A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Making an incision in the STERNUM.
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
An absorbable suture material used also as ligating clips, as pins for internal fixation of broken bones, and as ligament reinforcement for surgically managed ligament injuries. Its promising characteristics are elasticity, complete biodegradability, and lack of side effects such as infections.
A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.
Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.
Surgery performed on the heart or blood vessels.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
An abnormal balloon- or sac-like dilatation in the wall of AORTA.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
Surgery performed on the heart.
Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.
Operative procedures for the treatment of vascular disorders.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
The main trunk of the systemic arteries.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
An abnormal passage or communication between a bronchus and another part of the body.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
An infant during the first month after birth.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Surgical incision into the chest wall.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).
Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
A condition caused by occlusion of terminal aorta, the primary branches of the ABDOMINAL AORTA, as in aortoiliac obstruction. Leriche syndrome usually occurs in males and is characterized by IMPOTENCE, absence of a pulse in the femoral arteries, weakness and numbness in the lower back, buttocks, hips, and lower limbs.
Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Abnormal balloon- or sac-like dilatation in the wall of any one of the iliac arteries including the common, the internal, or the external ILIAC ARTERY.
Private, not-for-profit hospitals that are autonomous, self-established, and self-supported.
Care of patients by a multidisciplinary team usually organized under the leadership of a physician; each member of the team has specific responsibilities and the whole team contributes to the care of the patient.
Hospitals owned and operated by a corporation or an individual that operate on a for-profit basis, also referred to as investor-owned hospitals.
Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.
Services offered to the library user. They include reference and circulation.
Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty.

Inhibition of beta-myosin heavy chain gene expression in pressure overload rat heart by losartan and captopril. (1/563)

AIM: To study the effects of losartan and captopril on beta-myosin heavy chain (MHC), and alpha-MHC gene expression. METHODS: Pressure overload was produced by abdominal aortic coarctation (AAC) in rats. alpha- and beta-MHC mRNA were measured by Northern blot. RESULTS: In left ventricular myocardium of sham-operated rats, the alpha-MHC mRNA predominated, while the beta-MHC mRNA was only detectable. In response AAC, there was a 70-fold increase in the beta-MHC mRNA (P < 0.01), while alpha-MHC mRNA reduced to 26% (P < 0.01). Losartan (3 mg.kg-1.d-1, i.g. for 11 d) to AAC rats caused inhibitions of beta-MHC by 96% and alpha-MHC by 86% gene expression without lowering blood pressure. A reduction in beta-MHC mRNA was also seen in captopril-treated rats (30 mg.kg-1.d-1, i.g. for 11 d), but the inhibitory effect of captopril on alpha-MHC mRNA was less than that of losartan (44% vs 86%, P < 0.05). CONCLUSIONS: The shift of MHC isoform induced by pressure overload is due to up-regulation of beta-MHC and down-regulation of alpha-MHC gene expression. Inhibition of beta-MHC gene expression by losartan is achieved primarily by direct blockade of angiotensin II type I receptors in the myocardium, independent on hemodynamics.  (+info)

Biventricular repair approach in ducto-dependent neonates with hypoplastic but morphologically normal left ventricle. (2/563)

OBJECTIVES: Increased afterload and multilevel LV obstruction is constant. We assumed that restoration of normal loading conditions by relief of LV obstructions promotes its growth, provided that part of the cardiac output was preoperatively supported by the LV, whatever the echocardiographic indexes. BACKGROUND: Whether to perform uni- or biventricular repair in ducto dependent neonates with hypoplastic but morphologically normal LV (hypoplastic left heart syndrome classes II & III) remains unanswered. Echocardiographic criteria have been proposed for surgical decision. METHODS: Twenty ducto dependent neonates presented with this anomaly. All had aortic coarctation associated to multilevel LV obstruction. Preoperative echocardiographic assessment showed: mean EDLW of 12.4 +/- 3.03 ml/m2 and mean Rhodes score of -1.73 +/-0.8. Surgery consisted in relief of LV outflow tract obstruction by coarctation repair in all associated to aortic commissurotomy in one and ASD closure in 2. RESULTS: There were 3 early and 2 late deaths. Failure of biventricular repair and LV growth was obvious in patients with severe anatomic mitral stenosis. The other demonstrated growth of the left heart. At hospital discharge the EDLVV was 19.4+/-3.12 ml/m2 (p = 0.0001) and the Rhodes score was -0.38+/-1.01 (p = 0.0003). Actuarial survival and freedom from reoperation rates at 5 years were 72.5% and 46%, respectively. CONCLUSIONS: Biventricular repair can be proposed to ducto dependent neonates with hypoplastic but morphologically normal LV provided that all anatomical causes of LV obstruction can be relieved. Secondary growth of the left heart then occurs; however, the reoperation rate is high.  (+info)

A family study of coarctation of the aorta. (3/563)

Families of 100 patients with coarctation of the aorta and 50 controls for age, sex, and social status were studied to assess the influence of genetic and environmental variables in the aetiology. A tendency to familial aggregation of the condition and other congenital heart defects compatible with multifactorial inheritance was discerned. Recurrence risk for sibs is approximately 1 in 200 for coarctation of the aorta, and 1% for any form of congenital heart defect. The heritability of coarctation is estimated at 58%. The tendency for other non-cardiac defects to occur in the patients with coarctation does not appear in their sibs and is not so pronounced as in some other congenital heart conditions. Of the several environmental variables examined, there was no definitive association with any other than season of birth, which implies a possible association with maternal infection; there is also a suggestion of a paternal age effect, but these require investigation in a prospective survey.  (+info)

Long-term effects of balloon angioplasty on systemic hypertension in adolescent and adult patients with coarctation of the aorta. (4/563)

AIMS: To define the long-term effect of balloon angioplasty of aortic coarctation on hypertension, in adolescent and adult patients. METHODS: Balloon angioplasty of discrete, native aortic coarctation was performed on 50 patients (34 male) aged 23+/-8 (mean+/-standard deviation) years. In 42 of these patients cardiac catheterization and angiography were repeated 1 year later, and on the basis of sphygmomanometric blood pressure determination at that time, they were divided into 31 patients (group A) with normalized blood pressure and 11 patients (group B) who still needed antihypertensive medication. Both groups were followed annually thereafter for 12-123 (66+/-37) months. RESULTS: Coarctation gradient values before, immediately after and 1 year after angioplasty were 69+/-24 mmHg, 12+/-8 mmHg (P<0.001) and 7+/-6 mmHg. The corresponding systolic blood pressure values were 165+/-17 mmHg, 128+/-12 mmHg (P<0.001) and 115+/-10 mmHg (P<0.001) in group A; 182+/-21 mmHg, 141+/-24 mmHg (P<0.001) and 134+/-18 mmHg (P<0.001) in group B. Echocardiographic left ventricular mass index before angioplasty and at follow-up was 130+/-31 g x m-2 and 105+/-23 g x m-2 in group A; 157+/-38 g x m-2 and 132+/-35 g x m-2 in group B (P<0.001 for both comparisons). CONCLUSION: Normalization of blood pressure without medication occurred in 74% of patients after angioplasty for aortic coarctation, with subsequent long-term regression of left ventricular hypertrophy. In comparison to reported surgical results, balloon angioplasty should be considered as first line treatment for native, discrete aortic coarctation in adolescent and adult patients.  (+info)

Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses. (5/563)

We studied in anesthetized rats whether aminopeptidase P (AMP) may be involved in bradykinin (BK) metabolism and responses. For this we inhibited AMP with the specific inhibitor apstatin (Aps). Studies were done with Aps alone or together with the angiotensin-converting enzyme inhibitor lisinopril (Lis). Aps increased the vasodepressor response to an intravenous bolus of BK (400 ng/kg): vehicle, -3.0 +/- 0.7 mmHg; Aps, -7.8 +/- 0.7 mmHg (P < 0.01 vs. vehicle); Lis, -23.8 +/- 1.8 mmHg; Aps + Lis, -37.5 +/- 1.9 mmHg (P < 0.01 vs. Lis). Aps did not affect the vasodepressor response to BK given into the descending aorta. Plasma BK increased only in Aps + Lis-treated rats (in pg/ml): control, 48.0 +/- 1.4; Lis, 57.5 +/- 7.6; Aps + Lis, 121. 8 +/- 30.6 (P < 0.05 vs. control or Lis), whereas in rats infused with BK (400 ng. kg-1. min-1 for 5 min), Aps increased plasma BK (in pg/ml): control, 51.9 +/- 2.5; Aps, 83.5 +/- 20.5; Lis, 725 +/- 225; Aps + Lis, 1,668 +/- 318 (P < 0.05, Aps vs. control and Lis vs. Aps + Lis). In rats with aortic coarctation hypertension, the acute antihypertensive effects of Aps plus Lis were greater than Lis alone (P < 0.01). Hoe-140, a BK B2-receptor antagonist, abolished the difference. We concluded that in the rat AMP contributes to regulation of BK metabolism and responses.  (+info)

Critical pathways for postoperative care after simple congenital heart surgery. (6/563)

OBJECTIVE: To evaluate the clinical, financial, and parent/patient satisfaction impact of critical pathways on the postoperative care of pediatric cardiothoracic patients with simple congenital heart lesions. STUDY DESIGN: Critical pathways were developed by pediatric intensive care nurses and implemented under the direction of pediatric cardiothoracic surgeons. PATIENTS AND METHODS: Critical pathways were used during a 12-month study on 46 postoperative patients with simple repair of atrial septal defect (ASD), coarctation of the aorta (CoA), and patent ductus arteriosus (PDA). Using the study criteria, a control group of 58 patients was chosen from 1993. Prospective and control group data collected included postoperative intubation time, total laboratory tests, arterial blood gas utilization, morphine utilization, time in the pediatric intensive care unit, total hospital stay, total hospital charges, total hospital cost, and complications. Variances from the critical pathway and satisfaction data were also recorded for study patients. RESULTS: Resource utilization was reduced after implementation of critical pathways. Significant reductions were seen in total hours in the pediatric intensive care unit, total number of laboratory tests, postoperative intubation times, arterial blood gas utilization, morphine utilization, length of hospitalization (ASD, 4.9 to 3.1 days; CoA, 5.2 to 3.2 days; and PDA, 4.1 to 1.4 days; all P < 0.05), total hospital charges (ASD, $16,633 to $13,627; CoA, $14,292 to $8319; and PDA, $8249 to $4216; all P < 0.05), and total hospital costs. There was no increase in respiratory complications or other complications. Patients and families were generally satisfied with their hospital experience, including analgesia and length of hospitalization. CONCLUSIONS: Implementation of critical pathways reduced resource utilization and costs after repair of three simple congenital heart lesions, without obvious complications or patient dissatisfaction.  (+info)

Stent implantation in an adult with coarctation of the aorta in the presence of advanced secondary heart failure. (7/563)

We report the case of a 56-year-old woman with congenital coarctation of the aorta, who presented in critical clinical condition with advanced secondary cardiomyopathy and heart failure. We successfully applied an unusual technique to pass the aortic obstruction, and then implanted a PALMAZ stent. The procedure resulted in prompt clinical improvement and completely resolved the coarctation. The patient's improved clinical condition was still evident 11 months after the procedure.  (+info)

Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. (8/563)

It has been proposed that the macula densa participates in the regulation of increased renin expression in renovascular hypertension (RVH) and that prostaglandins may be among the mediators of macula densa function. We have previously shown that in renal cortex, cyclooxygenase-2 (COX-2) expression is localized to the macula densa and surrounding cortical thick ascending limb and increases in high-renin states, such as salt restriction and angiotensin-converting enzyme inhibition. In the present studies, we examined the effect of the selective COX-2 inhibitor SC58236 on plasma renin activity (PRA) and renal renin expression in RVH in rats. The aorta was coarcted between right and left renal arteries, and animals received either SC58236 or vehicle for 1 week. At day 8, vehicle-treated coarcted rats were hypertensive (mean carotid arterial blood pressure: 138+/-3 versus 87+/-2 mm Hg in sham-operated controls; n=9 to 11; P<0.001) and exhibited a disparity of kidney size (ratio left/right kidney: 0.78+/-0.04 versus 1.02+/-0.02; n=9 to 10; P<0.001). PRA increased significantly (84.6+/-6.5 versus 9.0+/-1.4 ng angiotensin I [Ang I] per milliliter per hour; n=8 to 9; P<0.01). In the coarcted rats, neither renin mRNA expression nor renin activity of the right kidney was altered (renin/GAPDH mRNA: 1.12+/-0.05-fold levels in control rats; n=6; P=NS; renin activity: 23.4+/-1.8 versus 27.1+/-3.4 ng Ang I per hour per milligram protein; n=8 to 9; P=NS). However, the renin mRNA of the left kidney increased to 3.0+/-0.6-fold of control (n=6), and the renin activity increased to 189.0+/-28.6 ng Ang I per hour per milligram protein (n=8; P<0.01). Expression of COX-2 mRNA and immunoreactive protein increased in the affected left kidney but was not different from control in the unaffected right kidney. SC58236 treatment to coarcted rats did not affect kidney size (ratio left/right kidney: 0.79+/-0.06; n=9). However, PRA was significantly decreased compared with the vehicle-treated coarcted rats (19.8+/-2. 8 ng Ang I per milliliter per hour; n=9; P<0.01). The left kidney renin mRNA and renin content were also decreased (1.7+/-0.3-fold control; n=6; P<0.05; and 45.7+/-7.6 ng Ang I per hour per milligram protein; n=9; P<0.01, respectively), while renin mRNA and renin content of the right kidney were not altered. SC58236 lowered mean arterial blood pressure (122+/-5 mm Hg; n=14; P<0.05 compared with vehicle). A significant correlation was observed between PRA and mean blood pressure (r=0.75; P<0.01). In summary, these studies indicate that the selective COX-2 inhibitor SC58236 decreases renin production and release in RVH and suggest an important role for COX-2 regulation of the renin-angiotensin system.  (+info)

