Lack of emotion or emotional expression; a disorder of motivation that persists over time.
Observable manifestations of impaired psychological functioning.
A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for circulatory disorders and in other applications as a D2 agonist.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
Mood or emotional responses dissonant with or inappropriate to the behavior and/or stimulus.
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
Intracranial tumors originating in the region of the brain inferior to the tentorium cerebelli, which contains the cerebellum, fourth ventricle, cerebellopontine angle, brain stem, and related structures. Primary tumors of this region are more frequent in children, and may present with ATAXIA; CRANIAL NERVE DISEASES; vomiting; HEADACHE; HYDROCEPHALUS; or other signs of neurologic dysfunction. Relatively frequent histologic subtypes include TERATOMA; MEDULLOBLASTOMA; GLIOBLASTOMA; ASTROCYTOMA; EPENDYMOMA; CRANIOPHARYNGIOMA; and choroid plexus papilloma (PAPILLOMA, CHOROID PLEXUS).
An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
A plant genus of the family POLYGALACEAE that contains onjisaponins, xanthones, pyrones, and benzophenones. The name is similar to other snakeroots such as ASARUM; SANICULA; ARISTOLOCHIA; AGERATINA; and others.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Sequential operating programs and data which instruct the functioning of a digital computer.
That branch of learning which brings together theories and studies on communication and control in living organisms and machines.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Activities concerned with governmental policies, functions, etc.
Individuals enrolled in a school or formal educational program.
Those factors which cause an organism to behave or act in either a goal-seeking or satisfying manner. They may be influenced by physiological drives or by external stimuli.
Educational institutions.
A system of government in which there is free and equal participation by the people in the political decision-making process.
Sound that expresses emotion through rhythm, melody, and harmony.
Modulation of human voice to produce sounds augmented by musical tonality and rhythm.
The use of music as an adjunctive therapy in the treatment of neurological, mental, or behavioral disorders.
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
All the organs involved in reproduction and the formation and release of URINE. It includes the kidneys, ureters, BLADDER; URETHRA, and the organs of reproduction - ovaries, UTERUS; FALLOPIAN TUBES; VAGINA; and CLITORIS in women and the testes; SEMINAL VESICLES; PROSTATE; seminal ducts; and PENIS in men.
A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
Systems developed for collecting reports from government agencies, manufacturers, hospitals, physicians, and other sources on adverse drug reactions.

Mutual gaze in Alzheimer's disease, frontotemporal and semantic dementia couples. (1/48)

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The Neuropsychiatric Inventory-Clinician rating scale (NPI-C): reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia. (2/48)

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Are the available apathy measures reliable and valid? A review of the psychometric evidence. (3/48)

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The trajectory of apathy after deep brain stimulation: from pre-surgery to 6 months post-surgery in Parkinson's disease. (4/48)

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Apathy, but not depression, reflects inefficient cognitive strategies in Parkinson's disease. (5/48)

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Treatment strategy in schizophrenia combined with eating disorder. (6/48)

Like any other patient, a schizophrenic patient can get a physical illness, too. As such patients tend to ignore reality and neglect themselves and are stigmatized by society, due to which their physical symptomatology is often ignored, physical illness can remain undetected. If the schizophrenic patient is observed and adequate care is provided by the family, family doctor and a psychiatrist, it is possible to recognize the physical illness and intervene promptly. We are presenting a case of a female patient who has been treated for schizophrenia for a number of years. The treatment was mostly ambulatory (i.e. the patient was hospitalized twice) and consisted of first-generation antipsychotics. During the past two years, for reasons unknown, the patient stopped taking regular meals and as a result lost significant body weight, became apathetic and withdrawn, started avoiding social contacts and neglected personal hygiene. She reportedly took the psychopharmaca regularly, but rarely attended psychiatric follow-up consultations. Due to substantial weight loss and hypotonia, correction of antipsychotic was made and internist treatment administered. The choice of olanzapine was not an accidental one. We decided to take advantage of its side effect for the treatment of an anorectic syndrome. Interdisciplinary cooperation proved to be a justified decision.  (+info)

A randomized clinical trial of theory-based activities for the behavioral symptoms of dementia in nursing home residents. (7/48)

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Physical activity attenuates neuropsychiatric disturbances and caregiver burden in patients with dementia. (8/48)

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In their recent study,3 Dr. Chow and her colleagues set out to localize clusters of apathy symptoms empirically, with actual patients with dementia, to see whether the affective, behavioural, or cognitive apathy symptoms tended to occur together or in isolation, and whether apathy typically co-occurs with other types of behavioural disturbances.. Dr. Chow showed combined data from Baycrest, Sunnybrook [Health Sciences Centre], UC San Francisco, and UCLA, showing results on the Neuropsychiatric Inventory (NPI). On the section of the NPI that deals with apathy, patients are questioned on spontaneous activity, spontaneity in conversation, participation in former activities, participation in former chores, demonstration of interest in others, investment in friends and family, and degree of affection.. Results showed that, for those with either FTD or Dementia of Alzheimers type (DAT), the most common type of apathy, when present, was a decrease in spontaneous activity. Comparing the percentage of ...
In their recent study,3 Dr. Chow and her colleagues set out to localize clusters of apathy symptoms empirically, with actual patients with dementia, to see whether the affective, behavioural, or cognitive apathy symptoms tended to occur together or in isolation, and whether apathy typically co-occurs with other types of behavioural disturbances.. Dr. Chow showed combined data from Baycrest, Sunnybrook [Health Sciences Centre], UC San Francisco, and UCLA, showing results on the Neuropsychiatric Inventory (NPI). On the section of the NPI that deals with apathy, patients are questioned on spontaneous activity, spontaneity in conversation, participation in former activities, participation in former chores, demonstration of interest in others, investment in friends and family, and degree of affection.. Results showed that, for those with either FTD or Dementia of Alzheimers type (DAT), the most common type of apathy, when present, was a decrease in spontaneous activity. Comparing the percentage of ...
ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers dementia. Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimers Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months.. ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. Safety will also be measured by examining neuropsychiatric symptoms other than apathy using the Neuropsychiatric Inventory (NPI).. Changes from baseline to 6 months in other neuropsychological assessments as measured using the Dementia Apathy Interview and Rating (DAIR) scale will also be assessed.. Cost-effectiveness will be measured by ...
ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers dementia. Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimers Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months.. ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. Safety will also be measured by examining neuropsychiatric symptoms other than apathy using the Neuropsychiatric Inventory (NPI).. Changes from baseline to 6 months in other neuropsychological assessments as measured using the Dementia Apathy Interview and Rating (DAIR) scale will also be assessed.. Cost-effectiveness will be measured by ...
TY - JOUR. T1 - Apathy is associated with ventral striatum volume in schizophrenia spectrum disorder. AU - Roth, Robert M.. AU - Garlinghouse, Matthew A.. AU - Flashman, Laura A.. AU - Koven, Nancy S.. AU - Cara Pendergrass, J.. AU - Ford, James C.. AU - McAllister, Thomas W.. AU - Saykin, Andrew. PY - 2016. Y1 - 2016. N2 - Apathy is prevalent in schizophrenia, but its etiology has received little investigation. The ventral striatum (VS), a key brain region involved in motivated behavior, has been implicated in studies of apathy. We therefore evaluated whether apathy is associated with volume of the VS on MRI in 23 patients with schizophrenia using voxel-based morphometry. Results indicated that greater self-reported apathy severity was associated with smaller volume of the right VS even when controlling for age, gender, depression, and total gray matter volume. The finding suggests that apathy is related to abnormality of brain circuitry subserving motivated behavior in patients with ...
OBJECTIVES: Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimers disease (AD), associated with greater functional decline and caregiver distress. The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. METHODS: Semi-structured interviews were conducted with 111 AD patients and their caregivers as part of the European multi-centre study AddNeuroMed. Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T MRI scanner and the images analysed using an automated analysis pipeline. RESULTS: We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and
OBJECTIVES: Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimers disease (AD), associated with greater functional decline and caregiver distress. The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. METHODS: Semi-structured interviews were conducted with 111 AD patients and their caregivers as part of the European multi-centre study AddNeuroMed. Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T MRI scanner and the images analysed using an automated analysis pipeline. RESULTS: We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and
Background: Geriatric depression with subjective memory complaints increases the risk for Alzheimers Disease. Memantine, a neuroprotective drug, can improve depression and help prevent cognitive decline. In our 6-months clinical trial, escitalopram/memantine (ESC/MEM) improved mood and cognition compared to escitalopram/placebo treatment (ESC/PBO; NCT01902004). In this report, we investigated whether baseline brain white matter integrity in fronto-limbic-striatal tracts can predict clinical outcomes using fractional anisotropy (FA).Methods: Thirty-eight older depressed adults (mean age = 70.6, SD = 7.2) were randomized to ESC/MEM or ESC/PBO and underwent diffusion-weighted imaging (DWI) at 3 Tesla at baseline. Mood was assessed using the Hamilton Depression Rating Scale (HAMD), apathy using the Apathy Evaluation Scale (AES) and anxiety using the Hamilton Anxiety Scale (HAMA) at baseline and 6-months follow-up. FA was extracted from seven tracts of interest (six in each hemisphere and one commissural
For the study, researchers examined 79 adolescents ages 14 to 18, who were classified as recent regular cannabis users (36) or light users (43). Frequency and amount of substance use were assessed across participants lifetime and during the past 30 days, and motivation was measured through the Apathy Evaluation Scale and Motivation and Engagement Scale. To examine associations between cannabis use (CU) and motivation indices, researchers conducted a series of two-step hierarchical multiple regressions.. After controlling for confounds, no significant differences were observed between regular and light users on any motivation index, states the study. Similarly, no associations between motivation and lifetime or past 30-day CU amount were observed.. The study concludes by stating; Our findings do not support a link between reduced motivation and CU among adolescents after controlling for relevant confounds.. The full study, conducted by researchers at Florida International University, ...
January 29, 2010. Most people think of memory loss when they think of Alzheimers. But the disease can cause a wide range of behavioral and personality changes as well. One of the most common is apathy, or loss of motivation, and the condition seems to have a biological basis. Using brain scans, researchers in Sweden report that changes in the brains white matter are a common feature in apathetic patients who have Alzheimers or other forms of dementia.. Apathy is one of the most common psychological problems associated with dementia. Just over half of all people with Alzheimers are emotionally blunted and lack motivation and initiative. As the disease worsens, apathy often grows worse.. Studies suggest there is a common biological reason behind apathy, irrespective of whether a person has Alzheimers or other forms of dementia. The changes occurred in areas deep in the brain that are connected to the brains frontal lobes, which are critical for taking initiatives and the ability to ...
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Apathy. It has become a major issue for so many people today. While many people associate apathy with a lack of passion or motivation, it is technically defined as the absence of emotion.
Apathy Just Begun lyrics & video : [Funkmaster flex sample] [Celph Titled] Yo what the f**k are yall thinkin Lettin Apathy get on the mic Thats like unleashing a f**king atom...
BACKGROUND: Alzheimers disease (AD) is characterized not only by cognitive and functional decline, but also often by the presence of neuropsychiatric symptoms. Apathy, which can be defined as a lack of motivation, is one of the most prevalent neuropsychiatric symptoms in AD and typically leads to a worse quality of life and greater burden for caregivers. Treatment options for apathy in AD are limited, but studies have examined the use of the amphetamine, methylphenidate. The Apathy in Dementia Methylphenidate Trial (ADMET) found that treatment of apathy in AD with methylphenidate was associated with significant improvement in apathy in two of three outcome measures, some evidence of improvement in global cognition, and minimal adverse events ...
