Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.Aorta, Thoracic: The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.Aortography: Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.Sternotomy: Making an incision in the STERNUM.Aorta, Abdominal: The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.Angioplasty, Balloon: Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.Polydioxanone: An absorbable suture material used also as ligating clips, as pins for internal fixation of broken bones, and as ligament reinforcement for surgically managed ligament injuries. Its promising characteristics are elasticity, complete biodegradability, and lack of side effects such as infections.Neurocutaneous Syndromes: A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.Heart Septal Defects, Ventricular: Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.Cardiovascular Surgical Procedures: Surgery performed on the heart or blood vessels.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Cardiac Surgical Procedures: Surgery performed on the heart.Aortic Arch Syndromes: Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.Vascular Surgical Procedures: Operative procedures for the treatment of vascular disorders.Subclavian Artery: Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.Blood Vessel Prosthesis Implantation: Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.Aorta: The main trunk of the systemic arteries.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Bronchial Fistula: An abnormal passage or communication between a bronchus and another part of the body.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Aortic Aneurysm, Thoracic: An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Infant, Newborn: An infant during the first month after birth.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Abnormalities, MultipleFollow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Thoracotomy: Surgical incision into the chest wall.Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.Renal Artery Obstruction: Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).Endarterectomy: Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY.Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.Leriche Syndrome: A condition caused by occlusion of terminal aorta, the primary branches of the ABDOMINAL AORTA, as in aortoiliac obstruction. Leriche syndrome usually occurs in males and is characterized by IMPOTENCE, absence of a pulse in the femoral arteries, weakness and numbness in the lower back, buttocks, hips, and lower limbs.Hospitals, Voluntary: Private, not-for-profit hospitals that are autonomous, self-established, and self-supported.Patient Care Team: Care of patients by a multidisciplinary team usually organized under the leadership of a physician; each member of the team has specific responsibilities and the whole team contributes to the care of the patient.Hospitals, Proprietary: Hospitals owned and operated by a corporation or an individual that operate on a for-profit basis, also referred to as investor-owned hospitals.Accreditation: Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.Library Services: Services offered to the library user. They include reference and circulation.Certification: Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty.Libraries, Medical

Inhibition of beta-myosin heavy chain gene expression in pressure overload rat heart by losartan and captopril. (1/563)

AIM: To study the effects of losartan and captopril on beta-myosin heavy chain (MHC), and alpha-MHC gene expression. METHODS: Pressure overload was produced by abdominal aortic coarctation (AAC) in rats. alpha- and beta-MHC mRNA were measured by Northern blot. RESULTS: In left ventricular myocardium of sham-operated rats, the alpha-MHC mRNA predominated, while the beta-MHC mRNA was only detectable. In response AAC, there was a 70-fold increase in the beta-MHC mRNA (P < 0.01), while alpha-MHC mRNA reduced to 26% (P < 0.01). Losartan (3 mg.kg-1.d-1, i.g. for 11 d) to AAC rats caused inhibitions of beta-MHC by 96% and alpha-MHC by 86% gene expression without lowering blood pressure. A reduction in beta-MHC mRNA was also seen in captopril-treated rats (30 mg.kg-1.d-1, i.g. for 11 d), but the inhibitory effect of captopril on alpha-MHC mRNA was less than that of losartan (44% vs 86%, P < 0.05). CONCLUSIONS: The shift of MHC isoform induced by pressure overload is due to up-regulation of beta-MHC and down-regulation of alpha-MHC gene expression. Inhibition of beta-MHC gene expression by losartan is achieved primarily by direct blockade of angiotensin II type I receptors in the myocardium, independent on hemodynamics.  (+info)

Biventricular repair approach in ducto-dependent neonates with hypoplastic but morphologically normal left ventricle. (2/563)

OBJECTIVES: Increased afterload and multilevel LV obstruction is constant. We assumed that restoration of normal loading conditions by relief of LV obstructions promotes its growth, provided that part of the cardiac output was preoperatively supported by the LV, whatever the echocardiographic indexes. BACKGROUND: Whether to perform uni- or biventricular repair in ducto dependent neonates with hypoplastic but morphologically normal LV (hypoplastic left heart syndrome classes II & III) remains unanswered. Echocardiographic criteria have been proposed for surgical decision. METHODS: Twenty ducto dependent neonates presented with this anomaly. All had aortic coarctation associated to multilevel LV obstruction. Preoperative echocardiographic assessment showed: mean EDLW of 12.4 +/- 3.03 ml/m2 and mean Rhodes score of -1.73 +/-0.8. Surgery consisted in relief of LV outflow tract obstruction by coarctation repair in all associated to aortic commissurotomy in one and ASD closure in 2. RESULTS: There were 3 early and 2 late deaths. Failure of biventricular repair and LV growth was obvious in patients with severe anatomic mitral stenosis. The other demonstrated growth of the left heart. At hospital discharge the EDLVV was 19.4+/-3.12 ml/m2 (p = 0.0001) and the Rhodes score was -0.38+/-1.01 (p = 0.0003). Actuarial survival and freedom from reoperation rates at 5 years were 72.5% and 46%, respectively. CONCLUSIONS: Biventricular repair can be proposed to ducto dependent neonates with hypoplastic but morphologically normal LV provided that all anatomical causes of LV obstruction can be relieved. Secondary growth of the left heart then occurs; however, the reoperation rate is high.  (+info)

A family study of coarctation of the aorta. (3/563)

Families of 100 patients with coarctation of the aorta and 50 controls for age, sex, and social status were studied to assess the influence of genetic and environmental variables in the aetiology. A tendency to familial aggregation of the condition and other congenital heart defects compatible with multifactorial inheritance was discerned. Recurrence risk for sibs is approximately 1 in 200 for coarctation of the aorta, and 1% for any form of congenital heart defect. The heritability of coarctation is estimated at 58%. The tendency for other non-cardiac defects to occur in the patients with coarctation does not appear in their sibs and is not so pronounced as in some other congenital heart conditions. Of the several environmental variables examined, there was no definitive association with any other than season of birth, which implies a possible association with maternal infection; there is also a suggestion of a paternal age effect, but these require investigation in a prospective survey.  (+info)

Long-term effects of balloon angioplasty on systemic hypertension in adolescent and adult patients with coarctation of the aorta. (4/563)

AIMS: To define the long-term effect of balloon angioplasty of aortic coarctation on hypertension, in adolescent and adult patients. METHODS: Balloon angioplasty of discrete, native aortic coarctation was performed on 50 patients (34 male) aged 23+/-8 (mean+/-standard deviation) years. In 42 of these patients cardiac catheterization and angiography were repeated 1 year later, and on the basis of sphygmomanometric blood pressure determination at that time, they were divided into 31 patients (group A) with normalized blood pressure and 11 patients (group B) who still needed antihypertensive medication. Both groups were followed annually thereafter for 12-123 (66+/-37) months. RESULTS: Coarctation gradient values before, immediately after and 1 year after angioplasty were 69+/-24 mmHg, 12+/-8 mmHg (P<0.001) and 7+/-6 mmHg. The corresponding systolic blood pressure values were 165+/-17 mmHg, 128+/-12 mmHg (P<0.001) and 115+/-10 mmHg (P<0.001) in group A; 182+/-21 mmHg, 141+/-24 mmHg (P<0.001) and 134+/-18 mmHg (P<0.001) in group B. Echocardiographic left ventricular mass index before angioplasty and at follow-up was 130+/-31 g x m-2 and 105+/-23 g x m-2 in group A; 157+/-38 g x m-2 and 132+/-35 g x m-2 in group B (P<0.001 for both comparisons). CONCLUSION: Normalization of blood pressure without medication occurred in 74% of patients after angioplasty for aortic coarctation, with subsequent long-term regression of left ventricular hypertrophy. In comparison to reported surgical results, balloon angioplasty should be considered as first line treatment for native, discrete aortic coarctation in adolescent and adult patients.  (+info)

Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses. (5/563)

We studied in anesthetized rats whether aminopeptidase P (AMP) may be involved in bradykinin (BK) metabolism and responses. For this we inhibited AMP with the specific inhibitor apstatin (Aps). Studies were done with Aps alone or together with the angiotensin-converting enzyme inhibitor lisinopril (Lis). Aps increased the vasodepressor response to an intravenous bolus of BK (400 ng/kg): vehicle, -3.0 +/- 0.7 mmHg; Aps, -7.8 +/- 0.7 mmHg (P < 0.01 vs. vehicle); Lis, -23.8 +/- 1.8 mmHg; Aps + Lis, -37.5 +/- 1.9 mmHg (P < 0.01 vs. Lis). Aps did not affect the vasodepressor response to BK given into the descending aorta. Plasma BK increased only in Aps + Lis-treated rats (in pg/ml): control, 48.0 +/- 1.4; Lis, 57.5 +/- 7.6; Aps + Lis, 121. 8 +/- 30.6 (P < 0.05 vs. control or Lis), whereas in rats infused with BK (400 ng. kg-1. min-1 for 5 min), Aps increased plasma BK (in pg/ml): control, 51.9 +/- 2.5; Aps, 83.5 +/- 20.5; Lis, 725 +/- 225; Aps + Lis, 1,668 +/- 318 (P < 0.05, Aps vs. control and Lis vs. Aps + Lis). In rats with aortic coarctation hypertension, the acute antihypertensive effects of Aps plus Lis were greater than Lis alone (P < 0.01). Hoe-140, a BK B2-receptor antagonist, abolished the difference. We concluded that in the rat AMP contributes to regulation of BK metabolism and responses.  (+info)

Critical pathways for postoperative care after simple congenital heart surgery. (6/563)

OBJECTIVE: To evaluate the clinical, financial, and parent/patient satisfaction impact of critical pathways on the postoperative care of pediatric cardiothoracic patients with simple congenital heart lesions. STUDY DESIGN: Critical pathways were developed by pediatric intensive care nurses and implemented under the direction of pediatric cardiothoracic surgeons. PATIENTS AND METHODS: Critical pathways were used during a 12-month study on 46 postoperative patients with simple repair of atrial septal defect (ASD), coarctation of the aorta (CoA), and patent ductus arteriosus (PDA). Using the study criteria, a control group of 58 patients was chosen from 1993. Prospective and control group data collected included postoperative intubation time, total laboratory tests, arterial blood gas utilization, morphine utilization, time in the pediatric intensive care unit, total hospital stay, total hospital charges, total hospital cost, and complications. Variances from the critical pathway and satisfaction data were also recorded for study patients. RESULTS: Resource utilization was reduced after implementation of critical pathways. Significant reductions were seen in total hours in the pediatric intensive care unit, total number of laboratory tests, postoperative intubation times, arterial blood gas utilization, morphine utilization, length of hospitalization (ASD, 4.9 to 3.1 days; CoA, 5.2 to 3.2 days; and PDA, 4.1 to 1.4 days; all P < 0.05), total hospital charges (ASD, $16,633 to $13,627; CoA, $14,292 to $8319; and PDA, $8249 to $4216; all P < 0.05), and total hospital costs. There was no increase in respiratory complications or other complications. Patients and families were generally satisfied with their hospital experience, including analgesia and length of hospitalization. CONCLUSIONS: Implementation of critical pathways reduced resource utilization and costs after repair of three simple congenital heart lesions, without obvious complications or patient dissatisfaction.  (+info)

