The main trunk of the systemic arteries.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
Pathological processes involving any part of the AORTA.
A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
An abnormal balloon- or sac-like dilatation in the wall of AORTA.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
The nonstriated involuntary muscle tissue of blood vessels.
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.
An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
Drugs used to cause constriction of the blood vessels.
Inflammation of the wall of the AORTA.
Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Drugs used to cause dilation of the blood vessels.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.
The vessels carrying blood away from the heart.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
That phase of a muscle twitch during which a muscle returns to a resting position.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
The condition of an anatomical structure's being dilated beyond normal dimensions.
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
A diet that contributes to the development and acceleration of ATHEROGENESIS.
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
The inferior and superior venae cavae.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR).
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.
Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Elements of limited time intervals, contributing to particular results or situations.
The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.
Cholesterol present in food, especially in animal products.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.
A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
Resistance and recovery from distortion of shape.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
The act of constricting.
A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Arteries which arise from the abdominal aorta and distribute to most of the intestines.
Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.
The first and largest artery branching from the aortic arch. It distributes blood to the right side of the head and neck and to the right arm.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Pathologic deposition of calcium salts in tissues.
The main artery of the thigh, a continuation of the external iliac artery.
A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
The plan and delineation of prostheses in general or a specific prosthesis.
Operative procedures for the treatment of vascular disorders.
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.
A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.
Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Radiography of blood vessels after injection of a contrast medium.
A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
A fetal blood vessel connecting the pulmonary artery with the descending aorta.
A technique to arrest the flow of blood by lowering BODY TEMPERATURE to about 20 degrees Centigrade, usually achieved by infusing chilled perfusate. The technique provides a bloodless surgical field for complex surgeries.
Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.
Surgical incision into the chest wall.
A rare amino acid found in elastin, formed by condensation of four molecules of lysine into a pyridinium ring.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Cell surface proteins that bind THROMBOXANES with high affinity and trigger intracellular changes influencing the behavior of cells. Some thromboxane receptors act via the inositol phosphate and diacylglycerol second messenger systems.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
The veins and arteries of the HEART.
A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
The middle layer of blood vessel walls, composed principally of thin, cylindrical, smooth muscle cells and elastic tissue. It accounts for the bulk of the wall of most arteries. The smooth muscle cells are arranged in circular layers around the vessel, and the thickness of the coat varies with the size of the vessel.
The dilatation of the aortic wall behind each of the cusps of the aortic valve.
Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
A large vessel supplying the whole length of the small intestine except the superior part of the duodenum. It also supplies the cecum and the ascending part of the colon and about half the transverse part of the colon. It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra.
The flow of BLOOD through or around an organ or region of the body.
A subclass of alpha-adrenergic receptors that mediate contraction of SMOOTH MUSCLE in a variety of tissues such as ARTERIOLES; VEINS; and the UTERUS. They are usually found on postsynaptic membranes and signal through GQ-G11 G-PROTEINS.
A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE.
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Created as a republic in 1918 by Czechs and Slovaks from territories formerly part of the Austro-Hungarian Empire. The country split into the Czech Republic and Slovakia 1 January 1993.

Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (1/10763)

We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved.  (+info)

Quantification of baroreceptor influence on arterial pressure changes seen in primary angiotension-induced hypertension in dogs. (2/10763)

We studied the role of the sino-aortic baroreceptors in the gradual development of hypertension induced by prolonged administration of small amounts of angiotensin II (A II) in intact dogs and dogs with denervated sino-aortic baroreceptors. Short-term 1-hour infusions of A II(1.0-100 ng/kg per min) showed that conscious denervated dogs had twice the pressor sensitivity of intact dogs. Long-term infusions of A II at 5.0 ng/kg per min (2-3 weeks) with continuous 24-hour recordings of arterial pressure showed that intact dogs required 28 hours to reach the same level of pressure attained by denervated dogs during the 1st hour of infusion. At the 28th hour the pressure in both groups was 70% of the maximum value attained by the 7th day of infusion. Both intact and denervated dogs reached nearly the same plateau level of pressure, the magnitude being directly related both the the A II infusion rate and the daily sodium intake. Cardiac output in intact dogs initially decreased after the onset of A II infusion, but by the 5th day of infusion it was 38% above control, whereas blood volume was unchanged. Heart rate returned to normal after a reduction during the 1st day of infusion in intact dogs. Plasma renin activity could not be detected after 24 hours of A II infusion in either intact or denervated dogs. The data indicate that about 35% of the hypertensive effect of A II results from its acute pressor action, and an additional 35% of the gradual increase in arterial pressure is in large measure a result of baroreceptor resetting. We conclude that the final 30% increase in pressure seems to result from increased cardiac output, the cause of which may be decreased vascular compliance. since the blood volume remains unaltered.  (+info)

Blocking very late antigen-4 integrin decreases leukocyte entry and fatty streak formation in mice fed an atherogenic diet. (3/10763)

Atherosclerotic lesion development is characterized by the recruitment of leukocytes, principally monocytes, to the vessel wall. Considerable interest has been focused on the adhesion molecule(s) involved in leukocyte/endothelial interactions. The goal of the present study was to determine the role of the very late antigen-4 (VLA-4) integrin/ligand interaction in fatty streak development using murine models. Because alpha4 null mice are not viable, a peptidomimetic was used to block VLA-4-mediated leukocyte binding. The ability of a synthetic peptidomimetic of connecting segment-1 (CS-1 peptide) to block the recruitment of leukocytes and the accumulation of lipid in the aortic sinus of either wild-type mice (strain C57BL/6J) or mice with a low-density lipoprotein null mutation (LDLR-/-) maintained on an atherogenic diet was assessed. The active (Ac) CS-1 peptide or scrambled (Sc) CS-1 peptide was delivered subcutaneously into mice using a mini osmotic pump. Mice were exposed to the peptide for 24 to 36 hours before the onset of the atherogenic diet. In C57BL/6J mice, leukocyte entry into the aortic sinus, as assessed by en face preparations, was inhibited by the active peptide (Ac=28+/-4, Sc=54+/-6 monocytes/valve; P=0.004). Additionally, frozen sections stained with Oil Red O were analyzed to assess lipid accumulation in the aortic sinus. C57BL/6J mice that received the (Ac) compound demonstrated significantly reduced lesion areas as compared with mice that received the (Sc) peptide (Ac=4887+/-4438 microm2, Sc=15 009 +/-5619 microm2; P<0.0001). In a separate study, LDLR-/- mice were implanted with pumps containing either the (Ac) or (Sc) peptide before initiation of the atherogenic diet. Because LDLR-/- mice fed a chow diet displayed small lesions at 14 weeks, the effects of the peptide seen in these animals represented a change in early lipid accumulation rather than initiation. By using whole-mount preparations, the (Ac) but not the (Sc) peptide significantly reduced the area of lipid accumulation in the aortic sinus, resulting in an approximate 66% decrease. Plasma analysis from all studies revealed concentrations of peptide to be present at levels previously determined by in vitro analysis to block adhesion. (Ac) CS-1 peptide, which blocks VLA-4 on the leukocyte surface, is effective in reducing leukocyte recruitment and lipid accumulation in the aortic sinus. The present study provides in vivo evidence that the VLA-4 integrin plays an important role in the initiation of the atherosclerotic lesion and lipid accumulation, and it suggests a potential therapeutic strategy for this disease.  (+info)

Role of nitric oxide-cGMP pathway in adrenomedullin-induced vasodilation in the rat. (4/10763)

We previously reported that adrenomedullin (AM), a potent vasodilator peptide discovered in pheochromocytoma cells, stimulates nitric oxide (NO) release in the rat kidney. To further investigate whether the NO-cGMP pathway is involved in the mechanisms of AM-induced vasodilation, we examined the effects of E-4021, a cGMP-specific phosphodiesterase inhibitor, on AM-induced vasorelaxation in aortic rings and perfused kidneys isolated from Wistar rats. We also measured NO release from the kidneys using a chemiluminescence assay. AM (10(-10) to 10(-7) mol/L) relaxed the aorta precontracted with phenylephrine in a dose-dependent manner. Denudation of endothelium (E) attenuated the vasodilatory action of AM (10(-7) mol/L AM: intact (E+) -25.7+/-5.2% versus denuded (E-) -7. 8+/-0.6%, P<0.05). On the other hand, pretreatment with 10(-8) mol/L E-4021 augmented AM-induced vasorelaxation in the intact aorta (-49. 0+/-7.9%, P<0.05) but not in the denuded one. E-4021 also enhanced acetylcholine (ACh)-induced vasorelaxation in the rat intact aorta (10(-7) mol/L ACh -36.6+/-8.4% versus 10(-8) mol/L E-4021+10(-7) mol/L ACh -62.7+/-3.1%, P<0.05). In perfused kidneys, AM-induced vasorelaxation was also augmented by preincubation with E-4021 (10(-9) mol/L AM -15.4+/-0.6% versus 10(-8) mol/L E-4021+10(-9) mol/L AM -23.6+/-1.2%, P<0.01). AM significantly increased NO release from rat kidneys (DeltaNO: +11.3+/-0.8 fmol. min-1. g-1 kidney at 10(-9) mol/L AM), which was not affected by E-4021. E-4021 enhanced ACh-induced vasorelaxation (10(-9) mol/L ACh -9.7+/-1.7% versus 10(-8) mol/L E-4021+10(-9) mol/L ACh -18.8+/-2.9%, P<0.01) but did not affect ACh-induced NO release from the kidneys. In the aorta and the kidney, 10(-4) mol/L of NG-nitro-L-arginine methyl ester, an NO synthase inhibitor, and 10(-5) mol/L of methylene blue, a guanylate cyclase inhibitor, reduced the vasodilatory effect of AM. These results suggest that the NO-cGMP pathway is involved in the mechanism of AM-induced vasorelaxation, at least in the rat aorta and kidney.  (+info)

Different contributions of endothelin-A and endothelin-B receptors in the pathogenesis of deoxycorticosterone acetate-salt-induced hypertension in rats. (5/10763)

We investigated the involvement of actions mediated by endothelin-A (ETA) and endothelin-B (ETB) receptors in the pathogenesis of deoxycorticosterone acetate (DOCA)-salt-induced hypertension in rats. Two weeks after the start of DOCA-salt treatment, rats were given ABT-627 (10 [mg/kg]/d), a selective ETA receptor antagonist; A-192621 (30 [mg/kg]/d), a selective ETB receptor antagonist; or their vehicle for 2 weeks. Uninephrectomized rats without DOCA-salt treatment served as controls. Treatment with DOCA and salt for 2 weeks led to a mild but significant hypertension; in vehicle-treated DOCA-salt rats, systolic blood pressure increased markedly after 3 to 4 weeks. Daily administration of ABT-627 for 2 weeks almost abolished any further increases in blood pressure, whereas A-192621 did not affect the development of DOCA-salt-induced hypertension. When the degree of vascular hypertrophy of the aorta was histochemically evaluated at 4 weeks, there were significant increases in wall thickness, wall area, and wall-to-lumen ratio in vehicle-treated DOCA-salt rats compared with uninephrectomized control rats. The development of vascular hypertrophy was markedly suppressed by ABT-627. In contrast, treatment with A-192621 significantly exaggerated these vascular changes. In vehicle-treated DOCA-salt rats, renal blood flow and creatinine clearance decreased, and urinary excretion of protein, blood urea nitrogen, fractional excretion of sodium, and urinary N-acetyl-beta-glucosaminidase activity increased. Such damage was overcome by treatment with ABT-627 but not with A-192621; indeed, the latter agent led to worsening of the renal dysfunction. Histopathologic examination of the kidney in vehicle-treated DOCA-salt rats revealed tubular dilatation and atrophy as well as thickening of small arteries. Such damage was reduced in animals given ABT-627, whereas more severe histopathologic changes were observed in A-192621-treated animals. These results strongly support the view that ETA receptor-mediated action plays an important role in the pathogenesis of DOCA-salt-induced hypertension. On the other hand, it seems likely that the ETB receptor-mediated action protects against vascular and renal injuries in this model of hypertension. A selective ETA receptor antagonist is likely to be useful for treatment of subjects with mineralocorticoid-dependent hypertension, whereas ETB-selective antagonism alone is detrimental to such cases.  (+info)

AMP-activated protein kinase phosphorylation of endothelial NO synthase. (6/10763)

The AMP-activated protein kinase (AMPK) in rat skeletal and cardiac muscle is activated by vigorous exercise and ischaemic stress. Under these conditions AMPK phosphorylates and inhibits acetyl-coenzyme A carboxylase causing increased oxidation of fatty acids. Here we show that AMPK co-immunoprecipitates with cardiac endothelial NO synthase (eNOS) and phosphorylates Ser-1177 in the presence of Ca2+-calmodulin (CaM) to activate eNOS both in vitro and during ischaemia in rat hearts. In the absence of Ca2+-calmodulin, AMPK also phosphorylates eNOS at Thr-495 in the CaM-binding sequence, resulting in inhibition of eNOS activity but Thr-495 phosphorylation is unchanged during ischaemia. Phosphorylation of eNOS by the AMPK in endothelial cells and myocytes provides a further regulatory link between metabolic stress and cardiovascular function.  (+info)

RNA antisense abrogation of MAT1 induces G1 phase arrest and triggers apoptosis in aortic smooth muscle cells. (7/10763)

The human MAT1 gene (menage a trois 1) is an assembly factor and a targeting subunit of cyclin-dependent kinase (CDK)-activating kinase. The novel mechanisms by which MAT1 forms an active CDK-activating kinase and determines substrate specificity of CDK7-cyclin H are involved in the cell cycle, DNA repair, and transcription. Hyperplasia of vascular smooth muscle cells (SMC) is a fundamental pathologic feature of luminal narrowing in vascular occlusive diseases, and nothing is yet known regarding the cell cycle phase specificity of the MAT1 gene in its involvement in SMC proliferation. To investigate such novel regulatory pathways, MAT1 expression was abrogated by retrovirus-mediated gene transfer of antisense MAT1 RNA in cultured rat aortic SMCs. We show that abrogation of MAT1 expression retards SMC proliferation and inhibits cell activation from a nonproliferative state. Furthermore, we have demonstrated that these effects are due to G1 phase arrest and apoptotic cell death. Our studies indicate a link between cell cycle control and apoptosis and reveal a potential mechanism for coupling the regulation of MAT1 with G1 exit and prevention of apoptosis.  (+info)

