The main trunk of the systemic arteries.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
Pathological processes involving any part of the AORTA.
A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
An abnormal balloon- or sac-like dilatation in the wall of AORTA.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
The nonstriated involuntary muscle tissue of blood vessels.
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.
An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
Drugs used to cause constriction of the blood vessels.
Inflammation of the wall of the AORTA.
Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Drugs used to cause dilation of the blood vessels.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.
The vessels carrying blood away from the heart.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
That phase of a muscle twitch during which a muscle returns to a resting position.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
The condition of an anatomical structure's being dilated beyond normal dimensions.
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
A diet that contributes to the development and acceleration of ATHEROGENESIS.
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
The inferior and superior venae cavae.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR).
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.
Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Elements of limited time intervals, contributing to particular results or situations.
The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.
Cholesterol present in food, especially in animal products.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.
A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
Resistance and recovery from distortion of shape.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
The act of constricting.
A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Arteries which arise from the abdominal aorta and distribute to most of the intestines.
Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.
The first and largest artery branching from the aortic arch. It distributes blood to the right side of the head and neck and to the right arm.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Pathologic deposition of calcium salts in tissues.
The main artery of the thigh, a continuation of the external iliac artery.
A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
The plan and delineation of prostheses in general or a specific prosthesis.
Operative procedures for the treatment of vascular disorders.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.
A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.
Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Radiography of blood vessels after injection of a contrast medium.
A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
A fetal blood vessel connecting the pulmonary artery with the descending aorta.
A technique to arrest the flow of blood by lowering BODY TEMPERATURE to about 20 degrees Centigrade, usually achieved by infusing chilled perfusate. The technique provides a bloodless surgical field for complex surgeries.
Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.
Surgical incision into the chest wall.
A rare amino acid found in elastin, formed by condensation of four molecules of lysine into a pyridinium ring.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Cell surface proteins that bind THROMBOXANES with high affinity and trigger intracellular changes influencing the behavior of cells. Some thromboxane receptors act via the inositol phosphate and diacylglycerol second messenger systems.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
The veins and arteries of the HEART.
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.
The dilatation of the aortic wall behind each of the cusps of the aortic valve.
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
A large vessel supplying the whole length of the small intestine except the superior part of the duodenum. It also supplies the cecum and the ascending part of the colon and about half the transverse part of the colon. It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra.
The flow of BLOOD through or around an organ or region of the body.
A subclass of alpha-adrenergic receptors that mediate contraction of SMOOTH MUSCLE in a variety of tissues such as ARTERIOLES; VEINS; and the UTERUS. They are usually found on postsynaptic membranes and signal through GQ-G11 G-PROTEINS.
A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE.
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Created as a republic in 1918 by Czechs and Slovaks from territories formerly part of the Austro-Hungarian Empire. The country split into the Czech Republic and Slovakia 1 January 1993.

A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. (1/4396)

Microdeletions of chromosome 22q11 are the most common genetic defects associated with cardiac and craniofacial anomalies in humans. A screen for mouse genes dependent on dHAND, a transcription factor implicated in neural crest development, identified Ufd1, which maps to human 22q11 and encodes a protein involved in degradation of ubiquitinated proteins. Mouse Ufd1 was specifically expressed in most tissues affected in patients with 22q11 deletion syndrome. The human UFD1L gene was deleted in all 182 patients studied with 22q11 deletion, and a smaller deletion of approximately 20 kilobases that removed exons 1 to 3 of UFD1L was found in one individual with features typical of 22q11 deletion syndrome. These data suggest that UFD1L haploinsufficiency contributes to the congenital heart and craniofacial defects seen in 22q11 deletion.  (+info)

The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation. (2/4396)

1. Arachidonic acid (0.01-1 microM) induced relaxation of precontracted rings of rabbit saphenous vein, which was counteracted by contraction at concentrations higher than 1 microM. Concentrations higher than 1 microM were required to induce dose-dependent contraction of vena cava and thoracic aorta from the same animals. 2. Pretreatment with a TP receptor antagonist (GR32191B or SQ29548, 3 microM) potentiated the relaxant effect in the saphenous vein, revealed a vasorelaxant component in the vena cava response and did not affect the response of the aorta. 3. Removal of the endothelium from the venous rings, caused a 10 fold rightward shift in the concentration-relaxation curves to arachidonic acid. Whether or not the endothelium was present, the arachidonic acid-induced relaxations were prevented by indomethacin (10 microM) pretreatment. 4. In the saphenous vein, PGE2 was respectively a 50 and 100 fold more potent relaxant prostaglandin than PGI2 and PGD2. Pretreatment with the EP4 receptor antagonist, AH23848B, shifted the concentration-relaxation curves of this tissue to arachidonic acid in a dose-dependent manner. 5. In the presence of 1 microM arachidonic acid, venous rings produced 8-10 fold more PGE2 than did aorta whereas 6keto-PGF1alpha and TXB2 productions remained comparable. 6. Intact rings of saphenous vein relaxed in response to A23187. Pretreatment with L-NAME (100 microM) or indomethacin (10 microM) reduced this response by 50% whereas concomitant pretreatment totally suppressed it. After endothelium removal, the remaining relaxing response to A23187 was prevented by indomethacin but not affected by L-NAME. 7. We conclude that stimulation of the cyclo-oxygenase pathway by arachidonic acid induced endothelium-dependent, PGE2/EP4 mediated relaxation of the rabbit saphenous vein. This process might participate in the A23187-induced relaxation of the saphenous vein and account for a relaxing component in the response of the vena cava to arachidonic acid. It was not observed in thoracic aorta because of the lack of a vasodilatory receptor and/or the poorer ability of this tissue than veins to produce PGE2.  (+info)

Enantioselective inhibition of the biotransformation and pharmacological actions of isoidide dinitrate by diphenyleneiodonium sulphate. (3/4396)

1. We have shown previously that the D- and L- enantiomers of isoidide dinitrate (D-IIDN and L-IIDN) exhibit a potency difference for relaxation and cyclic GMP accumulation in isolated rat aorta and that this is related to preferential biotransformation of the more potent enantiomer (D-IIDN). The objective of the current study was to examine the effect of the flavoprotein inhibitor, diphenyleneiodonium sulphate (DPI), on the enantioselectivity of IIDN action. 2. In isolated rat aortic strip preparations, exposure to 0.3 microM DPI resulted in a 3.6 fold increase in the EC50 value for D-IIDN-induced relaxation, but had no effect on L-IIDN-induced relaxation. 3. Incubation of aortic strips with 2 microM D- or L-IIDN for 5 min resulted in significantly more D-isoidide mononitrate formed (5.0 +/- 1.5 pmol mg protein(-1)) than L-isoidide mononitrate (2.1 +/- 0.7 pmol mg protein(-1)) and this difference was abolished by pretreatment of tissues with 0.3 microM DPI. DPI had no effect on glutathione S-transferase (GST) activity or GSH-dependent biotransformation of D- or L-IIDN in the 105,000 x g supernatant fraction of rat aorta. 4. Consistent with both the relaxation and biotransformation data, treatment of tissues with 0.3 microM DPI significantly inhibited D-IIDN-induced cyclic GMP accumulation, but had no effect on L-IIDN-induced cyclic GMP accumulation. 5. In the intact animal, 2 mg kg(-1) DPI significantly inhibited the pharmacokinetic and haemodynamic properties of D-IIDN, but had no effect L-IIDN. 6. These data suggest that the basis for the potency difference for relaxation by the two enantiomers is preferential biotransformation of D-IIDN to NO, by an enzyme that is inhibited by DPI. Given that DPI binds to and inhibits NADPH-cytochrome P450 reductase, the data are consistent with a role for the cytochromes P450-NADPH-cytochrome P450 reductase system in this enantioselective biotransformation process.  (+info)

Effect of acute and long-term treatment with 17-beta-estradiol on the vasomotor responses in the rat aorta. (4/4396)

1. This study sought to evaluate whether the effects of acute and long-term treatment with 17-beta-estradiol on the vasomotor responses in rat aortic rings are mediated through the same mechanism. 2. Ovariectomized rats were treated daily with either 17-beta-estradiol-3-benzoate (100 microg kg(-1)) or vehicle for 1 week. 3. The effect of long-term 17-beta-estradiol treatment on the responses to cumulative doses of phenylephrine, 5-HT, calcium, potassium and 17-beta-estradiol was determined in aortic rings. In the same rings, the effect of acute exposure to 17-beta-estradiol (5 and 10 microM) on the dose response curves for phenylephrine, 5-HT, calcium, potassium and acetylcholine were estimated. The measurements were made in rings with and without intact endothelium. The tone-related basal release of nitric oxide (NO) was measured in rings with intact endothelium. 4. Long-term 17-beta-estradiol treatment reduced the maximum developed contraction to all contracting agents studied. This effect was abolished in endothelium denuded vessels. Acute 17-beta-estradiol treatment also reduced maximal contraction. This effect, however, was independent of the endothelium. 5. Long-term 17-beta-estradiol treatment significantly increased the ability of the rings to dilate in response to acetylcholine whereas acute exposure to 17-beta-estradiol had no effect. The tone-related release of NO was significantly increased after long-term exposure to 17-beta-estradiol. 6. In conclusion, this study indicate that the acute and long-term effects of 17-beta-estradiol in the rat aorta are mediated through different mechanisms. The long-term effect is mediated through the endothelium most likely by increasing NO release. In contrast, the acute effect of 17-beta-estradiol seems to be through an effect on the vascular smooth muscle cells.  (+info)

Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. (5/4396)

1. The mechanisms of the sustained vasodilator actions of corticotrophin-releasing factor (CRF) and sauvagine (SVG) were studied using rings of endothelium de-nuded rat thoracic aorta (RTA) and the isolated perfused rat superior mesenteric arterial vasculature (SMA). 2. SVG was approximately 50 fold more potent than CRF on RTA (EC40: 0.9 +/- 0.2 and 44 +/- 9 nM respectively, P < 0.05), and approximately 10 fold more active in the perfused SMA (ED40: 0.05 +/- 0.02 and 0.6 +/- 0.1 nmol respectively, P < 0.05). Single bolus injections of CRF (100 pmol) or SVG (15 pmol) in the perfused SMA caused reductions in perfusion pressure of 23 +/- 1 and 24 +/- 2% that lasted more than 20 min. 3. Removal of the endothelium in the perfused SMA with deoxycholic acid attenuated the vasodilatation and revealed two phases to the response; a short lasting direct action, and a sustained phase which was fully inhibited. 4. Inhibition of nitric oxide synthase with L-NAME (100 microM) L-NMMA (100 microM) or 2-ethyl-2-thiopseudourea (ETPU, 100 microM) had similar effects on the vasodilator responses to CRF as removal of the endothelium, suggesting a pivotal role for nitric oxide. However the selective guanylate cyclase inhibitor 1H-[l,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ, 10 microM) did not affect the response to CRF. 5. High potassium (60 mM) completely inhibited the vasodilator response to CRF in the perfused SMA, indicating a role for K channels in this response. 6. Compared to other vasodilator agents acting via the release of NO, the actions of CRF and SVG are strikingly long-lasting, suggesting a novel mechanism of prolonged activation of nitric oxide synthase.  (+info)

Protective effect of dietary tomato against endothelial dysfunction in hypercholesterolemic mice. (6/4396)

The effects of dietary ingestion of tomato were studied in mice that had been made hypercholesterolemic by feeding atherogenic diets. Mice which had been fed on the atherogenic diet without tomato for 4 months had significantly increased plasma lipid peroxide, and the vaso-relaxing activity in the aorta induced by acetylcholine (ACh) was harmed when compared with mice fed on a common commercial diet. On the other hand, mice which had been fed on the atherogenic diet containing 20% (w/w) lyophilized powder of tomato showed less increase in the plasma lipid peroxide level, and ACh-induced vaso-relaxation was maintained at the same level as that in normal mice. These results indicate that tomato has a preventive effect on atherosclerosis by protecting plasma lipids from oxidation.  (+info)

Effects of docosahexaenoic and eicosapentaenoic acid on lipid metabolism, eicosanoid production, platelet aggregation and atherosclerosis in hypercholesterolemic rats. (7/4396)

Exogenously hypercholesterolemic (ExHC) rats were fed on an atherogenic diet supplemented with 1% each of either ethyl ester docosahexaenoic acid [EE-DHA, 22:6(n-3)], ethyl ester eicosapentaenoic acid [EE-EPA, 20:5(n-3)] or safflower oil (SO) for 6 months. The rats fed on the diets containing EE-EPA or EE-DHA, compared with those fed on SO, had lower serum cholesterol and triacylglycerol levels, less aggregation of platelets and slower progress of intimal thickening in the ascending aorta. Relative to the SO-fed rats, both of the (n-3) fatty acid-fed rats had a significantly reduced proportion of arachidonic acid in the platelet and aortic phospholipids, and lower production of thromboxane A2 by platelets and of prostacyclin by the aorta. These results suggest that EPA and DHA are similarly involved in preventing atherosclerosis development by reducing hypercholesterolemia and modifying the platelet functions.  (+info)

Modulation of temperature-induced tone by vasoconstrictor agents. (8/4396)

One of the primary cardiovascular adjustments to hyperthermia is a sympathetically mediated increase in vascular resistance in the viscera. Nonneural factors such as a change in vascular tone or reactivity may also contribute to this response. Therefore, the aim of this study was to determine whether vascular smooth muscle tone is altered during heating to physiologically relevant temperatures >37 degrees C. Gradually increasing bath temperature from 37 degrees C (normothermia) to 43 degrees C (severe hyperthermia) produced graded contractions in vascular ring segments from rat mesenteric arteries and thoracic aortae. In untreated rings these contractions were relatively small, whereas hyperthermia elicited near-maximal increases in tension when rings were constricted with phenylephrine or KCl before heating. In phenylephrine-treated mesenteric arterial rings, the contractile responses to heating were markedly attenuated by the Ca2+ channel antagonists nifedipine and diltiazem. Diltiazem also blocked the contractile responses to heating in thoracic aortic rings. These results demonstrate that hyperthermia has a limited effect on tension generation in rat vascular smooth muscle in the absence of vascular tone. However, in the presence of agonist-induced tone, tension generation during heating is markedly enhanced and dependent on extracellular Ca2+. In conclusion, these data suggest that local regulation of vascular tone can contribute to the hemodynamic adjustments to hyperthermia.  (+info)

