Appetite Stimulants
A prospective randomized study of megestrol acetate and ibuprofen in gastrointestinal cancer patients with weight loss. (1/70)
The use of megestrol acetate in the treatment of weight loss in gastrointestinal cancer patients has been disappointing. The aim of the present study was to compare the combination of megestrol acetate and placebo with megestrol acetate and ibuprofen in the treatment of weight loss in such patients. At baseline, 4-6 weeks and 12 weeks, patients underwent measurements of anthropometry, concentrations of albumin and C-reactive protein and assessment of appetite, performance status and quality of life using EuroQol-EQ-5D and EORTC QLQ-C30. Thirty-eight and 35 patients (median weight loss 18%) were randomized to megestrol acetate/placebo or megestrol acetate/ibuprofen, respectively, for 12 weeks. Forty-six (63%) of patients failed to complete the 12-week assessment. Of those evaluable at 12 weeks, there was a decrease in weight (median 2.8 kg) in the megestrol acetate/placebo group compared with an increase (median 2.3 kg) in the megestrol acetate/ibuprofen group (P<0.001). There was also an improvement in the EuroQol-EQ-5D quality of life scores of the latter group (P<0.05). The combination of megestrol acetate/ibuprofen appeared to reverse weight loss and appeared to improve quality of life in patients with advanced gastrointestinal cancer. Further trials of this novel regimen in weight-losing patients with hormone-insensitive cancers are warranted. (+info)Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist. (2/70)
1. We designed and synthesized several novel cyclic MSH analogues and tested their affinities for cells expressing the MC1, MC3, MC4 and MC5 receptors. 2. One of the substances HS028 (cyclic [AcCys11, dichloro-D-phenylalanine14, Cys18, Asp-NH2(22)]-beta-MSH11-22) showed high affinity (Ki of 0.95nM) and high (80 fold) MC4 receptor selectivity over the MC3 receptor. HS028 thus shows both higher affinity and higher selectivity for the MC4 receptor compared to the earlier first described MC4 receptor selective substance HS014. 3. HS028 antagonised a alpha-MSH induced increase in cyclic AMP production in transfected cells expressing the MC3 and MC4 receptors, whereas it seemed to be a partial agonist for the MC1 and MC5 receptors. 4. Chronic intracerebroventricularly (i.c.v.) administration of HS028 by osmotic minipumps significantly increased both food intake and body weight in a dose dependent manner without tachyphylaxis for a period of 7 days. 5. This is the first report demonstrating that an MC4 receptor antagonist can increase food intake and body weight during chronic administration providing further evidence that the MC4 receptor is an important mediator of long term weight homeostasis. (+info)Model for the regulation of energy balance and adiposity by the central nervous system. (3/70)
In 1995, we described a new model for adiposity regulation. Since then, data regarding the biology of body weight regulation has accumulated at a remarkable rate and has both modified and strengthened our understanding of this homeostatic system. In this review we integrate new information into a revised model for further understanding this important regulatory process. Our model of energy homeostasis proposes that long-term adiposity-related signals such as insulin and leptin influence the neuronal activity of central effector pathways that serve as controllers of energy balance. (+info)SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II. In vivo pharmacological characterization. (4/70)
SR146131 is a potent and selective agonist at cholecystokinin subtype 1 (CCK1) receptors in vitro. The present study evaluates the activity of the compound in vivo. SR146131 completely inhibited gastric and gallbladder emptying in mice (ED50 of 66 and 2.7 micrograms/kg p.o., respectively). SR146131 dose dependently reduced food intake in fasted rats (from 0.1 mg/kg p.o.), in nonfasted rats in which food intake had been highly stimulated by the administration of neuropeptide Y (1-36) (from 0.3 mg/kg p.o.), in fasted gerbils (from 0.1 mg/kg p.o.), and in marmosets maintained on a restricted diet (from 3 mg/kg p.o.). SR146131 (10 mg/kg p.o.) also increased the number of Fos-positive cells in the hypothalamic paraventricular nucleus of rats. Locomotor activity of mice was reduced by orally administered SR146131 (from 0.3 mg/kg p.o.). When administered intrastriatally, SR146131 elicited contralateral turning behavior in mice. Furthermore, orally administered SR146131 (0.3-10 mg/kg), also reduced the levels of cerebellar cyclic GMP. Finally, SR146131 (0.1 microgram/kg to 1 mg/kg, p.o.) significantly and dose dependently antagonized fluphenazine-induced mouth movements in rats. The CCK1 antagonist SR27897B prevented all the effects of SR146131. Conversely, SR146131 was unable to elicit any agonist or antagonist effects in a model of CCK2 receptor stimulation in vivo. SR146131 is a very potent and selective nonpeptide CCK1 agonist in vivo. SR146131 is more potent than any other CCK1 agonists reported to date. Because pharmacodynamic studies suggest that SR146131 should have a high absolute bioavailability, it may be a promising drug for the treatment of eating and motor disorders in humans. (+info)Neuropeptide Y restores appetite and alters concentrations of GH after central administration to endotoxic sheep. (5/70)
The objective of this study was to determine whether neuropeptide Y (NPY) and recombinant human interleukin-1 receptor antagonist (IL-1ra) would: first, increase food intake; secondly, decrease concentrations of GH; thirdly, reduce GHRH-induced release of GH; and fourthly, reduce changes to concentrations of IGF-I in plasma during experimental endotoxemia in sheep. Six treatments were given to six castrated male sheep in a 6x6 Latin square treatment order. Osmotic mini-pumps were implanted at 0 h and a jugular vein was cannulated. Each sheep was continuously infused with saline (0.9%) or lipopolysaccharide (LPS) (20 micrograms/kg per 24 h, s.c.) at 10 microliters/h for 72 h via the osmotic mini-pumps. Blood samples (3 ml) were collected at 15-min intervals from 24 to 33 h. At 26 h, one of three treatments (artificial cerebrospinal fluid, NPY or IL-1ra) was injected i.c.v. within 30 s (0.3 microgram/kg), then infused i.c.v. from 26 to 33 h (600 microliters/h) at 0.3 microgram/kg per h. GHRH was injected i.v. (0.075 microgram/kg) at 32 h after which blood samples were collected at 5, 10, 15, 30, 45 and 60 min. Feed intake was reduced up to 50% for 48 h in LPS-treated compared with non-LPS-treated sheep. NPY restored feed intake in LPS-treated sheep and induced hyperphagia in non-LPS-treated sheep from 24 to 48 h. In contrast, IL-1ra did not affect appetite. Injection of NPY increased concentrations of GH from 26 to 27 h, while IL-1ra had no effect. Infusion of NPY suppressed GHRH-induced release of GH. However, no treatment altered pulse secretion parameters of GH. Concentrations of IGF-I were 20% higher at 72 h in LPS-treated sheep given NPY than in sheep treated with LPS alone, and this may reflect increased appetite from 24 to 48 h. We concluded that reduced appetite during endotoxemia is due to down-regulation of an NPY-mediated mechanism. Furthermore, NPY stimulates release of GH in healthy sheep, does not reduce pulse secretion parameters of GH, but does suppress GHRH-induced release of GH in endotoxic sheep. Therefore, NPY may be an important neurotransmitter linking appetite with regulation of GH during endotoxemic and healthy states in sheep. (+info)Effects of delta 9-tetrahydrocannabinol and diazepam on feeding behavior in mice. (6/70)
The present study examined effects of diazepam (DZP) alone or in combination with delta 9-tetrahydrocannabinol (THC) on feeding behavior as well as body weight in male ddY strain mice at 5 weeks of age. Because we saw no hyperphagic effect of DZP with or without THC in mice, we explored the hyperphagia elicitable by DZP. THC [2 (THC2) or 4 (THC4) mg/kg/day s.c.] was given daily for 7 days. For the last day the mice were starved and injected i.p. with DZP (2 mg/kg) 10 min prior to a food or maze test. Controls received vehicle injections. Feeding behavior was measured after giving food for 2 hr. THC4 significantly reduced body weight gain. DZP, with or without THC, induced hyperphagia. THC4 alone also induced hyperphagia that was not significantly affected by DZP. Time taken to find food was extended by DZP and further with THC. Both DZP and THC can therefore interact on food ingestion but synergize on food seeking in mice through different mechanisms. (+info)Geriatric cachexia: the role of cytokines. (7/70)
