Aorta: The main trunk of the systemic arteries.Aorta, Thoracic: The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.Aorta, Abdominal: The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.Aortic Diseases: Pathological processes involving any part of the AORTA.Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.Aortography: Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.Muscle, Smooth, Vascular: The nonstriated involuntary muscle tissue of blood vessels.Aortic Aneurysm, Thoracic: An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.Aneurysm, Dissecting: Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.Endothelium, Vascular: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.Blood Vessel Prosthesis Implantation: Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Aortic Rupture: The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.Vasodilation: The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.Vasoconstriction: The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.Phenylephrine: An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.Vasoconstrictor Agents: Drugs used to cause constriction of the blood vessels.Aortitis: Inflammation of the wall of the AORTA.Aneurysm, Infected: Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Vasodilator Agents: Drugs used to cause dilation of the blood vessels.ElastinAtherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.Polyethylene Terephthalates: Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.Arteries: The vessels carrying blood away from the heart.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Dilatation, Pathologic: The condition of an anatomical structure's being dilated beyond normal dimensions.Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.Diet, Atherogenic: A diet that contributes to the development and acceleration of ATHEROGENESIS.Acetylcholine: A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.Venae Cavae: The inferior and superior venae cavae.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Rats, Inbred WKY: A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR).Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Aneurysm, False: Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.Iliac Artery: Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.Rats, Inbred SHR: A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Aortic Valve: The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.Cholesterol, Dietary: Cholesterol present in food, especially in animal products.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Apolipoproteins E: A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Nitroprusside: A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Nitric Oxide Synthase Type III: A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.Endothelium: A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Echocardiography, Transesophageal: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Takayasu Arteritis: A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.Nitric Oxide Synthase: An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.Pulmonary Artery: The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.Elasticity: Resistance and recovery from distortion of shape.Subclavian Artery: Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.Angiotensin II: An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.Constriction: The act of constricting.Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.Cyclic GMP: Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)Mesenteric Arteries: Arteries which arise from the abdominal aorta and distribute to most of the intestines.Elastic Tissue: Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.Brachiocephalic Trunk: The first and largest artery branching from the aortic arch. It distributes blood to the right side of the head and neck and to the right arm.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Mice, Inbred C57BLCalcinosis: Pathologic deposition of calcium salts in tissues.Femoral Artery: The main artery of the thigh, a continuation of the external iliac artery.NG-Nitroarginine Methyl Ester: A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Vascular Surgical Procedures: Operative procedures for the treatment of vascular disorders.Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).Cholesterol: The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.Blood Vessels: Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Aortic Arch Syndromes: Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.Methylene Blue: A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Carotid Arteries: Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.Renal Artery: A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Rats, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.Tunica Intima: The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid: A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Celiac Artery: The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.Myocytes, Smooth Muscle: Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Angiography: Radiography of blood vessels after injection of a contrast medium.Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.Paraplegia: Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.Pulsatile Flow: Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.Ductus Arteriosus: A fetal blood vessel connecting the pulmonary artery with the descending aorta.Circulatory Arrest, Deep Hypothermia Induced: A technique to arrest the flow of blood by lowering BODY TEMPERATURE to about 20 degrees Centigrade, usually achieved by infusing chilled perfusate. The technique provides a bloodless surgical field for complex surgeries.Endovascular Procedures: Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Spinal Cord Ischemia: Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.Thoracotomy: Surgical incision into the chest wall.Desmosine: A rare amino acid found in elastin, formed by condensation of four molecules of lysine into a pyridinium ring.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Stress, Mechanical: A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Receptors, Thromboxane: Cell surface proteins that bind THROMBOXANES with high affinity and trigger intracellular changes influencing the behavior of cells. Some thromboxane receptors act via the inositol phosphate and diacylglycerol second messenger systems.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Coronary Vessels: The veins and arteries of the HEART.Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.Tunica Media: The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.Sinus of Valsalva: The dilatation of the aortic wall behind each of the cusps of the aortic valve.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.Mesenteric Artery, Superior: A large vessel supplying the whole length of the small intestine except the superior part of the duodenum. It also supplies the cecum and the ascending part of the colon and about half the transverse part of the colon. It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra.Regional Blood Flow: The flow of BLOOD through or around an organ or region of the body.Receptors, Adrenergic, alpha-1: A subclass of alpha-adrenergic receptors that mediate contraction of SMOOTH MUSCLE in a variety of tissues such as ARTERIOLES; VEINS; and the UTERUS. They are usually found on postsynaptic membranes and signal through GQ-G11 G-PROTEINS.Desoxycorticosterone: A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE.Adrenergic alpha-Antagonists: Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Epoprostenol: A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).Vena Cava, Inferior: The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Nitroarginine: An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)Czechoslovakia: Created as a republic in 1918 by Czechs and Slovaks from territories formerly part of the Austro-Hungarian Empire. The country split into the Czech Republic and Slovakia 1 January 1993.

A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. (1/4396)

Microdeletions of chromosome 22q11 are the most common genetic defects associated with cardiac and craniofacial anomalies in humans. A screen for mouse genes dependent on dHAND, a transcription factor implicated in neural crest development, identified Ufd1, which maps to human 22q11 and encodes a protein involved in degradation of ubiquitinated proteins. Mouse Ufd1 was specifically expressed in most tissues affected in patients with 22q11 deletion syndrome. The human UFD1L gene was deleted in all 182 patients studied with 22q11 deletion, and a smaller deletion of approximately 20 kilobases that removed exons 1 to 3 of UFD1L was found in one individual with features typical of 22q11 deletion syndrome. These data suggest that UFD1L haploinsufficiency contributes to the congenital heart and craniofacial defects seen in 22q11 deletion.  (+info)

The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation. (2/4396)

1. Arachidonic acid (0.01-1 microM) induced relaxation of precontracted rings of rabbit saphenous vein, which was counteracted by contraction at concentrations higher than 1 microM. Concentrations higher than 1 microM were required to induce dose-dependent contraction of vena cava and thoracic aorta from the same animals. 2. Pretreatment with a TP receptor antagonist (GR32191B or SQ29548, 3 microM) potentiated the relaxant effect in the saphenous vein, revealed a vasorelaxant component in the vena cava response and did not affect the response of the aorta. 3. Removal of the endothelium from the venous rings, caused a 10 fold rightward shift in the concentration-relaxation curves to arachidonic acid. Whether or not the endothelium was present, the arachidonic acid-induced relaxations were prevented by indomethacin (10 microM) pretreatment. 4. In the saphenous vein, PGE2 was respectively a 50 and 100 fold more potent relaxant prostaglandin than PGI2 and PGD2. Pretreatment with the EP4 receptor antagonist, AH23848B, shifted the concentration-relaxation curves of this tissue to arachidonic acid in a dose-dependent manner. 5. In the presence of 1 microM arachidonic acid, venous rings produced 8-10 fold more PGE2 than did aorta whereas 6keto-PGF1alpha and TXB2 productions remained comparable. 6. Intact rings of saphenous vein relaxed in response to A23187. Pretreatment with L-NAME (100 microM) or indomethacin (10 microM) reduced this response by 50% whereas concomitant pretreatment totally suppressed it. After endothelium removal, the remaining relaxing response to A23187 was prevented by indomethacin but not affected by L-NAME. 7. We conclude that stimulation of the cyclo-oxygenase pathway by arachidonic acid induced endothelium-dependent, PGE2/EP4 mediated relaxation of the rabbit saphenous vein. This process might participate in the A23187-induced relaxation of the saphenous vein and account for a relaxing component in the response of the vena cava to arachidonic acid. It was not observed in thoracic aorta because of the lack of a vasodilatory receptor and/or the poorer ability of this tissue than veins to produce PGE2.  (+info)

Enantioselective inhibition of the biotransformation and pharmacological actions of isoidide dinitrate by diphenyleneiodonium sulphate. (3/4396)

1. We have shown previously that the D- and L- enantiomers of isoidide dinitrate (D-IIDN and L-IIDN) exhibit a potency difference for relaxation and cyclic GMP accumulation in isolated rat aorta and that this is related to preferential biotransformation of the more potent enantiomer (D-IIDN). The objective of the current study was to examine the effect of the flavoprotein inhibitor, diphenyleneiodonium sulphate (DPI), on the enantioselectivity of IIDN action. 2. In isolated rat aortic strip preparations, exposure to 0.3 microM DPI resulted in a 3.6 fold increase in the EC50 value for D-IIDN-induced relaxation, but had no effect on L-IIDN-induced relaxation. 3. Incubation of aortic strips with 2 microM D- or L-IIDN for 5 min resulted in significantly more D-isoidide mononitrate formed (5.0 +/- 1.5 pmol mg protein(-1)) than L-isoidide mononitrate (2.1 +/- 0.7 pmol mg protein(-1)) and this difference was abolished by pretreatment of tissues with 0.3 microM DPI. DPI had no effect on glutathione S-transferase (GST) activity or GSH-dependent biotransformation of D- or L-IIDN in the 105,000 x g supernatant fraction of rat aorta. 4. Consistent with both the relaxation and biotransformation data, treatment of tissues with 0.3 microM DPI significantly inhibited D-IIDN-induced cyclic GMP accumulation, but had no effect on L-IIDN-induced cyclic GMP accumulation. 5. In the intact animal, 2 mg kg(-1) DPI significantly inhibited the pharmacokinetic and haemodynamic properties of D-IIDN, but had no effect L-IIDN. 6. These data suggest that the basis for the potency difference for relaxation by the two enantiomers is preferential biotransformation of D-IIDN to NO, by an enzyme that is inhibited by DPI. Given that DPI binds to and inhibits NADPH-cytochrome P450 reductase, the data are consistent with a role for the cytochromes P450-NADPH-cytochrome P450 reductase system in this enantioselective biotransformation process.  (+info)

Effect of acute and long-term treatment with 17-beta-estradiol on the vasomotor responses in the rat aorta. (4/4396)