AORTIC ARCH ANOMALIES. Dr.Santhosh Narayanan. Topic outline. Embryology Anatomy Classification Individual anomalies. Embryology-Sequence of Events. Day I8 - Cardiac precursor cells seen in the form of blood islands Day 20 - First intraembryonic blood vessels Slideshow 1406753 by gwyneth
The descending thoracic aorta arises from the aortic arch just after the origin of the left subclavian artery, at the inferior border of the fourth thoracic vertebrae. This point of transition is termed the aortic isthmus. In adults, the average diameter of the descending thoracic aorta is 2.8 cm in men and 2.6 cm in women.2 This narrows as it descends into the abdomen. It terminates as it enters the abdomen via the diaphragmatic aortic hiatus, at the 12th intercostal space. The thoracic aorta descends in the posterior mediastinum to the left of the vertebral column and gradually shifts to the midline at the aortic hiatus. It is surrounded by the thoracic aortic plexus. Anteriorly, the left pulmonary hilum crosses with the left main bronchus and left pulmonary artery being closely associated. Continuing inferiorly, the esophagus, pericardium, and diaphragm are also situated at the anterior border of the thoracic aorta. As the thoracic aorta descends, the esophagus crosses anteriorly and then ...
BioAssay record AID 602900 submitted by ChEMBL: Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM after 10 to 60 mins.
After exposure, all rats were killed and the thoracic aorta was isolated. 3-4 mm long aorta rings were prepared and placed in a bath with test solution including either a vasoconstrictor (10-7 M phenylephrine) or vasodilator (10-6 M acetylcholine or 10-6 M sodium nitroprusside, respectively). ...
BioAssay record AID 568587 submitted by ChEMBL: Vasodilatory activity in Sprague-Dawley rat thoracic aorta smooth muscle assessed as inhibition of phenylephrine-induced vasoconstriction.
Transmural concentration profiles of 125I-albumin in vivo were measured across the normal and balloon catheter-deendothelialized rabbit descending thoracic aorta as a function of time following intravenous injection. A tracer was injected 5 or 60 minutes after deendothelialization, and the animals were sacrificed after circulation times of 10, 30 or 60 minutes. The aorta was immediately excised and frozen flat between glass slides. Samples were serially sectioned parallel to the intimal surface in a refrigerated microtome, washed with trichloroacetic acid (TCA), and counted. Relative tissue concentration profiles of TCA-precipitable radioactivity from the media of control animals showed entry from both luminal and adventitial sides, as previously found with conscious normal rabbits, but spatial gradients at both luminal and medial-adventitial borders were less steep. Relative concentration levels in ballooned animals were 10- to 40-fold higher than in controls, and the profiles were flatter. ...
New pharmacotherapies are required to improve vessel graft protection and prevent vasoconstriction and spasm in CABG surgery. Previously we have studied adenosine (A) and lidocaine (L) relaxation in rat aortic rings, and reported a possible crosstalk between L relaxation and adenosine A(2a) receptor inhibition. The aim of the present study was to examine the effect of AL combination compared to A and L alone on relaxation in intact and denuded rat aortic rings and in guinea-pig pressurized mesenteric arterial segments. Aortic rings were harvested from Sprague-Dawley rats and equilibrated in an organ bath containing modified Krebs-Henseleit (KH) solution, pH 7.4, 37 degrees C. Rings were pre-contracted sub-maximally with 0.3 mu M norepinephrine, and the effects of increasing AL, A or L (up to 1.0 mM) were examined in intact and denuded rings. Mesenteric artery segments were isolated from guinea-pigs and mounted in an arteriograph containing KH solution and pressurised to 60 mmHg. Arteries were ...
Hey all. Im not here often as my kiddos issue was minor (ASD) and diagnosed at 6 months. It was just a waiting game to see if it would close until her 4 year check, which just occurred on 9/6. At that time, she had a complete echocardiogram, which had not been done since she was diagnosed with the ASD at 6 months - reason being is her pediatric cardio wasnt going to intervene until she hit 40 lbs., so he didnt think it was necessary. She always had an EKG at her check-ups, and that was it. Anywho, she had the echo and needless to say, my very hyper daughter was not the best patient. They seemed to take forever. They were taking shots off and on for about 1.5 hours. Tech called in cardiologist who was trying to get a shot, but having trouble as well. Finally, cardiologist tells us that the ASD is closed. I say - wait, even *I* can still here her murmur clear as day. She says, We need to talk. We go in and she draws a picture and explains in too simple terms that Lauren has a right
Transesophageal MRI of human thoracic aortae demonstrate the feasibility of the technique in healthy volunteers (Fig. 2A)and among patients with aortic atherosclerosis (Fig. 2B-D). Figure 2C, Dshows the corresponding TEMRI and TEE images of the distal aortic arch in a 77-year-old male patient with remote stroke, depicting heterogeneous atherosclerotic thickening, and this illustrates differences in circumferential plaque extent by the two methods. Figure 2Eis a longitudinal slice through the descending thoracic aorta and a portion of the arch of a normal subject, demonstrating the nonuniform SNR of the device (9,12). The SNR decreases linearly with radial distance from the probe, but substantially maintains its SNR along much of its length. In practical terms, this property allows TEMRI at multiple longitudinal locations over ∼20 cm without the need for repositioning the device.. Maximum and minimum WTs were 3.5 ± 1.2 mm and 1.2 ± 0.8 mm by TEE, and 3.3 ± 1.5 mm and 1.0 ± 0.7 mm by TEMRI, ...
Endovascular repair of the thoracic aorta has been adopted as the first-line therapy for much pathology. Initial results from the early-generation endografts have highlighted the potential of this technique. Newer-generation endografts have now been introduced into clinical practice and careful assessment of their performance should be mandatory. This study describes the initial experience with the Valiant endograft and makes comparisons with similar series documenting previous-generation endografts. Data were retrospectively collected on 180 patients treated with the Valiant endograft at seven European centers between March 2005 and October 2006. The patient cohort consisted of 66 patients with thoracic aneurysms, 22 with thoracoabdominal aneurysms, 19 with an acute aortic syndrome, 52 with aneurysmal degeneration of a chronic dissection, and 21 patients with traumatic aortic transection. The overall 30-day mortality for the series was 7.2%, with a stroke rate of 3.8% and a paraplegia rate of 3.3%.
Published in: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (ISSN: 1078-5884), vol. 26, num. 2, p. 195-204 ...
TY - JOUR. T1 - Unexpected thrombus migration obstructing the right coronary ostium after thoracic aorta graft replacement. AU - Shim, Jae Kwang. AU - Song, Young. AU - Lee, Taek Yeon. AU - Kim, Yoon Jae. AU - Kwak, Young Lan. PY - 2014/6. Y1 - 2014/6. N2 - Unexpected and reversible causes of ventricular dysfunction requiring a prompt second surgical procedure to restore the cardiac function should always be sought before the initiation of positive inotropic support. We report a case of obstruction of the right coronary ostium by an organized thrombus that had migrated retrogradely from the false lumen of a dissected aortic aneurysm. The resultant ventricular dysfunction hindered separation from cardiopulmonary bypass. Prompt recognition was done by transesophageal echocardiography and a second surgical procedure was immediately performed to remove the thrombus before irreversible ventricular dysfunction occurred.. AB - Unexpected and reversible causes of ventricular dysfunction requiring a ...
With the advent of helical CT, the capability of noninvasive imaging of the thoracic aorta has been enhanced considerably. In this article, we describe the potential of helical CT using dual-slice technology to evaluate thoracic aortic diseases such
Fingerprint Dive into the research topics of Unexpected thrombus migration obstructing the right coronary ostium after thoracic aorta graft replacement. Together they form a unique fingerprint. ...
ICD-10-PCS code 021X0ZD for Bypass Thoracic Aorta, Ascending/Arch to Carotid, Open Approach is a medical classification as listed by CMS under Heart and Great Vessels range.
ICD-10-PCS code 021X4JD for Bypass Thoracic Aorta, Ascending/Arch to Carotid with Synthetic Substitute, Percutaneous Endoscopic Approach is a medical classification as listed by CMS under Heart and Great Vessels range.
Multimodality imaging of diseases of the thoracic aorta in adults: from the American Society of Echocardiography and the European Association of Cardiovascular Imaging: endorsed by the Society of Cardiovascular Computed Tomography and Society for Cardiovascular Magnetic Resonance
TY - JOUR. T1 - Treatment of dissecting aneurysms of the descending thoracic aorta.. AU - Juanteguy, J. M.. AU - Wilder, R. J.. PY - 1970/8. Y1 - 1970/8. UR - UR - M3 - Article. C2 - 5450420. AN - SCOPUS:0014836896. VL - 36. SP - 493. EP - 498. JO - American Surgeon. JF - American Surgeon. SN - 0003-1348. IS - 8. ER - ...
FIGURE 1. (A) Schematic setup of the stereo-vision system to focus on a specimen, (B) specimen images taken by each camera, and (C) the reconstructed positions of markers affixed to the specimen in the 3D coordinate system. [Color figure can be viewed in the online issue, which is available at] - Longitudinal differences in the mechanical properties of the thoracic aorta depend on circumferential regions.
The thoracic aorta begins at the level of vertebra T5 and continues through to the diaphragm at the level of T12, initially traveling within the mediastinum to the left of the
CT - Angiograms - Thoracic aorta angiogram is a way of looking at the blood vessels in different parts of your body. Learn more about this procedure.
The aorta originates from the left ventricle of the heart. It ends in the abdomen where it branches into the two common iliac arteries. The aorta has five separate segments. The descending aorta begins at the arch of the aorta (where it loops over the heart to begin its descent).
Bevezetés: Az arteriosclerosis generalizált érbetegség, de egyes verőérszakaszokon eltérő súlyossággal jelentkezhet. Speciális ritka megjelenési formája az aorta atheromás fekélyképződése, ami hajlamosít subintimalis bevérzésre, dissectióra, álaneurysma-képződésre és rupturára (akut aortaszindróma). Célkitűzés: A szerzők célja a kórkép kezelésével szerzett tapasztalatok ismertetése. Módszer: A szerzők osztályán 10 212, szív-ér rendszeri betegség miatt operált beteg közül 18 esetben találtak penetráló ulcust a thoracalis aorta különböző szakaszain. Az aorta ascendensen, az aortaíven, az aorta descendensen és thoracoabdominalis aortán kialakult elváltozásokat több esetben számos társbetegség súlyosbította. Nyolc beteg tünetekkel, 10 tünetmentes állapotban került felfedezésre. Eredmények: A lokalizációtól függően megválasztott nyitott (n = 4), hibrid (n = 7) és endovascularis (n = 7) beavatkozásokat végeztek. A korai ...
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02UX4KZ ICD-10 PCS Code descriptor cic Aorta, Ascending/Arch with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
Xinmai Medical (688016) In-depth report: Domestic aorta and prolonged vascular intervention faucet. Report Summary Xinmai Xinmai Medical is currently the leading domestic manufacturer of aortic and vascular interventional products, with rich products and leading market share.. The company developed and launched the worlds first split-type stent graft in the field of thoracic aorta stent grafts. In the field of abdominal aortic stent grafts, although there is still a gap with imported products, it is gradually upgraded and is expected to achieve import substitution.. The layout of distal vascular interventional devices is extensive and rich. Drug replacement balloons have been applied for marketing, and the market potential has broken through.. The company has rich research reserves, continuous high-intensity research and development, and expansion of innovation capabilities. It is a leader in aortic intervention and interventional vascular 苏州桑拿网 disease segmentation.. The domestic ...
Abe and associates reported the trends in the early outcomes of surgical repair for acute type A aortic dissection in 11,843 patients from the Japan Cardiovascular Surgery Database between 2008 and 2015. Operative mortality was 9.5% and 30-day mortality was 7.6%. The number of surgically treated cases increased by 45% during the interval ...
In the previous studies, extensive accumulation and slower elimination of radioactivity from the eyeball and thoracic aorta were observed when 14C-YM758 was orally administered to nonalbino rats and/or albino rats. In albino rats, the plasma concentrations of the unchanged drug were detected only at 0.5 and 1 h, and the area under the curve extrapolated to 1 h ratio between the plasma concentrations of radioactivity and the unchanged drug was estimated to be 17.7%, indicating the existence of YM758 metabolites in rat plasma (Umehara et al., 2008f). In rat plasma, R1 (YM-385462), R2 (YM-385463), R3 (YM-385459), R4 (YM-252124), R9 (YM-234903), R10 and R19 (YM-396944) were detected as YM758 metabolites from radio-HPLC analyses (Fig. 4) (N. Nakada, Y. Susaki, T. Yokota, K. I. Umehara, T. Sonoda, E. Nakamura, T. Usui, T. Iwatsubo, and H. Kamimura, manuscript submitted for publication; Umehara et al., 2009a,b). Considering the previous findings and discussion on YM758 metabolites detected in rat ... - en side om ultralydsundersøgelse af hjertet. Af Dansk Cardiologisk Selskabs arbejdsgruppe vedr. ekkokardiografi.
TY - JOUR. T1 - Selective cerebral perfusion with 4-branch graft total aortic arch replacement. T2 - Outcomes in 12 patients. AU - Lai, Wei Liang. AU - Hsu, Chiao Po. AU - Shih, Chung Che. AU - Li, Ming Li. AU - Li, Ping chun. PY - 2012/4/13. Y1 - 2012/4/13. N2 - Background: Aortic arch reconstruction is associated with high neurological morbidity. Our purpose is to describe our experience using a 4-branched graft and selective antegrade brain perfusion (SABP) for total aortic arch replacement (TAR).Methods: We retrospectively reviewed the medical records of 12 patients who received TAR, with or without ascending aorta replacement, with a 4-branched graft for Stanford type A dissection (n = 9) or aortic arch aneurysm (n = 3). In all patients surgery was performed with deep hypothermic circulatory arrest (DHCA) with or without retrograde brain perfusion, and selective antegrade brain perfusion (SABP) via the subclavian artery or axillary artery.Results: There were 8 males and 4 females with an ...