Endogenous plasma endothelin concentrations and coronary circulation in patients with mild dilated cardiomyopathy. (8/10763)

OBJECTIVE: To determine whether increased plasma concentrations of endothelin-1 (ET-1) and big endothelin (BET) play a role in the regulation of coronary circulation in patients with idiopathic dilated cardiomyopathy (IDCM). SETTING: Tertiary referral centre for cardiac diseases. PATIENTS: Fourteen patients (eight male/six female; mean (SD) age 59 (9) years) with IDCM (ejection fraction 36 (9)%) and five normotensive subjects (two male/three female; age 52 (7) years) serving as controls were studied. METHODS: Functional status was classified according to New York Heart Association (NYHA) class. Endogenous ET-1 and BET plasma concentrations from the aorta and the coronary sinus were determined by radioimmunoassay. Coronary blood flow, using the inert chromatographic argon method, myocardial oxygen consumption, and coronary sinus oxygen content under basal conditions were determined. RESULTS: In the aorta, mean (SD) concentrations of ET-1 (IDCM 0.76 (0.25) v controls 0.31 (0.06) fmol/ml; p = 0.002) and BET (IDCM 3.58 (1.06) v controls 2.11 (0.58) fmol/ml; p = 0.014) were increased in patients with IDCM. Aortic ET-1 concentrations correlated positively with NYHA class (r = 0. 731; p < 0.001), myocardial oxygen consumption (r = 0.749; p < 0. 001), and coronary blood flow (r = 0.645; p = 0.003), but inversely with coronary sinus oxygen content (r = -0.633; p = 0.004), which was significantly decreased in IDCM patients (IDCM 4.68 (1.05) v controls 6.70 (1.06) vol%; p = 0.003). CONCLUSIONS: The coronary circulation in patients with IDCM is exposed to an increased endothelin load. ET-1 concentrations correlate with functional deterioration. A decrease of the coronary sinus content of oxygen suggests a mismatch between coronary blood flow and metabolic demand. Thus, ET-1 might be a marker of a disequilibrium between myocardial oxygen demand and coronary blood flow in IDCM.  (+info)

