Lack of emotion or emotional expression; a disorder of motivation that persists over time.
Observable manifestations of impaired psychological functioning.
A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for circulatory disorders and in other applications as a D2 agonist.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
Mood or emotional responses dissonant with or inappropriate to the behavior and/or stimulus.
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
Intracranial tumors originating in the region of the brain inferior to the tentorium cerebelli, which contains the cerebellum, fourth ventricle, cerebellopontine angle, brain stem, and related structures. Primary tumors of this region are more frequent in children, and may present with ATAXIA; CRANIAL NERVE DISEASES; vomiting; HEADACHE; HYDROCEPHALUS; or other signs of neurologic dysfunction. Relatively frequent histologic subtypes include TERATOMA; MEDULLOBLASTOMA; GLIOBLASTOMA; ASTROCYTOMA; EPENDYMOMA; CRANIOPHARYNGIOMA; and choroid plexus papilloma (PAPILLOMA, CHOROID PLEXUS).
An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
A plant genus of the family POLYGALACEAE that contains onjisaponins, xanthones, pyrones, and benzophenones. The name is similar to other snakeroots such as ASARUM; SANICULA; ARISTOLOCHIA; AGERATINA; and others.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Sequential operating programs and data which instruct the functioning of a digital computer.
That branch of learning which brings together theories and studies on communication and control in living organisms and machines.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Activities concerned with governmental policies, functions, etc.
Individuals enrolled in a school or formal educational program.
Those factors which cause an organism to behave or act in either a goal-seeking or satisfying manner. They may be influenced by physiological drives or by external stimuli.
Educational institutions.
A system of government in which there is free and equal participation by the people in the political decision-making process.
Sound that expresses emotion through rhythm, melody, and harmony.
Modulation of human voice to produce sounds augmented by musical tonality and rhythm.
The use of music as an adjunctive therapy in the treatment of neurological, mental, or behavioral disorders.
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
All the organs involved in reproduction and the formation and release of URINE. It includes the kidneys, ureters, BLADDER; URETHRA, and the organs of reproduction - ovaries, UTERUS; FALLOPIAN TUBES; VAGINA; and CLITORIS in women and the testes; SEMINAL VESICLES; PROSTATE; seminal ducts; and PENIS in men.
An individual's objective and insightful awareness of the feelings and behavior of another person. It should be distinguished from sympathy, which is usually nonobjective and noncritical. It includes caring, which is the demonstration of an awareness of and a concern for the good of others. (From Bioethics Thesaurus, 1992)
A geographical area of the United States comprising the District of Columbia, Delaware, Maryland, New Jersey, New York, and Pennsylvania.
Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset.
The act or practice of literary composition, the occupation of writer, or producing or engaging in literary work as a profession.
A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398)

Mutual gaze in Alzheimer's disease, frontotemporal and semantic dementia couples. (1/48)

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The Neuropsychiatric Inventory-Clinician rating scale (NPI-C): reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia. (2/48)

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Are the available apathy measures reliable and valid? A review of the psychometric evidence. (3/48)

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The trajectory of apathy after deep brain stimulation: from pre-surgery to 6 months post-surgery in Parkinson's disease. (4/48)

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Apathy, but not depression, reflects inefficient cognitive strategies in Parkinson's disease. (5/48)

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Treatment strategy in schizophrenia combined with eating disorder. (6/48)

Like any other patient, a schizophrenic patient can get a physical illness, too. As such patients tend to ignore reality and neglect themselves and are stigmatized by society, due to which their physical symptomatology is often ignored, physical illness can remain undetected. If the schizophrenic patient is observed and adequate care is provided by the family, family doctor and a psychiatrist, it is possible to recognize the physical illness and intervene promptly. We are presenting a case of a female patient who has been treated for schizophrenia for a number of years. The treatment was mostly ambulatory (i.e. the patient was hospitalized twice) and consisted of first-generation antipsychotics. During the past two years, for reasons unknown, the patient stopped taking regular meals and as a result lost significant body weight, became apathetic and withdrawn, started avoiding social contacts and neglected personal hygiene. She reportedly took the psychopharmaca regularly, but rarely attended psychiatric follow-up consultations. Due to substantial weight loss and hypotonia, correction of antipsychotic was made and internist treatment administered. The choice of olanzapine was not an accidental one. We decided to take advantage of its side effect for the treatment of an anorectic syndrome. Interdisciplinary cooperation proved to be a justified decision.  (+info)

A randomized clinical trial of theory-based activities for the behavioral symptoms of dementia in nursing home residents. (7/48)

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Physical activity attenuates neuropsychiatric disturbances and caregiver burden in patients with dementia. (8/48)

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In their recent study,3 Dr. Chow and her colleagues set out to localize clusters of apathy symptoms empirically, with actual patients with dementia, to see whether the affective, behavioural, or cognitive apathy symptoms tended to occur together or in isolation, and whether apathy typically co-occurs with other types of behavioural disturbances.. Dr. Chow showed combined data from Baycrest, Sunnybrook [Health Sciences Centre], UC San Francisco, and UCLA, showing results on the Neuropsychiatric Inventory (NPI). On the section of the NPI that deals with apathy, patients are questioned on spontaneous activity, spontaneity in conversation, participation in former activities, participation in former chores, demonstration of interest in others, investment in friends and family, and degree of affection.. Results showed that, for those with either FTD or Dementia of Alzheimers type (DAT), the most common type of apathy, when present, was a decrease in spontaneous activity. Comparing the percentage of ...
In their recent study,3 Dr. Chow and her colleagues set out to localize clusters of apathy symptoms empirically, with actual patients with dementia, to see whether the affective, behavioural, or cognitive apathy symptoms tended to occur together or in isolation, and whether apathy typically co-occurs with other types of behavioural disturbances.. Dr. Chow showed combined data from Baycrest, Sunnybrook [Health Sciences Centre], UC San Francisco, and UCLA, showing results on the Neuropsychiatric Inventory (NPI). On the section of the NPI that deals with apathy, patients are questioned on spontaneous activity, spontaneity in conversation, participation in former activities, participation in former chores, demonstration of interest in others, investment in friends and family, and degree of affection.. Results showed that, for those with either FTD or Dementia of Alzheimers type (DAT), the most common type of apathy, when present, was a decrease in spontaneous activity. Comparing the percentage of ...
ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers dementia. Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimers Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months.. ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. Safety will also be measured by examining neuropsychiatric symptoms other than apathy using the Neuropsychiatric Inventory (NPI).. Changes from baseline to 6 months in other neuropsychological assessments as measured using the Dementia Apathy Interview and Rating (DAIR) scale will also be assessed.. Cost-effectiveness will be measured by ...
ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers dementia. Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimers Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months.. ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. Safety will also be measured by examining neuropsychiatric symptoms other than apathy using the Neuropsychiatric Inventory (NPI).. Changes from baseline to 6 months in other neuropsychological assessments as measured using the Dementia Apathy Interview and Rating (DAIR) scale will also be assessed.. Cost-effectiveness will be measured by ...
TY - JOUR. T1 - Apathy is associated with ventral striatum volume in schizophrenia spectrum disorder. AU - Roth, Robert M.. AU - Garlinghouse, Matthew A.. AU - Flashman, Laura A.. AU - Koven, Nancy S.. AU - Cara Pendergrass, J.. AU - Ford, James C.. AU - McAllister, Thomas W.. AU - Saykin, Andrew. PY - 2016. Y1 - 2016. N2 - Apathy is prevalent in schizophrenia, but its etiology has received little investigation. The ventral striatum (VS), a key brain region involved in motivated behavior, has been implicated in studies of apathy. We therefore evaluated whether apathy is associated with volume of the VS on MRI in 23 patients with schizophrenia using voxel-based morphometry. Results indicated that greater self-reported apathy severity was associated with smaller volume of the right VS even when controlling for age, gender, depression, and total gray matter volume. The finding suggests that apathy is related to abnormality of brain circuitry subserving motivated behavior in patients with ...
OBJECTIVES: Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimers disease (AD), associated with greater functional decline and caregiver distress. The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. METHODS: Semi-structured interviews were conducted with 111 AD patients and their caregivers as part of the European multi-centre study AddNeuroMed. Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T MRI scanner and the images analysed using an automated analysis pipeline. RESULTS: We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and
OBJECTIVES: Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimers disease (AD), associated with greater functional decline and caregiver distress. The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. METHODS: Semi-structured interviews were conducted with 111 AD patients and their caregivers as part of the European multi-centre study AddNeuroMed. Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T MRI scanner and the images analysed using an automated analysis pipeline. RESULTS: We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and
Background: Geriatric depression with subjective memory complaints increases the risk for Alzheimers Disease. Memantine, a neuroprotective drug, can improve depression and help prevent cognitive decline. In our 6-months clinical trial, escitalopram/memantine (ESC/MEM) improved mood and cognition compared to escitalopram/placebo treatment (ESC/PBO; NCT01902004). In this report, we investigated whether baseline brain white matter integrity in fronto-limbic-striatal tracts can predict clinical outcomes using fractional anisotropy (FA).Methods: Thirty-eight older depressed adults (mean age = 70.6, SD = 7.2) were randomized to ESC/MEM or ESC/PBO and underwent diffusion-weighted imaging (DWI) at 3 Tesla at baseline. Mood was assessed using the Hamilton Depression Rating Scale (HAMD), apathy using the Apathy Evaluation Scale (AES) and anxiety using the Hamilton Anxiety Scale (HAMA) at baseline and 6-months follow-up. FA was extracted from seven tracts of interest (six in each hemisphere and one commissural
For the study, researchers examined 79 adolescents ages 14 to 18, who were classified as recent regular cannabis users (36) or light users (43). Frequency and amount of substance use were assessed across participants lifetime and during the past 30 days, and motivation was measured through the Apathy Evaluation Scale and Motivation and Engagement Scale. To examine associations between cannabis use (CU) and motivation indices, researchers conducted a series of two-step hierarchical multiple regressions.. After controlling for confounds, no significant differences were observed between regular and light users on any motivation index, states the study. Similarly, no associations between motivation and lifetime or past 30-day CU amount were observed.. The study concludes by stating; Our findings do not support a link between reduced motivation and CU among adolescents after controlling for relevant confounds.. The full study, conducted by researchers at Florida International University, ...
January 29, 2010. Most people think of memory loss when they think of Alzheimers. But the disease can cause a wide range of behavioral and personality changes as well. One of the most common is apathy, or loss of motivation, and the condition seems to have a biological basis. Using brain scans, researchers in Sweden report that changes in the brains white matter are a common feature in apathetic patients who have Alzheimers or other forms of dementia.. Apathy is one of the most common psychological problems associated with dementia. Just over half of all people with Alzheimers are emotionally blunted and lack motivation and initiative. As the disease worsens, apathy often grows worse.. Studies suggest there is a common biological reason behind apathy, irrespective of whether a person has Alzheimers or other forms of dementia. The changes occurred in areas deep in the brain that are connected to the brains frontal lobes, which are critical for taking initiatives and the ability to ...
bill and melinda gates foundation, Bill Gates, donation, global fund, HIV, malaria, Reject Apathy, Reject Apathy, tuberculosis, Reject Apathy
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Apathy. It has become a major issue for so many people today. While many people associate apathy with a lack of passion or motivation, it is technically defined as the absence of emotion.
Apathy Just Begun lyrics & video : [Funkmaster flex sample] [Celph Titled] Yo what the f**k are yall thinkin Lettin Apathy get on the mic Thats like unleashing a f**king atom...
BACKGROUND: Alzheimers disease (AD) is characterized not only by cognitive and functional decline, but also often by the presence of neuropsychiatric symptoms. Apathy, which can be defined as a lack of motivation, is one of the most prevalent neuropsychiatric symptoms in AD and typically leads to a worse quality of life and greater burden for caregivers. Treatment options for apathy in AD are limited, but studies have examined the use of the amphetamine, methylphenidate. The Apathy in Dementia Methylphenidate Trial (ADMET) found that treatment of apathy in AD with methylphenidate was associated with significant improvement in apathy in two of three outcome measures, some evidence of improvement in global cognition, and minimal adverse events ...