A. H. Craig, J. L. Cummings, L. A. Fairbanks, L. Itti, B. L. Miller, J. Li, I. Mena, Cerebral blood flow correlates of apathy in Alzheimer disease, Archives of Neurology, Vol. 53, No. 11, pp. 1116-20, Nov 1996. [1998 impact factor: 3.375] (Cited by 231). Abstract: BACKGROUND: Apathy is a pervasive noncognitive neuropsychiatric disturbance in Alzheimer disease, which causes significant caregiver distress. The neuroanatomical substrate of apathy is not well understood. OBJECTIVE: To study the relationship between regional cerebral blood flow and the presence and severity of the personality disturbance, apathy, in individuals with Alzheimer disease. DESIGN: Analysis of the relationship between regional cerebral blood flow as measured by single photon emission computed tomography and severity of apathy as measured by the Neuropsychiatric Inventory using an analysis of variance design. We examined regional cerebral perfusion alterations as measured by xenon 133Xecalibrated technetium Tc 99m ...
k4140] High doses of dopamine are usually needed to help patients suffering from apathy. In one study, seven out of eight patients who became depressed following liver transplants and were given methylphenidate, or Ritalin, a drug that elevates dopamine levels, showed improved motivation in pursuing their rehabilitation regimens and less social withdrawal and apathy than they exhibited before taking the drug. For apathy patients, drugs are not the final cure. They also need assistance in practicing techniques to help themselves. Education of the family is an important job for the therapist, too. Treatment of apathy raises some complex human rights issues, because these patients may be competent enough to make some decisions but not others. They are also prone to anxiety, which must be relieved so that they will consider options and get involved with life again. Treating apathy is also important in depressed patients. Drugs can be used to bring about rapid improvement at an early stage. Since ...
TY - JOUR. T1 - Apathy is associated with activities of daily living ability in Parkinsons disease. AU - Laatu, S. AU - Karrasch, Mira. AU - Martikainen, K. AU - Marttila, R. PY - 2013. Y1 - 2013. M3 - Artikel. VL - 35. SP - 249. EP - 255. JO - Dementia and Geriatric Cognitive Disorders. JF - Dementia and Geriatric Cognitive Disorders. SN - 1420-8008. IS - 5. ER - ...
TY - JOUR. T1 - Apathy is associated with activities of daily living ability in Parkinsons disease. AU - Laatu, S. AU - Karrasch, Mira. AU - Martikainen, K. AU - Marttila, R. PY - 2013. Y1 - 2013. M3 - Artikel. VL - 35. SP - 249. EP - 255. JO - Dementia and Geriatric Cognitive Disorders. JF - Dementia and Geriatric Cognitive Disorders. SN - 1420-8008. IS - 5. ER - ...
Apathy is a debilitating and under-recognized condition that has a significant impact in many neurodegenerative disorders. In Parkinsons disease, it is now known to contribute to worse outcomes and a reduced quality of life for patients and carers, adding to health costs and extending disease burde …
Apathy is a non-motor symptom of Parkinson s disease that is sometimes misinterpreted as laziness, poor initiative or depression.
Author: Frisch, Stefan et al.; Genre: Journal Article; Published in Print: 2017-12; Title: Apathy and cognitive deficits in patients with transient global ischemia after cardiac arrest
(KudoZ) French to English translation of L ACEDIE: acedia (A mental disorder characterized by apathy and melancholia) [MEDICAL - Medical (general) (Medical)].
Immortal lyrics from Its The Bootleg Muthaf_ckas!: Vol.1 album and other Apathy songs, music. Its The Bootleg Muthaf_ckas!: Vol.1 cover.
Abstract: Objectives: People with Huntingtons disease (HD) experience poor social quality of life, relationship breakdown, and social withdrawal, which are mediated to some extent by socially debilitating neuropsychiatric symptoms, such as apathy and disinhibition. Social cognitive symptoms, such as impaired emotion recognition, also occur in HD, however, the extent of their association with these socially debilitating neuropsychiatric symptoms is unknown. Our study examined the relationship between emotion recognition and symptom ratings of apathy and disinhibition in HD. Methods: Thirty-two people with premanifest or symptomatic-HD completed Part 1 of The Awareness of Social Inference Test (TASIT), which is a facial emotion recognition task. In addition, we obtained severity ratings for apathy and disinhibition on the Frontal Systems Behavior Scale (FrSBe) from a close family member. Our analyses used motor symptom severity as a proxy for disease progression. Results: Emotion recognition ...
IUPsyS is psychologys international organization in Official Relations with the WHO and these were renewed in January 2014. In this capacity IUPsyS was appointed to the International Advisory Group (IAG) for the Revision of ICD-10 Mental and Behavioural Disorders in 2006 and Secretary General, Dr Ann Watts, currently represents the Union on the IAG. Psychologys contributions to the development of ICD-11 remain a key IUPsyS strategic priority. To support this important initiative the IUPsyS has seconded psychologist Dr Geoff Reed to the WHO to serve as Senior Project Officer for the Mental and Behavioural Disorders component of the ICD-10 revision. In this capacity Dr Reed reports to the Director of the WHO Department of Mental Health and Substance Abuse, Dr Shekhar Saxeena, and Dr Pierre Ritchie, Co-Main Representative (Psychology) to WHO. Dr Reeds work at WHO has been suported by major grants from the American Psychological Association (APA) to IUPsyS (2008-12; 2013-14;2015-6). The Agreement ...
Psychometric support was found for all 3 versions of the BFNE, although the longer 12-item BFNE-II did not improve measurement compared to the shorter 8-item versions (BFNE-S and BFNE-8). Of these 2, the BFNE-S has been more widely studied, with strong validity data in a greater number of population …
This study examined the brain bases of early human social cognitive abilities. Specifically, we investigated whether cortical regions implicated in adults perception of facial communication signals are functionally active in early human development. Four-month-old infants watched two kinds of dynamic scenarios in which a face either established mutual gaze or averted its gaze, both of which were followed by an eyebrow raise with accompanying smile. Haemodynamic responses were measured by near-infrared spectroscopy, permitting spatial localization of brain activation (experiment 1), and gamma-band oscillatory brain activity was analysed from electroencephalography to provide temporal information about the underlying cortical processes (experiment 2). The results revealed that perceiving facial communication signals activates areas in the infant temporal and prefrontal cortex that correspond to the brain regions implicated in these processes in adults. In addition, mutual gaze itself, and the ...
Objective: Aging societies will bring an increase in the number of long-term care patients with mental-physical multimorbidity (MPM). This paper aimed to describe the natural course of neuropsychiatric symptoms (NPS) in patients with MPM in the first 8 months after admission to a geronto-psychiatric nursing home (GP-NH) unit. Methods: Longitudinal cohort study among 63 patients with MPM no dementia living in 17 GP-NH units across the Netherlands. Data collection consisted of chart review, semi-structured interviews, and brief neuropsychological testing, among which our primary outcome measure the Neuropsychiatric Inventory (NPI). Descriptive and bivariate analyses were conducted. Results: Our study showed a significant increase of the NPI total score (from 25.3 to 29.3, p = 0.045), and the total scores of a NPI hyperactivity cluster (from 9.7 to 11.8, p = 0.039), and a NPI mood/apathy cluster (from 7.7 to 10.1, p = 0.008). Just over 95% had any clinically relevant symptom at baseline and/or six ...
The goal of this research was to evaluate the impact of ACES (Accompagnement Collaborative des Enseignants du Secondaire), a training program for high school teachers aimed at facilitating the educational integration of students with special needs. Offered individually or in groups, the program was well received by all stakeholders and had a positive impact on teachers, students and the classroom climate. The program positively influenced teachers attitudes towards their students, their understanding of behavioural disorders, their use of positive and proactive intervention strategies, and the student-teacher relationship.. Teachers who took part in the program had a significantly lower level of teaching stress than those in the control groups. While little difference was observed between the two versions of the program, the group training was more popular with all parties concerned.. ...
Psychiatric and Behavioural Disorders in Intellectual and Developmental Disabilities General Medical Ebook by Nick Bouras, Geraldine Holt,
A number of biological markers have been implicated in late life depression with inconsistent results. The present study examined the relationship between several serum based biomarkers and symptoms of depression in a sample of elderly women with AD or cognitively intact. Methods 171 females (58 with AD and 113 cognitively intact) were recruited from the Longitudinal Research Cohort of the Texas Alzheimers Research and Consortium (TARC). Stepwise regressions were conducted with GDS total and subscales and a panel of biomarkers (CRP, IL-10, IL-1α, TNF-α, ICAM-1, BDNF, and MIF). ApoE4 status was coded (carrier or non-carrier), and the results were analyzed by cognitive status (AD or controls). Results: None of the biomarkers significantly predicted total GDS score for AD cases, controls or sample as a whole. For the Controls, ICAM significantly predicted Dysphoria and level of Apathy. Among AD patients, MIF, ICAM, and CRP, were significantly associated with Apathy. MIF and ICAM were inversely
This mutation was identified in a Spanish family with AD that progressed relatively slowly, with a wide range of ages of onset (Lladó et al., 2010). A total of six family members were affected, with ages of onset ranging from the fifth to eighth decade of life. The mutation was found in all three affected members who were tested, and was absent from 121 controls and 163 AD patients.. The proband was a man who developed cognitive decline with behavioral abnormalities at age 57. His behavioral symptoms included apathy, irritability, social withdrawal, and, ultimately, marked aggressiveness for which he was institutionalized at age 70. Another family member carrying the mutation also initially presented with apathy and irritability, and subsequently became aggressive, but her symptoms started earlier, at age 42. Surprisingly, a third mutation carrier in the same family presented with typical AD at age 71. This is in contrast to the complete penetrance of PSEN1 mutations usually seen by age 65. All ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Psychic akinesia has been described in patients that are fully responsive, but with no display of goal directed activities. It is characteristic of patients with psychic akinesia to correctly perform most of their daily activities, but only after strong stimulation.42 A similar syndrome was labelled the autoactivation deficit by Laplane and Dubois, and was defined as a deficit in spontaneous activation of mental processing, observed in behavioural, cognitive or affective domains, which can be totally reversed by external stimulation that activates normal patterns of response.43 The authors listed the following symptoms of autoactivation deficit: (1) inertia (defined as the tendency to stay immobile for long periods and taking no initiatives), (2) mental emptiness (defined as lack of thoughts and no projections onto the future), (3) repetitive and stereotyped activities, (4) flat affect and (5) blunted emotional responses. Full reversal of the negative state on external stimulation was ...
Apathy is a subject near and dear to my own heart. I have shared before how hard Ohio winters are on me physically and mentally. I have come to realize that I do best when I fight back with a variety of tools such as happy lights, supplementation, outdoor time, exercise, and healthy foods. The kink in the otherwise perfect plan though can be aptly named, apathy. You may know what you need to do but you just cant work up the enthusiasm or energy to do it. You become indifferent to your … [Read more...] ...
Reduced alertness, fatigue, apathy, insomnia are often lumped together. As a rule in older folks, alertness aint what it used to be. [9] The exceptions are a wonderful thing to behold. I am surprised at finding a number of people as young as being in their fifties, who share with older folks the poor recall of names. If you think of the brain being like a computer, it is if something happened to the address book. You cant put names to the faces. Mental stress is a big contributor to the development of feeling fatigued. Multitasking is a problem. Not being able to breeze through tasks, as one did in mid-life, can prove very frustrating and stressful. Realizing that one person has little impact on the worlds problems, leads to apathy or to continue seeking solutions when in the twilight zone of sleep. Dry skin: A universal problem in older folks -- made worse from exposure to dry inside, winter air. [10] Moisturizing lotions seem to be the only remedy, but even with their use, break-through ...
What up, my punky little peanuts? This is the last installment of our three-part intro to Dead Broke Rekerds. So we have a whole other. Read more ...
The opposite of Apathy is Love. Last Saturday my husband and I joined four other couples for a dinner club and the discussion around the table was anything but apathetic. Jokes about the election year and the wild ride ahead for us Americans mingled with updates on our families and local parishes. Wine glasses clinked and Italian sauced plates scraped clean as five women and five men tried to predict how the public would soon vote and who our next president will be. The famous quote, Never talk politics or religion in polite company was disregarded and I believe with good reason. As Christians we care about our country, families and our churches and to sit back and do nothing would be considered apathetic. And apathy is the opposite of love.. Later in the evening when we resumed to the living room, the hostess presented our group with a challenge. Before Jesus ascended up to Heaven, He told his disciples to wait until the Holy Spirit has come down in power to help them. So for Ten days the ...
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But Gorakhpur is not the first such incident, and unless there is a deep dive to find and isolate the root cause, it wont be the last either
Dozens of US AIDS activists demonstrated at a world AIDS conference here Wednesday calling on White House candidates to commit to HIV prevention, as experts warned of emerging US public
Berlin (ots/PRNewswire) - - Vaccination apathy is a key barrier to protecting the community against infectious disease, according to global health experts - By 2060, 30% of...