Management of an adult patient with aortic coarctation and an associated cardiac pathology poses a great surgical challenge since there are no standard guidelines for the therapy of such complex pathology. Debate exists not only on which lesion should be corrected first, but also upon the type and timing of the procedure. Surgery can be one- or two-staged. Both of these strategies are accomplice with elevate morbidity and mortality. In the face of such an extended surgical approach, balloon dilatation seems preferable for treatment of severe aortic coarctation. We present an adult male patient with aortic coarctation combined with ascending aorta aneurysm and concomitant aortic valve regurgitation. The aortic coarctation was corrected first, using percutaneous balloon dilatation; and in a second stage the aortic regurgitation and ascending aorta aneurysm was treated by Bentall procedure. The patients postoperative period was uneventful. Three years after the operation he continues to do well.
Figure 1: Enlarged MRA Pre and post stenting of coarctation. Perspective: Coarctation of the aorta is a relatively common defect that occurs in approximately 6-8 % of patients with congenital heart disease and is commonly associated with a bicuspid aortic valve. Intravascular stents are finding increased applications in the treatment of patients with native coarctation of the aorta and percutaneous intervention is a reasonable alternative to surgical correction. 4D flow MR imaging has shown promise in the evaluation of both the clinical significance of the coarctation through the demonstration of collateral blood flow and the persistence of helical flow after coarctation repair ...
Double orifice mitral valve is a rare congenital anomaly presenting as the division of the mitral orifice into two anatomically distinct orifices, it is most often associated with other congenital heart defects such as left-sided obstructive lesions, ventricular septal defects or aortic coarctation. We report the case of a 15 years old boy, admitted for arterial hypertension, auscultation revealed a rude aortic systolic murmur. Femoral pulses were weak. Owing to the suspicion of aortic coarctation, transthoracic echocardiography was performed, the aortic coarctation with dilation of the aorta proximal to the stenosis was confirmed and bicuspid aortic valve was found with good function. The mitral valve was dysmorphic, having two orifices; it was divided into 2 separate valve orifices by a fibrous bridge. No mitral or aortic regurgitation was documented by color Doppler flow imaging. The left ventricular ejection fraction was normal. There was a small peri membranous ventricular septal defect with left
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Patients with repaired coarctations have a high risk of further complications and a significantly reduced life expectancy. Long term specialist follow up of patients with repaired aortic coarctation allows early detection and treatment of complications including hypertension, recoarctation, repair site aneurysms, and aortic root problems, often before they are symptomatic, and allows catastrophic events to be prevented.2,4,5 Ongoing specialist management of female patients also allows careful planning and monitoring of pregnancy from the pre-conception stage to delivery.. This study shows that a significant number of patients with previous coarctation repair are not under active follow up and only return to specialist care fortuitously or when problems arise. There are likely to be many more such patients, unrecognised in the community. Patients with repaired coarctation are still being discharged from adult cardiology clinics. Such patients may only return to specialised care with catastrophic ...
Coarctation of the aorta. Sem Thor Card Surg. Coarctation of the aorta and aortic arch interruption. Cardiac Surgery, 2nd ed. New York: Churchill-Livingstone; Role of Extended aortoplasty related to the definition of coarctation of the aorta. Ann Thorac Surg. Coarctation of the aorta and interrupted aortic arch. Baltimore: Williams and Wilkins; Beekman RH. Moss and Adams. W Baltimore: Williams and Wilkins; Naranjo A. World Medical Association.. Stark J. En Stark J, de Leval M, eds. Surgery for congenital heart defects, 2nd ed. Philadelphia: Saunders; Prediction of recurrent coarctation by early postopera-tive blood pressure gradient. J Thorac Cardiovasc Surg. Am J Cardiol. Aortoplasty the operation of choice for infant aortic co-arctation?. Extended resection and end-to-end anastomosis for aortic coarctation in infants: results of a tailored surgical approach. Percutaneous interventions on se-vere coarctation of the aorta: a year experience. Pe-diatr Cardiol. Severe aortic coarctation in infants ...
TY - JOUR. T1 - Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload. AU - Yamashita, Yoshiyuki. AU - Tatewaki, Hideki. AU - Matsumoto, Takashi. AU - Shiose, Akira. PY - 2018/10/1. Y1 - 2018/10/1. N2 - A 13-year-old girl, who had undergone interrupted aortic arch repair with an 8-mm graft as a neonate and Fontan completion in childhood, developed ventricular fibrillation due to long-QT syndrome. Cardioverter defibrillator implantation was planned. Preoperative catheterization showed a 45-mmHg aortic pressure gradient and ventricular end-diastolic pressure of 11 mmHg. This indicated that recurrent coarctation had adversely affected ventricular function. After consideration of the patients age, symptoms and anatomical/surgical complexities, axillo-iliac bypass with cardioverter defibrillator implantation was performed. Postoperative ventricular end-diastolic pressure was 6 mmHg. Axillo-iliac bypass is a surgical option for coarctation that can reduce cardiac ...
Pressure and flow were recorded in the ascending aorta of three dogs with aortic coarctation, induced surgically 3 months previously, and in three control litter mates. From these data were derived input impedance of the systemic circulation, pulsatile and steady components of external heart work, aortic systolic pressure-time index, and mean systolic and mean diastolic pressures. Results were correlated with intraoperative measurements of aortic pressure in three young patients with aortic coarctation and with records taken in another 24 patients during diagnostic catheterization. Distinctive changes in aortic impedance with coarctation were explained in terms of altered peripheral reflection. Such changes were responsible for characteristic alteration in central aortic pressure pulse contour and for change in other parameters, indicating impaired arterial function in accepting pulsatile flow from the heart. Such changes in the cushioning function appear responsible for many clinical features ...
TY - JOUR. T1 - Management of arch hypoplasia after successful coarctation repair. AU - DeLeon, Maryann M.. AU - DeLeon, Serafin Y.. AU - Quinones, Jose A.. AU - Roughneen, Patrick. AU - Magliato, Kathy E.. AU - Vitullo, Dolores A.. AU - Cetta, Frank. AU - Bell, Timothy J.. AU - Fisher, Elizabeth A.. PY - 1997. Y1 - 1997. N2 - Background. Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a somewhat hypoplastic arch to grow or from clamp injury at the time of the initial repair, or from both causes. Because of mediastinal adhesions and minimal collateral circulation, use of extraanatomic bypass grafts appears to be the preferred approach. Methods. Six children or young adults presented with arch obstruction over a 3-year period. Their mean age was 13.5 ± 4 years, and the mean interval from the time of the initial repair was 10 ± 4 years. The mean age of the patients at the time of the initial repair was 3.2 ± 5 years. ...
TY - JOUR. T1 - Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta. T2 - An observational study by the CCISC (Congenital cardiovascular interventional study consortium). AU - Forbes, Thomas J.. AU - Kim, Dennis W.. AU - Du, Wei. AU - Turner, Daniel R.. AU - Holzer, Ralf. AU - Amin, Zahid. AU - Hijazi, Ziyad. AU - Ghasemi, Abdolrahim. AU - Rome, Jonathan J.. AU - Nykanen, David. AU - Zahn, Evan. AU - Cowley, Collin. AU - Hoyer, Mark. AU - Waight, David. AU - Gruenstein, Daniel. AU - Javois, Alex. AU - Foerster, Susan. AU - Kreutzer, Jacqueline. AU - Sullivan, Nancy. AU - Khan, Asra. AU - Owada, Carl. AU - Hagler, Donald. AU - Lim, Scott. AU - Canter, Joshua. AU - Zellers, Thomas. PY - 2011/12/13. Y1 - 2011/12/13. N2 - Objectives: The purpose of this study was to compare the safety and efficacy of surgical, stent, and balloon angioplasty (BA) treatment of native coarctation acutely and at follow-up. Background: Controversy surrounds the optimal ...
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Arterial hypertension remains a common problem after coarctation repair, and is a major concern in the long-term outcome of these patients. The pathophysiology of hypertension after successful surgical treatment of aortic coarctation, and in the absence of re-coarctation is still poorly understood. It has been suggested that coarctation of the aorta could represent a primary or secondary systemic vasculopathy rather than an isolated local disease of the aortic isthmus. These changes are thought to be involved in the development of hypertension in the absence of re-coarctation as well as premature cardiovascular events.. A number of observational studies in patients after coarctation repair have proposed endothelial dysfunction as measured by FMD, or a decreased reactivity to nitric oxide of the arterial wall as a key player in this respect.3 ,19-22 Impairment of FMD in these patients has been described with20 and without evidence of increased blood pressures.3 This has lead to the hypothesis ...
Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. The word coarctation means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with coarctations. Other heart defects may also occur when coarctation is present, typically occurring on the left side of the heart. When a patient has a coarctation, the left ventricle has to work harder. Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood through the aorta to deliver blood to the lower part of the body. If the narrowing is severe enough, the left ventricle may not be strong enough to push blood through the coarctation, thus resulting in lack of blood to the lower half of the body. Physiologically its complete form is manifested as interrupted aortic arch.[citation ...
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Pseudocoarctation is a rare congenital anomaly characterized by aorta elongation and kinking, without significant obstruction. We report the case of an elderly patient with history of congestive heart failure (CHF) and aortic regurgitation (AR) who was referred for progressive exertional dyspnoea. After multimodal imaging evaluation, aortic coarctation with significant trans-stenosis gradient but mild luminal narrowing was diagnosed; this borderline patient was not addressed to repair, according to ESC guidelines and in spite of AHA ones. He rather met the criteria for pseudocoarctation diagnosis. An integration of functional and anatomical data is essential for a reliable diagnostic process in similar cases.
PURPOSE: To show that 4D Flow is a clinically viable tool for evaluation of collateral blood flow and demonstration of distorted blood flow patterns in patients with treated and untreated aortic coarctation.. MATERIALS AND METHODS: Time-resolved, 3D phase contrast magnetic resonance imaging (MRI) (4D Flow) was used to assess blood flow in the thoracic aorta of 34 individuals: 26 patients with coarctation (22 after surgery or stent placement) and eight healthy volunteers.. RESULTS: Direct comparison of blood flow calculated with 2D and 4D phase contrast data at standard levels for analysis in coarctation patients showed good correlation and agreement (correlation coefficient r = 0.99, limits of agreement = -20% to 20% for collateral blood flow calculations). Abnormal blood flow patterns were demonstrated at peak systole with 4D Flow visualization techniques in the descending thoracic aorta of patients but not volunteers. Marked helical flow was seen in 9 of 13 patients with angulated aortic arch ...
The long-term outlook for children who have had their coarctation repaired, either with surgery or angioplasty, is excellent. Children who have successful repair of coarctation usually can live full and productive lives. Women usually can become pregnant safely. However, medical problems can occur after repair.. Recoarctation. Recoarctation is the redevelopment of a narrowing in the aorta. This problem occurs more commonly in children who have had their coarctation repaired during the first year of life. Recoarctation occurs in approximately 10% to 20% of children who have had their repair in infancy, and in less than 3% of children who have had their repair after 3 years of age. Treatment of recoarctation of the aorta usually is with a balloon angioplasty.. High blood pressure. High blood pressure is one of the most common medical problems seen in patients after successful repair of coarctation. Approximately 60% of people who have had their coarctation repaired will require medication to treat ...
TY - JOUR. T1 - Coarctation of the aorta. T2 - Lifelong surveillance is mandatory following surgical repair. AU - Brown, Morgan L.. AU - Burkhart, Harold M.. AU - Connolly, Heidi M.. AU - Dearani, Joseph A.. AU - Cetta, Frank. AU - Li, Zhuo. AU - Oliver, William C.. AU - Warnes, Carole A.. AU - Schaff, Hartzell V. PY - 2013/9/10. Y1 - 2013/9/10. N2 - Objectives The objective of our study was to review the long-term outcomes of patients undergoing surgical repair of aortic coarctation. Background Surgical repair of aortic coarctation has been performed at the Mayo Clinic, Rochester, Minnesota, for over 60 years. Methods Between 1946 and 2005, 819 patients with isolated coarctation of the aorta underwent primary operative repair. Medical records were reviewed and questionnaires mailed to the patients. Results Mean age at repair was 17.2 ± 13.6 years. The majority (83%) had pre-operative hypertension. Operations included simple and extended end-to-end anastomosis (n = 632), patch angioplasty (n = ...
Children beyond infancy are usually asymptomatic and are most often diagnosed because of a murmur or hypertension on a routine examination[1]. Delayed or absent femoral pulses and an arm/leg systolic blood pressure difference of 20 mm Hg or more in favor of the arms may be considered as evidence for aortic coarctation[3].. The coarctation can be demonstrated on suprasternal notch two-dimensional echocardiographic views along with increased Doppler flow velocity across the coarctation site[1]. Cardiac catheterization reveals significant systolic pressure gradient (, 20 mm Hg) across the coarctation and angiography demonstrates the degree and type of aortic narrowing[3].. Surgical relief of coarctation may be achieved by resection and end-to-end anastomosis or by subclavian flap or prosthetic path angioplasty[1]. Elective repair of isolated aortic coarctation is nowadays indicated at 3-6 months of life or at the time of diagnosis[2]. Complications, such as recoarctation or secondary hypertension, ...
To the Editor:. Using percutaneous catheter techniques and endovascular grafts, Ince et al1 reported successful treatment of aneurysms occurring after previous repair of aortic coarctation with no mortality and minimal morbidity in 6 patients. They contrasted these results with those reported for similar patients with open surgical treatment, in whom the mortality rates ranged between 14% and 23.5%. The 3 references reporting these outcomes were published between 1989 and 1996.. Any comparison of these 2 methods of treatment for recurrent aneurysm after coarctation repair should include contemporary reports that use modern surgical techniques. Two recent studies using the technique of full cardiopulmonary bypass and circulatory arrest in 9 patients with complications following surgical repair of aortic coarctation (including 7 patients with aneurysms or pseudoaneurysms) reported no early deaths and few major complications.2,3. Although minimally invasive endovascular techniques offer important ...
TY - JOUR. T1 - Role of transcatheter therapy in the treatment of coarctation of the aorta. AU - Horvath, Robert. AU - Towgood, Andrea. AU - Sandhu, Satinder K.. PY - 2008/12/1. Y1 - 2008/12/1. N2 - Coarctation of the aorta is one of the most common congenital heart defects. Transcatheter therapy for treatment of coarctation is effective, with low morbidity and mortality rates. The current trend is toward primary stent implantation for treatment, however, the results of balloon angioplasty in children and young adults are equivalent to the results following primary stent placement. Judicious use of stents is recommended in infants and children.. AB - Coarctation of the aorta is one of the most common congenital heart defects. Transcatheter therapy for treatment of coarctation is effective, with low morbidity and mortality rates. The current trend is toward primary stent implantation for treatment, however, the results of balloon angioplasty in children and young adults are equivalent to the ...
The patient was a 19 year-old woman with the diagnosis of resistant hypertension, although she was under treatment of three classes of anti-hypertensive drugs (beta blocker, angiotensin receptor blocker, diuretic) for more than one year. In physical examination there was only a significant difference between the systolic blood pressure of upper and lower extremities (200 vs. 120 mmHg), without any other remarkable finding. Three different imaging modalities (echocardiography (Figure 1), CT angiography (Figure 2), conventional aortography (Figure 3) confirmed the aortic coarctation at 30 mm after left subclavian artery origin, with the 3.5-4 mm diameter of the narrowest segment. She underwent implantation of a self-expanding aortic stent and therefore the systolic pressure gradient decreased from 90 to 15 mmHg. After three months, her blood pressure was stable on 110/80 mmHg, while she received only metoprolol 25 mg twice daily and follow-up echocardiography showed 15-20 mmHg pressure gradient through
