Internal standard capsules. Kit includes 3H for organic samples, 3H for aqueous samples, 14C for organic samples, and 14C for aqueous samples.
Newzealandske Taika Waititi delte vandene, men vandt publikumsprisen på årets filmfestival i Toronto for sin satiriske komedie Jojo Rabbit, der med humor som våben udstiller had, nationalisme og blind loyalitet, og opfordrer os til at tænke selv.
themedihealth.com strives to ensure a better tomorrow by providing valuable and reliable health information to the users. It also gives knowledge about the environment & its facts through gogreen section, helps users to relax through humor section and inspires the users through inspirational quotes section
Telegraph Dating Member Profile: fisc01 - Never Too Old to Start Afresh. I have a very young outlook on life and, am told, an excellent sense of humour. I...
Throwrug was a Bellingham, WA zine published throughout the 1990s. Each issue had a hodgepodge of content from band interviews and reviews to pop culture analysis and humor. ...
Havent watched the Simpsons in a long time, but I remember Angry Dad: that was the subject of a parody during the dot-com boom about a decade ago.. Thanks to EW.com, which notes "Its not often that the visuals in The Simpsons, always intentionally, artfully crummy, top the verbal humor, usually intentionally wittier than the visuals." Eh? The art hasnt been intentionally crummy in a long time. If anything, long-time fans lament how clean its become, compared to the squiggly, loose-lined early years.. ...
Studies show good health is all important There are many variations of passages of Lorem Ipsum available, but the majority have suffered alteration in some form, by injected humour, or randomised words which dont look even slightly believable. If you are going to use a passage of Lorem Ipsum, you need to be sure there [...]. ...
Studies show good health is all important There are many variations of passages of Lorem Ipsum available, but the majority have suffered alteration in some form, by injected humour, or randomised words which dont look even slightly believable. If you are going to use a passage of Lorem Ipsum, you need to be sure there [...]. ...
The Black Table is updated daily with humor, essays, oddities, links, commentary and other random bits of gossip, trivia and fun.
I just woke up from a big old nap and I think Im in a good enough mood now to try and write a post. Ive been seriously lacking in good humor and whatever post I tried to write I had to delete because I was not happy with it. It think it is very possible that I was just plain grumpy all this time and that nothing at all made me happy. Its good to own up to this and to not beat around the bush. When grumpy, admit that you are. Its the easiest way to get back to feeling normal ...
For a while Ive been mulling over that being a repository manager is rather like being RoboCop. Yeah, I know Ive only just finished banging on how Babylon 5 is linked to the world of open access and repositories - some humour me okay as I go all SciFi on you. Again. If you dont…
Im so sorry that your sense of humour is MIA! While I understand that it may simply be a biological nasty, I would try a session of (please be...
Praise for Building Clustered Linux SystemsThe author does an outstanding job of presenting a very complicated subject. I very much commend this work. The author sets the pace and provides vital resources and tips along the way. He also has a very good sense of humor that is crafted in the text in such a way that makes the reading enjoyable just when the subject may demand a break.
Mrs. Bignuf says for her a guy must be intelligent, but possess humor. He must be mature and not whiny or needy. Above all, he must be HONEST (one...
LOL Alby used to ride my ass like there was no tomorrow, I have never met any1 as rotten hehehehe -But I have to admit the guy had a heck of a sense of humor!!
IM 61, ATHLETIC, DOWN TO EARTH, GREAT SENSE OF HUMOR, AND A COOL PERSON TO BE AROUND. SO IF UR LOOKIN FOR SOMEONE COOL THEN IM THAT GUY, SO LADIES HOLLA AT ME. I DONT BITE, UNLESS U WANT ME TOO LOL. ANYTHING ELSE U WANNA KNOW ABOUT ME THAT I MIGHTVE LEFT OUT, GET AT ME TO FIND THEM OUT ...
Plot twists, surprising humour, and an assembly of great character actors await you in this stylish thriller from the brothers Coen.
There are plenty of reasons for the success of Chuck Lorres The Big Bang Theory. The show is unique in that the majority of humor is…
Please see the satire below. It is located on page 42 and is titled The Passing of Grandison . I am a little confused and need help explaining 1) How humor plays a role in the story? 2) What other meaning might passing take on.
Dont miss out on EdWorlds new guide. Humor, connections and self-reflection go a long way in ensuring that youll have a great year! These tips ...
ISOLUTE® C18 is a retentive, non-polar sorbent for extraction of a range of analytes from aqueous samples using a non-polar retention mechanism.
We report here the results of our experience with the use of PCR for the identification of T. gondii in blood and aqueous humor samples from patients with and without ocular toxoplasmosis. Currently, the clinical diagnosis of ocular toxoplasmosis is based on the observation of a necrotizing lesion on the fundus, response to treatment, and serologic determination. However, in cases of atypical retinitis or when the fundus is hidden by vitreal inflammation, establishment of a diagnosis by ophthalmological examination alone can be difficult. In such cases the aqueous humor analysis may be used as a diagnostic tool for confirmation of ocular toxoplasmosis. Determination of intraocular production of antitoxoplasmic antibodies has been performed previously, but the results obtained had erratic values (2, 21). PCR has mostly been used to detect T. gondii in different biological samples (4, 9, 12, 14,19). Aqueous humor samples from patients with ocular toxoplasmosis have also been used with the PCR ...
In our study, 2PM was used to image the trabecular drainage channels of intact enucleated rat eyes. Due to the intrinsic properties of drainage tissue, autofluorescence from collagen fibers can be used to image the microstructure of the pathway. Compared to external fluorescent label, autofluorescence can avoid tissue damage caused by fluorochrome. Meanwhile, 2PM is suited to tissue imaging under the sclera, and has been successfully used to image living skin at a depth of 350 μm by visualizing the 2PAF of the skins extracellular matrix and melanin [19]. Most importantly of all, we were able to successfully get the high resolution images under high scattering tissue of eye. Our imaging had a lateral resolution of 2 μm, and a depth resolution of 1 μm. It is found that the high resolution imaging can achieve resolution of tissue section, and can avoid tissue distortions caused by infusion of fixatives.. Aqueous humor drains into aqueous vein through TM region firstly. In this progress, TM and ...
The major risk factor for most glaucomas and focus of modeling and treatment is increased intraocular pressure. Intraocular pressure is a function of production of liquid aqueous humor by the ciliary body of the eye and its drainage through the trabecular meshwork. Aqueous humor flows from the ciliary bodies into the posterior chamber, bounded posteriorly by the lens and the zonule of Zinn and anteriorly by the iris. It then flows through the pupil of the iris into the anterior chamber, bounded posteriorly by the iris and anteriorly by the cornea. From here the trabecular meshwork drains aqueous humor via Schlemms canal into scleral plexuses and general blood circulation. In open angle glaucoma there is reduced flow through the trabecular meshwork; in angle closure glaucoma, the iris is pushed forward against the trabecular meshwork, blocking fluid from escaping ...
