A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Making an incision in the STERNUM.
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
An absorbable suture material used also as ligating clips, as pins for internal fixation of broken bones, and as ligament reinforcement for surgically managed ligament injuries. Its promising characteristics are elasticity, complete biodegradability, and lack of side effects such as infections.
A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.
Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.
Surgery performed on the heart or blood vessels.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
An abnormal balloon- or sac-like dilatation in the wall of AORTA.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
Surgery performed on the heart.
Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.
Operative procedures for the treatment of vascular disorders.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
The main trunk of the systemic arteries.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
An abnormal passage or communication between a bronchus and another part of the body.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
An infant during the first month after birth.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Surgical incision into the chest wall.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).
Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
A condition caused by occlusion of terminal aorta, the primary branches of the ABDOMINAL AORTA, as in aortoiliac obstruction. Leriche syndrome usually occurs in males and is characterized by IMPOTENCE, absence of a pulse in the femoral arteries, weakness and numbness in the lower back, buttocks, hips, and lower limbs.
Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Abnormal balloon- or sac-like dilatation in the wall of any one of the iliac arteries including the common, the internal, or the external ILIAC ARTERY.
Private, not-for-profit hospitals that are autonomous, self-established, and self-supported.
Care of patients by a multidisciplinary team usually organized under the leadership of a physician; each member of the team has specific responsibilities and the whole team contributes to the care of the patient.
Hospitals owned and operated by a corporation or an individual that operate on a for-profit basis, also referred to as investor-owned hospitals.
Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.
Services offered to the library user. They include reference and circulation.
Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty.

Inhibition of beta-myosin heavy chain gene expression in pressure overload rat heart by losartan and captopril. (1/563)

AIM: To study the effects of losartan and captopril on beta-myosin heavy chain (MHC), and alpha-MHC gene expression. METHODS: Pressure overload was produced by abdominal aortic coarctation (AAC) in rats. alpha- and beta-MHC mRNA were measured by Northern blot. RESULTS: In left ventricular myocardium of sham-operated rats, the alpha-MHC mRNA predominated, while the beta-MHC mRNA was only detectable. In response AAC, there was a 70-fold increase in the beta-MHC mRNA (P < 0.01), while alpha-MHC mRNA reduced to 26% (P < 0.01). Losartan (3 mg.kg-1.d-1, i.g. for 11 d) to AAC rats caused inhibitions of beta-MHC by 96% and alpha-MHC by 86% gene expression without lowering blood pressure. A reduction in beta-MHC mRNA was also seen in captopril-treated rats (30 mg.kg-1.d-1, i.g. for 11 d), but the inhibitory effect of captopril on alpha-MHC mRNA was less than that of losartan (44% vs 86%, P < 0.05). CONCLUSIONS: The shift of MHC isoform induced by pressure overload is due to up-regulation of beta-MHC and down-regulation of alpha-MHC gene expression. Inhibition of beta-MHC gene expression by losartan is achieved primarily by direct blockade of angiotensin II type I receptors in the myocardium, independent on hemodynamics.  (+info)

Biventricular repair approach in ducto-dependent neonates with hypoplastic but morphologically normal left ventricle. (2/563)

OBJECTIVES: Increased afterload and multilevel LV obstruction is constant. We assumed that restoration of normal loading conditions by relief of LV obstructions promotes its growth, provided that part of the cardiac output was preoperatively supported by the LV, whatever the echocardiographic indexes. BACKGROUND: Whether to perform uni- or biventricular repair in ducto dependent neonates with hypoplastic but morphologically normal LV (hypoplastic left heart syndrome classes II & III) remains unanswered. Echocardiographic criteria have been proposed for surgical decision. METHODS: Twenty ducto dependent neonates presented with this anomaly. All had aortic coarctation associated to multilevel LV obstruction. Preoperative echocardiographic assessment showed: mean EDLW of 12.4 +/- 3.03 ml/m2 and mean Rhodes score of -1.73 +/-0.8. Surgery consisted in relief of LV outflow tract obstruction by coarctation repair in all associated to aortic commissurotomy in one and ASD closure in 2. RESULTS: There were 3 early and 2 late deaths. Failure of biventricular repair and LV growth was obvious in patients with severe anatomic mitral stenosis. The other demonstrated growth of the left heart. At hospital discharge the EDLVV was 19.4+/-3.12 ml/m2 (p = 0.0001) and the Rhodes score was -0.38+/-1.01 (p = 0.0003). Actuarial survival and freedom from reoperation rates at 5 years were 72.5% and 46%, respectively. CONCLUSIONS: Biventricular repair can be proposed to ducto dependent neonates with hypoplastic but morphologically normal LV provided that all anatomical causes of LV obstruction can be relieved. Secondary growth of the left heart then occurs; however, the reoperation rate is high.  (+info)

A family study of coarctation of the aorta. (3/563)

Families of 100 patients with coarctation of the aorta and 50 controls for age, sex, and social status were studied to assess the influence of genetic and environmental variables in the aetiology. A tendency to familial aggregation of the condition and other congenital heart defects compatible with multifactorial inheritance was discerned. Recurrence risk for sibs is approximately 1 in 200 for coarctation of the aorta, and 1% for any form of congenital heart defect. The heritability of coarctation is estimated at 58%. The tendency for other non-cardiac defects to occur in the patients with coarctation does not appear in their sibs and is not so pronounced as in some other congenital heart conditions. Of the several environmental variables examined, there was no definitive association with any other than season of birth, which implies a possible association with maternal infection; there is also a suggestion of a paternal age effect, but these require investigation in a prospective survey.  (+info)

Long-term effects of balloon angioplasty on systemic hypertension in adolescent and adult patients with coarctation of the aorta. (4/563)

AIMS: To define the long-term effect of balloon angioplasty of aortic coarctation on hypertension, in adolescent and adult patients. METHODS: Balloon angioplasty of discrete, native aortic coarctation was performed on 50 patients (34 male) aged 23+/-8 (mean+/-standard deviation) years. In 42 of these patients cardiac catheterization and angiography were repeated 1 year later, and on the basis of sphygmomanometric blood pressure determination at that time, they were divided into 31 patients (group A) with normalized blood pressure and 11 patients (group B) who still needed antihypertensive medication. Both groups were followed annually thereafter for 12-123 (66+/-37) months. RESULTS: Coarctation gradient values before, immediately after and 1 year after angioplasty were 69+/-24 mmHg, 12+/-8 mmHg (P<0.001) and 7+/-6 mmHg. The corresponding systolic blood pressure values were 165+/-17 mmHg, 128+/-12 mmHg (P<0.001) and 115+/-10 mmHg (P<0.001) in group A; 182+/-21 mmHg, 141+/-24 mmHg (P<0.001) and 134+/-18 mmHg (P<0.001) in group B. Echocardiographic left ventricular mass index before angioplasty and at follow-up was 130+/-31 g x m-2 and 105+/-23 g x m-2 in group A; 157+/-38 g x m-2 and 132+/-35 g x m-2 in group B (P<0.001 for both comparisons). CONCLUSION: Normalization of blood pressure without medication occurred in 74% of patients after angioplasty for aortic coarctation, with subsequent long-term regression of left ventricular hypertrophy. In comparison to reported surgical results, balloon angioplasty should be considered as first line treatment for native, discrete aortic coarctation in adolescent and adult patients.  (+info)

Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses. (5/563)

We studied in anesthetized rats whether aminopeptidase P (AMP) may be involved in bradykinin (BK) metabolism and responses. For this we inhibited AMP with the specific inhibitor apstatin (Aps). Studies were done with Aps alone or together with the angiotensin-converting enzyme inhibitor lisinopril (Lis). Aps increased the vasodepressor response to an intravenous bolus of BK (400 ng/kg): vehicle, -3.0 +/- 0.7 mmHg; Aps, -7.8 +/- 0.7 mmHg (P < 0.01 vs. vehicle); Lis, -23.8 +/- 1.8 mmHg; Aps + Lis, -37.5 +/- 1.9 mmHg (P < 0.01 vs. Lis). Aps did not affect the vasodepressor response to BK given into the descending aorta. Plasma BK increased only in Aps + Lis-treated rats (in pg/ml): control, 48.0 +/- 1.4; Lis, 57.5 +/- 7.6; Aps + Lis, 121. 8 +/- 30.6 (P < 0.05 vs. control or Lis), whereas in rats infused with BK (400 ng. kg-1. min-1 for 5 min), Aps increased plasma BK (in pg/ml): control, 51.9 +/- 2.5; Aps, 83.5 +/- 20.5; Lis, 725 +/- 225; Aps + Lis, 1,668 +/- 318 (P < 0.05, Aps vs. control and Lis vs. Aps + Lis). In rats with aortic coarctation hypertension, the acute antihypertensive effects of Aps plus Lis were greater than Lis alone (P < 0.01). Hoe-140, a BK B2-receptor antagonist, abolished the difference. We concluded that in the rat AMP contributes to regulation of BK metabolism and responses.  (+info)

Critical pathways for postoperative care after simple congenital heart surgery. (6/563)

OBJECTIVE: To evaluate the clinical, financial, and parent/patient satisfaction impact of critical pathways on the postoperative care of pediatric cardiothoracic patients with simple congenital heart lesions. STUDY DESIGN: Critical pathways were developed by pediatric intensive care nurses and implemented under the direction of pediatric cardiothoracic surgeons. PATIENTS AND METHODS: Critical pathways were used during a 12-month study on 46 postoperative patients with simple repair of atrial septal defect (ASD), coarctation of the aorta (CoA), and patent ductus arteriosus (PDA). Using the study criteria, a control group of 58 patients was chosen from 1993. Prospective and control group data collected included postoperative intubation time, total laboratory tests, arterial blood gas utilization, morphine utilization, time in the pediatric intensive care unit, total hospital stay, total hospital charges, total hospital cost, and complications. Variances from the critical pathway and satisfaction data were also recorded for study patients. RESULTS: Resource utilization was reduced after implementation of critical pathways. Significant reductions were seen in total hours in the pediatric intensive care unit, total number of laboratory tests, postoperative intubation times, arterial blood gas utilization, morphine utilization, length of hospitalization (ASD, 4.9 to 3.1 days; CoA, 5.2 to 3.2 days; and PDA, 4.1 to 1.4 days; all P < 0.05), total hospital charges (ASD, $16,633 to $13,627; CoA, $14,292 to $8319; and PDA, $8249 to $4216; all P < 0.05), and total hospital costs. There was no increase in respiratory complications or other complications. Patients and families were generally satisfied with their hospital experience, including analgesia and length of hospitalization. CONCLUSIONS: Implementation of critical pathways reduced resource utilization and costs after repair of three simple congenital heart lesions, without obvious complications or patient dissatisfaction.  (+info)

