Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.Aneurysm: Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)Aortic Aneurysm, Thoracic: An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.Aortic Rupture: The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.Aneurysm, Infected: Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.Blood Vessel Prosthesis Implantation: Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.Aorta, Abdominal: The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.Aortography: Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.Aneurysm, Dissecting: Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.Vascular Surgical Procedures: Operative procedures for the treatment of vascular disorders.Iliac Aneurysm: Abnormal balloon- or sac-like dilatation in the wall of any one of the iliac arteries including the common, the internal, or the external ILIAC ARTERY.Heart Aneurysm: A localized bulging or dilatation in the muscle wall of a heart (MYOCARDIUM), usually in the LEFT VENTRICLE. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are HEMATOMA caused by myocardial rupture.Endovascular Procedures: Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Embolization, Therapeutic: A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Coronary Aneurysm: Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.Aortitis: Inflammation of the wall of the AORTA.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Aneurysm, False: Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Endoleak: Postoperative hemorrhage from an endovascular AORTIC ANEURYSM repaired with endoluminal placement of stent grafts (BLOOD VESSEL PROSTHESIS IMPLANTATION). It is associated with pressurization, expansion, and eventual rupture of the aneurysm.Cerebral Angiography: Radiography of the vascular system of the brain after injection of a contrast medium.Surgical Procedures, Elective: Surgery which could be postponed or not done at all without danger to the patient. Elective surgery includes procedures to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risk to patients, e.g., cosmetic or contraceptive surgery.Iliac Artery: Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.Angiography, Digital Subtraction: A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.Polyethylene Terephthalates: Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.Angioplasty: Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.Angiography: Radiography of blood vessels after injection of a contrast medium.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.Renal Artery: A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.Dilatation, Pathologic: The condition of an anatomical structure's being dilated beyond normal dimensions.Pancreatic Elastase: A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Surgical Instruments: Hand-held tools or implements used by health professionals for the performance of surgical tasks.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.Aorta, Thoracic: The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.Vascular Fistula: An abnormal passage between two or more BLOOD VESSELS, between ARTERIES; VEINS; or between an artery and a vein.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Aortic Diseases: Pathological processes involving any part of the AORTA.ElastinForeign-Body Migration: Migration of a foreign body from its original location to some other location in the body.Mesenteric Artery, Inferior: The artery supplying nearly all the left half of the transverse colon, the whole of the descending colon, the sigmoid colon, and the greater part of the rectum. It is smaller than the superior mesenteric artery (MESENTERIC ARTERY, SUPERIOR) and arises from the aorta above its bifurcation into the common iliac arteries.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Paraplegia: Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.Spinal Cord Ischemia: Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.Esophageal Fistula: Abnormal passage communicating with the ESOPHAGUS. The most common type is TRACHEOESOPHAGEAL FISTULA between the esophagus and the TRACHEA.Celiac Artery: The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.Aorta: The main trunk of the systemic arteries.Patient Selection: Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.Mesenteric Artery, Superior: A large vessel supplying the whole length of the small intestine except the superior part of the duodenum. It also supplies the cecum and the ascending part of the colon and about half the transverse part of the colon. It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Imaging, Three-Dimensional: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.Radiography, Interventional: Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.Matrix Metalloproteinase 9: An endopeptidase that is structurally similar to MATRIX METALLOPROTEINASE 2. It degrades GELATIN types I and V; COLLAGEN TYPE IV; and COLLAGEN TYPE V.Hospital Mortality: A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.Balloon Occlusion: Use of a balloon CATHETER to block the flow of blood through an artery or vein.Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.Femoral Artery: The main artery of the thigh, a continuation of the external iliac artery.Paraparesis: Mild to moderate loss of bilateral lower extremity motor function, which may be a manifestation of SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; MUSCULAR DISEASES; INTRACRANIAL HYPERTENSION; parasagittal brain lesions; and other conditions.Polytetrafluoroethylene: Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Length of Stay: The period of confinement of a patient to a hospital or other health facility.Buttocks: Either of two fleshy protuberances at the lower posterior section of the trunk or HIP in humans and primate on which a person or animal sits, consisting of gluteal MUSCLES and fat.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Tomography, Spiral Computed: Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.Intestinal Fistula: An abnormal anatomical passage between the INTESTINE, and another segment of the intestine or other organs. External intestinal fistula is connected to the SKIN (enterocutaneous fistula). Internal intestinal fistula can be connected to a number of organs, such as STOMACH (gastrocolic fistula), the BILIARY TRACT (cholecystoduodenal fistula), or the URINARY BLADDER of the URINARY TRACT (colovesical fistula). Risk factors include inflammatory processes, cancer, radiation treatment, and surgical misadventures (MEDICAL ERRORS).Elastic Tissue: Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.Constriction: The act of constricting.Anterior Cerebral Artery: Artery formed by the bifurcation of the internal carotid artery (CAROTID ARTERY, INTERNAL). Branches of the anterior cerebral artery supply the CAUDATE NUCLEUS; INTERNAL CAPSULE; PUTAMEN; SEPTAL NUCLEI; GYRUS CINGULI; and surfaces of the FRONTAL LOBE and PARIETAL LOBE.Carotid Artery, Internal: Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.Matrix Metalloproteinase 2: A secreted endopeptidase homologous with INTERSTITIAL COLLAGENASE, but which possesses an additional fibronectin-like domain.Databases as Topic: Organized collections of computer records, standardized in format and content, that are stored in any of a variety of computer-readable modes. They are the basic sets of data from which computer-readable files are created. (from ALA Glossary of Library and Information Science, 1983)Arteriovenous Fistula: An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Surgical Procedures, Minimally Invasive: Procedures that avoid use of open, invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device.Suture Techniques: Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).Neurosurgical Procedures: Surgery performed on the nervous system or its parts.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Laparotomy: Incision into the side of the abdomen between the ribs and pelvis.Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.Equipment Design: Methods of creating machines and devices.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Vascular Patency: The degree to which BLOOD VESSELS are not blocked or obstructed.Calcium Chloride: A salt used to replenish calcium levels, as an acid-producing diuretic, and as an antidote for magnesium poisoning.Platinum: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Loeys-Dietz Syndrome: An autosomal dominant aneurysm with multisystem abnormalities caused by increased TGF-BETA signaling due to mutations in type I or II of TGF-BETA RECEPTOR. Additional craniofacial features include CLEFT PALATE; CRANIOSYNOSTOSIS; HYPERTELORISM; or bifid uvula. Phenotypes closely resemble MARFAN SYNDROME; Marfanoid craniosynostosis syndrome (Shprintzen-Goldberg syndrome); and EHLERS-DANLOS SYNDROME.Replantation: Restoration of an organ or other structure to its original site.Retroperitoneal Fibrosis: A slowly progressive condition of unknown etiology, characterized by deposition of fibrous tissue in the retroperitoneal space compressing the ureters, great vessels, bile duct, and other structures. When associated with abdominal aortic aneurysm, it may be called chronic periaortitis or inflammatory perianeurysmal fibrosis.Retreatment: The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Emergency Treatment: First aid or other immediate intervention for accidents or medical conditions requiring immediate care and treatment before definitive medical and surgical management can be procured.Subclavian Artery: Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.Splenic Artery: The largest branch of the celiac trunk with distribution to the spleen, pancreas, stomach and greater omentum.Transducers, Pressure: Transducers that are activated by pressure changes, e.g., blood pressure.Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).Emergencies: Situations or conditions requiring immediate intervention to avoid serious adverse results.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Axillary Artery: The continuation of the subclavian artery; it distributes over the upper limb, axilla, chest and shoulder.Sinus of Valsalva: The dilatation of the aortic wall behind each of the cusps of the aortic valve.Doxycycline: A synthetic tetracycline derivative with similar antimicrobial activity.Vascular Grafting: Surgical insertion of BLOOD VESSEL PROSTHESES, or transplanted BLOOD VESSELS, or other biological material to repair injured or diseased blood vessels.Blood Loss, Surgical: Loss of blood during a surgical procedure.Viscera: Any of the large interior organs in any one of the three great cavities of the body, especially in the abdomen.Vertebral Artery: The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Radiographic Image Interpretation, Computer-Assisted: Computer systems or networks designed to provide radiographic interpretive information.Finite Element Analysis: A computer based method of simulating or analyzing the behavior of structures or components.Cerebral Arteries: The arterial blood vessels supplying the CEREBRUM.Retroperitoneal Space: An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.Ligation: Application of a ligature to tie a vessel or strangulate a part.Matrix Metalloproteinases: A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components.Cardiovascular Surgical Procedures: Surgery performed on the heart or blood vessels.Fistula: Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body.Mass Screening: Organized periodic procedures performed on large groups of people for the purpose of detecting disease.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Device Removal: Removal of an implanted therapeutic or prosthetic device.Specialties, Surgical: Various branches of surgical practice limited to specialized areas.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Angiotensin II: An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.Stress, Mechanical: A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.Recurrence: The return of a sign, symptom, or disease after a remission.Posterior Cerebral Artery: Artery formed by the bifurcation of the BASILAR ARTERY. Branches of the posterior cerebral artery supply portions of the OCCIPITAL LOBE; PARIETAL LOBE; inferior temporal gyrus, brainstem, and CHOROID PLEXUS.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.Popliteal Artery: The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.Ultrasonography, Doppler, Duplex: Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.Catheterization, Peripheral: Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.Syphilis, Cardiovascular: Cardiovascular manifestations of SYPHILIS, an infection of TREPONEMA PALLIDUM. In the late stage of syphilis, sometimes 20-30 years after the initial infection, damages are often seen in the blood vessels including the AORTA and the AORTIC VALVE. Clinical signs include syphilitic aortitis, aortic insufficiency, or aortic ANEURYSM.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.Basilar Artery: The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.Behcet Syndrome: Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.Angioscopy: Endoscopic examination, therapy or surgery performed on the interior of blood vessels.Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Apolipoproteins E: A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.Circle of Willis: A polygonal anastomosis at the base of the brain formed by the internal carotid (CAROTID ARTERY, INTERNAL), proximal parts of the anterior, middle, and posterior cerebral arteries (ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; POSTERIOR CEREBRAL ARTERY), the anterior communicating artery and the posterior communicating arteries.Craniotomy: Any operation on the cranium or incision into the cranium. (Dorland, 28th ed)Microsurgery: The performance of surgical procedures with the aid of a microscope.Coated Materials, Biocompatible: Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.Heart Bypass, Left: Diversion of the flow of blood from the pulmonary veins directly to the aorta, avoiding the left atrium and the left ventricle (Dorland, 27th ed). This is a temporary procedure usually performed to assist other surgical procedures.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Equipment Safety: Freedom of equipment from actual or potential hazards.Tuberculosis, Cardiovascular: Pathological conditions of the CARDIOVASCULAR SYSTEM caused by infection of MYCOBACTERIUM TUBERCULOSIS. Tuberculosis involvement may include the HEART; the BLOOD VESSELS; or the PERICARDIUM.Alloys: A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Hospital Costs: The expenses incurred by a hospital in providing care. The hospital costs attributed to a particular patient care episode include the direct costs plus an appropriate proportion of the overhead for administration, personnel, building maintenance, equipment, etc. Hospital costs are one of the factors which determine HOSPITAL CHARGES (the price the hospital sets for its services).Statistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)Brachiocephalic Trunk: The first and largest artery branching from the aortic arch. It distributes blood to the right side of the head and neck and to the right arm.Cerebral Revascularization: Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Matrix Metalloproteinase 12: A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.Mucocutaneous Lymph Node Syndrome: An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.Aortic Valve: The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.Thoracotomy: Surgical incision into the chest wall.Prosthesis-Related Infections: Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).Colitis, Ischemic: Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.Models, Anatomic: Three-dimensional representation to show anatomic structures. Models may be used in place of intact animals or organisms for teaching, practice, and study.Endoscopy: Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.Systemic Inflammatory Response Syndrome: A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA 90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.Vertebral Artery Dissection: Splitting of the vessel wall in the VERTEBRAL ARTERY. Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the vertebral artery, aneurysm formation, or THROMBOEMBOLISM. Vertebral artery dissection is often associated with TRAUMA and injuries to the head-neck region but can occur spontaneously.Postoperative Period: The period following a surgical operation.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Carotid Artery, Internal, Dissection: The splitting of the vessel wall in one or both (left and right) internal carotid arteries (CAROTID ARTERY, INTERNAL). Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the internal carotid artery and aneurysm formation.Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Carotid Artery, Common: The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.Postoperative Hemorrhage: Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Mechanical Thrombolysis: Procedures to cause the disintegration of THROMBI by physical interventions.Peripheral Vascular Diseases: Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Equipment Failure Analysis: The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.Psoas Abscess: Abscess of the PSOAS MUSCLES resulting usually from disease of the lumbar vertebrae, with the pus descending into the muscle sheath. The infection is most commonly tuberculous or staphylococcal.Myocytes, Smooth Muscle: Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).Hematoma: A collection of blood outside the BLOOD VESSELS. Hematoma can be localized in an organ, space, or tissue.