TY - JOUR. T1 - Gadolinium-enhanced 3D MRA of the aortic arch vessels the detection of atherosclerotic cerebrovascular occlusive disease. AU - Krinsky, Glenn. AU - Maya, Menahem. AU - Rofsky, Neil. AU - Lebowitz, Jonathan. AU - Nelson, Peter Kim. AU - Ambrosino, Michael. AU - Kaminer, Evan. AU - Earls, Jay. AU - Masters, Lynette. AU - Giangola, Gary. AU - Litt, Andrew. AU - Weinreb, Jeffrey. PY - 1998/4/18. Y1 - 1998/4/18. N2 - Purpose: Our goal was to evaluate non-breath-hold Gd-enhanced 3D MR angiography (MRA) for the detection of atherosclerotic occlusive disease of the aortic arch vessels and to compare image quality with two breath-hold techniques. Method: One hundred sixty consecutive patients with known or clinically suspected atherosclerotic cerebrovascular occlusive disease underwent Gd-enhanced 3D MRA of the aortic arch and great vessels. One hundred twenty-six examinations were performed with the body coil after infusion of 40 ml of Gd-DTPA; 89 of these were performed without breath- ...
A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Aortic arch interruption
TY - JOUR. T1 - Total arch replacement with endarterectomy of the ascending aorta in a patient with aortic arch aneurysm and porcelain aorta. AU - Shimizu, Hideyuki. AU - Miyaki, Yasuko. AU - Kaneko, Tsuyoshi. AU - Suzuki, Ryo. AU - Kudo, Mikihiko. AU - Yozu, Ryohei. PY - 2008/12/1. Y1 - 2008/12/1. N2 - We describe total arch replacement for aortic arch aneurysm with a severely calcified (porcelain) aorta. Cardiovascular surgery is challenging under such conditions because the calcified plate interferes with clamping, incising, and suturing of the aorta. We performed this surgery under hypothermic circulatory arrest with antegrade cerebral perfusion. Calcification manifested particularly in the ascending aorta and prevented the use of a needle. We exfoliated the calcified intimal plate using an elevator designed for hand surgery, and then covered both the inner and outer sides of the endarterectomized aorta with a strip of bovine pericardium to reinforce the anastomotic region and cover the ...
This study was designed to determine whether the endothelium-derived relaxing factor induced by acetylcholine (1 microM) in rabbit thoracic aorta inhibits agonist-induced calcium mobilization, specifically calcium influx. Force generated in rings of rabbit thoracic aorta by norepinephrine (1 microM) was measured under isometric conditions. At the appropriate time during 1 microM acetylcholine-induced relaxation of 1 microM norepinephrine-contracted rabbit thoracic aorta, the rings were pulse-labelled with calcium-45 to measure calcium influx. When measured in this fashion, 1 microM acetylcholine decreased the 1 microM norepinephrine-induced increase in calcium influx. This effect was eliminated by removal of the endothelium and by atropine (1 microM), but not by indomethacin (14 microM). Acetylcholine (1 microM) also blocked the 60 mM potassium-chloride-induced increase in calcium influx without dramatically affecting force. The phasic contraction produced by norepinephrine (1 microM) with 2 mM ...
METHODS AND RESULTS Normal or hypercholesterolemic rabbits received intravenous L-arginine (10 mg/kg/min) or vehicle for 70 minutes. Subsequently, animals were killed, thoracic aortas were harvested, and vascular rings were studied in vitro. Rings were contracted by norepinephrine and relaxed by acetylcholine chloride or sodium nitroprusside. Vasorelaxation was quantified by determining the maximal response (expressed as percent relaxation of the contraction) and the ED50 (dose of drug inducing 50% relaxation; expressed as -log M). In vessels from hypercholesterolemic animals receiving vehicle, there was a fivefold rightward shift in sensitivity to acetylcholine compared with normal animals (p = 0.05, n = 5 in each group). In vessels from hypercholesterolemic animals, L-arginine augmented the maximal response to acetylcholine (83 +/- 16% versus 60 +/- 15%, p = 0.04 versus vehicle) and increased the sensitivity to acetylcholine (ED50 value: 6.7 +/- 0.2 versus 6.2 +/- 0.2, p less than 0.05 versus ...
TY - JOUR. T1 - Ascending thoracic aorta. T2 - Postoperative imaging evaluation. AU - Prescott-Focht, Julia A.. AU - Martinez-Jimenez, Santiago. AU - Hurwitz, Lynne M.. AU - Hoang, Jenny K.. AU - Christensen, Jared D.. AU - Ghoshhajra, Brian B.. AU - Abbara, Suhny. N1 - Copyright: Copyright 2013 Elsevier B.V., All rights reserved.. PY - 2013/1. Y1 - 2013/1. N2 - Advances in computed tomography (CT) scanners and electrocardio-graphic gating techniques have resulted in superior image quality of the ascending aorta and increased the use of CT angiography for evaluating the postoperative ascending aorta. Several abnormalities of the ascending aorta and aortic arch often require surgery, and various open techniques may be used to reconstruct the aorta, such as the Wheat procedure, in which both an ascending aortic graft and an aortic valve prosthesis are implanted; the Cabrol and modifed Bentall procedures, in which a composite synthetic ascending aorta and aortic valve graft are placed; the Ross ...
PURPOSE: Traumatic rupture of the thoracic aorta secondary to blunt chest trauma is a life-threatening emergency and a common cause of death, usually following violent collisions. The objective of this retrospective report was to evaluate the efficacy of endovascular treatment of thoracic aortic disruptions with a single commercially available stent-graft.. METHODS: Nine men (mean age 29.5 years) were admitted to our institution between January 2003 and January 2006 due to blunt aortic trauma following violent motor vehicle collisions. Plain chest radiography, spiral computed tomography, aortography, and transesophageal echocardiography were used for diagnostic purposes in all cases. All patients were diagnosed with contained extramural thoracic aortic hematomas, secondary to aortic disruption. One patient was also diagnosed with a traumatic thoracic aortic dissection, secondary to blunt trauma. All subjects were poor surgical candidates, due to major injuries such as multiple bone fractures, ...
Abstract Transesophageal echocardiography (TEE) is a key diagnostic modality in patients with acute aortic dissections, yet its sensitivity is limited by the blind-spot caused by air in the trachea. After placement of a fluid-filled balloon in the trachea visualization of the thoracic aorta becomes possible. This method, modified TEE, has been shown to be an accurate test for the diagnosis of upper aortic atherosclerosis.. In this study it was demonstrated that modified TEE can reveal the blind-spot of conventional TEE. In patients with (suspected) aortic dissection it is thus possible to obtain a complete echocardiographic overview of the thoracic aorta and its branches. This is of specific merit in hemodynamically unstable patients who cannot undergo CT. Modified TEE can also guide the surgical management and monitor perfusion of cerebral arteries.. Click on the picture to read the article.. ...
Patients involved in high-energy blunt trauma involving rapid deceleration are at significant risk for blunt aortic injury. The majority of blunt aortic injuries are due to motor vehicle collision. In the United States, blunt aortic injury is the sec
TY - GEN. T1 - Ascending thoracic aorta exhibits anisotropic failure behavior in shear lap testing. AU - Witzenburg, Colleen. AU - Shah, Sachin. AU - Wagner, Hallie P.. AU - Goodrich, Janna. AU - Barocas, Victor H. PY - 2013/12/1. Y1 - 2013/12/1. UR - UR - U2 - 10.1115/SBC2013-14413. DO - 10.1115/SBC2013-14413. M3 - Conference contribution. AN - SCOPUS:84894670288. SN - 9780791855607. VL - 1 A. BT - ASME 2013 Summer Bioengineering Conference, SBC 2013. T2 - ASME 2013 Summer Bioengineering Conference, SBC 2013. Y2 - 26 June 2013 through 29 June 2013. ER - ...
TY - JOUR. T1 - Near-infrared spectroscopy during hypothermic selective cerebral perfusion--a clinical study of its value. AU - Ito, T.. AU - Ueda, T.. AU - Omoto, T.. AU - Moro, K.. AU - Mitsumaru, A.. AU - Goto, T.. AU - Yozu, R.. AU - Kawada, S.. PY - 1998/12. Y1 - 1998/12. N2 - The purpose of this study is to assess the value of near-infrared spectroscopic oxymetry (NIRO) in monitoring cerebral oxygenation and metabolism during selective cerebral perfusion (SCP) for surgery of the aortic arch. The measurement protocol during SCP comprised oxyhemoglobin (HbO2), deoxyhemoglobin (Hb), and total hemoglobin levels in the brain. From March 1994 through March 1997, 14 patients underwent surgical treatment of the aortic arch anomalies with intraoperative monitoring with NIRO. The temporary circulatory arrest was accomplished at a rectal temperature of 22 degrees C and the hypothermic SCP was employed for the cerebral protection. SCP was initiated at a flow rate of 10 ml/kg/min so as to maintain HbO2 ...
Right aortic arch with aberrant left subclavian artery (RAA/aLSCA) is a rare aortic arch anomaly. The clinical association of aLSCA stenosis with RAA/aLSCA has not yet been fully elucidated. The aim of this study was to investigate the diagnosis, incidence, management and outcome of aLSCA stenosis in infants with prenatally diagnosed RAA/aLSCA. Ten fetuses who were diagnosed as having RAA/aLSCA in Kyushu University Hospital between January 2011 and December 2014 were enrolled. The maternal and child medical records were reviewed to investigate sex, gestational age at the fetal diagnosis, gestational age and body weight at birth, the findings of computed tomography (CT), Doppler ultrasonography of the vertebral artery and angiography, and the complications and outcomes of aLSCA stenosis ...
Sigma-Aldrich offers abstracts and full-text articles by [Ga-Young Suh, Ramin E Beygui, Dominik Fleischmann, Christopher P Cheng].
Trauma professionals routinely worry about the thoracic aorta when evaluating adults after major blunt trauma. The question is, how much do we have to worry about blunt thoracic aortic injury in children?. Younger children are more elastic, and their organs tend to withstand more punishment than adults. After reviewing the literature, Ive come to the conclusion that this injury is very rare in children in the single digit age range. Its difficult to find a good paper that addresses this question. The majority include kids up to age 16 or 18, which really skews the results. These patients are most commonly involved in motor vehicle crashes, although a significant number are also pedestrians struck by cars. The National Trauma Data Bank (NTDB) was queried for all children ,18 years old sustaining blunt injury with at least 1 diagnosis code. There were nearly 27,000 records matching these criteria. Of these, only 34 had an injury to the thoracic aorta. And in the age range under 10, there were ...
This study was designed to determine whether the relaxant effect of apigenin was endothelium dependent and to examine the possible antiproliferative effect of apigenin. Apigenin relaxed the phenylephrine-precontracted endothelium-intact aortic rings with IC50 value of 3.7+/-0.5 muM and removal of a functional endothelium significantly attenuated this relaxation (IC50 = 8.2+/-0.9 muM). However, apigenin did not affect the 0.1 muM phorbol 12,13-dibutyrate-induced contraction (IC50 = 34.6 +/- 1.2 muM) within the concentration range that relaxed the phenylephrine-contracted arteries, suggesting that apigenin did not influence protein kinase C-mediated contractile mechanisms in rat aorta. Pretreatment of apigenin significantly potentiated the relaxant effect of acetylcholine on phenylephrine-induced contraction. Pretreatment with N-G-nitro-L-arginine methyl ester (L-NAME) or methylene blue reduced the relaxant effect of apigenin. Apigenin (10 muM) increased the guanosine 3′,5′-cyclic ...
The major artery carrying blood from the heart to blood vessels throughout the body, the aorta is about one inch in diameter. From the heart, the thoracic aorta extends upward (ascending aorta) before arching (aortic arch) and extending downward through the chest (descending aorta). Along the way, arteries branching from the thoracic aorta supply oxygen-rich blood to the heart muscle, head and neck, arms, and chest. Thoracic surgeons such as Dr. Raissi specialize in repair and replacement techniques for the ascending aorta, aortic arch and descending aorta - those within the chest cavity. When the aorta passes through the diaphragm and into the abdomen, it becomes known as the abdominal aorta and its arteries supply blood to the abdomen and lower extremities. A localized weakness or bulge in the aorta - an aneurysm - can become life-threatening if it ruptures, and victims often have few, if any, noticeable warning signs. Although prolonged high blood pressure and arterial plaque buildup are ...
Acute infectious pseudoaneurysm of the descending thoracic aorta and review of infectious aortitis. Vasc Endovascular Surg. 2010 Nov; 44(8):697-700 ...
Aortic arch reconstruction using the main pulmonary artery and ascending aorta, atrial septectomy, and modified Blalock-Taussig shunt provides unobstructed systemic blood flow and adequate coronary artery perfusion ...
Definition of esophageal branches of the thoracic aorta. Provided by Stedmans medical dictionary and Includes medical terms and definitions.
Background: Large aortic arch plaques are associated with ischemic stroke. Carotid intima-media thickness (CIMT) is a marker of subclinical atherosclerosis and a strong predictor of cardiovascular disease and stroke. The association between CIMT and aortic arch plaques has been studied in patients with strokes, but not in the general population. The aim of this study was to investigate this association in an elderly asymptomatic cohort and to assess the possibility of using CIMT to predict the presence or absence of large aortic arch plaques. ...
The aorta is the largest artery in your body, and it carries blood away from your heart to all the parts of your body. The part of your aorta that runs through your chest is called the thoracic aorta and, when your aorta reaches your abdomen, it is called the abdominal aorta. When a weak area of your thoracic aorta expands or bulges, it is called a thoracic aortic aneurysm (TAA).
Abnormally stiffened arteries are present in individuals with diabetes and are associated with an increase in cardiovascular events, LV afterload, and exercise intolerance (1,4,9). In this study, we sought to determine if individuals with IFG exhibited abnormal stiffening of the arterial tree (including the proximal thoracic aorta) that in studies of individuals with diabetes is associated independently with adverse cardiovascular events. There are two important findings in this study: Total vascular stiffness is worse in subjects with IFG compared with those with NFG. This finding is true regardless of age, sex, ethnicity, or other factors associated with abnormal vascular stiffening (Table 2; Fig. 2). After adjustment for factors known to influence vascular stiffness, proximal thoracic aortic stiffness and LV mass are similar in individuals with IFG and NFG (Figs. 3 and 4). In patients with diabetes, however, both proximal thoracic aortic stiffness and LV mass are elevated (Figs. 3 and ...
