Appetite depressants. Medical search

Agents that are used to suppress appetite.

Natural recurring desire for food. Alterations may be induced by APPETITE DEPRESSANTS or APPETITE STIMULANTS.

Physiologic mechanisms which regulate or control the appetite and food intake.

Agents that are used to stimulate appetite. These drugs are frequently used to treat anorexia associated with cancer and AIDS.

A low molecular weight peptide of about 800-1000 having a negative inotropic effect. It is released into the circulation during experimental hemorrhagic pancreatitis, severe ischemia, and postoligemic shock.

The decrease in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.

Full gratification of a need or desire followed by a state of relative insensitivity to that particular need or desire.

The desire for FOOD generated by a sensation arising from the lack of food in the STOMACH.

Behavioral response associated with the achieving of gratification.

A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.

A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).

The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

The consumption of edible substances.

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)

A 36-amino acid peptide produced by the L cells of the distal small intestine and colon. Peptide YY inhibits gastric and pancreatic secretion.

A class of chemicals derived from barbituric acid or thiobarbituric acid. Many of these are GABA MODULATORS used as HYPNOTICS AND SEDATIVES, as ANESTHETICS, or as ANTICONVULSANTS.

Behavioral responses or sequences associated with eating including modes of feeding, rhythmic patterns of eating, and time intervals.

The consumption of liquids.

Venoms from animals of the order Scorpionida of the class Arachnida. They contain neuro- and hemotoxins, enzymes, and various other factors that may release acetylcholine and catecholamines from nerve endings. Of the several protein toxins that have been characterized, most are immunogenic.

Total number of calories taken in daily whether ingested or by parenteral routes.

A drive stemming from a physiological need for WATER.

A dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for MIGRAINE DISORDERS therapy.

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.

An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.

Hormones synthesized from amino acids. They are distinguished from INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS in that their actions are systemic.

A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)

A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.

Agents that are capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.

A portion of the food eaten for the day, usually at regular occasions during the day.

A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.

Therapeutic introduction of ions of soluble salts into tissues by means of electric current. In medical literature it is commonly used to indicate the process of increasing the penetration of drugs into surface tissues by the application of electric current. It has nothing to do with ION EXCHANGE; AIR IONIZATION nor PHONOPHORESIS, none of which requires current.

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)

The relationship between the dose of an administered drug and the response of the organism to the drug.

A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)

Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.

A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.

HORMONES secreted by the gastrointestinal mucosa that affect the timing or the quality of secretion of digestive enzymes, and regulate the motor activity of the digestive system organs.

The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)

An MAO inhibitor that is used as an antidepressive agent.

Arthropods of the order Scorpiones, of which 1500 to 2000 species have been described. The most common live in tropical or subtropical areas. They are nocturnal and feed principally on insects and other arthropods. They are large arachnids but do not attack man spontaneously. They have a venomous sting. Their medical significance varies considerably and is dependent on their habits and venom potency rather than on their size. At most, the sting is equivalent to that of a hornet but certain species possess a highly toxic venom potentially fatal to humans. (From Dorland, 27th ed; Smith, Insects and Other Arthropods of Medical Importance, 1973, p417; Barnes, Invertebrate Zoology, 5th ed, p503)

A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.

Derivatives of BUTYRIC ACID that contain one or more amino groups attached to the aliphatic structure. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the aminobutryrate structure.

A peptide, of about 33 amino acids, secreted by the upper INTESTINAL MUCOSA and also found in the central nervous system. It causes gallbladder contraction, release of pancreatic exocrine (or digestive) enzymes, and affects other gastrointestinal functions. Cholecystokinin may be the mediator of satiety.

The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).

A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity.

Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.

Saturated derivatives of the steroid pregnane. The 5-beta series includes PROGESTERONE and related hormones; the 5-alpha series includes forms generally excreted in the urine.

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration.

The chemical reactions involved in the production and utilization of various forms of energy in cells.

The time frame after a meal or FOOD INTAKE.

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.

The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.

The action of a drug that may affect the activity, metabolism, or toxicity of another drug.

The selection of one food over another.

A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.

Elements of limited time intervals, contributing to particular results or situations.

Use of electric potential or currents to elicit biological responses.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

General ill health, malnutrition, and weight loss, usually associated with chronic disease.

Thermogenic effects of sibutramine and its metabolites. (1/354)

1. The thermogenic activity of the serotonin and noradrenaline reuptake inhibitor sibutramine (BTS 54524; Reductil) was investigated by measuring oxygen consumption (VO2) in rats treated with sibutramine or its two pharmacologically-active metabolites. 2. Sibutramine caused a dose-dependent rise in VO2, with a dose of 10 mg kg(-1) of sibutramine or its metabolites producing increases of up to 30% that were sustained for at least 6 h, and accompanied by significant increases (0.5-1.0 degrees C) in body temperature. 3. Based on the accumulation in vivo of radiolabelled 2-deoxy-[3H]-glucose, sibutramine had little or no effect on glucose utilization in most tissues, but caused an 18 fold increase in brown adipose tissue (BAT). 4. Combined high, non-selective doses (20 mg kg(-1)) of the beta-adrenoceptor antagonists, atenolol and ICI 118551, inhibited completely the VO2 response to sibutramine, but the response was unaffected by low, beta1-adrenoceptor-selective (atenolol) or beta2-adrenoceptor-selective (ICI 118551) doses (1 mg kg(-1)). 5. The ganglionic blocking agent, chlorisondamine (15 mg kg(-1)), inhibited completely the VO2 response to the metabolites of sibutramine, but had no effect on the thermogenic response to the beta3-adrenoceptor-selective agonist BRL 35135. 6. Similar thermogenic responses were produced by simultaneous injection of nisoxetine and fluoxetine at doses (30 mg kg(-1)) that had no effect on VO2 when injected individually. 7. It is concluded that stimulation of thermogenesis by sibutramine requires central reuptake inhibition of both serotonin and noradrenaline, resulting in increased efferent sympathetic activation of BAT thermogenesis via beta3-adrenoceptor, and that this contributes to the compound's activity as an anti-obesity agent. (+info)

Use of dexfenfluramine, fenfluramine and phentermine and the risk of stroke. (2/354)

AIMS: To estimate the incidence of newly diagnosed idiopathic stroke among users of fenfluramine, dexfenfluramine and phentermine compared to obese nonusers. METHODS: We conducted a cohort study with nested case-control analysis utilizing data from the General Practice Research Database in the UK. Eight thousand four hundred and twenty-three subjects aged 69 years or less at the start of follow-up were exposed to at least one of the three study drugs and 17 225 similarly obese subjects were not exposed to any of the study drugs. RESULTS: We identified 45 incident cases of idiopathic CVA in this cohort of subjects. The incidence of CVA among all current users of a diet drug was 1.3/1000 person-years (95% CI 0.5, 3.5). The incidence for current fenfluramine users (n=2) was 2.6/1000 person-years (95% CI 0.7, 9.6), for current dexfenfluramine users (n=1) 1.1/1000 person-years (95% CI 0.3, 3.8), and for current phentermine users 0/1000 person-years (95% CI 0.0, 12.9). The incidence in obese nonusers was 0.6/1000 person-years (95% CI 0.4, 0. 9). The adjusted matched odds ratio (OR) for thrombotic stroke from the case-control analysis comparing current use of a diet drug to nonuse was 2.4 (95% CI 0.6, 9.1). There was only one exposed subject among seven who had haemorrhagic stroke. CONCLUSIONS: The incidence of CVA in generally young obese subjects during use of fenfluramine, dexfenfluramine or phentermine is low. Although we found an OR of 2. 4 comparing users of any of the anorexiants with nonusers, this is based on only three exposed cases and the confidence limits are wide. We conclude that our study does not support a substantial increased risk of stroke attributable to the use of fenfluramine, dexfenfluramine or phentermine. (+info)

Amphetamine and fenproporex levels following multidose administration of fenproporex. (3/354)