Repair of ruptured thoracoabdominal aortic aneurysm is worthwhile in selected cases. (1/1156)

INTRODUCTION: The risks and benefits of operating on patients with ruptured thoracoabdominal aortic aneurysm (TAAA) have not been defined. The aim of the present study is to report this unit's experience with operations performed for ruptured TAAA over a 10-year period. METHODS: Interrogation of a prospectively gathered computerised database. PATIENTS: Between 1 January 1983 and 30 June 1996, 188 consecutive patients with TAAA were operated on, of whom 23 (12%) were operated for rupture. RESULTS: There were nine survivors (40%). Patients whose preoperative systolic blood pressure remained above 100 mmHg were significantly more likely to survive (4/8 vs. 13/15, p = 0.03 by Fisher's exact test). Survival was also related to Crawford type: type I (two of three survived); II (none of six); III (two of six); and IV (five of eight). All non-type II, non-shocked patients survived operation. Survivors spent a median of 28 (range 10-66) postoperative days in hospital, of which a median of 6 (range 2-24) days were spent in the intensive care unit. Survivor morbidity comprised prolonged ventilation (> 5 days) (n = 3); tracheostomy (n = 1); and temporary haemofiltration (n = 2). No survivor developed paraplegia or required permanent dialysis. CONCLUSIONS: Patients in shock with a Crawford type II aneurysm have such a poor prognosis that intervention has to be questioned except in the most favourable of circumstances. However, patients with types I, III and IV who are not shocked on presentation can be salvaged and, where possible, should be transferred to a unit where appropriate expertise and facilities are available.  (+info)

Rupture of aortic aneurysm with right-sided haemothorax. (2/1156)

A 62-yr-old male with a history of high blood pressure was admitted for persistent dyspnoea and a right-sided pleural effusion, complicated by a recent episode of shock. There was no history of trauma and the patient denied any thoracic pain. A chest tube was inserted which released nonclotting bloody fluid. A thoracic computed tomographic scan of the chest revealed an aneurysm of the inferior third of the descending thoracic aorta. The patient underwent a successful prosthetic graft replacement. We emphasize that rupture of aortic aneurysms should be considered in the evaluation of spontaneous haemothorax even if it is right-sided and not associated with pain.  (+info)

The value of late computed tomographic scanning in identification of vascular abnormalities after abdominal aortic aneurysm repair. (3/1156)

PURPOSE: The purpose of this study was to determine the prevalence of late arterial abnormalities after aortic aneurysm repair and thus to suggest a routine for postoperative radiologic follow-up examination and to establish reference criteria for endovascular repair. METHODS: Computed tomographic (CT) scan follow-up examination was obtained at 8 to 9 years after abdominal aortic aneurysm (AAA) repair on a cohort of patients enrolled in the Canadian Aneurysm Study. The original registry consisted of 680 patients who underwent repair of nonruptured AAA. When the request for CT scan follow-up examination was sent in 1994, 251 patients were alive and potentially available for CT scan follow-up examination and 94 patients agreed to undergo abdominal and thoracic CT scanning procedures. Each scan was interpreted independently by two vascular radiologists. RESULTS: For analysis, the aorta was divided into five defined segments and an aneurysm was defined as a more than 50% enlargement from the expected normal value as defined in the reporting standards for aneurysms. With this strict definition, 64.9% of patients had aneurysmal dilatation and the abnormality was considered as a possible indication for surgical repair in 13.8%. Of the 39 patients who underwent initial repair with a tube graft, 12 (30.8%) were found to have an iliac aneurysm and six of these aneurysms (15.4%) were of possible surgical significance. Graft dilatation was observed from the time of operation (median graft size of 18 mm) to a median size of 22 mm as measured by means of CT scanning at follow-up examination. Fluid or thrombus was seen around the graft in 28% of the cases, and bowel was believed to be intimately associated with the graft in 7%. CONCLUSION: Late follow-up CT scans after AAA repair often show vascular abnormalities. Most of these abnormalities are not clinically significant, but, in 13.8% of patients, the thoracic or abdominal aortic segment was aneurysmal and, in 15.4% of patients who underwent tube graft placement, one of the iliac arteries was significantly abnormal to warrant consideration for surgical repair. On the basis of these findings, a routine CT follow-up examination after 5 years is recommended. This study provides a population-based study for comparison with the results of endovascular repair.  (+info)

Endovascular repair of a descending thoracic aortic aneurysm: a tip for systemic pressure reduction. (4/1156)

A proposed technique for systemic pressure reduction during deployment of a stent graft was studied. A 67-year-old man, who had a descending thoracic aneurysm, was successfully treated with an endovascular procedure. An occluding balloon was introduced into the inferior vena cava (IVC) through the femoral vein. The balloon volume was manipulated with carbon dioxide gas to reduce the venous return, resulting in a transient and well-controlled hypotension. This IVC-occluding technique for systemic pressure reduction may be safe and convenient to minimize distal migration of stent grafts.  (+info)

Endovascular stent graft repair of aortopulmonary fistula. (5/1156)

Two patients who had aortopulmonary fistula of postoperative origin with hemoptysis underwent successful repair by means of an endovascular stent graft procedure. One patient had undergone repeated thoracotomies two times, and the other one time to repair anastomotic aneurysms of the descending aorta after surgery for Takayasu's arteritis. A self-expanding stainless steel stent covered with a Dacron graft was inserted into the lesion through the external iliac or femoral artery. The patients recovered well, with no signs of infection or recurrent hemoptysis 8 months after the procedure. Endovascular stent grafting may be a therapeutic option for treating patients with aortopulmonary fistula.  (+info)

Intraoperative transoesophageal echocardiography as an adjuvant to fluoroscopy during endovascular thoracic aortic repair. (6/1156)

OBJECTIVES: To define the utility of intraoperative transeophageal echocardiography (TEE) during endovascular thoracic aortic repair. DESIGN: Retrospective study. MATERIALS: Five patients underwent six transluminal endovascular stent-graft procedures for repair of thoracic aortic disease. METHODS: After induction of anaesthesia, a multiplane or biplane TEE probe was placed to obtain views of the diseased aorta. Both transverse and longitudinal planes of the aortic arch and descending thoracic aortic segments were imaged. The aortic pathology was confirmed by TEE and the proximal and distal extents of the intrathoracic lesion were defined. Doppler and colour-flow imaging was used to identify flow patterns through the aorta before and after stent-graft deployment. RESULTS: Visualisation and confirmation of the aortic pathology by ultrasonography was accomplished in all patients. TEE was able to confirm proper placement of the endograft relative to the aortic lesion after deployment and was able to confirm exclusion of blood flow into the aneurysm sacs. CONCLUSIONS: TEE may facilitate repair by confirming aortic pathology, identifying endograft placement, assessment of the adequacy of aneurysm sack isolation, as well as dynamic intraoperative cardiac assessment.  (+info)

The role of radial elastic properties in the development of aortic dissections. (7/1156)

PURPOSE: The response of the upper and lower thoracic aorta to radial tensile stresses was compared with the response to circumferential and longitudinal stresses to understand the role of tensile stress in the tearing phase of an aortic dissection. METHODS: Square tissue samples (1.6 by 1.6 cm) were cut from the upper and lower segments of six porcine thoracic aortas and were elongated in the radial direction with a tensile testing machine. The radial extensibility of the thoracic aorta was compared with adjacent tissue samples that were tested in tension in the circumferential and longitudinal directions based on Young's modulus (ie, the ratio of tensile stress to strain). RESULTS: The elastic properties of the thoracic aorta in the radial direction were markedly different from both the circumferential and longitudinal properties. The average Young's modulus (calculated immediately before failing) was significantly lower in the radial direction for both the upper and lower thoracic segments (61.4 +/- 4.3 kPa, SEM) than the Young's modulus of corresponding segments in the circumferential and longitudinal directions that were not tested to failure (151.1 +/- 8.6 kPa and 112.7 +/- 9.2 kPa, respectively; P <. 05). Sections 7 micrometer thick were collected from four samples obtained from one upper thoracic aorta that were strained at 0, 1.0, 2.5, and 4.0 and then stained either with Movat's pentachrome or with hematoxylin and eosin. Histological analysis of the samples stressed in the radial direction revealed that smooth muscle cells were torn loose from their attachments to each other and to adjacent elastin. CONCLUSION: Although the aorta normally functions under radial compressive stresses associated with lumen blood pressure, these results show that the aorta tears radially at a much lower value of stress than would have been predicted from previous studies that have reported longitudinal and circumferential Young's modulus. This could explain why dissections propagate readily once the initial tear occurs.  (+info)

Chronic aneurysm of the descending thoracic aorta presenting with right pleural effusion and left phrenic paralysis. (8/1156)

A 62-year-old man was admitted to the emergency department with chronic dysphagia and lower back pain. Chest radiography revealed a wide mediastinal shadow and an elevated left diaphragm, which proved to be secondary to left phrenic paralysis. The patient was diagnosed with an aneurysm of the descending thoracic aorta and was admitted to the hospital. After the patient was admitted, the aneurysm ruptured into the right chest. The patient underwent an emergency operation to replace the ruptured segment with a synthetic graft. Postoperative recovery and follow-up were uneventful. This report describes an unusual presentation of a thoracic aortic aneurysm. Hemidiaphragmatic paralysis caused by compression of the phrenic nerve is an unusual complication that, to our knowledge, has not been previously reported.  (+info)