Interest in the linguistics of humor is widespread and dates since classical times. Several theoretical models have been proposed to describe and explain the function of humor in language. The most widely adopted one, the semantic-script theory of humor, was presented by Victor Raskin, in 1985. Its expansion, to incorporate a broader gamut of information, is known as the General Theory of Verbal Humor. Other approaches are emerging, especially in cognitive and corpus linguistics. Within applied linguistics, the predominant approach is analysis of conversation and discourse, with a focus on the disparate functions of humor in conversation. Speakers may use humor pro-socially, to build in-group solidarity, or anti-socially, to exclude and denigrate the targets of the humor. Most of the research has focused on how humor is co-constructed and used among friends, and how speakers support it. Increasingly, corpus-supported research is beginning to reshape the field, introducing quantitative concerns, as well
Our image of Roman satire has developed from that of a static, moralizing genre to a deliberately complex form, but our approach to the humour intrinsic to satire has not developed accordingly. This book offers a comprehensive new analysis of humour in the writings of Horace, Persius, and Juvenal, with an excursus to Lucilius. The main thesis is that far from being an external means of sweetening the moral lesson, humour lies at the heart of Roman satire and shapes its paradoxical essence. The book argues that while the satirist needs humour for the aesthetic merit of his work, his ideological message inevitably suffers from the ambivalence that humour carries. By analyzing object-oriented humour, humour directed at the speaker (including self-irony), and humour directed at neither object nor subject, the book shows how the Roman satirists work round this double mission of morals and merriment. As a result, they present the reader with a much more sprawling and open literary product than they promise
Aim: To measure the genomic DNA of human herpes viruses (HHV) in the ocular fluids and to analyze the clinical relevance of HHV in uveitis. Methods: After informed consent was obtained, a total of 111 ocular fluid samples (68 aqueous humor and 43 vitreous fluid samples) were collected from 100 patients with uveitis. The samples were assayed for HHV-DNA (HHV1-8) by using two different polymerase chain reaction (PCR) assays, qualitative PCR (multiplex PCR) and quantitative PCR (real-time PCR). Results: In all of the patients with acute retinal necrosis (n=16) that were tested, either the HSV1 (n=2), HSV2 (n=3), or VZV (n=11) genome was detected. In all patients, high copy numbers of the viral DNA were also noted, indicating the presence of viral replication. In another 10 patients with anterior uveitis with iris atrophy, the VZV genome was detected. When using multiplex PCR, EBV-DNA was detected in 19 of 111 samples (17%). However real-time PCR analysis of EBV-DNA indicated that there were only 6 ...
Read "Isoforms of TGF-β in the aqueous humor of patients with pseudoexfoliation syndrome and a possible association with the long-term stability of the capsular bag after cataract surgery, Graefe
Levels of Aqueous Humor Trace Elements in Patients with Non-Exsudative Age-related Macular Degeneration: A Case-control Study. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
A device and method are provided for improved treatment of elevated intraocular pressure due to glaucoma. A trabecular shunting device is adapted for implantation within the trabecular meshwork of an eye such that aqueous humor flows controllably from the anterior chamber of the eye to Schlemms canal, bypassing the trabecular meshwork. The trabecular shunting device may utilize a quantity of pharmaceuticals effective in treating glaucoma, which are controllably released from the device into cells of the trabecular meshwork and/or Schlemms canal. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular shunting device such that aqueous flow either increases or decreases as desired. Placement of the trabecular shunting device within the eye, and release of a glaucoma medication therefrom, can arrest or slow the progression of glaucoma.
This study has outlined the rate and duration of penetration of tritiated prednisolone into the aqueous humor following a single clinical dose. The prednisolone
ធម្មតា ការផលិតទឹកក្នុងភ្នែករបស់យើង (Aqueous humour) ចាប់ផ្តើមចេញពីគល់ប្រស្រីភ្នែក (Ciliary body) ដែលជាកន្លែងផលិត បន្ទាប់មកវាហូរមកបន្ទប់ផ្នែកខាងក្រោយ រួចបន្តមកបន្ទប់ភ្នែកខាងមុខ ហើយត្រូវបានស្រូបចេញតាមចម្រោះ Trabecular Meshwork និងបន្តចេញមកតាម បំពង់តូច (Schlemms canal) ហើយចុងបញ្ចប់ជ្រាបតាមសរសៃវ៉ែន (Episcleral vein) ...
Looking for Humor, Vampire? Find out information about Humor, Vampire. Mel Brookss Dracula: Dead and Loving It is a prime example of vampire humor. Leslie Neilsen played the hapless Count Dracula. Legendary Dracula actor... Explanation of Humor, Vampire
A new study shows that patients with glaucoma or ocular hypertension (OHT) and recurrent anterior uveitis have a reduced tonographic outflow-lower than patients without glaucoma or OHT-but an actual aqueous flow that is not statistically any different from patients without glaucoma or OHT. Researchers from St. Thomas Hospital in London divided 92 patients into three groups. Group one had patients with recurrent anterior uveitis (three or more attacks) and were being treated for glaucoma or OHT. Group two patients had experienced previous recurrent anterior uveitis without glaucoma or OHT. The third group, the controls, had no ocular problems and IOP less than 21mm Hg. They found that the tonographic outflow facility was approximately 0.18 in group one, 0.25 in group two and 0.27 in the control group. However, the aqueous flow rate in group one was 2.47μl/min, in group two it was 2.13μl/min and 2.25μl/min in the control. The investigators say this demonstrates that the elevated IOP seen in the ...
Contemporary research began investigating the physiology and therapeutic effects of humor and in fact some believe that humor accomplishes the same goal as physical exercise. Some humor -laughter research findings are as follows:1. Humor experience leads to arousal of the sympathetic nervous system 2.Epinephrine is a precondition for physiological arousal 3. Arousal as measured by heart rate and skin conduction increases with the intensity of the response to something humorous 4. Laughter increases respiration, oxygen exchange, muscular activity, heart rate , stimulates the cardiovascular system , the sympathetic nervous system and the production of catecholamine 5. Blood-pressure is also reduced in a state similar to that resulting from exercise. 6. Increases in systolic and a diastolic blood-pressure is related to the intensity and length of the laughter .Blood pressure levels decreased after laughter to below pre-laughter levels.7 There is greater coordination of function between the right ...
The Kahook Dual Blade (KDB) is an single-use ophthalmic blade with a micro-engineered profile which allows for insertion into the eye through a clear cornea micro-incision. It can be done with or without cataract surgery, and when done in conjunction with cataract surgery it is done following lens removal through the same incision utilized for the cataract removal. The device is made of surgical grade stainless steel body with a long, thin shaft that allows for access across the anterior chamber to the trabecular meshwork (TM). Using a special mirrored lens, the surgeon uses the Kahook Dual blade to make parallel incisions in the trabecular meshwork (TM), un-roofing it and opening up into inner wall of the Canal of Schlemm to improve aqueous humor outflow from the eye in an effort to reduce the eye pressure. This procedure does not involve opening up the conjunctival tissues; this is a major advantage of this procedure as it makes future glaucoma surgery (if needed) a lot simpler with less risk ...
