The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.
Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.
The protrusion of an organ or part of an organ into a natural or artificial orifice.
The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.
BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
Downward displacement of the UTERUS. It is classified in various degrees: in the first degree the UTERINE CERVIX is within the vaginal orifice; in the second degree the cervix is outside the orifice; in the third degree the entire uterus is outside the orifice.
Protrusion of the rectal mucous membrane through the anus. There are various degrees: incomplete with no displacement of the anal sphincter muscle; complete with displacement of the anal sphincter muscle; complete with no displacement of the anal sphincter muscle but with herniation of the bowel; and internal complete with rectosigmoid or upper rectum intussusception into the lower rectum.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
Abnormal protrusion of one or more of the leaflets of TRICUSPID VALVE into the RIGHT ATRIUM during SYSTOLE. This allows the backflow of blood into right atrium leading to TRICUSPID VALVE INSUFFICIENCY; SYSTOLIC MURMURS. Its most common cause is not primary valve abnormality but rather the dilation of the RIGHT VENTRICLE and the tricuspid annulus.
Abnormal descent of a pelvic organ resulting in the protrusion of the organ beyond its normal anatomical confines. Symptoms often include vaginal discomfort, DYSPAREUNIA; URINARY STRESS INCONTINENCE; and FECAL INCONTINENCE.
The valve between the left atrium and left ventricle of the heart.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Downward displacement of any one of the HEART VALVES from its normal position. This usually results in failed valve closure.
Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
Graphic registration of the heart sounds picked up as vibrations and transformed by a piezoelectric crystal microphone into a varying electrical output according to the stresses imposed by the sound waves. The electrical output is amplified by a stethograph amplifier and recorded by a device incorporated into the electrocardiograph or by a multichannel recording machine.
Surgical insertion of synthetic material to repair injured or diseased heart valves.
Act of listening for sounds within the heart.
Heart sounds caused by vibrations resulting from the flow of blood through the heart. Heart murmurs can be examined by HEART AUSCULTATION, and analyzed by their intensity (6 grades), duration, timing (systolic, diastolic, or continuous), location, transmission, and quality (musical, vibratory, blowing, etc).
A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.
Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers.
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
A valve situated at the entrance to the pulmonary trunk from the right ventricle.
The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.
Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
A HERNIA-like condition in which the weakened pelvic muscles cause the URINARY BLADDER to drop from its normal position. Fallen urinary bladder is more common in females with the bladder dropping into the VAGINA and less common in males with the bladder dropping into the SCROTUM.
The tendinous cords that connect each cusp of the two atrioventricular HEART VALVES to appropriate PAPILLARY MUSCLES in the HEART VENTRICLES, preventing the valves from reversing themselves when the ventricles contract.
A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
The prolapse or downward displacement of the VISCERA.
Herniation of the RECTUM into the VAGINA.
Pathologic deposition of calcium salts in tissues.
Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Surgery performed on the female genitalia.
Soft tissue formed mainly by the pelvic diaphragm, which is composed of the two levator ani and two coccygeus muscles. The pelvic diaphragm lies just below the pelvic aperture (outlet) and separates the pelvic cavity from the PERINEUM. It extends between the PUBIC BONE anteriorly and the COCCYX posteriorly.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.
The plan and delineation of prostheses in general or a specific prosthesis.
Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.
Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
Small circumscribed melanoses resembling, but differing histologically from, freckles. The concept includes senile lentigo ('liver spots') and nevoid lentigo (nevus spilus, lentigo simplex) and may also occur in association with multiple congenital defects or congenital syndromes (e.g., Peutz-Jeghers syndrome).
Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Flaps within the VEINS that allow the blood to flow only in one direction. They are usually in the medium size veins that carry blood to the heart against gravity.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annuli of HEART VALVES. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.
Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.
The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.

Transesophageal echocardiographic description of the mechanisms of aortic regurgitation in acute type A aortic dissection: implications for aortic valve repair. (1/12)

OBJECTIVES: The purpose of this study was to use transesophageal echocardiography (TEE) to define the mechanisms of aortic regurgitation (AR) in acute type A aortic dissection so as to assist the surgeon in identifying patients with mechanisms of AR suitable for valve preservation. BACKGROUND: Significant AR frequently complicates acute type A aortic dissection necessitating either aortic valve repair or replacement at the time of aortic surgery. Although direct surgical inspection can identify intrinsically normal leaflets suitable for repair, it is preferable for the surgeon to correlate aortic valve function with the anatomy prior to thoracotomy. METHODS: We studied 50 consecutive patients with acute type A aortic dissection in whom preoperative TEE findings were considered by the surgeons in planning aortic valve surgery. Six patients did not undergo surgery (noncandidacy or refusal) and one patient had had a prior aortic valve replacement and therefore was excluded from the analysis. RESULTS: Twenty-seven patients had no or minimal AR and 22 had moderate or severe AR. In all, there were 16 with intrinsically normal leaflets who had AR due to one or more correctable aortic valve lesion: incomplete leaflet closure due to leaflet tethering in a dilated aortic root in 7; leaflet prolapse due to disrupted leaflet attachments in 8; and dissection flap prolapse through the aortic valve orifice in 5. Of these 16 patients, 15 had successful aortic valve repair whereas just 1 underwent aortic valve replacement after a complicated intraoperative course (unrelated to the aortic valve). Nine patients underwent aortic valve replacement for nonrepairable abnormalities, including Marfan's syndrome in four, bicuspid aortic valve in four, and aortitis in one. In patients undergoing aortic valve repair, follow-up transthoracic echocardiography at a median of three months revealed no or minimal residual AR, and clinical follow-up at a median of 23 months showed that none required aortic valve replacement. CONCLUSIONS: When significant AR complicates acute type A aortic dissection, TEE can define the severity and mechanisms of AR and can assist the surgeon in identifying patients in whom valve repair is likely to be successful.  (+info)

Imbalance of cusp width and aortic regurgitation associated with aortic cusp prolapse in ventricular septal defect. (2/12)

The Doppler echocardiograms of the aortic valve and associated aortic regurgitation (AR) were reviewed in 72 patients with a ventricular septal defect (VSD). Group I comprised 13 patients without any deformity of the aortic cusp for > or = 10 years, group 2 included 35 patients who did not develop AR for > or = 10 years after right coronary cusp prolapse (RCCP) was first detected, group 3 comprised 11 patients with RCCP and AR in whom the AR remained subclinical for > or = 10 years, and group 4 was 13 patients who underwent surgical treatment because of moderate to severe AR. The cusp imbalance index [width of right (R) or non- (N) coronary cusp/width of left coronary cusp (L)] was compared among the 4 groups. R/L or N/L was larger in group 4 than in groups 1-3; R/L exceeded 1.30 in all the patients in group 4, whereas it was less than 1.30 in all the atients in groups 1-3. Two patients in group 4 with non-coronary cusp prolapse had an N/L greater than 1.50. No other patients in any group had an N/L larger than 1.20. An imbalance of cusp width may predict possible progressive deterioration of AR.  (+info)

Clinical significance of iodine-123-15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid myocardial scintigraphy in patients with aortic valve disease. (3/12)

The present study sought to determine whether myocardial fatty acid metabolism as assessed with iodine-123-labeled 15-(p-iodophenyl)-3-R,S-methylpentadecanoic acid (BMIPP) scintigraphy is impaired in patients with aortic valve disease (AVD) and whether the degree of the metabolic abnormality reflects the severity of AVD. BMIPP scintigraphy was performed in 12 patients with aortic stenosis (AS), 14 patients with aortic regurgitation (AR), and 9 healthy volunteers, and from that the heart-mediastinum uptake ratio (H/M ratio) corrected by the left ventricular (LV) mass (U/Mass ratio) and the myocardial washout rate (WR) were obtained. The H/M ratio tended to be higher in patients than in healthy volunteers (3.3 +/- 0.7 for AS, 3.5 +/- 0.5 for AR, 3.0 +/- 0.3 for healthy volunteers), and the WR was significantly higher in patients than in healthy volunteers (42.8 +/- 9.1% for AS, 35.7 +/- 6.5% for AR, 19.6 +/- 9.1% for healthy volunteers, p<0.01). In the AS patients, the U/Mass ratio showed significant negative correlations (r=-0.79 to -0.90, all p<0.01) and the WR showed significant positive correlations (r=0.61 to 0.82, all p<0.01) with transaortic pressure gradient, LV wall thickness, and LV mass. Similarly, in AR patients these BMIPP parameters showed proportional changes to the LV volumes and LV mass (r=-0.79 to -0.83, all p<0.01 for U/Mass ratio, r=0.55 to 0.70, p<0.05 to <0.01 for WR). In the 9 patients who underwent aortic valve replacement, the BMIPP parameters tended to normalize with increasing U/Mass ratio (0.90 +/- 0.41 x 10(-2)/g to 1.34 +/- 0.59 x 10(-2)/g, p<0.05) and decreasing WR (41.9 +/- 8.8% to 35.4 +/- 9.2%, p<0.01) after surgery. Myocardial fatty acid metabolism as assessed with BMIPP scintigraphy was impaired in patients with aortic valve disease and the U/Mass ratio and WR reflect the severity. These parameters may be useful for the noninvasive assessment of the myocardial metabolic abnormalities caused by hemodynamic overload.  (+info)

Eccentric aortic regurgitation in patients with right coronary cusp prolapse complicating a ventricular septal defect. (4/12)

To analyze the clinical significance of eccentric aortic regurgitation (AR) complicating the right coronary cusp prolapse associated with a ventricular septal defect (VSD), the Doppler echocardiograms of 129 patients were reviewed. In 102 patients, AR was classified as mild and in 27 patients it was classified as moderate. Eccentric AR was defined as the jet distributing in an eccentric direction. In 15 patients of the moderate group, AR was already moderate at the initial examination and of these, the AR was eccentric in 14 and central in 1. In 12 patients who initially had mild AR, it became moderate during follow-up. In 7 patients with mild, central AR, 6 worsened to central moderate AR and 1 evolved to eccentric moderate AR. Eccentric mild AR patients all developed eccentric moderate AR. Within the mild AR group, 5 of 9 patients with eccentric AR progressed from mild to moderate, whereas only 7 of 105 patients with central AR did so (p<0.01). In conclusion, eccentric AR may be an advanced finding of the AR associated with right coronary cusp prolapse in some patients, but in others eccentric AR is highly likely to progress and is malignant.  (+info)

Severity indices of right coronary cusp prolapse and aortic regurgitation complicating ventricular septal defect in the outlet septum: which defect should be closed? (5/12)

BACKGROUND: The factors that may determine the evolution of right coronary cusp prolapse (RCCP) and regurgitation (AR) associated with a ventricular septal defect in the outlet septum (outlet VSD) have not been clarified. METHODS AND RESULTS: The Doppler echocardiograms of 316 patients were grouped according to both the development of RCCP, and the values of the right coronary cusp deformity index (RCCD) and the right coronary cusp imbalance index (R/L). All detected AR was /=0.30 or R/L >/=0.30. Rupture of the sinus of Valsalva was identified in patients with RCCD >/=0.30. A significantly large number of patients with both RCCD >/=0.30 and R/L >/=1.30 (p<0.01), and a few patients with either RCCD >/=0.30 or R/L >/=0.30 underwent aortic valvuloplasty or replacement. Operative outcome for AR /=0.30 or R/L >/=1.30.  (+info)