TY - JOUR. T1 - Transient paraplegia after stent grafting of a descending thoracic aortic aneurysm treated with cerebrospinal fluid drainage. AU - Fuchs, Ralph J.. AU - Lee, W. Anthony. AU - Seubert, Christoph N.. AU - Gelman, Simon. AU - Yeager, Anita. PY - 2003/2. Y1 - 2003/2. N2 - We present a case of descending thoracic aortic aneurysm repair using an endovascular stent graft, complicated by postoperative paraplegia, which was successfully treated by placing a spinal drain. The case highlights the importance of the concept of collateral flow to the spinal cord and of choosing an anesthetic technique that allows immediate postoperative evaluation of lower extremity neurologic function.. AB - We present a case of descending thoracic aortic aneurysm repair using an endovascular stent graft, complicated by postoperative paraplegia, which was successfully treated by placing a spinal drain. The case highlights the importance of the concept of collateral flow to the spinal cord and of choosing an ...
Thoracic aortic aneurysms occur in 3 to 4% of persons older than 65 years. The incidence of thoracic aneurysm is approximately 6 to 10 cases per 100,000 person years with the incidence of thoracic aneurysm rupture occurring in 3.5 per 100,000 persons. The average age of diagnosis is 69 years. The prevalence of thoracic aortic aneurysm is up to 4.2% of the general population without hypertension. Most thoracic aortic aneurysms occur in the ascending aorta or the aortic arch. Aneurysm rupture accounts for 60% of deaths. Degenerative aneurysm associated with advanced age most commonly seen. There is no difference between the incidence in males versus females. Arteriosclerosis is the most common cause of thoracic aneurysm involving the descending aorta and aortic arch. It is most common in older individuals with males affected more than females. The etiology of thoracic aortic aneurysm is dependent on the location of the aneurysm. Ascending thoracic aorta aneurysm can be caused by cystic medial ...
Thoracic endovascular aneurysm repair (TEVAR) is a safe and effective procedure for the treatment of thoracic aortic aneurysms (TAAs).
PURPOSE: To present a technique for renal and visceral revascularization allowing complete endovascular treatment of a ruptured type IV thoracoabdominal aneurysm using devices already stocked in most centers performing endovascular aneurysm repair. TECHNIQUE: Open arterial access is obtained to both common femoral arteries and the left subclavian artery (LSA). Access to the visceral and renal arteries is obtained through separate 8-F sheaths for each visceral and renal branch. Both visceral arteries (celiac trunk and superior mesenteric artery) are accessed through 2 separate sheaths placed into the LSA, and both renal arteries are accessed through 2 separate sheaths placed into the left common femoral artery. Corresponding covered stents are introduced and positioned in the celiac trunk, superior mesenteric artery, and both renal arteries but not deployed. The aortic stent-graft is then introduced and deployed through the right common femoral artery. Once the aneurysm exclusion is completed, ...
The data presented here support the conclusion that heterozygous loss-of-function mutations in LOX, specifically variants that disrupt the catalytic activity or lead to haploinsufficiency, predispose to thoracic aortic aneurysms and acute aortic dissections. Overlapping syndromic features of Marfan syndrome, such as pectus deformities and striae, were reported in family members with LOX variants, but these features were not sufficient to meet diagnostic criteria for Marfan syndrome.13 Thoracic aortic aneurysms in these individuals are either aortic root aneurysms or fusiform aneurysms, involving both the aortic root and ascending aorta. Although mutation carriers died of ascending aortic dissections, there were no reports of aortic dissections with minimal enlargement of the ascending aorta. None of the affected individuals presented with descending thoracic aortic aneurysms or dissections. Interestingly, a bicuspid aortic valve was identified in 3 of 18 individuals with LOX mutations. It is ...
SCVS 2020 Abstracts: Single-stage Hybrid Repair Of A Thoracoabdominal Aortic Aneurysm Complicated By Chronic Type B Aortic Dissection And Kommerells Diverticulum Via Simultaneous Median Sternotomy And Laparotomy
The aorta is the artery that carries oxygen-rich blood away from the heart and on to other arteries that distribute it throughout the body. A thoracic aortic aneurysm occurs when a "balloon" forms in a weakened area of the aorta wall within the chest cavity. The weakened vessel wall is often caused by atherosclerosis. Thoracic aneurysm may occur in three parts of the thoracic aorta: the ascending aorta, the descending aorta or the aortic arch. A minor thoracic aortic aneurysm may have little effect on an individual, but can also be life-threatening and fatal if it bursts and causes severe internal bleeding. Symptoms of thoracic aortic aneurysm may include:. ...
Ascending thoracic aortic aneurysm (ATAA) is defined as a dilatation of the ascending aorta producing a cross sectional diameter more than 1.5 times its normal value; values between 1.1 and 1.5 are considered dilated or ectatic ascending aorta. Normal values have been established by different imaging techniques: echocardiography, computed tomography (CT) and magnetic resonance imaging (MRI)1-3 (table 1). Aneurysmal disease of the aorta is clinically important since, as the diameter of the aorta expands, linear wall stress increases, which in turn directly increases the risk of spontaneous aortic rupture-an event with extremely poor prognosis for the patient. Thoracic aortic aneurysms (TAAs) involve the ascending aorta most commonly (50%), followed by the descending aorta (40%), whereas arch aneurysms (10%) and thoraco-abdominal aneurysms (10%) occur less often. In 25% of patients with ATAA, concomitant abdominal aortic aneurysm is present. Anatomical distinction is important since the aetiology, ...
The main objective for treating thoracic aortic aneurysm is to prevent it from rupturing. Depending on your aneurysms size and location, your options are medical monitoring or surgery.. Medical Monitoring. This will include regular appointments with your doctor along with frequent imaging tests to check the size of your aneurysm and the rate at which it is growing. If you have other heart or arterial conditions, your doctor may prescribe medication to mitigate symptoms.. It is imperative to discontinue all use of tobacco products after being diagnosed with an aortic aneurysm.. Surgery. Surgery is usually the course of action for anyone with an aneurysm larger than about 5 cm (approximately 2.5 inches). The type of surgical procedure you receive depends on the size and location of your aneurysm and your condition.. The most common operations to repair thoracic aortic aneurysms are:. ...
The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) was initiated in 2006 by the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). GenTAC established a registry of 3706 patients with genetic conditions that may be related to thoracic aortic aneurysms and collected medical data and biologic samples. The study ended in September 2016. Data and samples are available from NHLBI and requests should be made to BioLINCC. See the NHLBI website for more information: https://www.nhlbi.nih.gov/research/resources/gentac ...
The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) was initiated in 2006 by the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). GenTAC established a registry of 3706 patients with genetic conditions that may be related to thoracic aortic aneurysms and collected medical data and biologic samples. The study ended in September 2016. Data and samples are available from NHLBI and requests should be made to BioLINCC. See the NHLBI website for more information: https://www.nhlbi.nih.gov/research/resources/gentac ...
Detailed information on thoracic aortic aneurysms, including description of a thoracic aortic aneurysm, causes, symptoms, diagnosis, treatment, and full-color anatomical illustrations
Aortic aneurysm repair is surgery to fix a weak and bulging section of the aorta. The aorta is the large blood vessel (artery) that carries blood from the heart through the chest and belly to the rest of the body. The doctor used a man-made tube (called a graft) to replace the weak section of your aorta in your chest.. You can expect the cut (incision) in your chest to be sore for a few weeks. If you have stitches or staples in your incision, the doctor will take these out 1 to 3 weeks after surgery.. You will feel more tired than usual for several weeks after surgery. You may be able to do many of your usual activities after 4 to 6 weeks. But you will probably need 2 to 3 months to fully recover.. Some people find that they feel sad or more emotional than usual while they are recovering after this surgery. This may last for up to 6 weeks after surgery. Talk with your doctor if your sadness continues or if you have concerns about how you are feeling. Treatment and other support can help you feel ...
If you have been diagnosed with thoracic aortic aneurysm, you may be a candidate for endovascular stent grafting. Medtronic stent grafts used to treat over 100,000 patients.
Results: Three of the patients presented with rupture and underwent emergency surgery. Two of the patients had type 1 and one had type 4 thoracoabdominal aortic aneurysm. Mortality occurred in three patients, two of which had undergone surgery due to rupture. One patient developed paraparesis in the postoperative period. Conclusions: Thoracoabdominal aortic aneurysm repair is a high-risk procedure requiring good surgical experience, a multidisciplinary approach, good anesthetic management and a cautious intensive care follow up.. Key words: Aortic aneurysm, thoracic; surgery; treatment outcome ...
Background and Goal of Study: Neurologic deficit is a devastating complication of thoracoabdominal aortic aneurysm repair (TAAAR) and is associated with a significant increase in both, morbidity and mortality. The purpose of this study was to identify predictors of neurologic deficit after TAAAR. Materials and Methods: The subjects for this study comprised 449 consecutive patients
Our experience suggest that nonsurgical repair may be an effective therapeutic option for patients with descending thoracic aortic diseases such as aneurysms, pseudoaneurysms, or dissections.. Aneurysm of descending thoracic aorta was the first thoracic aortic disease to be repaired by a stent graft endovascular procedure. Effectively thoracic aneurysm stent graft treatment has the longest and most established long term results.4-6 In the past, our management of descending thoracic aortic aneurysm was medical unless clinical and instrumental signs of rupture were evident and required immediate surgery. At the present time, indications for stent graft treatment are presence of an uncomplicated aneurysm and history of hypertension with chest discomfort, or signs of compression on surrounding organs, as well as a diameter ,6 cm or expansion ,5 mm per year. However, if a patient is considered to be a candidate for stent graft placement, several major factors have to be taken into account. The most ...
1999 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 17, no 3, 268-270 p.Article in journal (Refereed) Published ...
FLAGSTAFF, Ariz. - July 13, 2017 - W. L. Gore & Associates, Inc. (Gore) today announced the first patient implant of the GORE® TAG® Conformable Thoracic Stent Graft with ACTIVE CONTROL System after receiving CE Mark last month. The first implant was performed by Prof. Dr. med. Giovanni Torsello and Dr. med. Martin Austermann at St. Franziskus Hospital, Munster, Germany.. The thoracic endovascular aortic repair (TEVAR) device is the first to feature a new delivery system that provides the physician with controlled, staged deployment. The system optimizes accuracy, angulation, and apposition to treat etiologies of the descending thoracic aorta including aneurysms, transections, and acute and chronic Type B dissections. The new device will be formally launched in European regions later this year.. The GORE® ACTIVE CONTROL System enhances the exceptional conformability of the stent graft; facilitating the optimized wall apposition that the Conformable GORE® TAG® Device is renowned for even in ...