The SphygmoCor® CP System The SphygmoCor CP system includes pulse wave analysis (PWA) software only. During a PWA measurement, a 10-second snapshot of the radial arterial pressure wave is measured using a tonometer. The SphygmoCor software derives the ascending aortic pressure wave, substantially equivalent to the pressure wave measured by an invasive catheter. From the aortic pressure wave, a number of valuable cardiovascular measurements are determined, including central aortic systolic pressure, aortic augmentation index and central pulse pressure ...
In the present study, we addressed 2 questions that are pertinent to vascular aging. First, we determined whether aging is associated with the lengthening or elongation of the aorta and large conduit arteries. We found that the length of the ascending aorta increased significantly with advancing age, whereas the descending aorta did not demonstrate age-associated lengthening. The age-related elongation of the ascending aorta was associated with the corresponding increase in central arterial stiffness and pulse wave amplification, suggesting that the reduction in the elastic property as well as local pulsatile pressure might play a causative role. Second, we determined what impact the aortic elongation has on PWV, which is 1 of the most established measures of arterial stiffness. We found that age-related aortic elongation has little impact on PWV measurement because the segment of the ascending aorta is omitted from the arterial length measurements for carotid-femoral PWV. Moreover, the most ...
Fluid flow induced significant increases in the FGF-2 content in the circulating medium and in the pericellular region. At a shear stress level of 25 dyne/cm2, there was a 1.5-fold increase in the pericellular FGF-2 content, which represents release of 15% of the total FGF-2 in the cell (Figure 4⇑). The release was rapid in view of the fact that it occurred at ≤15 minutes and thus did not depend on the de novo synthesis of FGF-2. This release was not sustained, as seen by the decay in medium levels with time (Figure 1⇑), which can be explained by the adsorption of FGF-2 to the surfaces of the experimental system. The half-life of FGF-2 in the flow system (Figure 2⇑) is ≈4 hours. This means that FGF-2 will adsorb to surfaces after prolonged contact, and data points beyond 4 hours represent significant loss due to this adsorption. Because the release response found in the present study was rapid, adsorption did not represent a significant loss in the first 15 minutes. Furthermore, FGF-2 ...
The aorta is a large artery with a thick wall. This is necessary for it to handle a large volume of blood exiting the heart and contend with high pressure. However, there are several reasons why the inner lining of the wall can be compromised. This can cause the inner lining to tear. The blood under high pressure may then enter the wall of the aorta and create a channel for the blood between the inner and middle layer.. It is more likely to occur if the blood pressure rises to levels that are too high. Another factor is that wall of the aorta may be weakened. However, in most cases the blood may not extend beyond the middle layer of the aortic wall. Fortunately this middle layer is significantly strong to withstand the high pressure for a period of time. Eventually the blood can penetrate through the middle layer and lead to a rupture of the aorta.. Blood may then pour out of the aorta from where it bursts. As a result the blood pressure cannot be maintained at normal levels and oxygen-rich ...
enlarged aorta - MedHelps enlarged aorta Center for Information, Symptoms, Resources, Treatments and Tools for enlarged aorta. Find enlarged aorta information, treatments for enlarged aorta and enlarged aorta symptoms.
Penyakit Aneurisma Aorta - Aneurisma aorta atau aneurisme aorta merupakan pembengkakan pembuluh aorta perut atau pembesaran aorta, pembuluh darah utama yang menyalurkan darah ke tubuh pada level abdomen. Baca Juga [more…] ...
Aims - Aortic adaptive immunity plays a crucial role in atherosclerosis; however, the precise mechanisms leading to T cell activation in the arterial wall remain poorly understood. Methods and Results - Here we have identified naïve T cells in the aorta of wild-type and TCR transgenic mice and we demonstrate that naïve T cells can be primed directly in the vessel wall with a similar activation profile to splenic and lymphoid T cells. Aortic homing of naïve T cells is regulated at least in part by the P-selectin glycosylated ligand-1 (PSGL-1) receptor. In experimental atherosclerosis the aorta supports CD4+ T cell activation selectively driving Th1 polarization. By contrast, secondary lymphoid organs display Treg expansion. Conclusions - Our results demonstrate that the aorta can support T cell priming and that naïve T cells traffic between the circulation and vessel wall. These data underpin the paradigm that local priming of T cells specific for plaque antigens contributes to atherosclerosis
A method and device for occluding a patients ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patients heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula or the aortic occlusion catheter.
Enlargement of the ascending aorta indicates a weakening of the aortic wall, according to Cedars-Sinai. Often, an enlarged ascending aorta is diagnosed as an aneurysm....
MicroRNAs have been demonstrated to be involved in the development of atherosclerosis. The present study aimed to evaluate the effect of miR-99a-5p and its target gene Homeobox A1 (HOXA1) in atherosclerosis.The biological functions of miR-99a-5p on human aortic smooth muscle cells (ASMCs) were assessed by MTT, wound healing and transwell assays. The target genes of microRNAs were predicted by Targ ...
The paired dorsal aorta is the first recognizable vessels in the embryo. These bilaterally positioned vessels are fused at the axial level, during the first four weeks of gestation in humans, to form a single midline dorsal aorta.. ...
noun the descending part of the aorta that branches into the thoracic and abdominal aortae • Hypernyms: ↑aorta * * * noun : the part of the aorta from the arch to its bifurcation that passes downward in the thoracic and abdominal cavities
ATCC offers cell lines derived from the normal aorta of human, mouse and rat, as well as primary aortic smooth muscle cells from human.
ATCC offers cell lines derived from the normal aorta of human, mouse and rat, as well as primary aortic smooth muscle cells from human.
TY - JOUR. T1 - Non-invasive assessment of wave reflection phenomena in the central aorta. AU - Avolio, Alberto. AU - Cook, David. AU - Old, R. AU - Halliday, A. PY - 2002. Y1 - 2002. M3 - Conference paper. SP - 895. EP - 895. JO - Journal of Hypertension. T2 - Journal of Hypertension. JF - Journal of Hypertension. SN - 1473-5598. ER - ...
Study Flashcards On Ascending Aorta at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Presented in this paper are 3 cases of hemorrhage of ascending aorta and left ventricle after open heart surgery treated by extracardial bypass in our hospital from Oct. 1994 to Dec. 1995. Remained aneurysmal wall enclosing conduit graft was used as
Source: Adapted from the National Institutes of Health. What does the term aorta mean? The term aorta refers to the large artery that carries blood from the heart to the rest of body. To find out more about this term, please search the news section of this website for related articles and information.. ...
Individual evaluation of each patient, and each aorta, is key to durable repair. The instructions for use (IFU) are not a clinical guideline, so trainees should really think about what the main considerations are when they are implanting devices in the aorta to create a durable repair, said Tara Mastracci (Royal Free Hospital, London, UK) at the London Aortic Symposium 2018. Mastracci told Interventional News about how clinicians practices are being tested on the durability of aortic repair and how it is vital for operators to audit and evaluate their own data.. ...
НИИ атеросклероза: научные исследования, публикации сотрудников института (abstracts, full-text.), дискуссионный клуб, посвященный вопросам механизмов атерогенеза.
I was diagnosed in 2012 with ascending aorta dialation of 4.1 cm. In 2013 no change. Finally went back to dr in 2017 and echo showed 4.3 cm. 2 months later dr made me have a chest scan which read 4.5 cm. which is correct? Echo or scan? Dr wants […]
Survival Technology - SonoSims new aorta and IVC real-patient scanning cases are available in the Aorta/IVC Core Clinical Module
Tortous Aorta is the problem related to the largest artery in our body- the aorta and is mostly found in small infants. It is curable and many patients lead a normal life after proper medication and treatment.
liekamoji dešinioji aorta statusas T sritis gyvūnų raida, augimas, ontogenezė, embriologija atitikmenys: lot. Aorta dextra persistens ryšiai: platesnis terminas - kraujagyslių ydos
Relaxation of Rat Aorta by Farrerol Correlates with Potency to Reduce Intracellular Calcium of VSMCs. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Researchers investigate the role of arterial stiffness in memory decline in older adults. A flexible aorta may be key to maintaining cognitive ability.
I am scheduled to undergo these procedures next week. ascd aorta 5.5, root 5.0, afib for several months now. Any advice out there, I am starting to get...
3) Liu X, Pu F, Fan YB, Deng XY, Li DY, Li SY(李淑宇). A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch. Am J Physiol Heart Circ Physiol, 2009, 297(1):163-170 ...
НИИ атеросклероза: научные исследования, публикации сотрудников института (abstracts, full-text.), дискуссионный клуб, посвященный вопросам механизмов атерогенеза.
Occasionally, in an aorta diseased by arteriosclerosis, a tear de-velops in the intima or the media degenerates, resulting in a dis-section .
Hello, My daughter is seven and half years old. she had an open heart surgery in 2007 for closure of VSD. and till then echo is going on every year. Her Aorta size is 3.1 (Z score - 4.9) and it...
Read interesting answers and in fact write your own answer to the question Why blood entering the aorta from the reservoir flows into the heart?
The revision #92494 of the page named Aorta VI does not exist. This is usually caused by following an outdated history link to a page that has been deleted. Details can be found in the deletion log. ...
Aorta The Heart of Art is a Limited Liability Company Registered in England & Wales. Company Number 08878163. VAT Registration Number 206 050 753 ...
Aorta The Heart of Art is a Limited Liability Company Registered in England & Wales. Company Number 08878163. VAT Registration Number 206 050 753 ...
Az aorta stenosisban (AS) szenved szem lyek k z tt gyakori a magas v rnyom s s a v rnyom s optim lis cs kkent se sz ks ges az art ri s terhel s s a cardiovascularis esem nyek m rs kl s hez. Nem ismert, hogy a kalciumcsatorna-g tl k (CCB) biztons gosnak tekinthet k-e. K zepes vagy s lyos fok , ...
The aorta of mice involves certain challenges, such as resolution and partial volume effects. As all the animals have been treated similarly, the problems are
Terms & Conditions: Ticket sales include admission to AORTA Level 3 course, face to face training session on the chosen date of this registration. Please note your place is NOT confirmed until full payment is received and confirmation sent and received. We do not suggest booking any flights or accommodation until confirmation is received. We do accept attendee transfers between professional colleagues, however, changes in levels of registrations will not be refunded. Notice Period Supplied: 100% refund - by 30 days prior to the scheduled event or a change of selected date is acceptable ...
Treatment for an enlarged aorta depends on a variety of factors, including age and body size, medical history and the position and size of the enlargement.
Dont miss out on the latest Cta Abd Aorta Bi Iliofem Coupon right HERE. Pick one of our tested and updated vouchers - 100% verified and working ...
Aorta - Dictionar termeni medicali - Vas de sange important care preia sangele pompat de inima si din care pleaca vase mari catre intreg organismul. Principala artera a organismului, formandu-se de la baza ventriculului stang si distribuind
What makes the Aorta Kukri blade great, is its ability to make deep penetrating cuts while piercing with ease as well as its ability to be moved quickly.
Saya (56 tahun) didiagnosis dokter mengidap penyakit aneurisma aorta bagian abdomen. Dari jantung kearah ginjal terjadi pembengkakan. Dokter menyarankan untuk
Differential effects on aortic segments could provide novel insights into the pathophysiology of increased arterial stiffness in CKD and potentially in various
Program:Aorta betegs gei9.00- 9.20- Prenatalis diagnosztika. Dr. Lad nyi Anik Bicuspidalis aorta billenty 9.30-9.50 Bicuspidalis aorta billenty - plasztika feln tt korban- seb szeti lehet s gek, eredm nyek- Dr. Sz...
TY - JOUR. T1 - Glucose alters platelet-derived growth factor-BB activity in human aortic vascular smooth muscle cells by stimulating protein phosphatase 2A in a protein kinase C-beta II-dependent pathway. AU - Campbell, Malcolm. AU - Trimble, Elizabeth. PY - 2004/9. Y1 - 2004/9. M3 - Article. VL - 47. SP - A445-A445. JO - Diabetologia. JF - Diabetologia. SN - 0012-186X. ER - ...
Hello. I need to culture bovine aortic smooth muscle cell. I do not know what medium should be used. What supplements or growth factors are required? In how much in amount? Please give me some help. Thanks in advance ...
Mouse Aortic Vascular Smooth Muscle Cells from Creative Bioarray are isolated from tissue of New Zealand White Rabbits. Rabbits Aortic Vascular Smooth Muscle Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Creative Bioarrays Cell Culture Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen ...
Citation: Kumari, R. et al. (2003) ATP and UTP responses of cultured rat aortic smooth muscle cells revisited: Dominance of P2Y2 receptors. British Journal of Pharmacology, 140 (7), pp. 1169-1176. ...
TY - GEN. T1 - Multilayer properties of aorta. AU - Parenti, C.. AU - Laksari, K.. AU - Shafieian, M.. AU - Darvish, K.. PY - 2009/9/21. Y1 - 2009/9/21. N2 - Current finite element models of the aorta assume a homogenous material, but in fact aorta is composed of three major layers. Understanding of the material properties of these layers is essential in order to study the local mechanism of dynamic rupture. The material properties of aorta wall layers were determined from micro indentation tests. The results showed significant linear increase of the shear modulus in the inner half of media. A dominant viscoelastic behavior was observed which was almost uniform throughout the layers.. AB - Current finite element models of the aorta assume a homogenous material, but in fact aorta is composed of three major layers. Understanding of the material properties of these layers is essential in order to study the local mechanism of dynamic rupture. The material properties of aorta wall layers were ...
Liu, J.P., Komachi, M., Tomura, H., Mogi, C., Damirin, A., Tobo, M., Takano, M., Nochi, H., Tamoto, K., Sato, K., et al. (2010). Ovarian cancer G protein-coupled receptor 1-dependent and -independent vascular actions to acidic pH in human aortic smooth muscle cells. Am J Physiol Heart Circ Physiol 299, H731-742 ...
Volume 32: D-Carvone, a Monoterpene Reverses Alterations in Heart Rate, Nitric Oxide, Aortic Lipids and Enzymatic Antioxidant Status in Nitric Oxide Deficient Hypertensive Rats
Aorta functions not only as a conduit delivering blood to the tissues but also as an important modulator of the entire cardiovascular system, buffering the intermittent pulsatile output from the heart to provide steady flow to capillary beds.1 By virtue of its elastic properties, aorta influences left ventricular function and coronary blood flow.2 3 4 5 Systemic hypertension, a common disorder with potentially serious complications, exerts further ill effects through structural and functional modifications of the arterial wall.6 7 Previous studies using different techniques have shown that aortic elastic properties are compromised in patients with arterial hypertension.8 9 10 11 12 13 14 Measurement of pulse wave velocity has been extensively used,9 10 11 providing only indirect estimations of the elastic properties of the aorta. Noninvasive methods11 12 13 14 using formulas involving pulsatile change in aortic dimensions and pulse pressure (the former is measured with echocardiography or ...
TY - JOUR. T1 - Impact of treatment modality on vascular function in coarctation of the aorta. T2 - The LOVE-COARCT study. AU - LOVE-COARCT Study. AU - Martins, José D.. AU - Zachariah, Justin. AU - Tierney, Elif Seda Selamet. AU - Truong, Uyen. AU - Morris, Shaine A.. AU - Kutty, Shelby. AU - de Ferranti, Sarah D.. AU - Guarino, Maria. AU - Thomas, Boban. AU - Oliveira, Diana. AU - Marinho, António. AU - António, Marta. AU - Gauvreau, Kimberlee. AU - Jalles, Nuno. AU - Geva, Tal. AU - Carmo, Miguel M.. AU - Prakash, Ashwin. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Background-Optimally treated patients with coarctation of the aorta remain at risk for late vascular dysfunction. The effect of treatment modality on vascular function is unknown. The LOVE-COARCT (Long-term Outcomes and Vascular Evaluation After Successful Coarctation of the Aorta Treatment) study was done to compare vascular function in patients with coarctation of the aorta treated with surgery, balloon dilation (BD), or stent ...