Deposition of extracellular matrix (ECM) in trabecular meshwork, such as fibronectin, collagen IV, elastin. leads to increased resistance of trabecular meshwork in primary open angle glaucoma (POAG). Connective tissue growth factor (CTGF) is known to regulate the ECM deposits. In this study, we detect the effect of adenovirus conducted CTGF (Adv-CTGF) transfection on either the expression of ECM components or aqueous humor outflow facility. Adv-CTGF was used to transfect rat trabecular meshwork cells in vivo and in vitro. Aqueous humor outflow facility was test by microbeads perfusion. Protein expression of CTGF, fibronectin, and collagen IV was determined using Western blot. In the Adv-CTGF group, the outflow facility displayed a significant decrease from baseline. It appears as though the transfection with Adv-CTGF significantly affects the aqueous humor outflow pattern. A negative correlation between IOP and PEFL indicated that a decrease in the area of bead deposition corresponded to an overall
We encountered a case of acute anterior uveitis with severe hyphema following ZSH in an immunocompetent woman. Several complications resulted, such as severe iris atrophy, decrease in corneal endothelial cell count, and secondary cataract necessitating operation.. A definitive diagnosis of ZSH can be made by detecting viral DNA in aqueous humor [6], but antibody examination is also useful in diagnosis [7]. In this case, PCR was performed three months after onset when inflammation had almost resolved, and the result was negative. We did not perform anterior chamber paracentesis while hyphema was present to avoid aggravating the hyphema. Delay of the procedure might be the reason that VZV-DNA was not detected by PCR. We next attempted to detect virus-specific antibody in the aqueous humor. Even at 9 months after onset, anti-VZV IgG (EIA) in the aqueous humor was approximately 10-fold higher than the serum level. Because an antibody ratio equal to or higher than 1.0 suggests local antibody ...
TY - JOUR. T1 - Measurement of episcleral venous pressure. AU - Sit, Arthur J. AU - McLaren, Jay W.. PY - 2011/9. Y1 - 2011/9. N2 - Episcleral venous pressure (EVP) is an important determinant of intraocular pressure (IOP) and can be measured by using various techniques. It has been measured non-invasively by estimating the pressure required to compress an episcleral vein to a predetermined endpoint. However, the lack of objective endpoints makes EVP measurement in humans uncertain, and a wide range of mean EVP has been reported in the literature. We review the evidence for physiologic regulation of EVP and its role in glaucoma therapy, techniques that have been used to measure EVP and the need for objective measurements, and reported values for EVP. We also review recent progress toward developing an objective technique for EVP measurement.. AB - Episcleral venous pressure (EVP) is an important determinant of intraocular pressure (IOP) and can be measured by using various techniques. It has ...
Glaucoma is a chronic progressive disease of the optic nerve which, if not treated, leads to visual field decay and blindness at end stages. Intraocular pressure (IOP) decreasing is shown to diminish the progression of the disease, and could be achieved by the chronic use of hypotensive eyedrops, incisional surgery or laser trabeculoplasty. There is still great controversy about where in the treatment scale laser trabeculoplasty is positioned, although this technique has already been described three decades ago. This treatment consists of application of laser spots in the trabecular meshwork, the structure responsible for the aqueous humor drainage, leading to an increase in the outflow facility through it and in consequence, decreasing IOP. It is an interesting form of treatment since it does not depend on chronic instillation of eyedrops, as does medical treatment, and also does not have too many complications, as does incisional surgery. This review included 19 trials (2137 participants). One ...
The aim of the present study was to examine whether children with Aspergers syndrome differ from typically developing children in the appreciation of and behavioral responses to simple slapstick type humor, in which cognitive requirements that are commonly impaired in autism spectrum disorders are reduced to a minimum. Short slapstick scenes and matched non-humorous control scenes were extracted from popular movies to produce an appropriate humor assessment material. Twenty-four boys with Aspergers syndrome (5 to 14 years) and 24 age-matched typically developed controls were tested. The results indicated that children with Aspergers syndrome enjoy humorous material as much as healthy children do, if the humor elements are simple and the incongruence can be perceived independently from theory of mind requirements, inferential demands, or language abilities. However, similar funniness ratings and behavioral expressions of mirth to the humorous scenes, but relatively higher values in response to ...
TY - JOUR. T1 - The effect of dexamethasone on glycosaminoglycans of human trabecular meshwork in perfusion organ culture. AU - Johnson, D. H.. AU - Bradley, J. M B. AU - Acott, Ted. PY - 1990. Y1 - 1990. N2 - The effect of dexamethasone treatment on glycosaminoglycans (GAG) in the human trabecular meshwork was studied by placing 20 pairs of eyes in perfusion organ culture. One eye received 550 nM dexamethasone in addition to culture medium; the fellow eye received culture medium only. 3H-glucosamine and 35S-sulfate were added to the medium for the final 48 hr of culture. The meshwork was then dissected, and the GAGs were isolated and subjected to sequential enzymatic degradation. Active labeling of hyaluronic acid, chondroitin sulfate, dermatan sulfate, keratan sulfate, and heparan sulfate was found in both control and steroid-treated eyes. Dexamethasone-treated eyes had an average 92% increase in the 3H-glucosamine incorporation rate in the undigestible GAG residue fraction after 14-21 days ...
TY - JOUR. T1 - Intraocular pressure elevation in uveitis. AU - Md. Din, Norshamsiah. AU - Mohd Isa, Hazlita. AU - Taylor, Simon R J. AU - Barton, Keith. AU - Lightman, Susan L.. PY - 2012/2. Y1 - 2012/2. N2 - Raised intraocular pressure in uveitis, either due to the disease itself or secondary to treatment with steroids, is one of the most common causes of secondary glaucoma in clinical practice. There are currently no standardized criteria for the diagnosis nor guidelines for the management of raised intraocular pressure in uveitis. Intraocular pressure elevation may be due to any combination of several mechanisms and, as a result, the prognosis differs from primary glaucomas. In addition, the management of ongoing inflammation without elevating the intraocular pressure remains a challenge. Ideally, new anti-inflammatory agents should have better anti-inflammatory properties with safer intraocular pressure profiles, while sustained release medications to lower intraocular pressure would ...
Glaucoma in the first decade of life should be thoroughly evaluated for an ocular neoplasm. Up to 17%-22.8% of patients with retinoblastoma have increased intraocular pressures typically due to iris neovascularization.(6,7) However, with diffuse infiltrating retinoblastoma subtypes, glaucoma can result from neoplastic seeding of the trabecular meshwork in the anterior chamber, causing outflow obstruction of the aqueous humor.(6). Retinoblastoma has 4 different growth patterns: endophytic growth toward the vitreous, exophytic growth toward the choroid, mixed exophytic and endophytic growth (most common), and diffuse infiltrating growth. Diffuse infiltrating retinoblastoma is rare, accounting for only 1%-2% of all cases,(1,8) and is characterized by plaquelike thickening of the retina without a discrete mass lesion. Patients often present when pseudoinflammatory complications occur once the lesion infiltrates into the anterior segment, and the condition may be misdiagnosed as uveitis and ...