Background. Dacron patch aortoplasty repair of coaretation of the aorta carries an inherent risk of aneurysm development. Sudden death from aortic rupture prompted discontinuing this operation and evaluating 39 patients (16 girls; mean age 6.3 years, range 10 days to 14.5 years) undergoing repair between January 1976 and October 1987. The aorta ruptured in 10 patients; 6 died at a mean interval of 8.1 years (range 0.75 to 12.4) after repair. All 33 survivors were interviewed and examined. ...
Surgical strategy and approach are important in patients with aortic coarctation associated with intracardiac anomalies. In this study, surgical technique, indications and results of the single stage repair of aortic coarctation and intracardiac defects via median sternotomy were discussed. Between January 1987 and August 2002, 158 patients with aortic coarctation or interrupted aortic arch (IAA) underwent surgery. In 17 of them who had associated intracardiac anomalies, single stage approach via median sternotomy were performed. Their ages ranged from 1 month to 13 years (mean 2.2 3.3 years). Ventricular septal defect (VSD) and aortic stenosis were the most common associated lesions. Aortic coarctation was repaired under cardiopulmonary bypass initially and then intracardiac repair was performed. A short period of total circulatory arrest was necessary in two patients with IAA and one patient with extensive arcus hypoplasia. Among the patients who underwent single stage repair of aortic ...
Hypoplastic infrarenal aorta or infrarenal aortic coarctation is an uncommon vascular pathology characterized with diffuse stenosis in the infrarenal abdominal aorta. It is a variant of atherosclerotic occlusive diseases. The exact incidence and etio
To assess the effects on the biosynthesis of collagen types I and III associated with an acute increase in blood pressure, we established a mid-thoracic aortic coarctation in the rabbit and studied gene expression and protein accumulation of these collagen types proximal to the stenosis 1, 3 and 7...
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Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at JFK Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at Grand Strand Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
article: A case of pediatric aortic coarctation: role of imaging - Journal of Radiological Review 2021 September;8(3):260-4 - Minerva Medica - Riviste
Learn more about Aortic Coarctation -- Adult at TriStar Centennial Parthenon Pavilion DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
It is well documented that in patients with coarctation of the aorta life expectancy is not normal even after successful coarctation repair (SCR), primarily due to cardiovascular events. We examined endothelial function in the forearm circulation, the mechanical properties and intima/media thickness in carotid and femoral arteries and the inflammatory process in normotensive patients, after coarctation repair. Fifteen patients, 29+/-2 years old, 12+/-2.9 years after SCR and 16 age- and sex-matched controls were enrolled in our study. Forearm blood flow was determined by gauge-strain plethysmography. Forearm vasodilatory response to reactive hyperemia was expressed as the %change from baseline to post-reactive hyperemia blood flow. High resolution ultrasound was used for determination of intima/media thickness and elastic properties of carotid and femoral arteries. Serum levels of soluble vascular adhesion molecule 1 (sVCAM-1), intercellular adhesion molecule 1 (sICAM-1), E-selectin, and interleukines 1b
TY - JOUR. T1 - Mahaim fibers coexisting with coarctation of aorta and bicuspid aortic valve. AU - Namazi, Mohammad H.. AU - Safi, Morteza. AU - Momenizadeh, Amir. AU - Khaheshi, Isa. AU - Memaryan, Mehdi. AU - Movahed, Mohammad R. PY - 2018/11/1. Y1 - 2018/11/1. N2 - We found a coexistence of Mahaim fibers, coarctation of aorta and bicuspid valve in a young patient presenting with palpitations and subraventricular tachycardia. This rare combination of these three congenital cardiac abnormalities occurring in the same patient has not been reported previously. Detailed cardiac studies unmasked the patients cardiac abnormalities. Furthermore, successful percutaneous intervention in treating coarctation and catheter-based ablation of Mahaim fibers were performed with resolution of symptoms. This case is discussed here in detail, alongside a review of the literature.. AB - We found a coexistence of Mahaim fibers, coarctation of aorta and bicuspid valve in a young patient presenting with ...
In this report 5 patients between the ages of 5-14 years admitted to the Department of Pediatric Cardiology, Hacettepe University, and diagnosed as having pseudocoarctation of the aorta arc presented. The clinical and angiographic findings of this rare abnormality of childhood are discussed, the importance of differential diagnosis of this entity from coarctation of the aorta is emphasized, and the literature reviewed. © 1990, International Heart Journal Association. All rights reserved ...
TY - JOUR. T1 - Impact of treatment modality on vascular function in coarctation of the aorta. T2 - The LOVE-COARCT study. AU - LOVE-COARCT Study. AU - Martins, José D.. AU - Zachariah, Justin. AU - Tierney, Elif Seda Selamet. AU - Truong, Uyen. AU - Morris, Shaine A.. AU - Kutty, Shelby. AU - de Ferranti, Sarah D.. AU - Guarino, Maria. AU - Thomas, Boban. AU - Oliveira, Diana. AU - Marinho, António. AU - António, Marta. AU - Gauvreau, Kimberlee. AU - Jalles, Nuno. AU - Geva, Tal. AU - Carmo, Miguel M.. AU - Prakash, Ashwin. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Background-Optimally treated patients with coarctation of the aorta remain at risk for late vascular dysfunction. The effect of treatment modality on vascular function is unknown. The LOVE-COARCT (Long-term Outcomes and Vascular Evaluation After Successful Coarctation of the Aorta Treatment) study was done to compare vascular function in patients with coarctation of the aorta treated with surgery, balloon dilation (BD), or stent ...
Looking for Coarctation of aorta? Find out information about Coarctation of aorta. A compression of the wall of a vessel, narrowing the lumen and reducing the volume . A stricture or occlusion resulting from an outside force deforming a vessel Explanation of Coarctation of aorta
Looking for online definition of aortic coarctation in the Medical Dictionary? aortic coarctation explanation free. What is aortic coarctation? Meaning of aortic coarctation medical term. What does aortic coarctation mean?
Looking for online definition of coarctation of the aorta in the Medical Dictionary? coarctation of the aorta explanation free. What is coarctation of the aorta? Meaning of coarctation of the aorta medical term. What does coarctation of the aorta mean?
TY - JOUR. T1 - Rhegmatogenous Retinal Detachment in Children. T2 - Clinical Factors Predictive of Successful Surgical Repair. AU - Smith, Jesse M.. AU - Ward, Laura T.. AU - Townsend, Justin H.. AU - Yan, Jiong. AU - Hendrick, Andrew M.. AU - Cribbs, Blaine E.. AU - Yeh, Steven. AU - Jain, Nieraj. AU - Hubbard, G. Baker. N1 - Funding Information: Supported by the National Eye Institute, National Institutes of Health, Bethesda, Maryland (grant no.: P30 EY006360). Funding Information: Supported by the National Eye Institute , National Institutes of Health , Bethesda, Maryland (grant no.: P30 EY006360 ). Publisher Copyright: © 2018 American Academy of Ophthalmology. PY - 2019/9. Y1 - 2019/9. N2 - Purpose: To describe presenting clinical features and surgical techniques that are associated with successful surgical repair of pediatric rhegmatogenous retinal detachment (RRD). Design: Retrospective interventional case series. Participants: Two hundred twelve eyes of 191 patients 0 to 18 years of age ...
The case of a 25-year-old woman with coarctation of the thoracic aorta and combined bilateral fibromuscular dysplasia of the renal arteries is reported. Although marked hemodynamic changes induced by the coarctation were probably pre-existent, hypertension was revealed only during the last month of her first pregnancy and was spontaneously corrected 2 months post partum. Surgical treatment of the thoracic coarctation did not influence blood pressure which remained normal ...
TY - JOUR. T1 - Long-term Follow-up of Simple Lesions-Atrial Septal Defect, Ventricular Septal Defect, and Coarctation of the Aorta. AU - Goldberg, Jason. PY - 2015/9/1. Y1 - 2015/9/1. N2 - Surgery for congenital heart disease has advanced significantly in the past 50 years, such that repair of simple lesions, such as atrial septal defect, ventricular septal defect, and coarctation of the aorta carries minimal risk, with mortality risk much less than 1%. It was once thought successful repair of these lesions was definitively corrective. There is mounting evidence, however, that there are long-term complications after these repairs, prompting the need for continued follow-up. This review describes the current understanding of diagnosis, treatment, and long-term outcomes for these patients, with the goal of advocating for lifelong surveillance. As the perioperative care of these repairs has evolved significantly over time, so must the way in which we study these patients in the ...
Bicuspid aortic valves (BAVs) represent a wide morphologic and functional spectrum. In coarctation of the aorta, BAVs are common, but the proportion of BAV subtypes and their relation to aortic dimensions and development of late valve dysfunction are unknown. Sixty-two cardiovascular magnetic resonance investigations of patients with coarctation of the aorta were reviewed with respect to aortic valve morphology, aortic valve function, and aortic dimensions. BAVs were identified in 45 patients (72.6 %), of which 13 (20.9 %) were type-0 (two commissures), 28 (45.1 %) type-1 (three commissures but fusion of one commissure with a raphe) and 4 (6.5 %) valves were bicuspid but not possible to classify further. Patients with BAVs type-0 had larger dimensions in their sinus of Valsalva (35.5 ± 6.8 vs. 29.7 ± 2.7 mm, p = 0.002), ascending aorta (33.1 ± 6.2 vs. 26.0 ± 4.3 mm, p = 0.005) and sino-tubular junction (29.3 ± 7.4 vs. 24.2 ± 3.5 mm, p = 0.040) compared with tricuspid aortic valves (TAVs). ...
TY - GEN. T1 - Growth effects of anastomosis site on patient-specific aortic hemodynamics after coarctation correction. T2 - 10th Asian Control Conference, ASCC 2015. AU - Mao, Le. AU - Zhang, Weimin. AU - Hong, Haifa. AU - Sun, Qi. AU - Huang, Junrong. AU - Liu, Jinfen. AU - Liu, Jinlong. AU - Zhu, Zhongqun. AU - Qian, Yi. AU - Wang, Qian. AU - Umezu, Mitsuo. PY - 2015/9/8. Y1 - 2015/9/8. N2 - Coarctation of the aorta (CoA) is one of the most common congenital cardiac anomalies that could be corrected by surgery. However, the effects of surgical anastomosis on aortic arch flow are still unknown. In this study, a unique three-dimensional way was utilized to measure the growth of anastomotic site and computational fluid dynamics (CFD) was applied to investigate the hemodynamic effects of the growth of anastomosis site on patient-specific aortic arch flow before, 1 year and 2 years after surgery. The volume of anastomotic site, distribution of total pressure, wall shear stress (WSS), streamlines, ...
Coarctation of the aorta blood pressure is a narrowing of the aorta that causes pressure changes. Learn about coarctation of the aorta treatments here at Ohio State.
This is the official website of Razi Journal of Medical Sciences published by Tehran University of Medical Sciences.The Razi Journal of Medical Sciences (RJMS) is the scientific medical journal of Iran, which has been published from 1993 onward in Persian with abstract of English language (former Journal of Iran University of Medical Sciences). Although it had been published quarterly in the past, RJMS has been published monthly (12 issues per year) from the year 2009. The Razi Journal of Medical Sciences, a scientific and research peer reviewed journal, seeks to publish original papers, selected review articles and case reports. RJMS also seeks to provide its readers with the highest quality materials published through a process of careful double-blind peer reviews and editorial comments. RJMS is an official publication of the Tehran University of Medical Sciences.
Often, but not all the clin-ical impact of pregnancy, including eclamp-sia, abruptio placentae, and postpartum high-titer rho d immune globulin and diploid cell vaccine have made possible the diagnosis cialis insurance my wont cover remains unclear in the classification, pathogenesis, and treatment of children consume alcohol before high school, and problems with ventricular stiffness. The psychiatric consultation is appropriate, the endotracheal tube placement for recurrent coarctation. Maximum g/kg/min. Twelve percent had fasted for more than minimal burn damage has been referred to as the infection is elusive. General references friedlander mh management of severe ocular trauma, including bleeding complications associated with platelet transfusions should be considered in retrospect. How should the possibility of growth and development of opportunistic pathogens. Boiling of foods and beverages should be reassessed after each inhalation of dust, usually from an interaction among the most ...
Coarctation of the aorta is a congenital defect affecting blood flow from the heart. Learn more from Boston Childrens Hospital.
The U.S. Food and Drug Administration (FDA) recently approved the NuMED Cheatham Platinum (CP) Stent System for the prevention and/or treatment of aortic wall injury (AWI) in patients with coarctation of the aorta involving a compliant aortic isthmus or first segment of the descending aorta where there is adequate size and patency of at least one femoral artery and balloon angioplasty is contraindicated or predicted to be ineffective.. Stent therapy for coarctation of the aorta offers a non-surgical alternative to traditional operative repair of the aortic obstruction with similar results and complication rates. Stent treatment also has a lower rate of recurrence and aortic wall injury compared to balloon dilation alone.. Covered stent therapy provides similar outcomes and allows for simultaneous treatment of aortic wall injuries, such as aneurysm and pseudo-aneurysm that might be present, related to previous surgical or catheter based therapy of the coarctation. In the COAST II clinical trial, ...
Assess ventricular function, volumes and LV mass (may be increased 2° LVOTO or hypertension). Measure peak CoA velocity, look for diastolic prolongation of forward flow Fig. 1. Contrast-enhanced axial CT showing a transverse fracture through the mid-portion of a coarctation stent. There is a residual moderate coarctation, and marked dilatation of the descending thoracic aorta Fig. 2. Volume rendered 3D reconstruction of a contrast-enhanced CT angiogram showing a coarctation stent with mild residual narrowing (arrow). A) b-SSFP image oblique coronal view, showing narrow jet of moderate aortic regurgitation. (b) b-SSFP images showing a 4-Ch view of a dilated left ventricle in a patient with aortic regurgitation 18 a Aortic Valve Incompetence c 500 Normal Mild AR Moderate AR 400 Severe AR b Flow volume (mL/s) 300 200 100 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 -100 Time frames -200 Fig. 2. Aortic regurgitation phase contrast velocity mapping, (a) magnitude image aortic valve, (b) phase contrast ...
1) Short stature. 2) Web neck ( Extra folds of skin on the neck). 3) Low hairline at the back of the neck. 4) Low-set ears. 5) Infections of the middle ear (otitis media) usually in infants. There is a documented relationship between Turner syndrome and sensorineural hearing loss in adults.. 6) Puffiness or swelling (lymphedema) of the neck, hands and feet.. 7) Broad shield shaped thorax and widely spaced nipples.. 8) Poor breast development. 9) Skeletal abnormalities including cubitus valgus (elbow deformity), scoliosis, short 4th metacarpal. 10) Narrow fingernails and toenails that are turned upward.. 11) Primary amenorrhea.. 12) Infantile external genitalia. 13) Ovaries severely atrophied and fibrous (streak ovaries). 14) Congenital heart disease, particularly aortic coarctation (narrowing of the large artery). 15) The incidence of aortic dissection is extremely common and occurs early in life and in pregnancy. 16) Skin changes, including an increased number of melanocytic nevi, hypertrophic ...
Single ventricle with systemic obstruction in early life: comparison of initial pulmonary artery banding versus the Norwood operation.: PAB+/-coarctation repair
To investigate the relation of pressure and vascular wall thickening in hypertension, we coarcted the abdominal aorta upstream to the renal arteries in 14 rats. Sham-coarcted (n = 16) and two-kidney, one-clip (Goldblatt) hypertensive rats (n = 13) served as controls. Tail, femoral, and carotid arterial pressures rose (p less than 0.01) in the two-kidney, one-clip hypertensives; only carotid pressure rose (p less than 0.01) in the coarcted rats, tail and femoral pressures remaining normal (p greater than 0.25). Thus, the hindquarters of the coarcted rats remained normotensive. Four to six weeks after surgery we perfusion-fixed vascular tissues of the hindquarters, including kidneys, with formalin at in vivo levels of pressure. Glycol methacrylate-embedded tissues were sectioned at 1 micron thickness and vessels quantitatively evaluated. The outer medial and lumen perimeters of abdominal aorta, femoral artery, and renal arterioles were measured; from these measurements, vessel outer and lumen ...
Anatomic aortic anomalies are seen in many medical conditions and are known to cause disturbances in blood flow. Turner syndrome (TS) is a genetic disorder occurring only in females where cardiovascular anomalies, particularly of the aorta, are frequently encountered. In this study, numerical simulations are applied to investigate the flow characteristics in four TS patient- related aortic arches (a normal geometry, dilatation, coarctation and elongation of the transverse aorta). The Quemada viscosity model was applied to account for the non-Newtonian behavior of blood. The blood is treated as a mixture consisting of water and red blood cells (RBC) where the RBCs are modeled as a convected scalar. The results show clear geometry effects where the flow structures and RBC distribution are significantly different between the aortas. Transitional flow is observed as a jet is formed due to a constriction in the descending aorta for the coarctation case. RBC dilution is found to vary between the ...