Stent implantation in an adult with coarctation of the aorta in the presence of advanced secondary heart failure. (7/563)

We report the case of a 56-year-old woman with congenital coarctation of the aorta, who presented in critical clinical condition with advanced secondary cardiomyopathy and heart failure. We successfully applied an unusual technique to pass the aortic obstruction, and then implanted a PALMAZ stent. The procedure resulted in prompt clinical improvement and completely resolved the coarctation. The patient's improved clinical condition was still evident 11 months after the procedure.  (+info)

Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. (8/563)

It has been proposed that the macula densa participates in the regulation of increased renin expression in renovascular hypertension (RVH) and that prostaglandins may be among the mediators of macula densa function. We have previously shown that in renal cortex, cyclooxygenase-2 (COX-2) expression is localized to the macula densa and surrounding cortical thick ascending limb and increases in high-renin states, such as salt restriction and angiotensin-converting enzyme inhibition. In the present studies, we examined the effect of the selective COX-2 inhibitor SC58236 on plasma renin activity (PRA) and renal renin expression in RVH in rats. The aorta was coarcted between right and left renal arteries, and animals received either SC58236 or vehicle for 1 week. At day 8, vehicle-treated coarcted rats were hypertensive (mean carotid arterial blood pressure: 138+/-3 versus 87+/-2 mm Hg in sham-operated controls; n=9 to 11; P<0.001) and exhibited a disparity of kidney size (ratio left/right kidney: 0.78+/-0.04 versus 1.02+/-0.02; n=9 to 10; P<0.001). PRA increased significantly (84.6+/-6.5 versus 9.0+/-1.4 ng angiotensin I [Ang I] per milliliter per hour; n=8 to 9; P<0.01). In the coarcted rats, neither renin mRNA expression nor renin activity of the right kidney was altered (renin/GAPDH mRNA: 1.12+/-0.05-fold levels in control rats; n=6; P=NS; renin activity: 23.4+/-1.8 versus 27.1+/-3.4 ng Ang I per hour per milligram protein; n=8 to 9; P=NS). However, the renin mRNA of the left kidney increased to 3.0+/-0.6-fold of control (n=6), and the renin activity increased to 189.0+/-28.6 ng Ang I per hour per milligram protein (n=8; P<0.01). Expression of COX-2 mRNA and immunoreactive protein increased in the affected left kidney but was not different from control in the unaffected right kidney. SC58236 treatment to coarcted rats did not affect kidney size (ratio left/right kidney: 0.79+/-0.06; n=9). However, PRA was significantly decreased compared with the vehicle-treated coarcted rats (19.8+/-2. 8 ng Ang I per milliliter per hour; n=9; P<0.01). The left kidney renin mRNA and renin content were also decreased (1.7+/-0.3-fold control; n=6; P<0.05; and 45.7+/-7.6 ng Ang I per hour per milligram protein; n=9; P<0.01, respectively), while renin mRNA and renin content of the right kidney were not altered. SC58236 lowered mean arterial blood pressure (122+/-5 mm Hg; n=14; P<0.05 compared with vehicle). A significant correlation was observed between PRA and mean blood pressure (r=0.75; P<0.01). In summary, these studies indicate that the selective COX-2 inhibitor SC58236 decreases renin production and release in RVH and suggest an important role for COX-2 regulation of the renin-angiotensin system.  (+info)

*Vascular myelopathy

However, TIAs can result from emboli in calcific aortic disease and aortic coarctation. Spinal arteriovenous malformations ( ... or aortic dissection (a tear in the aorta). Anterior spinal artery syndrome is necrosis of tissue in the anterior spinal artery ...

*Abdominal angina

Ingu A, Morikawa M, Fuse S, Abe T (2003). "Acute occlusion of a simple aortic coarctation presenting as abdominal angina". ... It can be associated with: carcinoid aortic coarctation antiphospholipid syndrome Internationally: Extremely rare. True ...

*George Karreman

In 1950 Karreman underwent experimental heart surgery for an aortic coarctation at the University of Chicago. He married Anneke ...

*Outline of cardiology

Cardiovascular causes of hypertension include coarctation of aorta, atherosclerosis, and aortic stenosis. Complications of ... Aortic valve replacement - Replacement of the aortic valve due to aortic regurgitation, aortic stenosis, or other reasons. A ... Aortic valve repair - Repair, instead of replacement, of the aortic valve. Aortic valvuloplasty - Repair of the valve by using ... Aortic valve - Disorders and treatments of the aortic valve that separates the left ventricle and aorta. Aortic regurgitation ...

*Clarence Crafoord

... best known for performing the first successful repair of aortic coarctation on 19 October 1944, one year before Robert E. Gross ... the first to repair aortic coarctation". Ann. Thorac. Surg. Netherlands. 87 (1): 342-6. doi:10.1016/j.athoracsur.2008.08.072. ...

*Crouzon syndrome

... is also associated with patent ductus arteriosus (PDA) and aortic coarctation. For reasons that are not ...

*Hyperdynamic precordium

It may also be due to aortic coarctation, and most other congenital heart malformations. Palpation of the chest wall can be ...

*Ventricular outflow tract obstruction

Aortic valve stenosis Supravalvar aortic stenosis Coarctation of the aorta Hypoplastic left heart syndrome Bashore TM (2007). " ... may be due to a defect in the aortic valve, or a defect located at the subvalvar or supravalvar level. ...

*Mechanobiology

"Differential progressive remodeling of coronary and cerebral arteries and arterioles in an aortic coarctation model of ...

*Endocardial fibroelastosis

Some of these hearts also had overt congenital anomalies, especially aortic stenosis and coarctation of the aorta. The term " ... "Early fetal endocardial fibroelastosis and critical aortic stenosis: a case report" Ultrasound Obstet Gynecol 5: 202-205. ...

*Stenosis

The term coarctation is another synonym, but is commonly used only in the context of aortic coarctation. Restenosis is the ... therefore causing narrowing Aortic valve stenosis, which is the thickening of the aortic valve, therefore causing narrowing ... "coarctation" at Dorland's Medical Dictionary Tracheal Stenosis Audio and Video. ...

*Ankle pressure

Bilateral decrease of ankle pressure can be seen e.g. in aortic disease, and in a young(ish) patient aortic coarctation should ...

*Dextro-Transposition of the great arteries

Left anterior thoracotomy Isolated pulmonary artery banding (PAB) Left lateral thoracotomy PAB (when coarctation or aortic arch ... It was Bex who introduced in 1980 the possibility of aortic translocation. But Nikaidoh has put the procedure in practice in ... which may also require a concomitant construction of an aortic-to-pulmonary artery shunt. When an arterial switch is impossible ...

*Congenital heart defect

Coarctation of the aorta (CoA) Double aortic arch, aberrant subclavian artery, and other malformations of the great arteries ... Common defects include pulmonic stenosis, aortic stenosis, and coarctation of the aorta, with other types such as bicuspid ... Aortic stenosis Atrial septal defect (ASD) Atrioventricular septal defect (AVSD) Bicuspid aortic valve Cardiomyopathy Complete ... For another member of the gene family, mutations in the Notch1 gene are associated with bicuspid aortic valve, a valve with two ...

*Cardiac surgery

Surgery on the great vessels (e.g., aortic coarctation repair, Blalock-Thomas-Taussig shunt creation, closure of patent ductus ...

*Notching of the ribs

Causes of inferior rib notching by etiology: Arterial: aortic coarctation, aortic thrombosis, pulmonary-oligemia/AV ... Inferior rib notching can be associated with aortic coarctation (as a result of dilatation of intercostal arteries), superior ... LearningRadiology.com > Coarctation Of the Aorta Retrieved August 2010 "Medcyclopaedia - Rib notching". Retrieved 2010-04-15. ...

*Pressure overload

Aortic stenosis Hypertension Coarctation of the aorta Pulmonary stenosis Pulmonary hypertension A forceful apex beat indicates ... Coarctation of the aorta presents with a significant difference in blood pressure between the upper and lower limbs. Treatment ... A narrow pulse pressure is a sign of aortic stenosis. The chest x-ray may show pulmonary hyperaemia in the case of pulmonary ...

*List of circulatory system conditions

Congenital heart defects Aortic coarctation (Aortic coarctation) Acyanotic heart defect Atrial septal defect Cor triatriatum ... Angina Acute coronary syndrome Anomic aphasia Aortic dissection Aortic regurgitation Aortic stenosis Apoplexy Apraxia ... Tricuspid atresia Interrupted aortic arch Coarctation of aorta Pulmonary atresia (PA) Pulmonary stenosis (critical) Atrial ... Vascular surgery Aortic aneurysm Saladin, Kenneth S.; Miller, Leslie (2004). "18". Anatomy & Physiology: The Unity of form and ...

*TBX2

... aortic coarctation, tricuspid valve insufficiency, and mitral valve stenosis. Contrary, those with Tbx2 gene deletion have ...

*PHACES Syndrome

... aortic coarctation and other aortic abnormalities Eye anomalies Sometimes an "S" is added to PHACE making the acronym PHACES; ... The association of posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac ...

*Acyanotic heart defect

Aortic stenosis Coarctation of the aorta Medications: Digoxin/Lanoxin Diuretics: Furosemide/Lasix Surgery Cyanotic heart defect ...

*List of MeSH codes (C16)

... aortic coarctation MeSH C16.131.240.400.145 --- arrhythmogenic right ventricular dysplasia MeSH C16.131.240.400.200 --- cor ...

*Cardiothoracic surgery

Surgery in great vessels (aortic coarctation repair, Blalock-Taussig shunt creation, closure of patent ductus arteriosus) ... Nazih Zuhdi, the Legendary Heart Surgeon, The Oklahoman, Jan 2010 Crafoord C, Nyhlin G. Congenital coarctation of the aorta and ... Once you're training for the speciality, you may choose to subspecialise in perhaps: aortic surgery; adult cardiac surgery; ... Aortic Surgery, Thoracic Surgery, Pediatric Cardiac Surgery or Cardiac ICU. Contemporary Canadian candidates completing general ...