Weight loss in elderly patients is a common clinical problem. Wasting and cachexia are associated with severe physiologic, psychologic, and immunologic consequences, regardless of the underlying causes. Cachexia has been associated with infections, decubitus ulcers, and even death. Multivariate analyses of risk and prognostic factors in community-acquired pneumonia in the elderly have found that age by itself is not a significant factor related to prognosis. Among the significant risk factors, only nutritional status is amenable to medical intervention. Cachexia in the elderly may have profound consequences: medical, cognitive, and psychiatric disorders may diminish self-reliance in activities of daily living, thus reducing quality of life and increasing the frequency of secondary procedures, hospitalizations, and the need for skilled care. Cachexia is associated with higher-than-normal concentrations of tumor necrosis factor alpha (TNF-alpha), interleukin (IL) 1, IL-6, serotonin, and interferon gamma. The role of these proinflammatory cytokines has been established in the cachexia seen in cancer and AIDS patients. Reduction in the concentrations of these cytokines is associated with weight gain. Drugs that promote appetite stimulation and weight gain, such as progestational agents, cyproheptadines, pentoxifylline, and thalidomide may work by down-regulating these proinflammatory cytokines. An understanding of the relation between cachexia and negative regulatory cytokines may point to effective treatment of geriatric cachexia as well. (+info)Evaluation and treatment of weight loss in adults with HIV disease. (8/70)
Weight loss late in the course of human immunodeficiency virus (HIV) disease is common and often multifactorial. Increased energy expenditure in response to opportunistic disease, as well as to HIV infection itself, can lead to protein-calorie malnutrition similar to that observed in starvation. Weight loss of as little as 5 percent in patients with HIV infection is associated with an increased risk of disease progression. Loss of body cell mass carries a particularly poor prognosis, and aggressive measures should be taken to stop such depletion. Patients exhibiting unexpected weight loss should be carefully examined to exclude decreased food intake, malabsorption, occult infection or neoplasm as the etiology of the weight loss. Early aggressive treatment of HIV disease and underlying opportunistic pathology, along with adequate pharmacologic, hormonal, nutritional and physical therapy, can often restore normal weight and body composition. (+info)VetVine - Forum - Appetite Stimulants
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Dynorphin
... has been implicated as an appetite stimulant. A number of studies in rats have shown that increasing the dynorphin ... They found that endogenous opioids, such as dynorphin, stimulate appetite and decrease energy expenditure. Taken together, the ... Morley LE (1995). "The Role of Peptides in Appetite Regulation across Species". American Zoologist. 35 (6): 437-445. doi: ... Dynorphins are important in maintaining homeostasis through appetite control and circadian rhythms. Przewlocki et al. found ...
ATC code A15
... Appetite stimulants is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a ... Appetite stimulants "ATC (Anatomical Therapeutic Chemical Classification System) - Synopsis". National Institutes of Health. ...
Gastroparesis
This is due to its antiemetic and appetite stimulant properties. Mirtazapine acts on the same serotonin receptor (5-HT3) as ... General malnutrition due to the symptoms of the disease (which frequently include vomiting and reduced appetite) as well as the ... Heartburn Lack of appetite Morning nausea Muscle weakness Night sweats Palpitations Spasms of the stomach wall Constipation or ...
Hunger (physiology)
Ghrelin, a hormone produced by the stomach, is an appetite stimulant. Two psychological processes appear to be involved in ... For example, ghrelin stimulates appetite, whereas cholecystokinin and glucagon-like peptide-1 (GLP-1) suppress appetite. The ... The regulation of appetite (the appestat) has been the subject of much research; breakthroughs included the discovery, in 1994 ... The desire to eat food, or appetite, is another sensation experienced with regards to eating. The term hunger is also the most ...
Differential diagnoses of anorexia nervosa
Using substituted amphetamines (stimulants that can reduce appetite) to reduce appetite. Skin turning yellow Some of the ... Dukarm, C. P. (2005). "Bulimia Nervosa and Attention Deficit Hyperactivity Disorder: A Possible Role for Stimulant Medication ...
Cachexia
Appetite stimulant medications are used to treat cachexia to increase food intake, but are not effective in stopping muscle ... Appetite stimulants include glucocorticoids, cannabinoids, or progestins such as megestrol acetate. Anti-emetics such as 5-HT3 ... The increased metabolic rate and appetite suppression common in cachexia can compound muscle loss. Studies using a calorie- ... appetite loss, and laboratory changes to categorize patients into non-cachexia, pre-cachexia, cachexia, and refractory cachexia ...