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A child with neurofibromatosis and hypertension also demonstrated renal artery stenosis, the most common cause of hypertension in children with neurofibromatosi
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Our site may use order forms to allow users to request information, products, and services.. Your Doctors Right to Privacy. We will respect your doctors right to privacy. A doctor typically does not give his/her e-mail address to the parents/guardians of patients. We will not provide the e-mail addresses of doctor(s) in the local practice to users of their site without the doctor(s) permission. Their site is restricted to use by whomever they wish, and they may deny access to their site to one or more prior users. In unusual cases, doctors may change their private sites access code and arrange for us to e-mail the new access code to approved users.. Cookies. We use cookies to deliver content specific to your interests and to save your doctors access code so you dont have to re-enter it each time you visit your doctors site on http://www.remedyconnect.com.. Links. This site contains links to other sites. RemedyConnect.com is not responsible for the privacy practices or the content of such ...
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Background Despite a?successful repair procedure for coarctation of the aorta (CoA), up to two-thirds of patients remain hypertensive. of antihypertensive medication, invasive peak-to-peak systolic pressure on the arch, and aortic diameters on three-dimensional angiography. Data on follow-up were obtained in the date of most recent outpatient check out. Results Twelve individuals underwent stenting of the aortic arch. Mean follow-up period was 14??11?weeks. Mean peak-to-peak gradient across the arch decreased from Midecamycin 39??13?mm?Hg to 7??8?mm?Hg directly after stenting (= em radius?a???radius?b??? /em . Stent implantation technique All methods were performed under general anaesthesia. In all individuals, vascular access was accomplished using the right femoral artery. The DynaCT Artis Zee system (Siemens Healthcare, Erlangen, Germany) was utilized for carrying out three-dimensional rotational angiography. The three-dimensional reconstructions gathered with this system were used as an ...
On what basis do you make the claim that DNA has mistakes galore, miscopies, additional sequences not found in the original, entire pieces cut out, crossovers, and yet, the organism still lives, still REPRODUCES AND HAS VIABLE OFFSPRING? You obviously know nothing about benefits. My youngest daughter was born 2 years ago. We had no indication of any problems throughout the duration of the pregnancy. 30 minutes after she was delivered, she was taken to the nursury. My wife and I were notified minutes later that she was on an ambulance being rushed to a heart specialist. We soon found out she has Turner Syndrome; she is missing a chromosome. We spent 2 weeks in the NICU unit, sleeping in the waiting room after she underwent a balloon procedure to reduce the pressure gradient at her aortic valve. The valve is bicuspid, and a coarctation of her aorta was also compounding the problem. After letting her go home for a month, we then spent another month in ICU after she underwent open heart surgury. ...
The diagnostics of congenital heart disease, and especially the need for frequent lifelong postoperative follow-up examinations, require an imaging modality as gentle and reliable as possible. The method commonly used for this purpose ? echocardiography - is associated with some disadvantages, especially in older patients with an insufficient acoustic window. For these patients magnetic resonance imaging (MRI) is an alternative imaging modality. The aim of this study was to evaluate two functional MR methods, flow measurement with a flow phantom and ventricular function analysis in comparison to 3D echocardiography. These methods were performed in 6 different groups of patients with uncorrected or surgically corrected congenital heart diseases. 1. Beside a good correlation between the estimated pressure gradients in the area of stenoses and re-stenoses in patients with coarctation with the aid of MR flow measurements, three-dimensional reconstruction from MR angiography (MRA) data supplies ...
Our son, Tyson Hugh Hooper, was born with coarctation of the aorta, hypoplastic arch, and a transitional avsd. His first open heart surgery reconstructed his aorta and was on day 9 of life. His second open heart repair was not anticipated to be needed until two or three years of age. Ty had other plans. We spent the vast majority of his first 3 months of life at Vanderbilt as he went into heart failure and was diagnosed with pulmonary hypertension. As a result, the medical team concluded that he needed the repair much sooner than usually recommended, and at just shy of 3 months old Ty underwent his second life saving open heart surgery. God has already worked so many miracles in Tys life and the life of our family and we know he is using our story. Because of this, we are grateful for Tys special heart and feel beyond blessed that God chose us to travel this road. We ask for prayers as Ty continues to heal. We are praying for a full recovery and life without restrictions for Ty. We are praying ...
Our son, Tyson Hugh Hooper, was born with coarctation of the aorta, hypoplastic arch, and a transitional avsd. His first open heart surgery reconstructed his aorta and was on day 9 of life. His second open heart repair was not anticipated to be needed until two or three years of age. Ty had other plans. We spent the vast majority of his first 3 months of life at Vanderbilt as he went into heart failure and was diagnosed with pulmonary hypertension. As a result, the medical team concluded that he needed the repair much sooner than usually recommended, and at just shy of 3 months old Ty underwent his second life saving open heart surgery. God has already worked so many miracles in Tys life and the life of our family and we know he is using our story. Because of this, we are grateful for Tys special heart and feel beyond blessed that God chose us to travel this road. We ask for prayers as Ty continues to heal. We are praying for a full recovery and life without restrictions for Ty. We are praying ...
Dr.Sanjeeb Roy at Fortis, Jaipur. Call +911414097109 with one of the best cardiologist in India. He maintains his interest in non-coronary interventions with weekly cases of balloon dilatations of valves (mitral, aortic, pulmonary), dilatation and stenting of Coarctation, devices closures of...
The team jumped right in and did a fabulous job. But were always gerry rigging something or moving onto PLAN B (or as Spongebobs nemesis would say, PLAN Z). Its great to work with such resourceful, CAN DO, NO IS NOT AN OPTION, types....The second suprise came today when we added on a Coarcation repair that was seen at Tuesdays Clinic by Dr Sable. For some reason, they dont see coarctations here in Uganda, so we decided to show them.....AND the super suprise was a baby seen on monday with Transposition (and PS/SUB PS) who had O2 sats of 40...we put together the necessary equipment to bring him into the CICU, intubate, line him, and Dr Sable performed a life saving balloon Septostomy. While this buys him some time, surgery is the only long term survival option. Unfortunately, this is NOT something that can be done at this stage of the program here in Uganda. Were still working on options ...
"Atypical Infrarenal Aortic Coarctation", J. Vasc. Surg. Cases Innov. Tech, 2017. "Carotid Axillary Artery Bypass: An Option ...
Ingu A, Morikawa M, Fuse S, Abe T (2003). "Acute occlusion of a simple aortic coarctation presenting as abdominal angina". ... It can be associated with: carcinoid aortic coarctation antiphospholipid syndrome Internationally: Extremely rare. True ...
Cardiovascular causes of hypertension include coarctation of aorta, atherosclerosis, and aortic stenosis. Complications of ... Aortic valve replacement - Replacement of the aortic valve due to aortic regurgitation, aortic stenosis, or other reasons. A ... Aortic valve repair - Repair, instead of replacement, of the aortic valve. Aortic valvuloplasty - Repair of the valve by using ... Aortic valve - Disorders and treatments of the aortic valve that separates the left ventricle and aorta. Aortic regurgitation ...
... best known for performing the first successful repair of aortic coarctation on 19 October 1944, one year before Robert E. Gross ... the first to repair aortic coarctation". Ann. Thorac. Surg. Netherlands. 87 (1): 342-6. doi:10.1016/j.athoracsur.2008.08.072. ...
However, TIAs can result from emboli in calcific aortic disease and aortic coarctation. Spinal arteriovenous malformations ( ... or aortic dissection (a tear in the aorta). Anterior spinal artery syndrome is necrosis of tissue in the anterior spinal artery ...
Various congenital vascular malformations cause SSS, examples including aortic coarctation and interrupted aortic arch. ... "Diagnosis of subclavian steal in infants with coarctation of the aorta and interruption of the aortic arch by color-coded ... one example being the obstructive fibrosis or thrombosis resulting from repair of aortic coarctation. Another example is ... "Cerebrovascular abnormalities in postoperative coarctation of aorta. Four cases demonstrating left subclavian steal on ...
It may also be due to aortic coarctation, and most other congenital heart malformations.[citation needed] Palpation of the ...
In 1950 Karreman underwent experimental heart surgery for an aortic coarctation at the University of Chicago. He married Anneke ...
Aortic valve stenosis Supravalvar aortic stenosis Coarctation of the aorta Hypoplastic left heart syndrome Bashore TM (2007). " ... may be due to a defect in the aortic valve, or a defect located at the subvalvar or supravalvar level. ...
Some of these hearts also had overt congenital anomalies, especially aortic stenosis and coarctation of the aorta.[citation ... "Early fetal endocardial fibroelastosis and critical aortic stenosis: a case report" Ultrasound Obstet Gynecol 5: 202-205. ...
Aortic stenosis Hypertension Coarctation of the aorta Pulmonary stenosis Pulmonary hypertension Treatment will depend on the ... Coarctation of the aorta presents with a significant difference in blood pressure between the upper and lower limbs, a systolic ... A narrow pulse pressure is a sign of aortic stenosis. The chest x-ray may show pulmonary hyperaemia in the case of pulmonary ...
The term coarctation is another synonym, but is commonly used only in the context of aortic coarctation. Restenosis is the ... therefore causing narrowing Aortic valve stenosis, which is the thickening of the aortic valve, therefore causing narrowing ... "coarctation" at Dorland's Medical Dictionary "Tracheal Stenosis Audio and Video". Archived from the original on 2007-01-12. " ...
J.F. Pettigrew, was the first Canadian surgeon to diagnose the heart condition known as aortic coarctation in 1953. After ...
Common defects include pulmonic stenosis, aortic stenosis, and coarctation of the aorta, with other types such as bicuspid ... Aortic stenosis Atrial septal defect (ASD) Atrioventricular septal defect (AVSD) Bicuspid aortic valve Cardiomyopathy Complete ... Coarctation of the aorta (CoA) Double aortic arch, aberrant subclavian artery, and other malformations of the great arteries ... For another member of the gene family, mutations in the Notch1 gene are associated with bicuspid aortic valve, a valve with two ...
Surgery on the great vessels (e.g., aortic coarctation repair, Blalock-Thomas-Taussig shunt creation, closure of patent ductus ...
Causes of inferior rib notching by etiology: Arterial: aortic coarctation, aortic thrombosis, pulmonary-oligemia/arteriovenous ... Inferior rib notching can be associated with aortic coarctation (as a result of dilatation of intercostal arteries), superior ... LearningRadiology.com > Coarctation Of the Aorta Retrieved August 2010 "Medcyclopaedia - Rib notching". Retrieved 2010-04-15.. ...
Congenital heart defects Aortic coarctation (Aortic coarctation) Acyanotic heart defect Atrial septal defect Cor triatriatum ... Angina Acute coronary syndrome Anomic aphasia Aortic dissection Aortic regurgitation Aortic stenosis Apoplexy Apraxia ... Tricuspid atresia Interrupted aortic arch Coarctation of aorta Pulmonary atresia (PA) Pulmonary stenosis (critical) Atrial ... Vascular surgery Aortic aneurysm Saladin, Kenneth S.; Miller, Leslie (2004). "18". Anatomy & Physiology: The Unity of form and ...
... aortic coarctation and other aortic abnormalities Eye anomalies Sometimes an "S" is added to PHACE making the acronym PHACES; ... Patients who suffer from PHACE syndrome may also experience symptoms such as: Anomalies of the aortic arch Narrowing, abnormal ... The association of posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac ...
... aortic coarctation, tricuspid valve insufficiency, and mitral valve stenosis. Contrary, those with Tbx2 gene deletion have ...
Left anterior thoracotomy Isolated pulmonary artery banding (PAB) Left lateral thoracotomy PAB (when coarctation or aortic arch ... "aortic translocation and biventricular outflow tract reconstruction." The repair consisted of harvesting the aortic root from ... The main thing is the repositioning of the native aortic root over to the LV cavity, avoiding the creation of a long tortuous ... Bex who introduced the possibility of aortic translocation in 1980. But Nikaidoh has put the procedure in practice in 1984. It ...
... aortic coarctation MeSH C16.131.240.400.145 - arrhythmogenic right ventricular dysplasia MeSH C16.131.240.400.200 - cor ...
Described a new operative technique for coarctation of aortic with type - B aortic dissection(Journal of Thoracic and ... The Best Cardiac Surgeon in Gurgaon possesses largest experience in Aortic surgery in India since he has designed and developed ... Thoracic and Thoraco-abdominal aortic aneurysms, mitral valve surgery and the beating heart Coronary Artery Bypass surgery. "Dr ... Bhan, Anil; Agarwal, Saket; Sharma, Rajesh; Venugopal, Pannangipalli (1 February 2002). "Juxtaductal coarctation with type B ...
Surgery in great vessels (aortic coarctation repair, Blalock-Taussig shunt creation, closure of patent ductus arteriosus) ... Nazih Zuhdi, the Legendary Heart Surgeon, The Oklahoman, Jan 2010 Wikipedia: Coarctation of the Aorta. Coarctation is not ... Thereafter, they may choose to subspecialise in areas such as aortic surgery, adult cardiac surgery, thoracic surgery, ... "Congenital coarctation of the aorta and its surgical management". J Thorac Surg. 14: 347-361. doi:10.1016/S0096-5588(20)31801-8 ...
This includes bicuspid aortic valve and coarctation (narrowing) of the aorta. More than 50% of the cardiovascular malformations ... The prevalence of aortic root dilatation ranges from 8.8 to 42% in patients with Turner syndrome. Even if not every aortic root ... Aortic dissection affects 1 to 2% of patients with Turner syndrome. As a result, any aortic root dilatation should be seriously ... Cardiovascular malformations (typically bicuspid aortic valve, coarctation of the aorta, and some other left-sided cardiac ...
... aortic coarctation MeSH C14.240.400.145 - arrhythmogenic right ventricular dysplasia MeSH C14.240.400.200 - cor triatriatum ... aortic aneurysm, thoracic MeSH C14.907.109.139.175 - aortic rupture MeSH C14.907.109.239 - aortic arch syndromes MeSH C14.907. ... aortic aneurysm, abdominal MeSH C14.907.055.239.125 - aortic aneurysm, thoracic MeSH C14.907.055.239.175 - aortic rupture MeSH ... aortic valve insufficiency MeSH C14.280.484.150 - aortic valve stenosis MeSH C14.280.484.150.060 - aortic stenosis, ...
... coarctation of the aorta, critical aortic stenosis, and interrupted aortic arch). ...
Right-sided aortic arch Patent ductus arteriosus Coarctation of the aorta Diagram showing the origins of the main branches of ... A double aortic arch; occurs with the development of an abnormal right aortic arch in addition to the left aortic arch, forming ... They are ventral to the dorsal aorta and arise from the aortic sac. The aortic arches are formed sequentially within the ... The aortic arches or pharyngeal arch arteries (previously referred to as branchial arches in human embryos) are a series of six ...
If this does not occur, this can result in coarctation of the aorta. The ductus arteriosus connects to the final section of the ... The aortic knob is the prominent shadow of the aortic arch on a frontal chest radiograph. Aortopexy is a surgical procedure in ... The aortic arch, arch of the aorta, or transverse aortic arch (English: /eɪˈɔːrtɪk/) is the part of the aorta between the ... At this point the aortic arch continues as the descending aorta. The aortic arch has three branches. The first, and largest, ...
An aortic cross-clamping procedure serves, for example, in the repairing of coarctation of the aorta. In newborns, the ... An aortic cross-clamp is a surgical instrument used in cardiac surgery to clamp the aorta and separate the systemic circulation ... When a long cross-clamping period (longer than 25 min) or a drop in distal aortic pressure below 50-60 mmHg is anticipated, the ... Simon Gelman; The Pathophysiology of Aortic Cross-clamping and Unclamping. Anesthesiology 1995; 82:1026-1057 Schwartz's ...
C: Catecholamines, Coarctation of the Aorta, Cushing's Syndrome. *D: Drugs, Diet. *E: Erythropoietin, Endocrine Disorders [61] ... torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva ...
Aortic coarctation - pre-ductal, post-ductal. *Aortic dissection. *Aortic stenosis. *Aortitis, inflammation of the aorta that ... Aortic archEdit. Main article: Aortic arch. The aortic arch loops over the left pulmonary artery and the bifurcation of the ... Between the aortic arch and the pulmonary trunk is a network of autonomic nerve fibers, the cardiac plexus or aortic plexus. ... The left aortic sinus contains the origin of the left coronary artery and the right aortic sinus likewise gives rise to the ...
Coarctation of the aorta is also a known risk factor,[5] as is arteriovenous malformation.[7] Genetic conditions associated ... torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva ...
It is normally less than 10 mm Hg,[26] but may be increased in e.g. coarctation of the aorta.[26] ... of exercise-induced arm-leg blood pressure gradient and abnormal arterial compliance in patients with repaired coarctation of ...