View details of top thoracoabdominal aortic aneurysm hospitals in Bangalore. Get guidance from medical experts to select best thoracoabdominal aortic aneurysm hospital in Bangalore
OBJECTIVE This study was undertaken to define matrix metalloproteinase (MMP) expression in the anterior and posterior wall of descending thoracic aortic aneurysms (TAAs) and correlate it with specific computed tomography (CT) image sites within the descending thoracic aorta. METHODS Serial CT images of patients with TAAs were compared with age- and gender-matched normal descending thoracic aortas at levels T4-T12. The mean circumference of the TAAs was 153 mm (n = 12) and 148 mm (n = 11) at T8 and T10, respectively, compared with 75 mm (n = 12) and 75 mm (n = 10) in controls (P | .001). Aortic tissue was collected from a separate set of eight patients undergoing descending TAA resection (processed | or =12 hours of excision) and six cadavers (processed | or =24 hours of death). Tissue collected between the intercostals arteries was defined as posterior wall, and directly opposite was the anterior wall. MMP-9 and MMP-2 messenger RNA (mRNA) extracted from aortic tissue was analyzed by quantitative real
Over recent years, an improved consensus has been established regarding diagnosis and management of type B aortic dissection (TBAD). Primary conservative medical treatment with antihypertensive agents in combination with close surveillance seems to be justified in TBAD, until complications such as aneurysmal expansion, rupture, or progression of the initial dissection ... read more occur. Several clinical and radiological predictors of aortic growth in uncomplicated TBAD patients have been identified and can be used to select patients at high-risk for aortic enlargement and rupture during follow-up. Those patients might benefit from closer surveillance or early endovascular intervention. Over recent decades, the management of thoracic aortic pathologies has evolved to include endovascular approaches next to conventional open aortic repair. Currently, thoracic endovascular aortic repair (TEVAR) is the preferred approach for patients presenting with complicated TBAD and other thoracic aortic ...
Surgical resection for thoracic aortic aneurysms is generally recommended when the aneurysms size is 5 centimeters or greater, according to Cleveland Clinic. Some surgeons also calculate the risk of...
Aortic aneurysm, familial thoracic (AAT) 3 (AAT3; MIM 610380), AAT4 (MIM 132900), AAT5 (MIM 608967), AAT6 (MIM 611788), AAT7 (MIM 613780), AAT8 (MIM 615436), AAT9 (MIM 616166), SMAD3 related AAT, TGFB2 related AAT and TGFB3 related AAT are dominantly inherited disorders.. AAT5 and AAT3 have been linked to mutations in the transforming growth factor ß receptor type I and II genes (TGFBR1 and TGFBR2). Patients may have aneurysms of the aorta and other arteries. TGFBR2 mutations are currently estimated to be responsible for 5% of familial thoracic aortic aneurysms and dissections (TAAD).. AAT4, thoracic aortic aneurysm and/or dissection with patent ductus arteriosus is caused by mutations in the myosin heavy chain 11 gene (MYH11). It is important to note that not all individuals with myosin heavy chain mutations appear to have dilated aortas. These individuals, though asymptomatic, display a low aortic compliance and distensibility due to a decrease in the elasticity of the aortic wall.. AAT6 is ...
Aortic aneurysm, familial thoracic (AAT) 3 (AAT3; MIM 610380), AAT4 (MIM 132900), AAT5 (MIM 608967), AAT6 (MIM 611788), AAT7 (MIM 613780), AAT8 (MIM 615436), AAT9 (MIM 616166), SMAD3 related AAT, TGFB2 related AAT and TGFB3 related AAT are dominantly inherited disorders.. AAT5 and AAT3 have been linked to mutations in the transforming growth factor ß receptor type I and II genes (TGFBR1 and TGFBR2). Patients may have aneurysms of the aorta and other arteries. TGFBR2 mutations are currently estimated to be responsible for 5% of familial thoracic aortic aneurysms and dissections (TAAD).. AAT4, thoracic aortic aneurysm and/or dissection with patent ductus arteriosus is caused by mutations in the myosin heavy chain 11 gene (MYH11). It is important to note that not all individuals with myosin heavy chain mutations appear to have dilated aortas. These individuals, though asymptomatic, display a low aortic compliance and distensibility due to a decrease in the elasticity of the aortic wall.. AAT6 is ...
thoracic aortic aneurysms are less common than AAA descending thoracic aorta is the second most common location (after ascending aorta) there is a wide range of causes
Thoracic Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Background Compression of the trachea, bronchi, and pulmonary arteries are complications in patients with large thoracic aortic aneurysms. In this case, we report unexpected cardiopulmonary collapse...
Read about the types of thoracic aortic aneurysms and their common symptoms. UPMC offers various treatments and repair surgeries based on your condition.
The first round began with Crawford illustrating a decided speed advantage over Burns, landing a sizzling left hook to midway through the round, while Burns landed a long right and made good use of his jab. Burns may have taken the first round. He is keeping Crawford off-balance. Crawford is not lighting the world on fire, keeping a low workrate and taking a while to warm up to the task, while the busier Burns takes advantage. Crawford did very little in the second stanza.. Having possibly already fallen into a hole, Crawford continued moving slickly, but not nearly moving his hands fast enough in the third. Burns showed a better workrate, giving the impression of being the harder-working fighter. Crawford may have a strategy in mind, but his subdued approach was somewhat mystifying, despite the rounds being close. Close doesnt get it done in Scotland against a domestic world champ, as we have seen before.. In the 4th, Crawford sprung to life with a prolonged barrage that seemed to have Burns ...
Diseases of the thoracic aorta are increasing in prevalence. In the UK, there has been a steady rise in admissions for thoracic aortic dissection (TAD) from 7.2 to 8.8 per 100 000 population over the last decade.1 At the same time, admissions for thoracic aortic aneurysms (TAA) have increased from 4.4 to 9.0 per 100 000. Thoracic aortic disease is deadly; most patients with TAA are likely to die of a complication attributable to their aneurysm, accounting for up to 47 000 deaths annually in the USA.2 TAD affecting the ascending aorta has a 30-day mortality of 25-50%.3 The increase in numbers of patients presenting with disease of the thoracic aorta is predominantly due to an increase in elderly patients, over 75 years of age.1 This means that the upward trend is likely to continue as the population ages, and that these patients are more likely to suffer from multiple additional comorbid conditions, presenting greater challenges for clinicians. In the face of this increasing problem, our ...
TY - JOUR. T1 - Patologia estesa dellaorta toracica. T2 - Trattamento ibrido con la tecnica del frozen elephant trunk. AU - Di Eusanio, Marco. AU - Armaro, Alessandro. AU - Di Marco, Luca. AU - Pacini, Davide. AU - Pantaleo, Antonio. AU - Di Bartolomeo, Roberto. PY - 2011/6. Y1 - 2011/6. N2 - Background. Aneurysms of the aortic arch extending beyond the origin of the left subclavian artery represent a challenging pathology in aortic surgery and, most commonly, are treated with different surgical, endovascular or hybrid two-staged procedures. In 2006, we initiated an intense surgical program with the frozen elephant trunk procedure that, combining together conventional surgery with endovascular techniques, allows single-stage treatment of patients with extended disease of the thoracic aorta. We here describe our surgical technique and the results with the single-stage frozen elephant trunk procedure. Methods. Between January 2007 and August 2010, 87 patients were treated with the frozen elephant ...
Objective:The aim of this study was to investigate outcomes of patients treated with endovascular repair (ER) with the use of fenestrated and branched stent grafts or open surgery (OS) for thoracoabdominal aortic aneurysm (TAAA) in a current series of patients.Methods:All TAAA patients undergoing re
The probability and prediction of relapses were calculated in 186 patients who finished the 2 year follow-up period. Modification of G alpha with myristate can be recapitulated in E. In the several hypogonadotropic syndromes described to date autosomal and X-linked transmission have been implicated in the inheritance of the hypogonadism. The technique of low flow antegrade selective cerebral perfusion through the right brachial artery may be used for a vast majority of aortic aneurysms and dissections requiring arch repair. Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction.. One patient is awaiting repair, and 1 underwent a cavopulmonary shunt. The reproductive deficits of the middle-aged Per mutant females are comparable with those seen in aged wild-type mice. Step baroreflex response in awake patients undergoing carotid viagra without doctor prescription surgery: time- and frequency-domain analysis. Our experiment assessed whether azithromycin inhibits neutrophil accumulation ...
Thoracal, abdominal and thoracoabdominal aortic aneurysm.: There are gender specific differences in the rate of rupture and endovascular treatment of AAA, TAA a
A thoracic stent graft (20) has a tubular bio-compatible graft material body (22) with a lumen therethrough with a proximal end (26) and a distal end (27). There is a sealing stent (28) at the proximal end of the tubular body with an anchoring device which may be a barb (30) affixed to the sealing stent. A distal attachment stent (34) with barbs (36) can be affixed to and extend from the distal end (27) of the graft material body. Intermediate stents (24) are provided along the length of the body. The thoracic stent graft can be in one or two portions.
Japans largest platform for academic e-journals: J-STAGE is a full text database for reviewed academic papers published by Japanese societies
Fenestrated-branched endovascular repair (FB-EVAR) has been widely applied to treat chronic post-dissection thoracoabdominal aortic aneurysms (TAAAs) with favorable outcomes. A recent multicenter experience indicates that outcomes of FB-EVAR for chronic post-dissection are comparable to degenerative TAAAs. Anatomical and technical pitfalls are different than degenerative aneurysms because of true lumen compression, separate target vessel origin from true or false lumen and possible extension of dissection flaps into the renal and mesenteric vessels. This article focuses on planning and sizing FB-EVAR in patients with chronic post-dissection TAAAs.. ...
NOTE: The records of this soldier indicate that his rank is as a Private (unless promoted) until the latter portion of his career when he is referred to as a Trooper (Tpr); the proper designation for the Armoured Corps.. Pte Crawford was granted an eight-day Leave from January 23 to 31, 1916. February 9, 1916, he was attached to Canadian Cavalry Brigade Headquarters for duty. On February 11, 1916, Pte Crawford was attached to the 1st Indian Cavalry Division (Cav Div) for duty as a Military Mounted Policeman (MMP). February 29, 1916, he returned from training with the 1st Indian Cav Div. April 29, 1916, Pte Crawford was taken-on-strength with the Canadian Cavalry Brigade Headquarters (CCB HQ) on transfer from LSH. The Battle of the Somme waged from July 1 to November 16, 1916; Pte Crawford would have been involved in this action. On September 8, 1916, Pte Crawford was "appointed Acting Lance Corporal (A/L/Cpl) without pay". Also on September 8, 1916, he was attached to the Headquarters of the 2nd ...