The aorta originates from the left ventricle of the heart. It ends in the abdomen where it branches into the two common iliac arteries. The aorta has five separate segments. The descending aorta begins at the arch of the aorta (where it loops over the heart to begin its descent).
The functions of resident CD11c+ myeloid cells in healthy mouse aorta and in the initiation of atherosclerosis. In atherosclerotic lesions, myeloid cells (macrophages and dendritic cells) and oxidatively-modified lipids accumulate underneath the endothelium in the arterial intima (the inner layer of the artery facing the lumen). Previously, we showed that in the normal mouse aorta CD11c+ myeloid cells reside preferentially in regions predisposed to atherosclerosis. Upon feeding a high cholesterol diet to atherosclerosis-susceptible low-density lipoprotein receptor deficient (LDLR-/-) mice, intimal CD11c+ cells accumulate intracellular lipid even prior to the recruitment of blood monocytes. Collectively, our studies showed that the low-grade monocyte recruitment in lesion-prone regions of the aorta accounts for resident intimal CD11c+ myeloid cell accumulation in the steady state, and that these cells promote atherosclerotic lesion formation and monocyte recruitment to the aortic intima in the ...
The air-filled ring was initially placed around the ascending aorta through a small tunnel in the periaortic fat. Extreme care was taken to avoid, as far as possible, damage of the penetrating vasa vasorum.1 When the hemodynamic condition of the animal was considered stable, the filling pressure of the ring was adjusted to be 60 mm Hg at diastole; this filling pressure was in every case below the aortic diastolic pressure of the animal, so that the ring would be in gentle contact with the aortic wall. At systole, the filling pressure of the ring increased by approximately 5 mm Hg because of the distension of the aorta (the exact value depended on the amount of distension of the aorta). Conditions of contact between the ring and the aortic wall were stable throughout the experiment. After placement of the ring, changes of the aortic diameter were recorded simultaneously with the ECG and the aortic pressures at a paper speed of 50 mm/s. To evaluate the data of each experimental subject, 10 ...
Human Aortic Endothelial Cell Genomic DNA https://www.sciencepro.com.br/produtos/sc-6109 https://www.sciencepro.com.br/@@site-logo/logo-novo.png ...
7-Ketocholesterol predisposes human aorta smooth muscle cells to Fas-mediated death / Mun Chual Rho; Young Kook Kim; Jong Sun Chang; Hyun Sun Lee; Jin Ah Baek; Mi Yeon Chung; H C Lee; H W Lee; B Y Rhim; M A Reidy; K Kim , 2005 ...
We thank Dr. Nelson and colleagues for their interest in our recent work concerning the effect of age on the biomechanical properties of the human aorta (1). We observed the greatest age-related difference in the aortic pulse wave velocity in the distal abdominal aorta, and the least in the aortic arch, suggesting that the distal aorta stiffened most with age. As we noted in our discussion, and as Dr. Nelson and colleagues reiterate, others have reported the converse, that is, that the ascending aorta stiffens most with age (2,3). No doubt, there are several explanations for these discrepant observations, not least the very small sample sizes reported by some authors (2,3), the use of differing techniques to estimate regional stiffness, methodological issues such as the use of nonsimultaneous, peripheral pressure when calculating distensibility/compliance (3), and technical issues such as inaccurate edge detection with cardiac magnetic resonance with varying sequences (4). Interestingly, a ...
Causes of Coarctation of aorta dominant including triggers, hidden medical causes of Coarctation of aorta dominant, risk factors, and what causes Coarctation of aorta dominant.
A Riddle of Esophagography: Where Do the Descending Aorta and the Abdominal Aorta Run in Cases of the Right Aortic Arch? Report of two cases, Sugiura Y, Sh
De opstiegende Aorta oder medizinsch Aorta ascendens, de vun de linke Hartkamer meist pielliek na baven löpt un vun de Kamer dör de Aortenklapp afscheedt is. Se liggt vullstännig in de Hartbütelhöhl (Perikardhöhl) un is blots wenige Zentimeter lang. De licht bukig utwiete Anfangsdeel vun de Aorta (Aortenbulbus oder Bulbus aortae) besteiht ut de dree Sinus valsalvae (ok: Sinus aortae), de vunn Sluutrand vunn enkelten Aortenklappenseil un vun de Aortenwand afgrenzt warrt. Ut den vörderen un den linken Sinus valsalvae kummt direkt ant Hart de Hartkranzfatten (Arteriae coronales) rut, de den Hartmuskel versorgt ...
BioAssay record AID 577806 submitted by ChEMBL: Inhibition of 1-Nitrosocyclohexyl acetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 0.1 to 1 mM.
How is comparison, aortic endothelial cells abbreviated? PAEC stands for comparison, aortic endothelial cells. PAEC is defined as comparison, aortic endothelial cells rarely.
LIGATION OF THE ABDOMINAL AORTA: REPORT OF THE ULTIMATE RESULT, ONE YEAR, FIVE MONTHS AND NINE DAYS AFTER LIGATION OF THE ABDOMINAL AORTA FOR ANEURISM AT THE BI
During an abdominal aorta scan, the mobile technologist uses two types of ultrasound to systematically interrogate the entire length of the abdominal aorta. He
What is aortic disease? Aortic disease is a form of peripheral artery disease that affects the aorta, the largest artery in the body. The aorta is about the thickness of a garden hose and runs from your heart through your chest and abdomen, carryin
What is aortic disease? Aortic disease is a form of peripheral artery disease that affects the aorta, the largest artery in the body. The aorta is about the
When someone has coarctation of the aorta, that persons aorta (the major blood vessel that carries blood away from the heart to the body) is narrowed at some point.
Coarctation of the aorta (COA) is a narrowing of the aorta, the major blood vessel that carries blood away from the heart to the body.
Coarctation of the aorta (COA) is a narrowing of the aorta, the major blood vessel that carries blood away from the heart to the body.
When someone has coarctation of the aorta, that persons aorta (the major blood vessel that carries blood away from the heart to the body) is narrowed at some point.
Coarctation of the aorta is a heart defect that is present at birth (congenital). It means the aorta is narrower than it should be. Read on to learn details about the condition.
Coarctation of the aorta is a heart defect that is present at birth (congenital). It means the aorta is narrower than it should be. Read on to learn details about the condition.
Coarctation of the aorta is a narrowing of the aorta. It can lead to worsening heart function over time, but effective treatments are available.
Xinmai Medical (688016) In-depth report: Domestic aorta and prolonged vascular intervention faucet. Report Summary Xinmai Xinmai Medical is currently the leading domestic manufacturer of aortic and vascular interventional products, with rich products and leading market share.. The company developed and launched the worlds first split-type stent graft in the field of thoracic aorta stent grafts. In the field of abdominal aortic stent grafts, although there is still a gap with imported products, it is gradually upgraded and is expected to achieve import substitution.. The layout of distal vascular interventional devices is extensive and rich. Drug replacement balloons have been applied for marketing, and the market potential has broken through.. The company has rich research reserves, continuous high-intensity research and development, and expansion of innovation capabilities. It is a leader in aortic intervention and interventional vascular 苏州桑拿网 disease segmentation.. The domestic ...
Arterial glycosaminoglycans are considered to be important in atherogenesis due to their ability to trap lipid inside the vessel wall and to influence cellular migration and proliferation. Atherosclerotic lesions have displayed an altered glycosaminoglycan content and distribution. Diabetes is a rec …
Aorta definition is - the great arterial trunk that carries blood from the heart to be distributed by branch arteries through the body.
The Aorta/Vein Punch from Wexler Surgical is made of Stainless Steel. The punch has a 3.0mm tip and a rounded handle. Total length of the Aorta/Vein Punch is...
Anevrismul aortic reprezinta o zona slabita si „umflata in peretele aortei. Aorta este vasul de sange de dimensiuni mari, care transporta sangele bogat in oxigen de la inima la restul organismului. Aorta anevrismala este slabita si se poate rupe, determinand o hemoragie ce poate pune in pericol viata. Ruperea anevrismului aortic este pe locul 15 in lista cauzelor de deces si apare la una din 12 persoane in varsta. Exista 2 tipuri de anevrism aortic: anevrismul aortic abdominal si anevrismul aortic toracic. Aceasta clasificare se bazeaza pe localizarea anevrismului de-a lungul traiectului aortei. Regiunea toracica a aortei traverseaza partea de sus (toracica) a corpului si furnizeaza sange bogat in oxigen in aceasta regiune. Regiunea abdominala a aortei este in continuarea celei toracice, de-a lungul abdomenului si asigura aportul de sange bogat in oxigen in partea de jos a corpului. Anevrismele pot aparea in orice zona a aortei, dar cel mai frecvent apar in partea abdominala.. #gallery-1 { ...
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Double aortic arch is a common form of a group of defects that affect the development of the aorta in the womb. These defects cause an abnormal formation called a vascular ring (a circle of blood vessels).. Normally, the aorta develops from one of several curved pieces of tissue (arches). As babies develop in the womb, the arches split into several parts. The body breaks down some of the arches, while others form into arteries. A normally developed aorta is a single arch that leaves the heart and moves leftward.. In double aortic arch, some of the arches that should have disappeared are still present at birth in addition to the normal arch. Babies with a double aortic arch have an aorta that is made up of two vessels instead of one. The two parts to the aorta have smaller arteries branching off of them. As a result, the two branches go around and press down on the windpipe and the tube (esophagus) that carries food from the mouth to the stomach. A double aortic arch may occur in other congenital ...
An impedance pump - also known as Liebau pump - is a simple valveless pump that operates based on the principles of wave propagation and reflection. It has been shown in embryonic zebrafish that a similar mechanism is responsible for the pumping action in the embryonic heart during the early stages before valve formation.... Go to the Article ...
FIGURE 1. (A) Schematic setup of the stereo-vision system to focus on a specimen, (B) specimen images taken by each camera, and (C) the reconstructed positions of markers affixed to the specimen in the 3D coordinate system. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.] - Longitudinal differences in the mechanical properties of the thoracic aorta depend on circumferential regions.
The aim of this study was to explore the clinical impact of transverse aortic arch hypoplasia (TAH) after stent implementation for isthmal coarctation of the aorta (CoA). From a retrospective chart...
The gradient across coarctation is not simply (& solely ) determined by degree of obstruction , as one would believe.Understanding the hemodynamics and various factors that can influence the gradient is essential Relieving the obstruction /gradient by stent or surgery may not be synonymous with successful treatment as we understand now the entire aorta right…
Learn more about the possible symptoms of coarctation of the aorta, including hypertension, chest pain, claudication, and headaches.
We need to stay vigilant for the needles in the haystack of pediatric illnesses. One of those needles is Coarctation of the Aorta.
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Helpful, trusted answers from doctors: Dr. Hahn on aorta fem bypass: A coronary artery bypass brings more blood to the heart muscle by connecting a new tube(vein or artery) past a blockage in an artery on the heart.
A blood vessel of arterial type, which is the largest artery in the human body. It originates from the left ventricle of the heart and ends in the pelvis, where it divides into two femoral arteries, each of which supplies one of the lower extremities, the right and the left, respectively. Along its entire course, smaller arteries originate from the aorta, which supply oxygenated blood to all body organs.. ...
HABERMAN, Diego et al. The 64 multi detector row computed tomography in aortic patology diagnostic. Rev. argent. radiol. [online]. 2008, vol.72, n.3, pp.277-286. ISSN 1852-9992.. The angio computed tomography represents a great utility diagnostic method that has reached greater importance with its technological new developments. The 64 multi detector row computed tomography allows the evaluation with great precision and detail of very small structures, offering a new perspective in aortic patology diagnostic.. Palabras clave : Angiotomography; Aorta; Aneurysm; Dissection; Coartation; Arteritis. ...
Infection in the aorta (vasculitis). In rare cases, abdominal aortic aneurysm may be caused by an infection or inflammation ... All types of abdominal aortic aneurysms occur in the part of the aorta that passes through the middle to low abdomen. Thoracic ... Smoking may also cause an aneurysm to grow faster by further damaging the aorta. Hardening of the arteries (atherosclerosis). ... aortic aneurysms occur on the aorta as it passes through the chest cavity. These are less common than abdominal aneurysms. ...
Bramwell, C. (April 1947). "Coarctation of the aorta: II. Clinical features". Br Heart J. 9 (2): 100-127. doi:10.1136/hrt.9.2. ... with A. Morgan Jones: Bramwell, C.; Jones, A. M. (October 1941). "Coarctation of the aorta: the collateral circulation". Br. ...
The abdominal aorta and its branches. Vessels of the uterus and its appendages, rear view. Uterus and right broad ligament, ... It arises from the abdominal aorta below the renal artery. It can be found in the suspensory ligament of the ovary, anterior to ... The ovarian arteries are paired structures that arise from the abdominal aorta, usually at the level of L2. After emerging from ... the aorta, the artery travels down the suspensory ligament of the ovary, enters the mesovarium, and may anastamose with the ...
SA begins as inflammation of the outermost layer of the blood vessel, including the blood vessels that supply the aorta itself ... September-October 2015). "Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology ... Syphilitic aortitis is inflammation of the aorta associated with the tertiary stage of syphilis infection. ... chest pain and shortness of breath might appear as a result of the damage of the aorta and heart valve.[citation needed] ...
Later in 1913, Hirschfelder published part II of his book on Diseases of the Heart and Aorta. In this, he discussed the effects ... Hirschfelder, Arthur (1910). Diseases of the Heart and Aorta. Philadelphia, Pennsylvania: J.B. Lippincott & Co. pp. 184-186, ... Hirschfelder published Disease of the Heart and Aorta which was highly influential and regarded as the first complete monograph ...
When the set-up is ready, the aorta is clamped shut with a cross-clamp to stop blood pumping through the heart and cardioplegia ... It separates the heart from the aorta. Each cusp is attached to the aortic wall creating a sinus; a Valsalva sinus. The origins ... The surgeon incises the aorta a few milometers above the sinotubular junction (just above the coronary ostia, where the ... Once the valve is in place and the aorta has been closed, patient is placed in a Trendelenburg position and the heart is de- ...
Deeg, KH; Hofbeck, M; Singer, H (December 1993). "Diagnosis of subclavian steal in infants with coarctation of the aorta and ... blood flows from the aorta into the subclavian artery, and then some of that blood leaves via the vertebral artery to supply ... "Cerebrovascular abnormalities in postoperative coarctation of aorta. Four cases demonstrating left subclavian steal on ...
Experience with infected aneurysms of the abdominal aorta. Arch Surg. 1975;110:1281-1286. Mycotic (Infected) Aneurysm Caused by ...
The thoracic aorta, viewed from the left side. Sympathetic connections of the ciliary and superior cervical ganglia. v t e. ...
March 2005). "Tracheal regeneration following tracheal replacement with an allogenic aorta". The Annals of Thoracic Surgery. 79 ...
In the first use of these catheters in humans, each catheter was specifically shaped to match the size and shape of the aorta ... His initial work involved shaping stiff wires and comparing those shapes to radiographs of the ascending aorta to determine if ... Occlusive aortography involved the transient occlusion of the aorta and subsequent injection of a small amount of radiographic ... Palmaz JC, Windeler SA, Garcia F, Tio FO, Sibbitt RR, Reuter SR (1986). "Atherosclerotic rabbit aortas: expandable intraluminal ...
The aorta and pulmonary artery can also be side by side, with aorta on either side. This is a less common variant, and with ... The procedure involves transecting both the aorta and pulmonary artery; the coronary arteries are then detached from the aorta ... In the majority of d-TGA cases, the aorta is anterior and to the right of the pulmonary artery, but it can also be directly ... The oxygen-rich ("red") blood then returns to the left heart, via the pulmonary veins, and is pumped through the aorta to the ...