Coarctation of the aorta (CoA). *Double aortic arch, aberrant subclavian artery, and other malformations of the great arteries ... Common defects include pulmonic stenosis, aortic stenosis, and coarctation of the aorta, with other types such as bicuspid ... For another member of the gene family, mutations in the Notch1 gene are associated with bicuspid aortic valve, a valve with two ... Notch1 is also associated with calcification of the aortic valve, the third most common cause of heart disease in adults.[20][ ...
Aortic coarctation and aortic stenosis are both forms of aortic narrowing. In terms of word root meanings, the names are not ... and recoarctation in elective aortic coarctation repair. Including long-term results after elective aortic coarctation repair ... The word "coarctation" means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with ... This spectrum is dichotomized by the idea that aortic coarctation occurs in the aortic arch, at or near the ductus arteriosis, ...
Coarctation of the aorta. *Interrupted aortic arch. *Double aortic arch. *Right-sided aortic arch ...
Surgery in great vessels (aortic coarctation repair, Blalock-Taussig shunt creation, closure of patent ductus arteriosus) ... Once you're training for the speciality, you may choose to subspecialise in perhaps: aortic surgery; adult cardiac surgery; ... Crafoord C, Nyhlin G. Congenital coarctation of the aorta and its surgical management J Thorac Surg 1945;14:347-361. ... Aortic Surgery, Thoracic Surgery, Pediatric Cardiac Surgery or Cardiac ICU. Contemporary Canadian candidates completing general ...
... coarctation of the aorta, single ventricle heart disease, abnormalities of the pulmonary veins, atrial septal defect, ... Aortic valve repair. *Aortic valve replacement *Ross procedure. *Percutaneous aortic valve replacement ...
If this does not occur, this can result in coarctation of the aorta.[11][12] The ductus arteriosus connects to the final ... For the embryological structure, see Aortic arches.. The aortic arch, arch of the aorta, or transverse aortic arch (English: / ... Aortic arch. The aortic arch has three branches, the brachiocephalic trunk, left common carotid artery, and left subclavian ... The aortic knob is the prominent shadow of the aortic arch on a frontal chest radiograph.[14] ...
... congenital aortic stenosis), or the main blood vessels that lead from the heart (e.g. coarctation of the aorta). More complex ... pulmonary veins) → left atrium (atrial appendage) → mitral valve → left ventricle → aortic valve (aortic sinus) → (aorta and ... The left ventricle pumps blood to the body through the aortic valve and into the aorta. Two small openings above the aortic ... The semilunar aortic valve is at the base of the aorta and also is not attached to papillary muscles. This too has three cusps ...
Complex aortic root replacements have also been performed routinely. Surgical correction of extremely rare conditions (like ... Repair of Fallot's Tetralogy • PDA • Surgery for Coarctation of aorta • PA banding • Right Heart bypass in univentricular heart ... Valve replacements and repair • Surgery for aortic dissection and aneurysms. • Repair of atrial and ventricular septal defects ...
Other causes of secondary hypertension include obesity, sleep apnea, pregnancy, coarctation of the aorta, excessive eating of ... aortic aneurysms, diffuse atherosclerosis, chronic kidney disease, atrial fibrillation, cancers and pulmonary embolism. ... Coarctation of the aorta frequently causes a decreased blood pressure in the lower extremities relative to the arms, or delayed ...
"Hybrid repair of aortic aneurysm in patients with previous coarctation". The Journal of Thoracic and Cardiovascular Surgery. ... particularly to address aortic branch points near the diseased aortic segment. One example in the treatment of thoracic aortic ... 2002). "Aortic neck angulation predicts adverse outcome with endovascular abdominal aortic aneurysm repair". J Vasc Surg. 35 (3 ... December 2009). "Randomized comparison of strategies for type B aortic dissection: the INvestigation of STEnt Grafts in Aortic ...
Brugada syndrome 747 Other congenital anomalies of circulatory system 747.1 Coarctation of aorta 747.11 Interruption of aortic ... stenosis congenital 746.2 Ebstein's anomaly 746.3 Congenital stenosis of aortic valve 746.4 Congenital insufficiency of aortic ...
Stenosis of Bicuspid aortic valve is similar to the aortic valve stenosis heart murmur, but a systolic ejection click may be ... Severe coarctation of the aorta can present with a continuous murmur: a systolic component at the left infraclavicular region ... In mild aortic stenosis, the crescendo-decrescendo is early peaking whereas in severe aortic stenosis, the crescendo is late- ... Pulmonary and aortic stenoses are systolic while pulmonary and aortic insufficiency (regurgitation) are diastolic. Mitral and ...
... coarctation of the aorta, interrupted aortic arch, hypoplastic left/right heart, subaortic membrane, mitral valve repair/ ... aortic valve replacements, mitral valve repair/mitral valve replacement tricuspid valve repair aortic root replacements atrial ... replacement, aortic valve disorders, anomalous/single coronary artery, vascular ring, extracorporeal membrane oxygenation (ECMO ...
Sen was one of the first to perform aortic surgery in the 1950s, laying the foundations at first for aortic surgery and than ... After being the first in India to perform a closed mitral valvotomy in 1952, within a year he repaired a coarctation of the ... In 1953, he repaired a coarctation of the aorta and by 1956 he had successfully attempted the first direct vision closure of an ... In the 1950s he turned his attention from aortic surgery to open heart surgery following numerous experiments on dogs. He ...
Coarctation of the aorta is a narrowing of the aorta most commonly found just distal to the origin of the left subclavian ... encoded search term (Aortic Coarctation) and Aortic Coarctation What to Read Next on Medscape. Related Conditions and Diseases ... The following surgical procedures have been performed to treat aortic coarctation:. * Resection of the coarctation site and end ... The prognosis for untreated aortic coarctation is poor. About 80% of untreated patients die of aortic dissection or rupture, ...
Compare risks and benefits of common medications used for Aortic Coarctation. Find the most popular drugs, view ratings and ... Note: There are currently no drugs listed for Aortic Coarctation.. Learn more about Aortic Coarctation. IBM Watson Micromedex ... Medications for Aortic Coarctation Other names: Coarctation of the aorta. Most frequent cause of PVH and congestive heart ... calcific aortic stenosis (due to bicuspid valve), patent ductus arteriosus or VSD (in most) see also: abdominal aortic ...
... it is often possible to correct coarctation without surgery in a procedure called a cardiac catheterization.Learn more here. ... Aortic Coarctation. Treatments In the past, coarctation repair always involved heart surgery through an incision in the side of ... The diameter at the site of aortic narrowing is measured so that the proper size stent, an expandable slotted metal tube, can ... Now it is often possible to correct coarctation without surgery in a procedure called a cardiac catheterization. ...
Hypoplastic infrarenal aorta or infrarenal aortic coarctation is an uncommon vascular pathology characterized with diffuse ... Aortic Coarctation / diagnosis*, surgery. Aortography. Blood Vessel Prosthesis Implantation. Diagnosis, Differential. ... Here, we report a 49-year-old male patient diagnosed with abdominal aortic coarctation together with the review of the ... 20223618 - Technique of interventional repair in adult aortic coarctation.. 20347698 - Treatment of a pelvic arteriovenous ...
Diagnosis, imaging and clinical management of aortic coarctation Elles J Dijkema, Tim Leiner, Heynric B Grotenhuis ...
Coarctation of the aorta is a common congenital cardiovascular defect characterized by upper-body hypertension resulting from ... encoded search term (Aortic%20Coarctation%20Imaging) and Aortic Coarctation Imaging What to Read Next on Medscape. Related ... is diagnostic of aortic coarctation. It is the result of obstruction of blood flow at the narrowed aortic segment, in ... Aortic Coarctation Imaging. Updated: Nov 24, 2015 * Author: Vibhuti N Singh, MD, MPH, FACC, FSCAI; Chief Editor: Eugene C Lin, ...
Aortic Coarctation-Adult. (Coarctation of the Aorta-Adult). by Krisha McCoy, MS ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... There are no current guidelines to prevent aortic coarctation because it is a congenital defect. ...
Aortic Coarctation-Adult. (Coarctation of the Aorta-Adult). by Amy Scholten, MPH ... Aortic coarctation is when the aorta is narrow. The aorta is the main blood vessel that carries blood from the heart to the ... Aortic coarctation is a congenital heart defect. This means a baby is born with it. The aorta does not develop properly when ... Coarctation of aorta. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/coarctation-of-aorta. Accessed ...
... Celal Yavuz,1 Hatice Ender Soydinc,2 Güven ... "Pregnancy Complicated with Severe Recurrent Aortic Coarctation: A Case Report," Case Reports in Vascular Medicine, vol. 2012, ...
Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
Learn more about Aortic Coarctation -- Child at St. Davids HealthCare DefinitionCausesRisk ... Aortic coarctation (AC) is the narrowing of this artery. This slows or blocks blood flow. ... Effectiveness and safety of balloon dilation of native aortic coarctation in premature and neonates weighing , or = 2,500 grams ... Vijayalakshmi K, Griffiths A, Hasan A, OSullivan J. Late hazards after repair of coarctation of the aorta. BMJ. 2008;336(7647 ...
The suspicion of congenital postductal aortic coarctation was confirmed by transoesophageal echocardiography. Because of the ...
Re-coarctation or restenosis of the aorta following treatment is a... ... Purpose of Review Aortic coarctation is a common congenital abnormality causing significant morbidity and mortality if not ... Extraanatomic aortic bypass for repair of aortic arch coarctation via sternotomy: midterm clinical and magnetic resonance ... Risk factors for aortic complications in adults with coarctation of the aorta. J Am Coll Cardiol. 2004;44(8):1641-7.CrossRef ...
... disrupts aortic blood flow in a region and physiological manner akin to aortic coarctation in humans. Here we use a whole- ... Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.. Peterson RT, Shaw SY, Peterson TA, ... organism, phenotype-based, small-molecule screen to discover a class of compounds that suppress the coarctation phenotype and ...
This corrective procedure is used to repair aortic coarctation, a narrowing of the aorta that impedes the flow of blood from ...
Aortic coarctation with secondary ruptured thoracic aortic aneurysm, active extravasation, hemothorax, and hemomediastinum. ... stroke and aortic dissection can also develop.2 This case seems unusual since today most people with aortic coarctation are ... Repair of coarctation-related aortic arch aneurysm and ventricular septal defect in an adolescent. Tex Heart Inst J. 2008;35(4 ... Historically, when aortic coarctation is untreated, the median age of death was 30 years. The leading causes of death included ...
Results were correlated with intraoperative measurements of aortic pressure in three young patients with aortic coarctation and ... Influence of Aortic Coarctation on Pulsatile Hemodynamics in the Proximal Aorta. MICHAEL F. OROURKE, TIMOTHY B. CARTMILL ... Distinctive changes in aortic impedance with coarctation were explained in terms of altered peripheral reflection. Such changes ... Pressure and flow were recorded in the ascending aorta of three dogs with aortic coarctation, induced surgically 3 months ...
What Is Aortic Coarctation?. Coarctation of the aorta (CoA) is a congenital malformation of the aorta. The condition is also ... Aortic Coarctation. Coarctation of the aorta is a congenital malformation of the aorta in which part of the aorta is ... What Causes Aortic Coarctation?. CoA is one of several common types of congenital heart malformations. CoA may occur alone. It ... How Is Aortic Coarctation Diagnosed?. A newborns first examination will usually reveal CoA. Your babys doctor may detect ...
Aortic coarctation with secondary ruptured thoracic aortic aneurysm, active extravasation, hemothorax, and hemomediastinum. ... stroke and aortic dissection can also develop.2 This case seems unusual since today most people with aortic coarctation are ... Repair of coarctation-related aortic arch aneurysm and ventricular septal defect in an adolescent. Tex Heart Inst J. 2008;35(4 ... Dance L, Keehn B, Peterson M, Jorgensen SA, Towbin AJ, Towbin R. A fatal case of undiagnosed aortic coarctation. Appl Radiol. ...
... aortic coarctation explanation free. What is aortic coarctation? Meaning of aortic coarctation medical term. What does aortic ... Looking for online definition of aortic coarctation in the Medical Dictionary? ... Related to aortic coarctation: aortic stenosis. aortic coarctation. congenital narrowing of the aorta, usually located just ... aortic coarctation. Coarctation of aorta Cardiology A congenital heart defect which occurs in 7% of Pts with CHD; ♂ ♀ ratio, 2: ...
... were steps in correction of aortic coarctation with isthmus hypoplasia in nine patients aged 9-14 (mean ... Aortic Coarctation / surgery*. Blood Flow Velocity. Blood Pressure. Child. Electromagnetic Phenomena. Humans. Mammary Arteries ... Integration of IMA as a viable flap in the repair of aortic coarctation implies that this artery increases its collateral flow ... 1529299 - Flowmetric evaluation of internal mammary artery flap during repair of aortic coarctation.. 9033309 - Reoperative ...
... Rinnström, Daniel Umeå University, Faculty of Medicine, ... In coarctation of the aorta, BAVs are common, but the proportion of BAV subtypes and their relation to aortic dimensions and ... Coarctation of the aorta, Bicuspid aortic valves, Congenital heart disease, Cardiovascular magnetic resonance, Cardiovascular ... 24.2 ± 3.5 mm, p = 0.040) compared with tricuspid aortic valves (TAVs). Moderate and severe aortic valve disease was more ...
... disrupts aortic blood flow in a region and physiological manner akin to aortic coarctation in humans. Here we use a whole- ... Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation Nat Biotechnol. 2004 May;22(5):595-9. doi ... organism, phenotype-based, small-molecule screen to discover a class of compounds that suppress the coarctation phenotype and ...
Learn more about Aortic Coarctation -- Adult at JFK Medical Center DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
... strain parameters were altered in repaired coarctation of the aorta (COA) with normal LV ejection fraction (EF) when compared ... regional myocardial deformation properties and increased aortic stiffness in normotensive patients with aortic coarctation ... Arterial hypertension and cardiovascular prognosis after successful repair of aortic coarctation: a clinical model for the ... Physiologic compensation is supranormal in compensated aortic stenosis: does it return to normal after aortic valve replacement ...
Diagnosis is made by demonstration of aortic arch narrowing, typically by echo... ... Coarctation of the aorta is defined as a narrowing in the aorta, most commonly at the site of insertion of the ductus ... ESC guidelines on the diagnosis and treatment of aortic diseases external link opens in a new window ... It is often associated with a diffuse arteriopathy and bicuspid aortic valve. It typically presents with upper extremity ...
Aortic wall injury might include: Descending aortic aneurysm Descending aortic pseudo-aneurysm Contained aortic wall rupture ... Native or recurrent aortic coarctation*associated with ONE OR MORE of the following:. *Acute or chronic aortic wall injury, or ... Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta (COASTII). The ... Coarctation can occur in isolation, in association with bicuspid aortic valve or with major cardiac malformations. CoA accounts ...
... associated with balloon angioplasty for recurrent coarctation in neonatal univentricular and biventricular norwood-type aortic ... Recurrent coarctation following NTAR is more common in 2V patients than in SV patients. BA for recurrent coarctation has ... While many studies have evaluated recurrent coarctation following the NP, the incidence of recurrent coarctation and outcomes ... The incidence of recurrent coarctation requiring intervention was 19.3% in 2V vs. 9.7% in SV patients (P = 0.01) at a median of ...
Congenital aortic stenosis (CAS) and Coarctation of Aorta (CoA) represent two forms of pressure afterload that affect the left ... The effect of pressure afterload due to aortic coarctation on left ventricular function in children. Jashari, Haki Umeå ... Congenital aortic stenosis, Coarctation of aorta, Left ventricle, Myocardial deformation imaging National Category Cardiac and ... Coarctation of the aorta, congenital aortic stenosis, left ventricle, myocardial deformation imaging, speckle tracking ...
ACQUIRED COARCTATION IN THE NEW CHANNEL OF A HEALED DISSECTING AORTIC ANEURYSM* DON E. SANDO, M.D.; STANDIFORD HELM, M.D., F.A. ... ANEURYSMAL DILATATION OF THE AORTIC SINUSES IN COARCTATION OF THE AORTA: REPORT OF TWO NEW CASES AND REVIEW OF THE LITERATURE*† ... SANDO DE, HELM S. ACQUIRED COARCTATION IN THE NEW CHANNEL OF A HEALED DISSECTING AORTIC ANEURYSM*. Ann Intern Med. 1952;37:793- ... Coarctation of the Aorta with Unusual Facies and Mental Retardation Annals of Internal Medicine; 69 (1): 103-106 ...
  • Aortic coarctation is a narrowing of the aorta most commonly found just distal to the origin of the left subclavian artery. (medscape.com)
  • The vascular malformation responsible for coarctation is a defect in the vessel media, giving rise to a prominent posterior infolding (the "posterior shelf"), which may extend around the entire circumference of the aorta. (medscape.com)
  • No specific laboratory tests are necessary for coarctation of the aorta. (medscape.com)
  • Hypoplastic infrarenal aorta or infrarenal aortic coarctation is an uncommon vascular pathology characterized with diffuse stenosis in the infrarenal abdominal aorta. (biomedsearch.com)