The biggest news of Wednesdays practice was rather devastating, especially considering the Cowboys sustained so many injuries on defense last year.. Not even an hour into the first real practice, and theyve already lost a significant player for the year.. Tyrone Crawford suffered a torn Achilles injury and will be out for the rest of the season.. Crawford couldnt put any weight on his left foot and was in obvious pain as he rode in the back of the cart, with his dejected face buried in a towel. Even before he was placed on the cart, Crawford was beating the ground with frustration and then tossed his helmet to the ground in disgust when he made it back to the training room area.. The Cowboys were hoping Crawford would be a key player in the defensive-line rotation as a tackle. Crawford played in all 16 games last year, registering 33 tackles and five quarterback pressures.. Last year, the Cowboys lost linebacker Caleb McSurdy to a torn Achilles and then safety Barry Church in Week 3 of the ...
Dr. Pak responded: Not on its own. Aneurysms tend to grow slowly over time: for abdominal aortic aneurysms, about 10% of their diameter per year, for thoracic aneurysms, maybe slightly less. Risk factors for growth include uncontrolled hypertension and |a href="/topics/smoking" track_data="{
Since its introduction by Michael DeBakey in 1956,1 thoracoabdominal aneurysm (TAA) repair generally presents the most technically challenging and controversial issues in vascular surgery. The surgical repair of TAAs is an undertaking that requires substantial preoperative planning and consideration of a wide array of techniques. Each of these techniques has its champions, and several authors have published comparably good results using widely different methods. In this chapter, the common principles that are applicable to all TAA surgery are described. In addition, most of the surgical techniques currently in use to repair these aneurysms are discussed, with emphasis on those that are preferred at the Johns Hopkins Hospital. ...
Suns procedure of total arch replacement using a tetrafurcated graft with stented elephant trunk implantation: analysis of early outcome in 398 patients with acute type A aortic dissection
Aortic diseases, What is a thoracic aortic aneurysm?,How is a thoracic aortic aneurysm diagnosed?Heart Care For You aim of providing comprehensive cardiac care solutions to the patients for Angioplasty Surgery, Bypass surgery, Cardiac surgery, Valve Surg
The major artery carrying blood from the heart to blood vessels throughout the body, the aorta is about one inch in diameter. From the heart, the thoracic aorta extends upward (ascending aorta) before arching (aortic arch) and extending downward through the chest (descending aorta). Along the way, arteries branching from the thoracic aorta supply oxygen-rich blood to the heart muscle, head and neck, arms, and chest. Thoracic surgeons such as Dr. Raissi specialize in repair and replacement techniques for the ascending aorta, aortic arch and descending aorta - those within the chest cavity. When the aorta passes through the diaphragm and into the abdomen, it becomes known as the abdominal aorta and its arteries supply blood to the abdomen and lower extremities. A localized weakness or bulge in the aorta - an aneurysm - can become life-threatening if it ruptures, and victims often have few, if any, noticeable warning signs. Although prolonged high blood pressure and arterial plaque buildup are ...
BACKGROUND: Plasma low-density lipoprotein (LDL)-cholesterol is implicated in aortic aneurysm (AA) and dissection (AD); however, its role in the pathogenesis of AA and AD, a disease with a high mortality rate, is unknown. The existing animal models such as apolipoprotein E-deficient (Apoe-/-) mice cannot reproduce all the conditions of AA/AD, including elevated LDL-cholesterol levels and spontaneous atheroma formation; therefore, a more reliable in vivo model is required. Here, we analyzed angiotensin II-induced mice with combined deficiency of the LDL receptor and the catalytic component of the apolipoprotein B-edisome complex (Ldlr-/-/Apobec1-/-) to understand AA formation and AD occurrence in relation to plasma lipid composition ...
University of Michigan Thoracic Aortic Program is one of the largest in the country, with low mortality rates for even complex thoracic aortic surgeries.
The most important finding in the SMC-specific expressing S100A12 mice was the dilation of ascending aorta at 16 weeks. At 10 weeks of age, no differences were detected in the dimensions of the ascending aortic lumen by high frequency ultrasound, despite substantial changes in the aortic tissue of transgenic mice at this age. Between 10 and 16 weeks of age, the aortas of SMC-specific S100A12 transgenic mice had a striking increase in maximal diameters compared to their non transgenic littermate controls. It would have been helpful to compliment these ultrasound-defined measurements with ex vivo images and measurements of aortas. Curiously, between 10 and 16 weeks of age was the only interval in which the rate of change of aortic dimensions varied between groups. From 16 to 56 weeks of age, the changes in aortic root diameters between the transgenic and non transgenic mice generally paralleled each other in both males and females. Unfortunately, no characteristics of the aortic tissue were ...
The purpose of this study was to compare two non-contrast 2D techniques with the current contrast-enhanced MRI standard 3D technique for the routine assessment of thoracic aortic pathologies. One hund
Sigma-Aldrich offers abstracts and full-text articles by [Ga-Young Suh, Ramin E Beygui, Dominik Fleischmann, Christopher P Cheng].
Learn about the causes, symptoms, diagnosis & treatment of Diseases of the Aorta and Its Branches from the Professional Version of the Merck Manuals.
In addition to his current job leading the Johnny Crawford Dance Orchestra, hes an Army veteran, stage and film actor, former teenage heartthrob and one of the Mouseketeers from the first season of The Mickey Mouse Club in 1955. In the late 80s, a two-year stint as a vocalist for Vince Giordano and the Nighthawks convinced Crawford that he could make a living performing the music from the 20s and 30s that he obsessively loves. Like lots of kids in the 50s, Crawford was nuts about Westerns, but he kept getting overlooked for those parts because he didnt look like the blond, muscular idea of an American kid. [...] a role in what he calls a grade-B movie that was really a grade-C movie, The Courage of Black Beauty, enabled him to learn to ride horses, and that made him more attractive when the next big Western part came along. The Rifleman was originally an episode of The Zane Grey Theater, a TV series produced by former film crooner Dick Powell. Trying to play the music in an
Thoracic aortic aneurysm (TAA) is a life-threatening condition that causes significant short- and long-term mortality due to rupture and dissection. Aneurysm is defined as dilatation of the aorta of greater than 150% of its normal diameter for a given segment.
In 2008, the top priority in our divisions 5-year strategic plan was to become an internationally recognized center of excellence for the endovascular treatment of complex aortic pathology extending from the aortic valve to the external iliac artery. Five components were identified as most critical to achieve this strategic priority: (1) training at centers of excellence in complex endovascular repair; (2) industry partnership to improve access to developing technologies; (3) a fully integrated team approach with one leader involved in all steps of all cases; (4) prospective data collection; and (5) development and implementation of a physician-sponsored investigational device exemption for juxtarenal, pararenal, and thoracoabdominal aneurysms. We have now performed 49 repairs (16 commercially manufactured devices, 33 physician-modified devices) for 3 common iliac, 20 juxtarenal, 9 pararenal, and 17 thoracoabdominal aneurysms, using 142 fenestrations, branches, and scallops. All patients had
BACKGROUND:Aortic dissection (AoD) is a serious complication of thoracic aortic aneurysm (TAA). Relative risk for AoD in relation to TAA etiology, incidence, and pattern after prophylactic TAA surgery are poorly understood.OBJECTIVES:This study sought to determine the incidence, pattern, and relative risk for AoD among patients with genetically associated TAA.METHODS:
An estimated 60,000 Americans are walking around with time bombs in their chests called thoracic aortic aneurysms. At any time, their main chest artery could suddenly burst open, causing massive internal bleeding that is almost always fatal.. Its possible to repair the defect before the artery bursts, but traditional surgery is highly invasive. The operation typically requires an 18-inch incision, a week or two in the hospital and three to six months to recover. There are several major risks, including stroke and paralysis.. At Loyola University Hospital, an increasing number of patients are being treated with a device called a stent graft, which is inserted without opening the chest. Stent graft patients typically go home in a day or two, and recover fully in about two weeks.. At Loyolas Thoracic Aortic Disease Clinic, about 70 percent of patients who undergo surgery for aneurysms in the chest artery are receiving stent grafts rather than open chest surgery. "And as the technology evolves, we ...
February 2005 -- Dr. Syde A. Taheri, MD, is honored to receive an award at the International Symposium of Endovascular Treatment of Aortic Diseases for his invention of the TALENT Thoracic Stent Graft, which is now being produced by MedTronic. Click here to see media coverage about the award and event. Dr. Taheri, along with co-inventor Howard Leonhardt, accepted the award on February 1, 2005, in Rio de Janeiro, Brazil. The symposium specifically highlighted the 10th anniversary of the TALENT device. Click here to see the program for the event, which features the TALENT Thoracic Stent Graft on the cover.. The first clinical research of the TALENT (which stands for Taheri and Leonhardt) Thoracic Stent Graft was conducted at University at Buffalo, New York, in 1991. The device was first used on a human patient with a life-threatening aortic aneurysm in 1995 in ...
US Trends in Thoracic Aneurysm Repair. Karen L. Walker MS Jonathan J. Shuster PHD Thomas M. Beaver MD, MPH Division of Thoracic and Cardiovascular Surgery Division of Biostatistics University of Florida College of Medicine Gainesville, Florida. Objective. Slideshow 154366 by Pat_Xavi
Recent epidemiologic studies have shown lower rates of AAA. Many ascribe this to better chronic treatment of hypertension.. Now Danyi et al have written a review article highlighting the potential for medical therapy to replace some surgery for thoracic aneurysms.. Specifically, they describe molecular mechanisms that may lead to aneurysm formation, and how:. ...
Olympic Champ Chandra Crawford to Focus New Career on Empowerment Through Sport for Young Women. Crawford officially transitions from competitive skiing to operating Fast and Female. - FIS-SKI
Featured Jamal Crawford News. Find breaking news, commentary, and archival information about Jamal Crawford From The latimes (Page 2 of 5)
... - Dr. Tom Crawford has been a member of the Department of Neurology since 1987. He is co-director of the MDA clinic for Neuro...
Dr. Ronald L. Dalman, a vascular surgeon at Stanford Health Care, treats aortic disease, thoracic aortic aneurysm, vascular disease, and more.
My name is Sinead and I am a 5ft 10, forty year old mother of two young children. Nearly four weeks ago I had the ExoVasc operation at the Royal Brompton Hospital in London. My family has a very strong family history on my Fathers side of thoracic aortic aneurysms and dissections. My Father had a successful operation in 2000, involving replacement of the ascending aorta, aortic valve and reimplementation of his coronary arteries. Since then my siblings and I have undergone regular echocardiograms and MRIs. I was found not to have definite Marfans Syndrome but testing concluded I have a Marfans habitus. In June 2014, although my aortic root and ascending aorta did not reach more than 41 mm, my heart consultant at the Royal Berkshire Hospital felt that due to the significant family history I would be suitable for consideration for either an aortic root replacement or an aortic sleeve, ExoVasc, to protect against further dilatation. Having researched both options, the ExoVasc was easily my ...