1. This study sought to evaluate whether the effects of acute and long-term treatment with 17-beta-estradiol on the vasomotor responses in rat aortic rings are mediated through the same mechanism. 2. Ovariectomized rats were treated daily with either 17-beta-estradiol-3-benzoate (100 microg kg(-1)) or vehicle for 1 week. 3. The effect of long-term 17-beta-estradiol treatment on the responses to cumulative doses of phenylephrine, 5-HT, calcium, potassium and 17-beta-estradiol was determined in aortic rings. In the same rings, the effect of acute exposure to 17-beta-estradiol (5 and 10 microM) on the dose response curves for phenylephrine, 5-HT, calcium, potassium and acetylcholine were estimated. The measurements were made in rings with and without intact endothelium. The tone-related basal release of nitric oxide (NO) was measured in rings with intact endothelium. 4. Long-term 17-beta-estradiol treatment reduced the maximum developed contraction to all contracting agents studied. This effect was abolished in endothelium denuded vessels. Acute 17-beta-estradiol treatment also reduced maximal contraction. This effect, however, was independent of the endothelium. 5. Long-term 17-beta-estradiol treatment significantly increased the ability of the rings to dilate in response to acetylcholine whereas acute exposure to 17-beta-estradiol had no effect. The tone-related release of NO was significantly increased after long-term exposure to 17-beta-estradiol. 6. In conclusion, this study indicate that the acute and long-term effects of 17-beta-estradiol in the rat aorta are mediated through different mechanisms. The long-term effect is mediated through the endothelium most likely by increasing NO release. In contrast, the acute effect of 17-beta-estradiol seems to be through an effect on the vascular smooth muscle cells.  (+info)

Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. (5/4396)

1. The mechanisms of the sustained vasodilator actions of corticotrophin-releasing factor (CRF) and sauvagine (SVG) were studied using rings of endothelium de-nuded rat thoracic aorta (RTA) and the isolated perfused rat superior mesenteric arterial vasculature (SMA). 2. SVG was approximately 50 fold more potent than CRF on RTA (EC40: 0.9 +/- 0.2 and 44 +/- 9 nM respectively, P < 0.05), and approximately 10 fold more active in the perfused SMA (ED40: 0.05 +/- 0.02 and 0.6 +/- 0.1 nmol respectively, P < 0.05). Single bolus injections of CRF (100 pmol) or SVG (15 pmol) in the perfused SMA caused reductions in perfusion pressure of 23 +/- 1 and 24 +/- 2% that lasted more than 20 min. 3. Removal of the endothelium in the perfused SMA with deoxycholic acid attenuated the vasodilatation and revealed two phases to the response; a short lasting direct action, and a sustained phase which was fully inhibited. 4. Inhibition of nitric oxide synthase with L-NAME (100 microM) L-NMMA (100 microM) or 2-ethyl-2-thiopseudourea (ETPU, 100 microM) had similar effects on the vasodilator responses to CRF as removal of the endothelium, suggesting a pivotal role for nitric oxide. However the selective guanylate cyclase inhibitor 1H-[l,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ, 10 microM) did not affect the response to CRF. 5. High potassium (60 mM) completely inhibited the vasodilator response to CRF in the perfused SMA, indicating a role for K channels in this response. 6. Compared to other vasodilator agents acting via the release of NO, the actions of CRF and SVG are strikingly long-lasting, suggesting a novel mechanism of prolonged activation of nitric oxide synthase.  (+info)

Protective effect of dietary tomato against endothelial dysfunction in hypercholesterolemic mice. (6/4396)

The effects of dietary ingestion of tomato were studied in mice that had been made hypercholesterolemic by feeding atherogenic diets. Mice which had been fed on the atherogenic diet without tomato for 4 months had significantly increased plasma lipid peroxide, and the vaso-relaxing activity in the aorta induced by acetylcholine (ACh) was harmed when compared with mice fed on a common commercial diet. On the other hand, mice which had been fed on the atherogenic diet containing 20% (w/w) lyophilized powder of tomato showed less increase in the plasma lipid peroxide level, and ACh-induced vaso-relaxation was maintained at the same level as that in normal mice. These results indicate that tomato has a preventive effect on atherosclerosis by protecting plasma lipids from oxidation.  (+info)

Effects of docosahexaenoic and eicosapentaenoic acid on lipid metabolism, eicosanoid production, platelet aggregation and atherosclerosis in hypercholesterolemic rats. (7/4396)

Exogenously hypercholesterolemic (ExHC) rats were fed on an atherogenic diet supplemented with 1% each of either ethyl ester docosahexaenoic acid [EE-DHA, 22:6(n-3)], ethyl ester eicosapentaenoic acid [EE-EPA, 20:5(n-3)] or safflower oil (SO) for 6 months. The rats fed on the diets containing EE-EPA or EE-DHA, compared with those fed on SO, had lower serum cholesterol and triacylglycerol levels, less aggregation of platelets and slower progress of intimal thickening in the ascending aorta. Relative to the SO-fed rats, both of the (n-3) fatty acid-fed rats had a significantly reduced proportion of arachidonic acid in the platelet and aortic phospholipids, and lower production of thromboxane A2 by platelets and of prostacyclin by the aorta. These results suggest that EPA and DHA are similarly involved in preventing atherosclerosis development by reducing hypercholesterolemia and modifying the platelet functions.  (+info)

Modulation of temperature-induced tone by vasoconstrictor agents. (8/4396)

One of the primary cardiovascular adjustments to hyperthermia is a sympathetically mediated increase in vascular resistance in the viscera. Nonneural factors such as a change in vascular tone or reactivity may also contribute to this response. Therefore, the aim of this study was to determine whether vascular smooth muscle tone is altered during heating to physiologically relevant temperatures >37 degrees C. Gradually increasing bath temperature from 37 degrees C (normothermia) to 43 degrees C (severe hyperthermia) produced graded contractions in vascular ring segments from rat mesenteric arteries and thoracic aortae. In untreated rings these contractions were relatively small, whereas hyperthermia elicited near-maximal increases in tension when rings were constricted with phenylephrine or KCl before heating. In phenylephrine-treated mesenteric arterial rings, the contractile responses to heating were markedly attenuated by the Ca2+ channel antagonists nifedipine and diltiazem. Diltiazem also blocked the contractile responses to heating in thoracic aortic rings. These results demonstrate that hyperthermia has a limited effect on tension generation in rat vascular smooth muscle in the absence of vascular tone. However, in the presence of agonist-induced tone, tension generation during heating is markedly enhanced and dependent on extracellular Ca2+. In conclusion, these data suggest that local regulation of vascular tone can contribute to the hemodynamic adjustments to hyperthermia.  (+info)