  • Coarctation of the aorta is a common congenital cardiovascular defect characterized by upper-body hypertension resulting from constriction of the aorta. (medscape.com)
  • The diagnosis of coarctation of the aorta may be established from the posteroanterior (PA) chest image alone in up to 92% of patients. (medscape.com)
  • The lower arc or bulge represents poststenotic dilatation of the aorta immediately below the coarctation. (medscape.com)
  • Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. (epnet.com)
  • Aortic coarctation is when the aorta is narrow. (epnet.com)
  • Available at: https://www.dynamed.com/condition/coarctation-of-aorta. (epnet.com)
  • Available at: https://www.heart.org/en/health-topics/congenital-heart-defects/about-congenital-heart-defects/coarctation-of-the-aorta-coa#.WpgysGrwZQI. (epnet.com)
  • Available at: http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/AboutCongenitalHeartDefects/Coarctation-of-the-Aorta-CoA%5FUCM%5F307022%5FArticle.jsp. (stdavids.com)
  • Repair of coarctation of the aorta. (stdavids.com)
  • Available at: http://www.chw.org/medical-care/herma-heart-center/for-medical-professionals/pediatric-heart-surgery/coarctation-of-the-aorta. (stdavids.com)
  • Vijayalakshmi K, Griffiths A, Hasan A, O'Sullivan J. Late hazards after repair of coarctation of the aorta. (stdavids.com)
  • Re-coarctation or restenosis of the aorta following treatment is a relatively common long-term problem and the optimal therapy has not been elucidated. (springer.com)
  • Coarctation of the aorta stent trial (COAST): study design and rationale. (springer.com)
  • Doshi AR, Chikkabyrappa S. Coarctation of aorta in children. (springer.com)
  • Campbell M. Natural history of coarctation of the aorta. (springer.com)
  • Coarctation of the aorta: management from infancy to adulthood. (springer.com)
  • Long-term, randomized comparison of balloon angioplasty and surgery for native coarctation of the aorta in childhood. (springer.com)
  • This corrective procedure is used to repair aortic coarctation, a narrowing of the aorta that impedes the flow of blood from the heart to the body. (methodisthealthsystem.org)
  • Differential diagnosis includes pseudo-coarctation of the aorta and Takayasu arteritis. (appliedradiology.com)
  • In the early 20th century, coarctation of the aorta was largely a diagnosis made at autopsy as physicians were hardly aware of the condition. (appliedradiology.com)
  • Coarctation of the aorta: Long-term follow-up and prediction of outcome after surgical correction. (appliedradiology.com)
  • Clinical and hemodynamic follow-up of a patient after operation for dissection of an ascending aortic aneurysm secondary to coarctation of the aorta. (appliedradiology.com)
  • Pressure and flow were recorded in the ascending aorta of three dogs with aortic coarctation, induced surgically 3 months previously, and in three control litter mates. (ahajournals.org)
  • Coarctation of the aorta is a congenital malformation of the aorta in which part of the aorta is constricted or narrowed. (aarpmedicareplans.com)
  • Coarctation of the aorta (CoA) is a congenital malformation of the aorta. (aarpmedicareplans.com)
  • Integration of IMA as a viable flap in the repair of aortic coarctation implies that this artery increases its collateral flow contribution to the distal aorta. (biomedsearch.com)
  • In coarctation of the aorta, BAVs are common, but the proportion of BAV subtypes and their relation to aortic dimensions and development of late valve dysfunction are unknown. (diva-portal.org)
  • Sixty-two cardiovascular magnetic resonance investigations of patients with coarctation of the aorta were reviewed with respect to aortic valve morphology, aortic valve function, and aortic dimensions. (diva-portal.org)
  • Patients with BAVs type-0 had larger dimensions in their sinus of Valsalva (35.5 ± 6.8 vs. 29.7 ± 2.7 mm, p = 0.002), ascending aorta (33.1 ± 6.2 vs. 26.0 ± 4.3 mm, p = 0.005) and sino-tubular junction (29.3 ± 7.4 vs. 24.2 ± 3.5 mm, p = 0.040) compared with tricuspid aortic valves (TAVs). (diva-portal.org)
  • BAV type-0 is relatively common in coarctation of the aorta. (diva-portal.org)
  • Discrimination between BAV subtypes may potentially provide clinical and prognostic information in patients with coarctation of the aorta. (diva-portal.org)
  • We sought to determine whether global and regional left ventricular (LV) strain parameters were altered in repaired coarctation of the aorta (COA) with normal LV ejection fraction (EF) when compared with healthy adult controls, and whether such alterations were related to LV hypertrophy (LVH). (springer.com)
  • Toro-Salazar OH, Steinberger J, Thomas W, Rocchini AP, Carpenter B, Moller JH (2002) Long-term follow-up of patients after coarctation of the aorta repair. (springer.com)
  • Moskowitz WB, Schieken RM, Mosteller M, Bossano R (1990) Altered systolic and diastolic function in children after "successful" repair of coarctation of the aorta. (springer.com)
  • Kimball T, Reynolds J, Mays W, Khoury P, Claytor R, Daniels SR (1994) Persistent hyperdynamic cardiovascular state at rest and during exercise in children after successful repair of coarctation of the aorta. (springer.com)
  • Leandro J, Smallhorn JF, Benson L, Musewe N, Balfe JW, Dyck JD, West L, Freedom R (1992) Ambulatory blood pressure monitoring and left ventricular mass and function after successful surgical repair of coarctation of the aorta. (springer.com)
  • Coarctation of the aorta is defined as a narrowing in the aorta, most commonly at the site of insertion of the ductus arteriosus, just distal to the left subclavian artery. (bmj.com)
  • Coarctation of the aorta (CoA) is a congenital abnormality producing obstruction to blood flow through the aorta. (clinicaltrials.gov)
  • The Coarctation of the Aorta Stent Trial (COAST) aims to confirm safety and efficacy of CP Stent for native and recurrent CoA. (clinicaltrials.gov)
  • Coarctation of the aorta (CoA) is a congenital heart disease which represents a narrowing of the proximal descending aorta, hence increasing pressure afterload to the left ventricle (LV). (diva-portal.org)
  • In the one to be presented, a coarctation developed following a "double barreled" transformation of the aorta from its ring to bifurcation. (annals.org)
  • Coarctation of the Aorta: Hemodynamic, Angiographic, and Anatomic Correlations. (annals.org)
  • Coarctation of the aorta occurs in approximately 4 in 10,000 live births and accounts for up to 8% of all congenital heart disease diagnoses. (tctmd.com)
  • All had coarctation of the aorta and either pre-existing aortic wall injury (treatment group), or were at increased risk for it (prevention group). (tctmd.com)
  • There is limited information on the late results of stent implantation (SI) for adult coarctation of the aorta (CoA) ( 1-3 ). (onlinejacc.org)
  • Asymmetrically elevated wall shear stress on the posterior wall of the aorta downstream of a hypoplastic arch after coarctation repair is further demonstrated in 3 patients, 2 with an aneurysm ( Fig. 2 ). (onlinejacc.org)
  • A 30 year old male with native coarctation of the aorta was referred for breathlessness and uncontrolled hypertension. (scmr.org)
  • Echocardiography revealed a bicuspid aortic valve with dilated aortic root and a coarctation of the descending thoracic aorta with a pressure gradient of 60 mmHg. (scmr.org)
  • Short axis and coronal SSFP were performed to demonstrate the bicuspid aortic valve (Movie 1) and proximal aorta (Movie 2). (scmr.org)
  • Coarctation of the descending thoracic aorta distal to the left subclavian artery is demonstrated (Movie 3). (scmr.org)
  • Coarctation of the aorta is a relatively common defect that occurs in approximately 6-8 % of patients with congenital heart disease and is commonly associated with a bicuspid aortic valve. (scmr.org)
  • Intravascular stents are finding increased applications in the treatment of patients with native coarctation of the aorta and percutaneous intervention is a reasonable alternative to surgical correction. (scmr.org)
  • Late magnetic resonance surveillance of repaired coarctation of the aorta. (scmr.org)
  • Since aortic coarctation was not suspected no gradients in aorta were obtained. (scmr.org)
  • Chest CT revealed coarctation of the aorta, the narrowest portion measuring 7.9 mm in diameter at the proximal descending aorta ( Figures 4 (left) and 5 (right) ). (scmr.org)
  • Clinicians should maintain a certain degree of suspicion for coarctation of the aorta in young patients presenting with hypertension. (scmr.org)
  • Objectives This study sought to evaluate the outcomes of endovascular treatment with covered versus bare Cheatham-platinum stents (NuMed, Hopkinton, New York) in coarctation of aorta (CoA) patients. (onlinejacc.org)
  • Coarctation of the aorta (CoA) is a congenital cardiovascular malformation with relatively low prevalence and is characterized by a narrowing of the thoracic aorta mostly just distal to the left subclavian artery (1,2) . (onlinejacc.org)
  • The left ventricular outflow tract (LVOT) malformations aortic valve stenosis (AVS), coarctation of the aorta (CoA), and hypoplastic left heart syndrome (HLHS) are significant causes of infant mortality. (pubmedcentralcanada.ca)
  • Aortic valve stenosis (AVS), coarctation of the aorta (CoA), and hypoplastic left heart syndrome (HLHS) comprise the group of CVMs that collectively result in obstruction of the left ventricular outflow tract (LVOT). (pubmedcentralcanada.ca)
  • Transthoracic echocardiography is the primary imaging modality for suspected coarctation of the aorta. (minervamedica.it)
  • Coarctation and occlusion of the aorta is a rare condition that typically presents with hypertension or cardiac failure. (jkns.or.kr)
  • Acute aortic coarctation with occlusion of the aorta is rare condition that has an extremely poor prognosis and high incidence of neurovascular complications. (jkns.or.kr)
  • Prenatal diagnosis of coarctation of the aorta with the multiplanar display and B-flow imaging using 4-dimensional sonography. (springerprofessional.de)
  • Mukai, Y., Samura, O., Teraoka, Y., Sasaki, M.: Prenatal diagnosis of coarctation of the aorta using the three-vessel view by calculating the ratio of the diameter of the aortic root to that of the pulmonary artery. (springerprofessional.de)
  • Aortic coarctation is a narrowing of part of the aorta (the major artery leading the heart). (diseasereference.net)
  • Coarctation of the aorta can be cured with surgery. (diseasereference.net)
  • Call your health care provider if you or your child have symptoms of coarctation of the aorta. (diseasereference.net)
  • Aortic coarctation is a congenital condition characterized by narrowing of the aorta. (meta.org)
  • Surgical repair of coarctation of the aorta was performed in 17 infants, median age 14 days, median weight 3.5 kg. (elsevier.com)
  • What is in your experiences and opinion the favourite and best view by echocardiography to visualise type A dissection of aorta and to visualise aortic coarctation? (echojournal.org)
  • Description previously I have posted some elementary images from this case.Now I upload the complete clip including:bicuspid aortic valve (with mild eccentric aortic regurgitatio),aneurysm of the ascending aorta,type A dissection,atrial septal aneurysm and coarctation of the aorta. (echojournal.org)
  • Aortic coarctation is a condition characterized by narrowing of the aorta in an area where the "ductus arteriosus" inserts. (naturalcurefor.com)
  • Coarctation (ko-ahrk-TAY-shun) of the aorta - or aortic coarctation - is a narrowing of the aorta, the large blood vessel that branches off your heart and delivers oxygen-rich blood to your body. (pharmacypedia.org)
  • Coarctation of the aorta is generally present at birth (congenital). (pharmacypedia.org)
  • Coarctation of the aorta may range from mild to severe, and may not be detected until adulthood, depending on how narrowed the aorta is. (pharmacypedia.org)
  • Coarctation of the aorta often occurs along with other heart defects. (pharmacypedia.org)
  • While treatment for coarctation of the aorta is usually successful, it's a condition that requires careful follow-up through infancy and throughout adulthood. (pharmacypedia.org)
  • Coarctation of the aorta symptoms depend on the seriousness of the condition. (pharmacypedia.org)
  • Babies with severe coarctation of the aorta usually begin having signs and symptoms shortly after birth. (pharmacypedia.org)
  • Although aortic coarctation can occur anywhere along the aorta, the coarctation is most often located near a blood vessel called the ductus arteriosus. (pharmacypedia.org)
  • Rarely, coarctation of the aorta may develop later in life. (pharmacypedia.org)
  • Traumatic injury may lead to coarctation of the aorta. (pharmacypedia.org)
  • Rarely, severe hardening of the arteries (atherosclerosis) or a condition causing inflamed arteries (Takayasu's arteritis) may narrow your aorta, leading to aortic coarctation. (pharmacypedia.org)
  • Coarctation of the aorta usually occurs beyond the blood vessels that branch off to your upper body and before the blood vessels that lead to your lower body. (pharmacypedia.org)
  • Coarctation of the aorta often occurs along with other congenital heart defects, although doctors don't know what causes multiple heart defects to form together. (pharmacypedia.org)
  • The aortic valve separates the lower left chamber (left ventricle) of the heart from the aorta. (pharmacypedia.org)
  • Adult Coarctation of Aorta with Bicuspid Aortic Valve. (bvsalud.org)
  • Coarctation of the aorta is a congenital cardiac malformation that can go undiagnosed with only hypertension as a marker of its presence, because clinical signs can be subtle and overlooked if a complete physical examination is not performed. (bvsalud.org)
  • Here we present a case report of 20 year old young male patient with hypertension who was diagnosed to have Coarctation of Aorta and Bicuspid aortic Valve .Our patient was relatively asymptomatic until he presented with headache and exertional dyspnoea. (bvsalud.org)
  • Coarctation of the aorta, or CoA, is the narrowing of th. (5minuteconsult.com)
  • This is called coarctation of the aorta. (medlineplus.gov)
  • The exact cause of coarctation of the aorta is unknown. (medlineplus.gov)
  • We propose a CFD-based approach for the non-invasive hemodynamic assessment of pre- and post-operative coarctation of aorta (CoA) patients. (psu.edu)
  • Coarctation of the aorta (CoA ) is a well-known congenital heart disease (CHD) , which is often associated with several other cardiac and vascular anomalies, such as bicuspid aortic valve (BAV), ventricular septal defect, patent ductus arteriosus and aortic arch hypoplasia. (thepreparedminds.com)
  • In more than half of the cases, coarctation was combined with bicuspid aortic valve, and in approximately half of the cases, it was combined with hypoplasia of the aortic arch or descending aorta. (cdc.gov)
  • In this study Kische and colleagues assess the safety and efficacy of utilizing self-expandable uncovered nitinol stents to percutaneously treat adult ischemic coarctation of the aorta. (isachd.org)
  • The authors conclude that adult coarctation of the aorta treatment by means of a self-expandable uncovered stent is safe and durable. (isachd.org)
  • Myocardial strain pattern progress in patients with Coarctation of the Aorta undergoing aortic stenting. (bvsalud.org)
  • Ventricular function evaluation in coarctation of the aorta ( CoA ) has become more sophisticated and precise with speckle tracking, revealing subclinical changes. (bvsalud.org)
  • Changes included a pressure drop at the aortic isthmus in all patients, increased relative pressures in the aortic arch in patients with residual narrowing after repair, and increased relative pressures in the descending aorta in a patient after patch aortoplasty. (amegroups.com)
  • Time-resolved, 3D phase contrast magnetic resonance imaging (MRI) (4D Flow) was used to assess blood flow in the thoracic aorta of 34 individuals: 26 patients with coarctation (22 after surgery or stent placement) and eight healthy volunteers. (qxmd.com)
  • It also can detect distorted blood flow patterns in the descending aorta after coarctation repair. (qxmd.com)
  • Coronary artery angiography revealed myocardial bridge of left anterior descending coronary artery at middle third and coarctation of aorta. (elsevier.com)
  • Coarctation of the aorta (CoA) is a congenital malformation consisting in a narrowing of the aorta, usually located at the isthmus, and generating a pressure gradient between the aortic arch and the distal thoracic aorta. (biomedcentral.com)
  • Echocardiography showed severe AR within a normal tricuspid valve anatomy, aortic root dilatation (40 mm), left ventricle (LV) dysfunction (ejection fraction 40%) and, through a dorsal approach, a flow acceleration across a kinked segment of the descending aorta (maximum pressure gradient of 31 mmHg) with a post-stenosis mild ectasia (diameter of 38 mm) (Figure 1 ). (biomedcentral.com)
  • Coarctation of the aorta is a birth defect in which a part of the aorta is narrower than usual. (cdc.gov)
  • To learn what it's like to live with this condition or how families are affected, read these real stories from people living with coarctation of the aorta. (cdc.gov)
  • Nicholas was born with a serious heart defect called critical coarctation of th e aorta , a severe narrowing in his aorta cutting off blood flow to the lower half of his body. (cdc.gov)
  • Coarctation of the aorta is a narrowing of part of the aorta (the major artery that supplies oxygenated blood to the entire body). (cdc.gov)
  • Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. (wikipedia.org)
  • Preductal coarctation results when an intracardiac anomaly during fetal life decreases blood flow through the left side of the heart, leading to hypoplastic development of the aorta. (wikipedia.org)
  • Postductal coarctation is most likely the result of the extension of a muscular artery (ductus arteriosus) into an elastic artery (aorta) during fetal life, where the contraction and fibrosis of the ductus arteriosus upon birth subsequently narrows the aortic lumen. (wikipedia.org)
  • Some children born with coarctation of the aorta have other heart defects too, such as aortic stenosis, ventricular septal defect, patent ductus arteriosus or mitral valve abnormalities. (wikipedia.org)