Drugs that are metabolized to amphetamine or methamphetamine are potentially of significant concern in the interpretation of positive drug-testing results for amphetamines. A number of different drugs have been reported to produce amphetamine in the urine of users. One of these compounds, fenproporex, has been shown to be metabolized to amphetamine, and previous reports indicated the parent compound could be detected at low levels for up to 48 h. Administration of fenproporex for seven days (one 10-mg dose per day) to five healthy volunteers resulted in amphetamine being detected in the urine of all subjects. Peak concentrations of amphetamine ranged from approximately 2850 to 4150 ng/mL. Amphetamine could be detected (> or = 5 ng/mL) in the urine for up to nearly 170 h after the last dose. Analysis of the metabolically produced amphetamine showed the presence of both enantiomers, which can be helpful in the differentiation of some illicit amphetamine use from the use of this precursor drug. In addition, evaluation of the enantiomeric composition of the metabolite (amphetamine) can be a valuable tool in the interpretation of time since last dose. More significantly, all samples that contained amphetamine at a concentration of > or = 500 ng/mL were shown to also contain detectable amounts of the parent compound. (+info)

Pharmacologic induction of weight loss to treat type 2 diabetes. (4/354)

OBJECTIVE: Most individuals with type 2 diabetes are overweight, and weight loss for them is an important therapeutic objective. However, usual weight-loss strategies have generally not produced sustained weight loss. Pharmacologic agents to assist weight loss might be useful, but no long-term data on their effectiveness and safety in patients with type 2 diabetes are available. We therefore initiated a 2-year placebo-controlled trial of the weight-loss medications fenfluramine and phentermine in type 2 diabetic subjects. RESEARCH DESIGN AND METHODS: A total of 44 overweight (> 120% ideal body weight) subjects with type 2 diabetes were enrolled in a randomized, placebo-controlled, double-blind trial of fenfluramine and phentermine. All subjects received intensive nutrition counseling, an exercise prescription, and instruction in behavior modification. Subjects were randomly assigned to 20 mg fenfluramine three times a day and 37.5 mg phentermine daily (n = 23) or dual placebos (n = 21). Diabetes medications were adjusted as necessary to achieve glycemic goals. Changes in weight, glycemia, lipemia, and blood pressure were assessed every 2 months, as were adverse events. In September 1997, when fenfluramine was withdrawn from the U.S. market, fenfluramine was stopped in all subjects. Thus the length of drug treatment varied, but 16 subjects (8 in each group) reached 12 months of treatment. Only data obtained before the withdrawal of fenfluramine are included in this report. RESULTS: A study termination, diabetes medications had been reduced in 1 subject in the placebo group (5%) and 11 subjects in the drug treatment group (52%) (P = 0.005). Drug treatment resulted in significant reductions in body weight, BMI, and HbA1c at all time points through 6 months. Changes in weight at 6 months were -2.7 +/- 1.4 kg (mean +/- SEM) with placebo treatment and -9.6 +/- 1.5 kg with drug treatment (P = 0.003). Even though more subjects in the drug treatment group required reductions in diabetes medications, at 6 months, changes in HbA1c were -0.3 +/- 0.2% with placebo treatment and -1.6 +/- 0.3% with drug treatment (P = 0.002). Fasting plasma glucose and triglycerides were significantly reduced at some time points with drug treatment. No serious adverse events attributable to study medications were observed. CONCLUSIONS: Premature study termination decreased the power of our study at later time points. However, our data suggest that weight loss medications are an effective treatment for type 2 diabetes during active weight loss. Whether the benefit persists after weight loss has stopped remains to be determined. (+info)

Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. (5/354)

OBJECTIVE: The gut hormone glucagon-like peptide 1 (GLP-1) has insulinotropic and anorectic effects during intravenous infusion and has been proposed as a new treatment for type 2 diabetes and obesity. The effect of a single subcutaneous injection is brief because of rapid degradation. We therefore sought to evaluate the effect of infusion of GLP-1 for 48 h in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: We infused GLP-1 (2.4 pmol.kg-1.min-1) or saline subcutaneously for 48 h in randomized order in six patients with type 2 diabetes to evaluate the effect on appetite during fixed energy intake and on plasma glucose, insulin, glucagon, postprandial lipidemia, blood pressure, heart rate, and basal metabolic rate. RESULTS: The infusion resulted in elevations of the plasma concentrations of intact GLP-1 similar to those observed after intravenous infusion of 1.2 pmol.kg-1.min-1, previously shown to lower blood glucose effectively in type 2 diabetic patients. Fasting plasma glucose (day 2) decreased from 14.1 +/- 0.9 (saline) to 12.2 +/- 0.7 mmol/l (GLP-1), P = 0.009, and 24-h mean plasma glucose decreased from 15.4 +/- 1.0 to 13.0 +/- 1.0 mmol/l, P = 0.0009. Fasting and total area under the curve for insulin and C-peptide levels were significantly higher during the GLP-1 administration, whereas glucagon levels were unchanged. Neither triglycerides nor free fatty acids were affected. GLP-1 administration decreased hunger and prospective food intake and increased satiety, whereas fullness was unaffected. No side effects during GLP-1 infusion were recorded except for a brief cutaneous reaction. Basal metabolic rate and heart rate did not change significantly during GLP-1 administration. Both systolic and diastolic blood pressure tended to be lower during the GLP-1 infusion. CONCLUSIONS: We conclude that 48-h continuous subcutaneous infusion of GLP-1 in type 2 diabetic patients 1) lowers fasting as well as meal-related plasma glucose, 2) reduces appetite, 3) has no gastrointestinal side effects, and 4) has no negative effect on blood pressure. (+info)

Studies on the role of serotonin receptor subtypes in the effect of sibutramine in various feeding paradigms in rats. (6/354)

The effect of the 5-hydroxytryptamine (5-HT) and noradrenaline (NA) reuptake inhibitor sibutramine was studied in food deprived, neuropeptide Y (NPY)- or muscimol-injected rats. Sibutramine dose-dependently reduced feeding caused by food-deprivation (ED50 = 5.1+/-0.8 mg kg(-1)) or by NPY injection into the paraventricular nucleus of the hypothalamus (ED50 = 6.0+/-0.5 mg kg(-1)). The increase in food intake caused by muscimol injected into the dorsal raphe was not modified by sibutramine (1-10 mg kg(-1)). The hypophagic effect of 5.1 mg kg(-1) sibutramine in food-deprived rats was studied in rats pretreated with different serotonin receptor antagonists. Metergoline (non-selective, 0.3 and 1.0 mg kg(-1)), ritanserin (5-HT2A/2C, 0.5 and 1.0 mg kg(-1)) and GR127935 (5-HT1B/1D), 0.5 and 1.0 mg kg(-1)) did not modify the hypophagic effect of sibutramine, while SB206553 (5-HT2B/2C, 5 and 10 mg kg(-1)) slightly but significantly reduced it (Fint(2.53) = 3.4; P<0.05). The reduction in food intake caused by 6.0 mg kg(-1) sibutramine in NPY-injected rats was not modified by GR127935 (1.0 mg kg(-1)). The results suggest that, with the possible exception of a partial involvement of 5-HT2B/2C receptors in sibutramine's hypophagia in food-deprived rats, 5-HT1 and 5-HT2 receptor subtypes do not play an important role in the hypophagic effect of sibutramine, at least in the first 2 h after injection. (+info)

Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. (7/354)

BACKGROUND: Coadministration of phentermine and fenfluramine (phen/fen) effectively treats obesity and possibly addictive disorders. The association of fenfluramine and certain other anorexic agents with serious side effects, such as cardiac valvulopathy and primary pulmonary hypertension (PPH), limits the clinical utility of these drugs. Development of new medications that produce neurochemical effects like phen/fen without causing unwanted side effects would be a significant therapeutic breakthrough. METHODS AND RESULTS: We tested the hypothesis that fenfluramine (and other anorexic agents) might increase the risk of PPH through interactions with serotonin (5-HT) transporters. Because 5-HT transporter proteins in the lung and brain are identical, we examined, in rat brain, the effects of selected drugs on 5-HT efflux in vivo and monoamine transporters in vitro as a generalized index of transporter function. Our data show that drugs known or suspected to increase the risk of PPH (eg, aminorex, fenfluramine, and chlorphentermine) are 5-HT transporter substrates, whereas drugs that have not been shown to increase the risk of PPH are less potent in this regard. CONCLUSIONS: We speculate that medications that are 5-HT transporter substrates get translocated into pulmonary cells where, depending on the degree of drug retention, their intrinsic drug toxicity, and individual susceptibility, PPH could develop as a response to high levels of these drugs or metabolites. Emerging evidence suggests that it is possible to develop transporter substrates devoid of adverse side effects. Such medications could have therapeutic application in the management of obesity, drug dependence, depression, and other disorders. (+info)

