Agents used to treat infections with bacteria of the genus TREPONEMA. This includes SYPHILIS & YAWS.
The causative agent of venereal and non-venereal syphilis as well as yaws.
Infections with bacteria of the genus TREPONEMA.
Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)
Serologic tests for syphilis.
A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.

Treatment of neurosyphilis with ceftriaxone. (1/6)

The first choice treatment for late syphilis is penicillin. Other than doxycycline, which penetrates the CNS, there are few alternatives for the treatment of neurosyphilis. We report a case of successful treatment of symptomatic neurosyphilis with parenteral ceftriaxone.  (+info)

Syphilis in adults. (2/6)

Syphilis is a sexually transmitted disease with protean manifestations resulting from infection by Treponema pallidum. It is systemic early from the outset, the primary pathology being vasculitis. Acquired syphilis can be divided into primary, secondary, latent, and tertiary stages. The infection can also be transmitted vertically resulting in congenital syphilis, and occasionally by blood transfusion and non-sexual contact. Diagnosis is mainly by dark field microscopy in early syphilis and by serological tests. The management in the tropics depends on the diagnostic facilities available: in resource poor countries, primary syphilis is managed syndromically as for anogenital ulcer. The introduction of rapid "desktop" serological tests may simplify and promote widespread screening for syphilis. The mainstay of treatment is with long acting penicillin. Syphilis promotes the transmission of HIV and both infections can simulate and interact with each other. Treponemes may persist despite effective treatment and may have a role in reactivation in immunosuppressed patients. Partner notification, health education, and screening in high risk populations and pregnant women to prevent congenital syphilis are essential aspects in controlling the infection.  (+info)

Clinical case of seroconversion for syphilis following a needlestick injury: why not take a prophylaxis? (3/6)

A 47-year-old woman was pricked accidentally with a needle previously used for a neurosyphilitic man. At day 0 she had no positive laboratory results for the infection, while the source, at day 1, had TPHA positive, but no post-exposure prophylaxis (PEP) against syphilis was prescribed. The subject missed the day 30 follow-up, and underwent our visit at day 90, when she showed no clinical signs, but she seroconverted (VDRL = positive 1/2; TPHA = positive 1/320; FTA-Abs IgG and IgM = present). She started antibiotic therapy, and currently her serological status is VDRL = positive 1/2, TPHA = positive 1/160, FTA-Abs IgM = negative.  (+info)

Cerebrospinal fluid human immunodeficiency virus viral load in patients with neurosyphilis. (4/6)

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Serological response to treatment of syphilis according to disease stage and HIV status. (5/6)

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Syphilis treatment response among HIV-discordant couples in Zambia and Rwanda. (6/6)

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Antitreponemal agents are medications used to treat infections caused by Treponema pallidum, the bacterium responsible for syphilis. These medications work by targeting the bacterium and preventing it from multiplying and spreading within the body. There are several different types of antitreponemal agents, including penicillin, tetracyclines, and macrolides. These medications are typically given orally or by injection, and the duration of treatment depends on the stage and severity of the infection. It is important to complete the full course of treatment as prescribed by a healthcare provider to ensure that the infection is fully eradicated and to prevent the development of complications.

Treponemal infections are a group of bacterial infections caused by the bacterium Treponema pallidum. These infections are primarily sexually transmitted and can also be transmitted through direct contact with open sores or through the placenta during pregnancy. The most well-known treponemal infection is syphilis, which can be divided into four stages: primary, secondary, latent, and tertiary. Other treponemal infections include yaws, pinta, and bejel. These infections can cause a range of symptoms, including skin rashes, ulcers, fever, and joint pain. Treatment typically involves antibiotics, although some forms of the infection may be resistant to certain antibiotics.

Neurosyphilis is a neurological complication of syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It occurs when the infection spreads from the bloodstream to the central nervous system (CNS), including the brain and spinal cord. The symptoms of neurosyphilis can vary depending on the stage of the infection and the specific areas of the brain and spinal cord affected. Early neurosyphilis may present with headache, fever, and malaise, while late neurosyphilis can cause more severe symptoms such as seizures, cognitive impairment, and paralysis. Diagnosis of neurosyphilis typically involves a combination of clinical examination, laboratory testing, and imaging studies such as MRI or CT scans. Treatment involves antibiotics, usually penicillin, to eliminate the infection and prevent further damage to the nervous system. Early diagnosis and treatment are crucial to prevent long-term neurological complications and disability.

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It is transmitted through direct contact with an infected person's sores or other mucous membranes during sexual activity, including vaginal, anal, and oral sex. Syphilis can also be transmitted from mother to child during pregnancy or childbirth. Syphilis has three stages: primary, secondary, and tertiary. The primary stage is characterized by a single, painless sore called a chancre, usually on the genital area, anus, or mouth. The secondary stage can occur weeks to months after the initial infection and is characterized by a rash on the skin and mucous membranes, fever, swollen lymph nodes, and sore throat. The tertiary stage, which can occur years after the initial infection, can cause serious damage to the heart, brain, and other organs. Syphilis can be diagnosed through a blood test, and treatment typically involves antibiotics. If left untreated, syphilis can lead to serious health complications and even death. It is important to practice safe sex and get tested regularly for sexually transmitted infections.