Underweight
Homnick, Douglas N. (2005). "Long-term trial of cyproheptadine as an appetite stimulant in cystic fibrosis". Pediatric ... Exercise can also help stimulate the appetite of a person who is not inclined to eat. Certain drugs may increase appetite ... In states where it is approved, medicinal cannabis may be prescribed for severe appetite loss, such as that caused by cancer, ... Other drugs or supplements which may increase appetite include antihistamines (such as diphenhydramine, promethazine or ...
Cyproheptadine
... is used in cats as an appetite stimulant: 1371 and as an adjunct in the treatment of asthma. Possible adverse ... Ciproheptadina, estimulante del apetito (Cyproheptadine, appetite stimulant) "Bioplex NF". Archived from the original on 2018- ... Appetite stimulants, Dibenzocycloheptenes, Dopamine antagonists, Local anesthetics, Muscarinic antagonists, Piperidines, 5-HT2 ... One of the effects of the drug is increased appetite and weight gain, which has led to its use (off-label in the USA) for this ...
Native American ethnobotany
They also used it as a stimulant, an appetite enhancer and a charm. It was also used as an admixture to strengthen other herbal ...
Anorectic
By contrast, an appetite stimulant is referred to as orexigenic. The term is (from the Greek ἀν- (an-) = "without" and ὄρεξις ( ... or appetite suppressant. Used on a short-term basis clinically to treat obesity, some appetite suppressants are also available ... Several appetite suppressants are based on a mix of natural ingredients, mostly using green tea as its basis, in combination ... Most common natural appetite suppressants are based on Hoodia, a genus of 13 species in the flowering plant family Apocynaceae ...
Steroidal antiandrogen
Mostly used as an appetite stimulant in patients with cachexia. Oxendolone (Prostetin, Roxenone): A combined AR antagonist and ...
Cotoneaster nummularius
Cotoneaster nummularis is used in folk medicine; decoctions made from the fruits is taken orally as an appetite stimulant, ...
Mefenorex
... (Rondimen, Pondinil, Anexate) is a stimulant drug which was used as an appetite suppressant. It is an amphetamine ... Beyer G, Huth K, Müller GM, Niemöller H, Raisp I, Vorberg G (February 1980). "[The treatment of obesity with the appetite ... Mefenorex produces amphetamine as a metabolite, and has been withdrawn in many countries despite having only mild stimulant ... Vincendeau MJ (1970). "[A new regulator of appetite: mefenorex]". Bordeaux Medical (in French). 3 (7): 1951-3. PMID 5455004. ...
Poison dart frog
Secretions from dendrobatids are also showing promise as muscle relaxants, heart stimulants and appetite suppressants. The most ...
Catharanthus trichophyllus
It is used as a stimulant, an aphrodisiac, and an appetite suppressant. The plant is a congeneric of the Madagascar periwinkle ...
Isomer
It is used as an appetite-reducing medication and has mild or no stimulant properties. However, an alternate atomic arrangement ... Another example of this occurs in the phenethylamine-based stimulant drugs. Phentermine is a non-chiral compound with a weaker ... gives dextromethamphetamine, which is a stronger stimulant than amphetamine. In medicinal chemistry and biochemistry, ...
Anise
In Turkish folk medicine, its seeds have been used as an appetite stimulant, tranquilizer or diuretic. Anise essential oil can ...
Eating disorder
... pharmacists sell appetite stimulants to women who desire to, as Ghanaians stated, "grow fat". Girls are told that if they wish ... it has an inhibitory effect on appetite by inducing a feeling of satiety. Ghrelin is an appetite inducing hormone produced in ... Additionally, traditional Fijian values would encourage a robust appetite and a widespread vigilance for and social response to ... Prader-Willi syndrome, a genetic disorder associated with insatiable appetite and morbid obesity. Pregorexia, which is ...
Healthy Skepticism
These included the promotion of appetite stimulants, tonics and anabolic steroids to parents of malnourished children. MaLAM ...
Megestrol acetate
MGA is frequently used as an appetite stimulant to promote weight gain. The direct mechanism of appetite enhancement is unclear ... MGA is used mainly as an appetite stimulant to promote weight gain in a variety of situations. When given at very high dosages ... The mechanism of action of the appetite stimulant effects of MGA is unknown. MGA was discovered in 1959 and was introduced for ... This led to potential interest in MGA as an appetite stimulant, and in 1986, a paper was published proposing the study and ...