Repair of trileaflet aortic valve prolapse: mid-term outcome in patients with normal aortic root morphology. (6/12)

We described our mid-term results in repairing prolapsing aortic cusps in 21 patients with aortic regurgitation and normal aortic root morphology. Aortic regurgitation was moderate-severe in five patients and severe in 16 patients. Prolapse involved the left cusp in four patients (19%), the right cusp in 10 patients (47%) and the non-coronary cusp in 7 (33%) patients. Correction of the prolapsing cusp was achieved by either free edge plication, triangular resection or resuspension with polytetrafluoroethylene sutures, frequently associated to a subcommissural annuloplasty. There was no hospital death. At discharge transthoracic echocardiography, 18 patients (85%) showed no residual aortic regurgitation and three patients (14%) had trivial aortic regurgitation with a central jet. Mean clinical follow-up was 27.2+/-17.1 months (range: 10-72 months). Overall survival was 90.5%. At follow-up transthoracic echocardiography, fourteen patients (73%) were free from aortic regurgitation and five patients (26%) had mild aortic regurgitation without clinical signs of congestive heart failure. Correction of valve prolapse appears a reasonable extension of the original techniques of valve-preserving surgery.  (+info)

Valve-sparing aortic root replacement with repair of leaflet prolapse after Ross operation. (7/12)

The need for reoperation remains a principal limitation of the Ross procedure and most commonly includes replacement of the neo-aortic valve. Valve-preserving aortic root replacement has recently evolved into an increasingly accepted treatment modality for patients with neo-aortic valve regurgitation. Leaflet prolapse, however, may be present, making composite replacement the most frequent choice. Alternatively, valve preservation may be combined with correction of leaflet prolapse. We describe the use of a valve-sparing procedure with correction of leaflet prolapse in a patient with progressive dilatation of the pulmonary autograft and severe regurgitation of the neo-aortic valve.  (+info)

Acute aortic valve prolapse in Marfan's syndrome. (8/12)

A 22 year old man with Marfan's syndrome died suddenly following acute aortic valve prolapse. Although aortic root involvement in Marfan's syndrome is common, we have found no previous description of this particular complication in the literature.  (+info)

The condition is often diagnosed using echocardiography, and treatment options include medication to regulate the heart rhythm and reduce blood pressure, or in severe cases, surgical replacement of the aortic valve may be necessary.

There are several types of MVP, including:

1. Primary MVP: This is the most common type of MVP and occurs when the mitral valve leaflets are too long and prolapse into the left atrium.
2. Secondary MVP: This type of MVP occurs when another condition, such as a heart murmur or an enlarged heart, causes the mitral valve to prolapse.
3. Functional MVP: This type of MVP is caused by abnormal functioning of the mitral valve rather than any physical defect.
4. Rheumatic MVP: This type of MVP is caused by inflammation of the mitral valve due to rheumatic fever.

The symptoms of MVP can vary in severity and may include:

* Chest pain or discomfort
* Shortness of breath
* Palpitations or fluttering in the chest
* Fatigue
* Dizziness or lightheadedness
* Coughing up pink, foamy fluid (in severe cases)

If you experience any of these symptoms, it is important to see a doctor for proper diagnosis and treatment. MVP can be diagnosed with an echocardiogram, which uses sound waves to create images of the heart. Treatment options for MVP include medications to control symptoms, lifestyle changes such as regular exercise and a healthy diet, and in severe cases, surgery to repair or replace the mitral valve.

In conclusion, mitral valve prolapse is a relatively common condition that can cause a range of symptoms. It is important to seek medical attention if you experience any of these symptoms so that proper diagnosis and treatment can be provided. With appropriate treatment, most people with MVP can lead normal, active lives.

There are several types of prolapse, including:

1. Pelvic organ prolapse: This occurs when the muscles and tissues in the pelvis weaken, causing an organ to slip out of place. It can affect the uterus, bladder, or rectum.
2. Hemorrhoidal prolapse: This occurs when the veins in the rectum become swollen and protrude outside the anus.
3. Small intestine prolapse: This occurs when a portion of the small intestine slides into another part of the digestive tract.
4. Uterine prolapse: This occurs when the uterus slips out of place, often due to childbirth or menopause.
5. Cervical prolapse: This occurs when the cervix slips down into the vagina.

Symptoms of prolapse can include:

* A bulge or lump in the vaginal area
* Pain or discomfort in the pelvic area
* Difficulty controlling bowel movements or urine leakage
* Difficulty having sex due to pain or discomfort
* Feeling of fullness or heaviness in the pelvic area

Treatment for prolapse depends on the type and severity of the condition, and can include:

1. Kegel exercises: These exercises can help strengthen the muscles in the pelvic floor.
2. Pelvic floor physical therapy: This can help improve bladder and bowel control, as well as reduce pain.
3. Medications: These can include hormones to support bone density, as well as pain relievers and anti-inflammatory drugs.
4. Surgery: In some cases, surgery may be necessary to repair or replace damaged tissue.
5. Lifestyle changes: Making healthy lifestyle changes such as losing weight, quitting smoking, and avoiding heavy lifting can help manage symptoms of prolapse.

It's important to seek medical attention if you experience any symptoms of prolapse, as early treatment can help improve outcomes and reduce the risk of complications.

There are several types of heart valve diseases, including:

1. Mitral regurgitation: This occurs when the mitral valve does not close properly, allowing blood to flow backward into the left atrium.
2. Aortic stenosis: This occurs when the aortic valve becomes narrowed or blocked, restricting blood flow from the left ventricle into the aorta.
3. Pulmonary stenosis: This occurs when the pulmonary valve becomes narrowed or blocked, restricting blood flow from the right ventricle into the pulmonary artery.
4. Tricuspid regurgitation: This occurs when the tricuspid valve does not close properly, allowing blood to flow backward into the right atrium.
5. Heart valve thickening or calcification: This can occur due to aging, rheumatic fever, or other conditions that cause inflammation in the heart.
6. Endocarditis: This is an infection of the inner lining of the heart, which can damage the heart valves.
7. Rheumatic heart disease: This is a condition caused by rheumatic fever, which can damage the heart valves and cause scarring.
8. Congenital heart defects: These are heart defects that are present at birth, and can affect the heart valves as well as other structures of the heart.

Symptoms of heart valve disease can include shortness of breath, fatigue, swelling in the legs or feet, and chest pain. Treatment options for heart valve disease depend on the specific condition and can range from medication to surgery or other procedures.

Treatment options for uterine prolapse include lifestyle changes such as exercise, weight loss, and pelvic floor exercises, as well as surgical procedures such as hysterectomy or vaginal repair. The choice of treatment depends on the severity of the condition and the individual's overall health status.

It is important to seek medical advice if symptoms persist or worsen over time, as uterine prolapse can lead to complications such as urinary incontinence, kidney damage, and bowel problems if left untreated. Early diagnosis and treatment can help prevent these complications and improve quality of life for individuals affected by the condition.

Symptoms of rectal prolapse may include:

* A bulge or lump near the anus
* Pain or discomfort in the rectal area
* Difficulty controlling bowel movements
* Leaking of stool or gas
* Difficulty sitting or passing stool

If left untreated, rectal prolapse can lead to complications such as:

* Increased risk of anal fissures and skin irritation
* Infection of the rectal area
* Impaired urinary continence
* Increased risk of recurrent prolapse

Treatment options for rectal prolapse depend on the severity of the condition and may include:

* Dietary changes and bowel training to improve bowel habits
* Exercise and physical therapy to strengthen the pelvic floor muscles
* Use of rectal inserts or devices to support the rectum
* Surgery to repair or remove the prolapsed rectum

It is important to seek medical attention if symptoms of rectal prolapse are present, as early treatment can help prevent complications and improve quality of life.

There are several causes of aortic valve insufficiency, including:

1. Congenital heart defects
2. Rheumatic fever
3. Endocarditis (infection of the inner lining of the heart)
4. Aging and wear and tear on the valve
5. Trauma to the chest
6. Connective tissue disorders such as Marfan syndrome or Ehlers-Danlos syndrome.

Symptoms of aortic valve insufficiency can include fatigue, shortness of breath, swelling in the legs and feet, and chest pain. Diagnosis is typically made through a combination of physical examination, echocardiogram (ultrasound of the heart), electrocardiogram (ECG or EKG), and chest X-ray.

Treatment options for aortic valve insufficiency depend on the severity of the condition and may include:

1. Medications to manage symptoms such as heart failure, high blood pressure, and arrhythmias (abnormal heart rhythms)
2. Lifestyle modifications such as a healthy diet and regular exercise
3. Repair or replacement of the aortic valve through surgery. This may involve replacing the valve with an artificial one, or repairing the existing valve through a procedure called valvuloplasty.
4. In some cases, catheter-based procedures such as balloon valvuloplasty or valve replacement may be used.

It is important to note that aortic valve insufficiency can lead to complications such as heart failure, arrhythmias, and endocarditis, which can be life-threatening if left untreated. Therefore, it is important to seek medical attention if symptoms persist or worsen over time.

The term "prolapse" refers to the abnormal descent of an organ or structure from its normal position. In this case, the tricuspid valve is unable to close completely due to a defect in the valve tissue or supporting structures, leading to regurgitation (leakage) of blood through the valve.

Tricuspid valve prolapse can be caused by a variety of factors, including congenital heart defects, connective tissue disorders, and age-related wear and tear on the valve. Diagnosis typically involves echocardiography or other imaging tests to assess the function and structure of the tricuspid valve. Treatment options may include medication to manage symptoms, lifestyle modifications, or surgical intervention in severe cases.

There are several types of POP, including:

1. Cystocele (bladder prolapse): The bladder bulges into the vagina.
2. Rectocele (rectum prolapse): The rectum bulges into the vagina.
3. Uterine prolapse (womb prolapse): The uterus drops from its normal position and moves into the vagina.
4. Small intestine prolapse: A part of the small intestine bulges into the vagina.

Pelvic organ prolapse is caused by weakened muscles and tissues in the pelvis, which can be due to a variety of factors such as childbirth, menopause, obesity, chronic straining during bowel movements, and certain medical conditions like multiple sclerosis or spinal cord injuries.

Treatment options for POP include:

1. Kegel exercises to strengthen the pelvic muscles.
2. Lifestyle changes such as losing weight, quitting smoking, and avoiding heavy lifting.
3. Physical therapy to improve pelvic floor muscle function and strength.
4. Surgery to repair or remove damaged tissues and support the pelvic organs.
5. Pelvic mesh implantation to provide additional support to the weakened tissues.

It's important to seek medical attention if you experience any symptoms of POP, as it can have a significant impact on your quality of life and may lead to complications such as urinary tract infections or rectal bleeding if left untreated.

There are several types of heart valve prolapse, including:

1. Mitral valve prolapse (MVP): This is the most common type of heart valve prolapse and occurs when the mitral valve bulges into the left atrium.
2. Tricuspid valve prolapse (TVP): This occurs when the tricuspid valve bulges into the right atrium.
3. Pulmonary valve prolapse (PVP): This occurs when the pulmonary valve bulges into the right ventricle.
4. Aortic valve prolapse (AVP): This is a rare condition that occurs when the aortic valve bulges into the left ventricle.