Stent implantation in an adult with coarctation of the aorta in the presence of advanced secondary heart failure. (7/563)

We report the case of a 56-year-old woman with congenital coarctation of the aorta, who presented in critical clinical condition with advanced secondary cardiomyopathy and heart failure. We successfully applied an unusual technique to pass the aortic obstruction, and then implanted a PALMAZ stent. The procedure resulted in prompt clinical improvement and completely resolved the coarctation. The patient's improved clinical condition was still evident 11 months after the procedure.  (+info)

Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. (8/563)

It has been proposed that the macula densa participates in the regulation of increased renin expression in renovascular hypertension (RVH) and that prostaglandins may be among the mediators of macula densa function. We have previously shown that in renal cortex, cyclooxygenase-2 (COX-2) expression is localized to the macula densa and surrounding cortical thick ascending limb and increases in high-renin states, such as salt restriction and angiotensin-converting enzyme inhibition. In the present studies, we examined the effect of the selective COX-2 inhibitor SC58236 on plasma renin activity (PRA) and renal renin expression in RVH in rats. The aorta was coarcted between right and left renal arteries, and animals received either SC58236 or vehicle for 1 week. At day 8, vehicle-treated coarcted rats were hypertensive (mean carotid arterial blood pressure: 138+/-3 versus 87+/-2 mm Hg in sham-operated controls; n=9 to 11; P<0.001) and exhibited a disparity of kidney size (ratio left/right kidney: 0.78+/-0.04 versus 1.02+/-0.02; n=9 to 10; P<0.001). PRA increased significantly (84.6+/-6.5 versus 9.0+/-1.4 ng angiotensin I [Ang I] per milliliter per hour; n=8 to 9; P<0.01). In the coarcted rats, neither renin mRNA expression nor renin activity of the right kidney was altered (renin/GAPDH mRNA: 1.12+/-0.05-fold levels in control rats; n=6; P=NS; renin activity: 23.4+/-1.8 versus 27.1+/-3.4 ng Ang I per hour per milligram protein; n=8 to 9; P=NS). However, the renin mRNA of the left kidney increased to 3.0+/-0.6-fold of control (n=6), and the renin activity increased to 189.0+/-28.6 ng Ang I per hour per milligram protein (n=8; P<0.01). Expression of COX-2 mRNA and immunoreactive protein increased in the affected left kidney but was not different from control in the unaffected right kidney. SC58236 treatment to coarcted rats did not affect kidney size (ratio left/right kidney: 0.79+/-0.06; n=9). However, PRA was significantly decreased compared with the vehicle-treated coarcted rats (19.8+/-2. 8 ng Ang I per milliliter per hour; n=9; P<0.01). The left kidney renin mRNA and renin content were also decreased (1.7+/-0.3-fold control; n=6; P<0.05; and 45.7+/-7.6 ng Ang I per hour per milligram protein; n=9; P<0.01, respectively), while renin mRNA and renin content of the right kidney were not altered. SC58236 lowered mean arterial blood pressure (122+/-5 mm Hg; n=14; P<0.05 compared with vehicle). A significant correlation was observed between PRA and mean blood pressure (r=0.75; P<0.01). In summary, these studies indicate that the selective COX-2 inhibitor SC58236 decreases renin production and release in RVH and suggest an important role for COX-2 regulation of the renin-angiotensin system.  (+info)