Cuphea
There is also reason to believe the plant could be effective as an appetite stimulant.[citation needed] Cuphea aspera Chapman ...
Mankind Pharma
Also it acquired Longifene-an appetite stimulant for children in January 2010 which was earlier a brand of UCB. In 2019, ...
Caregiver
One alternative to using appetite stimulants is to provide social support, as many people are more comfortable eating when ... Caregivers are recommended to help people find alternatives to using appetite stimulants or food supplements high in food ... feed the person what they enjoy eating despite the health consequences if that seems preferable to avoiding appetite stimulants ...
Asarum canadense
In addition, they also used it as a stimulant or appetite enhancer, and as a charm. It was also used as an admixture to ...
Mazindol
... (brand names Mazanor, Sanorex) is a stimulant drug which is used as an appetite suppressant. It was developed by ... Sympathomimetic anoretics (appetite suppressants) are used in the short-term treatment of obesity. Their appetite-reducing ... Like other sympathomimetic appetite suppressants, mazindol is thought to act as a reuptake inhibitor of norepinephrine. In ... It stimulates the central nervous system, which increases heart rate and blood pressure, and decreases appetite. ...
Solanum nigrum
The fruits are used as a tonic, laxative, appetite stimulant, and for treating asthma and "excessive thirst". Traditionally the ...
Breast milk
They may act as an appetite stimulant, but they also regulate appetite so infants don't eat too much. That may be why formula- ... Fride E, Bregman T, Kirkham TC (April 2005). "Endocannabinoids and food intake: newborn suckling and appetite regulation in ...
Agouti-related peptide
One is an appetite stimulant, ghrelin which makes AgRP neurons more excitable through interactions with specialized ghrelin ... The appetite-stimulating effects of AgRP are inhibited by the hormone leptin and activated by the hormone ghrelin. Adipocytes ... It is one of the most potent and long-lasting of appetite stimulators. In humans, the agouti-related peptide is encoded by the ... Ghrelin has receptors on NPY/AgRP neurons that stimulate the secretion of NPY and AgRP to increase appetite. AgRP is stored in ...
Diazepam
... is used as a short-term sedative and anxiolytic for cats and dogs, sometimes used as an appetite stimulant. It can ... Sometimes, it is used by stimulant users to "come down" and sleep and to help control the urge to binge. These users often ... "Drugs Affecting Appetite (Monogastric)". The Merck Veterinary Manual. Archived from the original on 28 October 2012. Retrieved ... with the exception of hallucinogens or some stimulants, where it is occasionally used as a treatment for overdose) History of ...
Bitter orange
... is also employed in herbal medicine as a stimulant and appetite suppressant, due to its active ingredient, ... Following bans on the herbal stimulant ephedra in the U.S., Canada, and elsewhere, bitter orange has been substituted into " ... has been marketed as dietary supplement purported to act as a weight-loss aid and appetite suppressant. Bitter orange contains ... Herbal and fungal stimulants, Medicinal plants, Oranges (fruit), Plants described in 1753, Citrus hybrids). ...
Cannabinoid
Dronabinol (Marinol), is Δ9-tetrahydrocannabinol (THC), used as an appetite stimulant, anti-emetic, and analgesic ... Dronabinol (brand name Marinol) is a THC drug used to treat poor appetite, nausea, and sleep apnea.[49] It is approved by the ... Fride E, Bregman T, Kirkham TC (April 2005). "Endocannabinoids and food intake: newborn suckling and appetite regulation in ...
Crack cocaine
Effects of crack cocaine include euphoria,[12] supreme confidence,[13] loss of appetite,[12] insomnia,[12] alertness,[12] ... Stimulant drug abuse (particularly amphetamine and cocaine) can lead to delusional parasitosis (aka Ekbom's Syndrome: a ... The use of another highly addictive stimulant drug, crystal meth, ballooned between 1994 and 2004.[3][4] ...
History of coffee
قها, "to lack hunger") in reference to the drink's reputation as an appetite suppressant.[4][6] The word qahwah is sometimes ... evidence has ever been found indicating where in Africa coffee grew or who among the natives might have used it as a stimulant ...