A. H. Craig, J. L. Cummings, L. A. Fairbanks, L. Itti, B. L. Miller, J. Li, I. Mena, Cerebral blood flow correlates of apathy in Alzheimer disease, Archives of Neurology, Vol. 53, No. 11, pp. 1116-20, Nov 1996. [1998 impact factor: 3.375] (Cited by 231). Abstract: BACKGROUND: Apathy is a pervasive noncognitive neuropsychiatric disturbance in Alzheimer disease, which causes significant caregiver distress. The neuroanatomical substrate of apathy is not well understood. OBJECTIVE: To study the relationship between regional cerebral blood flow and the presence and severity of the personality disturbance, apathy, in individuals with Alzheimer disease. DESIGN: Analysis of the relationship between regional cerebral blood flow as measured by single photon emission computed tomography and severity of apathy as measured by the Neuropsychiatric Inventory using an analysis of variance design. We examined regional cerebral perfusion alterations as measured by xenon 133Xecalibrated technetium Tc 99m ...
k4140] High doses of dopamine are usually needed to help patients suffering from apathy. In one study, seven out of eight patients who became depressed following liver transplants and were given methylphenidate, or Ritalin, a drug that elevates dopamine levels, showed improved motivation in pursuing their rehabilitation regimens and less social withdrawal and apathy than they exhibited before taking the drug. For apathy patients, drugs are not the final cure. They also need assistance in practicing techniques to help themselves. Education of the family is an important job for the therapist, too. Treatment of apathy raises some complex human rights issues, because these patients may be competent enough to make some decisions but not others. They are also prone to anxiety, which must be relieved so that they will consider options and get involved with life again. Treating apathy is also important in depressed patients. Drugs can be used to bring about rapid improvement at an early stage. Since ...
National Institutes of Health Funding to Support Ongoing Advancement of Innovative Treatments in Preventing and Treating Alzheimers Disease and Alzheimers Disease-Related DementiasLOS ANGELES, Aug. 05, 2021 (GLOBE NEWSWIRE) -- Praxis is proud to announce to be the recipient of a Fast-Track SBIR award to develop treatment for apathy in Alzheimers Disease. The award, in its second of three years and expected to total $2.9 million, will support the IND-enabling work to advance the Companys lead
TY - JOUR. T1 - Apathy is associated with activities of daily living ability in Parkinsons disease. AU - Laatu, S. AU - Karrasch, Mira. AU - Martikainen, K. AU - Marttila, R. PY - 2013. Y1 - 2013. M3 - Artikel. VL - 35. SP - 249. EP - 255. JO - Dementia and Geriatric Cognitive Disorders. JF - Dementia and Geriatric Cognitive Disorders. SN - 1420-8008. IS - 5. ER - ...
TY - JOUR. T1 - Apathy is associated with activities of daily living ability in Parkinsons disease. AU - Laatu, S. AU - Karrasch, Mira. AU - Martikainen, K. AU - Marttila, R. PY - 2013. Y1 - 2013. M3 - Artikel. VL - 35. SP - 249. EP - 255. JO - Dementia and Geriatric Cognitive Disorders. JF - Dementia and Geriatric Cognitive Disorders. SN - 1420-8008. IS - 5. ER - ...
Apathy is a debilitating and under-recognized condition that has a significant impact in many neurodegenerative disorders. In Parkinsons disease, it is now known to contribute to worse outcomes and a reduced quality of life for patients and carers, adding to health costs and extending disease burde …
Apathy is a non-motor symptom of Parkinson s disease that is sometimes misinterpreted as laziness, poor initiative or depression.
Author: Frisch, Stefan et al.; Genre: Journal Article; Published in Print: 2017-12; Title: Apathy and cognitive deficits in patients with transient global ischemia after cardiac arrest
(KudoZ) French to English translation of L ACEDIE: acedia (A mental disorder characterized by apathy and melancholia) [MEDICAL - Medical (general) (Medical)].
Immortal lyrics from Its The Bootleg Muthaf_ckas!: Vol.1 album and other Apathy songs, music. Its The Bootleg Muthaf_ckas!: Vol.1 cover.
Abstract: Objectives: People with Huntingtons disease (HD) experience poor social quality of life, relationship breakdown, and social withdrawal, which are mediated to some extent by socially debilitating neuropsychiatric symptoms, such as apathy and disinhibition. Social cognitive symptoms, such as impaired emotion recognition, also occur in HD, however, the extent of their association with these socially debilitating neuropsychiatric symptoms is unknown. Our study examined the relationship between emotion recognition and symptom ratings of apathy and disinhibition in HD. Methods: Thirty-two people with premanifest or symptomatic-HD completed Part 1 of The Awareness of Social Inference Test (TASIT), which is a facial emotion recognition task. In addition, we obtained severity ratings for apathy and disinhibition on the Frontal Systems Behavior Scale (FrSBe) from a close family member. Our analyses used motor symptom severity as a proxy for disease progression. Results: Emotion recognition ...
IUPsyS is psychologys international organization in Official Relations with the WHO and these were renewed in January 2014. In this capacity IUPsyS was appointed to the International Advisory Group (IAG) for the Revision of ICD-10 Mental and Behavioural Disorders in 2006 and Secretary General, Dr Ann Watts, currently represents the Union on the IAG. Psychologys contributions to the development of ICD-11 remain a key IUPsyS strategic priority. To support this important initiative the IUPsyS has seconded psychologist Dr Geoff Reed to the WHO to serve as Senior Project Officer for the Mental and Behavioural Disorders component of the ICD-10 revision. In this capacity Dr Reed reports to the Director of the WHO Department of Mental Health and Substance Abuse, Dr Shekhar Saxeena, and Dr Pierre Ritchie, Co-Main Representative (Psychology) to WHO. Dr Reeds work at WHO has been suported by major grants from the American Psychological Association (APA) to IUPsyS (2008-12; 2013-14;2015-6). The Agreement ...
Psychometric support was found for all 3 versions of the BFNE, although the longer 12-item BFNE-II did not improve measurement compared to the shorter 8-item versions (BFNE-S and BFNE-8). Of these 2, the BFNE-S has been more widely studied, with strong validity data in a greater number of population …
This study examined the brain bases of early human social cognitive abilities. Specifically, we investigated whether cortical regions implicated in adults perception of facial communication signals are functionally active in early human development. Four-month-old infants watched two kinds of dynamic scenarios in which a face either established mutual gaze or averted its gaze, both of which were followed by an eyebrow raise with accompanying smile. Haemodynamic responses were measured by near-infrared spectroscopy, permitting spatial localization of brain activation (experiment 1), and gamma-band oscillatory brain activity was analysed from electroencephalography to provide temporal information about the underlying cortical processes (experiment 2). The results revealed that perceiving facial communication signals activates areas in the infant temporal and prefrontal cortex that correspond to the brain regions implicated in these processes in adults. In addition, mutual gaze itself, and the ...
Objective: Aging societies will bring an increase in the number of long-term care patients with mental-physical multimorbidity (MPM). This paper aimed to describe the natural course of neuropsychiatric symptoms (NPS) in patients with MPM in the first 8 months after admission to a geronto-psychiatric nursing home (GP-NH) unit. Methods: Longitudinal cohort study among 63 patients with MPM no dementia living in 17 GP-NH units across the Netherlands. Data collection consisted of chart review, semi-structured interviews, and brief neuropsychological testing, among which our primary outcome measure the Neuropsychiatric Inventory (NPI). Descriptive and bivariate analyses were conducted. Results: Our study showed a significant increase of the NPI total score (from 25.3 to 29.3, p = 0.045), and the total scores of a NPI hyperactivity cluster (from 9.7 to 11.8, p = 0.039), and a NPI mood/apathy cluster (from 7.7 to 10.1, p = 0.008). Just over 95% had any clinically relevant symptom at baseline and/or six ...
The goal of this research was to evaluate the impact of ACES (Accompagnement Collaborative des Enseignants du Secondaire), a training program for high school teachers aimed at facilitating the educational integration of students with special needs. Offered individually or in groups, the program was well received by all stakeholders and had a positive impact on teachers, students and the classroom climate. The program positively influenced teachers attitudes towards their students, their understanding of behavioural disorders, their use of positive and proactive intervention strategies, and the student-teacher relationship.. Teachers who took part in the program had a significantly lower level of teaching stress than those in the control groups. While little difference was observed between the two versions of the program, the group training was more popular with all parties concerned.. ...
Psychiatric and Behavioural Disorders in Intellectual and Developmental Disabilities General Medical Ebook by Nick Bouras, Geraldine Holt,
A number of biological markers have been implicated in late life depression with inconsistent results. The present study examined the relationship between several serum based biomarkers and symptoms of depression in a sample of elderly women with AD or cognitively intact. Methods 171 females (58 with AD and 113 cognitively intact) were recruited from the Longitudinal Research Cohort of the Texas Alzheimers Research and Consortium (TARC). Stepwise regressions were conducted with GDS total and subscales and a panel of biomarkers (CRP, IL-10, IL-1α, TNF-α, ICAM-1, BDNF, and MIF). ApoE4 status was coded (carrier or non-carrier), and the results were analyzed by cognitive status (AD or controls). Results: None of the biomarkers significantly predicted total GDS score for AD cases, controls or sample as a whole. For the Controls, ICAM significantly predicted Dysphoria and level of Apathy. Among AD patients, MIF, ICAM, and CRP, were significantly associated with Apathy. MIF and ICAM were inversely
This mutation was identified in a Spanish family with AD that progressed relatively slowly, with a wide range of ages of onset (Lladó et al., 2010). A total of six family members were affected, with ages of onset ranging from the fifth to eighth decade of life. The mutation was found in all three affected members who were tested, and was absent from 121 controls and 163 AD patients.. The proband was a man who developed cognitive decline with behavioral abnormalities at age 57. His behavioral symptoms included apathy, irritability, social withdrawal, and, ultimately, marked aggressiveness for which he was institutionalized at age 70. Another family member carrying the mutation also initially presented with apathy and irritability, and subsequently became aggressive, but her symptoms started earlier, at age 42. Surprisingly, a third mutation carrier in the same family presented with typical AD at age 71. This is in contrast to the complete penetrance of PSEN1 mutations usually seen by age 65. All ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Psychic akinesia has been described in patients that are fully responsive, but with no display of goal directed activities. It is characteristic of patients with psychic akinesia to correctly perform most of their daily activities, but only after strong stimulation.42 A similar syndrome was labelled the autoactivation deficit by Laplane and Dubois, and was defined as a deficit in spontaneous activation of mental processing, observed in behavioural, cognitive or affective domains, which can be totally reversed by external stimulation that activates normal patterns of response.43 The authors listed the following symptoms of autoactivation deficit: (1) inertia (defined as the tendency to stay immobile for long periods and taking no initiatives), (2) mental emptiness (defined as lack of thoughts and no projections onto the future), (3) repetitive and stereotyped activities, (4) flat affect and (5) blunted emotional responses. Full reversal of the negative state on external stimulation was ...
Apathy is a subject near and dear to my own heart. I have shared before how hard Ohio winters are on me physically and mentally. I have come to realize that I do best when I fight back with a variety of tools such as happy lights, supplementation, outdoor time, exercise, and healthy foods. The kink in the otherwise perfect plan though can be aptly named, apathy. You may know what you need to do but you just cant work up the enthusiasm or energy to do it. You become indifferent to your … [Read more...] ...
Reduced alertness, fatigue, apathy, insomnia are often lumped together. As a rule in older folks, alertness aint what it used to be. [9] The exceptions are a wonderful thing to behold. I am surprised at finding a number of people as young as being in their fifties, who share with older folks the poor recall of names. If you think of the brain being like a computer, it is if something happened to the address book. You cant put names to the faces. Mental stress is a big contributor to the development of feeling fatigued. Multitasking is a problem. Not being able to breeze through tasks, as one did in mid-life, can prove very frustrating and stressful. Realizing that one person has little impact on the worlds problems, leads to apathy or to continue seeking solutions when in the twilight zone of sleep. Dry skin: A universal problem in older folks -- made worse from exposure to dry inside, winter air. [10] Moisturizing lotions seem to be the only remedy, but even with their use, break-through ...
What up, my punky little peanuts? This is the last installment of our three-part intro to Dead Broke Rekerds. So we have a whole other. Read more ...
The markets drift steadily higher as the delta variant thing seems like its decelerating, things are quiet on the monetary policy front and Bidens infrastructure bill advances from the Senate to the House. Earnings have been incredible across the board, and not just compared with the same quarter last year. On an absolute basis companies are reporting record high profits, cash balances, financial flexibility, consumer demand for their products and services, etc. Bank accounts are flush, brokerage accounts are spilling over with gains, 401(k) retirement plan assets are soaring and both consumers and businesses are making new investments for the future.. And its 90 degrees and sunny from coast to coast.. So, of course, were in an environment in which volatility has declined back to pre-pandemic levels and less attention is being paid to the stock market these days. Certainly nowhere near what we were experiencing a year ago. People I know in the financial media business are way down in traffic ...