Figure 1: Enlarged MRA Pre and post stenting of coarctation. Perspective: Coarctation of the aorta is a relatively common defect that occurs in approximately 6-8 % of patients with congenital heart disease and is commonly associated with a bicuspid aortic valve. Intravascular stents are finding increased applications in the treatment of patients with native coarctation of the aorta and percutaneous intervention is a reasonable alternative to surgical correction. 4D flow MR imaging has shown promise in the evaluation of both the clinical significance of the coarctation through the demonstration of collateral blood flow and the persistence of helical flow after coarctation repair ...
Double orifice mitral valve is a rare congenital anomaly presenting as the division of the mitral orifice into two anatomically distinct orifices, it is most often associated with other congenital heart defects such as left-sided obstructive lesions, ventricular septal defects or aortic coarctation. We report the case of a 15 years old boy, admitted for arterial hypertension, auscultation revealed a rude aortic systolic murmur. Femoral pulses were weak. Owing to the suspicion of aortic coarctation, transthoracic echocardiography was performed, the aortic coarctation with dilation of the aorta proximal to the stenosis was confirmed and bicuspid aortic valve was found with good function. The mitral valve was dysmorphic, having two orifices; it was divided into 2 separate valve orifices by a fibrous bridge. No mitral or aortic regurgitation was documented by color Doppler flow imaging. The left ventricular ejection fraction was normal. There was a small peri membranous ventricular septal defect with left
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TY - JOUR. T1 - Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload. AU - Yamashita, Yoshiyuki. AU - Tatewaki, Hideki. AU - Matsumoto, Takashi. AU - Shiose, Akira. PY - 2018/10/1. Y1 - 2018/10/1. N2 - A 13-year-old girl, who had undergone interrupted aortic arch repair with an 8-mm graft as a neonate and Fontan completion in childhood, developed ventricular fibrillation due to long-QT syndrome. Cardioverter defibrillator implantation was planned. Preoperative catheterization showed a 45-mmHg aortic pressure gradient and ventricular end-diastolic pressure of 11 mmHg. This indicated that recurrent coarctation had adversely affected ventricular function. After consideration of the patients age, symptoms and anatomical/surgical complexities, axillo-iliac bypass with cardioverter defibrillator implantation was performed. Postoperative ventricular end-diastolic pressure was 6 mmHg. Axillo-iliac bypass is a surgical option for coarctation that can reduce cardiac ...
Pressure and flow were recorded in the ascending aorta of three dogs with aortic coarctation, induced surgically 3 months previously, and in three control litter mates. From these data were derived input impedance of the systemic circulation, pulsatile and steady components of external heart work, aortic systolic pressure-time index, and mean systolic and mean diastolic pressures. Results were correlated with intraoperative measurements of aortic pressure in three young patients with aortic coarctation and with records taken in another 24 patients during diagnostic catheterization. Distinctive changes in aortic impedance with coarctation were explained in terms of altered peripheral reflection. Such changes were responsible for characteristic alteration in central aortic pressure pulse contour and for change in other parameters, indicating impaired arterial function in accepting pulsatile flow from the heart. Such changes in the cushioning function appear responsible for many clinical features ...
TY - JOUR. T1 - Management of arch hypoplasia after successful coarctation repair. AU - DeLeon, Maryann M.. AU - DeLeon, Serafin Y.. AU - Quinones, Jose A.. AU - Roughneen, Patrick. AU - Magliato, Kathy E.. AU - Vitullo, Dolores A.. AU - Cetta, Frank. AU - Bell, Timothy J.. AU - Fisher, Elizabeth A.. PY - 1997. Y1 - 1997. N2 - Background. Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a somewhat hypoplastic arch to grow or from clamp injury at the time of the initial repair, or from both causes. Because of mediastinal adhesions and minimal collateral circulation, use of extraanatomic bypass grafts appears to be the preferred approach. Methods. Six children or young adults presented with arch obstruction over a 3-year period. Their mean age was 13.5 ± 4 years, and the mean interval from the time of the initial repair was 10 ± 4 years. The mean age of the patients at the time of the initial repair was 3.2 ± 5 years. ...
TY - JOUR. T1 - Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta. T2 - An observational study by the CCISC (Congenital cardiovascular interventional study consortium). AU - Forbes, Thomas J.. AU - Kim, Dennis W.. AU - Du, Wei. AU - Turner, Daniel R.. AU - Holzer, Ralf. AU - Amin, Zahid. AU - Hijazi, Ziyad. AU - Ghasemi, Abdolrahim. AU - Rome, Jonathan J.. AU - Nykanen, David. AU - Zahn, Evan. AU - Cowley, Collin. AU - Hoyer, Mark. AU - Waight, David. AU - Gruenstein, Daniel. AU - Javois, Alex. AU - Foerster, Susan. AU - Kreutzer, Jacqueline. AU - Sullivan, Nancy. AU - Khan, Asra. AU - Owada, Carl. AU - Hagler, Donald. AU - Lim, Scott. AU - Canter, Joshua. AU - Zellers, Thomas. PY - 2011/12/13. Y1 - 2011/12/13. N2 - Objectives: The purpose of this study was to compare the safety and efficacy of surgical, stent, and balloon angioplasty (BA) treatment of native coarctation acutely and at follow-up. Background: Controversy surrounds the optimal ...
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Arterial hypertension remains a common problem after coarctation repair, and is a major concern in the long-term outcome of these patients. The pathophysiology of hypertension after successful surgical treatment of aortic coarctation, and in the absence of re-coarctation is still poorly understood. It has been suggested that coarctation of the aorta could represent a primary or secondary systemic vasculopathy rather than an isolated local disease of the aortic isthmus. These changes are thought to be involved in the development of hypertension in the absence of re-coarctation as well as premature cardiovascular events.. A number of observational studies in patients after coarctation repair have proposed endothelial dysfunction as measured by FMD, or a decreased reactivity to nitric oxide of the arterial wall as a key player in this respect.3 ,19-22 Impairment of FMD in these patients has been described with20 and without evidence of increased blood pressures.3 This has lead to the hypothesis ...
Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. The word coarctation means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with coarctations. Other heart defects may also occur when coarctation is present, typically occurring on the left side of the heart. When a patient has a coarctation, the left ventricle has to work harder. Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood through the aorta to deliver blood to the lower part of the body. If the narrowing is severe enough, the left ventricle may not be strong enough to push blood through the coarctation, thus resulting in lack of blood to the lower half of the body. Physiologically its complete form is manifested as interrupted aortic arch.[citation ...
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Pseudocoarctation is a rare congenital anomaly characterized by aorta elongation and kinking, without significant obstruction. We report the case of an elderly patient with history of congestive heart failure (CHF) and aortic regurgitation (AR) who was referred for progressive exertional dyspnoea. After multimodal imaging evaluation, aortic coarctation with significant trans-stenosis gradient but mild luminal narrowing was diagnosed; this borderline patient was not addressed to repair, according to ESC guidelines and in spite of AHA ones. He rather met the criteria for pseudocoarctation diagnosis. An integration of functional and anatomical data is essential for a reliable diagnostic process in similar cases.
PURPOSE: To show that 4D Flow is a clinically viable tool for evaluation of collateral blood flow and demonstration of distorted blood flow patterns in patients with treated and untreated aortic coarctation.. MATERIALS AND METHODS: Time-resolved, 3D phase contrast magnetic resonance imaging (MRI) (4D Flow) was used to assess blood flow in the thoracic aorta of 34 individuals: 26 patients with coarctation (22 after surgery or stent placement) and eight healthy volunteers.. RESULTS: Direct comparison of blood flow calculated with 2D and 4D phase contrast data at standard levels for analysis in coarctation patients showed good correlation and agreement (correlation coefficient r = 0.99, limits of agreement = -20% to 20% for collateral blood flow calculations). Abnormal blood flow patterns were demonstrated at peak systole with 4D Flow visualization techniques in the descending thoracic aorta of patients but not volunteers. Marked helical flow was seen in 9 of 13 patients with angulated aortic arch ...
The long-term outlook for children who have had their coarctation repaired, either with surgery or angioplasty, is excellent. Children who have successful repair of coarctation usually can live full and productive lives. Women usually can become pregnant safely. However, medical problems can occur after repair.. Recoarctation. Recoarctation is the redevelopment of a narrowing in the aorta. This problem occurs more commonly in children who have had their coarctation repaired during the first year of life. Recoarctation occurs in approximately 10% to 20% of children who have had their repair in infancy, and in less than 3% of children who have had their repair after 3 years of age. Treatment of recoarctation of the aorta usually is with a balloon angioplasty.. High blood pressure. High blood pressure is one of the most common medical problems seen in patients after successful repair of coarctation. Approximately 60% of people who have had their coarctation repaired will require medication to treat ...
TY - JOUR. T1 - Coarctation of the aorta. T2 - Lifelong surveillance is mandatory following surgical repair. AU - Brown, Morgan L.. AU - Burkhart, Harold M.. AU - Connolly, Heidi M.. AU - Dearani, Joseph A.. AU - Cetta, Frank. AU - Li, Zhuo. AU - Oliver, William C.. AU - Warnes, Carole A.. AU - Schaff, Hartzell V. PY - 2013/9/10. Y1 - 2013/9/10. N2 - Objectives The objective of our study was to review the long-term outcomes of patients undergoing surgical repair of aortic coarctation. Background Surgical repair of aortic coarctation has been performed at the Mayo Clinic, Rochester, Minnesota, for over 60 years. Methods Between 1946 and 2005, 819 patients with isolated coarctation of the aorta underwent primary operative repair. Medical records were reviewed and questionnaires mailed to the patients. Results Mean age at repair was 17.2 ± 13.6 years. The majority (83%) had pre-operative hypertension. Operations included simple and extended end-to-end anastomosis (n = 632), patch angioplasty (n = ...
Children beyond infancy are usually asymptomatic and are most often diagnosed because of a murmur or hypertension on a routine examination[1]. Delayed or absent femoral pulses and an arm/leg systolic blood pressure difference of 20 mm Hg or more in favor of the arms may be considered as evidence for aortic coarctation[3].. The coarctation can be demonstrated on suprasternal notch two-dimensional echocardiographic views along with increased Doppler flow velocity across the coarctation site[1]. Cardiac catheterization reveals significant systolic pressure gradient (, 20 mm Hg) across the coarctation and angiography demonstrates the degree and type of aortic narrowing[3].. Surgical relief of coarctation may be achieved by resection and end-to-end anastomosis or by subclavian flap or prosthetic path angioplasty[1]. Elective repair of isolated aortic coarctation is nowadays indicated at 3-6 months of life or at the time of diagnosis[2]. Complications, such as recoarctation or secondary hypertension, ...
To the Editor:. Using percutaneous catheter techniques and endovascular grafts, Ince et al1 reported successful treatment of aneurysms occurring after previous repair of aortic coarctation with no mortality and minimal morbidity in 6 patients. They contrasted these results with those reported for similar patients with open surgical treatment, in whom the mortality rates ranged between 14% and 23.5%. The 3 references reporting these outcomes were published between 1989 and 1996.. Any comparison of these 2 methods of treatment for recurrent aneurysm after coarctation repair should include contemporary reports that use modern surgical techniques. Two recent studies using the technique of full cardiopulmonary bypass and circulatory arrest in 9 patients with complications following surgical repair of aortic coarctation (including 7 patients with aneurysms or pseudoaneurysms) reported no early deaths and few major complications.2,3. Although minimally invasive endovascular techniques offer important ...