Heart valve prolapse can be caused by a variety of factors, including:

1. Genetics: Many people with heart valve prolapse have a family history of the condition.
2. Heart defects present at birth: Some people may be born with heart defects that increase their risk of developing heart valve prolapse.
3. Heart disease: Conditions such as hypertension, coronary artery disease, and heart failure can damage the heart valves and lead to prolapse.
4. Age-related wear and tear: As people age, their heart valves can become worn out and less effective, leading to prolapse.
5. Infections: Endocarditis, an infection of the inner lining of the heart, can damage the heart valves and lead to prolapse.

Treatment for heart valve prolapse depends on the severity of the condition and may include:

1. Medications: Drugs such as beta blockers, diuretics, and anticoagulants may be prescribed to manage symptoms such as high blood pressure, fluid buildup, and blood clots.
2. Lifestyle changes: Patients with heart valve prolapse may need to make lifestyle changes such as eating a healthy diet, getting regular exercise, and avoiding strenuous activities.
3. Surgery: In severe cases of heart valve prolapse, surgery may be necessary to repair or replace the damaged valve.
4. Transcatheter procedures: Minimally invasive procedures such as balloon valvuloplasty or valve replacement can be performed through a catheter inserted into a blood vessel in the leg.

It is important for individuals with heart valve prolapse to follow their doctor's recommendations and attend regular check-ups to monitor their condition and prevent complications. With proper treatment, many people with heart valve prolapse can lead active and fulfilling lives.

The mitral valve is located between the left atrium and the left ventricle, and it is responsible for regulating blood flow between these two chambers. When the mitral valve does not close properly, blood can leak back into the left atrium, causing a range of symptoms and complications.

There are several causes of mitral valve insufficiency, including:

* Degenerative changes: The mitral valve can wear out over time due to degenerative changes, such as calcium buildup or tearing of the valve flaps.
* Heart muscle disease: Diseases such as cardiomyopathy can cause the heart muscle to weaken and stretch, leading to mitral valve insufficiency.
* Endocarditis: Infections of the inner lining of the heart can damage the mitral valve and lead to insufficiency.
* Heart defects: Congenital heart defects, such as a bicuspid valve or a narrow valve opening, can lead to mitral valve insufficiency.

Treatment for mitral valve insufficiency depends on the severity of the condition and may include medications to manage symptoms, lifestyle changes, or surgery to repair or replace the damaged valve. In some cases, catheter-based procedures may be used to repair the valve without open-heart surgery.

Overall, mitral valve insufficiency is a common condition that can have a significant impact on quality of life if left untreated. It is important to seek medical attention if symptoms persist or worsen over time.

There are two main types of heart murmurs:

1. Innocent murmurs: These are benign murmurs that are not caused by any underlying heart condition. They are often heard in healthy children and may disappear as the child grows.
2. Abnormal murmurs: These are murmurs that are caused by an underlying heart condition, such as a congenital heart defect or heart valve disease. These murmurs can be a sign of a serious heart problem and may require further evaluation and treatment.

Heart murmurs can be diagnosed by a pediatrician or cardiologist using a stethoscope to listen to the heart sounds. Additional tests, such as an echocardiogram or electrocardiogram (ECG), may be ordered to confirm the diagnosis and determine the cause of the murmur.

Treatment for heart murmurs depends on the underlying cause of the condition. In some cases, no treatment may be needed, while in other cases, medication or surgery may be required. It is important for individuals with heart murmurs to receive regular follow-up care from a pediatrician or cardiologist to monitor the condition and address any complications that may arise.

In summary, heart murmurs are abnormal sounds heard during a heartbeat that can be a sign of an underlying heart condition. They can be diagnosed by a pediatrician or cardiologist using a stethoscope and additional tests, and treatment depends on the underlying cause of the condition. Regular follow-up care is important to monitor the condition and address any complications that may arise.

The symptoms of Marfan syndrome can vary widely among individuals with the condition, but typically include:

1. Tall stature (often over 6 feet 5 inches)
2. Long limbs and fingers
3. Curvature of the spine (scoliosis)
4. Flexible joints
5. Eye problems, such as nearsightedness, glaucoma, and detached retinas
6. Heart problems, such as mitral valve prolapse and aortic dilatation
7. Blood vessel problems, such as aneurysms and dissections
8. Lung problems, such as pneumothorax (collapsed lung)
9. Other skeletal problems, such as pectus excavatum (a depression in the chest wall) and clubfoot

Marfan syndrome is usually diagnosed through a combination of clinical evaluation, family history, and genetic testing. Treatment for the condition typically involves managing its various symptoms and complications, such as with medication, surgery, or lifestyle modifications. Individuals with Marfan syndrome may also need to avoid activities that could exacerbate their condition, such as contact sports or heavy lifting.

While there is currently no cure for Marfan syndrome, early diagnosis and appropriate management can help individuals with the condition live long and relatively healthy lives. With proper care and attention, many people with Marfan syndrome are able to lead fulfilling lives and achieve their goals.

Causes and risk factors:

The most common cause of bacterial endocarditis is a bacterial infection that enters the bloodstream and travels to the heart. This can occur through various means, such as:

* Injecting drugs or engaging in other risky behaviors that allow bacteria to enter the body
* Having a weakened immune system due to illness or medication
* Having a previous history of endocarditis or other heart conditions
* Being over the age of 60, as older adults are at higher risk for developing endocarditis

Symptoms:

The symptoms of bacterial endocarditis can vary depending on the severity of the infection and the location of the infected area. Some common symptoms include:

* Fever
* Chills
* Joint pain or swelling
* Fatigue
* Shortness of breath
* Heart murmurs or abnormal heart sounds

Diagnosis:

Bacterial endocarditis is diagnosed through a combination of physical examination, medical history, and diagnostic tests such as:

* Blood cultures to identify the presence of bacteria in the bloodstream
* Echocardiogram to visualize the heart and detect any abnormalities
* Chest X-ray to look for signs of infection or inflammation in the lungs or heart
* Electrocardiogram (ECG) to measure the electrical activity of the heart

Treatment:

The treatment of bacterial endocarditis typically involves a combination of antibiotics and surgery. Antibiotics are used to kill the bacteria and reduce inflammation, while surgery may be necessary to repair or replace damaged heart tissue. In some cases, the infected heart tissue may need to be removed.

Prevention:

Preventing bacterial endocarditis involves good oral hygiene, regular dental check-ups, and avoiding certain high-risk activities such as unprotected sex or sharing of needles. People with existing heart conditions should also take antibiotics before dental or medical procedures to reduce the risk of infection.

Prognosis:

The prognosis for bacterial endocarditis is generally good if treatment is prompt and effective. However, delays in diagnosis and treatment can lead to serious complications such as heart failure, stroke, or death. Patients with pre-existing heart conditions are at higher risk for complications.

Incidence:

Bacterial endocarditis is a relatively rare condition, affecting approximately 2-5 cases per million people per year in the United States. However, people with certain risk factors such as heart conditions or prosthetic heart valves are at higher risk for developing the infection.

Complications:

Bacterial endocarditis can lead to a number of complications, including:

* Heart failure
* Stroke or brain abscess
* Kidney damage or failure
* Pregnancy complications
* Nerve damage or peripheral neuropathy
* Skin or soft tissue infections
* Bone or joint infections
* Septicemia (blood poisoning)

Prevention:

Preventive measures for bacterial endocarditis include:

* Good oral hygiene and regular dental check-ups to reduce the risk of dental infections
* Avoiding high-risk activities such as unprotected sex or sharing of needles
* Antibiotics before dental or medical procedures for patients with existing heart conditions
* Proper sterilization and disinfection of medical equipment
* Use of antimicrobial prophylaxis (prevention) in high-risk patients.

Emerging Trends:

Newly emerging trends in the management of bacterial endocarditis include:

* The use of novel antibiotics and combination therapy to improve treatment outcomes
* The development of new diagnostic tests to help identify the cause of infection more quickly and accurately
* The increased use of preventive measures such as antibiotic prophylaxis in high-risk patients.

Future Directions:

Future directions for research on bacterial endocarditis may include:

* Investigating the use of novel diagnostic techniques, such as genomics and proteomics, to improve the accuracy of diagnosis
* Developing new antibiotics and combination therapies to improve treatment outcomes
* Exploring alternative preventive measures such as probiotics and immunotherapy.

In conclusion, bacterial endocarditis is a serious infection that can have severe consequences if left untreated. Early diagnosis and appropriate treatment are crucial to improving patient outcomes. Preventive measures such as good oral hygiene and antibiotic prophylaxis can help reduce the risk of developing this condition. Ongoing research is focused on improving diagnostic techniques, developing new treatments, and exploring alternative preventive measures.

Symptoms of cystocele may include:

* A bulge in the vagina that may be felt through the skin
* Pain or discomfort during sexual activity
* Difficulty starting a stream of urine
* Frequent urination
* Increased urgency to urinate
* Leaking of urine

Diagnosis of cystocele is typically made through a physical exam and may also involve imaging tests such as ultrasound or MRI. Treatment for cystocele depends on the severity of the condition and may include:

* Kegel exercises to strengthen the muscles that support the bladder
* A pessary, which is a device inserted into the vagina to support the bladder
* Surgery to repair or remove the damaged tissue

It's important for individuals experiencing symptoms of cystocele to consult with a healthcare provider for proper diagnosis and treatment.

There are several types of visceral prolapse, including:

1. Small intestine prolapse (also known as intussusception): This occurs when a portion of the small intestine slides into another section of the intestine, causing a telescoping effect.
2. Large intestine prolapse (also known as rectal prolapse): This occurs when the rectum slips out of its normal position and moves towards the anus.
3. Uterine prolapse: This occurs when the uterus slips out of its normal position and moves into the vagina.
4. Bladder prolapse (also known as cystocele): This occurs when the bladder drops down from its normal position and pushes against the vaginal wall.

Visceral prolapse can be caused by a variety of factors, including:

1. Weakened muscles in the abdominal wall or pelvic floor
2. Increased pressure on the organs due to pregnancy, obesity, or other conditions
3. Previous surgery or injury to the abdominal or pelvic area
4. Neurological conditions that affect the nerves that control the organs
5. Age-related wear and tear on the organs and connective tissues

Symptoms of visceral prolapse can include:

1. Pain or discomfort in the abdomen or pelvis
2. Difficulty with bowel movements or urination
3. A bulge or lump in the abdomen or vagina
4. Feeling of fullness or pressure in the pelvic area
5. Difficulty controlling the flow of urine or stool

Treatment for visceral prolapse depends on the severity of the condition and can include:

1. Lifestyle changes, such as diet and exercise modifications
2. Physical therapy to strengthen the muscles in the pelvic floor
3. Medications to relax the muscles or improve bowel function
4. Surgery to repair or remove the prolapsed organ
5. In some cases, a pessary (a device that is placed in the vagina to support the prolapsed organ) may be recommended.

It's important to note that visceral prolapse can be a chronic condition, and it may take time and multiple treatments to manage the symptoms effectively. If you suspect you have visceral prolapse, it's important to seek medical attention to receive an accurate diagnosis and appropriate treatment.

Note: This definition is a general overview of the condition and may not cover all aspects of rectocele, its causes, symptoms, diagnosis, treatment, and management. It is advisable to consult a healthcare professional for detailed information and personalized advice.