A new potent, selective and p.o. active serotonergic [5-hydroxytryptamine (5-HT2)] receptor antagonist, SR 46349B [trans, 4-([3Z)3-(2-dimethylaminoethyl)oxyimino-3(2-flurophenyl++ +)propen-1-yl]phenol hemifumarate) has been characterized by a series of in vitro and in vivo methods. Based upon binding studies with 5-HT2 receptors in rat brain cortical membranes and blockade of 5-HT-induced contractions in isolated tissues (rabbit thoracic aorta, rat jugular vein, rat caudal artery, rat uterus and guinea pig trachea), SR 46349B showed high affinity for 5-HT2 receptors. Furthermore, SR 46349B displayed moderate affinity for the 5-HT1C receptor and had no affinity for the other 5-HT1 subclass (5-HT1A, 5-HT1B or 5-HT1D), dopamine (D1 or D2), alpha adrenergic (alpha-1 or alpha-2), sodium and calcium channel and histamine (H1) receptors. It did not interact with histamine (H1), alpha-1 adrenergic and 5-HT3 receptors in smooth muscle preparations. No inhibition of the uptake of norepinephrine, ...
TY - JOUR. T1 - Management of arch hypoplasia after successful coarctation repair. AU - DeLeon, Maryann M.. AU - DeLeon, Serafin Y.. AU - Quinones, Jose A.. AU - Roughneen, Patrick. AU - Magliato, Kathy E.. AU - Vitullo, Dolores A.. AU - Cetta, Frank. AU - Bell, Timothy J.. AU - Fisher, Elizabeth A.. PY - 1997. Y1 - 1997. N2 - Background. Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a somewhat hypoplastic arch to grow or from clamp injury at the time of the initial repair, or from both causes. Because of mediastinal adhesions and minimal collateral circulation, use of extraanatomic bypass grafts appears to be the preferred approach. Methods. Six children or young adults presented with arch obstruction over a 3-year period. Their mean age was 13.5 ± 4 years, and the mean interval from the time of the initial repair was 10 ± 4 years. The mean age of the patients at the time of the initial repair was 3.2 ± 5 years. ...
Purpose of Review The purpose of this manuscript is to review the surgical techniques of aortic arch repair, imaging techniques for evaluating the pre- and post-operative aortic arch, and both normal...
Diseases of the cardiovascular system are predicted to be the leading worldwide cause of death by 2030.1,2 Cardiovascular diseases (CVDs) are characterised as diseases of lifestyle, associated with a Western diet and low levels of physical activity. However, ischaemic heart disease and other non-communicable diseases are likely to be major contributors to mortality in sub-Saharan Africa.2. Forms of these diseases (once associated with ageing3) are common in younger individuals; atherosclerotic lesions, aneurysms and strokes have been reported in children and young adults.4-6 Fatty dots and streaks, which may represent the early stages of atherosclerosis, have been found in the aortas of babies and infants.6. Risk factors in the increasing prevalence of CVD include cigarette smoking, high-fat diet, high cholesterol levels, obesity, diabetes, hypertension and HIV infection.1,4,7 Antiretroviral treatment for HIV-positive individuals also increases the risk of developing CVD.8. Certain ...
enlarged aorta - MedHelps enlarged aorta Center for Information, Symptoms, Resources, Treatments and Tools for enlarged aorta. Find enlarged aorta information, treatments for enlarged aorta and enlarged aorta symptoms.
The current study has demonstrated significant regional variation in access to treatment, the organization of clinical services, and mortality for patients with TAD in England. An analysis of HES data demonstrated that the variation in the proportion of TAD patients treated within 6 months of diagnosis ranged from 7.6% to 31.5% among counties and remained statistically significant after adjustment for potential confounders, including comorbidity, deprivation, disease severity, and population density. Regional variation was not associated with differences in mortality rates for patients that received treatment, but was associated with differences in mortality in those that did not receive treatment, implying that inequity in access to care has important effects on outcome. The analysis of NASCA data indicated wide regional variation in the volume and complexity of TAD cases undertaken in English cardiac centers. Centers undertaking higher volumes were more likely to treat more‐complex disease ...
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The speeds at which an aortic laceration can occur in an auto crash vary greatly. Doctors use the term Delta V when determining forces causing aortic tears.
O Somos faz parte de uma plataforma desenvolvida para facilitar o mapeamento das competências da FUNCAP, com o objetivo de incrementar a interação da Universidade em áreas de pesquisa científica e tecnológica com instituições públicas e privadas. A Plataforma Somos está em constante desenvolvimento pela Coordenadoria de Transferência e Inovação Tecnológica (CTIT).
Penyakit Aneurisma Aorta - Aneurisma aorta atau aneurisme aorta merupakan pembengkakan pembuluh aorta perut atau pembesaran aorta, pembuluh darah utama yang menyalurkan darah ke tubuh pada level abdomen. Baca Juga [more…] ...
noun the descending part of the aorta that branches into the thoracic and abdominal aortae • Hypernyms: ↑aorta * * * noun : the part of the aorta from the arch to its bifurcation that passes downward in the thoracic and abdominal cavities
In the early stages of fetal development, two aortic arches come from the heart, ascend upward and then descend behind the heart merging together to become a single aorta. As the heart develops normally, the right-sided arch disappears, leaving the left-sided arch to ascend upward and continue to the descending aorta behind the heart. The normally developed left-sided aorta lies in front of the trachea, or breathing tube, and esophagus, or swallowing tube.. A vascular ring is a defect where the arch vessels encircle the breathing and swallowing tubes.This is caused by abnormal development of the aortic arches. If both arches stay open it is called a double aortic arch. The two arches surround the breathing and swallowing tubes and may cause narrowing or compression of these structures and lead to breathing and/or feeding difficulties. In another form of a vascular ring, the left-sided arch disappears, and the right-sided arch stays open. If this is associated with an abnormal origin of the blood ...
Oxygenated blood begins its course down the chest through the thoracic aorta, a major blood vessel with branches that serve the chest muscles and lungs. This becomes the abdominal aorta.
Relaxation of Rat Aorta by Farrerol Correlates with Potency to Reduce Intracellular Calcium of VSMCs. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Researchers investigate the role of arterial stiffness in memory decline in older adults. A flexible aorta may be key to maintaining cognitive ability.
Study Flashcards On Ascending Aorta at Quickly memorize the terms, phrases and much more. makes it easy to get the grade you want!
article: A case of pediatric aortic coarctation: role of imaging - Journal of Radiological Review 2021 September;8(3):260-4 - Minerva Medica - Riviste
Learn more about Aortic Coarctation -- Adult at Grand Strand Medical Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at St. Davids HealthCare DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Aortic Coarctation -- Adult at TriStar Centennial Parthenon Pavilion DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
I was diagnosed in 2012 with ascending aorta dialation of 4.1 cm. In 2013 no change. Finally went back to dr in 2017 and echo showed 4.3 cm. 2 months later dr made me have a chest scan which read 4.5 cm. which is correct? Echo or scan? Dr wants […]
Source: Adapted from the National Institutes of Health. What does the term aorta mean? The term aorta refers to the large artery that carries blood from the heart to the rest of body. To find out more about this term, please search the news section of this website for related articles and information.. ...
Estudos morfológico e morfométrico do coração e da artéria aorta em ratos adultos desmamados precocemente / Morphological and morphometric studies of the heart and aorta artery in preciously weed adult rats
Survival Technology - SonoSims new aorta and IVC real-patient scanning cases are available in the Aorta/IVC Core Clinical Module
Differential effects on aortic segments could provide novel insights into the pathophysiology of increased arterial stiffness in CKD and potentially in various
Thoracic Aorta; page 732-737 Stephen J Thomas; Manual of Cardiac Anesthsia, William A dell, chapter 15, page 387-396, 1984 ... Fellows are trained to manage all type of thoracic surgeries which include video-assisted thoracoscopic surgery (VATS), open ... usually placed in the aorta or femoral artery, is used to return blood to the arterial circulation. The process of preparation ... thoracic aortic aneurysm repair, aortic dissection repair, heart transplants, lung transplants, heart/lung transplants, and ...
Grace, JB; Fox, IJ; Crowley, WP Jr; Wood, EH (November 1957). "Thoracic-aorta flow in man". J Appl Physiol. 11 (3): 405-418. ...
... and stroke as a primary causes of death and morbidity after thoracic aorta surgery. Patient's with a history of smoking and the ... "Surgery of the Thoracic Aorta". New England Journal of Medicine. 336 (26): 1876-1889. doi:10.1056/NEJM199706263362606. ISSN ... At the time of Safi's surgical training in the 70s and 80s, surgical treatment of thoracic aortic disease often led to an ... "Improved Prognosis of Thoracic Aortic Aneurysms: A Population-Based Study , Surgery , JAMA , JAMA Network". ...
The aorta, namely aortic aneurysms including thoracic aortic aneurysms and abdominal aortic aneurysms. The brain, including ... Compared to normal aortas, aneurysmal aortas have a much higher volume fraction of collagen and ground substance (54.8% vs. ... aortic aneurysms affecting the thoracic aorta, and abdominal aortic aneurysms. Aneurysms can arise in the heart itself ... A segment of the aorta that is found to be greater than 50% larger than that of a healthy individual of the same sex and age is ...
"Syphilitic aneurysm of the ascending aorta". Interactive Cardiovascular and Thoracic Surgery. 14 (2): 223-225. doi:10.1093/ ... SA begins as inflammation of the outermost layer of the blood vessel, including the blood vessels that supply the aorta itself ... September-October 2015). "Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology ... Syphilitic aortitis is inflammation of the aorta associated with the tertiary stage of syphilis infection. ...
"Chlorzoxazone inhibit contraction of rat thoracic aorta". Eur J Pharmacol. 545 (2-3): 161-6. doi:10.1016/j.ejphar.2006.06.063. ...
The thoracic aorta, viewed from the left side. (Pericardiacophrenic labeled at center left.) ... The pericardiacophrenic artery is a long slender branch of the internal thoracic artery. It accompanies the phrenic nerve, ... On their course through the thoracic cavity, the pericardiacophrenic arteries are located within and supply the fibrous ...
Owens, J. Cuthbert (1955-01-01). "Prolonged Experimental Occlusion of Thoracic Aorta During Hypothermia". Archives of Surgery. ... and their thoracic aortas were occluded for 2 hours, their kidneys showed no apparent damage when the dogs were rewarmed. This ...
March 2005). "Tracheal regeneration following tracheal replacement with an allogenic aorta". The Annals of Thoracic Surgery. 79 ... May 2003). "Long-term evaluation of the replacement of the trachea with an autologous aortic graft". The Annals of Thoracic ... May 2003). "Right ventricular cardiomyoplasty: 10-year follow-up". The Annals of Thoracic Surgery. 75 (5): 1464-8. doi:10.1016/ ... Chauvaud S, Carpentier A (June 2008). "Ebstein's anomaly: the Broussais approach". Multimedia Manual of Cardio-Thoracic Surgery ...
33 (6): 1385 -- Hypertension Nataf P, Lansac E (2006). "Dilation of the thoracic aorta: medical and surgical management". Heart ... of the aorta. The aorta has the highest compliance in the arterial system due in part to a relatively greater proportion of ... If the aorta becomes rigid because of disorders such as arteriosclerosis or atherosclerosis, the pulse pressure would be very ... high because the aorta becomes less compliant due to the formation of rigid lesions to the (otherwise flexible) aorta wall. ...
... the left in front of the descending thoracic aorta. Occasionally the three lobar veins on the right side remain separate, and ...
Aortic dissections can be further classified and treated depending on whether they involve the thoracic aorta, the abdominal ... is performed on the thoracic aorta. A ruptured aneurysm may be taken emergently for open, endovascular or combination repair. A ... The aorta is the largest artery in the body, and the major aortic branches continue to divide multiple times, giving way to ... It starts as a small plaque in the inner-most layer of the aorta called the intima, but the inflammatory process ulcerates and ...
Bernhard's work is documented in over 50 articles in the New England Journal of Medicine and the Journal of Thoracic and ... Greenwood, RD; AS Nadas; Rosenthal A. Freed; WF Bernhard (July 1977). "Ascending Aorta pulmonary artery anastromosis for ... During his career Bernhard also served as an attending surgeon thoracic cardiovascular surgery at the VA Hospital, West Roxbury ... He completed his medical training at Syracuse University Medical School, and after several thoracic and surgical residencies at ...
Rimmer L, Fok M, Bashir M (August 2014). "The History of Deep Hypothermic Circulatory Arrest in Thoracic Aortic Surgery". Aorta ... Rimmer L, Fok M, Bashir M (August 2014). "The History of Deep Hypothermic Circulatory Arrest in Thoracic Aortic Surgery". Aorta ... Rimmer L, Fok M, Bashir M (August 2014). "The History of Deep Hypothermic Circulatory Arrest in Thoracic Aortic Surgery". Aorta ... Rimmer L, Fok M, Bashir M (August 2014). "The History of Deep Hypothermic Circulatory Arrest in Thoracic Aortic Surgery". Aorta ...
... relaxes precontracted rat (thoracic) aorta and decreases blood pressure drastically. The decrease in blood ...
über Aneurysmen der Brustaorta (1864) - On aneurysms of the thoracic aorta. Pagel: Biographisches Lexikon (translated biography ...
In ILS, the arterial supply is usually derived from the lower thoracic or upper abdominal aorta. Venous drainage is usually to ... In general, the arterial supply of ELS comes from an aberrant vessel from thoracic aorta. It usually drains via the systemic ... Both types of sequestration usually have arterial supply from the thoracic or abdominal aorta. Rarely, the celiac axis, ... Pulmonary sequestrations usually get their blood supply from the thoracic aorta. (intrapulmonary sequestration drains via ...