The patient was a 19 year-old woman with the diagnosis of resistant hypertension, although she was under treatment of three classes of anti-hypertensive drugs (beta blocker, angiotensin receptor blocker, diuretic) for more than one year. In physical examination there was only a significant difference between the systolic blood pressure of upper and lower extremities (200 vs. 120 mmHg), without any other remarkable finding. Three different imaging modalities (echocardiography (Figure 1), CT angiography (Figure 2), conventional aortography (Figure 3) confirmed the aortic coarctation at 30 mm after left subclavian artery origin, with the 3.5-4 mm diameter of the narrowest segment. She underwent implantation of a self-expanding aortic stent and therefore the systolic pressure gradient decreased from 90 to 15 mmHg. After three months, her blood pressure was stable on 110/80 mmHg, while she received only metoprolol 25 mg twice daily and follow-up echocardiography showed 15-20 mmHg pressure gradient through
Background. Dacron patch aortoplasty repair of coaretation of the aorta carries an inherent risk of aneurysm development. Sudden death from aortic rupture prompted discontinuing this operation and evaluating 39 patients (16 girls; mean age 6.3 years, range 10 days to 14.5 years) undergoing repair between January 1976 and October 1987. The aorta ruptured in 10 patients; 6 died at a mean interval of 8.1 years (range 0.75 to 12.4) after repair. All 33 survivors were interviewed and examined. ...
Peak ascending and descending aortic blood flow velocities were measured using continuous wave Doppler ultrasound velocimetry in 30 children with coarctation or recoarctation of the aorta and in 13 control subjects. The results were compared with the arm to leg systolic blood pressure difference. The peak flow velocities in the descending aorta were significantly higher in the patients than in the control subjects and there was a close correlation with the systolic blood pressure gradient. Since there was no overlap of flow velocities between the patients and the control subjects the Doppler technique enables coarctation confidently to be excluded as well as demonstrating its presence and severity. The method is simple, rapid, independent of the condition of the aortic valve, and is applicable to neonates in whom the diagnosis of coarctation may otherwise be difficult. In older children it is useful for detecting recoarctation and following its progress, particularly in patients in whom a ...
Surgical strategy and approach are important in patients with aortic coarctation associated with intracardiac anomalies. In this study, surgical technique, indications and results of the single stage repair of aortic coarctation and intracardiac defects via median sternotomy were discussed. Between January 1987 and August 2002, 158 patients with aortic coarctation or interrupted aortic arch (IAA) underwent surgery. In 17 of them who had associated intracardiac anomalies, single stage approach via median sternotomy were performed. Their ages ranged from 1 month to 13 years (mean 2.2 3.3 years). Ventricular septal defect (VSD) and aortic stenosis were the most common associated lesions. Aortic coarctation was repaired under cardiopulmonary bypass initially and then intracardiac repair was performed. A short period of total circulatory arrest was necessary in two patients with IAA and one patient with extensive arcus hypoplasia. Among the patients who underwent single stage repair of aortic ...
Hypoplastic infrarenal aorta or infrarenal aortic coarctation is an uncommon vascular pathology characterized with diffuse stenosis in the infrarenal abdominal aorta. It is a variant of atherosclerotic occlusive diseases. The exact incidence and etio
To assess the effects on the biosynthesis of collagen types I and III associated with an acute increase in blood pressure, we established a mid-thoracic aortic coarctation in the rabbit and studied gene expression and protein accumulation of these collagen types proximal to the stenosis 1, 3 and 7...
Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at JFK Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at Grand Strand Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at TriStar Centennial Parthenon Pavilion DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
In this report 5 patients between the ages of 5-14 years admitted to the Department of Pediatric Cardiology, Hacettepe University, and diagnosed as having pseudocoarctation of the aorta arc presented. The clinical and angiographic findings of this rare abnormality of childhood are discussed, the importance of differential diagnosis of this entity from coarctation of the aorta is emphasized, and the literature reviewed. © 1990, International Heart Journal Association. All rights reserved ...
TY - JOUR. T1 - Impact of treatment modality on vascular function in coarctation of the aorta. T2 - The LOVE-COARCT study. AU - LOVE-COARCT Study. AU - Martins, José D.. AU - Zachariah, Justin. AU - Tierney, Elif Seda Selamet. AU - Truong, Uyen. AU - Morris, Shaine A.. AU - Kutty, Shelby. AU - de Ferranti, Sarah D.. AU - Guarino, Maria. AU - Thomas, Boban. AU - Oliveira, Diana. AU - Marinho, António. AU - António, Marta. AU - Gauvreau, Kimberlee. AU - Jalles, Nuno. AU - Geva, Tal. AU - Carmo, Miguel M.. AU - Prakash, Ashwin. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Background-Optimally treated patients with coarctation of the aorta remain at risk for late vascular dysfunction. The effect of treatment modality on vascular function is unknown. The LOVE-COARCT (Long-term Outcomes and Vascular Evaluation After Successful Coarctation of the Aorta Treatment) study was done to compare vascular function in patients with coarctation of the aorta treated with surgery, balloon dilation (BD), or stent ...
Looking for Coarctation of aorta? Find out information about Coarctation of aorta. A compression of the wall of a vessel, narrowing the lumen and reducing the volume . A stricture or occlusion resulting from an outside force deforming a vessel Explanation of Coarctation of aorta
Catheter Cardiovasc Interv. 2014 Jun 1;83(7):1124-30. doi: 10.1002/ccd.25318. Epub 2014 Jan 6. Research Support, Non-U.S. Govt
Pseudocoarctation of the aorta is a very rare anomaly characterized by kinking or buckling of the descending aorta at the level of the ligamentum arteriosum without a pressure gradient across the lesion. Pathology It is thought to be of congeni...
Coarctation of the aorta (CoA) is a congenital abnormality producing obstruction to blood flow through the aorta. Coarctation can occur in isolation, in association with bicuspid aortic valve or with major cardiac malformations. CoA accounts for 5-8% of the 8/1000 (4-6/10,000) children born with congenital heart disease. Most CoA is newly diagnosed in childhood; , 25% recognized beyond 10 yrs.. CoA is mostly repaired in childhood by surgery or by balloon catheter dilation. Recurrence rates range from 5-20%. Recurrence is often not recognized until adolescence. Balloon expandable stents have become the predominant therapy in the USA and Europe for CoA treatment in this age group. There are no FDA approved stents for this use. Biliary stents are currently being used off label. Enrollment into a trial of bare metal Cheatham Platinum (CP) Stents, designed for use in CoA, is completed. The Coarctation of the Aorta Stent Trial (COAST) aims to confirm safety and efficacy of CP Stent for native and ...
Coarctation of the aorta: Find the most comprehensive real-world symptom and treatment data on coarctation of the aorta at PatientsLikeMe. 13 patients with coarctation of the aorta experience fatigue, depressed mood, pain, anxious mood, and insomnia.
Coarctation of the aorta is a common heart defect present at birth.. With this defect, a portion of the large blood vessel that carries blood from the heart to the rest of the body (aorta) is abnormally narrowed or pinched. Coarctation of the aorta makes it harder for the heart to pump blood to the body. Over time, this can lead to high blood pressure, heart failure, or other complications.. This condition is usually detected in newborns during normal blood pressure checks and by listening to the heart. Further tests, such as echocardiography, may be done to confirm the diagnosis.. Coarctation of the aorta requires repair by surgery or heart catheterization.. ...
Looking for online definition of aortic coarctation in the Medical Dictionary? aortic coarctation explanation free. What is aortic coarctation? Meaning of aortic coarctation medical term. What does aortic coarctation mean?
Looking for online definition of coarctation of the aorta in the Medical Dictionary? coarctation of the aorta explanation free. What is coarctation of the aorta? Meaning of coarctation of the aorta medical term. What does coarctation of the aorta mean?
The case of a 25-year-old woman with coarctation of the thoracic aorta and combined bilateral fibromuscular dysplasia of the renal arteries is reported. Although marked hemodynamic changes induced by the coarctation were probably pre-existent, hypertension was revealed only during the last month of her first pregnancy and was spontaneously corrected 2 months post partum. Surgical treatment of the thoracic coarctation did not influence blood pressure which remained normal ...
TY - JOUR. T1 - Long-term Follow-up of Simple Lesions-Atrial Septal Defect, Ventricular Septal Defect, and Coarctation of the Aorta. AU - Goldberg, Jason. PY - 2015/9/1. Y1 - 2015/9/1. N2 - Surgery for congenital heart disease has advanced significantly in the past 50 years, such that repair of simple lesions, such as atrial septal defect, ventricular septal defect, and coarctation of the aorta carries minimal risk, with mortality risk much less than 1%. It was once thought successful repair of these lesions was definitively corrective. There is mounting evidence, however, that there are long-term complications after these repairs, prompting the need for continued follow-up. This review describes the current understanding of diagnosis, treatment, and long-term outcomes for these patients, with the goal of advocating for lifelong surveillance. As the perioperative care of these repairs has evolved significantly over time, so must the way in which we study these patients in the ...
Bicuspid aortic valves (BAVs) represent a wide morphologic and functional spectrum. In coarctation of the aorta, BAVs are common, but the proportion of BAV subtypes and their relation to aortic dimensions and development of late valve dysfunction are unknown. Sixty-two cardiovascular magnetic resonance investigations of patients with coarctation of the aorta were reviewed with respect to aortic valve morphology, aortic valve function, and aortic dimensions. BAVs were identified in 45 patients (72.6 %), of which 13 (20.9 %) were type-0 (two commissures), 28 (45.1 %) type-1 (three commissures but fusion of one commissure with a raphe) and 4 (6.5 %) valves were bicuspid but not possible to classify further. Patients with BAVs type-0 had larger dimensions in their sinus of Valsalva (35.5 ± 6.8 vs. 29.7 ± 2.7 mm, p = 0.002), ascending aorta (33.1 ± 6.2 vs. 26.0 ± 4.3 mm, p = 0.005) and sino-tubular junction (29.3 ± 7.4 vs. 24.2 ± 3.5 mm, p = 0.040) compared with tricuspid aortic valves (TAVs). ...
TY - GEN. T1 - Growth effects of anastomosis site on patient-specific aortic hemodynamics after coarctation correction. T2 - 10th Asian Control Conference, ASCC 2015. AU - Mao, Le. AU - Zhang, Weimin. AU - Hong, Haifa. AU - Sun, Qi. AU - Huang, Junrong. AU - Liu, Jinfen. AU - Liu, Jinlong. AU - Zhu, Zhongqun. AU - Qian, Yi. AU - Wang, Qian. AU - Umezu, Mitsuo. PY - 2015/9/8. Y1 - 2015/9/8. N2 - Coarctation of the aorta (CoA) is one of the most common congenital cardiac anomalies that could be corrected by surgery. However, the effects of surgical anastomosis on aortic arch flow are still unknown. In this study, a unique three-dimensional way was utilized to measure the growth of anastomotic site and computational fluid dynamics (CFD) was applied to investigate the hemodynamic effects of the growth of anastomosis site on patient-specific aortic arch flow before, 1 year and 2 years after surgery. The volume of anastomotic site, distribution of total pressure, wall shear stress (WSS), streamlines, ...
Coarctation of the aorta blood pressure is a narrowing of the aorta that causes pressure changes. Learn about coarctation of the aorta treatments here at Ohio State.