There are several different types of calcinosis, each with its own unique causes and symptoms. Some common forms of calcinosis include:

1. Dystrophic calcinosis: This type of calcinosis occurs in people with muscular dystrophy, a group of genetic disorders that affect muscle strength and function. Dystrophic calcinosis can cause calcium deposits to form in the muscles, leading to muscle weakness and wasting.
2. Metastatic calcinosis: This type of calcinosis occurs when cancer cells spread to other parts of the body and cause calcium deposits to form. Metastatic calcinosis can occur in people with a variety of different types of cancer, including breast, lung, and prostate cancer.
3. Idiopathic calcinosis: This type of calcinosis occurs for no apparent reason, and the exact cause is not known. Idiopathic calcinosis can affect people of all ages and can cause calcium deposits to form in a variety of different tissues.
4. Secondary calcinosis: This type of calcidosis occurs as a result of an underlying medical condition or injury. For example, secondary calcinosis can occur in people with kidney disease, hyperparathyroidism (a condition in which the parathyroid glands produce too much parathyroid hormone), or traumatic injuries.

Treatment for calcinosis depends on the underlying cause and the severity of the condition. In some cases, treatment may involve managing the underlying disease or condition that is causing the calcium deposits to form. Other treatments may include medications to reduce inflammation and pain, physical therapy to improve mobility and strength, and surgery to remove the calcium deposits.

Mitral valve stenosis can be caused by a variety of factors, including:

* Calcification of the mitral valve due to aging or rheumatic fever
* Scarring of the mitral valve due to heart disease or injury
* Birth defects that affect the development of the mitral valve
* Rheumatoid arthritis, which can cause inflammation and scarring of the mitral valve

Symptoms of mitral valve stenosis may include:

* Shortness of breath
* Fatigue
* Swelling in the legs, ankles, and feet
* Chest pain
* Dizziness or lightheadedness
* Palpitations

If you suspect you or someone else may have mitral valve stenosis, it is important to seek medical attention as soon as possible. A healthcare provider can perform a physical examination and order diagnostic tests such as an echocardiogram or electrocardiogram to confirm the diagnosis and determine the severity of the condition. Treatment for mitral valve stenosis may include medications to manage symptoms, lifestyle changes, or surgery to repair or replace the mitral valve. With timely and appropriate treatment, many people with mitral valve stenosis can lead active and fulfilling lives.

Treatment for rheumatic heart disease typically involves antibiotics to prevent further damage and medications to manage symptoms such as high blood pressure, swelling, and shortness of breath. In severe cases, surgery may be necessary to repair or replace damaged valves.

Prevention of rheumatic heart disease involves early diagnosis and treatment of rheumatic fever, as well as maintaining good cardiovascular health through a healthy diet, regular exercise, and not smoking.

Some common symptoms of rheumatic heart disease include:

* Shortness of breath
* Fatigue
* Swelling in the legs, ankles, and feet
* Chest pain or discomfort
* Dizziness or lightheadedness
* Irregular heartbeat

Some common risk factors for developing rheumatic heart disease include:

* Previous exposure to group A streptococcus bacteria, which can cause rheumatic fever
* Family history of rheumatic heart disease
* Poor living conditions or overcrowding, which can increase the risk of exposure to group A streptococcus bacteria
* Malnutrition or a diet low in certain nutrients, such as vitamin D and iron.

Types of congenital heart defects include:

1. Ventricular septal defect (VSD): A hole in the wall between the two lower chambers of the heart, allowing abnormal blood flow.
2. Atrial septal defect (ASD): A hole in the wall between the two upper chambers of the heart, also allowing abnormal blood flow.
3. Tetralogy of Fallot: A combination of four heart defects, including VSD, pulmonary stenosis (narrowing of the pulmonary valve), and abnormal development of the infundibulum (a part of the heart that connects the ventricles to the pulmonary artery).
4. Transposition of the great vessels: A condition in which the aorta and/or pulmonary artery are placed in the wrong position, disrupting blood flow.
5. Hypoplastic left heart syndrome (HLHS): A severe defect in which the left side of the heart is underdeveloped, resulting in insufficient blood flow to the body.
6. Pulmonary atresia: A condition in which the pulmonary valve does not form properly, blocking blood flow to the lungs.
7. Truncus arteriosus: A rare defect in which a single artery instead of two (aorta and pulmonary artery) arises from the heart.
8. Double-outlet right ventricle: A condition in which both the aorta and the pulmonary artery arise from the right ventricle instead of the left ventricle.

Causes of congenital heart defects are not fully understood, but genetics, environmental factors, and viral infections during pregnancy may play a role. Diagnosis is typically made through fetal echocardiography or cardiac ultrasound during pregnancy or after birth. Treatment depends on the type and severity of the defect and may include medication, surgery, or heart transplantation. With advances in medical technology and treatment, many children with congenital heart disease can lead active, healthy lives into adulthood.


Also known as: solar lentigo, senile lentigo, and lentigo simplex.

There are several types of heart septal defects, including atrial septal defects, ventricular septal defects, and mitral valve defects. Ventricular septal defects are the most common type and occur when there is an abnormal opening in the wall between the right and left ventricles.

Symptoms of heart septal defects can include shortness of breath, fatigue, and swelling in the legs and feet. In some cases, the defect may not cause any symptoms at all until later in life.

Diagnosis of heart septal defects is typically made using echocardiography, electrocardiography (ECG), or chest X-rays. Treatment options vary depending on the severity of the defect and can include medication to manage symptoms, surgery to repair the defect, or catheter procedures to close the opening. In some cases, heart septal defects may be treated with a procedure called balloon atrial septostomy, in which a balloon is inserted through a catheter into the abnormal opening and inflated to close it.

Prognosis for patients with heart septal defects depends on the severity of the defect and the presence of any other congenital heart defects. In general, early diagnosis and treatment can improve outcomes and reduce the risk of complications such as heart failure, arrhythmias, and endocardrial infection.

In summary, heart septal defects, ventricular type, are congenital heart defects that occur when there is an abnormal opening in the wall between the right and left ventricles of the heart. Symptoms can include shortness of breath, fatigue, and swelling in the legs and feet. Diagnosis is typically made using echocardiography, electrocardiography (ECG), or chest X-rays. Treatment options vary depending on the severity of the defect and can include medication, surgery, or catheter procedures. Prognosis is generally good for patients with heart septal defects if they receive early diagnosis and treatment.



Symptoms of endocarditis may include fever, fatigue, joint pain, and swelling in the legs and feet. In some cases, the condition can lead to serious complications, such as heart valve damage, stroke, or death.

Treatment for endocarditis typically involves antibiotics to clear the infection. In severe cases, surgery may be necessary to repair or replace damaged heart tissue. Preventive measures include good dental hygiene, avoiding risky behaviors such as injecting drugs, and keeping wounds clean and covered.

Endocarditis is a serious condition that can have long-term consequences if left untreated. Early diagnosis and treatment are essential to prevent complications and ensure the best possible outcome for patients.

www.medicinenet.com/sudden_death/article.htm
Sudden death is death that occurs unexpectedly and without warning, often due to a cardiac arrest or other underlying medical condition.

In the medical field, sudden death is defined as death that occurs within one hour of the onset of symptoms, with no prior knowledge of any serious medical condition. It is often caused by a cardiac arrhythmia, such as ventricular fibrillation or tachycardia, which can lead to cardiac arrest and sudden death if not treated promptly.

Other possible causes of sudden death include:

1. Heart disease: Coronary artery disease, heart failure, and other heart conditions can increase the risk of sudden death.
2. Stroke: A stroke can cause sudden death by disrupting blood flow to the brain or other vital organs.
3. Pulmonary embolism: A blood clot in the lungs can block blood flow and cause sudden death.
4. Trauma: Sudden death can occur as a result of injuries sustained in an accident or other traumatic event.
5. Drug overdose: Taking too much of certain medications or drugs can cause sudden death due to cardiac arrest or respiratory failure.
6. Infections: Sepsis, meningitis, and other severe infections can lead to sudden death if left untreated.
7. Genetic conditions: Certain inherited disorders, such as Long QT syndrome, can increase the risk of sudden death due to cardiac arrhythmias.

The diagnosis of sudden death often requires an autopsy and a thorough investigation into the individual's medical history and circumstances surrounding their death. Treatment and prevention strategies may include defibrillation, CPR, medications to regulate heart rhythm, and lifestyle modifications to reduce risk factors such as obesity, smoking, and high blood pressure.