... female patient's own aorta was grafted from the arch to the descending thoracic aorta and the left subclavian artery was ... in which the 16-year-old female patient's ascending aorta was grafted to the descending thoracic aorta. As of 1984, there had ... There is a gap between the ascending and descending thoracic aorta. In a sense it is the complete form of a coarctation of the ... in which the left subclavian artery was grafted into the descending thoracic aorta in a 14-year-old male patient. The first ...
The paravisceral and thoracic aorta are approached via a left-sided posteriolateral thoracotomy incision in approximately the ... De Bakey, M. E.; Cooley, D. A. (1953-06-20). "Successful resection of aneurysm of thoracic aorta and replacement by graft". ... If normal aorta exists superior to the iliac bifurcation, a tube graft can be sewn distally to that normal aorta. If the distal ... OAS is used to treat aneurysms of the abdominal and thoracic aorta, aortic dissection, acute aortic syndrome, and aortic ...
The physical diagnosis of diseases of the heart and thoracic aorta. 1876. "Arthur Ernest Sansom, M.D. Lond., F.R.C.P." Br. Med ...
Pseudoaneurysm of ascending aorta 35 years after repair of tetralogy of Fallot". Interactive Cardiovascular and Thoracic ... He has been a recognized trainer, too, with more than 100 cardio-thoracic surgeons around the world, trained under him. On the ... His first post graduate degree was the Master of Surgery (MS) which was followed by MCh in cardiovascular thoracic surgery, ... Annals of Thoracic Surgery. Archived from the original on 15 August 2014. Harpreet Wasir; Anil Bhan; Shiv Kumar Choudhary; ...
The autopsy revealed that Barrio's lungs and thoracic aorta had been pierced. Spanish Prime Minister Mariano Rajoy paid tribute ...
Schematic Illustration of Sympathetic Innervation The thoracic aorta, viewed from the left side. Scheme showing structure of a ... There are usually 22-23 pairs of these ganglia: 3 in the cervical region (cervical ganglia), 11 in the thoracic region (note ... Each ganglia within this chain is either cervical, thoracic, lumbar, or sacral. Preganglionic nerves from the spinal cord ... Throughout human evolution, the first thoracic and inferior cervical ganglia merged - and this resulting ganglion is called the ...
In rat thoracic aorta, the contractile activity is grouped as follows: ET-1 > SRTX-b > SRTX-a > SRTX-c at lower concentrations ...
... is a dilation of the proximal ascending aorta and aortic annulus. It may cause aortic regurgitation, ... thoracic aortic dissection, aneurysm and rupture. It is often associated with connective tissue diseases like Marfan syndrome ...
It is attached to the thoracic cavity by the diaphragm. Structures such as the aorta, inferior vena cava and esophagus pass ... In humans, the abdomen stretches from the thorax at the thoracic diaphragm to the pelvis at the pelvic brim. The pelvic brim ... The space above this inlet and under the thoracic diaphragm is termed the abdominal cavity. The boundary of the abdominal ... as well as their more familiar thoracic legs), which allow them to grip onto the edges of plant leaves as they walk around. In ...
Thoracic aortic aneurysms occur on the aorta as it passes through the chest cavity. These are less common than abdominal ... Infection in the aorta (vasculitis). In rare cases, abdominal aortic aneurysm may be caused by an infection or inflammation ... CT is used to watch the growth of a thoracic aortic aneurysm. Echocardiogram - This ultrasound exam is used to study the heart ... All types of abdominal aortic aneurysms occur in the part of the aorta that passes through the middle to low abdomen. ...
Wu, Tzu-Chi; Pai, Ching-Chou; Huang, Pin-Wen; Tung, Chun-Bin (11 November 2019). "Infected aneurysm of the thoracic aorta ... and CT imaging revealed a thoracic aortic aneurysm. He was successfully treated for the aneurysm with intravenous vancomycin, ...
The single right bronchial artery usually arises from one of the following: 1) the thoracic aorta at a common trunk with the ... The left bronchial arteries (superior and inferior) usually arise directly from the thoracic aorta. ... arch of the aorta, and the descending aorta." Histology image: 13903loa - Histology Learning System at Boston University ... Anatomy figure: 21:06-06 at Human Anatomy Online, SUNY Downstate Medical Center - "Branches of the ascending aorta, ...
The aorta, namely aortic aneurysms including thoracic aortic aneurysms and abdominal aortic aneurysms.[9] ... Compared to normal aortas, aneurysmal aortas have a much higher volume fraction of collagen and ground substance (54.8% vs. ... aortic aneurysms affecting the thoracic aorta, and abdominal aortic aneurysms. Aneurysms can arise in the heart itself ... "Interactive Cardiovascular and Thoracic Surgery. 14 (2): 223-25. doi:10.1093/icvts/ivr067. PMC 3279976. PMID 22159251.. ...
Talk:Anterior intercostal branches of internal thoracic artery. *Talk:Anterior intercostal veins ... Talk:Ascending aorta. *Talk:Ascending branch of medial circumflex femoral artery. *Talk:Ascending cervical artery ...
Thoracic aorta injury. *Cardiac tamponade. *GI *Blunt kidney trauma. *Ruptured spleen. *Neuro *Penetrating head injury ...
彈性動脈為管徑最大的動脈,通常離開心臟不遠,如主動脈、胸主動脈(thoracic aorta)、腹主動脈(abdominal aorta)、鎖骨
Thoracic aorta injury. *Biliary injury. *Chest injury. *Asphyxia. By activityEdit. *Reverse bite injury ...
"Journal of Thoracic Disease. 7 (8): 1311-1322. doi:10.3978/j.issn.2072-1439.2015.06.11. PMC 4561280. PMID 26380759.. ... Gaisl, Thomas; Bratton, Daniel J.; Kohler, Malcolm (2015-08-01). "The impact of obstructive sleep apnoea on the aorta". The ... "Proceedings of the American Thoracic Society. 5 (2): 173-8. doi:10.1513/pats.200708-119MG. PMC 2645251. PMID 18250209.. ... "Proceedings of the American Thoracic Society. 5 (2): 136-143. doi:10.1513/pats.200709-155MG. PMC 2645248. PMID 18250205.. ...
বক্ষপিঞ্জর (Thoracic cage). *উরঃফলক (Sternum). *পিঞ্জরাস্থি (Rib). *প্রগণ্ডাস্থি (Humerus). *কনুই (Elbow). *বহিঃপ্রকোষ্ঠাস্থি ( ... মহাধমনী (Aorta). *অলিন্দ (Atrium). *নিলয় (Ventricle). *হৃৎকপাটিকা (Heart valve). *রক্ত (Blood) ...
It passes beneath the aortic arch, crosses in front of the esophagus, the thoracic duct, and the descending aorta, and has the ... The carina of the trachea is located at the level of the sternal angle and the fifth thoracic vertebra (at rest). ... It enters the root of the left lung opposite the sixth thoracic vertebra. ... It enters the root of the right lung at approximately the fifth thoracic vertebra. The right main bronchus subdivides into ...
It passes through the posterior mediastinum in the thorax and enters the stomach through a hole in the thoracic diaphragm-the ... The celiac artery is the first major branch from the abdominal aorta, and is the only major artery that nourishes the digestive ... It is divided into cervical, thoracic and abdominal parts. The pharynx joins the esophagus at the esophageal inlet which is ... The muscular diaphragm separates the thoracic cavity from the abdominal cavity where most of the digestive organs are located. ...
... or for access to the thoracic aorta or the anterior spine (the latter may be necessary to access tumors in the spine). The ... Thoracic epidural analgesia or paravertebral blockade have shown to be the most effective methods for post-thoracotomy pain ... Treatment to aid pain relief for this condition includes intra-thoracic nerve blocks/opiates and epidurals, although results ... the first step used to facilitate thoracic surgeries including lobectomy or pneumonectomy for lung cancer or to gain thoracic ...
Thoracic aorta injury. *Cardiac tamponade. *GI *Blunt kidney trauma. *Ruptured spleen. *Neuro *Penetrating head injury ...
... aorta, or kidneys).[1] Hypertensive urgency is defined as having a systolic blood pressure over 180 mmHg or a diastolic blood ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Coronary artery aneurysm ...
The spine has cervical, thoracic, lumbar and caudal regions with the number of cervical (neck) vertebrae highly variable and ... unlike in the mammals where the left aortic arch forms this part of the aorta.[62] The postcava receives blood from the limbs ... especially flexible, but movement is reduced in the anterior thoracic vertebrae and absent in the later vertebrae.[63] The last ...
The arteries supplying the thymus are branches of the internal thoracic, and inferior thyroid arteries, with branches from the ... and extend outward and backward into the surrounding mesoderm and neural crest-derived mesenchyme in front of the ventral aorta ... The veins end in the left brachiocephalic vein, internal thoracic vein, and in the inferior thyroid veins. Lymphatic vessels ...
Malformed aorta, slow pulse, ischemia: these cause reduced blood flow to the renal arteries, with physiological responses as ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Aortic rupture ...
Thoracic aortaEdit. Main article: Descending thoracic aorta. The thoracic descending aorta gives rise to the intercostal and ... The aorta begins to descend in the thoracic cavity, and consequently is known as the thoracic aorta. After the aorta passes ... where the thoracic aorta (or thoracic portion of the aorta) runs from the heart to the diaphragm. The aorta then continues ... Descending aorta, thoracic part: Left bronchial arteries. esophageal arteries to the thoracic part of the esophagus. Third to ...
Injuries to the thoracic aorta and heart can also occur.[5] Minor complications include a subcutaneous hematoma or seroma, ... "Compact Digital Thoracic Drain Systems for the Management of Thoracic Surgical Patients: A Review of the Clinical Effectiveness ... "The Journal of Thoracic and Cardiovascular Surgery. 152 (2): 595-601.e4. doi:10.1016/j.jtcvs.2016.03.086. PMID 27210474.. ... A chest tube (chest drain, thoracic catheter, tube thoracostomy, or intercostal drain) is a flexible plastic tube that is ...
... and advancing an intravascular catheter through the aorta towards the vertebral arteries. At that point, radiocontrast is ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Coronary artery aneurysm ...
... in the 1950s and 1960s by thoracic surgeon and shock researcher R Adams Cowley, who founded what became the Shock Trauma Center ...
Coarctation of the aorta is also a known risk factor,[5] as is arteriovenous malformation.[7] Genetic conditions associated ... Thoracic aortic aneurysm. *Aneurysm of sinus of Valsalva. *Aortic dissection. *Coronary artery aneurysm ...
"Journal of Thoracic Disease. 8 (Suppl 2): S186-96. doi:10.3978/j.issn.2072-1439.2016.01.85. PMC 4775267. PMID 26981270.. ... These arteries join (anastamoses) with ascending branches of the bronchial arteries, which are direct branches from the aorta, ... and the carina is found at the level of the fourth thoracic vertebra (T4),[2] although its position may change with breathing.[ ...
Aorta. Sections. *Ascending aorta. *Aortic arch. *Descending aorta. *Thoracic aorta. *Abdominal aorta ... Left heart → Aorta → Arteries → Arterioles → Capillaries → Venules → Veins → Vena cava → (Right heart) ...
Thoracic aorta[edit]. This section needs expansion. You can help by adding to it. (October 2007) ... Abdominal aorta[edit]. inferior phrenic[edit]. celiac[edit]. *left gastric artery *hepatic branch ... left common carotid artery (directly from arch of aorta on left mostly)[edit]. internal carotid artery[edit]. *ophthalmic ... Left subclavian artery (directly from arch of aorta on left)[edit]. vertebral artery[edit]. *Meningeal branches of vertebral ...
The lower esophagus lies behind the heart and curves in front of the thoracic aorta. From the bifurcation of the trachea ... the parts of the esophagus in the thorax from the bronchial arteries and branches directly from the thoracic aorta, and the ... The thoracic duct, which drains the majority of the body's lymph, passes behind the esophagus, curving from lying behind the ... The esophagus is innervated by the vagus nerve and the cervical and thoracic sympathetic trunk.[5] The vagus nerve has a ...
Each thoracic segment supports one pair of legs. The meso- and metathoracic segments may each have a pair of wings, depending ... This dorsal blood vessel (element 14) is divided into two sections: the heart and aorta. The dorsal blood vessel circulates the ... The thoracic segments have one ganglion on each side, which are connected into a pair, one pair per segment. This arrangement ... Some insects, like the house fly Musca domestica, have all the body ganglia fused into a single large thoracic ganglion. ...
Both hearts are labeled with the following parts: 1. Ascending Aorta 2. Left Atrium 3. Left Ventricle 4. Right Ventricle 5. ... Passerines possess seven air sacs, as the clavicular air sacs may interconnect or be fused with the anterior thoracic sacs. ...
After the examination, the body has an open and empty thoracic cavity with chest flaps open on both sides, the top of the skull ... The heart can then be removed by cutting the inferior vena cava, the pulmonary veins, the aorta and pulmonary artery, and the ... Pathologist performing a human dissection of the abdominal and thoracic organs in an autopsy room. ...
"Dilation of the thoracic aorta: medical and surgical management". Heart. 92 (9): 1345-1352. doi:10.1136/hrt.2005.074781. ISSN ... The ascending aorta (AAo)[1] is a portion of the aorta commencing at the upper part of the base of the left ventricle, on a ... Porcelain aorta is extensive atherosclerotic calcification of the ascending aorta.[6] It makes aortic surgery difficult, ... The sinotubular junction is the point in the ascending aorta where the aortic sinuses end and the aorta becomes a tubular ...
Samet JM (May 2013). "Tobacco smoking: the leading cause of preventable disease worldwide". Thoracic Surgery Clinics. 23 (2): ... a condition in which a weak area of the abdominal aorta expands or bulges, and is the most common form of aortic aneurysm.[156] ...
"Annals of the American Thoracic Society. 18 (4): 613-622. doi:10.1513/AnnalsATS.202007-774OC. PMID 33064950.. ... Increased ratio of the diameter of the main pulmonary artery (pulmonary trunk) to the ascending aorta (measured at its ... American College of Chest Physicians; American Thoracic Society (September 2013), "Five Things Physicians and Patients Should ... American College of Chest Physicians; American Thoracic Society (September 2013), "Five Things Physicians and Patients Should ...
"Interactive Cardiovascular and Thoracic Surgery. 10 (6): 1026-1033. doi:10.1510/icvts.2009.229757. PMID 20308266.. CS1 maint: ... 1955: First heart valve allograft into descending aorta (Canada). *1963: First successful lung transplant by James D. Hardy ... "OPTN Policy 3.7 - Allocation of Thoracic Organs". United Network for Organ Sharing. 31 January 2013. Archived from the original ...