Congratulations to our own residents Dr. Mario Francispragasam and Dr. Jeff Yoo, as well as Dr. Tong Lam and Dr. Dan Kim for their article in this months CJEM! Read how they diagnosed a thoracic aortic aneurysm using POCUS here: CJEM Case Report
Cindy Crawford, 53, posted on Instagram an ab workout she did at her Malibu home Wednesday morning. The former supermodel continues to stay fit by strength training.
The Morning Sun has asked candidates in contested races to answer a series of questions. They were instructed to limit their responses to 50 words each on the open-form questions. Todays candidates are for Crawford County Commission, District 2. Candidates are listed in alphabetical order.
Visit Healthgrades for information on Dr. Susan Crawford, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Meet doctor Bernard K. Crawford, MD, Thoracic Surgeon, and learn about conditions treated, training, and research at NYU Langone. Read more.
CRAWFORD - Farmhood Fields LLC, a proposed farm-to-table living community owned by Zeke Alenick, is suing the town over the right to build a cattle feed bunk on its Crans Mill Road property.Alenick and Farmhood Fields are suing the town, building department, building inspector and zoning board of appeals, objecting in a complaint filed with the Orange County Clerks Office on Oct. 15 to stop-work orders issued by the town, starting in September, for a structure built in a scenic overlay
For Henri Crockett and Vernon Crawford, the bottom line is the same.Playing a different position is less important than the fact each will play - a lot - Saturday against North Carolina
Study Orbital Muscles flashcards from colin crawford 's Palmer College of Chiropractic-Davenport class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
Study Select muscles of the thorax flashcards from colin crawford 's Palmer College of Chiropractic-Davenport class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
Norm Goldman, Publisher & Editor of Bookpleasures.com Interviews Muriel L. Crawford Author of   Smoking: 201 Reasons to Quit
Charles Crawford created an upcycled bench using IKEA LACK coffee tables found on Craigslist, cut in two. He used expanding insulation foam and latex paint
DentalPlans detailed profile of J Crawford , DDS - Dentist in 84057. View plans, sample savings & pricing, patient reviews & practice information.
Christina Crawford: Get rid of money, switch to a resourced based economy, and learn the best way for humans to live so that we are sustainable in our development.
this is mostly qq about alts. to spend your valor that you get from raiding, you need to grind out reps. which to be honest, is stupid. I get a currency from raiding, and I have to do DAILIES just for the RIGHT to spend it? who thought of this crap? my warlock alt has no desire to do any dailies, I do enough of them on my paladin. but, if I want to spend my valor, I have no choice. rep should only be required for VANITY items. valor items should be on their own vendor, cause if I
[117 Pages Report] Check for Discount on Global Aortic Repair Devices Sales Market Report 2017 report by QYResearch Group. In this report, the global Aortic Repair Devices market is...
Lets start with the guy that I think makes the biggest difference: Dampier. Dampiers arrival originally meant Othellas & Nazrs departure. Not only would the Knicks get rid of a ton of fouls, but they pickup someone that lives inside the paint, shoots at a high percentage, gets to the line fairly often, can rebound, and by my last account can defend. The only thing to not like about the deal is the length of Dampiers contract, which was a big point of contention. If the Knicks can get him for 3 years, without losing another major cog like Sweetney, I would be ecstatic. If I were the Knicks GM, Id even take him for 4 years, but would have to take a long look in the mirror if his agent wanted 5 or more guaranteed years.. If Crawford comes to the Knicks, hell be taking Shandon Andersons place. If Houston isnt healthy, Crawford will be the starting SG. Crawfords FG% (38.6%) is horrible, but his eFG% (45.0%) is more respectable due to the number of 3 pointers he hits (2.1 3PM/G). Crawford ...
01/06/2016. Genomics England (the 100,000 genomes project) includes one condition relevant to Vascular Surgery - Thoracic aneurysm or dissection. If you have any patients suspected of a familial thoracic aneurysm or dissection then they can be entered into the project. Only by having enough patients in the project will a meaningful analysis of the genomics... Read more. ...
Looking over top logs it doesnt seem like horn of valor+CoS outperforms other trinket+CoS in any meaningful way. Do the sims overvalue horn of valor? Is it related to not having a proper sim for BoS?
studies did not adjust for the future development of diabetes during the follow-up period. Therefore, it is still unclear whether the long- ...
It also means the Lakers will stop any attempts to trade power forward Pau Gasol, who cheered Nashs arrival during a Twitcam web chat from Spain early Thursday. Gasol said he believed theres a "lot of juice" left in Nash. "Hes been one of the elite point guards in the league for as long as I can remember," said Gasol, who is practicing with the Spanish Olympic team. "He makes everyone around him better. Hes probably the most unselfish player in the NBA." Nash said he was looking forward to playing with Bryant, Gasol and center Andrew Bynum. "Kobe is still one of the all-time great players in the game," Nash said. "So, I hope he does have the ball in his hands a lot. At the same time, itll take pressure off him if someone else handles the ball and gets him the ball in spots and maybe gets him a few more easy baskets and at the same time maybe creates offense for other guys, so hes not stuck so often having to take on one or two defenders. "Perhaps we can all make each other better because ...
On several occasions, people have asked me what its like to parent a teenage boy. They usually say it through gritted teeth and have a sneer on their face like, "How bad is it really?" Honestly, the thought used to scare me, too. And looking back over my own early teenagehood didnt make me feel any better (I turned it around by age 16, thank the Lord!). But the truth is it just keeps getting better and better! Just like every other stage of your childs life, you figure it out as you go. You make mistakes and swear to fix it on the next kid. But I have to say that teenage boyhood is the MOST FUN for this mama so far. Hes walking in this weird little space between being a kid and being an adult. One minute hes doing flips on the trampoline and the next hes making decisions about what he wants to do with his life and filling out his High School enrollment form accordingly. Hes chosen to take Latin next year, by the way. What in the world?! He constantly amazes me & Ron with his generosity ...
No, it is not life threatening, but it is a condition that has caused and had a severe negative impact on my mental and physical health.
We make our products from raw ingredients, by traditional methods. at Valor Organics we choose to produce a product that works and will not be harmful to the Earth or its waterways.
Para determinar o quanto a avaliação pancreática pode ser útil como valor preditivo da recuperação de eqüinos acometidos por duodeno-jejunite proximal (DJP), foram utilizados 17 equinos, sendo cinco animais...
by Aggarwal, M. M and Ahammed, Z and Alakhverdyants, A. V and Alekseev, I and Alford, J and Anderson, B. D and Arkhipkin, D and Averichev, G. S and Balewski, J and Barnby, L. S and Baumgart, S and Beavis, D. R and Bellwied, R and Betancourt, M. J and Betts, R. R and Bhasin, A and Bhati, A. K and Bichsel, H and Bielcik, J and Bielcikova, J and Biritz, B and Bland, L. C and Bonner, B. E and Bouchet, J and Braidot, E and Brandin, A. V and Bridgeman, A and Bruna, E and Bueltmann, S and Bunzarov, I and Burton, T. P and Cai, X. Z and Caines, H and Calderón de la Barca Sánchez, M and Catu, O and Cebra, D and Cendejas, R and Cervantes, M. C and Chajecki, Z and Chaloupka, P and Chattopadhyay, S and Chen, H. F and Chen, J. H and Chen, J. Y and Cheng, J and Cherney, M and Chikanian, A and Choi, K. E and Christie, W and Chung, P and Clarke, R. F and Codrington, M. J. M and Corliss, R and Cramer, J. G and Crawford, H. J and Das, D and Dash, S and Davila Leyva, A and De Silva, L. C and Debbe, R. R and ...
Mark Crawford , March 1, 2017 Blockchain technology has the potential to streamline insurance transactions, but questions remain about what it can do and how it can best be applied.. ...
The Essex Hall Theatre set for "Stag and Doe" goes dark, lit only by a single ghost light bulb. Written by Mark Crawford, directed by Marc Bondy (BFA 2000), set design by Nancy Perrin. ...
By Elizabeth Crawford The founders of The Little Kernel argue that smaller is better when it comes to ready-to-eat popcorn because they say it is sweeter, crunchier and easier to eat than regular sized popcorn - but will consumers in the US, where bigger is often perceived... ...
Aprenda tudo sobre as estratégias de caixa preta e White-box Testing neste curso. Tópicos abrangem Análise de Valor Fronteira, teste de base de tabela de Decisão e teste de par.
McKellar S.H., Tester D.J., Yagubyan M., Majumdar R., Ackerman M.J., Sundt T.M.. OBJECTIVES: Bicuspid aortic valve is a common condition and is associated with a significantly increased risk of developing thoracic aortic aneurysms and acute aortic dissection. Patient-specific prediction of the risk of developing thoracic aortic aneurysm, however, is imprecise. We hypothesize that genotypic variations in patients with bicuspid aortic valves contribute to this observed variability in aortic phenotype. We, therefore, investigated the potential relationship between mutations in regions of NOTCH1 recently reported to be associated with bicuspid aortic valve and the phenotype of bicuspid aortic valve and thoracic aortic aneurysms in unrelated patients undergoing surgical repair. METHODS: We performed a targeted mutational analysis of NOTCH1 using genomic DNA from 48 unrelated subjects with concomitant bicuspid aortic valve and thoracic aortic aneurysm using denaturing high-performance liquid ...
Previous genetic studies of patients with thoracic aortic aneurysms have identified mutations in several genes involvedin some way with transforming growth factor (TGF)-β signaling: FBN1 (encoding fibrillin-1, causing Marfan syndrome), TGFBR1 and TGFBR2 (encoding transforming growth factor-β receptors I and II, causing Loeys-Dietz syndrome), and SMAD3 (encoding Mothers against decapentaplegic homolog 3, causing aneurysms-osteoarthritis syndrome). Two groups (Boileau et al, Lindsay et al) sought to identify additional genes responsible for familial thoracic aortic aneurysms. They also sought to explain an apparent paradox: mutations in the aforementioned genes that would be predicted to result in reduced activity of the TGF-β pathwayappear to cause vasculopathy via increased TGF-β signaling.. ...
The suitable treatment strategy for acute descending aortic dissection has long been a matter of debate and continues to be a challenge [1]. High mortality rates in surgical treatment (25-50%) of complicated acute type B dissections, directed surgeons to search for other treatment modalities. Implementation of endovascular techniques has provided new therapeutic options [5]. Initial series and subsequent multicenter trials demonstrated technical feasibility and a low rate of complications even in high-risk patients with acute type B dissection.. However, treatment of acute aortic dissections by endovascular grafting itself carries some risks. Leakage can occur in approximately 25% of patients. Rarely, the stent graft may not plug the aortic wall adequate and may dislocate. In 8% of patients embolic material may originate from an atherosclerotic basis and corrupt the blood flow of the spinal cord, leading to paraplegia. There is furthermore the risk for abdominal malperfusion. In this situation ...