The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci. (8/354)

The ability of three extensively used anorectic drugs, namely fenfluramine (FN), fluoxetine (FX) and amphetamine (AM), to alter the development of aflatoxin B(1) (AFB(1))-induced gamma-glutamyl-positive (GGT(+)) preneoplastic liver foci was investigated in 135 male weanling F344 rats. Following AFB(1) administration, 15 rats were killed, while the rest were divided into four groups and fed diets containing either FN, FX, AM or control diet, with half of the animals in each group subsequently being killed at 4 weeks and half at 10 weeks. All three anorectic drugs as expected suppressed initial food intake, growth rate, body weight gain and food efficiency. They also tended to suppress body fat mass and to decrease plasma levels of T(3) and T(4). FN significantly (P < 0.05) increased GGT(+) foci number/cm(2) and number/cm(3), while FX significantly increased GGT(+) foci number/cm(2) and the volume fraction of foci. Histopathological staining also revealed that FN- and FX-treated animals had more serious morphological alterations in their liver tissue. In contrast, foci development was, if anything, suppressed by AM feeding. These results indicate that serotoninergic drugs (FN and FX), as opposed to dopaminergic drugs (AM), may have tumor promoter activity, at least for liver tissue. (+info)

Opitz K, Kemper F, Loeser A (March 1965). "[Comparative study of the anorexigenic potency of some appetite depressants]". ...

https://en.wikipedia.org/wiki/Pentorex

Therapeutic experiences with the appetite depressant eventin]. Wiener Medizinische Wochenschrift (in German). 108 (14): 304-6. ...

https://en.wikipedia.org/wiki/Levopropylhexedrine

... appetite depressants MeSH D27.505.954.427.153 - antitussive agents MeSH D27.505.954.427.210 - central nervous system ... appetite stimulants MeSH D27.505.954.427.220.224 - convulsants MeSH D27.505.954.427.270 - emetics MeSH D27.505.954.427.300 - ... central nervous system depressants MeSH D27.505.696.277.100 - anesthetics MeSH D27.505.696.277.100.017 - anesthetics, combined ... appetite stimulants MeSH D27.505.696.282.224 - convulsants MeSH D27.505.696.329 - emetics MeSH D27.505.696.353 - endocrine ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D27)

Topiramate The following are listed as appetite depressants by MeSH, an index of medical journal articles and books. Benfluorex ... or appetite suppressant. Used on a short-term basis clinically to treat obesity, some appetite suppressants are also available ... By contrast, an appetite stimulant is referred to as orexigenic. The term is (from the Greek ἀν- (an-) = "without" and ὄρεξις ( ... Several appetite suppressants are based on a mix of natural ingredients, mostly using green tea as its basis, in combination ...

https://en.wikipedia.org/wiki/Anorectic

Typically the CNS depressant within these combination drugs was a single barbiturate salt, especially pentobarbital sodium and ... The medical justification for these combination drugs was that the CNS stimulant elevates mood and suppresses appetite, while ... often with a CNS depressant. The recall also included all existing stocks of parenteral amphetamines based on the FDA's ... the CNS depressant mitigates many of the adverse effects of the CNS stimulant without simultaneously reducing its therapeutic ...

https://en.wikipedia.org/wiki/Desbutal

It usually consists of restlessness, nausea and vomiting, decreased appetite, tachycardia, insomnia, tremor, hallucinations, ... A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or ... Depressants also act to produce anesthesia. Cannabis may sometimes be considered a depressant due to one of its components, ... Carbamate's (Felbamate Carisoprodol) are depressants that are similar to barbiturates. Depressants exert their effects through ...

https://en.wikipedia.org/wiki/Depressant

Orn claims her neighbor told her it was a powerful anti-depressant. Orn mentions that the medicine curbs her sexual appetite ...

https://en.wikipedia.org/wiki/Blissfully_Yours

... appetite changes, and difficulty concentrating. Alcohol can be a depressant which slows down some regions of the brain, like ... It may feature sadness, difficulty in thinking and concentration and a significant increase or decrease in appetite and time ... and that therefore anti-depressants don't work against the illness. However, such study was met with criticism from some ... no one should interrupt their treatment if they are taking any anti-depressant. Attribution (psychology) Biopsychosocial model ...

https://en.wikipedia.org/wiki/Depression_(mood)

There is still a debate on whether the miscarriage is due to the depressive disease state or the anti-depressant medication. A ... Reported benefits of medication include returned appetite, increased mood, increased energy, and better concentration. Side ... anti-depressant medication has been found to be extremely effective in treating antenatal depression. Patients can expect to ... indicating that the miscarriage may be associated with the psychological state of the mother rather than the anti-depressant. ...

https://en.wikipedia.org/wiki/Antenatal_depression

A study in 2012 tested Nelumbinis Semen, the seeds of the herb Nelumbo nucifera, and its anti-depressant effects on animals ... The most common adverse effects were decreased appetite, experienced by 23% of the dogs in the study, and lethargy, experienced ... Chung, Hwan-Suck; Lee, Hye Jeong; Shim, Insop; Bae, Hyunsu (2012-05-28). "Assessment of anti-depressant effect of nelumbinis ... The study found that after one month of daily administration of the tricyclic anti-depressant clomipramine, these compulsive ...

https://en.wikipedia.org/wiki/Separation_anxiety_in_dogs

It has an adverse effect profile similar to other central nervous system depressants. Even though Pregabalin is a depressant ... Common (1-10% of people with pregabalin): blurred vision, diplopia, increased appetite and subsequent weight gain, euphoria, ...

https://en.wikipedia.org/wiki/Pregabalin

It should not be taken with other central depressants like alcohol, as they can increase its risks. It should not be used for ... loss of appetite, and stomach pain. Diphenoxylate is rapidly metabolized to difenoxin; it is eliminated mostly in feces but ...

https://en.wikipedia.org/wiki/Diphenoxylate

The study conducted with the bed nucleus of the stria terminalis found that the endurance of the depressant effects was ... Emerging data suggests that THC acts via CB1 receptors in the hypothalamic nuclei to directly increase appetite. It is thought ... Kirkham TC, Tucci SA (2006). "Endocannabinoids in appetite control and the treatment of obesity". CNS Neurol Disord Drug ... appetite, pain-sensation, mood, and memory, and in mediating the pharmacological effects of cannabis. The ECS plays an ...

https://en.wikipedia.org/wiki/Endocannabinoid_system

CNS depressants: Sedative action is potentiated. Benzodiazepines may also cause additive muscle weakness. Combined oral ... decreased appetite, nausea, vomiting, abdominal cramps, and diarrhea.[medical citation needed] Liver side effects may be seen ...

https://en.wikipedia.org/wiki/Dantrolene

The US label for sodium oxybate has a black box warning because it is a central nervous system depressant (CNS depressant) and ... Between 1% and 10% of people experience nasal congestion, runny nose, or sore throat, loss of appetite, distorted sense of ... The US label for sodium oxybate also has a black box warning because it is a central nervous system depressant and may cause ... It should not be used with other drugs that are CNS depressants like alcohol or sedatives. Use with divalproex results in about ...

https://en.wikipedia.org/wiki/Sodium_oxybate

Sedatives have potent, dose-dependent CNS depressant effects. These drugs exert a calming effect and may also induce sleepiness ... decreased sleep and appetite. Stimulants may cause anxiety and paranoia as well. Addiction of benzodiazepines is diagnosed ... The classes of medications most commonly abused are opioids, central nervous system (CNS) depressants and central nervous ... Opioid painkillers exert CNS depressant effects by binding to opioid receptors. Its psychoactive properties potentially cause ...