The opposite of Apathy is Love. Last Saturday my husband and I joined four other couples for a dinner club and the discussion around the table was anything but apathetic. Jokes about the election year and the wild ride ahead for us Americans mingled with updates on our families and local parishes. Wine glasses clinked and Italian sauced plates scraped clean as five women and five men tried to predict how the public would soon vote and who our next president will be. The famous quote, Never talk politics or religion in polite company was disregarded and I believe with good reason. As Christians we care about our country, families and our churches and to sit back and do nothing would be considered apathetic. And apathy is the opposite of love.. Later in the evening when we resumed to the living room, the hostess presented our group with a challenge. Before Jesus ascended up to Heaven, He told his disciples to wait until the Holy Spirit has come down in power to help them. So for Ten days the ...
If you are in need of custom window treatments, then you have many different options to choose from nowadays, such as custom blinds. For example, you can customize anything from drapes to curtains to shades to shutters. You really will … Continue reading →
JP is so right!](http://confusedofcalcutta.com/2007/09/06/wondering-about-alarmapathy/). , I have lost count of the number of times Ive sat in a car whose dashboard is littered with various alerts and alarms. I have lost count of the number of times Ive seen kitchen appliances whose control panels are flashing whatever they flash. I have lost count of the number of times Ive seen televisions and video recorders and DVD players and radios and computers with bits and bobs flashing away merrily.. , […]. , Apathy sets in when we have too many alarms, too many meaningless alarms. Alarms should be risk sensors that help us make decisions that carry risk. Instead, we may be moving towards a world where nanny-state numbness is moving on to devices, and as a result apathy will increase.. , You know what I mean. You know that we live in a world where a talking bag of peanuts is no longer science fiction, where the bag says Warning: The bag you are opening contains nuts. Where you cant take ...
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In the last 4 years of funding we have defined the conditions under which T cells obviate the requirement for costimulatory signaling during activation, and med...
Wednesday, April 4. 2007 Introduction The Palestinian environment and its natural resources have been under human pressure since the Israeli occupation of 1967. The division of the West Bank into areas A, B and C with different control authority is making environmental conditions more severe as the potential for environmental protection is diminished. Along with…
But Gorakhpur is not the first such incident, and unless there is a deep dive to find and isolate the root cause, it wont be the last either
Home care. A social network of friends and family may be of help. They can revive your interest in life and your environment. The services of mental health professionals are also indispensable. With their help, you can see life from a brighter perspective. Combining medications with therapy will have a more potent effect compared to either treatment on its own.. Future treatments. Research is ongoing for treatment of chronic apathy. A possible treatment would be cranial electrotherapy stimulation. This can help in treatment of traumatic brain injury affecting the frontal lobe. The treatment involves the application of a low-voltage electric current to the forehead. It is a painless treatment. Cognitive stimulation therapy is another form of treatment. It is used mainly for treating Alzheimer patients. Cognitive stimulation therapy involves taking part in group activities for the purpose of stimulating brain waves.. ...
At the recent Patient Advocacy Conference I attended, I spoke with a community member. Weve previously met but Ive talked more with his family members. Hes always seemed to be rather shy.. He asked me how I motivate myself. Ive been asked this before. Many people with myotonic dystrophy experience both overwhelming physical fatigue as well as extreme apathy. The first time I attended the annual patient conference I participated in a panel discussion. Afterwards I had someone approach me with utter disbelief that I had the disease. Even though I appeared to be similar in age to her daughter, I appeared to function like a normal person.. The more you learn about the disease, the more you realize the diversity of symptoms and severity. Im sure there are many additional factors the research community doesnt take into account, i.e. my self-care routines are like a full-time job.. But getting back to this young man (age is relative and hes ~20 years my junior) and his question. There are ...
Recent events in the nation, perhaps most notably the We March protest that took place last week, showed that The Bahamas has begun to shake off the veil of apathy that we have slumbered under for what feels like too long. This year has been a belter for politics and people of all beliefs making their feelings known - for better or for worse. And, as art so often engages with the state of society, so it is that many of the submissions for the 8th National Exhibition (NE8) at the National Art Gallery of The Bahamas (NAGB) were brash, bold, opinionated, and deeply political; reflecting how strongly so many of us feel after the various events of 2016.
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Learn when youre using empathy vs. sympathy vs. apathy with Grammar Rules from the Writers Digest editors, including their differences and when they might overlap.
Caregiver burden is high among caregivers of PD patients (CPD). Neuropsychiatric symptoms are leading contributors to CPD burden, but whether different symptoms differentially impact domains of caregiver burden is not known. Our objective was to examine which neuropsychiatric symptoms and demographic factors contribute to different domains of caregiver burden in PD.This was a cross-sectional online survey study. Participants were recruited from the Fox Insight (FI) study and were eligible if they identified themselves as a CPD. The primary outcome was the Caregiver Burden Inventory (CBI) total score and its 5 sub-domain scores. The Neuropsychiatric Inventory Questionnaire (NPI-Q) assessed caregiver-reported neuropsychiatric symptoms in the care recipient. Multivariable linear regression models were used to characterize the associations between NPI-Q symptom severity scores and CBI scores. Covariates were caregiver age, sex, education, and caregiving duration.The sample consisted of 450 CPD, mean ...
University of Southern California DAILY @ TROJAN VOL. LXII NO. 89 LOS ANGELES, CALIFORNIA TUESDAY, MARCH 16, 1971 MARGARET MEAD Media causes apathy-Mead By JAN EDWARDS The media see campuses as dens of apathy. In fact, they bring about that state by a sort of cause-and-effect relationship. This is the observation of Margaret Mead, anthropologist and author, who said. The media say the campuses are calm, and in general the campuses are complying. At noon yesterday in Bovard Auditorium. Dr. Mead spoke to a near-capacity audience. Reviewing the past few years, she found you either have a bust or you have apathy. If youre not having a bust, then youre having apathy. But the campus image in the eye of the community is of marginal importance. she observed. The image students have of themselves is more important than the image that the media give to students. Students have been discouraged about the chances of accomplishing something. Dr. Mead believes that if an organized few are motivated ...
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Gwyn M. Vernon, M.S.N., R.N., C.R.N.P., is co-founder and national director of The Edmond J. Safra Visiting Nurse Faculty Program at the Parkinsons Foundation.. PLEASE NOTE: This web seminar is being hosted by the Parkinsons Foundation, and registration will be handled through their website, www.pdf.org.. *This web seminar is approved for AoTA contact hours in addition to CEUs approved for all ASA web seminars. Questions about registration? Call the Parkinsons Foundation at 800-457-6676.. Questions about CEUs? Call ASA at 415-974-9628.. Have technical issues? Call NetBriefings at 866-225-1532.. ...
I'm very interested to see how the 2008 presidential election affects the motivation levels of students this year. As this article in The Washington Post talks about, the 18-24 age group is notorious for being politically apathetic, particularly those who haven't gone to college, but some are hopeful that that might change. I know this is an issue that doesn't directly affect most high school students, since only a small percentage of them can participate in the voting process, but I do think a presidential election is one of the most exciting things that happens in this country, and even...
Groups consisting each of three males and three females received two i.p. injections of 2500 mg/kg separated by 24 h using an application volume of 10 ml/kg . In addition, two males were treated with an application volume of 20 ml/kg.Symptoms were recorded for up to 48 h (for males: apathy, roughened fur, emaciation, loss of weight, sunken flanks, spasm, difficulty in breathing, eyelids stuck together, slitted eyes, closed eyes, lachrymation, white tears and diarhoea; for females: apathy, roughened fur, emaciation, loss of weight, sunken flanks, spasm, shivering, slitted eyes, closed eyes) None of the animals died. Due to the results it was concluded, that there were no substantial differences between sexes. Therefore, no females were used in the definite study ...
Its a work that questions the foundation of Frederiksens upbringing, one in which his left-leaning parents assured him there was a social order in place that caught the disaffected and prevented people from falling through the cracks. Its a world that Frederiksen isnt convinced exists, as Melbournes housing crisis worsens and the citys homeless population grows. Its a social order that the plays protagonist Miss Shepherd certainly wasnt privy to.. Frederiksen plays Alan Bennett 1, while his former co-star in Matilda, James Millar, plays his characters subconscious, Alan Bennett 2. I love that device Frederiksen says. Its so clever because we all have that internal dialogue, and Im guilty of being like Alan Bennett 1, constantly trying to please people…often to my own detriment.. Despite the challenges both Bennett and Shepherd encounter in this story, Frederiksen believes it is ultimately a tale of friendship, acceptance and, where possible, of not letting people fall through ...
This week on Slate I read a controversial piece: American Jews Are Secular, Intermarried, and Assimilated: Great News! which was written about the recent Pew study on American Jews. The author, Gabriel Roth, tells American Jewry to embrace their secular, intermarried selves and that unless theyre Orthodox and believe, theres no reason to keep this race purity going on. He explains that other than Orthodox Jews, Jews will stop existing soon, and thats a good thing. (Oy!) Roth writes:. And as an intermarried Jewish nonbeliever, I think its time we anxious Jews stopped worrying and learned to love our assimilated condition-even if it means that our children call themselves half-Jewish and our grandchildren dont consider themselves Jews at all. Im not talking, here, to religious Jews, because their position is unarguable: If you believe that Jewish traditions are part of a covenant with God, of course you want your children to continue them.. Roth and I both agree that staying Jewish for ...
ally sleep has been one of the hardest things to study, but some recent studies using a PET scan and a tagged amino acid may give us some clues as to why we need to sleep. One of the theories is that we need sleep to repair proteins in the cells of the brain, which cant happen while we are awake because the brain is too busy and has too many processes happening. During a normal day while we are awake we accumulate adenosine in our brain, which signals our bodies to sleep. Sleep would eliminate the adenosine and produce more proteins for repair of the brain cells.. Humans have varying levels of sleep, but so do many animals in nature. A normal human gets somewhere between 7 and 8 hours of sleep per night, but an animal such as a lion gets up to 15 hours a day. A elephant on the other hand gets around 4 hours of sleep. One of the theories about this is that predator species can sleep more because they dont generally have many predators, while the prey species get much less sleep so they can ...
ally sleep has been one of the hardest things to study, but some recent studies using a PET scan and a tagged amino acid may give us some clues as to why we need to sleep. One of the theories is that we need sleep to repair proteins in the cells of the brain, which cant happen while we are awake because the brain is too busy and has too many processes happening. During a normal day while we are awake we accumulate adenosine in our brain, which signals our bodies to sleep. Sleep would eliminate the adenosine and produce more proteins for repair of the brain cells.. Humans have varying levels of sleep, but so do many animals in nature. A normal human gets somewhere between 7 and 8 hours of sleep per night, but an animal such as a lion gets up to 15 hours a day. A elephant on the other hand gets around 4 hours of sleep. One of the theories about this is that predator species can sleep more because they dont generally have many predators, while the prey species get much less sleep so they can ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
This is another tragedy that once again reflects the sordid state of hospitals and health care through out India. News of deaths coming from Gorakhpur, Uttar Pradesh is spiralling on a daily basis and that too from just one hospital viz. BRD Hospital, the government-run hospital of the city. It is the only hospital with reasonable faciliities in a 300-km radius and treats encephalitis patients from Gonda, Basti districts, Terai region in Nepal and eastern districts of Bihar. No State can be shown as a model. Like the farmers, the children of the poor in the India are totally neglected. 70 years of our growth of free India is yet to reach them.. A small town named Gonda in UP was at the last position among 434 cities surveyed across the country. It shall also be remembered that Gonda district is among the 10 districts in UP severely affected by Encephalitis. All this means that hygiene is one of the crucial factors in containing encephalitis, and the total failure of administration in this ...
COLLEGE STATION The more you know the less you care at least that seems to be the case with global warming. A telephone survey of 1,093 Americans by two Texas A&M University political scientists and a former colleague indicates that trend, as explained in their recent article in the peer-reviewed journal Risk Analysis. More informed respondents both feel less personally responsible for global warming, and also show less concern for global warming, states the article, titled Personal Efficacy, the Information Environment, and Attitudes toward Global Warming and Climate Change in the USA.. The study showed high levels of confidence in scientists among Americans led to a decreased sense of responsibility for global warming.. The diminished concern and sense of responsibility flies in the face of awareness campaigns about climate change, such as in the movies An Inconvenient Truth and Ice Age: The Meltdown and in the mainstream medias escalating emphasis on the trend.. The research was ...
​When it comes to empathy and sympathy, the problem is that many people cant seem to have either of them until awful shit happens to them as well. Maybe. Too many people are unwilling to make that mental, emotional leap to truly empathize with the unfortunate plight of others. No way we can initiate effective…
While these efforts are of monumental importance, theyre merely Band-Aids covering the wounds of privatization. Even before Trumps ascent to the presidency, the nature of internet oversight was historically laissez-faire, rendering the web an often predatory place ripe for commercial takeover. Governments have failed to regulate the internet as a public utility, furnishing it with unchecked invasive potential. Though the Federal Communications Commission (FCC) technically classified internet as a utility in 2015, it wasnt until late 2016 that the government barred ISPs from collecting such sensitive data as social-security numbers and healthcare information without explicit user consent--a law Americans now wont see come to fruition any time in the near future. The loss of such regulation is foreboding: these requirements were protocol for a communications utility; were a phone company to eavesdrop on a users call without that persons knowledge, it would be violating the law. Now, however, ...