A 46-year-old man was given a diagnosis of hypertension about 20 years previously. At age 41, aortitis syndrome was diagnosed, with descending thoracic aortic aneurysm and the coarctation of abdominal aorta by CT scan. He then underwent surgery to replace the descending thoracic aortic aneurysm and right axillo-bifemoral bypass. Recently, a thoraco-abdominal aortic aneurysm was pointed out at the distal site of the graft and, he was referred to our institute. We occluded the distal end of the aneurysm using an endoluminal occlusion stent graft. Today, in most cases of aortopathy associated with aortitis syndrome, surgical replacement of the aneurysms and extra-anatomical bypass is performed. An endovascular stent graft treatment combined with extra-anatomical bypass could be useful for various aortic disorders ...
However, along with the positive economic impact of gaming, there or are the inevitable negative motivational effects research of the problem and thoracic aortic aneurysm resulting ease in loss of productivity, suicide, trouble breathing, bankruptcy, and vulgar crime. Also, the fda has regularly asked the maker of controlled drug, meda pharmaceuticals inc., to add and a neatly boxed warning to its label and to develop a psychological medicine guide that
Current management and outcome of chronic type B aortic dissection: results with open and endovascular repair since the advent of thoracic endografting
TY - JOUR. T1 - Operative and Midterm Outcomes of the Fenestrated Anaconda Stent-Graft in the Endovascular Treatment of Juxtarenal, Suprarenal, and Type IV Thoracoabdominal Aortic Aneurysms. AU - Kotelis, Drosos. AU - Schleimer, Karina. AU - Foldenauer, Christina. AU - Jalaie, Houman. AU - Grommes, Jochen. AU - Jacobs, Michael J.. AU - Kalder, Johannes. PY - 2016/12. Y1 - 2016/12. KW - abdominal aortic aneurysm. KW - endoleak. KW - endovascular aneurysm repair. KW - fenestrated stent-graft. KW - juxtarenal aneurysm. KW - mortality. KW - reintervention. KW - suprarenal aneurysm. KW - thoracoabdominal aortic aneurysm. U2 - 10.1177/1526602816667281. DO - 10.1177/1526602816667281. M3 - Article. VL - 23. SP - 930. EP - 935. JO - Journal of Endovascular Therapy. JF - Journal of Endovascular Therapy. SN - 1526-6028. IS - 6. ER - ...
Open aortic surgery Endovascular Aneurysm Repair (EVAR). Aortic dissection. Open aortic surgery Thoracic Endovascular Aneurysm ... August 1994). "Design of the abdominal aortic Aneurysm Detection and Management Study. ADAM VA Cooperative Study Group". J Vasc ... "The Multicentre Aneurysm Screening Study (MASS) into the effect of abdominal aortic aneurysm screening on mortality in men: a ... July 1996). "Intraoperative heparinisation, blood loss and myocardial infarction during aortic aneurysm surgery: a Joint ...
"Treatment of Thoracic Aortic Aneurysms." Presented St. John's Cardiovascular Institute Annual Symposium. Loughridge, B.P. 2000 ... American College of Cardiology Society of Thoracic Surgeons Southern Thoracic Surgical Association Fellow, International ... In 1971-72 Loughridge moved to Syracuse, New York where he served as a Senior Resident in Thoracic Surgery at the State ... Loughridge was the Chief of Thoracic and Cardiovascular Surgery at two of Tulsa's main hospitals, St. John Hospital and at St. ...
He died of thoracic aortic aneurysm. Private Investment in Latin America: Renegotiating the Bargain (1975) Joseph J. Jova, 75; ...
SLC6A4 Aortic aneurysm, familial thoracic 4; 132900; MYH11 Aortic aneurysm, familial thoracic 6; 611788; ACTA2 Aortic valve ... AGA Asphyxiating thoracic dystrophy 2; 611263; IFT80 Asphyxiating thoracic dystrophy 3; 613091; DYNC2H1 Asthma and nasal polyps ... aneurysms, and muscle cramps; 611773; COL4A1 Aniridia; 106210; PAX6 Anonychia congenita; 206800; RSPO4 Anterior segment ... MAPT Supravalvar aortic stenosis; 185500; ELN Surfactant metabolism dysfunction, pulmonary, 1; 265120; SFTPB Surfactant ...
"Early Recognition of Acute Thoracic Aortic Dissection and Aneurysm". World Journal of Emergency Surgery. 8: 47. doi:10.1186/ ...
It may cause aortic regurgitation, thoracic aortic dissection, aneurysm and rupture. It is often associated with connective ... In tertiary syphilis the aortic root becomes so dilated that the aortic valve becomes incompetent and cor bovinum results. The ... Annuloaortic ectasia is a dilation of the proximal ascending aorta and aortic annulus. ... https://radiopaedia.org/articles/annulo-aortic-ectasia https://books.google.de/books?id=yE8tBAAAQBAJ&pg=PA556&lpg=PA556&dq= ...
"Effect of extended cross-clamp time during thoracoabdominal aortic aneurysm repair". The Annals of Thoracic Surgery. The ... Certain surgeries for cerebral aneurysms or aortic arch defects require that blood circulation be stopped while repairs are ... European Journal of Cardio-Thoracic Surgery. Elsevier Science. 4 (7): 390-3. doi:10.1016/1010-7940(90)90048-5. PMID 2397132. " ... Society of Thoracic Surgeons. 66 (4): 1204-8. doi:10.1016/S0003-4975(98)00781-4. PMID 9800807. Replantation at eMedicine Safar ...
Forsch died suddenly from a thoracic aortic aneurysm on November 3, 2011. Less than a week before his death, he threw out the ...
4) Aortic disease: Aortic atherosclerosis, thoracic aortic aneurysm, and abdominal aortic aneurysm. An individual's risk for ... abdominal aortic aneurysm (AAA) diabetes mellitus Chronic Kidney Disease The Framingham/ATP III criteria were used to estimate ...
Motor evoked potentials have also been used in surgery for Thoracic aortic aneurysm. Intraoperative monitoring is used to : to ... For example, during any surgery on the thoracic or cervical spinal column, there is some risk to the spinal cord. Since the ... EEG electroencephalography is used for monitoring of cerebral function in neurovascular cases (cerebral aneurysms, carotid ...
Escribano JF, Carnés J, Crespo MA, Antón RF (2006). "Ortner's syndrome and endoluminal treatment of a thoracic aortic aneurysm ... thoracic aortic aneurysms, an enlarged pulmonary artery and aberrant subclavian artery syndrome have been reported compressing ...
"Selective cerebral perfusion during operation for aneurysms of the aortic arch: a reassessment". The Annals of Thoracic Surgery ... "Selective cerebral perfusion during operation for aneurysms of the aortic arch: a reassessment". The Annals of Thoracic Surgery ... "Selective cerebral perfusion during operation for aneurysms of the aortic arch: a reassessment". The Annals of Thoracic Surgery ...
... lead to thoracic aortic aneurysms and dissections". Nature Genetics. 39 (12): 1488-1493. doi:10.1038/ng.2007.6. PMID 17994018. ... such as thoracic aortic aneurysm and ischaemic heart disease.[165] The α-actin found in smooth muscles is also an interesting ... It has been noted that the MYH11 mutation could be responsible for at least 14% of hereditary thoracic aortic aneurisms ... along with thoracic aortic disease". American Journal of Human Genetics. 84 (5): 617-627. doi:10.1016/j.ajhg.2009.04.007. PMC ...
"Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms". J Thorac Cardiovasc Surg ... A deficiency can be associated with bicuspid aortic valve. There is evidence that activated Notch 1 and Notch 3 promote ...
GeneReviews: Thoracic Aortic Aneurysms and Aortic Dissections. 維基共享資源中相關的多媒體資源:主動脈剝離. ... Acute aortic syndrome)[1][2],同時會有嘔吐、冒汗、頭重腳輕等症狀[2]。因為無法提供足夠血液到其他器官,也會有像中風或腸繫膜缺血等症狀[2]。主動脈剝離後,因為無法提供心臟足夠
Certain mutations in the MYLK gene are associated with thoracic aortic aneurysms or thoracic aortic dissections. This disease ... A disease characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. It ... "Mutations in myosin light chain kinase cause familial aortic dissections". American Journal of Human Genetics. 87 (5): 701-7. ...
"Selective cerebral perfusion during operation for aneurysms of the aortic arch: a reassessment". The Annals of Thoracic Surgery ...
"Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms". The Journal of Thoracic ... A deficiency can be associated with bicuspid aortic valve. There is evidence that activated Notch 1 and Notch 3 promote ...
The legislation became known as the Screening Abdominal Aortic Aneurysms Very Efficiently (SAAAVE) Act of 2004 (HR 4626). Lin ... Lin, P.H. (2008). "Endovascular repair of traumatic thoracic aortic injuries: a critical appraisal". Asian Cardiovasc Thorac ... His writing and speaking have focused on a range of subjects including endovascular treatment of aortic aneurysms, venous ... Lin, P.H. (2009). "Hypogastric artery preservation during endovascular aortic aneurysm repair: is it important?". Seminar of ...
... and thoracic aortic aneurysm. A study of patients with SCSFLS demonstrated no mutations in this gene. Minor features of Marfan ... It may also run in families and be associated with aortic aneurysms and joint hypermobility. Up to two thirds of those ... spinal cerebrospinal fluid leak as a cause of coma after craniotomy for clipping of an unruptured intracranial aneurysm". ...
For aneurysms of the thoracic aorta, thoracic endovascular aortic repair (TEVAR) has become a valid alternative to open repair ... The conventional approach for treatment of aortic valve stenosis is surgical replacement of the aortic valve. This procedure ... Endovascular stenting versus open surgery for thoracic aortic disease: systematic review and metaanalysis of the results. ... The Journal of Thoracic and Cardiovascular Surgery, Vol.131, No.1, (January 2006), pp. 163-171, PII S0022-5223(05)01370-X ...
GeneReviews/NIH/NCBI/UW entry on Thoracic Aortic Aneurysms and Aortic Dissections GeneReviews/NCBI/NIH/UW entry on Loeys-Dietz ... Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDS, LDAS). TGF beta receptor 1 has been ...
"A splenic injury due to ruptured abdominal aortic aneurysm." J Cardiovasc Surg (Torino) 2007;48:528 Gur O, Canbaz S, Karaca OG ... Enver Duran (born June 19, 1945 in Bursa) is a Turkish medic specialising in thoracic-cardiovascular surgery, a university ... Between the years 1985-1990 he worked as an associated professor in Gülhane Military Medical Academy Thoracic-Cardiovascular ... After he completed his General Surgery Specialization education in 1977-1980, he became a Specialist in Thoracic-Cardiovascular ...
A Novel Locus for Familial Thoracic Aortic Aneurysms and Dissection Mapped to 15q24-26 (TAAD3): Locus Specific Phenotypes for ... Analysis of multigenerational families with thoracic aortic aneurysms and dissections due to TGFBR1 or TGFBR2 mutations. J Med ... Familial aggregation of both aortic and cerebral aneurysms: evidence for a common genetic basis in a subset of families. J ... along with thoracic aortic disease. Am J. Hum Genet. 84(5):617-617, 2009. Epub 2009 Apr 30. Tran-Fadulu V, Pannu H, Kim DH, ...
"Chronic Traumatic Aneurysm of the Thoracic Aorta". New England Journal of Medicine. 257 (19): 913-918. doi:10.1056/ ... Aortic rupture can also be caused by non-traumatic mechanisms, particularly abdominal aortic aneurysm rupture. ... Traumatic aortic rupture, also called traumatic aortic disruption or transection, is a condition in which the aorta, the ... Aortic transection[edit]. Traumatic aortic rupture is treated with surgery. However, morbidity and mortality rates for surgical ...
Aneurysm / dissection /. pseudoaneurysm. *torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm ...
An aneurysm is an abnormal widening or ballooning of a portion of an artery due to weakness in the wall of the blood vessel. ... A thoracic aortic aneurysm occurs in the part of the bodys largest artery (the aorta) that passes through the chest. ... Most thoracic aortic aneurysms are detected on imaging tests performed for other reasons. These tests include chest x-ray, ... The most common cause of a thoracic aortic aneurysm is hardening of the arteries. This condition is more common in people with ...
Thoracic aneurysm may occur in three parts of the thoracic aorta: the ascending aorta, the descending aorta or the aortic arch ... Thoracic Aortic Aneurysm The aorta is the artery that carries oxygen-rich blood away from the heart and on to other arteries ... A thoracic aortic aneurysm occurs when a "balloon" forms in a weakened area of the aorta wall within the chest cavity. The ... A minor thoracic aortic aneurysm may have little effect on an individual, but can also be life-threatening and fatal if it ...