Glaucoma in Fuchs heterochromic cyclitis associated with congenital Horners syndromeGlaucoma in Fuchs' heterochromic cyclitis associated with congenital Horner's syndrome

We investigated the synthesis of RV-specific IgG using aqueous humor and serum samples from 63 consecutive patients with FHC. ... Purpose: Uveitis is the inflammation of the uveal tract, which usually also affects the retina and vitreous humor. The ...
more infohttp://connection.ebscohost.com/c/articles/66097524/glaucoma-fuchs-heterochromic-cyclitis-associated-congenital-horners-syndrome

Monitoring herpesviruses DNA in three cases of acute retinal necrosis by real-time PCR<...Monitoring herpesviruses DNA in three cases of acute retinal necrosis by real-time PCR<...

The herpes simplex virus (HSV)-2 viral load in aqueous humor remained stable (2.3×103 to 2.8×103 copies/ml) during the first 3 ... The herpes simplex virus (HSV)-2 viral load in aqueous humor remained stable (2.3×103 to 2.8×103 copies/ml) during the first 3 ... The herpes simplex virus (HSV)-2 viral load in aqueous humor remained stable (2.3×103 to 2.8×103 copies/ml) during the first 3 ... The herpes simplex virus (HSV)-2 viral load in aqueous humor remained stable (2.3×103 to 2.8×103 copies/ml) during the first 3 ...
more infohttps://pure.fujita-hu.ac.jp/en/publications/monitoring-herpesviruses-dna-in-three-cases-of-acute-retinal-necr

Aqueous humor cytokine profiling in patients with wet AMD.  - PubMed - NCBIAqueous humor cytokine profiling in patients with wet AMD. - PubMed - NCBI