Wednesday, April 4. 2007 Introduction The Palestinian environment and its natural resources have been under human pressure since the Israeli occupation of 1967. The division of the West Bank into areas A, B and C with different control authority is making environmental conditions more severe as the potential for environmental protection is diminished. Along with…
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Immortal Lyrics: {I am immortal, I have inside me blood of kings / I have no rival, no man can be my equal} / I spit, to make the mic like a flammable torch / Its understandable my mind is a
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In the last 4 years of funding we have defined the conditions under which T cells obviate the requirement for costimulatory signaling during activation, and med...
At the recent Patient Advocacy Conference I attended, I spoke with a community member. Weve previously met but Ive talked more with his family members. Hes always seemed to be rather shy.. He asked me how I motivate myself. Ive been asked this before. Many people with myotonic dystrophy experience both overwhelming physical fatigue as well as extreme apathy. The first time I attended the annual patient conference I participated in a panel discussion. Afterwards I had someone approach me with utter disbelief that I had the disease. Even though I appeared to be similar in age to her daughter, I appeared to function like a normal person.. The more you learn about the disease, the more you realize the diversity of symptoms and severity. Im sure there are many additional factors the research community doesnt take into account, i.e. my self-care routines are like a full-time job.. But getting back to this young man (age is relative and hes ~20 years my junior) and his question. There are ...
Recent events in the nation, perhaps most notably the We March protest that took place last week, showed that The Bahamas has begun to shake off the veil of apathy that we have slumbered under for what feels like too long. This year has been a belter for politics and people of all beliefs making their feelings known - for better or for worse. And, as art so often engages with the state of society, so it is that many of the submissions for the 8th National Exhibition (NE8) at the National Art Gallery of The Bahamas (NAGB) were brash, bold, opinionated, and deeply political; reflecting how strongly so many of us feel after the various events of 2016.
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University of Southern California DAILY @ TROJAN VOL. LXII NO. 89 LOS ANGELES, CALIFORNIA TUESDAY, MARCH 16, 1971 MARGARET MEAD Media causes apathy-Mead By JAN EDWARDS The media see campuses as dens of apathy. In fact, they bring about that state by a sort of cause-and-effect relationship. This is the observation of Margaret Mead, anthropologist and author, who said. The media say the campuses are calm, and in general the campuses are complying. At noon yesterday in Bovard Auditorium. Dr. Mead spoke to a near-capacity audience. Reviewing the past few years, she found you either have a bust or you have apathy. If youre not having a bust, then youre having apathy. But the campus image in the eye of the community is of marginal importance. she observed. The image students have of themselves is more important than the image that the media give to students. Students have been discouraged about the chances of accomplishing something. Dr. Mead believes that if an organized few are motivated ...
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Gwyn M. Vernon, M.S.N., R.N., C.R.N.P., is co-founder and national director of The Edmond J. Safra Visiting Nurse Faculty Program at the Parkinsons Foundation.. PLEASE NOTE: This web seminar is being hosted by the Parkinsons Foundation, and registration will be handled through their website, www.pdf.org.. *This web seminar is approved for AoTA contact hours in addition to CEUs approved for all ASA web seminars. Questions about registration? Call the Parkinsons Foundation at 800-457-6676.. Questions about CEUs? Call ASA at 415-974-9628.. Have technical issues? Call NetBriefings at 866-225-1532.. ...
I'm very interested to see how the 2008 presidential election affects the motivation levels of students this year. As this article in The Washington Post talks about, the 18-24 age group is notorious for being politically apathetic, particularly those who haven't gone to college, but some are hopeful that that might change. I know this is an issue that doesn't directly affect most high school students, since only a small percentage of them can participate in the voting process, but I do think a presidential election is one of the most exciting things that happens in this country, and even...
Groups consisting each of three males and three females received two i.p. injections of 2500 mg/kg separated by 24 h using an application volume of 10 ml/kg . In addition, two males were treated with an application volume of 20 ml/kg.Symptoms were recorded for up to 48 h (for males: apathy, roughened fur, emaciation, loss of weight, sunken flanks, spasm, difficulty in breathing, eyelids stuck together, slitted eyes, closed eyes, lachrymation, white tears and diarhoea; for females: apathy, roughened fur, emaciation, loss of weight, sunken flanks, spasm, shivering, slitted eyes, closed eyes) None of the animals died. Due to the results it was concluded, that there were no substantial differences between sexes. Therefore, no females were used in the definite study ...
This week on Slate I read a controversial piece: American Jews Are Secular, Intermarried, and Assimilated: Great News! which was written about the recent Pew study on American Jews. The author, Gabriel Roth, tells American Jewry to embrace their secular, intermarried selves and that unless theyre Orthodox and believe, theres no reason to keep this race purity going on. He explains that other than Orthodox Jews, Jews will stop existing soon, and thats a good thing. (Oy!) Roth writes:. And as an intermarried Jewish nonbeliever, I think its time we anxious Jews stopped worrying and learned to love our assimilated condition-even if it means that our children call themselves half-Jewish and our grandchildren dont consider themselves Jews at all. Im not talking, here, to religious Jews, because their position is unarguable: If you believe that Jewish traditions are part of a covenant with God, of course you want your children to continue them.. Roth and I both agree that staying Jewish for ...
ally sleep has been one of the hardest things to study, but some recent studies using a PET scan and a tagged amino acid may give us some clues as to why we need to sleep. One of the theories is that we need sleep to repair proteins in the cells of the brain, which cant happen while we are awake because the brain is too busy and has too many processes happening. During a normal day while we are awake we accumulate adenosine in our brain, which signals our bodies to sleep. Sleep would eliminate the adenosine and produce more proteins for repair of the brain cells.. Humans have varying levels of sleep, but so do many animals in nature. A normal human gets somewhere between 7 and 8 hours of sleep per night, but an animal such as a lion gets up to 15 hours a day. A elephant on the other hand gets around 4 hours of sleep. One of the theories about this is that predator species can sleep more because they dont generally have many predators, while the prey species get much less sleep so they can ...
ally sleep has been one of the hardest things to study, but some recent studies using a PET scan and a tagged amino acid may give us some clues as to why we need to sleep. One of the theories is that we need sleep to repair proteins in the cells of the brain, which cant happen while we are awake because the brain is too busy and has too many processes happening. During a normal day while we are awake we accumulate adenosine in our brain, which signals our bodies to sleep. Sleep would eliminate the adenosine and produce more proteins for repair of the brain cells.. Humans have varying levels of sleep, but so do many animals in nature. A normal human gets somewhere between 7 and 8 hours of sleep per night, but an animal such as a lion gets up to 15 hours a day. A elephant on the other hand gets around 4 hours of sleep. One of the theories about this is that predator species can sleep more because they dont generally have many predators, while the prey species get much less sleep so they can ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
This is another tragedy that once again reflects the sordid state of hospitals and health care through out India. News of deaths coming from Gorakhpur, Uttar Pradesh is spiralling on a daily basis and that too from just one hospital viz. BRD Hospital, the government-run hospital of the city. It is the only hospital with reasonable faciliities in a 300-km radius and treats encephalitis patients from Gonda, Basti districts, Terai region in Nepal and eastern districts of Bihar. No State can be shown as a model. Like the farmers, the children of the poor in the India are totally neglected. 70 years of our growth of free India is yet to reach them.. A small town named Gonda in UP was at the last position among 434 cities surveyed across the country. It shall also be remembered that Gonda district is among the 10 districts in UP severely affected by Encephalitis. All this means that hygiene is one of the crucial factors in containing encephalitis, and the total failure of administration in this ...
COLLEGE STATION The more you know the less you care at least that seems to be the case with global warming. A telephone survey of 1,093 Americans by two Texas A&M University political scientists and a former colleague indicates that trend, as explained in their recent article in the peer-reviewed journal Risk Analysis. More informed respondents both feel less personally responsible for global warming, and also show less concern for global warming, states the article, titled Personal Efficacy, the Information Environment, and Attitudes toward Global Warming and Climate Change in the USA.. The study showed high levels of confidence in scientists among Americans led to a decreased sense of responsibility for global warming.. The diminished concern and sense of responsibility flies in the face of awareness campaigns about climate change, such as in the movies An Inconvenient Truth and Ice Age: The Meltdown and in the mainstream medias escalating emphasis on the trend.. The research was ...
While these efforts are of monumental importance, theyre merely Band-Aids covering the wounds of privatization. Even before Trumps ascent to the presidency, the nature of internet oversight was historically laissez-faire, rendering the web an often predatory place ripe for commercial takeover. Governments have failed to regulate the internet as a public utility, furnishing it with unchecked invasive potential. Though the Federal Communications Commission (FCC) technically classified internet as a utility in 2015, it wasnt until late 2016 that the government barred ISPs from collecting such sensitive data as social-security numbers and healthcare information without explicit user consent--a law Americans now wont see come to fruition any time in the near future. The loss of such regulation is foreboding: these requirements were protocol for a communications utility; were a phone company to eavesdrop on a users call without that persons knowledge, it would be violating the law. Now, however, ...
​When it comes to empathy and sympathy, the problem is that many people cant seem to have either of them until awful shit happens to them as well. Maybe. Too many people are unwilling to make that mental, emotional leap to truly empathize with the unfortunate plight of others. No way we can initiate effective…
Apathy and fatigue may be caused by thyroid problem or hormone imbalance. Apathy and fatigue in endometriosis is caused by the pressure of coping with any sort of pain that returns relentlessly every month, affecting her physical and emotional state.
The climate is changing. Great Lakes organizations and officials are trying to make sure restoration work is done with this in mind. But climate change remains
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It was comfortable in his bed, so he decided to stay there.. It was still comfortable the next day, because it was so soft.. It was still comfortable the next week, because it was so warm.. It was still comfortable the next month, because he couldnt feel anything at all.. ...
The peak of tolerance is most readily achieved by those who are not burdened with convictions, Alexander Chase, Perspectives (1966) Romans 1:26 For this reason God gave them over to dishonorable passions. For their women exchanged the natural sexual relations for unnatural ones, 1:27 and likewise the men also abandoned natural relations with women and were inflamed in their passions for one another
A week or so ago, there was a large discussion on QuiltArt.com about copyright. Congress is debating the Orphan Works bill (there is an excellent article on this subject here) and the subject of Flickr.com came up.
As the U.S. military sets out to secure cities including Kandahar, it is relying far more heavily on Afghan forces than at any time in the past nine years, when the American mission focused mainly on defeating the Taliban in the countryside, rather than securing the population. But the Afghan forces are proving poorly equipped and sometimes unmotivated, breeding the same frustration U.S. troops felt in Iraq when they began building up security forces beset by corruption, sectarianism, political meddling and militia infiltration.. ...
Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis are now recognized as core features of Alzheimer’s disease (AD), and there is a general consensus that greater symptom severity is predictive of faster cognitive decline, loss of independence, and even shorter survival. Whether these symptoms result from the same pathogenic processes responsible for cognitive decline or have unique etiologies independent of AD-associated neurodegeneration is unclear. Many structural and metabolic features of the AD brain are associated with individual neuropsychiatric symptoms or symptom clusters. In addition, many genes have been identified and confirmed that are associated with symptom risk in a few cases. However, there are no single genes strongly predictive of individual neuropsychiatric syndromes, while functional and structural brain changes unique to specific symptoms may reflect variability in progression of the same pathological processes. Unfortunately, treatment
Background: To study the extent to which neuropsychiatric symptoms (NPS) influence the cognitive and functional decline in frontotemporal degeneration (FTD) and Alzheimers disease (AD).Methods: We assessed the progression of NPS and their influence on cognitive and functional progression in a group of FTD (n = 36) and AD patients (n = 47) at two different stages of the disease (2.5 years). A standardized scale was used to assess NPS-the Columbia University Scale for Psychopathology in Alzheimers Disease (CUSPAD)-which tracks different symptoms including depression, psychotic symptoms, as well as sleep and conduct problems. In addition, in a subsample of patients (AD n = 14 and FTD n = 14), we analyzed another group of NPS by using the Neuropsychiatric Inventory (NPI). Cognitive declines were tracked by using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE), while functionality was tracked by using the Lawton scale and the Barthel Index.Results: The presence of NPS
It is generally agreed, mortality and morbidity rates, in patients operated on for ruptured intracranial aneurysm, strictly depend upon the state at admission. Nevertheless, a precise definition of surgical mortality is still not available. Even the term morbidity still remains rather controversial for the lack of accurate evaluation scales. The wide range of parameters, affecting the composition of sample and outcome of patients, such as age, blood at CT scan and atherosclerosis at angiography, makes harder a correct statistical analysis of mortality and morbidity. Moreover, the gap between bleeding and admission, the management and choice of treatment, the selection of unicentric or multicentric studies, the level of the hospital introduce even more striking bias errors. Recent papers reported concrete improvements obtained by means of both aggressive therapeutical behaviour and adequate intensive care management. Among factors, producing improvement of the overall outcome, have to be also ...