This is the official website of Razi Journal of Medical Sciences published by Tehran University of Medical Sciences.The Razi Journal of Medical Sciences (RJMS) is the scientific medical journal of Iran, which has been published from 1993 onward in Persian with abstract of English language (former Journal of Iran University of Medical Sciences). Although it had been published quarterly in the past, RJMS has been published monthly (12 issues per year) from the year 2009. The Razi Journal of Medical Sciences, a scientific and research peer reviewed journal, seeks to publish original papers, selected review articles and case reports. RJMS also seeks to provide its readers with the highest quality materials published through a process of careful double-blind peer reviews and editorial comments. RJMS is an official publication of the Tehran University of Medical Sciences.
Coarctation of the aorta is a congenital defect affecting blood flow from the heart. Learn more from Boston Childrens Hospital.
The U.S. Food and Drug Administration (FDA) recently approved the NuMED Cheatham Platinum (CP) Stent System for the prevention and/or treatment of aortic wall injury (AWI) in patients with coarctation of the aorta involving a compliant aortic isthmus or first segment of the descending aorta where there is adequate size and patency of at least one femoral artery and balloon angioplasty is contraindicated or predicted to be ineffective.. Stent therapy for coarctation of the aorta offers a non-surgical alternative to traditional operative repair of the aortic obstruction with similar results and complication rates. Stent treatment also has a lower rate of recurrence and aortic wall injury compared to balloon dilation alone.. Covered stent therapy provides similar outcomes and allows for simultaneous treatment of aortic wall injuries, such as aneurysm and pseudo-aneurysm that might be present, related to previous surgical or catheter based therapy of the coarctation. In the COAST II clinical trial, ...
Assess ventricular function, volumes and LV mass (may be increased 2° LVOTO or hypertension). Measure peak CoA velocity, look for diastolic prolongation of forward flow Fig. 1. Contrast-enhanced axial CT showing a transverse fracture through the mid-portion of a coarctation stent. There is a residual moderate coarctation, and marked dilatation of the descending thoracic aorta Fig. 2. Volume rendered 3D reconstruction of a contrast-enhanced CT angiogram showing a coarctation stent with mild residual narrowing (arrow). A) b-SSFP image oblique coronal view, showing narrow jet of moderate aortic regurgitation. (b) b-SSFP images showing a 4-Ch view of a dilated left ventricle in a patient with aortic regurgitation 18 a Aortic Valve Incompetence c 500 Normal Mild AR Moderate AR 400 Severe AR b Flow volume (mL/s) 300 200 100 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 -100 Time frames -200 Fig. 2. Aortic regurgitation phase contrast velocity mapping, (a) magnitude image aortic valve, (b) phase contrast ...
1) Short stature. 2) Web neck ( Extra folds of skin on the neck). 3) Low hairline at the back of the neck. 4) Low-set ears. 5) Infections of the middle ear (otitis media) usually in infants. There is a documented relationship between Turner syndrome and sensorineural hearing loss in adults.. 6) Puffiness or swelling (lymphedema) of the neck, hands and feet.. 7) Broad shield shaped thorax and widely spaced nipples.. 8) Poor breast development. 9) Skeletal abnormalities including cubitus valgus (elbow deformity), scoliosis, short 4th metacarpal. 10) Narrow fingernails and toenails that are turned upward.. 11) Primary amenorrhea.. 12) Infantile external genitalia. 13) Ovaries severely atrophied and fibrous (streak ovaries). 14) Congenital heart disease, particularly aortic coarctation (narrowing of the large artery). 15) The incidence of aortic dissection is extremely common and occurs early in life and in pregnancy. 16) Skin changes, including an increased number of melanocytic nevi, hypertrophic ...
Single ventricle with systemic obstruction in early life: comparison of initial pulmonary artery banding versus the Norwood operation.: PAB+/-coarctation repair
To investigate the relation of pressure and vascular wall thickening in hypertension, we coarcted the abdominal aorta upstream to the renal arteries in 14 rats. Sham-coarcted (n = 16) and two-kidney, one-clip (Goldblatt) hypertensive rats (n = 13) served as controls. Tail, femoral, and carotid arterial pressures rose (p less than 0.01) in the two-kidney, one-clip hypertensives; only carotid pressure rose (p less than 0.01) in the coarcted rats, tail and femoral pressures remaining normal (p greater than 0.25). Thus, the hindquarters of the coarcted rats remained normotensive. Four to six weeks after surgery we perfusion-fixed vascular tissues of the hindquarters, including kidneys, with formalin at in vivo levels of pressure. Glycol methacrylate-embedded tissues were sectioned at 1 micron thickness and vessels quantitatively evaluated. The outer medial and lumen perimeters of abdominal aorta, femoral artery, and renal arterioles were measured; from these measurements, vessel outer and lumen ...
Anatomic aortic anomalies are seen in many medical conditions and are known to cause disturbances in blood flow. Turner syndrome (TS) is a genetic disorder occurring only in females where cardiovascular anomalies, particularly of the aorta, are frequently encountered. In this study, numerical simulations are applied to investigate the flow characteristics in four TS patient- related aortic arches (a normal geometry, dilatation, coarctation and elongation of the transverse aorta). The Quemada viscosity model was applied to account for the non-Newtonian behavior of blood. The blood is treated as a mixture consisting of water and red blood cells (RBC) where the RBCs are modeled as a convected scalar. The results show clear geometry effects where the flow structures and RBC distribution are significantly different between the aortas. Transitional flow is observed as a jet is formed due to a constriction in the descending aorta for the coarctation case. RBC dilution is found to vary between the ...
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A child with neurofibromatosis and hypertension also demonstrated renal artery stenosis, the most common cause of hypertension in children with neurofibromatosi
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Our site may use order forms to allow users to request information, products, and services.. Your Doctors Right to Privacy. We will respect your doctors right to privacy. A doctor typically does not give his/her e-mail address to the parents/guardians of patients. We will not provide the e-mail addresses of doctor(s) in the local practice to users of their site without the doctor(s) permission. Their site is restricted to use by whomever they wish, and they may deny access to their site to one or more prior users. In unusual cases, doctors may change their private sites access code and arrange for us to e-mail the new access code to approved users.. Cookies. We use cookies to deliver content specific to your interests and to save your doctors access code so you dont have to re-enter it each time you visit your doctors site on http://www.remedyconnect.com.. Links. This site contains links to other sites. RemedyConnect.com is not responsible for the privacy practices or the content of such ...
Structural Heart Disease Australia is an incorporated association focused on education in valvular and structural cardiac diseases. It was started by group of echocardiographers, anaesthetists, clinical and interventional cardiologists, and cardiothoracic surgeons to provide a useful learning resource for medical professionals.. ...
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Background Despite a?successful repair procedure for coarctation of the aorta (CoA), up to two-thirds of patients remain hypertensive. of antihypertensive medication, invasive peak-to-peak systolic pressure on the arch, and aortic diameters on three-dimensional angiography. Data on follow-up were obtained in the date of most recent outpatient check out. Results Twelve individuals underwent stenting of the aortic arch. Mean follow-up period was 14??11?weeks. Mean peak-to-peak gradient across the arch decreased from Midecamycin 39??13?mm?Hg to 7??8?mm?Hg directly after stenting (= em radius?a???radius?b??? /em . Stent implantation technique All methods were performed under general anaesthesia. In all individuals, vascular access was accomplished using the right femoral artery. The DynaCT Artis Zee system (Siemens Healthcare, Erlangen, Germany) was utilized for carrying out three-dimensional rotational angiography. The three-dimensional reconstructions gathered with this system were used as an ...
On what basis do you make the claim that DNA has mistakes galore, miscopies, additional sequences not found in the original, entire pieces cut out, crossovers, and yet, the organism still lives, still REPRODUCES AND HAS VIABLE OFFSPRING? You obviously know nothing about benefits. My youngest daughter was born 2 years ago. We had no indication of any problems throughout the duration of the pregnancy. 30 minutes after she was delivered, she was taken to the nursury. My wife and I were notified minutes later that she was on an ambulance being rushed to a heart specialist. We soon found out she has Turner Syndrome; she is missing a chromosome. We spent 2 weeks in the NICU unit, sleeping in the waiting room after she underwent a balloon procedure to reduce the pressure gradient at her aortic valve. The valve is bicuspid, and a coarctation of her aorta was also compounding the problem. After letting her go home for a month, we then spent another month in ICU after she underwent open heart surgury. ...
The diagnostics of congenital heart disease, and especially the need for frequent lifelong postoperative follow-up examinations, require an imaging modality as gentle and reliable as possible. The method commonly used for this purpose ? echocardiography - is associated with some disadvantages, especially in older patients with an insufficient acoustic window. For these patients magnetic resonance imaging (MRI) is an alternative imaging modality. The aim of this study was to evaluate two functional MR methods, flow measurement with a flow phantom and ventricular function analysis in comparison to 3D echocardiography. These methods were performed in 6 different groups of patients with uncorrected or surgically corrected congenital heart diseases. 1. Beside a good correlation between the estimated pressure gradients in the area of stenoses and re-stenoses in patients with coarctation with the aid of MR flow measurements, three-dimensional reconstruction from MR angiography (MRA) data supplies ...
Our son, Tyson Hugh Hooper, was born with coarctation of the aorta, hypoplastic arch, and a transitional avsd. His first open heart surgery reconstructed his aorta and was on day 9 of life. His second open heart repair was not anticipated to be needed until two or three years of age. Ty had other plans. We spent the vast majority of his first 3 months of life at Vanderbilt as he went into heart failure and was diagnosed with pulmonary hypertension. As a result, the medical team concluded that he needed the repair much sooner than usually recommended, and at just shy of 3 months old Ty underwent his second life saving open heart surgery. God has already worked so many miracles in Tys life and the life of our family and we know he is using our story. Because of this, we are grateful for Tys special heart and feel beyond blessed that God chose us to travel this road. We ask for prayers as Ty continues to heal. We are praying for a full recovery and life without restrictions for Ty. We are praying ...
Our son, Tyson Hugh Hooper, was born with coarctation of the aorta, hypoplastic arch, and a transitional avsd. His first open heart surgery reconstructed his aorta and was on day 9 of life. His second open heart repair was not anticipated to be needed until two or three years of age. Ty had other plans. We spent the vast majority of his first 3 months of life at Vanderbilt as he went into heart failure and was diagnosed with pulmonary hypertension. As a result, the medical team concluded that he needed the repair much sooner than usually recommended, and at just shy of 3 months old Ty underwent his second life saving open heart surgery. God has already worked so many miracles in Tys life and the life of our family and we know he is using our story. Because of this, we are grateful for Tys special heart and feel beyond blessed that God chose us to travel this road. We ask for prayers as Ty continues to heal. We are praying for a full recovery and life without restrictions for Ty. We are praying ...
Dr.Sanjeeb Roy at Fortis, Jaipur. Call +911414097109 with one of the best cardiologist in India. He maintains his interest in non-coronary interventions with weekly cases of balloon dilatations of valves (mitral, aortic, pulmonary), dilatation and stenting of Coarctation, devices closures of...