*Turner syndrome

This includes bicuspid aortic valve and coarctation (narrowing) of the aorta. More than 50% of the cardiovascular malformations ... The prevalence of aortic root dilatation ranges from 8.8 to 42% in patients with Turner syndrome. Even if not every aortic root ... Aortic dissection affects 1 to 2% of patients with Turner syndrome. As a result, any aortic root dilatation should be seriously ... Cardiovascular malformations (typically bicuspid aortic valve, coarctation of the aorta, and some other left-sided cardiac ...

*List of MeSH codes (C14)

... aortic coarctation MeSH C14.240.400.145 --- arrhythmogenic right ventricular dysplasia MeSH C14.240.400.200 --- cor triatriatum ... aortic rupture MeSH C14.907.055.239 --- aortic aneurysm MeSH C14.907.055.239.075 --- aortic aneurysm, abdominal MeSH C14.907. ... aortic aneurysm, thoracic MeSH C14.907.109.139.175 --- aortic rupture MeSH C14.907.109.239 --- aortic arch syndromes MeSH ... aortic valve insufficiency MeSH C14.280.484.150 --- aortic valve stenosis MeSH C14.280.484.150.060 --- aortic stenosis, ...

*Secondary hypertension

C: Catecholamines, Coarctation of the Aorta, Cushing's Syndrome. *D: Drugs, Diet. *E: Erythropoietin, Endocrine Disorders [61] ... torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva ...
Figure 1: Enlarged MRA Pre and post stenting of coarctation. Perspective: Coarctation of the aorta is a relatively common defect that occurs in approximately 6-8 % of patients with congenital heart disease and is commonly associated with a bicuspid aortic valve. Intravascular stents are finding increased applications in the treatment of patients with native coarctation of the aorta and percutaneous intervention is a reasonable alternative to surgical correction. 4D flow MR imaging has shown promise in the evaluation of both the clinical significance of the coarctation through the demonstration of collateral blood flow and the persistence of helical flow after coarctation repair ...
Double orifice mitral valve is a rare congenital anomaly presenting as the division of the mitral orifice into two anatomically distinct orifices, it is most often associated with other congenital heart defects such as left-sided obstructive lesions, ventricular septal defects or aortic coarctation. We report the case of a 15 years old boy, admitted for arterial hypertension, auscultation revealed a rude aortic systolic murmur. Femoral pulses were weak. Owing to the suspicion of aortic coarctation, transthoracic echocardiography was performed, the aortic coarctation with dilation of the aorta proximal to the stenosis was confirmed and bicuspid aortic valve was found with good function. The mitral valve was dysmorphic, having two orifices; it was divided into 2 separate valve orifices by a fibrous bridge. No mitral or aortic regurgitation was documented by color Doppler flow imaging. The left ventricular ejection fraction was normal. There was a small peri membranous ventricular septal defect with left
TY - JOUR. T1 - Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload. AU - Yamashita, Yoshiyuki. AU - Tatewaki, Hideki. AU - Matsumoto, Takashi. AU - Shiose, Akira. PY - 2018/10/1. Y1 - 2018/10/1. N2 - A 13-year-old girl, who had undergone interrupted aortic arch repair with an 8-mm graft as a neonate and Fontan completion in childhood, developed ventricular fibrillation due to long-QT syndrome. Cardioverter defibrillator implantation was planned. Preoperative catheterization showed a 45-mmHg aortic pressure gradient and ventricular end-diastolic pressure of 11 mmHg. This indicated that recurrent coarctation had adversely affected ventricular function. After consideration of the patients age, symptoms and anatomical/surgical complexities, axillo-iliac bypass with cardioverter defibrillator implantation was performed. Postoperative ventricular end-diastolic pressure was 6 mmHg. Axillo-iliac bypass is a surgical option for coarctation that can reduce cardiac ...
Pressure and flow were recorded in the ascending aorta of three dogs with aortic coarctation, induced surgically 3 months previously, and in three control litter mates. From these data were derived input impedance of the systemic circulation, pulsatile and steady components of external heart work, aortic systolic pressure-time index, and mean systolic and mean diastolic pressures. Results were correlated with intraoperative measurements of aortic pressure in three young patients with aortic coarctation and with records taken in another 24 patients during diagnostic catheterization. Distinctive changes in aortic impedance with coarctation were explained in terms of altered peripheral reflection. Such changes were responsible for characteristic alteration in central aortic pressure pulse contour and for change in other parameters, indicating impaired arterial function in accepting pulsatile flow from the heart. Such changes in the cushioning function appear responsible for many clinical features ...
TY - JOUR. T1 - Management of arch hypoplasia after successful coarctation repair. AU - DeLeon, Maryann M.. AU - DeLeon, Serafin Y.. AU - Quinones, Jose A.. AU - Roughneen, Patrick. AU - Magliato, Kathy E.. AU - Vitullo, Dolores A.. AU - Cetta, Frank. AU - Bell, Timothy J.. AU - Fisher, Elizabeth A.. PY - 1997. Y1 - 1997. N2 - Background. Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a somewhat hypoplastic arch to grow or from clamp injury at the time of the initial repair, or from both causes. Because of mediastinal adhesions and minimal collateral circulation, use of extraanatomic bypass grafts appears to be the preferred approach. Methods. Six children or young adults presented with arch obstruction over a 3-year period. Their mean age was 13.5 ± 4 years, and the mean interval from the time of the initial repair was 10 ± 4 years. The mean age of the patients at the time of the initial repair was 3.2 ± 5 years. ...
TY - JOUR. T1 - Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta. T2 - An observational study by the CCISC (Congenital cardiovascular interventional study consortium). AU - Forbes, Thomas J.. AU - Kim, Dennis W.. AU - Du, Wei. AU - Turner, Daniel R.. AU - Holzer, Ralf. AU - Amin, Zahid. AU - Hijazi, Ziyad. AU - Ghasemi, Abdolrahim. AU - Rome, Jonathan J.. AU - Nykanen, David. AU - Zahn, Evan. AU - Cowley, Collin. AU - Hoyer, Mark. AU - Waight, David. AU - Gruenstein, Daniel. AU - Javois, Alex. AU - Foerster, Susan. AU - Kreutzer, Jacqueline. AU - Sullivan, Nancy. AU - Khan, Asra. AU - Owada, Carl. AU - Hagler, Donald. AU - Lim, Scott. AU - Canter, Joshua. AU - Zellers, Thomas. PY - 2011/12/13. Y1 - 2011/12/13. N2 - Objectives: The purpose of this study was to compare the safety and efficacy of surgical, stent, and balloon angioplasty (BA) treatment of native coarctation acutely and at follow-up. Background: Controversy surrounds the optimal ...
Arterial hypertension remains a common problem after coarctation repair, and is a major concern in the long-term outcome of these patients. The pathophysiology of hypertension after successful surgical treatment of aortic coarctation, and in the absence of re-coarctation is still poorly understood. It has been suggested that coarctation of the aorta could represent a primary or secondary systemic vasculopathy rather than an isolated local disease of the aortic isthmus. These changes are thought to be involved in the development of hypertension in the absence of re-coarctation as well as premature cardiovascular events.. A number of observational studies in patients after coarctation repair have proposed endothelial dysfunction as measured by FMD, or a decreased reactivity to nitric oxide of the arterial wall as a key player in this respect.3 ,19-22 Impairment of FMD in these patients has been described with20 and without evidence of increased blood pressures.3 This has lead to the hypothesis ...
Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. The word "coarctation" means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with coarctations. Other heart defects may also occur when coarctation is present, typically occurring on the left side of the heart. When a patient has a coarctation, the left ventricle has to work harder. Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood through the aorta to deliver blood to the lower part of the body. If the narrowing is severe enough, the left ventricle may not be strong enough to push blood through the coarctation, thus resulting in lack of blood to the lower half of the body. Physiologically its complete form is manifested as interrupted aortic arch.[citation ...
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The long-term outlook for children who have had their coarctation repaired, either with surgery or angioplasty, is excellent. Children who have successful repair of coarctation usually can live full and productive lives. Women usually can become pregnant safely. However, medical problems can occur after repair.. Recoarctation. Recoarctation is the redevelopment of a narrowing in the aorta. This problem occurs more commonly in children who have had their coarctation repaired during the first year of life. Recoarctation occurs in approximately 10% to 20% of children who have had their repair in infancy, and in less than 3% of children who have had their repair after 3 years of age. Treatment of recoarctation of the aorta usually is with a balloon angioplasty.. High blood pressure. High blood pressure is one of the most common medical problems seen in patients after successful repair of coarctation. Approximately 60% of people who have had their coarctation repaired will require medication to treat ...
TY - JOUR. T1 - Coarctation of the aorta. T2 - Lifelong surveillance is mandatory following surgical repair. AU - Brown, Morgan L.. AU - Burkhart, Harold M.. AU - Connolly, Heidi M.. AU - Dearani, Joseph A.. AU - Cetta, Frank. AU - Li, Zhuo. AU - Oliver, William C.. AU - Warnes, Carole A.. AU - Schaff, Hartzell V. PY - 2013/9/10. Y1 - 2013/9/10. N2 - Objectives The objective of our study was to review the long-term outcomes of patients undergoing surgical repair of aortic coarctation. Background Surgical repair of aortic coarctation has been performed at the Mayo Clinic, Rochester, Minnesota, for over 60 years. Methods Between 1946 and 2005, 819 patients with isolated coarctation of the aorta underwent primary operative repair. Medical records were reviewed and questionnaires mailed to the patients. Results Mean age at repair was 17.2 ± 13.6 years. The majority (83%) had pre-operative hypertension. Operations included simple and extended end-to-end anastomosis (n = 632), patch angioplasty (n = ...
Children beyond infancy are usually asymptomatic and are most often diagnosed because of a murmur or hypertension on a routine examination[1]. Delayed or absent femoral pulses and an arm/leg systolic blood pressure difference of 20 mm Hg or more in favor of the arms may be considered as evidence for aortic coarctation[3].. The coarctation can be demonstrated on suprasternal notch two-dimensional echocardiographic views along with increased Doppler flow velocity across the coarctation site[1]. Cardiac catheterization reveals significant systolic pressure gradient (, 20 mm Hg) across the coarctation and angiography demonstrates the degree and type of aortic narrowing[3].. Surgical relief of coarctation may be achieved by resection and end-to-end anastomosis or by subclavian flap or prosthetic path angioplasty[1]. Elective repair of isolated aortic coarctation is nowadays indicated at 3-6 months of life or at the time of diagnosis[2]. Complications, such as recoarctation or secondary hypertension, ...
To the Editor:. Using percutaneous catheter techniques and endovascular grafts, Ince et al1 reported successful treatment of aneurysms occurring after previous repair of aortic coarctation with no mortality and minimal morbidity in 6 patients. They contrasted these results with those reported for similar patients with open surgical treatment, in whom the mortality rates ranged between 14% and 23.5%. The 3 references reporting these outcomes were published between 1989 and 1996.. Any comparison of these 2 methods of treatment for recurrent aneurysm after coarctation repair should include contemporary reports that use modern surgical techniques. Two recent studies using the technique of full cardiopulmonary bypass and circulatory arrest in 9 patients with complications following surgical repair of aortic coarctation (including 7 patients with aneurysms or pseudoaneurysms) reported no early deaths and few major complications.2,3. Although minimally invasive endovascular techniques offer important ...
The patient was a 19 year-old woman with the diagnosis of resistant hypertension, although she was under treatment of three classes of anti-hypertensive drugs (beta blocker, angiotensin receptor blocker, diuretic) for more than one year. In physical examination there was only a significant difference between the systolic blood pressure of upper and lower extremities (200 vs. 120 mmHg), without any other remarkable finding. Three different imaging modalities (echocardiography (Figure 1), CT angiography (Figure 2), conventional aortography (Figure 3) confirmed the aortic coarctation at 30 mm after left subclavian artery origin, with the 3.5-4 mm diameter of the narrowest segment. She underwent implantation of a self-expanding aortic stent and therefore the systolic pressure gradient decreased from 90 to 15 mmHg. After three months, her blood pressure was stable on 110/80 mmHg, while she received only metoprolol 25 mg twice daily and follow-up echocardiography showed 15-20 mmHg pressure gradient through
Background. Dacron patch aortoplasty repair of coaretation of the aorta carries an inherent risk of aneurysm development. Sudden death from aortic rupture prompted discontinuing this operation and evaluating 39 patients (16 girls; mean age 6.3 years, range 10 days to 14.5 years) undergoing repair between January 1976 and October 1987. The aorta ruptured in 10 patients; 6 died at a mean interval of 8.1 years (range 0.75 to 12.4) after repair. All 33 survivors were interviewed and examined. ...