By definition, an aneurysm is a localized or diffuse dilation of an artery with a diameter at least 50% greater than the normal ... encoded search term (Thoracic Aortic Aneurysm) and Thoracic Aortic Aneurysm What to Read Next on Medscape. Related Conditions ... Aneurysmal degeneration that occurs in the thoracic aorta is termed a thoracic aortic aneurysm (TAA). Aneurysms that coexist in ... Endovascular treatment of thoracic aortic aneurysms: results of the phase II multicenter trial of the GORE TAG thoracic ...
A thoracic aortic aneurysm (TAA) is a bulging in the part of the aorta that passes through the chest. These are stories of ... And thats when the doctor saw it - a large aneurysm in Sandys aorta right above his heart.. More ...
A thoracic aortic aneurysm (TAA) is a bulging in the part of the aorta that passes through the chest. These are stories of ... And thats when the doctor saw it - a large aneurysm in Sandys aorta right above his heart.. More ... The Society of Thoracic Surgeons: Aortic Aneurysms * Medline Plus: Thoracic Aortic Aneurysms ...
Screening for thoracic aortic aneurysms. Conditions that cause a thoracic aortic aneurysm may run in families. Because of this ... Endovascular repair for thoracic aortic aneurysm. Endovascular repair for thoracic aortic aneurysm. In endovascular repair, ... Open chest surgery for thoracic aortic aneurysm. Open chest surgery for thoracic aortic aneurysm. Open chest surgery to repair ... Ascending aortic root aneurysm procedure. Ascending aortic root aneurysm procedure. An ascending aortic root aneurysm procedure ...
... repair is indicated for an asymptomatic thoracic aortic aneurysm with a root diameter greater than 5 cm. ... This patients echocardiogram demonstrates a thoracic aortic aneurysm with an aortic root diameter of 6.2 cm, which requires ... In patients with Marfan syndrome, repair is indicated for an asymptomatic thoracic aortic aneurysm with a root diameter greater ... Aortic root dilatation is typical of the disease, and the murmur heard on physical examination represents aortic regurgitation ...
A thoracic aortic aneurysm (TAA) is a bulging in the part of the aorta that passes through the chest. We develop endovascular ... Some patients with a thoracic aortic aneurysm also have an abdominal aortic aneurysm. ... A thoracic aortic aneurysm is considered serious. The bulge in your thoracic aorta can become weak, and the force of normal ... Most people with a thoracic aortic aneurysm do not have any symptoms. Often, the aneurysms grow slowly and go unnoticed. Many ...
The Talent™ Thoracic Stent Graft System is intended for the endovascular repair of fusiform aneurysms and saccular aneurysms/ ... The Talent® Thoracic Stent Graft System is intended for the endovascular repair of fusiform aneurysms and saccular aneurysms/ ... Valiant Thoracic Stent Graft with the Captivia Delivery System. Indications. The Valiant® Thoracic Stent Graft with the ... Key anatomic elements that may affect successful exclusion of the aneurysm include severe neck angulation, short aortic neck(s ...
The thoracic stent graft can be in one or two portions. ... A thoracic stent graft (20) has a tubular bio-compatible graft ... 28, 2002, entitled "Thoracic Aortic Aneurysm Stent Graft" discloses stent grafts that are useful in treating aortic aneurysms ... However, for an aneurysm that develops in the thoracic arch of the aorta, stent grafts are needed that are deployable to extend ... Reduced-strain extra-vascular ring for treating aortic aneurysm. US9526638. 2 Feb 2012. 27 Dic 2016. Endospan Ltd.. Implantable ...
Figure 2: Computed tomography scan of the chest showing a thoracic aortic aneurysm (4 × 6 cm, arrow) with a heterogeneous mass ... Hemoptysis caused by erosion of thoracic aortic aneurysm. Dongmei Sun and Sanjay Mehta ...
Read about the types of thoracic aortic aneurysms and their common symptoms. UPMC offers various treatments and repair ... Thoracic Aortic Aneurysm​. Descending Thoracic and Thoracoabdominal Aortic Aneurysms. A descending thoracic aortic aneurysm is ... Thoracic aortic aneurysm symptoms. Descending thoracic aortic aneurysms (TAAs) and thoracoabdominal aortic aneurysms (TAAAs) ... Learn More About Thoracic and Thoracoabdominal Aortic Aneurysms. From the Society for Vascular Surgery. *Thoracic Aortic ...
Endovascular stent grafting is a minimally invasive procedure used to prevent a thoracic aneurysm from bursting. Medtronic ... Endovascular stent grafting, or endovascular aortic repair (EVAR), is a newer form of treatment for thoracic aortic aneurysms ... Thoracic aortic aneurysms can weaken the aorta, your bodys largest blood vessel. This can develop into a potentially serious ... The endovascular stent is placed inside of your thoracic aorta to help reinforce the blood vessel and prevent the aneurysm from ...
Thoracic aneurysms are less common than abdominal ones. In some individuals with a thoracic aortic aneurysm, an underlying ... A thoracic aortic aneurysm (TAA) is a ballooning of a portion of the aorta, the largest artery in the human body. Aneurysms are ... Thoracic aortic aneurysms (TAAs) are considered high risk for rupture if they are located below the aortic arch and greater ... Aneurysms of the descending thoracic aorta are the most common of the thoracic aneurysms, followed by the ascending segment and ...
... it may require repair by open surgery or endovascular aneurysm repair (EVAR). Medtronic develops stent graft devices for EVAR. ... Not all thoracic aortic aneurysms need surgery. If yours is small, your doctor may decide to wait and watch carefully to see if ... Thats why we try to make all our therapies, including our stent graft for treating thoracic aortic aneurysms, as minimally ... If the doctor feels there is a risk that the aneurysm will burst, he or she may recommend one of two aneurysm repair methods - ...
New to this forum. Diagnosed from two different type tests an echo and then three months(july 2012) later a CT Scan; measurements went from 4.9 to 4.7...
If you have been diagnosed with thoracic aortic aneurysm, you may be a candidate for endovascular stent grafting. Medtronic ... You may not be a good candidate if you have a very large thoracic aortic aneurysm, irregularly shaped thoracic aneurysms or ... An alternative to open surgery for thoracic aortic aneurysm repair is a minimally invasive procedure called thoracic ... If you are considering surgery to repair a thoracic aortic aneurysm, you have been told by your doctor that you have an ...
If you have been diagnosed with thoracic aortic aneurysm, you may be a candidate for endovascular stent grafting. Medtronic ... You may not be a good candidate if you have a very large thoracic aortic aneurysm, irregularly shaped thoracic aneurysms or ... If you are considering surgery to repair a thoracic aortic aneurysm, you have been told by your doctor that you have an ... Currently, the standard treatment for a thoracic aortic aneurysm is open surgery. In this procedure, the section of the vessel ...
... risk of aneurysm rupture with endovascular stent grafting that is slightly higher than that of open-chest aortic aneurysm ... Your aneurysm may not have the right shape, or it may be too close to other organs. Your doctor or vascular surgeon will help ... Rupture of the aneurysm or aorta. To monitor these possible complications, your doctor will ask you to schedule periodic visits ...
About a month after Sandys thoracic aortic aneurysm was diagnosed, it was repaired with a Medtronic Talent™ Thoracic Stent ... And thats when the doctor saw it - a large descending thoracic aneurysm in Sandys aorta right above his heart. ... Sandys doctor showed him the aneurysm on the x-ray and they discussed how best to treat it. The aneurysm had to be repaired ... The options were either open surgery to replace the damaged part of the aorta, or endovascular aneurysm repair (EVAR) with a ...
Medtronic offers the Talent Thoracic stent for this condition ... stent graft after treatment for thoracic aortic aneurysm. ... As a person with a thoracic aortic aneurysm, you may have an increased risk for clogging of the arteries and heart disease. ... and may encourage the growth of aneurysms. If you smoke, then you should stop, and if you dont smoke, stay away from second- ... The Society of Thoracic Surgeons: Aortic Aneurysms * Medline Plus: Thoracic Aortic Aneurysms ...
Medtronic offers treatment options for thoracic aortic aneurysms. ... recovery from endovascular stent graft treatment of thoracic ... The Society of Thoracic Surgeons: Aortic Aneurysms * Medline Plus: Thoracic Aortic Aneurysms ...
Thoracic Aortic Aneurysms. Thoracic aneurysms may involve one or more aortic segments (aortic root, ascending aorta, arch, or ... Abdominal Aortic Aneurysms. Abdominal aortic aneurysms are much more common than thoracic aortic aneurysms. Age is an important ... Bicuspid Aortic Valve Many cases of ascending thoracic aortic aneurysms are associated with an underlying bicuspid aortic valve ... Familial Thoracic Aortic Aneurysm Syndrome Cystic medial degeneration is also seen in patients with ascending thoracic aortic ...
Aneurysm. Aortic Aneurysm. Aortic Aneurysm, Thoracic. Vascular Diseases. Cardiovascular Diseases. Aortic Diseases. ... Genetics Home Reference related topics: Familial thoracic aortic aneurysm and dissection MedlinePlus related topics: Aneurysms ... Clinical Study of Thoracic Aortic Aneurysm Exclusion (Valiant). The safety and scientific validity of this study is the ... Thoracic aortic aneurysms. In: Haimovicis Vascular Surgery, 4th ed, H Haimovici, E Ascer, LH Hollier, DE Strandness, and JB ...
What is an abdominal aortic aneurysm? (0:04) 2. What is a thoracic aneurysm? (0:22) 3. What causes aneurysms? (0:46) 4. How is ... What are the symptoms of a thoracic aneurysm? (1:26) 6. What are the symptoms of an abdominal aneurysm? (1:50) 7. Who is at ... Surgery Christopher Abularrage and Associate Professor of Surgery James Black discuss abdominal and thoracic aortic aneurysms. ... When are aneurysms treated? (4:09) 11. What are the tests to determine treatment for aneurysms? (4:35) ...
  • Your team will work together to develop a personalized treatment plan that takes into consideration the size of the aneurysm and how fast it's growing as well as your personal needs and lifestyle. (uhhospitals.org)
  • blood clots may form at the site and dislodge, increasing the chance of stroke Increase in the size of the aneurysm, causing it to press on other organs, which may cause pain. (wikipedia.org)
  • The characteristic pathology of an aneurysm is characterized by progressive vessel wall dilation, promoted by dying vascular smooth muscle cells and limited proliferation, as well as impaired synthesis and degradation of extracellular matrix components, which at least partially is the result of transmural inflammation and its disruptive effect on vessel wall homeostasis. (nih.gov)
  • Fbn C1039G/+ / βarr2 −/− mice displayed delayed aortic root dilation compared with Fbn C1039G/+ mice. (physiology.org)
  • An aneurysm is a localized dilation or a bulge in the blood vessel due to weakening of the vessel wall. (epainassist.com)
  • BAV helical and high velocity outflow patterns are consistent with aortic dilation hemodynamics seen in those with tricuspid aortic valves. (wikipedia.org)
  • For this reason the left, right and posterior aortic sinuses are also called left-coronary, right-coronary and non-coronary sinuses. (wikipedia.org)
  • Questions regarding family history of sudden cardiac death or history of aortic aneurysm is also included. (cancertherapyadvisor.com)
  • We herein report a rare case of cardiac and abdominal aortic inflammatory pseudotumors (IPTs). (nih.gov)
  • Fellows also gain experience in perioperative medical (anesthetic) management of the cardiac patient, including management of intra-aortic balloon pumps (IABP) and ventricular assist devices (VAD), post-operative ICU care, blood transfusion medicine, electrophysiology, and transthoracic echocardiography. (wikipedia.org)
  • Hans-Joachim Schäfers (born 28 August 1957 in Lünen) is a German surgeon, as well as cardiac, thoracic, and vascular surgeon and university professor. (wikipedia.org)
  • Complications after aneurysm stenting include damage to the blood vessels supplying the leg, which may require another operation. (medlineplus.gov)
  • Aneurysm presentation may range from life-threatening complications of hypovolemic shock to being found incidentally on X-ray. (wikipedia.org)