The team jumped right in and did a fabulous job. But were always gerry rigging something or moving onto PLAN B (or as Spongebobs nemesis would say, PLAN Z). Its great to work with such resourceful, CAN DO, NO IS NOT AN OPTION, types....The second suprise came today when we added on a Coarcation repair that was seen at Tuesdays Clinic by Dr Sable. For some reason, they dont see coarctations here in Uganda, so we decided to show them.....AND the super suprise was a baby seen on monday with Transposition (and PS/SUB PS) who had O2 sats of 40...we put together the necessary equipment to bring him into the CICU, intubate, line him, and Dr Sable performed a life saving balloon Septostomy. While this buys him some time, surgery is the only long term survival option. Unfortunately, this is NOT something that can be done at this stage of the program here in Uganda. Were still working on options ...
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The secretary at my work is actually allergic to most scents (including deodorants, shampoos, etc) and can get hospitalized if its bad enough. She can smell a perfume or cologne a mile away. Luckily Im not often in the office, but when I am I have to be very mindful. How would you guys try to avoid getting cologne on your clothes? Currently it seems the cologne gets mostly on my undershirt and not my dress shirt. Was wondering if anyone had any other tricks
"Atypical Infrarenal Aortic Coarctation", J. Vasc. Surg. Cases Innov. Tech, 2017. "Carotid Axillary Artery Bypass: An Option ...
... best known for performing the first successful repair of aortic coarctation on 19 October 1944, one year before Robert E. Gross ... the first to repair aortic coarctation". Ann. Thorac. Surg. Netherlands. 87 (1): 342-6. doi:10.1016/j.athoracsur.2008.08.072. ...
Various congenital vascular malformations cause SSS, examples including aortic coarctation and interrupted aortic arch. ... "Diagnosis of subclavian steal in infants with coarctation of the aorta and interruption of the aortic arch by color-coded ... one example being the obstructive fibrosis or thrombosis resulting from repair of aortic coarctation. Another example is ... "Cerebrovascular abnormalities in postoperative coarctation of aorta. Four cases demonstrating left subclavian steal on ...
Aortic valve stenosis Supravalvar aortic stenosis Coarctation of the aorta Hypoplastic left heart syndrome Bashore TM (2007). " ... may be due to a defect in the aortic valve, or a defect located at the subvalvar or supravalvar level. ...
Some of these hearts also had overt congenital anomalies, especially aortic stenosis and coarctation of the aorta.[citation ... "Early fetal endocardial fibroelastosis and critical aortic stenosis: a case report" Ultrasound Obstet Gynecol 5: 202-205. ...
Causes of inferior rib notching by etiology: Arterial: aortic coarctation, aortic thrombosis, pulmonary-oligemia/arteriovenous ... Inferior rib notching can be associated with aortic coarctation (as a result of dilatation of intercostal arteries), superior ... LearningRadiology.com > Coarctation Of the Aorta Retrieved August 2010 "Medcyclopaedia - Rib notching". Retrieved 2010-04-15.. ...
Left anterior thoracotomy Isolated pulmonary artery banding (PAB) Left lateral thoracotomy PAB (when coarctation or aortic arch ... "aortic translocation and biventricular outflow tract reconstruction." The repair consisted of harvesting the aortic root from ... The main thing is the repositioning of the native aortic root over to the LV cavity, avoiding the creation of a long tortuous ... Bex who introduced the possibility of aortic translocation in 1980. But Nikaidoh has put the procedure in practice in 1984. It ...
Right-sided aortic arch Patent ductus arteriosus Coarctation of the aorta Diagram showing the origins of the main branches of ... A double aortic arch; occurs with the development of an abnormal right aortic arch in addition to the left aortic arch, forming ... They are ventral to the dorsal aorta and arise from the aortic sac. The aortic arches are formed sequentially within the ... The aortic arches or pharyngeal arch arteries (previously referred to as branchial arches in human embryos) are a series of six ...
If this does not occur, this can result in coarctation of the aorta. The ductus arteriosus connects to the final section of the ... The aortic knob is the prominent shadow of the aortic arch on a frontal chest radiograph. Aortopexy is a surgical procedure in ... The aortic arch, arch of the aorta, or transverse aortic arch (English: /eɪˈɔːrtɪk/) is the part of the aorta between the ... At this point the aortic arch continues as the descending aorta. The aortic arch has three branches. The first, and largest, ...
... as in the operation for patent ductus arteriosus or coarctation). After pulling the left lung aside, the layer (mediastinal ... Double aortic arch with right dominant arch: Normally there is only one (left) aortic arch. In patients with double aortic arch ... Double aortic arch is a subtype of complete vascular ring. There are three types of double aortic arch: Right dominant arch ( ... Double aortic arch is a relatively rare congenital cardiovascular malformation. DAA is an anomaly of the aortic arch in which ...
In a sense it is the complete form of a coarctation of the aorta. Almost all patients also have other cardiac anomalies, ... Rarely, an interrupted aortic arch can be associated with an intracranial aneurysm. Signs of ischemia due to interrupted aortic ... Interrupted aortic arch (especially Type B) is often associated with DiGeorge syndrome. Patients with an interrupted aortic ... They are: Type A: The aortic arch is interrupted after the left subclavian artery. Type B: The aortic arch is interrupted ...
... coarctation of aorta, hypoplastic left heart syndrome, anomalous aortic origin of a coronary artery among others. Approximately ... Anomalous aortic origin of a coronary artery History: The Congenital Heart Surgeons Society Data Center. Caldarone CA, Williams ...
However, TIAs can result from emboli in calcific aortic disease and aortic coarctation. Spinal arteriovenous malformations ( ... or aortic dissection (a tear in the aorta). Anterior spinal artery syndrome is necrosis of tissue in the anterior spinal artery ...
Complex aortic root replacements have also been performed routinely. Surgical correction of extremely rare conditions (like ... Repair of Fallot's Tetralogy • PDA • Surgery for Coarctation of aorta • PA banding • Right Heart bypass in univentricular heart ... Valve replacements and repair • Surgery for aortic dissection and aneurysms. • Repair of atrial and ventricular septal defects ...
In 1950 Karreman underwent experimental heart surgery for an aortic coarctation at the University of Chicago. He married Anneke ...
... coarctation of the aorta, critical aortic stenosis, and interrupted aortic arch). ...
If this does not occur, this can result in coarctation of the aorta.[11][12] The ductus arteriosus connects to the final ... For the embryological structure, see Aortic arches.. The aortic arch, arch of the aorta, or transverse aortic arch (English: / ... Aortic arch. The aortic arch has three branches, the brachiocephalic trunk, left common carotid artery, and left subclavian ... The aortic knob is the prominent shadow of the aortic arch on a frontal chest radiograph.[14] ...
Aortic coarctation and aortic stenosis are both forms of aortic narrowing. In terms of word root meanings, the names are not ... and recoarctation in elective aortic coarctation repair. Including long-term results after elective aortic coarctation repair ... The word "coarctation" means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with ... This spectrum is dichotomized by the idea that aortic coarctation occurs in the aortic arch, at or near the ductus arteriosis, ...
Aortic coarctation - pre-ductal, post-ductal. *Aortic dissection. *Aortic stenosis. *Aortitis, inflammation of the aorta that ... Aortic archEdit. Main article: Aortic arch. The aortic arch loops over the left pulmonary artery and the bifurcation of the ... Between the aortic arch and the pulmonary trunk is a network of autonomic nerve fibers, the cardiac plexus or aortic plexus. ... The left aortic sinus contains the origin of the left coronary artery and the right aortic sinus likewise gives rise to the ...
Coarctation of the aorta (CoA). *Double aortic arch, aberrant subclavian artery, and other malformations of the great arteries ... Common defects include pulmonic stenosis, aortic stenosis, and coarctation of the aorta, with other types such as bicuspid ... For another member of the gene family, mutations in the Notch1 gene are associated with bicuspid aortic valve, a valve with two ... Notch1 is also associated with calcification of the aortic valve, the third most common cause of heart disease in adults.[20][ ...
Surgery in great vessels (aortic coarctation repair, Blalock-Taussig shunt creation, closure of patent ductus arteriosus) ... Once you're training for the speciality, you may choose to subspecialise in perhaps: aortic surgery; adult cardiac surgery; ... Crafoord C, Nyhlin G. Congenital coarctation of the aorta and its surgical management J Thorac Surg 1945;14:347-361. ... Aortic Surgery, Thoracic Surgery, Pediatric Cardiac Surgery or Cardiac ICU. Contemporary Canadian candidates completing general ...
Coarctation of the aorta. *Interrupted aortic arch. *Double aortic arch. *Right-sided aortic arch ...
... congenital aortic stenosis), or the main blood vessels that lead from the heart (e.g. coarctation of the aorta). More complex ... pulmonary veins) → left atrium (atrial appendage) → mitral valve → left ventricle → aortic valve (aortic sinus) → (aorta and ... The left ventricle pumps blood to the body through the aortic valve and into the aorta. Two small openings above the aortic ... The semilunar aortic valve is at the base of the aorta and also is not attached to papillary muscles. This too has three cusps ...
C: Catecholamines, Coarctation of the Aorta, Cushing's Syndrome. *D: Drugs, Diet. *E: Erythropoietin, Endocrine Disorders [61] ... torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva ...
Coarctation of the aorta is also a known risk factor,[5] as is arteriovenous malformation.[7] Genetic conditions associated ... torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva ...
It is normally less than 10 mm Hg,[26] but may be increased in e.g. coarctation of the aorta.[26] ... of exercise-induced arm-leg blood pressure gradient and abnormal arterial compliance in patients with repaired coarctation of ...
... coarctation of the aorta, single ventricle heart disease, abnormalities of the pulmonary veins, atrial septal defect, ... Aortic valve repair. *Aortic valve replacement *Ross procedure. *Percutaneous aortic valve replacement ...
Hypoplastic infrarenal aorta or infrarenal aortic coarctation is an uncommon vascular pathology characterized with diffuse ... Aortic Coarctation / diagnosis*, surgery. Aortography. Blood Vessel Prosthesis Implantation. Diagnosis, Differential. ... Here, we report a 49-year-old male patient diagnosed with abdominal aortic coarctation together with the review of the ... 20223618 - Technique of interventional repair in adult aortic coarctation.. 20347698 - Treatment of a pelvic arteriovenous ...
Coarctation of the aorta is a common congenital cardiovascular defect characterized by upper-body hypertension resulting from ... encoded search term (Aortic%20Coarctation%20Imaging) and Aortic Coarctation Imaging What to Read Next on Medscape. Related ... is diagnostic of aortic coarctation. It is the result of obstruction of blood flow at the narrowed aortic segment, in ... Aortic Coarctation Imaging. Updated: Nov 24, 2015 * Author: Vibhuti N Singh, MD, MPH, FACC, FSCAI; Chief Editor: Eugene C Lin, ...
Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
... disrupts aortic blood flow in a region and physiological manner akin to aortic coarctation in humans. Here we use a whole- ... Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.. Peterson RT, Shaw SY, Peterson TA, ... organism, phenotype-based, small-molecule screen to discover a class of compounds that suppress the coarctation phenotype and ...
Results were correlated with intraoperative measurements of aortic pressure in three young patients with aortic coarctation and ... Influence of Aortic Coarctation on Pulsatile Hemodynamics in the Proximal Aorta. MICHAEL F. OROURKE, TIMOTHY B. CARTMILL ... Distinctive changes in aortic impedance with coarctation were explained in terms of altered peripheral reflection. Such changes ... Pressure and flow were recorded in the ascending aorta of three dogs with aortic coarctation, induced surgically 3 months ...
What Is Aortic Coarctation?. Coarctation of the aorta (CoA) is a congenital malformation of the aorta. The condition is also ... Aortic Coarctation. Coarctation of the aorta is a congenital malformation of the aorta in which part of the aorta is ... What Causes Aortic Coarctation?. CoA is one of several common types of congenital heart malformations. CoA may occur alone. It ... How Is Aortic Coarctation Diagnosed?. A newborns first examination will usually reveal CoA. Your babys doctor may detect ...