Peak ascending and descending aortic blood flow velocities were measured using continuous wave Doppler ultrasound velocimetry in 30 children with coarctation or recoarctation of the aorta and in 13 control subjects. The results were compared with the arm to leg systolic blood pressure difference. The peak flow velocities in the descending aorta were significantly higher in the patients than in the control subjects and there was a close correlation with the systolic blood pressure gradient. Since there was no overlap of flow velocities between the patients and the control subjects the Doppler technique enables coarctation confidently to be excluded as well as demonstrating its presence and severity. The method is simple, rapid, independent of the condition of the aortic valve, and is applicable to neonates in whom the diagnosis of coarctation may otherwise be difficult. In older children it is useful for detecting recoarctation and following its progress, particularly in patients in whom a ...
Hypoplastic infrarenal aorta or infrarenal aortic coarctation is an uncommon vascular pathology characterized with diffuse stenosis in the infrarenal abdominal aorta. It is a variant of atherosclerotic occlusive diseases. The exact incidence and etio
To assess the effects on the biosynthesis of collagen types I and III associated with an acute increase in blood pressure, we established a mid-thoracic aortic coarctation in the rabbit and studied gene expression and protein accumulation of these collagen types proximal to the stenosis 1, 3 and 7...
Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at JFK Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at Grand Strand Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at TriStar Centennial Parthenon Pavilion DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
In this report 5 patients between the ages of 5-14 years admitted to the Department of Pediatric Cardiology, Hacettepe University, and diagnosed as having pseudocoarctation of the aorta arc presented. The clinical and angiographic findings of this rare abnormality of childhood are discussed, the importance of differential diagnosis of this entity from coarctation of the aorta is emphasized, and the literature reviewed. © 1990, International Heart Journal Association. All rights reserved ...
TY - JOUR. T1 - Impact of treatment modality on vascular function in coarctation of the aorta. T2 - The LOVE-COARCT study. AU - LOVE-COARCT Study. AU - Martins, José D.. AU - Zachariah, Justin. AU - Tierney, Elif Seda Selamet. AU - Truong, Uyen. AU - Morris, Shaine A.. AU - Kutty, Shelby. AU - de Ferranti, Sarah D.. AU - Guarino, Maria. AU - Thomas, Boban. AU - Oliveira, Diana. AU - Marinho, António. AU - António, Marta. AU - Gauvreau, Kimberlee. AU - Jalles, Nuno. AU - Geva, Tal. AU - Carmo, Miguel M.. AU - Prakash, Ashwin. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Background-Optimally treated patients with coarctation of the aorta remain at risk for late vascular dysfunction. The effect of treatment modality on vascular function is unknown. The LOVE-COARCT (Long-term Outcomes and Vascular Evaluation After Successful Coarctation of the Aorta Treatment) study was done to compare vascular function in patients with coarctation of the aorta treated with surgery, balloon dilation (BD), or stent ...
Catheter Cardiovasc Interv. 2014 Jun 1;83(7):1124-30. doi: 10.1002/ccd.25318. Epub 2014 Jan 6. Research Support, Non-U.S. Govt
Coarctation of the aorta (CoA) is a congenital abnormality producing obstruction to blood flow through the aorta. Coarctation can occur in isolation, in association with bicuspid aortic valve or with major cardiac malformations. CoA accounts for 5-8% of the 8/1000 (4-6/10,000) children born with congenital heart disease. Most CoA is newly diagnosed in childhood; , 25% recognized beyond 10 yrs.. CoA is mostly repaired in childhood by surgery or by balloon catheter dilation. Recurrence rates range from 5-20%. Recurrence is often not recognized until adolescence. Balloon expandable stents have become the predominant therapy in the USA and Europe for CoA treatment in this age group. There are no FDA approved stents for this use. Biliary stents are currently being used off label. Enrollment into a trial of bare metal Cheatham Platinum (CP) Stents, designed for use in CoA, is completed. The Coarctation of the Aorta Stent Trial (COAST) aims to confirm safety and efficacy of CP Stent for native and ...
Coarctation of the aorta: Find the most comprehensive real-world symptom and treatment data on coarctation of the aorta at PatientsLikeMe. 13 patients with coarctation of the aorta experience fatigue, depressed mood, pain, anxious mood, and insomnia.
Coarctation of the aorta is a common heart defect present at birth.. With this defect, a portion of the large blood vessel that carries blood from the heart to the rest of the body (aorta) is abnormally narrowed or pinched. Coarctation of the aorta makes it harder for the heart to pump blood to the body. Over time, this can lead to high blood pressure, heart failure, or other complications.. This condition is usually detected in newborns during normal blood pressure checks and by listening to the heart. Further tests, such as echocardiography, may be done to confirm the diagnosis.. Coarctation of the aorta requires repair by surgery or heart catheterization.. ...
Causes of Coarctation of aorta dominant including triggers, hidden medical causes of Coarctation of aorta dominant, risk factors, and what causes Coarctation of aorta dominant.
Coarctation of the aorta is a common congenital cardiovascular defect characterized by upper-body hypertension resulting from constriction of the aorta. Constrictions vary in degree; they may occur at any point from the transverse arch to the iliac bifurcation.
The long-term outlook for children who have had their coarctation repaired, either with surgery or angioplasty, is excellent. Children who have successful repair of coarctation usually can live full and productive lives. Women usually can become pregnant safely. However, medical problems can occur after repair.. Recoarctation. Recoarctation is the redevelopment of a narrowing in the aorta. This problem occurs more commonly in children who have had their coarctation repaired during the first year of life. Recoarctation occurs in approximately 10% to 20% of children who have had their repair in infancy, and in less than 3% of children who have had their repair after 3 years of age. Treatment of recoarctation of the aorta usually is with a balloon angioplasty.. High blood pressure. High blood pressure is one of the most common medical problems seen in patients after successful repair of coarctation. Approximately 60% of people who have had their coarctation repaired will require medication to treat ...
Evidence-based recommendations on balloon angioplasty with or without stenting for coarctation (narrowing) or recoarctation of the aorta
Coarctation of the aorta (CoA) accounts for 8%-11% of congenital heart defects, affecting tens of thousands of patients annually in the western world. Surgical or catheter-based treatments seek to alleviate the blood pressure gradient through the coarctation in order to reduce the workload on the heart. The pressure gradient is dependent on the anatomic severity of the coarctation: the greater the % of area reduction, the larger the pressure gradient. Furthermore, the pressure gradient is also greatly dependent on the flow rate and therefore the physiologic state of the patient: a small pressure gradient at rest can increase several-fold even in mild exercise conditions. The clinician can easily measure the pressure gradient through the coarctation under resting conditions, either by using a catheter-driven pressure transducer or a sphygmometer. However, measuring the pressure gradient under exercise conditions is more challenging since these conditions are not easy to replicate in the clinic. ...
To evaluate ventricular performance and myocardial contractility after surgical correction of congenital coarctation of the aorta, we studied 25 patients (16 men and 9 women, mean age 26.1 years [range 19 to 34]), an average of 10.6 years (range 2 to 25) after repair. Radionuclide ventriculography at rest and exercise and digitized, quantitative two-dimensional echocardiography were performed. Data from derived, high resolution time-activity curves by radionuclide ventriculography, combined with noninvasive hemodynamic/ven-tricular volume data, were compared with values in an age- and sex-matched normal population.. Despite essentially identical baseline and exercise hemodynamics, postoperative coarctation subjects demonstrated enhanced ventricular contraction, as determined by the peak ejection rate at rest (−3.79 versus −3.20 stroke volume/s, p , 0.01) and exercise (−3.00 versus −2.90 stroke volume/s, p = NS), and overall ejection fraction at rest (56.4 versus 48.0%, p , 0.01) and ...
OBJECTIVE: The placement of a modified Blalock-Taussig shunt in patients suffering from pulmonary coarctation can result in the aggravation of uneven pulmonary blood flow. This may subsequently obviate the possibility of future performance of the Fontan procedure. The objective of this study was to evaluate mid-term results in patients with pulmonary coarctation who had undergone the placement of a modified Blalock-Taussig shunt, coupled with a pulmonary artery angioplasty. METHODS: We retrospectively reviewed the records of 13 patients who had undergone the placement of a modified Blalock-Taussig shunt, coupled with concomitant pulmonary angioplasty, between September 1998 and August 2002. All patients received follow-up angiographic evaluations. RESULTS: On the ipsilateral side of the modified Blalock-Taussig shunt, we observed a significant increase in the pulmonary artery index during a mean follow-up period of 11+/-5 months (preoperative 82+/-37 mm2/m2, follow-up 129+/-57, p=0.03). On the ...
We describe a case of aortic coarctation at the level of the infrarenal abdominal aorta which is encountered in less than six individuals in one million. In contrast to aortic narrowing above or including the renal arteries, this seems to be a relatively benign anomaly without systemic hypertension or impaired renal function. For the first time in this type of anomaly, contrast-enhanced MR angiography (ce-MRA) on a multi-receiver channel MR system, with an 8-channel phased array coil and parallel imaging was used. Ce-MRA displayed a tortuous, narrowed aortic segment that was found to be associated with mesenteric artery stenosis and compression of the orthotopic left renal vein, also known as the nutcracker phenomenon. All major aortic branches could be depicted using 3D surface-shaded displays and subvolume maximum intensity projections (MIPs). Collateral vessels of the abdominal wall were identified using whole-volume MIPs. Since the majority of aortic malformations are diagnosed at a younger age, and
It has been estimated that 20 -30% of repaired aortic coarctation (CoA) patients develop hypertension, with significant cardiovascular morbidity and mortality. Vertebral artery hypoplasia (VAH) with an incomple......
Aortic coarctation is a narrowing of a portion of the aorta, the major artery that leads out of the heart to the body. This narrowing usually occurs at ...
Aortic coarctation can be difficult to identify on chest x-ray and routine review of aortic outline, as well as the ribs, is necessary if one is to make the diagnosis.
The aim of this study was to explore the clinical impact of transverse aortic arch hypoplasia (TAH) after stent implementation for isthmal coarctation of the aorta (CoA). From a retrospective chart...
In six inbred dogs with neonatally-induced coarctation hypertension, and in seven littermate controls, acute responses of proximal arterial pressure and plasma renin activity (PRA) to converting enzyme inhibitor (CEI; SQ 20,881, 0.5 mg/kg i.v.) were serially examined. Studies were performed at 2, 6, and 12 months post-aortic banding under sodium-replete and -deplete conditions. Both in normotensive controls and in coarcted dogs, depressor responses (pre- minus post-CEI values) were positively correlated, not only with initial (pre-CEI) PRA, but also independently with initial blood pressure. Although absolute depressor responses in coarcted dogs exceeded those of the control group, there were no significant group differences when, by analysis of covariance, depressor responses were adjusted for the physiologic influence of initial pressure. Similarly, depressor responses expressed as a percent of initial pressure were comparable in coarcted and control groups. Initial PRA and PRA response to CEI ...
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Coarctation of the aorta is a narrowing of the descending aorta, which is typically located at the insertion of the ductus arteriosus just distal to the left subclavian artery (). This defect generally results in left ventricular pressure overload.Th
Background:. Coarctation of the aorta (CoA) is a congenital heart disease which represents a narrowing of the proximal descending aorta, hence increasing pressure afterload to the left ventricle (LV). Conventional treatment of native CoA is surgical repair, however potential recurrence or other related complications e.g. aortic rupture, heart failure and cerebrovascular events are common. Thus, lifelong follow-up of these patients is required. Echocardiography is the most patients friendly method to evaluate CoA and in particular its effect on LV function. Moreover, the novel speckle tracking echocardiography (STE) is an important method to assess subclinical LV dysfunction, a technique that promises better evaluation of LV function in these patients.. The aims of this thesis were to review the literature on LV function in children with CoA using myocardial deformation imaging technologies, hence, to better understand the current knowledge and vagueness of the scientific evidence. We also aimed ...
hello, i want to know what average life expentancy is for some one who has coarctation of the aorta, repaired as young child, age 5, with bicuspid valve, will probably need replacing in 10 yrs time, am...
Coarctation of the aorta is a heart defect that is present at birth (congenital). It means the aorta is narrower than it should be. Read on to learn details about the condition.
Nemours pediatric heart experts specialize in early detection and repair of congenital heart defects such as coarctation of the aorta.
Coarctation of the aorta is a narrowing of the aorta. It can lead to worsening heart function over time, but effective treatments are available.
... occurs when the aorta narrows, causing blood flow restriction. Taking Zofran while pregnant increases the risk of COA.