https://en.wikipedia.org/wiki/Prescription_drug_addiction

This treatment includes cognitive behavioral therapy (CBT), anti-depressant medication, and combination therapy. A lot of ... an increase/decrease in appetite can provide clues as well), insomnia or hypersomnia, psychomotor agitation or psychomotor ...

https://en.wikipedia.org/wiki/Minor_depressive_disorder

Ringo grows close to Carmella as she treats him as an adult and he helps her to overcome her anti-depressant addiction. After ... When Rosetta catches Ringo using appetite suppressants, she tells Frazer about his condition. After nearly drowning during a ... Rosetta Cammeniti (Natalie Saleeba) catches Ringo taking appetite suppressants, which leaves her upset by the situation. Clark ...

https://en.wikipedia.org/wiki/Ringo_Brown

It is also used illicitly as an athletic performance enhancer, cognitive enhancer, appetite suppressant, and recreationally as ... Stimulants and antidepressants (sedatives and depressants) may increase (decrease) the drug effects of amphetamine, and vice ... Other potential physical side effects include appetite loss, blurred vision, dry mouth, excessive grinding of the teeth, ... Amphetamine withdrawal symptoms can include anxiety, drug craving, depressed mood, fatigue, increased appetite, increased ...

https://en.wikipedia.org/wiki/Adderall

Side effects of MAOIs include tremors, insomnia, increased appetite leading to weight gain, blurred vision, urinary retention, ... depressants from different pharmacological groups along with psychotherapy for at least 6-8 weeks or no clinical response to ...

https://en.wikipedia.org/wiki/History_of_electroconvulsive_therapy_in_the_United_States

... loss of appetite, increased sweating, discolouration of extremities, anxiety, paranoia and depression.: 13 When snorted, it can ... but these patients all reported using a central nervous system depressant, most commonly GHB, with mephedrone. The patients ...

https://en.wikipedia.org/wiki/Mephedrone

The most common side effects include nausea/vomiting, sweating, loss of appetite, dizziness, headache, increase in suicidal ... other anti-depressants, anti-convulsants, analgesics, antiemetic agents, anti-migraine medications, methylene blue, linezolid, ...

https://en.wikipedia.org/wiki/Serotonin–norepinephrine_reuptake_inhibitor

Those who use stimulant and depressant drugs are more likely to report adverse reactions from stimulant use, more likely to be ... Include the following: Depression Shaking Feeling unreal Appetite loss Muscle twitching Severe and debilitating insomnia Memory ... the high that benzodiazepines produce or more commonly they are used to either enhance the effects of other CNS depressant ... injecting stimulants and more likely to have been treated for a drug problem than those using stimulant but not depressant ...

https://en.wikipedia.org/wiki/Benzodiazepine_use_disorder

Symptoms of withdrawal commonly include nausea, vomiting, and loss of appetite. Other symptoms may include restlessness, ... Chlorpromazine can also potentiate the CNS depressant effects of drugs like barbiturates, benzodiazepines, opioids, lithium and ...

https://en.wikipedia.org/wiki/Chlorpromazine

Anti-depressants do not prevent recurrence. Several drug therapies have been used on patients with KLS, but none of them have ... Excessive appetite (hyperphagia) and unusual cravings are present in half to two thirds of cases. About half of patients, ... In 1815, there was a report of a young man who showed excessive appetite and prolonged sleep after experiencing a fever; this ... Levin noted that some patients displayed an intense appetite in addition to their persistent tiredness. MacDonald Critchley, ...

https://en.wikipedia.org/wiki/Kleine–Levin_syndrome

Cotreatment with CNS depressants such as the benzodiazepines can cause additive CNS depression. Co-treatment with thyroid ... increased appetite, and weight gain, all were not observed. Clinical evidence of H1 receptor antagonists and TCAs for the ... In general, sedating properties of anti-depressant agents are related to antagonism of serotonin 5HT2, histamines, and α-1 ... Alcohol may potentiate some of the CNS depressant effects of doxepin. Antihypertensive agents may have their effects mitigated ...

https://en.wikipedia.org/wiki/Doxepin

Severe headache, restlessness, irritability, loss of appetite, body aches, severe abdominal pain, nausea and vomiting, tremors ... given that morphine is a central nervous system depressant. Morphine has resulted in impaired functioning on critical flicker ... loss of appetite, and the beginning of intestinal cramping Stage IV, 24 h to 36 h after last dose: Increase in all of the above ... Recovery of appetite and normal bowel function, beginning of transition to postacute and chronic symptoms that are mainly ...

https://en.wikipedia.org/wiki/Morphine

The drug has also been used as an appetite suppressant in Europe. Propylhexedrine is not an amphetamine, though it is ... Antidepressants Depressants Hallucinogens Nootropics Psychoanaleptics The active ingredient in some OTC inhalers in the United ... Khat contains a monoamine alkaloid called cathinone, a "keto-amphetamine", that is said to cause excitement, loss of appetite, ... Rasmussen N (July 2006). "Making the first anti-depressant: amphetamine in American medicine, 1929-1950". J. Hist. Med. Allied ...

https://en.wikipedia.org/wiki/Stimulant

It is seen in insect processes in roles similar to in the human central nervous system, such as memory, appetite, sleep, and ... such as fluoxetine and sertraline anti-depressants, inhibit PMAT but at IC50 values which surpass the therapeutic plasma ... When humans smell food, dopamine is released to increase the appetite. But, unlike in worms, serotonin does not increase ... This halts their dopamine release, and thereby serotonin decreases appetite. Drugs that block 5-HT2C receptors make the body ...

https://en.wikipedia.org/wiki/Serotonin

It was used in the Soviet Union during the 1930s and 1940s as an anti-depressant (under the name Эфедрон-ephedrone). ... and causes appetite suppression.[citation needed] Users can easily forget to consume fluids leading to increased thirst and ...

https://en.wikipedia.org/wiki/Methcathinone

The feeling of increased appetite following the use of cannabis has been documented for hundreds of years, and is known ... While psychoactive drugs are typically categorized as stimulants, depressants, or hallucinogens, cannabis exhibits a mix of all ... Fride E, Bregman T, Kirkham TC (April 2005). "Endocannabinoids and food intake: newborn suckling and appetite regulation in ... or appetite for breast milk" and recent research has identified the endogenous cannabinoid system to be the first neural system ...

https://en.wikipedia.org/wiki/Effects_of_cannabis

Harm S (11 April 1967). "US Patent 3313687 - Appetite-suppressing and weight reducing composition". "4F-IVP". Cayman Chemical. ... Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ...

https://en.wikipedia.org/wiki/List_of_designer_drugs

... is used as a short-term sedative and anxiolytic for cats and dogs, sometimes used as an appetite stimulant. It can ... The impairment is worsened by consumption of alcohol, because both act as central nervous system depressants. During the course ... "Drugs Affecting Appetite (Monogastric)". The Merck Veterinary Manual. Archived from the original on 28 October 2012. Retrieved ... Overdoses of diazepam with alcohol, opiates or other depressants may be fatal. If diazepam is administered concomitantly with ...

https://en.wikipedia.org/wiki/Diazepam

Severely afflicted by internal conflicts; his loss of appetite for life, love of his wife, and external pressures; managing his ... Kramer, Peter D (21 December 1997). "What Ivanov Needs in the 90's Is an Anti-Depressant". New York Times. Retrieved 17 ...

https://en.wikipedia.org/wiki/Ivanov_(play)

Increasing attention, for instance, was paid to his appetite for the rich, heavy Southern cooking of his upbringing, foods such ... Cyril Wecht conducted a review of the reports and concluded that a combination of central nervous system depressants had ...