The descending thoracic aorta arises from the aortic arch just after the origin of the left subclavian artery, at the inferior border of the fourth thoracic vertebrae. This point of transition is termed the aortic isthmus. In adults, the average diameter of the descending thoracic aorta is 2.8 cm in men and 2.6 cm in women.2 This narrows as it descends into the abdomen. It terminates as it enters the abdomen via the diaphragmatic aortic hiatus, at the 12th intercostal space. The thoracic aorta descends in the posterior mediastinum to the left of the vertebral column and gradually shifts to the midline at the aortic hiatus. It is surrounded by the thoracic aortic plexus. Anteriorly, the left pulmonary hilum crosses with the left main bronchus and left pulmonary artery being closely associated. Continuing inferiorly, the esophagus, pericardium, and diaphragm are also situated at the anterior border of the thoracic aorta. As the thoracic aorta descends, the esophagus crosses anteriorly and then ...
BioAssay record AID 602900 submitted by ChEMBL: Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM after 10 to 60 mins.
BioAssay record AID 568587 submitted by ChEMBL: Vasodilatory activity in Sprague-Dawley rat thoracic aorta smooth muscle assessed as inhibition of phenylephrine-induced vasoconstriction.
Transmural concentration profiles of 125I-albumin in vivo were measured across the normal and balloon catheter-deendothelialized rabbit descending thoracic aorta as a function of time following intravenous injection. A tracer was injected 5 or 60 minutes after deendothelialization, and the animals were sacrificed after circulation times of 10, 30 or 60 minutes. The aorta was immediately excised and frozen flat between glass slides. Samples were serially sectioned parallel to the intimal surface in a refrigerated microtome, washed with trichloroacetic acid (TCA), and counted. Relative tissue concentration profiles of TCA-precipitable radioactivity from the media of control animals showed entry from both luminal and adventitial sides, as previously found with conscious normal rabbits, but spatial gradients at both luminal and medial-adventitial borders were less steep. Relative concentration levels in ballooned animals were 10- to 40-fold higher than in controls, and the profiles were flatter. ...
New pharmacotherapies are required to improve vessel graft protection and prevent vasoconstriction and spasm in CABG surgery. Previously we have studied adenosine (A) and lidocaine (L) relaxation in rat aortic rings, and reported a possible crosstalk between L relaxation and adenosine A(2a) receptor inhibition. The aim of the present study was to examine the effect of AL combination compared to A and L alone on relaxation in intact and denuded rat aortic rings and in guinea-pig pressurized mesenteric arterial segments. Aortic rings were harvested from Sprague-Dawley rats and equilibrated in an organ bath containing modified Krebs-Henseleit (KH) solution, pH 7.4, 37 degrees C. Rings were pre-contracted sub-maximally with 0.3 mu M norepinephrine, and the effects of increasing AL, A or L (up to 1.0 mM) were examined in intact and denuded rings. Mesenteric artery segments were isolated from guinea-pigs and mounted in an arteriograph containing KH solution and pressurised to 60 mmHg. Arteries were ...
Hey all. Im not here often as my kiddos issue was minor (ASD) and diagnosed at 6 months. It was just a waiting game to see if it would close until her 4 year check, which just occurred on 9/6. At that time, she had a complete echocardiogram, which had not been done since she was diagnosed with the ASD at 6 months - reason being is her pediatric cardio wasnt going to intervene until she hit 40 lbs., so he didnt think it was necessary. She always had an EKG at her check-ups, and that was it. Anywho, she had the echo and needless to say, my very hyper daughter was not the best patient. They seemed to take forever. They were taking shots off and on for about 1.5 hours. Tech called in cardiologist who was trying to get a shot, but having trouble as well. Finally, cardiologist tells us that the ASD is closed. I say - wait, even *I* can still here her murmur clear as day. She says, We need to talk. We go in and she draws a picture and explains in too simple terms that Lauren has a right
Transesophageal MRI of human thoracic aortae demonstrate the feasibility of the technique in healthy volunteers (Fig. 2A)and among patients with aortic atherosclerosis (Fig. 2B-D). Figure 2C, Dshows the corresponding TEMRI and TEE images of the distal aortic arch in a 77-year-old male patient with remote stroke, depicting heterogeneous atherosclerotic thickening, and this illustrates differences in circumferential plaque extent by the two methods. Figure 2Eis a longitudinal slice through the descending thoracic aorta and a portion of the arch of a normal subject, demonstrating the nonuniform SNR of the device (9,12). The SNR decreases linearly with radial distance from the probe, but substantially maintains its SNR along much of its length. In practical terms, this property allows TEMRI at multiple longitudinal locations over ∼20 cm without the need for repositioning the device.. Maximum and minimum WTs were 3.5 ± 1.2 mm and 1.2 ± 0.8 mm by TEE, and 3.3 ± 1.5 mm and 1.0 ± 0.7 mm by TEMRI, ...
Endovascular repair of the thoracic aorta has been adopted as the first-line therapy for much pathology. Initial results from the early-generation endografts have highlighted the potential of this technique. Newer-generation endografts have now been introduced into clinical practice and careful assessment of their performance should be mandatory. This study describes the initial experience with the Valiant endograft and makes comparisons with similar series documenting previous-generation endografts. Data were retrospectively collected on 180 patients treated with the Valiant endograft at seven European centers between March 2005 and October 2006. The patient cohort consisted of 66 patients with thoracic aneurysms, 22 with thoracoabdominal aneurysms, 19 with an acute aortic syndrome, 52 with aneurysmal degeneration of a chronic dissection, and 21 patients with traumatic aortic transection. The overall 30-day mortality for the series was 7.2%, with a stroke rate of 3.8% and a paraplegia rate of 3.3%.
Published in: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (ISSN: 1078-5884), vol. 26, num. 2, p. 195-204 ...
With the advent of helical CT, the capability of noninvasive imaging of the thoracic aorta has been enhanced considerably. In this article, we describe the potential of helical CT using dual-slice technology to evaluate thoracic aortic diseases such
TY - JOUR. T1 - Treatment of dissecting aneurysms of the descending thoracic aorta.. AU - Juanteguy, J. M.. AU - Wilder, R. J.. PY - 1970/8. Y1 - 1970/8. UR - http://www.scopus.com/inward/record.url?scp=0014836896&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0014836896&partnerID=8YFLogxK. M3 - Article. C2 - 5450420. AN - SCOPUS:0014836896. VL - 36. SP - 493. EP - 498. JO - American Surgeon. JF - American Surgeon. SN - 0003-1348. IS - 8. ER - ...
FIGURE 1. (A) Schematic setup of the stereo-vision system to focus on a specimen, (B) specimen images taken by each camera, and (C) the reconstructed positions of markers affixed to the specimen in the 3D coordinate system. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.] - Longitudinal differences in the mechanical properties of the thoracic aorta depend on circumferential regions.
The thoracic aorta begins at the level of vertebra T5 and continues through to the diaphragm at the level of T12, initially traveling within the mediastinum to the left of the
CT - Angiograms - Thoracic aorta angiogram is a way of looking at the blood vessels in different parts of your body. Learn more about this procedure.
The aorta originates from the left ventricle of the heart. It ends in the abdomen where it branches into the two common iliac arteries. The aorta has five separate segments. The descending aorta begins at the arch of the aorta (where it loops over the heart to begin its descent).
02UX4KZ ICD-10 PCS Code descriptor cic Aorta, Ascending/Arch with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
Xinmai Medical (688016) In-depth report: Domestic aorta and prolonged vascular intervention faucet. Report Summary Xinmai Xinmai Medical is currently the leading domestic manufacturer of aortic and vascular interventional products, with rich products and leading market share.. The company developed and launched the worlds first split-type stent graft in the field of thoracic aorta stent grafts. In the field of abdominal aortic stent grafts, although there is still a gap with imported products, it is gradually upgraded and is expected to achieve import substitution.. The layout of distal vascular interventional devices is extensive and rich. Drug replacement balloons have been applied for marketing, and the market potential has broken through.. The company has rich research reserves, continuous high-intensity research and development, and expansion of innovation capabilities. It is a leader in aortic intervention and interventional vascular 苏州桑拿网 disease segmentation.. The domestic ...
Abe and associates reported the trends in the early outcomes of surgical repair for acute type A aortic dissection in 11,843 patients from the Japan Cardiovascular Surgery Database between 2008 and 2015. Operative mortality was 9.5% and 30-day mortality was 7.6%. The number of surgically treated cases increased by 45% during the interval ...
Does anyone know what anatomical structure does the Thoracic Aorta become the ABD aorta? Also @ what structure does the common iliac become the Fem-po
In the previous studies, extensive accumulation and slower elimination of radioactivity from the eyeball and thoracic aorta were observed when 14C-YM758 was orally administered to nonalbino rats and/or albino rats. In albino rats, the plasma concentrations of the unchanged drug were detected only at 0.5 and 1 h, and the area under the curve extrapolated to 1 h ratio between the plasma concentrations of radioactivity and the unchanged drug was estimated to be 17.7%, indicating the existence of YM758 metabolites in rat plasma (Umehara et al., 2008f). In rat plasma, R1 (YM-385462), R2 (YM-385463), R3 (YM-385459), R4 (YM-252124), R9 (YM-234903), R10 and R19 (YM-396944) were detected as YM758 metabolites from radio-HPLC analyses (Fig. 4) (N. Nakada, Y. Susaki, T. Yokota, K. I. Umehara, T. Sonoda, E. Nakamura, T. Usui, T. Iwatsubo, and H. Kamimura, manuscript submitted for publication; Umehara et al., 2009a,b). Considering the previous findings and discussion on YM758 metabolites detected in rat ...
This study was designed to determine whether the endothelium-derived relaxing factor induced by acetylcholine (1 microM) in rabbit thoracic aorta inhibits agonist-induced calcium mobilization, specifically calcium influx. Force generated in rings of rabbit thoracic aorta by norepinephrine (1 microM) was measured under isometric conditions. At the appropriate time during 1 microM acetylcholine-induced relaxation of 1 microM norepinephrine-contracted rabbit thoracic aorta, the rings were pulse-labelled with calcium-45 to measure calcium influx. When measured in this fashion, 1 microM acetylcholine decreased the 1 microM norepinephrine-induced increase in calcium influx. This effect was eliminated by removal of the endothelium and by atropine (1 microM), but not by indomethacin (14 microM). Acetylcholine (1 microM) also blocked the 60 mM potassium-chloride-induced increase in calcium influx without dramatically affecting force. The phasic contraction produced by norepinephrine (1 microM) with 2 mM ...