Aqueous humor cytokine profiling in patients with wet AMD.. Liu F1, Ding X1, Yang Y1, Li J1, Tang M1, Yuan M1, Hu A1, Zhan Z1, ... Undiluted aqueous humor samples (100-200 μl) were obtained from 16 wet AMD eyes and 12 control eyes. Forty chemokines were ... Compared with the control group, the aqueous humor in wet AMD patients showed a significantly higher expression of CXCL10 (p= ... To investigate the chemokine expression profiles in the aqueous humor of wet age-related macular degeneration (wet AMD) ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/27122966

Patent US7811268 - Device for draining aqueous humor in cases of glaucoma - Google PatentsPatent US7811268 - Device for draining aqueous humor in cases of glaucoma - Google Patents

... the aqueous humor is drained.. Consistently with the laws of physics, the aqueous humor contained in the chamber with the ... aqueous humor can circulate from the concave lower part towards the convex upper part, creating two spaces of aqueous humor to ... Aqueous humor drainage device. US4750901. Mar 5, 1987. Jun 14, 1988. Molteno Anthony C B. Implant for drainage of aqueous ... Glaucoma aqueous humor drainage plate. EP0168201A1. Jun 27, 1985. Jan 15, 1986. Neil Howard Joseph. Aqueous humour drainage ...
more infohttp://www.google.com/patents/US7811268?dq=6462713

Aqueous humor biopsy for retinoblastoma shows promise  - American Academy of OphthalmologyAqueous humor biopsy for retinoblastoma shows promise - American Academy of Ophthalmology

This study finds that aqueous humor from retinoblastoma eyes contains tumor-derived DNA that can be analyzed as an alternative ... Aqueous humor biopsy may be an improvement over existing methods, as it could require less advanced technical skills and carry ... Evaluation of aqueous humor demonstrated tumor-derived, cell-free DNA and regions of chromosomal gains and losses, representing ... This study finds that aqueous humor from retinoblastoma eyes contains tumor-derived DNA that can be analyzed as an alternative ...
more infohttps://www.aao.org/editors-choice/aqueous-humor-biopsy-retinoblastoma-shows-promise

Effects of Selective Laser Trabeculoplasty on Aqueous Humor Dynamics - Full Text View - ClinicalTrials.govEffects of Selective Laser Trabeculoplasty on Aqueous Humor Dynamics - Full Text View - ClinicalTrials.gov

Effects of Selective Laser Trabeculoplasty on Aqueous Humor Dynamics. The safety and scientific validity of this study is the ... This study will determine the changes in aqueous humor dynamics produced by SLT that lead to its IOP lowering effect. SLT is a ... The effect of SLT on the aqueous humor dynamics is currently unknown. Given the lack of demonstrable thermal damage on ... This study will compare aqueous humor dynamics in adults with primary open angle glaucoma that receive Selective Laser ...
more infohttps://clinicaltrials.gov/ct2/show/NCT01342406

CiNii 論文 - 
 		
 		
 			
 		 	
 		 		
 		 			Human Hepatocyte Growth Factor (HGF) in the Aqueous Humor
 		 		
 		 		
 		 	
 		
...CiNii 論文 - Human Hepatocyte Growth Factor (HGF) in the Aqueous Humor ...

Detection, quantification, and signficance of basic fibroblast growth factor in the aqueous humor of man, cat, dog and pig ... Human Hepatocyte Growth Factor (HGF) in the Aqueous Humor * * ARAKI SASAKI Kaoru ... Presence of human epidermal growth factor, basic fibroblast growth factor in human aqueous 並木真理 ...
more infohttps://ci.nii.ac.jp/naid/10018023057

Imaging Aqueous Humor Outflow   - EyetubeImaging Aqueous Humor Outflow - Eyetube

... sheds light on the importance of understanding aqueous outflow at a fundamental level and discusses aqueous humor outflow ... Huang comments on how aqueous angiography facilitates surgeons ability to place surgerie… ... sheds light on the importance of understanding aqueous outflow at a fundamental level and discusses aqueous humor outflow ... sheds light on the importance of understanding aqueous outflow at a fundamental level and discusses aqueous humor outflow ...
more infohttps://eyetube.net/meeting-coverage/los-angeles-2017-may/video.asp?f=htjop

Free radicals in the aqueous humor of patients with glaucoma | OPTHFree radicals in the aqueous humor of patients with glaucoma | OPTH

... or catalase was added to the aqueous humor and compared with aqueous humor in which SOD or catalase was not added.Results: In ... L-ascorbic acid likely has an antioxidative function in the non-NVG group, suggesting that the aqueous humor in the NVG group ... Free radicals in aqueous humor were detected by measuring the electron spin resonance (ESR). To identify free radical species, ... Free radicals in the aqueous humor of patients with glaucoma Eiki Oshida, Yukihiro Matsumoto, Kiyomi Arai1Department of ...
more infohttps://www.dovepress.com/free-radicals-in-the-aqueous-humor-of-patients-with-glaucoma-peer-reviewed-article-OPTH

Aqueous humor lidocaine concentrations in topical and intracameral anesthesiaAqueous humor lidocaine concentrations in topical and intracameral anesthesia

Lidocaine concentration was measured in aqueous humor samples taken before surgery. RESULTS: With 3 drops, aqueous lidocaine ... Aqueous humor lidocaine concentrations in topical and intracameral anesthesia. Behndig, Anders Umeå University, Faculty of ... PURPOSE: To assess aqueous humor lidocaine concentrations in 2 common regimens of topical anesthesia and after intracameral ...
more infohttp://umu.diva-portal.org/smash/record.jsf?pid=diva2:320685

The lens influences aqueous humor levels of transforming growth factor-beta 2.The lens influences aqueous humor levels of transforming growth factor-beta 2.