https://en.wikipedia.org/wiki/Elvis_Presley

When mice that showed depressive symptoms were administered anti-depressant drugs, their levels of p11 were found to increase ... appetite, sleep, and mood. Varying levels of serotonin found in the brain are associated with the development of mood disorders ... Antidepressant manipulations increase the p11 levels, whereas depressant manipulations reduce it. Therefore, in order to ...

https://en.wikipedia.org/wiki/S100A10

As with other benzodiazepines, temazepam produces additive CNS-depressant effects when coadministered with other medications ... Hyperhydrosis, hypotension, burning eyes, increased appetite, changes in libido, hallucinations, faintness, nystagmus, vomiting ...

https://en.wikipedia.org/wiki/Temazepam

Brecher, Edward M. (1972). Licit and Illicit Drugs: The Consumers Union Report on Narcotics, Stimulants, Depressants, Inhalants ... and additionally in 1992 as an appetite stimulant for treatment of AIDS-related weight loss. It was initially classified as a ...

https://en.wikipedia.org/wiki/Medical_cannabis_in_the_United_States

... trials have shown that these benefits often outperform placebos when used on their own or in conjunction with anti-depressants ... mood and anxiety are brought about less in patients relative to increases in symptoms relating to reduced activity and appetite ...

https://en.wikipedia.org/wiki/Depression_and_immune_function

... decreased appetite (and hence weight loss), increased locomotor activity (LMA) etc. In the United States, cocaine overdose is ... "SKF83959 is a novel triple reuptake inhibitor that elicits anti-depressant activity". Acta Pharmacologica Sinica. 34 (9): 1149- ... "Rosmarinus officinalis polyphenols produce anti-depressant like effect through monoaminergic and cholinergic functions ...

https://en.wikipedia.org/wiki/Serotonin–norepinephrine–dopamine_reuptake_inhibitor

MGA is frequently used as an appetite stimulant to promote weight gain. The direct mechanism of appetite enhancement is unclear ... Tisell LE, Salander H (February 1975). "Androgenic properties and adrenal depressant activity of megestrol acetate observed in ... Appetite stimulation is achieved with MGA with oral dosages of 400 to 800 mg/day. The optimal dosage with maximum effect for ... Appetite enhancement induced by megestrol acetate might be partly due to the inhibition of these Ca2+ channel currents, and the ...

https://en.wikipedia.org/wiki/Megestrol_acetate

Similarly to other intermediate-acting depressants, it may be used as hypnotic medication or in order to mitigate withdrawal ... appetite loss, hallucinations, delirium, seizures, tremor, stomach cramps, myalgia, agitation, palpitations, tachycardia, panic ... The toxicity of bromazepam in overdosage increases when combined with other CNS depressant drugs such as alcohol or sedative ... The impairment is worsened by consumption of alcohol, because both act as central nervous system depressants. During the course ...

https://en.wikipedia.org/wiki/Bromazepam

Symptoms of withdrawal commonly include nausea, vomiting, and loss of appetite. Other symptoms may include restlessness, ... FDA urges caution about withholding opioid addiction medications from patients taking benzodiazepines or CNS depressants: ... which may underlie its low propensity for appetite stimulation and weight gain. The drug also has negligible affinity for the ...

https://en.wikipedia.org/wiki/Lurasidone

Anxiolytics (CNS depressants such as benzodiazepines and barbiturates): Kava may have potential additive CNS depressant effects ... loss of appetite and indigestion. These adverse health effects, while significant, are considered to be reversible upon ... CNS depressants such as benzodiazepines), antipsychotics, levodopa, diuretics, and drugs metabolized by CYP450 in the liver. A ...

https://en.wikipedia.org/wiki/Kava

In particular, amphetamine may decrease the effects of sedatives and depressants and increase the effects of stimulants and ... Other potential physical side effects include appetite loss, blurred vision, dry mouth, excessive grinding of the teeth, ... Amphetamine withdrawal symptoms can include anxiety, drug craving, depressed mood, fatigue, increased appetite, increased ...

https://en.wikipedia.org/wiki/Dextroamphetamine

Some early symptoms include tiredness, weakness, loss of appetite, weight loss, and nausea. People may also feel discomfort in ... These include several drugs such as anti-depressants, certain antibiotics, and NSAIDs (like ibuprofen). These agents are ... Early symptoms may include tiredness, weakness, loss of appetite, unexplained weight loss, nausea and vomiting, and discomfort ...

https://en.wikipedia.org/wiki/Cirrhosis

Early studies in rodents found that orexins (derived from Greek "orexis" meaning "appetite") stimulate appetite, feeding ... Dosage adjustment may be necessary when suvorexant is combined with other CNS depressants. Use of suvorexant in combination ... John's wort (expected to decrease suvorexant effectiveness). Coadministration of suvorexant with other CNS depressants such as ...

https://en.wikipedia.org/wiki/Suvorexant

... s are depressants that enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA ... Less common side effects include nausea and changes in appetite, blurred vision, confusion, euphoria, depersonalization and ... Combined with other central nervous system (CNS) depressants such as alcohol and opioids, the potential for toxicity and fatal ... ISBN 978-0-19-852748-0. McIntosh A, Semple D, Smyth R, Burns J, Darjee R (2005). "Depressants". Oxford Handbook of Psychiatry ( ...

https://en.wikipedia.org/wiki/Benzodiazepine

JavaScript is disabled for your browser. Some features of this site may not work without it ...

https://extranet.who.int/iris/restricted/browse?authority=Appetite+Depressants&type=mesh

La DL50 orale rapporté pour les souris est de 600 mg / kg, pour les rats est de 250 mg / kg et pour les chiens est de 225 mg / kg. Manifestation de surdosage aigu incluent lagitation, tremblements, hyperréflexie, respiration rapide, confusion, agressivité, hallucinations et les états de panique ...

https://pharmacycode.com/fr/Regenon_hydrochloride.html

Appetite Depressants / pharmacology * Behavior, Animal / drug effects* * Carbolines / pharmacology * Chlordiazepoxide / ...

https://pubmed.ncbi.nlm.nih.gov/3110839/?dopt=Abstract

Appetite Depressants Medicine & Life Sciences 19% * Gastric Emptying Medicine & Life Sciences 16% ... significant improvements occurred in appetite, bloating, constipation, vomiting, and diarrhea; and no patients required ... significant improvements occurred in appetite, bloating, constipation, vomiting, and diarrhea; and no patients required ... significant improvements occurred in appetite, bloating, constipation, vomiting, and diarrhea; and no patients required ...

https://jhu.pure.elsevier.com/en/publications/gastrointestinal-symptoms-in-anorexia-nervosa-a-prospective-study-4

This serves as a natural appetite suppressant and anti-depressant. Most people who are successful with weight loss and long- ... Exercises also decreases appetite and increases "feel good" hormone levels. ...

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Realize that looking at fungus-colored toes is an excellent appetite depressant. Decide that if you need appetite control at ...

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APPETITE DEPRESSANT 95140 FLUVASTATIN 95142 PREMPRO 95143 SYN-RX. LIST OF DRUG ENTRY CODES AND NAMES IN NUMERIC ORDER (cont.). ... 1570.0 Appetite, abnormal 1570.1 Excessive appetite Eats too much Always hungry 1570.2 Decreased appetite Not hungry Loss of ... 1150.0 Abnormal drug usage Includes: Drug abuse Frequent or excessive use of stimulants, hallucinogens, depressants, etc. ... appetite. 1580.0 Gastrointestinal bleeding 1580.1 Blood in stool (melena) 1580.2 Vomiting blood (hematemesis) 1585.0 Flatulence ...

https://wonder.cdc.gov/wonder/sci_data/surveys/namcs/type_txt/namcs97.asp

What causes the weight gain associated with anti-depressant drugs: slowed metabolism, increased appetite, increased insulin ... Are there healthy supplements that can increase my metabolism and decrease my appetite, or something like that?. 1 doctor ...

https://www.healthtap.com/questions/110619-is-it-possible-for-insulin-to-increase-metabolism-helping-me-to-lose-weight/

Some medications like anti-depressants can cause weight gain by increasing your appetite and slowing down your metabolism. ...