Apathy and fatigue may be caused by thyroid problem or hormone imbalance. Apathy and fatigue in endometriosis is caused by the pressure of coping with any sort of pain that returns relentlessly every month, affecting her physical and emotional state.
The climate is changing. Great Lakes organizations and officials are trying to make sure restoration work is done with this in mind. But climate change remains
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A week or so ago, there was a large discussion on QuiltArt.com about copyright. Congress is debating the Orphan Works bill (there is an excellent article on this subject here) and the subject of Flickr.com came up.
As the U.S. military sets out to secure cities including Kandahar, it is relying far more heavily on Afghan forces than at any time in the past nine years, when the American mission focused mainly on defeating the Taliban in the countryside, rather than securing the population. But the Afghan forces are proving poorly equipped and sometimes unmotivated, breeding the same frustration U.S. troops felt in Iraq when they began building up security forces beset by corruption, sectarianism, political meddling and militia infiltration.. ...
It was comfortable in his bed, so he decided to stay there.. It was still comfortable the next day, because it was so soft.. It was still comfortable the next week, because it was so warm.. It was still comfortable the next month, because he couldnt feel anything at all.. ...
The peak of tolerance is most readily achieved by those who are not burdened with convictions, Alexander Chase, Perspectives (1966) Romans 1:26 For this reason God gave them over to dishonorable passions. For their women exchanged the natural sexual relations for unnatural ones, 1:27 and likewise the men also abandoned natural relations with women and were inflamed in their passions for one another
Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis are now recognized as core features of Alzheimer’s disease (AD), and there is a general consensus that greater symptom severity is predictive of faster cognitive decline, loss of independence, and even shorter survival. Whether these symptoms result from the same pathogenic processes responsible for cognitive decline or have unique etiologies independent of AD-associated neurodegeneration is unclear. Many structural and metabolic features of the AD brain are associated with individual neuropsychiatric symptoms or symptom clusters. In addition, many genes have been identified and confirmed that are associated with symptom risk in a few cases. However, there are no single genes strongly predictive of individual neuropsychiatric syndromes, while functional and structural brain changes unique to specific symptoms may reflect variability in progression of the same pathological processes. Unfortunately, treatment
Background: To study the extent to which neuropsychiatric symptoms (NPS) influence the cognitive and functional decline in frontotemporal degeneration (FTD) and Alzheimers disease (AD).Methods: We assessed the progression of NPS and their influence on cognitive and functional progression in a group of FTD (n = 36) and AD patients (n = 47) at two different stages of the disease (2.5 years). A standardized scale was used to assess NPS-the Columbia University Scale for Psychopathology in Alzheimers Disease (CUSPAD)-which tracks different symptoms including depression, psychotic symptoms, as well as sleep and conduct problems. In addition, in a subsample of patients (AD n = 14 and FTD n = 14), we analyzed another group of NPS by using the Neuropsychiatric Inventory (NPI). Cognitive declines were tracked by using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE), while functionality was tracked by using the Lawton scale and the Barthel Index.Results: The presence of NPS
It is generally agreed, mortality and morbidity rates, in patients operated on for ruptured intracranial aneurysm, strictly depend upon the state at admission. Nevertheless, a precise definition of surgical mortality is still not available. Even the term morbidity still remains rather controversial for the lack of accurate evaluation scales. The wide range of parameters, affecting the composition of sample and outcome of patients, such as age, blood at CT scan and atherosclerosis at angiography, makes harder a correct statistical analysis of mortality and morbidity. Moreover, the gap between bleeding and admission, the management and choice of treatment, the selection of unicentric or multicentric studies, the level of the hospital introduce even more striking bias errors. Recent papers reported concrete improvements obtained by means of both aggressive therapeutical behaviour and adequate intensive care management. Among factors, producing improvement of the overall outcome, have to be also ...
Performance artist Marina Abramovic's piece Measuring the Magic of Mutual Gaze is both art installation and science experiment, in which volunteers
Neuropsychiatric symptoms are commonly related to interferon alpha treatment. The paper summarises the current knowledge about their aetiology, course
Mental disorders can be classified into panic attack, Anxiety, Stress, Eating disorder, Depression, Anorexia, Obesity and post traumatic disorder
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It is not only possible to work with early onset Parkinsons disease, it is probable. Most people who were working prior to diagnosis continue to work for some period of time afterwards.. How long will I be able to work? This is usually the more difficult question to answer. The length of time each person continues working will depend on many different factors. Some will be related to the disease itself such as symptoms, medication side effects, or progression of the disease; others are likely to be environmental factors including the overall economy and your particular employer.. When it comes to Parkinsons Disease in the workplace, it can be helpful to think of symptoms as internal and external as motor symptoms and non-motor symptoms. External symptoms are those your employer, co-workers or clients may notice such as tremor, slowness, rigidity, facial mask, etc.and those that involve more internal processes such as fatigue, sleepiness, apathy or difficulty concentrating/multi-tasking. ...
Learn 200 innovative, problem-stopping strategies to prevent or stop social, emotional, behavioral, and K-12 classroom management problems like bad attitudes, cyberbullying, poor motivation, truancy, delinquency, work refusal, school failure, disrespect, defiance, depression, trauma and apathy. Plus, earn $45-$60 college credit and free clock hours from our live, online and on-site professional development courses.. ...
My moms only brother, my uncle, passed away unexpectedly in November of 2009. It was a devastating loss, as I have a very small family, and it was the first time I had lost someone close to me. It took a heavy emotional toll; because of the pain I felt, and because of the unimaginable sadness my mom and grandparents were enduring. I fell into a deep depression shortly thereafter, a combination of apathy, numbness and anger. About 8 months later, at the behest of my parents, I began to see a psychologist. After a few sessions of him getting to know my history, I was diagnosed with not only acute depression, but also cyclothymia, a less severe form of bipolar disorder. He suspected that I had lived several years of my early adulthood under a mild, persistent depression. I rejected that notion at the time, thinking it was just the way I am, but in hindsight Ive come to realize that he was right ...
Learn 200 innovative, problem-stopping strategies to prevent or stop social, emotional, behavioral, and K-12 classroom management problems like bad attitudes, cyberbullying, poor motivation, truancy, delinquency, work refusal, school failure, disrespect, defiance, depression, trauma and apathy. Plus, earn $45-$60 college credit and free clock hours from our live, online and on-site professional development courses.. ...
This mutation was identified in a Korean woman with AD and a family history of the disease (Kim et al., 2020). Her symptoms, starting at age 40, included memory impairment, visuospatial dysfunction, abulia, apathy, and depression. Moreover, shortly prior to death and three years after disease onset, the patient developed myoclonus and seizures. Her APOE genotype was APOE3/APOE3.. This variant was not found in the gnomAD database, nor in 500 Korean controls.. Neuropathology ...
It has anti-tumor, antiseptic, detoxifying, diuretic, antidepressant effects; helps with apathy, anxiety and has stimulating, as well as soothing properties. It attenuates headaches, stress, fatigue, induces relaxation. It is effective against overload of the entire organism, has an impact onto the balance of the body, supports and revives the condition to be able to withstand stress. It stimulates brain function, which helps in concentration. It supports the digestive tract, increases bowel movement and helps the body get rid of harmful toxins that occur in the metabolism. It also helps in constipation and insufficient digestion, increases urine production and eliminates excess water from the body. It can effectively help with tired and stiff muscles, especially during excessive physical activities. It promotes the immune system and fights free radicals, which are considered the cause of many diseases ...
Needle-like leaves and smells like pine is what this herb resembles. It has a powerful phytochemical called carnasol. What is great about it is its ability to detox cancer causing substances. Usually people add Rosemary in their soups, vegetable dishes and rice. Internally rosemary herb is used for depression, apathy, nervous exhaustion, headaches and migraines associated with nervous tension or feeling cold, poor circulation, and digestive problems associated with anxiety. Externally for rheumatism, arthritis, neuralgia, muscular injuries, wounds, dandruff, and scurf ...
Under the influence of alcohol, the brain cells begin to gradually die off. This leads to inhibition of intellectual functions. The transmission of impulses between nerve endings slowing down, which leads to changes in behavior, and the inhibition of mental functions. First, it affects the mood, you receive the apathy that is again trying to suppress alcohol because of the desire to experience the same euphoria.. In addition, there is a restructuring of the hormonal system, there are problems with the production of serotonin that in a few years leads to chronic depression, caused by irreversible damage to brain cells.. ...
By learning how to stimulate your own dopamine levels naturally, you wont have to feel depressed or suffer from anxiety, apathy, and fear.
Whos-Bored.com - Lets Make Politics F***ing Awesome!Whos-Bored.com is on a mission to break through the yawn barrier of British politics and turn apathy into action!Posted by Hands up whos...
Even if you have a CI process in place that runs all your tests and measures your code coverage, if you allow the build to stay broken, all of your work is for nothing. At the same time, breaking a build should not be a criminal offense. You want your team members to commit their changes frequently. When they do this its okay to have a build fail. You dont want developer to be overly cautious when committing, fearing a broken build. What you dont want is to let a build stay broken. If you leave a build broken for a long period of time, it is a symptom of apathy about keeping the code base at a high level of quality. You should also never commit changes to a broken build. You dont know what impact your changes will have on a systems that is not passing all of its tests. Also remember that the team has ownership of the code. Anyone can fix the build (that includes you), it doesnt have the person who broke the test.. There are lots of ways to enforce this. The easiest way is that tools like ...
Most of the weight of your dehydrated brain would come from fats also known as lipids. In the remaining brain matter, you would find proteins and amino acids, traces of micronutrient and glucose. The brain is, of course, more than just the sum of its nutritional parts, but each component does have a distinct impact on functioning, development, mood and energy. So that post-lunch apathy or late-night alertness you might be feeling that is simply the effects of food on your brain. Of the facts in your brain, the superstars are Omega 3 and 6. These fatty acids which have been linked to preventing degenerative brain conditions must come from our diets. So eating omega rich food like nuts, seeds and fatty fish is crucial to the creation and maintenance of cell membranes.. While omegas are good fats for your brain, long term consumption of other fats, such as tans and saturated fats may compromise brain health. Meanwhile, protein and amino acids the building block nutrients of growth and development ...
Green, Apathy, and Buckwild come up with fresh, funky ideas, R.A. responds with excellence, and sometimes a J-Zone-sized sense ... Apathy)". 2dopeboyz. 2013-02-20. Retrieved 2013-09-16. CS1 maint: discouraged parameter (link) "R.A. The Rugged Man: The ... The album's production was handled by Buckwild, Ayatollah, Apathy and Marco Polo among others. The first single from the album ... "The People's Champ", produced by Apathy, was released on February 20, 2013. On April 9, 2013, the music video was released for ...
"Dive Medicine, Chapter 1 (Instrumental Project) by Apathy on Apple Music". iTunes. "Get Rich or Get Recalled by Fredo on Apple ... ". "Perestroika , Apathy". "The Big Brother by DJ Kay Slay on Apple Music". iTunes. "Gorilla Warfare by Gorilla Zoe on Apple ...
Apathy). "Martha Moxley (R.I.P.)". Genius Lyrics. Archived from the original on July 26, 2019. Retrieved July 26, 2019. The ... Apathy) (July 26, 2019). "Martha Moxley (R.I.P.)". Genius Lyrics (lyrics). Archived from the original on July 26, 2019. ... In 2014, Connecticut-born rapper Apathy released a song entitled "Martha Moxley (Rest in Peace)" featuring a sample from George ...
Apathy. Young clerk let 2007. Gifford 2007, pp. 167-68. Lee, Lily; Westcott, Ben (June 3, 2019). "They faced down the tanks in ... "China's Youth post-Tiananmen: Apathy a fact or front?". CNN. June 4, 2009. Archived from the original on June 8, 2019. ...
"Apathy synopsis". Irish Metal Archives. Retrieved 25 March 2011. CS1 maint: discouraged parameter (link) "Apathy "Lack of ... The name Creation's Tears was the title of an Apathy song from their 1995 album entitled Inertia. Joe Gillespie guitars and ... A different version of the same track (written by Reynolds) appeared on Apathy's Inertia album (1995) but featured Laura ... "Ref to the "original" version of the song "Creation's Tears" from Apathy - Inertia". Creation's Tears. Archived from the ...