The gradient across coarctation is not simply (& solely ) determined by degree of obstruction , as one would believe.Understanding the hemodynamics and various factors that can influence the gradient is essential Relieving the obstruction /gradient by stent or surgery may not be synonymous with successful treatment as we understand now the entire aorta right…
Coarctation of the aorta (COA) is a narrowing of the aorta, the major blood vessel that carries blood away from the heart to the body.
When someone has coarctation of the aorta, that persons aorta (the major blood vessel that carries blood away from the heart to the body) is narrowed at some point.
When someone has coarctation of the aorta, that persons aorta (the major blood vessel that carries blood away from the heart to the body) is narrowed at some point.
Coarctation of the aorta(COA) is a narrowing of the major artery that carries blood to the body. Learn why we are the best place for your childs care.
A new approach for the evaluation of the severity of coarctation of the aorta using Doppler velocity index and effective orifice area: In vitro validation and clinical implications Academic Article ...
The volume of literature concerning dissecting aneurysm of the aorta has become so great since Shennans monograph in 19341 that only an unusual case seems to warrant recording. In the one to be presented, a coarctation developed following a "double barreled" transformation of the aorta from its ring to bifurcation. ...
Learn more about the possible symptoms of coarctation of the aorta, including hypertension, chest pain, claudication, and headaches.
We need to stay vigilant for the needles in the haystack of pediatric illnesses. One of those needles is Coarctation of the Aorta.
ANEMIA and COARCTATION OF AORTA related symptoms, diseases, and genetic alterations. Get the complete information with our medical search engine for p
I read an article saying that people with a repaired coarctation of aorta will only live max for 20 years after repair is this true?
The "Blood Pressure Gradient" of the entire systemic circulation is simply the systemic arterial pressure minus the right atrial pressure. Since the pressure in the right atrium is small or nearly zero we can largely ignore this variable. Consequently, the "Blood Pressure Gradient" can simply be replaced by the "Systemic Arterial Pressure". The "Blood Flow Volume" of the entire systemic circulation is simply the cardiac output of the heart. The "Resistance" of the entire systemic circulation is simply the systemic vascular resistance ...
Atherosclerotic plaques are distributed differently in the aortic arches of C57BL/6 (B6) and 129/SvEv (129) apolipoprotein E (apoE)-deficient mice. It is now recognized that hemodynamic wall shear stress (WSS) plays an important role in the localization of atherosclerotic development. Since the blood flow field in the vessel is modulated by the vascular geometry, we quantitatively examined the difference in the aortic arch geometry and hemodynamic WSS between the two corresponding wild-type mouse strains. The three-dimensional (3D) geometry of 14 murine aortic arches, seven from each strain, was characterized using casts and stereo microscopic imaging. Based on the geometry of each cast, an average 3D geometry of the aortic arch for each mouse strain was obtained, and computational fluid dynamic calculations were performed in the two average aortic arches. Many geometric features, including aortic arch shape, vessel diameter, and branch locations, were significantly different at ...
A congenital vascular abnormality that affects the great vessels and/or aortic arch. Representative examples include double aortic arch, aortic coarctation, and absence of a pulmonary artery.
The leamer should be able to improve technical perfonmance of echocardiograms in congenital heart disease. They should be able to further their understanding of complex physiology and the appropriate questions to answer with the study. In addition, emphasis is placed on medical andlor surgical management as well as further studies (cardiac catheterization, cardiac magnetic resonance imaging or computed tomography scan) that may be needed. Information to be obtained on followup echocardiograms will also be reviewed.. These sessions are designed to improve the technical performance and interpretation of echocardiograms in complex congenital and acquired heart disease. Case studies are presented, followed by discussion of new noninvasive methods of evaluation and medical and/or surgical management options. All attendees are invited to participate in the discussion. ...
Hi. I am a 40 year old woman, 5 5, 108 lbs. I have many medical problems and have difficulty with fatigue and weakness. I have a disease called Klippel Trenaunay Syndrome. I have extensive AVMs i...
Learn more about the causes and treatment of this usually congenital heart condition that is treatable but requires lifelong follow-up.
The same info as provided by GPs to patients during consultations,health/disease leaflets,all about medicines,book GP appts online,interactive patient experience forum
Definition : Vascular surgical clamps designed for the atraumatic compression of the aorta during open-surgery procedures (e.g., resection, graft placement, coronary artery bypass, cardiac valve replacement/repair), usually to cause total or partial temporary occlusion (i.e., coarctation). These clamps are typically handheld, manual instruments including two parts pivoted at the center with serrated, straight, or curved distal blades and a ratchet-locking mechanism. The serrated region frequently has a central, nonserrated trough running its length to prevent trauma to the aorta.. Entry Terms : "Clamps, Aorta" , "Aorta Clamps, Surgical". UMDC code : 10864 ...
Definition : Vascular surgical clamps designed for the atraumatic compression of an artery during open-surgery procedures, usually to cause total or partial temporary occlusion (i.e., coarctation). These clamps are typically handheld, manual instruments including two parts pivoted at the center with serrated, straight, or curved distal blades, and a ratchet-locking mechanism. The serrated region frequently has a central, nonserrated trough running its length to prevent trauma to the enclosed artery. Dedicated artery clamps are available for specific arteries (e.g., aorta, carotid, pulmonary) and/or procedures (e.g., anastomosis).. Entry Terms : "Clamps, Artery" , "Artery Clamps, Surgical". UMDC code : 10865 ...
Myocardial hyperfunction is experimentally modeled by coarctation of the aorta in mature (6-8-month-old) and senescent (26-28-month-old) Wistar rats. During the emergency phase of cardiac...
Eli is my miracle of God. There is no other way to look at it. I am ashamed to admit some things and this may anger some, but I feel I have to tell this WHOLE story as I believe it shows that God works in mysterous ways. Its no secret that I have always wanted a girl. So back when I first found out Eli was a boy, I was really disappointed. I thought he was my last baby and therefore my last chance for a girl. I didnt understand all that He had planned. If I had really been paying attention and kept my focus on God I would have seen. However, I also know that part of Gods plan was my disappointment. You see after I found out he was a boy the doctor put me on anti-anxiety medication. That medication is linked to heart problems, specifically abnormal pressures in the heart. It was this abnormal pressure that God used to SAVE Eli from leaving me. He knew it, but I didnt. After Eli was born we didnt know he had a heart problem. He was actually born with three heart problems: a coarctation of the ...
An efficient method for the formal anti-Markovnikov hydration of 1,1-disubstituted alkenes has been developed. The utility of the process has been demonstrated by conversion of bio-derived butene oligomers into primary alcohols through initial oxidation to vicinal acetoxy-alcohols, diols, or diacetates, foll
Looking for online definition of aortic coarctation in the Medical Dictionary? aortic coarctation explanation free. What is aortic coarctation? Meaning of aortic coarctation medical term. What does aortic coarctation mean?
Looking for online definition of coarctation of the aorta in the Medical Dictionary? coarctation of the aorta explanation free. What is coarctation of the aorta? Meaning of coarctation of the aorta medical term. What does coarctation of the aorta mean?
The case of a 25-year-old woman with coarctation of the thoracic aorta and combined bilateral fibromuscular dysplasia of the renal arteries is reported. Although marked hemodynamic changes induced by the coarctation were probably pre-existent, hypertension was revealed only during the last month of her first pregnancy and was spontaneously corrected 2 months post partum. Surgical treatment of the thoracic coarctation did not influence blood pressure which remained normal ...
TY - JOUR. T1 - Long-term Follow-up of "Simple" Lesions-Atrial Septal Defect, Ventricular Septal Defect, and Coarctation of the Aorta. AU - Goldberg, Jason. PY - 2015/9/1. Y1 - 2015/9/1. N2 - Surgery for congenital heart disease has advanced significantly in the past 50 years, such that repair of "simple" lesions, such as atrial septal defect, ventricular septal defect, and coarctation of the aorta carries minimal risk, with mortality risk much less than 1%. It was once thought successful repair of these lesions was definitively corrective. There is mounting evidence, however, that there are long-term complications after these repairs, prompting the need for continued follow-up. This review describes the current understanding of diagnosis, treatment, and long-term outcomes for these patients, with the goal of advocating for lifelong surveillance. As the perioperative care of these repairs has evolved significantly over time, so must the way in which we study these patients in the ...
Bicuspid aortic valves (BAVs) represent a wide morphologic and functional spectrum. In coarctation of the aorta, BAVs are common, but the proportion of BAV subtypes and their relation to aortic dimensions and development of late valve dysfunction are unknown. Sixty-two cardiovascular magnetic resonance investigations of patients with coarctation of the aorta were reviewed with respect to aortic valve morphology, aortic valve function, and aortic dimensions. BAVs were identified in 45 patients (72.6 %), of which 13 (20.9 %) were type-0 (two commissures), 28 (45.1 %) type-1 (three commissures but fusion of one commissure with a raphe) and 4 (6.5 %) valves were bicuspid but not possible to classify further. Patients with BAVs type-0 had larger dimensions in their sinus of Valsalva (35.5 ± 6.8 vs. 29.7 ± 2.7 mm, p = 0.002), ascending aorta (33.1 ± 6.2 vs. 26.0 ± 4.3 mm, p = 0.005) and sino-tubular junction (29.3 ± 7.4 vs. 24.2 ± 3.5 mm, p = 0.040) compared with tricuspid aortic valves (TAVs). ...
This is the official website of Razi Journal of Medical Sciences published by Tehran University of Medical Sciences.The Razi Journal of Medical Sciences (RJMS) is the scientific medical journal of Iran, which has been published from 1993 onward in Persian with abstract of English language (former Journal of Iran University of Medical Sciences). Although it had been published quarterly in the past, RJMS has been published monthly (12 issues per year) from the year 2009. The Razi Journal of Medical Sciences, a scientific and research peer reviewed journal, seeks to publish original papers, selected review articles and case reports. RJMS also seeks to provide its readers with the highest quality materials published through a process of careful double-blind peer reviews and editorial comments. RJMS is an official publication of the Tehran University of Medical Sciences.
Coarctation of the aorta is a congenital defect affecting blood flow from the heart. Learn more from Boston Childrens Hospital.
The U.S. Food and Drug Administration (FDA) recently approved the NuMED Cheatham Platinum (CP) Stent System for the prevention and/or treatment of aortic wall injury (AWI) in patients with coarctation of the aorta involving a compliant aortic isthmus or first segment of the descending aorta where there is adequate size and patency of at least one femoral artery and balloon angioplasty is contraindicated or predicted to be ineffective.. Stent therapy for coarctation of the aorta offers a non-surgical alternative to traditional operative repair of the aortic obstruction with similar results and complication rates. Stent treatment also has a lower rate of recurrence and aortic wall injury compared to balloon dilation alone.. Covered stent therapy provides similar outcomes and allows for simultaneous treatment of aortic wall injuries, such as aneurysm and pseudo-aneurysm that might be present, related to previous surgical or catheter based therapy of the coarctation. In the COAST II clinical trial, ...
Assess ventricular function, volumes and LV mass (may be increased 2° LVOTO or hypertension). Measure peak CoA velocity, look for diastolic prolongation of forward flow Fig. 1. Contrast-enhanced axial CT showing a transverse fracture through the mid-portion of a coarctation stent. There is a residual moderate coarctation, and marked dilatation of the descending thoracic aorta Fig. 2. Volume rendered 3D reconstruction of a contrast-enhanced CT angiogram showing a coarctation stent with mild residual narrowing (arrow). A) b-SSFP image oblique coronal view, showing narrow jet of moderate aortic regurgitation. (b) b-SSFP images showing a 4-Ch view of a dilated left ventricle in a patient with aortic regurgitation 18 a Aortic Valve Incompetence c 500 Normal Mild AR Moderate AR 400 Severe AR b Flow volume (mL/s) 300 200 100 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 -100 Time frames -200 Fig. 2. Aortic regurgitation phase contrast velocity mapping, (a) magnitude image aortic valve, (b) phase contrast ...