  • In more severe cases, where severe coarctations, babies may develop serious problems soon after birth because not enough blood can get through the aorta to the rest of their body. (wikipedia.org)
  • We found a coexistence of Mahaim fibers, coarctation of aorta and bicuspid valve in a young patient presenting with palpitations and subraventricular tachycardia. (elsevier.com)
  • AimThe aim of this study is to address the presence of hypertension and risk for cardiovascular diseases in patients with Coarctation of the Aorta (CoA) who were treated with endovascular stent placement. (erciyes.edu.tr)
  • The diameter of the ascending aorta was 15 mm, the aortic arch was 10 mm, at the site of the stenosis it was 4.4 mm and after the coarctation it was 12 mm. (rbccv.org.br)
  • Ample dissection was performed with opening of the parietal pleura to expose the aortic arch, left subclavian artery, descending aorta and a large aneurysm (Figure 2) making it necessary to ligate two intercostal arteries involved in the aneurysm. (rbccv.org.br)
  • Background: We evaluated the feasibility and utility of low dose multislice computed tomography (MSCT) angiography as a noninvasive method in detecting anatomic structures of lesion and combined anomalies associated with coarctation of the aorta. (istanbulc.edu.tr)
  • This study explores the use of ratios of the external diameter between the aortic isthmus (AI), ascending aorta (AA) and the descending aortas (DA). (elsevier.com)
  • Additionally, Dr. Ringel served as the sponsor and principal investigator of the multicenter Coarctation of the Aorta Stent Trial (COAST), which for the first time resulted in FDA approval of covered stents for treatment of congenital heart problems, including coarctation of the aorta. (hopkinsmedicine.org)
  • Intermediate Outcomes in the Prospective, Multicenter Coarctation of the Aorta Stent Trial (COAST). (hopkinsmedicine.org)
  • Coarctation of the aorta (CoA) is one of the most common congenital cardiac anomalies that could be corrected by surgery. (elsevier.com)
  • I have a Coarctation of the Aorta which on my last MRA (2006) was narrowed to 1 cm at the descending aorta. (medhelp.org)
  • The aortic caliber normalizes in the distal descending thoracic aorta measuring 1.8 cm. (medhelp.org)
  • These obstructions to forward flow may present alone or in concert, as in the frequent association of a bicuspid aortic valve with coarctation of the aorta. (ahajournals.org)
  • B, Classic radiological signs of coarctation of the aorta: rib notching (white arrows) as seen on a posteroanterior chest x-ray in a patient with coarctation of the aorta. (ahajournals.org)
  • The black arrow points to the Figure 3 silhouette that is created by the combination of a dilated left subclavian artery above and a convex dilated descending aorta below the site of coarctation. (ahajournals.org)
  • C, Three-dimensional reconstruction of a cardiac CT angiogram as viewed from the posteroanterior projection, demonstrating a plethora of dilated intercostal collateral arteries in a patient with coarctation of the aorta. (ahajournals.org)
  • The vertical arrows point to the "diastolic tail," a diastolic pressure gradient at the site of coarctation leading to nearly continuous flow, indicating significant coarctation of the aorta. (ahajournals.org)
  • 1 SAS may also present as part of a complex of obstructive lesions, as in Shone's complex, which frequently includes parachute mitral valve, mitral stenosis, BAV, and coarctation of the aorta. (ahajournals.org)
  • Contrast-enhanced CT images show an 8 cm saccular thoracic aortic aneurysm with active extravasation, hemothorax and hemomediastinum. (appliedradiology.com)
  • Patients may present with aortic wall injury (aneurysm) related to prior CoA repair. (clinicaltrials.gov)
  • Another issue of concern, according to Kenny and Hijazi, is the 8% rate of residual endoleak, which raises the issue of whether a self-expanding stent graft may be more suitable in patients with "a dominant aneurysm without significant residual coarctation. (tctmd.com)
  • The study excluded patients with hypoplasia of the distal aortic arch or aortic isthmus and those with complex CoA: complete near atresia and associated aneurysm. (onlinejacc.org)
  • Aortic arch hypoplasia has been linked to aneurysm formation after coarctation repair, with abnormal blood flow proposed as a mechanism ( 1 ). (onlinejacc.org)
  • Extended aortic arch anastomosis is safe in infancy, leaves no native coarctation shelf tissue in the repaired segment, does not sacrifice the subclavian artery, is useful in hypoplastic isthmus, and is at low risk to develop aneurysm or recoarctation. (elsevier.com)
  • Recently, it has been shown that mutations in the NOTCH1 gene can lead to bicuspid aortic valve, aortic aneurysm, and hypoplastic left heart syndrome. (cdc.gov)
  • Complications include arterial hypertension, recurrent coarctation, aneurysm formation and premature atherosclerosis. (amegroups.com)
  • For example, age at surgery, coexistence of bicuspid aortic valve, residual pressure gradient, hypoplastic aortic arch and patient size are related to recurrence of coarctation or aneurysm formation ( 3 , 4 ). (amegroups.com)
  • Aortic coarctation complicated with spinal artery aneurysm rupture is exceptionally rare and can be source of intraspinal hemorrhage with markedly poor prognosis. (elsevier.com)
  • Hypertensive vascular complications, cerebrovascular hemorrhages, aortic aneurysm, aortic dissection or rupture, aortic valve deterioration, premature coronary disease are the most frequent life-threatening complications. (biomedcentral.com)
  • In elderly patients with aortic coarctation who are at risk of an aortic wall aneurysm and rupture, covered stents are preferred but in younger patients, bare metal stenting may be sufficient for long-term safety. (elsevier.com)
  • The GenTAC Registry facilitated research in the diagnosis and clinical care of people who have genetically triggered thoracic aortic aneurysm. (nih.gov)
  • The Registry enrolled over 3,600 people who had one of the 13 conditions with a genetic risk of developing thoracic aortic aneurysm and its complications. (nih.gov)
  • Most frequent cause of PVH and congestive heart failure in 2nd and 3rd weeks of life associated with, bicuspid aortic valve (50-80%), calcific aortic stenosis (due to bicuspid valve), patent ductus arteriosus or VSD (in most) see also: abdominal aortic coarctation. (drugs.com)
  • A prominent left ventricular border often occurs with coarctation, particularly when a bicuspid aortic valve is associated with aortic stenosis. (medscape.com)
  • Gonadal dysgenesis (Turner syndrome), patent ductus arterisus, ventricular septal defect, bicuspid aortic valve, mitral stenosis or regurgitation or aneurysms of the circle of Willis. (thefreedictionary.com)
  • See Aortic stenosis . (thefreedictionary.com)
  • In 7/4945 included articles, 123 and 76 patients with congenital aortic stenosis (CAS) and CoA were reported, respectively. (diva-portal.org)
  • The baseline degree of stenosis associated with the coarctation can be documented, and patients can then be appropriately managed to prevent future morbidity and mortality. (scmr.org)
  • To assess the effects on the biosynthesis of collagen types I and III associated with an acute increase in blood pressure, we established a mid-thoracic aortic coarctation in the rabbit and studied gene expression and protein accumulation of these collagen types proximal to the stenosis 1, 3 and 7 days and 2, 4 and 8 weeks after coarctation. (ovid.com)
  • In the current era, patients with CoA continue to have a reduced life expectancy and an increased risk of cardiovascular sequelae later in life, despite adequate relief of the aortic stenosis. (thepreparedminds.com)
  • Aortic coarctation and aortic stenosis are both forms of aortic narrowing. (wikipedia.org)
  • This spectrum is dichotomized by the idea that aortic coarctation occurs in the aortic arch, at or near the ductus arteriosis, whereas aortic stenosis occurs in the aortic root, at or near the aortic valve. (wikipedia.org)
  • A, Gradient echo cardiac MR image as viewed from the frontal projection demonstrating flow acceleration at a site of supravalvar aortic stenosis (white arrow) in a patient with Williams syndrome. (ahajournals.org)
  • The diameter at the site of aortic narrowing is measured so that the proper size stent, an expandable slotted metal tube, can be selected. (ucsfhealth.org)
  • However, in those with native, complex and long segment coarctation, the Task Force maintains that there is a paucity of safety data to support stent use. (tctmd.com)
  • Aortic wall injury as a result of bare metal stent implantation, or as a late complication, remains a concern and is the primary appeal of a covered stent. (tctmd.com)
  • Stent placement is commonly used to treat aortic coarctation. (ovid.com)
  • Normal and abnormal computed tomographic appearance of different stent types is shown along with reconstructions that can help assess stent integrity and the stent position in relation to the aortic wall and branches. (ovid.com)
  • She underwent implantation of a self-expanding aortic stent and therefore the systolic pressure gradient decreased from 90 to 15 mmHg. (ac.ir)
  • In long-term follow up, aortic computed tomography confirmed the absence of stent collapse and secondary migration and documented stability in aortic diameter. (isachd.org)
  • The peculiar stent design maintains adequate localized radial strength over time with minimal trauma on the adjacent aortic wall and negligible device-related complications. (isachd.org)
  • The aortic dissections and ruptures were treated successfully by deploying an additional covered stent proximal to the site of dissection or rupture. (northwestern.edu)
  • Is hypertension the fate of aortic coarctation patients treated with Cheatham Platinum (CP) stent? (erciyes.edu.tr)
  • Herein we present a 47-year-old typical aortic coarctation patient who was successfully treated with a bare metal stent. (elsevier.com)
  • By subjectively scoring CT scans for image quality and measuring the amount of stent-induced blooming artefacts, the authors were able to conclude there is a substantial variation in CT image quality and blooming artefacts for different stent types used to treat aortic coarctation. (er-x.org)
  • The diagnosis of coarctation generally can be made on the basis of physical examination. (medscape.com)
  • Diagnosis is made by demonstration of aortic arch narrowing, typically by echocardiography. (bmj.com)
  • We propose to use a lumped model of the fetal circulation to provide insights into the hemodynamic changes in fetuses with aortic coarctation, and thus helping to improve its diagnosis. (springerprofessional.de)
  • Difficult prenatal diagnosis: fetal coarctation. (springerprofessional.de)
  • By providing clinical and biological data, the GenTAC Registry is helping improve the diagnosis and clinical care of genetically triggered thoracic aortic aneurysms and their complications, especially those affecting the cardiovascular system. (nih.gov)
  • associated anomalies of the mitral and aortic valve may also be demonstrated. (medscape.com)
  • ECG-gated studies better demonstrate associated cardiac findings, such as bicuspid aortic valve, left ventricular hypertrophy, and ventricular septal defect. (appliedradiology.com)
  • possible findings include systolic thrill palpable in the suprasternal notch, LV hypertrophy, systolic ejection click due to bicuspid aortic valve, harsh systolic ejection murmur along the left strernal border and a systolic murmur heard in the back EKG LV hypertrophy. (thefreedictionary.com)
  • Moderate and severe aortic valve disease was more common in BAV type-0 compared with BAV type-1 (p = 0.030) and TAV (p = 0.016). (diva-portal.org)
  • Development of aortic valve disease is more common in BAV type-0 than in BAV type-1. (diva-portal.org)
  • It is often associated with a diffuse arteriopathy and bicuspid aortic valve. (bmj.com)
  • Coarctation can occur in isolation, in association with bicuspid aortic valve or with major cardiac malformations. (clinicaltrials.gov)
  • Transthoracic echocardiogram showed a bicuspid aortic valve with severe aortic regurgitation (50% regurgitant fraction) ( Figure 2 ) and an eccentric jet directed toward the anterior mitral valve leaflet. (scmr.org)
  • The aortic valve appears like a true bicuspid valve, with fusion of the right coronary and left-coronary aortic cusps and a small rudimentary raphae ( Figure 11 ). (scmr.org)
  • Rupture of an aneurysmal aortic diverticulum associated with coarctation and bicuspid aortic valve. (ox.ac.uk)
  • However, it can also be due to birth defects of the aortic valve, such as a bicuspid aortic valve. (diseasereference.net)
  • Bicuspid aortic valve. (pharmacypedia.org)
  • A bicuspid aortic valve has two leaflets instead of the usual three. (pharmacypedia.org)
  • The aim of our study was to estimate the frequency of NOTCH1 gene mutations/substitutions in patients with aortic coarctation, isolated or combined with bicuspid aortic valve. (cdc.gov)
  • Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms. (cdc.gov)
  • Novel missense mutations (p.T596M and p.P1797H) in NOTCH1 in patients with bicuspid aortic valve. (cdc.gov)
  • Cardio-surgery consult indicated surgical repair of the aortic valve and no treatment for the CoA. (biomedcentral.com)
  • Bicuspid aortic valve is an aortic valve that has two leaflets, instead of three. (cdc.gov)
  • There is no intervention for his bicuspid aortic valve. (cdc.gov)
  • A bicuspid aortic valve is present in 50 percent. (mhmedical.com)
  • Bicuspid aortic valve is found in 50 percent of infants, with left ventricular outflow tract obstruction (LVOTO) often seen because of hypoplasia of the aortic root or posterior malalignment of the infundibular septum. (mhmedical.com)
  • The black arrow identifies the level of the unrestricted aortic valve. (ahajournals.org)
  • E, Autopsy specimen of a calcified and stenotic bicuspid aortic valve. (ahajournals.org)
  • A bicuspid aortic valve (BAV) is present in 23% of patients. (ahajournals.org)
  • 1 In addition, other sequelae related to chronic hypertension, such as coronary artery disease, stroke and aortic dissection can also develop. (appliedradiology.com)
  • Five levels of severity have been defined for each of the 3 illness categories, including: Upper extremity hypertension, Upper to lower extremity pressure difference, and Severity of aortic wall injury. (clinicaltrials.gov)
  • Native CoA or re-coarctation was diagnosed if systemic hypertension and/or an arm-to-leg pressure gradient ≥20 mm Hg were present, and CoA was confirmed with magnetic resonance imaging (MRI). (onlinejacc.org)
  • Ductal aortic coarctation is more common in adults and is associated with hypertension, weak pulses in lower extremeties and notching of the ribs. (naturalcurefor.com)
  • Patients with aortic coarctation develop arterial hypertension in their right arm with normal (or low) blood pressure in their lower extremities. (naturalcurefor.com)
  • If aortic coarctation is asymptomatic, but shows arterial hypertension, it could still require surgical resection of the narrow segment. (naturalcurefor.com)
  • Aortic coarctation left untreated may lead to permanent arterial hypertension because of irreversible changes in the patients' organs. (naturalcurefor.com)
  • A history of hypertension at young age and aortic regurgitated murmurs may serve as clues for further diagnostic studies. (elsevier.com)
  • 20 mmHg between upper and lower limbs or hypertension associated with a ≥ 50% narrowing relative to the reference aortic diameter (diaphragm level). (biomedcentral.com)
  • Is hypertension the fate of aortic coarc. (erciyes.edu.tr)
  • A corresponding calculation of delta arterial saturation and comparison of plethysmograph shape parameters between multiple sites is particularly advantageous for the detection and management of persistent pulmonary hypertension in neonates (PPHN), a patent ductus arteriosis (PDA), and aortic coarctation. (freepatentsonline.com)
  • Severe cases of preductal coarctation, blood flow to the lower body to the narrowing could become dependent on a patent ductus arteriosus. (naturalcurefor.com)
  • Resection of the internal shelf through a longitudinal aortotomy and widening with the free end of the left in situ internal mammary artery (IMA) were steps in correction of aortic coarctation with isthmus hypoplasia in nine patients aged 9-14 (mean 10.5) years. (biomedsearch.com)
  • Time-resolved, 3-dimensional phase-contrast magnetic resonance imaging (4-dimensional flow) allowed dynamic visualization of flow and computation of vectorial wall shear stress in 5 patients after coarctation repair, 4 with arch hypoplasia ( 2 ). (onlinejacc.org)
  • Four-dimensional flow was used to visualize systolic blood flow and calculate wall shear stress in 5 patients after coarctation repair, 4 with arch hypoplasia. (onlinejacc.org)
  • Magnetic resonance angiography with corresponding cross-sectional analysis at the planes indicated demonstrate eccentric systolic flow resulting in focally elevated wall shear stress in 3 patients with arch hypoplasia after coarctation repair, 2 with repair site aneurysms (A, B) . Dynamic visualization of blood flow with a particle trace for case A can be found as Online Video 1 . (onlinejacc.org)
  • She underwent a cineangiography which located coarctation across the subclavian artery root and identified moderate aortic arch hypoplasia. (rbccv.org.br)
  • The use of fabric-covered CP Stents to prevent or repair aortic wall injury has become the treatment of choice in Europe and recently in the US through the FDA Compassionate Use process. (clinicaltrials.gov)
  • COAST II will test safety and efficacy of Covered CP Stents to repair or prevent aortic wall injury associated with CoA. (clinicaltrials.gov)
  • Since that time, bare metal stents have been advocated by the American College of Cardiology/American Heart Association Task Force as the preferred strategy for patients with recurrent coarctation. (tctmd.com)
  • According to Taggart et al, prior to their study, there have been no standardized clinical trials of aortic coarctation treated with covered stents. (tctmd.com)