METHODS AND RESULTS Normal or hypercholesterolemic rabbits received intravenous L-arginine (10 mg/kg/min) or vehicle for 70 minutes. Subsequently, animals were killed, thoracic aortas were harvested, and vascular rings were studied in vitro. Rings were contracted by norepinephrine and relaxed by acetylcholine chloride or sodium nitroprusside. Vasorelaxation was quantified by determining the maximal response (expressed as percent relaxation of the contraction) and the ED50 (dose of drug inducing 50% relaxation; expressed as -log M). In vessels from hypercholesterolemic animals receiving vehicle, there was a fivefold rightward shift in sensitivity to acetylcholine compared with normal animals (p = 0.05, n = 5 in each group). In vessels from hypercholesterolemic animals, L-arginine augmented the maximal response to acetylcholine (83 +/- 16% versus 60 +/- 15%, p = 0.04 versus vehicle) and increased the sensitivity to acetylcholine (ED50 value: 6.7 +/- 0.2 versus 6.2 +/- 0.2, p less than 0.05 versus ...
PURPOSE: Traumatic rupture of the thoracic aorta secondary to blunt chest trauma is a life-threatening emergency and a common cause of death, usually following violent collisions. The objective of this retrospective report was to evaluate the efficacy of endovascular treatment of thoracic aortic disruptions with a single commercially available stent-graft.. METHODS: Nine men (mean age 29.5 years) were admitted to our institution between January 2003 and January 2006 due to blunt aortic trauma following violent motor vehicle collisions. Plain chest radiography, spiral computed tomography, aortography, and transesophageal echocardiography were used for diagnostic purposes in all cases. All patients were diagnosed with contained extramural thoracic aortic hematomas, secondary to aortic disruption. One patient was also diagnosed with a traumatic thoracic aortic dissection, secondary to blunt trauma. All subjects were poor surgical candidates, due to major injuries such as multiple bone fractures, ...
Patients involved in high-energy blunt trauma involving rapid deceleration are at significant risk for blunt aortic injury. The majority of blunt aortic injuries are due to motor vehicle collision. In the United States, blunt aortic injury is the sec
Right aortic arch with aberrant left subclavian artery (RAA/aLSCA) is a rare aortic arch anomaly. The clinical association of aLSCA stenosis with RAA/aLSCA has not yet been fully elucidated. The aim of this study was to investigate the diagnosis, incidence, management and outcome of aLSCA stenosis in infants with prenatally diagnosed RAA/aLSCA. Ten fetuses who were diagnosed as having RAA/aLSCA in Kyushu University Hospital between January 2011 and December 2014 were enrolled. The maternal and child medical records were reviewed to investigate sex, gestational age at the fetal diagnosis, gestational age and body weight at birth, the findings of computed tomography (CT), Doppler ultrasonography of the vertebral artery and angiography, and the complications and outcomes of aLSCA stenosis ...
Sigma-Aldrich offers abstracts and full-text articles by [Ga-Young Suh, Ramin E Beygui, Dominik Fleischmann, Christopher P Cheng].
This study was designed to determine whether the relaxant effect of apigenin was endothelium dependent and to examine the possible antiproliferative effect of apigenin. Apigenin relaxed the phenylephrine-precontracted endothelium-intact aortic rings with IC50 value of 3.7+/-0.5 muM and removal of a functional endothelium significantly attenuated this relaxation (IC50 = 8.2+/-0.9 muM). However, apigenin did not affect the 0.1 muM phorbol 12,13-dibutyrate-induced contraction (IC50 = 34.6 +/- 1.2 muM) within the concentration range that relaxed the phenylephrine-contracted arteries, suggesting that apigenin did not influence protein kinase C-mediated contractile mechanisms in rat aorta. Pretreatment of apigenin significantly potentiated the relaxant effect of acetylcholine on phenylephrine-induced contraction. Pretreatment with N-G-nitro-L-arginine methyl ester (L-NAME) or methylene blue reduced the relaxant effect of apigenin. Apigenin (10 muM) increased the guanosine 3′,5′-cyclic ...
The major artery carrying blood from the heart to blood vessels throughout the body, the aorta is about one inch in diameter. From the heart, the thoracic aorta extends upward (ascending aorta) before arching (aortic arch) and extending downward through the chest (descending aorta). Along the way, arteries branching from the thoracic aorta supply oxygen-rich blood to the heart muscle, head and neck, arms, and chest. Thoracic surgeons such as Dr. Raissi specialize in repair and replacement techniques for the ascending aorta, aortic arch and descending aorta - those within the chest cavity. When the aorta passes through the diaphragm and into the abdomen, it becomes known as the abdominal aorta and its arteries supply blood to the abdomen and lower extremities. A localized weakness or bulge in the aorta - an aneurysm - can become life-threatening if it ruptures, and victims often have few, if any, noticeable warning signs. Although prolonged high blood pressure and arterial plaque buildup are ...
Definition of esophageal branches of the thoracic aorta. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
Background: Large aortic arch plaques are associated with ischemic stroke. Carotid intima-media thickness (CIMT) is a marker of subclinical atherosclerosis and a strong predictor of cardiovascular disease and stroke. The association between CIMT and aortic arch plaques has been studied in patients with strokes, but not in the general population. The aim of this study was to investigate this association in an elderly asymptomatic cohort and to assess the possibility of using CIMT to predict the presence or absence of large aortic arch plaques. ...
Abnormally stiffened arteries are present in individuals with diabetes and are associated with an increase in cardiovascular events, LV afterload, and exercise intolerance (1,4,9). In this study, we sought to determine if individuals with IFG exhibited abnormal stiffening of the arterial tree (including the proximal thoracic aorta) that in studies of individuals with diabetes is associated independently with adverse cardiovascular events. There are two important findings in this study: Total vascular stiffness is worse in subjects with IFG compared with those with NFG. This finding is true regardless of age, sex, ethnicity, or other factors associated with abnormal vascular stiffening (Table 2; Fig. 2). After adjustment for factors known to influence vascular stiffness, proximal thoracic aortic stiffness and LV mass are similar in individuals with IFG and NFG (Figs. 3 and 4). In patients with diabetes, however, both proximal thoracic aortic stiffness and LV mass are elevated (Figs. 3 and ...
A new potent, selective and p.o. active serotonergic [5-hydroxytryptamine (5-HT2)] receptor antagonist, SR 46349B [trans, 4-([3Z)3-(2-dimethylaminoethyl)oxyimino-3(2-flurophenyl++ +)propen-1-yl]phenol hemifumarate) has been characterized by a series of "in vitro" and "in vivo" methods. Based upon binding studies with 5-HT2 receptors in rat brain cortical membranes and blockade of 5-HT-induced contractions in isolated tissues (rabbit thoracic aorta, rat jugular vein, rat caudal artery, rat uterus and guinea pig trachea), SR 46349B showed high affinity for 5-HT2 receptors. Furthermore, SR 46349B displayed moderate affinity for the 5-HT1C receptor and had no affinity for the other 5-HT1 subclass (5-HT1A, 5-HT1B or 5-HT1D), dopamine (D1 or D2), "alpha" adrenergic (alpha-1 or alpha-2), sodium and calcium channel and histamine (H1) receptors. It did not interact with histamine (H1), alpha-1 adrenergic and 5-HT3 receptors in smooth muscle preparations. No inhibition of the uptake of norepinephrine, ...
TY - JOUR. T1 - Management of arch hypoplasia after successful coarctation repair. AU - DeLeon, Maryann M.. AU - DeLeon, Serafin Y.. AU - Quinones, Jose A.. AU - Roughneen, Patrick. AU - Magliato, Kathy E.. AU - Vitullo, Dolores A.. AU - Cetta, Frank. AU - Bell, Timothy J.. AU - Fisher, Elizabeth A.. PY - 1997. Y1 - 1997. N2 - Background. Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a somewhat hypoplastic arch to grow or from clamp injury at the time of the initial repair, or from both causes. Because of mediastinal adhesions and minimal collateral circulation, use of extraanatomic bypass grafts appears to be the preferred approach. Methods. Six children or young adults presented with arch obstruction over a 3-year period. Their mean age was 13.5 ± 4 years, and the mean interval from the time of the initial repair was 10 ± 4 years. The mean age of the patients at the time of the initial repair was 3.2 ± 5 years. ...
Purpose of Review The purpose of this manuscript is to review the surgical techniques of aortic arch repair, imaging techniques for evaluating the pre- and post-operative aortic arch, and both normal...
Diseases of the cardiovascular system are predicted to be the leading worldwide cause of death by 2030.1,2 Cardiovascular diseases (CVDs) are characterised as diseases of lifestyle, associated with a Western diet and low levels of physical activity. However, ischaemic heart disease and other non-communicable diseases are likely to be major contributors to mortality in sub-Saharan Africa.2. Forms of these diseases (once associated with ageing3) are common in younger individuals; atherosclerotic lesions, aneurysms and strokes have been reported in children and young adults.4-6 Fatty dots and streaks, which may represent the early stages of atherosclerosis, have been found in the aortas of babies and infants.6. Risk factors in the increasing prevalence of CVD include cigarette smoking, high-fat diet, high cholesterol levels, obesity, diabetes, hypertension and HIV infection.1,4,7 Antiretroviral treatment for HIV-positive individuals also increases the risk of developing CVD.8. Certain ...
enlarged aorta - MedHelps enlarged aorta Center for Information, Symptoms, Resources, Treatments and Tools for enlarged aorta. Find enlarged aorta information, treatments for enlarged aorta and enlarged aorta symptoms.
The current study has demonstrated significant regional variation in access to treatment, the organization of clinical services, and mortality for patients with TAD in England. An analysis of HES data demonstrated that the variation in the proportion of TAD patients treated within 6 months of diagnosis ranged from 7.6% to 31.5% among counties and remained statistically significant after adjustment for potential confounders, including comorbidity, deprivation, disease severity, and population density. Regional variation was not associated with differences in mortality rates for patients that received treatment, but was associated with differences in mortality in those that did not receive treatment, implying that inequity in access to care has important effects on outcome. The analysis of NASCA data indicated wide regional variation in the volume and complexity of TAD cases undertaken in English cardiac centers. Centers undertaking higher volumes were more likely to treat more‐complex disease ...
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The speeds at which an aortic laceration can occur in an auto crash vary greatly. Doctors use the term Delta V when determining forces causing aortic tears.
Penyakit Aneurisma Aorta - Aneurisma aorta atau aneurisme aorta merupakan pembengkakan pembuluh aorta perut atau pembesaran aorta, pembuluh darah utama yang menyalurkan darah ke tubuh pada level abdomen. Baca Juga [more…] ...
noun the descending part of the aorta that branches into the thoracic and abdominal aortae • Hypernyms: ↑aorta * * * noun : the part of the aorta from the arch to its bifurcation that passes downward in the thoracic and abdominal cavities
Oxygenated blood begins its course down the chest through the thoracic aorta, a major blood vessel with branches that serve the chest muscles and lungs. This becomes the abdominal aorta.
Relaxation of Rat Aorta by Farrerol Correlates with Potency to Reduce Intracellular Calcium of VSMCs. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Researchers investigate the role of arterial stiffness in memory decline in older adults. A flexible aorta may be key to maintaining cognitive ability.
Study Flashcards On Ascending Aorta at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Learn more about Aortic Coarctation -- Adult at Grand Strand Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at TriStar Centennial Parthenon Pavilion DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