Performance artist Marina Abramovic's piece Measuring the Magic of Mutual Gaze is both art installation and science experiment, in which volunteers
Neuropsychiatric symptoms are commonly related to interferon alpha treatment. The paper summarises the current knowledge about their aetiology, course
Mental disorders can be classified into panic attack, Anxiety, Stress, Eating disorder, Depression, Anorexia, Obesity and post traumatic disorder
It is not only possible to work with early onset Parkinsons disease, it is probable. Most people who were working prior to diagnosis continue to work for some period of time afterwards.. How long will I be able to work? This is usually the more difficult question to answer. The length of time each person continues working will depend on many different factors. Some will be related to the disease itself such as symptoms, medication side effects, or progression of the disease; others are likely to be environmental factors including the overall economy and your particular employer.. When it comes to Parkinsons Disease in the workplace, it can be helpful to think of symptoms as internal and external as motor symptoms and non-motor symptoms. External symptoms are those your employer, co-workers or clients may notice such as tremor, slowness, rigidity, facial mask, etc.and those that involve more internal processes such as fatigue, sleepiness, apathy or difficulty concentrating/multi-tasking. ...
Learn 200 innovative, problem-stopping strategies to prevent or stop social, emotional, behavioral, and K-12 classroom management problems like bad attitudes, cyberbullying, poor motivation, truancy, delinquency, work refusal, school failure, disrespect, defiance, depression, trauma and apathy. Plus, earn $45-$60 college credit and free clock hours from our live, online and on-site professional development courses.. ...
My moms only brother, my uncle, passed away unexpectedly in November of 2009. It was a devastating loss, as I have a very small family, and it was the first time I had lost someone close to me. It took a heavy emotional toll; because of the pain I felt, and because of the unimaginable sadness my mom and grandparents were enduring. I fell into a deep depression shortly thereafter, a combination of apathy, numbness and anger. About 8 months later, at the behest of my parents, I began to see a psychologist. After a few sessions of him getting to know my history, I was diagnosed with not only acute depression, but also cyclothymia, a less severe form of bipolar disorder. He suspected that I had lived several years of my early adulthood under a mild, persistent depression. I rejected that notion at the time, thinking it was just the way I am, but in hindsight Ive come to realize that he was right ...
Learn 200 innovative, problem-stopping strategies to prevent or stop social, emotional, behavioral, and K-12 classroom management problems like bad attitudes, cyberbullying, poor motivation, truancy, delinquency, work refusal, school failure, disrespect, defiance, depression, trauma and apathy. Plus, earn $45-$60 college credit and free clock hours from our live, online and on-site professional development courses.. ...
This mutation was identified in a Korean woman with AD and a family history of the disease (Kim et al., 2020). Her symptoms, starting at age 40, included memory impairment, visuospatial dysfunction, abulia, apathy, and depression. Moreover, shortly prior to death and three years after disease onset, the patient developed myoclonus and seizures. Her APOE genotype was APOE3/APOE3.. This variant was not found in the gnomAD database, nor in 500 Korean controls.. Neuropathology ...
It has anti-tumor, antiseptic, detoxifying, diuretic, antidepressant effects; helps with apathy, anxiety and has stimulating, as well as soothing properties. It attenuates headaches, stress, fatigue, induces relaxation. It is effective against overload of the entire organism, has an impact onto the balance of the body, supports and revives the condition to be able to withstand stress. It stimulates brain function, which helps in concentration. It supports the digestive tract, increases bowel movement and helps the body get rid of harmful toxins that occur in the metabolism. It also helps in constipation and insufficient digestion, increases urine production and eliminates excess water from the body. It can effectively help with tired and stiff muscles, especially during excessive physical activities. It promotes the immune system and fights free radicals, which are considered the cause of many diseases ...
Needle-like leaves and smells like pine is what this herb resembles. It has a powerful phytochemical called carnasol. What is great about it is its ability to detox cancer causing substances. Usually people add Rosemary in their soups, vegetable dishes and rice. Internally rosemary herb is used for depression, apathy, nervous exhaustion, headaches and migraines associated with nervous tension or feeling cold, poor circulation, and digestive problems associated with anxiety. Externally for rheumatism, arthritis, neuralgia, muscular injuries, wounds, dandruff, and scurf ...
By learning how to stimulate your own dopamine levels naturally, you wont have to feel depressed or suffer from anxiety, apathy, and fear.
Whos-Bored.com - Lets Make Politics F***ing Awesome!Whos-Bored.com is on a mission to break through the yawn barrier of British politics and turn apathy into action!Posted by Hands up whos...
Even if you have a CI process in place that runs all your tests and measures your code coverage, if you allow the build to stay broken, all of your work is for nothing. At the same time, breaking a build should not be a criminal offense. You want your team members to commit their changes frequently. When they do this its okay to have a build fail. You dont want developer to be overly cautious when committing, fearing a broken build. What you dont want is to let a build stay broken. If you leave a build broken for a long period of time, it is a symptom of apathy about keeping the code base at a high level of quality. You should also never commit changes to a broken build. You dont know what impact your changes will have on a systems that is not passing all of its tests. Also remember that the team has ownership of the code. Anyone can fix the build (that includes you), it doesnt have the person who broke the test.. There are lots of ways to enforce this. The easiest way is that tools like ...
Most of the weight of your dehydrated brain would come from fats also known as lipids. In the remaining brain matter, you would find proteins and amino acids, traces of micronutrient and glucose. The brain is, of course, more than just the sum of its nutritional parts, but each component does have a distinct impact on functioning, development, mood and energy. So that post-lunch apathy or late-night alertness you might be feeling that is simply the effects of food on your brain. Of the facts in your brain, the superstars are Omega 3 and 6. These fatty acids which have been linked to preventing degenerative brain conditions must come from our diets. So eating omega rich food like nuts, seeds and fatty fish is crucial to the creation and maintenance of cell membranes.. While omegas are good fats for your brain, long term consumption of other fats, such as tans and saturated fats may compromise brain health. Meanwhile, protein and amino acids the building block nutrients of growth and development ...
As people get older, they experience changes in their foot morphology. If they do not change their shoe size along with these transformations, older people-most of whom choose the wrong shoes-suffer, among other things, anxiety, apathy, loss of balance and falls, according to a study by the University of A Coruña.
As educators, we pit ourselves every day against the most savage of enemies: ignorance, anti-intellectualism, apathy, prejudice, meanness. We can no more unplug in our struggle against these foes than our forebears should have thrown away their slates and books because a few students scribbled profanities or a few authors wrote hate and lies.
The traditional American Indian dieting appears sanitary. Populate too referred to it as coco laurel wreath sugar, or coconut meat bloom nectar in its limpid shape. In this article, we look at the mass creditworthy for this groundbreaking ceremony diabetes discourse. Though everyone experiences apathy differently, thither are a few symptoms that are considered to be hallmarks of the circumstance. Many of these do non ingest celiac disease. Laugh helps to work up relationships and, when animation in a mathematical group on the savannah, soldering with success toilet be the divergence between life and destruction. We besides bet at former conceivable causes of tooth sensitiveness. Spell that is a time that might good absurd, or even nightmarish to some, xenotransplantation is a credible scientific discipline involving the figure out of ahead scientists and glorious organizations alike the NHLBI and the Mayonnaise Clinic, as good as bombastic buck private medicine firms such as Combined ...
Yet, an analysis of election results by The Pew Research Center reveals that voters 65 and older preferred the Republican candidate 53-45 percent. According to the Gallup Poll, congressional approval rating in 2016 averaged 17 percent. In the face of a national health crisis, Congress argued for nearly seven months over a Planned Parenthood defunding rider before agreeing to allocate $1.1 billion to help fight the spread and effects of the Zika virus. According to the Organization for Economic Cooperation and Development, the United States ranks 31st among the 35 most advanced democratic countries in terms of voter participation. Political apathy, therefore, helped, to elect a president intent upon destroying the air that we all breathe in the name of economic progress.
EMPLOYED TO SERVEs trajectory to-date has been explosive. Two bedroom-crafted EPs (released by Jay Randall from Agoraphobic Nosebleed on Grindcore Karaoke) preceded last years full-band EP, Change Nothing, Regret Everything which also marked the beginning of their relationship with Holy Roar Records. Embroiling a DIY approach and work ethic, they have now played 100 gigs throughout Europe, in just over a year. Recorded and mixed by Lewis Johns (Gnarwolves, Funeral For A Friend) and mastered by Brad Boatright (Converge, Integrity) this collection of tracks was placed in safe hands. This confident, cohesive and colossal sounding album of technical hardcore features the recurring theme of self-worth and apathy for life, a theme that was present in their previous release. It also focuses on tragic personalities encountered in day-to-day life. They ve honed their shards of mosh-detonation, such as the (early) Norma Jean/Everytime I Die stylings of Threads and No Ones Perfect..., whilst ...
In Ronald Reagans 1989 farewell speech he inspired the youth in America to dream of change and pursue active leadership for the good of America. All great change in America begins at the dinner table, Reagan told America. And he was right. Yet as a college student, I am aware of how many of my contemporaries across this nation see little reason to devout themselves in the world of politics. Millions of college students around the country would rather stay in their comfortable safe havens of youthful apathy then dare to engage the complex political world surrounding them. Many young ...
Green, Apathy, and Buckwild come up with fresh, funky ideas, R.A. responds with excellence, and sometimes a J-Zone-sized sense ... Apathy)". 2dopeboyz. 2013-02-20. Retrieved 2013-09-16. CS1 maint: discouraged parameter (link) "R.A. The Rugged Man: The ... The album's production was handled by Buckwild, Ayatollah, Apathy and Marco Polo among others. The first single from the album ... "The People's Champ", produced by Apathy, was released on February 20, 2013. On April 9, 2013, the music video was released for ...
"Dive Medicine, Chapter 1 (Instrumental Project) by Apathy on Apple Music". iTunes. "Get Rich or Get Recalled by Fredo on Apple ... ". "Perestroika , Apathy". "The Big Brother by DJ Kay Slay on Apple Music". iTunes. "Gorilla Warfare by Gorilla Zoe on Apple ...
Apathy). "Martha Moxley (R.I.P.)". Genius Lyrics. Archived from the original on July 26, 2019. Retrieved July 26, 2019. The ... Apathy) (July 26, 2019). "Martha Moxley (R.I.P.)". Genius Lyrics (lyrics). Archived from the original on July 26, 2019. ... In 2014, Connecticut-born rapper Apathy released a song entitled "Martha Moxley (Rest in Peace)" featuring a sample from George ...
"Apathy synopsis". Irish Metal Archives. Retrieved 25 March 2011. CS1 maint: discouraged parameter (link) "Apathy "Lack of ... The name Creation's Tears was the title of an Apathy song from their 1995 album entitled Inertia. Joe Gillespie guitars and ... A different version of the same track (written by Reynolds) appeared on Apathy's Inertia album (1995) but featured Laura ... "Ref to the "original" version of the song "Creation's Tears" from Apathy - Inertia". Creation's Tears. Archived from the ...
"Electors' Apathy". The Sydney Morning Herald. National Library of Australia. 16 December 1935. p. 12. Retrieved 25 March 2013 ...
... apathy etc. De Sanctis, however, understands that the catatonia of a 3-year-old girl cannot have the same pathogenesis as ...
Fitzgerald, Mary (30 September 2010). "Ireland's apathy". The Guardian. London. As soon as Ireland's finance minister Brian ...
CS1 maint: discouraged parameter (link) Banks, Adam (September 20, 2010). "Athletic apathy". McGill Daily. Retrieved January 19 ...