Learn more about Aortic Coarctation -- Adult at JFK Medical Center DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
Aortic wall injury might include: Descending aortic aneurysm Descending aortic pseudo-aneurysm Contained aortic wall rupture ... Native or recurrent aortic coarctation*associated with ONE OR MORE of the following:. *Acute or chronic aortic wall injury, or ... Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta (COASTII). The ... Coarctation can occur in isolation, in association with bicuspid aortic valve or with major cardiac malformations. CoA accounts ...
... associated with balloon angioplasty for recurrent coarctation in neonatal univentricular and biventricular norwood-type aortic ... Recurrent coarctation following NTAR is more common in 2V patients than in SV patients. BA for recurrent coarctation has ... While many studies have evaluated recurrent coarctation following the NP, the incidence of recurrent coarctation and outcomes ... The incidence of recurrent coarctation requiring intervention was 19.3% in 2V vs. 9.7% in SV patients (P = 0.01) at a median of ...
ACQUIRED COARCTATION IN THE NEW CHANNEL OF A HEALED DISSECTING AORTIC ANEURYSM* DON E. SANDO, M.D.; STANDIFORD HELM, M.D., F.A. ... ANEURYSMAL DILATATION OF THE AORTIC SINUSES IN COARCTATION OF THE AORTA: REPORT OF TWO NEW CASES AND REVIEW OF THE LITERATURE*† ... SANDO DE, HELM S. ACQUIRED COARCTATION IN THE NEW CHANNEL OF A HEALED DISSECTING AORTIC ANEURYSM*. Ann Intern Med. 1952;37:793- ... Coarctation of the Aorta with Unusual Facies and Mental Retardation Annals of Internal Medicine; 69 (1): 103-106 ...
Number 10-18: Aortic Coarctation Repair with Associated Bicuspid Aortic Valve. Case from: Camastra GS, Cacciotti L, Sbarbati S ... Echocardiography revealed a bicuspid aortic valve with dilated aortic root and a coarctation of the descending thoracic aorta ... Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar;31(3):711-8.. 4. Puranik R, ... 2. Lam YY, Kaya MG, Li W, Mahadevan VS, Khan AA, Henein MY, Mullen M. Effect of endovascular stenting of aortic coarctation on ...
... we established a mid-thoracic aortic coarctation in the rabbit and studied gene expression and protein accumulation of these ... Differential Transmural Distribution of Gene Expression for Collagen Types I and III Proximal to Aortic Coarctation in the ... we established a mid-thoracic aortic coarctation in the rabbit and studied gene expression and protein accumulation of these ... collagen types proximal to the stenosis 1, 3 and 7 days and 2, 4 and 8 weeks after coarctation. The mRNA level of type I ...
Aortic coarctation and aortic stenosis are both forms of aortic narrowing. In terms of word root meanings, the names are not ... and recoarctation in elective aortic coarctation repair. Including long-term results after elective aortic coarctation repair ... The word "coarctation" means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with ... This spectrum is dichotomized by the idea that aortic coarctation occurs in the aortic arch, at or near the ductus arteriosis, ...
Coarctation of the aorta is a narrowing of the aorta most commonly found just distal to the origin of the left subclavian ... encoded search term (Aortic Coarctation) and Aortic Coarctation What to Read Next on Medscape. Related Conditions and Diseases ... The following surgical procedures have been performed to treat aortic coarctation:. * Resection of the coarctation site and end ... The prognosis for untreated aortic coarctation is poor. About 80% of untreated patients die of aortic dissection or rupture, ...
Diagnosis, imaging and clinical management of aortic coarctation Elles J Dijkema, Tim Leiner, Heynric B Grotenhuis ...
Aortic Coarctation-Adult. (Coarctation of the Aorta-Adult). by Krisha McCoy, MS ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... There are no current guidelines to prevent aortic coarctation because it is a congenital defect. ...
... Celal Yavuz,1 Hatice Ender Soydinc,2 Güven ... "Pregnancy Complicated with Severe Recurrent Aortic Coarctation: A Case Report," Case Reports in Vascular Medicine, vol. 2012, ...
Learn more about Aortic Coarctation -- Child at St. Davids HealthCare DefinitionCausesRisk ... Aortic coarctation (AC) is the narrowing of this artery. This slows or blocks blood flow. ... Effectiveness and safety of balloon dilation of native aortic coarctation in premature and neonates weighing , or = 2,500 grams ... Vijayalakshmi K, Griffiths A, Hasan A, OSullivan J. Late hazards after repair of coarctation of the aorta. BMJ. 2008;336(7647 ...
The suspicion of congenital postductal aortic coarctation was confirmed by transoesophageal echocardiography. Because of the ...
Re-coarctation or restenosis of the aorta following treatment is a... ... Purpose of Review Aortic coarctation is a common congenital abnormality causing significant morbidity and mortality if not ... Extraanatomic aortic bypass for repair of aortic arch coarctation via sternotomy: midterm clinical and magnetic resonance ... Risk factors for aortic complications in adults with coarctation of the aorta. J Am Coll Cardiol. 2004;44(8):1641-7.CrossRef ...
This corrective procedure is used to repair aortic coarctation, a narrowing of the aorta that impedes the flow of blood from ...
Aortic coarctation with secondary ruptured thoracic aortic aneurysm, active extravasation, hemothorax, and hemomediastinum. ... stroke and aortic dissection can also develop.2 This case seems unusual since today most people with aortic coarctation are ... Repair of coarctation-related aortic arch aneurysm and ventricular septal defect in an adolescent. Tex Heart Inst J. 2008;35(4 ... Historically, when aortic coarctation is untreated, the median age of death was 30 years. The leading causes of death included ...
... aortic coarctation explanation free. What is aortic coarctation? Meaning of aortic coarctation medical term. What does aortic ... Looking for online definition of aortic coarctation in the Medical Dictionary? ... Related to aortic coarctation: aortic stenosis. aortic coarctation. congenital narrowing of the aorta, usually located just ... aortic coarctation. Coarctation of aorta Cardiology A congenital heart defect which occurs in 7% of Pts with CHD; ♂ ♀ ratio, 2: ...
... were steps in correction of aortic coarctation with isthmus hypoplasia in nine patients aged 9-14 (mean ... Aortic Coarctation / surgery*. Blood Flow Velocity. Blood Pressure. Child. Electromagnetic Phenomena. Humans. Mammary Arteries ... Integration of IMA as a viable flap in the repair of aortic coarctation implies that this artery increases its collateral flow ... 1529299 - Flowmetric evaluation of internal mammary artery flap during repair of aortic coarctation.. 9033309 - Reoperative ...
Subtypes of bicuspid aortic valves in coarctation of the aorta. Rinnström, Daniel Umeå University, Faculty of Medicine, ... In coarctation of the aorta, BAVs are common, but the proportion of BAV subtypes and their relation to aortic dimensions and ... Coarctation of the aorta, Bicuspid aortic valves, Congenital heart disease, Cardiovascular magnetic resonance, Cardiovascular ... 24.2 ± 3.5 mm, p = 0.040) compared with tricuspid aortic valves (TAVs). Moderate and severe aortic valve disease was more ...
... disrupts aortic blood flow in a region and physiological manner akin to aortic coarctation in humans. Here we use a whole- ... Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation Nat Biotechnol. 2004 May;22(5):595-9. doi ... organism, phenotype-based, small-molecule screen to discover a class of compounds that suppress the coarctation phenotype and ...
... strain parameters were altered in repaired coarctation of the aorta (COA) with normal LV ejection fraction (EF) when compared ... regional myocardial deformation properties and increased aortic stiffness in normotensive patients with aortic coarctation ... Arterial hypertension and cardiovascular prognosis after successful repair of aortic coarctation: a clinical model for the ... Physiologic compensation is supranormal in compensated aortic stenosis: does it return to normal after aortic valve replacement ...
Congenital aortic stenosis (CAS) and Coarctation of Aorta (CoA) represent two forms of pressure afterload that affect the left ... The effect of pressure afterload due to aortic coarctation on left ventricular function in children. Jashari, Haki Umeå ... Congenital aortic stenosis, Coarctation of aorta, Left ventricle, Myocardial deformation imaging National Category Cardiac and ... Coarctation of the aorta, congenital aortic stenosis, left ventricle, myocardial deformation imaging, speckle tracking ...
Two clinical cases of patients suffering from aortic coarctations (CoA) were built and parameterized based on clinical data ... Two clinical cases of patients suffering from aortic coarctations (CoA) were built and parameterized based on clinical data ... Aortic valve. ,. mv ↔. Mitral valve. ,. lvbp ↔. Left ventricular bloodpool. ,. aobp ↔. Aortic bloodpool. .. (. 3. ). ... 2013). The impact of MRI-based inflow for the hemodynamic evaluation of aortic coarctation. Ann. Biomed. Eng. 41, 2575-2587. ...
We present a case report of rare association of right aortic arch with isolated left subclavian artery with coarctation of the ... Right aortic arch with isolated left subclavian artery: a rare association with coarctation of the left pulmonary artery ... We present a case report of rare association of right aortic arch with isolated left subclavian artery with coarctation of the ...
Stent placement is commonly used to treat aortic coarctation. Although invasive angiography remains the gold standard, follow- ... Complications After Stent Placement for Aortic Coarctation: A Pictorial Essay of Computed Tomographic Angiography. ... Furthermore, imaging findings of complications including aortic wall injuries, restenosis, and intimal hyperplasia are depicted ... types is shown along with reconstructions that can help assess stent integrity and the stent position in relation to the aortic ...
Stent Implantation for Adult Aortic Coarctation. Basil Vasilios Thanopoulos, Nicholaos Eleftherakis, Konstadinos Tzanos, ... Stent Implantation for Adult Aortic Coarctation Message Subject (Your Name) has forwarded a page to you from JACC: Journal of ... A) Aortogram showing a severe isolated native coarctation of the aorta (CoA) in a patient 30 years old with bicuspid aortic ... Stent Implantation for Adult Aortic Coarctation. Basil Vasilios Thanopoulos, Nicholaos Eleftherakis, Konstadinos Tzanos, ...
Aortic blood flow after coarctation repair with normal and hypoplastic aortic arch ... Aortic arch hypoplasia has been linked to aneurysm formation after coarctation repair, with abnormal blood flow proposed as a ... Arch Hypoplasia and Aneurysm After Aortic Coarctation Repair Message Subject (Your Name) has forwarded a page to you from JACC ... B) Identical analysis reveals a hypoplastic aortic arch (arrow) after coarctation repair resulting in eccentric flow and ...
  • Patients may present with aortic wall injury (aneurysm) related to prior CoA repair. (clinicaltrials.gov)
  • Hypertensive vascular complications, cerebrovascular hemorrhages, aortic aneurysm, aortic dissection or rupture, aortic valve deterioration, premature coronary disease are the most frequent life-threatening complications. (biomedcentral.com)
  • A large aortic knob with no other changes suggests a localized aneurysm or aortic dissection, especially if the patient is not elderly (Fig. 3). (myesr.org)
  • Enhanced coronal CT confirms an aneurysm of the aortic arch (B, arrow). (myesr.org)
  • A prominent left ventricular border often occurs with coarctation, particularly when a bicuspid aortic valve is associated with aortic stenosis. (medscape.com)
  • To assess the effects on the biosynthesis of collagen types I and III associated with an acute increase in blood pressure, we established a mid-thoracic aortic coarctation in the rabbit and studied gene expression and protein accumulation of these collagen types proximal to the stenosis 1, 3 and 7 days and 2, 4 and 8 weeks after coarctation. (ovid.com)
  • Aortic coarctation and aortic stenosis are both forms of aortic narrowing. (wikipedia.org)
  • This spectrum is dichotomized by the idea that aortic coarctation occurs in the aortic arch, at or near the ductus arteriosis, whereas aortic stenosis occurs in the aortic root, at or near the aortic valve. (wikipedia.org)
  • Some children born with coarctation of the aorta have other heart defects too, such as aortic stenosis, ventricular septal defect, patent ductus arteriosus or mitral valve abnormalities. (wikipedia.org)
  • Echocardiography showed severe AR within a normal tricuspid valve anatomy, aortic root dilatation (40 mm), left ventricle (LV) dysfunction (ejection fraction 40%) and, through a dorsal approach, a flow acceleration across a kinked segment of the descending aorta (maximum pressure gradient of 31 mmHg) with a post-stenosis mild ectasia (diameter of 38 mm) (Figure 1 ). (biomedcentral.com)