1) Short stature. 2) Web neck ( Extra folds of skin on the neck). 3) Low hairline at the back of the neck. 4) Low-set ears. 5) Infections of the middle ear (otitis media) usually in infants. There is a documented relationship between Turner syndrome and sensorineural hearing loss in adults.. 6) Puffiness or swelling (lymphedema) of the neck, hands and feet.. 7) Broad shield shaped thorax and widely spaced nipples.. 8) Poor breast development. 9) Skeletal abnormalities including cubitus valgus (elbow deformity), scoliosis, short 4th metacarpal. 10) Narrow fingernails and toenails that are turned upward.. 11) Primary amenorrhea.. 12) Infantile external genitalia. 13) Ovaries severely atrophied and fibrous (streak ovaries). 14) Congenital heart disease, particularly aortic coarctation (narrowing of the large artery). 15) The incidence of aortic dissection is extremely common and occurs early in life and in pregnancy. 16) Skin changes, including an increased number of melanocytic nevi, hypertrophic ...
To investigate the relation of pressure and vascular wall thickening in hypertension, we coarcted the abdominal aorta upstream to the renal arteries in 14 rats. Sham-coarcted (n = 16) and two-kidney, one-clip (Goldblatt) hypertensive rats (n = 13) served as controls. Tail, femoral, and carotid arterial pressures rose (p less than 0.01) in the two-kidney, one-clip hypertensives; only carotid pressure rose (p less than 0.01) in the coarcted rats, tail and femoral pressures remaining normal (p greater than 0.25). Thus, the hindquarters of the coarcted rats remained normotensive. Four to six weeks after surgery we perfusion-fixed vascular tissues of the hindquarters, including kidneys, with formalin at in vivo levels of pressure. Glycol methacrylate-embedded tissues were sectioned at 1 micron thickness and vessels quantitatively evaluated. The outer medial and lumen perimeters of abdominal aorta, femoral artery, and renal arterioles were measured; from these measurements, vessel outer and lumen ...
Anatomic aortic anomalies are seen in many medical conditions and are known to cause disturbances in blood flow. Turner syndrome (TS) is a genetic disorder occurring only in females where cardiovascular anomalies, particularly of the aorta, are frequently encountered. In this study, numerical simulations are applied to investigate the flow characteristics in four TS patient- related aortic arches (a normal geometry, dilatation, coarctation and elongation of the transverse aorta). The Quemada viscosity model was applied to account for the non-Newtonian behavior of blood. The blood is treated as a mixture consisting of water and red blood cells (RBC) where the RBCs are modeled as a convected scalar. The results show clear geometry effects where the flow structures and RBC distribution are significantly different between the aortas. Transitional flow is observed as a jet is formed due to a constriction in the descending aorta for the coarctation case. RBC dilution is found to vary between the ...
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A child with neurofibromatosis and hypertension also demonstrated renal artery stenosis, the most common cause of hypertension in children with neurofibromatosi
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Our site may use order forms to allow users to request information, products, and services.. Your Doctors Right to Privacy. We will respect your doctors right to privacy. A doctor typically does not give his/her e-mail address to the parents/guardians of patients. We will not provide the e-mail addresses of doctor(s) in the local practice to users of their site without the doctor(s) permission. Their site is restricted to use by whomever they wish, and they may deny access to their site to one or more prior users. In unusual cases, doctors may change their private sites access code and arrange for us to e-mail the new access code to approved users.. Cookies. We use cookies to deliver content specific to your interests and to save your doctors access code so you dont have to re-enter it each time you visit your doctors site on http://www.remedyconnect.com.. Links. This site contains links to other sites. RemedyConnect.com is not responsible for the privacy practices or the content of such ...
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On what basis do you make the claim that DNA has "mistakes galore, miscopies, additional sequences not found in the original, entire pieces cut out, crossovers, and yet, the organism still lives, still REPRODUCES AND HAS VIABLE OFFSPRING"? You obviously know nothing about benefits. My youngest daughter was born 2 years ago. We had no indication of any problems throughout the duration of the pregnancy. 30 minutes after she was delivered, she was taken to the nursury. My wife and I were notified minutes later that she was on an ambulance being rushed to a heart specialist. We soon found out she has Turner Syndrome; she is missing a chromosome. We spent 2 weeks in the NICU unit, sleeping in the waiting room after she underwent a balloon procedure to reduce the pressure gradient at her aortic valve. The valve is bicuspid, and a coarctation of her aorta was also compounding the problem. After letting her go home for a month, we then spent another month in ICU after she underwent open heart surgury. ...
The diagnostics of congenital heart disease, and especially the need for frequent lifelong postoperative follow-up examinations, require an imaging modality as gentle and reliable as possible. The method commonly used for this purpose ? echocardiography - is associated with some disadvantages, especially in older patients with an insufficient acoustic window. For these patients magnetic resonance imaging (MRI) is an alternative imaging modality. The aim of this study was to evaluate two functional MR methods, flow measurement with a flow phantom and ventricular function analysis in comparison to 3D echocardiography. These methods were performed in 6 different groups of patients with uncorrected or surgically corrected congenital heart diseases. 1. Beside a good correlation between the estimated pressure gradients in the area of stenoses and re-stenoses in patients with coarctation with the aid of MR flow measurements, three-dimensional reconstruction from MR angiography (MRA) data supplies ...
Our son, Tyson Hugh Hooper, was born with coarctation of the aorta, hypoplastic arch, and a transitional avsd. His first open heart surgery reconstructed his aorta and was on day 9 of life. His second open heart repair was not anticipated to be needed until two or three years of age. Ty had other plans. We spent the vast majority of his first 3 months of life at Vanderbilt as he went into heart failure and was diagnosed with pulmonary hypertension. As a result, the medical team concluded that he needed the repair much sooner than usually recommended, and at just shy of 3 months old Ty underwent his second life saving open heart surgery. God has already worked so many miracles in Tys life and the life of our family and we know he is using our story. Because of this, we are grateful for Tys special heart and feel beyond blessed that God chose us to travel this road. We ask for prayers as Ty continues to heal. We are praying for a full recovery and life without restrictions for Ty. We are praying ...
Our son, Tyson Hugh Hooper, was born with coarctation of the aorta, hypoplastic arch, and a transitional avsd. His first open heart surgery reconstructed his aorta and was on day 9 of life. His second open heart repair was not anticipated to be needed until two or three years of age. Ty had other plans. We spent the vast majority of his first 3 months of life at Vanderbilt as he went into heart failure and was diagnosed with pulmonary hypertension. As a result, the medical team concluded that he needed the repair much sooner than usually recommended, and at just shy of 3 months old Ty underwent his second life saving open heart surgery. God has already worked so many miracles in Tys life and the life of our family and we know he is using our story. Because of this, we are grateful for Tys special heart and feel beyond blessed that God chose us to travel this road. We ask for prayers as Ty continues to heal. We are praying for a full recovery and life without restrictions for Ty. We are praying ...
The aorta carries blood from the heart to the vessels that supply the body with blood. If part of the aorta is narrowed, it is hard for blood to pass through the artery. This is called coarctation of the
A 49-year-old female with past medical history of repaired aortic coarctation and alpha-gal allergy was diagnosed with severe aortic stenosis and a calcified bicuspid aortic valve was seen on TTE. Due to progression of her heart failure symptoms, aortic valve replacement was recommended. The patient was diagnosed with her alpha-gal allergy due to reaction consistent with anaphylaxis after eating pork or beef. She developed the allergy after an observed tick bite. The history of alpha-gal allergy raised concern for an anaphylactic response to administration of heparin intraoperatively. Concern for early calcification and dysfunction of a bioprosthetic valve due to her allergy led the patient to choose a mechanical aortic valve.. The patient was admitted preoperatively and was premedicated with 50 mg of prednisone every 8 h and 25 mg of diphenhydramine to decrease the risk of an adverse allergic reaction. After she was anesthetized, she received 125 mg methylprednisolone and 50 mg diphenhydramine ...
TY - JOUR. T1 - Linkage analysis of left ventricular outflow tract malformations (aortic valve stenosis, coarctation of the aorta, and hypoplastic left heart syndrome). AU - McBride, Kim L.. AU - Zender, Gloria A.. AU - Fitzgerald-Butt, Sara M.. AU - Koehler, Daniel. AU - Menesses-Diaz, Andres. AU - Fernbach, Susan. AU - Lee, Kwanghyuk. AU - Towbin, Jeffrey A.. AU - Leal, Suzanne. AU - Belmont, John W.. PY - 2009/1/15. Y1 - 2009/1/15. N2 - The left ventricular outflow tract (LVOT) malformations aortic valve stenosis (AVS), coarctation of the aorta (CoA), and hypoplastic left heart syndrome (HLHS) are significant causes of infant mortality. These three malformations are thought to share developmental pathogenetic mechanisms. A strong genetic component has been demonstrated earlier, but the underlying genetic etiologies are unknown. Our objective was to identify genetic susceptibility loci for the broad phenotype of LVOT malformations. We genotyped 411 microsatellites spaced at an average of 10 cM ...
Ventricular septal defect (VSD), Atrial septal defect (ASD), Patent ductus arteriosus (PDA), Mitral insufficiency (MI), Anterior mitral valve cleft (AMVC), Mitral valve cleft (MVC), Tricuspid insufficiency (TI), Aortic coarctation (AC), Bicuspid aortic valve (BAV), Mitral valve prolapsed (MVP), Cor triatriatum (CTA), Partial anomalous pulmonary venous connection (PAPVC), Total anomalous pulmonary venous connection (TAPVC) ...
Expertise, Disease and Conditions: Acute Myocardial Infarction (AMI), Adult Congenital Heart Disease, Angina, Angioplasty, Aortic Coarctation, Arrhythmia, Atrial Septal Defects (ASD), Balloon Valvuloplasty, Cardiac Catheterization, Cardiomyopathy, Cardiovascular Disease, Cardiovascular Diseases, Cardiovascular Interventions, Cardiovascular Medicine, Coronary Angiography, Coronary Artery Disease, Coronary Artery Stenting, Drug Eluting Stents, Extractional Atherectomy, Heart Attack, Heart Disease, Heart Failure, Interventional Cardiology, Interventional Radiology, Invasive Cardiology, Irregular Heartbeat, Ischemic Heart Disease, Laser Ablation, Mitral Stenosis, Myocardial Infarction, New Imaging Modalities, Patent Ductus Arteriosus (PDA), Patent Foramen Ovale, Percutaneous Coronary Intervention (PCI), Percutaneous Treatment of Valvular Stenosis, Pulmonary Stenosis, Rotational Atherectomy, Stenting, Treatment of Bypass Graft Disease with Distal Protection Devices, Valvular Heart Disease, ...
ABSTRACT- To clarify the relation of pericentral fibrosis to portal hypertension, measurements of portal vascular resistance in vitro and blood pressures of several key points in hepatic vascular pathways in vivo were undertaken in rats given dimethylnitrosamine. Administration of dimethylnitrosamine induced tortuosity and narrowing of the peripheral branches of the hepatic vein due to pericentral fibrosis. No significant change was produced in the sinusoids and the portal vein branches. The portal vascular resistance was increased and the portal vein pressure was elevated markedly. The blood pressure gradient was steep in the intrahepatic vein, but not in the intrahepatic portal vein or the sinusoids, as compared to control. These data suggest that deformation of the peripheral branches of the hepatic vein due to pericentral fibrosis causes a marked increase in vascular resistance in the intrahepatic hepatic vein, i.e. postsinusoidal portal hypertension. ...
aortic valve essay OBJECTIVE. Cardiac MDCT and cardiovascular MRI have become widely used for the evaluation of cardiovascular disease, including aortic valve disease. The purpose of this article is to present the cardiac MDCT and cardiovascular MRI findings of bicuspid aortic valve, its various complications, and other congenital cardiovascular malformations. Resume Writing Services Brisbane North! CONCLUSION. Radiologists should be aware of the clinical significance and the varied appearance of in research, bicuspid aortic valve at cardiac MDCT and cardiovascular MRI. Bicuspid aortic valve (BAV) is the most common congenital cardiovascular malformation, affecting approximately 0.5. Resume Writing Brisbane! 2% of the popu lation. BAV can coexist with other congenital cardiovascular malformations, particularly coarctation of the aorta (COA). New Cosmetologist Cover Letter! Patients with BAV are at increased risk of both valvular and vascular complications.. Serious valvular lesions include ...
Pregnant women with hypertension during labor and after one are specifically being monitored . Kidney Cyst: Symptoms Pain and Treatments.. We can feel lightheaded if our circulatory system isnt getting nough oxygen to our ain and this can happen to us following exercise due to Balance. Quitting smoking and limiting alcohol consumption help people Medical Marijuana Scientific Data. But even at the same blood alcohol level older adults may feel some of the effects of alcohol more strongly than younger people.. If you are taking spironolactone to lower blood pressure then 50 mg to 100 mg is given at first with dosages gradually increasing to 200 mg per day. A condition called coarctation of the aorta can cause blood pressure to be much higher in the right arm than in the left arm. Penna "Pressure pain threshold source in children with recurrent abdominal pain" Journal of Pediatric * Easy to handle manual inflation. Ask your health care provider if you should take any of your regular medicines on ...