Aqueous Humor / metabolism*. Biological Assay. Cataract / etiology, metabolism, pathology. Cells, Cultured. Ciliary Body / ... Furthermore, aqueous humor from canine eyes with cataracts also contained significantly higher levels of TGF-beta 2 than normal ... Surprisingly, aqueous humor from aphakic rabbit eyes contained significantly higher levels of TGF-beta 2 than their ... METHODS: Lens and ciliary body epithelial cell culture supernatants and aqueous humors were assayed for total TGF-beta 2 levels ...
more infohttp://www.biomedsearch.com/nih/lens-influences-aqueous-humor-levels/9561366.html

Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients - Full Text View - ClinicalTrials.govAbsorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients - Full Text View - ClinicalTrials.gov

Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients. The safety and scientific validity of ... Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients.. ... The aqueous humor concentration 45 minutes following dosing of 0.1% Brimonidine Purite™ (pH 7.8) is comparable with 0.15% ... The purpose of this study is to obtain and assay human aqueous samples following pre-operative dosing with 0.1% Brimonidine ...
more infohttps://www.clinicaltrials.gov/ct2/show?term=Brimonidine&rank=38

CiNii 論文 - 
 		
 		
 			
 		 	
 		 		
 		 			Quantitative Analyses of Cytomegalovirus Genome in Aqueous Humor of Patients with...CiNii 論文 - Quantitative Analyses of Cytomegalovirus Genome in Aqueous Humor of Patients with...

Quantitative Analyses of Cytomegalovirus Genome in Aqueous Humor of Patients with Cytomegalovirus Retinitis * * ANDO Yasutaka ... Aqueous and vitreous humor samples for the diagnosis of cytomegalovirus retinitis MITCHELL SM ... An improved technique for the diagnosis of retinitis from samples of aqueous humor and vitreous GARWEG J ... Use of polymerase chain reaction assays of aqueous humor in the differential diagnosis of retinitis in patients infected with ...
more infohttps://ci.nii.ac.jp/naid/10013890764

Molecular Vision: Serotonin levels in aqueous humor of patients with primary open-angle glaucomaMolecular Vision: Serotonin levels in aqueous humor of patients with primary open-angle glaucoma

Serotonin levels in aqueous humor of patients with primary open-angle glaucoma. V. Zanon-Moreno,1 P. Melo,2 M.M. Mendes-Pinto,2 ... Aqueous humor samples of each patient were obtained by paracentesis at the beginning of the surgical procedures. 5-HT and 5- ... The purpose of this study is to evaluate the 5-HT and 5-HIAA (5-hydroxiindolacetic acid) levels in the aqueous humor of ... levels in aqueous humor (AH) of patients with primary open-angle glaucoma (POAG) and patients with cataracts (used as the ...
more infohttp://www.molvis.org/molvis/v14/a251/

Immune Mediator Profile in Aqueous Humor Differs in Patients with Primary Acquired Ocular Toxoplasmosis and Recurrent Acute...Immune Mediator Profile in Aqueous Humor Differs in Patients with Primary Acquired Ocular Toxoplasmosis and Recurrent Acute...

... and the chemokine IL-8 comparing immune mediator concentrations in aqueous humor of patients with pOT (. ) and rOT (. ) and the ...
more infohttps://www.hindawi.com/journals/mi/2019/9356728/fig3/

Circadian Variation of Aqueous Humor Dynamics in Older Healthy Adults | IOVS | ARVO JournalsCircadian Variation of Aqueous Humor Dynamics in Older Healthy Adults | IOVS | ARVO Journals

... a time when aqueous humor production is naturally low, will require measurement of all variables of aqueous humor dynamics ... Circadian Variation of Aqueous Dynamics in Young Healthy Adults. In Vivo Assessment of Aqueous Humor Dynamics Upon Chronic ... Circadian Variation of Aqueous Humor Dynamics in Older Healthy Adults Cherie B. Nau; Mehrdad Malihi; Jay W. McLaren; David O. ... Aqueous Humor Flow Rate, μL/min Outflow Facility, μL/min/mm Hg EVP, mm Hg Uveoscleral Outflow, μL/min ...
more infohttps://iovs.arvojournals.org/article.aspx?articleid=2127881

PRIME PubMed | Polymerase chain reaction for the detection of Toxoplasma gondii within aqueous humor of experimentally...PRIME PubMed | Polymerase chain reaction for the detection of Toxoplasma gondii within aqueous humor of experimentally...

PubMed journal article Polymerase chain reaction for the detection of Toxoplasma gondii within aqueous humor of experimentally- ... Elevated interleukin 6 activity in aqueous humor of cats with uveitis.. *Toxoplasma gondii-specific antibodies in the aqueous ... Administration, OralAnimalsAntibodies, ProtozoanAqueous HumorBlotting, SouthernCat DiseasesCatsChorioretinitisDNA, Protozoan ... Serum and aqueous humor were collected from five SPF cats prior to oral inoculation with T. gondii and days 7, 14, 21, 28, 42, ...
more infohttps://www.unboundmedicine.com/medline/citation/9823058/Polymerase_chain_reaction_for_the_detection_of_Toxoplasma_gondii_within_aqueous_humor_of_experimentally_inoculated_cats_

Poly-Unsaturated Fatty Acids in Human Aqueous Humor | IOVS | ARVO JournalsPoly-Unsaturated Fatty Acids in Human Aqueous Humor | IOVS | ARVO Journals

... are present in human aqueous humor.. Methods: Undiluted aqueous humor samples were collected from 10 patients who underwent ... Poly-Unsaturated Fatty Acids in Human Aqueous Humor You will receive an email whenever this article is corrected, updated, or ... Results: The analysis of ten samples of aqueous humor demonstrated the presence of the omega-6 fatty acid linoleic acid (LA), ... Conclusions: We demonstrate the presence of omega-3 and omega-6 PUFAs in human aqueous humor. The omega-6 fatty acid, linoleic ...
more infohttp://iovs.arvojournals.org/article.aspx?articleid=2146666