  • In brief, Palmaz stents P4014 and P308 (Johnson & Johnson International Systems, Warren, New Jersey) dilatable to an adult aortic diameter were implanted. (onlinejacc.org)
  • The aim of this study was to evaluate the post-implantation computed tomography (CT) image quality of different types of stents that are used to treat aortic coarctation. (er-x.org)
  • In this review, we identify the challenges associated with and the optimal management for recurrent aortic coarctation and the most appropriate therapy for different patient cohorts. (springer.com)
  • Volume-rendered images demonstrate prominent internal thoracic and intercostal arteries along with a moderate-sized spinal artery originating immediately distal to the coarctation ( Figure 10 ). (scmr.org)
  • Follow-up two-dimensional echocardiographic and Doppler studies on 13 patients 1 to 56 months after surgery demonstrated normal distal aortic flow in 10, slightly decreased flow in two, and diminished flow in one. (elsevier.com)
  • An embryologic remnant of the distal portion of the sixth left branchial arch, the ductus arteriosus is usually on the left side, but in cases of right aortic arch, it can be on either side. (mhmedical.com)
  • Postductal coarctation: The narrowing is distal to the insertion of the ductus arteriosus. (wikipedia.org)
  • In this condition there is anatomic lack of continuity in the aortic arch, classified according to the site of occurrence into type A (distal to left subclavian), type B (between the left common carotid and subclavian), and type C (just distal to the innominate artery). (mhmedical.com)
  • Now it is often possible to correct coarctation without surgery in a procedure called a cardiac catheterization. (ucsfhealth.org)
  • Infants with severe coarctation have cardiac enlargement and pulmonary congestion. (medscape.com)
  • If the narrowing is severe, it may present in the newborn period once the ductus arteriosus closes as low cardiac output and shock (critical coarctation). (bmj.com)
  • Aortic coarctation is one of the most difficult cardiac defects to diagnose before birth, and it accounts for 8% of congenital heart diseases. (springerprofessional.de)
  • Axillo-iliac bypass is a surgical option for coarctation that can reduce cardiac afterload. (elsevier.com)
  • Posted in Computed Tomography , Magnetic Resonance Imaging and tagged Aortic coarctation , CARDIAC PROCEDURES AND THERAPY , Congenital heart disease , DISEASES . (thepreparedminds.com)
  • These findings suggest that blood pressure abnormalities could be due both to the altered baroceptor reflex control mechanism, resulting in cardiac output and total peripheral vascular resistance abnormalities, and to the progressive increase in resistance during exercise at the site of the repair, resulting in the higher PP, that may be related to a local loss of the natural aortic elasticity. (elsevier.com)
  • The severity of aortic coarctation (CoA) may be underestimated during cardiac catheterization. (thechipnetwork.org)
  • Objective: The objective of this study was to evaluate outcomes of endovascular treatment of aortic coarctation in adults. (northwestern.edu)
  • Open surgery provides a durable long-term aortic repair, however, given the complex nature of the procedure, has a somewhat higher rate of serious complications. (springer.com)
  • Such changes in the cushioning function appear responsible for many clinical features and complications of aortic coarctation. (ahajournals.org)
  • Conventional treatment of native CoA is surgical repair, however potential recurrence or other related complications e.g. aortic rupture, heart failure and cerebrovascular events are common. (diva-portal.org)
  • Furthermore, imaging findings of complications including aortic wall injuries, restenosis, and intimal hyperplasia are depicted. (ovid.com)
  • The technique might allow identifying pathophysiological conditions underlying complications after aortic coarctation repair. (amegroups.com)
  • Only few previous studies described factors associated with the occurrence of complications after aortic coarctation repair. (amegroups.com)
  • Conclusions: Endovascular repair is effective with an acceptable safety profile in the treatment of NCO and postsurgical complications of coarctation after initial OSR. (northwestern.edu)
  • A computed tomography excluded aortic dissection. (elsevier.com)
  • Aortic coarcation can cause paralysis by ruptured vascular aneurysms with spinal hemorrhage and chest pain that mimics acute aortic dissection. (elsevier.com)
  • Such changes were responsible for characteristic alteration in central aortic pressure pulse contour and for change in other parameters, indicating impaired arterial function in accepting pulsatile flow from the heart. (ahajournals.org)
  • The aim of this study was to determine the outcome after surgical repair of aortic coarctation in adults, analysing its effect on arterial blood pressure. (viamedica.pl)
  • There are no current guidelines to prevent aortic coarctation because it is a congenital defect. (epnet.com)
  • Since aortic coarctation is a congenital defect, it cannot be prevented. (stdavids.com)
  • Gentles TL, Sanders SP, Colan SD (2000) Misrepresentation of left ventricular contractile function by endocardial indexes: clinical implications after coarctation repair. (springer.com)
  • A parametric study of degree and type of coarctation was performed, where blood flow distribution, cerebroplacental ratio, pressure drop over the coarctation and left ventricular pressure were quantified. (springerprofessional.de)
  • Left ventricular outflow tract obstructions (LVOTOs) encompass a series of stenotic lesions starting in the anatomic left ventricular outflow tract (LVOT) and stretching to the descending portion of the aortic arch ( Figure 1 ). (ahajournals.org)
  • Aortic coarctation is a local narrowing of the aortic lumen, which is located at the level of the isthmus in 95% of patients. (minervamedica.it)
  • Auscultation revealed an aortic systolic murmur with radiation to the back. (bmj.com)
  • From these data were derived input impedance of the systemic circulation, pulsatile and steady components of external heart work, aortic systolic pressure-time index, and mean systolic and mean diastolic pressures. (ahajournals.org)
  • Magnetic resonance angiography, systolic streamlines and cross-sectional analysis at the plane indicated, with relative shear stress represented by green bars , exhibit normal flow in a patient with normal arch geometry after coarctation repair. (onlinejacc.org)
  • Her heart rhythm was regular with a heart rate of 64 bpm, systolic murmur of ++/4+ at an accessory aortic focus. (rbccv.org.br)
  • D, Continuous-wave Doppler signal through the site of coarctation with a systolic flow velocity of 3.4 m/s (Syst) and a peak pressure gradient of 46 mm Hg. (ahajournals.org)
  • Two additional patients died during follow-up of coarctation-related causes, including rupture of an infected graft and visceral ischemia. (northwestern.edu)
  • Aortic rupture is an infrequent (2%) but devastating complication with high mortality. (northwestern.edu)
  • A computed tomography (CT) angiogram ( Fig. 2 ) showed a tortuous aortic coarctation with an extensive network of collaterals. (jkns.or.kr)
  • The computed tomography angiogram reveals a tortuous aortic coarctation (white arrow) with an extensive network of collaterals (arrowheads). (jkns.or.kr)
  • Maximum intensity projection magnetic resonance angiography is provided to demonstrate aortic arch geometry in all cases. (onlinejacc.org)
  • Aortic coarctation can be diagnosed accurately through magnetic resonance angiography. (naturalcurefor.com)
  • Since aortic coarctation in adults usually reach the lower body, these could be seen by angiography or MR. (naturalcurefor.com)
  • Three different imaging modalities (echocardiography (Figure 1), CT angiography (Figure 2), conventional aortography (Figure 3) confirmed the aortic coarctation at 30 mm after left subclavian artery origin, with the 3.5-4 mm diameter of the narrowest segment. (ac.ir)
  • Measuring aortic diameter with different MR techniques: comparison of three-dimensional (3D) navigated steady-state free-precession (SSFP), 3D contrast-enhanced magnetic resonance angiography (CE-MRA), 2D T2 black blood, and 2D cine SSFP. (qxmd.com)
  • Clinical implication of parameter-optimized 3D-FISP MR angiography (MRA) in children with aortic coarctation: comparison with catheter angiography]. (qxmd.com)
  • Pulsed and continuous-wave Doppler study may be used to determine the pressure gradient directly at the area of coarctation. (medscape.com)
  • 8 The American Heart Association recommends treatment when there is a pressure gradient of 20 mm Hg or greater, or the presence of significant coarctation with significant collateral flow, with or without a 20 mm Hg or greater pressure gradient. (appliedradiology.com)
  • There was a pressure gradient across the coarctation relative to the aortic arch that was not accurately quantified due to technical difficulties. (scmr.org)
  • Preoperative catheterization showed a 45-mmHg aortic pressure gradient and ventricular end-diastolic pressure of 11 mmHg. (elsevier.com)
  • Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. (nih.gov)
  • An experimental model of aortic coarctation in rhesus monkeys. (bvsalud.org)
  • abstract = "A 13-year-old girl, who had undergone interrupted aortic arch repair with an 8-mm graft as a neonate and Fontan completion in childhood, developed ventricular fibrillation due to long-QT syndrome. (elsevier.com)
  • abstract = "Aortic coarctation is a correctable hypertensive disease. (elsevier.com)
  • abstract = "Aortic Coarctation (AC) is associated with sudden infantile death. (elsevier.com)
  • There are CoA patients with clinical situations that place them at high risk of aortic wall injury during bare metal stenting. (clinicaltrials.gov)
  • Two clinical cases of patients suffering from aortic coarctations (CoA) were built and parameterized based on clinical data under pre-treatment conditions. (frontiersin.org)
  • 4D flow MR imaging has shown promise in the evaluation of both the clinical significance of the coarctation through the demonstration of collateral blood flow and the persistence of helical flow after coarctation repair. (scmr.org)
  • Clinical evaluation of aortic coarctation with 4D flow MR imaging. (scmr.org)
  • Once clinical signs are identified, imaging can be used to diagnose aortic coarctation evaluate for other associated anatomic abnormalities that put the patient at risk for development of chronic conditions such as heart failure or acute conditions such as intracranial hemorrhage. (scmr.org)
  • 4D flow MRI data of four patients with aortic coarctation either before or after repair (mean age 17 years, age range 3-28, one female, three males) and four young healthy volunteers without history of cardiovascular disease (mean age 24 years, age range 20-27, one female, three males) was acquired using a 1.5-T clinical MR scanner. (amegroups.com)
  • From 2009 to 2016, the GenTAC Registry held four scientific meetings called Aortic Summits, which help bring together clinical, translational, and basic scientists who research the genetic and other factors involved in the mechanisms of thoracic aortic disease, as well as its progression and treatment. (nih.gov)
  • 6 In the infant, the original surgical technique of resection and end-to-end anastomosis remains the preferred treatment 6 while in older children and adults, there are a variety of approaches, including placement of an aortic graft and endovascular stenting. (appliedradiology.com)
  • Extended end-to-end aortic arch anastomosis was used. (elsevier.com)
  • Video 1 Time-resolved color-coded pressure difference maps of the patient named "patient 2" in Table 1 , an 11-year-old male patient after resection of aortic coarctation and end-to-end anastomosis. (amegroups.com)
  • However, the effects of surgical anastomosis on aortic arch flow are still unknown. (elsevier.com)
  • In this study, a unique three-dimensional way was utilized to measure the growth of anastomotic site and computational fluid dynamics (CFD) was applied to investigate the hemodynamic effects of the growth of anastomosis site on patient-specific aortic arch flow before, 1 year and 2 years after surgery. (elsevier.com)
  • Our results implied that the numerical methods can be applied to evaluate the long-term effects of anastomosis site growth on aortic arch flow. (elsevier.com)
  • 2. Lam YY, Kaya MG, Li W, Mahadevan VS, Khan AA, Henein MY, Mullen M. Effect of endovascular stenting of aortic coarctation on biventricular function in adults. (scmr.org)
  • Endovascular intervention was recommended, and the patient was referred for surgical repair of the aortic coarctation. (jkns.or.kr)
  • Hemodynamically significant coarctation is usually treated by surgical or endovascular repair which greatly reduce morbidity ( 1 , 2 ). (amegroups.com)
  • Thirty-two patients had NCO (mean age, 48 ± 16 years) and 61 had endovascular reinterventions after prior OSR during childhood (mean, 30 ± 17 years after initial repair), including 50 patients (54%) with recurrent coarctation and 11 (12%) with ANE. (northwestern.edu)
  • He underwent thoracic endovascular aortic repair uneventfully. (elsevier.com)
  • Obvious changes in the fetal hemodynamics were observed only from 80% of coarctation, corresponding to the clinically used cut-off for pressure drop of 20 mmHg. (springerprofessional.de)
  • Flow-sensitive in-vivo 4D MR imaging at 3T for the analysis of aortic hemodynamics and derived vessel wall parameters]. (qxmd.com)
  • Echo now demonstrates only mild to moderate aortic regurgitation. (scmr.org)
  • We report the case of an elderly patient with history of congestive heart failure (CHF) and aortic regurgitation (AR) who was referred for progressive exertional dyspnoea. (biomedcentral.com)
  • Factors associated with arch reintervention and growth of the aortic arch after coarctation repair in neonates weighing less than 2.5 kg. (springer.com)
  • There are three types of aortic coarctation - preductal, ductal and postductal coarctation. (naturalcurefor.com)
  • citation needed] Play media There are three types of aortic coarctations: Preductal coarctation: The narrowing is proximal to the ductus arteriosus. (wikipedia.org)
  • Flow-sensitive four-dimensional magnetic resonance imaging: flow patterns in ascending aortic aneurysms. (qxmd.com)
  • From 2006 to 2016, the NHLBI and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) co-funded the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC). (nih.gov)
  • The purpose of the GenTAC Registry was to collect data and specimens from patients who had a confirmed or suspected genetic condition that increased their chances of developing thoracic aortic aneurysms . (nih.gov)
  • By supporting the scientific community, the GenTAC Registry successfully promoted scientific collaborations and fostered research on thoracic aortic aneurysms. (nih.gov)
  • Data have indicated that many thoracic aortic aneurysms in people younger than 50 are due to mutations in the genes. (nih.gov)
  • They found that the distance between the mitral and aortic valves in patients with SAS is consistently increased. (ahajournals.org)
  • While coarctation and hypoplastic left heart syndrome are observed in this syndrome, this is the second reported case of aLPA in KS and the first with the forme fruste of left-sided obstruction as well as aLPA in this group of patients. (kabukisyndrome.com)
  • Here, we report a 49-year-old male patient diagnosed with abdominal aortic coarctation together with the review of the literature. (biomedsearch.com)
  • View our YouTube playlist , which highlights genetics, imaging, and surgery options for thoracic aortic disease and research done using GenTAC data, biospecimens, or images. (nih.gov)
  • Read more about how the GenTAC Registry continues to increase knowledge about thoracic aortic disease through Aortic Summits. (nih.gov)
  • In the past, coarctation repair always involved heart surgery through an incision in the side of the chest that required five to seven days in the hospital for recovery. (ucsfhealth.org)
  • The incidence of recurrent coarctation requiring intervention was 19.3% in 2V vs. 9.7% in SV patients (P = 0.01) at a median of 0.5 (interquartile range 0.3-1.2) years from initial surgery. (nih.gov)
  • Most of the time, surgery to fix the coarctation is done during infancy. (diseasereference.net)
  • Undiagnosed congenital abnormalities, such as aortic coarctation and occlusion, should be considered for patients presenting with nontraumatic paraplegia in the absence of other identifiable causes. (jkns.or.kr)
  • Aortic coarctation may or may not have symptoms. (epnet.com)
  • Aortic coarctation has signs and symptoms and radiographic findings that are diagnostic. (appliedradiology.com)
  • What Are the Symptoms of Aortic Coarctation? (aarpmedicareplans.com)
  • Children with serious aortic narrowing tend to show signs and symptoms earlier in life, while mild cases may not be diagnosed until adulthood. (pharmacypedia.org)
  • Symptoms may be absent with mild narrowings (coarctation). (wikipedia.org)
  • Furthermore, successful percutaneous intervention in treating coarctation and catheter-based ablation of Mahaim fibers were performed with resolution of symptoms. (elsevier.com)
  • The suspicion of congenital postductal aortic coarctation was confirmed by transoesophageal echocardiography. (bmj.com)
  • aortic coarctation with a mean gradient of 108 mmHg was diagnosed at echocardiography. (rbccv.org.br)
  • The patient was referred for MRI to further define the anatomic location of the coarctation. (scmr.org)
  • The above mentioned patient will require lifelong surveillance of both his aortic root and coarctation. (scmr.org)
  • To achieve this goal a patient-specific lumped model of the fetal circulation was implemented in OpenCOR, including the modeling of different types and degrees of aortic coarctation. (springerprofessional.de)
  • Three Different Imaging Modalities of a Patient with the Aortic Coarctation', Journal of Cardio-Thoracic Medicine , 5(1), pp. 556-557. (ac.ir)
  • When a patient has a coarctation, the left ventricle has to work harder. (wikipedia.org)
  • therefore severe coarctation can be life-threatening. (wikipedia.org)