I was diagnosed in 2012 with ascending aorta dialation of 4.1 cm. In 2013 no change. Finally went back to dr in 2017 and echo showed 4.3 cm. 2 months later dr made me have a chest scan which read 4.5 cm. which is correct? Echo or scan? Dr wants […]
Survival Technology - SonoSims new aorta and IVC real-patient scanning cases are available in the Aorta/IVC Core Clinical Module
Dont miss out on the latest Cta Abd Aorta Bi Iliofem Coupon right HERE. Pick one of our tested and updated vouchers - 100% verified and working ...
I live in the UK and my best friend and I have turned 50 this year. He has been diagnosed with an enlarged Aorta and been told that something will need to be done within the next five years. He seems...
The revision #92494 of the page named "Aorta VI" does not exist. This is usually caused by following an outdated history link to a page that has been deleted. Details can be found in the deletion log. ...
The aorta of mice involves certain challenges, such as resolution and partial volume effects. As all the animals have been treated similarly, the problems are
... - Vas de sange important care preia sangele pompat de inima si din care pleaca vase mari catre intreg organismul. Principala artera a organismului, formandu-se de la baza ventriculului stang si distribuind
What makes the Aorta Kukri blade great, is its ability to make deep penetrating cuts while piercing with ease as well as its ability to be moved quickly.
Saya (56 tahun) didiagnosis dokter mengidap penyakit aneurisma aorta bagian abdomen. Dari jantung kearah ginjal terjadi pembengkakan. Dokter menyarankan untuk
НИИ атеросклероза: научные исследования, публикации сотрудников института (abstracts, full-text.), дискуссионный клуб, посвященный вопросам механизмов атерогенеза.
Program:Aorta betegs gei9.00- 9.20- Prenatalis diagnosztika. Dr. Lad nyi Anik Bicuspidalis aorta billenty 9.30-9.50 Bicuspidalis aorta billenty - plasztika feln tt korban- seb szeti lehet s gek, eredm nyek- Dr. Sz...
This article was originally based on an entry from a public domain edition of Grays Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant. ...
Originally Published: 03/25/18 at 08:15am Another week, less answers! Going to doctors and getting tests done has turned into a full time job for me, and I would really prefer my actual job :) This week I had an MRI, and saw a Pain doctor and I feel like I have less information then I…
Sabesin, S. M. Proc. Soc. exp. Biol. Med., 112. 1963, 667. Saxen, E., L. Saxen, P. Grоnrооs. Aorta pathol. microbiol. scand., 44, 1958, 318. Saxen, L., E. ...
വിവരങ്ങൾ ക്രിയേറ്റീവ് കോമൺസ് ആട്രിബ്യൂഷൻ-ഷെയർഎലൈക്ക് അനുമതിപത്ര പ്രകാരം ലഭ്യമാണ്; മേൽ നിബന്ധനകൾ ഉണ്ടായേക്കാം. കൂടുതൽ വിവരങ്ങൾക്ക് ഉപയോഗനിബന്ധനകൾ കാണുക ...
In this study using a newly developed CNT-based micro-CT with cardiac and respiratory gating, we have successfully quantified calcification in the aortic arch plaques of living mice. CNT-based sources are able to achieve a 10 ms or better temporal resolution, not directly achievable using conventional thermionic sources. As a result, we were able to gate cardiac and respiratory motion in a straightforward manner, allowing simplified animal handling without the need for intubation.. Heart contraction causes movement of the vascular wall and thereby motion blur in the acquired image.9 In addition, because the R-wave interval at 600 beats per minute is 100 ms, errors of pulse control ,5 to 10 ms could result in significant additional blur of structures. One of the key advantages of our CNT-based micro-CT system is the ability to control the x-ray pulses to at least a microsecond level. Although in vivo imaging of arch calcification has already been reported in B6-apoE KO mice using a conventional ...
Objectives. The aim of this study was to identify the mechanism and features of artifacts encountered during transesophageal echocardiography of the aorta.. Background. Artifacts are an important potential limitation of transesophageal echocardiography of the aorta.. Methods. The mechanism of the artifacts was examined by in vitro modeling. The frequency and clinical correlates of artifacts were examined by retrospective review of transesophageal echocardiograms in 36 patients with aortic pathologic lesions.. Results. Two classes of artifact were seen: linear artifacts in the ascending aorta, which may mimic intimal flaps, and mirror image artifacts in the transverse and descending thoracic aorta. Linear artifacts in the ascending aorta, seen in 44% of patients, were shown in vitro to be multiple path artifacts caused by reflection of ultrasound within the left atrium. Linear artifacts in the ascending aorta were associated with dilation of the ascending aorta and were more frequent when the ...
a) Grade 1: Intimal flaps at the level of the proximal descending aorta and 10 cm distal to the subclavian artery (arrowheads) with accompanying mediastinal hematoma. (b) Grade 3: large pseudoaneurysm formation. (c) and (d) Traumatic aortic transection (grade 4) with massive para-aortic hematoma ...
Computational fluid dynamics (CFD) provides a noninvasive method to functionally assess aortic hemodynamics. The thoracic aorta has an anatomically complex inlet comprising of the aortic valve and root, which is highly prone to different morphologies and pathologies. We investigated the effect of using patient-specific (PS) inflow velocity profiles compared to idealized profiles based on the patients flow waveform. A healthy 31 yo with a normally functioning tricuspid aortic valve (subject A), and a 52 yo with a bicuspid aortic valve (BAV), aortic valvular stenosis, and dilated ascending aorta (subject B) were studied. Subjects underwent MR angiography to image and reconstruct three-dimensional (3D) geometric models of the thoracic aorta. Flow-magnetic resonance imaging (MRI) was acquired above the aortic valve and used to extract the patient-specific velocity profiles. Subject Bs eccentric asymmetrical inflow profile led to highly complex velocity patterns, which were not replicated by the ...
Stonustoxin (SNTX) is a 148kDa, dimeric, multifunctional protein isolated from stonefish Synanceja horrida. SNTX (10-640ng/ml) progressively causes vasorelaxation to endothelium-intact, PE-precontracted rat thoracic aortic rings. The vasorelaxation was inhibited by L-NAME, PAG and BCA. Use of L-NAME with PAG or BCA showed that H2S works synergistically with NO to bring about SNTX-induced vasorelaxation. This is the first report on the involvement of H2S working together with NO to mediate a toxina??s biological effect. Interestingly, an unexpected transient increase in tone of resting rat thoracic aortic rings was observed with L-cysteine. SNTX possesses a novel B30.2 domain in each subunit. Expression and purification of Glutathione-S-transferase-B30.2 fusion proteins from E. coli BL21 resulted in co-expression of chaperonin GroEL and aggregation of fusion proteins into inclusion bodies. The proteins were not active in vasorelaxation and further studies need to be conducted ...
TY - JOUR. T1 - Reconstruction of the descending thoracic aorta by multiview compounding of 3-d transesophageal echocardiographic aortic data sets for improved examination and quantification of atheroma burden. AU - Carminati, Maria Chiara. AU - Piazzese, Concetta. AU - Weinert, Lynn. AU - Tsang, Wendy. AU - Tamborini, Gloria. AU - Pepi, Mauro. AU - Lang, Roberto Miguel. AU - Caiani, Enrico Gianluca. PY - 2015/5/1. Y1 - 2015/5/1. N2 - A robust and efficient approach to reconstruction of the descending thoracic aorta from contiguous 3-D transesophageal echocardiographic (TEE) images is proposed. An ad hoc image acquisition protocol was designed to acquire ordered and partially overlapped 3-D TEE data sets, followed by dedicated image processing to align and fuse all acquired data sets. Alignment strategy implemented pairwise rigid registration guided by a priori knowledge, and it was validated using artificially misaligned images. Image fusion was finally performed to enable visualization and ...
Significance:. Complex surgery of the ascending thoracic aorta and the aortic arch requires use of cardiopulmonary bypass (CPB) with moderate or profound total body hypothermia and circulatory arrest. As expected, coagulation disorder can be common and severe requiring multiple transfusions of blood product, which, in turn, is associated with increased risk of morbidity and mortality. Over the years, many techniques have been employed to ameliorate CPB- related bleeding with some agents such as aprotinin proving to be efficacious but centered in controversy either because of high cost or due to safety concerns.. Aprotinin is a serine protease inhibitor, intended to limit blood loss in patients undergoing surgery, was approved for use 13 years ago, and now administered in more than 250,000 surgery patients per year. Although its mechanism of action is not entirely known, it is shown to interfere with contact activation, preserve platelet function, inhibit fibrinolysis, and having some ...
Neonates with a congenital heart defect are often in need of early cardiac surgery. In complex congenital heart defects, cardiopulmonary bypass is usually employed, with or without deep hypothermic circulatory arrest (DHCA). The brain is especially vulnerable to ischemic injury, which puts neonates undergoing complex operations at high risk of neurodevelopmental disorders. Selective antegrade cerebral perfusion (ACP) instead of DHCA during these complex operations may contribute to less cerebral damage, but literature is not conclusive on this issue.. Therefore, the investigators will perform a randomised controlled trial comparing DHCA and ACP in neonatal aortic arch reconstructions, focusing on cerebral damage and neurological outcome. ...
TY - JOUR. T1 - Hybrid arch repair including supra-aortic debranching on the descending aorta. AU - Shimizu, Hideyuki. AU - Hachiya, Takashi. AU - Yamabe, Kentaro. AU - Yozu, Ryohei. PY - 2011/12. Y1 - 2011/12. N2 - A 49-year-old patient with an anastomotic pseudoaneurysm in the aortic arch was considered at high risk for conventional surgery through a median sternotomy because he had previously undergone several operations to treat aortic dissection and had a deep sternal infection after one procedure. Therefore, a hybrid repair was performed. Stent grafts were placed bridging two previously implanted aortic prostheses, which were in the ascending aorta and descending aorta, respectively. The supra-arch vessels were perfused by means of an extra-anatomic bypass from the descending aorta. The aneurysm was completely excluded from the blood flow, and the patient had no serious complications.. AB - A 49-year-old patient with an anastomotic pseudoaneurysm in the aortic arch was considered at high ...
Aberrant right subclavian artery (ARSA) or arteria lusoria is one of the most common congenital aortic arch anomaly with prevalence ranging from 1-2%. However, it is mostly asymptomatic and consequently often found sporadically during various diagnostic procedures with prevalence of 0.45% during coronary angiography.
Background: Recent guidelines have suggested that presence of coronary artery calcium (CAC) is an independent marker of adverse cardiovascular disease (CVD) events and mortality. However the predictive value of thoracic aorta calcification (TAC) that can be additionally identified without further scanning during assessment of CAC is unknown.. Method: We followed a cohort of 8418 asymptomatic individuals (mean age: 53 ± 10 years, 69% men) undergoing cardiac risk factor evaluation and coronary calcium testing with electron-beam CT for median period of 5.0 years. Multivariable Cox proportional hazards models were developed to predict all-cause mortality obtained from the National Death Index with presence of TAC.. Results: 141 (2%) all cause deaths were recorded. Overall survival was 96.7% and 98.8% for subjects with and without detectable TAC (p , 0.0001). As compared to those with absent TAC (reference group) the hazard ratio for mortality for subjects with TAC was 3.07 (95% CI: 2.20 - 4.38) in ...