Influence of Aortic Coarctation on Pulsatile Hemodynamics in the Proximal Aorta | CirculationInfluence of Aortic Coarctation on Pulsatile Hemodynamics in the Proximal Aorta | Circulation

Results were correlated with intraoperative measurements of aortic pressure in three young patients with aortic coarctation and ... Influence of Aortic Coarctation on Pulsatile Hemodynamics in the Proximal Aorta. MICHAEL F. OROURKE, TIMOTHY B. CARTMILL ... Distinctive changes in aortic impedance with coarctation were explained in terms of altered peripheral reflection. Such changes ... Pressure and flow were recorded in the ascending aorta of three dogs with aortic coarctation, induced surgically 3 months ...
more infohttp://circ.ahajournals.org/content/44/2/281

Number 10-18: Aortic Coarctation Repair with Associated Bicuspid Aortic Valve - Society for Cardiovascular Magnetic ResonanceNumber 10-18: Aortic Coarctation Repair with Associated Bicuspid Aortic Valve - Society for Cardiovascular Magnetic Resonance

Number 10-18: Aortic Coarctation Repair with Associated Bicuspid Aortic Valve. Case from: Camastra GS, Cacciotti L, Sbarbati S ... Echocardiography revealed a bicuspid aortic valve with dilated aortic root and a coarctation of the descending thoracic aorta ... Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar;31(3):711-8.. 4. Puranik R, ... 2. Lam YY, Kaya MG, Li W, Mahadevan VS, Khan AA, Henein MY, Mullen M. Effect of endovascular stenting of aortic coarctation on ...
more infohttp://scmr.org/page/COW1018/Number-10-18-Aortic-Coarctation-Repair-with-Associated-Bicuspid-Aortic.htm

Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload<...Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload<...

Yamashita, Y., Tatewaki, H., Matsumoto, T., & Shiose, A. (2018). Axillo-iliac artery bypass for recurrent aortic coarctation to ... Yamashita, Y, Tatewaki, H, Matsumoto, T & Shiose, A 2018, Axillo-iliac artery bypass for recurrent aortic coarctation to ... Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload. / Yamashita, Yoshiyuki; Tatewaki, ... Axillo-iliac artery bypass for recurrent aortic coarctation to reduce cardiac afterload. In: Interactive cardiovascular and ...
more infohttps://kyushu-u.pure.elsevier.com/en/publications/axillo-iliac-artery-bypass-for-recurrent-aortic-coarctation-to-re

Unusual findings in secondary hypertension: double orifice mitral associated to aortic coarctation, bicuspid aortic valve, and...Unusual findings in secondary hypertension: double orifice mitral associated to aortic coarctation, bicuspid aortic valve, and...