... is a benzamide,[12] derivative of morpholine,[103] which acts pharmacologically as a selective, reversible inhibitor of monoamine oxidase A (RIMA),[9] a type of monoamine oxidase inhibitor (MAOI), and increases levels of norepinephrine (noradrenaline), dopamine, and especially serotonin.[104][105] in neuronal cells as well as in synaptic vesicles; extracellular levels also increase which results in increased monoamine receptor stimulation and suppression of REM sleep, down regulation of 3-adrenoceptors. A single 300 mg dose of moclobemide inhibits 80% of monoamine oxidase A (MAO-A) and 30% of monoamine oxidase B (MAO-B), blocking the decomposition of norepinephrine, serotonin and, to a lesser extent, dopamine. There is also some evidence pointing towards moclobemide possessing neuroprotective properties.[8] There is no cumulative effect of moclobemide centrally when taken long-term.[8] With long-term use of moclobemide, there is a significant down-regulation of B-adrenoceptors.[8] ...
"Electors' Apathy". The Sydney Morning Herald. National Library of Australia. 16 December 1935. p. 12. Retrieved 25 March 2013 ...
... apathy etc. De Sanctis, however, understands that the catatonia of a 3-year-old girl cannot have the same pathogenesis as ...
Seidensticker, K. J.; Möhlmann, D.; Apathy, I.; Schmidt, W.; Thiel, K.; et al. (February 2007). "Sesame - An Experiment of the ...
Fitzgerald, Mary (30 September 2010). "Ireland's apathy". The Guardian. London. As soon as Ireland's finance minister Brian ...
CS1 maint: discouraged parameter (link) Banks, Adam (September 20, 2010). "Athletic apathy". McGill Daily. Retrieved January 19 ...
"Mortal Apathy?". The New York Times. Archived from the original on 2013-10-03. Retrieved 15 February 2021. Rignall, Jaz (1 ...
Sajner, Josef (1970). "Stephan Apathy". Dictionary of Scientific Biography. 1. New York: Charles Scribner's Sons. pp. 176-177. ...
"Timeshares - Bearable (re-issue) (Dead Broke Rekerds, 2016)". Apathy & Exhaustion. January 31, 2017. Retrieved May 16, 2019. " ...
Balakrishnan, Angela (3 May 2007). "Voter apathy? Here's the Sensible solution". The Guardian. Retrieved 18 February 2010. ...
Horwitz, Jeremy (8 July 2002). "Mortal Apathy?". The New York Times. Archived from the original on 2013-10-03. Retrieved 15 ...
"; "Ode to Apathy"; "Ode to Duel" "Laura Maria" [Mary Robinson], "Ainsi va le Monde, A Poem inscribed to Robert Merry"; "Ode to ...
"Alternatives to Apathy". The Saturday Review. pp. 27-32. ISSN 0036-4983. Davids, Leo (1970). "Rev. of People or Personnel and ...
They are most noted for their 2020 album Glory, Glory! Apathy Took Helm!, which received a Juno Award nomination for Heavy ...
Apathy Took Helm! Rufus Wainwright, Unfollow the Rules - July 10 Colter Wall, Western Swing & Waltzes and Other Punchy Songs - ...
Horwitz, Jeremy (July 8, 2002). "Technology: Mortal Apathy?". The New York Times. Retrieved March 4, 2012. Chris Kohler (2005 ...
"Pierre Lapointe". Apathy is Boring. Archived from the original on 26 May 2015. Retrieved 4 May 2015. "Pierre Lapointe : "La ...
ISBN 978-1-4766-4176-8. Horwitz, Jeremy (8 July 2002). "Technology: Mortal Apathy?". The New York Times. Rignall, Jaz (1 ...
"Honkey Kong - Apathy > Overview". AllMusic. Rovi Corporation. Retrieved August 26, 2012. "The Mushroom Cloud Effect - Adil Omar ...
"Apathy" Scoe 00. "Thank You (Remix)" (featuring Kendrick Lamar and Slim the Mobster) Bambu - One Rifle Per Family 13. "Boom" ...
Apathy, S (1896). Die Mikrotechnik der thierischen Morphologie. Braunschweig. "wholemount - Wiktionary". en.wiktionary.org. ...
"Apathy and Exhaustion". Allmusic. Retrieved 2010-01-19. "Apathy and Exhaustion". Fat Wreck Chords. Retrieved 2010-01-19. Spano ... This was followed by the full-length album Apathy and Exhaustion, released in 2002. The album spawned the band's second music ...
"Apathy Eastern Philosophy". exclaim.ca. "Apathy - Eastern Philosophy - IGN" - via www.ign.com. "RapReviews.com Feature for ... Eastern Philosophy is the first official album by rapper Apathy. After years of deals in limbo, Apathy was finally able to ... 8 Apathy - track 7, 12 DJ Cheapshot - track 8 Exact Beats - track 11 8th & Vertygo - track 13 Executive Producer: Apathy ... www.amazon.com/Eastern-Philosophy-Apathy/dp/B000BJNTTO HAMAD, MICHAEL. "DJ ChumZilla Debuts New Album 'Get Off The Earth' On ...
"Deplores Voter Apathy; Miss Maude Wetmore Sees Party Government in Danger". The New York Times. December 14, 1927. p. 14 - via ...
"Apathy for Beginners". Visit Wagga. Archived from the original on 15 July 2019. Retrieved 15 July 2019.. ... There is also an Australian group who performs, named "Apathy for Beginners" Psychosomatic illness Brink, Susan. "In Sweden, ... apathy, non-communication, and loss of bodily functions. There are also signs of severe long-term stress which are worsened by ...
Although not a well-established psychological syndrome among educators, assessment apathy can be serious. For example, consider ...
... By Katie Ash - July 09, 2008 1 min read ...
"Apathy Matters - Apathy and Depression: Psychiatry may not care about apathy, but that doesnt mean you shouldnt Archived 20 ... The Dimensional Apathy Scale (DAS) is a multidimensional apathy instrument for measuring subtypes of apathy in different ... As a response, apathy is a way to forget about these negative feelings.[citation needed] This type of common apathy is usually ... The cure for apathy is comprehension." Apathy is a normal way for humans to cope with stress. Being able to "shrug off" ...
Army of the Pharaohs discography Get Busy Committee discography "Perestroika by Apathy & O.C. on Apple Music". iTunes. "Apathy ... The discography of Apathy, an underground rapper from Connecticut, USA. He released several studio albums, EPs and mixtapes. ...
... which researchers say is the first evidence of a biological basis for apathy. ... Apathy in older adults linked to increased brain shrinkage Older people who have apathy - a lack of interest or emotion - are ... Though apathy is traditionally viewed as an attitude or outlook, the neuroscientists say their results suggest it is actually ... Does reading the rest of this article feel like too much work? If so, your apathy may be down to specific brain differences, ...
Apathy Rules Among Brazils Youth Voters Brazil is one of a handful of places in the world where the voting age is just 16. ... But as the country gears up for presidential elections Sunday, apathy prevails among youth in Brazil, where the voting age is ... Palma de Jorge says now the apathy of many young people is due largely to Brazils political and economic stability -- which ...
Ive been involved with my sweety-pie since she was 99, although not directly in her day-to-day rehabilitation until she was given up by a professional rehab center about 19 months ago. Her visiting nurse showed up. She was in a room alone, tied to the bed with no wheelchair and only a 25 watt light in the room. She was only being fed warm ensure. The aides would go to another part of the house and watch television all day. The nurse told me Shes 100 years old. She cant possibly benefit from visual stimulation. Let her die in dignity. It was at that point I said to this creature R.N. things I cant repeat on this board. The aides were criminals who stole her jewelry and wedding ring and who I witnessed forcing scalding soup into her mouth. Yup. I fired that one. And they would show up with colds and deliberately cough in her face. A witnessed event. And they threw out her favorite dolls. And tied her water bottle to the bedrail just out of her reach. If this was 1814 I would have called out ...
... predominantly minority schools-soon become disillusioned and discouraged in the face of widespread student apathy. ...
... Roberta Semprini,1 Adele Lubrano,1 Giulia Misaggi,1 and Alessandro Martorana1,2 ... R. S. Marin, B. S. Fogel, J. Hawkins, J. Duffy, and B. Krupp, "Apathy: a treatable syndrome," Journal of Neuropsychiatry and ... C. U. Onyike, J. M. E. Sheppard, J. T. Tschanz et al., "Epidemiology of apathy in older adults: the cache county study," ... R. Levy and B. Dubois, "Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits," Cerebral Cortex, ...
Learn about the possible causes of apathy, depression and anxiety and how these psychological conditions might affect the ... Apathy. One of the reasons that people with dementia are thought to develop apathy is damage to the brains frontal lobes. ... Experiencing apathy, and causes of depression and anxiety. Many of the things that can cause people to feel depressed can also ... A person experiencing apathy alone will not have symptoms of low mood, more a feeling of being without energy or spark. ...
Ukraine has entered the last week before the January 17 presidential election with many disappointed voters and attempts to alter the vote at local election commissions.
Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T ... Apathy and cortical atrophy in Alzheimers disease.. Tunnard C1, Whitehead D, Hurt C, Wahlund LO, Mecocci P, Tsolaki M, Vellas ... Apathy is mediated by frontocortical structures but this is specific to the left hemisphere at least for patients in the mild ... We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had ...
Get the Apathy Cream. A solid mask of Apathy Cream has been applied to Asoks face. Wally says, Hell be okay when the apathy ... 38 Results for Apathy. View 1 - 10 results for apathy comic strips. Discover the best "Apathy" comics from Dilbert.com. ... Tags #apathy, #telephones, #get tech support, #audio menu, #tech support, #user manuals, #hate customers, #apathy thing ... Tags #apathy, #executives, #work ethic, #enginner, #no budget, #emailed, #ceo, #social network, #global supply chain ...
The Cost Of Apathy. By Roger Anghis,2017-08-06T01:32:32-04:00August 6th, 2017, ... What we are seeing not just is Washington, D.C. but across the nation is the results of fifty plus years of apathy of the ... Will it eventually happen? Im afraid yes simply because of apathy. We no longer teach the greatness of America and unless the ...
As the figures in the chart show, only 34 per cent of YouGovs respondents said they would like to be wed in a church or some other place of religious worship - a synagogue, mosque or temple. Nearly double that proportion, 63 per cent, would prefer not to be married in a place of worship at all (23 per cent) or else shrugged their shoulders and said indifferently that they "would not mind one way or the other" (40 per cent).. ...
Home » Magazine » National » No Cure For Encephalo-Apathy No Cure For Encephalo-Apathy. True, remedy is non-existent for the ... Dr R.N. Singh August 17, 2017 00:00 IST No Cure For Encephalo-Apathy outlookindia.com ...
... Share this:. *Click to share on Facebook (Opens in new window) ...
Political Apathy or Energy?. By Katie Ash on July 9, 2008 11:50 AM ...
The link between apathy and depression as well as apathy and impulsivity was explored in two contributions. D. Ahearn et al. ... The papers in this issue encompass a broad spectrum of clinical aspects of apathy with a clear overarching theme of apathy as ... the overlap between apathy and depression, and the application of new technologies in the management of apathy in the nursing ... the degree of overlap between depression and apathy was dependent on the method of assessment of apathy. The assessment and ...
Lettin Apathy get on the mic Thats like unleashing a f**king atom... ... Apathy Just Begun lyrics & video : [Funkmaster flex sample] [Celph Titled] Yo what the f**k are yall thinkin ... APATHY. Just Begun Lyrics. [Funkmaster flex sample]. [Celph Titled]. Yo what the f**k are yall thinkin. Lettin Apathy get on ... Yo Apathy rip the spines outta these mutherf**kers. [Apathy]. Im gonna spit an incredible verse. Your headll reverse and ...
A prime example of apathy and ignorance was to be seen at an open forum held in Battlement Mesa last Saturday with Rep. Bob ... Apathy is what will eventually have us enslaved.. What would our state representative have taken away from this puny gathering ... A prime example of apathy and ignorance was to be seen at an open forum held in Battlement Mesa last Saturday with Rep. Bob ... Letter: Apathy and ignorance. Letter To The Editor Letter-to-the-editor , ...
"Weve killed despair across the country and weve killed apathy.". The Occupy Movement has spread across the country and around ... Michael Moore joined the protesters in Oakland this week to congratulate them on successfully killing apathy in America. ...
A review of the literature on apathy, hypothalamic-pituitary-end organ axis dysfunction, and treatment for apathy syndrome is ... A review of the literature on apathy, hypothalamic-pituitary-end organ axis dysfunction, and treatment for apathy syndrome is ... Apathy Syndrome and Pituitary microadenoma?? Blue727 I just found this article from The Journal of Neuropsychiatry & Clinical ... I hope that more doctors now are thinking of hormone dysfunction as a cause of anxiety and apathy. If only they would refer ...