Sajner, Josef (1970). "Stephan Apathy". Dictionary of Scientific Biography. 1. New York: Charles Scribner's Sons. pp. 176-177. ...
"Timeshares - Bearable (re-issue) (Dead Broke Rekerds, 2016)". Apathy & Exhaustion. January 31, 2017. Retrieved May 16, 2019. " ...
Horwitz, Jeremy (8 July 2002). "Mortal Apathy?". The New York Times. Archived from the original on 2013-10-03. Retrieved 15 ...
"; "Ode to Apathy"; "Ode to Duel" "Laura Maria" [Mary Robinson], "Ainsi va le Monde, A Poem inscribed to Robert Merry"; "Ode to ...
"Alternatives to Apathy". The Saturday Review. pp. 27-32. ISSN 0036-4983. Davids, Leo (1970). "Rev. of People or Personnel and ...
They are most noted for their 2020 album Glory, Glory! Apathy Took Helm!, which received a Juno Award nomination for Heavy ...
"Pierre Lapointe". Apathy is Boring. Archived from the original on 26 May 2015. Retrieved 4 May 2015. "Pierre Lapointe : "La ...
"Honkey Kong - Apathy > Overview". AllMusic. Rovi Corporation. Retrieved August 26, 2012. "The Mushroom Cloud Effect - Adil Omar ...
"Apathy" Scoe 00. "Thank You (Remix)" (featuring Kendrick Lamar and Slim the Mobster) Bambu - One Rifle Per Family 13. "Boom" ...
Apathy, S (1896). Die Mikrotechnik der thierischen Morphologie. Braunschweig. "wholemount - Wiktionary". en.wiktionary.org. ...
"Apathy and Exhaustion". Allmusic. Retrieved 2010-01-19. "Apathy and Exhaustion". Fat Wreck Chords. Retrieved 2010-01-19. Spano ... This was followed by the full-length album Apathy and Exhaustion, released in 2002. The album spawned the band's second music ...
"Apathy Eastern Philosophy". exclaim.ca. "Apathy - Eastern Philosophy - IGN" - via www.ign.com. "RapReviews.com Feature for ... Eastern Philosophy is the first official album by rapper Apathy. After years of deals in limbo, Apathy was finally able to ... 8 Apathy - track 7, 12 DJ Cheapshot - track 8 Exact Beats - track 11 8th & Vertygo - track 13 Executive Producer: Apathy ... www.amazon.com/Eastern-Philosophy-Apathy/dp/B000BJNTTO HAMAD, MICHAEL. "DJ ChumZilla Debuts New Album 'Get Off The Earth' On ...
"Deplores Voter Apathy; Miss Maude Wetmore Sees Party Government in Danger". The New York Times. December 14, 1927. p. 14 - via ...
"Apathy for Beginners". Visit Wagga. Archived from the original on 15 July 2019. Retrieved 15 July 2019.. ... There is also an Australian group who performs, named "Apathy for Beginners" Psychosomatic illness Brink, Susan. "In Sweden, ... apathy, non-communication, and loss of bodily functions. There are also signs of severe long-term stress which are worsened by ...
Alisoglu, Scott (August 15, 2015). "Dope - American Apathy". Blabbermouth.net. Retrieved April 9, 2018. "Goldrush - Ozona". ...
Horwitz, Jeremy (July 8, 2002). "Technology: Mortal Apathy?". The New York Times. Retrieved March 4, 2012. History of Computing ...
"Sponsors". Apathy is Boring. 2004-01-04. Archived from the original on 2014-03-28. Retrieved 2014-03-18. "Human Library a ... Apathy is Boring, and the Atwater Library in Quebec. On the 4th anniversary of the Quebec Mosque Shooting, Inspirit Foundation ...
Four days later, Apathy, through his YouTube account, released the first single for Killmatic titled "Demigodz Is Back". On May ... On January 14, 2013, Apathy confirmed that Killmatic would be released on March 5. Along with that, he confirmed the official ... It featured all members including Celph Titled, Apathy, Motive, Blacastan, Esoteric and Ryu. In Death Reborn, Army of the ... "Apathy - Timeline Photos". Facebook. Retrieved 2014-08-10. "Demigodz - Demigodz Is Back - KILLmatic *OFFICIAL VIDEO*". YouTube ...
"Death by apathy". www.telegraphindia.com. May 16, 2019 "'It was a full moon night and the tides were at their peak...'". www. ...
CS1 maint: discouraged parameter (link) Partos, Gabriel (14 April 2003). "Hungary's EU apathy". BBC News. BBC. Retrieved 23 ...
CS1 maint: discouraged parameter (link) Chadband, Ian (26 November 2004). "Apathy follows anarchy". Retrieved 14 January 2010. ...
p. 1. Lee, Vivian (11 June 1978). "Lamma-apathy island". South China Morning Post. p. 6. Dr WK Chan (2008), Chapter 3, Forty ...
"Apathy Matters - Apathy and Depression: Psychiatry may not care about apathy, but that doesnt mean you shouldnt Archived 20 ... The Dimensional Apathy Scale (DAS) is a multidimensional apathy instrument for measuring subtypes of apathy in different ... As a response, apathy is a way to forget about these negative feelings.[citation needed] This type of common apathy is usually ... The cure for apathy is comprehension." Apathy is a normal way for humans to cope with stress. Being able to "shrug off" ...
Army of the Pharaohs discography Get Busy Committee discography "Perestroika by Apathy & O.C. on Apple Music". iTunes. "Apathy ... The discography of Apathy, an underground rapper from Connecticut, USA. He released several studio albums, EPs and mixtapes. ...
Although not a well-established psychological syndrome among educators, assessment apathy can be serious. For example, consider ...
... which researchers say is the first evidence of a biological basis for apathy. ... Apathy in older adults linked to increased brain shrinkage Older people who have apathy - a lack of interest or emotion - are ... Though apathy is traditionally viewed as an attitude or outlook, the neuroscientists say their results suggest it is actually ... Does reading the rest of this article feel like too much work? If so, your apathy may be down to specific brain differences, ...
Ive been involved with my sweety-pie since she was 99, although not directly in her day-to-day rehabilitation until she was given up by a professional rehab center about 19 months ago. Her visiting nurse showed up. She was in a room alone, tied to the bed with no wheelchair and only a 25 watt light in the room. She was only being fed warm ensure. The aides would go to another part of the house and watch television all day. The nurse told me Shes 100 years old. She cant possibly benefit from visual stimulation. Let her die in dignity. It was at that point I said to this creature R.N. things I cant repeat on this board. The aides were criminals who stole her jewelry and wedding ring and who I witnessed forcing scalding soup into her mouth. Yup. I fired that one. And they would show up with colds and deliberately cough in her face. A witnessed event. And they threw out her favorite dolls. And tied her water bottle to the bedrail just out of her reach. If this was 1814 I would have called out ...
... predominantly minority schools-soon become disillusioned and discouraged in the face of widespread student apathy. ...
... Roberta Semprini,1 Adele Lubrano,1 Giulia Misaggi,1 and Alessandro Martorana1,2 ... R. S. Marin, B. S. Fogel, J. Hawkins, J. Duffy, and B. Krupp, "Apathy: a treatable syndrome," Journal of Neuropsychiatry and ... C. U. Onyike, J. M. E. Sheppard, J. T. Tschanz et al., "Epidemiology of apathy in older adults: the cache county study," ... R. Levy and B. Dubois, "Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits," Cerebral Cortex, ...
Learn about the possible causes of apathy, depression and anxiety and how these psychological conditions might affect the ... Apathy. One of the reasons that people with dementia are thought to develop apathy is damage to the brains frontal lobes. ... Experiencing apathy, and causes of depression and anxiety. Many of the things that can cause people to feel depressed can also ... A person experiencing apathy alone will not have symptoms of low mood, more a feeling of being without energy or spark. ...
Ukraine has entered the last week before the January 17 presidential election with many disappointed voters and attempts to alter the vote at local election commissions.
Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T ... Apathy and cortical atrophy in Alzheimers disease.. Tunnard C1, Whitehead D, Hurt C, Wahlund LO, Mecocci P, Tsolaki M, Vellas ... Apathy is mediated by frontocortical structures but this is specific to the left hemisphere at least for patients in the mild ... We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had ...
The Cost Of Apathy. By Roger Anghis,2017-08-06T01:32:32-04:00August 6th, 2017, ... What we are seeing not just is Washington, D.C. but across the nation is the results of fifty plus years of apathy of the ... Will it eventually happen? Im afraid yes simply because of apathy. We no longer teach the greatness of America and unless the ...
As the figures in the chart show, only 34 per cent of YouGovs respondents said they would like to be wed in a church or some other place of religious worship - a synagogue, mosque or temple. Nearly double that proportion, 63 per cent, would prefer not to be married in a place of worship at all (23 per cent) or else shrugged their shoulders and said indifferently that they "would not mind one way or the other" (40 per cent).. ...
Home » Magazine » National » No Cure For Encephalo-Apathy No Cure For Encephalo-Apathy. True, remedy is non-existent for the ... Dr R.N. Singh August 17, 2017 00:00 IST No Cure For Encephalo-Apathy outlookindia.com ...
... Share this:. *Click to share on Facebook (Opens in new window) ...
Political Apathy or Energy?. By Katie Ash on July 9, 2008 11:50 AM ...
The link between apathy and depression as well as apathy and impulsivity was explored in two contributions. D. Ahearn et al. ... The papers in this issue encompass a broad spectrum of clinical aspects of apathy with a clear overarching theme of apathy as ... the overlap between apathy and depression, and the application of new technologies in the management of apathy in the nursing ... the degree of overlap between depression and apathy was dependent on the method of assessment of apathy. The assessment and ...
Lettin Apathy get on the mic Thats like unleashing a f**king atom... ... Apathy Just Begun lyrics & video : [Funkmaster flex sample] [Celph Titled] Yo what the f**k are yall thinkin ... APATHY. Just Begun Lyrics. [Funkmaster flex sample]. [Celph Titled]. Yo what the f**k are yall thinkin. Lettin Apathy get on ... Yo Apathy rip the spines outta these mutherf**kers. [Apathy]. Im gonna spit an incredible verse. Your headll reverse and ...
A prime example of apathy and ignorance was to be seen at an open forum held in Battlement Mesa last Saturday with Rep. Bob ... Apathy is what will eventually have us enslaved.. What would our state representative have taken away from this puny gathering ... A prime example of apathy and ignorance was to be seen at an open forum held in Battlement Mesa last Saturday with Rep. Bob ... Letter: Apathy and ignorance. Letter To The Editor Letter-to-the-editor , ...
"Weve killed despair across the country and weve killed apathy.". The Occupy Movement has spread across the country and around ... Michael Moore joined the protesters in Oakland this week to congratulate them on successfully killing apathy in America. ...
A review of the literature on apathy, hypothalamic-pituitary-end organ axis dysfunction, and treatment for apathy syndrome is ... A review of the literature on apathy, hypothalamic-pituitary-end organ axis dysfunction, and treatment for apathy syndrome is ... Apathy Syndrome and Pituitary microadenoma?? Blue727 I just found this article from The Journal of Neuropsychiatry & Clinical ... I hope that more doctors now are thinking of hormone dysfunction as a cause of anxiety and apathy. If only they would refer ...
Findings from a recent study suggest that older adults who develop severe apathy over time may be at a higher risk of also ... "Apathy can be very distressing for family members, when people no longer want to get together with family or friends or dont ... Apathy could be an indicator of dementia, study finds. Researchers say losing interest in activities that are usually ... "In fact, we believe that apathy may be a very early sign of dementia and it can be evaluated with a brief questionnaire." ...
Apathy. Published by the European Parkinsons Disease Association (EPDA), February 2018. Apathy is a symptom of Parkinsons. ... Apathy. Published by the Parkinsons Foundation. This short webpage distinguishes between depression and apathy. It includes ... The conversation distinguishes apathy from depression. The focus is on how apathy affects both the person with PD and those who ... It provides three rating scales to help diagnose apathy in Parkinsons, medication and counseling options to treat apathy, ...
Why Apathy in Alzheimers Matters. Am J Psychiatry. 2018 Feb 01;175(2):99-100 Authors: Sultzer DL PMID: 29385833 [PubMed - in ... Why Apathy in Alzheimers Matters. Am J Psychiatry. 2018 Feb 01;175(2):99-100 Authors: Sultzer DL PMID: 29385833 [PubMed - in ...