Other cardiac abnormalities may be present, including aortic stenosis, or mitral valve prolapse. Abnormal genitalia: usually ...
MASS stands for: Mitral valve prolapse, Aortic root diameter at upper limits of normal for body size, Stretch marks of the skin ... Other possible symptoms are mitral valve prolapse, a large aortic root diameter, and myopia. The skeletal features found in ... mitral valve prolapse, loose or hypextensible joints, highly arched roof of the mouth, and mild dilatation of the aortic root. ... Individuals with MASS syndrome do not have progressive aortic enlargement or lens dislocation, while people with Marfan ...
This provides the explanation for the aortic aneurysms and prolapsed valves that are commonly associated with Marfan Syndrome. ... ß-blocker medication for aortic protection and prophylactic replacement of the aortic root. In MFS affected adults, it is ... The formation of the elastic fibers in the heart valves and the aorta require the involvement of both FBN-1 and FBN-2. It has ... These molecules interact to form the elastic fibers in the ventricularis layer of the semilunar valves. Fibrillin-1 and ...
In most instances some cusp stretching will be found which would result in prolapse and relevant regurgitation afterward if ... of the aortic valve. Thus, congenital aortic stenosis may be treated by aortic valve repair. In acquired aortic stenosis valve ... Aortic valve repair or aortic valve reconstruction is the reconstruction of both form and function of a dysfunctional aortic ... In most instances, aortic valve repair will be performed for aortic regurgitation (insufficiency). Aortic valve repair may also ...
... result from cystic medial degeneration of the valves, which is commonly associated with MFS (see mitral valve prolapse, aortic ... or leads to failure of the aortic or other valve, then surgery (possibly a composite aortic valve graft or valve-sparing aortic ... The signs of regurgitation from prolapse of the mitral or aortic valves (which control the flow of blood through the heart) ... The most serious complications involve the heart and aorta, with an increased risk of mitral valve prolapse and aortic aneurysm ...
Mitral Valve Prolapse murmur at mitral area Heart sounds of a 16-year-old girl diagnosed with mitral valve prolapse and mitral ... Stenosis of Bicuspid aortic valve is like the aortic valve stenosis heart murmur. But, one may hear a systolic ejection click ... Recorded with the stethoscope over the mitral valve. Mitral Valve Prolapse murmur at tricuspid area Her heart sounds while ... This will make murmurs in the mitral valve area more pronounced. Systolic Aortic valve stenosis is a crescendo/decrescendo ...
... mitral and aortic valve heart defects. A second genetic study specific to mitral valve prolapse focused on the PDGF signaling ... as these valves are often prolapsed or malformed as a symptom of EDS. Because hEDS is such a complex, multi-organ disease, ... such as mitral valve prolapse, creates an increased risk for infective endocarditis during surgery. This may progress to a life ... affecting aortic and mitral valves), skin problems such as hyperextensibility, atrophic scarring, thin skin, and easy bruising ...
... mitral valve prolapse, bicuspid pulmonary valve, hypoplastic transverse aortic arch, tricuspid valve regurgitation, right ... Other cardiac anomalies include mitral valve regurgitation, ...
... severe aortic valve stenosis (narrowing of the valve at the beginning of the aorta), pulmonary artery hypertension and a number ... aortic, tricuspid or pulmonary. Some types of valvular heart disease include valvular stenosis, valvular prolapse and ... Valvular heart disease is characterized by damage to or defective in one of the four heart valves: the mitral, aortic, ... Patient with native valve disease can often stop or reduce their anticoagulants, but those with prosthetic valves should not ...
... mitral valve prolapse, and a bicuspid aortic valve, and (3) atrial myxomas.[citation needed] Temporary vasospasm leading to ...
A bicuspid aortic valve (a type of congenital heart disease involving the aortic valve) is found in 7-14% of individuals who ... Alternatively, following an extensive intimal tear, the intimal flap may prolapse into the left ventricular outflow tract, ... Individuals who have undergone aortic valve replacement for aortic insufficiency are at particularly high risk because aortic ... preventing the leaflets of the valve from coapting. The dissection may extend into the aortic root and detach the aortic valve ...
Cocaine/marijuana toxicity and induced vasospasm Hypertrophic cardiomyopathy Valvular stenosis Mitral valve prolapse Aortic ...
... mitral valve prolapse, aortic valve disease, and atrial septal defect). In symptomatic cases, intravenous atropine or ...
Aortic Regurgitation Chapter 258: Mitral Stenosis Chapter 259: Mitral Regurgitation Chapter 260: Mitral Valve Prolapse Chapter ... 261: Tricuspid Valve Disease Chapter 262: Pulmonic Valve Disease Chapter 263: Multiple and Mixed Valvular Heart Disease Chapter ...
... facial dysmorphism facial hypotonia low posterior hairline short webbed neck low set ears mitral valve prolapse aortic valve ...
... progressive aortic root dilation, mitral valve prolapse, and mitral regurgitation Urogenital: Hirschsprung disease and ...
... ectopia lentis and heart complications such as mitral valve prolapse and aortic enlargement increasing the likelihood of aortic ... April 2006). "Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome". Science. 312 (5770): ...
Elongation of aorta Bicuspid aortic valve Subaortic stenosis Mitral valve prolapse with mitral regurgitation Atrial septal ... defect Patent ductus arteriosus Tricuspid valve prolapse Aortic dissection and aneurysm Aneurysm of ductus arteriosus These ...
Causes include mitral valve prolapse, tricuspid valve prolapse and papillary muscle dysfunction. Holosystolic (pansystolic) ... dilation of aortic root or pulmonary trunk, or structural changes in the semilunar valves without obstruction. Late systolic ... Many involve stenosis of the semilunar valves or regurgitation of the atrioventricular valves. Mid-systolic ejection murmurs ... Causes of midsystolic ejection murmurs include outflow obstruction, increased flow through normal semilunar valves, ...
All had severe eccentric mitral regurgitation (MR). (One had severe aortic regurgitation (AR) also.) One had flail posterior ... Mitral Valve Prolapse murmur at mitral area Heart sounds of a 16-year-old girl diagnosed with mitral valve prolapse and mitral ... "Mitral Valve Prolapse". The Lecturio Medical Concept Library. Retrieved 18 July 2021. Mitral Valve Prolapse at eMedicine " ... ISBN 978-0-615-15205-9. Scholia has a topic profile for Mitral valve prolapse. Mitral valve prolapse at Curlie (CS1 errors: ...
... heart valve prolapse MeSH C14.280.484.400.100 - aortic valve prolapse MeSH C14.280.484.400.500 - mitral valve prolapse MeSH ... aortic valve insufficiency MeSH C14.280.484.150 - aortic valve stenosis MeSH C14.280.484.150.060 - aortic stenosis, ... tricuspid valve prolapse MeSH C14.280.484.461 - mitral valve insufficiency MeSH C14.280.484.517 - mitral valve stenosis MeSH ... aortic aneurysm, thoracic MeSH C14.907.109.139.175 - aortic rupture MeSH C14.907.109.239 - aortic arch syndromes MeSH C14.907. ...
... aortic root dilatation and aneurysms, mitral valve prolapse, and abdominal wall hernias. Over 50% of patients with ADPKD ...
... mitral valve prolapse, hurler syndrome female gender "Mitral Annular Calcification: Background, Etiopathophysiology, ... aortic stenosis or hypertrophic cardiomyopathy abnormal calcium-phosphorus metabolism Chronic kidney disease/ESRD genetic ... As in most types of calcific valve disease, echocardiography plays the major role in detecting MAC and grading its severity and ... The overall prevalence of MAC is estimated at 10%. Interestingly, the two annuli of the mitral valve are not affected equally, ...
"Mitral Valve Prolapse", The Merck Manuals Online Medical Library, Retrieved 2011-01-08. "Aortic Stenosis - Cardiovascular ... Mitral valve prolapse: The click and the murmur of mitral valve prolapse are delayed because left atrial volume also increases ... The reason for this is that there is a larger pressure gradient across the aortic valve. A complementary maneuver for ... "Aortic Regurgitation". The Lecturio Medical Concept Library. October 2020. Retrieved June 29, 2021. Tanser, Paul H. (reviewed ...
Aortic valve repair Cardiac surgery Mitral valve insufficiency MitraClip Lewis, Sharon (2015). Medical-Surgical Nursing: ... Mitral Valve Prolapse, Functional MR, Cardiac Surgery, Degenerative MR, and Cardiomyopathy - Evalve, Inc Archived June 8, 2007 ... of the mitral valve. The mitral valve is the "inflow valve" for the left side of the heart. Blood flows from the lungs, where ... Not all damaged valves are suitable for repair; in some, the state of valve disease is too advanced and replacement is ...
... of the heart valves); for example, aortic valve insufficiency causes regurgitation through that valve, called aortic ... owing to insufficiency of the mitral valve; it may be acute or chronic, and is usually due to mitral valve prolapse, rheumatic ... of the tricuspid valve. Regurgitant fraction is the percentage of blood that regurgitates back through the aortic valve to the ... The various types of heart valve regurgitation via insufficiency are as follows: Aortic regurgitation: the backflow of blood ...
"Results of the First 158 Cases of Isolated Replacement of the Mitral and Aortic Valves in Jordan", Cardio-Pulmonary Medicine: ... "Clinical Non-Invasive and Invasive Findings in 50 Patients with Mitral Valve Prolapse". Non-Invasive Cardiovascular Diagnosis- ... "Gaucher's disease with valve calcification: Possible role of Gaucher cells, bone matrix proteins and integrins." Canadian ... Daoud Hanania performed the first open-heart surgery procedure in Jordan in 1970, the first heart-valve replacement in the ...
Atrioventricular valve Mitral Valve Prolapse murmur Heart sounds of a 16 year old girl diagnosed with mitral valve prolapse and ... as in mitral valve stenosis, tricuspid valve stenosis, pulmonary valve stenosis and aortic valve stenosis. Stenosis of the ... The other two valves are at the entrance to the arteries leaving the heart these are the semilunar valves - the aortic valve at ... For example, valvular disease of the aortic valve, such as aortic stenosis or aortic regurgitation, may cause breathlessness, ...
Patients with mitral valve prolapse may have a mid-systolic click along with a murmur, referred to as apical late systolic ... Aortic and pulmonary stenosis may cause an ejection click immediately after S1. MOUNSEY P (April 1953). "The opening snap of ... Hutter A, Dinsmore R, Willerson J, DeSanctis R (October 1971). "Early Systolic Clicks due to Mitral Valve Prolapse". ... These are short, high-pitched sounds.[citation needed] The mitral valve in cases of mitral stenosis may open with an opening ...
... Prolapse murmur Heart sounds of a 16 year old girl diagnosed with mitral valve prolapse and mitral regurgitation. ... where the mitral valve leaflet is contiguous with the posterior aortic root. During left ventricular diastole, after the ... The heart valves are all one-way valves allowing blood flow in just one direction. The mitral valve and the tricuspid valve are ... The mitral valve (/ˈmaɪtrəl/), also known as the bicuspid valve or left atrioventricular valve, is one of the four heart valves ...
He also focused his research on a new technique to replace the aortic valve, using autologous pericardium. Results of this ... new repair techniques such as the papillary muscle repositioning for anterior leaflet and posterior commissural prolapse. He ... one underwent isolated mitral valve repair, the other mitral valve repair associated to tricuspid valve repair. In this ... He also continued his research on mitral valve surgery and on tricuspid valve. In 2003, he presented a research paper at the ...
Acute aortic dissection can be difficult to diagnose but is more common than aortic aneurysm rupture. Thoracic aortic ... Veins have one-way valves that help blood flow toward the heart. If the valves are weak or damaged, blood can pool in veins, ... A common cause of damage to the nerve roots are lesions in the spine, such as prolapse of the nucleus pulposus, spinal ... Endovascular aortic repair (EVAR) refers to treatment of an abdominal aortic aneurysm, while thoracic endovascular aortic ...
By calculating the frequency shift of a particular sample volume, flow in an artery or a jet of blood flow over a heart valve, ... Gramiak, Raymond; Shah, Pravin M. (1968). "Echocardiography of the Aortic Root". Investigative Radiology. 3 (5): 356-66. doi: ... structures with other pelvic organs and it represents a useful hint to treat patients with symptoms related to pelvic prolapse ... The different detected speeds are represented in color for ease of interpretation, for example leaky heart valves: the leak ...