Findings from a recent study suggest that older adults who develop severe apathy over time may be at a higher risk of also ... "Apathy can be very distressing for family members, when people no longer want to get together with family or friends or dont ... Apathy could be an indicator of dementia, study finds. Researchers say losing interest in activities that are usually ... "In fact, we believe that apathy may be a very early sign of dementia and it can be evaluated with a brief questionnaire." ...
Apathy. Published by the European Parkinsons Disease Association (EPDA), February 2018. Apathy is a symptom of Parkinsons. ... Apathy. Published by the Parkinsons Foundation. This short webpage distinguishes between depression and apathy. It includes ... The conversation distinguishes apathy from depression. The focus is on how apathy affects both the person with PD and those who ... It provides three rating scales to help diagnose apathy in Parkinsons, medication and counseling options to treat apathy, ...
apathy with Grammar Rules from the Writers Digest editors, including their differences and when they might overlap. ... Apathy (Grammar Rules). Learn when youre using empathy vs. sympathy vs. apathy with Grammar Rules from the Writers Digest ... As such, apathy and sympathy cannot co-exist. However, empathy and apathy could, because a person could understand another ... Apathy is a complete lack of feeling or concern for something or someone. It's not malicious or angry; rather, it's ...
Why Apathy in Alzheimers Matters. Am J Psychiatry. 2018 Feb 01;175(2):99-100 Authors: Sultzer DL PMID: 29385833 [PubMed - in ... Why Apathy in Alzheimers Matters. Am J Psychiatry. 2018 Feb 01;175(2):99-100 Authors: Sultzer DL PMID: 29385833 [PubMed - in ...
Apathy towards poachers widespread in worlds marine protected areas A new study has found that nearly half of fishers from ... Apathy towards poachers widespread in worlds marine protected areas. ARC Centre of Excellence in Coral Reef Studies ... "The bad news is that apathy towards poaching in marine protected areas is widespread," said co-author Dr Michele Barnes, "but ...
Its not true that no one worries about terrorists attacking chemical plants, its just that our politics seem to leave us unable to deal with the threat.. Toxins such as ammonia, chlorine, propane and flammable mixtures are constantly being produced or stored in the United States as a result of legitimate industrial processes. Chlorine gas is particularly toxic; in addition to bombing a plant, someone could hijack a chlorine truck or blow up a railcar. Phosgene is even more dangerous. According to the Environmental Protection Agency, there are 7,728 chemical plants in the United States where an act of sabotage - or an accident - could threaten more than 1,000 people. Of those, 106 facilities could threaten more than a million people.. The problem of securing chemical plants against terrorism - or even accidents - is actually simple once you understand the underlying economics. Normally, we leave the security of something up to its owner. The basic idea is that the owner of each chemical plant ...
As a result, the most popular political sentiment among Hungarians appears to be apathy. ...
  • P. Njomboro and S. Deb found that in a sample of patients with acquired brain injury, the degree of overlap between depression and apathy was dependent on the method of assessment of apathy. (hindawi.com)
  • This short webpage distinguishes between depression and apathy. (stanford.edu)
  • The purpose of the present study was to examine the independent influence of symptoms of depression and apathy, two of the most common neuropsychiatric symptoms in Parkinson's disease (PD), on executive functioning and memory in PD patients using measures designed to discriminate between these symptoms. (unboundmedicine.com)
  • Hierarchical regression analyses were conducted to evaluate the degree of influence of depression and apathy on cognitive function. (unboundmedicine.com)
  • While depression and apathy are also associated, they are not synonymous. (healthjockey.com)
  • As we celebrate this most American of holidays, our Republic is sick with 2 endemic issues: Lack of Civility and Voter Apathy. (journal-news.net)
  • Voter apathy is an issue we, the people, must address. (journal-news.net)
  • Olukolade confirmed that the attacks were used to distribute materials aimed at causing voter apathy amongst Nigerians resident in the state. (channelstv.com)
  • Recently INEC commissioned a report on voter apathy and the 2011 general elections. (channelstv.com)
  • Some quarters were not satisfied with the result from the report as the claim that poverty is the source for voter apathy. (channelstv.com)
  • what methodolody was used to reach the conclusion that poverty actually was responsible voter apathy? (channelstv.com)
  • Mike Igini, a Resident Electoral Commissioner for INEC for Cross River gave his view on voter apathy. (channelstv.com)
  • A report commissioned by the Independent Electoral Commission (INEC) on the root cause of voter apathy in the 2011 general elections in the country has come under heavy criticisms. (channelstv.com)
  • One of the critics of the report and Human Rights lawyer, Femi Aborisade questioned the data provided by INEC in its voter apathy survey. (channelstv.com)
  • UMKC associate dean of the College of Arts and Sciences, Beth Vonnahme, defines voter apathy as nonparticipation caused by feeling "turned off" of the political process. (umkc.edu)
  • Armed only with excellent electoral sleuthing skills, the commission will battle the epidemic threatening the legitimacy of LA's democracy-voter apathy-and explore ways to boost voter participation. (publicceo.com)
  • Pathological apathy, characterised by extreme forms of apathy, is now known to occur in many different brain disorders, including neurodegenerative conditions often associated with dementia such as Alzheimer's disease, and psychiatric disorders such as schizophrenia. (wikipedia.org)
  • Apathy and cortical atrophy in Alzheimer's disease. (nih.gov)
  • Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimer's disease (AD), associated with greater functional decline and caregiver distress. (nih.gov)
  • Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) is a Phase III, placebo-controlled, masked, 6 month, multi-center randomized clinical trial sponsored by National Institutes of Aging involving 200 participants with Alzheimer's disease (AD). (clinicaltrials.gov)
  • Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimer's Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months. (clinicaltrials.gov)
  • ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimer's disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. (clinicaltrials.gov)
  • ADMET will enroll 60 patients with Alzheimer's disease (AD) and significant apathy from outpatient, nursing home, and assisted living facilities along with their primary caregiver. (clinicaltrials.gov)
  • While only about 1 percent of the general healthy population suffers from apathy, the condition affects up to 70 percent of those with moderate Alzheimer's disease. (alzinfo.org)
  • Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer's Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. (nih.gov)
  • Apathy is a common behavioral problem in Alzheimer's disease. (nih.gov)
  • The authors' objective was to study the effects of methylphenidate on apathy in Alzheimer's disease. (nih.gov)
  • Methylphenidate improved apathy in a group of community-dwelling veterans with mild Alzheimer's disease. (nih.gov)
  • Addressing Possible Effects of Sleep Apnea in a Study of Methylphenidate for Apathy in Alzheimer's Disease: Response to Kolla and Mansukhani. (nih.gov)
  • Methylphenidate and Apathy in Alzheimer's Disease: Is Sleep Apnea a Confounding Effect? (nih.gov)
  • LOS ANGELES, Aug. 05, 2021 (GLOBE NEWSWIRE) -- Praxis is proud to announce to be the recipient of a Fast-Track SBIR award to develop treatment for apathy in Alzheimer's Disease. (yahoo.com)
  • PRX-P4-003 is a new chemical entity (US Patent 10,662,146) designed by Praxis to be an abuse resistant, once-a-day medicine to treat apathy caused by Alzheimer's disease as well as other diseases requiring dopaminergic stimulant activity. (yahoo.com)
  • For people with Alzheimer's disease , apathy is one of the most prevalent behavioral symptoms, affecting 50 to 70 percent of those diagnosed, according to some studies. (uhhospitals.org)
  • Currently, there are no proven treatments available for patients who display significant signs of apathy associated with Alzheimer's disease. (uhhospitals.org)
  • found that in Parkinson's disease, apathy and impulsivity might overlap and that specific phenomenological profiles within the behavioural syndromes were associated with particular clinical phenotypes. (hindawi.com)
  • This post in the Foxfeed Blog explains apathy is a non-motor symptom of Parkinson's disease, the symptoms, potential consequences, diagnosis, behavioral adjustments to help live with apathy and medication options. (stanford.edu)
  • Apathy and Parkinson's Disease, Does it Really Matter? (stanford.edu)
  • This short article emphasizes Parkinson's disease is no longer just a movement disorder, but symptoms, like apathy, require active management. (stanford.edu)
  • Fatigue and apathy are common non-motor symptoms in Parkinson's Disease (PD). (asaging.org)
  • Likewise, apathy occurring in Parkinson's disease could be interpreted as secondary to the loss of spatial and temporal focalization of the signals transferred to the frontal cortex. (nih.gov)
  • In Parkinson's disease, reduced pupillary modulation by incentives was predictive of apathy severity, and independent of motor impairment and autonomic dysfunction as assessed using overnight heart rate variability measures. (nih.gov)
  • Apathy is also a feature of other nervous system disorders like Parkinson's disease as well as mental health disorders like depression (which is also common in Alzheimer's). (alzinfo.org)
  • A new scientific study suggests that apathy shown by a person with Parkinson's disease is a sign that the condition is worsening. (barchester.com)
  • Although not a well-established psychological syndrome among educators, assessment apathy can be serious. (edweek.org)
  • The papers in this issue encompass a broad spectrum of clinical aspects of apathy with a clear overarching theme of apathy as an important behavioural syndrome which warrants careful study of its features, diagnosis and management. (hindawi.com)
  • Apathy Syndrome and Pituitary microadenoma? (medhelp.org)
  • When the diagnosis of apathy syndrome was considered and treatment implemented, the patients' condition improved. (medhelp.org)
  • A review of the literature on apathy, hypothalamic-pituitary-end organ axis dysfunction, and treatment for apathy syndrome is included. (medhelp.org)
  • I'm curious about this Apathy Syndrome and how they might treat it differently. (medhelp.org)
  • For example, Robert S. Martin, MD, defined apathy as a syndrome of primary motivational loss that is not attributable to emotional distress, intellectual impairment, or diminished level of consciousness . (psychiatrictimes.com)
  • The past few decades have seen growing interest in the neuropsychiatric syndrome of apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed behaviour. (bmj.com)
  • Finally, we relate these findings to clinical apathy, demonstrating the homologies between this basic neuroscience work and emerging behavioural and physiological evidence from patient studies of this syndrome. (bmj.com)
  • This description resonates with much of the phenotype of apathy, a neuropsychiatric syndrome conceptualised as a loss of motivation that manifests in reduced goal-directed behaviour 1 2 -see box 1 for key definitions. (bmj.com)
  • Apathy is a complex syndrome that is composed of different subtypes of demotivation. (uea.ac.uk)
  • The data obtained were also correlated with behavioral/cognitive tests and scales assessing global cognitive efficiency, apathy, cognitive disinhibition, frontal syndrome, depression and anxiety. (frontiersin.org)
  • Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. (bmj.com)
  • There is no consensus on diagnostic criteria for apathy as a syndrome. (bmj.com)
  • In summary, apathy is increasingly recognised as a common behavioural syndrome associated with neuropsychiatric disorders. (bmj.com)
  • There is however no consensus as to whether apathy should be considered a symptom of major neuropsychiatric disorders, or as a syndrome in its own right. (bmj.com)
  • In addition, critical questions regarding the phenomenology of apathy and the syndromal validity of this construct, as well as the relationship between apathy and similar concepts, such as abulia, the autoactivation deficit, athymormia, the negative syndrome and psychic akinesia, still remain unanswered. (bmj.com)
  • In addition it is now appreciated that apathy is unlikely to be a unitary construct but is more likely to be a syndrome that might result from dysfunction in several different component decision-making mechanisms ( Levy and Dubois, 2006 ). (pubmedcentralcanada.ca)
  • To HAVE YOU: Weed tas a treatment for Apathy? (cnn.com)
  • There is no approved treatment for apathy in dementia today. (yahoo.com)
  • Also meaning "absence of passion," "apathy" or "insensibility" in Greek, the term apatheia was used by the Stoics to signify a (desirable) state of indifference towards events and things which lie outside one's control (that is, according to their philosophy, all things exterior, one being only responsible for one's own representations and judgments). (wikipedia.org)
  • Blogger Maria De León, retired neurologist and person with Parkinson's, distinguishes between apathy and indifference. (stanford.edu)
  • Apathy is a feeling of indifference or lack of interest or motivation in activities. (stanford.edu)
  • Those with apathy, on the other hand, tend to show emotional indifference rather than feeling depressed. (alzinfo.org)
  • It will be a slow ________ from apathy, indifference, and undernourishment. (thefullwiki.org)
  • Apathy (also called impassivity or perfunctoriness ) is a state of indifference , or the suppression of emotions such as concern , excitement , ________ and passion . (thefullwiki.org)
  • Depression is characterized by strong negative emotions and feelings of sadness and hopelessness, while apathy is defined as a chronic state of indifference or lack of emotion. (uhhospitals.org)
  • The clinical signs grouped under the concept of apathy are a common feature of prefrontal and basal ganglia lesions or dysfunctions and can therefore help to improve our understanding of the functional anatomy of the prefrontal-basal ganglia system. (nih.gov)