Recurrence of toxoplasmic retinochoroiditis: Analysis of cases proven by initial analysis of aqueous humorRecurrence of toxoplasmic retinochoroiditis: Analysis of cases proven by initial analysis of aqueous humor

... ... Methods40 consecutive cases of TRC with a positive aqueous humour (AH) tap for toxoplasmosis were retrospectively included. ...
more infohttps://insights.ovid.com/acoph/201308001/01329159-201308001-00195

Effect of NSAIDs on Pupil Diameter and Expression of Aqueous Humor Cytokines in FLACS Versus Conventional PhacoemulsificationEffect of NSAIDs on Pupil Diameter and Expression of Aqueous Humor Cytokines in FLACS Versus Conventional Phacoemulsification

... and TNF-β in the aqueous humor of patients undergoing femtosecond laser-assisted cataract surgery (FLACS) and corneal ... Aqueous humor was obtained at a different time point in the FLACS and corneal paracentesis groups. This was unavoidable due to ... The aqueous humor was assayed to determine the concentrations of cytokines using the FlowCytomix human Th1/Th2 11-plex BMS810FF ... Others have shown that concentrations of IL-1β, IL-6, and PGE2 in aqueous humor increase during FLACS compared to controls.5. ...
more infohttps://www.healio.com/ophthalmology/journals/jrs/2018-10-34-10/%7B1047dfee-932e-4af7-a0a6-e96b73a52424%7D/effect-of-nsaids-on-pupil-diameter-and-expression-of-aqueous-humor-cytokines-in-flacs-versus-conventional-phacoemulsification

US7699882B2 - Apparatus and method for surgical bypass of aqueous humor 
        - Google PatentsUS7699882B2 - Apparatus and method for surgical bypass of aqueous humor - Google Patents

Since the aqueous humor passes directly into the venous system, the normal drainage process for aqueous humor is restored. ... may be connected to any source of aqueous humor, including the anterior chamber ( 1 ), an aqueous collector channel, Schlemms ... within the tissues of the eye to directly connect a source of aqueous humor such as the anterior chamber ( 1 ), to an ocular ... The invention provides minimally invasive microsurgical tools and methods to form an aqueous humor shunt or bypass for the ...
more infohttps://patents.google.com/patent/US7699882B2/en

Product Details for The Eyes Aqueous Humor: From Secretion to Glaucoma by Civan, Mortimer M.Product Details for The Eye's Aqueous Humor: From Secretion to Glaucoma by Civan, Mortimer M.

Buy The Eyes Aqueous Humor: From Secretion to Glaucoma by Civan, Mortimer M. at TextbookX.com. ISBN/UPC: 9780121746759. Save ... Description: This volume present a basic consensus of how the aqueous humor is formed and exits through the trabecular meshwork ... The Eyes Aqueous Humor: from Secretion to Glaucoma. by Civan, Mortimer M.. ... The Eyes Aqueous Humor: from Secretion to Glaucoma. by Civan, Mortimer M.. ...
more infohttps://www.textbookx.com/book/The-Eyes-Aqueous-Humor-From-Secretion-to-Glaucoma/9780121746759/

Toxocara-Specific Antibody in the Serum and Aqueous Humor of a Patient with Presumed Ocular and Visceral Toxocariasis* | The...Toxocara-Specific Antibody in the Serum and Aqueous Humor of a Patient with Presumed Ocular and Visceral Toxocariasis* | The...

... and in whom Toxocara-specific antibodies were also demonstrated in the aqueous humor. Two older siblings of this patients also ... Toxocara-Specific Antibody in the Serum and Aqueous Humor of a Patient with Presumed Ocular and Visceral Toxocariasis * * ... and in whom Toxocara-specific antibodies were also demonstrated in the aqueous humor. Two older siblings of this patients also ...
more infohttp://www.ajtmh.org/content/journals/10.4269/ajtmh.1979.28.29

Value of PCR for Detection of Toxoplasma gondii in Aqueous Humor and Blood Samples from Immunocompetent Patients with Ocular...Value of PCR for Detection of Toxoplasma gondii in Aqueous Humor and Blood Samples from Immunocompetent Patients with Ocular...