... syndrome Mitochondrial DNA depletion syndrome Mitochondrial neurogastrointestinal encephalopathy syndrome Mitral valve prolapse ... Acrocallosal syndrome Acropectoral syndrome Acro-dermato-ungual-lacrimal-tooth syndrome Activation syndrome Acute aortic ... syndrome Antiphospholipid syndrome Antisynthetase syndrome Antley-Bixler syndrome Anton-Babinski syndrome Aortic arch syndrome ...
Mitral valve prolapse murmur Heart sounds of a 16-year-old girl diagnosed with mitral valve prolapse and mitral regurgitation. ... It is caused by the closure of the semilunar valves (the aortic valve and pulmonary valve) at the end of ventricular systole ... aortic valve.[citation needed] Regurgitation through the aortic valve, if marked, is sometimes audible to a practiced ear with ... catching the pocket-like cusps of the aortic valve, and is stopped by aortic valve closure. Similarly, as the pressure in the ...
"Very long-term survival and durability of mitral valve repair for mitral valve prolapse". ACC Current Journal Review. 11 (2): ... This vortex rotates clockwise until the isovolumetric contraction of the left ventricle opens the aortic valve and redirects ... The mitral valve may need to be replaced because:[citation needed] The valve is leaky (mitral valve regurgitation) The valve is ... transcatheter mitral valve replacement involves wedging a new valve into the site of the existing valve. The replacement valve ...
Mitral Valve Prolapse murmur at mitral area Heart sounds of a 16-year-old girl diagnosed with mitral valve prolapse and mitral ... This method assumes that the aortic valve does not have aortic insufficiency.[citation needed] Another way to quantify the ... mitral valve replacement and mitral valve repair. Mitral valve repair is preferred to mitral valve replacement where a repair ... Recorded with the stethoscope over the mitral valve. Mitral Valve Prolapse murmur at tricuspid area Her heart sounds while ...
Aortic stenosis: This condition happens when the person has underlying congenital bicuspid valve, aortic sclerosis, or history ... Myocarditis Mitral valve prolapse syndrome: Those affected are usually slim females presented with chest pain which is sharp in ... Aortic aneurysm Asthma is a common long-term inflammatory disease of the airways of the lungs. It is characterized by variable ... Aortic dissection is characterized by severe chest pain that radiates the back. It is usually associated with Marfan's syndrome ...
Aortic aneurysm (ruptured) Abdominal aortic aneurysm Aortic dissection Bleeding Internal bleeding Hypovolemia Cardiac arrest ... Trauma center Emergency physician Emergency nurse Emergency medical technician Paramedic Emergency medical equipment Bag valve ... Ectopic pregnancy Eclampsia Pre-eclampsia HELLP syndrome Fetal distress Obstetrical bleeding Placental abruption Prolapsed cord ...
... mitral valve prolapse (episode 26) brain stem glioma (episode 27) pericardial effusion, cardiac rupture, subdural hemorrhage ( ... Diseases and surgeries included: tension pneumothorax (episode 1) cesarean section and aortic tear with post operative abscess ...
Pulsed-wave tissue Doppler can be used as a way to evaluate the severeness of arrhythmic mitral valve prolapse, by looking at ... hypertrophic cardiomyopathy and aortic stenosis, and may comprise as much as 50% of the total heart failure population. The ... and bileaflet mitral valve prolapse (BMVP). It's significant when exceeds 16 cm/s. The sudden systolic overload of which ... This is one of the risk markers for malignant arrhythmias in patients with myxomatous mitral valve disease (MMVD) ...
... by left ventricular outflow tract obstruction by a discrete ring or tunnel of fibrous tissue immediately below the aortic valve ... Cherry eye is the term used to refer to canine nictitans gland prolapse, a common eye condition in various dog breeds where the ... Heart valve dysplasia (including mitral and tricuspid valve dysplasia) is a congenital heart abnormality in dogs. Dysplasia of ... Most commonly the narrowing occurs at the pulmonary valve but it can also occur below the valve (subvalvular) or above the ...
About 10 to 20% of individuals with ostium secundum ASDs also have mitral valve prolapse. An ostium secundum ASD accompanied by ... This includes hypertension, which increases the pressure that the left ventricle has to generate to open the aortic valve ... Leachman R, Cokkinos D, Cooley D (1976). "Association of ostium secundum atrial septal defects with mitral valve prolapse". Am ... A layer of tissue called the septum primum acts as a valve over the foramen ovale during fetal development. After birth, the ...
In May 2017, the company acquired Symetis SA, a developer of minimally invasive transcatheter aortic valve implantation devices ... a type of surgical mesh used to treat pelvic organ prolapse. Experts concluded that the medical company had used cheap, ... TriVascular was founded in January 1998 to develop less-invasive medical devices and procedures for treating abdominal aortic ... In October Boston announced it had invested further in percutaneous mitral valve replacement system developer, MValve ...
Heart valves. Four heart valves - the aortic, mitral, pulmonary and tricuspid - keep the blood moving the right way. The valves ... A heart valve may become narrowed (stenosis), leaky (regurgitation or insufficiency) or close improperly (prolapse). ... Chambers and valves of the heart Enlarge image Close Chambers and valves of the heart. Chambers and valves of the heart. A ... The heart has four valves - the aortic, mitral, pulmonary and tricuspid valves. They open and close to move blood through the ...
Table 49: Transcatheter Aortic Valve Procedures, Billing and Reimbursement, U.S.. Table 50: Operations on Aortic Valve, ICD-10 ... Aortic Valve Area and Calcification Score, by Stage of Aortic Stenosis. Table 22: Global vs. U.S. Prevalence of Aortic Stenosis ... Table 29: Key Pipeline/R&D Products in Transcatheter Aortic Valve Treatment. Table 30: Mitral Valve Area, by Stage of Mitral ... Table 24: Imaging Techniques for Aortic Stenosis Diagnosis. Table 25: Types of Aortic Valve and Repair Techniques. Table 26: ...
... mitral valve prolapse, and partial systolic closure or coarse systolic fluttering of the aortic valve (see the image below). ... The waveform changes at the level of the aortic valve, but the systolic pressure does not change (arrow 2). Note the spike-and- ... The waveform changes at the level of the aortic valve, but the systolic pressure does not change (arrow 2). Note the spike-and- ... It may be associated with mitral valve prolapse (see the images below). ...
Aortic regurgitation is a heart valve disease in which the aortic valve does not close tightly. This allows blood to flow from ... Aortic valve prolapse; Aortic insufficiency; Heart valve - aortic regurgitation; Valvular disease - aortic regurgitation; AI - ... Surgery to repair or replace the aortic valve corrects aortic regurgitation. The decision to have aortic valve replacement ... Aortic regurgitation is a heart valve disease in which the aortic valve does not close tightly. This allows blood to flow from ...
Learn About The AdventHealth Heart Valve Surgery Clinic with Dr. Kevin Accola in Orlando, Florida ... In 2017, AdventHealth performed more than 865 valve surgery patients (aortic valve and mitral valve combined), more than anyone ... Hi there! My name is Denise Ring and I suffered from severe mitral regurgitation due to a mitral valve prolapse. Like many ... symptomatic aortic valve stenosis. Patients eligible for this therapy have severe aortic stenosis and are experiencing cardiac ...
... followed by patients with aortic bicuspid valves, mitral valve prolapse, and moderate mitral insufficiency (99,100). ... The mitral and aortic valves were most commonly affected. Patients often did not have a previous diagnosis of acute Q fever. ... Treatment should continue for at least 18 months for native valve infections and at least 24 months for prosthetic valve ... burnetii vascular infections reported in the literature are aortic infections, which complicate an aortic aneurysm or ...
Associations: aortic valve prolapse, pelvic and ability to develop cor pulmonale.. You need meticulous preparation, ideally ...
5.4.3. Mitral Valve Prolapse. 5.4.4. Aortic Stenosis. 5.4.5. Aortic Regurgitation ... PE: Systolic thrill and holosystolic murmur at lower sternal border, loud P2, S3, diastolic flow murmur across mitral valve ... PE:Prominent right ventricular impulse, wide fixed splitting of S2, systolic murmur from flow across pulmonic valve, diastolic ... PE: Loud P2, murmur of pulmonary valve regurgitation and signs of RV failure ...
Cardiovascular manifestations include MITRAL VALVE PROLAPSE; AORTIC ANEURYSM; and AORTIC DISSECTION. Other features include ... Cardiovascular manifestations include MITRAL VALVE PROLAPSE; AORTIC ANEURYSM; and AORTIC DISSECTION. Other features include ...
Mitral valve prolapse with slight reflux and dilatation of the aortic root. Myopia without retinopathy. Karyotype in peripheral ...
... hypoplastic tricuspid valve with a PDA (patent ductus artriosus); TOF (tetralogy of fallot); prolapse of aortic valve; and ... In one patient there was AVSD with right atrioventricular valve malformation with severe valve regurgitation and functional ... In addition; we described an unreported association with right atrioventricular valve malformation. Although there was a ...
New guidelines state that antibiotic premedication is no longer indicated for dental patients with mitral valve prolapse; ... bicuspid valve disease; calcified aortic stenosis; or congenital heart conditions, such as ventricular septal defects, atrial ... New guidelines state that antibiotic premedication is no longer indicated for dental patients with mitral valve prolapse; ... rheumatic heart disease; bicuspid valve disease; calcified aortic stenosis; or congenital heart conditions, such as ventricular ...
Pain from aortic or mitral valve prolapse, coronary artery spasm ie, variant angina and non-stemi patients. Calcitonin ... Mechanical obstruction must not be left unless they have coronary artery stenosis secondary to valve replacement is a common ... calcitonin-salmon, iu/kg im as a dilated, hypokinetic left ventricle mitral valve blood returns to more rapid than what is the ...
aortic regurgitation, mitral valve prolapse, or tricuspid regurgitation may be detected due to associated cardiac valve defects ... Aortic, mitral and tricuspid incompetence can be found in patients with autosomal dominant polycystic kidney disease. ... If the Korotkoff sounds do not disappear (e.g. patients with aortic valvular insufficiency or a high cardiac output) record ...
Query Trace: Mitral Valve Prolapse and MYLK[original query]. Recurrent germline mutations as genetic markers for aortic root ... dilatation in bicuspid aortic valve patients. Heart and vessels 2020 Oct . Wu Boting, Li Jun, Wang Yongshi, Cheng Yunfeng, Wang ...
... and crumpled ears in the absence of significant aortic root dilatation are characteristic of Beals syndrome and rarely found in ... of patients with MFS and the most common cardiovascular complications are dilatation of aortic root and mitral valve prolapse. ... Mitral valve prolapse can be seen among patients with FBN2 mutations. It has been previously suggested that congenital heart ... Other congenital heart defects have been reported, but aortic dilatation is mild in CCA and stationary, measurements being ...
... cardiologist ran a whole battery of tests and eventually concluded Heaven had an enlarged aortic root and mitral valve prolapse ...
For native valve endocarditis in the developed world, mitral valve prolapse is a common predisposing lesion. Other underlying ... Although the mitral valve is the most commonly affected site (followed by the aortic, tricuspid, and pulmonic valves), the ... bicuspid aortic valve), degenerative cardiac lesions (calcific aortic stenosis), and rheumatic heart disease. In developing ... Prosthetic valve endocarditis occurs in 1% to 4% of recipients during the first year following replacement and in approximately ...
Etiologies and Mechanisms of Mitral Valve Dysfunction 96. Mitral Valve Prolapse 97. Secondary Mitral Regurgitation 98. ... Aortic Stenosis Morphology 79. Quantification of Aortic Stenosis Severity 80. Aortic Stenosis: Risk Stratification and Timing ... Asymptomatic Severe Aortic Stenosis 85. Subaortic Stenosis Section XV Aortic Regurgitation 86. Aortic Regurgitation: Etiologies ... Stress Echocardiography for Valve Disease: Aortic Regurgitation and Mitral Stenosis 57. Stress Echocardiography: Comparison ...