Apathy towards poachers widespread in worlds marine protected areas A new study has found that nearly half of fishers from ... Apathy towards poachers widespread in worlds marine protected areas. ARC Centre of Excellence in Coral Reef Studies ... "The bad news is that apathy towards poaching in marine protected areas is widespread," said co-author Dr Michele Barnes, "but ...
Its not true that no one worries about terrorists attacking chemical plants, its just that our politics seem to leave us unable to deal with the threat.. Toxins such as ammonia, chlorine, propane and flammable mixtures are constantly being produced or stored in the United States as a result of legitimate industrial processes. Chlorine gas is particularly toxic; in addition to bombing a plant, someone could hijack a chlorine truck or blow up a railcar. Phosgene is even more dangerous. According to the Environmental Protection Agency, there are 7,728 chemical plants in the United States where an act of sabotage - or an accident - could threaten more than 1,000 people. Of those, 106 facilities could threaten more than a million people.. The problem of securing chemical plants against terrorism - or even accidents - is actually simple once you understand the underlying economics. Normally, we leave the security of something up to its owner. The basic idea is that the owner of each chemical plant ...
... By Joe ConchaOct 23rd, 2014, 2:58 pm ... And programs like Meet the Press and The View are suffering from familiarity breeding contempt (and apathy) as a result. ...
NGT reaches fever pitch on civic apathy. TNN , Updated: Sep 22, 2016, 07:51 IST ...
the frequency of apathy as assessed by the NPI is Frequently or Often AND the severity of apathy as assessed by the NPI is ... Clinically significant apathy for at least four weeks for which either. *the frequency of apathy as assessed by the ... Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months ... Apathy in Dementia Methylphenidate Trial 2 (ADMET2). The safety and scientific validity of this study is the responsibility of ...
... into an ambulance at Bongaon in West Bengal went viral and the apathy of the people seen around them has come in for flak. ... The mans wife has blamed the sub-divisional hospital for negligence and apathy for her husbands death. ... into an ambulance at Bongaon in West Bengal went viral and the apathy of the people seen around them has come in for flak. ...
Apathy Evaluation Scale (AES) [ Time Frame: baseline to 6 weeks ]. Change in score of Apathy Evaluation Scale from baseline to ... Clinically significant apathy for at least four weeks for which either 1) the frequency of apathy as assessed by the ... Apathy in Dementia Methylphenidate Trial (ADMET) (ADMET). The safety and scientific validity of this study is the ... Apathy Alzheimers Disease Drug: Methylphenidate Drug: placebo Other: Psychosocial intervention Phase 2 ...
  • Political Apathy or Energy? (edweek.org)
  • As South Africans head to the polls to vote in the national and provincial elections, we take a look back at Kgodisho Mowa's work, which seeks to counter the political apathy amongst the country's youth. (designindaba.com)
  • Mowa hopes his designs will act as a trigger against political apathy among young people. (designindaba.com)
  • Brexit factor has helped stir us from political apathy. (edp24.co.uk)
  • What's The Antidote To Political Apathy? (ualrpublicradio.org)
  • A review of the literature on apathy, hypothalamic-pituitary-end organ axis dysfunction, and treatment for apathy syndrome is included. (medhelp.org)
  • To HAVE YOU: Weed tas a treatment for Apathy? (cnn.com)
  • The clinical signs grouped under the concept of apathy are a common feature of prefrontal and basal ganglia lesions or dysfunctions and can therefore help to improve our understanding of the functional anatomy of the prefrontal-basal ganglia system. (nih.gov)
  • The aim of this study was to examine the concept of apathy as it is currently used in neurology and psychiatry, by review of the literature and conceptual analysis. (bmj.com)
  • The contemporary concept of apathy could not be more different than the Stoic. (bmj.com)
  • This short webpage provides specific tips to increase participation in needed and desired activities in spite of the symptoms of apathy. (stanford.edu)
  • Other symptoms of apathy: The sharp limitation of social contacts, everyday activities and … You can also try these tips to help you or a loved one manage apathy: Alzheimer's Society: "Apathy and dementia. (bancuriok.com)
  • If you have a family member with PD, it is important that you notice the following symptoms of apathy: Then you probably have apathy. (bancuriok.com)
  • In a new study by ESM Eurelings and colleague in the journal International Psychogeriatrics , the inflammatory marker C-reactive protein differentiated between older people with symptoms of apathy versus symptoms of depression. (bipolarnews.org)
  • Higher levels of C-reactive protein were found in those with symptoms of apathy. (bipolarnews.org)
  • There is discussion about whether an emotional dimension should form part of the definition of apathy. (bmj.com)
  • Current psychiatric classification systems do not provide a definition of apathy. (bmj.com)
  • In addition, critical questions regarding the phenomenology of apathy and the syndromal validity of this construct, as well as the relationship between apathy and similar concepts, such as abulia, the autoactivation deficit, athymormia, the negative syndrome and psychic akinesia, still remain unanswered. (bmj.com)
  • In our study, series of exploratory Spearman rho correlation confirmed the significant relationship between apathy and caregiver burden with and without depression. (ovid.com)
  • Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimer's disease (AD), associated with greater functional decline and caregiver distress. (nih.gov)
  • We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. (nih.gov)
  • Now, a new study conducted by researchers from the American Academy of Neurology has discovered a new symptom that could increase consumers' risk of developing Alzheimer's: apathy. (consumeraffairs.com)
  • Apathy is a symptom of Parkinson's. (stanford.edu)
  • Firsthand accounts from those coping with apathy as a symptom of PD demonstrate that lifestyle changes and support go a long way toward maintaining a good quality of life despite feelings of apathy. (stanford.edu)
  • This post in the Foxfeed Blog explains apathy is a non-motor symptom of Parkinson's disease, the symptoms, potential consequences, diagnosis, behavioral adjustments to help live with apathy and medication options. (stanford.edu)
  • There is however no consensus as to whether apathy should be considered a symptom of major neuropsychiatric disorders, or as a syndrome in its own right. (bmj.com)
  • Although there are symptom overlaps, apathy and depression are two separate and distinct diagnoses. (uhhospitals.org)
  • He went on to say that the charity's own research had found apathy to be a common symptom, while understanding why people with the condition may be apathetic may help carers. (barchester.com)
  • Apathy occurs frequently in neuropsychiatric disorders both as a symptom of other syndromes and as a syndrome per se. (bancuriok.com)
  • Etiologies included non-Alzheimer's frontal lobe dementia, cerebral infarction, intracranial hemorrhage, alcoholism, and … Both the symptom and the syndrome of apathy are of conceptual interest because they signify loss of motivation. (bancuriok.com)
  • It is clear from the current literature that apathy is a common symptom in both AD & aMCI and has significantly adverse consequence to both the patients and the caregivers. (ovid.com)
  • found that in Parkinson's disease, apathy and impulsivity might overlap and that specific phenomenological profiles within the behavioural syndromes were associated with particular clinical phenotypes. (hindawi.com)
  • Apathy and Parkinson's Disease, Does it Really Matter? (stanford.edu)
  • This short article emphasizes Parkinson's disease is no longer just a movement disorder, but symptoms, like apathy, require active management. (stanford.edu)
  • Fatigue and apathy are common non-motor symptoms in Parkinson's Disease (PD). (asaging.org)
  • Likewise, apathy occurring in Parkinson's disease could be interpreted as secondary to the loss of spatial and temporal focalization of the signals transferred to the frontal cortex. (nih.gov)
  • In Parkinson's disease, reduced pupillary modulation by incentives was predictive of apathy severity, and independent of motor impairment and autonomic dysfunction as assessed using overnight heart rate variability measures. (nih.gov)
  • Apathy is also a feature of other nervous system disorders like Parkinson's disease as well as mental health disorders like depression (which is also common in Alzheimer's). (alzinfo.org)
  • A new scientific study suggests that apathy shown by a person with Parkinson's disease is a sign that the condition is worsening. (barchester.com)
  • Starkstein SE (2012) Apathy in Parkinson's disease: diagnostic and etiological dilemmas. (springer.com)
  • Higuchi MA, Tsuboi Y, Inoue T, Fukuyama K, Abe H, Baba Y, Yamada T (2015) Predictors of the emergence of apathy after bilateral stimulation of the subthalamic nucleus in patients with Parkinson's disease. (springer.com)
  • Drapier D, Drapier S, Sauleau P, Haegelen C, Raoul S, Biseul I et al (2006) Does subthalamic nucleus stimulation induce apathy in Parkinson's disease? (springer.com)
  • Czernecki V, Schüpbach M, Yaici S, Lévy R, Bardinet E, Yelnik J et al (2008) Apathy following subthalamic stimulation in Parkinson's disease: a dopamine responsive syndrome. (springer.com)
  • However, they add that their findings do not account for apathy in everyone, but rather, they provide more information about brain processes involved in "normal motivation. (medicalnewstoday.com)
  • Apathy describes a lack of interest, enthusiasm or motivation. (stanford.edu)
  • Apathy is a feeling of indifference or lack of interest or motivation in activities. (stanford.edu)
  • Apathy causes a general lack of motivation and interest, as well as a dampening of emotional expression. (michaeljfox.org)
  • The past few decades have seen growing interest in the neuropsychiatric syndrome of apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed behaviour. (bmj.com)
  • This description resonates with much of the phenotype of apathy, a neuropsychiatric syndrome conceptualised as a loss of motivation that manifests in reduced goal-directed behaviour 1 2 -see box 1 for key definitions. (bmj.com)
  • Apathy is a lack of motivation towards goal directed behaviours and has been reported as occurring in up to 50 per cent of people living with motor neurone disease (MND). (uea.ac.uk)
  • Our previous research showed Initiation apathy (a lack of motivation for generation of thoughts) is characteristic in MND and associates with performance on certain neuropsychological tasks. (uea.ac.uk)
  • This research is of a cross-sectional design looking at associates of apathy subtypes in people living with MND and a further longitudinal design, with people with MND and their families being asked to take part in four repeat interviews every three months for a year exploring any changes in motivation, behaviour, cognition, quality of life and well-being. (uea.ac.uk)
  • One of the most common is apathy, or loss of motivation, and the condition seems to have a biological basis. (alzinfo.org)
  • Those with mild cognitive impairment, a form of serious memory loss that sometimes precedes Alzheimer's, are also more likely to exhibit the loss of motivation that occurs with apathy. (alzinfo.org)
  • Those affected by apathy show a lack of motivation and often withdraw from social and other activities. (alzinfo.org)
  • Apathy is mostly defined as a disorder of motivation, and operationalised as diminished goal oriented behaviour and cognition. (bmj.com)
  • While many people associate apathy with a lack of passion or motivation, it is technically defined as the absence of emotion. (addicted2success.com)
  • If you know you are dealing with apathy, it is time to make a change and it is time to turn that apathy into positive motivation. (addicted2success.com)
  • If you want to turn your apathy into motivation to succeed, the number one thing you can do is to stop complaining. (addicted2success.com)
  • How will you turn apathy to positive motivation? (addicted2success.com)
  • Concomitantly, there was an improvement in the patient's clinical state, with reduced apathy, greater motivation and increased social interactions. (pubmedcentralcanada.ca)
  • The profound lack of motivation seen in patients with significant apathy limits their ability to carry out the simplest activities of daily living, thus increasing the demands made on caregivers. (uhhospitals.org)
  • The growing widespread concern over public apathy, rising health concerns, and the apparent stupidity of our school children keeps mounting. (just-think-it.com)
  • ADMET 2 is designed to examine the efficacy and safety of methylphenidate as treatment for clinically significant apathy in AD participants. (clinicaltrials.gov)
  • ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimer's dementia. (clinicaltrials.gov)
  • ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimer's disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. (clinicaltrials.gov)
  • ADMET will enroll 60 patients with Alzheimer's disease (AD) and significant apathy from outpatient, nursing home, and assisted living facilities along with their primary caregiver. (clinicaltrials.gov)
  • Two hundred patients with clinically significant apathy will be recruited and each will undergo a series of physical, cognitive and neuropsychiatric tests at the beginning of the study and at monthly follow-up visits. (uhhospitals.org)
  • How to Deal With Apathy at the Workplace" accessed March 22, 2018. (chron.com)
  • Teachers start the school year with high hopes, but many-especially those in low-income, predominantly minority schools-soon become disillusioned and discouraged in the face of widespread student apathy. (ascd.org)