Antibodies, Bacterial are proteins produced by the immune system in response to bacterial infections. They are also known as bacterial antibodies or bacterial immunoglobulins. These antibodies are specific to bacterial antigens, which are molecules found on the surface of bacteria that trigger an immune response. When the immune system detects a bacterial infection, it produces antibodies that bind to the bacterial antigens and mark them for destruction by other immune cells. This helps to neutralize the bacteria and prevent them from causing harm to the body. Bacterial antibodies can be detected in the blood or other bodily fluids using laboratory tests. These tests are often used to diagnose bacterial infections and to monitor the effectiveness of antibiotic treatments.

... antitreponemal agents MeSH D27.505.954.122.085.255 - antitubercular agents MeSH D27.505.954.122.085.255.135 - antibiotics, ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Categories: Antitreponemal Agents Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Leishmania is a protozoan agent commonly seen in Asia, Africa, and South America. It is carried by the sand fly vector and is ... Perform an antitreponemal testing on the infant and cord or placenta. Perform long bone radiographs and other tests, as ... Tuberculosis and leprosy are 2 mycobacterial infections that may be causative agents in the pathogenesis of interstitial ... ICG angiography can also be useful in monitoring antitreponemal therapy. Late-phase scattered hyperfluorescent spots and ...
... antitreponemal agents MeSH D27.505.954.122.085.255 - antitubercular agents MeSH D27.505.954.122.085.255.135 - antibiotics, ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Antitreponemal Agents [D27.505.954.122.085.222] Antitreponemal Agents * Antitubercular Agents [D27.505.954.122.085.255] ...
The epidemiology of DLHA is thought to have been impacted by the widespread employment of antitreponemal therapy. [19] ... A definitive causative agent is rarely identified.. Viral infections that have been associated with acute Donath-Landsteiner ...
For these persons, infections caused by acyclovir-resistant strains require selection of alternate antiviral agents. First ... Specific antitreponemal IgM antibody detected by a testing method that has been given provisional or standard status by CDC ... antitreponemal IgM antibody by a testing method recognized by CDC as having either provisional or standard status; -- ... coinfection with another STD agent exists, c) the patient is infected with HIV, d) treatment was not taken as instructed, or e ...
Markers of past syphilis in HIV infection comparing Captia Syphilis G anti-treponemal IgG enzyme immunoassay with other ... the causative agents of syphilis, yaws, pinta, bejel, and endemic syphilis. The test is a passive agglutination procedure based ... and finely divided charcoal particles as a visualizing agent. In the test, the RPR antigen is mixed with unheated or heated ...
Studies in the Pacific have found a seroprevalence of antitreponemal antibodies of ,30% in several communities (7,17) and a ... The availability of a well-tolerated oral agent has prompted WHO to develop a new eradication strategy, known as the Morges ...
Identify whether the patient was exposed to agents through unusual travel, occupational exposure or intravenous drug use ... Anti-treponemal testing. Tuberculosis. CXRIFN-γ release assay. Lyme disease. Serology (only in patient with a history ...
46. Cronje, L., Edmondson, N., Eisenach, K.D. and Bornman, L. (2005) Iron and Iron Chelating Agents Modulate Mycobacterium ... Serological diagnosis of Syphilis was based on by detection of anti-treponemal antibody test using commercial Treponema ... Cronje, L., Edmondson, N., Eisenach, K.D. and Bornman, L. (2005) Iron and Iron Chelating Agents Modulate Mycobacterium ...
We aimed to identify potential additional etiological agents of CU in a yaws-endemic region. Methods: This population-based ... FINDINGS: Amoxicillin, ceftriaxone, several oral cephalosporins, tedizolid, and dalbavancin exhibited anti-treponemal activity ... Background: Treponema pallidum subsp pertenue and Haemophilus ducreyi are causative agents of cutaneous ulcer (CU) in yaws- ... However, a significant proportion of CU patients remain polymerase chain reaction (PCR) negative for both bacterial agents. ...
Antitreponemal agent (substance). Code System Preferred Concept Name. Antitreponemal agent (substance). Concept Status. ...
Antitreponemal Agents. Registry Number:. 139-93-5 CAS Type 1 Name:. Phenol, 4,4-(1,2-diarsenediyl)bis(2-amino)-, ...