  • The aim of this study was to examine the concept of apathy as it is currently used in neurology and psychiatry, by review of the literature and conceptual analysis. (bmj.com)
  • The contemporary concept of apathy could not be more different than the Stoic. (bmj.com)
  • However, they add that their findings do not account for apathy in everyone, but rather, they provide more information about brain processes involved in "normal motivation. (medicalnewstoday.com)
  • Apathy describes a lack of interest, enthusiasm or motivation. (stanford.edu)
  • According to an international consensus criterion, apathy is defined as a disorder of motivation in which the symptoms are present for at least 4 weeks. (psychiatrictimes.com)
  • Apathy causes a general lack of motivation and interest, as well as a dampening of emotional expression. (michaeljfox.org)
  • Apathy is a lack of motivation towards goal directed behaviours and has been reported as occurring in up to 50 per cent of people living with motor neurone disease (MND). (uea.ac.uk)
  • Our previous research showed Initiation apathy (a lack of motivation for generation of thoughts) is characteristic in MND and associates with performance on certain neuropsychological tasks. (uea.ac.uk)
  • This research is of a cross-sectional design looking at associates of apathy subtypes in people living with MND and a further longitudinal design, with people with MND and their families being asked to take part in four repeat interviews every three months for a year exploring any changes in motivation, behaviour, cognition, quality of life and well-being. (uea.ac.uk)
  • One of the most common is apathy, or loss of motivation, and the condition seems to have a biological basis. (alzinfo.org)
  • Those with mild cognitive impairment, a form of serious memory loss that sometimes precedes Alzheimer's, are also more likely to exhibit the loss of motivation that occurs with apathy. (alzinfo.org)
  • Those affected by apathy show a lack of motivation and often withdraw from social and other activities. (alzinfo.org)
  • Apathy is mostly defined as a disorder of motivation, and operationalised as diminished goal oriented behaviour and cognition. (bmj.com)
  • While many people associate apathy with a lack of passion or motivation, it is technically defined as the absence of emotion. (addicted2success.com)
  • If you know you are dealing with apathy, it is time to make a change and it is time to turn that apathy into positive motivation. (addicted2success.com)
  • If you want to turn your apathy into motivation to succeed, the number one thing you can do is to stop complaining. (addicted2success.com)
  • How will you turn apathy to positive motivation? (addicted2success.com)
  • Concomitantly, there was an improvement in the patient's clinical state, with reduced apathy, greater motivation and increased social interactions. (pubmedcentralcanada.ca)
  • The profound lack of motivation seen in patients with significant apathy limits their ability to carry out the simplest activities of daily living, thus increasing the demands made on caregivers. (uhhospitals.org)
  • We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. (nih.gov)
  • Now, a new study conducted by researchers from the American Academy of Neurology has discovered a new symptom that could increase consumers' risk of developing Alzheimer's: apathy. (consumeraffairs.com)
  • Apathy is a symptom of Parkinson's. (stanford.edu)
  • Firsthand accounts from those coping with apathy as a symptom of PD demonstrate that lifestyle changes and support go a long way toward maintaining a good quality of life despite feelings of apathy. (stanford.edu)
  • 8 Apathy is also the most frequently reported behavioral symptom among individuals with dementia. (psychiatrictimes.com)
  • Although there are symptom overlaps, apathy and depression are two separate and distinct diagnoses. (uhhospitals.org)
  • He went on to say that the charity's own research had found apathy to be a common symptom, while understanding why people with the condition may be apathetic may help carers. (barchester.com)
  • ADMET 2 is designed to examine the efficacy and safety of methylphenidate as treatment for clinically significant apathy in AD participants. (clinicaltrials.gov)
  • ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimer's dementia. (clinicaltrials.gov)
  • Two hundred patients with clinically significant apathy will be recruited and each will undergo a series of physical, cognitive and neuropsychiatric tests at the beginning of the study and at monthly follow-up visits. (uhhospitals.org)
  • 16 Another study examined regions of cortical thinning and CSF biomarkers (amyloid-β ١-٤٢, total tau, and phosphorylated tau) among 3 groups-clinically normal elderly individuals, individuals with mild cognitive impairment, and individuals with mild AD dementia with apathy-and found that reduced baseline inferior temporal cortical thickness was predictive of increasing apathy over time. (psychiatrictimes.com)
  • The specific topics represented by the papers range from an exploration of the phenomenology of apathy and the manifestation of apathy in different neurodegenerative conditions, the overlap between apathy and depression, and the application of new technologies in the management of apathy in the nursing home settings. (hindawi.com)
  • Older adults with higher baseline apathy, as well as those with increasing apathy over time, were at higher risk of developing dementia. (neurosciencenews.com)
  • The Apathy in Dementia Methylphenidate Trial (ADMET), funded by the National Institute of Aging, is a Phase II, placebo-controlled, masked, 3-center randomized clinical trial. (clinicaltrials.gov)
  • Apathy due to the disruption of 'emotional-affective' processing refers to the inability to establish the necessary linkage between emotional-affective signals and the ongoing or forthcoming behavior. (nih.gov)
  • Apathy due to the disruption of 'cognitive' processing refers to difficulties in elaborating the plan of actions necessary for the ongoing or forthcoming behavior. (nih.gov)
  • The neural mechanisms of apathy are postulated to involve the brainstem and forebrain circuits that regulate goal-directed behavior. (glutenfreeworks.com)
  • The prevailing attitudes of overconfidence and apathy may be to blame for what is a notable discrepancy among survey respondents in understanding what responsible security behavior looks like and actually engaging in that behavior. (securitymagazine.com)
  • Apathy affects interpersonal behavior with pervasive negative consequences," says Alan Lerner, MD , Director of the Brain Health & Memory Center at UH Cleveland Medical Center . (uhhospitals.org)
  • How to Deal With Apathy at the Workplace" accessed March 22, 2018. (chron.com)
  • FentaNYL patch fatalities linked to 'bystander apathy. (ahrq.gov)
  • One of the reasons that people with dementia are thought to develop apathy is damage to the brain's frontal lobes. (alzheimers.org.uk)
  • Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and ventrolateral frontal regions, than those without apathy symptoms. (nih.gov)
  • 7 Among individuals with AD, apathy is associated with an increased neurofibrillary tangle burden in the parahippocampal, frontal, and parietal regions, in addition to the anterior cingulate gyrus. (psychiatrictimes.com)
  • Emerging evidence indicates that the severity of apathy is also associated with amyloid plaque burden, especially in bilateral frontal cortices and the right anterior cingulate gyrus along with other cortical areas of the brain . (psychiatrictimes.com)
  • Apathy is also consistently associated with neuroimaging changes in specific medial frontal cortex and subcortical structures, suggesting that disruption of a common systems-level mechanism may underlie its development, irrespective of the condition that causes it. (bmj.com)
  • Previous morphology studies have demonstrated that apathy in patients with schizophrenia is associated with reduced frontal grey matter (GM). (ovid.com)
  • Apathy scores were negatively correlated with several GM clusters in frontal regions, including the frontal inferior operculum and the left dorsal anterior cingulate cortex. (ovid.com)
  • We replicated previous associations between reduced frontal GM and apathy in patients with schizophrenia. (ovid.com)
  • This 2-page fact sheet (PDF) explains there are three forms of apathy, that it is distinct from depression, and how it can be diagnosed. (stanford.edu)
  • This short webpage provides specific tips to increase participation in needed and desired activities in spite of the symptoms of apathy. (stanford.edu)
  • The Apathy Evaluation Scale-Self-Rating and select items of the Beck Depression Inventory II were used to assess symptoms of apathy and depression, respectively. (unboundmedicine.com)
  • Results revealed that symptoms of apathy, but not depression, were significantly and negatively associated with executive functioning. (unboundmedicine.com)
  • These important nosological problems, as well as issues related to the assessment of apathy, will be the focus of the present review article. (bmj.com)
  • There is discussion about whether an emotional dimension should form part of the definition of apathy. (bmj.com)
  • Current psychiatric classification systems do not provide a definition of apathy. (bmj.com)
  • 3 In addition, the underlying mechanism(s) responsible for apathy may be seen as dysfunctions occurring at the level of elaboration, execution, and control of goal-directed behaviors. (psychiatrictimes.com)
  • Correlations and hierarchical regressions were conducted to investigate the relationships between apathy, depression, and cognitive function. (unboundmedicine.com)
  • The study, published on 11 July in the Journal of Neurology, Neurosurgery & Psychiatry is the first to examine the relationships between apathy, depression, and dementia in individuals with cerebral small vessel disease (SVD). (neurosciencenews.com)
  • Apathy occurs frequently, and with substantial impact on quality of life, in a broad range of neurological and psychiatric conditions. (bmj.com)
  • In spite of a lack of a proper definition, "apathy" is increasingly diagnosed in patients with neurological and psychiatric conditions. (bmj.com)
  • In a clinical context, the term "apathy" refers to a clustering of behavioural and emotional symptoms that manifests as diminished interest and involvement in normal purposeful behaviour, diminished emotional responsiveness, and a lack of initiation and drives to complete nonroutine activities. (hindawi.com)
  • Their findings suggest that the different anatomical substrates of the respective dementia types may drive the different clinical expression of apathy, which may, in turn, inform the diagnosis of the dementia type. (hindawi.com)
  • In parallel with this growing recognition of the clinical importance of apathy, significant advances have been made in understanding normal motivated behaviour in humans and animals. (bmj.com)
  • Furthermore, determining to what extent apathy subtypes are associated with quality of life will help inform the design of behavioural interventions using domains where patients do not have motivational difficulties, linking to the MND research program and the development of the MiND Toolkit project at the University of East Anglia and the Clinical Audit Research Evaluation-MND (CARE-MND) platform at the University of Edinburgh. (uea.ac.uk)
  • However, despite its clinical importance, there remains limited understanding of mechanisms underlying apathy. (nih.gov)
  • These findings suggest that reward insensitivity may be a contributory mechanism to apathy and provide potential new clinical measures for improved diagnosis and monitoring of apathy.media-1vid110.1093/brain/aww188_video_abstractaww188_video_abstract. (nih.gov)
  • Apathy is one of the six clinical criteria for the behavioral variant of frontotemporal dementia (bvFTD), and it is almost universal in this disease. (frontiersin.org)
  • A structured clinical interview and a proposal for diagnostic criteria for apathy in dementia have been recently validated. (bmj.com)
  • Other relevant issues, such as epidemiology, demographic and clinical correlates, and putative mechanism of apathy in specific neuropsychiatric conditions, will not be directly addressed. (bmj.com)
  • The primary outcome for apathy (Apathy Evaluation Scale-Clinician) and secondary outcomes for cognition (Mini-Mental State Examination, Modified Mini-Mental State Examination), functional status (activities of daily living, instrumental activities of daily living), improvement and severity (Clinical Global Impressions Scale [CGI]), caregiver burden (Zarit Burden Scale), and depression (Cornell Scale for Depression in Dementia) were measured at baseline and at 4, 8, and 12 weeks. (nih.gov)
  • Why is America the isolated case study of this strange domestic malady that may best be summed-up as: clinical, terminal apathy? (veteranstoday.com)
  • Based on promising, preliminary results from a previous clinical trial, the researchers are investigating the benefits of methylphenidate (commonly known as Ritalin) drug therapy for Alzheimer's-related apathy. (uhhospitals.org)
  • ADMET 2 will enroll participants from real world settings such as outpatient, nursing home, and assisted living facilities and will examine the effects of methylphenidate on apathy and cognition. (clinicaltrials.gov)
  • ADMET has 80% power to detect a difference of at least 3.3 in change in the Apathy Evaluation Scale scores between the two treatment groups. (clinicaltrials.gov)
  • We are honored to receive this highly competitive SBIR award from National Institute of Aging as we work continuously to build upon the pioneering findings on treating apathy by the ADMET group. (yahoo.com)
  • The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. (nih.gov)
  • After adjusting for baseline, the methylphenidate group had significantly greater improvement in apathy than the placebo group at 4 weeks, 8 weeks, and 12 weeks. (nih.gov)
  • Although the word apathy was first used in 1594 and is derived from the Greek ἀπάθεια (apatheia), from ἀπάθης (apathēs, "without feeling" from a- ("without, not") and pathos ("emotion")), it is important not to confuse the two terms. (wikipedia.org)
  • The English word apathy originates from the Greek word apathes, which means "without pathos or feeling," 1 but scholars have shared various definitions. (psychiatrictimes.com)