https://americaswire.org/why-am-i-gaining-weight-when-i-barely-eat/

... appetite stimulant buclizine, anti-depressant flupenthixol+melitracen and painkiller aceclofenac+drotavarine. He also sought a ... The health ministry on December 13 banned the use of buclizine as an appetite stimulant, nearly a week after the courts order ... While the government last week banned buclizine for appetite stimulation, the rest of the drugs are still available in the ... to support the use of buclizine as an appetite stimulant for children. DTAB has made "repeated" recommendations to prohibit the ...

https://economictimes.indiatimes.com/news/politics-and-nation/delhi-high-court-seeks-government-reply-on-unsafe-drugs-ban-plea/articleshow/67186567.cms

Appetite Depressant Appetite Depressing Drug Appetite Depressing Drugs Appetite Suppressant Appetite Suppressant Drug Appetite ... Appetite-Depressing Drugs Appetite-Suppressant Drug Appetite-Suppressant Drugs Depressant, Appetite Depressants, Appetite Drug ... Appetite-Depressing Drugs. Appetite-Suppressant Drug. Appetite-Suppressant Drugs. Depressant, Appetite. Depressants, Appetite. ... Appetite Depressant. Appetite Depressing Drug. Appetite Depressing Drugs. Appetite Suppressant. Appetite Suppressant Drug. ...

https://decs.bvsalud.org/en/ths/resource/?id=1073

1 Appetite Depressants --administra.... *1 Cyclobutanes --administration & d.... *. next > IMSEAR is the collaborative product ...

https://imsear.searo.who.int/handle/123456789/1/simple-search?query=&sort_by=score&order=desc&rpp=10&filter_field_1=dateIssued&filter_type_1=equals&filter_value_1=%5B2000+TO+2009%5D&filter_field_2=author&filter_type_2=equals&filter_value_2=Kumar%2C+A&filter_field_3=subject&filter_type_3=equals&filter_value_3=Middle+Aged&filter_field_4=dateIssued&filter_type_4=equals&filter_value_4=2001&etal=0&filtername=subject&filterquery=Prospective+Studies&filtertype=equals

Intentional central appetite depressant overdose (disorder). Code System Preferred Concept Name. Intentional central appetite ...

https://phinvads.cdc.gov/vads/ViewCodeSystemConcept.action?oid=2.16.840.1.113883.6.96&code=295811007

Appetite Depressants (‎1)‎. Argentina (‎1)‎. Benzbromarone (‎1)‎. China (‎1)‎. Chromans (‎1)‎. Cisapride (‎1)‎. ...

https://apps.who.int/iris/handle/10665/26722/search-filter?filtertype_0=mesh&filtertype_1=dateIssued&filter_relational_operator_1=equals&filter_relational_operator_0=authority&filter_1=%5B2000+TO+2019%5D&filter_0=Pharmaceutical+Preparations&field=mesh

However, you will also see the seeds mentioned in many weight loss formulas as this is an effective appetite depressant. It ... The plant has been used medicinally for its stimulants, nervine, astringent, and appetite depressant properties. Its main ... promotes weight loss by the dual action of reducing appetite and improving metabolism. ...

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... but to help her he would prescribe an appetite depressant, Dexedrine, to be taken before breakfast. ... It reduces appetite by activating a type of serotonin receptor known as the 5-HT2C receptor in a region of the brain called the ... My experience with "appetite suppressors" in the 79s was a nightmare. Only now at age 73 am I able to recognize the extreme ... These include hunger, appetite increase and weight gain.. But I would be more worried about the range of cognitive problems - ...

https://rxisk.org/a-blast-from-the-past-amphetamines-for-weight-loss/

Appetite Depressants 20% 23 Scopus citations * Epidemiologic and clinical updates on impulse control disorders: A critical ...

https://einstein.pure.elsevier.com/en/persons/eric-hollander/publications/?ordering=title&descending=false&page=3

Appetite depressant.. MITCHELLA. Dysuria with dysmenorrhea; or with congestive prostate enlargements in. sedentary males.. ... Appetite depressant.. Hangover, in general.. Headache, migraine, vasoconstrictor.. Headache, reflex uterine, with throbbing ... Appetite poor, nervous, weak (with Trifolium).. Hysteria with adrenergic-induced exhaustion.. BAPTISIA. Tongue full & deeply ... Constipation with poor appetite, post- febrile.. Asecretory dyspepsia with anorexia, atonicity.. Anorexia from cancer therapy. ...

https://italisvital.info/specific-indications-for-herbs-in-general/

Is marijuana an appetite stimulant?. Cannabis ability to stimulate appetite is well known on a casual level, but clinical ... What makes marijuana a depressant or a stimulant?. What makes marijuana a depressant or a stimulant?. But after all these years ... Nicotine seems to provide both a stimulant and a depressant effect, and it is likely that the effect it has at any time is ... Cannabis cant be definitively placed in a major drug category, but some people consider it a depressant with stimulant ...

https://searchandrestore.com/what-makes-marijuana-a-depressant-or-a-stimulant/

Depressants Epinephrine Injection are psychoactive drugs that affect the central nervous system (CNS). So it is essential that ... Buying Epinephrine Injection depressants reduce or completely eliminate appetite. However, while some stimulants make you feel ... Many of the depressants are found in herbal how to get Epinephrine Injection containing how to get Epinephrine Injection ... Most doctors in the US will prescribe Epinephrine Injection to you if you are There are several different types of depressants ...

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Info Appetite Depressants. * Info Central Nervous System Agents. * Info Central Nervous System Stimulants ...

https://druginfo.nlm.nih.gov/drugportal/rn/1197-21-3

PHENTERMINE is used as an appetite depressant. Yes, there are no contra-indications. Look at me, PHENTERMINE was in 1990 which ... Ime, many find appetizers like soup (especially made from scratch with fresh ingredients) increase their appetite.. It is known ...

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... so it can act as an appetite depressant.. High blood sugar levels are often linked with obesity and creating abdominal fat, so ...

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Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Sympathomimetic is a drug.Reference standards ... Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Sympathomimetic is a drug.Reference standards ...

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Codeine can also cause nausea, vomiting, constipation, loss of appetite, drowsiness, confusion, sweating, itching, dry mouth, ... Category: Depressant. Also know as:. Codis500, Cough Syrup, Nurofen Plus/Max, Syrup ...

https://www.knowthescore.info/drug/codeine/

Cataluña Burn is an appetite depressant arranged through the Cataluña Fimbriation plant. Cataluña Burn so far has gotten ... which has been used like a characteristic appetite suppressant in India for an impressive time span. ...

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He prescribes anti-depressants which make me incredibly sick and cause loss of appetite. But wait, it gets worse. ... I am taken off anti-depressants and my birth control pill and put on a loading dose of blood thinners. This causes me to have ...

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Then distances were used as an expectorant, diuretic, and appetite depressants. 1991). ...

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Some medications like anti-depressants can cause weight gain by increasing your appetite and slowing down your metabolism. (americaswire.org)
This includes antidepressants, anti-depressants (for obsessive-compulsive disorder), appetite stimulants (eg, vardenafil) and sleeping aids (eg, dexedrine), testosterone injection morning or night. (abiteofvegan.com)
Avoid using anti-convulsants and antihistamines alongside anti-depressants, as they may worsen side effects, injecting steroids with air bubbles. (abiteofvegan.com)
Certain anti-depressants are also responsible for appetite loss. (thechannel46.com)
In the East Pole Kingdom, among the eight hundred miles of mountains outside the East Pole City, We, Gong Yuanchuan and the I found a anti depressants are an appetite suppressant mountains. (glamour-nails.org)