The close proximity of the esophagus to the thoracic aorta provides an excellent imaging opportunity. Transesophageal ... Thoracic aorta Aortic dissection Aortic aneurysm Atheromatous disease Plaque Blunt aortic trauma ... Maus T.M. (2016) Thoracic Aorta. In: Maus T., Nhieu S., Herway S. (eds) Essential Echocardiography. Springer, Cham. * First ... A thorough understanding of the use of TEE in evaluating the thoracic aorta including normal and pathologic presentations is ...
Tortuosity of the descending thoracic aorta is a condition in which the aorta is misshapen and is characterized by ... Tortuosity of the descending thoracic aorta is a condition in which the aorta is misshapen and is characterized by ... The descending thoracic aorta is one of four sections of the biggest heart artery called the aorta, notes WebMD. ... Tortuosity of the thoracic aorta is sometimes a sign of atherosclerotic disease, says a 2006 article in Angiology. ...
... are confined to the thoracic portion of the aorta including the ascending aorta, aorta arch, and the descending aorta. Of the ... Injury of the thoracic aorta refers to any injury which affects the portion of the aorta which lies within the chest cavity. ... If the injury is in the descending thoracic aorta this could lead to a hemothorax. Where as an injury to the ascending aorta ... Between the mobile ascending aorta and the relatively fixed descending thoracic aorta is the aortic isthmus. When there is a ...
The descending thoracic aorta is a part of the aorta located in the thorax. It is the third and last part of the thoracic aorta ... The descending thoracic aorta is a continuation of the descending aorta and becomes the abdominal aorta when it passes through ... The descending thoracic aorta begins at the lower border of the fourth thoracic vertebra and ends in front of the lower border ... The descending thoracic aorta is part of the aorta, which has different parts named according to their structure or location. ...
Descending Thoracic Aorta. Perioperative Care After Thoracoabdominal Aortic Aneurysm Repair: The Baylor College of Medicine ... Society for Vascular Surgery (SVS) and Society of Thoracic Surgeons (STS) Reporting Standards for Type B Aortic Dissections ... Genes Associated With Thoracic Aortic Aneurysm and Dissection: 2019 Update and Clinical Implications ... In this consensus statement, a new anatomic classfication system is proposed for thoracic aortic dissections. The acuity of ...
Definition of esophageal branches of the thoracic aorta. Provided by Stedmans medical dictionary and Includes ... esophageal branches of the thoracic aorta. Definition: branches arising directly from the anterior aspect of the portion of the ... thoracic aorta adjacent to the esophagus, by which most of the thoracic part of the esophagus is supplied. ...
The aorta has five separate segments. The descending aorta begins at the arch of the aorta (where it loops over the heart to ... The aorta originates from the left ventricle of the heart. It ends in the abdomen where it branches into the two common iliac ... the thoracic and the abdominal. The descending aorta (thoracic aorta) is between the arch of the aorta and the diaphragm muscle ... The right branches are longer than the left, because the descending aorta (thoracic aorta) is on the left side of the vertebrae ...
Thoracic Aorta Repair: Volume and Type. 2019, N = 205. Cleveland Clinic surgeons performed 205 descending thoracic aorta/ ... Thoracic Aorta Repair: In-Hospital Mortality. 2019. Extensive experience with both open and endovascular treatment options for ... Home / Institutes & Departments / Heart, Vascular & Thoracic Institute (Miller Family) / Heart, Vascular & Thoracic Institute ( ... Previous: Aortic Arch Aneurysm Repairs Next: Thoracic Endovascular Repair First for Extensive Aortic Disease: The Staged Hybrid ...
Aorta Thoracic; Traumatic Rupture Intervention ICMJE Device: Valiant™ endoluminal procedure Thoracic endovascular aortic repair ... Endovascular Repair for the Descending Thoracic Aorta (ERRATA). The safety and scientific validity of this study is the ... Endovascular Repair for the Descending Thoracic Aorta Official Title ICMJE Endovascular Repair for Acute Traumatic Transection ... of the Descending Thoracic Aorta Brief Summary Most blunt aortic injuries occur in the proximal proximal descending aorta ...
Medtronic received FDA approval to offer its Valiant Captivia Thoracic Stent Graft System as a treatment option for type B ... Valiant Captivia Thoracic Aorta Stent Receives New Approval. January 28th, 2014 Medgadget Editors Cardiac Surgery, Cardiology, ... The system previously had FDA indication for treatment of aneurysms and penetrating ulcers of the descending thoracic aorta. ... Product page: Valiant Thoracic Stent Graft With the Captivia Delivery System…. Press release: Valiant Captivia Thoracic Stent ...
Temporary hyperglycaemia provokes monocyte adhesion to endothelial cells in rat thoracic aorta.. Otsuka A1, Azuma K, Iesaki T, ... an en face method for observation of endothelial surface after immunohistochemical staining for CD68 in the thoracic aortas of ...
Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta.. J P Cooke, N A Andon, X J Girerd, A T ... Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta.. J P Cooke, N A Andon, X J Girerd, A T ... Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta.. J P Cooke, N A Andon, X J Girerd, A T ... Subsequently, animals were killed, thoracic aortas were harvested, and vascular rings were studied in vitro. Rings were ...
In this article, we describe the potential of helical CT using dual-slice technology to evaluate thoracic aortic diseases such ... the capability of noninvasive imaging of the thoracic aorta has been enhanced considerably. ... Aorta, Thoracic / radiography*. Aortic Aneurysm, Thoracic / radiography. Aortic Diseases / diagnosis*. Diverticulum / ... With the advent of helical CT, the capability of noninvasive imaging of the thoracic aorta has been enhanced considerably. In ...
Fluorescence emission intensity from a culture of embryonic rat thoracic aorta medial layer (A-10 line) myoblast cells that ... Rat Thoracic Aorta Myoblast Cell Actin. YFP Bandpass Emission (Narrow Bandwidth Excitation) Blue-Green Set. Fluorescence ... emission intensity from a culture of embryonic rat thoracic aorta medial layer (A-10 line) myoblast cells that were transfected ...
... emission intensity observed with the Nikon YFP HYQ blue-green excitation filter combination in a culture of rat thoracic aorta ... Rat Thoracic Aorta Myoblast Cell Mitochondria. YFP Bandpass Emission (Narrow Bandwidth Excitation) Blue-Green Set. Fluorescence ... emission intensity from a culture of rat thoracic aorta myoblast (A-10 line) cells that were transfected with a pEYFP- ...
Thoracic Aorta Injury - Classification. Classification. There are inconsistencies in the terminology of aortic injury. There ... the latter is used when a tear occurs across all or nearly all of the circumference of the aorta. Rupture is defined as a ... the term accurately gauges the severity of tears in the aorta. A rupture can be either complete or partial, and can be ... are several terms which are interchangeably used to describe injury to the aorta such as tear, laceration, transection, and ...
Is there anyone out there living with an ascending thoracic aorta aneurysm? I just found out I have one that is 4.5 cm. They ... Ascending Thoracic Aorta Aneurysm, Part 1 of 2 - CLOSED. Chronic Illness Forums. , ... I just discovered that my grandma has ascending thoracic aorta with maxiaml transerve dimsnesion of 4.3cm. She is 75 years old ... It was "suggested" I see a surgeon, heck, I searched for the top thoracic surgeons in NYC, and emailed him after no sleep the ...
In the present case, the patient underwent thoracic aorta replacement 30 years ago when he was under-aged. That is, his aorta ... Home , March 05, 2015 - Volume 128 - Issue 5 , Anastomotic Pseudoaneurysm at 30 Years after Thoracic Aorta... ... Anastomotic Pseudoaneurysm at 30 Years after Thoracic Aorta Surgery. Ren, Chang-Wei; Huang, Lian-Jun; Lai, Yong-Qiang; Sun, Li- ... He had a history of thoracic aorta replacement, which was performed 30 years ago because of a coarctation of the descending ...
How is a thoracic aortic aneurysm diagnosed?. Early diagnosis of a thoracic aneurysm is critical to managing the condition. The ... Diagnosing a thoracic aneurysm is difficult because often there are no symptoms, and often the condition goes undiagnosed until ... The risk of rupture increases when the aneurysm is larger than about twice the normal diameter of a healthy aorta blood vessel. ... Heart, Vascular & Thoracic Institute (Miller Family). The latest information about heart & vascular disorders, treatments, ...
... Gui-Hua Yue,1 Shao-Yuan ... "Effect of Huanglian Jiedu Decoction on Thoracic Aorta Gene Expression in Spontaneous Hypertensive Rats," Evidence-Based ...
Is there anyone out there living with an ascending thoracic aorta aneurysm? I just found out I have one that is 4.5 cm. They ... LOL! Well, what I mean is my ascending thoracic aorta aneurysm 5.3 cm per the CT SCAN. I go for my first consult with the heart ... I had a ct-scan as a follow up to a echo and an ascending thoracic aorta aneurysm was found. It measured 4.7 cm...had another ... He even has a specialty in the field - ascending thoracic aorta aneurysm - go figure!! I guess Ill be in good hands. Initially ...
thoracic aorta. Dilation of the ascending aorta entails a high risk of dissection or aortic rupture in the absence of surgical ... Aortic aneurysms remain the 13th leading cause of mortality in western countries.1,2 The incidence of thoracic aortic aneurysms ... Overall, it represents 50% of all thoracic aneurysms, but can be separated into two distinct entities, according to aetiology ...
This mode of acquisition provided images of the thoracic aorta free of motion artefact. The chronic dissection flap could ... Aortic motion artefact is the most common cause of false positive detection of dissection of the ascending aorta. Motion ... and progressing distally to the descending aorta (panel C, three dimensional reconstruction in sagittal section). Advanced post ... clearly be seen arising in the proximal, aneurysmal ascending aorta (panel A, axial CT section), extending to the head and neck ...
Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride. The safety and scientific validity of this study ... Aortic Aneurysm, Thoracic. Vascular Diseases. Cardiovascular Diseases. Signs and Symptoms, Respiratory. Signs and Symptoms. ... Genetics Home Reference related topics: Familial thoracic aortic aneurysm and dissection MedlinePlus related topics: Aneurysms ...
The thorax was opened to expose the aorta, and the descending thoracic aorta from the heart to diaphragm was dissected free. ... Effect of Cymbopogon citratus and Citral on Vascular Smooth Muscle of the Isolated Thoracic Rat Aorta. R. Chitra Devi,1 S. M. ... L. H. Fang, Y. M. Mu, L. L. Lin, P. G. Xiao, and G. H. Du, "Vasorelaxant effect of euxanthone in the rat thoracic aorta," ... The rats were killed by cervical dislocation, and the thoracic aorta was isolated according to the procedure of Jain [18] with ...
Aorta, thoracic explanation free. What is Aorta, thoracic? Meaning of Aorta, thoracic medical term. What does Aorta, thoracic ... Looking for online definition of Aorta, thoracic in the Medical Dictionary? ... Synonym(s): aorta thoracica, pars thoracica aortae, thoracic part of aorta. aorta. pl. aortae, aortas [L.] the great artery ... Related to Aorta, thoracic: ascending aorta, abdominal aorta, Internal thoracic artery, Thoracic aortic aneurysm tho·rac·ic a· ...
ICD-10-PCS code 02NW3ZZ for Release Thoracic Aorta, Descending, Percutaneous Approach is a medical classification as listed by ...
The NO-cGMP pathway may be involved in the relaxation of DL0805 in endothelium-intact aorta. The vasorelaxant effect of DL0805 ... The Vasorelaxant Mechanisms of a Rho Kinase Inhibitor DL0805 in Rat Thoracic Aorta. Lili Gong 1,2. ... "The Vasorelaxant Mechanisms of a Rho Kinase Inhibitor DL0805 in Rat Thoracic Aorta." Molecules 17, no. 5: 5935-5944. ... Keywords: DL0805; vasorelaxation; Rho kinase; aorta; endothelium; nitric oxide DL0805; vasorelaxation; Rho kinase; aorta; ...
SUNY Figs 21:06-00 - "Branches of the ascending aorta, arch of the aorta, and the descending aorta." ... thoracic aorta. visceral: bronchial - esophageal - mediastinal parietal: posterior intercostal 3-11 - subcostal - superior ... internal thoracic: anterior intercostal - thymic - pericardiacophrenic - terminal (musculophrenic, superior epigastric). ... The esophageal arteries four or five in number, arise from the front of the aorta, and pass obliquely downward to the esophagus ...
... The thoracic aortae from both groups were used for electron microscopy and immunocytochemistry for big endothelin (ET)-1, ET-1 ... and elevated concentrations of ET-1 in the blood plasma as well as in homogenized thoracic aortae were observed in the cadmium- ... and the blood plasma and homogenized thoracic aortae were prepared for assays of big ET-1 and ET-1 concentrations. A remarkable ...
  • Interesting retrospective imaging study of true and false lumens with or without bare metal stents placed distally in the abdominal aorta. (
  • It is divided into two segments, the thoracic and the abdominal. (
  • The descending thoracic aorta begins at the lower border of the fourth thoracic vertebra and ends in front of the lower border of the twelfth thoracic vertebra, at the aortic hiatus in the diaphragm where it becomes the abdominal aorta. (
  • The descending thoracic aorta is a continuation of the descending aorta and becomes the abdominal aorta when it passes through the diaphragm. (
  • Compare abdominal aorta . (
  • What is ectatic abdominal aorta? (
  • Abdominal aorta calcification means what? (
  • We show that in aged apoE(-/-) mice, medial smooth muscle cells (SMCs) beneath intimal plaques in abdominal aortae become activated through lymphotoxin beta receptor (LTbetaR) to express the lymphorganogenic chemokines CXCL13 and CCL21. (
  • Thoracic and abdominal aorta media of aged apoE−/− aorta is infiltrated by leukocytes and shows differential loss of integrity. (
  • b) Elastin staining of ATLO-free diseased abdominal aorta shows loss of elastic fiber integrity in the inner media (left arrows), whereas ATLO-associated abdominal aorta shows loss of integrity in inner and outer media (right arrows). (
  • Finally, we wondered whether ATLO formation affected the integrity of the aorta, as it has been suggested in humans where B cells within the adventitia of abdominal aortae characterize specimens with aneurysm (42-44). (
  • Indeed, ATLOs were associated with leukocyte infiltration, including CD68+ cells, of the abdominal aorta in both the outer and inner media layers (Fig. 9 a, left). (
  • 2 CT studies reveal aortic thickening (presumed aortitis) in 45-65% of patients with GCA at diagnosis, 3 , 4 and an ultrasound study revealed abnormality of the abdominal aorta in 90% of patients with GCA at diagnosis. (