Thromboxane is a vasoactive omega-6-derived lipid implicated in hypertension. Omega-3 fatty acid derivatives including resolvin (Rv) E1 have important roles in the resolution of inflammation, but their ability to mediate vasomotor activity is unknown. We assessed whether RvE1 modulates contraction of rat thoracic aorta and human pulmonary artery (HPA) in vitro.. Rats were culled by CO2 inhalation and cervical dislocation, and the thoracic aorta was removed. HPA were obtained with informed consent from lung tissue of surgical patients at Southampton General Hospital. Segments of aorta or HPA were incubated in DMEM-F12 with or without RvE1 (10 nM, 100 nM or 300 nM) for 1 or 24 hours, and then mounted on a wire myograph. Mounted segments were bathed at 37[[Unable to Display Character: ]]C in Krebs buffer, gassed (95%/5% O2/CO2) and set to 1.5 g of baseline tension. Functional integrity was confirmed by a contractile response to 125 mM KPSS. After washing to restore baseline tension, a ...
Meziane, M.A.; Fishman, E.K.; Siegelman, S.S., 1984: CT diagnosis of hemopericardium in acute dissecting aneurysm of the thoracic aorta
Anastomotic pseudoaneurysm is a rare complication following aorta replacement. However, this condition is life-threatening because of the high risk of rupture. This complication has a mortality rate of 61% if no intervention is performed.[1] Its foremost cause may be the high local tension or the edematous aortic wall, which causes sutures to lacerate the aortic wall. Another possible cause is the graft infection.[2]. The incidence rate of anastomotic pseudoaneurysm ranges from 0.5% to 15%.[3] To date, two interventions are mainly used to manage this condition: The surgical repair and thoracic endovascular aortic repair. Surgical treatment involves the replacement of a prosthetic graft or direct repair via a redo left lateral thoracotomy. Such redo thoracotomy is extremely difficult because of the adhesion of lungs to the chest wall in the left chest cavity. The high risk of lung injury was reported for more than 30% of the patients.[4] Meanwhile, open surgery has a high mortality ...
OBJECTIVE This study was undertaken to define matrix metalloproteinase (MMP) expression in the anterior and posterior wall of descending thoracic aortic aneurysms (TAAs) and correlate it with specific computed tomography (CT) image sites within the descending thoracic aorta. METHODS Serial CT images of patients with TAAs were compared with age- and gender-matched normal descending thoracic aortas at levels T4-T12. The mean circumference of the TAAs was 153 mm (n = 12) and 148 mm (n = 11) at T8 and T10, respectively, compared with 75 mm (n = 12) and 75 mm (n = 10) in controls (P | .001). Aortic tissue was collected from a separate set of eight patients undergoing descending TAA resection (processed | or =12 hours of excision) and six cadavers (processed | or =24 hours of death). Tissue collected between the intercostals arteries was defined as posterior wall, and directly opposite was the anterior wall. MMP-9 and MMP-2 messenger RNA (mRNA) extracted from aortic tissue was analyzed by quantitative real
TY - JOUR. T1 - Impact of treatment modality on vascular function in coarctation of the aorta. T2 - The LOVE-COARCT study. AU - LOVE-COARCT Study. AU - Martins, José D.. AU - Zachariah, Justin. AU - Tierney, Elif Seda Selamet. AU - Truong, Uyen. AU - Morris, Shaine A.. AU - Kutty, Shelby. AU - de Ferranti, Sarah D.. AU - Guarino, Maria. AU - Thomas, Boban. AU - Oliveira, Diana. AU - Marinho, António. AU - António, Marta. AU - Gauvreau, Kimberlee. AU - Jalles, Nuno. AU - Geva, Tal. AU - Carmo, Miguel M.. AU - Prakash, Ashwin. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Background-Optimally treated patients with coarctation of the aorta remain at risk for late vascular dysfunction. The effect of treatment modality on vascular function is unknown. The LOVE-COARCT (Long-term Outcomes and Vascular Evaluation After Successful Coarctation of the Aorta Treatment) study was done to compare vascular function in patients with coarctation of the aorta treated with surgery, balloon dilation (BD), or stent ...
Arterial hypertension remains a common problem after coarctation repair, and is a major concern in the long-term outcome of these patients. The pathophysiology of hypertension after successful surgical treatment of aortic coarctation, and in the absence of re-coarctation is still poorly understood. It has been suggested that coarctation of the aorta could represent a primary or secondary systemic vasculopathy rather than an isolated local disease of the aortic isthmus. These changes are thought to be involved in the development of hypertension in the absence of re-coarctation as well as premature cardiovascular events.. A number of observational studies in patients after coarctation repair have proposed endothelial dysfunction as measured by FMD, or a decreased reactivity to nitric oxide of the arterial wall as a key player in this respect.3 ,19-22 Impairment of FMD in these patients has been described with20 and without evidence of increased blood pressures.3 This has lead to the hypothesis ...
The long-term outlook for children who have had their coarctation repaired, either with surgery or angioplasty, is excellent. Children who have successful repair of coarctation usually can live full and productive lives. Women usually can become pregnant safely. However, medical problems can occur after repair.. Recoarctation. Recoarctation is the redevelopment of a narrowing in the aorta. This problem occurs more commonly in children who have had their coarctation repaired during the first year of life. Recoarctation occurs in approximately 10% to 20% of children who have had their repair in infancy, and in less than 3% of children who have had their repair after 3 years of age. Treatment of recoarctation of the aorta usually is with a balloon angioplasty.. High blood pressure. High blood pressure is one of the most common medical problems seen in patients after successful repair of coarctation. Approximately 60% of people who have had their coarctation repaired will require medication to treat ...
The aorta is a large artery with a thick wall. This is necessary for it to handle a large volume of blood exiting the heart and contend with high pressure. However, there are several reasons why the inner lining of the wall can be compromised. This can cause the inner lining to tear. The blood under high pressure may then enter the wall of the aorta and create a channel for the blood between the inner and middle layer.. It is more likely to occur if the blood pressure rises to levels that are too high. Another factor is that wall of the aorta may be weakened. However, in most cases the blood may not extend beyond the middle layer of the aortic wall. Fortunately this middle layer is significantly strong to withstand the high pressure for a period of time. Eventually the blood can penetrate through the middle layer and lead to a rupture of the aorta.. Blood may then pour out of the aorta from where it bursts. As a result the blood pressure cannot be maintained at normal levels and oxygen-rich ...
Traumatic transection of the thoracic aorta is a life-threatening complication that most commonly occurs after high-speed motor vehicle collisions. Although such injuries were previously treated with open surgical reconstruction, they are now more co
Goldstein, Lee J., "Stroke in thoracic aortic surgery : incidence, impact, etiology, and prevention" (2000). Yale Medicine Thesis Digital Library. 2655 ...
TY - JOUR. T1 - Coarctation of the aorta. T2 - Lifelong surveillance is mandatory following surgical repair. AU - Brown, Morgan L.. AU - Burkhart, Harold M.. AU - Connolly, Heidi M.. AU - Dearani, Joseph A.. AU - Cetta, Frank. AU - Li, Zhuo. AU - Oliver, William C.. AU - Warnes, Carole A.. AU - Schaff, Hartzell V. PY - 2013/9/10. Y1 - 2013/9/10. N2 - Objectives The objective of our study was to review the long-term outcomes of patients undergoing surgical repair of aortic coarctation. Background Surgical repair of aortic coarctation has been performed at the Mayo Clinic, Rochester, Minnesota, for over 60 years. Methods Between 1946 and 2005, 819 patients with isolated coarctation of the aorta underwent primary operative repair. Medical records were reviewed and questionnaires mailed to the patients. Results Mean age at repair was 17.2 ± 13.6 years. The majority (83%) had pre-operative hypertension. Operations included simple and extended end-to-end anastomosis (n = 632), patch angioplasty (n = ...
Causes of Coarctation of aorta dominant including triggers, hidden medical causes of Coarctation of aorta dominant, risk factors, and what causes Coarctation of aorta dominant.
If you have tried to treat this ailment, please complete the following form to help us better our data, and help guide people to the best possible treatments. CureCrowd is a public resource with absolutely no vested interest in the outcomes of our studies. ...
Tissue and Eye banks across Australia provide data for cardiovascular, musculoskeletal, skin tissue and amnion donations.. Musculoskeletal donations can be in the form of bone, tendon and ligaments and are utilised for knee and hip replacements, reconstructive orthopaedic surgery following trauma or disease and spinal deformities and can aid in prevention of limb loss following tumour removal. Just one musculoskeletal donation can aid many recipients and greatly improve their quality of life.. Cardiovascular tissue incorporates donations of heart valves, pericardium and thoracic aorta. Heart valves are necessary to regulate the flow of blood to and from the heart, whereas pericardium can be used during neurosurgery or, like the thoracic aorta, can also be used for vascular repair of defects or injury.. Donated skin contributes to saving lives and improving long term outcomes for patients who suffer severe burns. Donated skin is essential when a patients own skin cannot be used for grafting. ...
Individuals from across the country travel to the Bluhm Cardiovascular Institute to receive exceptional patient care and the most advanced treatments available. Meet a few of our patients that have successfully undergone treatment at the Bluhm Cardiovascular Institute.
The long-term outlook for children who have had their coarctation repaired, either with surgery or angioplasty, is excellent. Children who have successful repair of coarctation usually can live full and productive lives. Women usually can become pregnant safely. However, medical problems can occur after repair.. Recoarctation. Recoarctation is the redevelopment of a narrowing in the aorta. This problem occurs more commonly in children who have had their coarctation repaired during the first year of life. Recoarctation occurs in approximately 10% to 20% of children who have had their repair in infancy, and in less than 3% of children who have had their repair after 3 years of age. Treatment of recoarctation of the aorta usually is with a balloon angioplasty.. High blood pressure. High blood pressure is one of the most common medical problems seen in patients after successful repair of coarctation. Approximately 60% of people who have had their coarctation repaired will require medication to treat ...
Find best Doctors for Aortic Coarctation in Hsr Layout Bengaluru. Get medication advice from our expert doctors & book appointment for Aortic Coarctation online at Ask Apollo.
Enlargement of the ascending aorta indicates a weakening of the aortic wall, according to Cedars-Sinai. Often, an enlarged ascending aorta is diagnosed as an aneurysm....
The adherent culture of rat thoracic aorta cells featured in this section was stained with Alexa Fluor 488 conjugated to the lectin concanavalin A, which selectively binds to alpha-mannopyranosyl and alpha-glucopyranosyl residues (primarily in the endoplasmic reticulum).
During an abdominal aorta scan, the mobile technologist uses two types of ultrasound to systematically interrogate the entire length of the abdominal aorta. He
When someone has coarctation of the aorta, that persons aorta (the major blood vessel that carries blood away from the heart to the body) is narrowed at some point.
Coarctation of the aorta (COA) is a narrowing of the aorta, the major blood vessel that carries blood away from the heart to the body.
When someone has coarctation of the aorta, that persons aorta (the major blood vessel that carries blood away from the heart to the body) is narrowed at some point.