mitral valve prolapse. *. rheumatic heart disease. *. bicuspid valve disease. *. calcified aortic stenosis ...
For expert diagnosis and treatment of heart valve disease, turn to the experienced doctors at The University of Vermont Medical ... Mitral valve prolapse can sometimes cause regurgitation.. *Aortic Valve Regurgitation - a problem with the aortic valve where ... treatment called Transcatheter Aortic Valve Replacement (TAVR), also known as Transcatheter Aortic Valve Implantation (TAVI). ... Aortic Stenosis - this type of valvular heart disease occurs when the aortic valve doesnt open enough and blocks blood flow. ...
... aortic stenosis, certain heart murmurs, and mitral valve prolapse with regurgitation are at greater risk of developing ... Infective endocarditis: People that have damaged heart valves, a history of rheumatic fever with subsequent heart valve damage ... infective endocarditis -- an infection of the lining and valves of the heart. ...
Mitral valve prolapse. *Rheumatic heart disease. *Bicuspid valve disease. *Calcified aortic stent ... the bacteria in the bloodstream could settle on susceptible areas such as prosthetic valves and so on. New evidence has found ...
... prolapse of an aortic cusp through a membranous ventricular septal defect, and a congenital aortic-left ventricular tunnel. ... In four cases the mycotic aneurysm was associated with bacterial endocarditis following aortic valve replacement, and in nine ... prolapse of an aortic cusp through a membranous ventricular septal defect, and a congenital aortic-left ventricular tunnel.", ... prolapse of an aortic cusp through a membranous ventricular septal defect, and a congenital aortic-left ventricular tunnel. ...
The four valves are tricuspid, pulmonary, mitral or aortic valves. Each valve has leaflets and flaps that open and close ... Valvular prolapse. *Valvular regurgitation. Why are cardiac surgeries best for you?. Both your life and its course may be ... Valve Replacement Surgery is where a malfunctioning valve is replaced with an artificial or biological valve (from pig, cow, or ... The two possibilities for heart valve surgery are as follows:. *Valve Repair Surgery fixes the malfunctioning valve while ...
2. Mitral Valve Prolapse. The mitral valve is present in the left side of the heart. When the flaps of this valve are floppy or ... 3. Aortic Regurgitation. In this scenario, there is a problem with the aortic valve and it does not close properly. This causes ... 4. Aortic Tear or Rupture. When there is tear or rupture in between layers of the walls of the aorta, it is called aortic ... it is referred to as Mitral valve prolapse. This causes irregular heartbeats, tachycardia and shortness of breath. There might ...
Mitral valve prolapse (30% in younger patients) d. Rheumatic heart disease (,20%) e. Calcific aortic stenosis (50% in older ... Abnormal valves b. Acute bacterial endocarditis i. Normal valves c. Prosthetic valvular endocarditis i. Within 1 year of valve ... Prosthetic valves 42. The valve most often affected by infective endocarditis is: a. Mitral b. Aortic c. Tricuspid d. Pulmonary ... IABP therapy is contraindicated for which of the following disorders? a. Papillary muscle rupture b. Incompetent aortic valve c ...
Transcatheter aortic valve replacement (TAVR) part I. Panelists: Aziz Ghaly, Ray Matthews, Firas Zahr DEBATE: TAVR-EMBOLIC ... severe A2 prolapse/flail: 1 or 2 clips? Marcella Calfon Press, MD... ... Transcatheter aortic valve replacement (TAVR) part II. TAVR DURABILITY, FAILURE MODES, AND TREATMENT OPTIONS Case presentation ... Transcatheter mitral valve repair / replacement part II. MITRA VALVE REPLACEMENT : TECHNOLOGY PIPELINE AND CASE STUDIES Tendyne ...
Senile calcific aortic stenosis with fusion of leaflets.. Sign out. AORTIC VALVE, REPLACEMENT: - BICUSPID AORTIC VALVE WITH ... 2001). "Floppy mitral valve/mitral valve prolapse/mitral valvular regurgitation: effects on the circulation.". J Cardiol 37 ... Biscupid aortic valve. General. *Aortic valve usually tricuspid.. *Most common congenital heart defect.[21] *1-2% of general ... Mostly those on the left side (subjected to higher pressures), i.e. mitral valve (or left atrioventricular v.) and aortic valve ...
  • [ 33 ] Patients with familial thoracic aortic aneurysm may have deformity of the thoracic cage (pectus excavatum, scoliosis). (medscape.com)
  • In addition, mutations in the TGF β R2 gene have been implicated as a rare cause (5%) of familial thoracic aortic aneurysm. (medscape.com)
  • In the course of his cardiology practice he encountered Marfan syndrome (first described by a French physician in 1896), a condition characterized by unusual height, abnormally long limbs, dislocation of the eye lenses, and aortic aneurysm and prolapsed heart valves, among other symptoms. (nih.gov)
  • Aortic aneurysm and dissection can be life threatening. (nih.gov)
  • Earned 'high performer' ratings in all 15 procedures and conditions - including cardiac bypass surgery, aortic valve surgery, abdominal aortic aneurysm repair, transcatheter aortic valve replacement(TAVR), heart attack and heart failure - evaluated in U.S. News ' 2021-2022 "Best Hospitals" study. (smh.com)
  • In some cases, the prolapsed valve lets a small amount of blood leak backward through the valve, called regurgitation, which may cause a heart murmur. (stroke.org)
  • The echo uses ultrasound to evaluate the characteristics of the valve cusps and how much blood may be leaking (regurgitation) from the valve when the heart contracts. (stroke.org)
  • When mitral valve prolapse is severe enough to cause significant valve leakage , called "regurgitation," it can lead to serious complications such as heart attack and stroke . (stroke.org)
  • Aortic regurgitation is a heart valve disease in which the aortic valve does not close tightly. (medlineplus.gov)
  • In the past, rheumatic fever was the main cause of aortic regurgitation. (medlineplus.gov)
  • Therefore, aortic regurgitation is more commonly due to other causes. (medlineplus.gov)
  • If your blood pressure is high, you may need to take blood pressure medicines to help slow the worsening of aortic regurgitation. (medlineplus.gov)
  • Surgery to repair or replace the aortic valve corrects aortic regurgitation. (medlineplus.gov)
  • People with angina or congestive heart failure due to aortic regurgitation do poorly without treatment. (medlineplus.gov)
  • You have symptoms of aortic regurgitation. (medlineplus.gov)
  • Blood pressure control is very important if you are at risk for aortic regurgitation. (medlineplus.gov)
  • Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE , leading to aortic regurgitation. (nih.gov)
  • Detailed description, including demographics and cost burden, of heart valve diseases (e.g., valvular stenosis and regurgitation) and transcatheter procedure approaches (e.g., transfemoral, transapical and transaortic). (researchandmarkets.com)
  • But, over time, aortic regurgitation became my new problem. (heart-valve-surgery.com)
  • My name is Denise Ring and I suffered from severe mitral regurgitation due to a mitral valve prolapse. (heart-valve-surgery.com)
  • This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. (justia.com)
  • Mitral regurgitation occurs when the native mitral valve fails to close properly and blood flows into the left atrium from the left ventricle during the systole phase of the cardiac cycle. (justia.com)
  • Mitral regurgitation has different causes, such as leaflet prolapse, dysfunctional papillary muscles, and/or stretching of the mitral valve annulus resulting from dilation of the left ventricle. (justia.com)
  • Many people with Marfan syndrome have additional heart problems including a leak in the valve that connects two of the four chambers of the heart (mitral valve prolapse) or the valve that regulates blood flow from the heart into the aorta (aortic valve regurgitation). (nih.gov)
  • Degenerative mitral valve disease is the most common cause of mitral regurgitation. (mitralvalverepair.org)
  • Dr. David H. Adams and his team offer patients a greater than 99 percent repair rate for patients with degenerative mitral valve regurgitation, and sets national benchmarks in safety. (mitralvalverepair.org)
  • 72-year-old male with a diagnosis of mitral valve prolapse and chronic severe mitral regurgitation, aortic root and ascending aorta dilatation and patent foramen ovale. (doctorsmedicalopinion.com)
  • At all ages, men are more likely than women to have certain heart valve conditions, such as aortic stenosis. (nih.gov)
  • This is similar to a procedure traditionally done in people with aortic stenosis. (medlineplus.gov)
  • To learn more about TAVR for patients with aortic stenosis, click here . (heart-valve-surgery.com)
  • AdventHealth Cardiovascular Institute has been selected as one of the first sites to offer the recently FDA-approved Edwards SAPIEN Transcatheter Aortic Valve Replacement (TAVR) as a treatment option for certain patients with inoperable, severe, symptomatic aortic valve stenosis. (heart-valve-surgery.com)
  • Patients eligible for this therapy have severe aortic stenosis and are experiencing cardiac symptoms such as shortness of breath, chest discomfort or syncope. (heart-valve-surgery.com)
  • I was born in 1967 with aortic stenosis. (heart-valve-surgery.com)
  • A failure of a valve to fully open, which restricts the amount of blood flow through the valve due to the thickening or stiffening of valves inside your heart may result in valve stenosis. (inlivepro.com)
  • Mechanical obstruction must not be left unless they have coronary artery stenosis secondary to valve replacement is a common underdiagnosed problem. (albionfoundation.org)
  • Other underlying structural factors include congenital defects (e.g., bicuspid aortic valve), degenerative cardiac lesions (calcific aortic stenosis), and rheumatic heart disease. (mhmedical.com)
  • Lifelong follow-up by echocardiography is advised, as aortic root dilatation can occur later in life. (medscape.com)
  • Patients may develop aortic dilatation. (medscape.com)
  • Echocardiography or cardiac MRI, to asses for valvular heart disease, mitral valve prolapse, aortic dilatation, or congenital abnormalities. (medscape.com)
  • Adults may have mitral valve prolapse or aortic root dilatation. (nih.gov)
  • Recurrent germline mutations as genetic markers for aortic root dilatation in bicuspid aortic valve patients. (cdc.gov)
  • Although the clinical features can be similar to Marfan syndrome (MFS), multiple joint contractures (especially elbow, knee and finger joints), and crumpled ears in the absence of significant aortic root dilatation are characteristic of Beals syndrome and rarely found in Marfan syndrome. (biomedcentral.com)
  • Lens subluxation is present in approximately half of patients with MFS and the most common cardiovascular complications are dilatation of aortic root and mitral valve prolapse. (biomedcentral.com)
  • Other congenital heart defects have been reported, but aortic dilatation is mild in CCA and stationary, measurements being always less than 2SD above mean [ 2 ]. (biomedcentral.com)
  • In MFS, the aortic root dilatation expands beyond 2SD and is progressive. (biomedcentral.com)
  • Mitral valve prolapse and bicuspid aortic valve problems can run in families. (nih.gov)
  • Mitral valve prolapse, also called MVP, is a condition in which the two valve flaps of the mitral valve don't close smoothly or evenly, but bulge (prolapse) upward into the left atrium. (stroke.org)
  • The native mitral valve of the human heart connects the left atrium to the left ventricle. (justia.com)
  • When operating properly, the anterior leaflet and the posterior leaflet function together as a one-way valve to allow blood to flow only from the left atrium to the left ventricle. (justia.com)
  • When the muscles of the left atrium relax and the muscles of the left ventricle contract, the increased blood pressure in the left ventricle urges the two leaflets of the mitral valve together, thereby closing the one-way mitral valve so that blood cannot flow back into the left atrium and is, instead, expelled out of the left ventricle through the aortic valve. (justia.com)
  • To prevent the two leaflets from prolapse under pressure and folding back through the mitral valve annulus towards the left atrium, a plurality of fibrous cords called chordae tendineae tether the leaflets to papillary muscles in the left ventricle. (justia.com)
  • Mitral valve vegetations are typically attached within 1-2 cm of the leaflet tip on the left atrial side and prolapse into the left atrium during systole. (mhmedical.com)
  • Mitral valve located between the left atrium and left ventricle. (inlivepro.com)
  • Learn about TAVR The AdventHealth Cardiovascular Institute maintains an experienced Transcatheter Aortic Valve Replacement (TAVR) Heart Team. (heart-valve-surgery.com)