LearningRadiology.com > Coarctation Of the Aorta Retrieved August 2010 "Medcyclopaedia - Rib notching". Retrieved 2010-04-15.. ...
In 1961, after recalling that cloth grafts had been used in the aortas of pigs, he used his nylon shirt to successfully repair ... After debriding and resecting the aneurysm, the two open ends of the aorta needed to be rejoined with a graft, but the surgeons ... Rob, Charles (November 1955). "The Surgery of the Abdominal Aorta and its Major Branches". Annals of the Royal College of ... known as carotid endarterectomy and of the aorta when treating aortic aneurysms. After graduating from Cambridge University and ...
Cardiovascular system: Relapsing polychrondritis may cause inflammation of the aorta. It can also cause leaky heart valves ( ...
These tissues especially include the lungs (pumice lung) and the aorta. Dystrophic calcification, without a systemic mineral ...
Inflammation of the heart muscles, coronary arteries, and aorta is rare. For those who are infected, a complete blood count may ...
The diastolic blood pressure in the aorta falls, due to regurgitation. This increases pulse pressure.[citation needed] Mitral ... afterload because the LV must work harder to eject blood into the aorta. This is because the aortic valve won't open until the ... the left ventricle has to generate a pressure of 110 mmHg to open the aortic valve and eject blood into the aorta.[citation ... in addition to the blood pressure required to eject blood into the aorta. For instance, if the blood pressure is 120/80, and ...
Aorta walks in and threatens to kill George for stealing his fiancé. To save George, Glorice reveals "her" tool, shocking Aorta ... The two try introducing Aorta to other women, but none can match up to Glorice because, as Aorta says, "She's got balls". The ... But the date doesn't go well, and Aorta ends up with plate of spaghetti on his head. Fortunately, Aorta likes Glorice's tough ... Aorta announces his engagement to Glorice with George to be best man, and the beautiful moll reveals to George her plan of ...
Cardiovascular abnormalities include ventricular septal defect and coarctation of the aorta; urinary system issues include ...
It receives its blood supply from vessels that connect to the aorta and cover the primitive foregut. These attachments to the ... In ILS, the arterial supply is usually derived from the lower thoracic or upper abdominal aorta. Venous drainage is usually to ... In general, the arterial supply of ELS comes from an aberrant vessel from thoracic aorta. It usually drains via the systemic ... Doppler studies are helpful to identify the characteristic aberrant systemic artery that arises from the aorta and to delineate ...
... female patient's own aorta was grafted from the arch to the descending thoracic aorta and the left subclavian artery was ... in which a vein was used to connect the ascending aorta and the descending aorta. The first successful repair of a Type C ... in which the 16-year-old female patient's ascending aorta was grafted to the descending thoracic aorta. As of 1984, there had ... There is a gap between the ascending and descending thoracic aorta. In a sense it is the complete form of a coarctation of the ...
Following this, the aorta, cava, and portal veins of the donor and recipient are anastomosed. The graft is then flushed before ... In the next step, the aorta is cross-clamped, cutting off blood supply to the organs. Once blood and oxygen supply to an organ ... The aorta and vena cava are dissected in preparation for vascular anastomosis, followed by dissection of the proximal and ... Arterial vessels are connected to the abdominal aorta, below the kidneys. However, venous drainage, or the reattachment of the ...
A case of aneurism of the Aorta, communicating with the Pulmonary artery. A case of considerable enlargement of the Cœcum and ...
Despite the presence of nodules 2-cm in diameter on aorta walls and heart tissue, and narrowing of the aorta, almost all ... They make aneurysmal (i.e. bulging) nodules in the wall of the aorta, which can be up to 2 cm in diameter. The male lives ... Despite the fact that it lives in nodules (aneurysms) in the walls of the aorta and heart, apparent clinical symptoms of E. ... Corrugated and migratory tract lesions on the inner wall of the aorta and fibrin strands attached to the nodules have also been ...
The ductus arteriosus is a small blood vessel connecting the pulmonary artery to the aorta of a foetus. Since the foetus ... Taussig, Helen B.; Bing, Richard J. (1949). "Complete transposition of the aorta and a levoposition of the pulmonary artery". ... a set of rare congenital heart conditions in which the aorta, which is supposed to carry oxygen-rich blood from the left ...
Poor systemic circulation also results due to improper positioning of the aorta. Left atrial appendage isomerism, also called ...
Corpescu sent his wives, Hemata, Pulmona and Aorta against the Crossover clan. All enemies converge on the unsuspecting ...
Ao~rta Project, BBK Kunst Forum, Düsseldorf and Ausstellungshalle Innenhafen, Duisburg, Germany. He has received a number of ...
The cause was later determined to be a traumatic rupture of the aorta. "Probespieler Elejiko keine Alternative für Jena (On- ...
Treatments and Tools for enlarged aorta. Find enlarged aorta information, treatments for enlarged aorta and enlarged aorta ... MedHelps enlarged aorta Center for Information, Symptoms, Resources, ... Posts on enlarged aorta. enlarged aorta 3.8cm - Heart Disease Expert Forum ... I have controlled high blood pressure,and enlarged aorta. Will my aorta ever go back to its... ...
A flexible aorta may be key to maintaining cognitive ability. ... A supple aorta might slow brain aging. Written by Tim Newman on ... The aorta is the main artery in the body, carrying blood from the heart and down through the abdomen before splitting off into ... The role of the aorta. In particular, the team is interested in the potential relationship between cognitive decline and the ... A healthier, more elastic aorta is also theorized to protect cognitive function by reducing the negative effects of excessive ...
He has been diagnosed with an enlarged Aorta and been told that something will need to be done within the next five years. He ... Enlarged Aorta gaving I live in the UK and my best friend and I have turned 50 this year. He has been diagnosed with an ... Enlarged Aorta. I live in the UK and my best friend and I have turned 50 this year. He has been diagnosed with an enlarged ... We are both big Pittsburgh Steelers and Penguins fans and I see that there is big developments in Aorta procedures in the ...
ATCC offers cell lines derived from the normal aorta of human, mouse and rat, as well as primary aortic smooth muscle cells ...
An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes ... A method and device for occluding a patients ascending aorta, maintaining circulation of oxygenated blood in the patient and ... The opening also provides direct access to the ascending aorta for control of the ascending aorta and to place purse-string ... Catheter with an aorta-occluding balloon. US5428070. 11 Jun 1993. 27 Jun 1995. The Board Of Trustees Of The Leland Stanford ...
... - Vas de sange important care preia sangele pompat de inima si din care pleaca vase mari ... Aorta Antireumatismal Angiogranulom Adipoza Alogrefa Anizocromie Adductor Ablefarie Apgar (cotare a lui) Antiseptice pentru uz ...
SUNY Figs 21:06-00 - "Branches of the ascending aorta, arch of the aorta, and the descending aorta." ... thoracic aorta. visceral: bronchial - esophageal - mediastinal parietal: posterior intercostal 3-11 - subcostal - superior ... The esophageal arteries four or five in number, arise from the front of the aorta, and pass obliquely downward to the esophagus ... Retrieved from "https://www.wikidoc.org/index.php?title=Esophageal_branches_of_thoracic_part_of_aorta&oldid=673813" ...
Why blood entering the aorta from the reservoir flows into the heart? ... Why blood entering the aorta from the reservoir flows into the heart?. Asked by John Adney, Last updated: Dec 05, 2017 ...
The revision #92494 of the page named "Aorta VI" does not exist. ...
... the aorta and is mostly found in small infants. It is curable and many patients lead a normal life after proper medication and ... Tortous Aorta is the problem related to the largest artery in our body- ... Aorta is one of the biggest arteries and delivers blood to the many organs in the body. A tortuous aorta is when it curves down ... What is Aorta?. The aorta is the largest artery in our body and supplies oxygenated blood to the body from the heart. It is ...
The ascending aorta was longer with advancing age (r = 0.72) whereas the lengths of the descending aorta did not change. The ... Conclusions The aorta lengthens with age, even in healthy humans, due primarily to the elongation of the ascending aorta. Age- ... We concluded that the aorta lengthens with age even in healthy humans due to the elongation of the ascending aorta. Age-related ... Results The ascending aorta was greater with advancing age (r = 0.72), whereas the lengths of the descending aorta and carotid ...
Az aorta stenosisban (AS) szenved szem lyek k z tt gyakori a magas v rnyom s s a v rnyom s optim lis cs kkent se sz ks ges az ... A m rs kelt vagy s lyos aorta stenosisban szenved betegek antihypertensiv kezel se kalciumcsatorna-g tl kkal: sszef gg s a ... A k zepes vagy s lyos aorta stenosisban szenved t netmentes betegekben az antihypertensiv kezel s c lj b l adott ...
ascd aorta 5.5, root 5.0, afib for several months now. Any advice out there, I am starting to get... ... ascd aorta 5.5, root 5.0, afib for several months now. Any advice out there, I am starting to get very nervous, this is a big ... scheduled for ascending aorta, root and bav replace, vsd repair and 2 procedures to stop afib and arrhythmia. ... Brynn, I have also have aneurysm ascending aorta, leaking valve with afib, and was told there was a procedure to address the ...
The paired dorsal aorta is the first recognizable vessels in the embryo. These bilaterally positioned vessels are fused at the ... axial level, during the first four weeks of gestation in humans, to form a single midline dorsal aorta. ...
"https://ml.wiktionary.org/w/index.php?title=aorta&oldid=496209" എന്ന താളിൽനിന്ന് ശേഖരിച്ചത് ...
... aorta * * * noun : the part of the aorta from the arch to its bifurcation that passes downward in the thoracic and abdominal ... noun the descending part of the aorta that branches into the thoracic and abdominal aortae • Hypernyms: ↑ ... aorta - n.; pl. aortae or aortas the main artery of the body, from which all others derive. It arises from the left ventricle ( ... Descending aorta - The descending aorta is the part of the aorta, the largest artery in the body, that runs down through the ...
... in an aorta diseased by arteriosclerosis, a tear de-velops in the intima or the media degenerates, resulting in a dis-section . ... Occasionally, in an aorta diseased by arteriosclerosis, a tear de-velops in the intima or the media degenerates, resulting in a ... Occasionally, in an aorta diseased by arteriosclerosis, a tear de-velops in the intima or the media degenerates, resulting in a ... As the separation progresses, the arteries branching from the in-volved area of the aorta shear and occlude. The tear occurs ...
... ryšiai: platesnis terminas - kraujagyslių ydos ... liekamoji dešinioji aorta statusas T sritis gyvūnų raida, augimas, ontogenezė, embriologija atitikmenys: lot. ... liekamoji dešinioji aorta statusas T sritis gyvūnų raida, augimas, ontogenezė, embriologija atitikmenys: lot. Aorta dextra ... liekamoji dešinioji aorta - statusas T sritis gyvūnų raida, augimas, ontogenezė, embriologija atitikmenys: lot. Aorta dextra ...
Fetal ascending aorta Ascending aorta Ascending aorta Ascending aorta Ascending aorta Ascending aorta Ascending aorta Ascending ... The ascending aorta (AAo) is a portion of the aorta commencing at the upper part of the base of the left ventricle, on a level ... The sinotubular junction is the point in the ascending aorta where the aortic sinuses end and the aorta becomes a tubular ... This dilatation is termed the bulb of the aorta, and on transverse section presents a somewhat oval figure. The ascending aorta ...
An overriding aorta is a congenital heart defect where the aorta is positioned directly over a ventricular septal defect (VSD ... The result is that the aorta receives some blood from the right ventricle, causing mixing of oxygenated and deoxygenated blood ...
Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, ... The severity of coarctation of the aorta can be rated by a combination of the smallest aortic cross-sectional area of the aorta ... Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood ... The characteristic bulging of the sign is caused by dilatation of the aorta due to an indrawing of the aortic wall at the site ...
... that persons aorta (the major blood vessel that carries blood away from the heart to the body) is narrowed at some point. ... What Is Coarctation of the Aorta?. The aorta (pronounced: ay-OR-tuh) is the major artery that carries blood away from the heart ... Coarctation of the aorta can be repaired in several ways. Surgery can very effectively repair a narrowing of the aorta, usually ... When someone has coarctation (pronounced: ko-ark-TAY-shun) of the aorta, that persons aorta is narrowed at some point. ...
... aorta: In the abdominal cavity the aorta gives off a number of branches, which form an extensive network supplying blood to the ... In aorta. In the abdominal cavity the aorta gives off a number of branches, which form an extensive network supplying blood to ... Other articles where Abdominal aorta is discussed: ...
Coarctation of AortaPathophysiology• Narrowed aorta produces increased leftventricular afterload and wall stress, ... Thoracic aortic aneurysm• Descending aorta , ascending aorta• Cystic media degeneration: weakening aorticwall (elastic fiber ... Diseases of the aorta * 1. 30thApril 2010Dr. Fateh Ali Tipoo SultanFCPS (Med), FCPS (Card)Diplomate Certification Board of ... Coarctation of AortaIndications for operation1. Reduction of luminal diameter greaterthan 50% at any age2. Upper body ...
Aorta er hovedpulsåren hos dyr, særlig pattedyr. Aorta fører blod fra venstre hjertekammer ut i kroppen. Aorta hos andre dyr er ... aorta · brachiocephalica/innominata · bronchialis · thoracic (thoracis lateralis, thoracica interna) · subclavia · vertebralis ... Hos dyr med åpent blodsystem er ofte aorta den eneste tydelige delen av bodåresystemet. ... Hentet fra «https://no.wikipedia.org/w/index.php?title=Aorta&oldid=17869363» ...
Om dit probleem van overschotten en tekorten te voorkomen, is er het zogenoemde AORTA-model. Dit model is in dit hoofdstuk ... Berrevoets L., Berden B., van den Brink G. (2016) Berekend opleiden (AORTA-model). In: Berden B., Berrevoets L., Winasti W. ( ...
The close proximity of the esophagus to the thoracic aorta provides an excellent imaging opportunity. Transesophageal ... Thoracic aorta Aortic dissection Aortic aneurysm Atheromatous disease Plaque Blunt aortic trauma ... Maus T.M. (2016) Thoracic Aorta. In: Maus T., Nhieu S., Herway S. (eds) Essential Echocardiography. Springer, Cham. * First ... Midesophageal view of ascending aorta developed by a slow withdrawal of the probe from an aortic valve short axis (M4V 641 KB) ...
The descending aorta is broken down into two sections - the thoracic aorta and abdominal aorta - named after the body cavities ... Continued From Above... section of the aorta is known as the ascending aorta. The ascending aorta branches into the left and ... Aorta. At about one inch in diameter and traveling almost the entire length of the trunk, the aorta is the largest artery in ... Thus, the aorta provides oxygenated blood flow to all of the tissues of the body. The wall of the aorta is very thick and ...
... a chronic inflammation of the aorta. Takayasu disease symptoms include dizziness, headaches, chest pain, and abdominal pain. ... The inflammation of the aorta and its branch arteries can lead to poor blood supply to tissues of the body in patients with ... Some researchers have found that the prognosis is worse when the retinas of the eyes are affected, if the aorta is damaged, or ... Abdominal aortic aneurysm is a ballooning or widening of the main artery (the aorta) as it courses down through the abdomen. ...
... is narrowing of the aorta, the main artery that delivers oxygen-rich blood from the heart, around the ... Coarctation of the aorta is narrowing of the aorta, the main artery that delivers oxygen-rich blood from the heart, around the ... Coarctation of the aorta can increase blood pressure in the head and arms and lower blood pressure in the legs, as well as ... Symptoms of coarctation of the aorta depend on how narrowed the artery is and therefore how much blood can flow through it. If ...
If part of the aorta is narrowed, it is hard for blood to pass through the artery. This is called coarctation of the ... The aorta carries blood from the heart to the vessels that supply the body with blood. ... The aorta carries blood from the heart to the vessels that supply the body with blood. If part of the aorta is narrowed, it is ... The exact cause of coarctation of the aorta is unknown. It results from abnormalities in development of the aorta prior to ...