  • The bad news is that apathy towards poaching in marine protected areas is widespread," said co-author Dr Michele Barnes, "but the good news is that there are already many tools and programs to encourage citizens to report poaching and other types of crimes. (eurekalert.org)
  • Understanding the mechanisms underlying apathy is therefore of urgent concern but this has proven difficult because widespread brain changes in neurodegenerative diseases make interpretation difficult and there is no good animal model. (pubmedcentralcanada.ca)
  • Apathy is widespread in mild forms in many people. (pubmedcentralcanada.ca)
  • Despite this, for a multitude of reasons, vaccination apathy is a widespread global issue and a key barrier to protecting the community against infectious disease. (presseportal.de)
  • These findings suggest that reward insensitivity may be a contributory mechanism to apathy and provide potential new clinical measures for improved diagnosis and monitoring of apathy.media-1vid110.1093/brain/aww188_video_abstractaww188_video_abstract. (nih.gov)
  • The specific topics represented by the papers range from an exploration of the phenomenology of apathy and the manifestation of apathy in different neurodegenerative conditions, the overlap between apathy and depression, and the application of new technologies in the management of apathy in the nursing home settings. (hindawi.com)
  • Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) is a Phase III, placebo-controlled, masked, 6 month, multi-center randomized clinical trial sponsored by National Institutes of Aging involving 200 participants with Alzheimer's disease (AD). (clinicaltrials.gov)
  • The Apathy in Dementia Methylphenidate Trial (ADMET), funded by the National Institute of Aging, is a Phase II, placebo-controlled, masked, 3-center randomized clinical trial. (clinicaltrials.gov)
  • Although many patients with pathological apathy also suffer from depression, several studies have shown that the two syndromes are dissociable: apathy can occur independently of depression and vice versa. (wikipedia.org)
  • The findings also shed light on how patients with "pathological conditions of extreme apathy" may be helped. (medicalnewstoday.com)
  • Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and ventrolateral frontal regions, than those without apathy symptoms. (nih.gov)
  • Apathy is mediated by frontocortical structures but this is specific to the left hemisphere at least for patients in the mild to moderate stages of AD. (nih.gov)
  • P. Njomboro and S. Deb found that in a sample of patients with acquired brain injury, the degree of overlap between depression and apathy was dependent on the method of assessment of apathy. (hindawi.com)
  • When the diagnosis of apathy syndrome was considered and treatment implemented, the patients' condition improved. (medhelp.org)
  • Discuss how nurses can recognize and intervene with patients suffering fatigue and apathy. (asaging.org)
  • However, the effect of apathy subtypes and how they translate into functioning in everyday life and wellbeing in MND, for both the patients and their families, are seldom explored. (uea.ac.uk)
  • Furthermore, determining to what extent apathy subtypes are associated with quality of life will help inform the design of behavioural interventions using domains where patients do not have motivational difficulties, linking to the MND research program and the development of the MiND Toolkit project at the University of East Anglia and the Clinical Audit Research Evaluation-MND (CARE-MND) platform at the University of Edinburgh. (uea.ac.uk)
  • Dr. Marc Dalton of Dalton Psychiatry in Washington says he sees apathy in a number of his elderly patients. (cnn.com)
  • Apathy reduces the quality of life for patients with dementia and increases the workload for caregivers. (alzinfo.org)
  • M. Jonsson, A. Edman, K. Lind, et al: "Apathy is a Prominent Neuropsychiatric Feature of Radiological White-matter Changes in Patients with Dementia. (alzinfo.org)
  • There are several valid and reliable scales to measure the severity of apathy in patients with psychiatric and neurological disorders. (bmj.com)
  • In spite of a lack of a proper definition, "apathy" is increasingly diagnosed in patients with neurological and psychiatric conditions. (bmj.com)
  • In summary, a pICA decomposition suggested BD patients showed distinct mood and apathy profiles differing from the original PANSS subscales, relating to distinct brain structural networks. (uio.no)
  • Previous morphology studies have demonstrated that apathy in patients with schizophrenia is associated with reduced frontal grey matter (GM). (ovid.com)
  • We replicated previous associations between reduced frontal GM and apathy in patients with schizophrenia. (ovid.com)
  • Currently, there are no proven treatments available for patients who display significant signs of apathy associated with Alzheimer's disease. (uhhospitals.org)
  • It is also important to keep in mind that patients with dementia or PD who also have apathy can cause great exhaustion and stress in the people who must take care of them, causing the famous caregiver syndrome. (bancuriok.com)
  • In summary, there is a big difference between what people commonly call apathy and true apathy, which usually occurs in patients with other metal diseases. (bancuriok.com)
  • Further correlational analyses was carried out after removing patients with depression (HADS depression scores>or=to 8) .Forward stepwise linear multiple regressions identified significant predictors of apathy. (ovid.com)
  • Actively screening, monitoring and managing apathy in clinical practise would improve the prognosis and quality of life of these patients. (ovid.com)
  • In this study, we describe three PD patients with STN DBS-related apathy who experienced a fast resolution of symptoms after switching stimulation from ventral to dorsal STN stimulation. (springer.com)
  • In this study we will investigate the effectiveness of several treatment options including transcranial Direct-Current Stimulation (tDCS), repetitive Transcranial Magnetic Stimulation (rTMS), and rTMS in combination with Behavioural Activation Therapy (BAT) to treat apathy in schizophrenia patients. (rgoc.nl)
  • Apathy due to the disruption of 'emotional-affective' processing refers to the inability to establish the necessary linkage between emotional-affective signals and the ongoing or forthcoming behavior. (nih.gov)
  • Apathy due to the disruption of 'cognitive' processing refers to difficulties in elaborating the plan of actions necessary for the ongoing or forthcoming behavior. (nih.gov)
  • The neural mechanisms of apathy are postulated to involve the brainstem and forebrain circuits that regulate goal-directed behavior. (glutenfreeworks.com)
  • The prevailing attitudes of overconfidence and apathy may be to blame for what is a notable discrepancy among survey respondents in understanding what responsible security behavior looks like and actually engaging in that behavior. (securitymagazine.com)
  • Apathy affects interpersonal behavior with pervasive negative consequences," says Alan Lerner, MD , Director of the Brain Health & Memory Center at UH Cleveland Medical Center . (uhhospitals.org)
  • Background: Apathy, the major manifestation of impaired goal-directed behavior (GDB), is the most common neuropsychiatric syndrome associated with behavioral variant frontotemporal degeneration (bv FTD). (elsevier.com)
  • Research published in the Journal of Neurology, Neurosurgery and Psychiatry suggest that apathy can be caused by changes in the brain resulting from the condition, Parkinson's UK reports. (barchester.com)
  • One of the reasons that people with dementia are thought to develop apathy is damage to the brain's frontal lobes. (alzheimers.org.uk)
  • Apathy is also consistently associated with neuroimaging changes in specific medial frontal cortex and subcortical structures, suggesting that disruption of a common systems-level mechanism may underlie its development, irrespective of the condition that causes it. (bmj.com)
  • The data obtained were also correlated with behavioral/cognitive tests and scales assessing global cognitive efficiency, apathy, cognitive disinhibition, frontal syndrome, depression and anxiety. (frontiersin.org)
  • Apathy scores were negatively correlated with several GM clusters in frontal regions, including the frontal inferior operculum and the left dorsal anterior cingulate cortex. (ovid.com)
  • These findings are consistent with the hypotheses that GDB encompasses at least three processes, that these are supported by a large-scale neural network within specific portions of the frontal lobe, and that degradation of any one of these prefrontal regions in bv FTD may contribute to apathy. (elsevier.com)
  • You are dealing with a case of apathy, but that doesn't mean it defines you or who you are. (addicted2success.com)
  • What you will read below are the criteria that must be taken into account for the diagnosis of apathy: If these symptoms are not due to an intellectual or cognitive deficit, to some type of emotional disturbance or to a decrease in the level of consciousness, then it is probably a case of apathy. (bancuriok.com)
  • Pathological apathy, characterised by extreme forms of apathy, is now known to occur in many different brain disorders, including neurodegenerative conditions often associated with dementia such as Alzheimer's disease, and psychiatric disorders such as schizophrenia. (wikipedia.org)
  • This 2-page fact sheet (PDF) explains there are three forms of apathy, that it is distinct from depression, and how it can be diagnosed. (stanford.edu)
  • The papers in this issue encompass a broad spectrum of clinical aspects of apathy with a clear overarching theme of apathy as an important behavioural syndrome which warrants careful study of its features, diagnosis and management. (hindawi.com)
  • These important nosological problems, as well as issues related to the assessment of apathy, will be the focus of the present review article. (bmj.com)
  • The behavioral and biological mechanisms of apathy, however, are not well understood. (elsevier.com)
  • This short webpage distinguishes between depression and apathy. (stanford.edu)
  • In this study, we assessed the pattern of association between apathy and default mode network (DMN), salience network and central executive network (CEN) in aMCI subjects. (dovepress.com)
  • We explored the patterns of association between apathy inventory (IA) total score and the whole-brain voxel-wise FCs of the DMN, salience network and CEN in aMCI subjects. (dovepress.com)
  • Our findings suggest that distinctive patterns of association between apathy and FCs in the DMN and CEN in the aMCI group might reflect the putative role of functional network change in the development of apathy in aMCI. (dovepress.com)
  • The main objective of this study is to look into the association between apathy severity and the caregiver burden and also identify significant predictors of apathy. (ovid.com)
  • Apathy occurs frequently, and with substantial impact on quality of life, in a broad range of neurological and psychiatric conditions. (bmj.com)
  • In a clinical context, the term "apathy" refers to a clustering of behavioural and emotional symptoms that manifests as diminished interest and involvement in normal purposeful behaviour, diminished emotional responsiveness, and a lack of initiation and drives to complete nonroutine activities. (hindawi.com)
  • Their findings suggest that the different anatomical substrates of the respective dementia types may drive the different clinical expression of apathy, which may, in turn, inform the diagnosis of the dementia type. (hindawi.com)
  • Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimer's Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months. (clinicaltrials.gov)
  • In parallel with this growing recognition of the clinical importance of apathy, significant advances have been made in understanding normal motivated behaviour in humans and animals. (bmj.com)
  • Finally, we relate these findings to clinical apathy, demonstrating the homologies between this basic neuroscience work and emerging behavioural and physiological evidence from patient studies of this syndrome. (bmj.com)
  • However, despite its clinical importance, there remains limited understanding of mechanisms underlying apathy. (nih.gov)
  • Apathy is one of the six clinical criteria for the behavioral variant of frontotemporal dementia (bvFTD), and it is almost universal in this disease. (frontiersin.org)
  • A structured clinical interview and a proposal for diagnostic criteria for apathy in dementia have been recently validated. (bmj.com)
  • Other relevant issues, such as epidemiology, demographic and clinical correlates, and putative mechanism of apathy in specific neuropsychiatric conditions, will not be directly addressed. (bmj.com)
  • The primary outcome for apathy (Apathy Evaluation Scale-Clinician) and secondary outcomes for cognition (Mini-Mental State Examination, Modified Mini-Mental State Examination), functional status (activities of daily living, instrumental activities of daily living), improvement and severity (Clinical Global Impressions Scale [CGI]), caregiver burden (Zarit Burden Scale), and depression (Cornell Scale for Depression in Dementia) were measured at baseline and at 4, 8, and 12 weeks. (nih.gov)
  • Based on promising, preliminary results from a previous clinical trial, the researchers are investigating the benefits of methylphenidate (commonly known as Ritalin) drug therapy for Alzheimer's-related apathy. (uhhospitals.org)
  • CONCLUSIONS: Clinical statements to guide the routine management of agitation, anxiety, apathy, psychosis, and sleep disorders in HD have been developed. (garvan.org.au)
  • The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. (nih.gov)
  • The present findings set the stage for future larger-scale studies confirming the structural and neurochemical substrates of apathy in schizophrenia. (ovid.com)