  • The ECM component hyaluronan and TGFbeta2 are required for epithelial to mesenchymal transition (EMT) to contribute cardiac mesenchyme for heart valve formation and partitioning of the chambers. (nih.gov)
  • By contrast, infection of the cardiac valve leaflet endothelium (endocardium) is not rare and occurs even in the absence of identifiable preexisting valve disease. (mhmedical.com)
  • With our multi-disciplinary, team-based approach to cardiac care, patients benefit from collective expertise and decades of experience in evaluating and treating such conditions as irregular heartbeat, heart attack, heart failure, coronary artery disease, valve disorders, and other cardiovascular and thoracic disorders. (smh.com)
  • Even for those who aren't having symptoms, if a murmur is detected suggesting mitral valve prolapse, an echocardiogram (echo) is recommended. (stroke.org)
  • An echocardiogram uses sound waves to help diagnose mitral valve disease. (mitralvalverepair.org)
  • This helps prevent rheumatic fever , which can damage the heart valves. (nih.gov)
  • Problems with heart valves may occur as a result of infections (most commonly infective endocarditis and rheumatic fever), degeneration, or congenital abnormality. (singhealth.com.sg)
  • Mild aortic root enlargement has been reported, but further progression to dissection or rupture remains unclear. (medscape.com)
  • Stretching of the aorta may cause the aortic valve to leak, which can lead to a sudden tearing of the layers in the aorta wall ( aortic dissection ). (nih.gov)
  • Valvular heart disease is a disorder or disease of the heart valves, which are the tissue flaps that regulate the flow of blood into and out of the chambers of the heart. (singhealth.com.sg)
  • Patients with valvular heart disease have a malfunction of one or more of the heart valves. (singhealth.com.sg)
  • You may develop heart valve disease as you age, or because of medicine you take or a procedure you have. (nih.gov)
  • A family history of early coronary heart disease can also raise your risk of developing a heart valve disease. (nih.gov)
  • Risk factors for other types of heart disease may put you at risk for heart valve diseases, too. (nih.gov)
  • Your family history and the genes you inherit can increase your risk of developing a heart valve disease. (nih.gov)
  • You can take steps to help prevent some causes of congenital heart valve disease, although not all are preventable. (nih.gov)
  • The most common cause of MVP is abnormally stretchy valve leaflets (called myxomatous valve disease). (stroke.org)
  • Find out more about your heart valves and how to manage heart valve disease. (stroke.org)
  • According to the American Heart Association, approximately five million people are diagnosed with valve disease each year. (heart-valve-surgery.com)
  • Valve disease can develop before birth (congenital) or during one's life. (heart-valve-surgery.com)
  • These heart valves can be rendered less effective by congenital malformations, inflammatory processes, infectious conditions, or disease. (justia.com)
  • Valve infection probably begins when minor trauma, with or without accompanying valve disease, impairs the antihemostatic function of valve endocardium. (mhmedical.com)
  • Most cases of endocarditis occur in those with a predisposing structural abnormality (congenital or acquired), prosthetic valve, or a risk factor for disease (e.g., injection drug use, intravascular device, poor dental hygiene, chronic hemodialysis, human immunodeficiency virus infection). (mhmedical.com)
  • Although the mitral valve is the most commonly affected site (followed by the aortic, tricuspid, and pulmonic valves), the incidence of tricuspid valve endocarditis has steadily increased, attributed principally to increased rates of injection drug use. (mhmedical.com)
  • A sampling of his research work shows - 1973 angiomorphic correlation, 1974 pulmonic valve motion assessment, 1977 mitral valve prolapse, 1984 pulmonary and aortic assessment. (mcobajm.org)
  • The native heart valves (i.e., the aortic, pulmonary, tricuspid, and mitral valves) serve critical functions in assuring the forward flow of an adequate supply of blood through the cardiovascular system. (justia.com)
  • Doctor DeBoer was able to repair the aortic valve by simply cutting the three leaflets to a full open position. (heart-valve-surgery.com)
  • The mitral valve includes an annulus portion, which is an annular portion of the native valve tissue surrounding the mitral valve orifice, and a pair of cusps, or leaflets extending downward from the annulus into the left ventricle. (justia.com)
  • Infection usually first appears along the coapting surface of the leaflets, suggesting a role for valve opening and closing. (mhmedical.com)
  • The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. (nih.gov)
  • Aortic valve vegetations usually occur on the left ventricular (LV) side of the mid or distal portions of the aortic cusps and prolapse into the LV outflow tract during diastole. (mhmedical.com)
  • The decision to have aortic valve replacement depends on your symptoms and the condition and function of your heart. (medlineplus.gov)
  • There is increasing interest in a minimally invasive procedure in which a replacement valve is implanted via catheter. (medlineplus.gov)
  • AdventHealth Cardiovascular Institute (formerly Florida Hospital) excels at the repair and replacement of heart valves. (heart-valve-surgery.com)
  • For many years the definitive treatment for such disorders was the surgical repair or replacement of the valve during open-heart surgery. (justia.com)
  • Mitral valve replacement should not be an option. (mitralvalverepair.org)
  • The use of antibiotics before having a dental procedure is no longer recommended by the American Heart Association for patients with mitral valve prolapse, regardless of whether they have associated symptoms. (stroke.org)
  • Surgery can cure aortic insufficiency and relieve symptoms, unless you develop heart failure or other complications. (medlineplus.gov)
  • You have aortic insufficiency and your symptoms worsen or new symptoms develop (especially chest pain, difficulty breathing , or swelling ). (medlineplus.gov)
  • Your symptoms that you are experiencing may be due to the valve disorder you have. (inlivepro.com)
  • Aortic insufficiency is most common in men between the ages of 30 and 60. (medlineplus.gov)
  • Lab tests cannot diagnose aortic insufficiency. (medlineplus.gov)
  • This report is an analytical business tool with the primary purpose of providing a thorough evaluation of the global market for transcatheter treatment for heart valve diseases. (researchandmarkets.com)
  • Transcatheter edge-to-edge repair (TEER) of the mitral valve is a complex procedure requiring continuous image guidance with 2-dimensional and 3-dimensional transesophageal echocardiography. (bvsalud.org)
  • Leaks in these valves can cause shortness of breath, fatigue, and an irregular heartbeat felt as skipped or extra beats (palpitations). (nih.gov)
  • AdventHealth Cardiovascular Institute has assembled a special team of heart valve specialists that are committed to getting patients the best results. (heart-valve-surgery.com)
  • Such damage to the valves can result in serious cardiovascular compromise or death. (justia.com)
  • The cardiologist ran a whole battery of tests and eventually concluded Heaven had an enlarged aortic root and mitral valve prolapse. (thezippyzebra.com)
  • The individuals suffering from this condition typically suffer from an aortic valve that has just two flaps rather than three. (inlivepro.com)
  • These skeletal features are also seen in patients with bicuspid aortic valve sequence. (medscape.com)
  • 6. Increased prevalence of mitral valve prolapse in patients with migraine. (nih.gov)
  • 7. Mitral valve prolapse and platelet aggregation in patients with hemiplegic and non-hemiplegic migraine. (nih.gov)
  • In 2017, AdventHealth performed more than 865 valve surgery patients (aortic valve and mitral valve combined), more than anyone else in the state. (heart-valve-surgery.com)
  • The Center for Valve Therapies is a multidisciplinary clinic that combines the efforts of referring physicians, cardiologists, interventional cardiologists and cardiothoracic surgeons to provide focused assessments and treatment options for patients with complex valve disorders. (heart-valve-surgery.com)
  • Therefore, elderly and frail patients with defective heart valves often went untreated. (justia.com)
  • Pain from aortic or mitral valve prolapse, coronary artery spasm ie, variant angina and non-stemi patients. (albionfoundation.org)
  • The Mitral Valve Repair Center at Mount Sinai offers patients the highest percentage of mitral valve repair available anywhere in the world. (mitralvalverepair.org)
  • In a representative embodiment, a method comprises implanting first and second inflatable bodies within an annulus of a native heart valve by securing the inflatable bodies to tissue of the native heart valve with sutures, and implanting a prosthetic heart valve between the inflatable bodies such that the prosthetic heart valve is retained within the annulus by the inflatable bodies. (justia.com)
  • This happens because when the valve leaks, it can cause the atrium to enlarge. (stroke.org)
  • The second operation was carried out on Sept 12, 1957, with the patient under moderate total body hypothermia (29.5 C [85.1F]). A bulge was noticed just below the pulmonary valve and a thrill was pres- ent which was maximal over the bulge and extended up the pulmonary artery. (nih.gov)
  • 16. [Recurrent episodes of focal cerebral ischemia in a female patient with mitral valve prolapse and migraine headache]. (nih.gov)
  • When transient bacteremia coincides with the presence of an NBTE lesion, organisms may adhere to the valve leaflet and begin to proliferate causing additional deposition of platelets and fibrin and forming an infected vegetation. (mhmedical.com)
  • Vegetations begin near the coaptation line of the leaflet on the side that contacts the opposite leaflet during valve closure. (mhmedical.com)
  • Mitral valve repair is the recommended surgical therapy for all prolapsing degenerative mitral valves. (mitralvalverepair.org)
  • Recognized around the world for the volume of procedures performed, expertise and success, valve surgery has become a routine practice at our Institute. (heart-valve-surgery.com)
  • Heart valve surgery can be extremely complex and the experience of the entire team is critical. (heart-valve-surgery.com)
  • Aortic Valve Surgery in Non-Elderly Adults: What's New? (mitralvalverepair.org)
  • Otras características consisten en desplazamiento del cristalino (ectopia lentis), extremidades desproporcionadamente largas y engrosamiento de la DURAMADRE (ectasia dural). (bvsalud.org)
  • The mitral valve annulus can form a D-shaped, oval, or otherwise out-of-round cross-sectional shape having major and minor axes. (justia.com)
  • As a Valve Center of Excellence, AdventHealth is leading the field in ground-breaking techniques including minimally invasive and small incision. (heart-valve-surgery.com)
  • All prolapsing valves are repairable while using minimally invasive surgical techniques. (mitralvalverepair.org)
  • The pulmonary valve is located between the ventricle of the right as well as the blood vessels of the pulmonary circulation. (inlivepro.com)
  • Under inflow occlusion the prlmonary artery was opened, and by looking down through the pulmonary valve, a 5 mm defect could be seen high in the right ventricle im- mediately below the pulmonary valve. (nih.gov)
  • This can help protect you from infections that cause endocarditis, a type of heart inflammation that can damage the heart valves. (nih.gov)
  • For native valve endocarditis in the developed world, mitral valve prolapse is a common predisposing lesion. (mhmedical.com)
  • A chest X-ray chest, or an MRI may show an expanding heart, as well as a different ailments that could be connected to valves. (inlivepro.com)
  • NHLBI-supported researchers are investigating specific genes that can mutate and lead to heart valve defects such as bicuspid aortic valve syndrome. (nih.gov)
  • Mitral valve prolapse is also known as click-murmur syndrome, Barlow's syndrome or floppy valve syndrome . (stroke.org)
  • 12. Migraine and the mitral valve prolapse syndrome. (nih.gov)
  • This disorder does not allow your mitral valve to shut properly, which causes blood flow to flow back into the atrium left. (inlivepro.com)
  • The lub-dub sound is made by the heart valves closing as blood exits the heart chamber. (barkandwhiskers.com)
  • Dr. Adams and his team have been at the forefront of developing novel devices and approaches to facilitate mitral valve repair over the past decade. (mitralvalverepair.org)