  • It provides three rating scales to help diagnose apathy in Parkinson's, medication and counseling options to treat apathy, education and lifestyle changes to relieve apathy symptoms. (stanford.edu)
  • Medication options to treat apathy are, unfortunately, limited. (michaeljfox.org)
  • In fact, we believe that apathy may be a very early sign of dementia and it can be evaluated with a brief questionnaire. (consumeraffairs.com)
  • Apathy can be misinterpreted as laziness, poor initiative or depression. (michaeljfox.org)
  • Our data suggest that diet-induced obesity is a cause, rather than an effect, of laziness [apathy]. (veteranstoday.com)
  • Dr. Marc Dalton of Dalton Psychiatry in Washington says he sees apathy in a number of his elderly patients. (cnn.com)
  • Research published in the Journal of Neurology, Neurosurgery and Psychiatry suggest that apathy can be caused by changes in the brain resulting from the condition, Parkinson's UK reports. (barchester.com)
  • If so, your apathy may be down to specific brain differences, according to a team of researchers from Oxford University in the UK. (medicalnewstoday.com)
  • He and his team decided to study healthy people to determine whether there were any brain differences that could underpin apathy. (medicalnewstoday.com)
  • Apathy may be one of the most common behavioural symptoms of neurodegenerative and other brain disorders yet it is one of the most underrecognised, underdiagnosed, and poorly managed aspects of these diseases. (hindawi.com)
  • Apathy has also been shown to correlate with a poorer adherence to medication regimens and/or response to treatment (as after deep brain stimulation surgery, for example). (michaeljfox.org)
  • A study published Wednesday in the journal Neurology, and funded by the National Institutes of Health's National Institute of Aging, found that older folks, who are apathetic - but not depressed - may be suffering from smaller brain volumes than those without apathy. (cnn.com)
  • All underwent brain MRI scans and were later asked questions that measured their apathy symptoms, such as lack of interest in things, giving up activities they once enjoyed and a lack of energy. (cnn.com)
  • Just as signs of memory loss may signal brain changes related to brain disease, apathy may indicate underlying changes,' says study author Lenore J. Launer with the National Institute on Aging and a member of the American Academy of Neurology. (cnn.com)
  • And the fact that participants in our study had apathy without depression should turn our attention to how apathy alone could indicate brain disease. (cnn.com)
  • Distinct structural brain circuits indicate mood and apathy profiles in bipolar disorder. (uio.no)
  • In summary, a pICA decomposition suggested BD patients showed distinct mood and apathy profiles differing from the original PANSS subscales, relating to distinct brain structural networks. (uio.no)
  • Understanding the mechanisms underlying apathy is therefore of urgent concern but this has proven difficult because widespread brain changes in neurodegenerative diseases make interpretation difficult and there is no good animal model. (pubmedcentralcanada.ca)
  • Voxel-based morphometry (VBM) was used to explore the correlations between whole-brain GM and i) Apathy, and ii) Affective Flattening, respectively. (ovid.com)
  • Although many patients with pathological apathy also suffer from depression, several studies have shown that the two syndromes are dissociable: apathy can occur independently of depression and vice versa. (wikipedia.org)
  • The findings also shed light on how patients with "pathological conditions of extreme apathy" may be helped. (medicalnewstoday.com)
  • In this review we develop a conceptual framework for understanding pathological apathy based on this current understanding of normal motivated behaviour. (bmj.com)
  • Apathy is mediated by frontocortical structures but this is specific to the left hemisphere at least for patients in the mild to moderate stages of AD. (nih.gov)
  • Discuss how nurses can recognize and intervene with patients suffering fatigue and apathy. (asaging.org)
  • However, the effect of apathy subtypes and how they translate into functioning in everyday life and wellbeing in MND, for both the patients and their families, are seldom explored. (uea.ac.uk)
  • Apathy reduces the quality of life for patients with dementia and increases the workload for caregivers. (alzinfo.org)
  • M. Jonsson, A. Edman, K. Lind, et al: "Apathy is a Prominent Neuropsychiatric Feature of Radiological White-matter Changes in Patients with Dementia. (alzinfo.org)
  • Differentiating apathy and depression, understanding their unique effects, and appropriately identifying apathy symptoms in patients have robust implications for the development of neuropsychological models of these effects in PD as well as practical implications in guiding improvements to patient care and enhancing quality of life in patients and caregivers. (unboundmedicine.com)
  • There are several valid and reliable scales to measure the severity of apathy in patients with psychiatric and neurological disorders. (bmj.com)
  • When it comes to apathy, researchers at McGill University in Montreal claimed that half of the stroke patients experience apathy and even a minor apathy may prove to be a hindrance to recovery. (healthjockey.com)
  • Nancy E. Mayo, Ph.D., lead author of the study and the James McGill Professor in the Department of Medicine mentioned "Apathy is generally understudied in stroke patients, but we found that even relatively low levels can seriously impede recovery. (healthjockey.com)
  • In this context, we have developed "ECOCAPTURE", a method aimed at providing quantifiable and objective signature(s) of apathy in order to assess it and identify its precise underlying mechanisms. (frontiersin.org)
  • Teachers start the school year with high hopes, but many-especially those in low-income, predominantly minority schools-soon become disillusioned and discouraged in the face of widespread student apathy. (ascd.org)
  • The bad news is that apathy towards poaching in marine protected areas is widespread," said co-author Dr Michele Barnes, "but the good news is that there are already many tools and programs to encourage citizens to report poaching and other types of crimes. (eurekalert.org)
  • Apathy is widespread in mild forms in many people. (pubmedcentralcanada.ca)
  • Despite this, for a multitude of reasons, vaccination apathy is a widespread global issue and a key barrier to protecting the community against infectious disease. (presseportal.de)
  • These findings reveal that effort sensitivity and translations of intentions into actions might make a critical contribution to behavioral apathy," the researchers conclude. (medicalnewstoday.com)
  • After nine years, the researchers evaluated the participants' medical records to determine how apathy played a role in the development of dementia. (consumeraffairs.com)
  • The participants were divided into one of three groups based on their levels of apathy, and the researchers learned that those who were the most apathetic at the start of the study had a significantly higher risk of developing dementia. (consumeraffairs.com)
  • Overall, the researchers determined that severe apathy in older age was associated with an 80 percent increased risk of developing dementia. (consumeraffairs.com)
  • Depression is often thought to be a risk factor for dementia but this may be because some depression scales used by clinicians and researchers partially assess apathy, say scientists from the universities of Cambridge, King's College London, Radboud and Oxford. (neurosciencenews.com)
  • Behavioural syndromes such as apathy may inform diagnostic aspects of different types of dementia. (hindawi.com)
  • Rather than the preferred human lifestyle, apathy is now considered a defective behavioural state. (bmj.com)
  • Apathy is a complex, behavioural disorder associated with reduced spontaneous initiation of actions. (pubmedcentralcanada.ca)
  • At the recent 2017 World Health Summit - one of the world's most prestigious strategic forums on global health - a group of prominent global experts participated in a panel discussion on vaccination apathy, assessing the extent of influence it has on vaccination uptake, its causes, the role of healthcare providers, and how behavioural economics can help understand and address it. (presseportal.de)
  • If these findings are confirmed, identifying people with apathy earlier may be one way to target an at-risk group,' notes Launer. (cnn.com)
  • Notably, the regions associated with apathy scores were distinct from those associated with Affective Flattening, and these findings remained after controlling for antipsychotic medication dosage. (ovid.com)
  • The present findings set the stage for future larger-scale studies confirming the structural and neurochemical substrates of apathy in schizophrenia. (ovid.com)
  • This exploration deficit was correlated with apathy, disinhibition and cognitive and behavioral dysexecutive syndromes. (frontiersin.org)
  • Apathy is seen in approximately 1.4% to 15.8% of individuals who have no cognitive deficits. (psychiatrictimes.com)
  • 1,6,7,9-11 The prevalence rates for apathy among individuals with mild cognitive impairment ranges from 3.1% to 50.5% . (psychiatrictimes.com)
  • 9 Risk factors for developing apathy include older age and greater severity of cognitive impairment. (psychiatrictimes.com)
  • Individuals with dementia who present with apathy often have more rapid cognitive decline and are more impaired in their activities of daily living. (psychiatrictimes.com)
  • Apathy is not only associated with cognitive impairment, but also with impaired daily functioning, caregiver burden and distress, medication noncompliance, and increased mortality. (unboundmedicine.com)
  • Safety will also be measured by examining neuropsychiatric symptoms other than apathy using the Neuropsychiatric Inventory (NPI). (clinicaltrials.gov)
  • Additionally, the degree of apathy correlated with the level of functional impairment and dementia severity across all 3 types of dementia. (psychiatrictimes.com)
  • Changes from baseline to 6 months in other neuropsychological assessments as measured using the Dementia Apathy Interview and Rating (DAIR) scale will also be assessed. (clinicaltrials.gov)
  • Apathy is something that all people face in some capacity and is a natural response to disappointment, dejection, and stress. (wikipedia.org)
  • With the addition of the handheld device and the screen between people, apathy has also become a common occurrence on the net as users observe others being bullied, slandered, threatened or sent disturbing images. (wikipedia.org)
  • Palma de Jorge says now the apathy of many young people is due largely to Brazil's political and economic stability -- which means youth aren't forced to consider their rights or how they got them. (npr.org)
  • What we are seeing not just is Washington, D.C. but across the nation is the results of fifty plus years of apathy of the American people. (newswithviews.com)
  • Here, item response theory [ 2 ] was used as a basis to explore a possible early screening tool for apathy in elderly people. (hindawi.com)
  • Apathy can be very distressing for family members, when people no longer want to get together with family or friends or don't seem interested in what they used to enjoy," said researcher Dr. Meredith Bock. (consumeraffairs.com)
  • Kolkata, July 27 (PTI) A heart-wrenching video of a woman crying and pleading for help from bystanders to help her sexagenarian husband, a suspected COVID-19 patient, into an ambulance at Bongaon in West Bengal went viral and the apathy of the people seen around them has come in for flak. (yahoo.com)
  • The research shows how it may be possible to make a pill to restore vigor in people suffering from chronic fatigue and apathy brought on by cancer, congestive heart failure, kidney disease, and many other conditions - without the side-effects of stimulants such as caffeine or amphetamines. (oregonlive.com)
  • Older age and more severe motor symptoms also seem to put people at higher risk of developing apathy. (michaeljfox.org)
  • People with apathy usually don t realize there is a problem. (michaeljfox.org)
  • Stop bitching about it, you have a problem with apathy, don t use lame tactics to make people choose your side agains him/her. (offspring.com)
  • Mowa hopes his designs will act as a trigger against political apathy among young people. (designindaba.com)
  • How do the levels of different types of apathy change over time in people living with MND? (uea.ac.uk)
  • What impact do apathy subtypes have on wellbeing, quality of life and caregiver burden in people with MND and their families? (uea.ac.uk)
  • Scientists at the University Medical Center Utrecht in the Netherlands found that people with two or more of these symptoms had 1.4% smaller gray matter and 1.6% less white matter in their brains than those who showed little or no apathy. (cnn.com)
  • Apathy symptoms are common in older people without dementia. (cnn.com)
  • But the data does seem to show, they say, that apathy in older people could signal something more than just moodiness. (cnn.com)
  • So many people who are struggling with apathy are constantly complaining about their situation and just how bad things are. (addicted2success.com)
  • It is only natural for people to want to know why something so chaotic is happening to them, but others have a tendency to display another response: apathy. (myduhawk.com)
  • The results of one study showed that individuals with frontotemporal dementia (FTD) and vascular dementia (VaD) report more severe apathy than individuals with Alzheimer disease (AD). (psychiatrictimes.com)
  • It is responsible for the most severe form of apathy and in most cases the lesions affect bilaterally the associative and limbic territories of the internal portion of the globus pallidus. (nih.gov)
  • Abulia is considered a more severe type of apathy, but its nosological position is still unclear. (bmj.com)
  • Defined as a state of impassivity associated with a lack of interest, concern or enthusiasm, apathy is dissociable from depression ( Marin, 1991 ). (pubmedcentralcanada.ca)
  • Apathy can be overcome by enthusiasm, and enthusiasm can only be aroused by two things: first, an ideal, with takes the imagination by storm, and second, a definite intelligible plan for carrying that ideal into practice. (addicted2success.com)
  • Apathy is a complete lack of feeling or concern for something or someone. (writersdigest.com)
  • Second, an apathy epidemic: as the killings escalate, public concern about them has waned. (wordpress.com)

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