Mountaineering
Common symptoms of altitude sickness include severe headache, sleep problems, nausea, lack of appetite, lethargy and body ache ... based on the stimulant methamphetamine used by soldiers during World War II), padutin and tea from coca leaves. K2 (8,611 m), ...
Lisdexamfetamine
Recent studies have demonstrated that stimulants, along with the non-stimulants atomoxetine and extended-release guanfacine, ... Common side effects of lisdexamfetamine include loss of appetite, anxiety, diarrhea, trouble sleeping, irritability, and nausea ... stimulant and nonstimulant medications and misuse of prescription stimulants". Psychology Research and Behavior Management. 7: ... of those who use these stimulants see improvements in ADHD symptoms.[32] Children with ADHD who use stimulant medications ...
Pemoline
... is described as a lower-efficacy/milder stimulant than classical stimulants like amphetamines and methylphenidate and ... Side effects of pemoline include insomnia, decreased appetite, abdominal pain, irritability, and headaches. It has minimal ... in contrast to many other stimulants. Pemoline was synthesized in 1913 but was not discovered to be a stimulant until the 1930s ... Pemoline is a schedule IV controlled substance in the United States due to its relation to other stimulants and a potential for ...
Effects of cannabis
The feeling of increased appetite following the use of cannabis has been documented for hundreds of years, and is known ... While psychoactive drugs are typically categorized as stimulants, depressants, or hallucinogens, cannabis exhibits a mix of all ... Fride E, Bregman T, Kirkham TC (April 2005). "Endocannabinoids and food intake: newborn suckling and appetite regulation in ... or appetite for breast milk" and recent research has identified the endogenous cannabinoid system to be the first neural system ...
Heat intolerance
Other causes include: Amphetamines along with other types of stimulant medications, such as appetite suppressants ...
List of Kamen Rider W characters
Using bio-stimulants to ensure he ages properly, he proves to be a superior fighter, but he and Maria are forced to go rogue ... operates independently to commit a series of brutal murders to satisfy his appetite until Kamen Rider W defeats him. Sabu is ...
Phenethylamine
... appetite suppressants (e.g. phentermine), nasal decongestants and bronchodilators (e.g., pseudoephedrine), antidepressants (e.g ... a defining feature that underlies the abuse liability of amphetamine and other psychomotor stimulants. β-PEA was also as ... which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission ... stimulants, psychedelics, anorectics, bronchodilators, decongestants, and/or antidepressants, among others. Phenethylamine is ...
List of designer drugs
Harm S (11 April 1967). "US Patent 3313687 - Appetite-suppressing and weight reducing composition". "4F-IVP". Cayman Chemical. ... Amphetamines are a chemical class of stimulants, entactogens, hallucinogens, and other drugs. They feature a phenethylamine ... and/or stimulants, as well as entheogens. 5-Methoxymethylone, βk-MMDMA, "2-A1MP" 5-Methylethylone, 5-Me-βk-MDEA, 5-ME 5-Methyl- ... 3-Fluoroethamphetamine Stimulants produce a variety of different kinds of effects by enhancing the activity of the central and ...
Tesofensine
This could also help account for why Tesofensine is not reliably self-administered by human stimulant abusers since it has been ... Tesofensine primarily acts as an appetite suppressant, but possibly also acts by increasing resting energy expenditure. Phase ... "Subjective and objective effects of the novel triple reuptake inhibitor tesofensine in recreational stimulant users". Clinical ...
Atypical antipsychotic
McKim W (2007). Psychomotor Stimulants in Drugs and Behavior: An Introduction to Behavioral Pharmacology. Upper Saddle River, ... Symptoms of withdrawal commonly include nausea, vomiting, and loss of appetite. Other symptoms may include restlessness, ...
Ioflupane (123I)
Common side effects of ioflupane (123I) are headache, vertigo, increased appetite and formication. Less than 1% of patients ... Stimulants, Organofluorides, Iodoarenes, Extrapyramidal and movement disorders, Parkinson's disease). ...
Doping in tennis
The substance is widely prescribed to sufferers of obesity and diabetes with the main effect of the drug being an appetite ... The drug is a widely used stimulant that affects respiratory function through the increase in blood flow and oxygen intake ... In 2013, Barbora Záhlavová-Strýcová tested positive to the banned stimulant, sibutramine while competing at the 2013 Luxembourg ...
Nabilone
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