Aorta definition is - the great arterial trunk that carries blood from the heart to be distributed by branch arteries through ... Share aorta Post the Definition of aorta to Facebook Share the Definition of aorta on Twitter ... Britannica.com: Encyclopedia article about aorta. Comments on aorta What made you want to look up aorta? Please tell us where ... More from Merriam-Webster on aorta Spanish Central: Translation of aorta Nglish: Translation of aorta for Spanish Speakers ...
... of a short section of that portion of the aorta that arches over the heart. The aorta is the principal artery conducting blood ... Coarctation of the aorta, congenital malformation involving the constriction, or narrowing, ... cardiovascular disease: Coarctation of the aorta. Coarctation of the aorta, which is a constriction of the aorta, usually in ... aorta. Aorta. , in vertebrates and some invertebrates, the blood vessel (or vessels) carrying blood from the heart to all the ...
Coarctation of the aorta is a birth defect in which a part of the aorta is narrower than usual. To learn what its like to live ... Coarctation of the aorta is a narrowing of part of the aorta (the major artery that supplies oxygenated blood to the entire ... Nicholas was born with a serious heart defect called critical coarctation of the aorta, a severe narrowing in his aorta cutting ... Nicholas was born with a critical congenital heart defect (critical CHD) called coarctation of the aorta. Read his ...
... the portion of the aorta between the diaphragm and the bifurcation into the right and left common iliac arteries. ... Share abdominal aorta Post the Definition of abdominal aorta to Facebook Share the Definition of abdominal aorta on Twitter ... Dictionary Entries near abdominal aorta. abdom abdomen abdominal abdominal aorta abdominal cavity abdominal hernia abdominal ... Comments on abdominal aorta What made you want to look up abdominal aorta? Please tell us where you read or heard it (including ...
... in a statement that Ritter was rushed to the hospital after suffering from an unrecognized and undetected flaw in his aorta, ...
Subject: Aneurism of the aorta Category: Health Asked by: bob2-ga List Price: $5.00. Posted: 16 Aug 2002 03:12 PDT Expires: 15 ... Subject: Re: Aneurism of the aorta Answered By: alienintelligence-ga on 16 Aug 2002 05:33 PDT ... Can an aneurism of a rupture of the aorta be caused by alcoholism?. ... The stress of hypertension or high blood pressure to the wall of the aorta over many years can lead to enlargement of the blood ...
Learn about the heart birth defect Coarctation of the Aorta. ... What is Coarctation of the Aorta?. Coarctation of the aorta is ... If the aorta is not widened, the heart may weaken enough that it leads to heart failure. Coarctation of the aorta often occurs ... Coarctation (pronounced koh-ark-TEY-shun) of the aorta is a birth defect in which a part of the aorta, the tube that carries ... The stent is used more often to initially widen the aorta or re-widen it if the aorta narrows again after surgery has been ...
Signs and symptoms of coarctation of the aorta may appear soon after birth in severe cases or not until later in childhood in ... What is coarctation of the aorta? The aorta is the main blood vessel that comes from the heart and supplies blood to the entire ... Symptoms of Coarctation of the Aorta. Symptoms of coarctation of the aorta develop because the upper parts of the body get too ... Coarctation (pronounced koh-ark-TAY-shun) of the aorta is a condition where the aorta has a very narrow area, making it shaped ...
... is obstruction or narrowing of the aorta that typically occurs just beyond ... Even when repaired in childhood, ongoing follow-up as an adult is required to screen for abnormal growth of the aorta, re- ...
... the aorta then travels inferiorly as the descending aorta. The descending aorta has two parts. The aorta begins to descend in ... Ascending aortaEdit. Main article: Ascending aorta. The ascending aorta begins at the opening of the aortic valve in the left ... Abdominal aortaEdit. Main article: Abdominal aorta. The abdominal aorta begins at the aortic hiatus of the diaphragm at the ... Thoracic aortaEdit. Main article: Descending thoracic aorta. The thoracic descending aorta gives rise to the intercostal and ...
... and normal aortas from transplant donors, and dissected aortas from surgery for aortic dissection. These aortas underwent ... Biomechanics of Aortic Dissection: A Comparison of Aortas Associated With Bicuspid and Tricuspid Aortic Valves ... Aneurysmal ascending aortas were collected from elective aortic surgery, ...
Diseases of the aorta and trauma to the aorta and heart (2) ... A Patient-Specific Assessment of The Thoracic Aorta Pouya ...
Learn about its function and location as well as conditions that affect the aorta. ... WebMDs Aorta Anatomy Page provides a detailed image and definition of the aorta. ... The aorta is the largest artery in the body. The aorta begins at the top of the left ventricle, the hearts muscular pumping ... The aorta is a tube about a foot long and just over an inch in diameter. The aorta is divided into four sections:. • The ...
... is a narrowing of the aorta, the major blood vessel that carries blood away from the heart to the body. ... What Is Coarctation of the Aorta?. Coarctation of the aorta (COA) is a narrowing of the aorta, the major blood vessel that ... Coarctation of the aorta can be repaired with surgery or other procedures. One of the most common ways to fix a coarctation is ... Coarctation of the aorta is a congenital defect, meaning that a baby is born with it. Doctors arent sure why some people ...
  • (3 days ago) Why is a cta abdominal aorta and bilateral iliofemoral runoff performed? (couponrecords.com)
  • (8 days ago) CTA of abdominal aorta and bilateral iliofemoral lower extremity runoff, with contrast, including noncontrast images and image postprocessing. (couponrecords.com)
  • CT scan of abdominal aorta and both leg arteries with contrast. (couponrecords.com)
  • CTA of abdominal aorta and bilateral iliofemoral lower extremity runoff, with contrast. (couponrecords.com)
  • To evaluate run-off computed tomography angiography (CTA) of abdominal aorta and lower extremities for detecting musculoskeletal pathologies and clinically relevant extravascular incidental findings in patients with intermittent claudication (IC) and suspected peripheral arterial disease (PAD). (couponrecords.com)
  • The aorta is the main artery in the body, carrying blood from the heart and down through the abdomen before splitting off into smaller arteries. (medicalnewstoday.com)
  • As the separation progresses, the arteries branching from the in-volved area of the aorta shear and occlude. (brainkart.com)
  • The dissec-tion of the aorta may progress backward in the direction of the heart, obstructing the openings to the coronary arteries or produc-ing hemopericardium (effusion of blood into the pericardial sac) or aortic insufficiency, or it may extend in the opposite direction, causing occlusion of the arteries supplying the gastrointestinal tract, kidneys, spinal cord, and legs. (brainkart.com)
  • Descending aorta - The descending aorta is the part of the aorta, the largest artery in the body, that runs down through the chest and the abdomen. (enacademic.com)
  • An aortic dissection is a tear in the wall of the aorta. (phaa.com)
  • The blood under high pressure may then enter the wall of the aorta and create a channel for the blood between the inner and middle layer. (phaa.com)
  • Another factor is that wall of the aorta may be weakened. (phaa.com)
  • Saya (56 tahun) didiagnosis dokter mengidap penyakit aneurisma aorta bagian abdomen. (trubus-online.co.id)
  • Penyakit Aneurisma Aorta - Aneurisma aorta atau aneurisme aorta merupakan pembengkakan pembuluh aorta perut atau pembesaran aorta, pembuluh darah utama yang menyalurkan darah ke tubuh pada level abdomen. (halosehat.co.id)
  • A rupture may occur through adventitia or into the lumen through the intima, allow-ing blood to reenter the main channel and resulting in chronic dissection or occlusion of branches of the aorta. (brainkart.com)
  • The aorta is the large artery that carries this blood from the heart and distributes it throughout the body via various branches. (phaa.com)
  • In experimental atherosclerosis the aorta supports CD4+ T cell activation selectively driving Th1 polarization. (ox.ac.uk)
  • Brynn, I have also have aneurysm ascending aorta, leaking valve with afib, and was told there was a procedure to address the afib when the repairs were made. (valvereplacement.org)
  • A patient with a dissecting aorta requires the same nursing care as a patient with an aortic aneurysm requiring surgical intervention, as described earlier. (brainkart.com)
  • According to a study in older adults, memory performance as we age may be associated with the flexibility of the largest artery in our body: the aorta. (medicalnewstoday.com)
  • The paired dorsal aorta is the first recognizable vessels in the embryo. (lifemapsc.com)
  • These bilaterally positioned vessels are fused at the axial level, during the first four weeks of gestation in humans, to form a single midline dorsal aorta. (lifemapsc.com)
  • I was told I had a 3.2 dilation ascending aorta and to follow up with a doctor. (mayoclinic.org)
  • pl. aortae or aortas the main artery of the body, from which all others derive. (enacademic.com)
  • I was diagnosed in 2012 with ascending aorta dialation of 4.1 cm. (mayoclinic.org)
  • I don't know what's going on I myself was told i Have a ascending aorta was 3.3 from a ct scan with contrast. (mayoclinic.org)
  • Most aortic dissections occur in the part of the aorta that arises from the heart which is known as the ascending aorta. (phaa.com)
  • Type A , which is a tear in the ascending aorta. (phaa.com)
  • He did mention something about ask the doctor if you can "preserve the aorta":By that he means keep your old aorta and not replace with a pig tissue. (mayoclinic.org)
  • descending aorta - (Order Mysida): Major unpaired blood vessel arising ventrally near posterior end of heart. (enacademic.com)
  • Type B , which is a tear in the descending aorta. (phaa.com)
  • Why blood entering the aorta from the reservoir flows into the heart? (proprofs.com)
  • As previously mentioned, the signs and symptoms of a tear in the aorta may be similar to several other heart conditions. (phaa.com)
  • Methods and Results - Here we have identified naïve T cells in the aorta of wild-type and TCR transgenic mice and we demonstrate that naïve T cells can be primed directly in the vessel wall with a similar activation profile to splenic and lymphoid T cells. (ox.ac.uk)
  • Conclusions - Our results demonstrate that the aorta can support T cell priming and that naïve T cells traffic between the circulation and vessel wall. (ox.ac.uk)
  • (7 days ago) Doctors give unbiased, helpful information on indications, contra-indications, benefits, and complications: Dr. Fisher on cta aorta and bilateral iliofemoral runoff: Usually to evaluate for leg pain with a suspected vascular etiology. (couponrecords.com)
  • A healthier, more elastic aorta is also theorized to protect cognitive function by reducing the negative effects of excessive blood pressure on the brain. (medicalnewstoday.com)
  • The team wanted to see whether a more elastic aorta would mean better memory performance in older adults. (medicalnewstoday.com)
  • The instructions for use (IFU) are not a clinical guideline, so trainees should really think about what the main considerations are when they are implanting devices in the aorta to create a durable repair," said Tara Mastracci (Royal Free Hospital, London, UK) at the London Aortic Symposium 2018 . (blearning.net)
  • There are various diseases of the aorta but one of the more serious is an aortic dissection. (phaa.com)
  • Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. (wikipedia.org)
  • Preductal coarctation results when an intracardiac anomaly during fetal life decreases blood flow through the left side of the heart, leading to hypoplastic development of the aorta. (wikipedia.org)
  • Postductal coarctation is most likely the result of the extension of a muscular artery (ductus arteriosus) into an elastic artery (aorta) during fetal life, where the contraction and fibrosis of the ductus arteriosus upon birth subsequently narrows the aortic lumen. (wikipedia.org)
  • Some children born with coarctation of the aorta have other heart defects too, such as aortic stenosis, ventricular septal defect, patent ductus arteriosus or mitral valve abnormalities. (wikipedia.org)
  • When someone has coarctation (pronounced: ko-ark-TAY-shun) of the aorta , that person's aorta is narrowed at some point. (kidshealth.org)
  • A coarctation can affect the body's blood circulation because the left side of the heart has to work harder to pump blood through the narrowed aorta. (kidshealth.org)
  • A coarctation can happen anywhere in the aorta, but most often is found just beyond the point where the arteries that carry the blood to the upper body and head branch off from the aorta. (kidshealth.org)
  • Coarctation of the aorta, COA for short, is a congenital defect, meaning that someone is born with it. (kidshealth.org)
  • How Is Coarctation of the Aorta Diagnosed? (kidshealth.org)
  • How Is Coarctation of the Aorta Treated? (kidshealth.org)
  • Coarctation of the aorta can be repaired in several ways. (kidshealth.org)
  • Coarctation of the aorta is narrowing of the aorta, the main artery that delivers oxygen-rich blood from the heart, around the body. (news-medical.net)
  • Coarctation of the aorta can increase blood pressure in the head and arms and lower blood pressure in the legs, as well as place a great amount of strain on the heart. (news-medical.net)
  • In rare cases, coarctation of the aorta develops later in life. (news-medical.net)
  • Symptoms of coarctation of the aorta depend on how narrowed the artery is and therefore how much blood can flow through it. (news-medical.net)
  • If coarctation of the aorta is not treated, people usually die before the age of 40 and surgery is therefore usually recommended before the age of 10. (news-medical.net)
  • Retrieved on November 29, 2020 from https://www.news-medical.net/health/Coarctation-of-the-Aorta.aspx. (news-medical.net)
  • This is called coarctation of the aorta. (medlineplus.gov)
  • The exact cause of coarctation of the aorta is unknown. (medlineplus.gov)
  • Coarctation of the aorta can be cured with surgery. (medlineplus.gov)
  • Coarctation of the aorta , congenital malformation involving the constriction, or narrowing, of a short section of that portion of the aorta that arches over the heart . (britannica.com)
  • Coarctation of the aorta is a birth defect in which a part of the aorta is narrower than usual. (cdc.gov)
  • To learn what it's like to live with this condition or how families are affected, read these real stories from people living with coarctation of the aorta. (cdc.gov)
  • Nicholas was born with a serious heart defect called critical coarctation of th e aorta , a severe narrowing in his aorta cutting off blood flow to the lower half of his body. (cdc.gov)
  • coarctation of the aorta and bicuspid aortic valve. (cdc.gov)
  • Coarctation of the aorta is a narrowing of part of the aorta (the major artery that supplies oxygenated blood to the entire body). (cdc.gov)
  • Coarctation (pronounced koh-ark-TEY-shun) of the aorta is a birth defect in which a part of the aorta, the tube that carries oxygen-rich blood to the body, is narrower than usual. (cdc.gov)
  • For this reason, coarctation of the aorta is often considered a critical congenital heart defect . (cdc.gov)
  • In some babies with coarctation, it is thought that some tissue from the wall of ductus arteriosus blends into the tissue of the aorta. (cdc.gov)
  • Since the narrowing of the aorta is usually located after arteries branch to the upper body, coarctation in this region can lead to normal or high blood pressure and pulsing of blood in the head and arms and low blood pressure and weak pulses in the legs and lower body. (cdc.gov)
  • Coarctation of the aorta often occurs with other congenital heart defects. (cdc.gov)
  • In a 2019 study, using 2010-2014 data from 39 population-based birth defects surveillance programs, the Centers for Disease Control and Prevention (CDC) estimated that about 4 of every 10,000 babies born had coarctation of the aorta. (cdc.gov)
  • This means about 2,200 babies are born each year in the United States with coarctation of the aorta. (cdc.gov)
  • In other words, about 1 in every 1,800 babies born in the United States each year are born with coarctation of the aorta. (cdc.gov)
  • Nicholas was born with coarctation of the aorta. (cdc.gov)
  • The causes of heart defects, including coarctation of the aorta, among most babies are unknown. (cdc.gov)
  • Heart defects, like coarctation of the aorta, are also thought to be caused by a combination of genes and other risk factors, such as things the mother comes in contact with in the environment, what the mother eats or drinks, or medicines the mother uses. (cdc.gov)
  • Coarctation of the aorta is usually diagnosed after the baby is born. (cdc.gov)
  • Newborn screening using pulse oximetry during the first few days of life may or may not detect coarctation of the aorta. (cdc.gov)
  • Older children and adults with coarctation of the aorta often have high blood pressure in the arms. (cdc.gov)
  • Coarctation (pronounced koh-ark-TAY-shun) of the aorta is a condition where the aorta has a very narrow area, making it shaped like an hourglass. (seattlechildrens.org)