Abstract: An unusual vascular ring anomaly consisting of a persistent right aortic arch and a left ligamentum arteriosum extending from the main pulmonary artery to an aberrant left subclavian artery and left aortic arch remnant complex was identified in a German shepherd dog and a great Dane. The left subclavian artery and left aortic arch remnant complex originated at the junction between the right distal aortic arch and the descending aorta and coursed dorsal to the oesophagus in a cranial direction. The attachment of the ligamentum arteriosum to the aberrant left subclavian artery was approximately 5 cm cranial to the point of origin of the aberrant left subclavian artery and left aortic arch remnant complex from the descending aorta in both dogs. This anomaly observed in both dogs is similar to an anomaly reported in humans, in which a persistent right aortic arch is found in conjunction with an aberrant left subclavian artery and a left aortic arch remnant (Kommerells diverticulum). ...
TY - JOUR. T1 - Transesophageal echocardiography in the diagnosis of diseases of the thoracic aorta. T2 - Part 1. Aortic dissection, aortic intramural hematoma, and penetrating atherosclerotic ulcer of the aorta. AU - Willens, Howard J.. AU - Kessler, Kenneth M.. PY - 1999/1/1. Y1 - 1999/1/1. KW - Acute aortic syndrome. KW - Aortic dissection. KW - Aortic intramural hematoma. KW - Penetrating aortic ulcer. KW - Thoracic aorta. KW - Transesophageal echocardiography. UR - http://www.scopus.com/inward/record.url?scp=0033388643&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0033388643&partnerID=8YFLogxK. U2 - 10.1378/chest.116.6.1772. DO - 10.1378/chest.116.6.1772. M3 - Article. C2 - 10593804. AN - SCOPUS:0033388643. VL - 116. SP - 1772. EP - 1779. JO - Chest. JF - Chest. SN - 0012-3692. IS - 6. ER - ...
Citation: Kumari, R. et al. (2003) ATP and UTP responses of cultured rat aortic smooth muscle cells revisited: Dominance of P2Y2 receptors. British Journal of Pharmacology, 140 (7), pp. 1169-1176. ...
The authors concluded that endovascular technology could be helpful in treating selected young patients with genetically triggered thoracic aortic disease. However, we should be caution evaluating results of this mid-term follow-up study. Most aortic surgeons support the idea of endovascular therapy of genetically triggered aortic disease, but only in case of already prosthetic replaced aortic segments corresponding to proximal and distal landing zones. Endovascular treatment of the native aorta in Marfan and Loeys-Dietz syndrome patients is not recommended due to high-risk of later endoleaks type I. Further research and long-term follow-up studies are necessary to identify patients with genetically triggered thoracic aortic disease who benefit from endovascular aortic repair and delineate contraindication for endovascular approach.. ...
Over recent years, an improved consensus has been established regarding diagnosis and management of type B aortic dissection (TBAD). Primary conservative medical treatment with antihypertensive agents in combination with close surveillance seems to be justified in TBAD, until complications such as aneurysmal expansion, rupture, or progression of the initial dissection ... read more occur. Several clinical and radiological predictors of aortic growth in uncomplicated TBAD patients have been identified and can be used to select patients at high-risk for aortic enlargement and rupture during follow-up. Those patients might benefit from closer surveillance or early endovascular intervention. Over recent decades, the management of thoracic aortic pathologies has evolved to include endovascular approaches next to conventional open aortic repair. Currently, thoracic endovascular aortic repair (TEVAR) is the preferred approach for patients presenting with complicated TBAD and other thoracic aortic ...
INTRODUCTION: Floating thrombus in an aberrant right subclavian artery is a rare cause of peripheral arterial embolic events. CASE REPORT: We report a 45-year-old woman who presented with an ischemia of the right superior limb from embolic event. The diagnosis of mobile thrombus in an aberrant right subclavian artery was obtained with transoesophageal echocardiography and computed tomography. After three weeks of oral anticoagulant therapy, there was no significant resolution of the thrombus, and a surgical treatment was performed to prevent further embolization. The surgical procedure consisted of thrombectomy and reimplantation of the aberrant right subclavian artery to the right carotid artery. Postoperative recovery was uneventful. CONCLUSION: This case report illustrates that transoesophageal echography and computed tomography are useful to detect mobile thrombus of the thoracic aorta and is warranted in any embolic event in young patients.
TY - JOUR. T1 - Modulation of collagen synthesis by tumor necrosis factor alpha in cultured vascular smooth muscle cells. AU - Hiraga, Syouichi. AU - Kaji, Toshiyuki. AU - Ueda, Yoshimichi. AU - Zisaki, Fumiko. AU - Iwata, Kazushi. AU - Koizumi, Fumitomo. AU - Okada, Yasunori. AU - Katsuda, Shogo. AU - Nakanishi, Isao. PY - 1999/12/10. Y1 - 1999/12/10. N2 - Collagen synthesis in vascular smooth muscle cells (SMCs) after exposure to tumor necrosis factor alpha (TNF-α) was investigated using a culture system. The synthesis of collagenase-digestible proteins (CDP) and noncollagenous proteins (NCP) was evaluated by the [3H]proline incorporation. It was shown that TNF-α markedly suppresses the incorporation of [3H]proline into both CDP and NCP in confluent cultures of SMCs but not in sparse cultures of the cells. Such a marked suppression by TNF-α was not observed in confluent bovine aortic endothelial cells and human fibroblastic IMR-90 cells. In confluent SMCs, the synthesis of CDP was more ...
বক্ষপিঞ্জর (Thoracic cage). *উরঃফলক (Sternum). *পিঞ্জরাস্থি (Rib). *প্রগণ্ডাস্থি (Humerus). *কনুই (Elbow). *বহিঃপ্রকোষ্ঠাস্থি ( ... মহাধমনী (Aorta). *অলিন্দ (Atrium). *নিলয় (Ventricle). *হৃৎকপাটিকা (Heart valve). *রক্ত (Blood) ...
"The Annals of Thoracic Surgery. 85 (3): 1132-1134. doi:10.1016/j.athoracsur.2007.11.031. ISSN 0003-4975. PMID 18291225.. ... Within the work On the Nature of Man, suggest that the bladder stones first form within or attached to the aorta, much like any ... The most common ones are fever, thoracic pain, sweating, heaviness in the chest, and a cough.[44] Treating an empyema was ... Papavramidou, Niki; Christopoulou-Aletra, Helen (2008-03-01). ""Empyemas" of the Thoracic Cavity in the Hippocratic Corpus". ...
Malformed aorta, slow pulse, ischemia: these cause reduced blood flow to the renal arteries, with physiological responses as ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Aortic rupture ...
... and from the spinous processes of the upper three or four thoracic vertebrae. ... Muscular branches of the aorta. Nerve. Posterior ramus of spinal nerves C3 and C4. ...
... aorta, major vessels, esophagus, thoracic duct, and diaphragm. Gunshots to the chest can thus cause severe bleeding (hemothorax ... Mirvis, Stuart E. (April 2004). "Diagnostic imaging of acute thoracic injury". Seminars in Ultrasound, CT, and MR. 25 (2): 156- ... Meredith, J. Wayne; Hoth, J. Jason (February 2007). "Thoracic trauma: when and how to intervene". The Surgical Clinics of North ... descending aorta, and other abdominal vessels and nerves. Gunshots to the abdomen can thus cause severe bleeding, release of ...
Renal artery stenosis - is the narrowing of renal arteries that carry blood to the kidneys from the aorta.[2] ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Aortic rupture ...
It passes beneath the aortic arch, crosses in front of the esophagus, the thoracic duct, and the descending aorta, and has the ... The carina of the trachea is located at the level of the sternal angle and the fifth thoracic vertebra (at rest). ... It enters the root of the left lung opposite the sixth thoracic vertebra. ... It enters the root of the right lung at approximately the fifth thoracic vertebra. The right main bronchus subdivides into ...
The formation of the elastic fibers in the heart valves and the aorta require the involvement of both FBN-1 and FBN-2.[10] It ... curved spines usually resulting in thoracic scoliosis, hyperflexible joints, pectus excavatum, retinal detachment and sunken ... Fibrillin-1 and fibrillin-2 are also crucial for the development of elastic fibers in the aorta. While expression of fibrillin- ... The weakened elastic fibers will result in an impaired durability and distensibility in the heart valves and aorta. This ...
... leading to changes in the phospholipid fatty acid composition in the aorta, the main artery of the heart, thereby raising risk ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Aortic rupture ...
... or for access to the thoracic aorta or the anterior spine (the latter may be necessary to access tumors in the spine). The ... Thoracic epidural analgesia or paravertebral blockade have shown to be the most effective methods for post-thoracotomy pain ... Treatment to aid pain relief for this condition includes intra-thoracic nerve blocks/opiates and epidurals, although results ... the first step used to facilitate thoracic surgeries including lobectomy or pneumonectomy for lung cancer or to gain thoracic ...
Thoracic aorta injury. *Cardiac tamponade. *GI *Blunt kidney trauma. *Ruptured spleen. *Neuro *Penetrating head injury ...
lateral thoracic artery. *subscapular artery. Страница 1335[редактиране , редактиране на кода]. *Артерии *scapular circumflex ... ascending aorta. *aortic arch. *innominate artery. *left common carotid artery. *internal mammary artery ...
History of Lung Transplantation, Turkish Thoracic Journal, Gül Dabak and Ömer Şenbaklavacı, 17(2): pages 71-75, April 2016. ... 1955: First heart valve allograft into descending aorta (Canada). *1963: First successful lung transplant by James D. Hardy ... "OPTN Policy 3.7 - Allocation of Thoracic Organs". United Network for Organ Sharing. 31 January 2013. Archived from the original ... Interactive Cardiovascular and Thoracic Surgery. 10 (6): 1026-1033. doi:10.1510/icvts.2009.229757. PMID 20308266.. CS1 maint: ...
left ventricle to aorta Rastelli procedure. right ventricle to pulmonary artery Sano shunt. compound procedures. for ... cutting the skull for brain surgery or cutting the sternum for thoracic (chest) surgery to open up the rib cage. Whilst in ... first performed a successful ligation of the abdominal aorta, and James Syme (1799-1870) pioneered the Symes Amputation for the ...
The lower esophagus lies behind the heart and curves in front of the thoracic aorta. From the bifurcation of the trachea ... the parts of the esophagus in the thorax from the bronchial arteries and branches directly from the thoracic aorta, and the ... The thoracic duct, which drains the majority of the body's lymph, passes behind the esophagus, curving from lying behind the ... The esophagus is innervated by the vagus nerve and the cervical and thoracic sympathetic trunk.[5] The vagus nerve has a ...
彈性動脈為管徑最大的動脈,通常離開心臟不遠,如主動脈、胸主動脈(thoracic aorta)、腹主動脈(abdominal aorta)、鎖骨
Dissection of the descending thoracic aorta extending into the ascending aorta. A therapeutic challenge. J. Thorac. Cardiovasc ... The Journal of Thoracic and Cardiovascular Surgery. 138: 674-7 *^ 19.0 19.1 19.2 Woo KM, Schneider JI. High-risk chief ... 在受損主動脈段插入一個覆膜支架,如:在胸主動脈腔內修復(thoracic endovascular aortic repair,TEVAR)使用。它通常是和正在進行的藥物治療一起使用。 ... Surgical management of dissecting aneurysms of the aorta. J
It contains the aorta and the thoracic duct. two lesser apertures of right crus. greater and lesser right splanchnic nerves and ... maximizing the efficacy of lowered thoracic pressure returning blood to the heart. The aorta does not pierce the diaphragm but ... which arise directly from the thoracic aorta; and from the lower internal intercostal arteries. From below, the inferior ... The thoracic diaphragm, or simply the diaphragm (Ancient Greek: διάφραγμα, romanized: diáphragma, lit. 'partition'), is a sheet ...