Anti-Bacterial Agents [D27.505.954.122.085] * Antitreponemal Agents [D27.505.954.122.085.222] * Antitubercular Agents [D27.505. ... Antitreponemal Agents Preferred Concept UI. M0001512. Registry Number. 0. Scope Note. Agents used to treat infections with ... Antitreponemal Agents Preferred Term Term UI T003055. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1974). ... Antisyphilitic Agents Narrower Concept UI. M0001513. Registry Number. 0. Terms. Antisyphilitic Agents Preferred Term Term UI ...
Anti-Bacterial Agents [D27.505.954.122.085] * Antitreponemal Agents [D27.505.954.122.085.222] * Antitubercular Agents [D27.505. ... Antitreponemal Agents Preferred Concept UI. M0001512. Registry Number. 0. Scope Note. Agents used to treat infections with ... Antitreponemal Agents Preferred Term Term UI T003055. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1974). ... Antisyphilitic Agents Narrower Concept UI. M0001513. Registry Number. 0. Terms. Antisyphilitic Agents Preferred Term Term UI ...
See also Antitreponemal Agents See also Neurosyphilis See also Syphilis Serodiagnosis Syphilis Serodiagnosis WC 160.5 ...
Use T-20 as Single New Agent for Experienced Patients? I have a number of patients who are resistant to all currently available ... Is HAART beneficial as adjunctive treatment in addition to specific antitreponemal antibiotics?. Medscape HIV/AIDS, September ...
The genome of Treponema pallidum: new light on the agent of syphilis. Weinstock GM, Hardham JM, McLeod MP, Sodergren EJ, Norris ... pallidum from isolate UZ1974 using Anti-Treponemal Antibodies Enrichment: First complete whole genome sequence obtained ... pallidum: surveillance and epidemiology of the causative agent of syphilis. Grillova L, Jolley K, Šmajs D, Picardeau M. ... pallidum (TPA) is the causative agent of syphilis. Genetic analyses of TPA reference strains and human clinical isolates have ...
No difference was found between the two agents, both giving pain relief and being safe and acceptable to the majority of ... The enzyme linked immunosorbent assays for detection of RF and antitreponemal IgM antibodies are performed on the same plate. ... It is concluded that in this short-term study, both agents offer effective and safe treatment for osteoarthritis. PMID- 3894259 ... A closer examination of the relationship between differentiation and the presence or absence of mitogenic agents in the medium ...
... anti-foaming agent,noun,E0438501,foaming agent,noun,E0583387,no anti-,anti-foam,adj,E0222816,foam,verb,E0028347,no anti-,anti- ... anti-treponemal,noun,E0009764,treponemal,adj,E0062017,no anti-,anti-trust,adj,E0203576,trust,verb,E0062396,no anti-,anti- ... antifoaming agent,noun,E0438501,foaming agent,noun,E0583387,no anti,antifoam,adj,E0222816,foam,verb,E0028347,no anti,antifoam, ... antitreponemal,noun,E0009764,treponemal,adj,E0062017,no anti,antitrichomonal,noun,E0009766,trichomonal,adj,E0062086,no anti, ...
33] have shown antitreponemal activity in clinical trials; however, they currently are recommended only as alternative ...
Studies in the Pacific have found a seroprevalence of antitreponemal antibodies of ,30% in several communities (7,17) and a ... The availability of a well-tolerated oral agent has prompted WHO to develop a new eradication strategy, known as the Morges ...
Contact stomatitis associated with consumption of cinnamon flavoring agents is a relatively uncommon disorder. Of relevance, ... specimen obtained by punch biopsy revealed features suggestive of syphilis and immunohistochemical staining with antitreponemal ...
... anti-foaming agent,noun,E0438501,foaming agent,noun,E0583387,no anti-,anti-foam,adj,E0222816,foam,verb,E0028347,no anti-,anti- ... anti-treponemal,noun,E0009764,treponemal,adj,E0062017,no anti-,anti-trust,adj,E0203576,trust,verb,E0062396,no anti-,anti- ... antifoaming agent,noun,E0438501,foaming agent,noun,E0583387,no anti,antifoam,adj,E0222816,foam,verb,E0028347,no anti,antifoam, ... antitreponemal,noun,E0009764,treponemal,adj,E0062017,no anti,antitrichomonal,noun,E0009766,trichomonal,adj,E0062086,no anti, ...
  • The Serodia TP-PA test is a treponemal test for the serologic detection of antibodies to the various species and subspecies of pathogenic Treponema , the causative agents of syphilis, yaws, pinta, bejel, and endemic syphilis. (cdc.gov)
  • The Serodia TP-PA test is a treponemal test for the serologic detection of antibodies to the various species and subspecies of pathogenic Treponema , the causative agents of syphilis, yaws, pinta, bejel, and endemic syphilis. (cdc.gov)
  • Histopathological examination of the specimen obtained by punch biopsy revealed features suggestive of syphilis and immunohistochemical staining with antitreponemal antibody confirmed its diagnosis with the detection of numerous Treponema pallidum in the specimen. (bvsalud.org)
  • Agents used to treat infections with bacteria of the genus TREPONEMA . (nih.gov)