  • Our heart team has treated many children with coarctation of the aorta. (seattlechildrens.org)
  • Coarctation of the aorta is obstruction or narrowing of the aorta that typically occurs just beyond the left subclavian artery (the artery that supplies blood to the left arm). (emoryhealthcare.org)
  • Coarctation of the aorta: Narrowing of the aorta between its branches to the arms and those to the legs. (webmd.com)
  • Coarctation of the aorta (CoA) is a relatively common defect that accounts for 5-8% of all congenital heart defects. (medscape.com)
  • Coarctation of the aorta may occur as an isolated defect or in association with various other lesions, most commonly bicuspid aortic valve and ventricular septal defect (VSD). (medscape.com)
  • The diagnosis of coarctation of the aorta may be missed unless an index of suspicion is maintained, and diagnosis is often delayed until the patient develops congestive heart failure (CHF) , which is common in infants, or hypertension , which is common in older children. (medscape.com)
  • This article discusses the pathology, pathophysiology, clinical features, noninvasive and invasive evaluation, and therapy in patients with coarctation of the aorta. (medscape.com)
  • Coarctation of the aorta may be defined as a constricted aortic segment that comprises localized medial thickening, with some infolding of the medial and superimposed neointimal tissue. (medscape.com)
  • In the past, coarctation of the aorta has been described as preductal (or infantile) type or postductal (or adult) type, depending on whether the coarctation segment is proximal or distal to the ductus arteriosus, respectively. (medscape.com)
  • The classic coarctation of the aorta is located in the thoracic aorta distal to the origin of the left subclavian artery at about the level of the ductal structure. (medscape.com)
  • Dilatation of the descending aorta immediately distal to the coarctation segment (poststenotic dilatation) is usually present. (medscape.com)
  • A jet lesion on the wall of the aorta distal to the coarctation site may also be present. (medscape.com)
  • Bicuspid aortic valve may be seen in nearly two thirds of infants with coarctation of the aorta, whereas only 30% of those who present in childhood have such an anomaly. (medscape.com)
  • Mitral valve anomalies, although less common than those of the aortic valve, are also associated with coarctation of the aorta. (medscape.com)
  • Sometimes, coarctation of the aorta is a complicating feature of a more complex cyanotic heart defect, such as transposition of the great arteries , Taussig-Bing anomaly, double-inlet left ventricle, tricuspid atresia with transposition of the great arteries, and hypoplastic left heart syndrome . (medscape.com)
  • Some patients with coarctation of the aorta may have cerebral aneurysms, predisposing them to cerebrovascular accidents with severe hypertension later in life. (medscape.com)
  • Coarctation of the aorta is the most common cardiac defect associated with Turner syndrome . (medscape.com)
  • When someone has coarctation of the aorta, the aorta is narrowed at some point. (rchsd.org)
  • Any person diagnosed with high blood pressure should be checked for coarctation of the aorta. (rchsd.org)
  • Coarctation of the aorta can be repaired either by surgery or other procedures. (rchsd.org)
  • It turned out Heather had a heart condition known as coarctation of the aorta. (rchsd.org)
  • Coarctation of the aorta is a narrowing of the descending aorta, which is typically located at the insertion of the ductus arteriosus just distal to the left subclavian artery ( figure 1 ). (uptodate.com)
  • The clinical manifestations and diagnosis of coarctation of the aorta will be reviewed here. (uptodate.com)
  • See 'Management of coarctation of the aorta' . (uptodate.com)
  • Coarctation of the aorta accounts for 4 to 6 percent of all congenital heart defects with a reported prevalence of approximately 4 per 10,000 live births [ 1,2 ]. (uptodate.com)
  • Although there are acquired causes, the etiology of coarctation of the aorta is generally congenital. (uptodate.com)
  • Mayo Clinic doctors trained in heart conditions ( cardiologists ), doctors trained in treating children with heart conditions ( pediatric cardiologists ) and heart surgeons ( cardiovascular surgeons ) have extensive experience diagnosing and treating people with coarctation of the aorta and other congenital heart diseases. (mayoclinic.org)
  • Doctors trained and experienced in treating adults with coarctation of the aorta and other congenital heart diseases treat people at Mayo Clinic's campuses in Arizona, Florida and Minnesota. (mayoclinic.org)
  • Doctors with expertise and training in coarctation of the aorta and other congenital heart diseases treat adults and children in the Center for Congenital Heart Disease at Mayo Clinic's campus in Minnesota. (mayoclinic.org)
  • Mayo Clinic doctors have been performing surgery to treat coarctation of the aorta since 1946. (mayoclinic.org)
  • Mayo Clinic doctors have expertise in treating coarctation of the aorta with surgical repair and balloon angioplasty. (mayoclinic.org)
  • Their commitment to research means you may able to participate in clinical trials to advance the diagnosis and treatment of coarctation of the aorta. (mayoclinic.org)
  • Treatment for coarctation of the aorta can involve medical devices and surgery. (mayoclinic.org)
  • Mayo Clinic staff actively conducts research in causes, diagnostic tests and treatments for coarctation of the aorta, and participates in clinical trials. (mayoclinic.org)
  • Mayo Clinic doctors have extensive experience and expertise in diagnosing and treating people with all types of heart conditions, including coarctation of the aorta. (mayoclinic.org)
  • Mayo doctors evaluate and treat more than 300 people with coarctation of the aorta each year. (mayoclinic.org)
  • Coarctation of the aorta is a rare congenital abnormality in which the aorta, a large major blood vessel that delivers oxygen rich blood to the body, is narrowed. (patientslikeme.com)
  • When you share what it's like to have coarctation of the aorta through your profile, those stories and data appear here too. (patientslikeme.com)
  • Got a question about living with coarctation of the aorta? (patientslikeme.com)
  • Who has coarctation of the aorta on PatientsLikeMe? (patientslikeme.com)
  • Coarctation is a narrowing or pinching in the aorta, usually between the aortic arch and descending aorta. (childrensmn.org)
  • Coarctation of the aorta (also called aortic coarctation) forces your baby's heart to pump harder in order to push blood through the constricted part of the aorta. (childrensmn.org)
  • What causes coarctation of the aorta? (childrensmn.org)
  • Coarctation of the aorta occurs during the first eight weeks of fetal development, when the heart is forming. (childrensmn.org)
  • Coarctation of the aorta makes up about 8-11% of all congenital heart defects . (childrensmn.org)
  • Coarctation of the aorta often appears alongside other heart defects. (childrensmn.org)
  • Coarctation of the aorta is a congenital (present at birth) heart defect involving a narrowing of the aorta. (choc.org)
  • The narrowed segment called coarctation can occur anywhere in the aorta, but is most likely to happen in the segment just after the aortic arch. (choc.org)
  • About one-third of children with coarctation of the aorta also have a bicuspid aortic valve-a valve that has two leaflets instead of the usual three. (choc.org)
  • Coarctation of the aorta occurs in a small percentage of children with congenital heart disease. (choc.org)
  • The following are the most common symptoms of coarctation of the aorta. (choc.org)
  • The symptoms of coarctation of the aorta may resemble other medical conditions or heart problems. (choc.org)
  • A heart murmur is simply a noise caused by the turbulence of blood flowing through the obstruction in the coarctation segment of the aorta. (choc.org)
  • Coarctation of the aorta is a common heart defect present at birth. (healthwise.net)
  • Coarctation of the aorta makes it harder for the heart to pump blood to the body. (healthwise.net)
  • Coarctation of the aorta requires repair by surgery or heart catheterization. (healthwise.net)
  • Coarctation of the aorta is a narrowing of the aorta, the main artery that delivers oxygen-rich (red) blood to the body. (childrenshospital.org)
  • Coarctation of the aorta occurs in about 6 to 8 percent of all children with congenital heart disease, and twice as frequently in boys. (childrenshospital.org)
  • Seventy-five percent of children with coarctation of the aorta also have a bicuspid aortic valve, in which the aortic valve has two leaflets, instead of the usual three. (childrenshospital.org)
  • Boston Children's Hospital has vast experience treating infants and children who have coarctation of the aorta. (childrenshospital.org)
  • Surgical repair of aorta may be required for aortic aneurysms, aortic dissections or congenital malformations such as coarctation. (edu.au)
  • That's why Nemours pediatric heart experts specialize in early detection and repair of congenital heart defects, such as coarctation of the aorta. (nemours.org)
  • If your child's been diagnosed with coarctation of the aorta or a narrowing of the aorta, we're here to ease your concerns, answer your questions, and give your child the best possible chance for a healthy future. (nemours.org)
  • Sometimes children with coarctation of the aorta can also have a ventricular septal defect , a hole between the lower chambers of the heart, or a bicuspid aortic valve, which means the valve has two flaps instead of three. (chop.edu)
  • In severe cases, coarctation of the aorta symptoms will appear within the first few days of life. (chop.edu)
  • If the narrowing is mild, coarctation of the aorta symptoms may go unnoticed until the child is older or even an adult. (chop.edu)
  • If your infant has severe coarctation of the aorta, in most cases a doctor in the birth hospital will notice symptoms. (chop.edu)
  • Milder cases of coarctation of the aorta sometimes aren't diagnosed until the child is older. (chop.edu)
  • What are the treatment options for coarctation of the aorta? (chop.edu)
  • Coarctation of the aorta may require either cardiac catheterization or open heart surgery, depending on the severity of the narrowing and on other factors such as your child's age and overall health. (chop.edu)
  • Because of enormous strides in medicine and technology, most children born with coarctation of the aorta go on to lead productive lives as adults. (chop.edu)
  • What is the follow-up care for coarctation of the aorta? (chop.edu)
  • Most children who have repair of coarctation of the aorta recover completely and won't require additional procedures. (chop.edu)
  • Coarctation of the aorta is a congenital defect, meaning that a baby is born with it. (akronchildrens.org)
  • Coarctation of the aorta can be repaired with surgery or other procedures. (akronchildrens.org)
  • Coarctation of the aorta is a type of congenital heart defect. (healthlinkbc.ca)
  • He had a history of thoracic aorta replacement, which was performed 30 years ago because of a coarctation of the descending aorta. (lww.com)
  • The ascending aorta (AAo) is a portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum. (wikipedia.org)
  • The aortic root is the portion of the aorta beginning at the aortic annulus and extending to the sinotubular junction. (wikipedia.org)
  • One way of classifying a part of the aorta is by anatomical compartment, where the thoracic aorta (or thoracic portion of the aorta) runs from the heart to the diaphragm . (wikipedia.org)
  • The aorta then continues downward as the abdominal aorta (or abdominal portion of the aorta) diaphragm to the aortic bifurcation . (wikipedia.org)
  • Gore & Associates) was deployed in the infrarenal abdominal aorta extending from the origin of the IMA to the terminal portion of the aorta approximately 1 cm superior to the aortic bifurcation. (thefreedictionary.com)
  • This portion of the aorta is also a favorite seat of aneurism. (chestofbooks.com)
  • section of the aorta is known as the ascending aorta. (innerbody.com)
  • In children and adolescents the narrow section of the aorta is removed, and the two free ends are sewn together. (britannica.com)
  • Surgery to repair or replace the injured section of the aorta. (heart.org)
  • Surgeons can remove the narrowed section of the aorta and then sew the ends of the aorta back together, or they can enlarge the aorta with a patch. (chop.edu)
  • Then, using the catheter, the cardiologist can inflate the balloon in the narrowed section of the aorta to stretch it. (chop.edu)
  • Small aneurysms can be patched, but large aneurysms can lead to a potentially deadly tearing of the aorta known as an aortic dissection. (innerbody.com)
  • Aneurysms of the thoracic aorta (see Figure 1 ) are not as common as those affecting the abdominal portion, but carry a higher risk of rupture. (nih.gov)
  • The results of this study showed that the majority of mycotic aneurysms caused by Salmonella were in the abdominal aorta (37/57), and some patients present diarrhea when infected with Salmonella. (thefreedictionary.com)
  • Thoracic aortic aneurysms (TAAs) involve the ascending aorta most commonly (50%), followed by the descending aorta (40%), whereas arch aneurysms (10%) and thoraco-abdominal aneurysms (10%) occur less often. (bmj.com)
  • The system previously had FDA indication for treatment of aneurysms and penetrating ulcers of the descending thoracic aorta. (medgadget.com)
  • Aneurysms and dissections of the aorta are life-threatening conditions and should be treated as a medical emergency. (heart.org)
  • False aneurysms of the abdominal aorta are usually due to trauma or infection. (unboundmedicine.com)
  • A team of researchers at Baylor College of Medicine, the Texas Heart Institute and Baylor College of Medicine's Cardiovascular Research Institute has found that ciprofloxacin, a widely prescribed antibiotic, increases the risk of tears and rupture on the main artery of the body, the aorta, in a mouse model of human aortic aneurysms and dissections (AAD), a disease that carries high risk of death from aortic rupture. (bcm.edu)
  • They found that patients who received fluoroquinolones had a higher risk for aneurysms (formation of balloon-like areas in the aorta that weaken the integrity of the vessel), ruptures or dissections (tears in the wall) than patients who did not receive the antibiotics. (bcm.edu)
  • People at increased risk include those with a history of blockages or aneurysms (abnormal bulges) of the aorta or other blood vessels, high blood pressure, certain genetic disorders that involve blood vessel changes, and the elderly. (raps.org)
  • Surgery can very effectively repair a narrowing of the aorta, usually by removing the narrow section and reconnecting the two good ends of the aorta. (kidshealth.org)
  • If the problem area is small, the two free ends of the aorta may be reconnected. (medlineplus.gov)
  • Different types of surgery can repair a narrowing of the aorta, but one of the most common ways to fix COA is to remove the narrow section and reconnect the two ends of the aorta. (rchsd.org)
  • This is the leading predisposing factor for the development of aneurysm of the thoracic aorta' FAQ on alcoholism [ http://www.niaaa.nih.gov/faq/faq.htm ] Now, as far as your question: Can an aneurism of a rupture of the aorta be caused by alcoholism? (google.com)
  • A typical aneurysm of the thoracic aorta at surgery. (nih.gov)
  • The elastin-to-collagen ratio progressively decreases as the aorta traverses distally into the descending thoracic and abdominal aorta. (bmj.com)
  • It becomes the descending (thoracic and abdominal) aortae and median sacral artery. (thefreedictionary.com)
  • A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. (google.co.uk)
  • The present invention is directed to methods and devices for occluding a patient's ascending aorta and maintaining circulation of oxygenated blood in the patient when the patient's heart is arrested. (google.co.uk)
  • Another device and method for occluding a patient's ascending aorta is described in Re. (google.co.uk)
  • We present this interesting case because retroperitoneal fibrosis encircling the abdominal aorta can mimic abdominal aorta aneurysm radiologically. (hindawi.com)
  • At the union of the ascending aorta with the aortic arch the caliber of the vessel is increased, owing to a bulging of its right wall. (wikipedia.org)
  • The arch of the aorta, and its branches. (wikipedia.org)
  • In this system, the aorta starts as the ascending aorta then travels superiorly from the heart and then makes a hairpin turn known as the aortic arch . (wikipedia.org)
  • Following the aortic arch, the aorta then travels inferiorly as the descending aorta. (wikipedia.org)
  • : 191,204 The transition from ascending aorta to aortic arch is at the pericardial reflection on the aorta. (wikipedia.org)
  • It has four main sections: the ascending aorta, the aortic arch, the descending thoracic aorta and the abdominal aorta. (reference.com)
  • The aortic arch curves like a cane and connects the ascending aorta and descending aorta. (reference.com)
  • The descending aorta is a continuation of the aortic arch and is divided into the two sections: the thoracic aorta and the abdominal aorta. (reference.com)