"Journal of Thoracic Imaging. 24 (4): 285-298. doi:10.1097/RTI.0b013e3181c1ab83. PMID 19935225. Retrieved 24 May 2019.. ... and a groove below it for the descending aorta. The left subclavian artery, a branch off the aortic arch, sits in a groove from ... The anterior thoracic wall, the airways and the pulmonary vessels anterior to the root of the lung have been digitally removed ... They are situated within the thoracic cavity of the chest. The right lung is bigger than the left, which shares space in the ...
... and advancing an intravascular catheter through the aorta towards the vertebral arteries. At that point, radiocontrast is ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Coronary artery aneurysm ...
After the examination, the body has an open and empty thoracic cavity with chest flaps open on both sides, the top of the skull ... The heart can then be removed by cutting the inferior vena cava, the pulmonary veins, the aorta and pulmonary artery, and the ... Pathologist performing a human dissection of the abdominal and thoracic organs in an autopsy room. ...
The superficial part of the cardiac plexus lies beneath the arch of the aorta, in front of the right pulmonary artery. It is ... The right sympathetic chain and its connections with the thoracic, abdominal, and pelvic plexuses. (Cardiac plexus labeled at ... This ganglion, when present, is situated immediately beneath the arch of the aorta, on the right side of the ligamentum ...
The ventral aorta delivers blood to the gills where it is oxygenated and flows, through the dorsal aorta, into the rest of the ... and the European Association for Cardio-Thoracic Surgery (EACTS)". European Journal of Cardio-Thoracic Surgery. 42 (4): S1-44. ... In tetrapods, the ventral aorta has divided in two; one half forms the ascending aorta, while the other forms the pulmonary ... Aorta,[a] pulmonary trunk and right and left pulmonary arteries,[b] right coronary artery, left main coronary artery[c]. ...
Esophageal branches of thoracic part of aorta. *Mediastinal. parietal: *Posterior intercostal 3·11 ... Възходяща аорта (aorta ascendens)[редактиране , редактиране на кода]. Дясна коронарна артерия (a. coronaria dextra)[редактиране ... Коремна аорта (aorta abdominalis)[редактиране , редактиране на кода]. Чревен ствол (truncus coeliacus)[редактиране , ... 4 Коремна аорта (aorta abdominalis) *4.1 Чревен ствол (truncus coeliacus). *4.2 Горна опорачна артерия (a. mesenterica superior ...
The thoracic aorta, viewed from the left side. (Pericardiacophrenic labeled at center left.) ... The pericardiacophrenic artery is a long slender branch of the internal thoracic artery. It accompanies the phrenic nerve, ... On their course through the thoracic cavity, the pericardiacophrenic arteries are located within and supply the fibrous ...
... the thoracic aorta has a maximum diameter of 40 mm at the root. By the time it becomes the ascending aorta, the diameter should ... The aortic arch, arch of the aorta, or transverse aortic arch (English: /eɪˈɔːrtɪk/[1][2]) is the part of the aorta between the ... Wikimedia Commons has media related to Arcus aortae.. *Right Aortic Arch[permanent dead link] Anatomy Teaching Case from MedPix ... The aorta begins at the level of the upper border of the second sternocostal articulation of the right side, and runs at first ...
The spine has cervical, thoracic, lumbar and caudal regions with the number of cervical (neck) vertebrae highly variable and ... unlike in the mammals where the left aortic arch forms this part of the aorta. The postcava receives blood from the limbs via ... especially flexible, but movement is reduced in the anterior thoracic vertebrae and absent in the later vertebrae. The last few ...
Left heart → Aorta → Arteries → Arterioles → Capillaries → Venules → Veins → Vena cava → (Right heart) ... An efferent lymph vessel may directly drain into one of the (right or thoracic) lymph ducts, or may empty into another lymph ... and the thoracic duct (for the rest of the body); both ducts drain into the circulatory system at the right and left subclavian ... the thoracic duct. These vessels drain into the right and left subclavian veins respectively. ...
thoracic aortic aneurysm A thoracic aortic aneurysm is an abnormal bulging or ballooning of the portion of the aorta the passes ...
... the need for an Nrf2-activator delivery system Constitutive modeling of ascending thoracic aortic aneurysms using ... imaging in rodents and primates Nanonet force microscopy for measuring forces in single smooth muscle cells of the human aorta ... identifies genetic alterations that might be targeted with existing drugs or used as biomarkers The Society of Thoracic ...
Correlations between transmural mechanical and morphological properties in porcine thoracic descending aorta. Hemmasizadeh, A ... collagen fibers on dissection properties of human ascending thoracic aorta.. Pal S; Tsamis, A; PASTA, Salvatore ; DAMORE, ... A Custom Image-Based Analysis Tool for Quantifying Elastin and Collagen Micro-Architecture in the Wall of the Human Aorta from ... Constitutive modeling of ascending thoracic aortic aneurysms using microstructural parameters. PASTA, Salvatore ; Phillippi, J ...
Thoracic aorta angiogram * Abdominal aorta angiogram * Renal angiogram * Aorto-bifemoral angiogram * Coronary angiogram ...
Note: The goal of the SegTHOR challenge is to automatically segment 4 OAR: heart, aorta, trachea, esophagus. Participants will ... Segmentation of THoracic Organs at Risk in CT images (SegTHOR). https://competitions.codalab.org/competitions/21012 ...
The devices implant location is one-the descending thoracic aorta is outside of the heart and downstream from the carotid ... When the cardiologist has moved Aortix into the descending thoracic aorta, the catheter sheath is retracted to anchor Aortix to ... the device in a quick procedure by snaking a catheter into the patients femoral artery and into the descending thoracic aorta ...
The thoracic aortas were used for hematoxylin-eosin staining. Results: In both hepatic injury and nonhepatic injury groups, TC ...
Thoracic Aorta Medicine & Life Sciences * Pulmonary Artery Medicine & Life Sciences View full fingerprint ...
It could very well be an abdominal aortic aneurysm, which means their descending aorta may burst open at any minute. Find out ... the underoos are coming off so I can check the genitalia and rectum for bleeding if there is any thoracic /abdominal trauma or ... pain in any area that indicates thoracic /abdominal injury.. Head, eyes, ears, nose, and throat (HEENT). Start at the head and ...
J. C. L. Mamo and J. R. Wheeler, "Chylomicrons or their remnants penetrate rabbit thoracic aorta as efficiently as do smaller ... They pass through the thoracic duct and into the blood where they undergo rapid lipolysis, losing some of their TG to form ... "The influence of chylomicron remnants on endothelial cell function in the isolated perfused rat aorta," Atherosclerosis, vol. ...
The sensitivity of thoracic aorta preparations to histamine decreased with age.. ketoconazole 2 shampoo 120ml price ... Thoracic CT and/or angioscan provided the diagnosis in five patients. Among many of virulence factors, the production of ...
ROUTINARY USE OF FIBRIN SEALANTS TO PREVENT PROLONGED AIR LEAK IN THORACIC SURGERT: OUR EXPERIENCE. Cocorullo, G., Tomasello, G ...
Aorta Clamps, Rib Spreaders Rib Contractors Lung Spatulas *Instruments For Cranail Opening Cervical Traction Tongs ... Gum Scissors, Thoracic Scissors Vascular Surgery Scissors *Iris Scissors Fine Operating Scissors ...
Abdominal aorta. Definition. •Continuation of thoracic aorta after passing through the aortic hiatus of diaphragm. •Three ... It passes left of the aorta to reach inferior border of the body of the pancreas. This part joins with the jejunum. •Ligament ... Horizontal part is about 3 inches long and crosses anterior to the inferior vena cava and abdominal aorta and posterior to the ... Abdominal part is left gastric artery (from celiac trunk) and left inferior phrenic artery (from abdominal aorta). •Venous ...
... ameliorated high-glucose induced proliferation and migration of vascular smooth muscle cells from rat thoracic aortas via ...
Locating the aorta and vena cava The transverse colon (Ct) is a bar to scanning, along with the antrum (An) and duodenum (Du) ... tion and experience in trauma cases contributed significantly to the growth of thoracic surgery and led to improved mor- tality ... The atretic aorta is reconstructed using the pipeline pulmonary artery augmented with synthetic patch lay [url=https://mopdog. ...
European Journal of Cardio-Thoracic Surgery (Followers: 9) European Journal of Cardio-Thoracic Surgery Supplements (Followers: ... AORTA Archives of Cardiovascular Diseases (Followers: 5) Archives of Cardiovascular Diseases Supplements (Followers: 3) ...
Aorta X-Ray (Aortography). $9,800 - $21,300 Free Quote X-Ray of Artery - Head and Neck (Angiography). $6,600 - $14,200 Free ... Thoracic CT Scan - Thorax. $1,700 - $3,800 Free Quote Chest CT Scan. $1,850 - $4,000 Free Quote ...
The aorta is the find yourself always tring to "fix" things this outlay silagra amass a the body. Its already sale buy silagra ... The larger the thoracic are a few adverse most advanced minimally invasive people in the specific drug. People with angina are ...
aorta, thoracic - drug effects (64) 64 Filter by. Remove filter. norepinephrine - pharmacology (63) 63 ... Guinea-pig aorta , Curcumin , d-Amphetamine hydrochloride (PubChem CID: 5826) , RAT AORTA , TRACE AMINES , PHENYLEPHRINE , beta ... Full Text Non-adrenergic vasoconstriction and vasodilatation of guinea-pig aorta by β-phenylethylamine and amphetamine - Role ...
This curvature is regarded by others as being produced by the aortic arch and upper part of the descending thoracic aorta - a ... The thoracic curve, concave forward, begins at the middle of the second and ends at the middle of the twelfth thoracic vertebra ... Thoracic - 12 vertebrae (T1-T12). • Distinguished by the presence of costal facets for the articulation of the heads of ribs • ... The thoracic and pelvic curves are termed primary curves, because they alone are present during fetal life. In the early embryo ...
Spinal ischemia is a terrible complication of the thoracic aorta repair. Can we possibly prevent it?growkudos.com/publications/ ...
The SA Journal of Radiology is the official journal of the Radiological Society of South Africa and the Professional Association of Radiologists in South Africa and Namibia. The SA Journal of Radiology is a general diagnostic radiological journal which carries original research and review articles, pictorial essays, case reports, letters, editorials, radiological practice and other radiological articles.
Aortopulmonary Window is a rare defect of the heart in which there is a hole connecting the aorta and the pulmonary artery abs ... Paediatric Cardio-thoracic Vascular Surgery Please inquire Includes neonatal repairs, arrhythmia surgery, coronary artery ... An enlargement of the aorta, the main blood vessel that delivers blood to the body, at the level of the abdomen. An abdominal ... The surgery has two main approaches, i.e., diversion of the internal thoracic artery to the left anterior descending artery in ...
  • She underwent emergent replacement of her descending thoracic aorta. (soap.org)
  • A patient who underwent thoracic surgery at our facility was transferred to another acute care facility on November 30 for lung transplant evaluation (service not provided at our facility), but was not a candidate and was transferred back to us on December 6. (sts.org)
  • They pass through the thoracic duct and into the blood where they undergo rapid lipolysis, losing some of their TG to form smaller chylomicron remnants (CMRs), which then deliver the remaining TG, cholesterol, and other lipids to the liver. (hindawi.com)
  • 1. The authors have not used high thoracic epidural blockade, allowing to achieve a greater degree of increase in the volume of the vascular bed. (russianpatents.com)
  • 2019. Immediate of Impact Prosthetic Graft Replacement of the Ascending Aorta on Circumferential Strain in the Descending Aorta. . (cornell.edu)
  • Please clarify whether we should only consider the current thoracic malignancy for this data element, or whether "Current Malignancy" is an inadvertent carry-over from v2.3. (sts.org)