  • Magnetic Resonance Imaging of the Thoracic Aorta: A Review of Technical and Clinical Aspects, Including Its Use in the Evaluation of Aneurysms and Acute Vascular Conditions, Diagnosis and Treatment of Abdominal and Thoracic Aortic Aneurysms Including the Ascending Aorta and the Aortic Arch, Reinhart T. Grundmann, IntechOpen, DOI: 10.5772/21835. (
  • Diagnosis and Treatment of Abdominal and Thoracic Aortic Aneurysms Including the Ascending. (
  • Mycotic aneurysm of the abdominal aorta in a patient undergoing hemodialysis: an unusual complication of Staphylococcus aureus bacteremia. (
  • Roberto Chiesa (Milan, Italy) invites you to the CX 2020 LIVE Aortic Podium 1st Session which will feature abdominal aortic and thoracic aortic presentations and discussion from specialists in the field, including Tilo Kölbel, Frank Arko, Eric Verhoeven, Stephan Haulon, Giovanni Torsello and Fabio Verzini. (
  • High-pitch dual-source CT angiography of the thoracic and abdominal aorta: is simultaneous coronary artery assessment possible? (
  • b) abdominal aorta, including diaphragmatic aorta and aorta at the level of renal arteries origin (levels 4 and 5 of quantitative analysis). (
  • Measurement of oxygen uptake by thoracic and abdominal segments of rat aorta showed significantly lower rates in the abdominal than in the thoracic aorta of adult animals. (
  • The evidence suggests that as a rat ages the respiratory rate of abdominal aorta falls more sharply than that of the thoracic segment. (
  • This result may provide an explanation for the relatively high incidence of atherosclerosis in abdominal aorta. (
  • Shiga T, Wajima Z, Apfel CC, Inoue T, Ohe Y. Diagnostic accuracy of transesophageal echocardiography, helical computed tomography, and magnetic resonance imaging for suspected thoracic aortic dissection: systematic review and meta-analysis. (
  • From April 2002 to November 2014, patients referred to our Department with a diagnosis of acute transection of thoracic aorta will be studied by preoperative Computed Tomography (CT) evaluation in order to perform thoracic endovascular aortic repair (TEVAR) with left subclavian artery coverage. (
  • Computed tomography of the chest shows that right-sided unilateral thoracic osteophytosis is a common phenomenon. (
  • Nongated axial chest computed tomography (CT), traditionally used to evaluate aortic size, does not account for the obliquity, systolic expansion, and nonaxial motion of the aorta during the cardiac cycle. (
  • Acute hemopericardium was diagnosed preoperatively by computed tomography in three patients with acute dissection of the thoracic aorta. (
  • SETTING & PARTICIPANTS: The Agatston score of coronary arteries and thoracic aorta was measured by 16-slice spiral computed tomography in 281 KTRs. (
  • BACKGROUND: Thoracic aortic aneurysm is one of the most common aorta pathologies worldwide, which is commonly evaluated by computed tomography angiography (CTA). (
  • An infected aneurysm of the thoracic aorta is a rare clinical condition with significant morbidity and mortality. (
  • Moreno-Cabral CE, Miller DC, Mitchell RS, Stinson EB, Oyer PE, Jamieson SW, Shumway NE (1984) Degenerative atherosclerotic aneurysms of the thoracic aorta: Determinants of early and late surgical outcome. (
  • Endovascular treatment of synchronous and metachronous aneurysms of the thoracic aorta. (
  • Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta. (
  • CONCLUSIONS We conclude that the endothelium-dependent relaxation is normalized in hypercholesterolemic rabbit thoracic aorta by in vivo exposure to L-arginine, the precursor for EDRF. (
  • Transport of 125I-albumin across normal and deendothelialized rabbit thoracic aorta in vivo. (
  • ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease. (
  • Extensive experience with both open and endovascular treatment options for patients with thoracic aortic disease results in life-saving therapy for patients. (
  • We sought to establish the contribution of unwarranted variation in care to regional differences in outcomes observed in patients with thoracic aortic disease in England. (
  • Conclusions Changes in the organization of services that address unwarranted variation in the provision of care for patients with thoracic aortic disease in England may result in more‐equitable access to treatment and improved outcomes. (
  • Impact of beta-blockade premedication on image quality of ECG-gated thoracic aorta CT angiography. (
  • OBJECTIVE: The purpose of this study was to prospectively evaluate the average heart rate and heart rate variability required for diagnostic imaging of the coronary arteries with high-pitch dual-source CT angiography of the thoracic and thoracoabdominal aorta. (
  • mean age, 68 +/- 13 years) underwent clinically indicated CT angiography of the thoracic (n = 33) and thoracoabdominal (n = 67) aorta with a dual-source 128-MDCT scanner in ECG-synchronized high-pitch (pitch, 3.2) data acquisition mode. (
  • Effective radiation doses were 2.3 +/- 0.3 mSv for thoracic and 4.4 +/- 0.5 mSv for thoracoabdominal CT angiography. (
  • The average scan times were 0.88 +/- 0.06 second for thoracic and 1.67 +/- 0.15 seconds for thoracoabdominal CT angiography. (
  • CONCLUSION: For patients with an average heart rate less than 63 beats/min and heart rate variability less than 1.2 beats/min, dual-source CT angiography of the thoracoabdominal aorta at a high pitch of 3.2 delivers diagnostic depiction of the coronary arteries at a low radiation dose. (
  • Subjects underwent MR angiography to image and reconstruct three-dimensional (3D) geometric models of the thoracic aorta. (
  • To investigate the effects of prospective cardiac gating and low kilovoltage parameters on image quality and radiation dose when acquiring CT angiography of the thoracic aorta (CTTA). (
  • The system previously had FDA indication for treatment of aneurysms and penetrating ulcers of the descending thoracic aorta. (
  • Transluminal placement of endovascular stent-grafts for treatment of penetrating ulcers of the descending thoracic aorta appears to be a possible alternative to classical surgery. (
  • However, a different mechanism is involved when the ascending aorta proximal to the isthmus is torn. (
  • Most blunt aortic injuries occur in the proximal proximal descending aorta causing acute transection of this vessel. (
  • The chronic dissection flap could clearly be seen arising in the proximal, aneurysmal ascending aorta (panel A, axial CT section), extending to the head and neck vessels (panel B, sagittal CT section), and progressing distally to the descending aorta (panel C, three dimensional reconstruction in sagittal section). (
  • However, complications developing around the site proximal to the occlusion by resuscitative endovascular balloon occlusion of the aorta have almost never been studied. (
  • resuscitative endovascular balloon occlusion of the aorta may have been the cause of the increased bleeding of the thoracic injury at the proximal site of the aorta occlusion. (
  • It is necessary to note that the use of resuscitative endovascular balloon occlusion of the aorta may increase bleeding in sites proximal to occlusions, even in the case of minor injuries without active bleeding at the initial diagnosis. (
  • MDCT measurements of the thoracic aorta should use ECG-gated double-oblique short-axis images for accurate quantification. (
  • Cardiac gating leads to less artifacts and more accurate measurements of the thoracic aorta and root. (
  • Without gating the aortic root and ascending aorta are particularly prone to artifact. (
  • Although echocardiographic criteria exist to detect aortic root dilation, comparably standardized methods have not been developed to detect enlargement of the remainder of the thoracic aorta. (
  • MATERIAL AND METHODS: In this retrospective study, ECG-gated thoracic aorta CTA images of 40 patients without beta-blocker administration were compared with ECG-gated images of 40 patients with beta-blockade. (
  • Temporary hyperglycaemia provokes monocyte adhesion to endothelial cells in rat thoracic aorta. (
  • Monocyte adhesion to endothelial cells in vivo was quantitated using an en face method for observation of endothelial surface after immunohistochemical staining for CD68 in the thoracic aortas of Sprague-Dawley rats after several kinds of blood glucose rises. (
  • Curcumin Attenuates High Glucose-Induced Inflammatory Injury through ROS-PI3K/AKT-NF-κB Signaling Pathway in Rat Thoracic Aorta Endothelial Cells. (
  • The aim of the present study is to investigate the inflammatory effect of high glucose and the anti-inflammatory effect of CUR induced by high glucose in rat thoracic aorta endothelial cells (TAECs). (
  • Tortuosity of the descending thoracic aorta is a condition in which the aorta is misshapen and is characterized by abnormalities in blood vessels, particularly in arteries, says Genetics Home Reference. (
  • In descending order, these include the Bronchial arteries Mediastinal arteries Esophageal arteries Pericardial arteries Superior phrenic arteries Note: The posterior intercostal arteries are branches that originate throughout the length of the posterior aspect of the descending thoracic aorta. (
  • The esophageal arteries four or five in number, arise from the front of the aorta , and pass obliquely downward to the esophagus , forming a chain of anastomoses along that tube, anastomosing with the esophageal branches of the inferior thyroid arteries above, and with ascending branches from the left inferior phrenic and left gastric arteries below. (
  • The case of a 25-year-old woman with coarctation of the thoracic aorta and combined bilateral fibromuscular dysplasia of the renal arteries is reported. (
  • A balloon catheter has been described which can be inserted into the aorta from one of the brachiocephalie arteries. (
  • Medin derived from lactadherin expressed by smooth muscle cells aggregates into amyloid in certain arteries, particularly the thoracic aortic media layer, and may have a role in the generation of the potentially lethal conditions of thoracic aortic aneurysm and dissection. (
  • The courses are based on practical dissection of 5-7 cadavers (legs, arms thoracic aorta and supraaortic arteries) under the guidance of expert tutors. (
  • This procedure is sometimes called thoracic EVAR, or TEVAR. (
  • In a retrospective analysis, all the patients submitted to thoracic endovascular aneurysm repair (TEVAR) between March 2009 and February 2015, were identified. (
  • Purpose: To determine the efficacy of thoracic endovascular aortic repair (TEVAR) for degenerative aneurysm involving only the descending thoracic aorta (DTAA). (
  • Thoracic endovascular aortic repair (TEVAR) has emerged as a viable alterative to conventional open repair for the treatment of these injuries. (
  • An emergency thoracic endovascular aortic repair (TEVAR) for the thoracic aortic aneurysm was performed. (
  • The close proximity of the esophagus to the thoracic aorta provides an excellent imaging opportunity. (
  • This malformation of the aorta sometimes also displaces the esophagus and causes chest pain. (
  • branches arising directly from the anterior aspect of the portion of the thoracic aorta adjacent to the esophagus, by which most of the thoracic part of the esophagus is supplied. (
  • In front of the descending thoracic aorta lies the root of the left lung, the pericardium, the esophagus, and the diaphragm. (
  • The esophagus, which is covered by a nerve plexus lies to the right of the descending thoracic aorta. (
  • Lower, the esophagus passes in front of the aorta, and ultimately is situated on the left. (
  • There are several terms which are interchangeably used to describe injury to the aorta such as tear, laceration, transection, and rupture. (
  • Acute traumatic thoracic aortic transection is a devastating injury that often occurs in the context of multiple associated traumatic injuries. (
  • A traumatic injury to the thoracic aorta can cause disruption of any of these parts. (
  • Karmy-Jones R, Ferrigno L, Teso D, Long WB 3rd, Shackford S. Endovascular repair compared with operative repair of traumatic rupture of the thoracic aorta: a nonsystematic review and a plea for trauma-specific reporting guidelines. (
  • This review highlights some of the anatomic and technical considerations regarding endovascular repair of traumatic thoracic aortic injuries, and reviews reported outcomes. (
  • Angiographic description of blunt traumatic injuries to the thoracic aorta with specific relevance to endograft repair. (
  • Calcification of blood vessel walls (including of the aorta) is commonly detected by X-ray, CT scan , or ultrasound tests. (
  • However the predictive value of thoracic aorta calcification (TAC) that can be additionally identified without further scanning during assessment of CAC is unknown. (
  • however, calcification of the thoracic aorta was detected on admission. (
  • We assessed the evolution of coronary artery (CAC) and thoracic aorta calcification and their determinants in a cohort of prevalent KTRs. (
  • CAC and aorta calcification scores increased significantly (by a median of 11% and 4% per year, respectively) during follow-up. (
  • Independent determinants of aorta calcification progression were higher baseline aorta calcification score, higher pulse pressure, use of a statin, older age, higher serum phosphate level, use of aspirin, and male sex. (
  • Significant regression of CAC or aorta calcification was not observed in this cohort. (
  • Cleveland Clinic surgeons performed 205 descending thoracic aorta/thoracoabdominal aorta repair procedures in 2019. (
  • In the current reporting year, Cleveland Clinic surgeons performed 127 elective and and 39 emergency descending thoracic/thoracoabdominal endovascular aortic procedures. (
  • It was "suggested" I see a surgeon, heck, I searched for the top thoracic surgeons in NYC, and emailed him after no sleep the entire night. (
  • Surgeons can also repair or remodel nearby sections of the aorta that appear to be in danger. (
  • Penetrating aortic ulcers and intramural hematomas of the thoracic aorta are potentially dangerous and treated aggressively by Temple cardiovascular and vascular surgeons usually by an endovascular procedure. (
  • Do thoracic surgeons operate on splenic artery aneurysms? (
  • There, the Bluhm Cardiovascular Institute surgeons that operate on the thoracic aorta were able to repair the ruptured aorta by placing a stent-graft tube into the thoracic aorta, where it acts as a "cast" that lines the aorta from the inside. (
  • The thoracic course is designated for Advanced Vascular Surgeons. (
  • This mode of acquisition provided images of the thoracic aorta free of motion artefact. (
  • High-resolution images of the thoracic aortic wall were obtained by TEMRI in 22 subjects (8 normals, 14 with aortic atherosclerosis). (
  • The risk of rupture increases when the aneurysm is larger than about twice the normal diameter of a healthy aorta blood vessel. (