  • The part of the aorta that extends from its origin in the left ventricle of the heart to the aortic arch. (thefreedictionary.com)
  • The ductus arteriosus at birth is about 1 cm. long and runs from the pulmonary artery to the arch of the aorta below the left subclavian artery. (chestofbooks.com)
  • When, after birth, the lungs are used the ductus arteriosus becomes obliterated and is found later in life as a cord running to the under side of the arch of the aorta. (chestofbooks.com)
  • The great amount of distress which these aneurisms of the arch of the aorta may give rise to is readily appreciated when one recalls that there is only a distance of 5 or 6 cm. (2 1/4 in. (chestofbooks.com)
  • The descending aorta begins at the arch of the aorta (where it loops over the heart to begin its descent). (healthline.com)
  • The descending aorta (thoracic aorta) is between the arch of the aorta and the diaphragm muscle below the ribs. (healthline.com)
  • The aorta has three segments: Ascending aorta, transverse aortic arch, and descending aorta. (childrensmn.org)
  • When people aren't diagnosed until their teens, it's usually because the narrowing in the aorta is not severe enough to cause serious symptoms until then. (kidshealth.org)
  • Usually, in this case, the narrowing in the aorta is not severe enough to cause serious symptoms while the person is very young. (rchsd.org)
  • The more the aorta is narrowed, the more severe the symptoms will be. (chop.edu)
  • Can an aneurism of a rupture of the aorta be caused by alcoholism? (google.com)
  • The defect can also cause dissection or rupture of the aorta, which can be fatal in many people by the age of 40. (rchsd.org)
  • Aneurysmal disease of the aorta is clinically important since, as the diameter of the aorta expands, linear wall stress increases, which in turn directly increases the risk of spontaneous aortic rupture-an event with extremely poor prognosis for the patient. (bmj.com)
  • 1 Grafts may be introduced during open or endovascular procedures to prevent rupture of an expanding vascular aneurysm, usually in the abdominal aorta. (edu.au)
  • In mice with moderately stressed aortas that had received the placebo, 45 percent developed AAD, 24 percent developed aortic dissection and none had rupture. (bcm.edu)
  • On the other hand, 79 percent of the mice with moderately stressed aortas that received antibiotic developed AAD, 67 percent had aortic dissection, and 15 percent had fatal rupture. (bcm.edu)
  • It also can cause dissection or rupture of the aorta, which can be fatal. (akronchildrens.org)
  • Aortic Dissection can quickly lead to a painful and frightening death as a result of reduced blood flow to the heart or rupture of the aorta. (change.org)
  • There are several terms which are interchangeably used to describe injury to the aorta such as tear , laceration , transection , and rupture . (primidi.com)
  • There was no specific evidence of aortic aneurysm or dissection, therefore a spontaneous rupture of the ascending aorta was diagnosed. (umin.ac.jp)
  • The risk of rupture increases when the aneurysm is larger than about twice the normal diameter of a healthy aorta blood vessel. (clevelandclinic.org)
  • After the aorta passes through the diaphragm , it is known as the abdominal aorta. (wikipedia.org)
  • The thoracic aorta is called the abdominal aorta because it enters the abdominal cavity through the diaphragm and it lies at the posterior abdominal wall, anterior to the vertebral column. (thefreedictionary.com)
  • LOS ANGELES, Sept. 12 (UPI) -- Emmy-winning actor and comedian John Ritter died unexpectedly Friday after suffering what was described as a "dissection of the aorta. (upi.com)
  • Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood through the aorta to deliver blood to the lower part of the body. (wikipedia.org)
  • Because of this narrowing, the left ventricle of the heart must pump much harder than normal to move blood through the aorta to the lower body. (chop.edu)
  • This narrowing causes the left side of the heart to work harder to pump blood through the aorta. (akronchildrens.org)
  • It results from abnormalities in development of the aorta prior to birth. (medlineplus.gov)
  • An overriding aorta is a congenital heart defect where the aorta is positioned directly over a ventricular septal defect (VSD), instead of over the left ventricle. (wikipedia.org)
  • Michele Cohen Marill, Wired , "Ultra-Fast Genome Sequencing Could Save the Lives of Newborns," 9 Mar. 2020 An aortic dissection is when there is a tear in the inner layer of the aorta , a condition that most frequently occurs in men in their 60s and 70s, the Mayo Clinic website said. (merriam-webster.com)
  • CBS News , "JPMorgan CEO Jamie Dimon has emergency heart surgery," 6 Mar. 2020 An aortic dissection occurs when blood forces its way into a tear in the aorta , the biggest artery in the body, separating its layers or peeling them apart. (merriam-webster.com)
  • The defect occurs when a baby's aorta does not form correctly as the baby grows and develops during pregnancy. (cdc.gov)
  • When a problem occurs with the aorta, the heart and the entire body's blood supply can be jeopardized. (heart.org)
  • For all intents and purposes, the latter is used when a tear occurs across all or nearly all of the circumference of the aorta . (primidi.com)
  • The aorta (pronounced: ay-OR-tuh) is the major artery that carries blood away from the heart to the body. (kidshealth.org)
  • Other tests that produce images of the heart also might be done, such as a chest X-ray, a magnetic resonance imaging (MRI) test, or a computerized tomography (CT) scan to look for a narrowing of the aorta. (kidshealth.org)
  • The aorta carries all of the oxygenated blood exiting the heart in the systemic loop of the circulatory system. (innerbody.com)
  • Takayasu disease is a chronic inflammation of the large blood vessels that distribute blood from the heart, including the aorta and its main branches. (medicinenet.com)
  • However, there is an increased risk of heart problems when a person has had their aorta repaired and these individuals require careful life-long follow-up. (news-medical.net)
  • The aorta carries blood from the heart to the vessels that supply the body with blood. (medlineplus.gov)
  • However, there is an increased risk for death due to heart problems among those who have had their aorta repaired. (medlineplus.gov)
  • Doha Madani, NBC News , "JP Morgan Chase CEO Jamie Dimon recovering from emergency heart surgery," 6 Mar. 2020 That is when blood leaks through a tear in the inner layer of the aorta , the large artery that carries blood away from the heart to the rest of the body. (merriam-webster.com)
  • Emily Flitter, New York Times , "JPMorgan Chief Executive Jamie Dimon Has Emergency Heart Surgery," 5 Mar. 2020 His aorta tore like an old garden hose left out in the sun too long. (merriam-webster.com)
  • The aorta is the principal artery conducting blood from the heart into the systemic circulation . (britannica.com)
  • http://216.239.51.100/search?q=cache:5OJZlfSZSMMC:www.irishheart.ie/PRO/Considerations%2520in%2520BP%2520management.pdf+aneurysm+aorta+%22alcohol+related%22&hl=en&ie=UTF-8 ] The alcohol related pathogenesis or development of the diseased condition of cardiac damage is charaterized by occurance of both systolic and diastolic hypertension, arrhythmias and alcoholic cardiomyopathy or a condition where the heart muscle is weakened and cannot pump blood efficiently. (google.com)
  • If the aorta is not widened, the heart may weaken enough that it leads to heart failure . (cdc.gov)
  • The aorta is the main blood vessel that comes from the heart and supplies blood to the entire body. (seattlechildrens.org)
  • Even when repaired in childhood, ongoing follow-up as an adult is required to screen for abnormal growth of the aorta, re-narrowing of the aorta and heart valve disease that requires surgery. (emoryhealthcare.org)
  • The ascending aorta begins at the opening of the aortic valve in the left ventricle of the heart. (wikipedia.org)
  • The aorta begins at the top of the left ventricle, the heart 's muscular pumping chamber. (webmd.com)
  • The heart pumps blood from the left ventricle into the aorta through the aortic valve. (webmd.com)
  • The ascending aorta rises up from the heart and is about 2 inches long. (webmd.com)
  • A probe placed on the chest projects ultrasound waves off the aorta and heart. (webmd.com)
  • You or your child has been asked to have testing to image (make pictures of) the heart and/or aorta (or both). (massgeneral.org)
  • What are the different types of tests to image the heart and aorta? (massgeneral.org)
  • There are many types of tests to image (take a picture of) your child's heart and/or aorta (large artery that runs down the center of the body) and its branches. (massgeneral.org)
  • These tests can check the size and shape of the heart and aorta. (massgeneral.org)
  • The aorta is a large blood vessel that branches off from the heart and pumps oxygen-rich blood back into the body. (reference.com)
  • The function of the aorta is to pump this new oxygen-rich blood from the left ventricle of the heart, where the oxygenated blood is deposited, and circulate it back into the body. (reference.com)
  • Here's how a healthy heart and aorta work: Blood that needs oxygen comes from all over the body and enters the right side of the heart, which pumps it to the lungs. (rchsd.org)
  • The left side of the heart finishes up by pumping the blood out through the aorta. (rchsd.org)
  • The aorta originates from the left ventricle of the heart. (healthline.com)
  • In a statement, Gary Hardgrave says when he went to Australia for Christmas, doctors detected a tear in his Aorta, the body's main artery that extends from the heart to the abdomen. (radionz.co.nz)
  • This is a narrowing of the valve between the left ventricle of the heart and aorta (aortic stenosis) or the left atrium and left ventricle (mitral stenosis). (childrensmn.org)
  • With this defect, a portion of the large blood vessel that carries blood from the heart to the rest of the body (aorta) is abnormally narrowed or pinched. (healthwise.net)
  • Innervation of the heart and aorta of Manduca sexta was studied by using anatomic, neuronal tracing and immunocytochemical techniques. (nih.gov)
  • The larval heart and aorta seem to lack innervation, but a neurohemal system for the release of a cardioactive peptide is associated with the larval alary muscles. (nih.gov)
  • The aorta is the main artery that carries blood away from your heart to the rest of your body. (heart.org)
  • An aortic dissection is a split between the layers of the aorta that traps blood coming from the heart. (heart.org)
  • Because the aorta travels from above the heart to below the navel, severe pain may occur at any place along this major vessel. (heart.org)
  • The thoracic aorta , heart and other great vessels. (wikidoc.org)
  • The aorta (generally pronounced eɪˈɔːtə or "ay-orta") is the largest artery in the human body , originating from the left ventricle of the heart and bringing oxygenated blood to all parts of the body in the systemic circulation . (wikidoc.org)
  • The aorta is the main artery that carries oxygenated blood out of the heart to the body. (chop.edu)
  • The aorta is the large blood vessel that sends oxygen-rich blood (red blood) from the heart out to the body. (healthlinkbc.ca)
  • Fluoroquinolone antibiotics can, in some patients, increase the occurrence of rare but serious ruptures or tears in the main artery of the body, called the aorta, a US Food and Drug Administration (FDA) review found. (raps.org)
  • During surgery, the narrowed part of the aorta will be removed or opened. (medlineplus.gov)
  • Recent Examples on the Web The cause was complications following surgery for a torn aorta , said a son, Maury Peiperl. (merriam-webster.com)
  • BostonGlobe.com , "Adam Peiperl, creator of kinetic light sculptures, dies at 84 - The Boston Globe," 5 Dec. 2019 The cause was complications following surgery for a torn aorta , said a son, Maury Peiperl. (merriam-webster.com)
  • Aneurysmal ascending aortas were collected from elective aortic surgery, and normal aortas from transplant donors, and dissected aortas from surgery for aortic dissection. (ctsnet.org)
  • Surgery can repair tortuous aorta, says InnovateUs. (reference.com)
  • Abdominal ultrasound and contrast-enhanced computerized tomography revealed an infrarenal abdominal aorta aneurysm in a 41-year-old woman, but, on surgery, retroperitoneal fibrosis surrounding the aorta was detected. (hindawi.com)
  • The clinical enquiry for thoracoabdominal CTA included: a) follow-up after thoracic vascular surgery or endovascular repair, b) follow-up of untreated ascending aorta aneurysm or untreated dissection, c) suspected acute aortic syndrome. (thefreedictionary.com)
  • for this reason, the patient underwent elective ascending aorta replacement and conservative aortic valve surgery at age 5. (thefreedictionary.com)
  • In our study, mice with normal or moderately stressed aortas received either ciprofloxacin or placebo and after four weeks we looked at their aortas," said senior author Dr. Ying H. Shen , director of the Aortic Diseases Research Laboratory and associate professor of surgery at Baylor College of Medicine. (bcm.edu)
  • Occasionally, the aorta becomes narrow again and balloon catheterization or surgery will be required. (chop.edu)
  • Surgery is needed to repair the aorta. (healthlinkbc.ca)
  • In surgery, the doctor will take out the narrowed part of the aorta and then reattach the ends together. (healthlinkbc.ca)
  • To the Editor: We report a strategy for an asymptomatic anastomotic pseudoaneurysm that occurred 30 years after aorta surgery. (lww.com)
  • The aorta is the largest artery in the body. (webmd.com)
  • A tortuous aorta happens when the largest artery in the body twists in an unnatural and potentially dangerous way, according to InnovateUs. (reference.com)
  • Stiffness of the aorta, the largest artery in the body, may be a significant risk factor for developing dementia, according to new research from the University of Pittsburgh. (psychcentral.com)
  • When the tissue tightens and allows the ductus arteriosus to close normally after birth, this extra tissue may also tighten and narrow the aorta. (cdc.gov)
  • The aorta is the large artery that carries oxygen-rich (red) blood from the left ventricle to the body. (choc.org)
  • From April 2002 to November 2014, patients referred to our Department with a diagnosis of acute transection of thoracic aorta will be studied by preoperative Computed Tomography (CT) evaluation in order to perform thoracic endovascular aortic repair (TEVAR) with left subclavian artery coverage. (clinicaltrials.gov)
  • Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta. (ahajournals.org)
  • The present study investigated the role of arachidonic acid and acetylcholine in mediating endothelium-dependent relaxations of rabbit aorta. (ahajournals.org)
  • Arachidonic acid and acetylcholine had no effect on denuded rabbit aorta. (ahajournals.org)
  • Incubation of rabbit aorta with [14C]arachidonic acid resulted in the synthesis of major radioactive metabolites that comigrated with the prostaglandins and hydroxyeicosatetraenoic acids. (ahajournals.org)
  • Therefore, these data suggest that in rabbit aorta, arachidonic acid-induced relaxations are mediated by an endothelium-dependent factor (or factors) that differs from the factor (or factors) released by acetylcholine. (ahajournals.org)
  • The aorta carries blood away from the left ventricle and circulates it into the systemic circuit. (reference.com)
  • A common association is a bicuspid aortic valve, in which the aortic valve between the left ventricle and aorta has two leaflets instead of the normal three. (rchsd.org)
  • In the abdominal cavity the aorta gives off a number of branches, which form an extensive network supplying blood to the stomach, liver, pancreas, spleen, small and large intestines, kidneys, reproductive glands, and other organs. (britannica.com)
  • The abdominal aorta is the largest artery in the abdominal cavity . (bionity.com)
  • The abdominal aorta supplies blood to much of the abdominal cavity. (bionity.com)
  • Type B: Intimal tear not involving the ascending aorta (in the descending aorta distal to the left subclavian artery and limited to the descending aorta). (edu.au)
  • As part of the aorta , it is a direct continuation of descending aorta (of the thorax). (bionity.com)
  • The ascending aorta is contained within the pericardium, and is enclosed in a tube of the serous pericardium, common to it and the pulmonary artery. (wikipedia.org)
  • These two blood vessels twist around each other, causing the aorta to start out posterior to the pulmonary trunk, but end by twisting to its right and anterior side. (wikipedia.org)
  • It serves in the foetus to carry the blood from the trunk of the pulmonary artery direct to the aorta instead of passing into the lungs. (chestofbooks.com)
  • It then goes back through the pulmonary vein to the left chambers and is pumped through the aorta and out into the body again. (childrensmn.org)
  • The earliest physical signs of atherosclerosis are present in the abdominal aorta, and aortic intima-media thickness is considered the best non-invasive measure of structural health of the vasculature in children, suggesting a putative mechanism by which maternal adiposity may influence the risk of later cardiovascular disease in the offspring," they wrote. (medpagetoday.com)