Owing to the suspicion of aortic coarctation, transthoracic echocardiography was performed, the aortic coarctation with ... Owing to the severity of the aortic coarctation and taking into account the anatomy and characteristics of the patient, he was ... ventricular septal defects or aortic coarctation. We report the case of a 15 years old boy, admitted for arterial hypertension ... No mitral or aortic regurgitation was documented by color Doppler flow imaging. The left ventricular ejection fraction was ...
more infohttps://intarchmed.biomedcentral.com/articles/10.1186/1755-7682-7-14

Echocardiographic Atlas of Adult Congenital Heart Disease | Hakimeh Sadeghian | SpringerEchocardiographic Atlas of Adult Congenital Heart Disease | Hakimeh Sadeghian | Springer

Coarctation of Aortic Valve, Bicuspid Aortic Valve, and Patent Foramen Ovale. Pages 495-497 ... Subvalvular Aortic Stenosis (Membranous Type with Circular Web) with Severe Left Ventricular Outflow Tract and Moderate Aortic ... Bicuspid Aortic Valve and Severe Aortic Regurgitation with Dilation of the Sinus of Valsalva ... Bicuspid Aortic Valve and Severe Aortic Regurgitation with Dilation of the Sinus of Valsalva ...
more infohttps://www.springer.com/gp/book/9783319129334

Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta: An observational study by...Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta: An observational study by...

keywords = "aortic coarctation, balloon angioplasty, stent, surgical treatment",. author = "Forbes, {Thomas J.} and Kim, { ... Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta: An observational study by ... Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta: An observational study by ... At short-term and intermediate follow-up, stent and surgical patients achieved superior hemodynamic and integrated aortic arch ...
more infohttps://augusta.pure.elsevier.com/en/publications/comparison-of-surgical-stent-and-balloon-angioplasty-treatment-of-2

Management of arch hypoplasia after successful coarctation repair<...Management of arch hypoplasia after successful coarctation repair<...

Unlike the use of extraanatomic bypass grafts, it allows complete relief of the obstruction, unhampered aortic growth, the ... Management of arch hypoplasia after successful coarctation repair. Maryann M. DeLeon, Serafin Y. DeLeon, Jose A. Quinones, ... Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a ... Management of arch hypoplasia after successful coarctation repair. / DeLeon, Maryann M.; DeLeon, Serafin Y.; Quinones, Jose A. ...
more infohttps://researchexperts.utmb.edu/en/publications/management-of-arch-hypoplasia-after-successful-coarctation-repair

Congenital Heart Defects - UTMCCongenital Heart Defects - UTMC

A narrowing (stenosis) just below the aortic valve also known as aortic stenosis (OS). ... Coarctation of the Aorta (CoA) *A narrowing of the major artery (the aorta) that carries blood to the body. ...
more infohttps://www.utmedicalcenter.org/es/medical-care/medical-services/procedures-treatments/congenital-heart-defects/

Aortic Coarctation: Practice Essentials, Background, PathophysiologyAortic Coarctation: Practice Essentials, Background, Pathophysiology

Coarctation of the aorta is a narrowing of the aorta most commonly found just distal to the origin of the left subclavian ... encoded search term (Aortic Coarctation) and Aortic Coarctation What to Read Next on Medscape. Related Conditions and Diseases ... The following surgical procedures have been performed to treat aortic coarctation:. * Resection of the coarctation site and end ... The prognosis for untreated aortic coarctation is poor. About 80% of untreated patients die of aortic dissection or rupture, ...
more infohttps://emedicine.medscape.com/article/150369-overview

Infrarenal aortic coarctation.Infrarenal aortic coarctation.

Hypoplastic infrarenal aorta or infrarenal aortic coarctation is an uncommon vascular pathology characterized with diffuse ... Aortic Coarctation / diagnosis*, surgery. Aortography. Blood Vessel Prosthesis Implantation. Diagnosis, Differential. ... Here, we report a 49-year-old male patient diagnosed with abdominal aortic coarctation together with the review of the ... 20223618 - Technique of interventional repair in adult aortic coarctation.. 20347698 - Treatment of a pelvic arteriovenous ...
more infohttp://www.biomedsearch.com/nih/Infrarenal-aortic-coarctation/20694768.html

Aortic coarctation | HeartAortic coarctation | Heart

Diagnosis, imaging and clinical management of aortic coarctation Elles J Dijkema, Tim Leiner, Heynric B Grotenhuis ...
more infohttps://heart.bmj.com/keyword/aortic-coarctation

Aortic Coarctation Imaging: Overview, Radiography, Magnetic Resonance ImagingAortic Coarctation Imaging: Overview, Radiography, Magnetic Resonance Imaging

Coarctation of the aorta is a common congenital cardiovascular defect characterized by upper-body hypertension resulting from ... encoded search term (Aortic%20Coarctation%20Imaging) and Aortic Coarctation Imaging What to Read Next on Medscape. Related ... is diagnostic of aortic coarctation. It is the result of obstruction of blood flow at the narrowed aortic segment, in ... Aortic Coarctation Imaging. Updated: Nov 24, 2015 * Author: Vibhuti N Singh, MD, MPH, FACC, FSCAI; Chief Editor: Eugene C Lin, ...
more infohttps://emedicine.medscape.com/article/416623-overview

Aortic Coarctation-Adult - HealthLibraryAortic Coarctation-Adult - HealthLibrary

Aortic Coarctation-Adult. (Coarctation of the Aorta-Adult). by Krisha McCoy, MS ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... There are no current guidelines to prevent aortic coarctation because it is a congenital defect. ...
more infohttp://healthlibrary.epnet.com/GetContent.aspx?token=d168334d-e19b-432f-a759-e5d7d5fc1440&chunkiid=191795

Pregnancy Complicated with Severe Recurrent Aortic Coarctation: A Case ReportPregnancy Complicated with Severe Recurrent Aortic Coarctation: A Case Report

... Celal Yavuz,1 Hatice Ender Soydinc,2 Güven ... "Pregnancy Complicated with Severe Recurrent Aortic Coarctation: A Case Report," Case Reports in Vascular Medicine, vol. 2012, ...
more infohttps://www.hindawi.com/journals/crivam/2012/865035/cta/

Aortic Coarctation -- Adult | St. Davids HealthCareAortic Coarctation -- Adult | St. David's HealthCare

Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
more infohttps://stdavids.com/hl/?/191795/Aortic-coarctation

Aortic Coarctation -- Child | St. Davids HealthCareAortic Coarctation -- Child | St. David's HealthCare

Learn more about Aortic Coarctation -- Child at St. Davids HealthCare DefinitionCausesRisk ... Aortic coarctation (AC) is the narrowing of this artery. This slows or blocks blood flow. ... Effectiveness and safety of balloon dilation of native aortic coarctation in premature and neonates weighing , or = 2,500 grams ... Vijayalakshmi K, Griffiths A, Hasan A, OSullivan J. Late hazards after repair of coarctation of the aorta. BMJ. 2008;336(7647 ...
more infohttps://stdavids.com/hl/?/615135/Coarctation-of-the-aorta

The Challenges of Redo Aortic Coarctation Repair in Adults | SpringerLinkThe Challenges of Redo Aortic Coarctation Repair in Adults | SpringerLink

Re-coarctation or restenosis of the aorta following treatment is a... ... Purpose of Review Aortic coarctation is a common congenital abnormality causing significant morbidity and mortality if not ... Extraanatomic aortic bypass for repair of aortic arch coarctation via sternotomy: midterm clinical and magnetic resonance ... Risk factors for aortic complications in adults with coarctation of the aorta. J Am Coll Cardiol. 2004;44(8):1641-7.CrossRef ...
more infohttps://link.springer.com/article/10.1007%2Fs11886-019-1195-8

Aortic coarctation diagnosed by magnetic resonance angiography | HeartAortic coarctation diagnosed by magnetic resonance angiography | Heart

A 20 year old man was found to be hypertensive on routine screening. Examination revealed an absent right and barely palpable left femoral arterial pulse. Radiofemoral delay was present and pulsations were palpable over both scapulae. Parasaggital gadolinium enhanced magnetic resonance angiography (left) demonstrates a uniform 3 cm narrowing in the proximal descending aorta (d), which terminates in a discrete stricture before returning to a normal calibre (a, ascending aorta). Internal mammary artery hypertrophy is noted in the retrosternal. ...
more infohttp://heart.bmj.com/content/81/6/671

Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.  - PubMed - NCBIChemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. - PubMed - NCBI

... disrupts aortic blood flow in a region and physiological manner akin to aortic coarctation in humans. Here we use a whole- ... Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.. Peterson RT, Shaw SY, Peterson TA, ... organism, phenotype-based, small-molecule screen to discover a class of compounds that suppress the coarctation phenotype and ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/15097998?dopt=Abstract

A fatal case of undiagnosed aortic coarctationA fatal case of undiagnosed aortic coarctation

Aortic coarctation with secondary ruptured thoracic aortic aneurysm, active extravasation, hemothorax, and hemomediastinum. ... stroke and aortic dissection can also develop.2 This case seems unusual since today most people with aortic coarctation are ... Repair of coarctation-related aortic arch aneurysm and ventricular septal defect in an adolescent. Tex Heart Inst J. 2008;35(4 ... Historically, when aortic coarctation is untreated, the median age of death was 30 years. The leading causes of death included ...
more infohttps://appliedradiology.com/articles/a-fatal-case-of-undiagnosed-aortic-coarctation

Aortic CoarctationAortic Coarctation

What Is Aortic Coarctation?. Coarctation of the aorta (CoA) is a congenital malformation of the aorta. The condition is also ... Aortic Coarctation. Coarctation of the aorta is a congenital malformation of the aorta in which part of the aorta is ... What Causes Aortic Coarctation?. CoA is one of several common types of congenital heart malformations. CoA may occur alone. It ... How Is Aortic Coarctation Diagnosed?. A newborns first examination will usually reveal CoA. Your babys doctor may detect ...
more infohttps://www.aarpmedicareplans.com/health/coarctation-of-the-aorta?hlpage=health_center&loc=basic_info_tab

Aortic Coarctation -- Adult | West Florida HospitalAortic Coarctation -- Adult | West Florida Hospital

Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
more infohttps://westfloridahospital.com/hl/?/2010817074/Aortic-Coarctation----Adult&com.dotmarketing.htmlpage.language=1

Aortic Coarctation -- Adult | Grand Strand HealthAortic Coarctation -- Adult | Grand Strand Health

Learn more about Aortic Coarctation -- Adult at Grand Strand Medical Center DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
more infohttps://grandstrandmed.com/hl/?/191795/sp&com.dotmarketing.htmlpage.language=1

Aortic Coarctation -- Adult | West Florida HospitalAortic Coarctation -- Adult | West Florida Hospital

Learn more about Aortic Coarctation -- Adult at West Florida Hospital DefinitionCausesRisk ... Aortic coarctation is the narrowing of the aorta which slows or blocks the blood flow. It is often associated with other heart ... Aortic coarctation is a congenital heart defect, which means it is present at birth. It occurs because of a problem with the ... Coarctation of aorta. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116066/Coarctation-of- ...
more infohttps://westfloridahospital.com/hl/?/191795/Aortic-coarctation---adult&com.dotmarketing.htmlpage.language=1
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