The plant has been used medicinally for its stimulants, nervine, astringent, and appetite depressant properties. (botano.gr)
Most people understand that sleeping pills and sedatives, like Xanax and Valium, are depressants, whereas caffeine and cocaine are stimulants. (searchandrestore.com)
Even if we do not have a licensed doctor to guide buying Epinephrine Injection, we can assist you to treat whatever is In general, buying Epinephrine Injection have depressant effects while stimulants have stimulant effects. (sprayflexsprayers.com)
Two of the most common drug classifications are depressants and stimulants. (paracelsus-recovery.com)
With continued use of depressants or stimulants, the body builds up a tolerance for the drug. (paracelsus-recovery.com)
Combining depressants and stimulants is extremely risky. (paracelsus-recovery.com)
Withdrawal of depressants and stimulants is dangerous and detox must be medically supervised. (paracelsus-recovery.com)
There are many types of depressants and stimulants. (paracelsus-recovery.com)
Both depressants and stimulants can be addictive. (paracelsus-recovery.com)
People often use depressants to get rid of the unpleasant "upping" effect of stimulants and once a calming effect is reached, they "crash" and need "uppers" to even get going again. (paracelsus-recovery.com)
People addicted to stimulants and/or depressants, be it prescription medication, illegal drugs or alcohol, require careful and medically supervised detox and addiction treatment in order to be able to live a normal drug-free life again. (paracelsus-recovery.com)
Stimulants can also reduce your appetite, increase agitation, and induce sleepiness. (ardurecoverycenter.com)

The vet prescribed an anti-depressant in the hopes of stimulating her appetite. (funfoodlife.com)
I tried home remedies, every single over-the-counter pain killer ever made, I tried going to the doctor about them and was prescribed an anti-depressant that also helps with pain (umm, no thanks), and I tried anything and everything else in the book to help prevent or cure my migraines and nothing did the trick. (livinglikelinds.com)

You wouldn't have known that the use of amphetamines as appetite suppressants in the mid-twentieth century helped unleash an epidemic of addiction on both sides of the Atlantic, which by the 1970's led to several U.S. Congressional hearings on the amphetamine crisis . (rxisk.org)
But you need not be discouraged by the statistical data, as medical science has finally found a perfect solution to it - Appetite Suppressants . (iuventusmedcenter.com)
Here is what you need to know and understand about appetite suppressants. (iuventusmedcenter.com)
What Are Appetite Suppressants? (iuventusmedcenter.com)
Appetite suppressants are referred to as diet pills by professionals, and they are used specifically for reducing the excessive fat from the body and giving you a healthy body. (iuventusmedcenter.com)
How Do Appetite Suppressants Work? (iuventusmedcenter.com)
In medical terms, appetite suppressants are known as Anorectics. (iuventusmedcenter.com)
Are Appetite Suppressants Safe For The Body Health? (iuventusmedcenter.com)
Yes, certainly, appetite suppressants are completely safe for everyone. (iuventusmedcenter.com)
So you can totally rely on appetite suppressants for controlling excessive weight gain. (iuventusmedcenter.com)
What Are The Benefits Offered By Appetite Suppressants? (iuventusmedcenter.com)
The benefits of the appetite suppressants are extremely high, and it is essential for you to know how you can real the benefits offered by appetite suppressants . (iuventusmedcenter.com)
It has been proved by many researchers that appetite suppressants are helpful in reducing the overall weight of the body by 6 to 10 percent. (iuventusmedcenter.com)
The appetite suppressants are powerful enough to track the hunger pangs and keep control of them. (iuventusmedcenter.com)
When you consume appetite suppressants, the food intake frequency and quantity reduce. (iuventusmedcenter.com)
But this does not happen with appetite suppressants. (iuventusmedcenter.com)
Appetite suppressants could be the best way to do it. (iuventusmedcenter.com)
But if what are some good natural appetite suppressants.Wen Forgive He sighed and comforted Sisterinlaw, don't worry, let's take his handle, don't be afraid that he will make trouble again She shook homemade weight loss supplements bent over to pack things. (glamour-nails.org)
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What causes the weight gain associated with anti-depressant drugs: slowed metabolism, increased appetite, increased insulin resistance, other? (healthtap.com)

However, there are a lot of claims that it can treat various diseases such as nausea, pain, and loss of appetite. (drug.education)

Thakur, in his petition, asked the court to direct the Union health ministry to ban three drugs from the Indian market -- appetite stimulant buclizine , anti-depressant flupenthixol+melitracen and painkiller aceclofenac+drotavarine. (indiatimes.com)
The health ministry on December 13 banned the use of buclizine as an appetite stimulant, nearly a week after the court's order. (indiatimes.com)
As early as 2013, the health ministry's New Drugs Approval Committee (NDAC) found "no convincing literature" to support the use of buclizine as an appetite stimulant for children. (indiatimes.com)
What makes marijuana a depressant or a stimulant? (searchandrestore.com)
Cannabis can't be definitively placed in a major drug category, but some people consider it a depressant with stimulant properties. (searchandrestore.com)
Is tobacco classified as a stimulant or a depressant? (searchandrestore.com)
Nicotine seems to provide both a stimulant and a depressant effect, and it is likely that the effect it has at any time is determined by the mood of the user, the environment and the circumstances of use. (searchandrestore.com)
Studies have suggested that low doses have a depressant effect, whilst higher doses have stimulant effect. (searchandrestore.com)
Is marijuana an appetite stimulant? (searchandrestore.com)
Cannabis' ability to stimulate appetite is well known on a casual level, but clinical trials on medical marijuana as an appetite stimulant provide scientific evidence as well. (searchandrestore.com)
Other medications include the anti-depressant fluoxetine, the appetite stimulant Ritalin and more, what is the best sarms for bulking. (ichikawa-yusanbako.com)

Anxiety can sometimes result in decreased appetite. (thechannel46.com)

All of these different types of depressants and hypnotics affect moods and behaviour. (sprayflexsprayers.com)

But this finding shows that it is feasible to alter parts of the leptin-serotonin pathway to decrease appetite without weakening bone. (nutritionreview.org)
Supplements To Decrease Appetite. (glamour-nails.org)
Weight loss is commonly accompanied by decrease appetite, but cancer patients who are eating adequate amount of food still can experience weight loss due to increases in inflammation and body metabolism. (chemoexperts.com)

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Phentermine is an appetite suppressant used along with diet, exercise, and behavior therapy for the short-term management of obesity. (cheapmeds4u.com)

Bacterial, viral and fungal infections like the common flu and cold, food poisoning, gastroenteritis, and colitis can often suppress your appetite. (thechannel46.com)

Downers (depressants) do just the opposite. (medlineplus.gov)

Loss of appetite is a common side effect of certain medications. (thechannel46.com)
While these medications can increase appetite and improve mood, they can also cause drowsiness, dry mouth, difficulty thinking and, in some cases, can cause extreme paranoia or hallucinations. (chemoexperts.com)

The primary active compound in cannabis, tetrahydrocannabinol or THC, is believed to be the single most active chemical in cannabis' ability to stimulate appetite. (searchandrestore.com)
Corticosteroids can be given to help stimulate appetite by decreasing inflammation and increasing signals the body uses to increase appetite. (chemoexperts.com)
Mirtazapine is an anti-depressant but can help stimulate appetite by blocking a receptor in the brain which results in increased food intake. (chemoexperts.com)

The side-effects include fatigue, any type of change in the weight or appetite or diarrhea. (138315.net)

Iron is an extremely important essential element and its deficiency causes anaemia, which can be responsible for the lack of appetite. (thechannel46.com)
Symptoms include sleeping or eating too much, not being able to sleep, lack of appetite or craving carbohydrates, especially sweets. (unchealthcare.org)
This strain can be beneficial for those dealing with discomfort, a lack of appetite, insomnia, sadness, and stress, as it frequently reduces stress. (farmerslabseeds.com)

CNS Depressants: Trazodone may enhance effects of alcohol, barbiturates, or other CNS depressants ( 7 ). (nih.gov)
for this high percentage is likely due to the depressant effects of alcohol. (1library.net)

Marijuana and alcohol are also depressants. (paracelsus-recovery.com)
Prescription cannabinoids contain the active ingredient in marijuana, tetrahydrocannabinol (THC), which stimulates appetite. (chemoexperts.com)
Cannabis drugs such as marijuana may cause relaxation, impaired motor skills, and increased appetite. (medlineplus.gov)