  • ADMET 2 will enroll participants from real world settings such as outpatient, nursing home, and assisted living facilities and will examine the effects of methylphenidate on apathy and cognition. (clinicaltrials.gov)
  • Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer's Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. (nih.gov)
  • The authors' objective was to study the effects of methylphenidate on apathy in Alzheimer's disease. (nih.gov)
  • After adjusting for baseline, the methylphenidate group had significantly greater improvement in apathy than the placebo group at 4 weeks, 8 weeks, and 12 weeks. (nih.gov)
  • Methylphenidate improved apathy in a group of community-dwelling veterans with mild Alzheimer's disease. (nih.gov)
  • Addressing Possible Effects of Sleep Apnea in a Study of Methylphenidate for Apathy in Alzheimer's Disease: Response to Kolla and Mansukhani. (nih.gov)
  • Methylphenidate and Apathy in Alzheimer's Disease: Is Sleep Apnea a Confounding Effect? (nih.gov)
  • WHEELING - West Virginia University will help the state turn "apathy into ambition and recession into recovery," WVU President E. Gordon Gee vowed Monday during his fall "State of the University" address. (weirtondailytimes.com)
  • It provides three rating scales to help diagnose apathy in Parkinson's, medication and counseling options to treat apathy, education and lifestyle changes to relieve apathy symptoms. (stanford.edu)
  • Medication options to treat apathy are, unfortunately, limited. (michaeljfox.org)
  • The solution requires us to overcome apathy. (americamagazine.org)
  • Successful people strive no matter what they feel by applying their will to overcome apathy, doubt or fear. (addicted2success.com)
  • A study published Wednesday in the journal Neurology, and funded by the National Institutes of Health's National Institute of Aging, found that older folks, who are apathetic - but not depressed - may be suffering from smaller brain volumes than those without apathy. (cnn.com)
  • Just as signs of memory loss may signal brain changes related to brain disease, apathy may indicate underlying changes,' says study author Lenore J. Launer with the National Institute on Aging and a member of the American Academy of Neurology. (cnn.com)
  • If so, your apathy may be down to specific brain differences, according to a team of researchers from Oxford University in the UK. (medicalnewstoday.com)
  • He and his team decided to study healthy people to determine whether there were any brain differences that could underpin apathy. (medicalnewstoday.com)
  • Apathy may be one of the most common behavioural symptoms of neurodegenerative and other brain disorders yet it is one of the most underrecognised, underdiagnosed, and poorly managed aspects of these diseases. (hindawi.com)
  • Apathy has also been shown to correlate with a poorer adherence to medication regimens and/or response to treatment (as after deep brain stimulation surgery, for example). (michaeljfox.org)
  • All underwent brain MRI scans and were later asked questions that measured their apathy symptoms, such as lack of interest in things, giving up activities they once enjoyed and a lack of energy. (cnn.com)
  • And the fact that participants in our study had apathy without depression should turn our attention to how apathy alone could indicate brain disease. (cnn.com)
  • Although several prior works reported that apathy is associated with conversion to Alzheimer's disease in individuals with amnestic mild cognitive impairment (aMCI), effects of apathy on the functional connectivity (FC) of the brain remain unclear. (dovepress.com)
  • Distinct structural brain circuits indicate mood and apathy profiles in bipolar disorder. (uio.no)
  • Voxel-based morphometry (VBM) was used to explore the correlations between whole-brain GM and i) Apathy, and ii) Affective Flattening, respectively. (ovid.com)
  • In this review we develop a conceptual framework for understanding pathological apathy based on this current understanding of normal motivated behaviour. (bmj.com)
  • Today there are several guides with criteria for the diagnosis of apathy, such as the, According to the data obtained by applying the. (bancuriok.com)
  • Today there are several guides with criteria for the diagnosis of apathy, such as the Apathy Evaluation Scale for example. (bancuriok.com)
  • Behavioural syndromes such as apathy may inform diagnostic aspects of different types of dementia. (hindawi.com)
  • Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. (bmj.com)
  • In summary, apathy is increasingly recognised as a common behavioural syndrome associated with neuropsychiatric disorders. (bmj.com)
  • Rather than the preferred human lifestyle, apathy is now considered a defective behavioural state. (bmj.com)
  • Apathy is a complex, behavioural disorder associated with reduced spontaneous initiation of actions. (pubmedcentralcanada.ca)
  • At the recent 2017 World Health Summit - one of the world's most prestigious strategic forums on global health - a group of prominent global experts participated in a panel discussion on vaccination apathy, assessing the extent of influence it has on vaccination uptake, its causes, the role of healthcare providers, and how behavioural economics can help understand and address it. (presseportal.de)
  • In dementia apathy represents the most common behavioral disturbance and the frequency of an apathic syndrome tend to increase with the severity of the disease. (bancuriok.com)
  • This exploration deficit was correlated with apathy, disinhibition and cognitive and behavioral dysexecutive syndromes. (frontiersin.org)
  • Here we present a very rare case with profound apathy following bilateral, focal lesions of the basal ganglia, with globus pallidus regions that connect with orbitofrontal (OFC) and ventromedial prefrontal cortex (VMPFC) particularly affected. (pubmedcentralcanada.ca)
  • Here we report one such individual with profound apathy following focal, bilateral lesions largely involving the globus pallidus (GPi) of the basal ganglia who provides a rare opportunity to understand both the neurobiology and pharmacological modulation of the condition. (pubmedcentralcanada.ca)
  • 1. The prevalence of post-stroke apathy (PSA) at 3 months was 24.7% among 267 stroke survivors. (hkmj.org)
  • Apathy is something that all people face in some capacity and is a natural response to disappointment, dejection, and stress. (wikipedia.org)
  • With the addition of the handheld device and the screen between people, apathy has also become a common occurrence on the net as users observe others being bullied, slandered, threatened or sent disturbing images. (wikipedia.org)
  • What we are seeing not just is Washington, D.C. but across the nation is the results of fifty plus years of apathy of the American people. (newswithviews.com)
  • Here, item response theory [ 2 ] was used as a basis to explore a possible early screening tool for apathy in elderly people. (hindawi.com)
  • Apathy can be very distressing for family members, when people no longer want to get together with family or friends or don't seem interested in what they used to enjoy," said researcher Dr. Meredith Bock. (consumeraffairs.com)
  • Kolkata, July 27 (PTI) A heart-wrenching video of a woman crying and pleading for help from bystanders to help her sexagenarian husband, a suspected COVID-19 patient, into an ambulance at Bongaon in West Bengal went viral and the apathy of the people seen around them has come in for flak. (yahoo.com)
  • The research shows how it may be possible to make a pill to restore vigor in people suffering from chronic fatigue and apathy brought on by cancer, congestive heart failure, kidney disease, and many other conditions - without the side-effects of stimulants such as caffeine or amphetamines. (oregonlive.com)
  • Older age and more severe motor symptoms also seem to put people at higher risk of developing apathy. (michaeljfox.org)
  • People with apathy usually don t realize there is a problem. (michaeljfox.org)
  • Stop bitching about it, you have a problem with apathy, don t use lame tactics to make people choose your side agains him/her. (offspring.com)
  • How do the levels of different types of apathy change over time in people living with MND? (uea.ac.uk)
  • What impact do apathy subtypes have on wellbeing, quality of life and caregiver burden in people with MND and their families? (uea.ac.uk)
  • Scientists at the University Medical Center Utrecht in the Netherlands found that people with two or more of these symptoms had 1.4% smaller gray matter and 1.6% less white matter in their brains than those who showed little or no apathy. (cnn.com)
  • Apathy symptoms are common in older people without dementia. (cnn.com)
  • But the data does seem to show, they say, that apathy in older people could signal something more than just moodiness. (cnn.com)
  • If these findings are confirmed, identifying people with apathy earlier may be one way to target an at-risk group,' notes Launer. (cnn.com)
  • So many people who are struggling with apathy are constantly complaining about their situation and just how bad things are. (addicted2success.com)
  • It is only natural for people to want to know why something so chaotic is happening to them, but others have a tendency to display another response: apathy. (myduhawk.com)
  • For people with Alzheimer's disease , apathy is one of the most prevalent behavioral symptoms, affecting 50 to 70 percent of those diagnosed, according to some studies. (uhhospitals.org)
  • In Europe, some 200 million people are members of the Apathy Party. (annaraccoon.com)
  • Neuropsychiatric literature dealing with apathy is reviewed within the framework of three … Look for small goals: read a book, take a walk in the park on Sunday, go out once to meet new people. (bancuriok.com)
  • Join a support group for people with apathy. (bancuriok.com)
  • The researchers concluded that apathy may be a manifestation of mild inflammation in elderly people. (bipolarnews.org)
  • apathy-related items on the Neuropsychiatric Inventory [ 1 ] were compared in frontotemporal dementia and Alzheimer disease. (hindawi.com)
  • Apathy can be overcome by enthusiasm, and enthusiasm can only be aroused by two things: first, an ideal, with takes the imagination by storm, and second, a definite intelligible plan for carrying that ideal into practice. (addicted2success.com)
  • Defined as a state of impassivity associated with a lack of interest, concern or enthusiasm, apathy is dissociable from depression ( Marin, 1991 ). (pubmedcentralcanada.ca)
  • Apathy noun lack of interest, enthusiasm, or concern. (annaraccoon.com)
  • Apathy and cortical atrophy in Alzheimer's disease. (nih.gov)
  • flat emotions, emotional dullness / blunting, apathy, anhedonia (it's like being a Vulcan or a Borg drone) # loss of libido / no sex drive: I have no problem getting 'him' hard, but there is no joy in it anymore. (psychcentral.com)
  • Apathy should be distinguished from reduced affect display, which refers to reduced emotional expression but not necessarily reduced emotion. (wikipedia.org)
  • Learn about the possible causes of apathy, depression and anxiety and how these psychological conditions might affect the emotional and mental health of a person with dementia. (alzheimers.org.uk)
  • Those with apathy, on the other hand, tend to show emotional indifference rather than feeling depressed. (alzinfo.org)
  • Apathy may not be a clearly defined emotional state, but it is a serious one. (addicted2success.com)
  • The second PANSS pICA profile generally covered blunted affect, emotional withdrawal, passive/apathetic social withdrawal, depression and active social avoidance, exhibiting a withdrawal or apathy dominating component. (uio.no)
  • OBJECTIVE: We aimed to develop expert-based recommendations regarding the management of agitation, anxiety, apathy, psychosis, and sleep disorders. (garvan.org.au)
  • Overall, the researchers determined that severe apathy in older age was associated with an 80 percent increased risk of developing dementia. (consumeraffairs.com)
  • It is responsible for the most severe form of apathy and in most cases the lesions affect bilaterally the associative and limbic territories of the internal portion of the globus pallidus. (nih.gov)
  • Abulia is considered a more severe type of apathy, but its nosological position is still unclear. (bmj.com)
  • It is not always seen or even connected, but there is a very real link between an individual with Asperger's Syndrome experiencing stress, and there suddenly being a response of severe apathy. (bancuriok.com)
  • These findings reveal that effort sensitivity and translations of intentions into actions might make a critical contribution to behavioral apathy," the researchers conclude. (medicalnewstoday.com)
  • Notably, the regions associated with apathy scores were distinct from those associated with Affective Flattening, and these findings remained after controlling for antipsychotic medication dosage. (ovid.com)
  • Depression is characterized by strong negative emotions and feelings of sadness and hopelessness, while apathy is defined as a chronic state of indifference or lack of emotion. (uhhospitals.org)
  • Someone with apathy shows a lack of interest, emotion and purpose. (stanford.edu)
  • Apathy is a lack of those feelings. (bancuriok.com)
  • After nine years, the researchers evaluated the participants' medical records to determine how apathy played a role in the development of dementia. (consumeraffairs.com)
  • The participants were divided into one of three groups based on their levels of apathy, and the researchers learned that those who were the most apathetic at the start of the study had a significantly higher risk of developing dementia. (consumeraffairs.com)
  • Therefore, this multicenter, multidisciplinary study primarily aims to explore apathy subtype trajectories throughout the progression of the disease and its associations with quality of life, well-being and caregiver burden in MND. (uea.ac.uk)
  • Nonparametric Spearman correlational analyses examined relationships between apathy and caregiver burden scores. (ovid.com)
  • This study has shown high association of apathy with caregiver burden both in AD & aMCI. (ovid.com)