For blood and aqueous humor samples, 5 ml of anticoagulated blood and a 200- to 300-μl portion of aqueous humor, respectively, ... We report here the results of our experience with the use of PCR for the identification of T. gondii in blood and aqueous humor ... 1993) Detection of Toxoplasma gondii in aqueous humor by the polymerase chain reaction. Br. J. Ophthalmol. 77:107-109. ... The PCR was positive for 8 of the 15 blood samples and 7 of the 15 aqueous humor samples from patients in group 1. No ...
more infohttps://jcm.asm.org/content/37/11/3465
  • an inner diameter of between 0.3 mm and 0.4 mm and sufficient length to position the anterior end in the anterior chamber of the eye and the rear end having a size which fits within an area covered by a perimeter of the cover, located in the intrascleral space for drainage of the aqueous humor. (google.com)
  • It is called "open-angle" because the angle between the iris and the cornea is open, allowing drainage of the aqueous humor. (encyclopedia.com)
  • Quantitative analysis of the expressed cytokines in the aqueous humor was performed using FlowCytomix FC 500 Pro 3.0 Software (Bender MedSystems GmbH, Vienna, Austria). (healio.com)
  • Levels of various inflammation-related cytokines in the aqueous humor of using multiplex immunoassay. (arvojournals.org)
  • Assays of immune privilege markers in AqH reveal that mean TGF-β 2 content is abnormally low in patients coming to PK due to the high risk cases and that PK surgery results in a sustained loss of integrity of the blood-aqueous barrier. (egms.de)
  • The purpose of this study is to evaluate the 5-HT and 5-HIAA (5-hydroxiindolacetic acid) levels in the aqueous humor of patients with primary open-angle glaucoma (POAG). (molvis.org)
  • Typically in open angle glaucoma, the pathway for aqueous humor becomes narrowed or occluded, increasing IOP and resulting in gradual nerve damage and loss of vision. (google.com)
  • Aqueous humor was obtained from five human donors diagnosed with primary open angle glaucoma (POAG) and five age- and sex-matched controls undergoing cataract surgery. (physiciansweekly.com)
  • The aim of this study was to analyze concentrations of trace elements in aqueous humor samples of patients with primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG). (fau.de)
  • CONCLUSION: Significant differences in aqueous humor levels of zinc and iron between glaucoma and control patients support the hypothesis that these trace elements are involved in the pathogenesis of open-angle glaucoma. (fau.de)
  • To quantify the levels of tissue inhibitor of metalloproteinase 4 (TIMP4) and its ratios with free metalloproteinases (MMP) in the aqueous humor of patients with primary open angle glaucoma (POAG), pseudoexfoliation syndrome (PXS) and pseudoexfoliative glaucoma (PXG) and to evaluate a possible imbalance between MMPs and TIMPs in these samples. (biomedcentral.com)
  • Dr. Huang comments on how aqueous angiography facilitates surgeons' ability to place surgeries in customized locations for better intraocular pressure-lowering results. (eyetube.net)
  • Functional assessment focuses on visualizing AHO itself through a variety of non-real-time and real-time techniques such as aqueous angiography. (omicsonline.org)
  • Aqueous humor cytokine profiling in patients with wet AMD. (nih.gov)
  • The research was to evaluate cytokine profile in aqueous humor of congenital cataract with PCD to search the pathogeny of PCD. (arvojournals.org)
  • To compare the aqueous humor levels of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in high myopic eyes and control eyes. (molvis.org)
  • The aqueous humor levels of VEGF and PEDF were determined by using commercially available enzyme-linked immunosorbent assay kits. (molvis.org)
  • Aqueous humor levels of VEGF in the high myopia group were significantly lower than those in the control group. (molvis.org)
  • In this study, we classified the patients according to the severity of RPE degeneration and compared the aqueous levels of VEGF and PEDF in highly myopic and control eyes. (molvis.org)
  • This comparative control study investigated the aqueous humor levels of VEGF and PEDF in highly myopic eyes. (molvis.org)
  • Higher preoperative levels of TGFβ2, IL-6, VEGF in aqueous humor were associated with posterior capsule defect, which indicated the inflammation state in congenital cataract with posterior capsule defect. (arvojournals.org)
  • Analysis of VEGF and PlGF in the aqueous humor was performed before each injection in cases and prior to cataract surgery on 10 patients as included as controls. (unich.it)
  • In this prospective, randomized controlled, single-center study, aqueous humor samples were obtained immediately after performing the femtosecond laser procedure or at the start of conventional phacoemulsification. (healio.com)
  • This study finds that aqueous humor from retinoblastoma eyes contains tumor-derived DNA that can be analyzed as an alternative to tissue biopsy. (aao.org)
  • These findings suggest that aqueous humor can serve as a surrogate tumor biopsy for analyses of tumor-derived DNA in retinoblastoma eyes. (aao.org)
  • therefore, this study aimed to identify cfDNA in the aqueous humor (AH) of retinoblastoma eyes and correlate somatic chromosomal copy-number alterations (SCNA) with clinical outcomes, specifically eye salvage. (aacrjournals.org)
  • The humor plays a crucial role in supporting the posterior side of the lens. (wikipedia.org)
  • To investigate the penetration of 0.3% gatifloxacin ophthalmic gel, 0.3% gatifloxacin ophthalmic solution and 0.5% levofloxacin ophthalmic solution into aqueous humor after topical application. (medsci.org)
  • Lipids were extracted from aqueous humor by solid phase exaction, and analyzed via liquid chromatography tandem mass spectrometry (LC-MS/MS, Thermo Scientific) in negative-ion mode. (arvojournals.org)
  • Compared with the control group, the aqueous humor in wet AMD patients showed a significantly higher expression of CXCL10 (p=0.004), CCL14 (p=0.002), CXCL16 (p=0.013), CXCL7 (p=0.033), and CCL22 (p=0.037), while growth-related oncogene (GRO) was significantly decreased in the wet AMD patients (p=0.001). (nih.gov)
  • Polymerase chain reaction for the detection of Toxoplasma gondii within aqueous humor of experimentally-inoculated cats. (unboundmedicine.com)
  • TY - JOUR T1 - Polymerase chain reaction for the detection of Toxoplasma gondii within aqueous humor of experimentally-inoculated cats. (unboundmedicine.com)
  • The purpose of this study was to determine the temporal appearance of T. gondii in aqueous humor of cats orally inoculated with T. gondii using polymerase chain reaction (PCR) for the detection of the B1 gene. (unboundmedicine.com)
  • One-third of the proteins were identified by significantly lower spectral counts in the aqueous of the individual with moxifloxacin associated uveitis compared to the unaffected control. (umassmed.edu)
  • We have elicited a reliable Raman spectral signature for glucose in rabbit aqueous humor across mammalian physiological ranges in a rabbit model stressed by recent myocardial infarction. (sae.org)
  • Aqueous humor specimens were obtained within 21 days of diagnosis. (irjo.org)
  • While blebs are effective in removing the aqueous humor, bleb complications present the highest incidence of post-surgical complications due to irritation and infection. (google.com)
  • This volume present a basic consensus of how the aqueous humor is formed and exits through the trabecular meshwork and canal of Schlemm. (textbookx.com)
  • Therefore, the importance of furthering our understanding of how aqueous humor exits from the eye is of increasing interest. (omicsonline.org)