Overdosing on depressants, opiates (like heroin and morphine), and minor tranquilizers affects your concentration and coordination, making everyday tasks impossible and even dangerous. (ardurecoverycenter.com)

In a study on rats, Kratom showed positive results on inhibiting the hypothalamus, responsible for appetite and hunger. (thebestfashion.co)

Constipation with poor appetite. (italisvital.info)

While the government last week banned buclizine for appetite stimulation, the rest of the drugs are still available in the Indian market. (indiatimes.com)
Amphetamine and Psychostimulant Drugs Amphetamine, methamphetamine, and dextroamphetamine are powerful analeptics that are used because of their psychostimulant and appetite depressant effects. (meatandsupplyco.com)
The actions of some appetite-depressant drugs such as fenfluramine, are reduced by administration of vitamin C. (healthysolutionstx.com)
Neobes 75mg is a appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. (bestsuppliermeds.com)
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Commonly prescribed depressants include drugs commonly known as Benzodiazepines or in short "Benzos" and Morphine. (paracelsus-recovery.com)

Furthermore, leptin was found to not act in the hypothalamus as previously thought, but in the brain stem acting on serotonin, a hormone that in the brain acts to control appetite, mood and anger. (nutritionreview.org)
Appetite is influenced by many reasons ranging from mood and emotions to mental and physical health. (thechannel46.com)

It has nothing to do with me Wen Liang turned around and motioned what can suppress appetite The womenaoning bit her lower lip and swung her best otc appetite suppressant and fat burner 2021 . (glamour-nails.org)

Dr. Karsenty points out that these current findings may have more influence on developing a new way to reduce appetite and obesity than preventing osteoporosis. (nutritionreview.org)
In the past they were used to treat obesity by decreasing appetite. (paracelsus-recovery.com)

This medication blocks the action of serotonin, which can suppress appetite. (chemoexperts.com)

It promotes weight loss by the dual action of reducing appetite and improving metabolism. (botano.gr)
New research from Columbia University Medical Center has illuminated a previously unknown leptin-serotonin pathway in the brain that simultaneously promotes appetite and bone mass accrual. (nutritionreview.org)
Eating small meals at regular intervals promotes healthy digestion, which aids in improving the appetite. (thechannel46.com)

Megestrol is thought to increase appetite by releasing hormones that promote appetite and by decreasing inflammation as well. (chemoexperts.com)

Amitriptyline is commonly prescribed as an anti-depressant and is used for the treatment of major depression. (fastmedstore.com)

Alcohol is a CNS depressant. (medscape.com)
Although we believe alcohol relaxes us, it's actually a depressant. (unchealthcare.org)

Infants, young children, and pregnant and lactating women are at a greater risk of zinc deficiency and one of the most common symptoms of zinc deficiency is loss of appetite. (thechannel46.com)
Episodes may be accompanied by various somatic symptoms including psychomotor retardation, agitation, loss of appetite, weight loss, and loss of libido. (cdc.gov)

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The stress response can affect your stomach and digestive tract, leading to loss of appetite or no appetite. (thechannel46.com)
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In other cases, the most common approach to addressing weight loss is to increase appetite and therefore increase the total amount of calories that are eaten per day to make up for the increase in calories that are being used up by the body. (chemoexperts.com)

It may only have a mild effect of stimulating appetite and can cause excessive drowsiness. (chemoexperts.com)

Buying Epinephrine Injection depressants reduce or completely eliminate appetite. (sprayflexsprayers.com)
As a result, they can lose interest in cooking or eating food which can reduce their appetite. (thechannel46.com)
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Adipex Retard 75mg is an appetite suppressant of a pharmacological group of amphetamines and phenethylamines. (bestsuppliermeds.com)

Although any scientist will tell you that cannabis is hard to classify, most people tend to view it as a hallucinogen crossed with a depressant. (searchandrestore.com)

2) Hariyanto TI and Kurniawan A. Appetite problem in cancer patients: Pathophysiology, diagnosis, and treatment . (chemoexperts.com)

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If you have been having trouble eating well, here is how to increase appetite for a healthier and happier life. (thechannel46.com)

When the leptin-serotonin pathway is turned on in mice, the researchers found, appetite increases, the animals eat more, gain weight, and their bone mass increases. (nutritionreview.org)
Though obese people produce high levels of leptin, they are resistant, or unresponsive, to its signals - instead, they operate in a false state of leptin deficiency, which increases serotonin - and thereby, appetite and bone mass. (nutritionreview.org)
Dr. Karsenty and his colleagues were surprised to observe that increased serotonin in the brainstem also increased appetite in mice. (nutritionreview.org)
Dr. Karsenty's team found that the appetite and bone pathways diverge once serotonin is released: one set of serotonin receptors turns on appetite, while a second increases bone mass accrual. (nutritionreview.org)

Not particularly sympathetic about her weight problem, the doctor told her she had to diet, but to help her he would prescribe an appetite depressant, Dexedrine, to be taken before breakfast. (rxisk.org)

Are there healthy supplements that can increase my metabolism and decrease my appetite, or something like that? (healthtap.com)

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. (pharmaffiliates.com)

Finally, in April of 2010, my weight doctor said I needed to exercise, lose weight and give up my appetite suppressant because it was doing the opposite of my current anti depressant. (stopthethyroidmadness.com)

Your emotional state affects appetite which in turns results in weight problems. (daveswordsofwisdom.com)

We were so hopeful that the drug would jumpstart her appetite but it never did. (funfoodlife.com)
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It also increases the appetite and boosts metabolism, keeping you attentive throughout the day. (thechannel46.com)

The appetite suppressant contains fiber in large quantities. (iuventusmedcenter.com)
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Kratom also works as an effective anti-depressant. (thebestfashion.co)

Anatomy1

Organisms3

Diseases4

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Psychiatry and Psychology8

Phenomena and Processes15

Technology, Industry, Agriculture1

Health Care1

Thermogenic effects of sibutramine and its metabolites. (1/354)

Use of dexfenfluramine, fenfluramine and phentermine and the risk of stroke. (2/354)

Amphetamine and fenproporex levels following multidose administration of fenproporex. (3/354)

Pharmacologic induction of weight loss to treat type 2 diabetes. (4/354)

Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. (5/354)

Studies on the role of serotonin receptor subtypes in the effect of sibutramine in various feeding paradigms in rats. (6/354)

Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. (7/354)

The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci. (8/354)

Appetite Depressants

Appetite

Appetite Regulation

Appetite Stimulants

Myocardial Depressant Factor

Depression, Chemical

Satiation

Hunger

Satiety Response

Ghrelin

Meprobamate

Central Nervous System Depressants

Anorexia

Eating

Pentobarbital

Peptide YY

Barbiturates

Feeding Behavior

Drinking

Scorpion Venoms

Energy Intake

Thirst

Metergoline

Hypnotics and Sedatives

Enflurane

Peptide Hormones

Diethylpropion

Leptin

Anesthetics

Meals

Desipramine

Iontophoresis

Muscle Relaxants, Central

Dose-Response Relationship, Drug

Bemegride

Halothane

Hypothalamus

Fenfluramine

Gastrointestinal Hormones

Cats

Nialamide

Scorpions

Isoflurane

Chlorpromazine

Aminobutyrates

Cholecystokinin

Respiration

Secobarbital

Cross-Over Studies

Glucagon-Like Peptide 1

Pregnanes

Thiopental

Energy Metabolism

Postprandial Period

Diazepam

Body Weight

Obesity

Morphine

Drug Interactions

Food Preferences

Naloxone

Time Factors

Electric Stimulation

Rats, Sprague-Dawley

Cachexia

Thermogenic effects of sibutramine and its metabolites. (1/354)

Use of dexfenfluramine, fenfluramine and phentermine and the risk of stroke. (2/354)

Amphetamine and fenproporex levels following multidose administration of fenproporex. (3/354)

Pharmacologic induction of weight loss to treat type 2 diabetes. (4/354)

Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. (5/354)

Studies on the role of serotonin receptor subtypes in the effect of sibutramine in various feeding paradigms in rats. (6/354)

Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. (7/354)

The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci. (8/354)

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