  • Owing to the suspicion of aortic coarctation, transthoracic echocardiography was performed, the aortic coarctation with dilation of the aorta proximal to the stenosis was confirmed and bicuspid aortic valve was found with good function. (biomedcentral.com)
  • Echocardiography supra sternal view shows aortic coarctation with dilation of the aortic segment proximal to the stenosis and acceleration of the flow. (biomedcentral.com)
  • Ventricular septal defect (VSD) and aortic stenosis were the most common associated lesions. (archivestsc.com)
  • Coarctation of the aorta may be associated with other heart defects like ventricular septal defect (VSD) and aortic stenosis. (childrenscolorado.org)
  • Coarctation of the aorta is a common congenital cardiovascular defect characterized by upper-body hypertension resulting from constriction of the aorta. (medscape.com)
  • Aortic coarctation is a congenital heart defect, which means it is present at birth. (stdavids.com)
  • Since aortic coarctation is a congenital defect, it cannot be prevented. (stdavids.com)
  • Coarctation of the aorta is a congenital malformation of the aorta in which part of the aorta is constricted or narrowed. (aarpmedicareplans.com)
  • Coarctation of the aorta (CoA) is a congenital malformation of the aorta. (aarpmedicareplans.com)
  • Coarctation of the aorta (CoA) is a congenital abnormality producing obstruction to blood flow through the aorta. (clinicaltrials.gov)
  • Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. (wikipedia.org)
  • Coarctation of the aorta (CoA) is a congenital malformation consisting in a narrowing of the aorta, usually located at the isthmus, and generating a pressure gradient between the aortic arch and the distal thoracic aorta. (biomedcentral.com)
  • Double orifice mitral valve is a rare congenital anomaly presenting as the division of the mitral orifice into two anatomically distinct orifices, it is most often associated with other congenital heart defects such as left-sided obstructive lesions, ventricular septal defects or aortic coarctation. (biomedcentral.com)
  • Coarctation of the aorta (COA) is a heart defect that is present at birth (congenital). (cedars-sinai.org)
  • Coarctation of the aorta in children is a congenital condition, meaning a child is born with it. (childrenscolorado.org)
  • However, a large aortic knob and descending aorta with a non-enlarged ascending aorta should raise the possibility of a type B aortic dissection (Fig. 2). (myesr.org)
  • Medial displacement of intimal calcium has been said to be a good sign of aortic dissection. (myesr.org)
  • We report the case of a 15 year's old boy, admitted for arterial hypertension, auscultation revealed a rude aortic systolic murmur. (biomedcentral.com)
  • A 15 year's old boy, admitted for arterial hypertension (BP: 160/90mmHg) , auscultation revealed a rude aortic systolic murmur. (biomedcentral.com)
  • associated anomalies of the mitral and aortic valve may also be demonstrated. (medscape.com)
  • Coarctation can occur in isolation, in association with bicuspid aortic valve or with major cardiac malformations. (clinicaltrials.gov)
  • Cardio-surgery consult indicated surgical repair of the aortic valve and no treatment for the CoA. (biomedcentral.com)
  • Echocardiography short axis parasternal view showed bicuspid aortic valve. (biomedcentral.com)
  • These include a bicuspid aortic valve. (cedars-sinai.org)
  • In some patients, coarctation can occur in conjunction with other left-sided heart lesions, in particular defects of the aortic or mitral valve. (wustl.edu)
  • For example, the association of bicuspid aortic valve and coarctation is common. (wustl.edu)
  • Time-resolved, 3D phase contrast magnetic resonance imaging (MRI) (4D Flow) was used to assess blood flow in the thoracic aorta of 34 individuals: 26 patients with coarctation (22 after surgery or stent placement) and eight healthy volunteers. (qxmd.com)
  • The upper arc of the 3 is the dilated arch proximal to the coarctation and/or a dilated left subclavian artery. (medscape.com)
  • citation needed] Play media There are three types of aortic coarctations: Preductal coarctation: The narrowing is proximal to the ductus arteriosus. (wikipedia.org)
  • Background: Controversy surrounds the optimal treatment for native coarctation of the aorta. (elsevier.com)
  • Outcomes associated with balloon angioplasty for recurrent coarctation in neonatal univentricular and biventricular norwood-type aortic arch recons. (nih.gov)
  • We evaluated the use of, and outcomes associated with, balloon angioplasty (BA) for recurrent coarctation in single ventricle (SV) and two ventricle (2V) patients following a Norwood-type aortic arch reconstruction (NTAR). (nih.gov)
  • Objectives: The purpose of this study was to compare the safety and efficacy of surgical, stent, and balloon angioplasty (BA) treatment of native coarctation acutely and at follow-up. (elsevier.com)
  • Five levels of severity have been defined for each of the 3 illness categories, including: Upper extremity hypertension, Upper to lower extremity pressure difference, and Severity of aortic wall injury. (clinicaltrials.gov)
  • 20 mmHg between upper and lower limbs or hypertension associated with a ≥ 50% narrowing relative to the reference aortic diameter (diaphragm level). (biomedcentral.com)
  • It has been estimated that 20 -30% of repaired aortic coarctation (CoA) patients develop hypertension, with significant cardiovascular morbidity and mortality. (medworm.com)
  • Prevalence of systemic hypertension, aortic stiffness, endothelial function, and left ventricular mass were similar among treatment groups. (elsevier.com)
  • Marked helical flow was seen in 9 of 13 patients with angulated aortic arch geometries after coarctation repair. (qxmd.com)
  • A small or non-existent left aortic knob in adults is usually because it is on the opposite side (right aortic arch). (myesr.org)
  • Angiography confirms the right aortic arch (B, white arrow). (myesr.org)
  • Unenhanced coronal CT shows that the mass corresponds to a right aortic arch (B, white arrow). (myesr.org)
  • The use of fabric-covered CP Stents to prevent or repair aortic wall injury has become the treatment of choice in Europe and recently in the US through the FDA Compassionate Use process. (clinicaltrials.gov)
  • COAST II will test safety and efficacy of Covered CP Stents to repair or prevent aortic wall injury associated with CoA. (clinicaltrials.gov)
  • Owing to the severity of the aortic coarctation and taking into account the anatomy and characteristics of the patient, he was made a surgical correction of aortic coarctation with good outcome. (biomedcentral.com)
  • What is coarctation of the aorta in children? (cedars-sinai.org)
  • Coarctation of the aorta in children is an abnormal narrowing of the aorta, which is the major artery that leaves the heart and delivers oxygenated blood to the rest of the body. (childrenscolorado.org)
  • Preductal coarctation results when an intracardiac anomaly during fetal life decreases blood flow through the left side of the heart, leading to hypoplastic development of the aorta. (wikipedia.org)
  • Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a somewhat hypoplastic arch to grow or from clamp injury at the time of the initial repair, or from both causes. (utmb.edu)
  • Measuring aortic diameter with different MR techniques: comparison of three-dimensional (3D) navigated steady-state free-precession (SSFP), 3D contrast-enhanced magnetic resonance angiography (CE-MRA), 2D T2 black blood, and 2D cine SSFP. (qxmd.com)
  • Clinical implication of parameter-optimized 3D-FISP MR angiography (MRA) in children with aortic coarctation: comparison with catheter angiography]. (qxmd.com)
  • We report the case of an elderly patient with history of congestive heart failure (CHF) and aortic regurgitation (AR) who was referred for progressive exertional dyspnoea. (biomedcentral.com)
  • No mitral or aortic regurgitation was documented by color Doppler flow imaging. (biomedcentral.com)
  • The diagnosis of coarctation of the aorta may be established from the posteroanterior (PA) chest image alone in up to 92% of patients. (medscape.com)
  • Background-Optimally treated patients with coarctation of the aorta remain at risk for late vascular dysfunction. (elsevier.com)
  • The LOVE-COARCT (Long-term Outcomes and Vascular Evaluation After Successful Coarctation of the Aorta Treatment) study was done to compare vascular function in patients with coarctation of the aorta treated with surgery, balloon dilation (BD), or stent implantation. (elsevier.com)
  • In patients with coarctation of the aorta, the body develops alternative pathways to get the blood beyond that area of narrowing. (wustl.edu)
  • The lower arc or bulge represents poststenotic dilatation of the aorta immediately below the coarctation. (medscape.com)
  • it is present in 75% of adults with coarctation. (medscape.com)
  • Most physicians who see older children or adults with aortic coarctation believe they had it very early on, but the degree of narrowing was not significant enough to cause problems, and it therefore missed detection. (wustl.edu)
  • Adults who have had longstanding coarctation can also develop aneurysms in their brains called "berry" aneurysms. (wustl.edu)
  • There are CoA patients with clinical situations that place them at high risk of aortic wall injury during bare metal stenting. (clinicaltrials.gov)
  • It is the result of obstruction of blood flow at the narrowed aortic segment, in conjunction with collateral blood flow through the intercostal arteries. (medscape.com)
  • Transsternal arch enlargement using cardiopulmonary bypass and moderate hypothermia without circulatory arrest is an attractive and safe approach for the treatment of arch obstruction after coarctation repair. (utmb.edu)
  • Unlike the use of extraanatomic bypass grafts, it allows complete relief of the obstruction, unhampered aortic growth, the minimal use of foreign material, and a repair that is protected deep within the mediastinal space. (utmb.edu)
  • Widening of the left subclavian artery border is the most common finding, but the most useful radiographic sign is an abnormal contour of the aortic arch, which may appear as a double bulge above and below the usual site of the aortic knob. (medscape.com)
  • 2) Abnormal aortic knob shadow from coarct and dilation of the left subclavian artery. (pedemmorsels.com)
  • Calcification of the aortic knob is normal in the elderly, but should be considered abnormal in young patients. (myesr.org)
  • When a patient has a coarctation, the left ventricle has to work harder. (wikipedia.org)
  • If the narrowing is severe enough, the left ventricle may not be strong enough to push blood through the coarctation, thus resulting in lack of blood to the lower half of the body. (wikipedia.org)
  • Pulsed and continuous-wave Doppler study may be used to determine the pressure gradient directly at the area of coarctation. (medscape.com)
  • Preoperative catheterization showed a 45-mmHg aortic pressure gradient and ventricular end-diastolic pressure of 11 mmHg. (elsevier.com)
  • To show that 4D Flow is a clinically viable tool for evaluation of collateral blood flow and demonstration of distorted blood flow patterns in patients with treated and untreated aortic coarctation. (qxmd.com)
  • Direct comparison of blood flow calculated with 2D and 4D phase contrast data at standard levels for analysis in coarctation patients showed good correlation and agreement (correlation coefficient r = 0.99, limits of agreement = -20% to 20% for collateral blood flow calculations). (qxmd.com)
  • 4D Flow is a fast and reliable means of evaluating collateral blood flow in patients with aortic coarctation in order to establish hemodynamic significance. (qxmd.com)
  • The standard approach for coarctation - particularly when identified in neonates and younger patients - is surgical. (wustl.edu)
  • Conclusions-In our cohort of patients without residual coarctation, treatment modality was not associated with major vascular outcomes, even though there were some favorable vascular characteristics in the BD patients. (elsevier.com)
  • LOVE-COARCT Study 2019, ' Impact of treatment modality on vascular function in coarctation of the aorta: The LOVE-COARCT study ', Journal of the American Heart Association , vol. 8, no. 7, e011536. (elsevier.com)
  • If coarctation is treated in later childhood or adolescence, it is less likely that high blood pressure can be resolved, even after the coarctation is treated, because of permanent changes that take place in the vascular system. (wustl.edu)
  • Cardiology agreed to perform ECHO, which demonstrated critical coarctation of the aorta. (pedemmorsels.com)
  • Flow-sensitive in-vivo 4D MR imaging at 3T for the analysis of aortic hemodynamics and derived vessel wall parameters]. (qxmd.com)