  • The body's largest blood vessel, the aorta carries the blood pumped from the heart to the rest of the body. (
  • The two most common aortic conditions are aneurysm (a weak area in the wall of the aorta that bulges outwards) and dissection (a tear in the inner lining of the aorta that allows blood in between the layers of the blood vessel). (
  • Computational analysis techniques are continually being improved in an attempt to better recreate physiologic blood flow patterns in the thoracic aorta where indices of wall shear stress (WSS, defined as the tangential force per unit area exerted on a blood vessel wall as a result of flowing blood) have correlated with intimal thickening [ 20 - 23 ]. (
  • The descending thoracic aorta is one of four sections of the biggest heart artery called the aorta, notes WebMD. (
  • The aorta then arches back over the right pulmonary artery. (
  • The aorta is an artery that conveys oxygenated blood from the heart to other parts of the body. (
  • pl. aortae, aortas [L.] the great artery arising from the left ventricle, being the main trunk from which the systemic arterial system proceeds. (
  • The aorta is the largest artery in the body, leaving directly from the left ventricle of the heart to supply blood to the entire body. (
  • Griepp RB, Ergin KA, Galla JD, Lansman S, Khan N, Quintana C, McCollough J, Bodian C (1996) Looking for the artery of Adamkiewicz: A quest to minimize paraplegia after operations for aneurysms of the descending thoracic and thoracoabdominal aorta. (
  • Stanford Type B lesions involve the thoracic aorta distal to the left subclavian artery. (
  • AIM: The aim of this paper was to compare hospital outcomes in patients undergoing elective surgery of the thoracic aorta using the right axillary artery (RAA) and the innominate artery (IA) as a cannulation site for cardiopulmonary bypass (CPB) arterial inflow. (
  • Most common location is distal to the L subclavian artery, probably because the mobile aortic arch is continuous with the immobile descending thoracic aorta at this point (shear stress). (
  • PA and lateral chest radiographs: Large, circumscribed anterior mediastinal mass abutting the ascending aorta, pulmonary artery, and left heart border. (
  • The term Acute Aortic Syndrome (AAS) is used to describe three closely related emergency entities of the thoracic aorta: classic Aortic Dissection (AD), Intramural Hematoma (IMH) and Penetrating Atherosclerotic Ulcer (PAU). (
  • The descending aorta begins at the arch of the aorta (where it loops over the heart to begin its descent). (
  • The descending aorta (thoracic aorta) is between the arch of the aorta and the diaphragm muscle below the ribs. (
  • The right branches are longer than the left, because the descending aorta (thoracic aorta) is on the left side of the vertebrae. (
  • He had a history of thoracic aorta replacement, which was performed 30 years ago because of a coarctation of the descending aorta. (
  • The part of the descending aorta that extends from the arch of the aorta to the diaphragm. (
  • the large upper part of the ascending arch and descending aorta, supplying many parts of the body, such as the heart, ribs, chest muscles, and stomach. (
  • The part of the descending aorta that supplies structures as far down as the diaphragm. (
  • SUNY Figs 21:06-00 - "Branches of the ascending aorta , arch of the aorta , and the descending aorta . (
  • For example, the patient might have surgery to repair an aneurysm in the ascending aorta, then an endovascular stent to strengthen the descending aorta. (
  • Kazerooni EA, Bree RL, Williams DM (1992) Penetrating atherosclerotic ulcers of the descending aorta: Evaluation with CT and distinction from aortic dissection. (
  • Stanford Type A lesions involve the ascending aorta and aortic arch and may or may not involve the descending aorta. (
  • The Stanford classification has replaced the DeBakey classification (type I= ascending, arch and descending aorta: type II= only ascending aorta: type III= only descending aorta). (
  • Recently, surface-coil magnetic resonance imaging (MRI) has been proposed for atherosclerotic plaque imaging in the descending aorta (6) . (
  • CT revealed a thoracic aneurysm, which turned out to be caused by MRSA bacteremia. (
  • All patients with a thoracic aortic injury need to be treated either surgically with endovascular repair or open surgical repair or with medicine to keep their blood pressure and heart rate in the appropriate range. (
  • Dilation of the ascending aorta entails a high risk of dissection or aortic rupture in the absence of surgical treatment. (
  • The aim of this study was to present and assess the quality of a new tool for the semi-automatic quantification of thoracic aorta dilation dimensions. (
  • Vascular effects of crude extract of dried and powdered calyces of Hibiscus sabdariffa were evaluated on isolated thoracic aorta of male Wistar rats on organ chambers. (
  • The present study was undertaken to investigate the effect of CAPE on isolated thoracic aorta of menopausal model rats. (
  • The effects of chronic AC magnetic field on contraction and relaxation of isolated thoracic aorta rings of healthy and diabetic rats. (
  • The effects of a chronic exposure of healthy and diabetic rats to a 50 Hz magnetic field on vasoconstriction and vasodilation of isolated thoracic aorta rings should be investigated. (
  • After exposure , all rats were killed and the thoracic aorta was isolated. (
  • Wistar rats' thoracic aortas were cut into 3-mm-thick rings, which were stretched using a pair of hooks in an organ bath (Krebs-Henseleit solution, 37°C, pH=7.4). (
  • Postnatal overnutrition affects metabolic and vascular function reflected by physiological and histological changes in the aorta of adult Wistar rats. (
  • Just found out in the last two weeks that I have an ascending thoracic aneurysm. (
  • Fat deposits from obesity sometimes elevate the diaphragm, which then pushes on the aorta. (
  • Presented by Dr. Bavaria yesterday at the 2014 annual meeting of the Society for Thoracic Surgery, 12-month data from the 50 patients evaluated in Dissection demonstrate safety and efficacy of the Valiant Captivia System in the treatment of dissections, with excellent technical success. (
  • To the Editor: We report a strategy for an asymptomatic anastomotic pseudoaneurysm that occurred 30 years after aorta surgery. (
  • It is a lot less risk and everything I've read has attached something along the phrase of "depending on the condition of the patient" The other isd more or less open heart surgery and the remove the whole part of the aorta and replace it with a rubber-type material. (
  • Primary Objective: The aim of this study is to assess the effects of Aprotinin (an antifibrinolytic drug used to reduce bleeding during cardiac surgery) on renal function in patients undergoing surgery with use of hypothermic bypass and circulatory arrest for repair of the thoracic aorta. (
  • Secondary Objective: To compare the effects of Aprotinin and Amicar on major vascular outcomes following thoracic aorta surgery with use of hypothermic bypass and circulatory arrest. (
  • Complex surgery of the ascending thoracic aorta and the aortic arch requires use of cardiopulmonary bypass (CPB) with moderate or profound total body hypothermia and circulatory arrest. (
  • When the ascending aorta tears or ruptures, the risk dying is high even if surgery is done as soon as possible. (
  • Traditionally, when the ascending aorta gets above 5.5 cm, surgery is recommended to replace the aorta. (
  • Since there are risk of waiting or doing surgery, there is currently no great support for either approach for patients with a smaller aorta. (
  • In the TITAN SvS trial, patients with an ascending aorta between 5.0 to 5.5 cm is assigned by chance to the early surgery group, in which they will undergo replacement of aorta, or the surveillance group, in which they will be closely monitored. (
  • Then more bad news: the hospital could not do the surgery to repair the aorta. (
  • After the initial surgery, Mrs. Guenther was told by the surgical team that all were cautiously optimistic of a successful recovery, and that her husband would need another surgery in a few hours to address problems in his left leg caused by the dissection of his aorta. (
  • The in-hospital mortality rates among the 27 elective and 12 emergency open descending thoracic/thoracoabdominal aortic repairs were 3.7% and 8.3%, respectively. (
  • Generally, surgical repair of the ruptured segment of aorta is associated with high rates of morbidity and mortality and in this view endovascular treatment seems to be a valid and safer alternative. (
  • Background Thoracic aortic disease has a high mortality. (
  • in the UK, mortality rates for thoracic aortic dissection and aneurysm are 3.2 and 7.5 per 100 000 inhabitants, respectively. (
  • The NO-cGMP pathway may be involved in the relaxation of DL0805 in endothelium-intact aorta. (
  • Mechanisms of adenosine triphosphate-, thrombin-, and trypsin-induced relaxation of rat thoracic aorta. (
  • Relaxation of the rat thoracic aorta with adenosine triphosphate, thrombin, and/or trypsin was associated with increased levels of cyclic guanosine monophosphate in both time- and concentration-dependent manners. (
  • There was a significant dose dependent increase in relaxation of the aorta rings with healthy and damaged endothelium. (
  • Repetitive 50 Hz pulsed electromagnetic field ameliorates the diabetes-induced impairments in the relaxation response of rat thoracic aorta rings. (
  • Tortuosity of the thoracic aorta is sometimes a sign of atherosclerotic disease, says a 2006 article in Angiology. (
  • Hussain S, Gover JL, Bree R, Bendick PJ (1989) Penetrating atherosclerotic ulcers of the thoracic aorta. (
  • We sought to determine the feasibility and potential of transesophageal magnetic resonance imaging (TEMRI) for quantifying atherosclerotic plaque burden in the aortic arch and descending thoracic aorta in comparison with transesophageal echocardiography (TEE). (
  • Using TEMRI allows for quantitative assessment of thoracic aortic atherosclerotic plaque burden. (
  • The thoracic aorta represents a valuable window on atherosclerotic plaque burden and vulnerability. (
  • Injury of the thoracic aorta refers to any injury which affects the portion of the aorta which lies within the chest cavity. (
  • In Mr. Guenther's case, the dissection had ruptured, causing a life-threatening emergency - the blood in his aorta was no longer contained within the aorta and instead, was spilling into his chest. (
  • A widened mediastinum was noted on chest radiograph, and after aortography, the patient was scheduled for emergency repair of a descending thoracic aorta disruption during general anesthesia. (
  • Procedures to repair and replace the aorta are highly specialized. (
  • 1, 2 The incidence of thoracic aortic aneurysms is estimated to be 4.5 cases per 100 000. (
  • 7 , 8 The incidence of thoracic aortic aneurysm (TAA), dissection and rupture together has been estimated for the Swedish population at 0.16 per 1000 person-years in men, and 0.09 per 1000 person-years in women, with a median age at diagnosis of 71 years and 40% overall still unruptured at diagnosis. (
  • Early diagnosis of a thoracic aneurysm is critical to managing the condition. (
  • To establish reference values for thoracic aortic diameters MDCT in healthy normotensive nonobese adults without evident cardiovascular disease. (
  • This study establishes age- and sex-specific ECG-gated MDCT reference values for thoracic aortic diameters in healthy, normotensive, nonobese adults to identify aortic pathology by MDCT. (
  • Twenty-nine patients with two CTA scans of the thoracic aorta for which the official clinical report indicated an increase in aortic diameters were included in the study. (
  • In this work, a semi-automatic software package that allows the assessment of thoracic aorta diameters from baseline and follow-up CTs (and their differences), was presented, and demonstrated high accuracy and low inter-observer variability. (
  • However, most patients that have a thoracic aortic injury do not live for 24 hours. (
  • It is difficult to rely on symptoms to diagnose a thoracic aortic injury. (
  • Repair of a thoracic aortic injury is associated with significant morbidity. (
  • Normal ascending aorta: aortic root, sinotubular junction, and supravalvular aorta. (
  • The aorta originates from the left ventricle of the heart. (
  • The initial part of the aorta, the ascending aorta, rises out of the left ventricle, from which it is separated by the aortic valve. (
  • Surgical treatment of the thoracic coarctation did not influence blood pressure which remained normal. (
  • The effect of cardiac motion on aortic flow is important when assessing sequelae in this region including coarctation of the aorta (CoA) or regurgitant fraction. (
  • Advancements in this area are particularly important for patients diagnosed with coarctation of the aorta (CoA) [ 13 - 19 ]. (
  • Fluorescence emission intensity from a culture of embryonic rat thoracic aorta medial layer ( A-10 line) myoblast cells that were transfected with a pEYFP-Actin plasmid subcellular localization vector. (
  • There are different grades to injuries to the aorta depending on the extent of injury, and the treatment whether surgical or medical depends on that grade. (
  • Injuries to the aorta are usually the result of trauma, such as deceleration and crush injuries. (
  • Many of these injuries are fatal, however those that survive deserve immediate attention - a 15 year series of 114 thoracic aorta ruptures following blunt-trauma (Maryland Shock Trauma) showed that, despite a 78% initial survival rate (resuscitation) the overall survival rate was only 47% [Cowley RA et al. (
  • However, the vast majority of thoracic aortic injuries from full frontal impacts take place when the Delta V is between 28 MPH and 84 MPH. (
  • Ascending thoracic aortic aneurysms are associated with compositional remodeling and vessel stiffening but not weakening in age-matched subjects. (
  • One LifeLike Thoracic Aorta vessel including a resealable pouch to keep product moist. (
  • Sharpness of the thoracic aorta was also evaluated quantitatively at three levels by generating a line profile across the aortic vessel wall and calculating the point spread function. (
  • The purpose of this study was to investigate 3D flow patterns and vessel wall parameters in patients with dilated ascending aorta, age-matched subjects, and healthy volunteers. (
  • 3 ] To date, two interventions are mainly used to manage this condition: The surgical repair and thoracic endovascular aortic repair. (
  • For patients with more complex conditions, open surgical repair of the aorta may be combined with another catheter-based procedure. (
  • Aprotinin Use and Renal Outcome in Hypothermic Bypass and Circulatory Arrest for Surgical Repair of Thoracic Aorta. (