Antitreponemal Agents
Neurosyphilis
Treatment of neurosyphilis with ceftriaxone. (1/6)
The first choice treatment for late syphilis is penicillin. Other than doxycycline, which penetrates the CNS, there are few alternatives for the treatment of neurosyphilis. We report a case of successful treatment of symptomatic neurosyphilis with parenteral ceftriaxone. (+info)Syphilis in adults. (2/6)
Syphilis is a sexually transmitted disease with protean manifestations resulting from infection by Treponema pallidum. It is systemic early from the outset, the primary pathology being vasculitis. Acquired syphilis can be divided into primary, secondary, latent, and tertiary stages. The infection can also be transmitted vertically resulting in congenital syphilis, and occasionally by blood transfusion and non-sexual contact. Diagnosis is mainly by dark field microscopy in early syphilis and by serological tests. The management in the tropics depends on the diagnostic facilities available: in resource poor countries, primary syphilis is managed syndromically as for anogenital ulcer. The introduction of rapid "desktop" serological tests may simplify and promote widespread screening for syphilis. The mainstay of treatment is with long acting penicillin. Syphilis promotes the transmission of HIV and both infections can simulate and interact with each other. Treponemes may persist despite effective treatment and may have a role in reactivation in immunosuppressed patients. Partner notification, health education, and screening in high risk populations and pregnant women to prevent congenital syphilis are essential aspects in controlling the infection. (+info)Clinical case of seroconversion for syphilis following a needlestick injury: why not take a prophylaxis? (3/6)
A 47-year-old woman was pricked accidentally with a needle previously used for a neurosyphilitic man. At day 0 she had no positive laboratory results for the infection, while the source, at day 1, had TPHA positive, but no post-exposure prophylaxis (PEP) against syphilis was prescribed. The subject missed the day 30 follow-up, and underwent our visit at day 90, when she showed no clinical signs, but she seroconverted (VDRL = positive 1/2; TPHA = positive 1/320; FTA-Abs IgG and IgM = present). She started antibiotic therapy, and currently her serological status is VDRL = positive 1/2, TPHA = positive 1/160, FTA-Abs IgM = negative. (+info)Cerebrospinal fluid human immunodeficiency virus viral load in patients with neurosyphilis. (4/6)
(+info)Serological response to treatment of syphilis according to disease stage and HIV status. (5/6)
(+info)Syphilis treatment response among HIV-discordant couples in Zambia and Rwanda. (6/6)
(+info)Antitreponemal agents are medications used to treat infections caused by Treponema pallidum, the bacterium responsible for syphilis. These medications work by targeting the bacterium and preventing it from multiplying and spreading within the body. There are several different types of antitreponemal agents, including penicillin, tetracyclines, and macrolides. These medications are typically given orally or by injection, and the duration of treatment depends on the stage and severity of the infection. It is important to complete the full course of treatment as prescribed by a healthcare provider to ensure that the infection is fully eradicated and to prevent the development of complications.
Treponemal infections are a group of bacterial infections caused by the bacterium Treponema pallidum. These infections are primarily sexually transmitted and can also be transmitted through direct contact with open sores or through the placenta during pregnancy. The most well-known treponemal infection is syphilis, which can be divided into four stages: primary, secondary, latent, and tertiary. Other treponemal infections include yaws, pinta, and bejel. These infections can cause a range of symptoms, including skin rashes, ulcers, fever, and joint pain. Treatment typically involves antibiotics, although some forms of the infection may be resistant to certain antibiotics.
Neurosyphilis is a neurological complication of syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It occurs when the infection spreads from the bloodstream to the central nervous system (CNS), including the brain and spinal cord. The symptoms of neurosyphilis can vary depending on the stage of the infection and the specific areas of the brain and spinal cord affected. Early neurosyphilis may present with headache, fever, and malaise, while late neurosyphilis can cause more severe symptoms such as seizures, cognitive impairment, and paralysis. Diagnosis of neurosyphilis typically involves a combination of clinical examination, laboratory testing, and imaging studies such as MRI or CT scans. Treatment involves antibiotics, usually penicillin, to eliminate the infection and prevent further damage to the nervous system. Early diagnosis and treatment are crucial to prevent long-term neurological complications and disability.
Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It is transmitted through direct contact with an infected person's sores or other mucous membranes during sexual activity, including vaginal, anal, and oral sex. Syphilis can also be transmitted from mother to child during pregnancy or childbirth. Syphilis has three stages: primary, secondary, and tertiary. The primary stage is characterized by a single, painless sore called a chancre, usually on the genital area, anus, or mouth. The secondary stage can occur weeks to months after the initial infection and is characterized by a rash on the skin and mucous membranes, fever, swollen lymph nodes, and sore throat. The tertiary stage, which can occur years after the initial infection, can cause serious damage to the heart, brain, and other organs. Syphilis can be diagnosed through a blood test, and treatment typically involves antibiotics. If left untreated, syphilis can lead to serious health complications and even death. It is important to practice safe sex and get tested regularly for sexually transmitted infections.
Antibodies, Bacterial are proteins produced by the immune system in response to bacterial infections. They are also known as bacterial antibodies or bacterial immunoglobulins. These antibodies are specific to bacterial antigens, which are molecules found on the surface of bacteria that trigger an immune response. When the immune system detects a bacterial infection, it produces antibodies that bind to the bacterial antigens and mark them for destruction by other immune cells. This helps to neutralize the bacteria and prevent them from causing harm to the body. Bacterial antibodies can be detected in the blood or other bodily fluids using laboratory tests. These tests are often used to diagnose bacterial infections and to monitor the effectiveness of antibiotic treatments.
List of MeSH codes (D27)
Advanced Search Results - Public Health Image Library(PHIL)
Interstitial Keratitis: Overview, Pathophysiology, Epidemiology
List of MeSH codes (D27) - Wikipedia
DeCS
Donath-Landsteiner Hemolytic Anemia: Practice Essentials, Pathophysiology, Etiology
WONDER STD Document
L36 C
Mathematical Modeling of Programmatic Requirements for Yaws Eradication - Volume 23, Number 1-January 2017 - Emerging...
Practical Diagnostic Approach to Uveitis
High Incidence of Pulmonary Tuberculosis in ART Naive Remunerated Blood Donors with Human Immunodeficiency Virus Type-1...
Pesquisa | Portal Regional da BVS
Code System Concept
DeCS
MeSH Browser
MeSH Browser
Classification-Index
HIV/AIDS Ask The Experts - Index
Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing...
PMID- 3894220
Prefix: anti
Syphilis Treatment & Management: Approach Considerations, Antibiotic Therapy, Surgical Care
Mathematical Modeling of Programmatic Requirements for Yaws Eradication - Volume 23, Number 1-January 2017 - Emerging...
Pesquisa | Biblioteca Virtual em Saúde - BRASIL
Prefix: anti
Yaws1
- The Serodia TP-PA test is a treponemal test for the serologic detection of antibodies to the various species and subspecies of pathogenic Treponema , the causative agents of syphilis, yaws, pinta, bejel, and endemic syphilis. (cdc.gov)
SYPHILIS2
- The Serodia TP-PA test is a treponemal test for the serologic detection of antibodies to the various species and subspecies of pathogenic Treponema , the causative agents of syphilis, yaws, pinta, bejel, and endemic syphilis. (cdc.gov)
- Histopathological examination of the specimen obtained by punch biopsy revealed features suggestive of syphilis and immunohistochemical staining with antitreponemal antibody confirmed its diagnosis with the detection of numerous Treponema pallidum in the specimen. (bvsalud.org)
TREPONEMA1
- Agents used to treat infections with bacteria of the genus TREPONEMA . (nih.gov)